TrialPanorama/TrialPanorama-database huggingface dataset:
Study 37864281 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 37864379 — Surrogate Endpoint (SUR): Blood pressure
Study 37864379 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 37864379 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37864646 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 37864885 — Predictive Biomarker (PRD): PAK4 mRNA
Genes: PAK4; KIAA1142
Study 37865043 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37865048 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37865291 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 37865291 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 37865397 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 37865397 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 37865397 — Surrogate Endpoint (SUR): Pathological complete response
Study 37865752 — Surrogate Endpoint (SUR): Bone mineral density
Study 37865896 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37866460 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 37867420 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 37868660 — Surrogate Endpoint (SUR): Blood pressure
Study 37868959 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 37868959 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 37868959 — Safety Biomarker (SAF): Interleukin 1
Study 37869030 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 37869360 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 37869406 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 37870510 — Predictive Biomarker (PRD): TACR3 mRNA
Genes: TACR3; NK3R; TAC3R
Study 37870536 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37870836 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 37870920 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 37870954 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 37870954 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 37870955 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 37870955 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 37870968 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 37870968 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37870969 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 37870974 — Surrogate Endpoint (SUR): Pathological complete response
Study 37870973 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 37870976 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37871300 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 37871300 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 37871306 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 37871306 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37871309 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 37871555 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37871576 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 37871604 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37871959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37871959 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 37871997 — Surrogate Endpoint (SUR): Blood pressure
Study 37872225 — Predictive Biomarker (PRD): CLDN6 mRNA
Genes: CLDN6; UNQ757/PRO1488
Study 37872497 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 37872582 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37872654 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37873555 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 37873863 — Predictive Biomarker (PRD): SLC1A5 mRNA
Genes: SLC1A5; ASCT2; M7V1; RDR; RDRC
Study 37874103 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 37874111 — Predictive Biomarker (PRD): TOMM40 mRNA
Genes: TOMM40; C19orf1; PEREC1; TOM40
Study 37874111 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 37874403 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 37874403 — Surrogate Endpoint (SUR): Serum uric acid
Study 37874655 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 37875143 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37875178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37875178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37875178 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 37875178 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 37875178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37875323 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37875429 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37875494 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 37875559 — Surrogate Endpoint (SUR): Blood pressure
Study 37875771 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 37875997 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 37875997 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 37876229 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 37876229 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 37876886 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 37878148 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37878148 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37878148 — Predictive Biomarker (PRD): Hormone receptor
Study 37878497 — Predictive Biomarker (PRD): WARS1 mRNA
Genes: WARS1; IFI53; WARS; WRS
Study 37878497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37878624 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 37878624 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 37878624 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 37879047 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 37879393 — Predictive Biomarker (PRD): FTCD mRNA
Genes: FTCD
Study 37879536 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 37879536 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37879695 — Predictive Biomarker (PRD): SSTR2 mRNA
Genes: SSTR2
Study 37879886 — Monitoring Biomarker (MOI): HBV DNA
Study 37880076 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 37880303 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 37880499 — Surrogate Endpoint (SUR): Blood pressure
Study 37880581 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 37880682 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 37880704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37880931 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37881307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37881306 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 37882432 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 37882668 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 37882668 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 37882668 — Predictive Biomarker (PRD): Induced myeloid leukemia cell differentiation protein Mcl-1
Genes: MCL1; BCL2L3
Study 37882668 — Predictive Biomarker (PRD): TP53RK mRNA
Genes: TP53RK; C20orf64; PRPK
Study 37882706 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37882974 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37883003 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 37883003 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37883059 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37883073 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 37883723 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37883723 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37883723 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 37883727 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 37883795 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 37883795 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 37883795 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 37883784 — Surrogate Endpoint (SUR): Blood pressure
Study 37883803 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 37884063 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 37884680 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 37885041 — Predictive Biomarker (PRD): WNT10A mRNA
Genes: WNT10A
Study 37885041 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 37885482 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 37885795 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37885796 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37886601 — Predictive Biomarker (PRD): CAPN3 mRNA
Genes: CAPN3; CANP3; CANPL3; NCL1
Study 37886601 — Predictive Biomarker (PRD): ANO5 mRNA
Genes: ANO5; GDD1; TMEM16E
Study 37886601 — Predictive Biomarker (PRD): DYSF mRNA
Genes: DYSF; FER1L1
Study 37886601 — Predictive Biomarker (PRD): DNAJB6 mRNA
Genes: DNAJB6; HSJ2; MRJ; MSJ1
Study 37886601 — Predictive Biomarker (PRD): SGCA mRNA
Genes: SGCA; ADL; DAG2
Study 37886601 — Predictive Biomarker (PRD): SGCB mRNA
Genes: SGCB
Study 37886601 — Predictive Biomarker (PRD): SGCD mRNA
Genes: SGCD
Study 37886601 — Predictive Biomarker (PRD): SGCG mRNA
Genes: SGCG
Study 37886601 — Predictive Biomarker (PRD): FKRP mRNA
Genes: FKRP
Study 37886645 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 37886880 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37887530 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 37887871 — Predictive Biomarker (PRD): TCP1 mRNA
Genes: TCP1; CCT1; CCTA
Study 37889107 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 37889298 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37889298 — Predictive Biomarker (PRD): VPS39 mRNA
Genes: VPS39; KIAA0770; TLP; VAM6
Study 37889298 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 37889308 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 37889308 — Surrogate Endpoint (SUR): Forced vital capacity
Study 37889382 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 37889382 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 37889382 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 37889382 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 37889487 — Surrogate Endpoint (SUR): Blood pressure
Study 37890035 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37890143 — Surrogate Endpoint (SUR): Blood pressure
Study 37890351 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37890351 — Predictive Biomarker (PRD): Hormone receptor
Study 37890671 — Predictive Biomarker (PRD): SLC40A1 mRNA
Genes: SLC40A1; FPN; FPN1; IREG1; SLC11A3; MSTP079
Study 37890839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37890839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37891072 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 37891072 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37891146 — Surrogate Endpoint (SUR): Bone mineral density
Study 37891226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37891549 — Safety Biomarker (SAF): Hyaluronic acid
Study 37891608 — Predictive Biomarker (PRD): MZB1 mRNA
Genes: MZB1; MEDA7; PACAP; HSPC190
Study 37891608 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 37891608 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 37892656 — Surrogate Endpoint (SUR): Blood pressure
Study 37893050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37893050 — Monitoring Biomarker (MOI): Procalcitonin
Study 37894732 — Predictive Biomarker (PRD): ULK1 mRNA
Genes: ULK1; KIAA0722
Study 37895218 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 37896812 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 37897452 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 37897866 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study 37897866 — Predictive Biomarker (PRD): Microsatellite instability
Study 37898184 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 37898410 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 37898410 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37898410 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37898434 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37898434 — Surrogate Endpoint (SUR): Blood pressure
Study 37898434 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 37899145 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 37899297 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 37899477 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 37899477 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 37900149 — Surrogate Endpoint (SUR): Serum uric acid
Study 37901478 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 37902726 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37902733 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 37902819 — Surrogate Endpoint (SUR): Blood pressure
Study 37902861 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37902861 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 37903324 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 37903325 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 37903465 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 37903483 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 37903504 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 37903590 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37903607 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 37903607 — Surrogate Endpoint (SUR): Blood pressure
Study 37903679 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37903861 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 37903899 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37903899 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37903899 — Predictive Biomarker (PRD): Hormone receptor
Study 37905704 — Safety Biomarker (SAF): Hyaluronic acid
Study 37905734 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 37905734 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 37906406 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37906649 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37906649 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37906649 — Predictive Biomarker (PRD): Hormone receptor
Study 37907210 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37907305 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 37908359 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37909020 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37909020 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 37914483 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study 37914594 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37914804 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 37914804 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 37914804 — Safety Biomarker (SAF): Interleukin 1
Study 37914976 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37915546 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37915938 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 37916028 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 37916028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37916028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37916266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37916266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37916517 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 37916517 — Surrogate Endpoint (SUR): Blood pressure
Study 37916620 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 37916745 — Surrogate Endpoint (SUR): Serum creatinine
Study 37916926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37916926 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 37917058 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study 37917058 — Predictive Biomarker (PRD): Microsatellite instability
Study 37917063 — Surrogate Endpoint (SUR): Blood pressure
Study 37917187 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 37917187 — Pharmacodynamic Biomarker (PDY): 2-hydroxyglutarate
Study 37918066 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 37918404 — Predictive Biomarker (PRD): SLC25A21 mRNA
Genes: SLC25A21; ODC
Study 37918675 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37918933 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 37919456 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 37919742 — Surrogate Endpoint (SUR): Blood pressure
Study 37919791 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37919816 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 37920921 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 37921755 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37921755 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 37921755 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 37921769 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 37921846 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study 37922035 — Predictive Biomarker (PRD): SRCIN1 mRNA
Genes: SRCIN1; KIAA1684; P140; SNIP
Study 37922035 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 37922035 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study 37922035 — Safety Biomarker (SAF): Reactive oxygen species
Study 37922035 — Safety Biomarker (SAF): Interleukin 1
Study 37922438 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37922692 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 37922692 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 37922692 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37922692 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden