TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT06039540 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05472506 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study NCT05850962 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05850962 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06578858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06336902 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06575257 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05528068 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06574113 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04851808 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05162417 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT05437679 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study NCT05437679 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05211024 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study NCT05091476 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05379452 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05368805 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT05272969 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05272969 — Predictive Biomarker (PRD): ACTN3 mRNA
Genes: ACTN3
Study NCT06160362 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04775485 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT06008223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06008223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06008223 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT06008223 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT06008223 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT06008223 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT06008223 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06484907 — Predictive Biomarker (PRD): ACTA1 mRNA
Genes: ACTA1; ACTA
Study NCT05309382 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study NCT05309382 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05036525 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05450133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06368375 — Predictive Biomarker (PRD): PRPF31 mRNA
Genes: PRPF31; PRP31
Study NCT05463380 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06068894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05838222 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04613128 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT05912946 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04276272 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04276272 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04276272 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06131918 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT05025293 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06418230 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study NCT06418230 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT05115045 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05684887 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00173667 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05669144 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05908162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05908162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05908162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05260593 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT05370014 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04457596 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06040632 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06023615 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05443711 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05325840 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04749407 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04670770 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT05176691 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04283227 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04283227 — Predictive Biomarker (PRD): ARSA mRNA
Genes: ARSA
Study NCT05026489 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT05904600 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT00006328 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05507606 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06283004 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04942080 — Predictive Biomarker (PRD): CALR mRNA
Genes: CALR; CRTC
Study NCT06279507 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06546150 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06486142 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06351462 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05458674 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05275140 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05835544 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05439629 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06600815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06097962 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06097962 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT06097962 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05684861 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study NCT06435455 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03533153 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT06573957 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05670028 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04960813 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study NCT06351735 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT05101278 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study NCT05101278 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT05699564 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04734379 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04772287 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04772287 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06368128 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05417347 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04812457 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05356585 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06043973 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06043973 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT06487143 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05471440 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06096077 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT06189209 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT05140083 — Predictive Biomarker (PRD): NEB mRNA
Genes: NEB
Study NCT05795153 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05984394 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05984394 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT05984394 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT04992195 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06560541 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06560541 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT05360238 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT05360238 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT06216210 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT06216210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05252559 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT05654727 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05817149 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT06536075 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study NCT04982042 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05428111 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06602921 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05780762 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study NCT05993455 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05993455 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05165264 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05322538 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06197139 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT04421339 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT05513183 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06127069 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT04796675 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05753020 — Predictive Biomarker (PRD): CKM mRNA
Genes: CKM; CKMM
Study NCT05519839 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06242938 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03825536 — Predictive Biomarker (PRD): TAAR1 mRNA
Genes: TAAR1; TA1; TAR1; TRAR1
Study NCT05775731 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT05775731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05775731 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT05751915 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study NCT05278611 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT06205511 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05908240 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05515783 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05434585 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06078553 — Predictive Biomarker (PRD): DOK7 mRNA
Genes: DOK7; C4orf25
Study NCT06033989 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05052671 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05768399 — Predictive Biomarker (PRD): TNFSF18 mRNA
Genes: TNFSF18; AITRL; GITRL; TL6; UNQ149/PRO175
Study NCT00006493 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT00006493 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT05015725 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT06136065 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT06042764 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04955236 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04928807 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05401318 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study NCT06035458 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05567679 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study NCT05178563 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06017869 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT06017869 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT06535152 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05175469 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study NCT05189977 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05369065 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05468905 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06545695 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06545695 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04775966 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04751877 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT04652830 — Predictive Biomarker (PRD): DRAM1 mRNA
Genes: DRAM1; DRAM
Study NCT05864118 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04903795 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05117606 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05192252 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT04676113 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT04676113 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06401278 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05689294 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01540604 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01540604 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study NCT06105775 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05835726 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT05803083 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05640895 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05640895 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04369157 — Predictive Biomarker (PRD): AZGP1 mRNA
Genes: AZGP1; ZAG; ZNGP1
Study NCT06159049 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT06435611 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05363332 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05574777 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT04394884 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT06351722 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT06351722 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06351722 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT06351722 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT05077267 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05188131 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT05188131 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT05188131 — Surrogate Endpoint (SUR): Serum sodium
Study NCT05178511 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06259175 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05132855 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06572319 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04547985 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT05777109 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT05777109 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05248776 — Predictive Biomarker (PRD): FFAR1 mRNA
Genes: FFAR1; GPR40
Study NCT06210035 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04959305 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01298882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01298882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05103761 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05995236 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05784610 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT05230693 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study NCT06368271 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study NCT06173076 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study NCT05829629 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT06298006 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study NCT06187077 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05535829 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT05535829 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT05535829 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05752669 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study NCT05752669 — Predictive Biomarker (PRD): NOX4 mRNA
Genes: NOX4; RENOX
Study NCT06260553 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06260553 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05562661 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05511337 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT05106296 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT05106296 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00002435 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05869981 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT05185024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06532006 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05963997 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05963997 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05963997 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05963997 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05029791 — Predictive Biomarker (PRD): ZEB1 mRNA
Genes: ZEB1; AREB6; TCF8
Study NCT06514313 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study NCT05604742 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT06584149 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT05939960 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT05235802 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05933668 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05933668 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT06205082 — Predictive Biomarker (PRD): TNFRSF10C mRNA
Genes: TNFRSF10C; DCR1; LIT; TRAILR3; TRID; UNQ321/PRO366
Study NCT04091243 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00959777 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05061628 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study NCT06141200 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04940884 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study NCT04940884 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study NCT06336070 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06389812 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06389812 — Safety Biomarker (SAF): BDNF
Study NCT04411186 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT00000802 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05616377 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06171152 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06171152 — Safety Biomarker (SAF): BDNF
Study NCT06172829 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05852275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05395364 — Surrogate Endpoint (SUR): Blood pressure