TrialPanorama/TrialPanorama-database huggingface dataset:
Study 36155516 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study 36155516 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36155516 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33501510 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 32101857 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 32101857 — Pharmacodynamic Biomarker (PDY): Interferon regulatory factor 3
Genes: IRF3
Study 32366577 — Surrogate Endpoint (SUR): Blood pressure
Study 32282706 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 35799657 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36273168 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 34284317 — Surrogate Endpoint (SUR): Blood pressure
Study 34284317 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 34284317 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35354280 — Predictive Biomarker (PRD): HM13 mRNA
Genes: HM13; H13; IMP1; PSL3; SPP; MSTP086
Study 33210178 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33210178 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 33210178 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32495646 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 32495646 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 32495646 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 32306525 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 36459910 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 34831764 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 34831764 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35014162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33538902 — Surrogate Endpoint (SUR): Blood pressure
Study 32615357 — Surrogate Endpoint (SUR): Blood pressure
Study 33778908 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33778908 — Surrogate Endpoint (SUR): Blood pressure
Study 33098411 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 33098411 — Predictive Biomarker (PRD): GCH1 mRNA
Genes: GCH1; DYT5; GCH
Study 33891380 — Predictive Biomarker (PRD): IL17F
Genes: IL-17F; ML-1; ML1
Study 33891380 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 34909045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34792161 — Surrogate Endpoint (SUR): Blood pressure
Study 33649613 — Surrogate Endpoint (SUR): Serum creatinine
Study 32073559 — Safety Biomarker (SAF): Hyaluronic acid
Study 34077998 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33646265 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 33646265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35191198 — Safety Biomarker (SAF): Hyaluronic acid
Study 34155684 — Surrogate Endpoint (SUR): Blood pressure
Study 36456480 — Surrogate Endpoint (SUR): Blood pressure
Study 32481277 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35553901 — Surrogate Endpoint (SUR): Blood pressure
Study 32045259 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 32045259 — Surrogate Endpoint (SUR): Blood pressure
Study 35714267 — Predictive Biomarker (PRD): PNN mRNA
Genes: PNN; DRS; MEMA
Study 33537902 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 33203003 — Surrogate Endpoint (SUR): Blood pressure
Study 32566763 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35584336 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35584336 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35584336 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32768551 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 35367282 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor delta
Genes: PPARD
Study 33429093 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 36495881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32854568 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 32854568 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 32544854 — Predictive Biomarker (PRD): ZNF804A mRNA
Genes: ZNF804A; C2orf10
Study 33684925 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 33684925 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 34347918 — Safety Biomarker (SAF): Hyaluronic acid
Study 34896568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34896568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33112250 — Surrogate Endpoint (SUR): Blood pressure
Study 35139274 — Surrogate Endpoint (SUR): Pathological complete response
Study 32452118 — Predictive Biomarker (PRD): BMPR2 mRNA
Genes: BMPR2; PPH1
Study 32452118 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34475255 — Surrogate Endpoint (SUR): Blood pressure
Study 35960487 — Predictive Biomarker (PRD): TYK2 mRNA
Genes: TYK2
Study 35691183 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 34555839 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 32164646 — Surrogate Endpoint (SUR): Blood pressure
Study 32334592 — Surrogate Endpoint (SUR): Blood pressure
Study 32334592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32334592 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34070377 — Surrogate Endpoint (SUR): Blood pressure
Study 33357505 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32948057 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 32500650 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32004775 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 33923171 — Surrogate Endpoint (SUR): Blood pressure
Study 32694162 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33779288 — Surrogate Endpoint (SUR): Serum sodium
Study 35114151 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study 34299697 — Safety Biomarker (SAF): BDNF
Study 32385058 — Surrogate Endpoint (SUR): Blood pressure
Study 32635612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32635612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34167881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 33587894 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34481561 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study 34153715 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32416008 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 35511454 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 33629461 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35555329 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35555329 — Surrogate Endpoint (SUR): Blood pressure
Study 32586396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32586396 — Monitoring Biomarker (MOI): Procalcitonin
Study 32586396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35896261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 34013428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34013428 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 616120483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32634745 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32067836 — Surrogate Endpoint (SUR): Blood pressure
Study 32933504 — Surrogate Endpoint (SUR): Serum uric acid
Study 32933504 — Surrogate Endpoint (SUR): Serum creatinine
Study 32933504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35263434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35263434 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 35263434 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 35263434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35263434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32086819 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 34807716 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32371430 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 32314971 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33986149 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 35317941 — Surrogate Endpoint (SUR): Blood pressure
Study 36200522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36200522 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 36200522 — Safety Biomarker (SAF): Interleukin 12
Study 36200522 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 36200522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36200522 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34378862 — Safety Biomarker (SAF): Interleukin 1
Study 35870710 — Surrogate Endpoint (SUR): Bone mineral density
Study 32534807 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32620337 — Surrogate Endpoint (SUR): Blood pressure
Study 35381839 — Surrogate Endpoint (SUR): Blood pressure
Study 33068344 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 33210787 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33430928 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34498822 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 35898575 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 34698704 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35240087 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 35307850 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 34896294 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34925204 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 32307089 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32307089 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 615803878 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 33891570 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 35971596 — Surrogate Endpoint (SUR): Serum potassium
Study 33279874 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33279874 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33279874 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33223005 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35849650 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 33877274 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 36089507 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 36089507 — Surrogate Endpoint (SUR): Blood pressure
Study 33926539 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 32532789 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 33630677 — Surrogate Endpoint (SUR): Blood pressure
Study 36385193 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 36385193 — Predictive Biomarker (PRD): PAX7 mRNA
Genes: PAX7; HUP1
Study 34263280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34263280 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35358015 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 32108027 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32108027 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32957817 — Surrogate Endpoint (SUR): Serum calcium
Study 34842343 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 34842343 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33069121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33069121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33069121 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33069121 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 33069121 — Safety Biomarker (SAF): BDNF
Study 32757086 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32324065 — Surrogate Endpoint (SUR): Blood pressure
Study 33057772 — Predictive Biomarker (PRD): AZIN2 mRNA
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 32738099 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 32361698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32361698 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 32265417 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 32265417 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 32265417 — Surrogate Endpoint (SUR): Serum creatinine
Study 32265417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32265417 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 32564128 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 33079705 — Surrogate Endpoint (SUR): Serum uric acid
Study 36182773 — Surrogate Endpoint (SUR): Blood pressure
Study 36214097 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33208014 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 33208014 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36281151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36281151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33402599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35842755 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 32823599 — Predictive Biomarker (PRD): LIPA mRNA
Genes: LIPA
Study 33322063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33322063 — Surrogate Endpoint (SUR): Serum uric acid
Study 33712965 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 33712965 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 35028615 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 35387431 — Surrogate Endpoint (SUR): Blood pressure
Study 36231330 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 36231330 — Predictive Biomarker (PRD): TFAM mRNA
Genes: TFAM; TCF6; TCF6L2
Study 36231330 — Predictive Biomarker (PRD): NRF1 mRNA
Genes: NRF1
Study 36231330 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 36231330 — Predictive Biomarker (PRD): PINK1 mRNA
Genes: PINK1
Study 32569239 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34316024 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 34851729 — Surrogate Endpoint (SUR): Blood pressure
Study 32544459 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 33617161 — Surrogate Endpoint (SUR): Bone mineral density
Study 35644305 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 35644305 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 35644305 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 35644305 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 33765257 — Surrogate Endpoint (SUR): Blood pressure
Study 33199044 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 32336236 — Surrogate Endpoint (SUR): Blood pressure
Study 33662615 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 36271471 — Surrogate Endpoint (SUR): Serum calcium
Study 32487594 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33794354 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33794354 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 35780589 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 35780589 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 35807864 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 35807864 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33188400 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 33188400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36314323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33851684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36184254 — Surrogate Endpoint (SUR): Blood pressure
Study 33227157 — Surrogate Endpoint (SUR): Blood pressure
Study 33760643 — Surrogate Endpoint (SUR): Blood pressure
Study 35627704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32768938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32768938 — Monitoring Biomarker (MOI): Procalcitonin
Study 32768938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32768938 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32768938 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35263343 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 35188180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35188180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35188180 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 34281470 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34281470 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32927753 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 33844425 — Surrogate Endpoint (SUR): Blood pressure
Study 34719731 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study 34719731 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 34193163 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34636710 — Surrogate Endpoint (SUR): Blood pressure
Study 36378671 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 33805883 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35578356 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 32115652 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 34381155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34381155 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34412750 — Monitoring Biomarker (MOI): Procalcitonin
Study 34412750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34412750 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer