TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32640027 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32640027 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33837400 — Surrogate Endpoint (SUR): Blood pressure
Study 32252684 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32252684 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34388396 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 35781772 — Surrogate Endpoint (SUR): Urinary oxalate
Study 35681088 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 35681088 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33319651 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 33319651 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 33319651 — Predictive Biomarker (PRD): UCHL1 mRNA
Genes: UCHL1
Study 34637336 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 34637336 — Predictive Biomarker (PRD): Microsatellite instability
Study 35457579 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32476258 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35742385 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 32943290 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34499045 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 33722257 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 33722257 — Surrogate Endpoint (SUR): Serum sodium
Study 32004317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32821939 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36383914 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35761117 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 34058100 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34058100 — Surrogate Endpoint (SUR): Blood pressure
Study 32728162 — Predictive Biomarker (PRD): WDHD1 mRNA
Genes: WDHD1; AND1
Study 32728162 — Predictive Biomarker (PRD): DNM1L mRNA
Genes: DNM1L; DLP1; DRP1
Study 32728162 — Predictive Biomarker (PRD): PKP2 mRNA
Genes: PKP2
Study 32728162 — Predictive Biomarker (PRD): TNKS mRNA
Genes: TNKS; PARP5A; PARPL; TIN1; TINF1; TNKS1
Study 32728162 — Predictive Biomarker (PRD): CYP4B1 mRNA
Genes: CYP4B1
Study 32728162 — Predictive Biomarker (PRD): CYP4X1 mRNA
Genes: CYP4X1; UNQ1929/PRO4404
Study 32728162 — Predictive Biomarker (PRD): EPHX1 mRNA
Genes: EPHX1; EPHX; EPOX
Study 32728162 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 32728162 — Predictive Biomarker (PRD): SIGLEC5 mRNA
Genes: SIGLEC5; CD33L2; OBBP2
Study 32728162 — Predictive Biomarker (PRD): SIGLEC7 mRNA
Genes: SIGLEC7; AIRM1
Study 35833528 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33272623 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 34330170 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 34622762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32959898 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32960847 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34474282 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 32692000 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32692000 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32979576 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33023276 — Surrogate Endpoint (SUR): Blood pressure
Study 35562742 — Surrogate Endpoint (SUR): Blood pressure
Study 34418549 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 35152272 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 35152272 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 35542976 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35542976 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35542976 — Surrogate Endpoint (SUR): Blood pressure
Study 36328879 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 36328879 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 32462261 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34212533 — Surrogate Endpoint (SUR): Serum creatinine
Study 33631065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34445043 — Surrogate Endpoint (SUR): Blood pressure
Study 34445043 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36306807 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 32115035 — Predictive Biomarker (PRD): SLC38A2 mRNA
Genes: SLC38A2; ATA2; KIAA1382; SAT2; SNAT2
Study 32115035 — Predictive Biomarker (PRD): SLC1A4 mRNA
Genes: SLC1A4; ASCT1; SATT
Study 32115035 — Predictive Biomarker (PRD): SLC7A5 mRNA
Genes: SLC7A5; CD98LC; LAT1; MPE16
Study 32115035 — Predictive Biomarker (PRD): CRAT mRNA
Genes: CRAT; CAT1
Study 32115035 — Predictive Biomarker (PRD): SLC6A19 mRNA
Genes: SLC6A19; B0AT1
Study 32115035 — Safety Biomarker (SAF): Glutamate dehydrogenase
Study 32195960 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 32135010 — Surrogate Endpoint (SUR): Blood pressure
Study 34157116 — Surrogate Endpoint (SUR): Bone mineral density
Study 34589887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34589887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34589887 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 35206179 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32327254 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32327254 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34000236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35463130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35463130 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32635494 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32635494 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35690859 — Monitoring Biomarker (MOI): Cell-free DNA
Study 33959169 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33607244 — Surrogate Endpoint (SUR): Blood pressure
Study 32825817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32825817 — Monitoring Biomarker (MOI): Procalcitonin
Study 32825817 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32825817 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32825817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34608092 — Safety Biomarker (SAF): Hyaluronic acid
Study 33030563 — Surrogate Endpoint (SUR): Bone mineral density
Study 32947017 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33536005 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 36367386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33434277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35113430 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34320390 — Predictive Biomarker (PRD): PRF1
Genes: PFP; P1; HPLH2
Study 32428202 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 35551149 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 35551149 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 35551149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35551149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35551149 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33336508 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study 33336508 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 33336508 — Predictive Biomarker (PRD): OAS1 mRNA
Genes: OAS1; OIAS
Study 33222989 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36128500 — Safety Biomarker (SAF): Hyaluronic acid
Study 35960871 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 32833539 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 35867146 — Surrogate Endpoint (SUR): Blood pressure
Study 34139706 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 36223962 — Predictive Biomarker (PRD): FUT1 mRNA
Genes: FUT1; H; HSC
Study 32810387 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 36101802 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 33866329 — Predictive Biomarker (PRD): BTN3A2 mRNA
Genes: BTN3A2; BT3.2; BTF3; BTF4
Study 32864685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32453997 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32453997 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 32453997 — Safety Biomarker (SAF): BDNF
Study 32497454 — Surrogate Endpoint (SUR): Blood pressure
Study 32243385 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 33907133 — Surrogate Endpoint (SUR): Blood pressure
Study 33808476 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33808476 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 35368058 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34496115 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32501612 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32501612 — Surrogate Endpoint (SUR): Blood pressure
Study 35368961 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35368961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35368961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35368961 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 35368961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35368961 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32926841 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 32223381 — Surrogate Endpoint (SUR): Blood pressure
Study 34023321 — Predictive Biomarker (PRD): Hormone receptor
Study 35932165 — Surrogate Endpoint (SUR): Blood pressure
Study 35932165 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33443368 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 33443368 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 33726840 — Surrogate Endpoint (SUR): Blood pressure
Study 35685671 — Monitoring Biomarker (MOI): Procalcitonin
Study 35685671 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35685671 — Surrogate Endpoint (SUR): Serum calcium
Study 32975391 — Surrogate Endpoint (SUR): Blood pressure
Study 35608826 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32696695 — Surrogate Endpoint (SUR): Blood pressure
Study 35224710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34333803 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34333803 — Surrogate Endpoint (SUR): Blood pressure
Study 34333803 — Surrogate Endpoint (SUR): Serum triglycerides
Study 34333803 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33713359 — Predictive Biomarker (PRD): Hormone receptor
Study 33185897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33185897 — Surrogate Endpoint (SUR): Bone mineral density
Study 35766559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35766559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35766559 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 35089964 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32012190 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 32012190 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32340248 — Surrogate Endpoint (SUR): Blood pressure
Study 32340248 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32340248 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34699278 — Predictive Biomarker (PRD): MSN mRNA
Genes: MSN
Study 35712521 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36074816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34606560 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 36353999 — Surrogate Endpoint (SUR): Blood pressure
Study 33987915 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 32838673 — Surrogate Endpoint (SUR): Blood pressure
Study 32838673 — Surrogate Endpoint (SUR): Serum creatinine
Study 33375174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33375174 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 32710677 — Surrogate Endpoint (SUR): Blood pressure
Study 35068386 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 33512419 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 34999282 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 34999282 — Surrogate Endpoint (SUR): Serum creatinine
Study 35241720 — Surrogate Endpoint (SUR): Blood pressure
Study 33140878 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 32370596 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35508008 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33315809 — Surrogate Endpoint (SUR): Blood pressure
Study 33407599 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32885637 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 35690931 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 35690931 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 34609451 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 36465647 — Predictive Biomarker (PRD): RUNX2 mRNA
Genes: RUNX2; AML3; CBFA1; OSF2; PEBP2A
Study 36465647 — Predictive Biomarker (PRD): BMP2 mRNA
Genes: BMP2; BMP2A
Study 36465647 — Surrogate Endpoint (SUR): Bone mineral density
Study 35247794 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 32594511 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 33411992 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 36326117 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 36326117 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35468091 — Surrogate Endpoint (SUR): Blood pressure
Study 35776183 — Predictive Biomarker (PRD): PPP1R14C mRNA
Genes: PPP1R14C; KEPI
Study 35776183 — Predictive Biomarker (PRD): SUPT20H mRNA
Genes: SUPT20H; C13orf19; FAM48A; FP757
Study 35776183 — Predictive Biomarker (PRD): Hormone receptor
Study 33939911 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34654493 — Surrogate Endpoint (SUR): Blood pressure
Study 34980285 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 32613634 — Surrogate Endpoint (SUR): Blood pressure
Study 33857594 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 35577631 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 35577631 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33298104 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 36341700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32956615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32703634 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 32703634 — Surrogate Endpoint (SUR): Serum triglycerides
Study 34463869 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 33200512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32178766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35793185 — Surrogate Endpoint (SUR): Blood pressure
Study 32989491 — Surrogate Endpoint (SUR): Bone mineral density
Study 33106171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33106171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35271380 — Surrogate Endpoint (SUR): Bone mineral density
Study 33180360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35075017 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35441435 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35441435 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 36164101 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study 36164101 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 36164101 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 34770227 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 35833334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35662232 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35662232 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35662232 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35745238 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33541457 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 32602032 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 32362166 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 33656249 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33269486 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35904639 — Surrogate Endpoint (SUR): Serum calcium
Study 35572982 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 32209449 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 32965617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32851921 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 35237700 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35237700 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 33788599 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 35973009 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 35398549 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 34391294 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36056908 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 32451909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32451909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32838647 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 32838647 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 34929030 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34147014 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35863457 — Predictive Biomarker (PRD): CYP51A1 mRNA
Genes: CYP51A1; CYP51
Study 32812667 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 35238476 — Surrogate Endpoint (SUR): Plasma ammonia
Study 32918131 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32561673 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 32561673 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study 35667400 — Surrogate Endpoint (SUR): Blood pressure
Study 34853086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32867690 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32867690 — Surrogate Endpoint (SUR): Serum creatinine