TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05400993 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05603065 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT06250738 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06047197 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04241536 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05193292 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04379258 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03921164 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06024746 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06416410 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06366230 — Surrogate Endpoint (SUR): Serum potassium
Study NCT06368934 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study NCT06127108 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04226898 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04961385 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06377735 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study NCT06153407 — Predictive Biomarker (PRD): STUB1 mRNA
Genes: STUB1; CHIP; PP1131
Study NCT06123039 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05580068 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05598424 — Predictive Biomarker (PRD): CST1 mRNA
Genes: CST1
Study NCT05082259 — Predictive Biomarker (PRD): XIAP mRNA
Genes: XIAP; API3; BIRC4; IAP3
Study NCT04826016 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05450523 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT05792761 — Monitoring Biomarker (MOI): HBV DNA
Study NCT06148402 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04999605 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05914233 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05124171 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04849338 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT05916755 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT05345691 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05345691 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06024174 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05756660 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT00001022 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05756933 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06502847 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT06262737 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05392205 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05632380 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05158829 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT05611853 — Predictive Biomarker (PRD): CD74 mRNA
Genes: CD74; DHLAG
Study NCT05064644 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT05693987 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05439538 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT05439538 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06187012 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06068816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04920747 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06362538 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05474885 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05474885 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05256511 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05987098 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study NCT06478134 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05029011 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05760196 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05041725 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT04864717 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05329064 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05222932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06226662 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study NCT05554783 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06028906 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06287086 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT06287086 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06371976 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT06330649 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05423262 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT04774367 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study NCT04774367 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study NCT04796350 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04280211 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02636686 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT05718869 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05718869 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05464368 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06395259 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT05761158 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study NCT05590143 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05590143 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06364046 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study NCT05822284 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05433597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04589065 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05800275 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06319651 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06199453 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06387784 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06302725 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06083610 — Safety Biomarker (SAF): miR-133a
Study NCT06584019 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04924153 — Predictive Biomarker (PRD): KCNT1 mRNA
Genes: KCNT1; KIAA1422
Study NCT06560905 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05887739 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study NCT06298448 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT05436210 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT05347511 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT05347511 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT06112236 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT05913869 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study NCT05256810 — Predictive Biomarker (PRD): XDH mRNA
Genes: XDH; XDHA
Study NCT05256810 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT06657274 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study NCT06657274 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06657274 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06663137 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT05818280 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05043974 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05024136 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06344156 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05299411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05299411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05011526 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05477823 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT05563831 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT05254379 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05611528 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study NCT05611528 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT05861141 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04893694 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04893694 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05286918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04719715 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study NCT05185037 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04628988 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT05553184 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05328024 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05918120 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05038488 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05905965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05919537 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study NCT05919537 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT05254327 — Predictive Biomarker (PRD): BMX mRNA
Genes: BMX
Study NCT06576492 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT05647564 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT06533670 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06331897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05143112 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04811326 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study NCT06158711 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT06522451 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT06217588 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study NCT06217588 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06338475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06439758 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05088109 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study NCT05238649 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04863118 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04863118 — Safety Biomarker (SAF): BDNF
Study NCT05412160 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study NCT05586841 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05586841 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05586841 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05825391 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study NCT05409898 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05331794 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05331794 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05095350 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04798716 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04798716 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05696223 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study NCT05721014 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06058338 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05270798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00000642 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05693792 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04897763 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT05656131 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06431620 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT04767984 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT04767984 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT06584162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05860465 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05860465 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05860465 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06269796 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study NCT06043362 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT06429800 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04908813 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06195189 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06195189 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05246813 — Predictive Biomarker (PRD): STUB1 mRNA
Genes: STUB1; CHIP; PP1131
Study NCT05376345 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04732871 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05643547 — Predictive Biomarker (PRD): IL7 mRNA
Genes: IL7
Study NCT05643547 — Pharmacodynamic Biomarker (PDY): Interleukin 7 receptor alpha
Genes: IL7R
Study NCT06572904 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05662072 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05797805 — Predictive Biomarker (PRD): TBL1X mRNA
Genes: TBL1X; TBL1
Study NCT06457698 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05502016 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05169411 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04937608 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT06198543 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06469528 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06024018 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT05341921 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06536179 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT05620160 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05892952 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06663748 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06316817 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04064697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05858645 — Predictive Biomarker (PRD): TYK2 mRNA
Genes: TYK2
Study NCT05779917 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT05779917 — Predictive Biomarker (PRD): GUCY2C mRNA
Genes: GUCY2C; GUC2C; STAR
Study NCT04929080 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study NCT04715022 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05621174 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05655013 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT05655013 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05492968 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05047848 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04692298 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05305742 — Surrogate Endpoint (SUR): Bacterial count
Study NCT05995899 — Safety Biomarker (SAF): Sodium/hydrogen exchanger 3
Genes: SLC9A3; NHE3
Study NCT06059469 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05331976 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05641805 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04742361 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06401837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05071222 — Predictive Biomarker (PRD): DCLRE1C mRNA
Genes: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C
Study NCT05071222 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02844530 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT06535178 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02503280 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05331183 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT05331183 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study NCT05710289 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05710289 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05460013 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT05460013 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04598516 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05837299 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT06205979 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06205979 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06205979 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04779957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05414578 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study NCT05414578 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study NCT04702425 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT04702425 — Predictive Biomarker (PRD): Induced myeloid leukemia cell differentiation protein Mcl-1
Genes: MCL1; BCL2L3
Study NCT05101564 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05101564 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05042284 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT05042284 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT04292080 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05245838 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study NCT04923945 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05009199 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT05009199 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study NCT05421767 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05603598 — Predictive Biomarker (PRD): LEAP2 mRNA
Genes: LEAP2
Study NCT04785924 — Predictive Biomarker (PRD): REL mRNA
Genes: REL
Study NCT05737381 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT05432921 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06050759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06131775 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT05290441 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05004363 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT05004363 — Surrogate Endpoint (SUR): Serum potassium
Study NCT05357924 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT05724654 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT05633160 — Predictive Biomarker (PRD): GRPR mRNA
Genes: GRPR
Study NCT05904964 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05904964 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05920863 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT05920863 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT06457802 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05696613 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT05750589 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05914662 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05691205 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT05218525 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06536309 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF