TrialPanorama/TrialPanorama-database huggingface dataset:
Study 34262052 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34262052 — Predictive Biomarker (PRD): CXCR5 mRNA
Genes: CXCR5; BLR1; MDR15
Study 34262052 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 34262052 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study 34616361 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33499438 — Safety Biomarker (SAF): Hyaluronic acid
Study 33287626 — Surrogate Endpoint (SUR): Blood pressure
Study 33287626 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34907082 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 34907082 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 34907082 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 33222455 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35115339 — Surrogate Endpoint (SUR): Serum potassium
Study 35293153 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35440935 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 33423550 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 33423550 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 33423550 — Predictive Biomarker (PRD): ACVR1 mRNA
Genes: ACVR1; ACVRLK2
Study 32692755 — Predictive Biomarker (PRD): HCN4 mRNA
Genes: HCN4
Study 36254140 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 33445213 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study 33445213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36881396 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36881396 — Surrogate Endpoint (SUR): Blood pressure
Study 33125362 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 33125362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32139353 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 32139353 — Predictive Biomarker (PRD): TSTD1 mRNA
Genes: TSTD1; KAT
Study 34630103 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34090773 — Surrogate Endpoint (SUR): Blood pressure
Study 35394413 — Surrogate Endpoint (SUR): Blood pressure
Study 33588087 — Predictive Biomarker (PRD): CLK2 mRNA
Genes: CLK2
Study 33588087 — Predictive Biomarker (PRD): DYRK1A mRNA
Genes: DYRK1A; DYRK; MNB; MNBH
Study 33045417 — Safety Biomarker (SAF): Hyaluronic acid
Study 33423376 — Predictive Biomarker (PRD): SH3PXD2A mRNA
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study 33423376 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 32992998 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study 32992998 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 32992998 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 32992998 — Predictive Biomarker (PRD): MMP15 mRNA
Genes: MMP15
Study 32992998 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 35804049 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 36906404 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 33628758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33628758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33752741 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33721982 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 33827126 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33827126 — Surrogate Endpoint (SUR): Blood pressure
Study 34855657 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 36262727 — Surrogate Endpoint (SUR): Blood pressure
Study 36250951 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 34004154 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35246395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33262048 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33262048 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32191586 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35105495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35105495 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 35105495 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 34239050 — Surrogate Endpoint (SUR): Blood pressure
Study 32282308 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 32062741 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 32062741 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 35236649 — Surrogate Endpoint (SUR): Blood pressure
Study 34077510 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33098800 — Surrogate Endpoint (SUR): Blood pressure
Study 34638151 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33646147 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 33646147 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 32228379 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 32738875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 35503346 — Surrogate Endpoint (SUR): Blood pressure
Study 33185618 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 35184887 — Predictive Biomarker (PRD): BCAM mRNA
Genes: BCAM; LU; MSK19
Study 35184887 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 33690238 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 32039990 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 32039990 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 32331433 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32331433 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 32331433 — Predictive Biomarker (PRD): CELF2 mRNA
Genes: CELF2; BRUNOL3; CUGBP2; ETR3; NAPOR
Study 35689257 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 35689257 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 35689257 — Safety Biomarker (SAF): BDNF
Study 33009192 — Surrogate Endpoint (SUR): Blood pressure
Study 36096886 — Surrogate Endpoint (SUR): Bone mineral density
Study 34541650 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 34541650 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 34406128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34406128 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 34406128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33839787 — Surrogate Endpoint (SUR): Blood pressure
Study 32138661 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 32138661 — Predictive Biomarker (PRD): ACSL6 mRNA
Genes: ACSL6; ACS2; FACL6; KIAA0837; LACS5
Study 34501915 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 32238920 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 35190292 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 34029650 — Surrogate Endpoint (SUR): Bacterial count
Study 35157053 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32449418 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 35872584 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33558721 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 33558721 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 33006191 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33006191 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 33006191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34915907 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 34915907 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 34915907 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 36407843 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 36015163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36015163 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 36078296 — Surrogate Endpoint (SUR): Blood pressure
Study 34349181 — Surrogate Endpoint (SUR): Blood pressure
Study 35841202 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34127107 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 33152542 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 33667460 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32197933 — Safety Biomarker (SAF): Hyaluronic acid
Study 34403911 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33460575 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 34791296 — Surrogate Endpoint (SUR): Bone mineral density
Study 34238363 — Surrogate Endpoint (SUR): Blood pressure
Study 33305660 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 35165925 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 36075595 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 33609476 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 36026789 — Surrogate Endpoint (SUR): Blood pressure
Study 33044768 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33044768 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34486319 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32505383 — Surrogate Endpoint (SUR): Bone mineral density
Study 32188793 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33876875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33876875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33876875 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33876875 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33632285 — Predictive Biomarker (PRD): PMM2 mRNA
Genes: PMM2
Study 34103898 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 33050945 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 33050945 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35956324 — Surrogate Endpoint (SUR): Blood pressure
Study 35989964 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35122668 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 35122668 — Surrogate Endpoint (SUR): Bone mineral density
Study 34347945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33377987 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 34763504 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34763504 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 34763504 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35544384 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 34144047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32365000 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32365000 — Safety Biomarker (SAF): BDNF
Study 34160906 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 33462393 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 33462393 — Surrogate Endpoint (SUR): Blood pressure
Study 34739584 — Surrogate Endpoint (SUR): Blood pressure
Study 35778539 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34022462 — Surrogate Endpoint (SUR): Bone mineral density
Study 34658006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34981483 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 32951013 — Surrogate Endpoint (SUR): Blood pressure
Study 32951013 — Surrogate Endpoint (SUR): Serum sodium
Study 33308683 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 32654517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32654517 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32757651 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study 32757651 — Predictive Biomarker (PRD): GATA2 mRNA
Genes: GATA2
Study 32891160 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32891160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32891160 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32891160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32891160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32592986 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32592986 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32592986 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32907638 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34507355 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 34507355 — Predictive Biomarker (PRD): CALR mRNA
Genes: CALR; CRTC
Study 34507355 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 34507355 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 34507355 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 36251300 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 32251146 — Surrogate Endpoint (SUR): Bone mineral density
Study 33185928 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34503597 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 33073447 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 35439582 — Surrogate Endpoint (SUR): Blood pressure
Study 32546262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32546262 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35322978 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 35463906 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 35463906 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32729586 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 34551225 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36007987 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 36007987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36007987 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33026154 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 32229722 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33834628 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 33834628 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 33565308 — Surrogate Endpoint (SUR): Blood pressure
Study 33303692 — Surrogate Endpoint (SUR): Blood pressure
Study 33586783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33586783 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 33440342 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 35935235 — Predictive Biomarker (PRD): Calgranulin B
Genes: S100A9; CAGB; CFAG; MRP14
Study 35935235 — Predictive Biomarker (PRD): C4BPA mRNA
Genes: C4BPA; C4BP
Study 32789962 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32789962 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34515824 — Surrogate Endpoint (SUR): Blood pressure
Study 35045351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33562341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32308189 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32868544 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 32868544 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32868544 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 35647824 — Safety Biomarker (SAF): Hyaluronic acid
Study 36192751 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 36192751 — Surrogate Endpoint (SUR): Blood pressure
Study 36192751 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36192751 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32277749 — Surrogate Endpoint (SUR): Blood pressure
Study 35654820 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 35654820 — Safety Biomarker (SAF): Nucleotide triphosphate diphosphatase NUDT15
Genes: NUDT15; MTH2
Study 35654820 — Safety Biomarker (SAF): NUDT15
Genes: MTH2; FLJ10956
Study 32965249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33667726 — Predictive Biomarker (PRD): KHK mRNA
Genes: KHK
Study 32336045 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 36016763 — Surrogate Endpoint (SUR): Blood pressure
Study 35550457 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 35037816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34006540 — Predictive Biomarker (PRD): UBXN11 mRNA
Genes: UBXN11; SOC; UBXD5; PP2243
Study 34006540 — Surrogate Endpoint (SUR): Blood pressure
Study 35209951 — Surrogate Endpoint (SUR): Blood pressure
Study 33844258 — Surrogate Endpoint (SUR): Blood pressure
Study 32139505 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 32909439 — Safety Biomarker (SAF): Hyaluronic acid
Study 35060543 — Predictive Biomarker (PRD): ELOVL6 mRNA
Genes: ELOVL6; FACE; LCE
Study 35060543 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34970882 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 615007039 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32783220 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 33339480 — Surrogate Endpoint (SUR): Serum calcium
Study 35488356 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32383548 — Predictive Biomarker (PRD): SH2D1A mRNA
Genes: SH2D1A; DSHP; SAP
Study 34371972 — Surrogate Endpoint (SUR): Blood pressure
Study 32070136 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 32070136 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 33083468 — Predictive Biomarker (PRD): AQP1 mRNA
Genes: AQP1; CHIP28
Study 32886200 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32886200 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32886200 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32861500 — Surrogate Endpoint (SUR): Blood pressure
Study 35755939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34540184 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35312525 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 35312525 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 35074611 — Surrogate Endpoint (SUR): Blood pressure
Study 35936366 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35936366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35936366 — Surrogate Endpoint (SUR): Blood pressure
Study 35936366 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein