TrialPanorama/TrialPanorama-database huggingface dataset:
Study 34018147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34018147 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34901264 — Surrogate Endpoint (SUR): Blood pressure
Study 35397973 — Surrogate Endpoint (SUR): Blood pressure
Study 34473906 — Predictive Biomarker (PRD): GLB1L2 mRNA
Genes: GLB1L2; MSTP014; UNQ210/PRO236
Study 34473906 — Predictive Biomarker (PRD): BPIFB1 mRNA
Genes: BPIFB1; C20orf114; LPLUNC1; UNQ706/PRO1357
Study 34473906 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33780106 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 32902808 — Surrogate Endpoint (SUR): Blood pressure
Study 36350651 — Surrogate Endpoint (SUR): Blood pressure
Study 32916329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32522498 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 33822396 — Surrogate Endpoint (SUR): Blood pressure
Study 35739000 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 34719443 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 34719443 — Surrogate Endpoint (SUR): Blood pressure
Study 32706159 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32706159 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35876385 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34140596 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34140596 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 33781234 — Predictive Biomarker (PRD): PORCN mRNA
Genes: PORCN; MG61; PORC; PPN
Study 34365959 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 35718205 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34857710 — Surrogate Endpoint (SUR): Blood pressure
Study 33569809 — Surrogate Endpoint (SUR): Blood pressure
Study 33719268 — Predictive Biomarker (PRD): SDC1 mRNA
Genes: SDC1; SDC
Study 33719268 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 35737855 — Monitoring Biomarker (MOI): HBV DNA
Study 32737072 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32737072 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33549556 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study 33549556 — Predictive Biomarker (PRD): PAPPA mRNA
Genes: PAPPA
Study 33549556 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 33549556 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33549556 — Predictive Biomarker (PRD): RARRES2 mRNA
Genes: RARRES2; TIG2
Study 33549556 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 33549556 — Predictive Biomarker (PRD): RETN mRNA
Genes: RETN; FIZZ3; HXCP1; RSTN; UNQ407/PRO1199
Study 34879245 — Predictive Biomarker (PRD): OSTM1 mRNA
Genes: OSTM1; GL; HSPC019; UNQ6098/PRO21201
Study 32381018 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35610738 — Monitoring Biomarker (MOI): Complement C4
Study 34569981 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34569981 — Safety Biomarker (SAF): BDNF
Study 36056396 — Surrogate Endpoint (SUR): Bone mineral density
Study 32503030 — Surrogate Endpoint (SUR): Serum creatinine
Study 36069803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36069803 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 36069803 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34894070 — Surrogate Endpoint (SUR): Serum creatinine
Study 32811531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32811531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36202024 — Surrogate Endpoint (SUR): Blood pressure
Study 33793299 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33793299 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33793299 — Predictive Biomarker (PRD): Hormone receptor
Study 33793299 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33793299 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 33626934 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33626934 — Predictive Biomarker (PRD): LRIT1 mRNA
Genes: LRIT1; LRRC21; PAL
Study 33626934 — Predictive Biomarker (PRD): Hormone receptor
Study 34582171 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33280529 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 32660611 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 32520418 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 32520418 — Surrogate Endpoint (SUR): Blood pressure
Study 35197335 — Surrogate Endpoint (SUR): Blood pressure
Study 34788830 — Surrogate Endpoint (SUR): Blood pressure
Study 33630408 — Surrogate Endpoint (SUR): Blood pressure
Study 33630408 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 33515938 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 36459731 — Surrogate Endpoint (SUR): Blood pressure
Study 33675423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32048365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32048365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32048365 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 35238652 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 35238652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35238652 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 33027722 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 35732385 — Surrogate Endpoint (SUR): Blood pressure
Study 33121474 — Surrogate Endpoint (SUR): Blood pressure
Study 32902644 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 32987359 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 35159340 — Predictive Biomarker (PRD): TREM1 mRNA
Genes: TREM1
Study 34850952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33769862 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33769862 — Predictive Biomarker (PRD): Hormone receptor
Study 32659784 — Predictive Biomarker (PRD): HBEGF mRNA
Genes: HBEGF; DTR; DTS; HEGFL
Study 32324852 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 36348660 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36348660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33704806 — Predictive Biomarker (PRD): TLR8 mRNA
Genes: TLR8; UNQ249/PRO286
Study 34533059 — Surrogate Endpoint (SUR): Blood pressure
Study 34411738 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 32602616 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 35675469 — Surrogate Endpoint (SUR): Blood pressure
Study 33147721 — Surrogate Endpoint (SUR): Blood pressure
Study 36048358 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 36048358 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 33004126 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 35803552 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 34782535 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34782535 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32475050 — Surrogate Endpoint (SUR): Blood pressure
Study 34228273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34228273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34228273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35285922 — Surrogate Endpoint (SUR): Blood pressure
Study 36122531 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 32781940 — Surrogate Endpoint (SUR): Blood pressure
Study 36093154 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 34197181 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32782729 — Surrogate Endpoint (SUR): Blood pressure
Study 33993702 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33993702 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 35902075 — Surrogate Endpoint (SUR): Blood pressure
Study 35902075 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34326283 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 34326283 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 34326283 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 34326283 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34326283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34326283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34457024 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 36279134 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34633508 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35095912 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 32007694 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32799709 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36429935 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 32432684 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 32432684 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32432684 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32003649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32003649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32003649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34210154 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 34210154 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34210154 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 35651299 — Surrogate Endpoint (SUR): Blood pressure
Study 34241801 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 34488847 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 35500465 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 33833945 — Surrogate Endpoint (SUR): Blood pressure
Study 32794483 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 35732572 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 35810754 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 33957649 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 34454442 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32299852 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 32912410 — Surrogate Endpoint (SUR): Blood pressure
Study 36457354 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33999161 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 36213584 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33360345 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 33360345 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 33269553 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36471595 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 36471595 — Surrogate Endpoint (SUR): Blood pressure
Study 33079445 — Predictive Biomarker (PRD): GP1BA mRNA
Genes: GP1BA
Study 33079445 — Predictive Biomarker (PRD): BRAP mRNA
Genes: BRAP; RNF52
Study 32301407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33419890 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35124320 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35124320 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 35124320 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 35124320 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 35124320 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35124320 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 35124320 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 35124320 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 35124320 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 32819350 — Surrogate Endpoint (SUR): Blood pressure
Study 35796392 — Surrogate Endpoint (SUR): Serum antibody concentration
Study 33466246 — Safety Biomarker (SAF): Hyaluronic acid
Study 35101364 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35410238 — Surrogate Endpoint (SUR): Blood pressure
Study 33154284 — Surrogate Endpoint (SUR): Blood pressure
Study 35400298 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 34636974 — Monitoring Biomarker (MOI): Procalcitonin
Study 32777945 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34108397 — Surrogate Endpoint (SUR): Blood pressure
Study 32066726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34856936 — Surrogate Endpoint (SUR): Pathological complete response
Study 34163152 — Surrogate Endpoint (SUR): Blood pressure
Study 32706883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34482179 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34482179 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32280099 — Surrogate Endpoint (SUR): Probing pocket depth
Study 35960814 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 34919884 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 32087257 — Surrogate Endpoint (SUR): Serum creatinine
Study 35142559 — Surrogate Endpoint (SUR): Blood pressure
Study 32890573 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 35233908 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35233908 — Surrogate Endpoint (SUR): Blood pressure
Study 35233908 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33096684 — Surrogate Endpoint (SUR): Blood pressure
Study 33096684 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32092502 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 36336841 — Predictive Biomarker (PRD): OVOL2 mRNA
Genes: OVOL2; ZNF339
Study 33547945 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32493494 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34215316 — Surrogate Endpoint (SUR): Bone mineral density
Study 32641163 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32250503 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35678729 — Surrogate Endpoint (SUR): Blood pressure
Study 34689170 — Predictive Biomarker (PRD): TIPIN mRNA
Genes: TIPIN
Study 32283854 — Surrogate Endpoint (SUR): Blood pressure
Study 35667569 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 34449946 — Predictive Biomarker (PRD): BCL2L1 mRNA
Genes: BCL2L1; BCL2L; BCLX
Study 34449946 — Predictive Biomarker (PRD): GDF9 mRNA
Genes: GDF9
Study 36369901 — Predictive Biomarker (PRD): Microsatellite instability
Study 32580977 — Surrogate Endpoint (SUR): Blood pressure
Study 33318152 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 33210468 — Predictive Biomarker (PRD): ENTPD7 mRNA
Genes: ENTPD7; LALP1
Study 33210468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33210468 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33210468 — Predictive Biomarker (PRD): SELL mRNA
Genes: SELL; LNHR; LYAM1
Study 33685706 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 34302745 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32791501 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34116270 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 34116270 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34116270 — Predictive Biomarker (PRD): Hormone receptor
Study 32147076 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32990215 — Safety Biomarker (SAF): Glutamate dehydrogenase
Study 34959949 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 34959949 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 34959949 — Predictive Biomarker (PRD): EIF2AK2 mRNA
Genes: EIF2AK2; PKR; PRKR
Study 33642441 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 32127275 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 32683997 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 33213530 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34130022 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 33287816 — Monitoring Biomarker (MOI): HBV DNA
Study 34480412 — Surrogate Endpoint (SUR): Serum creatinine
Study 34543161 — Surrogate Endpoint (SUR): Serum potassium
Study 34445009 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33306565 — Monitoring Biomarker (MOI): HBV DNA
Study 32452181 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 35418312 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35418312 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 32008429 — Surrogate Endpoint (SUR): Blood pressure
Study 32932235 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 32932235 — Safety Biomarker (SAF): Interleukin 1
Study 35759537 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 34565292 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34565292 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34888401 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 37914510 — Surrogate Endpoint (SUR): Blood pressure
Study 32467339 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 32639468 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 34066577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34536050 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32296931 — Surrogate Endpoint (SUR): Blood pressure
Study 35618550 — Surrogate Endpoint (SUR): Blood pressure
Study 32280089 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 33246408 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 33871159 — Predictive Biomarker (PRD): SCAI mRNA
Genes: SCAI; C9orf126
Study 33001556 — Predictive Biomarker (PRD): GLP1R mRNA
Genes: GLP1R
Study 33001556 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34102077 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 33310204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33653802 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36145067 — Surrogate Endpoint (SUR): Blood pressure
Study 34560444 — Surrogate Endpoint (SUR): Blood pressure
Study 34385364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34597384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34597384 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34597384 — Surrogate Endpoint (SUR): Serum testosterone
Study 32335270 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 32335270 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 32335270 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 32335270 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32335270 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36309846 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 35303782 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 35303782 — Predictive Biomarker (PRD): Hormone receptor
Study 35303782 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF