TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35247974 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35247974 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36471186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36471186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32496902 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34159199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36226977 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 33812736 — Surrogate Endpoint (SUR): Serum potassium
Study 33809796 — Surrogate Endpoint (SUR): Blood pressure
Study 32406601 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34468979 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 32427555 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 32427555 — Safety Biomarker (SAF): Interleukin 1
Study 32427555 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 34090216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36458916 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 32006650 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 35260100 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 34001367 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34621458 — Predictive Biomarker (PRD): TBCB mRNA
Genes: TBCB; CG22; CKAP1
Study 32829456 — Surrogate Endpoint (SUR): Blood pressure
Study 32522282 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 32276134 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32276134 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32276134 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32699128 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32699128 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 32699128 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 33859411 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 32781086 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 34530882 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 35776109 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32019154 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32019154 — Safety Biomarker (SAF): MTHFR
Study 32019154 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32019154 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 34902368 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 35673701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33094725 — Surrogate Endpoint (SUR): Blood pressure
Study 34739863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34558823 — Monitoring Biomarker (MOI): HBV DNA
Study 36156115 — Surrogate Endpoint (SUR): Blood pressure
Study 32331071 — Predictive Biomarker (PRD): TAAR1 mRNA
Genes: TAAR1; TA1; TAR1; TRAR1
Study 34836278 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34375789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33408691 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 33408691 — Surrogate Endpoint (SUR): Blood pressure
Study 33780665 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 33711216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33711216 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 33711216 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 36086735 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 34042156 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 34042156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34042156 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 32011196 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 34882161 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 34882161 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 34882161 — Surrogate Endpoint (SUR): Blood pressure
Study 33664334 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 36451771 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 36451771 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33934973 — Predictive Biomarker (PRD): MAVS mRNA
Genes: MAVS; IPS1; KIAA1271; VISA
Study 32171426 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32439979 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 32436173 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 32436173 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32436173 — Safety Biomarker (SAF): Hyaluronic acid
Study 32169321 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 32460460 — Monitoring Biomarker (MOI): HBV DNA
Study 35986390 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34319506 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34319506 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33215600 — Surrogate Endpoint (SUR): Bone mineral density
Study 32607683 — Predictive Biomarker (PRD): NOX5 mRNA
Genes: NOX5
Study 32607683 — Safety Biomarker (SAF): Reactive oxygen species
Study 32607683 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 34503977 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 34503977 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 34503977 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 33120891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33120891 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 33120891 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33120891 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33120891 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33120891 — Safety Biomarker (SAF): BDNF
Study 35717239 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 35580976 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 35273807 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33184726 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32504862 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 32749918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32869592 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 32200649 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32340650 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 36375565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32212983 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32212983 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34029163 — Predictive Biomarker (PRD): LEPR mRNA
Genes: LEPR; DB; OBR
Study 33581097 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 33581097 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 34535716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34535716 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 34535716 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 34535716 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 34535716 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 34535716 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 33209019 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32691499 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33806529 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 33806529 — Surrogate Endpoint (SUR): Blood pressure
Study 32553118 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32553118 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCNE1 mRNA
Genes: CCNE1; CCNE
Study 32553118 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 32553118 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 32553118 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 32050792 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32409324 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32144833 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 32318288 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 33607312 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study 32729919 — Surrogate Endpoint (SUR): Blood pressure
Study 35033043 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 33855215 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33073779 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 33073779 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 35716695 — Predictive Biomarker (PRD): Cyclin-dependent kinase-like 5
Genes: CDKL5; STK9
Study 34578807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32811448 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32811448 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32811448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32347887 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35237340 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 35237340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35237340 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 33849908 — Surrogate Endpoint (SUR): Blood pressure
Study 33482328 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study 35081280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32901996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34890063 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 34833364 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 34953634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34953634 — Surrogate Endpoint (SUR): Blood pressure
Study 36472389 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 36472389 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 34741341 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 35197018 — Surrogate Endpoint (SUR): Blood pressure
Study 34051812 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 34051812 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 34051812 — Predictive Biomarker (PRD): NFKB2 mRNA
Genes: NFKB2; LYT10
Study 34051812 — Predictive Biomarker (PRD): NEK9 mRNA
Genes: NEK9; KIAA1995; NEK8; NERCC
Study 34051812 — Predictive Biomarker (PRD): HOXA7 mRNA
Genes: HOXA7; HOX1A
Study 32919916 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33452004 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 34327739 — Predictive Biomarker (PRD): KMO mRNA
Genes: KMO
Study 36350138 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 32012231 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 32012231 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 36241705 — Surrogate Endpoint (SUR): Blood pressure
Study 36286887 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32340903 — Surrogate Endpoint (SUR): Blood pressure
Study 34436555 — Surrogate Endpoint (SUR): Blood pressure
Study 36314474 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 33400237 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33400237 — Predictive Biomarker (PRD): C-C motif chemokine 7
Genes: CCL7; MCP3; SCYA6; SCYA7
Study 33400237 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 33773809 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33773809 — Safety Biomarker (SAF): BDNF
Study 32005277 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36501092 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 33839919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33253864 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33161684 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 32616150 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35869690 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 33230526 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35089354 — Surrogate Endpoint (SUR): Blood pressure
Study 32145474 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36231728 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 33971141 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36076452 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36076452 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36076452 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33883254 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33883254 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 32683790 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32274521 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 33967047 — Surrogate Endpoint (SUR): Blood pressure
Study 35218725 — Surrogate Endpoint (SUR): Blood pressure
Study 35346603 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36112645 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 34880010 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33128303 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33947886 — Surrogate Endpoint (SUR): Serum potassium
Study 33947886 — Surrogate Endpoint (SUR): Serum sodium
Study 33015809 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 33781915 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 33343577 — Predictive Biomarker (PRD): MCEMP1 mRNA
Genes: MCEMP1; C19orf59
Study 33343577 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 35361657 — Surrogate Endpoint (SUR): Blood pressure
Study 33296972 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 33411195 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34143698 — Surrogate Endpoint (SUR): Blood pressure
Study 32810355 — Surrogate Endpoint (SUR): Blood pressure
Study 32020414 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 36272969 — Surrogate Endpoint (SUR): Blood pressure
Study 36272969 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34721385 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 32410425 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35452830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35452830 — Monitoring Biomarker (MOI): Procalcitonin
Study 35452830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35452830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35452830 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 35452830 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 35775311 — Surrogate Endpoint (SUR): Probing pocket depth
Study 34923515 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33137378 — Predictive Biomarker (PRD): DLST mRNA
Genes: DLST; DLTS
Study 33137378 — Predictive Biomarker (PRD): ECH1 mRNA
Genes: ECH1
Study 32736344 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32736344 — Surrogate Endpoint (SUR): Blood pressure
Study 33175577 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 33175577 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 33175577 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 35853580 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35853580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35668500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35268021 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 35268021 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 35268021 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33413354 — Surrogate Endpoint (SUR): Blood pressure
Study 32462539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32462539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32462539 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 32462539 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 32242398 — Monitoring Biomarker (MOI): Procalcitonin
Study 32242398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33552050 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 33552050 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33332933 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33332933 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33332933 — Predictive Biomarker (PRD): Hormone receptor
Study 33332933 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33118053 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 34004390 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33512805 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 33512805 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 33512805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35316221 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32778945 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 33277455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35872960 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35236065 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 35708633 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 35708633 — Surrogate Endpoint (SUR): Serum triglycerides
Study 33176824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32478459 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 35112219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 32513290 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 32513290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32513290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32513290 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase