TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33359367 — Safety Biomarker (SAF): BDNF
Study 34649978 — Predictive Biomarker (PRD): P2RX2 mRNA
Genes: P2RX2; P2X2
Study 34976108 — Surrogate Endpoint (SUR): Blood pressure
Study 34119469 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34119469 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33870752 — Surrogate Endpoint (SUR): Blood pressure
Study 35609059 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33235447 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 32706343 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 35809362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33771116 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 32699287 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32699287 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 32699287 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 32299733 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 33959750 — Predictive Biomarker (PRD): LAT2 mRNA
Genes: LAT2; LAB; NTAL; WBS15; WBSCR15; WBSCR5; HSPC046
Study 35453121 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 33048477 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34429160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35289857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35289857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32892245 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32816144 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32236398 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 36087550 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 36087550 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33166722 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36378077 — Surrogate Endpoint (SUR): Blood pressure
Study 32698233 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 35758031 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 35758031 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35758031 — Surrogate Endpoint (SUR): Blood pressure
Study 35758031 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 36063401 — Surrogate Endpoint (SUR): Total kidney volume
Study 32203980 — Surrogate Endpoint (SUR): Serum creatinine
Study 32060825 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 32060825 — Predictive Biomarker (PRD): HM13 mRNA
Genes: HM13; H13; IMP1; PSL3; SPP; MSTP086
Study 34855329 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34855329 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36447243 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34391232 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 32384147 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 35997833 — Safety Biomarker (SAF): Hyaluronic acid
Study 34474163 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 33661437 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 36064382 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 34486986 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 34802471 — Surrogate Endpoint (SUR): Blood pressure
Study 35396587 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33536102 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35714357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35037116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35037116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35037116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33105353 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 33105353 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 33319566 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 33319566 — Surrogate Endpoint (SUR): Blood pressure
Study 34644395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32200813 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32200813 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32998731 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 36894666 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 32779375 — Safety Biomarker (SAF): Hyaluronic acid
Study 32776763 — Safety Biomarker (SAF): Hyaluronic acid
Study 32733445 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 35209777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36139151 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 36139151 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 35791083 — Surrogate Endpoint (SUR): Blood pressure
Study 32649326 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 616443500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 35781184 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33667442 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 35952629 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 32867965 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32867965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34528220 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33844587 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 36399969 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34260948 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 34260948 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 36114491 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 34948547 — Surrogate Endpoint (SUR): Blood pressure
Study 32484228 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 32484228 — Predictive Biomarker (PRD): IGFBP5 mRNA
Genes: IGFBP5; IBP5
Study 35134661 — Surrogate Endpoint (SUR): Blood pressure
Study 33902621 — Safety Biomarker (SAF): Interleukin 1
Study 36231972 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 36148821 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36294490 — Surrogate Endpoint (SUR): Blood pressure
Study 36294490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35553373 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 32770402 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32770402 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32243070 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 32243070 — Surrogate Endpoint (SUR): Serum calcium
Study 32149711 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 34957632 — Surrogate Endpoint (SUR): Blood pressure
Study 34670042 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 36472870 — Predictive Biomarker (PRD): ST8SIA4 mRNA
Genes: ST8SIA4; PST; PST1; SIAT8D
Study 36472870 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 36472870 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 33627215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33627215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34495337 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 35602349 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35191790 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35191790 — Surrogate Endpoint (SUR): Blood pressure
Study 34107720 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33369253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33369253 — Surrogate Endpoint (SUR): Blood pressure
Study 33369253 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 33369253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33741520 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 33741520 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 33741520 — Predictive Biomarker (PRD): TFAM mRNA
Genes: TFAM; TCF6; TCF6L2
Study 33741520 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 33741520 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 35550854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33832490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33832490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34257352 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33070366 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 33070366 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35385050 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 35385050 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 35385050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35954937 — Predictive Biomarker (PRD): FSTL1 mRNA
Genes: FSTL1; FRP
Study 35954937 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33533155 — Safety Biomarker (SAF): Hyaluronic acid
Study 34528408 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 36036106 — Safety Biomarker (SAF): IL-6 and IL-10
Study 36036106 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 36036106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36036106 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32677847 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 33139757 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33952318 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32649856 — Predictive Biomarker (PRD): GRK5 mRNA
Genes: GRK5; GPRK5
Study 35427476 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 35427476 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 35427476 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34508693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33760027 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32792320 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 32408245 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 35930287 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33253306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33253306 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34516692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35114141 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32228743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35652829 — Surrogate Endpoint (SUR): Blood pressure
Study 34102137 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34137783 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34137783 — Predictive Biomarker (PRD): Hormone receptor
Study 33901870 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33901870 — Predictive Biomarker (PRD): CD8A mRNA
Genes: CD8A; MAL
Study 35025151 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32839195 — Surrogate Endpoint (SUR): Serum creatinine
Study 32839195 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 32434204 — Surrogate Endpoint (SUR): Serum creatinine
Study 32349752 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 35094679 — Monitoring Biomarker (MOI): Cell-free DNA
Study 35094679 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 32655024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32598244 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 35314714 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 35314714 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33377700 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 36018356 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 33751956 — Surrogate Endpoint (SUR): Blood pressure
Study 35676163 — Surrogate Endpoint (SUR): Bone mineral density
Study 32370540 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34259202 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35037328 — Surrogate Endpoint (SUR): Blood pressure
Study 34449265 — Surrogate Endpoint (SUR): Blood pressure
Study 32640130 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35145761 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 35222688 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36220067 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32157250 — Surrogate Endpoint (SUR): Blood pressure
Study 35098587 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 35098587 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 36342143 — Surrogate Endpoint (SUR): Blood pressure
Study 33248629 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33508442 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 33508442 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32391740 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33884643 — Surrogate Endpoint (SUR): Blood pressure
Study 33577964 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 35986739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35986739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35986739 — Monitoring Biomarker (MOI): Procalcitonin
Study 35296532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34779272 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33922493 — Surrogate Endpoint (SUR): Blood pressure
Study 33922493 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33267610 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 32040761 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34364386 — Surrogate Endpoint (SUR): Blood pressure
Study 35441200 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32507430 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 33966730 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 35686330 — Surrogate Endpoint (SUR): Blood pressure
Study 33031757 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 33031757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35996236 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33978491 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33978491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33978491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33978491 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33978491 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33475743 — Predictive Biomarker (PRD): NRM mRNA
Genes: NRM; NRM29; UNQ555/PRO1112
Study 33503305 — Predictive Biomarker (PRD): NEDD8 mRNA
Genes: NEDD8
Study 33829308 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 32005282 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 33064057 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 33438437 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33472855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33472855 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33472855 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32243492 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 32243492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32243492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32960408 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 32960408 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33581798 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 32380119 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 32380119 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33722330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33371148 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 32826635 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 32826635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32826635 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 35063214 — Predictive Biomarker (PRD): PTRH2 mRNA
Genes: PTRH2; BIT1; PTH2; CGI-147
Study 34175968 — Surrogate Endpoint (SUR): Blood pressure
Study 34882076 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study 35341011 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 33856748 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 32371433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36163869 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 36163869 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 36129535 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 36129535 — Surrogate Endpoint (SUR): Blood pressure
Study 33231879 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 32896291 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36007135 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34704970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32200659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35319989 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32092518 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32092518 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33671082 — Surrogate Endpoint (SUR): Blood pressure
Study 32531482 — Surrogate Endpoint (SUR): Forced vital capacity