TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT06184360 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT06184360 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06184360 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04519983 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06161753 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT05308225 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT06064786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04953884 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT04838626 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05443126 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT05458063 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study NCT05706337 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05196243 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT04759248 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04759248 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04759248 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04759248 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study NCT05405725 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05050474 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05233163 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06625515 — Predictive Biomarker (PRD): DHX9 mRNA
Genes: DHX9; DDX9; LKP; NDH2
Study NCT06774079 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT05165602 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06303869 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study NCT05629442 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06209606 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04781231 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05287451 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT05851911 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05918328 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05918328 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT06358469 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT06630325 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study NCT06630325 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT06773819 — Predictive Biomarker (PRD): IVL mRNA
Genes: IVL
Study NCT06577935 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06770179 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04943497 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04943497 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04943497 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT06136546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05082025 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT05082025 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT05082025 — Predictive Biomarker (PRD): PIK3R1 mRNA
Genes: PIK3R1; GRB1
Study NCT05082025 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT05082025 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06582524 — Safety Biomarker (SAF): Arginase-1
Genes: ARG1
Study NCT05677490 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05704400 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT05704400 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT05704400 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT04978649 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05162443 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04821141 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT05580458 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05682547 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05943522 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT05943522 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT06080737 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06018805 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04906590 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05983796 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05130827 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06735859 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06738303 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06737549 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT06738368 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06740708 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05722730 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06738758 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT05862493 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06184750 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06739005 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study NCT06740760 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT05947604 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00662077 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06740786 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05694715 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05694715 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT05694715 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT05521048 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT04564482 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04987112 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study NCT06074588 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06074588 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06074588 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT06074588 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT06074588 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT06074588 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04228549 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05647902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04882332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT05479994 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT05100316 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT05028764 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study NCT06203249 — Predictive Biomarker (PRD): IFIH1 mRNA
Genes: IFIH1; MDA5; RH116
Study NCT06051097 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05488951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05488951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00210665 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT06508164 — Predictive Biomarker (PRD): RYR2 mRNA
Genes: RYR2
Study NCT05332574 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06287463 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study NCT04739033 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05520567 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05444673 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02792725 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02792725 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05368506 — Predictive Biomarker (PRD): WEE1 mRNA
Genes: WEE1
Study NCT05368506 — Predictive Biomarker (PRD): CHEK1 mRNA
Genes: CHEK1; CHK1
Study NCT05948462 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06576037 — Predictive Biomarker (PRD): TRPV6 mRNA
Genes: TRPV6; ECAC2
Study NCT05203445 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05203445 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05203445 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04609683 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05294731 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04281498 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT05464446 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT05887804 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05376683 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04813263 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04842682 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT06083337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06178809 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT06734351 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06602193 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT06774235 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT06771154 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT06774027 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06774027 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06774027 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06773299 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04862260 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study NCT04862260 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06771245 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05855746 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT06773572 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study NCT06773572 — Predictive Biomarker (PRD): CD81 mRNA
Genes: CD81; TAPA1; TSPAN28
Study NCT06773572 — Predictive Biomarker (PRD): SIRT3 mRNA
Genes: SIRT3; SIR2L3
Study NCT06773572 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06326463 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT06688786 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06688786 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT06724432 — Safety Biomarker (SAF): miR-124a
Study NCT06772454 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06735924 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT06738797 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06738797 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06770907 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study NCT06128980 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study NCT06128980 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study NCT06128980 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT06532474 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT06358274 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06770452 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06772376 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05976230 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06122428 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03714477 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00092924 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study NCT06736717 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06736717 — Predictive Biomarker (PRD): PLK1 mRNA
Genes: PLK1; PLK
Study NCT06023225 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT06737965 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT05885997 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05445011 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT06740461 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05491057 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05090124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05668858 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06168851 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT06168851 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT05290597 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06115499 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06115499 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT06115499 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT00001057 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05841433 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT06270693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05022342 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT05022342 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04757155 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study NCT04348682 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05406700 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT05406700 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT06504589 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT06307938 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06270290 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study NCT05926024 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT05803889 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04737200 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04666129 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT04864548 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06459180 — Predictive Biomarker (PRD): TACSTD2 mRNA
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study NCT05130450 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05037097 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05037097 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05673304 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT04891991 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04891991 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT06328166 — Safety Biomarker (SAF): Fibroblast growth factor 1
Genes: FGF1
Study NCT05969938 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05948891 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06576921 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT04638946 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06302439 — Predictive Biomarker (PRD): ENPP1 mRNA
Genes: ENPP1; M6S1; NPPS; PC1; PDNP1
Study NCT06302439 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study NCT06469944 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06469944 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05946226 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT06238024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06364319 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT04838847 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04838847 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05630989 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06491914 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06491914 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05211297 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05472220 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT06413680 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT06413680 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05975866 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT05975866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04863586 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT05436509 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05877196 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05597306 — Predictive Biomarker (PRD): KDM1A mRNA
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study NCT05748288 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT05039229 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05620914 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT05655195 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06593600 — Predictive Biomarker (PRD): NPR1 mRNA
Genes: NPR1; ANPRA
Study NCT06593600 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06660654 — Predictive Biomarker (PRD): CDH6 mRNA
Genes: CDH6
Study NCT04907214 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06598800 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06598800 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05157204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05157204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05209074 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT06561555 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05622201 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04742192 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06386146 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT05449249 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT06705140 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06743191 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06739434 — Predictive Biomarker (PRD): MECP2 mRNA
Genes: MECP2
Study NCT06741007 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT05222165 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT05222165 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT05222165 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT06739486 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06736951 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study NCT06764940 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06410651 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04751760 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT05252741 — Predictive Biomarker (PRD): SERPINF1 mRNA
Genes: SERPINF1; PEDF; PIG35
Study NCT06775041 — Predictive Biomarker (PRD): ZMPSTE24
Genes: FACE-1; Ste24p; STE24; HGPS; PRO1
Study NCT06771141 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04689750 — Predictive Biomarker (PRD): STUB1 mRNA
Genes: STUB1; CHIP; PP1131
Study NCT05115279 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT04857372 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT04857372 — Predictive Biomarker (PRD): LATS1 mRNA
Genes: LATS1; WARTS
Study NCT04857372 — Predictive Biomarker (PRD): LATS2 mRNA
Genes: LATS2; KPM
Study NCT04857372 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study NCT06435273 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT04963153 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM