TrialPanorama/TrialPanorama-database huggingface dataset:
Study 36055307 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35956400 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35956400 — Predictive Biomarker (PRD): BAAT mRNA
Genes: BAAT
Study 35956400 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 32684181 — Predictive Biomarker (PRD): MEST mRNA
Genes: MEST; PEG1
Study 34465809 — Predictive Biomarker (PRD): SERPINA4 mRNA
Genes: SERPINA4; KST; PI4
Study 34465809 — Safety Biomarker (SAF): Reactive oxygen species
Study 35866799 — Surrogate Endpoint (SUR): Blood pressure
Study 34975829 — Predictive Biomarker (PRD): TREM1 mRNA
Genes: TREM1
Study 34975829 — Safety Biomarker (SAF): IL-6 and IL-10
Study 36394874 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 35378821 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 35658479 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 35658479 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 35658479 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study 35020465 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33370173 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36193496 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36193496 — Monitoring Biomarker (MOI): Procalcitonin
Study 33478501 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 33478501 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33872045 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 35717008 — Surrogate Endpoint (SUR): Serum creatinine
Study 33433587 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33433587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33433587 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 35208580 — Predictive Biomarker (PRD): DDN mRNA
Genes: DDN; KIAA0749
Study 35915043 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35986234 — Predictive Biomarker (PRD): NUBP1 mRNA
Genes: NUBP1; NBP; NBP1
Study 35674827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32514678 — Surrogate Endpoint (SUR): Blood pressure
Study 33031287 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 35895514 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 33577946 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 32221587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32221587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32221587 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36301961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32623488 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 36328358 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32562153 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 32562153 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34536795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34536795 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 34536795 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 33017755 — Surrogate Endpoint (SUR): Blood pressure
Study 33444934 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 34715908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32150651 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32150651 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 32150651 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 32468187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33423318 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32539810 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32331029 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC18A2 mRNA
Genes: SLC18A2; SVMT; VMAT2
Study 34267242 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 34267242 — Predictive Biomarker (PRD): ACKR3 mRNA
Genes: ACKR3; CMKOR1; CXCR7; GPR159; RDC1
Study 34267242 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 34267242 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 32959582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32959582 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 36056913 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32652544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36123055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36123055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36123055 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34229607 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 34229607 — Surrogate Endpoint (SUR): Serum potassium
Study 34229607 — Surrogate Endpoint (SUR): Serum sodium
Study 34764182 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 32813829 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 35598891 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35598891 — Surrogate Endpoint (SUR): Blood pressure
Study 34291724 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 33523029 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33523029 — Surrogate Endpoint (SUR): Blood pressure
Study 33176725 — Predictive Biomarker (PRD): HRG mRNA
Genes: HRG
Study 33176725 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 33176725 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33176725 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33176725 — Predictive Biomarker (PRD): Hormone receptor
Study 33293818 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 33293818 — Surrogate Endpoint (SUR): Bone mineral density
Study 33293818 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35789389 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 35789389 — Surrogate Endpoint (SUR): Blood pressure
Study 35295605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35295605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36148493 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 34933984 — Surrogate Endpoint (SUR): Blood pressure
Study 32416645 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 32991337 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36067506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33684598 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 33684598 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 36067977 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 33067278 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 32442828 — Surrogate Endpoint (SUR): Blood pressure
Study 36399023 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 36399023 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33245002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32289619 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 32289619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32474920 — Surrogate Endpoint (SUR): Serum uric acid
Study 35366329 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35366329 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 35366329 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35366329 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 35366329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33895733 — Surrogate Endpoint (SUR): Blood pressure
Study 34252155 — Predictive Biomarker (PRD): ZDHHC6 mRNA
Genes: ZDHHC6; ZNF376
Study 32556204 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 32556204 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 33797501 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 36083488 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33839075 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32586399 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 33615388 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32467347 — Predictive Biomarker (PRD): IRF1 mRNA
Genes: IRF1
Study 32467347 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 32467347 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 32245308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32245308 — Safety Biomarker (SAF): Interleukin 1
Study 33134378 — Surrogate Endpoint (SUR): Blood pressure
Study 33021466 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 33021466 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36184068 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 36184068 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34775577 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33260063 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 33260063 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34739197 — Surrogate Endpoint (SUR): Blood pressure
Study 34739197 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34739197 — Surrogate Endpoint (SUR): Serum creatinine
Study 33734057 — Safety Biomarker (SAF): Interleukin 1
Study 36198291 — Surrogate Endpoint (SUR): Blood pressure
Study 33705623 — Surrogate Endpoint (SUR): Pathological complete response
Study 33183671 — Surrogate Endpoint (SUR): Blood pressure
Study 32825535 — Surrogate Endpoint (SUR): Blood pressure
Study 33838579 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 32079426 — Predictive Biomarker (PRD): STXBP5L mRNA
Genes: STXBP5L; KIAA1006; LLGL4
Study 36052694 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34797778 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 33744225 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33744225 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32825814 — Surrogate Endpoint (SUR): Blood pressure
Study 35720033 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 35720033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33300990 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 34189447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34189447 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 36329307 — Surrogate Endpoint (SUR): Blood pressure
Study 35055783 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35055783 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 34549819 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 33745292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33745292 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 33745292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33745292 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36267895 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34666379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 35429974 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 36129998 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35799272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 32725680 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34121413 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34121413 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32150484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32150484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32150484 — Surrogate Endpoint (SUR): Serum uric acid
Study 32304248 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35641124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35641124 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): miR-124
Study 35641124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33073523 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 34391006 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 34391006 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 35428258 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33547980 — Surrogate Endpoint (SUR): Sperm parameters
Study 34366282 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 36071409 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36071409 — Predictive Biomarker (PRD): Hormone receptor
Study 35126950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34750291 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35797219 — Surrogate Endpoint (SUR): Pathological complete response
Study 36435795 — Surrogate Endpoint (SUR): Blood pressure
Study 33087159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34492522 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 34492522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32857481 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 32857481 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 32857481 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 32857481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33213529 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 33025024 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 33025024 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 36414975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35913755 — Surrogate Endpoint (SUR): Bone mineral density
Study 33016374 — Surrogate Endpoint (SUR): Blood pressure
Study 35717820 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35717820 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33632904 — Surrogate Endpoint (SUR): Blood pressure
Study 32654156 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 35621054 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 34395624 — Surrogate Endpoint (SUR): Blood pressure
Study 33662334 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study 35238894 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35238894 — Surrogate Endpoint (SUR): Serum creatinine
Study 33336450 — Surrogate Endpoint (SUR): Blood pressure
Study 35315592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35308520 — Surrogate Endpoint (SUR): Blood pressure
Study 34139998 — Surrogate Endpoint (SUR): Blood pressure
Study 35697127 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 34836211 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34836211 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32017777 — Surrogate Endpoint (SUR): Blood pressure
Study 616389141 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32631422 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 32631422 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study 36062966 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35726291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35927745 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35927745 — Surrogate Endpoint (SUR): Blood pressure
Study 32589506 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study 35195075 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34157996 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34157996 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 34157996 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 32840297 — Surrogate Endpoint (SUR): Blood pressure
Study 34270810 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 33259976 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33171589 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33171589 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32890650 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 32519066 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35775451 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 36108767 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 36108767 — Predictive Biomarker (PRD): GCLC mRNA
Genes: GCLC; GLCL; GLCLC
Study 36108767 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 34972033 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 36029019 — Surrogate Endpoint (SUR): Blood pressure
Study 33974564 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33974564 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 33974564 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 35242500 — Surrogate Endpoint (SUR): Blood pressure
Study 35744008 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 34732660 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 34732660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35362766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 33604690 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 36329227 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 32933552 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35202848 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 33277607 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33026937 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33026937 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 33026937 — Predictive Biomarker (PRD): PLCG2 mRNA
Genes: PLCG2
Study 33026937 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33184024 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 33184024 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33184024 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 35500144 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 34018147 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34018147 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B