TrialPanorama/TrialPanorama-database huggingface dataset:
Study 38382153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 38382153 — Predictive Biomarker (PRD): IL7 mRNA
Genes: IL7
Study 38382153 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 38382153 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 38382153 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 38382153 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38382311 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 38382419 — Predictive Biomarker (PRD): miR-19a
Genes: MIR19A
Study 38382813 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38382813 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 38383345 — Surrogate Endpoint (SUR): Blood pressure
Study 38383458 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 38383458 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38383461 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 38383476 — Surrogate Endpoint (SUR): Blood pressure
Study 38383578 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 38384123 — Safety Biomarker (SAF): IL-6 and IL-10
Study 38384458 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 38384458 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 38384879 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 38385566 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 38385926 — Predictive Biomarker (PRD): IVL mRNA
Genes: IVL
Study 38385926 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 38386266 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 38386949 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 38386978 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 38388167 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38388171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38388489 — Surrogate Endpoint (SUR): Forced vital capacity
Study 38388489 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 38388646 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 38388646 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 38388646 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 38390395 — Surrogate Endpoint (SUR): Blood pressure
Study 38390795 — Surrogate Endpoint (SUR): Blood pressure
Study 38390800 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 38390815 — Surrogate Endpoint (SUR): Blood pressure
Study 38391202 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38391282 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 38393723 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study 38394720 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 38395023 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 38395023 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 38395537 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 38396455 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38396455 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 38400158 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 38400919 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 38400984 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38401202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 38401646 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38401646 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 38401647 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 38402353 — Surrogate Endpoint (SUR): Blood pressure
Study 38402374 — Predictive Biomarker (PRD): GPRC5D mRNA
Genes: GPRC5D
Study 38402467 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 38403793 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 38403984 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 38404989 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38406514 — Predictive Biomarker (PRD): BMF mRNA
Genes: BMF
Study 38406813 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38406813 — Surrogate Endpoint (SUR): Pathological complete response
Study 38407317 — Predictive Biomarker (PRD): ATRX mRNA
Genes: ATRX; RAD54L; XH2
Study 38407317 — Predictive Biomarker (PRD): DAXX mRNA
Genes: DAXX; BING2; DAP6
Study 38407317 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 38407508 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38407630 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 38407817 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38407859 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 38408067 — Surrogate Endpoint (SUR): Blood pressure
Study 38408725 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 38408999 — Predictive Biomarker (PRD): RORA
Genes: RZRA; ROR1; ROR2; ROR3; NR1F1; ROR-alpha; RORalpha; RORa1
Study 38408999 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 38409229 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 38409229 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study 38409229 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 38409229 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 38409332 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 38410109 — Predictive Biomarker (PRD): CD276 mRNA
Genes: CD276; B7H3; PSEC0249; UNQ309/PRO352
Study 38410116 — Predictive Biomarker (PRD): SQSTM1 mRNA
Genes: SQSTM1; ORCA; OSIL
Study 38410116 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 38410608 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38410766 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 38411246 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 38411246 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38412310 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 38412310 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 38412408 — Predictive Biomarker (PRD): PTCHD3 mRNA
Genes: PTCHD3; PTR
Study 38412543 — Surrogate Endpoint (SUR): Blood pressure
Study 38413153 — Predictive Biomarker (PRD): ZDHHC2 mRNA
Genes: ZDHHC2; REAM; REC; ZNF372
Study 38413153 — Predictive Biomarker (PRD): NISCH mRNA
Genes: NISCH; IRAS; KIAA0975
Study 38413153 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 38413161 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 38413410 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FasL mRNA
Genes: FASLG; APT1LG1; CD95L; FASL; TNFSF6
Study 38413410 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 38413410 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 38413410 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 38413410 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38413796 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 38413796 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 38413796 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38413796 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 38413796 — Monitoring Biomarker (MOI): Cell-free DNA
Study 38413930 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 38413930 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 38413930 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38413930 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 38414045 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 38414067 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 38414067 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study 38414067 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 38414067 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 38414510 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 38414510 — Monitoring Biomarker (MOI): Cell-free DNA
Study 38414658 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 38415370 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 38415785 — Predictive Biomarker (PRD): TLR8 mRNA
Genes: TLR8; UNQ249/PRO286
Study 38416176 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 38416176 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 38416237 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 38417277 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 38417277 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 38418002 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 38418004 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 38418234 — Surrogate Endpoint (SUR): Pathological complete response
Study 38418236 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 38418350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38418563 — Surrogate Endpoint (SUR): Forced vital capacity
Study 38418879 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study 38419035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38419131 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 38419600 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 38420260 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38420657 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 38420809 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 38421092 — Surrogate Endpoint (SUR): Blood pressure
Study 38421647 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 38421679 — Safety Biomarker (SAF): Hyaluronic acid
Study 38421881 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 38421881 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 38421881 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 38422450 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38422473 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 38422781 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 38422781 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 38422953 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 38422953 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 38423010 — Predictive Biomarker (PRD): SNF8 mRNA
Genes: SNF8; EAP30
Study 38423030 — Predictive Biomarker (PRD): GRPR mRNA
Genes: GRPR
Study 38423582 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 38423752 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 38423758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38423771 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 38423992 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 38423992 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 38424308 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 38424308 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 38424308 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 38424308 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 38427368 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 38427753 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 38427753 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 38427753 — Predictive Biomarker (PRD): DIS3 mRNA
Genes: DIS3; KIAA1008; RRP44
Study 38427753 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 38427753 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 38427930 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study 38428265 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 38428265 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 38428265 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 38428265 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 38428740 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38429056 — Surrogate Endpoint (SUR): Blood pressure
Study 38429253 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 38429311 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 38429311 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 38430084 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 38430272 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 38430375 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 38430375 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 38430375 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 38430413 — Surrogate Endpoint (SUR): Bone mineral density
Study 38430550 — Predictive Biomarker (PRD): HUNK mRNA
Genes: HUNK; MAKV
Study 38431043 — Predictive Biomarker (PRD): Microsatellite instability
Study 38431445 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 38432027 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 38432713 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 38433191 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 38433714 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 38433714 — Predictive Biomarker (PRD): Microsatellite instability
Study 38434639 — Safety Biomarker (SAF): IL-6 and IL-10
Study 38434770 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 38435072 — Surrogate Endpoint (SUR): Blood pressure
Study 38435072 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 38435286 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 38435978 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 38436365 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 38436589 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 38436589 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 38436824 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 38437725 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 38437725 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 38437725 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 38437868 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 38438427 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 38438735 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38438735 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 38438735 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 38439024 — Predictive Biomarker (PRD): ABCA3 mRNA
Genes: ABCA3; ABC3
Study 38439027 — Surrogate Endpoint (SUR): Blood pressure
Study 38439069 — Surrogate Endpoint (SUR): Blood pressure
Study 38440777 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 38441437 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 38441437 — Predictive Biomarker (PRD): EIF2AK3 mRNA
Genes: EIF2AK3; PEK; PERK
Study 38441437 — Predictive Biomarker (PRD): ULK1 mRNA
Genes: ULK1; KIAA0722
Study 38441437 — Predictive Biomarker (PRD): ATG13 mRNA
Genes: ATG13; KIAA0652
Study 38441437 — Predictive Biomarker (PRD): ATG5 mRNA
Genes: ATG5; APG5L; ASP
Study 38441437 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 38441437 — Predictive Biomarker (PRD): Induced myeloid leukemia cell differentiation protein Mcl-1
Genes: MCL1; BCL2L3
Study 38441897 — Surrogate Endpoint (SUR): Blood pressure
Study 38442809 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38442809 — Pharmacodynamic Biomarker (PDY): DNA topoisomerase I
Genes: TOP1
Study 38443660 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 38443693 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 38443835 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 38443944 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 38444034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38444034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 38444034 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Interleukin 6 receptor alpha
Genes: IL6R
Study 38444429 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 38444861 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 38445434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38445452 — Surrogate Endpoint (SUR): Serum creatinine
Study 38445487 — Predictive Biomarker (PRD): TANGO2 mRNA
Genes: TANGO2; C22orf25
Study 38445499 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 38446275 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38446275 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 38446316 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 38446316 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38446336 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 38446353 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 38446397 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38446419 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 38446568 — Predictive Biomarker (PRD): NBN mRNA
Genes: NBN; NBS; NBS1; P95
Study 38446792 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38446982 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 38447814 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 38448070 — Surrogate Endpoint (SUR): Blood pressure
Study 38448281 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 38448797 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 38449345 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38449767 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 38449916 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38450513 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 38451491 — Surrogate Endpoint (SUR): Forced vital capacity
Study 38452035 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study 38452035 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study 38452035 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study 38452035 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 38452035 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 38452035 — Predictive Biomarker (PRD): MRPL36 mRNA
Genes: MRPL36; BRIP1
Study 38452059 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 38452133 — Surrogate Endpoint (SUR): Bone mineral density
Study 38452207 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 38452207 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 38452327 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38452779 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 38452788 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 38453176 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 38453781 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38453781 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 38454132 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 38454468 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 38454482 — Predictive Biomarker (PRD): DNASE1 mRNA
Genes: DNASE1; DNL1; DRNI
Study 38455366 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 38455366 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38456289 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 38456620 — Monitoring Biomarker (MOI): HBV DNA
Study 38456660 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 38456660 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 38456703 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38457361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1