TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT06107842 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04222335 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04222335 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04231266 — Predictive Biomarker (PRD): GNE mRNA
Genes: GNE; GLCNE
Study NCT04231266 — Safety Biomarker (SAF): N-acetylneuraminic acid
Study NCT05479097 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05737797 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT05420311 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06662084 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT06661148 — Monitoring Biomarker (MOI): HBV DNA
Study NCT06659458 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06661564 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06657859 — Predictive Biomarker (PRD): PMM2 mRNA
Genes: PMM2
Study NCT06607666 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT06607666 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT05858853 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT05538312 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT06440967 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05787587 — Predictive Biomarker (PRD): PARG mRNA
Genes: PARG
Study NCT05247957 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study NCT05315674 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT05979220 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05979220 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05655559 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04727632 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT04972682 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT05570110 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06329063 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT05349409 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06279364 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05605275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05605275 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT04635384 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT04635384 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05851079 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT05806515 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT05806515 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT05578287 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06481878 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04566393 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04566393 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT04566393 — Predictive Biomarker (PRD): HRAS mRNA
Genes: HRAS; HRAS1
Study NCT06497062 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study NCT06661239 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06611345 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study NCT05097677 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06094842 — Predictive Biomarker (PRD): L1CAM mRNA
Genes: L1CAM; CAML1; MIC5
Study NCT06094842 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05593913 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04659499 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06162663 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04628169 — Predictive Biomarker (PRD): ZEB1 mRNA
Genes: ZEB1; AREB6; TCF8
Study NCT04628169 — Safety Biomarker (SAF): Netrin-1
Genes: NTN1; NTN1L
Study NCT05609994 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT05609994 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT06447623 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06447623 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05867433 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04731480 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05658159 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05725005 — Safety Biomarker (SAF): Beta-N-acetylhexosaminidase
Genes: OGA; HEXC; KIAA0679; MEA5; MGEA5
Study NCT05004974 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT05004974 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT05004974 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT06162559 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05030519 — Surrogate Endpoint (SUR): Bacterial count
Study NCT05723562 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT05088746 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT04728477 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06090864 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT06090864 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study NCT05901480 — Predictive Biomarker (PRD): OTOF mRNA
Genes: OTOF; FER1L2
Study NCT06561880 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT03686306 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05475665 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00013663 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT06661161 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06607380 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04577300 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study NCT04851119 — Predictive Biomarker (PRD): TBL1X mRNA
Genes: TBL1X; TBL1
Study NCT06104488 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT05058612 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04915170 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT05305118 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05289817 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05141708 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05141708 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06013358 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05749510 — Predictive Biomarker (PRD): MRNIP mRNA
Genes: MRNIP; C5orf45
Study NCT05749510 — Predictive Biomarker (PRD): NONO mRNA
Genes: NONO; NRB54
Study NCT05749510 — Predictive Biomarker (PRD): NOP53 mRNA
Genes: NOP53; GLT; GLTSCR2; PICT1
Study NCT05099354 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04587843 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05870150 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study NCT03184935 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05427448 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06365216 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT05263986 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05873153 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06215703 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study NCT05486572 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT05468190 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT06659016 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04601428 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT05179668 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05149586 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study NCT06138015 — Safety Biomarker (SAF): BDNF
Study NCT06377943 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study NCT06397937 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05058196 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05058196 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04348747 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05065892 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04717336 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04852705 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04852705 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04133701 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05935891 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05935891 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05259137 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05540561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT05340621 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT05340621 — Safety Biomarker (SAF): RAS pathway
Study NCT04644237 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04909008 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT06659068 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06659068 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT04703608 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05048836 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05683678 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT06145633 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04786704 — Predictive Biomarker (PRD): SDC2 mRNA
Genes: SDC2; HSPG1
Study NCT04303078 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT05164263 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05885074 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05049707 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04802135 — Predictive Biomarker (PRD): KCNQ2 mRNA
Genes: KCNQ2
Study NCT06436573 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study NCT04775862 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04775862 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04775862 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT06188650 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study NCT05487651 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00190021 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT06584331 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00162500 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT05577312 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04812119 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CTNNB1 mRNA
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study NCT04640493 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06112951 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study NCT04173260 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT05014464 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06605586 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT06606561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06606561 — Predictive Biomarker (PRD): ADAMTS4 mRNA
Genes: ADAMTS4; KIAA0688; UNQ769/PRO1563
Study NCT06606561 — Predictive Biomarker (PRD): ADAMTS5 mRNA
Genes: ADAMTS5; ADAMTS11; ADMP2
Study NCT06606561 — Predictive Biomarker (PRD): ADAMTS7 mRNA
Genes: ADAMTS7
Study NCT06606561 — Predictive Biomarker (PRD): ADAMTS12 mRNA
Genes: ADAMTS12; UNQ1918/PRO4389
Study NCT06606561 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06606561 — Safety Biomarker (SAF): miR-320
Study NCT06606561 — Predictive Biomarker (PRD): miR-320c
Study NCT06606678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06379958 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05804513 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05211804 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05211804 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05815212 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05639153 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT05226780 — Predictive Biomarker (PRD): SCN8A mRNA
Genes: SCN8A; MED
Study NCT05430191 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT04867226 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT05964530 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05964530 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05978492 — Predictive Biomarker (PRD): ENPP1 mRNA
Genes: ENPP1; M6S1; NPPS; PC1; PDNP1
Study NCT04271748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04817137 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04783714 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04783714 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT06355609 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06018493 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06386796 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05991193 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05849714 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT04903873 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT04580368 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT06605547 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT06658951 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06607510 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT06607328 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06239441 — Predictive Biomarker (PRD): IL5RA mRNA
Genes: IL5RA; IL5R
Study NCT06239441 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT06195969 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04895293 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05008575 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT04709328 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05988294 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05467839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04936763 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05825937 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00002161 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06007755 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05044754 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT05044754 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05473273 — Predictive Biomarker (PRD): PIBF1 mRNA
Genes: PIBF1; C13orf24; PIBF
Study NCT05473273 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT05473273 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT05473273 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT05473273 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT05275647 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT05275647 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study NCT03209063 — Safety Biomarker (SAF): MTHFR
Study NCT06431568 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05798390 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05834647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05408130 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04720729 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04720729 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04720729 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05071183 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04881357 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT05616156 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04915755 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04915755 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05567055 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04776707 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT06098378 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT06244069 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study NCT06244069 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study NCT06244069 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study NCT05889598 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06435533 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05965024 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05045144 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05125328 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05621343 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT05174039 — Predictive Biomarker (PRD): CLN3 mRNA
Genes: CLN3; BTS
Study NCT05188209 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05188209 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04928677 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT06316531 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05133687 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05576727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04611763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04611763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05862532 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05862532 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05293756 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05102110 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04886986 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05993611 — Predictive Biomarker (PRD): CD6 mRNA
Genes: CD6
Study NCT05096845 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05141721 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05603559 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05815316 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05295927 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT06443762 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT06443762 — Predictive Biomarker (PRD): MDM4 mRNA
Genes: MDM4; MDMX
Study NCT04853342 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04853342 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01037387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05848167 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06310330 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT04819555 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04819555 — Pharmacodynamic Biomarker (PDY): Guanine nucleotide exchange factor C9orf72
Genes: C9orf72; DENND9; DENNL72
Study NCT05828199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06036576 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT06145360 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06145360 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT05930730 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06211725 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study NCT06370156 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study NCT06300164 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT06323460 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05589740 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06092086 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05944029 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05428540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2