TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05491785 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study NCT04895761 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04895761 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05518578 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study NCT06424730 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04825327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04825327 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04726761 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05480865 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05300438 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05300438 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05300438 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT05300438 — Predictive Biomarker (PRD): CDK8 mRNA
Genes: CDK8
Study NCT05453669 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05825872 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT05106699 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05437497 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05246345 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT06426017 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study NCT04823351 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05361447 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study NCT05844215 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT05048524 — Predictive Biomarker (PRD): TP53INP2 mRNA
Genes: TP53INP2; C20orf110; DOR; PINH
Study NCT05130125 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT06046703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT05786729 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04830267 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05137561 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06492863 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT06253039 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT06027307 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06358430 — Predictive Biomarker (PRD): TACSTD2 mRNA
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study NCT05817812 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT05817812 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT04100694 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04100694 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT04100694 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study NCT06332417 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06539039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06539039 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT06473909 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT04970004 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT05524844 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study NCT05524844 — Predictive Biomarker (PRD): NOTCH3 mRNA
Genes: NOTCH3
Study NCT04928261 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04928261 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05191914 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05017025 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05017025 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT06495125 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study NCT04812600 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05542238 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06394466 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT06394466 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT05207800 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study NCT06218498 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT02238457 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT06540612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06540612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06540612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05581732 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT06522776 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT05211557 — Predictive Biomarker (PRD): CD276 mRNA
Genes: CD276; B7H3; PSEC0249; UNQ309/PRO352
Study NCT05412914 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT05941819 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study NCT05030675 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study NCT00000659 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04428801 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00000690 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT04835675 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05971576 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT05971576 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05376280 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT05801419 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05334446 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05740956 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study NCT05740956 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT05124990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05751018 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05751018 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05751018 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study NCT04734470 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05920135 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05469503 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06361641 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT06361641 — Predictive Biomarker (PRD): CALR mRNA
Genes: CALR; CRTC
Study NCT06361641 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study NCT05772897 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study NCT05294198 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05294198 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04506983 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT05276011 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04874740 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06339398 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05791279 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05768490 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05536323 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04647292 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05460091 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06271616 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05319249 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study NCT05319249 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study NCT04662931 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06399926 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06399926 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06399926 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT05972629 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01128010 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT06193122 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05044299 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06558422 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT06525155 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT05549921 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT06480565 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT05445245 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study NCT05983081 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06332807 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT05701319 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT05701319 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03843008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06536686 — Safety Biomarker (SAF): MTHFR
Study NCT06461910 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05340985 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT05957926 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05398731 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04420364 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05116774 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT05595278 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT05969847 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05371483 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05651178 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05651178 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT06446557 — Predictive Biomarker (PRD): WIF1 mRNA
Genes: WIF1; UNQ191/PRO217
Study NCT06446557 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study NCT06446557 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05438667 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05032820 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05187832 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05187832 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05187832 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05466201 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT04986566 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06106906 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05352542 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT00000771 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05663866 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05663866 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05548088 — Predictive Biomarker (PRD): LILRB4 mRNA
Genes: LILRB4; ILT3; LIR5
Study NCT06619886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT06619886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT06254534 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04315818 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study NCT06471283 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06731673 — Predictive Biomarker (PRD): SERPINH1 mRNA
Genes: SERPINH1; CBP1; CBP2; HSP47; SERPINH2; PIG14
Study NCT05033392 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT06547476 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05269056 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT06319950 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03433807 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06731153 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT06418139 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT04798651 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04882774 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT04691414 — Predictive Biomarker (PRD): SHH mRNA
Genes: SHH
Study NCT05677685 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06185010 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06043544 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04197648 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06307678 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT06307678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05794802 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05794802 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05963828 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04900350 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study NCT05606133 — Monitoring Biomarker (MOI): Cell-free HPV DNA
Study NCT00935896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00935896 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT00710216 — Monitoring Biomarker (MOI): HBV DNA
Study NCT06271837 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05012228 — Predictive Biomarker (PRD): LTBP4 mRNA
Genes: LTBP4
Study NCT05873218 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06317363 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00002309 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05673343 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT05672043 — Predictive Biomarker (PRD): SHH mRNA
Genes: SHH
Study NCT05518318 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT05859477 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT05859477 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06420401 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT06491199 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05391789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06565611 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT05335473 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05335473 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05335473 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06516926 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05191160 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05011370 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study NCT05222633 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06632379 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06727773 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06727773 — Safety Biomarker (SAF): BDNF
Study NCT06763614 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT06496373 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05203588 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06764043 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study NCT06764043 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study NCT06329284 — Predictive Biomarker (PRD): MDK mRNA
Genes: MDK; MK1; NEGF2
Study NCT06329284 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05813041 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04826549 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT06354205 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT06354205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06354205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05000515 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06764420 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT05061303 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT06333873 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT06764121 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05191368 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06430099 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06763666 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06763354 — Predictive Biomarker (PRD): PTK7 mRNA
Genes: PTK7; CCK4
Study NCT06762977 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05366283 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05087615 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT05546580 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT04645719 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06536088 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study NCT05815186 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06247254 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04390087 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06523413 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05536271 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT05536271 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05918380 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05527457 — Predictive Biomarker (PRD): KCNK3 mRNA
Genes: KCNK3; TASK; TASK1
Study NCT05367882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05367882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05367882 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT06426160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05699811 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05219916 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT05219916 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06228677 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04784442 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06515795 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05496595 — Predictive Biomarker (PRD): CD93 mRNA
Genes: CD93; C1QR1; MXRA4
Study NCT05167240 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05622747 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study NCT05622747 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study NCT05998837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04908059 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04578652 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05299853 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT04717999 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study NCT04276909 — Predictive Biomarker (PRD): LUM mRNA
Genes: LUM; LDC; SLRR2D
Study NCT04665089 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05818865 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT05818865 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT06367712 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05841914 — Predictive Biomarker (PRD): TRPV2 mRNA
Genes: TRPV2; VRL
Study NCT05079360 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05079360 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05005039 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04189133 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT04189133 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT05871671 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06231771 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22