TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35995769 — Predictive Biomarker (PRD): HIC1 mRNA
Genes: HIC1; ZBTB29
Study 35995769 — Predictive Biomarker (PRD): CYP26A1 mRNA
Genes: CYP26A1; CYP26; P450RAI1
Study 35995769 — Predictive Biomarker (PRD): GBP4 mRNA
Genes: GBP4
Study 35995769 — Predictive Biomarker (PRD): LYZ mRNA
Genes: LYZ; LZM
Study 32940404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32940404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32940404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32917495 — Surrogate Endpoint (SUR): Blood pressure
Study 32510737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35172859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32776101 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 34416469 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34022474 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34022474 — Safety Biomarker (SAF): BDNF
Study 35067237 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34014249 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34014249 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34014249 — Predictive Biomarker (PRD): Hormone receptor
Study 35329366 — Surrogate Endpoint (SUR): Blood pressure
Study 35617826 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32470703 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32470703 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32333510 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 35018724 — Surrogate Endpoint (SUR): Probing pocket depth
Study 35331534 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 35331534 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36383882 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 35405335 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 36112790 — Surrogate Endpoint (SUR): Blood pressure
Study 34602038 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 32065946 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32065946 — Safety Biomarker (SAF): BDNF
Study 32970104 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 34718548 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 32394652 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 32394652 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 33410359 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 36320214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34711947 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 33094728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33094728 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33094728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33094728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33094728 — Surrogate Endpoint (SUR): Serum uric acid
Study 35113605 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33984786 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 32357081 — Surrogate Endpoint (SUR): Blood pressure
Study 33031169 — Surrogate Endpoint (SUR): Blood pressure
Study 32075842 — Surrogate Endpoint (SUR): Blood pressure
Study 33210382 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 32329438 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 32329438 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32329438 — Surrogate Endpoint (SUR): Blood pressure
Study 32329438 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35970940 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 35229621 — Surrogate Endpoint (SUR): Blood pressure
Study 32176107 — Predictive Biomarker (PRD): ELP1 mRNA
Genes: ELP1; IKAP; IKBKAP
Study 32176107 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33332234 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 36064876 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 36064876 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 33800392 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35760812 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 36141561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34351414 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32140428 — Surrogate Endpoint (SUR): Blood pressure
Study 33755863 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study 33711380 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 33711380 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33711380 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32757523 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 34525247 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35697571 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 35816621 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 32987892 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32987892 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35989346 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 34125135 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 32242145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33881710 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35669738 — Surrogate Endpoint (SUR): Blood pressure
Study 33896388 — Surrogate Endpoint (SUR): Blood pressure
Study 34009291 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 33589320 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33589320 — Predictive Biomarker (PRD): PCSK7 mRNA
Genes: PCSK7; LPC; PC7; PC8; SPC7
Study 32761844 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32761844 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35481935 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32352320 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35373340 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32866624 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 32866624 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 32866624 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32992785 — Surrogate Endpoint (SUR): Probing pocket depth
Study 36197287 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32291360 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 33600092 — Predictive Biomarker (PRD): GK2 mRNA
Genes: GK2; GKP2; GKTA
Study 33548159 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 34031262 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 33026143 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33964325 — Surrogate Endpoint (SUR): Serum testosterone
Study 34561086 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32294560 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 36371994 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33245905 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35980383 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 32997825 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 32997825 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35347399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34070866 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 36012890 — Surrogate Endpoint (SUR): Blood pressure
Study 33420287 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 32006484 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 33819238 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33819238 — Surrogate Endpoint (SUR): Serum creatinine
Study 34029521 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34969649 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 35772219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35422427 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 35422427 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 32114729 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34089483 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33638801 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 34883305 — Surrogate Endpoint (SUR): Blood pressure
Study 32990454 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 33316426 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 33777424 — Surrogate Endpoint (SUR): Blood pressure
Study 34987499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32003737 — Surrogate Endpoint (SUR): Blood pressure
Study 32003737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32003737 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35580621 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 34879449 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 33023946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33023946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33023946 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 33023946 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 33418231 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 32805740 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32707001 — Predictive Biomarker (PRD): ITGA5 mRNA
Genes: ITGA5; FNRA
Study 32707001 — Predictive Biomarker (PRD): CD93 mRNA
Genes: CD93; C1QR1; MXRA4
Study 32707001 — Monitoring Biomarker (MOI): miR-92a-3p
Study 35263681 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 33441157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33142016 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35710395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33213400 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 34018342 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study 34090495 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34704877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33887429 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 33887429 — Surrogate Endpoint (SUR): Blood pressure
Study 33573681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33573681 — Monitoring Biomarker (MOI): Procalcitonin
Study 32661522 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32591594 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 32618244 — Predictive Biomarker (PRD): DDT mRNA
Genes: DDT
Study 33067295 — Surrogate Endpoint (SUR): Blood pressure
Study 33208263 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 33208263 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 35720377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35720377 — Safety Biomarker (SAF): Reactive oxygen species
Study 32645163 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32891918 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33028054 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 36167610 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 36167610 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 36167610 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 34634368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32053110 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 32053110 — Predictive Biomarker (PRD): GPR55 mRNA
Genes: GPR55
Study 32053110 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 33001140 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 35347429 — Surrogate Endpoint (SUR): Bone mineral density
Study 32646462 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 35395080 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 35395080 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 33979451 — Predictive Biomarker (PRD): Cyclin-dependent kinase-like 5
Genes: CDKL5; STK9
Study 34911462 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34911462 — Surrogate Endpoint (SUR): Serum sodium
Study 33768772 — Surrogate Endpoint (SUR): Blood pressure
Study 34941131 — Surrogate Endpoint (SUR): Blood pressure
Study 33951265 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34861374 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35228754 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32696816 — Predictive Biomarker (PRD): SACS mRNA
Genes: SACS; KIAA0730
Study 33225554 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 33225554 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 33225554 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34959836 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33415859 — Surrogate Endpoint (SUR): Blood pressure
Study 34762375 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33711081 — Predictive Biomarker (PRD): EEF1A2 mRNA
Genes: EEF1A2; EEF1AL; STN
Study 32899117 — Predictive Biomarker (PRD): BMAL1 mRNA
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study 33858221 — Predictive Biomarker (PRD): CGB8 mRNA
Genes: CGB3; CGB; CGB5; CGB8
Study 33372185 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35170727 — Surrogate Endpoint (SUR): Bone mineral density
Study 33658261 — Surrogate Endpoint (SUR): Blood pressure
Study 35361446 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34555421 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 32548283 — Surrogate Endpoint (SUR): Pathological complete response
Study 33941192 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35003321 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32037653 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 35486014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32682793 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 32399662 — Surrogate Endpoint (SUR): Blood pressure
Study 32580813 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32770262 — Predictive Biomarker (PRD): TRPV2 mRNA
Genes: TRPV2; VRL
Study 36323488 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 32909326 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32909326 — Surrogate Endpoint (SUR): Blood pressure
Study 33684370 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35655124 — Predictive Biomarker (PRD): SOD3 mRNA
Genes: SOD3
Study 35655124 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33761061 — Surrogate Endpoint (SUR): Blood pressure
Study 33864070 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33864070 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 34167567 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 33388426 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33388426 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 32389610 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 35581440 — Predictive Biomarker (PRD): AIF1 mRNA
Genes: AIF1; G1; IBA1
Study 32014035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32730174 — Surrogate Endpoint (SUR): Blood pressure
Study 34192430 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 32466070 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 33123968 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 32394350 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34692842 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36158129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36158129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34041932 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35100468 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35100468 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35100468 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 36204512 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36858705 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32779246 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 34505919 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 34505919 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 32013700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32013700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32613672 — Monitoring Biomarker (MOI): HBV DNA
Study 32979577 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 32652616 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 33929040 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35696698 — Surrogate Endpoint (SUR): Blood pressure
Study 33497135 — Surrogate Endpoint (SUR): Blood pressure
Study 33214158 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32417629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32417629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32417629 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 34298274 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 32543247 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 33258423 — Predictive Biomarker (PRD): TUB mRNA
Genes: TUB
Study 33258423 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 33827963 — Surrogate Endpoint (SUR): Blood pressure
Study 34747202 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 34747202 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 34747202 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 34747202 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study 35857179 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 34906924 — Surrogate Endpoint (SUR): Blood pressure
Study 34906924 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34371870 — Surrogate Endpoint (SUR): Bone mineral density
Study 35012809 — Surrogate Endpoint (SUR): Blood pressure
Study 34032718 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 36387986 — Surrogate Endpoint (SUR): Blood pressure