TrialPanorama/TrialPanorama-database huggingface dataset:
Study 37922692 — Predictive Biomarker (PRD): Microsatellite instability
Study 37922930 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37922989 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 37922989 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 37924084 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 37924154 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37926085 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 37926336 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 37928434 — Predictive Biomarker (PRD): MAP3K1 mRNA
Genes: MAP3K1; MAPKKK1; MEKK; MEKK1
Study 37928434 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-320b
Study 37928895 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37928922 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 37929602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37929602 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37929840 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 37929952 — Predictive Biomarker (PRD): NUCB1 mRNA
Genes: NUCB1; NUC
Study 37930156 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 37930781 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 37931445 — Predictive Biomarker (PRD): ASCL1 mRNA
Genes: ASCL1; ASH1; BHLHA46; HASH1
Study 37931445 — Predictive Biomarker (PRD): NEUROD1 mRNA
Genes: NEUROD1; BHLHA3; NEUROD
Study 37931445 — Predictive Biomarker (PRD): POU2F3 mRNA
Genes: POU2F3; OTF11; PLA1
Study 37931480 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 37931480 — Safety Biomarker (SAF): BDNF
Study 37931481 — Surrogate Endpoint (SUR): Blood pressure
Study 37931629 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 37932009 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 37932258 — Predictive Biomarker (PRD): AOC3 mRNA
Genes: AOC3; VAP1
Study 37932443 — Predictive Biomarker (PRD): SLC35A2 mRNA
Genes: SLC35A2; UGALT; UGT; UGTL
Study 37932648 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 37932650 — Surrogate Endpoint (SUR): Blood pressure
Study 37932961 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37932961 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 37933882 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 37934000 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 37934000 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 37934000 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 37934948 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 37935477 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 37935564 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 37935564 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 37935631 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37935631 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 37935631 — Predictive Biomarker (PRD): Hormone receptor
Study 37935839 — Surrogate Endpoint (SUR): Blood pressure
Study 37935839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37935977 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 37936126 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 37936126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37936126 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37936126 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 37936126 — Predictive Biomarker (PRD): DCN mRNA
Genes: DCN; SLRR1B
Study 37936126 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): GZMB mRNA
Genes: GZMB; CGL1; CSPB; CTLA1; GRB
Study 37936126 — Predictive Biomarker (PRD): GZMH mRNA
Genes: GZMH; CGL2; CTSGL2
Study 37936126 — Predictive Biomarker (PRD): MMP7 mRNA
Genes: MMP7; MPSL1; PUMP1
Study 37936687 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 37936687 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 37936699 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37936699 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 37937645 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 37937645 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 37937645 — Monitoring Biomarker (MOI): Angiopoietin 1 receptor
Genes: TEK; TIE2; VMCM; VMCM1
Study 37937763 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37938055 — Surrogate Endpoint (SUR): Blood pressure
Study 37938055 — Surrogate Endpoint (SUR): Serum creatinine
Study 37938055 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 37938495 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37938495 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 37938561 — Predictive Biomarker (PRD): MCTS1 mRNA
Genes: MCTS1; MCT1
Study 37938599 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 37938917 — Surrogate Endpoint (SUR): Blood pressure
Study 37939122 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 37939124 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 37939124 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 37939133 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 37939259 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study 37939259 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 37939264 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 37939262 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 37939397 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 37939397 — Predictive Biomarker (PRD): PEBP1 mRNA
Genes: PEBP1; PBP; PEBP
Study 37939397 — Predictive Biomarker (PRD): SFTPA2 mRNA
Genes: SFTPA2; COLEC5; PSAP; SFTP1; SFTPA; SFTPA2B
Study 37939397 — Predictive Biomarker (PRD): POF1B mRNA
Genes: POF1B
Study 37939397 — Predictive Biomarker (PRD): EPPK1 mRNA
Genes: EPPK1; EPIPL
Study 37939397 — Predictive Biomarker (PRD): PSMA4 mRNA
Genes: PSMA4; HC9; PSC9
Study 37939397 — Predictive Biomarker (PRD): CFL1 mRNA
Genes: CFL1; CFL
Study 37939628 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 37940151 — Safety Biomarker (SAF): miR-30c
Study 37940357 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 37940377 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37940446 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 37940671 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 37940671 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 37940671 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 37940936 — Surrogate Endpoint (SUR): Blood pressure
Study 37941012 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 37941050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37941113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37941823 — Surrogate Endpoint (SUR): Blood pressure
Study 37941888 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 37942277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37942314 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 37942314 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37942328 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 37942666 — Surrogate Endpoint (SUR): Probing pocket depth
Study 37942793 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37943221 — Surrogate Endpoint (SUR): Serum potassium
Study 37943223 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37943225 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 37943300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37943335 — Safety Biomarker (SAF): Reactive oxygen species
Study 37943335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37943335 — Surrogate Endpoint (SUR): Blood pressure
Study 37943350 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 37944074 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 37944528 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 37944528 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 37944528 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 37944528 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 37944586 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 37945063 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 37945284 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 37945311 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 37945441 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 37945748 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 37945748 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 37945755 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 37945755 — Predictive Biomarker (PRD): IKZF3 mRNA
Genes: IKZF3; ZNFN1A3
Study 37946122 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 37946136 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study 37946256 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 37946262 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 37946291 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 37947096 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 37947157 — Predictive Biomarker (PRD): MYB mRNA
Genes: MYB
Study 37947157 — Predictive Biomarker (PRD): NFIB mRNA
Genes: NFIB
Study 37947190 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 37947315 — Safety Biomarker (SAF): Interleukin 1
Study 37947315 — Safety Biomarker (SAF): Reactive oxygen species
Study 37947366 — Surrogate Endpoint (SUR): Serum creatinine
Study 37947366 — Surrogate Endpoint (SUR): Complete renal response
Study 37948170 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37948612 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 37948612 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 37948612 — Predictive Biomarker (PRD): MMP7 mRNA
Genes: MMP7; MPSL1; PUMP1
Study 37948612 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 37948612 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 37948612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37948759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37948759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37948759 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 37949165 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 37949351 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 37949432 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 37949595 — Surrogate Endpoint (SUR): Forced vital capacity
Study 37949619 — Predictive Biomarker (PRD): NDC80 mRNA
Genes: NDC80; HEC; HEC1; KNTC2
Study 37949621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37949931 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 37950301 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 37950338 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37950338 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 37950390 — Predictive Biomarker (PRD): Cyclin-dependent kinase-like 5
Genes: CDKL5; STK9
Study 37950533 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 37950907 — Surrogate Endpoint (SUR): Blood pressure
Study 37950918 — Surrogate Endpoint (SUR): Blood pressure
Study 37950919 — Surrogate Endpoint (SUR): Blood pressure
Study 37951881 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 37952030 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 37952085 — Predictive Biomarker (PRD): GALC mRNA
Genes: GALC
Study 37952114 — Safety Biomarker (SAF): Reactive oxygen species
Study 37952170 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 37952231 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 37953503 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study 37953503 — Predictive Biomarker (PRD): ZSWIM7 mRNA
Genes: ZSWIM7; SWS1
Study 37953814 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 37954548 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 37954548 — Surrogate Endpoint (SUR): Blood pressure
Study 37954548 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37954898 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 37955615 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37955615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37955741 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study 37956738 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study 37956738 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 37956738 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 37956759 — Surrogate Endpoint (SUR): Blood pressure
Study 37957132 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 37957175 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 37957175 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 37957373 — Safety Biomarker (SAF): Interleukin 1
Study 37957378 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 37957378 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 37957879 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37958791 — Predictive Biomarker (PRD): IL7 mRNA
Genes: IL7
Study 37958791 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 37960239 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 37960985 — Predictive Biomarker (PRD): CRTC1 mRNA
Genes: CRTC1; KIAA0616; MECT1; TORC1; WAMTP1
Study 37961215 — Predictive Biomarker (PRD): IL13RA1 mRNA
Genes: IL13RA1; IL13R; IL13RA
Study 37961215 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 37962072 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37962072 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37962077 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 37962746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 37962746 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37962876 — Surrogate Endpoint (SUR): Probing pocket depth
Study 37963155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37963304 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 37963317 — Predictive Biomarker (PRD): Microsatellite instability
Study 37963385 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 37964083 — Surrogate Endpoint (SUR): Blood pressure
Study 37964221 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 37964259 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37964259 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 37964379 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 37964379 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 37965307 — Predictive Biomarker (PRD): DPYSL2 mRNA
Genes: DPYSL2; CRMP2; ULIP2
Study 37965307 — Predictive Biomarker (PRD): GZMA mRNA
Genes: GZMA; CTLA3; HFSP
Study 37965307 — Predictive Biomarker (PRD): SERPINB3 mRNA
Genes: SERPINB3; SCCA; SCCA1
Study 37965307 — Predictive Biomarker (PRD): RHCG mRNA
Genes: RHCG; C15orf6; CDRC2; PDRC2; RHGK
Study 37965307 — Predictive Biomarker (PRD): PTPRR mRNA
Genes: PTPRR; ECPTP; PTPRQ
Study 37965307 — Predictive Biomarker (PRD): STMN3 mRNA
Genes: STMN3; SCLIP
Study 37965307 — Predictive Biomarker (PRD): TMPRSS4 mRNA
Genes: TMPRSS4; TMPRSS3; UNQ776/PRO1570
Study 37965307 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 37965628 — Monitoring Biomarker (MOI): Cell-free DNA
Study 37966286 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 37966285 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37966676 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study 37967136 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study 37967136 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 37967148 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 37967350 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 37967641 — Surrogate Endpoint (SUR): Blood pressure
Study 37968003 — Surrogate Endpoint (SUR): Blood pressure
Study 37968125 — Surrogate Endpoint (SUR): Blood pressure
Study 37968194 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 37968455 — Surrogate Endpoint (SUR): Blood pressure
Study 37968668 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 37968696 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37968696 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 37968738 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 37971194 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 37971194 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study 37971194 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 37971194 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 37971361 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 37971361 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 37971361 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 37971361 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 37971361 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 37971361 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study 37971487 — Surrogate Endpoint (SUR): Blood pressure
Study 37971692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37971723 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 37971723 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 37971722 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 37972346 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 37972346 — Monitoring Biomarker (MOI): Circulating tumor HPV DNA
Study 37972659 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 37972659 — Predictive Biomarker (PRD): BICC1 mRNA
Genes: BICC1
Study 37972659 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 37972659 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 37972659 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 37972659 — Monitoring Biomarker (MOI): Cell-free DNA
Study 37972659 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 37973477 — Surrogate Endpoint (SUR): Bone mineral density
Study 37973901 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 37973901 — Predictive Biomarker (PRD): KMT2C mRNA
Genes: KMT2C; HALR; KIAA1506; MLL3
Study 37973901 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 37973901 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 37973901 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 37974084 — Surrogate Endpoint (SUR): Blood pressure
Study 37974184 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 37975434 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 37975597 — Predictive Biomarker (PRD): Liver iron
Study 37976072 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37976375 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 37976375 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 37976654 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 37977105 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37977105 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37977159 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 37977159 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 37977159 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 37977159 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 37977486 — Predictive Biomarker (PRD): GFM1 mRNA
Genes: GFM1; EFG; EFG1; GFM
Study 37977713 — Predictive Biomarker (PRD): MTM1 mRNA
Genes: MTM1; CG2
Study 37977865 — Surrogate Endpoint (SUR): Blood pressure