TrialPanorama/TrialPanorama-database huggingface dataset:
Study 38458016 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 38458039 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 38458039 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 38458558 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 38458560 — Surrogate Endpoint (SUR): Blood pressure
Study 38458635 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38458639 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 38458639 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 38458639 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): GZMB mRNA
Genes: GZMB; CGL1; CSPB; CTLA1; GRB
Study 38458816 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 38458816 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 38459254 — Predictive Biomarker (PRD): CPQ mRNA
Genes: CPQ; LCH1; PGCP
Study 38459338 — Predictive Biomarker (PRD): TNIK mRNA
Genes: TNIK; KIAA0551
Study 38459552 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 38459585 — Predictive Biomarker (PRD): ALPL mRNA
Genes: ALPL
Study 38459585 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 38459598 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38460070 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 38460070 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 38460070 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 38460092 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 38460548 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 38461323 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38461480 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 38462613 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38462613 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 38462919 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 38463677 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 38466302 — Surrogate Endpoint (SUR): Blood pressure
Study 38467131 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 38467379 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 38467760 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 38467912 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38467918 — Surrogate Endpoint (SUR): Blood pressure
Study 38468231 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38468231 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 38468231 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38468231 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 38468241 — Surrogate Endpoint (SUR): Serum uric acid
Study 38468259 — Predictive Biomarker (PRD): HOXB2 mRNA
Genes: HOXB2; HOX2H
Study 38468259 — Predictive Biomarker (PRD): ELF3 mRNA
Genes: ELF3; ERT; ESX; JEN
Study 38468338 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 38468418 — Surrogate Endpoint (SUR): Blood pressure
Study 38468620 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 38469548 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 38470420 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38470447 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38470447 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38470447 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 38470447 — Predictive Biomarker (PRD): Hormone receptor
Study 38471825 — Safety Biomarker (SAF): Interleukin 1
Study 38472696 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 38472696 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 38473239 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 38473239 — Predictive Biomarker (PRD): FCGR3A
Genes: CD16; CD16a; FcgammaRIIIa; FcGRIIIA
Study 38473239 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 38473248 — Monitoring Biomarker (MOI): HBV DNA
Study 38475751 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 38475764 — Safety Biomarker (SAF): Hyaluronic acid
Study 38475786 — Safety Biomarker (SAF): Interleukin 1
Study 38475786 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 38475822 — Predictive Biomarker (PRD): DPP3 mRNA
Genes: DPP3
Study 38475822 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 38476120 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 38476213 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 38477966 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 38477985 — Monitoring Biomarker (MOI): Cell-free DNA
Study 38477987 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 38477987 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 38478488 — Surrogate Endpoint (SUR): Serum potassium
Study 38478535 — Predictive Biomarker (PRD): ABCG5 mRNA
Genes: ABCG5
Study 38478535 — Predictive Biomarker (PRD): ABCG8 mRNA
Genes: ABCG8
Study 38478535 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 38478535 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 38478535 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 38478535 — Predictive Biomarker (PRD): LIPA mRNA
Genes: LIPA
Study 38478535 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 38478705 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 38479118 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 38479751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38479820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38479953 — Surrogate Endpoint (SUR): Serum creatinine
Study 38480590 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 38480632 — Surrogate Endpoint (SUR): Blood pressure
Study 38480922 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 38481208 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 38481209 — Predictive Biomarker (PRD): RAPH1 mRNA
Genes: RAPH1; ALS2CR18; ALS2CR9; KIAA1681; LPD; PREL2; RMO1
Study 38481211 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 38481504 — Surrogate Endpoint (SUR): Urinary oxalate
Study 38481666 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 38481666 — Surrogate Endpoint (SUR): Serum testosterone
Study 38481947 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 38481947 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study 38481947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 38481947 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 38482462 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 38483248 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 38483248 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 38483248 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 38483412 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 38483732 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 38483732 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 38483782 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 38484130 — Safety Biomarker (SAF): c-Jun N-terminal kinase
Study 38484209 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 38484209 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 38485054 — Surrogate Endpoint (SUR): Blood pressure
Study 38485184 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38485184 — Predictive Biomarker (PRD): Microsatellite instability
Study 38485475 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 38486179 — Surrogate Endpoint (SUR): Blood pressure
Study 38486776 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 38487528 — Safety Biomarker (SAF): Interleukin 12
Study 38487573 — Surrogate Endpoint (SUR): Blood pressure
Study 38487818 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 38487818 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 38487818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38488429 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 38488429 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38488975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38489119 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38489667 — Predictive Biomarker (PRD): COG7 mRNA
Genes: COG7; UNQ3082/PRO10013
Study 38489667 — Predictive Biomarker (PRD): DCTN5 mRNA
Genes: DCTN5
Study 38490697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38491190 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 38491190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38491364 — Predictive Biomarker (PRD): CAPN3 mRNA
Genes: CAPN3; CANP3; CANPL3; NCL1
Study 38491364 — Predictive Biomarker (PRD): ANO5 mRNA
Genes: ANO5; GDD1; TMEM16E
Study 38491364 — Predictive Biomarker (PRD): DYSF mRNA
Genes: DYSF; FER1L1
Study 38491364 — Predictive Biomarker (PRD): DNAJB6 mRNA
Genes: DNAJB6; HSJ2; MRJ; MSJ1
Study 38491364 — Predictive Biomarker (PRD): SGCA mRNA
Genes: SGCA; ADL; DAG2
Study 38491364 — Predictive Biomarker (PRD): SGCB mRNA
Genes: SGCB
Study 38491364 — Predictive Biomarker (PRD): SGCD mRNA
Genes: SGCD
Study 38491364 — Predictive Biomarker (PRD): SGCG mRNA
Genes: SGCG
Study 38491364 — Predictive Biomarker (PRD): FKRP mRNA
Genes: FKRP
Study 38491429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38491540 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 38491795 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 38491965 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 38492078 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 38492157 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 38492667 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 38493021 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study 38493021 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 38493021 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 38493021 — Predictive Biomarker (PRD): PTK2B mRNA
Genes: PTK2B; FAK2; PYK2; RAFTK
Study 38493021 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 38493832 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 38493832 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 38493909 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 38493953 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 38494380 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 38494412 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 38494525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38496326 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38496619 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 38497241 — Surrogate Endpoint (SUR): Serum potassium
Study 38497987 — Surrogate Endpoint (SUR): Blood pressure
Study 38498140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38498512 — Predictive Biomarker (PRD): SLC25A3 mRNA
Genes: SLC25A3; PHC; OK/SW-cl.48
Study 38498587 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 38498623 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 38498781 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 38498934 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 38499238 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 38499238 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 38500184 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 38500476 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 38501187 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 38501219 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study 38501219 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 38501690 — Predictive Biomarker (PRD): DUT mRNA
Genes: DUT
Study 38501751 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 38501946 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 38501946 — Safety Biomarker (SAF): Reactive oxygen species
Study 38502126 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 38502193 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 38502193 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 38502193 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 38502195 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 38502198 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 38502672 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 38502995 — Predictive Biomarker (PRD): TACSTD2 mRNA
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study 38502995 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38502995 — Predictive Biomarker (PRD): Hormone receptor
Study 38503386 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 38503417 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 38503755 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 38503755 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38503990 — Surrogate Endpoint (SUR): Blood pressure
Study 38504015 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 38504173 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38504186 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 38504437 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 38505522 — Surrogate Endpoint (SUR): Bone mineral density
Study 38505928 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 38506710 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38506900 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 38506900 — Surrogate Endpoint (SUR): Sperm parameters
Study 38507441 — Surrogate Endpoint (SUR): Blood pressure
Study 38507688 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 38507688 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 38507751 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38507751 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38507751 — Predictive Biomarker (PRD): Hormone receptor
Study 38507976 — Surrogate Endpoint (SUR): Blood pressure
Study 38508239 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 38508334 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 38508334 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 38508844 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 38508877 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 38508877 — Surrogate Endpoint (SUR): Blood pressure
Study 38508877 — Surrogate Endpoint (SUR): Serum potassium
Study 38508975 — Predictive Biomarker (PRD): COL17A1 mRNA
Genes: COL17A1; BP180; BPAG2
Study 38509415 — Surrogate Endpoint (SUR): Blood pressure
Study 38509514 — Surrogate Endpoint (SUR): Blood pressure
Study 38509517 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 38509699 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 38510323 — Predictive Biomarker (PRD): AWAT2 mRNA
Genes: AWAT2; DC4; DGAT2L4; MFAT; WS
Study 38510502 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 38510574 — Surrogate Endpoint (SUR): Blood pressure
Study 38510748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38510748 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 38510748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38510983 — Monitoring Biomarker (MOI): HBV DNA
Study 38511555 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38511555 — Monitoring Biomarker (MOI): HBV DNA
Study 38511563 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 38512333 — Surrogate Endpoint (SUR): Blood pressure
Study 38512694 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 38512960 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 38513188 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 38513188 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38513188 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38513188 — Predictive Biomarker (PRD): Hormone receptor
Study 38513321 — Surrogate Endpoint (SUR): Blood pressure
Study 38513368 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 38513436 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 38513888 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 38513982 — Predictive Biomarker (PRD): NDRG4 mRNA
Genes: NDRG4; BDM1; KIAA1180
Study 38513982 — Predictive Biomarker (PRD): VAV3 mRNA
Genes: VAV3
Study 38513982 — Predictive Biomarker (PRD): ZNF682 mRNA
Genes: ZNF682
Study 38514081 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38514306 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38514519 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 38514823 — Surrogate Endpoint (SUR): Blood pressure
Study 38515149 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCNE2 mRNA
Genes: CCNE2
Study 38515149 — Predictive Biomarker (PRD): USP10 mRNA
Genes: USP10; KIAA0190
Study 38515149 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 38515183 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38515201 — Surrogate Endpoint (SUR): Blood pressure
Study 38515570 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 38515570 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38516100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38516100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 38516100 — Safety Biomarker (SAF): Interleukin 1
Study 38516100 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 38517242 — Predictive Biomarker (PRD): SLBP mRNA
Genes: SLBP; HBP
Study 38517242 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 38517416 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38517416 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38518104 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 38518104 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 38518104 — Predictive Biomarker (PRD): STIL mRNA
Genes: STIL; SIL
Study 38518104 — Predictive Biomarker (PRD): TAL1 mRNA
Genes: TAL1; BHLHA17; SCL; TCL5
Study 38518104 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 38518104 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 38518104 — Predictive Biomarker (PRD): PTPN2 mRNA
Genes: PTPN2; PTPT
Study 38518104 — Predictive Biomarker (PRD): RPL22 mRNA
Genes: RPL22
Study 38518104 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 38518848 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38518848 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 38519053 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 38519055 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 38519055 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 38519055 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 38519416 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 38519581 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 38519913 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38519913 — Predictive Biomarker (PRD): IRF1 mRNA
Genes: IRF1
Study 38519913 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 38519913 — Safety Biomarker (SAF): C-C motif chemokine 19
Genes: CCL19; ELC; MIP3B; SCYA19
Study 38519913 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 38519913 — Predictive Biomarker (PRD): MACF1 mRNA
Genes: MACF1; KIAA0754