TrialPanorama/TrialPanorama-database huggingface dataset:
Study 36275715 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 36275715 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 36275941 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 36276500 — Predictive Biomarker (PRD): SIX1 mRNA
Genes: SIX1
Study 36276500 — Safety Biomarker (SAF): miR-9
Study 36276500 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-125b
Study 36276500 — Monitoring Biomarker (MOI): miR-26b-5p
Genes: MIR26B
Study 36277757 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 36278416 — Surrogate Endpoint (SUR): Blood pressure
Study 36279023 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 36279023 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 36279178 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 36279618 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 36279618 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36279715 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 36279879 — Predictive Biomarker (PRD): POMP mRNA
Genes: POMP; C13orf12; UMP1; HSPC014; HSPC036; PNAS-110
Study 36280861 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 36280861 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36281165 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 36281310 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36281310 — Surrogate Endpoint (SUR): Blood pressure
Study 36281983 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36282800 — Monitoring Biomarker (MOI): Procalcitonin
Study 36282800 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36283759 — Predictive Biomarker (PRD): PLA2R1 mRNA
Genes: PLA2R1; CLEC13C
Study 36284220 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 36286755 — Surrogate Endpoint (SUR): Serum creatinine
Study 36286865 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 36287231 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36287248 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 36287602 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 36287602 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 36288238 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 36288238 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 36288238 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36288238 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 36288281 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 36288281 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 36288512 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study 36288547 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36288619 — Predictive Biomarker (PRD): LAMP2 mRNA
Genes: LAMP2
Study 36288714 — Pharmacodynamic Biomarker (PDY): Ataxin-2
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 36289094 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 36289094 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 36291172 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 36291172 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 36291397 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 36291912 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 36293719 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36297443 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 36298700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 36298700 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 36299500 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 36300662 — Surrogate Endpoint (SUR): Blood pressure
Study 36301137 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 36301137 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 36301599 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 36301921 — Predictive Biomarker (PRD): PPP6R2 mRNA
Genes: PPP6R2; KIAA0685; PP6R2; SAPS2
Study 36302175 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36302175 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 36302562 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36302586 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36303108 — Surrogate Endpoint (SUR): Serum sodium
Study 36303228 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 36303228 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 36303228 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36303228 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36303432 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36303432 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 36306532 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36306810 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36306810 — Surrogate Endpoint (SUR): Pathological complete response
Study 36307410 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 36307410 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 36307738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36307738 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36307738 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 36307775 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36307775 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 36307775 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 36307775 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 36307803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36307803 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36307826 — Predictive Biomarker (PRD): NDRG1 mRNA
Genes: NDRG1; CAP43; DRG1; RTP
Study 36309488 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 36309748 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 36309837 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 36311227 — Surrogate Endpoint (SUR): Blood pressure
Study 36313145 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 36314106 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 36314160 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 36314507 — Surrogate Endpoint (SUR): Bone mineral density
Study 36314999 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36315007 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 36315566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36315566 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 36316335 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36316335 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 36316704 — Predictive Biomarker (PRD): HDGFL2 mRNA
Genes: HDGFL2; HDGF2; HDGFRP2; HRP2; UNQ785/PRO1604
Study 36317715 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 36317959 — Monitoring Biomarker (MOI): HBV DNA
Study 36318307 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 36318705 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 36318705 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 36318705 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 36318879 — Surrogate Endpoint (SUR): Blood pressure
Study 36322537 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36322608 — Surrogate Endpoint (SUR): Blood pressure
Study 36322627 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 36322714 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 36322825 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 36323235 — Predictive Biomarker (PRD): MGAT2 mRNA
Genes: MGAT2
Study 36323235 — Predictive Biomarker (PRD): DGAT1 mRNA
Genes: DGAT1; AGRP1; DGAT
Study 36323235 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 36323479 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 36323612 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36324098 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 36325355 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-125b
Study 36325389 — Predictive Biomarker (PRD): DHODH mRNA
Genes: DHODH
Study 36325389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36326797 — Surrogate Endpoint (SUR): Blood pressure
Study 36327094 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 36327094 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 36327094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36327624 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36328033 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36328377 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36328378 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 36328378 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 36328399 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36328690 — Surrogate Endpoint (SUR): Blood pressure
Study 36328903 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36329083 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 36329366 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 36329512 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 36330484 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 36330490 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 36330490 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36330525 — Safety Biomarker (SAF): Arginase-1
Genes: ARG1
Study 36331676 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 36331676 — Safety Biomarker (SAF): Hyaluronic acid
Study 36332004 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 36332004 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study 36332004 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 36332294 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 36332763 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36332763 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 36332964 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 36332964 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36333289 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 36333682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36333718 — Predictive Biomarker (PRD): UBXN11 mRNA
Genes: UBXN11; SOC; UBXD5; PP2243
Study 36334048 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 36335120 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36335120 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36335120 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 36335120 — Predictive Biomarker (PRD): Hormone receptor
Study 36335217 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 36335479 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36337904 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 36338165 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 36338362 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 36338415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36338481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36338481 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 36338481 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 36338546 — Predictive Biomarker (PRD): WEE1 mRNA
Genes: WEE1
Study 36338546 — Predictive Biomarker (PRD): CDC7 mRNA
Genes: CDC7; CDC7L1
Study 36338546 — Pharmacodynamic Biomarker (PDY): Cyclin-dependent kinase 1
Genes: CDK1; CDC2; CDC28A; CDKN1; P34CDC2
Study 36339117 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36339926 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 36342104 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 36342120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36342269 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 36342342 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36342342 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36342343 — Safety Biomarker (SAF): BDNF
Study 36342421 — Predictive Biomarker (PRD): SCAI mRNA
Genes: SCAI; C9orf126
Study 36342455 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 36342455 — Predictive Biomarker (PRD): IRF7 mRNA
Genes: IRF7
Study 36342455 — Predictive Biomarker (PRD): IFNAR1 mRNA
Genes: IFNAR1; IFNAR
Study 36342619 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36342972 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 36344663 — Surrogate Endpoint (SUR): Blood pressure
Study 36344770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36345253 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 36345941 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36345941 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 36346005 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36346366 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 36346366 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 36346366 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 36346366 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study 36346366 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 36346366 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 36346366 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 36346366 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 36347049 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36349793 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36350017 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 36350312 — Predictive Biomarker (PRD): DNER mRNA
Genes: DNER; BET; UNQ262/PRO299
Study 36350899 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 36351402 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 36351919 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 36351931 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 36352028 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36352028 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36352028 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 36352423 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 36353571 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 36355054 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study 36355613 — Surrogate Endpoint (SUR): Blood pressure
Study 36357087 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 36357087 — Predictive Biomarker (PRD): OSBP mRNA
Genes: OSBP; OSBP1
Study 36357087 — Surrogate Endpoint (SUR): Blood pressure
Study 36357295 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 36357392 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 36357934 — Predictive Biomarker (PRD): Hormone receptor
Study 36358694 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36358930 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 36360424 — Surrogate Endpoint (SUR): Serum calcium
Study 36367058 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 36367600 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 36367600 — Predictive Biomarker (PRD): MMP7 mRNA
Genes: MMP7; MPSL1; PUMP1
Study 36367600 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 36367600 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 36367600 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 36367600 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Sclerostin
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study 36367600 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 36367769 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 36367894 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 36368939 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36369028 — Predictive Biomarker (PRD): TAAR1 mRNA
Genes: TAAR1; TA1; TAR1; TRAR1
Study 36369156 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36369278 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 36369278 — Predictive Biomarker (PRD): SHD mRNA
Genes: SHD
Study 36369278 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 36369507 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 36369848 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 36370742 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 36371196 — Predictive Biomarker (PRD): ZNF789 mRNA
Genes: ZNF789
Study 36371196 — Predictive Biomarker (PRD): H1-0 mRNA
Genes: H1-0; H1F0; H1FV
Study 36371196 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 36371222 — Surrogate Endpoint (SUR): Serum hemoglobin A1C
Study 36371226 — Predictive Biomarker (PRD): CD276 mRNA
Genes: CD276; B7H3; PSEC0249; UNQ309/PRO352
Study 36371408 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 36371408 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 36371986 — Predictive Biomarker (PRD): PNPLA2 mRNA
Genes: PNPLA2; ATGL; FP17548
Study 36371986 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 36372245 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 36372251 — Predictive Biomarker (PRD): DOCK3 mRNA
Genes: DOCK3; KIAA0299; MOCA
Study 36372356 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 36372873 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 36372884 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 36373234 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 36374541 — Surrogate Endpoint (SUR): Blood pressure
Study 36375046 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 36375120 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 36375125 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 36375981 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36375985 — Surrogate Endpoint (SUR): Blood pressure
Study 36376393 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36376560 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 36376833 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 36376833 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 36376833 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36377504 — Safety Biomarker (SAF): miR-652
Genes: MIR652
Study 36377523 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 36377523 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36378074 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 36378539 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36378673 — Predictive Biomarker (PRD): SCAI mRNA
Genes: SCAI; C9orf126
Study 36379002 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36379575 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1