TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32425222 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 35232215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35232215 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35418080 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32479794 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32479794 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 34201795 — Predictive Biomarker (PRD): MC1R mRNA
Genes: MC1R; MSHR
Study 34454580 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 34454580 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35966092 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 32208960 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32208960 — Monitoring Biomarker (MOI): Cell-free DNA
Study 33498461 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 33789001 — Safety Biomarker (SAF): Glycerol backbone
Study 34951042 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 36372094 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 32376628 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32376628 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 33155295 — Surrogate Endpoint (SUR): Blood pressure
Study 32694412 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32988930 — Predictive Biomarker (PRD): MAVS mRNA
Genes: MAVS; IPS1; KIAA1271; VISA
Study 33142117 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 35469509 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 33128722 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35505117 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 35710164 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 35710164 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35710164 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32932244 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 35131614 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33736819 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33712030 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 36441433 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 32005283 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 35094695 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33915363 — Surrogate Endpoint (SUR): Blood pressure
Study 33721439 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 35859328 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35859328 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 616667359 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32053254 — Surrogate Endpoint (SUR): Blood pressure
Study 33946085 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32321350 — Safety Biomarker (SAF): Reactive oxygen species
Study 35509490 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35509490 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 33647946 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 33647946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33647946 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35278336 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 35278336 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35278336 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35077296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36176927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34170932 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33246428 — Surrogate Endpoint (SUR): Pathological complete response
Study 35728369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35728369 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 36302567 — Surrogate Endpoint (SUR): Complete renal response
Study 33809392 — Surrogate Endpoint (SUR): Blood pressure
Study 33809392 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32933470 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35905418 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 32178701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32178701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32178701 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32178701 — Safety Biomarker (SAF): Interleukin 1
Study 32178701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32178701 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 32178701 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 34830950 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 35432383 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33527809 — Surrogate Endpoint (SUR): Blood pressure
Study 32232767 — Safety Biomarker (SAF): miR-146b
Genes: MIR146B
Study 34203476 — Surrogate Endpoint (SUR): Blood pressure
Study 32381843 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32830463 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 32830463 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 34913186 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 34913186 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 32294652 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 32294652 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 32294652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32294652 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34182967 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 36160152 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33111932 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 36035633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35684022 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35684022 — Surrogate Endpoint (SUR): Blood pressure
Study 32350172 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32350172 — Surrogate Endpoint (SUR): Serum creatinine
Study 34635569 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 35167505 — Surrogate Endpoint (SUR): Blood pressure
Study 33180001 — Surrogate Endpoint (SUR): Blood pressure
Study 34776874 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 34984851 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34632798 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 34632798 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 35674747 — Surrogate Endpoint (SUR): Blood pressure
Study 33504211 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 34339851 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33577373 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34645147 — Monitoring Biomarker (MOI): Procalcitonin
Study 34645147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34645147 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35731737 — Predictive Biomarker (PRD): APEX1 mRNA
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 33789616 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34549356 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 34549356 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 35812820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32546431 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 36412685 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34366306 — Surrogate Endpoint (SUR): Blood pressure
Study 33119010 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 33119010 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34460132 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34460132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35536547 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 33215434 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 33483965 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 32432556 — Surrogate Endpoint (SUR): Blood pressure
Study 34561890 — Predictive Biomarker (PRD): ABCD2 mRNA
Genes: ABCD2; ALD1; ALDL1; ALDR; ALDRP
Study 32556865 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 32556865 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 32556865 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 32556865 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35642490 — Surrogate Endpoint (SUR): Blood pressure
Study 33436709 — Surrogate Endpoint (SUR): Blood pressure
Study 35915198 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 33331923 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34049857 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 34696998 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 34368848 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35060417 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 35643392 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32020725 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 34514678 — Monitoring Biomarker (MOI): HBV DNA
Study 35560363 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 35045098 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 34435273 — Safety Biomarker (SAF): miR-142
Genes: MIR142
Study 34435273 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-125b
Study 32964458 — Surrogate Endpoint (SUR): Blood pressure
Study 35314635 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35314635 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32594779 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34607519 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34607519 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32463456 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32463456 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 33761288 — Surrogate Endpoint (SUR): Blood pressure
Study 33093616 — Surrogate Endpoint (SUR): Blood pressure
Study 33093616 — Surrogate Endpoint (SUR): Serum creatinine
Study 32829060 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 32829060 — Predictive Biomarker (PRD): UCN3 mRNA
Genes: UCN3; SPC
Study 35258271 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36051936 — Predictive Biomarker (PRD): ITK mRNA
Genes: ITK; EMT; LYK
Study 32768001 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 35987076 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 35987076 — Predictive Biomarker (PRD): HOXA10 mRNA
Genes: HOXA10; HOX1H
Study 34261483 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33857750 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34202690 — Surrogate Endpoint (SUR): Blood pressure
Study 34202690 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32967704 — Surrogate Endpoint (SUR): Blood pressure
Study 34083615 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 32897437 — Surrogate Endpoint (SUR): Serum creatinine
Study 34779837 — Surrogate Endpoint (SUR): Serum sodium
Study 36026840 — Surrogate Endpoint (SUR): Blood pressure
Study 33514760 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 35636174 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 33688020 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 616062859 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 616062859 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 32019488 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32019488 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32019488 — Surrogate Endpoint (SUR): Serum creatinine
Study 34021767 — Predictive Biomarker (PRD): BCAR1 mRNA
Genes: BCAR1; CAS; CASS1; CRKAS
Study 32615777 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 32615777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33499847 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 33499847 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 33499847 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 33499847 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 32567238 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35768736 — Surrogate Endpoint (SUR): Blood pressure
Study 34405393 — Predictive Biomarker (PRD): RARA mRNA
Genes: RARA; NR1B1
Study 32067615 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 32067615 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32559734 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32559734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32559734 — Surrogate Endpoint (SUR): Blood pressure
Study 32559734 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32989456 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34169551 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34169551 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34169551 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33986070 — Surrogate Endpoint (SUR): Blood pressure
Study 35261049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35261049 — Surrogate Endpoint (SUR): Blood pressure
Study 35261049 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 35431172 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34544808 — Surrogate Endpoint (SUR): Bone mineral density
Study 32286934 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 34176448 — Predictive Biomarker (PRD): COMMD3 mRNA
Genes: COMMD3; BUP; C10orf8
Study 34854982 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 34854982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34798808 — Predictive Biomarker (PRD): DKK3 mRNA
Genes: DKK3; REIC; UNQ258/PRO295
Study 34798808 — Predictive Biomarker (PRD): ESM1 mRNA
Genes: ESM1
Study 34798808 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 34798808 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 34798808 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 34798808 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 34798808 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35768875 — Surrogate Endpoint (SUR): Blood pressure
Study 33143655 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 35412366 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 34563211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34563211 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34563211 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 34563211 — Safety Biomarker (SAF): Interleukin 1
Study 34563211 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34617520 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34617520 — Safety Biomarker (SAF): Reactive oxygen species
Study 33577574 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 33577574 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32398047 — Surrogate Endpoint (SUR): Blood pressure
Study 33175348 — Surrogate Endpoint (SUR): Blood pressure
Study 33175348 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33175348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34016347 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34016347 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 35427803 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36321459 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34053745 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 34053745 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34053745 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34526064 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34526064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32440750 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 33167920 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 32826324 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 35079115 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 35079115 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36455988 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 36047065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36047065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36047065 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 36047065 — Safety Biomarker (SAF): Interleukin 1
Study 32598751 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32294698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32294698 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 34236413 — Surrogate Endpoint (SUR): Blood pressure
Study 34766913 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34766913 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32328834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33621788 — Predictive Biomarker (PRD): CALR mRNA
Genes: CALR; CRTC
Study 33621788 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 32531432 — Predictive Biomarker (PRD): EEA1 mRNA
Genes: EEA1; ZFYVE2
Study 32531432 — Predictive Biomarker (PRD): TRIM59 mRNA
Genes: TRIM59; RNF104; TRIM57; TSBF1
Study 32531432 — Predictive Biomarker (PRD): ABCA7 mRNA
Genes: ABCA7
Study 32531432 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 32531432 — Safety Biomarker (SAF): HLA-DQA1
Genes: CELIAC1
Study 32531432 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 33707520 — Surrogate Endpoint (SUR): Blood pressure
Study 34535967 — Surrogate Endpoint (SUR): Bone mineral density
Study 34533295 — Surrogate Endpoint (SUR): Blood pressure
Study 35451681 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32604148 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34109590 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34109590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34109590 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 33131315 — Surrogate Endpoint (SUR): Blood pressure