TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05384119 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05384119 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04866628 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05228470 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT06144957 — Predictive Biomarker (PRD): SLC13A5 mRNA
Genes: SLC13A5; NACT
Study NCT05200104 — Predictive Biomarker (PRD): AMN mRNA
Genes: AMN; UNQ513/PRO1028
Study NCT05200104 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study NCT06341166 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study NCT06261034 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04752293 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04752293 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04752293 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT04679233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05940610 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05442749 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05007652 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05987566 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05799287 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05131204 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT05131204 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT05380284 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05874323 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT05874323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04696692 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT04746118 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06474104 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT06564961 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT05338099 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06220721 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05990296 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05889156 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT06620029 — Predictive Biomarker (PRD): BMX mRNA
Genes: BMX
Study NCT06620029 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05906953 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study NCT05224960 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT06138964 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study NCT06138964 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study NCT06561620 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02860559 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT05159778 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05159778 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05173259 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study NCT06114615 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05189613 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT05016778 — Predictive Biomarker (PRD): GPRC5D mRNA
Genes: GPRC5D
Study NCT04501159 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05834309 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06467617 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT05604040 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06453044 — Predictive Biomarker (PRD): CD79B mRNA
Genes: CD79B; B29; IGB
Study NCT05831553 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05831553 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT05313022 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06333314 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT06223750 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05327621 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT05327621 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT06049082 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT05603884 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04886401 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05805566 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06644469 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05843682 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06704620 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06116149 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06586658 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT05080946 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT05080946 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study NCT05080946 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study NCT04715191 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT04715191 — Predictive Biomarker (PRD): IL15 mRNA
Genes: IL15
Study NCT04715191 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): IL21 mRNA
Genes: IL21
Study NCT06734585 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT06734533 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06734533 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06734533 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT06734533 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06735560 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT06736080 — Predictive Biomarker (PRD): UNC13D mRNA
Genes: UNC13D
Study NCT06736080 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT06444217 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT06235801 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT06525675 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06525675 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06228924 — Predictive Biomarker (PRD): PKP2 mRNA
Genes: PKP2
Study NCT05259150 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05244707 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05244707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05244707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04557865 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study NCT04557865 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04557865 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT04557865 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT04557865 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study NCT04557865 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT05728515 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT04352296 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06009653 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05865990 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT05292950 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study NCT06660108 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study NCT05496959 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05446428 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05446428 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study NCT05446428 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT05446428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06471036 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05639894 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04795726 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05290688 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05324358 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT06116292 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT06627894 — Predictive Biomarker (PRD): GDA mRNA
Genes: GDA; KIAA1258
Study NCT06627894 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06429891 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT06200649 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06507059 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05232006 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT06405152 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study NCT05583422 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study NCT05498545 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05592665 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05592665 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06104033 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT05902078 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05662696 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06131333 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT05151120 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT04844827 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04844827 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06093100 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04616248 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06568835 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05244109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05244109 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT05246982 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05246982 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05744570 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study NCT06428825 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05230160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00378235 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT04687358 — Safety Biomarker (SAF): Interleukin 1
Study NCT06604611 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06604611 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06597045 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06597045 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06587711 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04987489 — Surrogate Endpoint (SUR): Hemoglobin response rate
Study NCT05393401 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05638022 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT04736927 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05705882 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06527794 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06592716 — Monitoring Biomarker (MOI): Cell-free HPV DNA
Study NCT06678373 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06704893 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06706557 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06706557 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06548529 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06704815 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06056596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05518903 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT04654585 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT05838404 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05166915 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04778345 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05761054 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT06478277 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT06478277 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT05248451 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT05978180 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT05978180 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06668090 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06614465 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study NCT05943457 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study NCT04323826 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT06494930 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05794906 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06621927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06659406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06659406 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT04813653 — Predictive Biomarker (PRD): PPIA mRNA
Genes: PPIA; CYPA
Study NCT02078635 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05120635 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT04841811 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06392295 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00496236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04813627 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05260528 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study NCT06284460 — Safety Biomarker (SAF): RAS pathway
Study NCT06622629 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT06618560 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT06618560 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05563675 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT05035576 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study NCT06461182 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT04970550 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06441045 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05312801 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT06048770 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05896163 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06098898 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06652139 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT05954845 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study NCT05954845 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study NCT05954845 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study NCT05757843 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05995015 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06652061 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06651320 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05401864 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT05401864 — Predictive Biomarker (PRD): CALR mRNA
Genes: CALR; CRTC
Study NCT05401864 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study NCT05329441 — Predictive Biomarker (PRD): TNR mRNA
Genes: TNR
Study NCT05634252 — Predictive Biomarker (PRD): MC1R mRNA
Genes: MC1R; MSHR
Study NCT06137833 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05350865 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05447819 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06374836 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04740489 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05482074 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06217094 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04733768 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06476314 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05601414 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06239272 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT06239272 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT06239272 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT06224309 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT06470399 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01471314 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT04849741 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT05631509 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT05631509 — Predictive Biomarker (PRD): ADGRG2 mRNA
Genes: ADGRG2; GPR64; HE6; TM7LN2
Study NCT05440409 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05797948 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05797948 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT04769050 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06506266 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT06585488 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04784715 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04784715 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05449964 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT06527469 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT05385510 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05068752 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05068752 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT05510765 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05315362 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05443230 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06205849 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT04827368 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study NCT04827368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05647395 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06417320 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05455593 — Predictive Biomarker (PRD): SP4 mRNA
Genes: SP4
Study NCT06340750 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT05117294 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05425550 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04787445 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT06321289 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06321289 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study NCT06321289 — Predictive Biomarker (PRD): CIITA mRNA
Genes: CIITA; MHC2TA
Study NCT06321289 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT05638815 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT06035094 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04576988 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT05263466 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05869708 — Predictive Biomarker (PRD): DARS1 mRNA
Genes: DARS1; DARS; PIG40
Study NCT04984473 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05462054 — Predictive Biomarker (PRD): STXBP1 mRNA
Genes: STXBP1; UNC18A
Study NCT04959435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06262581 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT05967767 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT06411600 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06411600 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor