TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05435430 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05002465 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05481450 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT06246396 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05031377 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05546866 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05946252 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06133842 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05784441 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT05954078 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05745194 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05745194 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05704530 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03909321 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04607642 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04733989 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06171360 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06171360 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06171360 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05716191 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT04776343 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01220778 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT05936736 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01196208 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT04846036 — Predictive Biomarker (PRD): ZFYVE9 mRNA
Genes: ZFYVE9; MADHIP; SARA; SMADIP
Study NCT04876092 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study NCT06229509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04669899 — Predictive Biomarker (PRD): LILRB2 mRNA
Genes: LILRB2; ILT4; LIR2; MIR10
Study NCT06331260 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT06129786 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06129786 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05778149 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05778149 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT06322576 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04485637 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05159193 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT05237739 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT06245616 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT00002185 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05332561 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05888116 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05000801 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT05454423 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT05454423 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05162755 — Predictive Biomarker (PRD): KLRC1 mRNA
Genes: KLRC1; NKG2A
Study NCT05162755 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05162755 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06255600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT06730659 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT04842513 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT04649385 — Predictive Biomarker (PRD): MAP4K1 mRNA
Genes: MAP4K1; HPK1
Study NCT06422884 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05777564 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06590792 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT05529771 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06600412 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study NCT06600412 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03861676 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06680830 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT00002267 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06683950 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06683950 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study NCT04909021 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05468320 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT06765681 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06766591 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06767020 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT04934514 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04902443 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06769295 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05513976 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT05480618 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06108479 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT06769555 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06769555 — Surrogate Endpoint (SUR): Hematologic response
Study NCT05578976 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06130254 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05446090 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT06769893 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT06657534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04927299 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05178901 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06769022 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06768255 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT04681131 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04681131 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04681131 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT06380140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06380140 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06380140 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT05080829 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04754711 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06344442 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT05326724 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study NCT05814354 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06765031 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study NCT05077813 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT05077813 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT05077813 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT00001128 — Safety Biomarker (SAF): Interleukin 12
Study NCT05030857 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04715217 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04715217 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT04460963 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study NCT04460963 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study NCT04460963 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT04460963 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study NCT04460963 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT05898802 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06085066 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT06769425 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study NCT06763783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06763783 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06763783 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05165251 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05165251 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05735405 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05977543 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05977543 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05737706 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04373122 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06062238 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT05765383 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT05765383 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study NCT06333782 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05085002 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05085002 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05732129 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT05335941 — Predictive Biomarker (PRD): MTAP mRNA
Genes: MTAP; MSAP
Study NCT04893668 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04893668 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study NCT04893668 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05806671 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05806671 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05806671 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05770531 — Predictive Biomarker (PRD): TACSTD2 mRNA
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study NCT05770531 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05857228 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04854005 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04854005 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05949281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05949281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06445582 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study NCT05751031 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT06023108 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study NCT05741203 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05741203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06365307 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05512325 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05357183 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04624659 — Surrogate Endpoint (SUR): Hemoglobin response rate
Study NCT04632199 — Predictive Biomarker (PRD); Safety Biomarker (SAF): NTSR1 mRNA
Genes: NTSR1; NTRR
Study NCT02723435 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05184257 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05175885 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study NCT06653777 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT06420466 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05121337 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06593522 — Predictive Biomarker (PRD): MTAP mRNA
Genes: MTAP; MSAP
Study NCT06447454 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT06656312 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT04902872 — Predictive Biomarker (PRD): CBX1 mRNA
Genes: CBX1; CBX
Study NCT06585982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05786040 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06654193 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04595084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05660135 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05660135 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04972760 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT04972760 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT04972760 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study NCT05237388 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study NCT06071013 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05574036 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT05290220 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06495541 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06030622 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT05522075 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06051396 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT06051396 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04619420 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05548933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05548933 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05548933 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT05548933 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05548933 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT05548933 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05528133 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05528133 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05279378 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT05279378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05426343 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05426343 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05524987 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05094336 — Predictive Biomarker (PRD): MTAP mRNA
Genes: MTAP; MSAP
Study NCT05374785 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT05374785 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study NCT05374785 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT04903223 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study NCT05498272 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT04884971 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04974307 — Predictive Biomarker (PRD): CLN3 mRNA
Genes: CLN3; BTS
Study NCT05562141 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06004661 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05339516 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT06488105 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06488105 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00002379 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04372498 — Predictive Biomarker (PRD): KCNN4 mRNA
Genes: KCNN4; IK1; IKCA1; KCA4; SK4
Study NCT05811910 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study NCT05811910 — Predictive Biomarker (PRD): CEP72 mRNA
Genes: CEP72; KIAA1519
Study NCT04676243 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05290467 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06394622 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT04837677 — Predictive Biomarker (PRD): Induced myeloid leukemia cell differentiation protein Mcl-1
Genes: MCL1; BCL2L3
Study NCT05782387 — Predictive Biomarker (PRD): MCOLN1 mRNA
Genes: MCOLN1; ML4; TRPML1; MSTP080
Study NCT06477328 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT06335147 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04304261 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06041776 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05476796 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05771571 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05771571 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06010875 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT04723407 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05738980 — Predictive Biomarker (PRD): FRK mRNA
Genes: FRK; PTK5; RAK
Study NCT04015557 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study NCT04015557 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04850950 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04412993 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT05080231 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05954104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04757337 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT05651087 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05450406 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05450406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06730932 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study NCT05233579 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study NCT05764070 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04853329 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04973657 — Predictive Biomarker (PRD): AMN mRNA
Genes: AMN; UNQ513/PRO1028
Study NCT04973657 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study NCT06491667 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06491667 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT06491667 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT06229678 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05752318 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study NCT06637540 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05522933 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06206395 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06206395 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06398392 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT05956197 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT05420493 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05661201 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05661201 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study NCT05543434 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05646550 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06356324 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04124367 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04124367 — Safety Biomarker (SAF): BDNF
Study NCT05702944 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05171829 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04782115 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF