TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35669487 — Surrogate Endpoint (SUR): Bone mineral density
Study 32532328 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 34598935 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32859143 — Surrogate Endpoint (SUR): Blood pressure
Study 33617303 — Surrogate Endpoint (SUR): Serum testosterone
Study 33242637 — Surrogate Endpoint (SUR): Blood pressure
Study 34906235 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32324888 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 34168648 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 34168648 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ADAM11 mRNA
Genes: ADAM11; MDC
Study 34168648 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 33128535 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33128535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33128535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34265434 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34325885 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35463059 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35463059 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35049127 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 32392231 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32901094 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33180376 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 36333954 — Surrogate Endpoint (SUR): Bone mineral density
Study 32725695 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 34198888 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35559993 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 35559993 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FLNA mRNA
Genes: FLNA; FLN; FLN1
Study 32350413 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 32350413 — Safety Biomarker (SAF): CDA
Genes: CDD
Study 35861827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35861827 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35861827 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35977548 — Surrogate Endpoint (SUR): Bone mineral density
Study 34227081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36478476 — Predictive Biomarker (PRD): PDE4B mRNA
Genes: PDE4B; DPDE4
Study 36478476 — Predictive Biomarker (PRD): PDE4D mRNA
Genes: PDE4D; DPDE3
Study 33908683 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32545396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32545396 — Surrogate Endpoint (SUR): Blood pressure
Study 34982493 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 34887234 — Predictive Biomarker (PRD): SOX2 mRNA
Genes: SOX2
Study 34887234 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 34887234 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33625666 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33123888 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 35283116 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 36262871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36262871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36262871 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36262871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33884840 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35261115 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 32100190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32100190 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 34627582 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 35567889 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 35791646 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32838353 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32805198 — Surrogate Endpoint (SUR): Blood pressure
Study 35466156 — Surrogate Endpoint (SUR): Serum creatinine
Study 36005883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36005883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33392769 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32070283 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 33874750 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33422288 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36033731 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 616768438 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 616768438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32445429 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 33581920 — Predictive Biomarker (PRD): SPR mRNA
Genes: SPR
Study 33109654 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 33258553 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 35578688 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 33860389 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35971135 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 35971135 — Surrogate Endpoint (SUR): Blood pressure
Study 33605002 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 34690012 — Surrogate Endpoint (SUR): Blood pressure
Study 35120640 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32744034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32929215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32601075 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36229710 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32244777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32244777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34740884 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 36452042 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36452042 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 36452042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36452042 — Safety Biomarker (SAF): BDNF
Study 34587358 — Safety Biomarker (SAF): Hyaluronic acid
Study 34587358 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32252100 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 35791588 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34587253 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 34587253 — Safety Biomarker (SAF): C-X-C motif chemokine 5
Genes: CXCL5; ENA78; SCYB5
Study 34587253 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL6 mRNA
Genes: CXCL6; GCP2; SCYB6
Study 34587253 — Predictive Biomarker (PRD): TNFSF14 mRNA
Genes: TNFSF14; HVEML; LIGHT; UNQ391/PRO726
Study 36437688 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 36437688 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33674187 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33674187 — Predictive Biomarker (PRD): MMP11 mRNA
Genes: MMP11; STMY3
Study 33891981 — Safety Biomarker (SAF): Th2 cell
Study 34841959 — Surrogate Endpoint (SUR): Blood pressure
Study 32989261 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34143979 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34143979 — Predictive Biomarker (PRD): Hormone receptor
Study 33188493 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33188493 — Surrogate Endpoint (SUR): Blood pressure
Study 35122766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35367874 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 33148481 — Surrogate Endpoint (SUR): Serum calcium
Study 36216355 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36216355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36216355 — Safety Biomarker (SAF): BDNF
Study 32244252 — Surrogate Endpoint (SUR): Hematologic response
Study 33662659 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 33847575 — Surrogate Endpoint (SUR): Blood pressure
Study 34196240 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34196240 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 36121246 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 36121246 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 33743111 — Predictive Biomarker (PRD): miR-187
Genes: MIR187
Study 33276345 — Predictive Biomarker (PRD): LIPA mRNA
Genes: LIPA
Study 32646501 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33837377 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 33837377 — Predictive Biomarker (PRD): IL10RB mRNA
Genes: IL10RB; CRFB4; D21S58; D21S66
Study 32459423 — Surrogate Endpoint (SUR): Bone mineral density
Study 35246396 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 34874182 — Predictive Biomarker (PRD): Hormone receptor
Study 32635503 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34243225 — Surrogate Endpoint (SUR): Blood pressure
Study 36189925 — Safety Biomarker (SAF): Hyaluronic acid
Study 35946019 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 35438802 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 35438802 — Predictive Biomarker (PRD): PTPN11 mRNA
Genes: PTPN11; PTP2C; SHPTP2
Study 35438802 — Predictive Biomarker (PRD): CSF3R mRNA
Genes: CSF3R; GCSFR
Study 35438802 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 32506861 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 35532913 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 32022459 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32022459 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 33451345 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33451345 — Predictive Biomarker (PRD): Hormone receptor
Study 34704480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32459070 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 35481712 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35481712 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 35481712 — Safety Biomarker (SAF): Platelet to lymphocyte
Study 32627420 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 32627420 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 34731574 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33160854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33160854 — Monitoring Biomarker (MOI): Procalcitonin
Study 35688662 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 35688662 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 32072071 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 32072071 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 35231769 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 35231769 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34194240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34194240 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 36397128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36397128 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 36397128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36397128 — Safety Biomarker (SAF): Reactive oxygen species
Study 36695874 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35044471 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 35010917 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 36045183 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 34917633 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33468518 — Surrogate Endpoint (SUR): Blood pressure
Study 33017580 — Surrogate Endpoint (SUR): Blood pressure
Study 35120864 — Surrogate Endpoint (SUR): Blood pressure
Study 35566643 — Safety Biomarker (SAF): Hyaluronic acid
Study 35511451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34099065 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 34261530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34518469 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34144282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33824584 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33137352 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 33137352 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 33137352 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 34678118 — Surrogate Endpoint (SUR): Bone mineral density
Study 32234715 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 33961145 — Surrogate Endpoint (SUR): Blood pressure
Study 33677450 — Surrogate Endpoint (SUR): Serum potassium
Study 33108379 — Surrogate Endpoint (SUR): Blood pressure
Study 36203797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36203797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36203797 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 33476537 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study 33476537 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 33476537 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 35778977 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 36266551 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 36440618 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36440618 — Surrogate Endpoint (SUR): Blood pressure
Study 32341247 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 32769818 — Surrogate Endpoint (SUR): Blood pressure
Study 34058717 — Surrogate Endpoint (SUR): Blood pressure
Study 36199107 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 35002241 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35002241 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 35002241 — Safety Biomarker (SAF): BDNF
Study 35002241 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32359843 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32359843 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34083663 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 34083663 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 33236949 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33236949 — Safety Biomarker (SAF): BDNF
Study 32159857 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 34691317 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 34691317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36498228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36498228 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36301752 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 34761595 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34761595 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34761595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34761595 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 34761595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34761595 — Safety Biomarker (SAF): IL-6 and IL-10
Study 33465818 — Predictive Biomarker (PRD): DDAH1 mRNA
Genes: DDAH1; DDAH
Study 32898318 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 32939553 — Predictive Biomarker (PRD): CCR9 mRNA
Genes: CCR9; GPR28
Study 32939553 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 32939553 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33049114 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 32444867 — Surrogate Endpoint (SUR): Complete renal response
Study 34229078 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32011717 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 32011717 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36368336 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35761317 — Surrogate Endpoint (SUR): Blood pressure
Study 36048797 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 36190113 — Predictive Biomarker (PRD): LIPA mRNA
Genes: LIPA
Study 36190113 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 36190113 — Surrogate Endpoint (SUR): Blood pressure
Study 36190113 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35565077 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32567217 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 33337391 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 33337391 — Surrogate Endpoint (SUR): Serum sodium
Study 34904270 — Predictive Biomarker (PRD): Hormone receptor
Study 34904270 — Surrogate Endpoint (SUR): Bone mineral density
Study 34126560 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 36244652 — Surrogate Endpoint (SUR): Serum potassium
Study 32300799 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32300799 — Safety Biomarker (SAF): BDNF
Study 32674229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32674229 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35094006 — Surrogate Endpoint (SUR): Bone mineral density
Study 35799658 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 33875429 — Predictive Biomarker (PRD): TBP mRNA
Genes: TBP; GTF2D1; TF2D; TFIID
Study 34676521 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33994585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36239414 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 34498484 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35978355 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 33518321 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33518321 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1