TrialPanorama/TrialPanorama-database huggingface dataset:
Study 37062298 — Predictive Biomarker (PRD): NR4A3 mRNA
Genes: NR4A3; CHN; CSMF; MINOR; NOR1; TEC
Study 37062500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37062581 — Predictive Biomarker (PRD): OSR1 mRNA
Genes: OSR1; ODD
Study 37063316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 37063904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37063904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37063916 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37064032 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 37064508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37064508 — Surrogate Endpoint (SUR): Blood pressure
Study 37064508 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37066249 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 37066828 — Safety Biomarker (SAF): Hyaluronic acid
Study 37067525 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 37067525 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 37067525 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 37067554 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 37067675 — Safety Biomarker (SAF): Human leucocyte antigen
Study 37067675 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 37067675 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 37067675 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study 37067785 — Surrogate Endpoint (SUR): Blood pressure
Study 37067952 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 37068504 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study 37068504 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37068528 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 37068906 — Predictive Biomarker (PRD): TSTD1 mRNA
Genes: TSTD1; KAT
Study 37069359 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 37069359 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 37069364 — Surrogate Endpoint (SUR): Serum uric acid
Study 37069472 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 37069527 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 37069527 — Surrogate Endpoint (SUR): Serum calcium
Study 37069531 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 37070436 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37070653 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 37070653 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 37071035 — Predictive Biomarker (PRD): IDE mRNA
Genes: IDE
Study 37071035 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 37071094 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37071094 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 37071094 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 37071166 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 37071469 — Safety Biomarker (SAF): Hyaluronic acid
Study 37071836 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 37072349 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37072421 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 37072421 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 37072512 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37072571 — Predictive Biomarker (PRD): POU5F1 mRNA
Genes: POU5F1; OCT3; OCT4; OTF3
Study 37072571 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 37072577 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37073174 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 37073741 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 37073882 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 37074202 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37074522 — Surrogate Endpoint (SUR): Blood pressure
Study 37074571 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 37074571 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 37074571 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 37074705 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 37075127 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 37075301 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37075617 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37077733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37077916 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 37077916 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 37077916 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 37078412 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 37078412 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 37078706 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 37079365 — Surrogate Endpoint (SUR): Blood pressure
Study 37079385 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 37079385 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 37079385 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 37079385 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 37079385 — Predictive Biomarker (PRD): RELT mRNA
Genes: RELT; TNFRSF19L
Study 37079385 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 37079385 — Predictive Biomarker (PRD): COL6A3 mRNA
Genes: COL6A3
Study 37079385 — Predictive Biomarker (PRD): EDA2R mRNA
Genes: EDA2R; TNFRSF27; XEDAR; UNQ2448/PRO5727/PRO34080
Study 37079385 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37079385 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 37079518 — Predictive Biomarker (PRD): CIDEC mRNA
Genes: CIDEC; FSP27
Study 37079518 — Predictive Biomarker (PRD): PLIN1 mRNA
Genes: PLIN1; PERI; PLIN
Study 37079518 — Predictive Biomarker (PRD): RAB8A mRNA
Genes: RAB8A; MEL; RAB8
Study 37079518 — Predictive Biomarker (PRD): TBC1D4 mRNA
Genes: TBC1D4; AS160; KIAA0603
Study 37079569 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37079726 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 37079726 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 37080222 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 37080629 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37081029 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37081046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37081426 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37081523 — Monitoring Biomarker (MOI): Cell-free DNA
Study 37081574 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 37081617 — Surrogate Endpoint (SUR): Serum creatinine
Study 37081617 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 37081722 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37082935 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 37083300 — Predictive Biomarker (PRD): BMX mRNA
Genes: BMX
Study 37083360 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 37084401 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 37085674 — Predictive Biomarker (PRD): GSTA1 mRNA
Genes: GSTA1
Study 37085849 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 37085862 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 37086083 — Surrogate Endpoint (SUR): Blood pressure
Study 37086340 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 37086340 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 37086568 — Predictive Biomarker (PRD): CLN3 mRNA
Genes: CLN3; BTS
Study 37086614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37086745 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37087459 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37087470 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 37087950 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 37088310 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 37088311 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 37088447 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 37088447 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 37089863 — Predictive Biomarker (PRD): Leucine-rich alpha-2-glycoprotein
Genes: LRG1; LRG
Study 37090089 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37090440 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37092287 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 37093072 — Predictive Biomarker (PRD): SYNE1 mRNA
Genes: SYNE1; C6orf98; KIAA0796; KIAA1262; KIAA1756; MYNE1
Study 37093072 — Predictive Biomarker (PRD): RYR2 mRNA
Genes: RYR2
Study 37093072 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37093072 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 37093074 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 37093074 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 37093074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37093160 — Surrogate Endpoint (SUR): Blood pressure
Study 37093350 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study 37093350 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 37093712 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 37094336 — Surrogate Endpoint (SUR): Blood pressure
Study 37094988 — Predictive Biomarker (PRD): Microsatellite instability
Study 37094998 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 37094998 — Predictive Biomarker (PRD): SPIN1 mRNA
Genes: SPIN1; OCR; SPIN
Study 37094998 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37095120 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 37095120 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 37095250 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37095298 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 37095378 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37095637 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 37095689 — Surrogate Endpoint (SUR): Blood pressure
Study 37096015 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 37096015 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 37096188 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 37096236 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 37097894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37099132 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study 37099283 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37099299 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 37099511 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 37099733 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 37099733 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 37099733 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 37099736 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 37099777 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 37100060 — Predictive Biomarker (PRD): IL6ST mRNA
Genes: IL6ST
Study 37100060 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37100187 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 37100205 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 37100536 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 37100705 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 37100821 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 37101768 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 37101768 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 37102010 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 37102392 — Safety Biomarker (SAF): miR-181a
Study 37102399 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 37103493 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 37103493 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 37103532 — Surrogate Endpoint (SUR): Bone mineral density
Study 37103592 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 37103592 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 37103658 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 37104758 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37104758 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 37104944 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37105234 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 37105265 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 37105265 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 37105265 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 37105304 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37105511 — Surrogate Endpoint (SUR): Serum creatinine
Study 37105694 — Surrogate Endpoint (SUR): Blood pressure
Study 37106164 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 37106321 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37106374 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 37107208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37107903 — Surrogate Endpoint (SUR): Blood pressure
Study 37108484 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study 37109179 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 37109303 — Surrogate Endpoint (SUR): Serum creatinine
Study 37109468 — Predictive Biomarker (PRD): DDN mRNA
Genes: DDN; KIAA0749
Study 37111382 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37114393 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 37114393 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 37115132 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37115135 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 37115337 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 37115359 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 37115359 — Surrogate Endpoint (SUR): Forced vital capacity
Study 37115514 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 37115658 — Surrogate Endpoint (SUR): Blood pressure
Study 37115807 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 37115807 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 37115908 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 37115908 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 37115976 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37116523 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 37116523 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 37116605 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37116644 — Surrogate Endpoint (SUR): Blood pressure
Study 37117001 — Surrogate Endpoint (SUR): Blood pressure
Study 37117153 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 37117201 — Surrogate Endpoint (SUR): Serum creatinine
Study 37117993 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37118803 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37119051 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 37119080 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 37119264 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 37119314 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 37119314 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 37119480 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 37119510 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 37119523 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37119829 — Predictive Biomarker (PRD): DKK3 mRNA
Genes: DKK3; REIC; UNQ258/PRO295
Study 37119868 — Surrogate Endpoint (SUR): Blood pressure
Study 37119871 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 37120136 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 37120522 — Predictive Biomarker (PRD): CNTN4 mRNA
Genes: CNTN4
Study 37120522 — Predictive Biomarker (PRD): PRLHR mRNA
Genes: PRLHR; GPR10; GR3
Study 37120600 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 37120600 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 37120736 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37121865 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 37122357 — Monitoring Biomarker (MOI): HBV DNA
Study 37123045 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37123046 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 37123046 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 37123046 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 37123046 — Predictive Biomarker (PRD): TPH2 mRNA
Genes: TPH2; NTPH
Study 37123046 — Predictive Biomarker (PRD): TDO2 mRNA
Genes: TDO2; TDO
Study 37123046 — Predictive Biomarker (PRD): SLC7A5 mRNA
Genes: SLC7A5; CD98LC; LAT1; MPE16
Study 37124732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37124732 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 37124732 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37125046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37125529 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37126021 — Predictive Biomarker (PRD): Microsatellite instability
Study 37126399 — Surrogate Endpoint (SUR): Serum testosterone
Study 37126599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37126599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37126739 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 37127045 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37127523 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37127526 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 37127632 — Predictive Biomarker (PRD): ERVMER34-1 mRNA
Genes: ERVMER34-1; HEMO; LP9056
Study 37127683 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 37127754 — Predictive Biomarker (PRD): PANK3 mRNA
Genes: PANK3
Study 37127754 — Predictive Biomarker (PRD): PANK4 mRNA
Genes: PANK4
Study 37127754 — Predictive Biomarker (PRD): SLC5A6 mRNA
Genes: SLC5A6; SMVT
Study 37128727 — Safety Biomarker (SAF): IL-6 and IL-10
Study 37129153 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 37129155 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 37129197 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37130682 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 37130685 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37130827 — Surrogate Endpoint (SUR): Blood pressure