TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05718882 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT06326983 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04490720 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06280742 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT06540573 — Predictive Biomarker (PRD): CCL21 mRNA
Genes: CCL21; SCYA21; UNQ784/PRO1600
Study NCT06540573 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study NCT05019118 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT04960839 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04960839 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT04960839 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT05317780 — Predictive Biomarker (PRD): ASPA mRNA
Genes: ASPA; ACY2; ASP
Study NCT05416359 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05503264 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study NCT06272812 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT05256004 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study NCT04928898 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05412446 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06443645 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06443645 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05240430 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT06497361 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06497361 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04670627 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT04670627 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT04670627 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT05631379 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT05631379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05631379 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT05631379 — Safety Biomarker (SAF): Platelet to lymphocyte
Study NCT05631379 — Safety Biomarker (SAF): Prognostic nutrition index
Study NCT05099367 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study NCT05099367 — Predictive Biomarker (PRD): PTGIS mRNA
Genes: PTGIS; CYP8; CYP8A1
Study NCT06108674 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05858190 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05096572 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study NCT05885529 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT04827667 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05057572 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT05352633 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06356233 — Predictive Biomarker (PRD): STXBP1 mRNA
Genes: STXBP1; UNC18A
Study NCT05631912 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05631912 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study NCT05833828 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT05833828 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05375279 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT06081959 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06081959 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05375084 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04843722 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05241899 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04475705 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT05009901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05009901 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT05467670 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study NCT05260918 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study NCT04590833 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04590833 — Safety Biomarker (SAF): BDNF
Study NCT06098638 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05034900 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05898776 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT06394921 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05743686 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05743686 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05743686 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04731155 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04905277 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05739084 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT05473221 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT06365970 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04786067 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04662294 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT04810702 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT06567470 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study NCT05574855 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT05574855 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT04657224 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04633902 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06427122 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT05876403 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05047250 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05047250 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05158855 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06032013 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05292469 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06292806 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT05327023 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06478381 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05497531 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04847102 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06106893 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06413316 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study NCT06726785 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT05107960 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06730581 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT05604378 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05604378 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT05604378 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05604378 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT05604378 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT06246006 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study NCT06246006 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT05827471 — Predictive Biomarker (PRD): QSOX1 mRNA
Genes: QSOX1; QSCN6; UNQ2520/PRO6013
Study NCT06731790 — Predictive Biomarker (PRD): RANBP2 mRNA
Genes: RANBP2; NUP358
Study NCT05342428 — Predictive Biomarker (PRD): TLL1 mRNA
Genes: TLL1; TLL
Study NCT03943927 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT06126016 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT05402826 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04953481 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT06434792 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05836298 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06342180 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT05762510 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05058183 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05785221 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05182931 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT05916586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06539091 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT06539091 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05101356 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05785819 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study NCT05117931 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05117931 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05262933 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05816044 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00002338 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05883020 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study NCT06566066 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04908956 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05027009 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT05761132 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05761132 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05761132 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study NCT06182657 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT06222944 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT05111418 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT06509776 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05347082 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00000891 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study NCT06182735 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT05215366 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT05215366 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT05215548 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05215548 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06368882 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05801640 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05721638 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT05721638 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05075044 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06309472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06309472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05213247 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04873492 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00017940 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT05479903 — Safety Biomarker (SAF): BDNF
Study NCT05233384 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study NCT05233384 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGB mRNA
Genes: FGB
Study NCT05233384 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study NCT05233384 — Safety Biomarker (SAF): Coagulation factor Va
Genes: F5
Study NCT05233384 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study NCT05233384 — Predictive Biomarker (PRD): PROCR mRNA
Genes: PROCR; EPCR
Study NCT06009809 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00000774 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06330220 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06330220 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05007353 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05825690 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study NCT05037552 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT05900206 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06503315 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT04895228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04895228 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT05011097 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT06454370 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study NCT06548139 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06723015 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06745011 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT05307198 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06474520 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study NCT05980416 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT06761612 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06764017 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT06764017 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT04800770 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT06053125 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study NCT05730803 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study NCT06764836 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06083701 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT05710679 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05595408 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04882345 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06764381 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06764303 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study NCT05812391 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT05812391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05753501 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05676476 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05693545 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study NCT06438679 — Predictive Biomarker (PRD): IFIH1 mRNA
Genes: IFIH1; MDA5; RH116
Study NCT06592989 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06592989 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06592989 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study NCT06592989 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06592989 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06764329 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04886271 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study NCT06657222 — Predictive Biomarker (PRD): TPBG mRNA
Genes: TPBG; 5T4
Study NCT06657222 — Predictive Biomarker (PRD): TUB mRNA
Genes: TUB
Study NCT06176365 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06176365 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05679206 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05030727 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT05030727 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06295575 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06138249 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05459532 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05092204 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study NCT05092204 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06229392 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05311644 — Predictive Biomarker (PRD): VIT mRNA
Genes: VIT; UNQ647/PRO1277
Study NCT04947813 — Predictive Biomarker (PRD): COL4A3 mRNA
Genes: COL4A3
Study NCT04947813 — Predictive Biomarker (PRD): COL4A4 mRNA
Genes: COL4A4
Study NCT04947813 — Predictive Biomarker (PRD): COL4A5 mRNA
Genes: COL4A5
Study NCT05223595 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04850560 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT04850560 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04750460 — Surrogate Endpoint (SUR): Serum calcium
Study NCT06327724 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT05716672 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04653493 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06177366 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT05936905 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT06038578 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT00061256 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06137534 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00000943 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05760326 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT05760326 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT05760326 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study NCT05760326 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05760326 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05760326 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT04745949 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT05809713 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04753892 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05337826 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study NCT03706573 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03706573 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05434845 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT06374043 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06374043 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04891640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05818683 — Predictive Biomarker (PRD): KLK2 mRNA
Genes: KLK2
Study NCT06443606 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT04832100 — Predictive Biomarker (PRD): ASIC3 mRNA
Genes: ASIC3; ACCN3; SLNAC1; TNAC1
Study NCT04672382 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT05771883 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT05440994 — Predictive Biomarker (PRD): PLA2G6 mRNA
Genes: PLA2G6; PLPLA9
Study NCT05536388 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study NCT04646564 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04591990 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT04908111 — Predictive Biomarker (PRD): MAGEA3 mRNA
Genes: MAGEA3; MAGE3
Study NCT00001068 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05728814 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04498325 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04835714 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05077696 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study NCT06355843 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04836221 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06428890 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06318208 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04988698 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06550167 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06550167 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06550167 — Safety Biomarker (SAF): Reactive oxygen species