TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33492568 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33492568 — Predictive Biomarker (PRD): Hormone receptor
Study 32057125 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34114623 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 34114623 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 34448875 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33180640 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 32157772 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33338988 — Surrogate Endpoint (SUR): Blood pressure
Study 32508327 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 33724296 — Surrogate Endpoint (SUR): Pathological complete response
Study 32820320 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 32820320 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34262263 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 35296483 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33136005 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 36424008 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33828257 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33026142 — Surrogate Endpoint (SUR): Blood pressure
Study 35255880 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35255880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35255880 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35255880 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35255880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35867702 — Monitoring Biomarker (MOI): HBV DNA
Study 33561041 — Surrogate Endpoint (SUR): Blood pressure
Study 32930112 — Predictive Biomarker (PRD): RHOH mRNA
Genes: RHOH; ARHH; TTF
Study 32930112 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 35979351 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 35979351 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 33326179 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33326179 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 33326179 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36322102 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 36501211 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 35397622 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35816053 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 35532871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36419388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32800842 — Surrogate Endpoint (SUR): Blood pressure
Study 35191173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35191173 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 35191173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33638931 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 33638931 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 33638931 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 33638931 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 36086254 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 34860287 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 34860287 — Safety Biomarker (SAF): Platelet to lymphocyte
Study 33637544 — Predictive Biomarker (PRD): LRIT1 mRNA
Genes: LRIT1; LRRC21; PAL
Study 33637544 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 33085967 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 32655132 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32561500 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 32561500 — Predictive Biomarker (PRD): MAML3 mRNA
Genes: MAML3; KIAA1816
Study 32561500 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 32561500 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 32561500 — Predictive Biomarker (PRD): OBSCN mRNA
Genes: OBSCN; KIAA1556; KIAA1639
Study 32561500 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33400792 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34283799 — Surrogate Endpoint (SUR): Blood pressure
Study 33779064 — Surrogate Endpoint (SUR): Blood pressure
Study 33779064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35927806 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33002437 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32609918 — Safety Biomarker (SAF): Hyaluronic acid
Study 34142638 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 36063974 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36063974 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 34274600 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 34900185 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34900185 — Safety Biomarker (SAF): BDNF
Study 33631355 — Surrogate Endpoint (SUR): Bone mineral density
Study 36422204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32066489 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 34167675 — Predictive Biomarker (PRD): IVL mRNA
Genes: IVL
Study 33915812 — Surrogate Endpoint (SUR): Blood pressure
Study 36281763 — Surrogate Endpoint (SUR): Blood pressure
Study 33655799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33655799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33936350 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 33936350 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 34587702 — Surrogate Endpoint (SUR): Blood pressure
Study 34587702 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34265777 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 33556963 — Surrogate Endpoint (SUR): Blood pressure
Study 32017923 — Surrogate Endpoint (SUR): Blood pressure
Study 36013168 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34702772 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 34833411 — Safety Biomarker (SAF): Hyaluronic acid
Study 32008947 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 33671257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35511887 — Surrogate Endpoint (SUR): Blood pressure
Study 32823974 — Safety Biomarker (SAF): Reactive oxygen species
Study 33413588 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35533220 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35533220 — Surrogate Endpoint (SUR): Blood pressure
Study 35533220 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32052313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32567438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32567438 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36145064 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 32424935 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 32424935 — Surrogate Endpoint (SUR): Blood pressure
Study 35545225 — Surrogate Endpoint (SUR): Serum sodium
Study 33477443 — Surrogate Endpoint (SUR): Blood pressure
Study 33322022 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 33322022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35115208 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35115208 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32696258 — Surrogate Endpoint (SUR): Blood pressure
Study 32818647 — Safety Biomarker (SAF): Reactive oxygen species
Study 33191851 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 32727831 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35902817 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33076714 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 33076714 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 33810796 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33250314 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35936217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35936217 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 35936217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35936217 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34192396 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 34192396 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 34791423 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 33004131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35686864 — Safety Biomarker (SAF): Hyaluronic acid
Study 34023151 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 34730863 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 34919774 — Surrogate Endpoint (SUR): Blood pressure
Study 34919774 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33683313 — Surrogate Endpoint (SUR): Blood pressure
Study 32533622 — Surrogate Endpoint (SUR): Blood pressure
Study 36356631 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36356631 — Surrogate Endpoint (SUR): Blood pressure
Study 36120593 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36120593 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36120593 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34498388 — Surrogate Endpoint (SUR): Blood pressure
Study 34645170 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34645170 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33808030 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 33808030 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34023513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35292055 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 35292055 — Surrogate Endpoint (SUR): Serum uric acid
Study 34555158 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34686108 — Predictive Biomarker (PRD): GMIP mRNA
Genes: GMIP
Study 33091192 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 33150559 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32396189 — Surrogate Endpoint (SUR): Blood pressure
Study 32396189 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 32802039 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32802039 — Surrogate Endpoint (SUR): Blood pressure
Study 33899259 — Surrogate Endpoint (SUR): Probing pocket depth
Study 34750069 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35085506 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35722726 — Surrogate Endpoint (SUR): Blood pressure
Study 32915236 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32915236 — Surrogate Endpoint (SUR): Blood pressure
Study 33438085 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 35487525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35487525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35195932 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 35195932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34461975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34461975 — Surrogate Endpoint (SUR): Blood pressure
Study 34461975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32366238 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 34228250 — Surrogate Endpoint (SUR): Total kidney volume
Study 33693561 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33693561 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 33693561 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 33693561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33190008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33753456 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36175982 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 33766132 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 32804611 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32634760 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32634760 — Predictive Biomarker (PRD): Hormone receptor
Study 35658325 — Surrogate Endpoint (SUR): Bone mineral density
Study 32915427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32374123 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 34783204 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 36464918 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 35439029 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34407273 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34570053 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33127634 — Surrogate Endpoint (SUR): Serum potassium
Study 35378105 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 35378105 — Safety Biomarker (SAF): BDNF
Study 35426564 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 35126621 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32065827 — Surrogate Endpoint (SUR): Blood pressure
Study 33813930 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33813930 — Surrogate Endpoint (SUR): Blood pressure
Study 32693009 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32693009 — Safety Biomarker (SAF): BDNF
Study 33599975 — Safety Biomarker (SAF): DRD2
Study 32233095 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 34099268 — Surrogate Endpoint (SUR): Blood pressure
Study 35858876 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33465506 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 33465506 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 33609340 — Surrogate Endpoint (SUR): Blood pressure
Study 34097856 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 36137622 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 32211953 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 35610015 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 33045287 — Surrogate Endpoint (SUR): Blood pressure
Study 32912983 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33813110 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34519561 — Surrogate Endpoint (SUR): Blood pressure
Study 35869725 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 35869725 — Predictive Biomarker (PRD): IL1R1 mRNA
Genes: IL1R1; IL1R; IL1RA; IL1RT1
Study 34736731 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32270639 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 33300039 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33300039 — Surrogate Endpoint (SUR): Blood pressure
Study 32800909 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 36072904 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 36072904 — Predictive Biomarker (PRD): ERLEC1 mRNA
Genes: ERLEC1; C2orf30; XTP3TPB; UNQ1878/PRO4321
Study 36072904 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 33562015 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33131908 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33593886 — Predictive Biomarker (PRD): TAP1 mRNA
Genes: TAP1; ABCB2; PSF1; RING4; Y3
Study 33593886 — Predictive Biomarker (PRD): GBP1 mRNA
Genes: GBP1
Study 33593886 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 33593886 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 33593886 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 33593886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 33593886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 34874478 — Predictive Biomarker (PRD): SSTR2 mRNA
Genes: SSTR2
Study 36235575 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33359750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33359750 — Predictive Biomarker (PRD): PTGIS mRNA
Genes: PTGIS; CYP8; CYP8A1
Study 32348531 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32348531 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32473365 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 35049196 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35049196 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32133606 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 35754258 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 34107553 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 33226202 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 33670235 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 34817396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34817396 — Surrogate Endpoint (SUR): Blood pressure
Study 36438978 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 36438978 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32572439 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 32915777 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 32915777 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 32915777 — Predictive Biomarker (PRD): APOC1 mRNA
Genes: APOC1
Study 32915777 — Monitoring Biomarker (MOI): Apolipoprotein C-II
Genes: APOC2; APC2
Study 32915777 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 32915777 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 32915777 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35180097 — Surrogate Endpoint (SUR): Bone mineral density
Study 35180097 — Surrogate Endpoint (SUR): Serum calcium
Study 34625598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34625598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34625598 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 32682507 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 36397122 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34444656 — Surrogate Endpoint (SUR): Blood pressure
Study 32047952 — Surrogate Endpoint (SUR): Blood pressure
Study 36201455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36201455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34189135 — Safety Biomarker (SAF): Hyaluronic acid
Study 35025817 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35256899 — Surrogate Endpoint (SUR): Blood pressure