TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33647676 — Surrogate Endpoint (SUR): Blood pressure
Study 35578345 — Surrogate Endpoint (SUR): Blood pressure
Study 33660924 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33660924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33660924 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33660924 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 616996904 — Surrogate Endpoint (SUR): Blood pressure
Study 36135432 — Surrogate Endpoint (SUR): Blood pressure
Study 36135432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36135432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36135432 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 33375429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 36052011 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36052011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36052011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33468225 — Surrogate Endpoint (SUR): Blood pressure
Study 34057299 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34739914 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34875965 — Surrogate Endpoint (SUR): Blood pressure
Study 35818198 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 33693537 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35977831 — Surrogate Endpoint (SUR): Blood pressure
Study 34424565 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34564985 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study 34564985 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34564985 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 34564985 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33499139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35183780 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 34600585 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 35795313 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 34836388 — Predictive Biomarker (PRD): IFIH1 mRNA
Genes: IFIH1; MDA5; RH116
Study 34836388 — Predictive Biomarker (PRD): MX1 mRNA
Genes: MX1
Study 34836388 — Predictive Biomarker (PRD): ISG15 mRNA
Genes: ISG15; G1P2; UCRP
Study 32635352 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33085032 — Predictive Biomarker (PRD): Hormone receptor
Study 35791768 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34385707 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34747972 — Surrogate Endpoint (SUR): Blood pressure
Study 33347003 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 33347003 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 33347003 — Safety Biomarker (SAF): Hyaluronic acid
Study 34353046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34353046 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 34353046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32362552 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32404854 — Predictive Biomarker (PRD): LHPP mRNA
Genes: LHPP
Study 33668564 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32594785 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32594785 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35199968 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34896732 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34112734 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 33682773 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33050362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33050362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33050362 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 616871163 — Predictive Biomarker (PRD): ROCK2 mRNA
Genes: ROCK2; KIAA0619
Study 616871163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 616871163 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34625284 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34625284 — Predictive Biomarker (PRD): Hormone receptor
Study 32058362 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study 34623899 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 34623899 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32804843 — Safety Biomarker (SAF): Hyaluronic acid
Study 34922353 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 34922353 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35867073 — Predictive Biomarker (PRD): ILK mRNA
Genes: ILK; ILK1; ILK2
Study 35858590 — Surrogate Endpoint (SUR): Pathological complete response
Study 33792788 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35065922 — Surrogate Endpoint (SUR): Blood pressure
Study 35026851 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 35222879 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 33831949 — Surrogate Endpoint (SUR): Serum calcium
Study 34431071 — Surrogate Endpoint (SUR): Annualized growth velocity
Study 34431071 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 34253584 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34253584 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 32493720 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34724899 — Surrogate Endpoint (SUR): Blood pressure
Study 33289822 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33120757 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 33120757 — Surrogate Endpoint (SUR): Sperm parameters
Study 34320232 — Predictive Biomarker (PRD): ATP7B mRNA
Genes: ATP7B; PWD; WC1; WND
Study 33190991 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 35279069 — Monitoring Biomarker (MOI): Procalcitonin
Study 35279069 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32723107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35447274 — Surrogate Endpoint (SUR): Bone mineral density
Study 32698144 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 32703721 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 32703721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32703721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33823606 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 33619014 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 32686972 — Surrogate Endpoint (SUR): Blood pressure
Study 33827700 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 34856706 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33492879 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33492879 — Surrogate Endpoint (SUR): Blood pressure
Study 34593526 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 34593526 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 32428786 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 33564824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 35868622 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 34330458 — Surrogate Endpoint (SUR): Blood pressure
Study 35486131 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35486131 — Surrogate Endpoint (SUR): Blood pressure
Study 34850039 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 34380636 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32579195 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32540337 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32769849 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 32574006 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 34110580 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 616788753 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33420104 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33160571 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 35345654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35345654 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35502412 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 32889867 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 34075857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34365456 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 32475312 — Surrogate Endpoint (SUR): Blood pressure
Study 33357420 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33357420 — Predictive Biomarker (PRD): Hormone receptor
Study 33357420 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35943897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35943897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32724270 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 34475898 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34413344 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 34125980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34125980 — Safety Biomarker (SAF): miR-181a
Study 32119093 — Surrogate Endpoint (SUR): Blood pressure
Study 36297080 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 36297080 — Surrogate Endpoint (SUR): Blood pressure
Study 33993905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33031517 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32036693 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 35090529 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33790049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34340632 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 36397218 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 34323244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32452352 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34276366 — Surrogate Endpoint (SUR): Serum creatinine
Study 34495953 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 34495953 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 33297458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32513251 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34143215 — Surrogate Endpoint (SUR): Blood pressure
Study 32267934 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32267934 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33586474 — Surrogate Endpoint (SUR): Blood pressure
Study 36220712 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 32147032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32147032 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 32219497 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 35766592 — Surrogate Endpoint (SUR): Blood pressure
Study 33041226 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 33041226 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33041226 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 33041226 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 33041226 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 33041226 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35919499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35919499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33372675 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35799662 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 35121623 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 35121623 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35121623 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 32687088 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32687088 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35468580 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34281611 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 34281611 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 35120457 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 33406353 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34652088 — Surrogate Endpoint (SUR): Blood pressure
Study 34510814 — Surrogate Endpoint (SUR): Serum testosterone
Study 34510814 — Surrogate Endpoint (SUR): Bone mineral density
Study 33162294 — Surrogate Endpoint (SUR): Probing pocket depth
Study 36483124 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 34034372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33374006 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study 33374006 — Predictive Biomarker (PRD): CES1 mRNA
Genes: CES1; CES2; SES1
Study 33374006 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 33374006 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 33374006 — Predictive Biomarker (PRD): HNF4A mRNA
Genes: HNF4A; HNF4; NR2A1; TCF14
Study 33374006 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 33011172 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 33011172 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 33011172 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33011172 — Predictive Biomarker (PRD): TP53I3 mRNA
Genes: TP53I3; PIG3
Study 33011172 — Predictive Biomarker (PRD): COX6B1 mRNA
Genes: COX6B1; COX6B
Study 33011172 — Predictive Biomarker (PRD): DERA mRNA
Genes: DERA; CGI-26
Study 33011172 — Predictive Biomarker (PRD): FIS1 mRNA
Genes: FIS1; TTC11; CGI-135
Study 33011172 — Predictive Biomarker (PRD): NDUFA1 mRNA
Genes: NDUFA1
Study 33011172 — Predictive Biomarker (PRD): NDUFA4 mRNA
Genes: NDUFA4
Study 33011172 — Predictive Biomarker (PRD): PRDX2 mRNA
Genes: PRDX2; NKEFB; TDPX1
Study 36307493 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36307493 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 33739883 — Surrogate Endpoint (SUR): Blood pressure
Study 33739883 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33739883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33774921 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 33774921 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 35872448 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 32723374 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 32723374 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 32723374 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32723374 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 32723374 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 32723374 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 32723374 — Predictive Biomarker (PRD): VCAM1 mRNA
Genes: VCAM1
Study 32723374 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 32723374 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 32723374 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 32723374 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 32859615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32859615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32859615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35464450 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 35464450 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35464450 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 32920219 — Surrogate Endpoint (SUR): Serum creatinine
Study 33118847 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 35066653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35066653 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35066653 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 32789898 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 35656851 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 32665040 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36501136 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 33988948 — Surrogate Endpoint (SUR): Bone mineral density
Study 33988948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 35636341 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32710584 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 32710584 — Safety Biomarker (SAF): Hyaluronic acid
Study 32115759 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study 35398241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35398241 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34174970 — Surrogate Endpoint (SUR): Blood pressure
Study 33357008 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33357008 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34791324 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33337109 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 33337109 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 33337109 — Surrogate Endpoint (SUR): Blood pressure
Study 32591295 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32894967 — Surrogate Endpoint (SUR): Blood pressure
Study 34843940 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34843940 — Predictive Biomarker (PRD): Microsatellite instability
Study 35926756 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 35926756 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 35926756 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26