TrialPanorama/TrialPanorama-database huggingface dataset:
Study 37721703 — Predictive Biomarker (PRD): HHEX mRNA
Genes: HHEX; HEX; PRH; PRHX
Study 37721754 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 37721786 — Surrogate Endpoint (SUR): Forced vital capacity
Study 37722087 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37722354 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 37722482 — Surrogate Endpoint (SUR): Blood pressure
Study 37722559 — Surrogate Endpoint (SUR): Blood pressure
Study 37722831 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 37723113 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 37723113 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 37723115 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 37723356 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 37723439 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 37723577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37723577 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 37723590 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 37723590 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 37723590 — Predictive Biomarker (PRD): PAX5 mRNA
Genes: PAX5
Study 37723590 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 37723590 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 37723590 — Predictive Biomarker (PRD): JUN mRNA
Genes: JUN
Study 37723837 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37725576 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 37725576 — Predictive Biomarker (PRD): FIP1L1 mRNA
Genes: FIP1L1; FIP1; RHE
Study 37725919 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 37725919 — Surrogate Endpoint (SUR): Serum potassium
Study 37725919 — Surrogate Endpoint (SUR): Blood pressure
Study 37726656 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 37726656 — Surrogate Endpoint (SUR): Blood pressure
Study 37726889 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 37727636 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37728045 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37728115 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 37728142 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 37728406 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 37728803 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 37728803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37728917 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 37728978 — Predictive Biomarker (PRD): THEMIS mRNA
Genes: THEMIS; C6orf190; C6orf207
Study 37728978 — Monitoring Biomarker (MOI): Cell-free DNA
Study 37729024 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 37729076 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 37729076 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 37729184 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 37729613 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 37730501 — Predictive Biomarker (PRD): OSMR mRNA
Genes: OSMR; OSMRB
Study 37730501 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 37730501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37730530 — Surrogate Endpoint (SUR): Serum calcium
Study 37730530 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 37730613 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 37730614 — Safety Biomarker (SAF): Nicotinamide phosphoribosyltransferase
Genes: NAMPT; PBEF; PBEF1
Study 37730614 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 37730614 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study 37730674 — Predictive Biomarker (PRD): BCL11A mRNA
Genes: BCL11A; CTIP1; EVI9; KIAA1809; ZNF856
Study 37730689 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 37730689 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 37731394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37731394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37731394 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37731491 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 37731938 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 37732489 — Surrogate Endpoint (SUR): Blood pressure
Study 37732619 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 37732619 — Safety Biomarker (SAF): BDNF
Study 37732961 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 37732990 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 37733159 — Surrogate Endpoint (SUR): Blood pressure
Study 37733364 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37733364 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 37733479 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 37733977 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 37733980 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 37734091 — Surrogate Endpoint (SUR): Blood pressure
Study 37734399 — Surrogate Endpoint (SUR): Pathological complete response
Study 37734899 — Surrogate Endpoint (SUR): Serum potassium
Study 37735443 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 37735543 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 37735543 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 37735543 — Surrogate Endpoint (SUR): Platelet count response
Study 37735756 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37737132 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 37737952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37738088 — Predictive Biomarker (PRD): NRM mRNA
Genes: NRM; NRM29; UNQ555/PRO1112
Study 37738125 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 37738125 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 37738329 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 37738626 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 37738655 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 37739167 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 37739684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37739719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37740107 — Safety Biomarker (SAF): Hyaluronic acid
Study 37740179 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study 37740179 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 37740179 — Safety Biomarker (SAF): IL-6 and IL-10
Study 37740588 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 37740923 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 37740926 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 37741273 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37741832 — Predictive Biomarker (PRD): ATG16L1 mRNA
Genes: ATG16L1; APG16L; UNQ9393/PRO34307
Study 37741832 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 37741832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37741921 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 37742328 — Surrogate Endpoint (SUR): Serum creatinine
Study 37742745 — Monitoring Biomarker (MOI): HBV DNA
Study 37742911 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 37742911 — Surrogate Endpoint (SUR): Blood pressure
Study 37742911 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 37743665 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 37744345 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 37744351 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 37744732 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 37745109 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 37745159 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 37745159 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 37745288 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 37745371 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37745604 — Surrogate Endpoint (SUR): Blood pressure
Study 37746068 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37747626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37747734 — Surrogate Endpoint (SUR): Blood pressure
Study 37748109 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 37748493 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37748493 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 37748693 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37748693 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 37748693 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37749601 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 37751015 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37751019 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37751022 — Surrogate Endpoint (SUR): Forced vital capacity
Study 37751113 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37751207 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 37751286 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 37751301 — Predictive Biomarker (PRD): GLP1R mRNA
Genes: GLP1R
Study 37751455 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37751561 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37751948 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37751961 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 37752337 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37752344 — Predictive Biomarker (PRD): TYMS
Genes: Tsase; TMS; HsT422
Study 37752423 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 37752423 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 37752423 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 37752426 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study 37752426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37752426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37752621 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 37753336 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37753640 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 37753808 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 37753808 — Safety Biomarker (SAF): Nucleotide triphosphate diphosphatase NUDT15
Genes: NUDT15; MTH2
Study 37753954 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 37755958 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 37756299 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37757966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37758711 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37758711 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 37759324 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37759330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37765154 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 37766505 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37766505 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 37766731 — Surrogate Endpoint (SUR): Serum triglycerides
Study 37766884 — Surrogate Endpoint (SUR): Blood pressure
Study 37767823 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 37768273 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 37768273 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 37768317 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 37768317 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 37768317 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 37768317 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 37768344 — Surrogate Endpoint (SUR): Blood pressure
Study 37768658 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study 37768658 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37768670 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37768670 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37768671 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 37768719 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 37768980 — Surrogate Endpoint (SUR): Blood pressure
Study 37769113 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 37769182 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 37769181 — Surrogate Endpoint (SUR): Blood pressure
Study 37769187 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 37769314 — Surrogate Endpoint (SUR): Blood pressure
Study 37769319 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 37769428 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 37769429 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 37770277 — Surrogate Endpoint (SUR): Blood pressure
Study 37770704 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 37770770 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37770889 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 37772721 — Surrogate Endpoint (SUR): Serum creatinine
Study 37773418 — Surrogate Endpoint (SUR): Probing pocket depth
Study 37773498 — Surrogate Endpoint (SUR): Blood pressure
Study 37774014 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 37774014 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37774188 — Surrogate Endpoint (SUR): Blood pressure
Study 37774646 — Surrogate Endpoint (SUR): Blood pressure
Study 37774697 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 37774841 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37775290 — Surrogate Endpoint (SUR): Blood pressure
Study 37775584 — Safety Biomarker (SAF): Hyaluronic acid
Study 37775612 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 37775744 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 37776214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37776235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37776326 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 37776510 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 37776510 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 37776953 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37777018 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study 37777018 — Predictive Biomarker (PRD): NR4A3 mRNA
Genes: NR4A3; CHN; CSMF; MINOR; NOR1; TEC
Study 37777600 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 37777743 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 37777806 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37778358 — Surrogate Endpoint (SUR): Platelet count response
Study 37778526 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 37778613 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 37779919 — Predictive Biomarker (PRD): STING1 mRNA
Genes: STING1; ERIS; MITA; STING; TMEM173
Study 37780770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37781158 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 37781158 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 37781161 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 37781916 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 37781916 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 37782150 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 37782356 — Surrogate Endpoint (SUR): Serum uric acid
Study 37782421 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 37782758 — Predictive Biomarker (PRD): Liver iron
Study 37783456 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 37783459 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 37783459 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 37783459 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37783805 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study 37783947 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 37783966 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 37783966 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 37783966 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 37783970 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 37784053 — Safety Biomarker (SAF): Hyaluronic acid
Study 37784110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37784200 — Predictive Biomarker (PRD): PELI1 mRNA
Genes: PELI1; PRISM
Study 37786277 — Predictive Biomarker (PRD): Hormone receptor
Study 37786451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37787643 — Predictive Biomarker (PRD): EIF2AK1 mRNA
Genes: EIF2AK1; HRI; KIAA1369; PRO1362
Study 37787790 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 37787790 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 37787906 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 37788414 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 37789228 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 37789266 — Surrogate Endpoint (SUR): Forced vital capacity
Study 37790218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37790298 — Safety Biomarker (SAF): Reactive oxygen species
Study 37790298 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37790298 — Surrogate Endpoint (SUR): Blood pressure
Study 37790374 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37790490 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37790490 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 37790490 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study 37790490 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 37790695 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 37791480 — Surrogate Endpoint (SUR): Blood pressure
Study 37792065 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 37792260 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 37792612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37792612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37793085 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 37793771 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38