TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05703685 — Predictive Biomarker (PRD): PDE4B mRNA
Genes: PDE4B; DPDE4
Study NCT06446128 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06446128 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT06446128 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04246762 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT04246762 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT04246762 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04246762 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04246762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06078826 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06109831 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06091904 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06314009 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT06182917 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT06182917 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06518915 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05536297 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT05695976 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05695976 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04855370 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT05741827 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06400446 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06462313 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05218408 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT05218408 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04925492 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05808439 — Predictive Biomarker (PRD): AAAS mRNA
Genes: AAAS; ADRACALA; GL003
Study NCT06291714 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06193707 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05340413 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT05340413 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT05340413 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT05340413 — Predictive Biomarker (PRD): RAD51C mRNA
Genes: RAD51C; RAD51L2
Study NCT05340413 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study NCT05247034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05247034 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05247034 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05247034 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05247034 — Surrogate Endpoint (SUR): Serum hemoglobin A1C
Study NCT05247034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05247034 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT05247034 — Safety Biomarker (SAF): Interleukin 1
Study NCT05247034 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study NCT05247034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05024552 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05709847 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT06248151 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06717022 — Predictive Biomarker (PRD): MSLN mRNA
Genes: MSLN; MPF
Study NCT05377060 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04551495 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT04551495 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study NCT04996667 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04972253 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT04972253 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT04972253 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT05679713 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study NCT04971928 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT05810519 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT05878574 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05940350 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05197699 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06631040 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03137966 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT04562116 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT04562116 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT04562116 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04562116 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT04562116 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT06645795 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05793983 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study NCT05899179 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT05895994 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT05232630 — Predictive Biomarker (PRD): SYNGAP1 mRNA
Genes: SYNGAP1; KIAA1938
Study NCT05232630 — Predictive Biomarker (PRD): STXBP1 mRNA
Genes: STXBP1; UNC18A
Study NCT05566587 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT05432310 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT05263960 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05079269 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04465734 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05420948 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06252376 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06184997 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05261711 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05661162 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06659926 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05114746 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04678401 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05400174 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06289036 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT06274983 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT05522738 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06326021 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT05216705 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study NCT05216705 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT05216705 — Predictive Biomarker (PRD): UCHL1 mRNA
Genes: UCHL1
Study NCT06718530 — Predictive Biomarker (PRD): HLA-E mRNA
Genes: HLA-E; HLA-6.2; HLAE
Study NCT04748185 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06719154 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06715137 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study NCT06715137 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06715137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04680260 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05981534 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT06659588 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT06659588 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study NCT05615402 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05778656 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT05778656 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study NCT05778656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05778656 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05980598 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study NCT06633757 — Predictive Biomarker (PRD): DNAI1 mRNA
Genes: DNAI1
Study NCT06661252 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT05888155 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT05130840 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05130840 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06551220 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04477616 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06477783 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05577611 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study NCT06279611 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04803006 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study NCT05496816 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT05496816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05496816 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT05227170 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT05227170 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study NCT05227170 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06033287 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06033287 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06033287 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT06033287 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT06659042 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04998851 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04866069 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05030467 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05275673 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study NCT05631249 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04875520 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05359250 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05359250 — Predictive Biomarker (PRD): TDO2 mRNA
Genes: TDO2; TDO
Study NCT05419856 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study NCT04650581 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study NCT04650581 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05918445 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05748821 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06050980 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06301841 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT06541808 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02824094 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT05817409 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT06278051 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05383911 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT04430426 — Predictive Biomarker (PRD): AGXT mRNA
Genes: AGXT; AGT1; SPAT
Study NCT04430426 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT05504707 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05504707 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT05504707 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04979598 — Predictive Biomarker (PRD): MEOX1 mRNA
Genes: MEOX1; MOX1
Study NCT06600425 — Predictive Biomarker (PRD): DNAI1 mRNA
Genes: DNAI1
Study NCT05961371 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06677411 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study NCT06680921 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06680921 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05570994 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05601466 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT06718920 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT06718855 — Predictive Biomarker (PRD): SGCA mRNA
Genes: SGCA; ADL; DAG2
Study NCT06304636 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06716788 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT06125106 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06718985 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06716047 — Predictive Biomarker (PRD): NOD2 mRNA
Genes: NOD2; CARD15; IBD1
Study NCT06712810 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study NCT06717594 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT06719414 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05812339 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT06062017 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06225882 — Predictive Biomarker (PRD): AGXT mRNA
Genes: AGXT; AGT1; SPAT
Study NCT05906771 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05912621 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT06064487 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2
Study NCT06064487 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT06237751 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT05958914 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study NCT05636202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05636202 — Safety Biomarker (SAF): Platelet to lymphocyte
Study NCT04843631 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT05160415 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study NCT05980130 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04703140 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04935749 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study NCT04589130 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05705700 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT05132348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04807725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04807725 — Safety Biomarker (SAF): Interleukin 1
Study NCT05095246 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03939585 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05800977 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05625399 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study NCT06053242 — Predictive Biomarker (PRD): DDT mRNA
Genes: DDT
Study NCT05486390 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05576181 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05495581 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06100705 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05993741 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT05947838 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05958589 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04244604 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06341400 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT06447675 — Predictive Biomarker (PRD): Cyclin-dependent kinase-like 5
Genes: CDKL5; STK9
Study NCT06562842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06562842 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06562842 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05382338 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT03180450 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05570188 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05807126 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study NCT05807126 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06716164 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06715826 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06719518 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06717815 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06716138 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT06068504 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05857319 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05034393 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05034393 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05780879 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06226636 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05315180 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study NCT05539248 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT05729724 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06127238 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT06127238 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT06127238 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT06127238 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study NCT06127238 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT06127238 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT05001945 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05746247 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT04416113 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06206850 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06206850 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04661033 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT05884372 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05884372 — Surrogate Endpoint (SUR): Serum calcium
Study NCT05286710 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study NCT04661150 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05298475 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT05298475 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05298475 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05817461 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04812938 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT06085755 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06085755 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00168467 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05572801 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06068374 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05938387 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT06539754 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05343988 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06411990 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05922930 — Predictive Biomarker (PRD): TACSTD2 mRNA
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study NCT05922930 — Predictive Biomarker (PRD): IL15 mRNA
Genes: IL15
Study NCT05772325 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05054764 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04723706 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06717958 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT06715215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06715215 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT06124157 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT05833217 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05117814 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT06211699 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05013554 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05801913 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05383313 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF