TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35328990 — Safety Biomarker (SAF): Hyaluronic acid
Study 32100647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 34807983 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 32792079 — Surrogate Endpoint (SUR): Blood pressure
Study 32392574 — Surrogate Endpoint (SUR): Total kidney volume
Study 33915788 — Predictive Biomarker (PRD): IGFBP2 mRNA
Genes: IGFBP2; BP2; IBP2
Study 32092472 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 32092472 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 35383114 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 33293804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33763127 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 32071118 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32071118 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 32071118 — Predictive Biomarker (PRD): Hormone receptor
Study 616389246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 616389246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35378068 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 35378068 — Surrogate Endpoint (SUR): Blood pressure
Study 32758455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34454572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34454572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34454572 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34454572 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32229444 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 35334197 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35482101 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 33534859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33637882 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study 33902584 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32112591 — Predictive Biomarker (PRD): Hormone receptor
Study 35902633 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33596848 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 32019783 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35832418 — Surrogate Endpoint (SUR): Bone mineral density
Study 34621054 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32965230 — Surrogate Endpoint (SUR): Blood pressure
Study 35267206 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 36031810 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 36031810 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34412057 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 34088513 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33318391 — Surrogate Endpoint (SUR): Blood pressure
Study 33231866 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 34789450 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 33199422 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 33200899 — Predictive Biomarker (PRD): MISP mRNA
Genes: MISP; C19orf21
Study 32599641 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 35918278 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35230585 — Predictive Biomarker (PRD): Hormone receptor
Study 33610421 — Surrogate Endpoint (SUR): Blood pressure
Study 33930939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33076952 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 35244061 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 33822033 — Surrogate Endpoint (SUR): Blood pressure
Study 33046619 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36159012 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 36159012 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 33190147 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33190147 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33190147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35510753 — Predictive Biomarker (PRD): CD79A mRNA
Genes: CD79A; IGA; MB1
Study 36369798 — Predictive Biomarker (PRD): TYK2 mRNA
Genes: TYK2
Study 34209804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34355814 — Surrogate Endpoint (SUR): Bone mineral density
Study 32339320 — Surrogate Endpoint (SUR): Serum testosterone
Study 34632490 — Surrogate Endpoint (SUR): Serum creatinine
Study 34632490 — Surrogate Endpoint (SUR): Blood pressure
Study 32645158 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34211015 — Surrogate Endpoint (SUR): Blood pressure
Study 36195924 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 33952670 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 33227454 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 36482733 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 33860324 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 33609457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33609457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33609457 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 34132690 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34132690 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33533320 — Surrogate Endpoint (SUR): Blood pressure
Study 34890214 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34890214 — Predictive Biomarker (PRD): Hormone receptor
Study 33313768 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 36074963 — Surrogate Endpoint (SUR): Blood pressure
Study 32403367 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 32403367 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 32697484 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35038337 — Predictive Biomarker (PRD): LIPE mRNA
Genes: LIPE
Study 35038337 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 35038337 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 35038337 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 35038337 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 35038337 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 35038337 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 36334223 — Surrogate Endpoint (SUR): Blood pressure
Study 34405412 — Predictive Biomarker (PRD): ARAF mRNA
Genes: ARAF; ARAF1; PKS; PKS2
Study 34405412 — Predictive Biomarker (PRD): BLOC1S4 mRNA
Genes: BLOC1S4; CNO
Study 33310418 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study 34424995 — Surrogate Endpoint (SUR): Serum creatinine
Study 33153578 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34903035 — Surrogate Endpoint (SUR): Blood pressure
Study 35999562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34712203 — Surrogate Endpoint (SUR): Serum uric acid
Study 33606922 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 35920102 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 35920102 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 34187829 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 34735441 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32224279 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 32224279 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 32560639 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32560639 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34807763 — Predictive Biomarker (PRD): SRY mRNA
Genes: SRY; TDF
Study 34807763 — Monitoring Biomarker (MOI): HBV DNA
Study 32654362 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32924897 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 33636417 — Surrogate Endpoint (SUR): Blood pressure
Study 32587298 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 34116204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34403293 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 32419281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32936442 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33976537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33976537 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36476361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36476361 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 36476361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33395437 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 32829585 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 32829585 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32127335 — Surrogate Endpoint (SUR): Blood pressure
Study 32127335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32127335 — Surrogate Endpoint (SUR): Serum triglycerides
Study 34131051 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33472925 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 33807731 — Surrogate Endpoint (SUR): Blood pressure
Study 32464903 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 34148021 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34713983 — Surrogate Endpoint (SUR): Serum testosterone
Study 34210788 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33284338 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 33284338 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 33184146 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33184146 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33873106 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33044283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33044283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33044283 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32179428 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32179428 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 35754107 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 34342185 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 32755218 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 34405547 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34405547 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 36079817 — Surrogate Endpoint (SUR): Blood pressure
Study 33254235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36243929 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36243929 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 36243929 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 36243929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36243929 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 32791030 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HSD3B1 mRNA
Genes: HSD3B1; 3BH; HSDB3A
Study 33331448 — Surrogate Endpoint (SUR): Blood pressure
Study 36085409 — Surrogate Endpoint (SUR): Probing pocket depth
Study 35121932 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 35121932 — Predictive Biomarker (PRD): LY75 mRNA
Genes: LY75; CD205; CLEC13B
Study 34032900 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 35723596 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35723596 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 616626291 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35092084 — Predictive Biomarker (PRD): COL3A1 mRNA
Genes: COL3A1
Study 32394723 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32295624 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 35787963 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 35787963 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 33709626 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34294642 — Surrogate Endpoint (SUR): Serum calcium
Study 34294642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34583675 — Monitoring Biomarker (MOI): Procalcitonin
Study 34583675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32988624 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study 32988624 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 33243221 — Surrogate Endpoint (SUR): Blood pressure
Study 34776146 — Surrogate Endpoint (SUR): Blood pressure
Study 32408817 — Predictive Biomarker (PRD): RRS1 mRNA
Genes: RRS1; KIAA0112; RRR
Study 34293615 — Predictive Biomarker (PRD): CYP1A1 mRNA
Genes: CYP1A1
Study 34293615 — Predictive Biomarker (PRD): UGT2A1 mRNA
Genes: UGT2A1
Study 34293615 — Predictive Biomarker (PRD): HPGDS mRNA
Genes: HPGDS; GSTS; PGDS; PTGDS2
Study 34293615 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 34293615 — Predictive Biomarker (PRD): ACOX2 mRNA
Genes: ACOX2
Study 34293615 — Safety Biomarker (SAF): Fatty acid binding protein 1
Genes: FABP1; FABPL
Study 34293615 — Predictive Biomarker (PRD): PAICS mRNA
Genes: PAICS; ADE2; AIRC; PAIS
Study 35704951 — Predictive Biomarker (PRD): PDE10A mRNA
Genes: PDE10A
Study 35793881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35793881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34552099 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 35419986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32734457 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 34663438 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 33060436 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33060436 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 33060436 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36383175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34176847 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32064725 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 32064725 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 34933717 — Predictive Biomarker (PRD): PEMT mRNA
Genes: PEMT; PEMPT; PNMT
Study 35605426 — Surrogate Endpoint (SUR): Blood pressure
Study 32925039 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32925039 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32925039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32925039 — Safety Biomarker (SAF): BDNF
Study 32925039 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32925039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33474705 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 34224554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34674667 — Surrogate Endpoint (SUR): Serum potassium
Study 34674667 — Surrogate Endpoint (SUR): Blood pressure
Study 36493792 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36493792 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36493792 — Predictive Biomarker (PRD): Hormone receptor
Study 36493792 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 32930952 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 32930952 — Predictive Biomarker (PRD): CYP1A1 mRNA
Genes: CYP1A1
Study 32930952 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 33012244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33012244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35373862 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 35373862 — Surrogate Endpoint (SUR): Blood pressure
Study 32880050 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32880050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36444740 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 35728900 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35728900 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36213929 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36213929 — Surrogate Endpoint (SUR): Blood pressure
Study 34547471 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 34275593 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34172012 — Safety Biomarker (SAF): Reactive oxygen species
Study 35726893 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 35446902 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 35446902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 33273290 — Surrogate Endpoint (SUR): Bone mineral density
Study 32586771 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 32569068 — Surrogate Endpoint (SUR): Serum creatinine
Study 34420949 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 35897060 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35897060 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34481963 — Surrogate Endpoint (SUR): Blood pressure
Study 32978696 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32978696 — Predictive Biomarker (PRD): ACHE mRNA
Genes: ACHE
Study 32978696 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33236464 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32213023 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 34181580 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 34181580 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 32353001 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 34325831 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 34325831 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32518064 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP