TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33441772 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 32369032 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33727066 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 33727066 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33727066 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32936795 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33537776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33537776 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 33537776 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 33537776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33037580 — Surrogate Endpoint (SUR): Serum calcium
Study 33037580 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 35237893 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35237893 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 35501178 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33164276 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 32894140 — Predictive Biomarker (PRD): SDHA mRNA
Genes: SDHA; SDH2; SDHF
Study 32894140 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 32894140 — Safety Biomarker (SAF): Cytochrome c
Study 32894140 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 32393193 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32393193 — Safety Biomarker (SAF): BDNF
Study 36096864 — Surrogate Endpoint (SUR): Blood pressure
Study 34033935 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 35028968 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 35028968 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35247922 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 35247922 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 35934913 — Predictive Biomarker (PRD): SAMHD1 mRNA
Genes: SAMHD1; MOP5
Study 32378261 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 32572955 — Safety Biomarker (SAF): IL-6 and IL-10
Study 32572955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32351591 — Surrogate Endpoint (SUR): Serum triglycerides
Study 34110925 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 34799753 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32385815 — Safety Biomarker (SAF): Reactive oxygen species
Study 33025652 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33025652 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 33025652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 610148118 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 34225066 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34225066 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34225066 — Predictive Biomarker (PRD): Hormone receptor
Study 35320619 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35320619 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33610954 — Surrogate Endpoint (SUR): Blood pressure
Study 32605005 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32605005 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 32721549 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 32515246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32515246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36282186 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 36282186 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35317637 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 33283767 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33283767 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32547310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35708951 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 32563599 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 36246136 — Surrogate Endpoint (SUR): Bone mineral density
Study 33399016 — Surrogate Endpoint (SUR): Blood pressure
Study 35226532 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 34349841 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 32682457 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33288325 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 33023671 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33704435 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33982936 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 36078648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33205064 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 33205064 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 34391872 — Surrogate Endpoint (SUR): Total kidney volume
Study 32066598 — Surrogate Endpoint (SUR): Serum potassium
Study 34853883 — Surrogate Endpoint (SUR): Bone mineral density
Study 32466016 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 34325645 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35161508 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34580638 — Surrogate Endpoint (SUR): Bone mineral density
Study 35254967 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 32848379 — Surrogate Endpoint (SUR): Blood pressure
Study 33217147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34002707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33941941 — Surrogate Endpoint (SUR): Blood pressure
Study 34993836 — Surrogate Endpoint (SUR): Blood pressure
Study 32574096 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33653749 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 32580710 — Surrogate Endpoint (SUR): Blood pressure
Study 35012310 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33306213 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 33306213 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 33306213 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 32211084 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34918714 — Surrogate Endpoint (SUR): Blood pressure
Study 34918714 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32894102 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34861767 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 34861767 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 34861767 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 34861767 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study 34861767 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 34861767 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36137670 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32591103 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 32133391 — Predictive Biomarker (PRD): Hormone receptor
Study 35411792 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 34942595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33065552 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 35406083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33278859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32066487 — Surrogate Endpoint (SUR): Blood pressure
Study 32066487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32066487 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33962504 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33962504 — Predictive Biomarker (PRD): FBXO8 mRNA
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 35218194 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 34148146 — Safety Biomarker (SAF): BDNF
Study 34148146 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 33109190 — Surrogate Endpoint (SUR): Blood pressure
Study 35404684 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35266296 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 35320921 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 32852139 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 32976051 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 34346827 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32958697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33334450 — Surrogate Endpoint (SUR): Blood pressure
Study 35689890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35689890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35689890 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 35689890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35689890 — Surrogate Endpoint (SUR): Blood pressure
Study 33075197 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33887445 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 32755035 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 34256413 — Safety Biomarker (SAF): Hyaluronic acid
Study 33010038 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34264000 — Surrogate Endpoint (SUR): Blood pressure
Study 33955183 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 616774451 — Surrogate Endpoint (SUR): Blood pressure
Study 32568876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36102236 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 34499904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32279416 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 32279416 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 36316511 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 32376724 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 35590219 — Predictive Biomarker (PRD): KHK mRNA
Genes: KHK
Study 33542908 — Surrogate Endpoint (SUR): Blood pressure
Study 33894583 — Predictive Biomarker (PRD): DCT mRNA
Genes: DCT; TYRP2
Study 35781044 — Surrogate Endpoint (SUR): Blood pressure
Study 32334632 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 32571411 — Surrogate Endpoint (SUR): Blood pressure
Study 35089798 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35089798 — Surrogate Endpoint (SUR): Blood pressure
Study 34131157 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 35441463 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35441463 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 37119361 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33674633 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 33674633 — Monitoring Biomarker (MOI): miR-29a
Genes: MIR29A
Study 34537805 — Surrogate Endpoint (SUR): Blood pressure
Study 34756997 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 34221381 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 34221381 — Surrogate Endpoint (SUR): Total kidney volume
Study 34221381 — Surrogate Endpoint (SUR): Blood pressure
Study 35830361 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33827478 — Surrogate Endpoint (SUR): Serum sodium
Study 35407483 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 36216304 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 36216304 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 32675599 — Surrogate Endpoint (SUR): Bone mineral density
Study 34636474 — Safety Biomarker (SAF): Hyaluronic acid
Study 36054180 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36054180 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 34157357 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 35941553 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 32324902 — Predictive Biomarker (PRD): SLC5A8 mRNA
Genes: SLC5A8; AIT; SMCT; SMCT1
Study 32516351 — Surrogate Endpoint (SUR): Blood pressure
Study 32221489 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 34425869 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34425869 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34425869 — Predictive Biomarker (PRD): Hormone receptor
Study 35459911 — Predictive Biomarker (PRD): A2M mRNA
Genes: A2M; CPAMD5; FWP007
Study 36296939 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 33755118 — Surrogate Endpoint (SUR): Blood pressure
Study 33266499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33266499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33266499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33531690 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 32722799 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 32722799 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34105796 — Surrogate Endpoint (SUR): Bone mineral density
Study 32516725 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 32516725 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 34371826 — Predictive Biomarker (PRD): RASGRP1 mRNA
Genes: RASGRP1; RASGRP
Study 34371826 — Predictive Biomarker (PRD): BIN1 mRNA
Genes: BIN1; AMPHL
Study 34371826 — Predictive Biomarker (PRD): LEF1 mRNA
Genes: LEF1
Study 34371826 — Predictive Biomarker (PRD): ANXA6 mRNA
Genes: ANXA6; ANX6
Study 34371826 — Predictive Biomarker (PRD): LRRN3 mRNA
Genes: LRRN3; Nbla10363; UNQ194/PRO220
Study 34371826 — Predictive Biomarker (PRD): PRKCQ mRNA
Genes: PRKCQ; PRKCT
Study 35405087 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32894227 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 36344933 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33164978 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32100261 — Monitoring Biomarker (MOI): HBV DNA
Study 35816301 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32795310 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 32795310 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 35180696 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 35158207 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34371884 — Predictive Biomarker (PRD): TXNIP mRNA
Genes: TXNIP; VDUP1
Study 34371884 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 34371884 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 34371884 — Predictive Biomarker (PRD): MLXIP mRNA
Genes: MLXIP; BHLHE36; KIAA0867; MIR; MONDOA
Study 34371884 — Predictive Biomarker (PRD): MAFF mRNA
Genes: MAFF
Study 34371884 — Predictive Biomarker (PRD): MAFG mRNA
Genes: MAFG
Study 34371884 — Predictive Biomarker (PRD): NCF1 mRNA
Genes: NCF1; NOXO2; SH3PXD1A
Study 34371884 — Predictive Biomarker (PRD): FTH1 mRNA
Genes: FTH1; FTH; FTHL6; OK/SW-cl.84; PIG15
Study 34371884 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 34371884 — Predictive Biomarker (PRD): TKT mRNA
Genes: TKT
Study 36006634 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33641601 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 33641601 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 33641601 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 33641601 — Surrogate Endpoint (SUR): Serum calcium
Study 33641601 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 33641601 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34919613 — Surrogate Endpoint (SUR): Blood pressure
Study 32067040 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32358544 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32358544 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 34597366 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 33655432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34048947 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32465052 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 33985364 — Surrogate Endpoint (SUR): Blood pressure
Study 33985364 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35658056 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 33201520 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32599655 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 33239044 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 33019798 — Surrogate Endpoint (SUR): Blood pressure
Study 33989025 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32804188 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34648082 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 33402230 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 34028504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32201120 — Surrogate Endpoint (SUR): Blood pressure
Study 36109142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36109142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36109142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35201920 — Safety Biomarker (SAF): Reactive oxygen species
Study 36359816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37715688 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 33397395 — Surrogate Endpoint (SUR): Blood pressure
Study 33397395 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 32513313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32513313 — Surrogate Endpoint (SUR): Blood pressure
Study 36018224 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 36018224 — Predictive Biomarker (PRD): Liver iron
Study 33528102 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 35942633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35942633 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34105213 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 35172870 — Predictive Biomarker (PRD): MXD1 mRNA
Genes: MXD1; MAD
Study 34033301 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 32265129 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33415354 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34020929 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 32611442 — Surrogate Endpoint (SUR): Blood pressure
Study 32611442 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33709262 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33709262 — Surrogate Endpoint (SUR): Blood pressure
Study 32065311 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33422683 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC