TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05940857 — Predictive Biomarker (PRD): OPTN mRNA
Genes: OPTN; FIP2; GLC1E; HIP7; HYPL; NRP
Study NCT06096090 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04832724 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05567770 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00001106 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06166095 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06166095 — Safety Biomarker (SAF): BDNF
Study NCT05745272 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01970137 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05092152 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05435846 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05297773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05297773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05297773 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05297773 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT05297773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05273047 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05884502 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00000907 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05549206 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04919031 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04919031 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06103578 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Sclerostin
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study NCT06103578 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study NCT06103578 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT06103578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06301906 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05740709 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06113432 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04965259 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT04907539 — Predictive Biomarker (PRD): RNF43 mRNA
Genes: RNF43
Study NCT06094673 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT06094673 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05647473 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05428488 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05428488 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05306301 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT05306301 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04962633 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06014489 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT06242314 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study NCT05573984 — Predictive Biomarker (PRD): PRPF31 mRNA
Genes: PRPF31; PRP31
Study NCT04812054 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT04812054 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT05569187 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05569187 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06226766 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06443970 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05164042 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05366244 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05087095 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study NCT05163028 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05163028 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04718467 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05321433 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05769790 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05543525 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT06287528 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06287528 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT00002433 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT06151795 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04843644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04843644 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT06398054 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study NCT04608786 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05601986 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04896320 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06510946 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05414279 — Surrogate Endpoint (SUR): Serum sodium
Study NCT05568147 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT05787197 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06187155 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study NCT06136156 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05807555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05417568 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT03435939 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03435939 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT05147545 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06285058 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05749575 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05749575 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05749575 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05232240 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05783362 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study NCT06155942 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT06362187 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT06201533 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06210490 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05847075 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study NCT06229496 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT01730755 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT01730755 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT01730755 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study NCT06371404 — Predictive Biomarker (PRD): HDAC6 mRNA
Genes: HDAC6; KIAA0901; JM21
Study NCT06450626 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06539559 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06539559 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT06539559 — Predictive Biomarker (PRD): CBR1 mRNA
Genes: CBR1; CBR; CRN; SDR21C1
Study NCT05214482 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05214482 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study NCT05569850 — Surrogate Endpoint (SUR): Bacterial count
Study NCT05187793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04666233 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05584644 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05584644 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05584644 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05019365 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05019365 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05040854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05040854 — Safety Biomarker (SAF): Interleukin 12
Study NCT05550506 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05376644 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05793970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05423028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02808260 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study NCT06403735 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05162547 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06390969 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT05990309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05990309 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study NCT05440578 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06057870 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04958629 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT05433129 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06393712 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study NCT06646107 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06585553 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT05757622 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05972369 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT06269185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05958524 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06095492 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06095492 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT06632418 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study NCT04320602 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT06720987 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06721611 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05831995 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT05499507 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05379400 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05379400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05135845 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05135845 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05497076 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06425263 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05462405 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05636904 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT05316480 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05903950 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04741789 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05255991 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06450964 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT04784052 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05460533 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05772455 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT06661018 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT05051293 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT06554288 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT06554288 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT05899673 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT06141772 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04881045 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study NCT04193397 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05356195 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05302271 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study 34188144 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 34188144 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33646060 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32876328 — Surrogate Endpoint (SUR): Bone mineral density
Study 32213642 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 34477316 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32471387 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 36070046 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 35565689 — Surrogate Endpoint (SUR): Serum triglycerides
Study 35565689 — Safety Biomarker (SAF): Reactive oxygen species
Study 33036537 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 36274534 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32631080 — Surrogate Endpoint (SUR): Blood pressure
Study 33751917 — Safety Biomarker (SAF): Hyaluronic acid
Study 34984626 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 34033222 — Predictive Biomarker (PRD): CXCR1 mRNA
Genes: CXCR1; CMKAR1; IL8RA
Study 34033222 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32063251 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 36279931 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34424991 — Predictive Biomarker (PRD): SUCO mRNA
Genes: SUCO; C1orf9; CH1; OPT; SLP1
Study 36315949 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32475444 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 35775872 — Safety Biomarker (SAF): Hyaluronic acid
Study 35442180 — Surrogate Endpoint (SUR): Blood pressure
Study 34270830 — Surrogate Endpoint (SUR): Blood pressure
Study 33446053 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 36202740 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32423584 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32608001 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 36060658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32342848 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33518452 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 33518452 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33518452 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 33518452 — Monitoring Biomarker (MOI): Angiopoietin 1 receptor
Genes: TEK; TIE2; VMCM; VMCM1
Study 33518452 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 35106809 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34514739 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33998004 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 34579009 — Safety Biomarker (SAF): Reactive oxygen species
Study 34535143 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33858011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34241691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33956387 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 35201518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35201518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35201518 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 33164319 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 36033577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36033577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34366152 — Surrogate Endpoint (SUR): Blood pressure
Study 32291607 — Predictive Biomarker (PRD): TNNT1 mRNA
Genes: TNNT1; TNT
Study 33228794 — Surrogate Endpoint (SUR): Blood pressure
Study 33611615 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 33031748 — Safety Biomarker (SAF): SLC51A mRNA
Genes: SLC51A; OSTA
Study 33031748 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 36227931 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36227931 — Surrogate Endpoint (SUR): Pathological complete response
Study 34795208 — Predictive Biomarker (PRD): MYB mRNA
Genes: MYB
Study 35658650 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 33058735 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 32358661 — Safety Biomarker (SAF): Hyaluronic acid
Study 34535524 — Surrogate Endpoint (SUR): Blood pressure
Study 32506481 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study 32771068 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34320937 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 35093596 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 35842566 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 34111810 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 36001055 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33376301 — Safety Biomarker (SAF): DRD2
Study 36084228 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 35763229 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35763229 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35763229 — Predictive Biomarker (PRD): Hormone receptor
Study 33524981 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 33524981 — Surrogate Endpoint (SUR): Serum sodium
Study 33313759 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 33313759 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 34172825 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34172825 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34172825 — Surrogate Endpoint (SUR): Blood pressure
Study 32681134 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 37142054 — Predictive Biomarker (PRD): HSD11B2 mRNA
Genes: HSD11B2; HSD11K; SDR9C3
Study 37142054 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33704352 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33704352 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33713718 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33713718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33046070 — Surrogate Endpoint (SUR): Blood pressure
Study 35934778 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 32147484 — Monitoring Biomarker (MOI): HBV DNA
Study 35213721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35213721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35447934 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32615659 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 32615659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35477483 — Surrogate Endpoint (SUR): Blood pressure
Study 32234756 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32234756 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 32234756 — Predictive Biomarker (PRD): SMAD4 mRNA
Genes: SMAD4; DPC4; MADH4