TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32711519 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32711519 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 35722469 — Surrogate Endpoint (SUR): Blood pressure
Study 32497714 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 35232402 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32369446 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35443107 — Surrogate Endpoint (SUR): Blood pressure
Study 36192769 — Surrogate Endpoint (SUR): Blood pressure
Study 32729887 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 32729887 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 32729887 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33436106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33436106 — Safety Biomarker (SAF): IL-6 and IL-10
Study 34883524 — Surrogate Endpoint (SUR): Blood pressure
Study 36099211 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 34487875 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 34487875 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34755014 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 33464392 — Surrogate Endpoint (SUR): Bone mineral density
Study 35039260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35039260 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 35039260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33739487 — Surrogate Endpoint (SUR): Blood pressure
Study 33277091 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32768331 — Safety Biomarker (SAF): Reactive oxygen species
Study 32768331 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34918332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32942043 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 36163930 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 34540641 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34540641 — Surrogate Endpoint (SUR): Blood pressure
Study 33107596 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 33107596 — Surrogate Endpoint (SUR): Probing pocket depth
Study 36376887 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 36376887 — Predictive Biomarker (PRD); Safety Biomarker (SAF): BHMT mRNA
Genes: BHMT
Study 32097165 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 32956756 — Predictive Biomarker (PRD): FIP1L1 mRNA
Genes: FIP1L1; FIP1; RHE
Study 32956756 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 35451391 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35917052 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35917052 — Predictive Biomarker (PRD): Hormone receptor
Study 35917052 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35917052 — Surrogate Endpoint (SUR): Pathological complete response
Study 33546947 — Safety Biomarker (SAF): Netrin-1
Genes: NTN1; NTN1L
Study 33306989 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32788190 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 33779698 — Predictive Biomarker (PRD): MBTPS1 mRNA
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 35441218 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 32816895 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study 32816895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32816895 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 33470739 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 33612595 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35229945 — Predictive Biomarker (PRD): GRIK1 mRNA
Genes: GRIK1; GLUR5
Study 33733965 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 36052812 — Surrogate Endpoint (SUR): Blood pressure
Study 32115470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33407269 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 34886576 — Surrogate Endpoint (SUR): Blood pressure
Study 33504485 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 33504485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33504485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32882036 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 33482045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33482045 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 35215521 — Surrogate Endpoint (SUR): Serum calcium
Study 33847325 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 33847325 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 33150187 — Predictive Biomarker (PRD): CPT1A mRNA
Genes: CPT1A; CPT1
Study 33300323 — Surrogate Endpoint (SUR): Blood pressure
Study 32992062 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 33321447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33321447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33321447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34794285 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 34794285 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 35943798 — Predictive Biomarker (PRD): SFRP2 mRNA
Genes: SFRP2; FRP2; SARP1; FKSG12; UNQ361/PRO697
Study 35943798 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 35943798 — Predictive Biomarker (PRD): MYOC mRNA
Genes: MYOC; GLC1A; TIGR
Study 35943798 — Safety Biomarker (SAF): C-C motif chemokine 19
Genes: CCL19; ELC; MIP3B; SCYA19
Study 35943798 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 35244287 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 32961353 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 33637048 — Predictive Biomarker (PRD): SMAD3 mRNA
Genes: SMAD3; MADH3
Study 33637048 — Predictive Biomarker (PRD): PRKACB mRNA
Genes: PRKACB
Study 33637048 — Predictive Biomarker (PRD): miR-145
Genes: MIR145
Study 33637048 — Predictive Biomarker (PRD): miR-101-3p
Study 33580297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32358874 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32205274 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32205274 — Surrogate Endpoint (SUR): Blood pressure
Study 32822286 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 32822286 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 32854231 — Predictive Biomarker (PRD): TLR1 mRNA
Genes: TLR1; KIAA0012
Study 32854231 — Predictive Biomarker (PRD): TLR5 mRNA
Genes: TLR5; TIL3
Study 32854231 — Predictive Biomarker (PRD): TLR8 mRNA
Genes: TLR8; UNQ249/PRO286
Study 32854231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33687747 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 33687747 — Predictive Biomarker (PRD): ELF3 mRNA
Genes: ELF3; ERT; ESX; JEN
Study 34608333 — Surrogate Endpoint (SUR): Pathological complete response
Study 34774360 — Predictive Biomarker (PRD): ST6GAL1 mRNA
Genes: ST6GAL1; SIAT1
Study 32241795 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 33295693 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34162752 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 32895247 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 33503332 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 32645234 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35795564 — Surrogate Endpoint (SUR): Blood pressure
Study 33917916 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33917916 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33917916 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34543267 — Surrogate Endpoint (SUR): Blood pressure
Study 36619724 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 36619724 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 36619724 — Predictive Biomarker (PRD): FBXO8 mRNA
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 36619724 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32567544 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 32567544 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 32567544 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32567544 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 35468325 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 32563025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32563025 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32563025 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 32376732 — Surrogate Endpoint (SUR): Blood pressure
Study 35581902 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34847841 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 33723721 — Surrogate Endpoint (SUR): Blood pressure
Study 36028376 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 34237697 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 36118671 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 36118671 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33742159 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 34600123 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33054695 — Surrogate Endpoint (SUR): Blood pressure
Study 33765335 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 33765335 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 33765335 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 33765335 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 33765335 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 33765335 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 33530248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32164762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36450211 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 34155812 — Surrogate Endpoint (SUR): Serum creatinine
Study 34155812 — Surrogate Endpoint (SUR): Blood pressure
Study 34195577 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 34195577 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35180719 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 33004392 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 33004392 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 36078628 — Safety Biomarker (SAF): Hyaluronic acid
Study 32493115 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 32493115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32493115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32366578 — Surrogate Endpoint (SUR): Blood pressure
Study 34587302 — Monitoring Biomarker (MOI): HBV DNA
Study 34587302 — Surrogate Endpoint (SUR): Bone mineral density
Study 34587302 — Surrogate Endpoint (SUR): Serum creatinine
Study 35840273 — Surrogate Endpoint (SUR): Blood pressure
Study 34514929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35931879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32690074 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 34324433 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33966396 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34794236 — Predictive Biomarker (PRD): ACKR3 mRNA
Genes: ACKR3; CMKOR1; CXCR7; GPR159; RDC1
Study 34794236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 34794236 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 33780099 — Surrogate Endpoint (SUR): Blood pressure
Study 32692216 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32692216 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 36459768 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34749549 — Surrogate Endpoint (SUR): Blood pressure
Study 36109766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33509602 — Surrogate Endpoint (SUR): Blood pressure
Study 33509602 — Surrogate Endpoint (SUR): Serum creatinine
Study 32568429 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35150143 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 36199630 — Surrogate Endpoint (SUR): Blood pressure
Study 32572778 — Surrogate Endpoint (SUR): Blood pressure
Study 32893372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33727428 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 36104971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36074703 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 35421019 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34719994 — Predictive Biomarker (PRD): SPX mRNA
Genes: SPX; C12orf39
Study 33306586 — Surrogate Endpoint (SUR): Serum testosterone
Study 32285955 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 32932175 — Safety Biomarker (SAF): Reactive oxygen species
Study 33387920 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33387920 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32430459 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 32430459 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34769814 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34769814 — Safety Biomarker (SAF): BDNF
Study 33463497 — Surrogate Endpoint (SUR): Blood pressure
Study 33463497 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33463497 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 33463497 — Surrogate Endpoint (SUR): Serum creatinine
Study 35941373 — Predictive Biomarker (PRD): SEMA4D mRNA
Genes: SEMA4D; C9orf164; CD100; SEMAJ
Study 35941373 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 33764324 — Surrogate Endpoint (SUR): Blood pressure
Study 35737919 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34647600 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 32618212 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 33183668 — Predictive Biomarker (PRD): BMI1 mRNA
Genes: BMI1; PCGF4; RNF51
Study 35636696 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36156930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33079474 — Surrogate Endpoint (SUR): Blood pressure
Study 37003126 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 32847444 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36203988 — Safety Biomarker (SAF): Platelet to lymphocyte
Study 36203988 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 34587943 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34864737 — Surrogate Endpoint (SUR): Bone mineral density
Study 34004482 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32655129 — Predictive Biomarker (PRD): FOXA2 mRNA
Genes: FOXA2; HNF3B; TCF3B
Study 32655129 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 32655129 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 32484129 — Surrogate Endpoint (SUR): Serum creatinine
Study 32484129 — Surrogate Endpoint (SUR): Serum potassium
Study 32957571 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34330599 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33694338 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 33757513 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36273314 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 36361434 — Surrogate Endpoint (SUR): Bone mineral density
Study 32367059 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 32367059 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 32367059 — Predictive Biomarker (PRD): DRD1 mRNA
Genes: DRD1
Study 32064729 — Predictive Biomarker (PRD): KLF11 mRNA
Genes: KLF11; FKLF; TIEG2
Study 35486196 — Predictive Biomarker (PRD): APOBEC3C mRNA
Genes: APOBEC3C; APOBEC1L; PBI
Study 35272176 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32986828 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32986828 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32986828 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 32986828 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32986828 — Predictive Biomarker (PRD): Hormone receptor
Study 33874955 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 33655978 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 36018547 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33981141 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33115517 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 34142111 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 32517806 — Surrogate Endpoint (SUR): Blood pressure
Study 32127283 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33916940 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33916940 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33916940 — Surrogate Endpoint (SUR): Blood pressure
Study 33933853 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 36342475 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 32447856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32447856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34757701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34757701 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 34757701 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34757701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33724614 — Predictive Biomarker (PRD): miR-17
Genes: MIR17
Study 33724614 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study 34338469 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32013830 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 32013830 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 32013830 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32169149 — Monitoring Biomarker (MOI): Procalcitonin
Study 32169149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32169149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32578353 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 34511330 — Pharmacodynamic Biomarker (PDY): C-type lectin domain family 4 member C
Genes: CLEC4C; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; UNQ9361/PRO34150
Study 35215772 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36108657 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35500422 — Surrogate Endpoint (SUR): Blood pressure
Study 33894554 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 35727053 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2