TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32738891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35833889 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 34480127 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 34061695 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 32648022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35836287 — Surrogate Endpoint (SUR): Blood pressure
Study 33808526 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33808526 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33808526 — Monitoring Biomarker (MOI): Cell-free DNA
Study 33851329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33851329 — Predictive Biomarker (PRD): TOMM20 mRNA
Genes: TOMM20; KIAA0016
Study 33851329 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 35871058 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33130104 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 35115180 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35800292 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 36233606 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36233606 — Surrogate Endpoint (SUR): Blood pressure
Study 32660675 — Surrogate Endpoint (SUR): Blood pressure
Study 32678299 — Surrogate Endpoint (SUR): Blood pressure
Study 32008296 — Surrogate Endpoint (SUR): Blood pressure
Study 36414172 — Safety Biomarker (SAF): Hyaluronic acid
Study 32665311 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 33882864 — Surrogate Endpoint (SUR): Blood pressure
Study 34384109 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 34384109 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 34543613 — Predictive Biomarker (PRD): Hormone receptor
Study 34567487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34567487 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 33642330 — Surrogate Endpoint (SUR): Blood pressure
Study 32505213 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 32505213 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 33401024 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 36302533 — Predictive Biomarker (PRD): NUBP1 mRNA
Genes: NUBP1; NBP; NBP1
Study 36302533 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36302533 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32091668 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 33500177 — Predictive Biomarker (PRD): GRK5 mRNA
Genes: GRK5; GPRK5
Study 33500177 — Predictive Biomarker (PRD): CYP1B1 mRNA
Genes: CYP1B1
Study 35172273 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33300961 — Predictive Biomarker (PRD): Hormone receptor
Study 35811080 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35585641 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 33252490 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33252490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33252490 — Surrogate Endpoint (SUR): Blood pressure
Study 36190186 — Monitoring Biomarker (MOI): Cell-free DNA
Study 33277736 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 34423506 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 35785477 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 33493551 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32414353 — Predictive Biomarker (PRD): MUTYH mRNA
Genes: MUTYH; MYH
Study 32414353 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 32078484 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34907783 — Predictive Biomarker (PRD): CD81 mRNA
Genes: CD81; TAPA1; TSPAN28
Study 34907783 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 34907783 — Predictive Biomarker (PRD): CD9 mRNA
Genes: CD9; MIC3; TSPAN29; GIG2
Study 36376167 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 32305424 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 32305424 — Safety Biomarker (SAF): Hyaluronic acid
Study 34191437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34191437 — Surrogate Endpoint (SUR): Blood pressure
Study 35190584 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 34493431 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 34493431 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36394838 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 34347093 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 34347093 — Surrogate Endpoint (SUR): Serum calcium
Study 36215414 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36215414 — Surrogate Endpoint (SUR): Blood pressure
Study 33350678 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 32466446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32466446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35484607 — Surrogate Endpoint (SUR): Blood pressure
Study 32826114 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 32559474 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32559474 — Surrogate Endpoint (SUR): Blood pressure
Study 35264106 — Surrogate Endpoint (SUR): Blood pressure
Study 32627438 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study 34389701 — Predictive Biomarker (PRD): SIRT6 mRNA
Genes: SIRT6; SIR2L6
Study 34086190 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34086190 — Surrogate Endpoint (SUR): Blood pressure
Study 32107818 — Surrogate Endpoint (SUR): Blood pressure
Study 34048641 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 34086518 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 34701458 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32924561 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 32924561 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 33318079 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32960272 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 32960272 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35030530 — Surrogate Endpoint (SUR): Serum creatinine
Study 33835084 — Surrogate Endpoint (SUR): Blood pressure
Study 35392908 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32051972 — Safety Biomarker (SAF): Hyaluronic acid
Study 33349641 — Surrogate Endpoint (SUR): Blood pressure
Study 32952230 — Safety Biomarker (SAF): Interleukin 1
Study 36137691 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 33657007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36278359 — Surrogate Endpoint (SUR): Blood pressure
Study 33096356 — Predictive Biomarker (PRD): AFF1 mRNA
Genes: AFF1; AF4; FEL; MLLT2; PBM1
Study 36401445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33955628 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 33078649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36375479 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33592815 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36159170 — Surrogate Endpoint (SUR): Blood pressure
Study 36159170 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 36159170 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32037254 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32248805 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32248805 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32198616 — Surrogate Endpoint (SUR): Bone mineral density
Study 33283766 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36334050 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 34438976 — Safety Biomarker (SAF): Hyaluronic acid
Study 34438976 — Surrogate Endpoint (SUR): Bacterial count
Study 34397104 — Predictive Biomarker (PRD): TNR mRNA
Genes: TNR
Study 32032923 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32032923 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 33784428 — Surrogate Endpoint (SUR): Bone mineral density
Study 35280426 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36239883 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33572416 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 33332813 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32861377 — Surrogate Endpoint (SUR): Serum creatinine
Study 35320494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35320494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32521538 — Safety Biomarker (SAF): BDNF
Study 34825613 — Surrogate Endpoint (SUR): Blood pressure
Study 32062048 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 34971614 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 32127255 — Surrogate Endpoint (SUR): Blood pressure
Study 34402887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33509035 — Surrogate Endpoint (SUR): Blood pressure
Study 32959586 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32959586 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34643650 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 34643650 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 34643650 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 35775789 — Surrogate Endpoint (SUR): Blood pressure
Study 35637845 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35637845 — Surrogate Endpoint (SUR): Serum uric acid
Study 35637845 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 33686683 — Surrogate Endpoint (SUR): Serum sodium
Study 33686683 — Surrogate Endpoint (SUR): Serum potassium
Study 36197213 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 35238614 — Surrogate Endpoint (SUR): Blood pressure
Study 33448139 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 33448139 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study 33448139 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 33448139 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33448139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33448139 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32815405 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 32815405 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 32815405 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 35451612 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 33386040 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33982141 — Surrogate Endpoint (SUR): Blood pressure
Study 35401282 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 35401282 — Predictive Biomarker (PRD): L3MBTL4 mRNA
Genes: L3MBTL4
Study 33663489 — Surrogate Endpoint (SUR): Blood pressure
Study 35397664 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 35397664 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 32210349 — Safety Biomarker (SAF): Protein AMBP
Genes: AMBP; HCP; ITIL
Study 33450335 — Surrogate Endpoint (SUR): Serum creatinine
Study 33450335 — Surrogate Endpoint (SUR): Blood pressure
Study 34897499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35275761 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34508090 — Surrogate Endpoint (SUR): Blood pressure
Study 32514677 — Surrogate Endpoint (SUR): Bone mineral density
Study 34729862 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35073825 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33469276 — Surrogate Endpoint (SUR): Bone mineral density
Study 35048253 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 36136603 — Predictive Biomarker (PRD): MYOD1 mRNA
Genes: MYOD1; BHLHC1; MYF3; MYOD
Study 36136603 — Predictive Biomarker (PRD): MYF5 mRNA
Genes: MYF5; BHLHC2
Study 36136603 — Predictive Biomarker (PRD): MYF6 mRNA
Genes: MYF6; BHLHC4; MRF4
Study 33040817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33040817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34130243 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 616026366 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35216619 — Predictive Biomarker (PRD): LAMB2 mRNA
Genes: LAMB2; LAMS
Study 35216619 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 33082181 — Surrogate Endpoint (SUR): Blood pressure
Study 35582957 — Surrogate Endpoint (SUR): Blood pressure
Study 34559182 — Surrogate Endpoint (SUR): Blood pressure
Study 33763720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33832307 — Predictive Biomarker (PRD): ITIH3 mRNA
Genes: ITIH3
Study 34995935 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34995935 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34995935 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 33256760 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 36168187 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 36168187 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 36168187 — Predictive Biomarker (PRD): TTLL5 mRNA
Genes: TTLL5; KIAA0998; STAMP
Study 35176163 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 35176163 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 33785752 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33785752 — Surrogate Endpoint (SUR): Blood pressure
Study 34237809 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34237809 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34237809 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35038612 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33459692 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 34232005 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 36241502 — Surrogate Endpoint (SUR): Blood pressure
Study 32090516 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 32131656 — Safety Biomarker (SAF): Hyaluronic acid
Study 32131656 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32131656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32131656 — Safety Biomarker (SAF): Interleukin 1
Study 34801353 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33989763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35685661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35685661 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 35685661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35313858 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33125033 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 32583886 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34528669 — Surrogate Endpoint (SUR): Blood pressure
Study 34250456 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34271286 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 36237142 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 34613430 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 34613430 — Surrogate Endpoint (SUR): Blood pressure
Study 35030040 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 32961319 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32961319 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 32892604 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32892604 — Surrogate Endpoint (SUR): Blood pressure
Study 33422518 — Surrogate Endpoint (SUR): Serum creatinine
Study 33355818 — Predictive Biomarker (PRD): PIR mRNA
Genes: PIR
Study 34787952 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 33219136 — Surrogate Endpoint (SUR): Blood pressure
Study 34637055 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 34637055 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 36137949 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 33847022 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 34785763 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 33539582 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 32305093 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 32807252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32807252 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32807252 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 32807252 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 32807252 — Predictive Biomarker (PRD): Small-inducible cytokine A11
Genes: CCL11; SCYA11
Study 32807252 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 35813842 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 35813842 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 35813842 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35813842 — Safety Biomarker (SAF): Reactive oxygen species
Study 35813842 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34181564 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33290405 — Surrogate Endpoint (SUR): Blood pressure
Study 33290405 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32078064 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 32078064 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 32576559 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32186048 — Surrogate Endpoint (SUR): Blood pressure
Study 35997173 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 35997173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35997173 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32964434 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 33682286 — Predictive Biomarker (PRD): AZIN2 mRNA
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 32698903 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 34520506 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 33168966 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 33168966 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 33168966 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 33168966 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study 32358398 — Predictive Biomarker (PRD): RASA1 mRNA
Genes: RASA1; GAP; RASA
Study 32507863 — Predictive Biomarker (PRD): MOXD1 mRNA
Genes: MOXD1; MOX; UNQ2493/PRO5780
Study 34508654 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 34508654 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33353965 — Surrogate Endpoint (SUR): Bone mineral density
Study 35292232 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 34371004 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 34371004 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 32902075 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA