TrialPanorama/TrialPanorama-database huggingface dataset:
Study 36419389 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 36419389 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 34052121 — Surrogate Endpoint (SUR): Blood pressure
Study 34151818 — Surrogate Endpoint (SUR): Blood pressure
Study 32106141 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 34027030 — Surrogate Endpoint (SUR): Blood pressure
Study 32402681 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 34118609 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 35235659 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35835685 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 34693933 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33966435 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 33966435 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 32330183 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 32744441 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32744441 — Surrogate Endpoint (SUR): Blood pressure
Study 33280953 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35954922 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35954922 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 32145111 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 32145111 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32145111 — Predictive Biomarker (PRD): CD81 mRNA
Genes: CD81; TAPA1; TSPAN28
Study 33913511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33913217 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35596774 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32744373 — Surrogate Endpoint (SUR): Blood pressure
Study 32553151 — Predictive Biomarker (PRD): DGAT2 mRNA
Genes: DGAT2; HMFN1045; UNQ738/PRO1433
Study 33211592 — Surrogate Endpoint (SUR): Blood pressure
Study 34914868 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33295137 — Safety Biomarker (SAF): Hyaluronic acid
Study 33258566 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 33769666 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 33769666 — Predictive Biomarker (PRD): SCN8A mRNA
Genes: SCN8A; MED
Study 32975159 — Surrogate Endpoint (SUR): Blood pressure
Study 35405482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35405482 — Safety Biomarker (SAF): IL-6 and IL-10
Study 33278235 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 35691791 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 35691791 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 34003364 — Surrogate Endpoint (SUR): Blood pressure
Study 34003364 — Surrogate Endpoint (SUR): Bone mineral density
Study 35670063 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 35670063 — Safety Biomarker (SAF): DRD2
Study 36184545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36184545 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 32148083 — Predictive Biomarker (PRD): SH2B3 mRNA
Genes: SH2B3; LNK
Study 32148083 — Surrogate Endpoint (SUR): Blood pressure
Study 32148083 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34554643 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32286392 — Predictive Biomarker (PRD): ANGPTL5 mRNA
Genes: ANGPTL5; UNQ5795/PRO19600
Study 32286392 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32286392 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34601410 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 34601410 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 34966064 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study 34966064 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 33766805 — Surrogate Endpoint (SUR): Bone mineral density
Study 33179154 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32359741 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32359741 — Surrogate Endpoint (SUR): Blood pressure
Study 34871182 — Predictive Biomarker (PRD): TNFSF14 mRNA
Genes: TNFSF14; HVEML; LIGHT; UNQ391/PRO726
Study 32722015 — Surrogate Endpoint (SUR): Bone mineral density
Study 32722015 — Surrogate Endpoint (SUR): Blood pressure
Study 34514770 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 35644166 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 34733346 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33720873 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 35478978 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 35478978 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 35552172 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32558052 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 32003938 — Surrogate Endpoint (SUR): Blood pressure
Study 32003938 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33357247 — Surrogate Endpoint (SUR): Blood pressure
Study 35896083 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 33253354 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 35834528 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34608929 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 34004483 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 34004483 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 34004483 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34455435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34455435 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32931919 — Surrogate Endpoint (SUR): Blood pressure
Study 32147182 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36131603 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 36131603 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 35725494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34652968 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 32634774 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 34227954 — Surrogate Endpoint (SUR): Blood pressure
Study 34606387 — Predictive Biomarker (PRD): ADCY10 mRNA
Genes: ADCY10; SAC
Study 32747497 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32747497 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 33203707 — Predictive Biomarker (PRD): SLC23A1 mRNA
Genes: SLC23A1; SVCT1; YSPL3
Study 33203707 — Predictive Biomarker (PRD): SLC23A3 mRNA
Genes: SLC23A3; E2BP3; SVCT3
Study 33203707 — Predictive Biomarker (PRD): CHPT1 mRNA
Genes: CHPT1; CPT1; MSTP022
Study 33203707 — Predictive Biomarker (PRD): BCAS3 mRNA
Genes: BCAS3
Study 33203707 — Predictive Biomarker (PRD): SNRPF mRNA
Genes: SNRPF; PBSCF
Study 33203707 — Predictive Biomarker (PRD): RER1 mRNA
Genes: RER1
Study 33203707 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 33203707 — Predictive Biomarker (PRD): RGS14 mRNA
Genes: RGS14
Study 33203707 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 33203707 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 33992032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33992032 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 33992032 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 33992032 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33883079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33883079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35553356 — Surrogate Endpoint (SUR): Blood pressure
Study 33957242 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 33957242 — Surrogate Endpoint (SUR): Blood pressure
Study 32057567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32057567 — Surrogate Endpoint (SUR): Blood pressure
Study 33653757 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 32196623 — Surrogate Endpoint (SUR): Serum uric acid
Study 33756239 — Surrogate Endpoint (SUR): Blood pressure
Study 34275830 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34275830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34275830 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 33196606 — Surrogate Endpoint (SUR): Blood pressure
Study 33196606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32815921 — Surrogate Endpoint (SUR): Blood pressure
Study 35690783 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 616120383 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33092618 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 36028843 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 36028843 — Predictive Biomarker (PRD): ADH1B mRNA
Genes: ADH1B; ADH2
Study 33803814 — Safety Biomarker (SAF): Hyaluronic acid
Study 34559129 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35413644 — Surrogate Endpoint (SUR): Serum creatinine
Study 33155868 — Surrogate Endpoint (SUR): Blood pressure
Study 32467417 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 32467417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32467417 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 32740347 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 36442902 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33620419 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 33620419 — Pharmacodynamic Biomarker (PDY): Dermal blood flow
Study 32493523 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 32493523 — Surrogate Endpoint (SUR): Blood pressure
Study 35742280 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 35742280 — Safety Biomarker (SAF): BDNF
Study 32443695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32443695 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 32443695 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32443695 — Predictive Biomarker (PRD): RGS1 mRNA
Genes: RGS1; 1R20; BL34; IER1
Study 32443695 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 32443695 — Predictive Biomarker (PRD): DUSP2 mRNA
Genes: DUSP2; PAC1
Study 33375942 — Surrogate Endpoint (SUR): Blood pressure
Study 32033935 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32868680 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32868680 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32868680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34784577 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33625363 — Surrogate Endpoint (SUR): Blood pressure
Study 35488332 — Predictive Biomarker (PRD): DSPP mRNA
Genes: DSPP
Study 34370970 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32047578 — Surrogate Endpoint (SUR): Serum creatinine
Study 32047578 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 32047578 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 33122081 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 36027238 — Surrogate Endpoint (SUR): Blood pressure
Study 36418946 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33682262 — Predictive Biomarker (PRD): REG1A mRNA
Genes: REG1A; PSPS; PSPS1; REG
Study 35784723 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33820778 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 33820778 — Predictive Biomarker (PRD): IRF7 mRNA
Genes: IRF7
Study 33820778 — Predictive Biomarker (PRD): TCF7 mRNA
Genes: TCF7; TCF1
Study 34872117 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33586583 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33472757 — Surrogate Endpoint (SUR): Blood pressure
Study 34996820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33510184 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33510184 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36318322 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 32827410 — Surrogate Endpoint (SUR): Blood pressure
Study 34119566 — Surrogate Endpoint (SUR): Blood pressure
Study 33015926 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32641330 — Surrogate Endpoint (SUR): Blood pressure
Study 34708513 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34708513 — Surrogate Endpoint (SUR): Blood pressure
Study 32269052 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 32075010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32940893 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 32091032 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 35598154 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35807924 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 35807924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34237265 — Surrogate Endpoint (SUR): Blood pressure
Study 32493215 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 35780106 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 35780106 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35780106 — Surrogate Endpoint (SUR): Blood pressure
Study 35148020 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 35148020 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34322547 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32992570 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32798174 — Surrogate Endpoint (SUR): Blood pressure
Study 33591620 — Surrogate Endpoint (SUR): Blood pressure
Study 35982464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33430891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33430891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36428089 — Surrogate Endpoint (SUR): Blood pressure
Study 36654481 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 36654481 — Surrogate Endpoint (SUR): Serum testosterone
Study 33472675 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 33472675 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34808036 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34808036 — Predictive Biomarker (PRD): PCSK7 mRNA
Genes: PCSK7; LPC; PC7; PC8; SPC7
Study 34120223 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 34120223 — Predictive Biomarker (PRD): FUT1 mRNA
Genes: FUT1; H; HSC
Study 34120223 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32037380 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34750450 — Safety Biomarker (SAF): Reactive oxygen species
Study 32859329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34102020 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 34102020 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32428747 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 35200335 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 32898346 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 32898346 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 32898346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32521890 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32521890 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 32521890 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33207993 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33196153 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32883723 — Predictive Biomarker (PRD): PCBD1 mRNA
Genes: PCBD1; DCOH; PCBD
Study 35190972 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32659641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33073599 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 35426485 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study 32444540 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 36480811 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 34020388 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 34736768 — Safety Biomarker (SAF): Hyaluronic acid
Study 34275349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33583887 — Surrogate Endpoint (SUR): Blood pressure
Study 35078853 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33271428 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33271428 — Pharmacodynamic Biomarker (PDY): GATA-type zinc finger protein 1
Genes: ZGLP1; GLP1
Study 33810808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33810808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34850000 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 34850000 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33393402 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 35618939 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35618939 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 33106185 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 32448624 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 34233065 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 34233065 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32173916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35213415 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 35213415 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 35213415 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 35213415 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 34859852 — Monitoring Biomarker (MOI): Procalcitonin
Study 32200759 — Surrogate Endpoint (SUR): Blood pressure
Study 32485753 — Surrogate Endpoint (SUR): Blood pressure
Study 35587681 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36045520 — Surrogate Endpoint (SUR): Blood pressure
Study 32503620 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32503620 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32503620 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32503620 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32503620 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 32332634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2