TrialPanorama/TrialPanorama-database huggingface dataset:
Study 38922488 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38923871 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 38924124 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 38924124 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 38924429 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 38924429 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 38924456 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38924456 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 38924481 — Surrogate Endpoint (SUR): Blood pressure
Study 38924731 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 38924731 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 38924732 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 38924779 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 38925110 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 38925586 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 38925694 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 38925803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38926142 — Safety Biomarker (SAF): BDNF
Study 38926142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38926142 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 38926162 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study 38926693 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 38926732 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 38926732 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 38926732 — Predictive Biomarker (PRD): KDM5D mRNA
Genes: KDM5D; HY; HYA; JARID1D; KIAA0234; SMCY
Study 38926732 — Predictive Biomarker (PRD): IGFBP5 mRNA
Genes: IGFBP5; IBP5
Study 38926732 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 38926732 — Predictive Biomarker (PRD): SLC15A1 mRNA
Genes: SLC15A1; PEPT1
Study 38926732 — Predictive Biomarker (PRD): XPNPEP2 mRNA
Genes: XPNPEP2
Study 38926732 — Predictive Biomarker (PRD): HMGCS2 mRNA
Genes: HMGCS2
Study 38926732 — Predictive Biomarker (PRD): DDX3Y mRNA
Genes: DDX3Y; DBY
Study 38926753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38926810 — Predictive Biomarker (PRD): TBP mRNA
Genes: TBP; GTF2D1; TF2D; TFIID
Study 38927991 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 38931260 — Predictive Biomarker (PRD): HLA-DMB mRNA
Genes: HLA-DMB; DMB; RING7
Study 38931864 — Predictive Biomarker (PRD): ALG11 mRNA
Genes: ALG11; GT8
Study 38932589 — Predictive Biomarker (PRD): CKM mRNA
Genes: CKM; CKMM
Study 38932723 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 38932723 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 38934093 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 38934093 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 38934093 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 38934093 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 38934093 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 38934093 — Predictive Biomarker (PRD): MMP12 mRNA
Genes: MMP12; HME
Study 38934093 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 38934093 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 38934111 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 38934229 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 38934517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38934602 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 38934964 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 38934968 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38935125 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38935379 — Predictive Biomarker (PRD): Hormone receptor
Study 38935839 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38935923 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38935923 — Predictive Biomarker (PRD): Hormone receptor
Study 38936378 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 38936379 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 38936550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38936550 — Surrogate Endpoint (SUR): Blood pressure
Study 38937298 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38937298 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 38937298 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 38937298 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 38937331 — Surrogate Endpoint (SUR): Bone mineral density
Study 38937404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38937446 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 38937446 — Predictive Biomarker (PRD): NTRK2 mRNA
Genes: NTRK2; TRKB
Study 38937446 — Predictive Biomarker (PRD): NTRK
Study 38937803 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 38937803 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38937954 — Predictive Biomarker (PRD): VCP mRNA
Genes: VCP
Study 38938387 — Predictive Biomarker (PRD): SAGE1 mRNA
Genes: SAGE1; SAGE
Study 38938412 — Surrogate Endpoint (SUR): Blood pressure
Study 38938704 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 38939456 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 38939518 — Predictive Biomarker (PRD): TNFRSF14 mRNA
Genes: TNFRSF14; HVEA; HVEM; UNQ329/PRO509
Study 38939518 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study 38939580 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 38939828 — Surrogate Endpoint (SUR): Bone mineral density
Study 38940282 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 38940981 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38940981 — Predictive Biomarker (PRD): Hormone receptor
Study 38941376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38941599 — Safety Biomarker (SAF): Hyaluronic acid
Study 38941601 — Surrogate Endpoint (SUR): Blood pressure
Study 38941963 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 38942047 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 38942592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38942592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38942601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38942601 — Safety Biomarker (SAF): Interleukin 1
Study 38942993 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 38942995 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 38942995 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 38942995 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 38943014 — Surrogate Endpoint (SUR): Blood pressure
Study 38943664 — Predictive Biomarker (PRD): PI3 mRNA
Genes: PI3; WAP3; WFDC14
Study 38944147 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 38945140 — Surrogate Endpoint (SUR): Blood pressure
Study 38945800 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 38946010 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 38946010 — Surrogate Endpoint (SUR): Blood pressure
Study 38946973 — Predictive Biomarker (PRD): SOAT1 mRNA
Genes: SOAT1; ACACT; ACACT1; ACAT; ACAT1; SOAT; STAT
Study 38947035 — Predictive Biomarker (PRD): CDCP1 mRNA
Genes: CDCP1; TRASK; UNQ2486/PRO5773
Study 38947035 — Predictive Biomarker (PRD): CD6 mRNA
Genes: CD6
Study 38947093 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38947093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38948164 — Surrogate Endpoint (SUR): Blood pressure
Study 38948455 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 38948837 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 38948837 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38948837 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 38949541 — Surrogate Endpoint (SUR): Blood pressure
Study 38949758 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 38949758 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 38949758 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 38950286 — Predictive Biomarker (PRD): TREX1 mRNA
Genes: TREX1
Study 38950311 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 38950311 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 38950555 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study 38950994 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 38951507 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38951803 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 38951853 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38952054 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 38953936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38954176 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study 38954176 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38954226 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 38954782 — Predictive Biomarker (PRD): FLI1 mRNA
Genes: FLI1
Study 38954834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38954844 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 38954860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38954899 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 38955554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38955811 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38955811 — Surrogate Endpoint (SUR): Blood pressure
Study 38955921 — Predictive Biomarker (PRD): RASA1 mRNA
Genes: RASA1; GAP; RASA
Study 38956196 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 38956196 — Surrogate Endpoint (SUR): Bone mineral density
Study 38956675 — Surrogate Endpoint (SUR): Blood pressure
Study 38956935 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 38958845 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 38958846 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 38958913 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 38958913 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 38958989 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 38958989 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38959017 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38959017 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 38959017 — Surrogate Endpoint (SUR): Blood pressure
Study 38959294 — Surrogate Endpoint (SUR): Blood pressure
Study 38960044 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 38960044 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 38960044 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 38960508 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38960626 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 38960798 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 38960812 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38960832 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38960907 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 38960969 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 38961193 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 38961388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 38961388 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 38961388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38961388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38961388 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 38961419 — Monitoring Biomarker (MOI): Procalcitonin
Study 38961419 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 38961419 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 38961419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 38961419 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 38961430 — Surrogate Endpoint (SUR): Blood pressure
Study 38961439 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 38961496 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 38962958 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 38963325 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 38963556 — Surrogate Endpoint (SUR): Serum creatinine
Study 38963583 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 38963799 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 38963799 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38963799 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 38964333 — Predictive Biomarker (PRD): HNF1A mRNA
Genes: HNF1A; TCF1
Study 38964420 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 38965031 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38965462 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 38965550 — Surrogate Endpoint (SUR): Bacterial count
Study 38966802 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 38966990 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 38967583 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 38967589 — Safety Biomarker (SAF): Hyaluronic acid
Study 38967884 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38968138 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study 38968138 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 38968138 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 38968138 — Predictive Biomarker (PRD): IL15 mRNA
Genes: IL15
Study 38968138 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 38968138 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 38968568 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 38968599 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 38969081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38969374 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 38969879 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38970008 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 38970037 — Surrogate Endpoint (SUR): Blood pressure
Study 38970127 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 38970256 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 38970327 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 38970587 — Surrogate Endpoint (SUR): Serum sodium
Study 38971151 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 38971151 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 38971756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38971950 — Predictive Biomarker (PRD): STING1 mRNA
Genes: STING1; ERIS; MITA; STING; TMEM173
Study 38972612 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 38972612 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38974817 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 38975711 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38976019 — Predictive Biomarker (PRD): FSTL3 mRNA
Genes: FSTL3; FLRG; UNQ674/PRO1308
Study 38976035 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 38976363 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 38977298 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 38977368 — Surrogate Endpoint (SUR): Blood pressure
Study 38977536 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38977536 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 38977536 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 38977536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 38977655 — Surrogate Endpoint (SUR): Blood pressure
Study 38977715 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 38978124 — Predictive Biomarker (PRD): DCN mRNA
Genes: DCN; SLRR1B
Study 38978309 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 38978403 — Surrogate Endpoint (SUR): Blood pressure
Study 38978673 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 38979716 — Surrogate Endpoint (SUR): Bone mineral density
Study 38979743 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 38979893 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38980082 — Safety Biomarker (SAF): Hyaluronic acid
Study 38980272 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 38980329 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 38980666 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 38980725 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 38980725 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study 38980725 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38981954 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 38981994 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 38982001 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 38982001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38982001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38982001 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 38982051 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 38982051 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 38982551 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study 38983151 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 38983151 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 38983151 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 38984118 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 38985232 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 38985232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38985247 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 38985247 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38985436 — Surrogate Endpoint (SUR): Blood pressure
Study 38985496 — Surrogate Endpoint (SUR): Blood pressure
Study 38985817 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 38985849 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 38985849 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 38985979 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA