TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35620203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35351196 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 34043103 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33485468 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32859334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32859334 — Surrogate Endpoint (SUR): Blood pressure
Study 616701079 — Surrogate Endpoint (SUR): Blood pressure
Study 34600589 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34600589 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33197226 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32345730 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 32172171 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 34268773 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34564755 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 32555695 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 33787041 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33787041 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33787041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32470975 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 32470975 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 35857130 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 35857130 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 35857130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32513564 — Predictive Biomarker (PRD): DPEP3 mRNA
Genes: DPEP3; UNQ834/PRO1772
Study 34699852 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34699852 — Surrogate Endpoint (SUR): Blood pressure
Study 34043117 — Safety Biomarker (SAF): Hyaluronic acid
Study 32043302 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 32043302 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32043302 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 36255239 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 36245883 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 32079623 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study 32079623 — Predictive Biomarker (PRD): Microsatellite instability
Study 33847683 — Surrogate Endpoint (SUR): Blood pressure
Study 32334045 — Safety Biomarker (SAF): MTHFR
Study 35377948 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 35377948 — Predictive Biomarker (PRD): CXCR5 mRNA
Genes: CXCR5; BLR1; MDR15
Study 35377948 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): GZMB mRNA
Genes: GZMB; CGL1; CSPB; CTLA1; GRB
Study 35377948 — Predictive Biomarker (PRD): CD79A mRNA
Genes: CD79A; IGA; MB1
Study 35377948 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 35377948 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35377948 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 33197078 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 34398258 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33153310 — Safety Biomarker (SAF): Hyaluronic acid
Study 33288437 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 35577646 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 35577646 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study 35577646 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 32000750 — Surrogate Endpoint (SUR): Blood pressure
Study 36200936 — Surrogate Endpoint (SUR): Bone mineral density
Study 34533197 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33817998 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 36099704 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 32680773 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34053490 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32327444 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32327444 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 36027721 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 33811746 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 33811746 — Predictive Biomarker (PRD): MGAM mRNA
Genes: MGAM; MGA; MGAML
Study 33811746 — Predictive Biomarker (PRD): RAD51B mRNA
Genes: RAD51B; RAD51L1; REC2
Study 33811746 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 33811746 — Predictive Biomarker (PRD): MECOM mRNA
Genes: MECOM; EVI1; MDS1; PRDM3
Study 33811746 — Predictive Biomarker (PRD): ANTXR1 mRNA
Genes: ANTXR1; ATR; TEM8
Study 33811746 — Predictive Biomarker (PRD): PARP4 mRNA
Genes: PARP4; ADPRTL1; KIAA0177; PARPL
Study 33811746 — Predictive Biomarker (PRD): C11orf30
Genes: EMSY
Study 32150263 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32150263 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 33002436 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32320373 — Predictive Biomarker (PRD): FER mRNA
Genes: FER; TYK3
Study 32810553 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 32810553 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 35840067 — Safety Biomarker (SAF): Hyaluronic acid
Study 34156335 — Surrogate Endpoint (SUR): Blood pressure
Study 33492018 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32543155 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 34620658 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34620658 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32429917 — Surrogate Endpoint (SUR): Blood pressure
Study 32111579 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 35477363 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 34606319 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35078280 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32928528 — Predictive Biomarker (PRD): FER mRNA
Genes: FER; TYK3
Study 35166728 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 35166728 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 34883506 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 35442223 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34256800 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32087025 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 34699693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34471000 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32755526 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36216140 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 37779358 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33581774 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33581774 — Predictive Biomarker (PRD): Hormone receptor
Study 34953401 — Surrogate Endpoint (SUR): Serum creatinine
Study 33103603 — Surrogate Endpoint (SUR): Blood pressure
Study 32209625 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 32965395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32965395 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32965395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32965395 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32228177 — Surrogate Endpoint (SUR): Serum uric acid
Study 35213547 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33179398 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 36476193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34798266 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 35340172 — Surrogate Endpoint (SUR): Pathological complete response
Study 34511134 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 34162512 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32522060 — Surrogate Endpoint (SUR): Blood pressure
Study 32372407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33874800 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32460589 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33645192 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 34853089 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 32510144 — Surrogate Endpoint (SUR): Blood pressure
Study 32510144 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32510144 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 36008059 — Predictive Biomarker (PRD): TYRO3 mRNA
Genes: TYRO3; BYK; DTK; RSE; SKY; TIF
Study 36252683 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36252683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36252683 — Safety Biomarker (SAF): BDNF
Study 32880201 — Surrogate Endpoint (SUR): Bone mineral density
Study 36374656 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35892316 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 35892316 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 35892316 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 35350100 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32993799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32993799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34708929 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32196976 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 35023346 — Surrogate Endpoint (SUR): Blood pressure
Study 34981479 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 33239135 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 33239135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33980691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32925788 — Surrogate Endpoint (SUR): Bone mineral density
Study 34076288 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 34076288 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32176744 — Predictive Biomarker (PRD): ERF mRNA
Genes: ERF
Study 36014880 — Safety Biomarker (SAF): Reactive oxygen species
Study 36014880 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 34336888 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 34281854 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 34281854 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33506810 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33595663 — Surrogate Endpoint (SUR): Blood pressure
Study 32045638 — Predictive Biomarker (PRD): LYZ mRNA
Genes: LYZ; LZM
Study 32045638 — Safety Biomarker (SAF): Reactive oxygen species
Study 32045638 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 631198356 — Surrogate Endpoint (SUR): Blood pressure
Study 35258510 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 32264972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32264972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32264972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32264972 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 33301475 — Predictive Biomarker (PRD): ZPR1 mRNA
Genes: ZPR1; ZNF259
Study 33081083 — Predictive Biomarker (PRD): OR2AG2 mRNA
Genes: OR2AG2; OR2AG2P
Study 33081083 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 34311777 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32273054 — Surrogate Endpoint (SUR): Serum creatinine
Study 32722956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32722956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35437302 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 34308962 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 34308962 — Predictive Biomarker (PRD): IL10RB mRNA
Genes: IL10RB; CRFB4; D21S58; D21S66
Study 34308962 — Predictive Biomarker (PRD): TNFSF15 mRNA
Genes: TNFSF15; TL1; VEGI
Study 33370962 — Safety Biomarker (SAF): MTHFR
Study 34114615 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34114615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34546360 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 34584203 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 34584203 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34584203 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study 32370765 — Monitoring Biomarker (MOI): Cell-free DNA
Study 34098771 — Surrogate Endpoint (SUR): Serum creatinine
Study 34098771 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 34098771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34098771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34293127 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34293127 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 34293127 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 32162310 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 35603908 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33812487 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34613338 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 33091586 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34444682 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 34444682 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 33108030 — Surrogate Endpoint (SUR): Blood pressure
Study 36241889 — Surrogate Endpoint (SUR): Bacterial count
Study 32960145 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32812021 — Safety Biomarker (SAF): Interleukin 1
Study 34392331 — Surrogate Endpoint (SUR): Blood pressure
Study 35695863 — Predictive Biomarker (PRD): FOXM1 mRNA
Genes: FOXM1; FKHL16; HFH11; MPP2; WIN
Study 32079999 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 32079999 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 35608600 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34628738 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34628738 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36428227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36428227 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32683106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32683106 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35042290 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 32867226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32403259 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36346619 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 35067753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32239091 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 32239091 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study 32581042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32581042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34491805 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 34016554 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 35471480 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35471480 — Surrogate Endpoint (SUR): Serum creatinine
Study 35706460 — Safety Biomarker (SAF): Interleukin 1
Study 33555464 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 34813505 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 34813505 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32671948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33662166 — Surrogate Endpoint (SUR): Blood pressure
Study 34563558 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32583773 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32384426 — Predictive Biomarker (PRD): SLC26A4 mRNA
Genes: SLC26A4; PDS
Study 32667956 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 34282872 — Safety Biomarker (SAF): Hyaluronic acid
Study 33334875 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33334875 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 34476645 — Predictive Biomarker (PRD): CXCR1 mRNA
Genes: CXCR1; CMKAR1; IL8RA
Study 34476645 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 34476645 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study 34476645 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 33930329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34555048 — Surrogate Endpoint (SUR): Probing pocket depth
Study 34554352 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35689904 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 32725799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35289296 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35289296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34200105 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 33262202 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 33262202 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33739155 — Surrogate Endpoint (SUR): Serum testosterone
Study 35300378 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34081901 — Predictive Biomarker (PRD): ATF3 mRNA
Genes: ATF3
Study 35220313 — Safety Biomarker (SAF): miR-652
Genes: MIR652
Study 35220313 — Predictive Biomarker (PRD): miR-106b
Genes: MIR106B
Study 35220313 — Safety Biomarker (SAF): miR-93-5p
Genes: MIR93
Study 35220313 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study 35220313 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 35526530 — Surrogate Endpoint (SUR): Blood pressure
Study 33780940 — Surrogate Endpoint (SUR): Serum sodium
Study 32855069 — Surrogate Endpoint (SUR): Blood pressure
Study 35982326 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 33823907 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32915900 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 36178918 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 32819960 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 34037885 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34923903 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34369667 — Predictive Biomarker (PRD): ROBO2 mRNA
Genes: ROBO2; KIAA1568
Study 34369667 — Predictive Biomarker (PRD): SLIT2 mRNA
Genes: SLIT2; SLIL3