TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05475262 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03825484 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT05220917 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT06680986 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06235320 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05760105 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05184387 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study NCT05843045 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT05843045 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT04729751 — Predictive Biomarker (PRD): ATP8B1 mRNA
Genes: ATP8B1; ATPIC; FIC1; PFIC
Study NCT05122455 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT05122455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06565208 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04334759 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05377203 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05647083 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05331105 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT04760990 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06134908 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05692193 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05415215 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05415215 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05464173 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05464173 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05924100 — Predictive Biomarker (PRD): GDF11 mRNA
Genes: GDF11; BMP11
Study NCT05924100 — Predictive Biomarker (PRD): Chromosome 5q
Study NCT04845893 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT06269211 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06340568 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05584332 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05612269 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05612269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05208853 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT06455787 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT01089452 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01089452 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00002174 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT06348472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05800873 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05738629 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04653675 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT05894512 — Predictive Biomarker (PRD): THSD7A mRNA
Genes: THSD7A; KIAA0960
Study NCT06383559 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT05861895 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06684769 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT06688331 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05030818 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01855087 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT06692465 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT05110365 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05137990 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06517745 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06118463 — Predictive Biomarker (PRD): AUNIP mRNA
Genes: AUNIP; C1orf135
Study NCT06311851 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06311851 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05741658 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05209178 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03529448 — Predictive Biomarker (PRD): TRIB3
Genes: dJ1103G7.3; TRB3
Study NCT06680778 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06681402 — Predictive Biomarker (PRD): TLR5
Genes: TIL3; FLJ10052; MGC126430; MGC126431
Study NCT06680180 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT05218668 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT04581408 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04935138 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04843371 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04753736 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05964153 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05909683 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT05463003 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT05303519 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT05110898 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04547140 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT04978597 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT02919137 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05267288 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05267288 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05684562 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06111521 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT06111521 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04758078 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study NCT05136131 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05991219 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study NCT05221307 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04433533 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04433533 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06488313 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study NCT05915728 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04659239 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05139082 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06557486 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04844177 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04844177 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06286280 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT06314490 — Predictive Biomarker (PRD): SCN2A mRNA
Genes: SCN2A; NAC2; SCN2A1; SCN2A2
Study NCT04714190 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04714190 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04885114 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT06019949 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04728698 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04962048 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study NCT05693766 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05693766 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04556084 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05318937 — Predictive Biomarker (PRD): SAGE1 mRNA
Genes: SAGE1; SAGE
Study NCT04922996 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05777343 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT06338150 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT05058352 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT04940208 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT06191523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06191523 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT06191523 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT05116007 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05304208 — Predictive Biomarker (PRD): DCT mRNA
Genes: DCT; TYRP2
Study NCT05307289 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05307289 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT06681337 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06681337 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05168605 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04711252 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04711252 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04711252 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04711252 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05691036 — Predictive Biomarker (PRD): ABCB4 mRNA
Genes: ABCB4; MDR3; PGY3
Study NCT05691036 — Predictive Biomarker (PRD): ATP8B1 mRNA
Genes: ATP8B1; ATPIC; FIC1; PFIC
Study NCT06305104 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT05318339 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05007782 — Predictive Biomarker (PRD): CCR8 mRNA
Genes: CCR8; CKRL1; CMKBR8; CMKBRL2
Study NCT06149403 — Predictive Biomarker (PRD): IDUA mRNA
Genes: IDUA
Study NCT05464030 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT05516277 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05702684 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study NCT05941377 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06558019 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT04849104 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT04909515 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05251636 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05896761 — Predictive Biomarker (PRD): A2M mRNA
Genes: A2M; CPAMD5; FWP007
Study NCT05635071 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT05635071 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT04906460 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT05476354 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06625190 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06556472 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT06449417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06449417 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06053099 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06424847 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05327205 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05890742 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT05592951 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT05592951 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05292404 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT06557824 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00000663 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06557317 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05070156 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT06428708 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05346354 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT06015230 — Predictive Biomarker (PRD): IFNAR1 mRNA
Genes: IFNAR1; IFNAR
Study NCT06057077 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT04910971 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05329909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT06209788 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05283239 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05743608 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05103631 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT05103631 — Predictive Biomarker (PRD): IL15 mRNA
Genes: IL15
Study NCT05338359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05338359 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT05636826 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06122116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05181462 — Predictive Biomarker (PRD): IL1RAP mRNA
Genes: IL1RAP; C3orf13; IL1R3
Study NCT05181462 — Safety Biomarker (SAF): Interleukin 1
Study NCT05966792 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05966792 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT04965766 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT04965766 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04965766 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04965766 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05016349 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study NCT05016349 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT05016349 — Predictive Biomarker (PRD): CYP26A1 mRNA
Genes: CYP26A1; CYP26; P450RAI1
Study NCT05016349 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06665672 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06672146 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT06680570 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06680128 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06680011 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study NCT06680895 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT04932525 — Predictive Biomarker (PRD): STING1 mRNA
Genes: STING1; ERIS; MITA; STING; TMEM173
Study NCT05655936 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05434403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04794517 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05630105 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT06558084 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05703802 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT06111144 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study NCT00093548 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT00093548 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05645783 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04844697 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04617171 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT05373134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05373134 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT06221670 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06221670 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05490953 — Safety Biomarker (SAF): Cytochrome c
Study NCT05235477 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06373081 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06373081 — Predictive Biomarker (PRD): T-cell surface glycoprotein CD3 epsilon
Genes: CD3E; T3E
Study NCT05819606 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05819606 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT06383767 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06383767 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05554575 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT06569082 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00002008 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05709158 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06309719 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00006291 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00006291 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00006291 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study NCT06318234 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT06298435 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05750160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05750160 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT05750160 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT06261060 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study NCT05047913 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT05187013 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06670365 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05024773 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06680635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06680635 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT06680635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06680635 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study NCT06680635 — Safety Biomarker (SAF): Interleukin 1
Study NCT06680635 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT06681038 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06681038 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT06681285 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT06680388 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05181033 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05181033 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT05181033 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05181033 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05333328 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04354961 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06467942 — Predictive Biomarker (PRD): PAX1 mRNA
Genes: PAX1; HUP48
Study NCT05183763 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06402630 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT05126043 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05126043 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05318534 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study NCT06079476 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06359379 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT05753384 — Predictive Biomarker (PRD): ITK mRNA
Genes: ITK; EMT; LYK
Study NCT05753384 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT05753384 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT05239286 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05349721 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT05737849 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05737849 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05491681 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT06258629 — Predictive Biomarker (PRD): CD200 mRNA
Genes: CD200; MOX1; MOX2; My033
Study NCT05304715 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT04956549 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT05044091 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT04710043 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study NCT05943847 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05943847 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT05943847 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study NCT05943847 — Safety Biomarker (SAF): BDNF
Study NCT06556784 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06556784 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein