TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32819305 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33794865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33794865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33794865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35144591 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 35144591 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34632493 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33028387 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 34992091 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 32678677 — Safety Biomarker (SAF): Interleukin 1
Study 32678677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33647246 — Surrogate Endpoint (SUR): Blood pressure
Study 34418400 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 35459713 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36116392 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 35195530 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 32236999 — Safety Biomarker (SAF): BDNF
Study 34789441 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 34789441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33278671 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33278671 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 33247731 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33992285 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 32750305 — Safety Biomarker (SAF): BDNF
Study 32750305 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33847743 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32180481 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35166788 — Surrogate Endpoint (SUR): Blood pressure
Study 34110954 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 34670012 — Predictive Biomarker (PRD): SELENOP mRNA
Genes: SELENOP; SELP; SEPP1
Study 35834254 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32816351 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CTNNB1 mRNA
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study 32320482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36264343 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 33199443 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33199443 — Monitoring Biomarker (MOI): Cell-free DNA
Study 33440084 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33653824 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33653824 — Surrogate Endpoint (SUR): Blood pressure
Study 33091093 — Surrogate Endpoint (SUR): Blood pressure
Study 36028326 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 34088583 — Surrogate Endpoint (SUR): Blood pressure
Study 35360515 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 32019222 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 32019222 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34334434 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 33455099 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 33455099 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33455099 — Monitoring Biomarker (MOI): HBV DNA
Study 33564872 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34525006 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 34525006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35529264 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 33648489 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 32468916 — Predictive Biomarker (PRD): ABCC8 mRNA
Genes: ABCC8; HRINS; SUR; SUR1
Study 36353135 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 34503198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34503198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34503198 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 34503198 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 34503198 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 36451471 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 36451471 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36451471 — Safety Biomarker (SAF): Interleukin 1
Study 32291702 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 33093947 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 33093947 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 32498534 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 32443684 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 35979056 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 32866928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35413116 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 35413116 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33341226 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32692493 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 32692493 — Surrogate Endpoint (SUR): Blood pressure
Study 33839788 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 32209975 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 34791107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32592657 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 33711638 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 33863853 — Surrogate Endpoint (SUR): Blood pressure
Study 34546614 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33170863 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33725153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33808784 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 32867992 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32867992 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32756564 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 32756564 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 34843406 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 34749994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32634544 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 35057413 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 35057413 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 616973594 — Surrogate Endpoint (SUR): Serum testosterone
Study 32762882 — Monitoring Biomarker (MOI): HBV DNA
Study 35837991 — Surrogate Endpoint (SUR): Blood pressure
Study 35837991 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33109244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34728032 — Surrogate Endpoint (SUR): Serum sodium
Study 35947349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34747048 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 34822189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32416690 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 32416690 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32418809 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 32574844 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 32687266 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 32687266 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 36147622 — Predictive Biomarker (PRD): ASPSCR1 mRNA
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 33772557 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 34475328 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 32951729 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34906386 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 34906386 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 33829223 — Surrogate Endpoint (SUR): Bone mineral density
Study 33217833 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33217833 — Surrogate Endpoint (SUR): Blood pressure
Study 34529000 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34529000 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34529000 — Predictive Biomarker (PRD): Hormone receptor
Study 34251303 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 32759543 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33772508 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 32791671 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 34721377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35483753 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32046931 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36330556 — Predictive Biomarker (PRD): ACP3 mRNA
Genes: ACP3; ACPP
Study 34551104 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 35320359 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35997135 — Predictive Biomarker (PRD): ADAM8 mRNA
Genes: ADAM8; MS2
Study 32402554 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32402554 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35277669 — Surrogate Endpoint (SUR): Blood pressure
Study 33019896 — Surrogate Endpoint (SUR): Blood pressure
Study 34177933 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 34177933 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 35961250 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 32303765 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32303765 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36075592 — Surrogate Endpoint (SUR): Bone mineral density
Study 34479797 — Surrogate Endpoint (SUR): Bone mineral density
Study 35290742 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 35316689 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 32556730 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33499714 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 33512412 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 33954789 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 33954789 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 33954789 — Surrogate Endpoint (SUR): Bone mineral density
Study 34970330 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 35849397 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 36278221 — Surrogate Endpoint (SUR): Blood pressure
Study 34431518 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 34431518 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 33567701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33567701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36320143 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 33262767 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 33262767 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33262767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33598778 — Safety Biomarker (SAF): Hyaluronic acid
Study 34382725 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 35671100 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 36075589 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33284201 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 32502443 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33404812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33404812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32339499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32339499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33546069 — Surrogate Endpoint (SUR): Blood pressure
Study 32313941 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34170062 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32906032 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study 32906032 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35209934 — Surrogate Endpoint (SUR): Blood pressure
Study 33525480 — Surrogate Endpoint (SUR): Blood pressure
Study 35820629 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 35820629 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 34331551 — Predictive Biomarker (PRD): PLAA mRNA
Genes: PLAA; PLAP
Study 32166994 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 33360679 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35160276 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35160276 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 35160276 — Surrogate Endpoint (SUR): Blood pressure
Study 35229141 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32669957 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 33806310 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33806310 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 34418903 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32909274 — Predictive Biomarker (PRD): MEFV mRNA
Genes: MEFV; MEF; TRIM20
Study 32909274 — Predictive Biomarker (PRD): ADA2 mRNA
Genes: ADA2; ADGF; CECR1; IDGFL
Study 32909274 — Predictive Biomarker (PRD): MVK mRNA
Genes: MVK
Study 32909274 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 32909274 — Predictive Biomarker (PRD): NOD2 mRNA
Genes: NOD2; CARD15; IBD1
Study 32909274 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 33249881 — Surrogate Endpoint (SUR): Blood pressure
Study 33955231 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36210434 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32652799 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 34543722 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 32761890 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 34176293 — Surrogate Endpoint (SUR): Blood pressure
Study 32641226 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32641226 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33480227 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 33055007 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 33055007 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 32001336 — Predictive Biomarker (PRD): C6orf15 mRNA
Genes: C6orf15; STG; UNQ1840/PRO3566
Study 33771837 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 36082214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36082214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36082214 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 36163349 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 34311108 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34311108 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34661821 — Predictive Biomarker (PRD): Hormone receptor
Study 34661821 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 34844156 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34844156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32696575 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 35700588 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 34554208 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 32396017 — Surrogate Endpoint (SUR): Blood pressure
Study 32396017 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32396017 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36075200 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34265491 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 35056360 — Surrogate Endpoint (SUR): Blood pressure
Study 32645890 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32645890 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32645890 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 35126684 — Surrogate Endpoint (SUR): Serum uric acid
Study 33801688 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33801688 — Safety Biomarker (SAF): BDNF
Study 35912157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35634851 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 35795940 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35795940 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33177622 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 33839105 — Surrogate Endpoint (SUR): Blood pressure
Study 35692368 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33484027 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33385766 — Surrogate Endpoint (SUR): Blood pressure
Study 35676803 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 35676803 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34750334 — Surrogate Endpoint (SUR): Blood pressure
Study 33427772 — Safety Biomarker (SAF): Hyaluronic acid
Study 32009091 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32009091 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35584433 — Surrogate Endpoint (SUR): Blood pressure
Study 35584433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35386698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35386698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2