TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT06440642 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04775056 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04775056 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05166070 — Predictive Biomarker (PRD): MSLN mRNA
Genes: MSLN; MPF
Study NCT05606484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05606484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05048758 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT06404723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06673511 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT00723814 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05653856 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04544189 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT04544189 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05814627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06334120 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT05987423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05080790 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT06581406 — Predictive Biomarker (PRD): RP2 mRNA
Genes: RP2
Study NCT04747431 — Predictive Biomarker (PRD): GRN mRNA
Genes: GRN
Study NCT04747431 — Pharmacodynamic Biomarker (PDY): Guanine nucleotide exchange factor C9orf72
Genes: C9orf72; DENND9; DENNL72
Study NCT06380751 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06380751 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06380751 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT06380751 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT06380751 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05564390 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study NCT06273241 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT06291064 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT06514898 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT06514898 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04956432 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT05752097 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05382741 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT05088759 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06563596 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05587491 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT06492278 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study NCT06495723 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study NCT06343805 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT05231785 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study NCT04524442 — Surrogate Endpoint (SUR): Serum potassium
Study NCT05498935 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study NCT05643638 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT05986097 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04755153 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05464810 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05464810 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06011213 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04783766 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT06646042 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT06421935 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study NCT06250036 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06250036 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study NCT06578195 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT06578195 — Predictive Biomarker (PRD): TYRO3 mRNA
Genes: TYRO3; BYK; DTK; RSE; SKY; TIF
Study NCT06515002 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT05455619 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT05455619 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT05455619 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT05455619 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study NCT05455619 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06284317 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05523830 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04927416 — Predictive Biomarker (PRD): SSTR2 mRNA
Genes: SSTR2
Study NCT04842877 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study NCT06341647 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06341647 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06268886 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05236764 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04592211 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study NCT04592211 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT04592211 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06659341 — Predictive Biomarker (PRD): SOS1 mRNA
Genes: SOS1
Study NCT06659341 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05472818 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study NCT06609083 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06612203 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06612203 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06541704 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT06541704 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT06541704 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05656742 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05451810 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06628310 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06548607 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05284240 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04803409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05570838 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT05114967 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06130228 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT04623567 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05398224 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT06151301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05271994 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study NCT06639074 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT05528549 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06324981 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05530317 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05530317 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT05909072 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05078255 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT05460793 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05143996 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT04747561 — Predictive Biomarker (PRD): PEG3 mRNA
Genes: PEG3; KIAA0287; ZSCAN24
Study NCT06334107 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT05656222 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study NCT05296772 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study NCT05296772 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT06513975 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06705192 — Predictive Biomarker (PRD): GRN mRNA
Genes: GRN
Study NCT06709521 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT06709521 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06709781 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06719544 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06723665 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06735638 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study NCT06758206 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06769269 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06769633 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06780618 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06126276 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06126276 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06126276 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05902494 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04932577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06130553 — Predictive Biomarker (PRD): MTAP mRNA
Genes: MTAP; MSAP
Study NCT05977335 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05902845 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT06046599 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT06046599 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06322446 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT06322446 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05766540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05766540 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00000777 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06270628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04899011 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study NCT05981352 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04973163 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06515678 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT06515678 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06515678 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT06515678 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05793307 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT04779216 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05172271 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06497374 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT06095440 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06647511 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06150924 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05113810 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05979038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04788459 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06614270 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04599712 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04599712 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05860803 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study NCT05860803 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06698848 — Predictive Biomarker (PRD): TP63 mRNA
Genes: TP63; KET; P63; P73H; P73L; TP73L
Study NCT06699238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06699238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06699238 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT06518486 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05808582 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05808582 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05808582 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04299152 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05475028 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05028699 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05371275 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05246943 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT06299670 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05861570 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06516107 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT06383572 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study NCT06549296 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05672095 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06348225 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06082635 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05104866 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05104866 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05297214 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05871658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05871658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05871658 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT05769413 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05454475 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04934995 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05996627 — Predictive Biomarker (PRD): ROCK2 mRNA
Genes: ROCK2; KIAA0619
Study NCT00290069 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04637763 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06314932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06314932 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06314932 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06314932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05768880 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05768880 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT05768880 — Predictive Biomarker (PRD): CD276 mRNA
Genes: CD276; B7H3; PSEC0249; UNQ309/PRO352
Study NCT05310968 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study NCT06195306 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05151484 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04848467 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05623033 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05366816 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT04352400 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT04839185 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study NCT04911166 — Safety Biomarker (SAF): Interleukin 12
Study NCT04724421 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06221215 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT06014697 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT06514183 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT06590064 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06587789 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06587789 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06696599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06696599 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT06424340 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT05598957 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT06511479 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06254183 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT06254183 — Predictive Biomarker (PRD): DKK3 mRNA
Genes: DKK3; REIC; UNQ258/PRO295
Study NCT00000958 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study NCT00000958 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05286788 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT05286788 — Predictive Biomarker (PRD): MAP2K2 mRNA
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study NCT05286788 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study NCT04752072 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT04790331 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06004713 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT05089266 — Predictive Biomarker (PRD): MSLN mRNA
Genes: MSLN; MPF
Study NCT04747418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06397118 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT04761042 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06009393 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04643574 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00000870 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00000870 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04638816 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03904069 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05282966 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT06308406 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study NCT05071300 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT05948813 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05805826 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05950867 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT05681286 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05681286 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT06445244 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06152718 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06285422 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT06381739 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT06381739 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06381739 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04931524 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study NCT06116721 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study NCT05463575 — Predictive Biomarker (PRD): KHK mRNA
Genes: KHK
Study NCT05794659 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06226753 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT06622226 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study NCT06698744 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04919811 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT04989816 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05730829 — Safety Biomarker (SAF): BDNF
Study NCT05730829 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT05773092 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06244875 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06287944 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT05600387 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05803109 — Surrogate Endpoint (SUR): Bacterial count
Study NCT06125197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06125197 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05416827 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor