TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33794005 — Surrogate Endpoint (SUR): Bone mineral density
Study 34753844 — Surrogate Endpoint (SUR): Bacterial count
Study 32816561 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34626958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35363600 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36288835 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32408117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32408117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32408117 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32408117 — Safety Biomarker (SAF): IL-6 and IL-10
Study 32649638 — Surrogate Endpoint (SUR): Blood pressure
Study 32876858 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32789772 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33947618 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 34825728 — Surrogate Endpoint (SUR): Blood pressure
Study 32027620 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 32027620 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33538094 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35121493 — Predictive Biomarker (PRD): CXCL16 mRNA
Genes: CXCL16; SCYB16; SRPSOX; UNQ2759/PRO6714
Study 35121493 — Predictive Biomarker (PRD): CXCR6 mRNA
Genes: CXCR6; BONZO; STRL33; TYMSTR
Study 34450552 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34450552 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34450552 — Predictive Biomarker (PRD): Hormone receptor
Study 32357913 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 36050801 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 33899526 — Safety Biomarker (SAF): Hyaluronic acid
Study 35028992 — Surrogate Endpoint (SUR): Blood pressure
Study 32000711 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32781104 — Predictive Biomarker (PRD): MYB mRNA
Genes: MYB
Study 32781104 — Predictive Biomarker (PRD): NFIB mRNA
Genes: NFIB
Study 32781104 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32819979 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study 32819979 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 32819979 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32819979 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33228950 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32243644 — Surrogate Endpoint (SUR): Blood pressure
Study 33214244 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study 33677400 — Predictive Biomarker (PRD): Hormone receptor
Study 35766022 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35766022 — Safety Biomarker (SAF): Urinary total protein
Study 33811477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32277954 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 32277954 — Predictive Biomarker (PRD): miR-17
Genes: MIR17
Study 32277954 — Safety Biomarker (SAF): miR-18a
Genes: MIR18A
Study 36244398 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 32578279 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35881908 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35105604 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35105604 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 35458201 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 34864158 — Monitoring Biomarker (MOI): HBV DNA
Study 32867053 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 32867053 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33017836 — Surrogate Endpoint (SUR): Blood pressure
Study 34781421 — Surrogate Endpoint (SUR): Blood pressure
Study 32979188 — Predictive Biomarker (PRD): RNPEP mRNA
Genes: RNPEP; APB
Study 34992202 — Surrogate Endpoint (SUR): Blood pressure
Study 34992202 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34265211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34265211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34265211 — Safety Biomarker (SAF): IL-6 and IL-10
Study 33507266 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 36235651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32705831 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32705831 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35771216 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 34636309 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 34743533 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 36389295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34247026 — Predictive Biomarker (PRD): HRC mRNA
Genes: HRC; HCP
Study 34799110 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 35102732 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 35102732 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34105177 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 32975131 — Surrogate Endpoint (SUR): Blood pressure
Study 34844295 — Surrogate Endpoint (SUR): Blood pressure
Study 32186656 — Predictive Biomarker (PRD): DSG3 mRNA
Genes: DSG3; CDHF6
Study 32186656 — Predictive Biomarker (PRD): DSG1 mRNA
Genes: DSG1; CDHF4
Study 33357709 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33357709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33357709 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33357709 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33357709 — Safety Biomarker (SAF): Interleukin 1
Study 34525277 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32992943 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 34882176 — Predictive Biomarker (PRD): USH1G mRNA
Genes: USH1G; SANS
Study 34284348 — Surrogate Endpoint (SUR): Blood pressure
Study 34798038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33899093 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33683586 — Predictive Biomarker (PRD): RGR mRNA
Genes: RGR
Study 35802960 — Surrogate Endpoint (SUR): Blood pressure
Study 34358271 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 32548299 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32548299 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32548299 — Predictive Biomarker (PRD): Hormone receptor
Study 36735054 — Surrogate Endpoint (SUR): Bone mineral density
Study 33452957 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35096113 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35096113 — Predictive Biomarker (PRD): FBXO8 mRNA
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 35096113 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 34369681 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34369681 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35790450 — Surrogate Endpoint (SUR): Blood pressure
Study 33484775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34612663 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 35099597 — Surrogate Endpoint (SUR): Bone mineral density
Study 33314326 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33314326 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 34394889 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34394889 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34394889 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32997262 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 36090743 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 35777773 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34840669 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 35199841 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35199841 — Surrogate Endpoint (SUR): Blood pressure
Study 34214161 — Predictive Biomarker (PRD): BMP8A mRNA
Genes: BMP8A
Study 34214161 — Predictive Biomarker (PRD): STX18 mRNA
Genes: STX18; GIG9
Study 34214161 — Predictive Biomarker (PRD): ZNF365 mRNA
Genes: ZNF365; KIAA0844
Study 34214161 — Predictive Biomarker (PRD): CPT1A mRNA
Genes: CPT1A; CPT1
Study 34214161 — Predictive Biomarker (PRD): TRIM37 mRNA
Genes: TRIM37; KIAA0898; MUL; POB1
Study 34214161 — Predictive Biomarker (PRD): TXNIP mRNA
Genes: TXNIP; VDUP1
Study 34214161 — Predictive Biomarker (PRD): COMMD1 mRNA
Genes: COMMD1; C2orf5; MURR1
Study 34214161 — Predictive Biomarker (PRD): TMOD1 mRNA
Genes: TMOD1; D9S57E; TMOD
Study 34214161 — Predictive Biomarker (PRD): FHOD1 mRNA
Genes: FHOD1; FHOS; FHOS1
Study 36434739 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 33338583 — Surrogate Endpoint (SUR): Blood pressure
Study 32638144 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 35303017 — Surrogate Endpoint (SUR): Blood pressure
Study 35760497 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32270891 — Surrogate Endpoint (SUR): Bone mineral density
Study 35484697 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 33277370 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35512068 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34023888 — Surrogate Endpoint (SUR): Blood pressure
Study 35660514 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 35984916 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35984916 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34837121 — Safety Biomarker (SAF): Interleukin 1
Study 36118833 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32409691 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 34000629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34000629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34000629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33259001 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33259001 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32267573 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 33527139 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32176044 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 34587373 — Surrogate Endpoint (SUR): Blood pressure
Study 33601858 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 32524129 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32524129 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32524129 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32524129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32524129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32191400 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 36205206 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 36205206 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35345950 — Surrogate Endpoint (SUR): Blood pressure
Study 34059572 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35932209 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 35932209 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 32080148 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 32080148 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 34402135 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 35255966 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35255966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35255966 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32144056 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 32493383 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32061387 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32910863 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36331590 — Predictive Biomarker (PRD): PNN mRNA
Genes: PNN; DRS; MEMA
Study 32971450 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 32212297 — Surrogate Endpoint (SUR): Serum creatinine
Study 32371537 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32371537 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33185166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33185166 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 33185166 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 32107526 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32674587 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 35189351 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 32844807 — Surrogate Endpoint (SUR): Serum sodium
Study 35151415 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 32312065 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32312065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33307657 — Surrogate Endpoint (SUR): Blood pressure
Study 35395289 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 33528369 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34895291 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34957954 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 35556335 — Surrogate Endpoint (SUR): Blood pressure
Study 32333883 — Surrogate Endpoint (SUR): Blood pressure
Study 32681461 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 35246425 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study 33874971 — Predictive Biomarker (PRD): RAB3D mRNA
Genes: RAB3D; GOV; RAB16
Study 35674613 — Predictive Biomarker (PRD): SLA mRNA
Genes: SLA; SLAP; SLAP1
Study 35674613 — Predictive Biomarker (PRD): RGR mRNA
Genes: RGR
Study 35333363 — Surrogate Endpoint (SUR): Blood pressure
Study 35333363 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32272501 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 35766037 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 33651099 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 35183768 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 32736592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32883108 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32785614 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 32785614 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34537675 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34537675 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34537675 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 34753557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34753557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34753557 — Surrogate Endpoint (SUR): Serum creatinine
Study 34753557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34081058 — Predictive Biomarker (PRD): SPR mRNA
Genes: SPR
Study 33933267 — Surrogate Endpoint (SUR): Probing pocket depth
Study 35568804 — Surrogate Endpoint (SUR): Blood pressure
Study 35237863 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 34119909 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34119909 — Surrogate Endpoint (SUR): Blood pressure
Study 32959110 — Surrogate Endpoint (SUR): Blood pressure
Study 36038163 — Predictive Biomarker (PRD): INSM1 mRNA
Genes: INSM1; IA1
Study 32700798 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 32700798 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32700798 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 34967368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34967368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34557930 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 33682970 — Surrogate Endpoint (SUR): Blood pressure
Study 33682970 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 33682970 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32568867 — Monitoring Biomarker (MOI): HBV DNA
Study 33748055 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33748055 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33748055 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33748055 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32017167 — Safety Biomarker (SAF): Reactive oxygen species
Study 32017167 — Surrogate Endpoint (SUR): Sperm parameters
Study 35560305 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 35560305 — Surrogate Endpoint (SUR): Blood pressure
Study 34438029 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 34438029 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study 34438029 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34737549 — Safety Biomarker (SAF): Hyaluronic acid
Study 32105353 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 33414503 — Surrogate Endpoint (SUR): Blood pressure
Study 32316129 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35233923 — Predictive Biomarker (PRD): PSMB6 mRNA
Genes: PSMB6; LMPY; Y
Study 35473345 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 34554649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32622781 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 33434704 — Surrogate Endpoint (SUR): Blood pressure
Study 33450430 — Surrogate Endpoint (SUR): Bone mineral density
Study 35912647 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 34339469 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 36456477 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 34237608 — Safety Biomarker (SAF): miR-1
Study 35024154 — Surrogate Endpoint (SUR): Blood pressure
Study 35024154 — Surrogate Endpoint (SUR): Serum creatinine
Study 34157981 — Surrogate Endpoint (SUR): Blood pressure
Study 36317442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36317442 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 33113567 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 33113567 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 33113567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32046865 — Surrogate Endpoint (SUR): Serum calcium
Study 32747013 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 32747013 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32210440 — Predictive Biomarker (PRD): TGFBR1 mRNA
Genes: TGFBR1; ALK5; SKR4
Study 32210440 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 32210440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 34696742 — Surrogate Endpoint (SUR): Blood pressure