TrialPanorama/TrialPanorama-database huggingface dataset:
Study 36924196 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 36924288 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36924606 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36925644 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36925786 — Predictive Biomarker (PRD): HRC mRNA
Genes: HRC; HCP
Study 36926939 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36927409 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 36927420 — Monitoring Biomarker (MOI): HBV DNA
Study 36927455 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 36927455 — Predictive Biomarker (PRD): STAT2 mRNA
Genes: STAT2
Study 36927455 — Predictive Biomarker (PRD): IFNAR1 mRNA
Genes: IFNAR1; IFNAR
Study 36927455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36927496 — Surrogate Endpoint (SUR): Blood pressure
Study 36927527 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 36927527 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36927527 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 36927585 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 36927595 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 36927754 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36927977 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 36927977 — Safety Biomarker (SAF): Platelet to lymphocyte
Study 36928072 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36928395 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 36928395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36928705 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36928705 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 36928818 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36928818 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 36928921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36928921 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 36929216 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36929533 — Surrogate Endpoint (SUR): Serum asparaginase
Study 36930042 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 36930857 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 36931261 — Predictive Biomarker (PRD): TLE6 mRNA
Genes: TLE6
Study 36931261 — Predictive Biomarker (PRD): NLRP2 mRNA
Genes: NLRP2; NALP2; NBS1; PAN1; PYPAF2
Study 36931261 — Predictive Biomarker (PRD): NLRP5 mRNA
Genes: NLRP5; MATER; NALP5
Study 36931261 — Predictive Biomarker (PRD): NLRP7 mRNA
Genes: NLRP7; NALP7; NOD12; PYPAF3
Study 36931680 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 36931680 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 36931693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36932356 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 36932356 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36932361 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 36932416 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 36933080 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study 36933552 — Surrogate Endpoint (SUR): Blood pressure
Study 36933755 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 36933790 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 36934257 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 36934327 — Predictive Biomarker (PRD): TNFSF14 mRNA
Genes: TNFSF14; HVEML; LIGHT; UNQ391/PRO726
Study 36934327 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 36934327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36934668 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36934668 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36934668 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36935288 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36935288 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 36936551 — Safety Biomarker (SAF): XRCC1
Genes: RCC
Study 36936918 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36936952 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 36937912 — Predictive Biomarker (PRD): P4HB mRNA
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 36937990 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 36938380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36938380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36939067 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36939629 — Predictive Biomarker (PRD): MICB mRNA
Genes: MICB; PERB11.2
Study 36939774 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 36939815 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 36940261 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 36941155 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36941155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36941402 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 36941402 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36942533 — Surrogate Endpoint (SUR): Blood pressure
Study 36943254 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36943254 — Safety Biomarker (SAF): Interleukin 1
Study 36943669 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36943907 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 36943907 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36944142 — Surrogate Endpoint (SUR): Bone mineral density
Study 36944694 — Safety Biomarker (SAF): IL-6 and IL-10
Study 36944848 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36945034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36945037 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 36945037 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 36945037 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 36945037 — Predictive Biomarker (PRD): CD244 mRNA
Genes: CD244; 2B4
Study 36945579 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 36945579 — Surrogate Endpoint (SUR): Serum creatinine
Study 36945773 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 36945773 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 36946293 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 36946321 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 36946440 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36946603 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 36946749 — Safety Biomarker (SAF): Reactive oxygen species
Study 36947201 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 36947521 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 36947713 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 36948246 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 36948325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36948505 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 36948505 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 36948505 — Predictive Biomarker (PRD): PSCA mRNA
Genes: PSCA; UNQ206/PRO232
Study 36949155 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 36949155 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 36949248 — Predictive Biomarker (PRD): TAAR1 mRNA
Genes: TAAR1; TA1; TAR1; TRAR1
Study 36949284 — Surrogate Endpoint (SUR): Blood pressure
Study 36949485 — Surrogate Endpoint (SUR): Blood pressure
Study 36949953 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 36950415 — Surrogate Endpoint (SUR): Blood pressure
Study 36950450 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 36950857 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study 36950857 — Surrogate Endpoint (SUR): Bone mineral density
Study 36951052 — Surrogate Endpoint (SUR): Blood pressure
Study 36951168 — Safety Biomarker (SAF): UGT1A1
Genes: UGT1A
Study 36951168 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study 36951827 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 36951827 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 36951827 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36951834 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 36951958 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36952231 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36958364 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 36958365 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36958470 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 36958470 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 36958470 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 36958720 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 36958940 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 36958969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36958969 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36958969 — Surrogate Endpoint (SUR): Blood pressure
Study 36958998 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 36959289 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 36959289 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 36959584 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36959634 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 36959634 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 36959658 — Surrogate Endpoint (SUR): Blood pressure
Study 36959953 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 36960054 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 36960054 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study 36960087 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36960762 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 36961591 — Surrogate Endpoint (SUR): Probing pocket depth
Study 36962510 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36962514 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 36962953 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36963127 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 36963200 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36963417 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 36963502 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 36963502 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 36963502 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36963502 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 36963852 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36964191 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 36964191 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36964191 — Predictive Biomarker (PRD): XRCC2 mRNA
Genes: XRCC2
Study 36964191 — Predictive Biomarker (PRD): BARD1 mRNA
Genes: BARD1
Study 36964191 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 36964626 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 36965105 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 36965866 — Monitoring Biomarker (MOI): Cell-free DNA
Study 36966905 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36967158 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 36967681 — Predictive Biomarker (PRD): CDHR3 mRNA
Genes: CDHR3; CDH28
Study 36967681 — Predictive Biomarker (PRD): GSDMA mRNA
Genes: GSDMA; GSDM; GSDM1; FKSG9
Study 36967681 — Predictive Biomarker (PRD): GSDMB mRNA
Genes: GSDMB; GSDML; PP4052; PRO2521
Study 36967681 — Predictive Biomarker (PRD): IKZF3 mRNA
Genes: IKZF3; ZNFN1A3
Study 36967681 — Predictive Biomarker (PRD): ORMDL3 mRNA
Genes: ORMDL3
Study 36967714 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 36967843 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 36968218 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 36968629 — Surrogate Endpoint (SUR): Blood pressure
Study 36969063 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 36969244 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 36969338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 36969338 — Safety Biomarker (SAF): Reactive oxygen species
Study 36969747 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 36969745 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36969889 — Monitoring Biomarker (MOI): HBV DNA
Study 36970054 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 36970054 — Monitoring Biomarker (MOI): Cell-free DNA
Study 36970056 — Predictive Biomarker (PRD): CDC7 mRNA
Genes: CDC7; CDC7L1
Study 36970055 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 36970876 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 36970876 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 36971560 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 36972026 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 36972026 — Predictive Biomarker (PRD): Microsatellite instability
Study 36972140 — Predictive Biomarker (PRD): SMIM29 mRNA
Genes: SMIM29; C6orf1; LBH
Study 36972491 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 36972796 — Predictive Biomarker (PRD): CD1C mRNA
Genes: CD1C
Study 36972796 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 36972800 — Surrogate Endpoint (SUR): Blood pressure
Study 36972964 — Predictive Biomarker (PRD): NISCH mRNA
Genes: NISCH; IRAS; KIAA0975
Study 36972972 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 36973671 — Surrogate Endpoint (SUR): Blood pressure
Study 36973671 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36973954 — Safety Biomarker (SAF): Interleukin 1
Study 36974122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36974462 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 36974638 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 36975019 — Surrogate Endpoint (SUR): Blood pressure
Study 36975201 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 36975207 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 36975308 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 36975369 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 36976651 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 36976651 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 36976655 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36977289 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 36977292 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 36977960 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study 36977960 — Predictive Biomarker (PRD): NR4A3 mRNA
Genes: NR4A3; CHN; CSMF; MINOR; NOR1; TEC
Study 36977973 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36977973 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 36978045 — Surrogate Endpoint (SUR): Blood pressure
Study 36978071 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36978080 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 36978128 — Predictive Biomarker (PRD): AKAP17A mRNA
Genes: AKAP17A; CXYorf3; DXYS155E; SFRS17A; XE7
Study 36978128 — Pharmacodynamic Biomarker (PDY): CD99 antigen
Genes: CD99; MIC2; MIC2X; MIC2Y
Study 36978128 — Predictive Biomarker (PRD): DHRSX mRNA
Genes: DHRSX; CXorf11; DHRS5X; SDR46C1; SDR7C6; UNQ6508/PRO21433
Study 36978128 — Predictive Biomarker (PRD): EIF2S3 mRNA
Genes: EIF2S3; EIF2G
Study 36978128 — Predictive Biomarker (PRD): GTPBP6 mRNA
Genes: GTPBP6; PGPL
Study 36978128 — Predictive Biomarker (PRD): PUDP mRNA
Genes: PUDP; DXF68S1E; FAM16AX; GS1; HDHD1; HDHD1A
Study 36978128 — Predictive Biomarker (PRD): SLC25A6 mRNA
Genes: SLC25A6; AAC3; ANT3; CDABP0051
Study 36979982 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 36987384 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 36987384 — Predictive Biomarker (PRD): Microsatellite instability
Study 36987836 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 36987836 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 36987861 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 36987861 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36987929 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36988824 — Surrogate Endpoint (SUR): Probing pocket depth
Study 36989829 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 36989829 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 36989884 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 36989884 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36990211 — Predictive Biomarker (PRD): AKR1C3 mRNA
Genes: AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
Study 36990211 — Predictive Biomarker (PRD): TCL1A mRNA
Genes: TCL1A; TCL1
Study 36990214 — Predictive Biomarker (PRD): ACP3 mRNA
Genes: ACP3; ACPP
Study 36990481 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 36990493 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 36990493 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 36990610 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study 36990622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 36990622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 36991169 — Predictive Biomarker (PRD): SGK2 mRNA
Genes: SGK2
Study 36991390 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 36991390 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 36991396 — Surrogate Endpoint (SUR): Blood pressure
Study 36992541 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 36992761 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 36992863 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36992863 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36992863 — Predictive Biomarker (PRD): Hormone receptor
Study 36993363 — Predictive Biomarker (PRD): GLP1R mRNA
Genes: GLP1R
Study 36993880 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 36994730 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 36995690 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 36995872 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36996322 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36996322 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 36996322 — Predictive Biomarker (PRD): CCDC6 mRNA
Genes: CCDC6; D10S170; TST1
Study 36996322 — Predictive Biomarker (PRD): NCOA4 mRNA
Genes: NCOA4; ARA70; ELE1; RFG
Study 36996322 — Predictive Biomarker (PRD): EML4 mRNA
Genes: EML4; C2orf2; EMAPL4
Study 36996322 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 36996322 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 36996325 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 36996325 — Monitoring Biomarker (MOI): Cell-free DNA
Study 36997069 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 36997799 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 36997822 — Predictive Biomarker (PRD): MUC2 mRNA
Genes: MUC2; SMUC
Study 36997822 — Predictive Biomarker (PRD): MUC3A mRNA
Genes: MUC3A; MUC3
Study 36998287 — Surrogate Endpoint (SUR): Blood pressure