TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35727053 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35727053 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 35727053 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 35727053 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 35727053 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 35727053 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33497870 — Safety Biomarker (SAF): IL-6 and IL-10
Study 33410589 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 33410589 — Surrogate Endpoint (SUR): Blood pressure
Study 34424307 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32828115 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 34011413 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32764090 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 35765086 — Surrogate Endpoint (SUR): Blood pressure
Study 33721611 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33351540 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35229613 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 35229613 — Surrogate Endpoint (SUR): Blood pressure
Study 33773170 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36054089 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 36054089 — Safety Biomarker (SAF): Reactive oxygen species
Study 33210285 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 33198235 — Safety Biomarker (SAF): Bacteroidetes phylum
Study 33121714 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34876412 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 32219775 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 34392146 — Safety Biomarker (SAF): Reactive oxygen species
Study 34392146 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 36224664 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 33899649 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 35158205 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33693703 — Surrogate Endpoint (SUR): Bone mineral density
Study 33487271 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33487271 — Surrogate Endpoint (SUR): Blood pressure
Study 34258785 — Predictive Biomarker (PRD): JMJD6 mRNA
Genes: JMJD6; KIAA0585; PSR; PTDSR
Study 32008434 — Surrogate Endpoint (SUR): Blood pressure
Study 35429246 — Predictive Biomarker (PRD): PIGR mRNA
Genes: PIGR
Study 35348351 — Predictive Biomarker (PRD): CCRL2 mRNA
Genes: CCRL2; CCR11; CCR6; CKRX; CRAM; HCR
Study 35348351 — Predictive Biomarker (PRD): ACKR2 mRNA
Genes: ACKR2; CCBP2; CCR10; CMKBR9; D6
Study 33807285 — Surrogate Endpoint (SUR): Blood pressure
Study 34235853 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 35605678 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 35605678 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35766272 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32816872 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 32816872 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 33878855 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 35211189 — Surrogate Endpoint (SUR): Serum creatinine
Study 35211189 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 33136654 — Surrogate Endpoint (SUR): Blood pressure
Study 36167555 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33112655 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33112655 — Safety Biomarker (SAF): BDNF
Study 34265388 — Safety Biomarker (SAF): Hyaluronic acid
Study 32814506 — Predictive Biomarker (PRD): SLC2A2 mRNA
Genes: SLC2A2; GLUT2
Study 35502897 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study 35502897 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 35255811 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 616655105 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 33587369 — Safety Biomarker (SAF): Hyaluronic acid
Study 36054131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36054131 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 33211921 — Surrogate Endpoint (SUR): Bone mineral density
Study 35902887 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35902887 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32879333 — Predictive Biomarker (PRD): MDK mRNA
Genes: MDK; MK1; NEGF2
Study 33619550 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33619550 — Predictive Biomarker (PRD): Hormone receptor
Study 32199656 — Surrogate Endpoint (SUR): Blood pressure
Study 32707579 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 32707579 — Predictive Biomarker (PRD): TDO2 mRNA
Genes: TDO2; TDO
Study 33066081 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 35112378 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 33012216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35889835 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35889835 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32000141 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32000141 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32790496 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35027932 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 35027932 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32421350 — Surrogate Endpoint (SUR): Blood pressure
Study 35748074 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 35748074 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 33307785 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35251573 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33930706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33459181 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 33459181 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 33459181 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 34230503 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34230503 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32393387 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36184252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33284480 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 33565706 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 33565706 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 32171721 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 32171721 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 34973831 — Surrogate Endpoint (SUR): Blood pressure
Study 32690519 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 36254015 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33844014 — Surrogate Endpoint (SUR): Blood pressure
Study 33028084 — Safety Biomarker (SAF): Platelet to lymphocyte
Study 33041039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35302412 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 34607865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34607865 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34607865 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32384578 — Surrogate Endpoint (SUR): Blood pressure
Study 33315763 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 33315763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35730613 — Surrogate Endpoint (SUR): Blood pressure
Study 33272365 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33272365 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35373585 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 33900918 — Predictive Biomarker (PRD): SYNM mRNA
Genes: SYNM; DMN; KIAA0353; SYN
Study 34938292 — Surrogate Endpoint (SUR): Pathological complete response
Study 36361437 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 32949918 — Surrogate Endpoint (SUR): Blood pressure
Study 32949918 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 35818187 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study 35818187 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 34247463 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32533085 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35447566 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 33565206 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35670262 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 35670262 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 36450541 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36450541 — Surrogate Endpoint (SUR): Blood pressure
Study 34539392 — Surrogate Endpoint (SUR): Serum uric acid
Study 34601163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34601163 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34651612 — Surrogate Endpoint (SUR): Blood pressure
Study 32027918 — Surrogate Endpoint (SUR): Blood pressure
Study 36228963 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 36228963 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 36228963 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36228963 — Predictive Biomarker (PRD): Hormone receptor
Study 32545655 — Predictive Biomarker (PRD): CYBA mRNA
Genes: CYBA
Study 32545655 — Safety Biomarker (SAF): Reactive oxygen species
Study 32545655 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33341707 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36072931 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34579068 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36435732 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 32931044 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 33198533 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33032837 — Surrogate Endpoint (SUR): Blood pressure
Study 33226186 — Surrogate Endpoint (SUR): Blood pressure
Study 35545446 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33010116 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 32810748 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32810748 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 32810748 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 32810748 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 32810748 — Predictive Biomarker (PRD): SMAD4 mRNA
Genes: SMAD4; DPC4; MADH4
Study 32810748 — Predictive Biomarker (PRD): Microsatellite instability
Study 35543701 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 35543701 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 35543701 — Predictive Biomarker (PRD): LILRB5 mRNA
Genes: LILRB5; LIR8
Study 32299241 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 32299241 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 32299241 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35331961 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33551021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33551021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34166834 — Surrogate Endpoint (SUR): Serum creatinine
Study 36262803 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34119409 — Surrogate Endpoint (SUR): Serum sodium
Study 33498165 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33826754 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 35354006 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 35397249 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 34195582 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 33982406 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33776997 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33776997 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34158524 — Surrogate Endpoint (SUR): Blood pressure
Study 616388376 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34267156 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 33860721 — Predictive Biomarker (PRD): FER mRNA
Genes: FER; TYK3
Study 32506733 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 32506733 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 32506733 — Safety Biomarker (SAF): Reactive oxygen species
Study 35579016 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 33475138 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32227157 — Surrogate Endpoint (SUR): Blood pressure
Study 32428718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32428718 — Safety Biomarker (SAF): Interleukin 1
Study 32428718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33662047 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33662047 — Safety Biomarker (SAF): BDNF
Study 32836055 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 32836055 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 35565715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 34453097 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35235092 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35235092 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 35235092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 616168805 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 616168805 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 616168805 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32407272 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 32407272 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 32407272 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 32407272 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 32407272 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 35315344 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 34323977 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33008345 — Surrogate Endpoint (SUR): Blood pressure
Study 35797794 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 35797794 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33687052 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 33340279 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 35805787 — Predictive Biomarker (PRD): HSPA1A mRNA
Genes: HSPA1A; HSP72; HSPA1; HSX70
Study 35805787 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 35805787 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35805787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33330899 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 33330899 — Surrogate Endpoint (SUR): Blood pressure
Study 33814447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33814447 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 33814447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33814447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 616118121 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 616118121 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 36361237 — Surrogate Endpoint (SUR): Blood pressure
Study 34309927 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 34309927 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 32185692 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 35345661 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 35345661 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35345661 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 35345661 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35576438 — Surrogate Endpoint (SUR): Serum creatinine
Study 33287911 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 37563249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32348832 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 32348832 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 32362175 — Surrogate Endpoint (SUR): Blood pressure
Study 33928209 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 33928209 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 32990618 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34967191 — Surrogate Endpoint (SUR): Blood pressure
Study 33849683 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 33849683 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 35689521 — Safety Biomarker (SAF): Hyaluronic acid
Study 33387550 — Surrogate Endpoint (SUR): Blood pressure
Study 33448402 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 33448402 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 33448402 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32467299 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 33793018 — Surrogate Endpoint (SUR): Blood pressure
Study 35028756 — Surrogate Endpoint (SUR): Blood pressure
Study 35750246 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 34602729 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 34602729 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32401600 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 32812836 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 37062416 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37062416 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37062416 — Predictive Biomarker (PRD): Hormone receptor
Study 33510477 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 32584396 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 34876393 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 33665812 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 33386953 — Surrogate Endpoint (SUR): Bone mineral density
Study 35811372 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35811372 — Predictive Biomarker (PRD): TNC mRNA
Genes: TNC; HXB
Study 35236568 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33543410 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32123242 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32123242 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32123242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34698499 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 34319427 — Surrogate Endpoint (SUR): Blood pressure
Study 35889747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35889747 — Monitoring Biomarker (MOI): HBV DNA
Study 35889747 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG