TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33821793 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 34413443 — Predictive Biomarker (PRD): CLYBL mRNA
Genes: CLYBL; CLB
Study 34019540 — Surrogate Endpoint (SUR): Blood pressure
Study 34019540 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34234262 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34234262 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36440217 — Surrogate Endpoint (SUR): Bone mineral density
Study 36440217 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 33988659 — Safety Biomarker (SAF): Reactive oxygen species
Study 33988659 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 34582373 — Surrogate Endpoint (SUR): Serum creatinine
Study 616037435 — Surrogate Endpoint (SUR): Blood pressure
Study 33963742 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 33544819 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 34772901 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34772901 — Predictive Biomarker (PRD): SOD3 mRNA
Genes: SOD3
Study 34772901 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 34772901 — Predictive Biomarker (PRD): GPX3 mRNA
Genes: GPX3; GPXP
Study 34772901 — Predictive Biomarker (PRD): GPX4 mRNA
Genes: GPX4
Study 34772901 — Predictive Biomarker (PRD): GPX7 mRNA
Genes: GPX7; GPX6; UNQ469/PRO828
Study 34772901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34772901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34772901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32368027 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36056874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33272965 — Predictive Biomarker (PRD): TMPRSS6 mRNA
Genes: TMPRSS6; UNQ354/PRO618
Study 33272965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33272965 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33272965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33942396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32367400 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32367400 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 34041633 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34729060 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34729060 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33963688 — Predictive Biomarker (PRD): Microsatellite instability
Study 36372869 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33568662 — Predictive Biomarker (PRD): TRPC6 mRNA
Genes: TRPC6; TRP6
Study 33568662 — Predictive Biomarker (PRD): PNOC mRNA
Genes: PNOC; OFQ
Study 33568662 — Predictive Biomarker (PRD): PATJ mRNA
Genes: PATJ; CIPP; INADL
Study 33568662 — Surrogate Endpoint (SUR): Blood pressure
Study 36047035 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36047035 — Safety Biomarker (SAF): BDNF
Study 33908691 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33908691 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 33908691 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33975465 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33975465 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33003575 — Surrogate Endpoint (SUR): Blood pressure
Study 36163755 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 36163755 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34336162 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34336162 — Predictive Biomarker (PRD): FSCN1 mRNA
Genes: FSCN1; FAN1; HSN; SNL
Study 34336162 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 35818232 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35818232 — Predictive Biomarker (PRD): Microsatellite instability
Study 35276977 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 32687174 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 32914890 — Predictive Biomarker (PRD): KCNAB1 mRNA
Genes: KCNAB1; KCNA1B
Study 32914890 — Predictive Biomarker (PRD): PLCH1 mRNA
Genes: PLCH1; KIAA1069; PLCL3
Study 34791836 — Predictive Biomarker (PRD): FANCA mRNA
Genes: FANCA; FAA; FACA; FANCH
Study 34791836 — Predictive Biomarker (PRD): ANXA6 mRNA
Genes: ANXA6; ANX6
Study 34791836 — Predictive Biomarker (PRD): BTG1 mRNA
Genes: BTG1
Study 34791836 — Predictive Biomarker (PRD): PARP10 mRNA
Genes: PARP10
Study 34791836 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 34791836 — Predictive Biomarker (PRD): CARD11 mRNA
Genes: CARD11; CARMA1
Study 34791836 — Predictive Biomarker (PRD): ATP6AP1 mRNA
Genes: ATP6AP1; ATP6IP1; ATP6S1; VATPS1; XAP3
Study 34791836 — Predictive Biomarker (PRD): SOCS1 mRNA
Genes: SOCS1; SSI1; TIP3
Study 34791836 — Predictive Biomarker (PRD): TBL1XR1 mRNA
Genes: TBL1XR1; IRA1; TBLR1
Study 32921364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32921364 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32921364 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 33568796 — Predictive Biomarker (PRD): GRIK1 mRNA
Genes: GRIK1; GLUR5
Study 36039531 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34035112 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 34035112 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34035112 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33743112 — Predictive Biomarker (PRD): TBP mRNA
Genes: TBP; GTF2D1; TF2D; TFIID
Study 33306991 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34347216 — Predictive Biomarker (PRD): PIR mRNA
Genes: PIR
Study 32270926 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 32270926 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 32270926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32143570 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 36228640 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33030089 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 34858915 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34351728 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 35718794 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 34107141 — Surrogate Endpoint (SUR): Blood pressure
Study 32579807 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 35210467 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 32437937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32203968 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 32203968 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34481803 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34481803 — Surrogate Endpoint (SUR): Urinary oxalate
Study 33191341 — Predictive Biomarker (PRD): DKK3 mRNA
Genes: DKK3; REIC; UNQ258/PRO295
Study 34362453 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 34362453 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 34362453 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 34362453 — Predictive Biomarker (PRD): PTCHD3 mRNA
Genes: PTCHD3; PTR
Study 34481524 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 34481517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32531968 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 33847862 — Surrogate Endpoint (SUR): Blood pressure
Study 35924333 — Surrogate Endpoint (SUR): Blood pressure
Study 32855972 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 33837098 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 33837098 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34106300 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35533724 — Surrogate Endpoint (SUR): Blood pressure
Study 34320508 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32102617 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32276630 — Predictive Biomarker (PRD): NKD1 mRNA
Genes: NKD1; NKD; PP7246
Study 35466438 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 32813290 — Predictive Biomarker (PRD): SIGLEC1 mRNA
Genes: SIGLEC1; SN
Study 32813290 — Predictive Biomarker (PRD): SLC40A1 mRNA
Genes: SLC40A1; FPN; FPN1; IREG1; SLC11A3; MSTP079
Study 35101276 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 34323542 — Predictive Biomarker (PRD): Hormone receptor
Study 32701720 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 34051886 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33309354 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 35288148 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 32382172 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 35144649 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33564126 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 33564126 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 34089431 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 34587217 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32238091 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33497537 — Surrogate Endpoint (SUR): Blood pressure
Study 35104665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34802257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34802257 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34802257 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 34289056 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 33651182 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 35983677 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 34209131 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 34209131 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 34209131 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 34209131 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 34774639 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34774639 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33183576 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 32106792 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32106792 — Surrogate Endpoint (SUR): Bone mineral density
Study 35201671 — Surrogate Endpoint (SUR): Blood pressure
Study 33677781 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 33677781 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36018510 — Surrogate Endpoint (SUR): Blood pressure
Study 35120306 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 35120306 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35732620 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 35732620 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34925341 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 34925341 — Safety Biomarker (SAF): C-X-C motif chemokine 5
Genes: CXCL5; ENA78; SCYB5
Study 34925341 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 32467034 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 36364858 — Surrogate Endpoint (SUR): Blood pressure
Study 36364858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 32827752 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32827752 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32827752 — Surrogate Endpoint (SUR): Blood pressure
Study 35675051 — Predictive Biomarker (PRD): CRABP2 mRNA
Genes: CRABP2
Study 35675051 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 35380268 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 33663549 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32673517 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32673517 — Surrogate Endpoint (SUR): Blood pressure
Study 32727729 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32462607 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 34821431 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 35134093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35041780 — Surrogate Endpoint (SUR): Serum creatinine
Study 35460295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35460295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34499218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32869587 — Predictive Biomarker (PRD): ANO1 mRNA
Genes: ANO1; DOG1; ORAOV2; TAOS2; TMEM16A
Study 33268345 — Safety Biomarker (SAF): Human leucocyte antigen
Study 34449939 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 36414206 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33618146 — Surrogate Endpoint (SUR): Blood pressure
Study 32202265 — Predictive Biomarker (PRD): SLC6A20 mRNA
Genes: SLC6A20; SIT1; XT3; XTRP3
Study 32202265 — Predictive Biomarker (PRD): SLC38A2 mRNA
Genes: SLC38A2; ATA2; KIAA1382; SAT2; SNAT2
Study 32578332 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 35183773 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 35183773 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 33404156 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35297493 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33587120 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 33587120 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33587120 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35365179 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 36172943 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 33132076 — Surrogate Endpoint (SUR): Blood pressure
Study 34689841 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 32598950 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 33630641 — Surrogate Endpoint (SUR): Blood pressure
Study 32342266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36357602 — Predictive Biomarker (PRD): ZC3H12D mRNA
Genes: ZC3H12D; C6orf95; MCPIP4; TFL
Study 33685834 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33685834 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 33685834 — Predictive Biomarker (PRD): GGH mRNA
Genes: GGH
Study 33685834 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35229407 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 33852887 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33852887 — Surrogate Endpoint (SUR): Blood pressure
Study 35266409 — Surrogate Endpoint (SUR): Blood pressure
Study 33256659 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 35468601 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35468601 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33374033 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 33374033 — Safety Biomarker (SAF): Arginase-1
Genes: ARG1
Study 33421333 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 32663820 — Surrogate Endpoint (SUR): Blood pressure
Study 35773718 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33921952 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 33342328 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34166299 — Safety Biomarker (SAF): BDNF
Study 33675794 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 35855954 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 33929807 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 32851809 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study 36271942 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34226217 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 34226217 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 34226217 — Surrogate Endpoint (SUR): Blood pressure
Study 32393252 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 33938832 — Surrogate Endpoint (SUR): Blood pressure
Study 35905657 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36114460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34260829 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34260829 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34260829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 35488182 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 35792831 — Safety Biomarker (SAF): Hyaluronic acid
Study 35063028 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 32852619 — Safety Biomarker (SAF): Hyaluronic acid
Study 32169297 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33323545 — Surrogate Endpoint (SUR): Bone mineral density
Study 32384175 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 33620545 — Surrogate Endpoint (SUR): Blood pressure
Study 35665223 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35665223 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 36463547 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36463547 — Predictive Biomarker (PRD): Hormone receptor
Study 33103938 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33061328 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32559257 — Surrogate Endpoint (SUR): Blood pressure
Study 33377972 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 33377972 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33377972 — Predictive Biomarker (PRD): Hormone receptor
Study 32065880 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32065880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32065880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32065880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32707226 — Surrogate Endpoint (SUR): Blood pressure
Study 35986418 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 32687091 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 34957008 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 33958436 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 34452927 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34452927 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 34452927 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 35439033 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 34358701 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 33206670 — Surrogate Endpoint (SUR): Bone mineral density
Study 36163874 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 32800913 — Surrogate Endpoint (SUR): Serum potassium
Study 32800913 — Surrogate Endpoint (SUR): Serum creatinine
Study 34931749 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33290538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33270989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32575387 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 36177001 — Predictive Biomarker (PRD): C4BPA mRNA
Genes: C4BPA; C4BP