TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05042583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05139004 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT06383338 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT06383338 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT06383338 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT06574958 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT05144139 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05144139 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06215846 — Safety Biomarker (SAF): Interleukin 12
Study NCT06580132 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06634745 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06333678 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05543161 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT05543161 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04951492 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT06415656 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06309979 — Surrogate Endpoint (SUR): Annualized growth velocity
Study NCT05010564 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05010564 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT06687564 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ACTG2 mRNA
Genes: ACTG2; ACTA3; ACTL3; ACTSG
Study NCT05795595 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT06580574 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06580574 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06580574 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT05672147 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT06712628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06305754 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06305754 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06706310 — Monitoring Biomarker (MOI): HBV DNA
Study NCT06724614 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT06747572 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study NCT06747858 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT06761716 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study NCT06769828 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT05657301 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05489783 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT04882475 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04882475 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05759273 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT06769191 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT06766903 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06770426 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06773585 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT06775743 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06775743 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06775743 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06775743 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06776302 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05118789 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT05404321 — Predictive Biomarker (PRD): LGR5 mRNA
Genes: LGR5; GPR49; GPR67
Study NCT05404321 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06444152 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05271916 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05271916 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05693142 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06484517 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06349369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05003492 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT05003492 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05038644 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT04765514 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT05985330 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT06264011 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06503211 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05820399 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05220306 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04939441 — Monitoring Biomarker (MOI): HBV DNA
Study NCT05864144 — Predictive Biomarker (PRD): VSIR mRNA
Genes: VSIR; C10orf54; SISP1; VISTA; PP2135; UNQ730/PRO1412
Study NCT05898126 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT06363734 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06363734 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06186297 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00002320 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06034691 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT06122922 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00002043 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04669496 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05366634 — Predictive Biomarker (PRD): MDK mRNA
Genes: MDK; MK1; NEGF2
Study NCT04982900 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05153902 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04690595 — Predictive Biomarker (PRD): TNFRSF13C mRNA
Genes: TNFRSF13C; BAFFR; BR3
Study NCT06669026 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT05779124 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study NCT05942573 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05183165 — Predictive Biomarker (PRD): ATP7B mRNA
Genes: ATP7B; PWD; WC1; WND
Study NCT04689945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05114343 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05967325 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT06548555 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04745975 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05162495 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05645601 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05568953 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05563272 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT06265363 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05247996 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT05221658 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05841875 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT05841875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05075824 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05233033 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study NCT05197192 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT06253520 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06726382 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04912427 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT05524051 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05814965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05814965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05474430 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT05474430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05474430 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study NCT04729075 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04729075 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT05127876 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05219487 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT06411457 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06719674 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT06745882 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06745882 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06745882 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT05951452 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT05951452 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT06754098 — Predictive Biomarker (PRD): TK2 mRNA
Genes: TK2
Study NCT06754098 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT04505007 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04658004 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study NCT06777199 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05922345 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06120764 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05611931 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT06740578 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT06757881 — Predictive Biomarker (PRD): IL1RAP mRNA
Genes: IL1RAP; C3orf13; IL1R3
Study NCT05628883 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT05628883 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00002092 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06118372 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT06635369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06043323 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05757310 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06756334 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06757712 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT06756633 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06756633 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06758024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06758024 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT05439889 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT05439889 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT05579353 — Predictive Biomarker (PRD): LRBA mRNA
Genes: LRBA; BGL; CDC4L; LBA
Study NCT06204549 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06260722 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06530823 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT05389761 — Predictive Biomarker (PRD): AOC1 mRNA
Genes: AOC1; ABP1; DAO1
Study NCT05880303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05991752 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT05991752 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study NCT05838768 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT05205291 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT05849298 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05477901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04880304 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT05890183 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05584930 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study NCT05584930 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study NCT05400577 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06066411 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05423496 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05234047 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06186154 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT06186154 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT05781074 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study NCT06055504 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06301321 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT06301321 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT05523336 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study NCT05523336 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT04713488 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04713488 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06000748 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05594797 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05577208 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06079398 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study NCT05597033 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06108219 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00681148 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT05091424 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT05091424 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT06222827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06328036 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study NCT06328036 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06208904 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT06219096 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04866173 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05681325 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT05432193 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT06369974 — Predictive Biomarker (PRD): TUBB4A mRNA
Genes: TUBB4A; TUBB4; TUBB5
Study NCT06649253 — Predictive Biomarker (PRD): CD9 mRNA
Genes: CD9; MIC3; TSPAN29; GIG2
Study NCT06180785 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study NCT05467748 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study NCT06474923 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT06047574 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06047574 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT05293405 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT06507280 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT04832022 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05598190 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05598190 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04583917 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04583917 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study NCT05698342 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06756308 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT06752824 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06752785 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06752785 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT06513338 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT05878184 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00000831 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05797753 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT06285682 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study NCT06222580 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05953168 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05953168 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05244473 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05025592 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT05025592 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05512351 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05222191 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05222191 — Surrogate Endpoint (SUR): Serum potassium
Study NCT06124963 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study NCT05756270 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05359887 — Safety Biomarker (SAF): DRD2
Study NCT06609655 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05077579 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06359717 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06431282 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05861336 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT06015204 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT05367570 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06635681 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT06635681 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT06635681 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05801029 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06726564 — Predictive Biomarker (PRD): CD276 mRNA
Genes: CD276; B7H3; PSEC0249; UNQ309/PRO352
Study NCT06726057 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06726109 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT06573450 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT06573450 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT06573450 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT06727084 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT06151028 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06254313 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT05398029 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT06468280 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT06468280 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT06242808 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04876248 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05455060 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05455060 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT05156788 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study NCT06362096 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05722418 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06083961 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT05007379 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05187624 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF