TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33166718 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34433598 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 32097999 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 33762655 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36426809 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 33723346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33723346 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 34379025 — Surrogate Endpoint (SUR): Blood pressure
Study 35098554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33388204 — Surrogate Endpoint (SUR): Blood pressure
Study 35983809 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 36107466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35856224 — Surrogate Endpoint (SUR): Blood pressure
Study 33024552 — Predictive Biomarker (PRD): Liver iron
Study 33686922 — Surrogate Endpoint (SUR): Blood pressure
Study 33121984 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 32660517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32876469 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 32876469 — Surrogate Endpoint (SUR): Blood pressure
Study 33309467 — Predictive Biomarker (PRD): ASPM mRNA
Genes: ASPM; MCPH5
Study 32600481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33720478 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33683919 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 33371083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33371083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36214139 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 33867499 — Surrogate Endpoint (SUR): Bone mineral density
Study 35293068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35293068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33346477 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33346477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33346477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32754966 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 33999179 — Monitoring Biomarker (MOI): HBV DNA
Study 32644110 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 32651467 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 32651467 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32621898 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study 35895381 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 34892404 — Surrogate Endpoint (SUR): Blood pressure
Study 33982267 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 33982267 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 33982267 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 35332558 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 35332558 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 33735712 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35748451 — Surrogate Endpoint (SUR): Bacterial count
Study 32788052 — Safety Biomarker (SAF): Reactive oxygen species
Study 32334551 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36124078 — Surrogate Endpoint (SUR): Blood pressure
Study 34153248 — Surrogate Endpoint (SUR): Blood pressure
Study 33891194 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33870433 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 35483979 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35483979 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33564016 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 33564016 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 35105570 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 35105570 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35105570 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35105570 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35105570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35105570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 93092255 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 33559428 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 33559428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32449919 — Surrogate Endpoint (SUR): Blood pressure
Study 33559851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33559851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36457343 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36316075 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 34200027 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33741039 — Predictive Biomarker (PRD): MBTPS1 mRNA
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 32926803 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 36284289 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36284289 — Safety Biomarker (SAF): IL-6 and IL-10
Study 32542307 — Surrogate Endpoint (SUR): Blood pressure
Study 34348654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34348654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34348654 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33908295 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 36281472 — Predictive Biomarker (PRD): CCT3 mRNA
Genes: CCT3; CCTG; TRIC5
Study 33104519 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 33104519 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33104519 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 32372215 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 32372215 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-210
Genes: MIR210
Study 34172722 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 34941114 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33970363 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 34762528 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 34762528 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 33073935 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32726499 — Surrogate Endpoint (SUR): Blood pressure
Study 34962562 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 34962562 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 33410387 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 34950442 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33753147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33789011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36131324 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 33012059 — Predictive Biomarker (PRD): ITK mRNA
Genes: ITK; EMT; LYK
Study 34002565 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34089936 — Surrogate Endpoint (SUR): Serum calcium
Study 33515281 — Surrogate Endpoint (SUR): Urinary oxalate
Study 36052772 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36052772 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 35568683 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 32205331 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 32921665 — Safety Biomarker (SAF): Reactive oxygen species
Study 32277105 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32277105 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 35917647 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35917647 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 34197452 — Surrogate Endpoint (SUR): Blood pressure
Study 33136059 — Surrogate Endpoint (SUR): Blood pressure
Study 32093557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 616703485 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 36058007 — Surrogate Endpoint (SUR): Blood pressure
Study 33764282 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33764282 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 33764282 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 33764282 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 33764282 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study 33764282 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 33764282 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 33764282 — Predictive Biomarker (PRD): ITGAM mRNA
Genes: ITGAM; CD11B; CR3A
Study 33764282 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 33764282 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 33764282 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 33142495 — Surrogate Endpoint (SUR): Bone mineral density
Study 32956446 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32086949 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 34565172 — Surrogate Endpoint (SUR): Blood pressure
Study 32409493 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 32409493 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 33509132 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 36269141 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36269141 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 36269141 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36269141 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 36269141 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35349576 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 34912206 — Predictive Biomarker (PRD): ASPSCR1 mRNA
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 34912206 — Predictive Biomarker (PRD): TPSG1 mRNA
Genes: TPSG1; PRSS31; TMT
Study 32034028 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32034028 — Surrogate Endpoint (SUR): Blood pressure
Study 35250307 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 34610600 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32343960 — Monitoring Biomarker (MOI): HBV DNA
Study 36199780 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34393856 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33069120 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32311398 — Predictive Biomarker (PRD): TYK2 mRNA
Genes: TYK2
Study 32311398 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 34626060 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 33724534 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 32900329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35657627 — Surrogate Endpoint (SUR): Serum creatinine
Study 35657627 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 34160182 — Surrogate Endpoint (SUR): Blood pressure
Study 35848575 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32950416 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 34263700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36082667 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 35372380 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study 33203141 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 33203141 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 33203141 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33726834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33986049 — Surrogate Endpoint (SUR): Blood pressure
Study 32420695 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 36449571 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 35285853 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33300394 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33600354 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 36271849 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 36271849 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 35175284 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35175284 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35175284 — Predictive Biomarker (PRD): Hormone receptor
Study 33147353 — Surrogate Endpoint (SUR): Blood pressure
Study 33253391 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 32528467 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32528467 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 36240389 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 32590453 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33004536 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35742327 — Surrogate Endpoint (SUR): Blood pressure
Study 34801998 — Surrogate Endpoint (SUR): Blood pressure
Study 35749350 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 33935121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33303222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33303222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33303222 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 33303222 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 33094919 — Surrogate Endpoint (SUR): Pathological complete response
Study 32328662 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 33787831 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35575587 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35575587 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 35575587 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35575587 — Predictive Biomarker (PRD): Hormone receptor
Study 33038506 — Surrogate Endpoint (SUR): Blood pressure
Study 33091173 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32468652 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34406395 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 34406395 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 35279655 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34719355 — Surrogate Endpoint (SUR): Blood pressure
Study 36318635 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 33231489 — Predictive Biomarker (PRD): MZB1 mRNA
Genes: MZB1; MEDA7; PACAP; HSPC190
Study 34563992 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 32974907 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 32974907 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 35810307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35810307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33342939 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 33342939 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33342939 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33853806 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33811457 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 35297709 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34043272 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34148205 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32424430 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 34772330 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33635263 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 616115972 — Surrogate Endpoint (SUR): Bone mineral density
Study 33795324 — Surrogate Endpoint (SUR): Blood pressure
Study 35763326 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 33781053 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33781053 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 32220917 — Surrogate Endpoint (SUR): Blood pressure
Study 34597298 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 615918822 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35108031 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32330315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32330315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32310158 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32310158 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 36332136 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32825324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35486478 — Surrogate Endpoint (SUR): Blood pressure
Study 36463178 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36357840 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34708716 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32195370 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 34477026 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 34477026 — Predictive Biomarker (PRD): HSP90B1 mRNA
Genes: HSP90B1; GRP94; TRA1
Study 34477026 — Predictive Biomarker (PRD): EIF2AK3 mRNA
Genes: EIF2AK3; PEK; PERK
Study 34477026 — Predictive Biomarker (PRD): XBP1 mRNA
Genes: XBP1; TREB5; XBP2
Study 32705392 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35481707 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 35481707 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 34293624 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 34293624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34954864 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 34954864 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34843870 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC