TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32252739 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 35370914 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 36279409 — Surrogate Endpoint (SUR): Blood pressure
Study 33128085 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 33128085 — Predictive Biomarker (PRD): FOXA1 mRNA
Genes: FOXA1; HNF3A; TCF3A
Study 33128085 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 33128085 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 35075216 — Safety Biomarker (SAF): Interleukin 1
Study 35075216 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32497586 — Surrogate Endpoint (SUR): Blood pressure
Study 35674861 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33765581 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 35796209 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33772443 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 35513977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34422049 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34422049 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 34422049 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 35160103 — Surrogate Endpoint (SUR): Blood pressure
Study 32338345 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 32338345 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 32338345 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32338345 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 32338345 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 35342036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33423824 — Surrogate Endpoint (SUR): Blood pressure
Study 32560705 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 36145177 — Predictive Biomarker (PRD); Safety Biomarker (SAF): BHMT mRNA
Genes: BHMT
Study 33568556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33568556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35379538 — Surrogate Endpoint (SUR): Blood pressure
Study 32553790 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 36206874 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 36443792 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 34160288 — Predictive Biomarker (PRD): ERFE mRNA
Genes: ERFE; C1QTNF15; CTRP15; FAM132B
Study 36242622 — Safety Biomarker (SAF): Hyaluronic acid
Study 35094123 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 35094123 — Surrogate Endpoint (SUR): Blood pressure
Study 32143877 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 34219267 — Surrogate Endpoint (SUR): Sperm parameters
Study 34219267 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 32115027 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 34418898 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study 32437507 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 35170493 — Safety Biomarker (SAF): Interleukin 1
Study 33846727 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32854869 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 34993933 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34993933 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 33764609 — Predictive Biomarker (PRD): SH2D2A mRNA
Genes: SH2D2A; SCAP; TSAD; VRAP
Study 35664355 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 35656881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34118980 — Surrogate Endpoint (SUR): Serum creatinine
Study 32423462 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34472497 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34380099 — Surrogate Endpoint (SUR): Blood pressure
Study 35693290 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32823594 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 32823594 — Predictive Biomarker (PRD): ADORA2A mRNA
Genes: ADORA2A; ADORA2
Study 32488672 — Surrogate Endpoint (SUR): Serum creatinine
Study 35543679 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 36364960 — Surrogate Endpoint (SUR): Blood pressure
Study 35183790 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 35183790 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34426106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34740861 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32273183 — Predictive Biomarker (PRD): Hormone receptor
Study 34045018 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34045018 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 34045018 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33356977 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34881512 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34437607 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 34937600 — Predictive Biomarker (PRD): PTBP2 mRNA
Genes: PTBP2; NPTB; PTB; PTBLP
Study 32875492 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32875492 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 32875492 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33789252 — Surrogate Endpoint (SUR): Blood pressure
Study 32326719 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 35022501 — Predictive Biomarker (PRD): IVNS1ABP mRNA
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 32445975 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 35179758 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33097026 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 33112511 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 36348476 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33992189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 33000618 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36047376 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 33663487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33532874 — Surrogate Endpoint (SUR): Blood pressure
Study 33550259 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 35914112 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33419461 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32035487 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 32035487 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32035487 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32035487 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32382922 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 32598997 — Surrogate Endpoint (SUR): Blood pressure
Study 35565903 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33491305 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 33491305 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 33491305 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 33491305 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 33491305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33814890 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33814890 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 34996409 — Surrogate Endpoint (SUR): Bone mineral density
Study 32267348 — Surrogate Endpoint (SUR): Serum creatinine
Study 32267348 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 32267348 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 32267348 — Surrogate Endpoint (SUR): Blood pressure
Study 32267348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33932873 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33885930 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 32049789 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32049789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32049789 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33561514 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 37941802 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32470515 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34405256 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 32813947 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 32813947 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32246106 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 32246106 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 34116394 — Surrogate Endpoint (SUR): Blood pressure
Study 34116394 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34116394 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35710247 — Surrogate Endpoint (SUR): Blood pressure
Study 35672161 — Predictive Biomarker (PRD): DPEP1 mRNA
Genes: DPEP1; MDP; RDP
Study 34284783 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34284783 — Surrogate Endpoint (SUR): Blood pressure
Study 32019599 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 32019599 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 32019599 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34165199 — Surrogate Endpoint (SUR): Blood pressure
Study 35010881 — Surrogate Endpoint (SUR): Blood pressure
Study 34237249 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 34109364 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33308259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36031952 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 34242246 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 34242246 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 35264075 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36450626 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 36450626 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 36450626 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34772434 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 34772434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 35902299 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35902299 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35766041 — Surrogate Endpoint (SUR): Blood pressure
Study 34584881 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 32514012 — Monitoring Biomarker (MOI): miR-29a
Genes: MIR29A
Study 34962679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33583347 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 36058253 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33915514 — Predictive Biomarker (PRD): WARS1 mRNA
Genes: WARS1; IFI53; WARS; WRS
Study 34888663 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 32909497 — Surrogate Endpoint (SUR): Blood pressure
Study 36429761 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34783882 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 34899426 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 34960005 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 32147880 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 36036731 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 33794182 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33891907 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33302991 — Safety Biomarker (SAF): Interleukin 1
Study 33302991 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35156255 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 35751657 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 35751657 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 33637368 — Surrogate Endpoint (SUR): Blood pressure
Study 32020185 — Predictive Biomarker (PRD): ISG15 mRNA
Genes: ISG15; G1P2; UCRP
Study 32020185 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 32020185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32020185 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 32020185 — Predictive Biomarker (PRD): IRF9 mRNA
Genes: IRF9; ISGF3G
Study 32020185 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 32020185 — Safety Biomarker (SAF): C-X-C motif chemokine 5
Genes: CXCL5; ENA78; SCYB5
Study 32020185 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32020185 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 32020185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34605384 — Surrogate Endpoint (SUR): Blood pressure
Study 32219719 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 33310502 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 33128677 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35107113 — Surrogate Endpoint (SUR): Blood pressure
Study 35179770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35321653 — Surrogate Endpoint (SUR): Blood pressure
Study 32326980 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 36069668 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 33749317 — Predictive Biomarker (PRD): SCGB1A1 mRNA
Genes: SCGB1A1; CC10; CCSP; UGB
Study 33749317 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34006898 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34006898 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 34006898 — Surrogate Endpoint (SUR): Blood pressure
Study 32059692 — Surrogate Endpoint (SUR): Blood pressure
Study 32059692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32059692 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32951084 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35091170 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34902089 — Surrogate Endpoint (SUR): Blood pressure
Study 34476568 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34476568 — Safety Biomarker (SAF): BDNF
Study 33884978 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 36052527 — Surrogate Endpoint (SUR): Blood pressure
Study 36522805 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 36522805 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 36522805 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 34409753 — Surrogate Endpoint (SUR): Blood pressure
Study 35030335 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33413636 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34120160 — Surrogate Endpoint (SUR): Blood pressure
Study 34227468 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 34227468 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32419245 — Predictive Biomarker (PRD): SNN mRNA
Genes: SNN
Study 33835842 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34214136 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32623650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32623650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33308471 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32554072 — Surrogate Endpoint (SUR): Blood pressure
Study 33734131 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34480861 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 34282598 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 34282598 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34371102 — Predictive Biomarker (PRD): PEG10 mRNA
Genes: PEG10; EDR; KIAA1051e; MAR2; MART2; MEF3L1; RGAG3
Study 35763041 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 35763041 — Predictive Biomarker (PRD): GPX3 mRNA
Genes: GPX3; GPXP
Study 35763041 — Predictive Biomarker (PRD): ACTR3 mRNA
Genes: ACTR3; ARP3
Study 35763041 — Predictive Biomarker (PRD): ARHGAP1 mRNA
Genes: ARHGAP1; CDC42GAP; RHOGAP1
Study 35763041 — Predictive Biomarker (PRD): VPS13A mRNA
Genes: VPS13A; CHAC; KIAA0986
Study 35763041 — Predictive Biomarker (PRD): KALRN mRNA
Genes: KALRN; DUET; DUO; HAPIP; TRAD
Study 33951448 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 32552731 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 33028396 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 33028396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35733213 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 33674988 — Predictive Biomarker (PRD): FBXO8 mRNA
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 32333877 — Surrogate Endpoint (SUR): Bone mineral density
Study 35187164 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32987917 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34438242 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 34438242 — Predictive Biomarker (PRD): TLE4 mRNA
Genes: TLE4; GRG4; KIAA1261
Study 32798050 — Predictive Biomarker (PRD): GDA mRNA
Genes: GDA; KIAA1258
Study 32798050 — Predictive Biomarker (PRD): GNL3 mRNA
Genes: GNL3; E2IG3; NS
Study 32243009 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32243009 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33207093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36318438 — Surrogate Endpoint (SUR): Blood pressure
Study 32672829 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 36027496 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study 36027496 — Surrogate Endpoint (SUR): Blood pressure
Study 33640203 — Pharmacodynamic Biomarker (PDY): Guanine nucleotide exchange factor C9orf72
Genes: C9orf72; DENND9; DENNL72
Study 33640203 — Predictive Biomarker (PRD): G2E3 mRNA
Genes: G2E3; KIAA1333
Study 33640203 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 33640203 — Predictive Biomarker (PRD): CLCN3 mRNA
Genes: CLCN3
Study 33640203 — Predictive Biomarker (PRD): GGNBP2 mRNA
Genes: GGNBP2; LCRG1; LZK1; ZNF403
Study 32387055 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35499570 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34531304 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 35351253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34380811 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 34774052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33302654 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33302654 — Surrogate Endpoint (SUR): Blood pressure
Study 36116480 — Predictive Biomarker (PRD): Hormone receptor