TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32332634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34872511 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33205673 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 616173046 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 616173046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32631414 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32631414 — Monitoring Biomarker (MOI): Procalcitonin
Study 35241937 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 34867514 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35025757 — Safety Biomarker (SAF): Hyaluronic acid
Study 32052516 — Surrogate Endpoint (SUR): Blood pressure
Study 33978188 — Surrogate Endpoint (SUR): Blood pressure
Study 33120822 — Surrogate Endpoint (SUR): Blood pressure
Study 32841326 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 35720026 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34978388 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 34146511 — Predictive Biomarker (PRD): Anti-acetylcholine receptor antibody
Study 33326694 — Surrogate Endpoint (SUR): Bone mineral density
Study 35504197 — Surrogate Endpoint (SUR): Bone mineral density
Study 34120363 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33587407 — Surrogate Endpoint (SUR): Bone mineral density
Study 32341595 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 34263971 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 35496721 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 33794517 — Predictive Biomarker (PRD): AKR1C1 mRNA
Genes: AKR1C1; DDH; DDH1
Study 36356829 — Surrogate Endpoint (SUR): Blood pressure
Study 33894738 — Surrogate Endpoint (SUR): Blood pressure
Study 32276257 — Surrogate Endpoint (SUR): Bone mineral density
Study 32778471 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 35983532 — Monitoring Biomarker (MOI): Procalcitonin
Study 35983532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33380704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33380704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35771353 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 35762448 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 33564120 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 33564120 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 37745675 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32312010 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 32312010 — Safety Biomarker (SAF): Interleukin 1
Study 34687214 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 34687214 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 34687214 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 34687214 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 32853275 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34583525 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 36209084 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 36209084 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 36209084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36209084 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 36209084 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 36209084 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 36209084 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 35908457 — Surrogate Endpoint (SUR): Bone mineral density
Study 33758944 — Surrogate Endpoint (SUR): Blood pressure
Study 33758944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33481009 — Predictive Biomarker (PRD): FURIN mRNA
Genes: FURIN; FUR; PACE; PCSK3
Study 33481009 — Predictive Biomarker (PRD): SLC12A5 mRNA
Genes: SLC12A5; KCC2; KIAA1176
Study 32195805 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36482606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32447722 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 33113783 — Predictive Biomarker (PRD): TRPV4 mRNA
Genes: TRPV4; VRL2; VROAC
Study 33113783 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 35966245 — Predictive Biomarker (PRD): INVS mRNA
Genes: INVS; INV; NPHP2
Study 35084634 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 36155062 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 33781103 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 33124791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33124791 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33124791 — Surrogate Endpoint (SUR): Blood pressure
Study 35585570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 35585570 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34267185 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36042439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36042439 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 33960081 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 36260577 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36260577 — Surrogate Endpoint (SUR): Bone mineral density
Study 32444327 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32444327 — Surrogate Endpoint (SUR): Blood pressure
Study 32444327 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32444327 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34130017 — Predictive Biomarker (PRD): SDC1 mRNA
Genes: SDC1; SDC
Study 35073366 — Surrogate Endpoint (SUR): Bone mineral density
Study 33325403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34457094 — Surrogate Endpoint (SUR): Blood pressure
Study 32487263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32308012 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 33618392 — Surrogate Endpoint (SUR): Blood pressure
Study 32443329 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32718783 — Surrogate Endpoint (SUR): Blood pressure
Study 35238704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35238704 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 33241757 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33847758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34310400 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34498320 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 33962594 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32347885 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 32347885 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33829580 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 34820909 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34182189 — Surrogate Endpoint (SUR): Blood pressure
Study 32461554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32461554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32461554 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35839545 — Surrogate Endpoint (SUR): Blood pressure
Study 33525489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33525489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34575354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33403333 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 36125701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33657294 — Surrogate Endpoint (SUR): Serum creatinine
Study 35926542 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 35959346 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35959346 — Surrogate Endpoint (SUR): Blood pressure
Study 34813125 — Safety Biomarker (SAF): Reactive oxygen species
Study 33181634 — Surrogate Endpoint (SUR): Blood pressure
Study 32664175 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 32664175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32664175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33608045 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 33200257 — Surrogate Endpoint (SUR): Bone mineral density
Study 35393308 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 32197246 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 32513480 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32822216 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32822216 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 32681547 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 35012573 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 32034480 — Predictive Biomarker (PRD): CARM1 mRNA
Genes: CARM1; PRMT4
Study 32034480 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32034480 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CTNNB1 mRNA
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study 32381429 — Predictive Biomarker (PRD): ACOT2 mRNA
Genes: ACOT2; PTE2; PTE2A
Study 32381429 — Predictive Biomarker (PRD): CYP27A1 mRNA
Genes: CYP27A1; CYP27
Study 32381429 — Predictive Biomarker (PRD): ELOVL3 mRNA
Genes: ELOVL3; CIG30
Study 32381429 — Predictive Biomarker (PRD): FABP7 mRNA
Genes: FABP7; BLBP; FABPB; MRG
Study 32381429 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 32381429 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 32381429 — Predictive Biomarker (PRD): CFL1 mRNA
Genes: CFL1; CFL
Study 32381429 — Predictive Biomarker (PRD): EPHA2 mRNA
Genes: EPHA2; ECK
Study 32381429 — Predictive Biomarker (PRD): HRAS mRNA
Genes: HRAS; HRAS1
Study 32381429 — Predictive Biomarker (PRD): PER3 mRNA
Genes: PER3; GIG13
Study 34642756 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 32800653 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 32723679 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32522251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32522251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32973176 — Predictive Biomarker (PRD): FABP5 mRNA
Genes: FABP5
Study 32973176 — Predictive Biomarker (PRD): CRABP2 mRNA
Genes: CRABP2
Study 36056421 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 32237331 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 32237331 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32237331 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 36187125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36187125 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 36187125 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 36187125 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 36187125 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 36187125 — Predictive Biomarker (PRD): Small-inducible cytokine A11
Genes: CCL11; SCYA11
Study 33958525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33958525 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 32794023 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35486840 — Safety Biomarker (SAF): BDNF
Study 35486840 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 33369763 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 32950115 — Surrogate Endpoint (SUR): Blood pressure
Study 33260376 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 33253237 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 35599514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34736509 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 33827652 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32822775 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 32822775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33413508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33413508 — Safety Biomarker (SAF): Interleukin 1
Study 35513244 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 35618742 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33735798 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33465455 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 33465455 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 32663278 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32663278 — Surrogate Endpoint (SUR): Blood pressure
Study 33813855 — Surrogate Endpoint (SUR): Blood pressure
Study 33471625 — Predictive Biomarker (PRD): 40S ribosomal protein S6
Genes: RPS6; OK/SW-cl.2
Study 35088499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34961705 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 33603039 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33603039 — Safety Biomarker (SAF): BDNF
Study 36206636 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 34995536 — Monitoring Biomarker (MOI): HBV DNA
Study 36030815 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 32979724 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 32956419 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34473018 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 33211166 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 33017662 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 33305513 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34148852 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 35912711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36159368 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 36263035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33839603 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32826103 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33954198 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35614292 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 35614292 — Surrogate Endpoint (SUR): Sperm parameters
Study 32188386 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 32188386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32188386 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32438719 — Surrogate Endpoint (SUR): Blood pressure
Study 35894768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35894768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35894768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34284099 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 34541864 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 35552458 — Predictive Biomarker (PRD): MC1R mRNA
Genes: MC1R; MSHR
Study 32478917 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32478917 — Surrogate Endpoint (SUR): Serum creatinine
Study 34052593 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 35244702 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study 34074289 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 34074289 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 36008722 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 33550716 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 33149899 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35255929 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 32295442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32295442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32295442 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 32295442 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32295442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34018381 — Surrogate Endpoint (SUR): Blood pressure
Study 33669520 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 32092060 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32092060 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 32092060 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 32092060 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 32092060 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33022653 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35913798 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 36316798 — Surrogate Endpoint (SUR): Blood pressure
Study 36316798 — Surrogate Endpoint (SUR): Serum calcium
Study 33575961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33575961 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34085478 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 32768871 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 32768871 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 35129010 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 36108818 — Predictive Biomarker (PRD): LHB mRNA
Genes: LHB
Study 34228856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34613575 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 34613575 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 33257495 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 32481305 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35718313 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 34035312 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35745176 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22