TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT06507969 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05971589 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT05971589 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05847244 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05259878 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05949671 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT04591184 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06026020 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT06019910 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05953974 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT05213780 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05516303 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT05969379 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05167604 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06243445 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05587114 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05875220 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05238818 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT05171582 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04371952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05913141 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT00496535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05066477 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06429241 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study NCT06477484 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT06495515 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06495515 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00001993 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05672719 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05247840 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06217861 — Predictive Biomarker (PRD): GCDH mRNA
Genes: GCDH
Study NCT04714320 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study NCT04847349 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04847349 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04913922 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04913922 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study NCT06157476 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05414188 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05483725 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05301153 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05441189 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT05433363 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04604223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04604223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04585984 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT05854823 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT06348706 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04241666 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT06633211 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00299845 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT06148142 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05333991 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT05061186 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06283576 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT05549635 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT05827835 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT05506410 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04060316 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT06399809 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04811365 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT05786014 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06412718 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06412718 — Predictive Biomarker (PRD): PAX6 mRNA
Genes: PAX6; AN2
Study NCT06151496 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06460142 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study NCT05199129 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05646420 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study NCT06295848 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05916261 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05993130 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05277623 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05157867 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT05157867 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT05899751 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04993014 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06483347 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT06483347 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06483347 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05172193 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06060808 — Predictive Biomarker (PRD): NFKBIA mRNA
Genes: NFKBIA; IKBA; MAD3; NFKBI
Study NCT06060808 — Predictive Biomarker (PRD): PTPN22 mRNA
Genes: PTPN22; PTPN8
Study NCT06405217 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT05284175 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT05284175 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT06088056 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03180463 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04973930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00001049 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05624775 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05624775 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05803928 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT05803928 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT05803928 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT05803928 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT06243822 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05429229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05429229 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT05429229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05429229 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT04146571 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06206278 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT05019677 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study NCT05019677 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study NCT06518200 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04709796 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05110664 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT05702671 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT06127563 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06379802 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05257967 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05257967 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04825652 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06253819 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06552806 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05132036 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05947747 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study NCT06402370 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04813939 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study NCT05950230 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study NCT04787588 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study NCT06036095 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT05845918 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04877314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04877314 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT06013839 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06483568 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05192694 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06372821 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05876663 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05963048 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05199519 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT06530810 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT05933980 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT05445674 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT05763108 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study NCT05763108 — Predictive Biomarker (PRD): COL5A1 mRNA
Genes: COL5A1
Study NCT05669638 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06054711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05621408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05374278 — Predictive Biomarker (PRD): SLC1A2 mRNA
Genes: SLC1A2; EAAT2; GLT1
Study NCT05657704 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT05704517 — Predictive Biomarker (PRD): ATP8B1 mRNA
Genes: ATP8B1; ATPIC; FIC1; PFIC
Study NCT05760586 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT05189782 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05505552 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study NCT05994001 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05353166 — Predictive Biomarker (PRD): NPR1 mRNA
Genes: NPR1; ANPRA
Study NCT05353166 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT06417736 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study NCT06417736 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT05385406 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT04915482 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT04915482 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04556266 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05727371 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04660383 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT05026034 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study NCT04471974 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT06009627 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06009627 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04979949 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05263622 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT06084897 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT05386654 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04848454 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04848454 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05160558 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study NCT06626685 — Predictive Biomarker (PRD): STUB1 mRNA
Genes: STUB1; CHIP; PP1131
Study NCT06711354 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06024889 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05200897 — Safety Biomarker (SAF): BDNF
Study NCT06396065 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05561543 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06633328 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT06633354 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study NCT05101486 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05843019 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT05721118 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05230836 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT05325307 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06115655 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05145179 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05836519 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04940507 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04917289 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04709770 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04360096 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study NCT03994497 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT04865809 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT05426369 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study NCT05426369 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT05241028 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06237179 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT06178432 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT05266768 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04800627 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04914078 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT05921357 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT04859179 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT00304837 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00304837 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06583473 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05949606 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study NCT05949606 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05157373 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT05771844 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study NCT05308914 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06037980 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study NCT04729062 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT04972487 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT05379049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05379049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00000875 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00000875 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05520749 — Predictive Biomarker (PRD): GDF11 mRNA
Genes: GDF11; BMP11
Study NCT05520749 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Growth/differentiation factor 8
Genes: MSTN; GDF8
Study NCT05225051 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT05161390 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT05776667 — Predictive Biomarker (PRD): SFRP2 mRNA
Genes: SFRP2; FRP2; SARP1; FKSG12; UNQ361/PRO697
Study NCT06165250 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06396767 — Predictive Biomarker (PRD): DIAPH2 mRNA
Genes: DIAPH2; DIA
Study NCT06345105 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT04467801 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study NCT03786237 — Predictive Biomarker (PRD): COL7A1 mRNA
Genes: COL7A1
Study NCT06309654 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06422546 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05517330 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04849065 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT04700852 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study NCT04700852 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT04700852 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT06058819 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06058819 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT06058819 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06058819 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT06058819 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT06058819 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study NCT06361979 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04934410 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06158256 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06632561 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT05905341 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05905341 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05905341 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05982717 — Predictive Biomarker (PRD): SCN1A mRNA
Genes: SCN1A; NAC1; SCN1
Study NCT06213935 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04521582 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05067192 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT04826692 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT05713851 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study NCT05713851 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT06429579 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT06293664 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT06293664 — Predictive Biomarker (PRD): MC5R mRNA
Genes: MC5R
Study NCT06165601 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06249256 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06249256 — Predictive Biomarker (PRD): MSLN mRNA
Genes: MSLN; MPF
Study NCT05280132 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT05106907 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05671705 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study NCT06630416 — Predictive Biomarker (PRD): KMT2D mRNA
Genes: KMT2D; ALR; MLL2; MLL4
Study NCT06630416 — Predictive Biomarker (PRD): MTAP mRNA
Genes: MTAP; MSAP
Study NCT05228106 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06166914 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT05929924 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT04903184 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05955196 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study NCT05582265 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06087042 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT05856630 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT05498675 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05346536 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT06158945 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT05326230 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05092087 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05092087 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol