TrialPanorama/TrialPanorama-database huggingface dataset:
Study 34199645 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34199645 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34199645 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 36255262 — Safety Biomarker (SAF): Hyaluronic acid
Study 32179149 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 32179149 — Surrogate Endpoint (SUR): Serum creatinine
Study 35609978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35609978 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 35609978 — Safety Biomarker (SAF): C-C motif chemokine 19
Genes: CCL19; ELC; MIP3B; SCYA19
Study 35609978 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 32948120 — Surrogate Endpoint (SUR): Blood pressure
Study 32948120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36182594 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32645934 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 35931975 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 32615321 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32141817 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 32182747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36121656 — Surrogate Endpoint (SUR): Blood pressure
Study 32655006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32655006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35045722 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 35045722 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35045722 — Surrogate Endpoint (SUR): Blood pressure
Study 36103557 — Predictive Biomarker (PRD): KLK2 mRNA
Genes: KLK2
Study 36103557 — Predictive Biomarker (PRD): KLK3 mRNA
Genes: KLK3; APS
Study 32808179 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 33829236 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 33095139 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 36342163 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 36342163 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33529342 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 33529342 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33529342 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34518033 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33125266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35902898 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32660432 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 32073511 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 32073511 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study 32889091 — Surrogate Endpoint (SUR): Pathological complete response
Study 33458928 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 33458928 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 33458928 — Predictive Biomarker (PRD): LEPROT mRNA
Genes: LEPROT; LEPR; OBR
Study 35296307 — Surrogate Endpoint (SUR): Blood pressure
Study 32204978 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 32204978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34089422 — Surrogate Endpoint (SUR): Bone mineral density
Study 36125103 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 36123011 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 616388350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32376818 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 32376818 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34721416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35263421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32779269 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32723555 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 32184313 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 35025993 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study 35025993 — Surrogate Endpoint (SUR): Serum triglycerides
Study 35025993 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35025993 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35594693 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 35594693 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 35594693 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 32865004 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32805324 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 32539079 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33660875 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34076308 — Surrogate Endpoint (SUR): Serum calcium
Study 35021257 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 33751644 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33498220 — Surrogate Endpoint (SUR): Blood pressure
Study 34962245 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 34962245 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33734043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33734043 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32958699 — Predictive Biomarker (PRD): MGST1 mRNA
Genes: MGST1; GST12; MGST
Study 32958699 — Predictive Biomarker (PRD): LMO3 mRNA
Genes: LMO3; RBTN3; RBTNL2; RHOM3
Study 32958699 — Predictive Biomarker (PRD): AXIN1 mRNA
Genes: AXIN1; AXIN
Study 36183982 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 36183982 — Predictive Biomarker (PRD): PRX mRNA
Genes: PRX; KIAA1620
Study 36183982 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32904579 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32904579 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32904579 — Surrogate Endpoint (SUR): Blood pressure
Study 34553463 — Surrogate Endpoint (SUR): Serum testosterone
Study 32051393 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 32051393 — Predictive Biomarker (PRD): CCL24 mRNA
Genes: CCL24; MPIF2; SCYA24
Study 32051393 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 32609534 — Surrogate Endpoint (SUR): Serum sodium
Study 36014824 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36014824 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33638976 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32221582 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32221582 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32069356 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 33522946 — Surrogate Endpoint (SUR): Serum calcium
Study 616836595 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 616836595 — Surrogate Endpoint (SUR): Blood pressure
Study 35165382 — Predictive Biomarker (PRD): TXNIP mRNA
Genes: TXNIP; VDUP1
Study 35799756 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32817131 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 36387350 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 32782077 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32782077 — Surrogate Endpoint (SUR): Blood pressure
Study 35175971 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 34222086 — Predictive Biomarker (PRD): SERPINF1 mRNA
Genes: SERPINF1; PEDF; PIG35
Study 32563277 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32563277 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 34963006 — Predictive Biomarker (PRD): DPEP1 mRNA
Genes: DPEP1; MDP; RDP
Study 33022345 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33022345 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 33022345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33022345 — Safety Biomarker (SAF): BDNF
Study 33022345 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 35249225 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 32245464 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 35898773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33904664 — Surrogate Endpoint (SUR): Blood pressure
Study 34951021 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 34951021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34951021 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34906334 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 34906334 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 32385016 — Surrogate Endpoint (SUR): Blood pressure
Study 33356011 — Surrogate Endpoint (SUR): Blood pressure
Study 34119421 — Surrogate Endpoint (SUR): Blood pressure
Study 34906295 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 34906295 — Safety Biomarker (SAF): Vascular endothelial cadherin
Genes: CDH5
Study 34565678 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 36382849 — Predictive Biomarker (PRD): NEDD8 mRNA
Genes: NEDD8
Study 32975708 — Predictive Biomarker (PRD): UNC13D mRNA
Genes: UNC13D
Study 32975708 — Predictive Biomarker (PRD): Hormone receptor
Study 32613209 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 35131096 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 35131096 — Surrogate Endpoint (SUR): Blood pressure
Study 32782219 — Predictive Biomarker (PRD): Protein patched homolog 1
Genes: PTCH1; PTCH
Study 32820083 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study 33074074 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 36208293 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 32858361 — Surrogate Endpoint (SUR): Blood pressure
Study 32831874 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): miR-124
Study 35984904 — Predictive Biomarker (PRD): SOCS1 mRNA
Genes: SOCS1; SSI1; TIP3
Study 32000419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32000419 — Surrogate Endpoint (SUR): Blood pressure
Study 34161051 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 33045833 — Predictive Biomarker (PRD): IFIT1 mRNA
Genes: IFIT1; G10P1; IFI56; IFNAI1; ISG56
Study 33045833 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 35342439 — Surrogate Endpoint (SUR): Blood pressure
Study 36320825 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32669306 — Surrogate Endpoint (SUR): Blood pressure
Study 34382717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36279795 — Predictive Biomarker (PRD): NPC1 mRNA
Genes: NPC1
Study 33974688 — Surrogate Endpoint (SUR): Bone mineral density
Study 32140704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32140704 — Surrogate Endpoint (SUR): Blood pressure
Study 33065547 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 33065547 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33065547 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 36355053 — Surrogate Endpoint (SUR): Bone mineral density
Study 34702946 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 34702946 — Predictive Biomarker (PRD): VNN2 mRNA
Genes: VNN2
Study 34702946 — Predictive Biomarker (PRD): CSF3R mRNA
Genes: CSF3R; GCSFR
Study 34702946 — Predictive Biomarker (PRD): PTPRE mRNA
Genes: PTPRE
Study 34702946 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study 34702946 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 32879152 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 33715382 — Predictive Biomarker (PRD): F2R mRNA
Genes: F2R; CF2R; PAR1; TR
Study 35553560 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 33493450 — Safety Biomarker (SAF): Interleukin 1
Study 33493450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32358638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32358638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32358638 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32358638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34251534 — Surrogate Endpoint (SUR): Probing pocket depth
Study 34251534 — Safety Biomarker (SAF): Interleukin 1
Study 34251534 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 32546992 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 36465612 — Predictive Biomarker (PRD): MAP3K5 mRNA
Genes: MAP3K5; ASK1; MAPKKK5; MEKK5
Study 32168417 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 32168417 — Predictive Biomarker (PRD): PCSK7 mRNA
Genes: PCSK7; LPC; PC7; PC8; SPC7
Study 35150943 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 34011674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33970899 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 34612846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34612846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34612846 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34612846 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33359595 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 33359595 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 33359595 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 33359595 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34192714 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 34076665 — Surrogate Endpoint (SUR): Blood pressure
Study 34076665 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37216189 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 34384882 — Predictive Biomarker (PRD): Hormone receptor
Study 34375362 — Surrogate Endpoint (SUR): Blood pressure
Study 32353592 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 32353592 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 32353592 — Predictive Biomarker (PRD): BLOC1S2 mRNA
Genes: BLOC1S2; BLOS2; CEAP
Study 34378869 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35816140 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32693740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35048309 — Surrogate Endpoint (SUR): Blood pressure
Study 34523063 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 36282205 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 36282205 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 36282205 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 32289159 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33491436 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33295974 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 35686579 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 34083384 — Predictive Biomarker (PRD): GPR84 mRNA
Genes: GPR84; EX33
Study 34083384 — Predictive Biomarker (PRD): FFAR4 mRNA
Genes: FFAR4; GPR120; GPR129; O3FAR1; PGR4
Study 34083384 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 33405082 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33939887 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 35605174 — Predictive Biomarker (PRD): Hormone receptor
Study 35605174 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33044849 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Growth/differentiation factor 8
Genes: MSTN; GDF8
Study 33044849 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 34413391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32553818 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 35881122 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32272516 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 32157099 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32157099 — Safety Biomarker (SAF): BDNF
Study 33661958 — Surrogate Endpoint (SUR): Blood pressure
Study 36268690 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32725589 — Predictive Biomarker (PRD): RHOF mRNA
Genes: RHOF; ARHF; RIF
Study 32725589 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 35838997 — Surrogate Endpoint (SUR): Blood pressure
Study 33074282 — Surrogate Endpoint (SUR): Blood pressure
Study 34301748 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33198760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33198760 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 33198760 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32096346 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 32199333 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32199333 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35096107 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 33549554 — Surrogate Endpoint (SUR): Blood pressure
Study 34715162 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34715162 — Safety Biomarker (SAF): BDNF
Study 32194222 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 32194222 — Predictive Biomarker (PRD): SESN2 mRNA
Genes: SESN2; Hi95; SEST2
Study 33891333 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 33891333 — Surrogate Endpoint (SUR): Blood pressure
Study 34748565 — Surrogate Endpoint (SUR): Bone mineral density
Study 35717050 — Predictive Biomarker (PRD): SERPINB3 mRNA
Genes: SERPINB3; SCCA; SCCA1
Study 33888981 — Surrogate Endpoint (SUR): Blood pressure
Study 34104089 — Predictive Biomarker (PRD): LRP1 mRNA
Genes: LRP1; A2MR; APR
Study 34104089 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study 34913020 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34228505 — Surrogate Endpoint (SUR): Serum asparaginase
Study 32302702 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32362231 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 32362231 — Surrogate Endpoint (SUR): Blood pressure
Study 32401418 — Surrogate Endpoint (SUR): Blood pressure
Study 36262374 — Predictive Biomarker (PRD): TNNT1 mRNA
Genes: TNNT1; TNT
Study 34488858 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35639865 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 32481440 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32481440 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34953184 — Safety Biomarker (SAF): Hyaluronic acid