TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33049412 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 35586118 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34345377 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 35115825 — Surrogate Endpoint (SUR): Blood pressure
Study 32989795 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 33407788 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35370460 — Surrogate Endpoint (SUR): Blood pressure
Study 34225535 — Surrogate Endpoint (SUR): Blood pressure
Study 33277982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33277982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35703882 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35703882 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 33854050 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 33434094 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 33888367 — Surrogate Endpoint (SUR): Blood pressure
Study 35771961 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33040810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33040810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32011301 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 32011301 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 32011301 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 32012411 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34971040 — Predictive Biomarker (PRD): AMIGO1 mRNA
Genes: AMIGO1; ALI2; AMIGO; KIAA1163
Study 32266572 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 33565237 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34332584 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 34332584 — Surrogate Endpoint (SUR): Blood pressure
Study 33547487 — Surrogate Endpoint (SUR): Bone mineral density
Study 35775723 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33043353 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 34256031 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 34256031 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32359153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35953719 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 35953719 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35953719 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32051386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35114340 — Surrogate Endpoint (SUR): Serum triglycerides
Study 35114340 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35114340 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32380449 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study 35524415 — Surrogate Endpoint (SUR): Blood pressure
Study 34463434 — Surrogate Endpoint (SUR): Complete renal response
Study 35202553 — Predictive Biomarker (PRD): SULT1A3 mRNA
Genes: SULT1A3; STM
Study 33592607 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 35490599 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 33455792 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33567127 — Surrogate Endpoint (SUR): Bone mineral density
Study 32150085 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33622079 — Safety Biomarker (SAF): Reactive oxygen species
Study 35614518 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 35788622 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35085503 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 35085503 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34325186 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34598813 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 32119714 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 35347281 — Predictive Biomarker (PRD): COL7A1 mRNA
Genes: COL7A1
Study 35347281 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 33508990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34476629 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 33975039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33975039 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32004709 — Surrogate Endpoint (SUR): Blood pressure
Study 33958657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35217575 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study 34518266 — Surrogate Endpoint (SUR): Blood pressure
Study 32940187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32940187 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 33683019 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35036430 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33908729 — Surrogate Endpoint (SUR): Blood pressure
Study 35959357 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35959357 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 34103634 — Predictive Biomarker (PRD): GSDMB mRNA
Genes: GSDMB; GSDML; PP4052; PRO2521
Study 34103634 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 34103634 — Predictive Biomarker (PRD): CLEC16A mRNA
Genes: CLEC16A; KIAA0350
Study 34103634 — Predictive Biomarker (PRD): Interleukin 4 receptor alpha
Genes: IL4R; IL4RA; 582J2.1
Study 34103634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34103634 — Predictive Biomarker (PRD): TNFSF4 mRNA
Genes: TNFSF4; TXGP1
Study 32674048 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 35657955 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33934389 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32949140 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 33412997 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 33710385 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 32286711 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35291433 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33636418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33636418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34639600 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 32323706 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32323706 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 32323706 — Surrogate Endpoint (SUR): Blood pressure
Study 33736696 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33782092 — Surrogate Endpoint (SUR): Blood pressure
Study 32100499 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35914911 — Safety Biomarker (SAF): BDNF
Study 35914911 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32747302 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 32887850 — Surrogate Endpoint (SUR): Blood pressure
Study 32112114 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34090775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32711393 — Surrogate Endpoint (SUR): Blood pressure
Study 34099328 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32419935 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 32419935 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35191746 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33705547 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 33705547 — Predictive Biomarker (PRD): JMJD1C mRNA
Genes: JMJD1C; JHDM2C; KIAA1380; TRIP8
Study 33880495 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 32352877 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 33038227 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 35066950 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35066950 — Surrogate Endpoint (SUR): Blood pressure
Study 35066950 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 35066950 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33158717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33158717 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33161148 — Surrogate Endpoint (SUR): Blood pressure
Study 35189953 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 35189953 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 32167131 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 32167131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32718816 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32753547 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32753547 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 32753547 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 32753547 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 32753547 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32753547 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 36495282 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 32895339 — Surrogate Endpoint (SUR): Blood pressure
Study 32460904 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 32077470 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 33431616 — Surrogate Endpoint (SUR): Blood pressure
Study 36143083 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 36143083 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 36143083 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 33221914 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 32816626 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35306584 — Surrogate Endpoint (SUR): Blood pressure
Study 34218922 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34135190 — Surrogate Endpoint (SUR): Blood pressure
Study 35413533 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 36495356 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 36495356 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 32839833 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33000503 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 34087418 — Surrogate Endpoint (SUR): Blood pressure
Study 33087164 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34406656 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 33189630 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36235676 — Surrogate Endpoint (SUR): Blood pressure
Study 36235676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36235676 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34001723 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 34001723 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 34001723 — Surrogate Endpoint (SUR): Blood pressure
Study 34001723 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34750747 — Surrogate Endpoint (SUR): Serum creatinine
Study 32348168 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32348168 — Surrogate Endpoint (SUR): Blood pressure
Study 34918875 — Predictive Biomarker (PRD): MPZ mRNA
Genes: MPZ
Study 34918875 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 34918875 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 34918875 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 34918875 — Safety Biomarker (SAF): DRD2
Study 35145122 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 34623746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34470300 — Surrogate Endpoint (SUR): Blood pressure
Study 34863618 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36159932 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 36159932 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34863138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35638415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34614146 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 34414904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35872963 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 35872963 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35751161 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 33189262 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 33189262 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 32947569 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33423544 — Surrogate Endpoint (SUR): Blood pressure
Study 36090567 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 35930838 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35930838 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 624995555 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 32354736 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 32354736 — Predictive Biomarker (PRD): CALR mRNA
Genes: CALR; CRTC
Study 32354736 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 34865332 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 35045869 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 34377158 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34377158 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33112779 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32380271 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32380271 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36181104 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33927413 — Predictive Biomarker (PRD): PDE4D mRNA
Genes: PDE4D; DPDE3
Study 32899959 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 35010953 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35010953 — Safety Biomarker (SAF): Reactive oxygen species
Study 35673488 — Surrogate Endpoint (SUR): Blood pressure
Study 35673488 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35673488 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32882310 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 32882310 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 33208345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34166370 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 32051084 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 32632732 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 33236669 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33914047 — Surrogate Endpoint (SUR): Blood pressure
Study 32279446 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 33602798 — Predictive Biomarker (PRD): IVL mRNA
Genes: IVL
Study 32227613 — Surrogate Endpoint (SUR): Blood pressure
Study 35727586 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 34531495 — Predictive Biomarker (PRD): Activated leukocyte cell adhesionmolecule
Genes: ALCAM; MEMD
Study 34531495 — Predictive Biomarker (PRD): RIPOR2 mRNA
Genes: RIPOR2; C6orf32; DIFF48; FAM65B; KIAA0386; PL48
Study 34531495 — Predictive Biomarker (PRD): MOCOS mRNA
Genes: MOCOS
Study 34230018 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 33586615 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 33586615 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 33413034 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33413034 — Surrogate Endpoint (SUR): Blood pressure
Study 35043012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33953794 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 33953794 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 35931957 — Predictive Biomarker (PRD): NELFCD mRNA
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 32859477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35897358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35897358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35897358 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 33143361 — Predictive Biomarker (PRD): CLNK mRNA
Genes: CLNK; MIST
Study 32554833 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32554833 — Safety Biomarker (SAF): BDNF
Study 33965414 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 32108437 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 34543256 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 34506563 — Safety Biomarker (SAF): Hyaluronic acid
Study 33380579 — Surrogate Endpoint (SUR): Blood pressure
Study 34237810 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34245857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34245857 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 34245857 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 34986394 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35959348 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35959348 — Surrogate Endpoint (SUR): Blood pressure
Study 33991999 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 34853915 — Surrogate Endpoint (SUR): Blood pressure
Study 32006028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35961278 — Safety Biomarker (SAF): Vascular endothelial cadherin
Genes: CDH5
Study 35961278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 34952856 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33025051 — Surrogate Endpoint (SUR): Blood pressure
Study 36151017 — Surrogate Endpoint (SUR): Pathological complete response
Study 33966345 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 33988708 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study 32959590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32959590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32959590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33168657 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 33168657 — Predictive Biomarker (PRD): Hormone receptor
Study 32519782 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 33835939 — Surrogate Endpoint (SUR): Bone mineral density
Study 33835939 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 33835939 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 34564706 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 35533496 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35533496 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35533496 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 36335517 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32350686 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS