TrialPanorama/TrialPanorama-database huggingface dataset:
Study 34016350 — Predictive Biomarker (PRD): PRDX3 mRNA
Genes: PRDX3; AOP1
Study 32160043 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 32160043 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 33827450 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32799403 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 34432008 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34432008 — Surrogate Endpoint (SUR): Bone mineral density
Study 32055041 — Surrogate Endpoint (SUR): Bone mineral density
Study 35616226 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32614141 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 36410799 — Surrogate Endpoint (SUR): Blood pressure
Study 33825412 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33825412 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 34097062 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 34097062 — Surrogate Endpoint (SUR): Blood pressure
Study 35750094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32293362 — Surrogate Endpoint (SUR): Pathological complete response
Study 36147247 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32054537 — Surrogate Endpoint (SUR): Blood pressure
Study 33769293 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 32089006 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32089006 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33076885 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36427629 — Surrogate Endpoint (SUR): Blood pressure
Study 33161162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33161162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34435440 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33026755 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 33026755 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 33440046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33413727 — Surrogate Endpoint (SUR): Blood pressure
Study 35333140 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 34387126 — Surrogate Endpoint (SUR): Blood pressure
Study 36253171 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 34018006 — Surrogate Endpoint (SUR): Bone mineral density
Study 32170761 — Predictive Biomarker (PRD): ELF4 mRNA
Genes: ELF4; ELFR; MEF
Study 32170761 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 35373274 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 36323462 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34923163 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 35568194 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35568194 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32596882 — Surrogate Endpoint (SUR): Blood pressure
Study 32458495 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 32458495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32458495 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 32493411 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 32493411 — Surrogate Endpoint (SUR): Bone mineral density
Study 34146697 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 32985902 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 35367015 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 35181293 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 34905069 — Predictive Biomarker (PRD): SLC6A7 mRNA
Genes: SLC6A7; PROT
Study 32345077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32154928 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32154928 — Monitoring Biomarker (MOI): Angiopoietin 1 receptor
Genes: TEK; TIE2; VMCM; VMCM1
Study 32154928 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33766084 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 33766084 — Surrogate Endpoint (SUR): Blood pressure
Study 33151634 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 32991776 — Surrogate Endpoint (SUR): Serum creatinine
Study 34697566 — Surrogate Endpoint (SUR): Blood pressure
Study 35152918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 32206772 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 32206772 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32206772 — Predictive Biomarker (PRD): BIRC3 mRNA
Genes: BIRC3; API2; MIHC; RNF49
Study 33735404 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 33735404 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33735404 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32659755 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32659755 — Surrogate Endpoint (SUR): Serum creatinine
Study 34554379 — Predictive Biomarker (PRD): BSG mRNA
Genes: BSG; UNQ6505/PRO21383
Study 35863559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33845881 — Safety Biomarker (SAF): Reactive oxygen species
Study 33845881 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34847228 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 34847228 — Predictive Biomarker (PRD): Liver iron
Study 33004724 — Surrogate Endpoint (SUR): Blood pressure
Study 36001383 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32740081 — Predictive Biomarker (PRD): TNNT1 mRNA
Genes: TNNT1; TNT
Study 34266574 — Surrogate Endpoint (SUR): Blood pressure
Study 34120186 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 34120186 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34120186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33645069 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 32305457 — Predictive Biomarker (PRD): LRRFIP1 mRNA
Genes: LRRFIP1; GCF2; TRIP
Study 2000318910 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 36207530 — Surrogate Endpoint (SUR): Blood pressure
Study 33492457 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 34042572 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 33863383 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 33863383 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 36398114 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 36398114 — Surrogate Endpoint (SUR): Bone mineral density
Study 34058071 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 34058071 — Pharmacodynamic Biomarker (PDY): Dermal blood flow
Study 32332636 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 32986748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35617987 — Predictive Biomarker (PRD): HPN mRNA
Genes: HPN; TMPRSS1
Study 34137329 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 33423966 — Predictive Biomarker (PRD): CDCA7L mRNA
Genes: CDCA7L; HR1; JPO2; R1
Study 34799265 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 36416543 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 32618037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32857471 — Surrogate Endpoint (SUR): Serum potassium
Study 35293348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34468726 — Predictive Biomarker (PRD): KCNK17 mRNA
Genes: KCNK17; TALK2; TASK4; UNQ5816/PRO19634
Study 35709685 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 33098441 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32406998 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 36299538 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34658781 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 32917359 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 33186174 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 32965623 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32965623 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 32965623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32560181 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 32560181 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 35272404 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34702773 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 34702773 — Predictive Biomarker (PRD): FCGR1A mRNA
Genes: FCGR1A; FCG1; FCGR1; IGFR1
Study 34702773 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study 35898448 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 35898448 — Surrogate Endpoint (SUR): Bone mineral density
Study 32853242 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 33740332 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32817282 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 32817282 — Predictive Biomarker (PRD): NFKBIA mRNA
Genes: NFKBIA; IKBA; MAD3; NFKBI
Study 32767163 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35634285 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35634285 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 35634285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36031855 — Surrogate Endpoint (SUR): Blood pressure
Study 32646282 — Surrogate Endpoint (SUR): Blood pressure
Study 35405088 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35405088 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35405088 — Predictive Biomarker (PRD): Hormone receptor
Study 35405088 — Surrogate Endpoint (SUR): Pathological complete response
Study 33711991 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 33711991 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 33711991 — Predictive Biomarker (PRD): CXCL16 mRNA
Genes: CXCL16; SCYB16; SRPSOX; UNQ2759/PRO6714
Study 33711991 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 32814717 — Predictive Biomarker (PRD): PITX2 mRNA
Genes: PITX2; ARP1; RGS; RIEG; RIEG1
Study 34508594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36051928 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PRND mRNA
Genes: PRND; DPL; UNQ1830/PRO3443
Study 34897099 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study 33789909 — Surrogate Endpoint (SUR): Blood pressure
Study 32067585 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33421309 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 36294463 — Surrogate Endpoint (SUR): Blood pressure
Study 32698457 — Surrogate Endpoint (SUR): Blood pressure
Study 34014615 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 33526730 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33526730 — Surrogate Endpoint (SUR): Blood pressure
Study 35796876 — Surrogate Endpoint (SUR): Blood pressure
Study 32434467 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 32206987 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32206987 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32206987 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34465810 — Predictive Biomarker (PRD): SMOX mRNA
Genes: SMOX; C20orf16; SMO; UNQ3039/PRO9854
Study 33302685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33302685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33302685 — Surrogate Endpoint (SUR): Blood pressure
Study 34225270 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 32198596 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 32198596 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 33801767 — Surrogate Endpoint (SUR): Blood pressure
Study 34864766 — Surrogate Endpoint (SUR): Bone mineral density
Study 33112481 — Predictive Biomarker (PRD): REG1B mRNA
Genes: REG1B; PSPS2; REGL
Study 32482611 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 35050952 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32842644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34841615 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 34841615 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 34841615 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34735643 — Surrogate Endpoint (SUR): Blood pressure
Study 32596729 — Surrogate Endpoint (SUR): Blood pressure
Study 34160347 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 33066857 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 33066857 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 32473678 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 2012036615 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2012036615 — Surrogate Endpoint (SUR): Blood pressure
Study 2012036615 — Surrogate Endpoint (SUR): Serum creatinine
Study 34035100 — Predictive Biomarker (PRD): NUBP1 mRNA
Genes: NUBP1; NBP; NBP1
Study 36378768 — Surrogate Endpoint (SUR): Blood pressure
Study 35852035 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 35852035 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35135037 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 35135037 — Surrogate Endpoint (SUR): Blood pressure
Study 35473780 — Safety Biomarker (SAF): Interleukin 1
Study 32919280 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 32919280 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 34582653 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35576286 — Surrogate Endpoint (SUR): Blood pressure
Study 33940347 — Predictive Biomarker (PRD): Microsatellite instability
Study 34082792 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 36345809 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36130612 — Surrogate Endpoint (SUR): Blood pressure
Study 35575766 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 32379982 — Surrogate Endpoint (SUR): Blood pressure
Study 34536714 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 34028012 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 34028012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32503652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32503652 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35949922 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33592011 — Surrogate Endpoint (SUR): Blood pressure
Study 32416072 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 35377723 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34505019 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 33861738 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 33861738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33861738 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 33861738 — Predictive Biomarker (PRD): IL37 mRNA
Genes: IL37; FIL1Z; IL1F7; IL1H4; IL1RP1
Study 32434362 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 33992812 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33558193 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33481251 — Surrogate Endpoint (SUR): Blood pressure
Study 34290294 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FLNA mRNA
Genes: FLNA; FLN; FLN1
Study 34290294 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 34290294 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 34590570 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 36220354 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 33856337 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 32103280 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 35035537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 615709281 — Surrogate Endpoint (SUR): Plasma ammonia
Study 34464358 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34085881 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32529788 — Predictive Biomarker (PRD): HBEGF mRNA
Genes: HBEGF; DTR; DTS; HEGFL
Study 36285551 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 32701239 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 34924360 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35713772 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35241098 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34247263 — Surrogate Endpoint (SUR): Bone mineral density
Study 35180190 — Safety Biomarker (SAF): Interleukin 1
Study 32357133 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 36216962 — Surrogate Endpoint (SUR): Bone mineral density
Study 35501751 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 616117228 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 616117228 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 36062851 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33517316 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35286033 — Safety Biomarker (SAF): Reactive oxygen species
Study 34902765 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34902765 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34902765 — Predictive Biomarker (PRD): Hormone receptor
Study 35079806 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 35079806 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33408462 — Surrogate Endpoint (SUR): Blood pressure
Study 32928328 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32928328 — Surrogate Endpoint (SUR): Blood pressure
Study 33927176 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 33927176 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 33927176 — Surrogate Endpoint (SUR): Serum creatinine
Study 35332042 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 35472112 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 33799486 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 33965556 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33965556 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 33965556 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33965556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33965556 — Safety Biomarker (SAF): BDNF
Study 33965556 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35783486 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34237271 — Monitoring Biomarker (MOI): HBV DNA
Study 32876804 — Surrogate Endpoint (SUR): Blood pressure
Study 32876804 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32876804 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35904638 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35904638 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33159256 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32862697 — Surrogate Endpoint (SUR): Blood pressure
Study 32448171 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 32931308 — Safety Biomarker (SAF): Hyaluronic acid
Study 34607479 — Predictive Biomarker (PRD): ITIH4 mRNA
Genes: ITIH4; IHRP; ITIHL1; PK120; PRO1851