TrialPanorama/TrialPanorama-database huggingface dataset:
Study 34186056 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study 34186056 — Surrogate Endpoint (SUR): Total kidney volume
Study 32031757 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 34131048 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 32244296 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study 32244296 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 32244296 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 32915892 — Surrogate Endpoint (SUR): Blood pressure
Study 36101515 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 36101515 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35871950 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35861301 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 35861301 — Surrogate Endpoint (SUR): Serum creatinine
Study 33964852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35837181 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33367965 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32622603 — Predictive Biomarker (PRD): MCTS1 mRNA
Genes: MCTS1; MCT1
Study 32622603 — Predictive Biomarker (PRD): FFAR2 mRNA
Genes: FFAR2; FFA2; GPCR43; GPR43
Study 32622603 — Predictive Biomarker (PRD): AQP3 mRNA
Genes: AQP3
Study 32622603 — Predictive Biomarker (PRD): SLC15A1 mRNA
Genes: SLC15A1; PEPT1
Study 32622603 — Predictive Biomarker (PRD): SLC15A2 mRNA
Genes: SLC15A2; PEPT2
Study 32622603 — Predictive Biomarker (PRD): SLC1A1 mRNA
Genes: SLC1A1; EAAC1; EAAT3; HEAAC1
Study 32430375 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 32552433 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 35245661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35245661 — Surrogate Endpoint (SUR): Serum uric acid
Study 34139038 — Surrogate Endpoint (SUR): Blood pressure
Study 32039871 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32039871 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 34351721 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33105946 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 33622326 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 32847912 — Surrogate Endpoint (SUR): Blood pressure
Study 32314053 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35945827 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 35945827 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 34518313 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 32819292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32381160 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32381160 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33881579 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 34842984 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33417284 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 32860716 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 33440207 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33440207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33440207 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 36113378 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32946459 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33904045 — Surrogate Endpoint (SUR): Blood pressure
Study 35951060 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 35951060 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33722420 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 33722420 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 36310622 — Surrogate Endpoint (SUR): Blood pressure
Study 32059021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34472755 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 32690147 — Surrogate Endpoint (SUR): Blood pressure
Study 33245746 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 32520346 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 32520346 — Surrogate Endpoint (SUR): Blood pressure
Study 35389487 — Surrogate Endpoint (SUR): Blood pressure
Study 34067389 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 34067389 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32703779 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36343758 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 36151016 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35557247 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 33957713 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34462030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34462030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34462030 — Safety Biomarker (SAF): BDNF
Study 34462030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33492637 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32517477 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 32517477 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 33971993 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36129233 — Safety Biomarker (SAF): Hyaluronic acid
Study 36103665 — Safety Biomarker (SAF): Hyaluronic acid
Study 32379673 — Surrogate Endpoint (SUR): Blood pressure
Study 36752479 — Surrogate Endpoint (SUR): Blood pressure
Study 33642340 — Surrogate Endpoint (SUR): Blood pressure
Study 32580979 — Predictive Biomarker (PRD): TICAM2 mRNA
Genes: TICAM2; TIRAP3; TIRP; TRAM
Study 35439293 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35847015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35182721 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35182721 — Surrogate Endpoint (SUR): Pathological complete response
Study 32861716 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 34585595 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 32722454 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32457004 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 33940082 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 35371949 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 33562090 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36099688 — Predictive Biomarker (PRD): ST8SIA4 mRNA
Genes: ST8SIA4; PST; PST1; SIAT8D
Study 32846929 — Predictive Biomarker (PRD): miR-25
Genes: MIR25
Study 32846929 — Predictive Biomarker (PRD): miR-31
Genes: MIR31
Study 34428440 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34428440 — Surrogate Endpoint (SUR): Blood pressure
Study 32609422 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 32609422 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 35637272 — Safety Biomarker (SAF): DRD2
Study 34653245 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 34653245 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 34261354 — Predictive Biomarker (PRD): GAPDH mRNA
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 34261354 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 34261354 — Predictive Biomarker (PRD): GDF1 mRNA
Genes: GDF1
Study 36170749 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33277990 — Surrogate Endpoint (SUR): Blood pressure
Study 32148330 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 35387672 — Surrogate Endpoint (SUR): Blood pressure
Study 35387672 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32959589 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 32959589 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33590850 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32476183 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32476183 — Predictive Biomarker (PRD): Hormone receptor
Study 34436536 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34436536 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34436536 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34436536 — Predictive Biomarker (PRD): Hormone receptor
Study 32174352 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33811367 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 34126630 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32576084 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 32576084 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32576084 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32576084 — Predictive Biomarker (PRD): Hormone receptor
Study 33727798 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 36300646 — Monitoring Biomarker (MOI): HBV DNA
Study 32657611 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 33675704 — Safety Biomarker (SAF): Hyaluronic acid
Study 34936957 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 34936957 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34936957 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 34936957 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34936957 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 32567439 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32567439 — Surrogate Endpoint (SUR): Blood pressure
Study 32567439 — Surrogate Endpoint (SUR): Serum uric acid
Study 33647171 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 34561695 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 34561695 — Surrogate Endpoint (SUR): Blood pressure
Study 33186704 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 33186704 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36372680 — Safety Biomarker (SAF): Hyaluronic acid
Study 33346141 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 32615663 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 35351696 — Surrogate Endpoint (SUR): Blood pressure
Study 34274784 — Surrogate Endpoint (SUR): Blood pressure
Study 32459322 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 32020706 — Surrogate Endpoint (SUR): Blood pressure
Study 36368262 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 36368262 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 36368262 — Predictive Biomarker (PRD): PCSK1 mRNA
Genes: PCSK1; NEC1
Study 36368262 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34407579 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 34407579 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 34980260 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 34980260 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 33499913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34538333 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33274683 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 35678643 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 35678643 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35496038 — Surrogate Endpoint (SUR): Blood pressure
Study 33172240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 32871910 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 34611052 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 33648441 — Surrogate Endpoint (SUR): Blood pressure
Study 32819465 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 33347667 — Safety Biomarker (SAF): Interleukin 1
Study 34049101 — Predictive Biomarker (PRD): GRIK1 mRNA
Genes: GRIK1; GLUR5
Study 35671774 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35671774 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 35671774 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 35671774 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 32907989 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 32907989 — Surrogate Endpoint (SUR): Blood pressure
Study 32111307 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32111307 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32111307 — Safety Biomarker (SAF): Interleukin 1
Study 32111307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32111307 — Predictive Biomarker (PRD): OCLN mRNA
Genes: OCLN
Study 32111307 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study 35769693 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 34742318 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33714257 — Predictive Biomarker (PRD): ARRDC1 mRNA
Genes: ARRDC1
Study 33714257 — Predictive Biomarker (PRD): NCK1 mRNA
Genes: NCK1; NCK
Study 32084251 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32976626 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34773474 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34773474 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 34773474 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 34773474 — Predictive Biomarker (PRD): TBK1 mRNA
Genes: TBK1; NAK
Study 34773474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36374913 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 33662589 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 33915217 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 33915217 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 33624254 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study 35704597 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 35704597 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 35704597 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 34373322 — Surrogate Endpoint (SUR): Serum sodium
Study 36288782 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 36381249 — Surrogate Endpoint (SUR): Bone mineral density
Study 34852379 — Predictive Biomarker (PRD): F2RL3 mRNA
Genes: F2RL3; PAR4
Study 35140880 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 35524376 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 35524376 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 35970102 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33399376 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 33399376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36082065 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 35688920 — Surrogate Endpoint (SUR): Blood pressure
Study 34981778 — Safety Biomarker (SAF): HLA-DQA1
Genes: CELIAC1
Study 32666822 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 33073963 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33073963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33073963 — Surrogate Endpoint (SUR): Blood pressure
Study 33073963 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33073963 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33073963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32035020 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 32035020 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 33798304 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 35980949 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35980949 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35980949 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35980949 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 35980949 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 35980949 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 35980949 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 33567047 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 33567047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33567047 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 35544074 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33407263 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 34672147 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34672147 — Surrogate Endpoint (SUR): Blood pressure
Study 36128636 — Monitoring Biomarker (MOI): HBV DNA
Study 34129025 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32859388 — Safety Biomarker (SAF): Vascular endothelial cadherin
Genes: CDH5
Study 32594915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32594915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35371278 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 35371278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35371278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35371278 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 35371278 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 35371278 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 33509762 — Surrogate Endpoint (SUR): Blood pressure
Study 36014837 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 36014837 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 36014837 — Surrogate Endpoint (SUR): Blood pressure
Study 36014837 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 36014837 — Surrogate Endpoint (SUR): Serum calcium
Study 33545548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33545548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33545548 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 33545548 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32888370 — Surrogate Endpoint (SUR): Blood pressure
Study 32888370 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32888370 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34159704 — Surrogate Endpoint (SUR): Bone mineral density
Study 32538747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 616606737 — Surrogate Endpoint (SUR): Blood pressure
Study 32280092 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 36120764 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 35183882 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35183882 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35183882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33719920 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33719920 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35607946 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 32700572 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol