TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33967615 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 34958142 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34958142 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34958142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34958142 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35131378 — Surrogate Endpoint (SUR): Blood pressure
Study 35024794 — Predictive Biomarker (PRD): TMIE mRNA
Genes: TMIE
Study 36282079 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 36282079 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 36282079 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36282079 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35268057 — Surrogate Endpoint (SUR): Blood pressure
Study 35268057 — Surrogate Endpoint (SUR): Serum triglycerides
Study 35268057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34606579 — Surrogate Endpoint (SUR): Blood pressure
Study 33454989 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 33454989 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 33730804 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 35771264 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35771264 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35771264 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 34288808 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 34288808 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34288808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 35301883 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35452419 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32949505 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 34739648 — Surrogate Endpoint (SUR): Blood pressure
Study 32943015 — Surrogate Endpoint (SUR): Blood pressure
Study 34530894 — Surrogate Endpoint (SUR): Blood pressure
Study 35690556 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34396571 — Monitoring Biomarker (MOI): HBV DNA
Study 34229888 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34621450 — Surrogate Endpoint (SUR): Blood pressure
Study 35135006 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 35135006 — Predictive Biomarker (PRD): TAS1R3 mRNA
Genes: TAS1R3; T1R3; TR3
Study 35135006 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 34256114 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34910554 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 32060099 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35113435 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 32892320 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32745555 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32745555 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 32745555 — Predictive Biomarker (PRD): KMT2D mRNA
Genes: KMT2D; ALR; MLL2; MLL4
Study 32745555 — Predictive Biomarker (PRD): XIAP mRNA
Genes: XIAP; API3; BIRC4; IAP3
Study 32745555 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34653515 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34653515 — Predictive Biomarker (PRD): CCRL2 mRNA
Genes: CCRL2; CCR11; CCR6; CKRX; CRAM; HCR
Study 33808849 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33808849 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 32450253 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 32450253 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 35416182 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 35677636 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35677636 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35465007 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35465007 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 33301009 — Surrogate Endpoint (SUR): Blood pressure
Study 35643988 — Safety Biomarker (SAF): Hyaluronic acid
Study 35718807 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33745609 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33745609 — Safety Biomarker (SAF): BDNF
Study 33527137 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33527137 — Predictive Biomarker (PRD): Hormone receptor
Study 33931900 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35723751 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 34426469 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 35395555 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 32147256 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 34311336 — Surrogate Endpoint (SUR): Blood pressure
Study 32174033 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 34790138 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 33090380 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 33785385 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 35322843 — Surrogate Endpoint (SUR): Blood pressure
Study 32675750 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 34131001 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 35366806 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34221185 — Predictive Biomarker (PRD): TENM1 mRNA
Genes: TENM1; ODZ1; TNM1
Study 34221185 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 34221185 — Predictive Biomarker (PRD): APOD mRNA
Genes: APOD
Study 34221185 — Predictive Biomarker (PRD): F12 mRNA
Genes: F12
Study 34147867 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36282407 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study 32046537 — Surrogate Endpoint (SUR): Blood pressure
Study 34626578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33055462 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33055462 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33055462 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35212924 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35212924 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 35212924 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 35212924 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 35346115 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 35150142 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 35645781 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 35645781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35645781 — Safety Biomarker (SAF): BDNF
Study 35645781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33189655 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 35523943 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 35045567 — Surrogate Endpoint (SUR): Bone mineral density
Study 34029455 — Surrogate Endpoint (SUR): Serum testosterone
Study 34029455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35965962 — Surrogate Endpoint (SUR): Blood pressure
Study 36470077 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33635568 — Surrogate Endpoint (SUR): Blood pressure
Study 33819615 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 33819615 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 34744048 — Predictive Biomarker (PRD): PORCN mRNA
Genes: PORCN; MG61; PORC; PPN
Study 33592841 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 34982486 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34682669 — Predictive Biomarker (PRD): REG1A mRNA
Genes: REG1A; PSPS; PSPS1; REG
Study 32907591 — Safety Biomarker (SAF): IL-6 and IL-10
Study 32907591 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 34879448 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 35756424 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35357350 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 32016387 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32016387 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 34826022 — Predictive Biomarker (PRD): FTL mRNA
Genes: FTL
Study 35157830 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35157830 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 35157830 — Predictive Biomarker (PRD): MRPL36 mRNA
Genes: MRPL36; BRIP1
Study 35157830 — Predictive Biomarker (PRD): BARD1 mRNA
Genes: BARD1
Study 35157830 — Predictive Biomarker (PRD): CHEK1 mRNA
Genes: CHEK1; CHK1
Study 35157830 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study 35157830 — Predictive Biomarker (PRD): FANCL mRNA
Genes: FANCL; PHF9
Study 35157830 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study 35157830 — Predictive Biomarker (PRD): PPP2R2A mRNA
Genes: PPP2R2A
Study 35157830 — Predictive Biomarker (PRD): RAD51B mRNA
Genes: RAD51B; RAD51L1; REC2
Study 35157830 — Predictive Biomarker (PRD): RAD51C mRNA
Genes: RAD51C; RAD51L2
Study 32964918 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32745306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32298202 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 34082177 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35505379 — Surrogate Endpoint (SUR): Blood pressure
Study 35209851 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33575950 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 34356647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 616996472 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 35553192 — Surrogate Endpoint (SUR): Blood pressure
Study 32014029 — Surrogate Endpoint (SUR): Blood pressure
Study 33631359 — Surrogate Endpoint (SUR): Bone mineral density
Study 33140199 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 35489024 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33743851 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 33743851 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 35538754 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33417699 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33417699 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 32209015 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 35642463 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34898136 — Surrogate Endpoint (SUR): Blood pressure
Study 35780390 — Surrogate Endpoint (SUR): Blood pressure
Study 32560724 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 32560724 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33427969 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33427969 — Surrogate Endpoint (SUR): Blood pressure
Study 36300713 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 33247722 — Safety Biomarker (SAF): Reactive oxygen species
Study 33247722 — Surrogate Endpoint (SUR): Blood pressure
Study 36235571 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 32396288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34107968 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33036058 — Safety Biomarker (SAF): Hyaluronic acid
Study 33189807 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 36029727 — Surrogate Endpoint (SUR): Blood pressure
Study 32008370 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 34114408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32539805 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 35465002 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33847098 — Safety Biomarker (SAF): Calbindin
Genes: CALB1; CAB27
Study 33847098 — Predictive Biomarker (PRD): CALB1 mRNA
Genes: CALB1; CAB27
Study 35709412 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 34060937 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 36185085 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36185085 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36185085 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 36185085 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 36185085 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 36185085 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32301701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32301701 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35794366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36855259 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33108521 — Safety Biomarker (SAF): Bacteroidetes phylum
Study 35967369 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 35967369 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 35967369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33047859 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 33047859 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 34853380 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 33972129 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 32521325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32895343 — Surrogate Endpoint (SUR): Blood pressure
Study 33989234 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32702169 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 32819390 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 34171133 — Surrogate Endpoint (SUR): Blood pressure
Study 36180886 — Predictive Biomarker (PRD): ATG7 mRNA
Genes: ATG7; APG7L
Study 36180886 — Predictive Biomarker (PRD): BACH2 mRNA
Genes: BACH2
Study 36180886 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 36180886 — Predictive Biomarker (PRD): DHCR24 mRNA
Genes: DHCR24; KIAA0018
Study 36180886 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 36040766 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33485703 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 33485703 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 33485703 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 33485703 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 35341328 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 34704354 — Surrogate Endpoint (SUR): Blood pressure
Study 32003833 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33546942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33115598 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32244628 — Surrogate Endpoint (SUR): Blood pressure
Study 33183032 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34621044 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33471640 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34081111 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34028359 — Surrogate Endpoint (SUR): Bone mineral density
Study 34028359 — Surrogate Endpoint (SUR): Blood pressure
Study 33677411 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 32990919 — Monitoring Biomarker (MOI): HBV DNA
Study 34052096 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 35987472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33177818 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32426884 — Surrogate Endpoint (SUR): Blood pressure
Study 32426884 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36258217 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35635326 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 35635326 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32556157 — Monitoring Biomarker (MOI): HBV DNA
Study 32443306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32443306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32443306 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 32713349 — Surrogate Endpoint (SUR): Blood pressure
Study 35306123 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 33234633 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 34672950 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 35839558 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 35583273 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 34937855 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35941737 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35941737 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 35941737 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 33714741 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34732139 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 32457071 — Safety Biomarker (SAF): DRD2
Study 33933112 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32830332 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 32336721 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32336721 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 35770587 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 35770587 — Surrogate Endpoint (SUR): Blood pressure
Study 35770587 — Safety Biomarker (SAF): Reactive oxygen species
Study 35777058 — Surrogate Endpoint (SUR): Blood pressure
Study 35016790 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33112463 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 32907801 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33942350 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 32579773 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 32875698 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 32023931 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 33836651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33836651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32517390 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 35598122 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 35458108 — Surrogate Endpoint (SUR): Blood pressure
Study 34464517 — Surrogate Endpoint (SUR): Blood pressure
Study 32902102 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 34878659 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34542079 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 33999650 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34199645 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1