TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05929365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT05897515 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06060275 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study NCT05669768 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT06353061 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT06257290 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT06257290 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study NCT06257290 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study NCT06589596 — Predictive Biomarker (PRD): MTAP mRNA
Genes: MTAP; MSAP
Study NCT03997097 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT05011916 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT05011916 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT05315830 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04950881 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05323864 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study NCT00000962 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05436002 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05813327 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT04864743 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT05862324 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT04304755 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04304755 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04304755 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05087134 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT06324994 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT06046495 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05352386 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT05957757 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05518422 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT06773936 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT06773936 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT06420817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06420817 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06121557 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05029687 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04672356 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study NCT06036563 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT03362736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06555705 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06447025 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study NCT05976113 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study NCT05976113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT05976113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT04912141 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06195124 — Predictive Biomarker (PRD): RGL1 mRNA
Genes: RGL1; KIAA0959; RGL
Study NCT06242288 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT05845151 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05610462 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06127498 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05437341 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05437341 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT06514599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04912180 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05393362 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05433402 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT05433402 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study NCT04912622 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT05947669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06746753 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT06351592 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04802876 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06739668 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05627427 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT05627427 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study NCT04632095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06374459 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06374459 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06374459 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04684563 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT04684563 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05841550 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05841550 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT05807334 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT05807334 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04781647 — Monitoring Biomarker (MOI): HBV DNA
Study NCT06630234 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study NCT05581823 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05501769 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05392387 — Monitoring Biomarker (MOI): HBV DNA
Study NCT05739045 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05762536 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05762536 — Predictive Biomarker (PRD): ARSI mRNA
Genes: ARSI
Study NCT05828225 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05706987 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04762199 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study NCT04762199 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06245265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06176820 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05276843 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06384378 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04391777 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06199297 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05186584 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06151353 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06315764 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05615415 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT04446793 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05289713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05771584 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04942912 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT04999943 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT00338546 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06280690 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04635397 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study NCT05018702 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06351345 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT05921760 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT05232916 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05232916 — Predictive Biomarker (PRD): GP2 mRNA
Genes: GP2
Study NCT05232916 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05232916 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT05126732 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT05927064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04498754 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05543356 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06144944 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06144944 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04103554 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04820868 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05372679 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04418414 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04418414 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study NCT05459727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06377293 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT06377293 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06520176 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06520176 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05982106 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT05982106 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study NCT02385396 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT06265090 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06728982 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05959772 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study NCT05613894 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05128812 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06770439 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT02915406 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT06526702 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT06305416 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06305416 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06373913 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT05888870 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT06111807 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00002214 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04323748 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT04845932 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05819905 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05819905 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05819905 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05819905 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05819905 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study NCT05426005 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT05885464 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT05683977 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06645457 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05973084 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06148090 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT06148090 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05773131 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06364163 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT04925648 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04922424 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04922424 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04922424 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT05504213 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05504213 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05504213 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT05504213 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05504213 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06112613 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04898894 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT04037241 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT05646030 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT05853718 — Monitoring Biomarker (MOI): HBV DNA
Study NCT05745545 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05627141 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04878120 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study NCT00443222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06334991 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05801263 — Predictive Biomarker (PRD): CDO1 mRNA
Genes: CDO1
Study NCT05801263 — Predictive Biomarker (PRD): HOXA9 mRNA
Genes: HOXA9; HOX1G
Study NCT05801263 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05552781 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06605846 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06610643 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06612476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06612814 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06612814 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06612814 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06612060 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study NCT06612060 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT05151341 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT03348670 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study NCT03348670 — Predictive Biomarker (PRD): SULT2A1 mRNA
Genes: SULT2A1; HST; STD
Study NCT06677970 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05272423 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05539222 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05539222 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05539222 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06515327 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06738381 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05601713 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06053814 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06053814 — Surrogate Endpoint (SUR): Skeletal muscle dystrophin
Study NCT05874271 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT06774222 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04969835 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05689463 — Predictive Biomarker (PRD): COL17A1 mRNA
Genes: COL17A1; BP180; BPAG2
Study NCT06117020 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study NCT04736589 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04736589 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT05955625 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01096199 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT04987853 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05238961 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT05427383 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05911126 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study NCT06067867 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05847166 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04676009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05427123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06218914 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06218914 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study NCT05647811 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT06115902 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05392127 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05392127 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT05392127 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT05563545 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04565548 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05447793 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04456491 — Safety Biomarker (SAF): Arginase-1
Genes: ARG1
Study NCT05078203 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05078203 — Predictive Biomarker (PRD): CTSB mRNA
Genes: CTSB; CPSB
Study NCT05078203 — Safety Biomarker (SAF): BDNF
Study NCT05238948 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05536518 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04594005 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04594005 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study NCT04594005 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study NCT04594005 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT04594005 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study NCT06379750 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04904471 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04904471 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05438979 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study NCT06467175 — Predictive Biomarker (PRD): NOTCH2NLC mRNA
Genes: NOTCH2NLC
Study NCT05179746 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT06553456 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT05141097 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05653947 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT05988099 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05988099 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06014320 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT06293911 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06740045 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study NCT06738160 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06738160 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study NCT06738160 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05986981 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT06739564 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study NCT06739980 — Predictive Biomarker (PRD): ENPP1 mRNA
Genes: ENPP1; M6S1; NPPS; PC1; PDNP1
Study NCT06739655 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05680896 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05204147 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT06736613 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05886777 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05308290 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06008860 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04489589 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06424379 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study NCT05348889 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05388669 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05293288 — Surrogate Endpoint (SUR): Blood pressure