TrialPanorama/TrialPanorama-database huggingface dataset:
Study 37793792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37793853 — Predictive Biomarker (PRD): FGFR1
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 37793853 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 37794050 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37794185 — Predictive Biomarker (PRD): PTPN2 mRNA
Genes: PTPN2; PTPT
Study 37794185 — Predictive Biomarker (PRD): PTPN1 mRNA
Genes: PTPN1; PTP1B
Study 37794220 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 37794395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37794395 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 37794395 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 37794472 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 37794472 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 37794590 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 37794802 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 37795976 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37796114 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 37797293 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37797387 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37797387 — Predictive Biomarker (PRD): Hormone receptor
Study 37797965 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 37798422 — Predictive Biomarker (PRD): HNF1A mRNA
Genes: HNF1A; TCF1
Study 37798468 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 37798658 — Surrogate Endpoint (SUR): Blood pressure
Study 37798671 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37798801 — Surrogate Endpoint (SUR): Blood pressure
Study 37798863 — Predictive Biomarker (PRD): PHLDA2 mRNA
Genes: PHLDA2; BWR1C; HLDA2; IPL; TSSC3
Study 37800112 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37800597 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 37800597 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 37800597 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 37800633 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 37801454 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 37801622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37801622 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 37801622 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 37801628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37801674 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 37801674 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37802088 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 37802088 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 37802567 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37802608 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 37802608 — Surrogate Endpoint (SUR): Pathological complete response
Study 37803017 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 37803017 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 37803017 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 37803017 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 37803017 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 37803037 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 37803037 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 37803037 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 37803098 — Surrogate Endpoint (SUR): Blood pressure
Study 37803759 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 37804189 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 37804202 — Surrogate Endpoint (SUR): Blood pressure
Study 37804307 — Surrogate Endpoint (SUR): Serum creatinine
Study 37804344 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 37804344 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 37804430 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 37804569 — Predictive Biomarker (PRD): ARSI mRNA
Genes: ARSI
Study 37804765 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 37804765 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 37805024 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 37805216 — Monitoring Biomarker (MOI): Cell-free DNA
Study 37805481 — Surrogate Endpoint (SUR): Blood pressure
Study 37805496 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37805496 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 37805496 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37805496 — Predictive Biomarker (PRD): Hormone receptor
Study 37805496 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 37806074 — Predictive Biomarker (PRD): DIABLO mRNA
Genes: DIABLO; SMAC
Study 37806333 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 37806372 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 37806651 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 37807179 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 37807937 — Predictive Biomarker (PRD): Liver iron
Study 37810589 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 37810589 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 37810917 — Predictive Biomarker (PRD): PTER mRNA
Genes: PTER
Study 37811343 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37811343 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37811343 — Predictive Biomarker (PRD): Hormone receptor
Study 37811523 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 37811634 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 37811634 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 37812242 — Monitoring Biomarker (MOI): Procalcitonin
Study 37812381 — Surrogate Endpoint (SUR): Blood pressure
Study 37812476 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 37812476 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37812518 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 37812518 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 37813418 — Surrogate Endpoint (SUR): Blood pressure
Study 37813479 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 37813841 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 37814061 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 37814121 — Predictive Biomarker (PRD): RBM39 mRNA
Genes: RBM39; HCC1; RNPC2
Study 37814224 — Surrogate Endpoint (SUR): Serum creatinine
Study 37814224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37814266 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 37814306 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 37814541 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37814892 — Surrogate Endpoint (SUR): Blood pressure
Study 37815489 — Monitoring Biomarker (MOI): Cell-free DNA
Study 37815684 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37815684 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37815684 — Predictive Biomarker (PRD): Hormone receptor
Study 37815865 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 37815865 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37816010 — Surrogate Endpoint (SUR): Blood pressure
Study 37816208 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 37816552 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 37816552 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 37817147 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 37817263 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37817267 — Surrogate Endpoint (SUR): Blood pressure
Study 37817285 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 37817285 — Surrogate Endpoint (SUR): Blood pressure
Study 37817565 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 37817565 — Surrogate Endpoint (SUR): Pathological complete response
Study 37818166 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 37818166 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 37818403 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 37819505 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37819505 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 37819544 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 37819656 — Surrogate Endpoint (SUR): Blood pressure
Study 37819872 — Surrogate Endpoint (SUR): Blood pressure
Study 37819936 — Predictive Biomarker (PRD): CHEK1 mRNA
Genes: CHEK1; CHK1
Study 37819954 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37820539 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 37821131 — Surrogate Endpoint (SUR): Serum creatinine
Study 37821461 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 37821472 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37822710 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 37822710 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37822710 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 37822710 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 37822710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37822710 — Safety Biomarker (SAF): BDNF
Study 37822710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37822872 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37822872 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37823031 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 37823469 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 37823729 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 37824131 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 37824155 — Surrogate Endpoint (SUR): Blood pressure
Study 37824197 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 37824197 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 37824197 — Safety Biomarker (SAF): BDNF
Study 37826992 — Predictive Biomarker (PRD): GATM mRNA
Genes: GATM; AGAT
Study 37828493 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 37828596 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37828596 — Predictive Biomarker (PRD): Hormone receptor
Study 37829689 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 37830208 — Surrogate Endpoint (SUR): Blood pressure
Study 37830268 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 37830579 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 37830908 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37830944 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 37831074 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 37831074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37831682 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 37831941 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 37832571 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37832982 — Predictive Biomarker (PRD): EEF1A2 mRNA
Genes: EEF1A2; EEF1AL; STN
Study 37833387 — Predictive Biomarker (PRD): SLC20A1 mRNA
Genes: SLC20A1; GLVR1; PIT1
Study 37833640 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37833679 — Surrogate Endpoint (SUR): Serum potassium
Study 37833681 — Predictive Biomarker (PRD): MECP2 mRNA
Genes: MECP2
Study 37833681 — Predictive Biomarker (PRD): Cyclin-dependent kinase-like 5
Genes: CDKL5; STK9
Study 37833681 — Predictive Biomarker (PRD): FOXG1 mRNA
Genes: FOXG1; FKH2; FKHL1; FKHL2; FKHL3; FKHL4; FOXG1A; FOXG1B; FOXG1C
Study 37833799 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 37833799 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 37833799 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37837493 — Predictive Biomarker (PRD): PI3 mRNA
Genes: PI3; WAP3; WFDC14
Study 37837493 — Predictive Biomarker (PRD): S100A7 mRNA
Genes: S100A7; PSOR1; S100A7C
Study 37837493 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 37837629 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 37838323 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 37838686 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 37839434 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37839434 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 37839434 — Predictive Biomarker (PRD): TCFL5 mRNA
Genes: TCFL5; CHA; E2BP1
Study 37839707 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 37840134 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 37840134 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 37840134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37840530 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 37841423 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37841423 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37841423 — Predictive Biomarker (PRD): Hormone receptor
Study 37841873 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 37842200 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 37842323 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 37843478 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37843478 — Surrogate Endpoint (SUR): Blood pressure
Study 37843478 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37843637 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 37843637 — Surrogate Endpoint (SUR): Probing pocket depth
Study 37843637 — Surrogate Endpoint (SUR): Bacterial count
Study 37843770 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 37843770 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 37843772 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 37844137 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 37844519 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 37844838 — Predictive Biomarker (PRD): LEAP2 mRNA
Genes: LEAP2
Study 37844986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37845588 — Surrogate Endpoint (SUR): Blood pressure
Study 37845604 — Surrogate Endpoint (SUR): Blood pressure
Study 37845624 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37846607 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 37846664 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37846845 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 37847109 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 37847138 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 37847288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37847288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37847454 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 37847695 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 37848634 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 37848651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37848867 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37849628 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37850379 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 37850379 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37850681 — Predictive Biomarker (PRD): SLC6A8 mRNA
Genes: SLC6A8
Study 37851072 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study 37851128 — Surrogate Endpoint (SUR): Probing pocket depth
Study 37851297 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 37851488 — Safety Biomarker (SAF): BDNF
Study 37851732 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37852649 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37853427 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37853454 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37853485 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 37855026 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37855029 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 37855117 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 37855448 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 37855448 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 37855448 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37855706 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 37855754 — Surrogate Endpoint (SUR): Blood pressure
Study 37855754 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37855920 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 37855973 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 37856199 — Surrogate Endpoint (SUR): Blood pressure
Study 37857496 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37857496 — Surrogate Endpoint (SUR): Blood pressure
Study 37857528 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study 37857711 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37857766 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 37857766 — Surrogate Endpoint (SUR): Blood pressure
Study 37857766 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 37857939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37858007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37858132 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 37858132 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 37858184 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 37858195 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 37858195 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 37858195 — Monitoring Biomarker (MOI): Cell-free DNA
Study 37858195 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 37858328 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 37858724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 37858758 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37859672 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 37859748 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37859768 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study 37860278 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study 37860863 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 37860863 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37860863 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 37861407 — Predictive Biomarker (PRD): SLITRK6 mRNA
Genes: SLITRK6
Study 37862791 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 37862832 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37862832 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37862832 — Predictive Biomarker (PRD): Hormone receptor
Study 37863080 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 37863080 — Predictive Biomarker (PRD): Liver iron
Study 37863088 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 37863088 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 37863160 — Surrogate Endpoint (SUR): Bone mineral density
Study 37863398 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 37863608 — Surrogate Endpoint (SUR): Blood pressure
Study 37864152 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 37864156 — Surrogate Endpoint (SUR): Blood pressure
Study 37864209 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 37864209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2