TrialPanorama/TrialPanorama-database huggingface dataset:
Study 37977903 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37977942 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 37978197 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37978284 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 37978492 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 37978492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37978492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37978951 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 37979048 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 37979133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37979594 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 37980367 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 37980367 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 37980875 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 37981049 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 37981049 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 37981090 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37981564 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 37981564 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 37981596 — Predictive Biomarker (PRD): TYK2 mRNA
Genes: TYK2
Study 37981665 — Monitoring Biomarker (MOI): Procalcitonin
Study 37981892 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 37981892 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 37982276 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37982276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37982388 — Surrogate Endpoint (SUR): Bone mineral density
Study 37982547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37982547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37982575 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 37982575 — Predictive Biomarker (PRD): Hormone receptor
Study 37982575 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 37982827 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 37982827 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 37982827 — Predictive Biomarker (PRD): GNAQ mRNA
Genes: GNAQ; GAQ
Study 37982827 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 37982827 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 37982827 — Predictive Biomarker (PRD): CCND2 mRNA
Genes: CCND2
Study 37982827 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37982966 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 37983082 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 37983823 — Surrogate Endpoint (SUR): Blood pressure
Study 37984453 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 37984741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37984741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37984741 — Surrogate Endpoint (SUR): Bone mineral density
Study 37984940 — Surrogate Endpoint (SUR): Blood pressure
Study 37984956 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37985359 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 37985386 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 37985817 — Predictive Biomarker (PRD): FABP5 mRNA
Genes: FABP5
Study 37985994 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 37986021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37986149 — Surrogate Endpoint (SUR): Blood pressure
Study 37986911 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 37986940 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 37986940 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37987186 — Predictive Biomarker (PRD): AKR1B10 mRNA
Genes: AKR1B10; AKR1B11
Study 37987186 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 37987893 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 37987893 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 37988294 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 37988449 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 37988449 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37988648 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37989943 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 37989943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37990162 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 37990163 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 37990223 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 37990224 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 37990670 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 37991122 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37991178 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 37991639 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37991778 — Predictive Biomarker (PRD): ARHGEF5 mRNA
Genes: ARHGEF5; TIM
Study 37991939 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37991939 — Predictive Biomarker (PRD): Hormone receptor
Study 37993062 — Predictive Biomarker (PRD): EVC mRNA
Genes: EVC
Study 37993168 — Predictive Biomarker (PRD): AFM mRNA
Genes: AFM; ALB2; ALBA
Study 37993199 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37993199 — Surrogate Endpoint (SUR): Blood pressure
Study 37993201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37993666 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 37993889 — Predictive Biomarker (PRD): CA3 mRNA
Genes: CA3
Study 37993961 — Predictive Biomarker (PRD): KCNK3 mRNA
Genes: KCNK3; TASK; TASK1
Study 37993961 — Surrogate Endpoint (SUR): Blood pressure
Study 37994400 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 37994400 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37994980 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 37995070 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37996787 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37996787 — Surrogate Endpoint (SUR): Blood pressure
Study 37997800 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37997800 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 37997800 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 37999656 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 37999854 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 38000815 — Surrogate Endpoint (SUR): Serum potassium
Study 38001310 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 38001469 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 38001469 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 38001474 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38001507 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 38004228 — Surrogate Endpoint (SUR): Blood pressure
Study 38006908 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 38006908 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 38006908 — Surrogate Endpoint (SUR): Blood pressure
Study 38007349 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38008001 — Predictive Biomarker (PRD): LAMA2 mRNA
Genes: LAMA2; LAMM
Study 38008001 — Predictive Biomarker (PRD): SELENON mRNA
Genes: SELENON; SELN; SEPN1
Study 38008001 — Predictive Biomarker (PRD): SRCIN1 mRNA
Genes: SRCIN1; KIAA1684; P140; SNIP
Study 38008001 — Surrogate Endpoint (SUR): Forced vital capacity
Study 38009200 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 38009241 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 38009310 — Surrogate Endpoint (SUR): Blood pressure
Study 38009662 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38009933 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 38009933 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 38009933 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 38009933 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study 38010260 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 38010260 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 38010394 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 38010394 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 38011131 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 38011704 — Surrogate Endpoint (SUR): Blood pressure
Study 38011922 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 38011968 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 38011968 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38012285 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 38012327 — Predictive Biomarker (PRD): KLRC2 mRNA
Genes: KLRC2; NKG2C
Study 38012327 — Surrogate Endpoint (SUR): Blood pressure
Study 38012534 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 38012534 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 38012534 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 38012534 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 38012795 — Safety Biomarker (SAF): DRD2
Study 38012835 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 38012835 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 38013523 — Surrogate Endpoint (SUR): Blood pressure
Study 38013594 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 38014146 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 38014479 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 38014676 — Surrogate Endpoint (SUR): Blood pressure
Study 38014691 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38014691 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 38014691 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 38015039 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 38015220 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38015467 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ERCC2
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 38015901 — Surrogate Endpoint (SUR): Blood pressure
Study 38016160 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38016322 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38016482 — Predictive Biomarker (PRD): KMT2D mRNA
Genes: KMT2D; ALR; MLL2; MLL4
Study 38016482 — Predictive Biomarker (PRD): Microsatellite instability
Study 38016718 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38016718 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38016718 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38017103 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 38017103 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 38017103 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 38017103 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 38017103 — Predictive Biomarker (PRD): U2AF1 mRNA
Genes: U2AF1; U2AF35; U2AFBP; FP793
Study 38017103 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 38017103 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 38017325 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 38017432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 38017482 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 38017482 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 38019014 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 38019014 — Predictive Biomarker (PRD): BCOR mRNA
Genes: BCOR; KIAA1575
Study 38019014 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 38019014 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 38019014 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 38019014 — Predictive Biomarker (PRD): LRP1B mRNA
Genes: LRP1B; LRPDIT
Study 38019014 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 38019014 — Predictive Biomarker (PRD): KMT2C mRNA
Genes: KMT2C; HALR; KIAA1506; MLL3
Study 38019014 — Predictive Biomarker (PRD): NFE2 mRNA
Genes: NFE2
Study 38019116 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38019116 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 38019287 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 38019356 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 38019356 — Predictive Biomarker (PRD): TRPC4 mRNA
Genes: TRPC4
Study 38019444 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38019512 — Surrogate Endpoint (SUR): Serum creatinine
Study 38020201 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 38020522 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 38020587 — Predictive Biomarker (PRD): 14-3-3 protein sigma
Genes: SFN; HME1
Study 38023564 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 38024244 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 38025217 — Surrogate Endpoint (SUR): Serum creatinine
Study 38025971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38025971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38026295 — Surrogate Endpoint (SUR): Blood pressure
Study 38026375 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 38027064 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 38027106 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 38027217 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 38027469 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study 38028143 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38028429 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 38029357 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 38029625 — Predictive Biomarker (PRD): CACNA1C mRNA
Genes: CACNA1C; CACH2; CACN2; CACNL1A1; CCHL1A1
Study 38029807 — Predictive Biomarker (PRD): TRAF6 mRNA
Genes: TRAF6; RNF85
Study 38029807 — Predictive Biomarker (PRD): MAP3K7 mRNA
Genes: MAP3K7; TAK1
Study 38030318 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 38030318 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 38030318 — Surrogate Endpoint (SUR): Blood pressure
Study 38030558 — Surrogate Endpoint (SUR): Bone mineral density
Study 38030971 — Surrogate Endpoint (SUR): Serum creatinine
Study 38030975 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 38031088 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 38031156 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38032247 — Surrogate Endpoint (SUR): Blood pressure
Study 38032582 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38032624 — Surrogate Endpoint (SUR): Blood pressure
Study 38032644 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38032644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 38033615 — Predictive Biomarker (PRD): GRIN1 mRNA
Genes: GRIN1; NMDAR1
Study 38034378 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38034378 — Surrogate Endpoint (SUR): Blood pressure
Study 38035176 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 38035363 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 38035725 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 38035747 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 38035747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 38035997 — Surrogate Endpoint (SUR): Blood pressure
Study 38036712 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 38036720 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 38036720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38036930 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 38037188 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 38037749 — Surrogate Endpoint (SUR): Blood pressure
Study 38037804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38037804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 38037804 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 38037839 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38037839 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38037839 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 38037839 — Predictive Biomarker (PRD): Hormone receptor
Study 38038339 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38039432 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study 38039432 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 38039511 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 38039831 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 38039831 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 38040274 — Surrogate Endpoint (SUR): Blood pressure
Study 38040277 — Surrogate Endpoint (SUR): Bone mineral density
Study 38040541 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 38040541 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 38041762 — Surrogate Endpoint (SUR): Blood pressure
Study 38041959 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 38041959 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 38042412 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 38042525 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 38043867 — Predictive Biomarker (PRD): HPN mRNA
Genes: HPN; TMPRSS1
Study 38043911 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 38043911 — Safety Biomarker (SAF): IL-6 and IL-10
Study 38043911 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38043911 — Safety Biomarker (SAF): BDNF
Study 38045238 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 38045238 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 38045238 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 38045238 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 38045238 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38045238 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 38045238 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 38045774 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 38046376 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 38046911 — Surrogate Endpoint (SUR): Blood pressure
Study 38046912 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 38048045 — Predictive Biomarker (PRD): SSTR2 mRNA
Genes: SSTR2
Study 38048133 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 38048147 — Surrogate Endpoint (SUR): Blood pressure