TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35895759 — Surrogate Endpoint (SUR): Blood pressure
Study 33219618 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33219618 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 33219618 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 33219618 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study 33219618 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 33219618 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 33219618 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 33219618 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33219618 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 33219618 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study 33219618 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 36322461 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32940751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33601388 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 35880281 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 35880281 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 35880281 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 33513879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 34751591 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34751591 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34751591 — Predictive Biomarker (PRD): Hormone receptor
Study 35836102 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35689489 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 35689489 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 35689489 — Predictive Biomarker (PRD): CALCA mRNA
Genes: CALCA; CALC1
Study 35689489 — Predictive Biomarker (PRD): REG1A mRNA
Genes: REG1A; PSPS; PSPS1; REG
Study 35689489 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 35689489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32618695 — Surrogate Endpoint (SUR): Serum creatinine
Study 36573450 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 34773261 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 33080017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33080017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33516014 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34106648 — Surrogate Endpoint (SUR): Blood pressure
Study 33208739 — Surrogate Endpoint (SUR): Blood pressure
Study 33927126 — Surrogate Endpoint (SUR): Bone mineral density
Study 33927126 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 33927126 — Surrogate Endpoint (SUR): Serum calcium
Study 33743283 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 36137626 — Safety Biomarker (SAF): BDNF
Study 35677096 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35725294 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 32163637 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 32163637 — Surrogate Endpoint (SUR): Bone mineral density
Study 32163637 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32163637 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35659704 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 35659704 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35659704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32102506 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33176381 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34808751 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34494931 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 32585332 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 32585332 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 33871596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36472197 — Surrogate Endpoint (SUR): Blood pressure
Study 32345650 — Surrogate Endpoint (SUR): Blood pressure
Study 36004368 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 36004368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36004368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35894681 — Surrogate Endpoint (SUR): Blood pressure
Study 35856361 — Surrogate Endpoint (SUR): Sperm parameters
Study 35856361 — Surrogate Endpoint (SUR): Serum testosterone
Study 35295200 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32622071 — Predictive Biomarker (PRD): DLK1 mRNA
Genes: DLK1; DLK
Study 32622071 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34772324 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 34543068 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35133617 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33546622 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 33624806 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 33742316 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 33398922 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 35619283 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 32178668 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 34638611 — Predictive Biomarker (PRD): DUSP6 mRNA
Genes: DUSP6; MKP3; PYST1
Study 33577618 — Predictive Biomarker (PRD): ASPSCR1 mRNA
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 36266431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33782049 — Predictive Biomarker (PRD): TFF2 mRNA
Genes: TFF2; SML1
Study 33782049 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study 33782049 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 33782049 — Predictive Biomarker (PRD): PAX9 mRNA
Genes: PAX9
Study 33782049 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 33782049 — Predictive Biomarker (PRD): MUC2 mRNA
Genes: MUC2; SMUC
Study 33782049 — Safety Biomarker (SAF): Fatty acid binding protein 1
Genes: FABP1; FABPL
Study 33782049 — Predictive Biomarker (PRD): CDX1 mRNA
Genes: CDX1
Study 32236953 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 32893790 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32893790 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 35712800 — Surrogate Endpoint (SUR): Blood pressure
Study 35712800 — Surrogate Endpoint (SUR): Serum creatinine
Study 35032224 — Surrogate Endpoint (SUR): Blood pressure
Study 34256199 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 34817321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34817321 — Surrogate Endpoint (SUR): Blood pressure
Study 34791009 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 35565929 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 35565929 — Predictive Biomarker (PRD): SLC2A5 mRNA
Genes: SLC2A5; GLUT5
Study 35565929 — Predictive Biomarker (PRD): SLC2A2 mRNA
Genes: SLC2A2; GLUT2
Study 35565929 — Predictive Biomarker (PRD): HMGCS2 mRNA
Genes: HMGCS2
Study 35565929 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 34980609 — Surrogate Endpoint (SUR): Blood pressure
Study 33271319 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 36055978 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 36055978 — Predictive Biomarker (PRD): HTR3A mRNA
Genes: HTR3A; 5HT3R; HTR3
Study 36004653 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 32291277 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 35410292 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34383954 — Surrogate Endpoint (SUR): Serum uric acid
Study 35551086 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 34086911 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33579804 — Predictive Biomarker (PRD): SSTR2 mRNA
Genes: SSTR2
Study 35698432 — Predictive Biomarker (PRD): FANCC
Genes: FAC; FA3
Study 34670215 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34670215 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 34670215 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 34670215 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 34670215 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36216089 — Surrogate Endpoint (SUR): Blood pressure
Study 34002944 — Predictive Biomarker (PRD): SMAD4 mRNA
Genes: SMAD4; DPC4; MADH4
Study 32465510 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 32465510 — Predictive Biomarker (PRD): CD9 mRNA
Genes: CD9; MIC3; TSPAN29; GIG2
Study 32465510 — Predictive Biomarker (PRD): CD81 mRNA
Genes: CD81; TAPA1; TSPAN28
Study 32465510 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study 32842812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33491528 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33023661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32702849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32702849 — Monitoring Biomarker (MOI): Procalcitonin
Study 32702849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35298060 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35298060 — Surrogate Endpoint (SUR): Blood pressure
Study 36333720 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34022051 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 34022051 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34933950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32383366 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 32387453 — Safety Biomarker (SAF): Epiregulin
Genes: EREG
Study 32387453 — Safety Biomarker (SAF): Amphiregulin
Genes: AREG; AREGB; SDGF
Study 32387453 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 32160019 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 35701094 — Predictive Biomarker (PRD): LAMB2 mRNA
Genes: LAMB2; LAMS
Study 35770339 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 34174082 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 36027311 — Surrogate Endpoint (SUR): Blood pressure
Study 32505529 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 32505529 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 33740926 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 33740926 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 32223057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33685923 — Surrogate Endpoint (SUR): Blood pressure
Study 32093379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35900311 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 35900311 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 34167897 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34167897 — Predictive Biomarker (PRD): CNTNAP3 mRNA
Genes: CNTNAP3; CASPR3; KIAA1714
Study 34167897 — Predictive Biomarker (PRD): CNTN4 mRNA
Genes: CNTN4
Study 34167897 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 34167897 — Predictive Biomarker (PRD): TNXB mRNA
Genes: TNXB; HXBL; TNX; TNXB1; TNXB2; XB
Study 34167897 — Predictive Biomarker (PRD): CTSE mRNA
Genes: CTSE
Study 34167897 — Predictive Biomarker (PRD): OLFM4 mRNA
Genes: OLFM4; GW112; UNQ362/PRO698
Study 34167897 — Predictive Biomarker (PRD): KRT5 mRNA
Genes: KRT5
Study 34167897 — Predictive Biomarker (PRD): KRT6A mRNA
Genes: KRT6A; K6A; KRT6D
Study 34167897 — Predictive Biomarker (PRD): IDO2 mRNA
Genes: IDO2; INDOL1
Study 32299845 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34089122 — Surrogate Endpoint (SUR): Total kidney volume
Study 32641220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32641220 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 36319521 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36319521 — Surrogate Endpoint (SUR): Blood pressure
Study 34333030 — Predictive Biomarker (PRD): RBM20 mRNA
Genes: RBM20
Study 33171431 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33478571 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 35072287 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 34962159 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36134465 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 616774622 — Surrogate Endpoint (SUR): Blood pressure
Study 33675475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33675475 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34706819 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34706819 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34775965 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 35430584 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 35430584 — Surrogate Endpoint (SUR): Serum testosterone
Study 32842974 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 35282662 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35282662 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32833484 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 32220069 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 35544369 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33161773 — Surrogate Endpoint (SUR): Blood pressure
Study 33586254 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 33586254 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 33456366 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 32144735 — Surrogate Endpoint (SUR): Pathological complete response
Study 35651610 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 35651610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35651610 — Safety Biomarker (SAF): IL-6 and IL-10
Study 32654663 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33885235 — Safety Biomarker (SAF): Reactive oxygen species
Study 33885235 — Surrogate Endpoint (SUR): Sperm parameters
Study 33885235 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 33840085 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 33840085 — Surrogate Endpoint (SUR): Blood pressure
Study 35222267 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 34235780 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34371381 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33398627 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 35147719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36172955 — Surrogate Endpoint (SUR): Blood pressure
Study 32146259 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 36279690 — Safety Biomarker (SAF): Hyaluronic acid
Study 35871944 — Surrogate Endpoint (SUR): Blood pressure
Study 32107188 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33352495 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33352495 — Surrogate Endpoint (SUR): Blood pressure
Study 32448782 — Surrogate Endpoint (SUR): Complete renal response
Study 32057627 — Surrogate Endpoint (SUR): Blood pressure
Study 33191181 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36238481 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 36238481 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 33232476 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 33232476 — Predictive Biomarker (PRD): IRAK1 mRNA
Genes: IRAK1; IRAK
Study 34821105 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34821105 — Surrogate Endpoint (SUR): Serum testosterone
Study 33115783 — Predictive Biomarker (PRD): FOSL1 mRNA
Genes: FOSL1; FRA1
Study 33115783 — Predictive Biomarker (PRD); Safety Biomarker (SAF): WNT11 mRNA
Genes: WNT11
Study 33115783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33090083 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 36384662 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 35019120 — Surrogate Endpoint (SUR): Serum potassium
Study 33321462 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34090987 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34090987 — Surrogate Endpoint (SUR): Blood pressure
Study 32948369 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 36268462 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34842573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33609741 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 32063531 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32894044 — Surrogate Endpoint (SUR): Blood pressure
Study 33592868 — Safety Biomarker (SAF): Hyaluronic acid
Study 36306168 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 33680312 — Predictive Biomarker (PRD): CLC mRNA
Genes: CLC; LGALS10; LGALS10A
Study 34840503 — Surrogate Endpoint (SUR): Blood pressure
Study 32312261 — Surrogate Endpoint (SUR): Blood pressure
Study 32581409 — Surrogate Endpoint (SUR): Blood pressure
Study 35790787 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33895559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35260450 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34735908 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35149326 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 34396784 — Predictive Biomarker (PRD): PLIN5 mRNA
Genes: PLIN5; LSDP5; OXPAT; PAT-1
Study 35689881 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 34497027 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34497027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34953185 — Surrogate Endpoint (SUR): Bone mineral density
Study 35960116 — Surrogate Endpoint (SUR): Blood pressure
Study 35411939 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 36224521 — Safety Biomarker (SAF): Connecting peptide
Genes: AHSG; FETUA; PRO2743
Study 33161159 — Predictive Biomarker (PRD): GRHL3 mRNA
Genes: GRHL3; SOM; TFCP2L4
Study 33685044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33685044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33685044 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32772509 — Surrogate Endpoint (SUR): Blood pressure
Study 36445624 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 36231251 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34693504 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34461991 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34016346 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34016346 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 34016346 — Surrogate Endpoint (SUR): Blood pressure
Study 33600915 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 33600915 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study 36217626 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32835417 — Surrogate Endpoint (SUR): Bone mineral density
Study 35654577 — Surrogate Endpoint (SUR): Bone mineral density
Study 34282831 — Safety Biomarker (SAF): Hyaluronic acid