TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35461831 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33764198 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 34412699 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 36316084 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 32344842 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32344842 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study 32344842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32344842 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 35674370 — Surrogate Endpoint (SUR): Blood pressure
Study 35674370 — Surrogate Endpoint (SUR): Serum triglycerides
Study 35674370 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32029306 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 34329567 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 34329567 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 34329567 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 34329567 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 34329567 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 34329567 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 34329567 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34878629 — Predictive Biomarker (PRD): AGBL2 mRNA
Genes: AGBL2; CCP2
Study 33419635 — Predictive Biomarker (PRD): SLC25A20 mRNA
Genes: SLC25A20; CAC; CACT
Study 33230010 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 35157994 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35157994 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35157994 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35850159 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 33559704 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34957660 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33496831 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 33496831 — Surrogate Endpoint (SUR): Bone mineral density
Study 32842270 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 32842270 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32842270 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32842270 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32761731 — Surrogate Endpoint (SUR): Blood pressure
Study 32350297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33382529 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32588042 — Predictive Biomarker (PRD): TCP1 mRNA
Genes: TCP1; CCT1; CCTA
Study 32301122 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 36111243 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 34617375 — Surrogate Endpoint (SUR): Bone mineral density
Study 34214937 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33495205 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 32356926 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 35151026 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35151026 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33145864 — Surrogate Endpoint (SUR): Blood pressure
Study 32107532 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32107532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36479595 — Predictive Biomarker (PRD): SELENOP mRNA
Genes: SELENOP; SELP; SEPP1
Study 35287231 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 32438479 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 35915040 — Surrogate Endpoint (SUR): Blood pressure
Study 34333922 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 35500594 — Surrogate Endpoint (SUR): Blood pressure
Study 35643855 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 32659365 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 35027012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35536828 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 32692113 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33471681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33471681 — Surrogate Endpoint (SUR): Blood pressure
Study 33471681 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 32627803 — Surrogate Endpoint (SUR): Blood pressure
Study 34197676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34197676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34417205 — Surrogate Endpoint (SUR): Blood pressure
Study 36306706 — Predictive Biomarker (PRD): MXD1 mRNA
Genes: MXD1; MAD
Study 33185990 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33185990 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 33581692 — Surrogate Endpoint (SUR): Bone mineral density
Study 33581692 — Surrogate Endpoint (SUR): Serum calcium
Study 34093551 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 616191017 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 36093918 — Predictive Biomarker (PRD): GRIN2B mRNA
Genes: GRIN2B; NMDAR2B
Study 36093918 — Predictive Biomarker (PRD): GRIA1 mRNA
Genes: GRIA1; GLUH1; GLUR1
Study 36093918 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36093918 — Safety Biomarker (SAF): BDNF
Study 32369295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34392667 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 32275363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32275363 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33233946 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32561903 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 35458222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33208019 — Surrogate Endpoint (SUR): Blood pressure
Study 33208019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33208019 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 34973513 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33788463 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 36101809 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36101809 — Surrogate Endpoint (SUR): Blood pressure
Study 32188310 — Surrogate Endpoint (SUR): Blood pressure
Study 32375572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32375572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32375572 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36219978 — Predictive Biomarker (PRD): PIM3 mRNA
Genes: PIM3
Study 35872874 — Surrogate Endpoint (SUR): Blood pressure
Study 32979512 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 32979512 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 34560112 — Surrogate Endpoint (SUR): Blood pressure
Study 32203751 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 34162631 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33479442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33058957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 34939776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35445358 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 35445358 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 35445358 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 35685555 — Surrogate Endpoint (SUR): Blood pressure
Study 35457686 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 34536915 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 33036254 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 33036254 — Predictive Biomarker (PRD): KLF4 mRNA
Genes: KLF4; EZF; GKLF
Study 33036254 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 34339623 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36267853 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35745249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33630712 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32781263 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32781263 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 33797479 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32569130 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 34323055 — Predictive Biomarker (PRD): ROPN1L mRNA
Genes: ROPN1L; ASP; RSPH11
Study 35786344 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 32371165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33606045 — Surrogate Endpoint (SUR): Bone mineral density
Study 35835925 — Safety Biomarker (SAF): Hyaluronic acid
Study 35403841 — Surrogate Endpoint (SUR): Pathological complete response
Study 33337592 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33337592 — Surrogate Endpoint (SUR): Blood pressure
Study 32007324 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33904329 — Predictive Biomarker (PRD): TUB mRNA
Genes: TUB
Study 33904329 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 32823839 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 33200892 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 36098051 — Surrogate Endpoint (SUR): Blood pressure
Study 34743149 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34743149 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32517663 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 34988724 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 35473729 — Surrogate Endpoint (SUR): Blood pressure
Study 34351401 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 34351401 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 33518062 — Safety Biomarker (SAF): Bacteroidetes phylum
Study 33858976 — Surrogate Endpoint (SUR): Bone mineral density
Study 32589648 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 34984822 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34984822 — Pharmacodynamic Biomarker (PDY): RAS peptides
Study 33492703 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33492703 — Safety Biomarker (SAF): BDNF
Study 35101346 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 35101346 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 35658800 — Surrogate Endpoint (SUR): Blood pressure
Study 36040917 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33631112 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 33631112 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33631112 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 36162037 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34283906 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34283906 — Surrogate Endpoint (SUR): Blood pressure
Study 35809280 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 35809280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32957318 — Surrogate Endpoint (SUR): Serum sodium
Study 33191835 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 33965603 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 35162372 — Surrogate Endpoint (SUR): Blood pressure
Study 36163944 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 36163944 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32898010 — Predictive Biomarker (PRD): LY86 mRNA
Genes: LY86; MD1
Study 32898010 — Predictive Biomarker (PRD): SH2D1A mRNA
Genes: SH2D1A; DSHP; SAP
Study 32898010 — Predictive Biomarker (PRD): CD247 mRNA
Genes: CD247; CD3Z; T3Z; TCRZ
Study 32898010 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study 32898010 — Predictive Biomarker (PRD): CR2 mRNA
Genes: CR2; C3DR
Study 32898010 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 32898010 — Predictive Biomarker (PRD): LAMP3 mRNA
Genes: LAMP3; DCLAMP; TSC403
Study 32898010 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 32898010 — Predictive Biomarker (PRD): DUSP4 mRNA
Genes: DUSP4; MKP2; VH2
Study 32898010 — Predictive Biomarker (PRD): SELL mRNA
Genes: SELL; LNHR; LYAM1
Study 33743490 — Surrogate Endpoint (SUR): Blood pressure
Study 33341915 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 33891379 — Predictive Biomarker (PRD): IL17F
Genes: IL-17F; ML-1; ML1
Study 33891379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33872652 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 35363301 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 35363301 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 35363301 — Predictive Biomarker (PRD): MTOR
Genes: RAFT1; RAPT1; FLJ44809
Study 34847073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34847073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33495601 — Surrogate Endpoint (SUR): Bone mineral density
Study 33047257 — Surrogate Endpoint (SUR): Blood pressure
Study 32277824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35236646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35665782 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35665782 — Predictive Biomarker (PRD): Hormone receptor
Study 32616329 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32616329 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 35571447 — Predictive Biomarker (PRD): TBCB mRNA
Genes: TBCB; CG22; CKAP1
Study 32959223 — Surrogate Endpoint (SUR): Sperm parameters
Study 32270483 — Surrogate Endpoint (SUR): Blood pressure
Study 36311634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32829410 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 33510284 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35598084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33120078 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study 33120078 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35136981 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 35987694 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32651141 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32651141 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32651141 — Surrogate Endpoint (SUR): Serum creatinine
Study 35365594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35365594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35365594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32066284 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 32066284 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32066284 — Predictive Biomarker (PRD): SFRP1 mRNA
Genes: SFRP1; FRP; FRP1; SARP2
Study 32066284 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32066284 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 32066284 — Safety Biomarker (SAF): Reactive oxygen species
Study 35876511 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 32474744 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32474744 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 32474744 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 34868479 — Predictive Biomarker (PRD): PCBD1 mRNA
Genes: PCBD1; DCOH; PCBD
Study 33528893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32320566 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 32320566 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 36167537 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34365883 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34256795 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 33492083 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 33156760 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34997360 — Safety Biomarker (SAF): Hyaluronic acid
Study 33367229 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 32407608 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 33827851 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32567233 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32567233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32954768 — Surrogate Endpoint (SUR): Blood pressure
Study 36450449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32934343 — Predictive Biomarker (PRD): TFF1 mRNA
Genes: TFF1; BCEI; PS2
Study 32934343 — Predictive Biomarker (PRD): ADAM12 mRNA
Genes: ADAM12; MLTN; UNQ346/PRO545
Study 35489749 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 32731981 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33139537 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 33139537 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 33139537 — Predictive Biomarker (PRD): KLB mRNA
Genes: KLB
Study 33196487 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34041968 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34041968 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32023184 — Surrogate Endpoint (SUR): Blood pressure
Study 35623879 — Surrogate Endpoint (SUR): Blood pressure
Study 35623879 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33070235 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 35720032 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 35720032 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study 35299115 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32320078 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32320078 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 34853625 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 33030703 — Surrogate Endpoint (SUR): Blood pressure
Study 34973039 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 32537238 — Surrogate Endpoint (SUR): Blood pressure
Study 33441772 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22