TrialPanorama/TrialPanorama-database huggingface dataset:
Study 34363816 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 36162522 — Surrogate Endpoint (SUR): Blood pressure
Study 34116249 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34116249 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 89120227 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 33591006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34840031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34840031 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34929690 — Surrogate Endpoint (SUR): Blood pressure
Study 34459398 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 34459398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34459398 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 35830313 — Predictive Biomarker (PRD): VSIR mRNA
Genes: VSIR; C10orf54; SISP1; VISTA; PP2135; UNQ730/PRO1412
Study 36163989 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 36163989 — Predictive Biomarker (PRD): IRAK1 mRNA
Genes: IRAK1; IRAK
Study 36163989 — Predictive Biomarker (PRD): ACVR1 mRNA
Genes: ACVR1; ACVRLK2
Study 36163989 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 32073956 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 33430808 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33430808 — Predictive Biomarker (PRD): Hormone receptor
Study 33430808 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 35084038 — Surrogate Endpoint (SUR): Blood pressure
Study 32115032 — Predictive Biomarker (PRD): MYF5 mRNA
Genes: MYF5; BHLHC2
Study 32115032 — Predictive Biomarker (PRD): FBXO9 mRNA
Genes: FBXO9; FBX9; VCIA1
Study 32115032 — Predictive Biomarker (PRD): FBXO22 mRNA
Genes: FBXO22; FBX22
Study 32115032 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FBXO32 mRNA
Genes: FBXO32
Study 34925697 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 34801470 — Surrogate Endpoint (SUR): Bone mineral density
Study 33762414 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 35562373 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 33028675 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 33028675 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 33028675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35157829 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 35157829 — Predictive Biomarker (PRD): MTAP mRNA
Genes: MTAP; MSAP
Study 35157829 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study 35157829 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 34235415 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 34235415 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 33081762 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 35267027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35257062 — Surrogate Endpoint (SUR): Urinary oxalate
Study 32186246 — Surrogate Endpoint (SUR): Blood pressure
Study 32186246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33249810 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 36364963 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33185243 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 34351816 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 34351816 — Predictive Biomarker (PRD): DPEP1 mRNA
Genes: DPEP1; MDP; RDP
Study 35556946 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 35556946 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 35556946 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 35556946 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32325490 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 35366320 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33581821 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 34678908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34678908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34678908 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 34678908 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34678908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36150707 — Surrogate Endpoint (SUR): Bone mineral density
Study 33373464 — Surrogate Endpoint (SUR): Bone mineral density
Study 36109791 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35751744 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 36219303 — Surrogate Endpoint (SUR): Blood pressure
Study 32147536 — Predictive Biomarker (PRD): SOX9 mRNA
Genes: SOX9
Study 33685686 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 33151986 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32325419 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32325419 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 33909194 — Surrogate Endpoint (SUR): Blood pressure
Study 33909194 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33947355 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 35322001 — Predictive Biomarker (PRD): Microsatellite instability
Study 33724168 — Predictive Biomarker (PRD): GDF9 mRNA
Genes: GDF9
Study 33724168 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 33724168 — Safety Biomarker (SAF): miR-214
Genes: MIR214
Study 33724168 — Monitoring Biomarker (MOI): miR-92a-3p
Study 33724168 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-125b
Study 33028418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33028418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33028418 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 33028418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35049164 — Surrogate Endpoint (SUR): Blood pressure
Study 35819441 — Surrogate Endpoint (SUR): Blood pressure
Study 35405099 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33914304 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 33914304 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36164048 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 32000630 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 32988385 — Predictive Biomarker (PRD): MECP2 mRNA
Genes: MECP2
Study 33583165 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 33842006 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 33612615 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33345876 — Surrogate Endpoint (SUR): Blood pressure
Study 33345876 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 33345876 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33617194 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 35660539 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study 35660539 — Surrogate Endpoint (SUR): Blood pressure
Study 32820838 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 36441220 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33826537 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 32340471 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 32562573 — Predictive Biomarker (PRD): PEAR1 mRNA
Genes: PEAR1; MEGF12
Study 33686753 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33686753 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33686753 — Predictive Biomarker (PRD): Hormone receptor
Study 33513313 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33513313 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 33513313 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33285037 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 34730989 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32056158 — Surrogate Endpoint (SUR): Blood pressure
Study 32055820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34653557 — Surrogate Endpoint (SUR): Blood pressure
Study 34649223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34649223 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35217796 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 35217796 — Safety Biomarker (SAF): BDNF
Study 35217796 — Surrogate Endpoint (SUR): Blood pressure
Study 32616248 — Surrogate Endpoint (SUR): Serum calcium
Study 32046764 — Surrogate Endpoint (SUR): Blood pressure
Study 32804580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32804580 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 32804580 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33380614 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36430967 — Surrogate Endpoint (SUR): Blood pressure
Study 32886189 — Surrogate Endpoint (SUR): Bone mineral density
Study 36201131 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32513182 — Surrogate Endpoint (SUR): Blood pressure
Study 33187676 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 33225646 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 32313142 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 32313142 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32313142 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32066302 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 32376984 — Surrogate Endpoint (SUR): Blood pressure
Study 35092544 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 35092544 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 33608007 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32326621 — Surrogate Endpoint (SUR): Bone mineral density
Study 34814867 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study 32054543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32241780 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 35084022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35084022 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35917660 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 35917660 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 35227242 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 32073662 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 36493840 — Surrogate Endpoint (SUR): Blood pressure
Study 33154570 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 33785481 — Safety Biomarker (SAF): Reactive oxygen species
Study 32497023 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 33901017 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33901017 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 34410410 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 32101259 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32101259 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32101259 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34174326 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34174326 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 34048027 — Predictive Biomarker (PRD): LY75 mRNA
Genes: LY75; CD205; CLEC13B
Study 34048027 — Predictive Biomarker (PRD): GPR160 mRNA
Genes: GPR160; GPCR150
Study 35303958 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32009195 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 35418065 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32145827 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35473589 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 34369696 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34914334 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 36114901 — Surrogate Endpoint (SUR): Bone mineral density
Study 33917770 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33917770 — Surrogate Endpoint (SUR): Blood pressure
Study 34081966 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 32278676 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 32278676 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 32278676 — Predictive Biomarker (PRD): Microsatellite instability
Study 35344464 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 36056417 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34965953 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 34965953 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 36058418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32954593 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34531736 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34531736 — Safety Biomarker (SAF): BDNF
Study 34060903 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 34887285 — Surrogate Endpoint (SUR): Serum calcium
Study 34887285 — Surrogate Endpoint (SUR): Bone mineral density
Study 34327851 — Surrogate Endpoint (SUR): Blood pressure
Study 32472610 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 32472610 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32472610 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 35936372 — Surrogate Endpoint (SUR): Blood pressure
Study 36450422 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 36450422 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 33246495 — Surrogate Endpoint (SUR): Blood pressure
Study 36433716 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32304881 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32304881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32304881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32304881 — Safety Biomarker (SAF): BDNF
Study 32304881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32896775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33933738 — Surrogate Endpoint (SUR): Serum calcium
Study 33933738 — Surrogate Endpoint (SUR): Bone mineral density
Study 32737900 — Surrogate Endpoint (SUR): Platelet count response
Study 32891527 — Surrogate Endpoint (SUR): Blood pressure
Study 32522420 — Safety Biomarker (SAF): Hyaluronic acid
Study 34015342 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35526835 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33878341 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 35262490 — Surrogate Endpoint (SUR): Blood pressure
Study 34120122 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 35279331 — Surrogate Endpoint (SUR): Blood pressure
Study 32070388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32070388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34187535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32107452 — Surrogate Endpoint (SUR): Blood pressure
Study 33439727 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35543372 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33091614 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33091614 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 32808025 — Surrogate Endpoint (SUR): Blood pressure
Study 35039258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32112365 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33604801 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 33707061 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32541326 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 34439165 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34439165 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32893717 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35330577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35330577 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35330577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33283550 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 32311110 — Surrogate Endpoint (SUR): Serum creatinine
Study 32311110 — Surrogate Endpoint (SUR): Blood pressure
Study 33155105 — Surrogate Endpoint (SUR): Serum creatinine
Study 35367144 — Surrogate Endpoint (SUR): Blood pressure
Study 34130895 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34130895 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 34130895 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 33349849 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33299555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33299555 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 34729992 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 36271420 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 33914068 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34310714 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34310714 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34310714 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 34120651 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33251988 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32101630 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 33181142 — Predictive Biomarker (PRD): KRT1 mRNA
Genes: KRT1; KRTA
Study 33181142 — Predictive Biomarker (PRD): GRHL2 mRNA
Genes: GRHL2; BOM; TFCP2L3
Study 33181142 — Predictive Biomarker (PRD): SPRR4 mRNA
Genes: SPRR4
Study 34826341 — Surrogate Endpoint (SUR): Blood pressure
Study 35816815 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 35816815 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32833136 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35110416 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35110416 — Predictive Biomarker (PRD): CNT3 mRNA
Genes: SLC28A3; CNT3
Study 33794441 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 37078430 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 37078430 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 33879902 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 33879902 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4