TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35331663 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33191765 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 33191765 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 33514384 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34798037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34314727 — Predictive Biomarker (PRD): IDE mRNA
Genes: IDE
Study 33004127 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 32916609 — Surrogate Endpoint (SUR): Blood pressure
Study 35881907 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 35881907 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35202353 — Predictive Biomarker (PRD): MOXD1 mRNA
Genes: MOXD1; MOX; UNQ2493/PRO5780
Study 34219000 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33596340 — Surrogate Endpoint (SUR): Blood pressure
Study 32336008 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32336008 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33688714 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32011502 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 32011502 — Surrogate Endpoint (SUR): Blood pressure
Study 36109083 — Surrogate Endpoint (SUR): Blood pressure
Study 33409923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33409923 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 36293881 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 33758941 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 33758941 — Predictive Biomarker (PRD): TMPRSS6 mRNA
Genes: TMPRSS6; UNQ354/PRO618
Study 33758941 — Predictive Biomarker (PRD): TFR2 mRNA
Genes: TFR2
Study 33758941 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 32829945 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 32829945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32829945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35049137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35049137 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 35049137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35536382 — Predictive Biomarker (PRD): FBXO8 mRNA
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 35536382 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35301662 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 32588036 — Surrogate Endpoint (SUR): Blood pressure
Study 34512931 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 32316978 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 32316978 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 35314767 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 32172522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33455975 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 35378948 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35378948 — Safety Biomarker (SAF): Interleukin 1
Study 35378948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35378948 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35468660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33873029 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 33873029 — Predictive Biomarker (PRD): UGT2B10 mRNA
Genes: UGT2B10
Study 33873029 — Predictive Biomarker (PRD): UGT2B17 mRNA
Genes: UGT2B17
Study 36339187 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 32034581 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34496450 — Surrogate Endpoint (SUR): Blood pressure
Study 35763247 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 35763247 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 33413428 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34378365 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 35333783 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 35333783 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35333783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32307430 — Surrogate Endpoint (SUR): Blood pressure
Study 32991818 — Safety Biomarker (SAF): Bacteroidetes phylum
Study 33438713 — Predictive Biomarker (PRD): DNM1 mRNA
Genes: DNM1; DNM
Study 33573687 — Surrogate Endpoint (SUR): Blood pressure
Study 34637450 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33866430 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32609313 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32609313 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32609313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34302758 — Predictive Biomarker (PRD): IL33 mRNA
Genes: IL33; C9orf26; IL1F11; NFHEV
Study 34302758 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 32356023 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 32356023 — Predictive Biomarker (PRD): ADORA2A mRNA
Genes: ADORA2A; ADORA2
Study 32323557 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 33632715 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 33632715 — Predictive Biomarker (PRD): SLC35A2 mRNA
Genes: SLC35A2; UGALT; UGT; UGTL
Study 32155773 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 32173650 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 32173650 — Predictive Biomarker (PRD): CHIT1 mRNA
Genes: CHIT1
Study 32777055 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 35191898 — Surrogate Endpoint (SUR): Bone mineral density
Study 36044708 — Monitoring Biomarker (MOI): miR-195-5p
Genes: MIR195
Study 33705205 — Predictive Biomarker (PRD): WEE1 mRNA
Genes: WEE1
Study 32954832 — Surrogate Endpoint (SUR): Blood pressure
Study 32542854 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 32542854 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34490460 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32054426 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 32539426 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 33125753 — Surrogate Endpoint (SUR): Blood pressure
Study 34299814 — Surrogate Endpoint (SUR): Blood pressure
Study 36229087 — Surrogate Endpoint (SUR): Blood pressure
Study 36229087 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34020931 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32268604 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32268604 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 33146791 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 33883195 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33544066 — Surrogate Endpoint (SUR): Blood pressure
Study 32636128 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32342247 — Surrogate Endpoint (SUR): Blood pressure
Study 32865062 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 32863246 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 33250205 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 33250205 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 34836079 — Predictive Biomarker (PRD): SIRT3 mRNA
Genes: SIRT3; SIR2L3
Study 34836079 — Predictive Biomarker (PRD): SIRT5 mRNA
Genes: SIRT5; SIR2L5
Study 34102553 — Surrogate Endpoint (SUR): Blood pressure
Study 33109273 — Surrogate Endpoint (SUR): Blood pressure
Study 34088883 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 35356064 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 35356064 — Safety Biomarker (SAF): Platelet to lymphocyte
Study 33547300 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33547300 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33096207 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35340062 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 35340062 — Surrogate Endpoint (SUR): Bone mineral density
Study 34109595 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 34109595 — Safety Biomarker (SAF): Platelet to lymphocyte
Study 34213683 — Predictive Biomarker (PRD): FBXO8 mRNA
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 32960886 — Surrogate Endpoint (SUR): Blood pressure
Study 33082420 — Surrogate Endpoint (SUR): Serum creatinine
Study 35954510 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 33653805 — Predictive Biomarker (PRD): ORMDL3 mRNA
Genes: ORMDL3
Study 32239190 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 32239190 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32239190 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32113756 — Safety Biomarker (SAF): Bacteroidetes phylum
Study 36311789 — Predictive Biomarker (PRD): LAMB3 mRNA
Genes: LAMB3; LAMNB1
Study 36311789 — Predictive Biomarker (PRD): Laminin subunit alpha-3
Genes: LAMA3; LAMNA
Study 36311789 — Predictive Biomarker (PRD): ITGB6 mRNA
Genes: ITGB6
Study 36311789 — Predictive Biomarker (PRD): ITGB4 mRNA
Genes: ITGB4
Study 36311789 — Predictive Biomarker (PRD): ITGA2 mRNA
Genes: ITGA2; CD49B
Study 36311789 — Predictive Biomarker (PRD): LAMC2 mRNA
Genes: LAMC2; LAMB2T; LAMNB2
Study 36311789 — Predictive Biomarker (PRD): COL11A1 mRNA
Genes: COL11A1; COLL6
Study 32858844 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32858844 — Predictive Biomarker (PRD): NFKB1 mRNA
Genes: NFKB1
Study 32858844 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36167599 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 33958669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33958669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33958669 — Safety Biomarker (SAF): IL-6 and IL-10
Study 36402355 — Surrogate Endpoint (SUR): Blood pressure
Study 33764567 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35644332 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 616774593 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35704475 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 32787879 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32787879 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 32787879 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32787879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32787879 — Surrogate Endpoint (SUR): Blood pressure
Study 33849118 — Monitoring Biomarker (MOI): Procalcitonin
Study 33159533 — Surrogate Endpoint (SUR): Bone mineral density
Study 33956804 — Predictive Biomarker (PRD): LRP1 mRNA
Genes: LRP1; A2MR; APR
Study 35277845 — Surrogate Endpoint (SUR): Sperm parameters
Study 35507955 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35507955 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33920725 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32377302 — Predictive Biomarker (PRD): SELENOP mRNA
Genes: SELENOP; SELP; SEPP1
Study 32377302 — Surrogate Endpoint (SUR): Blood pressure
Study 32377302 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32647353 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 33084081 — Surrogate Endpoint (SUR): Blood pressure
Study 35502891 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32196636 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 33183320 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 35867209 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 33998561 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 33998561 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 34491649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34669586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34669586 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34669586 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34882193 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 32311845 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 36422809 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 36422809 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 33065133 — Predictive Biomarker (PRD): HCG22 mRNA
Genes: HCG22; G2; PBMUCL2
Study 616062701 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 32644148 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32644148 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33302116 — Surrogate Endpoint (SUR): Blood pressure
Study 36042056 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32636122 — Surrogate Endpoint (SUR): Blood pressure
Study 32443961 — Surrogate Endpoint (SUR): Blood pressure
Study 33641656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33641656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36228639 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35181556 — Surrogate Endpoint (SUR): Serum creatinine
Study 33037080 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 33037080 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 33037080 — Predictive Biomarker (PRD): STAT2 mRNA
Genes: STAT2
Study 33037080 — Predictive Biomarker (PRD): STAT4 mRNA
Genes: STAT4
Study 32605106 — Surrogate Endpoint (SUR): Blood pressure
Study 35976361 — Surrogate Endpoint (SUR): Blood pressure
Study 34775413 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 33991802 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32152202 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 32152202 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 35212104 — Surrogate Endpoint (SUR): Blood pressure
Study 34895218 — Safety Biomarker (SAF): APC
Genes: DP2; DP3; DP2.5; PPP1R46
Study 32448894 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35854638 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 33663274 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32868525 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 32868525 — Predictive Biomarker (PRD): Microsatellite instability
Study 34360284 — Predictive Biomarker (PRD): FGFR1
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 36064434 — Pharmacodynamic Biomarker (PDY): Spinal and brainstem neurophysiological measures
Study 33834318 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35026498 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34427177 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 35238796 — Surrogate Endpoint (SUR): Blood pressure
Study 35143902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35143902 — Monitoring Biomarker (MOI): Procalcitonin
Study 33715788 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 32929337 — Safety Biomarker (SAF): Reactive oxygen species
Study 34439234 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32584511 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34114407 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 34114407 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 34114407 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 34114407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34114407 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 34114407 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 34114407 — Safety Biomarker (SAF): Interleukin 12
Study 36419383 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 35883143 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 33882774 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35926833 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33196511 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33196511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33050072 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 32303884 — Surrogate Endpoint (SUR): Blood pressure
Study 35104848 — Predictive Biomarker (PRD): LANCL2 mRNA
Genes: LANCL2; GPR69B; TASP
Study 35104848 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33050924 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33050924 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 33050924 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 32838661 — Surrogate Endpoint (SUR): Serum creatinine
Study 32838661 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 32897035 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35634513 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 35634513 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35634513 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 35634513 — Safety Biomarker (SAF): Reactive oxygen species
Study 35237860 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 32339978 — Predictive Biomarker (PRD): UQCRC1 mRNA
Genes: UQCRC1
Study 32339978 — Predictive Biomarker (PRD): MXRA5 mRNA
Genes: MXRA5
Study 32396266 — Predictive Biomarker (PRD): CYP4V2 mRNA
Genes: CYP4V2
Study 32316994 — Surrogate Endpoint (SUR): Serum creatinine
Study 32838710 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 35836948 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 33256506 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 32335402 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 32335402 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35241032 — Surrogate Endpoint (SUR): Blood pressure
Study 34621181 — Surrogate Endpoint (SUR): Blood pressure
Study 34621181 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36319585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33798493 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33534773 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32711058 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36401615 — Predictive Biomarker (PRD): ZBTB7A mRNA
Genes: ZBTB7A; FBI1; LRF; ZBTB7; ZNF857A
Study 34961942 — Safety Biomarker (SAF): Hyaluronic acid
Study 34213868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34213868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34626891 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study 32548702 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33130570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33130570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33130570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33654240 — Surrogate Endpoint (SUR): Blood pressure
Study 32909660 — Predictive Biomarker (PRD): CCL26 mRNA
Genes: CCL26; SCYA26; UNQ216/PRO242
Study 32909660 — Predictive Biomarker (PRD): SERPINB2 mRNA
Genes: SERPINB2; PAI2; PLANH2
Study 32909660 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 32909660 — Predictive Biomarker (PRD): Exhaled nitric oxide