TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32652973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32652973 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 33087100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35048240 — Surrogate Endpoint (SUR): Blood pressure
Study 34439282 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 33522927 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33522927 — Surrogate Endpoint (SUR): Blood pressure
Study 32227501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32227501 — Surrogate Endpoint (SUR): Blood pressure
Study 34533053 — Safety Biomarker (SAF): Glutamate dehydrogenase
Study 34533053 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 33318814 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 35639721 — Surrogate Endpoint (SUR): Blood pressure
Study 35451408 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 35451408 — Surrogate Endpoint (SUR): Pathological complete response
Study 33087330 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 33087330 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 35369705 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 33538091 — Surrogate Endpoint (SUR): Blood pressure
Study 34623507 — Safety Biomarker (SAF): Hyaluronic acid
Study 34807243 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 34807243 — Safety Biomarker (SAF): APOE
Genes: AD2
Study 33054727 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35447622 — Surrogate Endpoint (SUR): Blood pressure
Study 34664221 — Surrogate Endpoint (SUR): Sperm parameters
Study 34664221 — Surrogate Endpoint (SUR): Serum calcium
Study 32770661 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 32770661 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 32731424 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32731424 — Surrogate Endpoint (SUR): Blood pressure
Study 35485687 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32902928 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 35916128 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35916128 — Surrogate Endpoint (SUR): Blood pressure
Study 32646930 — Safety Biomarker (SAF): Interleukin 1
Study 33640347 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 32708428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32708428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34590717 — Predictive Biomarker (PRD): Anti-acetylcholine receptor antibody
Study 616795279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35251297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33961943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33961943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34033621 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33077866 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 33550815 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33550815 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32937620 — Surrogate Endpoint (SUR): Blood pressure
Study 32539787 — Surrogate Endpoint (SUR): Blood pressure
Study 33711390 — Predictive Biomarker (PRD): THAP11 mRNA
Genes: THAP11; HRIHFB2206
Study 33068140 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 33068140 — Surrogate Endpoint (SUR): Bone mineral density
Study 35320644 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33810049 — Surrogate Endpoint (SUR): Blood pressure
Study 32699327 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32071117 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 32071117 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 32071117 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 32071117 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32071117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32071117 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32071117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33920894 — Surrogate Endpoint (SUR): Blood pressure
Study 32535124 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33716121 — Safety Biomarker (SAF): Hyaluronic acid
Study 33716121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32170634 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32170634 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32170634 — Predictive Biomarker (PRD): Hormone receptor
Study 32170634 — Surrogate Endpoint (SUR): Pathological complete response
Study 35323633 — Surrogate Endpoint (SUR): Blood pressure
Study 36174143 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 32415555 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 32709643 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 34625057 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 32762109 — Surrogate Endpoint (SUR): Blood pressure
Study 35013615 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 35013615 — Predictive Biomarker (PRD): TAP1 mRNA
Genes: TAP1; ABCB2; PSF1; RING4; Y3
Study 35013615 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 616852759 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35771569 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34936531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32761980 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36361052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36361052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35912159 — Surrogate Endpoint (SUR): Blood pressure
Study 33515092 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 35135481 — Surrogate Endpoint (SUR): Serum potassium
Study 33077259 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 32962724 — Surrogate Endpoint (SUR): Blood pressure
Study 32770640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33121346 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32418886 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 616178325 — Surrogate Endpoint (SUR): Blood pressure
Study 616178325 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32102058 — Surrogate Endpoint (SUR): Blood pressure
Study 32102058 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33466128 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 33466128 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32286687 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32289518 — Surrogate Endpoint (SUR): Bone mineral density
Study 34922023 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34922023 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34922023 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 32150670 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 36275695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33220395 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32550915 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 32550915 — Predictive Biomarker (PRD): NDRG1 mRNA
Genes: NDRG1; CAP43; DRG1; RTP
Study 32550915 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32550915 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 35210111 — Safety Biomarker (SAF): Hyaluronic acid
Study 32133745 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 33246499 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36143964 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33355689 — Predictive Biomarker (PRD): FER mRNA
Genes: FER; TYK3
Study 35672893 — Monitoring Biomarker (MOI): HBV DNA
Study 35672893 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 616173846 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35552080 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 34564022 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34564022 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 34351386 — Safety Biomarker (SAF): Hyaluronic acid
Study 32273317 — Surrogate Endpoint (SUR): Blood pressure
Study 32311763 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33906842 — Surrogate Endpoint (SUR): Blood pressure
Study 34930386 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 32937634 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 34240125 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 32053149 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HSD3B1 mRNA
Genes: HSD3B1; 3BH; HSDB3A
Study 33673371 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 35388626 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33211349 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33211349 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 34934969 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33619820 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33531255 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 33531255 — Surrogate Endpoint (SUR): Bone mineral density
Study 33531255 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33970290 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 32459035 — Predictive Biomarker (PRD): Hormone receptor
Study 33308820 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 35319669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36478225 — Surrogate Endpoint (SUR): Blood pressure
Study 33053456 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 35345656 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36357806 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 35552673 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35552673 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35552673 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35552673 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 35552673 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 35552673 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 35552673 — Predictive Biomarker (PRD): Hormone receptor
Study 32248591 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33189562 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 33189562 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33189562 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33189562 — Predictive Biomarker (PRD): Hormone receptor
Study 35560470 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 35560470 — Surrogate Endpoint (SUR): Blood pressure
Study 32702276 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 36293365 — Predictive Biomarker (PRD): AQP3 mRNA
Genes: AQP3
Study 36293365 — Predictive Biomarker (PRD): OCLN mRNA
Genes: OCLN
Study 36293365 — Predictive Biomarker (PRD): KLK5 mRNA
Genes: KLK5; SCTE; UNQ570/PRO1132
Study 36293365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 33689702 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 33689702 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33689702 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 36065041 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33676384 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 35072922 — Surrogate Endpoint (SUR): Blood pressure
Study 33990652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 616374539 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33161904 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 35263746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32407514 — Surrogate Endpoint (SUR): Blood pressure
Study 35078841 — Surrogate Endpoint (SUR): Blood pressure
Study 36200875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36200875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35105593 — Predictive Biomarker (PRD); Safety Biomarker (SAF): RBPMS mRNA
Genes: RBPMS; HERMES
Study 33484628 — Surrogate Endpoint (SUR): Blood pressure
Study 33888102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 33902656 — Surrogate Endpoint (SUR): Blood pressure
Study 33220297 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 34119499 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 34119499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34119499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33491424 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34002562 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 32833918 — Surrogate Endpoint (SUR): Blood pressure
Study 34210209 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34410847 — Surrogate Endpoint (SUR): Blood pressure
Study 32365849 — Surrogate Endpoint (SUR): Blood pressure
Study 32365849 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33310488 — Surrogate Endpoint (SUR): Blood pressure
Study 35777494 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 32089456 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 32089456 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32089456 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36397083 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 35610265 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 36008352 — Surrogate Endpoint (SUR): Serum creatinine
Study 32470924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33514869 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33514869 — Predictive Biomarker (PRD): COG2 mRNA
Genes: COG2; LDLC
Study 35922444 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 35922444 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 35922444 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 35922444 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 35922444 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 35922444 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 35922444 — Predictive Biomarker (PRD): PTPN11 mRNA
Genes: PTPN11; PTP2C; SHPTP2
Study 35922444 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 35922444 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33534382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33534382 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 33534382 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 33077275 — Surrogate Endpoint (SUR): Blood pressure
Study 33169661 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33197654 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33197654 — Safety Biomarker (SAF): BDNF
Study 32183895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32183895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32485778 — Surrogate Endpoint (SUR): Blood pressure
Study 32485778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34936057 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35357105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35357105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35357105 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 35357105 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 35357105 — Safety Biomarker (SAF): Interleukin 12
Study 34330608 — Predictive Biomarker (PRD): ITK mRNA
Genes: ITK; EMT; LYK
Study 33580673 — Predictive Biomarker (PRD): MYH6 mRNA
Genes: MYH6; MYHCA
Study 33580673 — Predictive Biomarker (PRD): PITX2 mRNA
Genes: PITX2; ARP1; RGS; RIEG; RIEG1
Study 33580673 — Predictive Biomarker (PRD): ZFHX3 mRNA
Genes: ZFHX3; ATBF1; C16orf47
Study 33580673 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 33580673 — Predictive Biomarker (PRD): CCDC141 mRNA
Genes: CCDC141; CAMDI
Study 33580673 — Predictive Biomarker (PRD): KRT8 mRNA
Genes: KRT8; CYK8
Study 34032731 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 34032731 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34032731 — Surrogate Endpoint (SUR): Blood pressure
Study 32783667 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 33049411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33049411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35020796 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35020796 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35020796 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35020796 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36286922 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33770392 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32040523 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study 32769878 — Surrogate Endpoint (SUR): Blood pressure
Study 36357159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36357159 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36357159 — Safety Biomarker (SAF): Platelet to lymphocyte
Study 33722866 — Surrogate Endpoint (SUR): Blood pressure
Study 33722866 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33722866 — Surrogate Endpoint (SUR): Serum creatinine
Study 32325257 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 32096571 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32096571 — Surrogate Endpoint (SUR): Blood pressure
Study 34028790 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 35500316 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35500316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35500316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35500316 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35500316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33246489 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP