TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT06192888 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05674058 — Predictive Biomarker (PRD): ABCA4 mRNA
Genes: ABCA4; ABCR
Study NCT06078852 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT05886036 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT05886036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06788041 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06786299 — Predictive Biomarker (PRD): CD84 mRNA
Genes: CD84; SLAMF5
Study NCT06476717 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05218005 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT06782932 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06782932 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT05569642 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06784310 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06784310 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06784869 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT05645640 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00001116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00001116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00001116 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04713631 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06670742 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT06272487 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06099769 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT06099769 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06509906 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study NCT06775912 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06777329 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06776848 — Predictive Biomarker (PRD): TBR1 mRNA
Genes: TBR1
Study NCT06777082 — Predictive Biomarker (PRD): RPL8 mRNA
Genes: RPL8
Study NCT06776510 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT04939051 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT05947344 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT04734067 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05982496 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT06786208 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06786910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06785181 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05572957 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT06775236 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06782672 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05579327 — Predictive Biomarker (PRD): SLC16A2 mRNA
Genes: SLC16A2; MCT7; MCT8; XPCT
Study NCT06786676 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06787118 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04625647 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06784687 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06787612 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT05888701 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study NCT06787560 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT06056583 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT03896516 — Predictive Biomarker (PRD): MBOAT4 mRNA
Genes: MBOAT4; GOAT; OACT4; FKSG89
Study NCT03896516 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05254184 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06441747 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06785662 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT06530914 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05330195 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06784219 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT06784349 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study NCT06784349 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT06784349 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06784349 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06783309 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study NCT06727383 — Predictive Biomarker (PRD): KLRD1 mRNA
Genes: KLRD1; CD94
Study NCT06727383 — Predictive Biomarker (PRD): KLRC1 mRNA
Genes: KLRC1; NKG2A
Study NCT06727383 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study NCT06727383 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT06727383 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study NCT06782061 — Predictive Biomarker (PRD): NOD2 mRNA
Genes: NOD2; CARD15; IBD1
Study NCT06784583 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06725940 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): GZMB mRNA
Genes: GZMB; CGL1; CSPB; CTLA1; GRB
Study NCT06456463 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT05160480 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05160480 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT05159375 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06068049 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06435429 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06541847 — Predictive Biomarker (PRD): HLX mRNA
Genes: HLX; HLX1
Study NCT06541847 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT06333340 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06475755 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05235542 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study NCT05169580 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06013033 — Predictive Biomarker (PRD): GSDMD mRNA
Genes: GSDMD; DFNA5L; GSDMDC1; FKSG10
Study NCT05218174 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06783270 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06787989 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06787989 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04897438 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT06417801 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06385678 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05170399 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05198674 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06635707 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05002569 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study NCT04441047 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06373159 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05500742 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT06557733 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT06164587 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05524883 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06091254 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT06784089 — Safety Biomarker (SAF): Prognostic nutrition index
Study NCT06782646 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT06785415 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT06786533 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT06782477 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study NCT05917158 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05697146 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05697146 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05187182 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05487261 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT05547360 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05362903 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06092879 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT05994235 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study NCT06557265 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05487235 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06635902 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06636565 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06143293 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05889988 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04579224 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04579224 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05147350 — Predictive Biomarker (PRD): PKMYT1 mRNA
Genes: PKMYT1; MYT1
Study NCT06487845 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05677997 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04647526 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05938803 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05082246 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04714892 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05495932 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT05050461 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05050461 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT05503108 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05503108 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05503108 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05674019 — Predictive Biomarker (PRD): ADGRG1 mRNA
Genes: ADGRG1; GPR56; TM7LN4; TM7XN1; UNQ540/PRO1083
Study NCT05137444 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06606366 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06677957 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT06110442 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06538038 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06538038 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05254002 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06137170 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06776978 — Safety Biomarker (SAF): Coagulation factor Va
Genes: F5
Study NCT06775470 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04563195 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT06496568 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT06113640 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study NCT05584072 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06419023 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05330819 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05330819 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT06364371 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT04704466 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04850469 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05820724 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06725524 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT06726538 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT06725095 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT06726161 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT05671406 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06335303 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04851613 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04851613 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04851613 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06439277 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05767359 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05306340 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05306340 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05306340 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05199688 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT05975073 — Predictive Biomarker (PRD): MTAP mRNA
Genes: MTAP; MSAP
Study NCT05701696 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT06160310 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT06177106 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05483075 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05734560 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT05708456 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06504732 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05526248 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT06414889 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT06414889 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study NCT06123338 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06316843 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06169254 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06635447 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06635447 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06635447 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06635447 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06091020 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT05735587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05735587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06444880 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT05523050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05523050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05331144 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05331144 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06175637 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT06029920 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06029920 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06029920 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06029920 — Safety Biomarker (SAF): BDNF
Study NCT05359211 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06178549 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04690816 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05899127 — Predictive Biomarker (PRD): PNOC mRNA
Genes: PNOC; OFQ
Study NCT05117762 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02176135 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06364410 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05511701 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06311214 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05953896 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05502354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05573893 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05573893 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06533579 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06581861 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT05939869 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04829604 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06467461 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT06002789 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04286373 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04286373 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study NCT04486352 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT06441682 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT06395038 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT06395038 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05633472 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT06113055 — Predictive Biomarker (PRD): SPTLC2 mRNA
Genes: SPTLC2; KIAA0526; LCB2
Study NCT05427669 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04797247 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04774068 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT06219941 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT06566456 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04750473 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05401630 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05115110 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT05945927 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05659368 — Predictive Biomarker (PRD): WFS1 mRNA
Genes: WFS1
Study NCT05659368 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT04659616 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT06555744 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT04442061 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT06476665 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT06645470 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05683834 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05109624 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06097663 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study NCT06097663 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study NCT06390995 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT06210776 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03590821 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05509595 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT05509595 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT05509595 — Surrogate Endpoint (SUR): Serum phosphate
Study NCT05530070 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04839224 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05785624 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05938075 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04899349 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04899349 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT04899349 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06235151 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05664880 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT05434949 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04891380 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05967299 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT05840211 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05840211 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05840211 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05840211 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04961996 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL