TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32719355 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 616952074 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 36255178 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 35787522 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33081828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33081828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35364216 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 35364216 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 35322793 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32740512 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32740512 — Surrogate Endpoint (SUR): Blood pressure
Study 32223649 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32223649 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34456270 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 34569167 — Surrogate Endpoint (SUR): Bone mineral density
Study 32904701 — Safety Biomarker (SAF): Reactive oxygen species
Study 32118753 — Predictive Biomarker (PRD): BTD mRNA
Genes: BTD
Study 33960181 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32807209 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 32036406 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36026988 — Surrogate Endpoint (SUR): Blood pressure
Study 36073362 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33290437 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 32943389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34062866 — Predictive Biomarker (PRD): PRKCE mRNA
Genes: PRKCE; PKCE
Study 33798312 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 34312798 — Monitoring Biomarker (MOI): HBV DNA
Study 32855275 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 32855275 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32149451 — Surrogate Endpoint (SUR): Serum potassium
Study 34750392 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34750392 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 34750392 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 34750392 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 34750392 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 33188428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33188428 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 33935686 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 33935686 — Surrogate Endpoint (SUR): Blood pressure
Study 32651307 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 32651307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32651307 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33032612 — Monitoring Biomarker (MOI): Procalcitonin
Study 33624417 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 33624417 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 32084347 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32084347 — Safety Biomarker (SAF): BDNF
Study 32473534 — Surrogate Endpoint (SUR): Blood pressure
Study 34519832 — Surrogate Endpoint (SUR): Bone mineral density
Study 33745203 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33745203 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33745203 — Surrogate Endpoint (SUR): Blood pressure
Study 33162978 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33162978 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 33009445 — Surrogate Endpoint (SUR): Blood pressure
Study 33515998 — Surrogate Endpoint (SUR): Bone mineral density
Study 33326257 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 33326257 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 35920686 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32195937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32195937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32195937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32195937 — Surrogate Endpoint (SUR): Blood pressure
Study 36335059 — Surrogate Endpoint (SUR): Blood pressure
Study 33921829 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34080789 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35346971 — Surrogate Endpoint (SUR): Blood pressure
Study 36001712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33124472 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33124472 — Surrogate Endpoint (SUR): Blood pressure
Study 33161844 — Predictive Biomarker (PRD): NOTCH3 mRNA
Genes: NOTCH3
Study 32925992 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 32553536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32553536 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32013614 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32487264 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 33028663 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32811627 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33923663 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 33212780 — Predictive Biomarker (PRD): SRSF6 mRNA
Genes: SRSF6; SFRS6; SRP55
Study 32385851 — Surrogate Endpoint (SUR): Blood pressure
Study 36371904 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 34472117 — Surrogate Endpoint (SUR): Blood pressure
Study 32861668 — Surrogate Endpoint (SUR): Blood pressure
Study 34244250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34244250 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34244250 — Safety Biomarker (SAF): Hyaluronic acid
Study 34244250 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 34244250 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 34244250 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32774912 — Surrogate Endpoint (SUR): Blood pressure
Study 33677724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36047138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36047138 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 36047138 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 32423694 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36227234 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 36227234 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32065775 — Surrogate Endpoint (SUR): Blood pressure
Study 32065775 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34763937 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 34763937 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 34763937 — Predictive Biomarker (PRD): LGSN mRNA
Genes: LGSN; GLULD1; LGS
Study 33955348 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 33595634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34515108 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 32041661 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 35165478 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32965691 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 32485785 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 32032416 — Surrogate Endpoint (SUR): Probing pocket depth
Study 35510597 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 33543283 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 33543283 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 32299482 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 32299482 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 32299482 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 32299482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32299482 — Predictive Biomarker (PRD); Safety Biomarker (SAF): WNT5A mRNA
Genes: WNT5A
Study 34389633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33357510 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 36361252 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 36361252 — Surrogate Endpoint (SUR): Blood pressure
Study 32581041 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36072375 — Surrogate Endpoint (SUR): Bone mineral density
Study 32450979 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 34872568 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 34872568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32732305 — Surrogate Endpoint (SUR): Blood pressure
Study 32233633 — Predictive Biomarker (PRD): CDKN3 mRNA
Genes: CDKN3; CDI1; CIP2; KAP
Study 35928886 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35928886 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32705692 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 36269852 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34315237 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34315237 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32628676 — Predictive Biomarker (PRD): SIRPA mRNA
Genes: SIRPA; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP
Study 32628676 — Predictive Biomarker (PRD): FGF5 mRNA
Genes: FGF5
Study 32628676 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Interleukin 6 receptor alpha
Genes: IL6R
Study 32628676 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 32628676 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 35157370 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 35157370 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 32164442 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34153968 — Surrogate Endpoint (SUR): Blood pressure
Study 34979252 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 34979252 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33096027 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 35975762 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33560138 — Predictive Biomarker (PRD): SEPHS1 mRNA
Genes: SEPHS1; SELD; SPS; SPS1
Study 33685404 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 32690499 — Predictive Biomarker (PRD): DAXX mRNA
Genes: DAXX; BING2; DAP6
Study 32690499 — Predictive Biomarker (PRD): ATRX mRNA
Genes: ATRX; RAD54L; XH2
Study 32690499 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 32690499 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 33517762 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33517762 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35745210 — Surrogate Endpoint (SUR): Blood pressure
Study 34024686 — Surrogate Endpoint (SUR): Blood pressure
Study 34024686 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32828503 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 36454571 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34244212 — Predictive Biomarker (PRD): SCARB1 mRNA
Genes: SCARB1; CD36L1; CLA1
Study 34244212 — Safety Biomarker (SAF): Reactive oxygen species
Study 33896812 — Safety Biomarker (SAF): Hyaluronic acid
Study 33764636 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 33764636 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34463270 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 36039391 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 32524862 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 32524862 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 32697872 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 33719084 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 32571327 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 32571327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32571327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32571327 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32571327 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34610830 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 33439693 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33439693 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 34599724 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34599724 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 34599724 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33022010 — Predictive Biomarker (PRD): PTBP2 mRNA
Genes: PTBP2; NPTB; PTB; PTBLP
Study 35397772 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 35894914 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 35898865 — Predictive Biomarker (PRD): UBXN11 mRNA
Genes: UBXN11; SOC; UBXD5; PP2243
Study 32265361 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33423518 — Surrogate Endpoint (SUR): Blood pressure
Study 36145139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33892316 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33017328 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33512754 — Surrogate Endpoint (SUR): Blood pressure
Study 33270123 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 33270123 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34184401 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34261332 — Surrogate Endpoint (SUR): Blood pressure
Study 33377451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32645159 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 32549135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35235993 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35644936 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35644936 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 34911336 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34911336 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 34363104 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 32868152 — Surrogate Endpoint (SUR): Blood pressure
Study 33350170 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 33350170 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 33350170 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study 33350170 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34476774 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 34476774 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 34224476 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 34224476 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 33305818 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 33305818 — Predictive Biomarker (PRD): GSTA3 mRNA
Genes: GSTA3
Study 33305818 — Predictive Biomarker (PRD): IL21R mRNA
Genes: IL21R; NILR; UNQ3121/PRO10273
Study 33305818 — Predictive Biomarker (PRD): KLF4 mRNA
Genes: KLF4; EZF; GKLF
Study 33305818 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33305818 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 33305818 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 35953083 — Predictive Biomarker (PRD): HYLS1 mRNA
Genes: HYLS1; HLS
Study 34400963 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 32456617 — Predictive Biomarker (PRD): NUBP1 mRNA
Genes: NUBP1; NBP; NBP1
Study 35924814 — Surrogate Endpoint (SUR): Blood pressure
Study 36137900 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33508723 — Surrogate Endpoint (SUR): Bone mineral density
Study 33067067 — Surrogate Endpoint (SUR): Blood pressure
Study 34617960 — Surrogate Endpoint (SUR): Blood pressure
Study 33387427 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33387427 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 32576351 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33361164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34399434 — Predictive Biomarker (PRD): PTBP2 mRNA
Genes: PTBP2; NPTB; PTB; PTBLP
Study 32948554 — Surrogate Endpoint (SUR): Blood pressure
Study 33545163 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 35512064 — Surrogate Endpoint (SUR): Blood pressure
Study 34139859 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33401219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32907617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32907617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32907617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33410885 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32305573 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 32305573 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 32951725 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34271953 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 34271953 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 34271953 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34271953 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 32020565 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 36027570 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32579776 — Monitoring Biomarker (MOI): HBV DNA
Study 36384100 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 36384100 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 35487730 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35487730 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35487730 — Monitoring Biomarker (MOI): Cell-free DNA
Study 35999026 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 35999026 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 35064574 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 35064574 — Surrogate Endpoint (SUR): Blood pressure
Study 34363050 — Surrogate Endpoint (SUR): Blood pressure
Study 34240659 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34913281 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34913281 — Surrogate Endpoint (SUR): Blood pressure
Study 34602400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34602400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33202559 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 33593885 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 33593885 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP