TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32941962 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33257487 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 34101691 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 32009778 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 35658048 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 33498049 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 33498049 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32498098 — Predictive Biomarker (PRD): FNTA mRNA
Genes: FNTA
Study 32800386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 35159318 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 35081595 — Surrogate Endpoint (SUR): Blood pressure
Study 33657114 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33657114 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33200221 — Predictive Biomarker (PRD): CBX4 mRNA
Genes: CBX4
Study 32552387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35813442 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34597297 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34597297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34597297 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 33796993 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 33765513 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33765513 — Predictive Biomarker (PRD): Hormone receptor
Study 33154022 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33154022 — Predictive Biomarker (PRD): Hormone receptor
Study 33895428 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 33165570 — Surrogate Endpoint (SUR): Blood pressure
Study 32740676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34918967 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 33530919 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33530919 — Surrogate Endpoint (SUR): Blood pressure
Study 35681510 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 34460181 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 34460181 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 36383487 — Surrogate Endpoint (SUR): Blood pressure
Study 35368946 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35368946 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study 35368946 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 34791970 — Surrogate Endpoint (SUR): Blood pressure
Study 32598752 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32598752 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 34963300 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33491287 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 33491287 — Surrogate Endpoint (SUR): Blood pressure
Study 32195897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32195897 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 32195897 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32195897 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32195897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32740291 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 35748295 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33141785 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study 34724345 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 33428870 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 34817733 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 32977992 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 34942176 — Surrogate Endpoint (SUR): Blood pressure
Study 35091076 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 33677046 — Predictive Biomarker (PRD): TPH2 mRNA
Genes: TPH2; NTPH
Study 34298555 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 35869719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35869719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35869719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33910562 — Predictive Biomarker (PRD): RHOF mRNA
Genes: RHOF; ARHF; RIF
Study 33910562 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 33910562 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 32499757 — Surrogate Endpoint (SUR): Bone mineral density
Study 35680254 — Predictive Biomarker (PRD): YES1 mRNA
Genes: YES1; YES
Study 32083979 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32083979 — Surrogate Endpoint (SUR): Blood pressure
Study 36496126 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 32510754 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32510754 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32510754 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32197931 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36065795 — Surrogate Endpoint (SUR): Blood pressure
Study 36065795 — Surrogate Endpoint (SUR): Serum potassium
Study 36209245 — Surrogate Endpoint (SUR): Bone mineral density
Study 33422517 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 32321483 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 33357531 — Surrogate Endpoint (SUR): Blood pressure
Study 33556109 — Predictive Biomarker (PRD): DGUOK mRNA
Genes: DGUOK; DGK
Study 33556109 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 33556109 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 33556109 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 33556109 — Predictive Biomarker (PRD): AGXT mRNA
Genes: AGXT; AGT1; SPAT
Study 33556109 — Predictive Biomarker (PRD): AASS mRNA
Genes: AASS
Study 33556109 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 35153168 — Surrogate Endpoint (SUR): Blood pressure
Study 35193666 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 33866313 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 35146694 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35146694 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 33040561 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33040561 — Surrogate Endpoint (SUR): Blood pressure
Study 32736596 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 32736596 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 33620716 — Predictive Biomarker (PRD): NOX5 mRNA
Genes: NOX5
Study 33620716 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33620716 — Predictive Biomarker (PRD): HSPA1A mRNA
Genes: HSPA1A; HSP72; HSPA1; HSX70
Study 34395475 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 33652233 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 32809271 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 33838113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32385506 — Surrogate Endpoint (SUR): Blood pressure
Study 33831896 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 35775313 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35253265 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 36045426 — Predictive Biomarker (PRD): MEFV mRNA
Genes: MEFV; MEF; TRIM20
Study 35291694 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 35291694 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32075834 — Surrogate Endpoint (SUR): Blood pressure
Study 35673524 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34260595 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34260595 — Surrogate Endpoint (SUR): Blood pressure
Study 32827399 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33130235 — Surrogate Endpoint (SUR): Serum creatinine
Study 33130235 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 36476543 — Surrogate Endpoint (SUR): Blood pressure
Study 34292203 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34292203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33950735 — Surrogate Endpoint (SUR): Blood pressure
Study 36394849 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36394849 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 36394849 — Predictive Biomarker (PRD): Hormone receptor
Study 33371454 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 33782413 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 33782413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36261447 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 34237976 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35147195 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35945818 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 36437523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36437523 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36437523 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36437523 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 34294550 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 36196478 — Surrogate Endpoint (SUR): Blood pressure
Study 32832550 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 32962980 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32962980 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32962980 — Predictive Biomarker (PRD): Hormone receptor
Study 34336000 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 34336000 — Predictive Biomarker (PRD): NAV2 mRNA
Genes: NAV2; HELAD1; KIAA1419; POMFIL2; RAINB1; STEERIN2
Study 34336000 — Predictive Biomarker (PRD): RFC3 mRNA
Genes: RFC3
Study 32746835 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 32134128 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 35237342 — Surrogate Endpoint (SUR): Blood pressure
Study 34678887 — Surrogate Endpoint (SUR): Blood pressure
Study 34768161 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 36054319 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 32363613 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 33636344 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 33892287 — Predictive Biomarker (PRD): KCNQ2 mRNA
Genes: KCNQ2
Study 33892287 — Predictive Biomarker (PRD): SCN2A mRNA
Genes: SCN2A; NAC2; SCN2A1; SCN2A2
Study 33892287 — Predictive Biomarker (PRD): KCNB1 mRNA
Genes: KCNB1
Study 32495862 — Predictive Biomarker (PRD): CBX7 mRNA
Genes: CBX7
Study 32495862 — Safety Biomarker (SAF): miR-18a
Genes: MIR18A
Study 34527078 — Surrogate Endpoint (SUR): Serum uric acid
Study 34527078 — Surrogate Endpoint (SUR): Blood pressure
Study 32513507 — Surrogate Endpoint (SUR): Blood pressure
Study 36257695 — Surrogate Endpoint (SUR): Blood pressure
Study 33263418 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36355805 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 34918971 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34918971 — Surrogate Endpoint (SUR): Blood pressure
Study 34918971 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35599912 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35901983 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 35901983 — Surrogate Endpoint (SUR): Blood pressure
Study 33919513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 32238507 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 35551291 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32074953 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32074953 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33814451 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 35576638 — Safety Biomarker (SAF): Interleukin 1
Study 32712801 — Surrogate Endpoint (SUR): Blood pressure
Study 33620008 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 33620008 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 33710166 — Surrogate Endpoint (SUR): Blood pressure
Study 34648192 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 34648192 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 34648192 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 35851187 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34565001 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34911731 — Predictive Biomarker (PRD): SCAMP1 mRNA
Genes: SCAMP1; SCAMP
Study 35965421 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35906663 — Predictive Biomarker (PRD): DCLRE1C mRNA
Genes: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C
Study 33811685 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 33811685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34537448 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35066509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36178909 — Surrogate Endpoint (SUR): Blood pressure
Study 32366554 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 36163806 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 34628889 — Surrogate Endpoint (SUR): Serum calcium
Study 34628889 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 35861850 — Surrogate Endpoint (SUR): Blood pressure
Study 35164488 — Surrogate Endpoint (SUR): Blood pressure
Study 35237338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35237338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35237338 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 34687398 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34238445 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35576957 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study 33083852 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 33514427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33514427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33514427 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 34196886 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34196886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35054083 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 35054083 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 33914140 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 32544350 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 32544350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35766355 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 33899971 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 35508923 — Surrogate Endpoint (SUR): Blood pressure
Study 33100327 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 35103059 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study 35554758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35554758 — Surrogate Endpoint (SUR): Blood pressure
Study 34518109 — Surrogate Endpoint (SUR): Blood pressure
Study 34967126 — Surrogate Endpoint (SUR): Blood pressure
Study 33181169 — Surrogate Endpoint (SUR): Blood pressure
Study 35057599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35057599 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32703511 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 34160113 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35150818 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35150818 — Surrogate Endpoint (SUR): Blood pressure
Study 32969197 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 615918992 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 615918992 — Predictive Biomarker (PRD): DTL mRNA
Genes: DTL; CDT2; CDW1; DCAF2; L2DTL; RAMP
Study 615918992 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study 33972404 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 33972404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32044319 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 32044319 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32044319 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32960514 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 35710576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32677772 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 35239136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35322373 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 32623928 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 36306029 — Predictive Biomarker (PRD): MC1R mRNA
Genes: MC1R; MSHR
Study 33188552 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33580248 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 34518072 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32341121 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 32681717 — Surrogate Endpoint (SUR): Serum creatinine
Study 35413921 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32638445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32979516 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study 34333502 — Surrogate Endpoint (SUR): Bacterial count
Study 33894153 — Surrogate Endpoint (SUR): Serum calcium
Study 34197339 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36279373 — Predictive Biomarker (PRD): BLOC1S2 mRNA
Genes: BLOC1S2; BLOS2; CEAP
Study 36062743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34738962 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study 36229048 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 36229048 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34022750 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 34022750 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 32771596 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35725017 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 34975007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34975007 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33176232 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL