TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35256899 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34235978 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 36187334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36187334 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36187334 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36187334 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 36187334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36187334 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32051025 — Surrogate Endpoint (SUR): Blood pressure
Study 33027708 — Predictive Biomarker (PRD): CRHR1 mRNA
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 33027708 — Predictive Biomarker (PRD): CRHR2 mRNA
Genes: CRHR2; CRF2R; CRH2R
Study 33027708 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 33027708 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 33027708 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 33027708 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 35018760 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36314172 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 34620199 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34620199 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34254976 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34254976 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 33867497 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 32297719 — Surrogate Endpoint (SUR): Blood pressure
Study 37714408 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 37714408 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33581721 — Surrogate Endpoint (SUR): Blood pressure
Study 34077291 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 34077291 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35108470 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34156534 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 33872982 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 33872982 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34480657 — Surrogate Endpoint (SUR): Serum sodium
Study 34480657 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35803640 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33602588 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 33590342 — Surrogate Endpoint (SUR): Blood pressure
Study 35704218 — Surrogate Endpoint (SUR): Serum calcium
Study 33427749 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 36105936 — Monitoring Biomarker (MOI): Procalcitonin
Study 36105936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32453377 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 35529427 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 33326576 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 33096556 — Predictive Biomarker (PRD): FUT2 mRNA
Genes: FUT2; SEC2
Study 36374502 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 36374502 — Surrogate Endpoint (SUR): Blood pressure
Study 35132039 — Surrogate Endpoint (SUR): Blood pressure
Study 32246706 — Surrogate Endpoint (SUR): Serum creatinine
Study 33307409 — Predictive Biomarker (PRD): SNRPB mRNA
Genes: SNRPB; COD; SNRPB1
Study 33307409 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 33307409 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 35253564 — Surrogate Endpoint (SUR): Blood pressure
Study 35094848 — Safety Biomarker (SAF): APC
Genes: DP2; DP3; DP2.5; PPP1R46
Study 34018365 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 34018365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34018365 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 34018365 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34018365 — Safety Biomarker (SAF): Reactive oxygen species
Study 34177646 — Surrogate Endpoint (SUR): Blood pressure
Study 36164417 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36164417 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 36164417 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33252564 — Predictive Biomarker (PRD): HHEX mRNA
Genes: HHEX; HEX; PRH; PRHX
Study 35595817 — Predictive Biomarker (PRD): VSNL1 mRNA
Genes: VSNL1; VISL1
Study 35595817 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 34218304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34218304 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 34218304 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 34675150 — Safety Biomarker (SAF): Hyaluronic acid
Study 32475277 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 32475277 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 32475277 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32475277 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 32475277 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 32475277 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 32041613 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32539815 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 32539815 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 32539815 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 33843820 — Safety Biomarker (SAF): BDNF
Study 35640916 — Surrogate Endpoint (SUR): Blood pressure
Study 33766992 — Predictive Biomarker (PRD): 14-3-3 protein sigma
Genes: SFN; HME1
Study 34389506 — Predictive Biomarker (PRD): FIP1L1 mRNA
Genes: FIP1L1; FIP1; RHE
Study 32084562 — Surrogate Endpoint (SUR): Bone mineral density
Study 34239935 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34875625 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 33080934 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 35916800 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35916800 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35916800 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32380463 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 34420942 — Predictive Biomarker (PRD): P2RY12 mRNA
Genes: P2RY12; HORK3
Study 36482103 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 36069479 — Surrogate Endpoint (SUR): Bone mineral density
Study 34537624 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 34858513 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32538005 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 32538005 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 35379469 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 33403878 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 32651161 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32651161 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32651161 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 32651161 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 35572853 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 35572853 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 35572853 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35572853 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34420980 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34979943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34979943 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 32836220 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32836220 — Predictive Biomarker (PRD): VEGFB mRNA
Genes: VEGFB; VRF
Study 32836220 — Predictive Biomarker (PRD): VEGFC mRNA
Genes: VEGFC
Study 32836220 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 32836220 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34011351 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 35193165 — Surrogate Endpoint (SUR): Blood pressure
Study 33303654 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 33023491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33023491 — Safety Biomarker (SAF): Interleukin 1
Study 33023491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32818625 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 35700594 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34303491 — Surrogate Endpoint (SUR): Blood pressure
Study 35727442 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 33608712 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 33608712 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35484039 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 33846198 — Predictive Biomarker (PRD): Microsatellite instability
Study 33889958 — Predictive Biomarker (PRD): Leucine-rich alpha-2-glycoprotein
Genes: LRG1; LRG
Study 35271811 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34274079 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34274079 — Surrogate Endpoint (SUR): Blood pressure
Study 34850776 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study 34373299 — Surrogate Endpoint (SUR): Blood pressure
Study 34373299 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34785366 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34785366 — Safety Biomarker (SAF): BDNF
Study 33314699 — Surrogate Endpoint (SUR): Bone mineral density
Study 35247147 — Surrogate Endpoint (SUR): Blood pressure
Study 35139802 — Predictive Biomarker (PRD): GNL3 mRNA
Genes: GNL3; E2IG3; NS
Study 33625584 — Surrogate Endpoint (SUR): Blood pressure
Study 36278483 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 36278483 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 36278483 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 33632742 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 35044844 — Surrogate Endpoint (SUR): Blood pressure
Study 32894278 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33466462 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33157425 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 35697438 — Monitoring Biomarker (MOI): Procalcitonin
Study 33992852 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 33567859 — Safety Biomarker (SAF): Hyaluronic acid
Study 34587974 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35387919 — Predictive Biomarker (PRD): AQP3 mRNA
Genes: AQP3
Study 35387919 — Predictive Biomarker (PRD): HAS3 mRNA
Genes: HAS3
Study 32779711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32779711 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 32779711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32779711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33186683 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 33186683 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33186683 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 32428059 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32428059 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 34372971 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32852294 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33857782 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34360460 — Surrogate Endpoint (SUR): Blood pressure
Study 32915975 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 34684639 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 36034448 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 33211829 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33211829 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33211829 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 616542428 — Predictive Biomarker (PRD): GK mRNA
Genes: GK
Study 616542428 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34293933 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34293933 — Surrogate Endpoint (SUR): Blood pressure
Study 34481388 — Safety Biomarker (SAF): Reactive oxygen species
Study 34888397 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 34888397 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34888397 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 35192502 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 36007597 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36007597 — Surrogate Endpoint (SUR): Urinary oxalate
Study 33676294 — Predictive Biomarker (PRD): NTRK
Study 33676294 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 33035459 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study 32249609 — Surrogate Endpoint (SUR): Blood pressure
Study 33845867 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 33845867 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 33845867 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 32682556 — Surrogate Endpoint (SUR): Blood pressure
Study 33046136 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 32933625 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32933625 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32933625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33463583 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 32510158 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 32236818 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36079744 — Surrogate Endpoint (SUR): Bone mineral density
Study 32566096 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 32566096 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 32566096 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 32566096 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34923180 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 34923180 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 35637842 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 35908558 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35908558 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35908558 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33000490 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33000490 — Surrogate Endpoint (SUR): Pathological complete response
Study 32241670 — Predictive Biomarker (PRD): CHUK mRNA
Genes: CHUK; IKKA; TCF16
Study 35959685 — Surrogate Endpoint (SUR): Blood pressure
Study 34120835 — Safety Biomarker (SAF): Bacteroidetes phylum
Study 34172301 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 34172301 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 36265504 — Surrogate Endpoint (SUR): Serum testosterone
Study 34425788 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 34559118 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 34559118 — Monitoring Biomarker (MOI): HBV DNA
Study 35194433 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35194433 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 36171519 — Surrogate Endpoint (SUR): Blood pressure
Study 33507958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33507958 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33507958 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33099032 — Predictive Biomarker (PRD): PTH1R mRNA
Genes: PTH1R; PTHR; PTHR1
Study 32481487 — Surrogate Endpoint (SUR): Blood pressure
Study 33852121 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34512358 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35422766 — Surrogate Endpoint (SUR): Bone mineral density
Study 35456295 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 35274710 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 35274710 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 35316705 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 33647734 — Surrogate Endpoint (SUR): Blood pressure
Study 35152879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35152879 — Monitoring Biomarker (MOI): Procalcitonin
Study 35152879 — Surrogate Endpoint (SUR): Serum creatinine
Study 35152879 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 36038368 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 32054897 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 33383570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34374425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34374425 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34374425 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 36257081 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36257081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35120127 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36217012 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 35685584 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35685584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33350447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33350447 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 33350447 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 35959221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35959221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35959221 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32306606 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 33300382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34448354 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33790039 — Surrogate Endpoint (SUR): Blood pressure
Study 33051044 — Predictive Biomarker (PRD): CIDEA mRNA
Genes: CIDEA
Study 33051044 — Predictive Biomarker (PRD): PRDM16 mRNA
Genes: PRDM16; KIAA1675; MEL1; PFM13
Study 33051044 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study 33051044 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 33051044 — Predictive Biomarker (PRD): CPT1A mRNA
Genes: CPT1A; CPT1
Study 33051044 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 33051044 — Predictive Biomarker (PRD): ACO1 mRNA
Genes: ACO1; IREB1
Study 35986197 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 33428219 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32810293 — Surrogate Endpoint (SUR): Blood pressure
Study 35032862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35538396 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 33555941 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 33527721 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33527721 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein