TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33876196 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 33619120 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32464435 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 32892235 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 32609756 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33562394 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 34558847 — Safety Biomarker (SAF): Type I cytoskeletal 18 Keratin
Genes: KRT18; CYK18; PIG46
Study 34558847 — Safety Biomarker (SAF): Glutamate dehydrogenase
Study 34907265 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34907265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34907265 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 34907265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36315274 — Surrogate Endpoint (SUR): Blood pressure
Study 32646638 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35360482 — Surrogate Endpoint (SUR): Serum testosterone
Study 35560310 — Safety Biomarker (SAF): Reactive oxygen species
Study 34023008 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 34023008 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 34023008 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study 34001166 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 33932804 — Surrogate Endpoint (SUR): Blood pressure
Study 33040829 — Predictive Biomarker (PRD): TPT1 mRNA
Genes: TPT1
Study 33040829 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 34900568 — Surrogate Endpoint (SUR): Blood pressure
Study 36304175 — Surrogate Endpoint (SUR): Blood pressure
Study 36304175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34803922 — Surrogate Endpoint (SUR): Blood pressure
Study 616062932 — Predictive Biomarker (PRD): RAD51AP1 mRNA
Genes: RAD51AP1; PIR51
Study 33016996 — Surrogate Endpoint (SUR): Blood pressure
Study 34344482 — Surrogate Endpoint (SUR): Bone mineral density
Study 32475902 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33769243 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33769243 — Predictive Biomarker (PRD): GPX4 mRNA
Genes: GPX4
Study 33769243 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33769243 — Predictive Biomarker (PRD): PRDX1 mRNA
Genes: PRDX1; PAGA; PAGB; TDPX2
Study 33769243 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 33769243 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 32902561 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 35747142 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34962665 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 34962665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35818255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34416294 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 616222542 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 616222542 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 35672455 — Surrogate Endpoint (SUR): Blood pressure
Study 32737420 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32737420 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32737420 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32969531 — Surrogate Endpoint (SUR): Blood pressure
Study 34959861 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34959861 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 35836365 — Pharmacodynamic Biomarker (PDY): Dermal blood flow
Study 32290852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33640422 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33640422 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 32555927 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33804123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33734306 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33734306 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35501626 — Surrogate Endpoint (SUR): Blood pressure
Study 33270531 — Predictive Biomarker (PRD): APEX1 mRNA
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 32869659 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32869659 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34903696 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 34903696 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32506135 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33586539 — Surrogate Endpoint (SUR): Blood pressure
Study 32275191 — Safety Biomarker (SAF): Interleukin 1
Study 32275191 — Surrogate Endpoint (SUR): Blood pressure
Study 35896969 — Surrogate Endpoint (SUR): Blood pressure
Study 32101262 — Surrogate Endpoint (SUR): Blood pressure
Study 34275501 — Surrogate Endpoint (SUR): Serum calcium
Study 36195338 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 34751928 — Predictive Biomarker (PRD): TAAR1 mRNA
Genes: TAAR1; TA1; TAR1; TRAR1
Study 34751928 — Safety Biomarker (SAF): DRD2
Study 34105866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34082176 — Surrogate Endpoint (SUR): Serum creatinine
Study 32773737 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34128083 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 36368677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34006044 — Monitoring Biomarker (MOI): Procalcitonin
Study 34006044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32902207 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 32902207 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 33991471 — Surrogate Endpoint (SUR): Blood pressure
Study 35379247 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33335310 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 32867830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33543797 — Predictive Biomarker (PRD): OMG mRNA
Genes: OMG; OMGP
Study 33248560 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 36313769 — Predictive Biomarker (PRD): IGF2BP2 mRNA
Genes: IGF2BP2; IMP2; VICKZ2
Study 36313769 — Predictive Biomarker (PRD): DPYSL5 mRNA
Genes: DPYSL5; CRMP5; ULIP6
Study 36313769 — Predictive Biomarker (PRD): PDHX mRNA
Genes: PDHX; PDX1
Study 36313769 — Predictive Biomarker (PRD): GCKR mRNA
Genes: GCKR
Study 36313769 — Predictive Biomarker (PRD): COBLL1 mRNA
Genes: COBLL1; KIAA0977
Study 36313769 — Predictive Biomarker (PRD): SLC17A9 mRNA
Genes: SLC17A9; C20orf59
Study 36313769 — Predictive Biomarker (PRD): FOXA2 mRNA
Genes: FOXA2; HNF3B; TCF3B
Study 36313769 — Predictive Biomarker (PRD): GLIS3 mRNA
Genes: GLIS3; ZNF515
Study 36313769 — Predictive Biomarker (PRD): WARS1 mRNA
Genes: WARS1; IFI53; WARS; WRS
Study 36313769 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 36313769 — Predictive Biomarker (PRD): CDKAL1 mRNA
Genes: CDKAL1
Study 34602386 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 33602945 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36364765 — Surrogate Endpoint (SUR): Serum uric acid
Study 34428832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36005837 — Surrogate Endpoint (SUR): Blood pressure
Study 36005837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34047697 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33560411 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 32809002 — Surrogate Endpoint (SUR): Blood pressure
Study 32809002 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33704530 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 33704530 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 33704530 — Predictive Biomarker (PRD): NELFCD mRNA
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 33039693 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 33002704 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 36059000 — Predictive Biomarker (PRD): Chromodomain-helicase-DNA-binding protein 1
Genes: CHD1
Study 34363051 — Surrogate Endpoint (SUR): Blood pressure
Study 33582687 — Surrogate Endpoint (SUR): Blood pressure
Study 33239951 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34691212 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 32777383 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 34086194 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 34086194 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 32187464 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36471427 — Surrogate Endpoint (SUR): Blood pressure
Study 36245373 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 36245373 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 35465733 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35465733 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 35465733 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35465733 — Predictive Biomarker (PRD): Hormone receptor
Study 35465733 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 33264163 — Predictive Biomarker (PRD): SVOP mRNA
Genes: SVOP
Study 35685522 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32783912 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35472391 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33183969 — Predictive Biomarker (PRD): Hormone receptor
Study 32645162 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34789340 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 36403976 — Surrogate Endpoint (SUR): Serum creatinine
Study 36403976 — Surrogate Endpoint (SUR): Serum uric acid
Study 32596393 — Surrogate Endpoint (SUR): Serum creatinine
Study 32596393 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34044760 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 36002368 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32613718 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 32613718 — Surrogate Endpoint (SUR): Serum uric acid
Study 33864832 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 32829105 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 35742443 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33086234 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32469184 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 35820835 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32805700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35014061 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 34514890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34514890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34514890 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33755846 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 33746023 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34435469 — Surrogate Endpoint (SUR): Blood pressure
Study 34435469 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32076569 — Surrogate Endpoint (SUR): Blood pressure
Study 33368960 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32389013 — Predictive Biomarker (PRD): C1QA mRNA
Genes: C1QA
Study 32389013 — Predictive Biomarker (PRD): C1QB mRNA
Genes: C1QB
Study 32389013 — Predictive Biomarker (PRD): C1QC mRNA
Genes: C1QC; C1QG
Study 32389013 — Predictive Biomarker (PRD): C1R mRNA
Genes: C1R
Study 32389013 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 32389013 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 32389013 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 32389013 — Predictive Biomarker (PRD): ITGAM mRNA
Genes: ITGAM; CD11B; CR3A
Study 32389013 — Predictive Biomarker (PRD): ITGAX mRNA
Genes: ITGAX; CD11C
Study 32164785 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32164785 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32164785 — Predictive Biomarker (PRD): Hormone receptor
Study 35524006 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 32326806 — Surrogate Endpoint (SUR): Blood pressure
Study 32591250 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 34025637 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 36327047 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 33466131 — Safety Biomarker (SAF): Hyaluronic acid
Study 32111230 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 35023557 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35332040 — Surrogate Endpoint (SUR): Blood pressure
Study 32384727 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32384727 — Surrogate Endpoint (SUR): Blood pressure
Study 32635877 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32948867 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 32948867 — Surrogate Endpoint (SUR): Blood pressure
Study 32854834 — Surrogate Endpoint (SUR): Serum creatinine
Study 35458181 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 34387520 — Surrogate Endpoint (SUR): Serum calcium
Study 33941219 — Safety Biomarker (SAF): Interleukin 1
Study 33941219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34202464 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 35715946 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34424530 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 36208853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36208853 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 36208853 — Safety Biomarker (SAF): Interleukin 1
Study 32979074 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 34082251 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34082251 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34297338 — Surrogate Endpoint (SUR): Serum sodium
Study 34810217 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34810217 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34810217 — Predictive Biomarker (PRD): Hormone receptor
Study 33085058 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34261793 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34526397 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 33337698 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 33355713 — Surrogate Endpoint (SUR): Blood pressure
Study 32217612 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34076752 — Surrogate Endpoint (SUR): Serum creatinine
Study 36194846 — Surrogate Endpoint (SUR): Blood pressure
Study 33095682 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33780276 — Surrogate Endpoint (SUR): Serum testosterone
Study 36660974 — Surrogate Endpoint (SUR): Bone mineral density
Study 32616309 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 32616309 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 32616309 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33308348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35785139 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35785139 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 33306634 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 33306634 — Safety Biomarker (SAF): Reactive oxygen species
Study 35791020 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 34545997 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34545997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34545997 — Predictive Biomarker (PRD): TAFA5 mRNA
Genes: TAFA5; FAM19A5; UNQ5208/PRO34524
Study 32481584 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32481584 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 32481584 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36078292 — Predictive Biomarker (PRD): CPOX mRNA
Genes: CPOX; CPO; CPX
Study 32552857 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 34422261 — Surrogate Endpoint (SUR): Blood pressure
Study 34589205 — Surrogate Endpoint (SUR): Blood pressure
Study 33377701 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 33291088 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34211322 — Surrogate Endpoint (SUR): Blood pressure
Study 34211322 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34211322 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35459947 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 35459947 — Safety Biomarker (SAF): Hyaluronic acid
Study 32590944 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 34647981 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 34277985 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33013880 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 32164314 — Surrogate Endpoint (SUR): Blood pressure
Study 34275259 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34275259 — Surrogate Endpoint (SUR): Blood pressure
Study 33336698 — Predictive Biomarker (PRD): TP53INP2 mRNA
Genes: TP53INP2; C20orf110; DOR; PINH
Study 33336698 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33336698 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35664468 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 35664468 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 33269819 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33269819 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 34193072 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36395435 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 36395435 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32459600 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 35090033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35090033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34409538 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 34409538 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study 34688374 — Predictive Biomarker (PRD): Microsatellite instability
Study 35352134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35352134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35142162 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35142162 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 35142162 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 35142162 — Predictive Biomarker (PRD): APOBEC3B mRNA
Genes: APOBEC3B
Study 35620203 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 35620203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35620203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1