TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05579184 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05360537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05360537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05774262 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT05664971 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study NCT06340984 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT05667441 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04704440 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT04834830 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04834830 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04834830 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study NCT04834830 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT04834830 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT04901416 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05914285 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT06377137 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06377137 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06377137 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06282926 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT05556200 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT04598646 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT06401590 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT04926259 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05466786 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05466786 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT04288869 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05438875 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05438875 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study NCT05260437 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06104670 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT04927715 — Predictive Biomarker (PRD): FNDC5 mRNA
Genes: FNDC5; FRCP2
Study NCT06254976 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study NCT05200624 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05667935 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT04478409 — Predictive Biomarker (PRD): MEFV mRNA
Genes: MEFV; MEF; TRIM20
Study NCT06505356 — Predictive Biomarker (PRD): JAZF1 mRNA
Genes: JAZF1; TIP27; ZNF802
Study NCT06170125 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT05396885 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT00478127 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT06168045 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06422598 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06099444 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT05139615 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06456359 — Predictive Biomarker (PRD): SSTR2 mRNA
Genes: SSTR2
Study NCT06456359 — Predictive Biomarker (PRD): SSTR3 mRNA
Genes: SSTR3
Study NCT06456359 — Predictive Biomarker (PRD): SSTR5 mRNA
Genes: SSTR5
Study NCT06456359 — Predictive Biomarker (PRD): SSTR1 mRNA
Genes: SSTR1
Study NCT05073822 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05156606 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02500082 — Predictive Biomarker (PRD): SLC13A5 mRNA
Genes: SLC13A5; NACT
Study NCT06465537 — Predictive Biomarker (PRD): MYOC mRNA
Genes: MYOC; GLC1A; TIGR
Study NCT05033756 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT05033756 — Predictive Biomarker (PRD): BARD1 mRNA
Genes: BARD1
Study NCT05033756 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study NCT05033756 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT05033756 — Predictive Biomarker (PRD): RAD51C mRNA
Genes: RAD51C; RAD51L2
Study NCT05033756 — Predictive Biomarker (PRD): SLX4 mRNA
Genes: SLX4; BTBD12; KIAA1784; KIAA1987
Study NCT05033756 — Predictive Biomarker (PRD): XRCC2 mRNA
Genes: XRCC2
Study NCT05033756 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT05033756 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT05573217 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT05573217 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04994093 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT06165523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05691400 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03422705 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03422705 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05205083 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05116306 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06470633 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06470633 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05962099 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study NCT05962099 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04920968 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04842006 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05905068 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT05905068 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04912765 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04108858 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04108858 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT04108858 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT06462248 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06154161 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT05427942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05232357 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT05054751 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05054751 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06026202 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT06043076 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05326685 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04447898 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04447898 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03975361 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT06455072 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06455072 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06509555 — Predictive Biomarker (PRD): TK1 mRNA
Genes: TK1
Study NCT05026827 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT05778253 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05371899 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04518306 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06084988 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT06084988 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04981431 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05629806 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT05686837 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT05020236 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05020236 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT06504719 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06404983 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06327997 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT05500261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05500261 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05790317 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT05208788 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT05208788 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT05208788 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study NCT05208788 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05208788 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT05537935 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04703114 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04624906 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04081818 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06307574 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06277206 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05942664 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03145545 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05453435 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT05452356 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05848856 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00001998 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study NCT05496829 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05425498 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06022198 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05739409 — Predictive Biomarker (PRD): LILRB4 mRNA
Genes: LILRB4; ILT3; LIR5
Study NCT02025712 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06119802 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT05793489 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT05847114 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05112770 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study NCT05112770 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study NCT06091969 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT05871788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05871788 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study NCT05871788 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT05871788 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT05871788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05871788 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04916704 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study NCT04916704 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT05126537 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study NCT05126537 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study NCT05193526 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04733417 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04733417 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04733417 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05813522 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05661240 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05049265 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04828915 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06503991 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00749827 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT00749827 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00749827 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT05201625 — Safety Biomarker (SAF): CD177 antigen
Genes: CD177; NB1; PRV1; UNQ595/PRO1181
Study NCT05781932 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT06011057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05080556 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT05180175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05804734 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT05228834 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03810911 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05143320 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05121376 — Predictive Biomarker (PRD): SERPING1 mRNA
Genes: SERPING1; C1IN; C1NH
Study NCT05748808 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06720441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06720441 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT06080802 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05689424 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT06386354 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT05396573 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05410717 — Predictive Biomarker (PRD): CLDN6 mRNA
Genes: CLDN6; UNQ757/PRO1488
Study NCT05410717 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT05410717 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT04636515 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01255267 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01255267 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT04971902 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT06473194 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04634994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04634994 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study NCT05577442 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05577442 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06211998 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01336907 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00311545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06298747 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study NCT05193175 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05193175 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05193175 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04804371 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT05067816 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06464666 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06411054 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05726994 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT05053035 — Pharmacodynamic Biomarker (PDY): Guanine nucleotide exchange factor C9orf72
Genes: C9orf72; DENND9; DENNL72
Study NCT05253066 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05253066 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06315972 — Predictive Biomarker (PRD): CA4 mRNA
Genes: CA4
Study NCT05538949 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT06196294 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT05751720 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT05029089 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT05060445 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT06602128 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06606769 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05534516 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06305910 — Predictive Biomarker (PRD): CD200 mRNA
Genes: CD200; MOX1; MOX2; My033
Study NCT05034237 — Surrogate Endpoint (SUR): Bacterial count
Study NCT06019715 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06420752 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06053983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05516511 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05486988 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05291546 — Predictive Biomarker (PRD): NPR1 mRNA
Genes: NPR1; ANPRA
Study NCT06337799 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05760417 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06581887 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06581887 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study NCT05547919 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03981640 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05771402 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02529735 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06068257 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study NCT04906759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04906759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04906759 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT04906759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04745910 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT05351788 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study NCT05501340 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06022003 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT04851288 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04851288 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05809635 — Predictive Biomarker (PRD): BEST1 mRNA
Genes: BEST1; VMD2
Study NCT04512456 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05997420 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study NCT05339841 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05031052 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06470685 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT05848102 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06426511 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06585761 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06383507 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT05602961 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06290453 — Predictive Biomarker (PRD): FSTL1 mRNA
Genes: FSTL1; FRP
Study NCT04664179 — Predictive Biomarker (PRD): IL7 mRNA
Genes: IL7
Study NCT04990037 — Predictive Biomarker (PRD): IL1RAP mRNA
Genes: IL1RAP; C3orf13; IL1R3
Study NCT06173024 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT05313477 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05459974 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06162611 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study NCT05776329 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT05034042 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06231095 — Safety Biomarker (SAF): BDNF
Study NCT06441214 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study NCT04904419 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study NCT06068803 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT05721898 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05196256 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04692441 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT04937920 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study NCT05074680 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7