TrialPanorama/TrialPanorama-database huggingface dataset:
Study 39522641 — Predictive Biomarker (PRD): Hormone receptor
Study 39522641 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 39523406 — Surrogate Endpoint (SUR): Blood pressure
Study 39523406 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 39523878 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 39525672 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 39525677 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 39525874 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 39525874 — Safety Biomarker (SAF): BDNF
Study 39525887 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 39526078 — Predictive Biomarker (PRD): MBTPS1 mRNA
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 39526855 — Surrogate Endpoint (SUR): Blood pressure
Study 39526855 — Surrogate Endpoint (SUR): Serum calcium
Study 39527056 — Surrogate Endpoint (SUR): Bone mineral density
Study 39527097 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39527097 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 39527097 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 39527236 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 39527236 — Surrogate Endpoint (SUR): Forced vital capacity
Study 39528489 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 39528916 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 39529054 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 39529054 — Predictive Biomarker (PRD): PRX mRNA
Genes: PRX; KIAA1620
Study 39529169 — Predictive Biomarker (PRD): Microsatellite instability
Study 39530130 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 39530262 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 39530558 — Predictive Biomarker (PRD): Microsatellite instability
Study 39530558 — Monitoring Biomarker (MOI): Cell-free DNA
Study 39530627 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study 39531369 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 39531903 — Predictive Biomarker (PRD): Microsatellite instability
Study 39532185 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 39532238 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 39532835 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 39532861 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 39533015 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 39533015 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 39533186 — Surrogate Endpoint (SUR): Blood pressure
Study 39533194 — Surrogate Endpoint (SUR): Blood pressure
Study 39533204 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 39533349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 39533349 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 39533412 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 39534481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 39534593 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 39534856 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 39535306 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 39536433 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39536433 — Predictive Biomarker (PRD): Hormone receptor
Study 39536455 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 39536455 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 39536691 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 39536847 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 39536847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39537191 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 39537385 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 39537648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 39538139 — Surrogate Endpoint (SUR): Blood pressure
Study 39538139 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 39540799 — Monitoring Biomarker (MOI): HBV DNA
Study 39541094 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 39541169 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 39541169 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 39541202 — Predictive Biomarker (PRD): KMT2D mRNA
Genes: KMT2D; ALR; MLL2; MLL4
Study 39541202 — Predictive Biomarker (PRD): COL4A4 mRNA
Genes: COL4A4
Study 39541202 — Predictive Biomarker (PRD): CTNNA2 mRNA
Genes: CTNNA2; CAPR
Study 39541202 — Predictive Biomarker (PRD): SCN4A mRNA
Genes: SCN4A
Study 39541377 — Predictive Biomarker (PRD): SDHA mRNA
Genes: SDHA; SDH2; SDHF
Study 39541377 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 39541377 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 39541377 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study 39541993 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 39542642 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 39542655 — Predictive Biomarker (PRD): CKM mRNA
Genes: CKM; CKMM
Study 39542655 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 39542655 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 39543304 — Surrogate Endpoint (SUR): Blood pressure
Study 39543527 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 39543578 — Surrogate Endpoint (SUR): Probing pocket depth
Study 39544897 — Surrogate Endpoint (SUR): Forced vital capacity
Study 39544899 — Surrogate Endpoint (SUR): Forced vital capacity
Study 39545451 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 39546040 — Surrogate Endpoint (SUR): Blood pressure
Study 39546129 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 39546748 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 39546748 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 39546931 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study 39546931 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 39546957 — Surrogate Endpoint (SUR): Blood pressure
Study 39547230 — Predictive Biomarker (PRD): ARSB mRNA
Genes: ARSB
Study 39547694 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39548016 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 39548016 — Surrogate Endpoint (SUR): Blood pressure
Study 39548306 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 39548306 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 39548414 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 39548414 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39548423 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 39548423 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 39548560 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 39549554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 39549554 — Safety Biomarker (SAF): Reactive oxygen species
Study 39549678 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 39549678 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 39549719 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 39549719 — Predictive Biomarker (PRD): PCSK1 mRNA
Genes: PCSK1; NEC1
Study 39549719 — Predictive Biomarker (PRD): LEPROT mRNA
Genes: LEPROT; LEPR; OBR
Study 39549817 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 39550530 — Surrogate Endpoint (SUR): Blood pressure
Study 39550716 — Surrogate Endpoint (SUR): Serum potassium
Study 39551007 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 39551040 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 39551040 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39551040 — Predictive Biomarker (PRD): LRIT1 mRNA
Genes: LRIT1; LRRC21; PAL
Study 39551093 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 39551167 — Surrogate Endpoint (SUR): Blood pressure
Study 39551469 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 39551469 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 39551469 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 39551470 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 39551581 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 39551600 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 39551600 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 39551791 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 39551891 — Surrogate Endpoint (SUR): Blood pressure
Study 39551891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39554793 — Predictive Biomarker (PRD): ALDH1A1 mRNA
Genes: ALDH1A1; ALDC; ALDH1; PUMB1
Study 39554793 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 39555818 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 39555823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39555827 — Surrogate Endpoint (SUR): Blood pressure
Study 39555828 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 39555828 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 39556016 — Predictive Biomarker (PRD): LAMP2 mRNA
Genes: LAMP2
Study 39556016 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 39556016 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 39556389 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 39556768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39557058 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39560075 — Surrogate Endpoint (SUR): Bone mineral density
Study 39560398 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 39561184 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 39561225 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 39561281 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 39561359 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 39561689 — Surrogate Endpoint (SUR): Blood pressure
Study 39561689 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 39562048 — Predictive Biomarker (PRD): miR-106b
Genes: MIR106B
Study 39562048 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study 39562048 — Safety Biomarker (SAF): miR-15a
Genes: MIR15A
Study 39562048 — Safety Biomarker (SAF): miR-18a
Genes: MIR18A
Study 39562048 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 39562048 — Predictive Biomarker (PRD): miR-93
Genes: MIR93
Study 39562502 — Predictive Biomarker (PRD): FANCA mRNA
Genes: FANCA; FAA; FACA; FANCH
Study 39562502 — Predictive Biomarker (PRD): FANCD2 mRNA
Genes: FANCD2; FACD
Study 39563035 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 39563035 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 39563094 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 39563102 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 39563248 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 39563319 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 39563886 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 39563886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 39565276 — Surrogate Endpoint (SUR): Forced vital capacity
Study 39565449 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 39565495 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39565495 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 39565905 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 39566404 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 39566467 — Predictive Biomarker (PRD): TP63 mRNA
Genes: TP63; KET; P63; P73H; P73L; TP73L
Study 39566600 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 39567210 — Predictive Biomarker (PRD): LILRB2 mRNA
Genes: LILRB2; ILT4; LIR2; MIR10
Study 39567211 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 39568009 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 39568724 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 39568724 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 39568724 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 39568724 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 39569196 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 39570031 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 39570213 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 39570398 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 39570545 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 39570590 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 39570620 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 39571113 — Surrogate Endpoint (SUR): Blood pressure
Study 39571171 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 39571171 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 39571171 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 39571342 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 39571744 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 39572264 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 39572264 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 39572264 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 39572264 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 39572264 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 39572264 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 39572681 — Predictive Biomarker (PRD): ANXA2 mRNA
Genes: ANXA2; ANX2; ANX2L4; CAL1H; LPC2D
Study 39572739 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 39572763 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 39572763 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 39574155 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 39574505 — Predictive Biomarker (PRD): MXD1 mRNA
Genes: MXD1; MAD
Study 39574523 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 39575028 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 39575188 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 39575188 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 39575565 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 39575565 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 39575727 — Surrogate Endpoint (SUR): Blood pressure
Study 39575854 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 39576675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 39576683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39576798 — Surrogate Endpoint (SUR): Blood pressure
Study 39577214 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 39577214 — Surrogate Endpoint (SUR): Blood pressure
Study 39577511 — Monitoring Biomarker (MOI): Cell-free DNA
Study 39577691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 39577708 — Surrogate Endpoint (SUR): Serum triglycerides
Study 39577867 — Predictive Biomarker (PRD): NR2E1 mRNA
Genes: NR2E1; TLX
Study 39577975 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 39578309 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 39578347 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 39578778 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 39578778 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 39578819 — Surrogate Endpoint (SUR): Probing pocket depth
Study 39578819 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 39579274 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 39580145 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 39580145 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 39580437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39580468 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 39580468 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 39580601 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 39580622 — Predictive Biomarker (PRD): RARB mRNA
Genes: RARB; HAP; NR1B2
Study 39580622 — Predictive Biomarker (PRD): LRP1B mRNA
Genes: LRP1B; LRPDIT
Study 39580793 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 39581180 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 39581330 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 39581380 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 39581380 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 39581887 — Surrogate Endpoint (SUR): Probing pocket depth
Study 39581892 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 39581892 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39581892 — Predictive Biomarker (PRD): Hormone receptor
Study 39582029 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 39582544 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 39582666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 39582898 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39583653 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 39583952 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 39583952 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 39583953 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 39583953 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 39584380 — Predictive Biomarker (PRD): C12orf57 mRNA
Genes: C12orf57; C10
Study 39584464 — Surrogate Endpoint (SUR): Probing pocket depth
Study 39584557 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 39585339 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 39585668 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 39586038 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 39586304 — Predictive Biomarker (PRD): MBTPS1 mRNA
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 39586616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39587050 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39587050 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 39587050 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 39587593 — Surrogate Endpoint (SUR): Probing pocket depth
Study 39587600 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 39587796 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 39587825 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 39587825 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 39587931 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 39588131 — Surrogate Endpoint (SUR): Bone mineral density
Study 39589133 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 39589559 — Surrogate Endpoint (SUR): Blood pressure
Study 39589664 — Surrogate Endpoint (SUR): Bone mineral density
Study 39589666 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 39589690 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study 39589690 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 39589719 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 39591972 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 39591972 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study 39591972 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study 39591972 — Predictive Biomarker (PRD): Hepatitis A virus cellular receptor 2
Genes: HAVCR2; TIM3; TIMD3
Study 39592501 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 39592624 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39592624 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 39592624 — Predictive Biomarker (PRD): Hormone receptor
Study 39592626 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 39592626 — Safety Biomarker (SAF): Th2 cell
Study 39592888 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 39592888 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 39593091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39593435 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT