TrialPanorama/TrialPanorama-database huggingface dataset:
Study 38861192 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 38861293 — Predictive Biomarker (PRD): DLL4 mRNA
Genes: DLL4; UNQ1895/PRO4341
Study 38861293 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38861301 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study 38861666 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 38861793 — Surrogate Endpoint (SUR): Serum calcium
Study 38861871 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 38861871 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38861871 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38861871 — Predictive Biomarker (PRD): Hormone receptor
Study 38862073 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 38862251 — Safety Biomarker (SAF): Arginase-1
Genes: ARG1
Study 38862251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38862251 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 38862251 — Predictive Biomarker (PRD): APLNR mRNA
Genes: APLNR; AGTRL1; APJ
Study 38862742 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 38862908 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38862908 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 38862912 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 38862912 — Safety Biomarker (SAF): BDNF
Study 38863022 — Predictive Biomarker (PRD): NPC1 mRNA
Genes: NPC1
Study 38863717 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38864524 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 38864600 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 38864802 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 38864802 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 38864835 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 38864969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38865006 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 38865059 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 38865064 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 38865064 — Predictive Biomarker (PRD): ATOX1 mRNA
Genes: ATOX1; HAH1
Study 38865064 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 38865129 — Surrogate Endpoint (SUR): Bone mineral density
Study 38865190 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 38865671 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 38866180 — Predictive Biomarker (PRD): Microsatellite instability
Study 38866567 — Surrogate Endpoint (SUR): Blood pressure
Study 38866822 — Predictive Biomarker (PRD): SALL4 mRNA
Genes: SALL4; ZNF797
Study 38867077 — Predictive Biomarker (PRD): PSCA mRNA
Genes: PSCA; UNQ206/PRO232
Study 38867220 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 38867257 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 38867349 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 38869701 — Surrogate Endpoint (SUR): Blood pressure
Study 38869746 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 38869746 — Safety Biomarker (SAF): Interleukin 1
Study 38869771 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 38869771 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 38869771 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 38869865 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 38869865 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 38869947 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 38870573 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 38870749 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 38870931 — Predictive Biomarker (PRD): Microsatellite instability
Study 38870979 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 38871487 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 38871487 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 38871558 — Predictive Biomarker (PRD): GPRC5D mRNA
Genes: GPRC5D
Study 38871565 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 38871702 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 38871702 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 38871702 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 38871702 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 38871705 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38871705 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38871705 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 38871947 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38872109 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 38872173 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 38872480 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 38872830 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 38874618 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 38875108 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 38876132 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38876132 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 38876137 — Surrogate Endpoint (SUR): Blood pressure
Study 38876137 — Surrogate Endpoint (SUR): Serum creatinine
Study 38876657 — Predictive Biomarker (PRD): SGCE mRNA
Genes: SGCE; ESG; UNQ433/PRO840
Study 38877762 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38877777 — Predictive Biomarker (PRD): IVL mRNA
Genes: IVL
Study 38877972 — Predictive Biomarker (PRD): MBTPS1 mRNA
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 38878209 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 38879393 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 38879476 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 38879518 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 38879520 — Predictive Biomarker (PRD): SDC4 mRNA
Genes: SDC4
Study 38879559 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38879802 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 38879879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38880172 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 38880174 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38880174 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 38880251 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 38880932 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 38880932 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 38880956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38881232 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 38881232 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 38881232 — Predictive Biomarker (PRD): Microsatellite instability
Study 38881460 — Surrogate Endpoint (SUR): Blood pressure
Study 38881460 — Surrogate Endpoint (SUR): Serum creatinine
Study 38881460 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 38881599 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38881600 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 38881832 — Predictive Biomarker (PRD): STAM mRNA
Genes: STAM; STAM1
Study 38881900 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 38882712 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 38882712 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 38882712 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 38882712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 38882712 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 38882712 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 38883150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38883740 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 38883743 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38883743 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 38883779 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 38884175 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 38884175 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 38884254 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 38884900 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38884900 — Predictive Biomarker (PRD): Hormone receptor
Study 38884967 — Surrogate Endpoint (SUR): Blood pressure
Study 38884987 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 38885246 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 38885246 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study 38885246 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 38885481 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 38885481 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 38885482 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 38885672 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study 38885746 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 38885991 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 38885991 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 38886347 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38886516 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 38886516 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38886623 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 38888179 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 38888288 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study 38888480 — Predictive Biomarker (PRD): UST mRNA
Genes: UST; DS2ST
Study 38888484 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38888616 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 38888616 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 38888681 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 38888905 — Surrogate Endpoint (SUR): Blood pressure
Study 38889140 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 38889247 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 38889373 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38889373 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 38889377 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 38889737 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 38889946 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 38890164 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 38890271 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 38890271 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38890271 — Predictive Biomarker (PRD): CXCR5 mRNA
Genes: CXCR5; BLR1; MDR15
Study 38890709 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 38891799 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 38895640 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 38896056 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 38896211 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 38896223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38896229 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 38896264 — Surrogate Endpoint (SUR): Forced vital capacity
Study 38896602 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 38896602 — Predictive Biomarker (PRD): Calgranulin B
Genes: S100A9; CAGB; CFAG; MRP14
Study 38896602 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 38896602 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 38896602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 38896810 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 38896810 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 38896810 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 38896837 — Surrogate Endpoint (SUR): Blood pressure
Study 38898120 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 38898468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38899599 — Surrogate Endpoint (SUR): Probing pocket depth
Study 38899695 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 38900416 — Surrogate Endpoint (SUR): Serum calcium
Study 38900452 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 38900505 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38900773 — Surrogate Endpoint (SUR): Blood pressure
Study 38900984 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38901423 — Predictive Biomarker (PRD): SLC16A7 mRNA
Genes: SLC16A7; MCT2
Study 38901423 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 38901444 — Monitoring Biomarker (MOI): HBV DNA
Study 38901444 — Surrogate Endpoint (SUR): Bone mineral density
Study 38901559 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 38901636 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 38901858 — Surrogate Endpoint (SUR): Blood pressure
Study 38901858 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38901942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38901946 — Predictive Biomarker (PRD): HPN mRNA
Genes: HPN; TMPRSS1
Study 38902464 — Surrogate Endpoint (SUR): Blood pressure
Study 38902571 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 38902691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38902731 — Surrogate Endpoint (SUR): Blood pressure
Study 38902747 — Predictive Biomarker (PRD): ALOX12 mRNA
Genes: ALOX12; 12LO; LOG12
Study 38902747 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 38902747 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study 38902747 — Predictive Biomarker (PRD): ALOX15 mRNA
Genes: ALOX15; LOG15
Study 38902747 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 38902840 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 38902846 — Surrogate Endpoint (SUR): Blood pressure
Study 38902860 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study 38903523 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 38904251 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 38904251 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 38904251 — Predictive Biomarker (PRD): SERPINA4 mRNA
Genes: SERPINA4; KST; PI4
Study 38904251 — Predictive Biomarker (PRD): SVEP1 mRNA
Genes: SVEP1; C9orf13; CCP22; SELOB
Study 38904646 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 38904918 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38904918 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 38905635 — Predictive Biomarker (PRD): MEIS1 mRNA
Genes: MEIS1
Study 38905635 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 38906440 — Monitoring Biomarker (MOI): HBV DNA
Study 38906970 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38907104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38907106 — Surrogate Endpoint (SUR): Blood pressure
Study 38907138 — Predictive Biomarker (PRD): FANCA mRNA
Genes: FANCA; FAA; FACA; FANCH
Study 38907138 — Predictive Biomarker (PRD): FANCI mRNA
Genes: FANCI; KIAA1794
Study 38907160 — Safety Biomarker (SAF): Interleukin 1
Study 38907310 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 38907310 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 38907342 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 38907380 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 38909229 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38909671 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 38910002 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 38912228 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38912296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38912296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38912654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38912654 — Surrogate Endpoint (SUR): Blood pressure
Study 38912784 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 38912905 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 38912927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38913003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38913004 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 38913710 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38913881 — Surrogate Endpoint (SUR): Pathological complete response
Study 38913933 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 38913933 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 38913933 — Predictive Biomarker (PRD): Hormone receptor
Study 38913962 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study 38914124 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 38914224 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 38914294 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38914959 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 38914959 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 38914959 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 38915065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38915423 — Predictive Biomarker (PRD): LAMA2 mRNA
Genes: LAMA2; LAMM
Study 38915796 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 38915796 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 38916429 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 38916717 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 38916717 — Surrogate Endpoint (SUR): Blood pressure
Study 38916753 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 38917111 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 38917366 — Predictive Biomarker (PRD): REL mRNA
Genes: REL
Study 38917525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 38917525 — Predictive Biomarker (PRD): TP53INP1 mRNA
Genes: TP53INP1; P53DINP1; SIP
Study 38917525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 38917696 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 38918556 — Surrogate Endpoint (SUR): Pathological complete response
Study 38918871 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study 38918871 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study 38918903 — Surrogate Endpoint (SUR): Blood pressure
Study 38919522 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 38919799 — Predictive Biomarker (PRD): SP4 mRNA
Genes: SP4
Study 38920407 — Predictive Biomarker (PRD): WEE1 mRNA
Genes: WEE1
Study 38920618 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 38922307 — Predictive Biomarker (PRD): STING1 mRNA
Genes: STING1; ERIS; MITA; STING; TMEM173
Study 38922488 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol