TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33497075 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33497075 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35594613 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33006394 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 35607441 — Surrogate Endpoint (SUR): Blood pressure
Study 33958973 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 33958973 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 33958973 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 32772383 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 32772383 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 32772383 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 35587847 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34282125 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34282125 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 34282125 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 34282125 — Predictive Biomarker (PRD): SDK1 mRNA
Genes: SDK1
Study 34282125 — Predictive Biomarker (PRD): MAD1L1 mRNA
Genes: MAD1L1; MAD1; TXBP181
Study 34024551 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32207067 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 32186107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32186107 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 32213768 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 36191758 — Surrogate Endpoint (SUR): Blood pressure
Study 33040101 — Surrogate Endpoint (SUR): Blood pressure
Study 32915972 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 32915972 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 32915972 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32915972 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 32943750 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 32943750 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 32943750 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 32943750 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 32943750 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33047455 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 33047455 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 35984171 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33693552 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33376568 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 35871088 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35560631 — Surrogate Endpoint (SUR): Blood pressure
Study 33984593 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 33984593 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 33984593 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 33984593 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 32702748 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 34494112 — Surrogate Endpoint (SUR): Blood pressure
Study 36228177 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33031175 — Surrogate Endpoint (SUR): Blood pressure
Study 36939661 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 32493344 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 32493344 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32493344 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 32493344 — Predictive Biomarker (PRD): PECAM1 mRNA
Genes: PECAM1
Study 32493344 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32493344 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 32493344 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 32493344 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 615261555 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 615261555 — Surrogate Endpoint (SUR): Blood pressure
Study 33876883 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35511285 — Surrogate Endpoint (SUR): Blood pressure
Study 35511285 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35511285 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33761625 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 34709659 — Predictive Biomarker (PRD): GNS mRNA
Genes: GNS
Study 35963491 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 36054285 — Predictive Biomarker (PRD): HBG1 mRNA
Genes: HBG1; PRO2979
Study 32447618 — Surrogate Endpoint (SUR): Blood pressure
Study 32640097 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 33651091 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 34248023 — Surrogate Endpoint (SUR): Serum calcium
Study 32578850 — Surrogate Endpoint (SUR): Blood pressure
Study 32578850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34800700 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34800700 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 34800700 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33314886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGB mRNA
Genes: FGB
Study 32790701 — Predictive Biomarker (PRD): SLC4A7 mRNA
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 32790701 — Surrogate Endpoint (SUR): Blood pressure
Study 35940551 — Surrogate Endpoint (SUR): Blood pressure
Study 36315419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36315419 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 35653145 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35653145 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35653145 — Predictive Biomarker (PRD): Hormone receptor
Study 36473717 — Surrogate Endpoint (SUR): Blood pressure
Study 35633027 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 32298662 — Predictive Biomarker (PRD): CES2 mRNA
Genes: CES2; ICE
Study 35351020 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 36208780 — Surrogate Endpoint (SUR): Blood pressure
Study 35930800 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35486613 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 35152576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35152576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33125518 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32271377 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 35561963 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 32025830 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 36172933 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34788822 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study 34788822 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 34757487 — Surrogate Endpoint (SUR): Blood pressure
Study 34083576 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 35328926 — Surrogate Endpoint (SUR): Blood pressure
Study 34539185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35881893 — Surrogate Endpoint (SUR): Blood pressure
Study 34303265 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 34303265 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 34303265 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32187913 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35678134 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 35678134 — Surrogate Endpoint (SUR): Blood pressure
Study 35260678 — Surrogate Endpoint (SUR): Serum creatinine
Study 33975993 — Surrogate Endpoint (SUR): Bone mineral density
Study 32533723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34167868 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 33721055 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33721055 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 33721055 — Predictive Biomarker (PRD): ARHGEF5 mRNA
Genes: ARHGEF5; TIM
Study 32305794 — Surrogate Endpoint (SUR): Blood pressure
Study 33453410 — Predictive Biomarker (PRD): AHNAK mRNA
Genes: AHNAK; PM227
Study 35460165 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 35460165 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 36399721 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 36399721 — Surrogate Endpoint (SUR): Blood pressure
Study 33302976 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 33302976 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35872955 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33359277 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 32729763 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 32690185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32690185 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 32690185 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32690185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32690185 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32245569 — Surrogate Endpoint (SUR): Serum creatinine
Study 34268883 — Surrogate Endpoint (SUR): Blood pressure
Study 32734356 — Surrogate Endpoint (SUR): Blood pressure
Study 33550668 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33550668 — Surrogate Endpoint (SUR): Serum creatinine
Study 33689732 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 36259531 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32909200 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 32535812 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32122618 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 34774725 — Surrogate Endpoint (SUR): Blood pressure
Study 33745627 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 32233107 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33091149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36283827 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33221392 — Surrogate Endpoint (SUR): Blood pressure
Study 36477032 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32749941 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 32749941 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study 32985001 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32869580 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 35441396 — Surrogate Endpoint (SUR): Bone mineral density
Study 33930795 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33930795 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35357766 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 36208364 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 32701172 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 34858404 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 32779505 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34377934 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 35616780 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 34388297 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33836364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32796950 — Predictive Biomarker (PRD): NRM mRNA
Genes: NRM; NRM29; UNQ555/PRO1112
Study 35064385 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 33796915 — Safety Biomarker (SAF): Prognostic nutrition index
Study 34922872 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32324592 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34698901 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 34698901 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 32635768 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 32635768 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35939311 — Surrogate Endpoint (SUR): Blood pressure
Study 32858063 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 32858063 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 32858063 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 35308069 — Surrogate Endpoint (SUR): Plasma ammonia
Study 33530512 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33530512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33530512 — Safety Biomarker (SAF): BDNF
Study 36442064 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33296278 — Surrogate Endpoint (SUR): Blood pressure
Study 34304881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 34076977 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33038899 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 33038899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36211709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36211709 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 36211709 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 36211709 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 34874418 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33315813 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32384509 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32384509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32384509 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32384509 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 32675334 — Predictive Biomarker (PRD): CPOX mRNA
Genes: CPOX; CPO; CPX
Study 35432581 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 35432581 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 35432581 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 35432581 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 32345594 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33906086 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34240656 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34887867 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 34887867 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34887867 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34887867 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 35637753 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 35637753 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 35637753 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 34029860 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34984845 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 34984845 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 35550459 — Surrogate Endpoint (SUR): Blood pressure
Study 34635855 — Predictive Biomarker (PRD): DGAT2 mRNA
Genes: DGAT2; HMFN1045; UNQ738/PRO1433
Study 34635855 — Surrogate Endpoint (SUR): Serum triglycerides
Study 35780807 — Predictive Biomarker (PRD): ATP8B1 mRNA
Genes: ATP8B1; ATPIC; FIC1; PFIC
Study 32590334 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 32467099 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 32467099 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34166373 — Safety Biomarker (SAF): Hyaluronic acid
Study 34477473 — Safety Biomarker (SAF): Hyaluronic acid
Study 34977961 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34977961 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 34977961 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32802264 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32302347 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32302347 — Safety Biomarker (SAF): BDNF
Study 32302709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33443879 — Safety Biomarker (SAF): Hyaluronic acid
Study 34371515 — Surrogate Endpoint (SUR): Serum creatinine
Study 35565656 — Predictive Biomarker (PRD): AXIN1 mRNA
Genes: AXIN1; AXIN
Study 35565656 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 35565656 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 35565656 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 35975308 — Surrogate Endpoint (SUR): Blood pressure
Study 34976328 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32249441 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 34641873 — Monitoring Biomarker (MOI): Cell-free DNA
Study 32535263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32535263 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 32535263 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34028550 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36458119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36458119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36458119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32576199 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 35202795 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 35857659 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35928098 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 35897381 — Predictive Biomarker (PRD): IVL mRNA
Genes: IVL
Study 32338106 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 33185468 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 33185468 — Surrogate Endpoint (SUR): Blood pressure
Study 32902413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32902413 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 33550905 — Safety Biomarker (SAF): MTHFR
Study 34095882 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32988903 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36274035 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2