TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32066625 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 32611505 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35080109 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 35080109 — Surrogate Endpoint (SUR): Blood pressure
Study 35080109 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 33175117 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33175117 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33175117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33417146 — Surrogate Endpoint (SUR): Blood pressure
Study 32075818 — Predictive Biomarker (PRD): DCT mRNA
Genes: DCT; TYRP2
Study 33026938 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35597518 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 35393715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35393715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35393715 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32785940 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32785940 — Safety Biomarker (SAF): Derived neutrophil to lymphocyte
Study 32891286 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32161005 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32161005 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35124808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34934009 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 32088668 — Surrogate Endpoint (SUR): Blood pressure
Study 34197338 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 36197920 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 34245031 — Surrogate Endpoint (SUR): Blood pressure
Study 32129263 — Surrogate Endpoint (SUR): Blood pressure
Study 32129263 — Surrogate Endpoint (SUR): Serum sodium
Study 33849821 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 33849821 — Predictive Biomarker (PRD): MAPK1 mRNA
Genes: MAPK1; ERK2; PRKM1; PRKM2
Study 33849821 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 33849821 — Predictive Biomarker (PRD): PTPN11 mRNA
Genes: PTPN11; PTP2C; SHPTP2
Study 33849821 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33849821 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33849821 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 33849821 — Predictive Biomarker (PRD): KNG1 mRNA
Genes: KNG1; BDK; KNG
Study 32138563 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 35199478 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35199478 — Surrogate Endpoint (SUR): Serum potassium
Study 35199478 — Surrogate Endpoint (SUR): Blood pressure
Study 34426064 — Surrogate Endpoint (SUR): Blood pressure
Study 34287475 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 34596269 — Surrogate Endpoint (SUR): Serum testosterone
Study 34655400 — Predictive Biomarker (PRD): MAGT1 mRNA
Genes: MAGT1; IAG2; PSEC0084; UNQ628/PRO1244
Study 34655400 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 35488724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35377706 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 616401931 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 37212758 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32359899 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35778941 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 32738298 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35599701 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34499665 — Predictive Biomarker (PRD): DCXR mRNA
Genes: DCXR; SDR20C1
Study 33651090 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 616518461 — Surrogate Endpoint (SUR): Serum creatinine
Study 35737735 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35737735 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 34318633 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32345916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36050653 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 35657762 — Surrogate Endpoint (SUR): Blood pressure
Study 35452414 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35713846 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 35713846 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32657261 — Surrogate Endpoint (SUR): Serum uric acid
Study 33288685 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 33288685 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 32843515 — Predictive Biomarker (PRD): DRAM1 mRNA
Genes: DRAM1; DRAM
Study 32843515 — Predictive Biomarker (PRD): DRAM2 mRNA
Genes: DRAM2; TMEM77; PSEC0031; UNQ154/PRO180
Study 35093510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32632078 — Surrogate Endpoint (SUR): Blood pressure
Study 33577011 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33466137 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33466137 — Predictive Biomarker (PRD): ELP1 mRNA
Genes: ELP1; IKAP; IKBKAP
Study 34056698 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 32184123 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 32184123 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33685854 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32079968 — Surrogate Endpoint (SUR): Blood pressure
Study 34782191 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 34782191 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33060531 — Surrogate Endpoint (SUR): Serum creatinine
Study 32187256 — Surrogate Endpoint (SUR): Blood pressure
Study 35348584 — Monitoring Biomarker (MOI): miR-99b
Genes: MIR99B
Study 33930204 — Safety Biomarker (SAF): Hyaluronic acid
Study 35843106 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 32333898 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35449020 — Surrogate Endpoint (SUR): Serum sodium
Study 32921252 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 33966560 — Surrogate Endpoint (SUR): Blood pressure
Study 36146869 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36146869 — Predictive Biomarker (PRD): LSAMP mRNA
Genes: LSAMP; IGLON3; LAMP
Study 33798303 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 34271194 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 36044330 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36044330 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36044330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33439308 — Monitoring Biomarker (MOI): Cell-free DNA
Study 35061005 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33418490 — Safety Biomarker (SAF): miR-214
Genes: MIR214
Study 32173464 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34969566 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 34969566 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34969566 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 34454044 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33738521 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32773223 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35894933 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32332664 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32332664 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32729897 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 32729897 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36420523 — Surrogate Endpoint (SUR): Blood pressure
Study 32962673 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 32127657 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 32907792 — Surrogate Endpoint (SUR): Blood pressure
Study 32711460 — Surrogate Endpoint (SUR): Blood pressure
Study 33023589 — Surrogate Endpoint (SUR): Blood pressure
Study 36079139 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 34739763 — Surrogate Endpoint (SUR): Blood pressure
Study 32507439 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34737187 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34521135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33232714 — Surrogate Endpoint (SUR): Blood pressure
Study 32491932 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 32491932 — Predictive Biomarker (PRD): TYRO3 mRNA
Genes: TYRO3; BYK; DTK; RSE; SKY; TIF
Study 32491932 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 32491932 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 35538185 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 32896498 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32896498 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 32896498 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32896498 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32896498 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32896498 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 32353536 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 36103212 — Safety Biomarker (SAF): Reactive oxygen species
Study 36103212 — Surrogate Endpoint (SUR): Blood pressure
Study 35904063 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 35904063 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33132094 — Surrogate Endpoint (SUR): Bone mineral density
Study 36116516 — Surrogate Endpoint (SUR): Blood pressure
Study 32412358 — Surrogate Endpoint (SUR): Blood pressure
Study 35478433 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 35478433 — Surrogate Endpoint (SUR): Blood pressure
Study 36247425 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 35500966 — Surrogate Endpoint (SUR): Blood pressure
Study 34048587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34048587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36056351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33403940 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33403940 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 34193262 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35704085 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 32037213 — Surrogate Endpoint (SUR): Blood pressure
Study 35988522 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35027013 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 33764803 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34315492 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 32476277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35443108 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 32404130 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33228773 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 36127661 — Surrogate Endpoint (SUR): Blood pressure
Study 35605188 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 33098995 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33098995 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 33098995 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 33098995 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 33098995 — Predictive Biomarker (PRD): Hormone receptor
Study 33855585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35889902 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 32692751 — Surrogate Endpoint (SUR): Blood pressure
Study 32692751 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35334900 — Predictive Biomarker (PRD): EHF mRNA
Genes: EHF; ESE3; ESE3B; ESEJ
Study 34788233 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35970278 — Surrogate Endpoint (SUR): Blood pressure
Study 35556322 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35556322 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study 35556322 — Surrogate Endpoint (SUR): Blood pressure
Study 33117349 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 34999610 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 35368954 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 35368954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 35368954 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 33004239 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 33759846 — Predictive Biomarker (PRD): EBP mRNA
Genes: EBP
Study 32467145 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 32467145 — Predictive Biomarker (PRD): CRLF2 mRNA
Genes: CRLF2; CRL2; ILXR; TSLPR
Study 32467145 — Predictive Biomarker (PRD): IKZF1 mRNA
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 32467145 — Predictive Biomarker (PRD): BTG1 mRNA
Genes: BTG1
Study 32467145 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 32687588 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32687588 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34579095 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32895043 — Surrogate Endpoint (SUR): Blood pressure
Study 32340074 — Predictive Biomarker (PRD): CPQ mRNA
Genes: CPQ; LCH1; PGCP
Study 34423370 — Surrogate Endpoint (SUR): Serum potassium
Study 33676870 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33676870 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33676870 — Predictive Biomarker (PRD): Hormone receptor
Study 37552627 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 36113201 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 34648905 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 32619388 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 36181992 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 36181992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34272849 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32561603 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35242203 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35242203 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35242203 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33934076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32041720 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33218513 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 33059633 — Surrogate Endpoint (SUR): Blood pressure
Study 34268944 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36006997 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34177914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34177914 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 34177914 — Predictive Biomarker (PRD): GNLY mRNA
Genes: GNLY; LAG2; NKG5; TLA519
Study 34177914 — Predictive Biomarker (PRD): IFI35 mRNA
Genes: IFI35; IFP35
Study 34177914 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 34177914 — Predictive Biomarker (PRD): CLEC7A mRNA
Genes: CLEC7A; BGR; CLECSF12; DECTIN1; UNQ539/PRO1082
Study 34177914 — Predictive Biomarker (PRD): TAGAP mRNA
Genes: TAGAP; TAGAP1; FKSG15
Study 33787632 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36249235 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 36249235 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32661605 — Surrogate Endpoint (SUR): Blood pressure
Study 32473624 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 33438846 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 33032655 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 32457995 — Predictive Biomarker (PRD): CTRC mRNA
Genes: CTRC; CLCR
Study 32653904 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 32653904 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 32653904 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32653904 — Surrogate Endpoint (SUR): Blood pressure
Study 33685395 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 35172043 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 35172043 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 33649520 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 33649520 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HSD3B1 mRNA
Genes: HSD3B1; 3BH; HSDB3A
Study 33649520 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 33649520 — Predictive Biomarker (PRD): ADD3 mRNA
Genes: ADD3; ADDL
Study 34593725 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34593725 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32271358 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 34003963 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 34324065 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33828260 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 35241369 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35241369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33825304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33825304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33825304 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 34788698 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33895829 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 33895829 — Surrogate Endpoint (SUR): Blood pressure
Study 34921023 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33152285 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33152285 — Predictive Biomarker (PRD): Hormone receptor
Study 35365783 — Surrogate Endpoint (SUR): Blood pressure
Study 33386021 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 32846798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32846798 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35451381 — Predictive Biomarker (PRD): PDPN mRNA
Genes: PDPN; GP36; PSEC0003; PSEC0025
Study 35158465 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study 33435919 — Predictive Biomarker (PRD): MAP3K10 mRNA
Genes: MAP3K10; MLK2; MST
Study 34236037 — Surrogate Endpoint (SUR): Blood pressure
Study 33938135 — Predictive Biomarker (PRD): CRACR2A mRNA
Genes: CRACR2A; EFCAB4B; RAB46
Study 33938135 — Predictive Biomarker (PRD): FARP1 mRNA
Genes: FARP1; CDEP; PLEKHC2