TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT06550167 — Safety Biomarker (SAF): BDNF
Study NCT06550167 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05274646 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study NCT00215007 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study NCT05444712 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05398614 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT05763589 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06440122 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study NCT06427096 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05186922 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06538051 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06327321 — Predictive Biomarker (PRD): TYK2 mRNA
Genes: TYK2
Study NCT06249178 — Predictive Biomarker (PRD): ALPP mRNA
Genes: ALPP; PLAP
Study NCT06127446 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT04087889 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT05565807 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT04668716 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04668716 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study NCT05533749 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04802343 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06096701 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06182618 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06543771 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT04758962 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04798287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04880005 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06225284 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06225284 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06225284 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT06614777 — Predictive Biomarker (PRD): ATP2A2 mRNA
Genes: ATP2A2; ATP2B
Study NCT06712186 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05874388 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study NCT04633590 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06730165 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06731491 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06393335 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05364333 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT05364333 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2
Study NCT06411093 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05996536 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00764543 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05912933 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05011019 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT06112041 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05518383 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06348654 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00000805 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05482087 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05294770 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05621525 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05733234 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT05733234 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT04916314 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06545526 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT06701643 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT05433480 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study NCT05433480 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05433480 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05055492 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05877131 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05922839 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05577000 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04772248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06341621 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05130866 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT06221345 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06243185 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06243185 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06243185 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05795517 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05112731 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT04613986 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT04613986 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT06174025 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04287543 — Predictive Biomarker (PRD): PER1 mRNA
Genes: PER1; KIAA0482; PER; RIGUI
Study NCT04287543 — Predictive Biomarker (PRD): BMAL1 mRNA
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study NCT06300138 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT06300138 — Predictive Biomarker (PRD): STIM1 mRNA
Genes: STIM1; GOK
Study NCT00000984 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05873400 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study NCT05668611 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study NCT05948865 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05929573 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT05929573 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05929573 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT06623396 — Predictive Biomarker (PRD): MSLN mRNA
Genes: MSLN; MPF
Study NCT06748989 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04548843 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04548843 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT06214988 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study NCT05787600 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05787600 — Safety Biomarker (SAF): Interleukin 1
Study NCT05787600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05072444 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study NCT00000844 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06432738 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study NCT04757363 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04757363 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04821050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05792410 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05818319 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT05079152 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05079152 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05668988 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05668988 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06289205 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT05662670 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05807048 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study NCT03634488 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05038137 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT05867615 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06291935 — Predictive Biomarker (PRD): CNGA1 mRNA
Genes: CNGA1; CNCG; CNCG1
Study NCT05920785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05920785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05830669 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT04212143 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04133077 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05435820 — Safety Biomarker (SAF): Cytochrome c
Study NCT05219409 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT05229497 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05229497 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study NCT05179343 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06236139 — Predictive Biomarker (PRD): STEAP1 mRNA
Genes: STEAP1; PRSS24; STEAP
Study NCT05252910 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05488821 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT05011487 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06156527 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06156527 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06279923 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06279923 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT06537167 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05548439 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06539806 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT05538195 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04992858 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05658757 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05868915 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT00002084 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04672954 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study NCT06011512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06011512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05099094 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05049798 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT05596266 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study NCT06635148 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05891548 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05891548 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04858178 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05247528 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04911192 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05402371 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study NCT05165433 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT04657822 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05046496 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06071065 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04121299 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05585255 — Predictive Biomarker (PRD): DKK2 mRNA
Genes: DKK2; UNQ682/PRO1316
Study NCT05715606 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06042673 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05885633 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT06442202 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study NCT06334406 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study NCT06178614 — Predictive Biomarker (PRD): ENPP3 mRNA
Genes: ENPP3; PDNP3
Study NCT05028751 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study NCT05028751 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05596383 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT05596383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05396443 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05088889 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT06260709 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT05557253 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06095089 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06095089 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT06095089 — Predictive Biomarker (PRD): KLK2 mRNA
Genes: KLK2
Study NCT05315817 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06530160 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT05758779 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT05758779 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05972070 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05076747 — Safety Biomarker (SAF): BDNF
Study NCT04978558 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06410040 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05590117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05590117 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT05485961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04415424 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05408793 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study NCT06065098 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04331041 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study NCT06069661 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study NCT06147960 — Predictive Biomarker (PRD): XIAP mRNA
Genes: XIAP; API3; BIRC4; IAP3
Study NCT05472857 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT05432531 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT05305014 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT06302257 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT05434910 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04902235 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT04911621 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT05415826 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT04671472 — Predictive Biomarker (PRD): GNE mRNA
Genes: GNE; GLCNE
Study NCT06422078 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06052956 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04954313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05199584 — Predictive Biomarker (PRD): Protein patched homolog 1
Genes: PTCH1; PTCH
Study NCT06247553 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05284201 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study NCT05173584 — Surrogate Endpoint (SUR): Serum potassium
Study NCT06343090 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06343090 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT04785833 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT04785833 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT06529081 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06529081 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06529081 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06448195 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06448195 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06529172 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00416429 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT06654297 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05857670 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06608602 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05683353 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05582551 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study NCT05955170 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06730204 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT06730217 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06731842 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05282290 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06425848 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT04955678 — Surrogate Endpoint (SUR): Serum potassium
Study NCT04690699 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05218629 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06310148 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06730347 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study NCT05249062 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05683717 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05966337 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study NCT05374772 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05541627 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT04837040 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study NCT05537025 — Predictive Biomarker (PRD): MMP7 mRNA
Genes: MMP7; MPSL1; PUMP1
Study NCT06286423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06626113 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06626113 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT05051956 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06625970 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05453292 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT05453292 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study NCT06391645 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT06413355 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT06763744 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT06721442 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05389488 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04951167 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04594642 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05265767 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT06064409 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05413434 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05413434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05413434 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05413434 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05115344 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT05115344 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05115344 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study NCT06126640 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05936762 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04945330 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT05630794 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT06103721 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05526300 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06080568 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT06080568 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study NCT06188494 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06247202 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT06247202 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study NCT06247202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2