TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35272897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35312749 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35312749 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 36447221 — Surrogate Endpoint (SUR): Serum creatinine
Study 33539946 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33539946 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35403245 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35403245 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33237904 — Surrogate Endpoint (SUR): Blood pressure
Study 35490579 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35809704 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 32535732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33903656 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 33903656 — Surrogate Endpoint (SUR): Blood pressure
Study 34406341 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 32805013 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 36437222 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 34119535 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 34119535 — Predictive Biomarker (PRD): DRAM1 mRNA
Genes: DRAM1; DRAM
Study 34119535 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32521132 — Surrogate Endpoint (SUR): Serum creatinine
Study 35175249 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34845313 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 34845313 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 34721612 — Predictive Biomarker (PRD): SLC26A3 mRNA
Genes: SLC26A3; DRA
Study 35453051 — Predictive Biomarker (PRD): DDT mRNA
Genes: DDT
Study 32816944 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 37142462 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33606270 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 33838224 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33838224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34259401 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 32255785 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 35237033 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35237033 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32839843 — Surrogate Endpoint (SUR): Bone mineral density
Study 33609973 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36145126 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 32275025 — Surrogate Endpoint (SUR): Blood pressure
Study 33848462 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 33848462 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 33677935 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36470985 — Safety Biomarker (SAF): Hyaluronic acid
Study 33547949 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 33547949 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 35101644 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 33814235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33814235 — Surrogate Endpoint (SUR): Serum triglycerides
Study 33415866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33415866 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33415866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33670720 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33593702 — Surrogate Endpoint (SUR): Pathological complete response
Study 32609075 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 32609075 — Predictive Biomarker (PRD): MMEL1 mRNA
Genes: MMEL1; MELL1; MMEL2; NEP2
Study 33039944 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 36480788 — Surrogate Endpoint (SUR): Blood pressure
Study 32651955 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 36203226 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33896823 — Safety Biomarker (SAF): miR-142
Genes: MIR142
Study 33896823 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study 33523582 — Safety Biomarker (SAF): Hyaluronic acid
Study 33964853 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 33964853 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 33964853 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 33964853 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 32354795 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 32354795 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33450885 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 33450885 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35379633 — Predictive Biomarker (PRD): RAPH1 mRNA
Genes: RAPH1; ALS2CR18; ALS2CR9; KIAA1681; LPD; PREL2; RMO1
Study 32434291 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32434291 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 32434291 — Surrogate Endpoint (SUR): Blood pressure
Study 33423986 — Predictive Biomarker (PRD): TXN mRNA
Genes: TXN; TRDX; TRX; TRX1
Study 34520052 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 33204004 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33204004 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 35551628 — Monitoring Biomarker (MOI): Procalcitonin
Study 35551628 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 32213019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33063157 — Surrogate Endpoint (SUR): Blood pressure
Study 35725616 — Predictive Biomarker (PRD): PITX2 mRNA
Genes: PITX2; ARP1; RGS; RIEG; RIEG1
Study 33741648 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 32631301 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32631301 — Surrogate Endpoint (SUR): Blood pressure
Study 33917778 — Surrogate Endpoint (SUR): Blood pressure
Study 34872271 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 36400384 — Surrogate Endpoint (SUR): Pathological complete response
Study 36368427 — Surrogate Endpoint (SUR): Blood pressure
Study 32321551 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32588134 — Surrogate Endpoint (SUR): Blood pressure
Study 34108184 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34108184 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 34108184 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 34108184 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 32629682 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 32209621 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 32103747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32234534 — Surrogate Endpoint (SUR): Blood pressure
Study 35017325 — Surrogate Endpoint (SUR): Serum creatinine
Study 33249630 — Monitoring Biomarker (MOI): HBV DNA
Study 36009012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33337110 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 35312440 — Surrogate Endpoint (SUR): Blood pressure
Study 35771346 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36326418 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32005582 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 33436922 — Predictive Biomarker (PRD): SVOP mRNA
Genes: SVOP
Study 34479543 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32350180 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 32350180 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 32513581 — Surrogate Endpoint (SUR): Serum triglycerides
Study 32513581 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32513581 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32559353 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 33745724 — Predictive Biomarker (PRD): MEST mRNA
Genes: MEST; PEG1
Study 32830894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36423444 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 35368921 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 33207670 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34560141 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 32119742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33784735 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34332629 — Surrogate Endpoint (SUR): Blood pressure
Study 36201360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33559410 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35236281 — Monitoring Biomarker (MOI): Procalcitonin
Study 35618342 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35618342 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34034365 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 32033610 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 34810107 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 35030278 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 34987204 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 33092420 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 33246252 — Surrogate Endpoint (SUR): Serum sodium
Study 32803720 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 32827441 — Surrogate Endpoint (SUR): Bone mineral density
Study 33611087 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32694343 — Surrogate Endpoint (SUR): Blood pressure
Study 32694343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32694343 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 34930689 — Surrogate Endpoint (SUR): Blood pressure
Study 37614053 — Surrogate Endpoint (SUR): Blood pressure
Study 34508839 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 33749798 — Safety Biomarker (SAF): Hyaluronic acid
Study 33739461 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32124925 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33600287 — Surrogate Endpoint (SUR): Blood pressure
Study 32152169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34714194 — Surrogate Endpoint (SUR): Serum uric acid
Study 34714194 — Surrogate Endpoint (SUR): Blood pressure
Study 34261489 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34261489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34261489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35075079 — Surrogate Endpoint (SUR): Blood pressure
Study 34627673 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 32087750 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 32242394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32242394 — Surrogate Endpoint (SUR): Bone mineral density
Study 36279299 — Surrogate Endpoint (SUR): Blood pressure
Study 33829984 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 36082521 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33270032 — Surrogate Endpoint (SUR): Blood pressure
Study 34258627 — Surrogate Endpoint (SUR): Blood pressure
Study 34258627 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 32193044 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36164077 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 36164077 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 36164077 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 36164077 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 33024322 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 32681091 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32681091 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35769842 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 35769842 — Surrogate Endpoint (SUR): Serum creatinine
Study 34774885 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 34774885 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 34774885 — Safety Biomarker (SAF): Reactive oxygen species
Study 35243362 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 35243362 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 34621380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34621380 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 34621380 — Safety Biomarker (SAF): Interleukin 1
Study 34621380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33526271 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34156881 — Surrogate Endpoint (SUR): Sperm parameters
Study 33038280 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 35142643 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 34444121 — Surrogate Endpoint (SUR): Probing pocket depth
Study 36151343 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 34231290 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 33583304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33125189 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32166864 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 32166864 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 33907787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33907787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34981428 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 35120890 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 35120890 — Predictive Biomarker (PRD): IL18R1 mRNA
Genes: IL18R1; IL1RRP
Study 35120890 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 35708845 — Surrogate Endpoint (SUR): Blood pressure
Study 35051725 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35051725 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 36101997 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36101997 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 36101997 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 36101997 — Safety Biomarker (SAF): BDNF
Study 36101997 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36101997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33884889 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 33884889 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36058687 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 35599469 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 34210824 — Surrogate Endpoint (SUR): Blood pressure
Study 33057184 — Surrogate Endpoint (SUR): Blood pressure
Study 32826786 — Predictive Biomarker (PRD): DEGS1 mRNA
Genes: DEGS1; DES1; MLD; MIG15
Study 32434296 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 33342941 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33734288 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 33813324 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 35770887 — Surrogate Endpoint (SUR): Blood pressure
Study 32604068 — Surrogate Endpoint (SUR): Bone mineral density
Study 34009514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 616666876 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 32964986 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 32964986 — Predictive Biomarker (PRD): ATF6 mRNA
Genes: ATF6
Study 32964986 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 32964986 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 32964986 — Safety Biomarker (SAF): Netrin-1
Genes: NTN1; NTN1L
Study 34310978 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 35686334 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 32720602 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32202256 — Surrogate Endpoint (SUR): Blood pressure
Study 36031718 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 32337700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32876468 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 34867233 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33434080 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 35788492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35788492 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 32412597 — Surrogate Endpoint (SUR): Blood pressure
Study 35503446 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 32607749 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 32607749 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 33414824 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 35222903 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35222903 — Surrogate Endpoint (SUR): Serum triglycerides
Study 32085929 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34863332 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34863332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36181074 — Monitoring Biomarker (MOI): HBV DNA
Study 33306556 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34289879 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35691283 — Surrogate Endpoint (SUR): Blood pressure
Study 32048768 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 32048768 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33761873 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study 32221554 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32445558 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 33622114 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 33622114 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33622114 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33622114 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 33622114 — Predictive Biomarker (PRD): Hormone receptor
Study 34762527 — Surrogate Endpoint (SUR): Blood pressure
Study 34267066 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 33668012 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 32057546 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 34456582 — Predictive Biomarker (PRD): BMP4 mRNA
Genes: BMP4; BMP2B; DVR4
Study 34456582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32455853 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 34458670 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 35856838 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 35442343 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 34111674 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34111674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2