TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33327246 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 33327246 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 32525048 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 33453076 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 33453076 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 36047511 — Surrogate Endpoint (SUR): Serum testosterone
Study 32078063 — Surrogate Endpoint (SUR): Serum uric acid
Study 35023349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36293916 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 33988943 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 33988943 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 32487035 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34798841 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32295491 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35549736 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36058429 — Surrogate Endpoint (SUR): Complete renal response
Study 35839116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35839116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34995105 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 34995105 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34995105 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34995105 — Predictive Biomarker (PRD): Hormone receptor
Study 34995105 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32647965 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 34114720 — Surrogate Endpoint (SUR): Blood pressure
Study 34114720 — Surrogate Endpoint (SUR): Serum sodium
Study 34114720 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34680134 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 34680134 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 34954044 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33884713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32464532 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32464532 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 32464532 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 32464532 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 32464532 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 32464532 — Predictive Biomarker (PRD): CYP27A1 mRNA
Genes: CYP27A1; CYP27
Study 32464532 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 32464532 — Predictive Biomarker (PRD): NADSYN1 mRNA
Genes: NADSYN1
Study 32464532 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study 34767030 — Safety Biomarker (SAF): Hyaluronic acid
Study 32935997 — Predictive Biomarker (PRD): ESR1
Genes: NR3A1; Era; ER-alpha
Study 32907366 — Predictive Biomarker (PRD): F2RL3 mRNA
Genes: F2RL3; PAR4
Study 36183051 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 32381420 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32381420 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 32381420 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33752964 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 35038432 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32827269 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35679057 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 36263002 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 36263002 — Surrogate Endpoint (SUR): Blood pressure
Study 33229756 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 33964301 — Predictive Biomarker (PRD): SP2 mRNA
Genes: SP2; KIAA0048
Study 33964301 — Predictive Biomarker (PRD): SP3 mRNA
Genes: SP3
Study 33964301 — Predictive Biomarker (PRD): SP4 mRNA
Genes: SP4
Study 33964301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34786904 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33824113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36056369 — Surrogate Endpoint (SUR): Blood pressure
Study 32040591 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 32040591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34184544 — Surrogate Endpoint (SUR): Blood pressure
Study 34184544 — Safety Biomarker (SAF): Reactive oxygen species
Study 34184544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34231532 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32460790 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 32460790 — Surrogate Endpoint (SUR): Blood pressure
Study 35288066 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32576090 — Predictive Biomarker (PRD): KCNK3 mRNA
Genes: KCNK3; TASK; TASK1
Study 37910474 — Surrogate Endpoint (SUR): Blood pressure
Study 33021871 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36065653 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 34544599 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 35696185 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 32957364 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32957364 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32957364 — Surrogate Endpoint (SUR): Serum creatinine
Study 35583232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32538495 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 35419650 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 34152785 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 34152785 — Surrogate Endpoint (SUR): Blood pressure
Study 34229698 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 33115436 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35394159 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33608590 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33244575 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34209273 — Surrogate Endpoint (SUR): Blood pressure
Study 32717273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32717273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32717273 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32717273 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32717273 — Safety Biomarker (SAF): IL-6 and IL-10
Study 34214668 — Predictive Biomarker (PRD): VTN mRNA
Genes: VTN
Study 34214668 — Predictive Biomarker (PRD): SERPIND1 mRNA
Genes: SERPIND1; HCF2
Study 34214668 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 32967742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35292378 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 34412521 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 34412521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35040974 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35869554 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 34000661 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 34000661 — Predictive Biomarker (PRD): MASP2 mRNA
Genes: MASP2
Study 34000661 — Predictive Biomarker (PRD): NADK mRNA
Genes: NADK
Study 34000661 — Predictive Biomarker (PRD): RNF223 mRNA
Genes: RNF223
Study 32891418 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32891418 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32891418 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32891418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32723201 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 34585598 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32492293 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32681228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35014600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36125835 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36125835 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 36125835 — Safety Biomarker (SAF): BDNF
Study 35545412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35132952 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 32230954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34666412 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 32036372 — Surrogate Endpoint (SUR): Blood pressure
Study 32766331 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 32043288 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33464732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35001410 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35001410 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36399383 — Surrogate Endpoint (SUR): Blood pressure
Study 36399383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34359996 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 34359996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33297409 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 33790860 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 34672201 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 35653225 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 33141609 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32108382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32019854 — Predictive Biomarker (PRD): CXCR1 mRNA
Genes: CXCR1; CMKAR1; IL8RA
Study 33800577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33800577 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 33800577 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34890532 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 34821494 — Safety Biomarker (SAF): BDNF
Study 32138760 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 32138760 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 33802634 — Predictive Biomarker (PRD): RTEL1 mRNA
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 33802634 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 32036837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32036837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32036837 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 32036837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32036837 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 32036837 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32036837 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 34673844 — Predictive Biomarker (PRD): SHFL mRNA
Genes: SHFL; C19orf66; FLJ11286; IRAV; RYDEN; SFL
Study 32701116 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 32701116 — Surrogate Endpoint (SUR): Serum uric acid
Study 32701116 — Surrogate Endpoint (SUR): Serum creatinine
Study 32701116 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 35507447 — Safety Biomarker (SAF): BDNF
Study 32932330 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32481469 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 33801247 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34605192 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34659809 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35672572 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 35672572 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 32270959 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32133780 — Surrogate Endpoint (SUR): Blood pressure
Study 32994235 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 32150762 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 32088302 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 33291700 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 35387718 — Predictive Biomarker (PRD): NLRC4 mRNA
Genes: NLRC4; CARD12; CLAN; CLAN1; IPAF; UNQ6189/PRO20215
Study 35387718 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 32146123 — Surrogate Endpoint (SUR): Serum sodium
Study 32748028 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 35221683 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32330571 — Surrogate Endpoint (SUR): Blood pressure
Study 32019609 — Surrogate Endpoint (SUR): Blood pressure
Study 36684501 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 36684501 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 32934372 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34748059 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 34488392 — Predictive Biomarker (PRD): NPNT mRNA
Genes: NPNT; EGFL6L; POEM; UNQ295/PRO334
Study 32367880 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 33888426 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34273650 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33427961 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 33427961 — Surrogate Endpoint (SUR): Serum calcium
Study 32580838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32580838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34574492 — Surrogate Endpoint (SUR): Blood pressure
Study 32374371 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 34460933 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 34583841 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 32294346 — Predictive Biomarker (PRD): TAAR1 mRNA
Genes: TAAR1; TA1; TAR1; TRAR1
Study 35739147 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35381930 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 32266412 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 35255426 — Predictive Biomarker (PRD): NOX4 mRNA
Genes: NOX4; RENOX
Study 35255426 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 32416821 — Surrogate Endpoint (SUR): Bone mineral density
Study 33154056 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 33036471 — Surrogate Endpoint (SUR): Blood pressure
Study 33036471 — Surrogate Endpoint (SUR): Serum uric acid
Study 34467742 — Surrogate Endpoint (SUR): Bone mineral density
Study 35764016 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 32178705 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33791916 — Surrogate Endpoint (SUR): Blood pressure
Study 33791916 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34618716 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 33883174 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34116393 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study 32632246 — Predictive Biomarker (PRD): PTPRU mRNA
Genes: PTPRU; FMI; PCP2; PTPRO
Study 33592131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33592131 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 33592131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35042152 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 35042152 — Predictive Biomarker (PRD): EML4 mRNA
Genes: EML4; C2orf2; EMAPL4
Study 35042152 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 34233727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36868916 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36219237 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 37462593 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 32495860 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32495860 — Predictive Biomarker (PRD): MAPK1 mRNA
Genes: MAPK1; ERK2; PRKM1; PRKM2
Study 32495860 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 32495860 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32495860 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33396458 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 33396458 — Safety Biomarker (SAF): MTHFR
Study 32194219 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32932898 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32027542 — Surrogate Endpoint (SUR): Blood pressure
Study 35502234 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 34965954 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 34965954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34965954 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 34965954 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 34965954 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35557386 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32142961 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 32255580 — Safety Biomarker (SAF): Hyaluronic acid
Study 34218214 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34360293 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 34182611 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 34001174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34001174 — Surrogate Endpoint (SUR): Serum creatinine
Study 34001174 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34001174 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33734046 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 33887380 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33887380 — Safety Biomarker (SAF): BDNF
Study 32856608 — Surrogate Endpoint (SUR): Serum calcium
Study 32570252 — Predictive Biomarker (PRD): S1PR1 mRNA
Genes: S1PR1; CHEDG1; EDG1
Study 32570252 — Predictive Biomarker (PRD): S1PR5 mRNA
Genes: S1PR5; EDG8
Study 32570252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33876196 — Predictive Biomarker (PRD): SLC44A1 mRNA
Genes: SLC44A1; CD92; CDW92; CTL1
Study 33876196 — Predictive Biomarker (PRD): FMO3 mRNA
Genes: FMO3