TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35951718 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 35814746 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32178978 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35850080 — Surrogate Endpoint (SUR): Blood pressure
Study 32951632 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 35899378 — Predictive Biomarker (PRD): ICOSLG mRNA
Genes: ICOSLG; B7H2; B7RP1; ICOSL; KIAA0653
Study 35899378 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 35899378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32654554 — Surrogate Endpoint (SUR): Blood pressure
Study 32407137 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 35549845 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34951009 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 34951009 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 34951009 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 34951009 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 34719101 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 32350903 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32350903 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32350903 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32683755 — Monitoring Biomarker (MOI): Cell-free DNA
Study 32753452 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33827787 — Predictive Biomarker (PRD): IL17RA mRNA
Genes: IL17RA; IL17R
Study 33827787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33827787 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 32873573 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 33486528 — Surrogate Endpoint (SUR): Blood pressure
Study 34477931 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 34477931 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 34378669 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 36151869 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 35442482 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35442482 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 35593744 — Surrogate Endpoint (SUR): Serum uric acid
Study 35365457 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 32513245 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32513245 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34176274 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34176274 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35767699 — Predictive Biomarker (PRD): OGN mRNA
Genes: OGN; OIF; SLRR3A
Study 35767699 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 36134834 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33906043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33906043 — Safety Biomarker (SAF): Interleukin 1
Study 34708996 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 35319845 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 35319845 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 35843080 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 32268000 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 34081021 — Surrogate Endpoint (SUR): Blood pressure
Study 32029860 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 35057852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33443465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33443465 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33443465 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33443465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35933413 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 35933413 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35575988 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 33657293 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34611113 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 34611113 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 34611113 — Surrogate Endpoint (SUR): Blood pressure
Study 35661029 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32114892 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36042436 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 34274907 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 35807797 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 35807797 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study 35807797 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 36254732 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 34347008 — Surrogate Endpoint (SUR): Blood pressure
Study 34772982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34772982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34772982 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 34772982 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34772982 — Safety Biomarker (SAF): IL-6 and IL-10
Study 36110857 — Predictive Biomarker (PRD): KLRC2 mRNA
Genes: KLRC2; NKG2C
Study 36110857 — Predictive Biomarker (PRD): KLRC1 mRNA
Genes: KLRC1; NKG2A
Study 36110857 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 34375514 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32949011 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 32949011 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 33846075 — Surrogate Endpoint (SUR): Blood pressure
Study 35275541 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 36129996 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 36345917 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 32988520 — Predictive Biomarker (PRD): SREBF1 mRNA
Genes: SREBF1; BHLHD1; SREBP1
Study 32988520 — Predictive Biomarker (PRD): ACADL mRNA
Genes: ACADL
Study 32988520 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 32988520 — Predictive Biomarker (PRD): ELOVL5 mRNA
Genes: ELOVL5; ELOVL2; PRO0530
Study 36100282 — Predictive Biomarker (PRD): MAPK8IP1 mRNA
Genes: MAPK8IP1; IB1; JIP1; PRKM8IP
Study 33158949 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 35538630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33965506 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35026396 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32706859 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32481473 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32586932 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32586932 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35534349 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 34562202 — Surrogate Endpoint (SUR): Blood pressure
Study 33320406 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 35597332 — Surrogate Endpoint (SUR): Serum potassium
Study 36085879 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 616119517 — Predictive Biomarker (PRD): GMCL2 mRNA
Genes: GMCL2; GCL; GMCL1L; GMCL1P1
Study 35119467 — Surrogate Endpoint (SUR): Blood pressure
Study 32087600 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32514005 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 32514005 — Predictive Biomarker (PRD): ELOVL5 mRNA
Genes: ELOVL5; ELOVL2; PRO0530
Study 35452688 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33666322 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33666322 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 33666322 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 35090799 — Surrogate Endpoint (SUR): Blood pressure
Study 34204415 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 34204415 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 35082960 — Surrogate Endpoint (SUR): Blood pressure
Study 36254693 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33454241 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 33454241 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 33454241 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 33454241 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 36066851 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 33252241 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32330694 — Surrogate Endpoint (SUR): Bone mineral density
Study 34564020 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34237699 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33143164 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 33657762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32489807 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 33032710 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32200533 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 36215289 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35502503 — Predictive Biomarker (PRD): TFEB mRNA
Genes: TFEB; BHLHE35
Study 34535170 — Predictive Biomarker (PRD): TRIT1 mRNA
Genes: TRIT1; IPT; MOD5
Study 32306987 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 35938351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35122952 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 33924645 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35975641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34757917 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 34626757 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32574117 — Surrogate Endpoint (SUR): Serum creatinine
Study 35133671 — Surrogate Endpoint (SUR): Blood pressure
Study 33600460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32629112 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33421042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32334620 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 35045327 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32417946 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32417946 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32417946 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32417946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32417946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33812168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33812168 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 33812168 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 33812168 — Predictive Biomarker (PRD): VCAM1 mRNA
Genes: VCAM1
Study 36226089 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 36226089 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 36226089 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 33161293 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 32805185 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33966520 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33966520 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32633158 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 32633158 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 34006849 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 34006849 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 35708557 — Surrogate Endpoint (SUR): Blood pressure
Study 32209721 — Safety Biomarker (SAF): Interleukin 12
Study 32209721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32209721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32209721 — Safety Biomarker (SAF): Human leucocyte antigen
Study 32156479 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 32156479 — Surrogate Endpoint (SUR): Blood pressure
Study 32957418 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32957418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32778158 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 34133836 — Predictive Biomarker (PRD): SULT1A1 mRNA
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study 34850013 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34850013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34850013 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34850013 — Surrogate Endpoint (SUR): Blood pressure
Study 35269639 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 33939730 — Surrogate Endpoint (SUR): Blood pressure
Study 33183258 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 33183258 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35925043 — Surrogate Endpoint (SUR): Pathological complete response
Study 32139488 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 35083335 — Predictive Biomarker (PRD): PRG4 mRNA
Genes: PRG4; MSF; SZP
Study 35339911 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 35914303 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 33565403 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33565403 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32741216 — Safety Biomarker (SAF): miR-20b-5p
Genes: MIR20B
Study 32593895 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34353714 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 32171323 — Safety Biomarker (SAF): Interleukin 1
Study 32171323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34112615 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 36189651 — Safety Biomarker (SAF): Hyaluronic acid
Study 32351061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32351061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33556170 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 33556170 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 35583555 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 35583555 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35583555 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 35583555 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33682320 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 34499396 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 34182952 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 35381390 — Surrogate Endpoint (SUR): Bone mineral density
Study 34281641 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 32416181 — Surrogate Endpoint (SUR): Serum uric acid
Study 32416181 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 32416181 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32416181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35389963 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 35389963 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32142484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32142484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35312376 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 32045773 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 33930244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35134142 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 34647708 — Surrogate Endpoint (SUR): Blood pressure
Study 35003796 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 35241690 — Predictive Biomarker (PRD): CHGA mRNA
Genes: CHGA
Study 35677742 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33350891 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 32409696 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 33830082 — Predictive Biomarker (PRD): SOCS1 mRNA
Genes: SOCS1; SSI1; TIP3
Study 33830082 — Predictive Biomarker (PRD): CXCL2 mRNA
Genes: CXCL2; GRO2; GROB; MIP2A; SCYB2
Study 33830082 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 33645399 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 34894724 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 34894724 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34894724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34894724 — Surrogate Endpoint (SUR): Blood pressure
Study 34894724 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32344198 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 34170389 — Surrogate Endpoint (SUR): Serum asparaginase
Study 34232704 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 36217901 — Predictive Biomarker (PRD): DHODH mRNA
Genes: DHODH
Study 34192893 — Surrogate Endpoint (SUR): Blood pressure
Study 34192893 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35106590 — Surrogate Endpoint (SUR): Serum uric acid
Study 35106827 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 35106827 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 35857716 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 33956056 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 33272291 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33272291 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 33272291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33272291 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 33272291 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5