TrialPanorama/TrialPanorama-database huggingface dataset:
Study 34224684 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34224684 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34226282 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 34227407 — Surrogate Endpoint (SUR): Blood pressure
Study 34229125 — Surrogate Endpoint (SUR): Blood pressure
Study 34229186 — Predictive Biomarker (PRD): CRHBP mRNA
Genes: CRHBP; CRFBP
Study 34229186 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 34229186 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 34229268 — Safety Biomarker (SAF): Reactive oxygen species
Study 34229290 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 34229714 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 34229714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34230007 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 34230007 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 34230007 — Predictive Biomarker (PRD): KDM1A mRNA
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study 34230007 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study 34230013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34230013 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34231877 — Surrogate Endpoint (SUR): Bone mineral density
Study 34232223 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34232493 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 34233996 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 34236245 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 34236245 — Surrogate Endpoint (SUR): Blood pressure
Study 34236339 — Predictive Biomarker (PRD): CTNND2 mRNA
Genes: CTNND2; NPRAP
Study 34236339 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 34236339 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 34236339 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34236339 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 34236339 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 34236401 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 34236401 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 34237031 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 34237031 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 34237031 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 34237031 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study 34237031 — Predictive Biomarker (PRD): CCDC6 mRNA
Genes: CCDC6; D10S170; TST1
Study 34237166 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 34237166 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 34238024 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 34238299 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 34239811 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34239811 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34242388 — Predictive Biomarker (PRD): PANO1 mRNA
Genes: PANO1; PANO
Study 34242388 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34243799 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 34244298 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 34244670 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34244670 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34245496 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 34245496 — Predictive Biomarker (PRD): NSD1 mRNA
Genes: NSD1; ARA267; KMT3B
Study 34245635 — Predictive Biomarker (PRD): ABCD2 mRNA
Genes: ABCD2; ALD1; ALDL1; ALDR; ALDRP
Study 34246305 — Predictive Biomarker (PRD): GLDC mRNA
Genes: GLDC; GCSP
Study 34246305 — Predictive Biomarker (PRD): BCKDHB mRNA
Genes: BCKDHB
Study 34246305 — Predictive Biomarker (PRD): AASS mRNA
Genes: AASS
Study 34246305 — Predictive Biomarker (PRD): RPL15 mRNA
Genes: RPL15; EC45; TCBAP0781
Study 34246305 — Predictive Biomarker (PRD): AGL mRNA
Genes: AGL; GDE
Study 34246305 — Predictive Biomarker (PRD): PDK2 mRNA
Genes: PDK2; PDHK2
Study 34246305 — Predictive Biomarker (PRD): LDHB mRNA
Genes: LDHB
Study 34246305 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 34246305 — Predictive Biomarker (PRD): PXMP2 mRNA
Genes: PXMP2; PMP22
Study 34246305 — Predictive Biomarker (PRD): OGDH mRNA
Genes: OGDH
Study 34246305 — Predictive Biomarker (PRD): SUCLA2 mRNA
Genes: SUCLA2
Study 34247273 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study 34247489 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 34247489 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study 34247489 — Predictive Biomarker (PRD): miR-135a
Study 34247489 — Predictive Biomarker (PRD): miR-23a-3p
Genes: MIR23A
Study 34248841 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 34248841 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 34248841 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 34248841 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 34248841 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34248841 — Predictive Biomarker (PRD): ADAM9 mRNA
Genes: ADAM9; KIAA0021; MCMP; MDC9; MLTNG
Study 34248841 — Predictive Biomarker (PRD): SEMA3A mRNA
Genes: SEMA3A; SEMAD
Study 34248841 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34248841 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34249690 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 34250397 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 34250397 — Monitoring Biomarker (MOI): Cell-free DNA
Study 34250553 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 34250583 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 34250583 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 34250820 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34251287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34251287 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 34251495 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 34251495 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 34251495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34251495 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 34251540 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 34251540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34251649 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 34251649 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 34251649 — Surrogate Endpoint (SUR): Blood pressure
Study 34251685 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34252066 — Predictive Biomarker (PRD): DARS1 mRNA
Genes: DARS1; DARS; PIG40
Study 34252375 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34252375 — Predictive Biomarker (PRD): Hormone receptor
Study 34252876 — Predictive Biomarker (PRD): PSEN1 mRNA
Genes: PSEN1; AD3; PS1; PSNL1
Study 34253172 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34253565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34253577 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 34253579 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 34253579 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34253587 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 34253595 — Predictive Biomarker (PRD): BRD3 mRNA
Genes: BRD3; KIAA0043; RING3L
Study 34253595 — Predictive Biomarker (PRD): BRD4 mRNA
Genes: BRD4; HUNK1
Study 34253595 — Predictive Biomarker (PRD): BRDT mRNA
Genes: BRDT
Study 34253597 — Predictive Biomarker (PRD): PAK4 mRNA
Genes: PAK4; KIAA1142
Study 34253597 — Safety Biomarker (SAF): Nicotinamide phosphoribosyltransferase
Genes: NAMPT; PBEF; PBEF1
Study 34253597 — Predictive Biomarker (PRD): RICTOR mRNA
Genes: RICTOR; KIAA1999
Study 34253733 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 34253928 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34253928 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 34253928 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 34254126 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 34255063 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 34255353 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 34255535 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34255535 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 34255901 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 34255901 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 34256279 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 34256305 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 34256735 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34257421 — Predictive Biomarker (PRD): GNE mRNA
Genes: GNE; GLCNE
Study 34257421 — Safety Biomarker (SAF): N-acetylneuraminic acid
Study 34258383 — Predictive Biomarker (PRD): TCP1 mRNA
Genes: TCP1; CCT1; CCTA
Study 34260706 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34260823 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34261689 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34261767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34261794 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study 34262299 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 34262694 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study 34263665 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34263738 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 34263738 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 34263738 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34264412 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study 34264412 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 34264743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34265285 — Predictive Biomarker (PRD): HOXA1 mRNA
Genes: HOXA1; HOX1F
Study 34265433 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 34265433 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 34266463 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 34266941 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 34266943 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 34266943 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 34268393 — Predictive Biomarker (PRD): LRRC15 mRNA
Genes: LRRC15; LIB
Study 34268513 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34268623 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 34268711 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34269152 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 34269152 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 34270325 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34271312 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 34272304 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 34272304 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 34272471 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 34273485 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34273485 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 34274071 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34274072 — Surrogate Endpoint (SUR): Blood pressure
Study 34274536 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 34275469 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 34275766 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 34276042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34277393 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34277393 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34277437 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 34278595 — Safety Biomarker (SAF): Human leucocyte antigen
Study 34280258 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 34280257 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 34280257 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 34281912 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 34282409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34282579 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 34282853 — Surrogate Endpoint (SUR): Bone mineral density
Study 34283029 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 34283213 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34283294 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 34284523 — Safety Biomarker (SAF): Interleukin 1
Study 34284523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34285097 — Surrogate Endpoint (SUR): Blood pressure
Study 34286513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34287805 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study 34288271 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34288547 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 34288560 — Surrogate Endpoint (SUR): Probing pocket depth
Study 34289017 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 34289017 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study 34289017 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 34289815 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 34290067 — Predictive Biomarker (PRD): ISM1 mRNA
Genes: ISM1; C20orf82; ISM
Study 34290403 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34291312 — Predictive Biomarker (PRD): PTPN22 mRNA
Genes: PTPN22; PTPN8
Study 34291312 — Predictive Biomarker (PRD): PLEKHA1 mRNA
Genes: PLEKHA1; TAPP1
Study 34291312 — Predictive Biomarker (PRD): RNASET2 mRNA
Genes: RNASET2; RNASE6PL
Study 34291810 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34292174 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 34292185 — Safety Biomarker (SAF): BDNF
Study 34292185 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 34292185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34292185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34292185 — Safety Biomarker (SAF): IL-6 and IL-10
Study 34292324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34292473 — Predictive Biomarker (PRD): ATF4 mRNA
Genes: ATF4; CREB2; TXREB
Study 34292473 — Predictive Biomarker (PRD): ATF6 mRNA
Genes: ATF6
Study 34292473 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 34292473 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 34292473 — Predictive Biomarker (PRD): EIF2AK3 mRNA
Genes: EIF2AK3; PEK; PERK
Study 34292473 — Predictive Biomarker (PRD): HSP90B1 mRNA
Genes: HSP90B1; GRP94; TRA1
Study 34292473 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 34292516 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34293119 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 34293119 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34294152 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34294862 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 34296427 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 34296962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34296962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34297159 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 34297797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34298149 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 34298149 — Surrogate Endpoint (SUR): Serum creatinine
Study 34298554 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 34298554 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34298717 — Monitoring Biomarker (MOI): Cell-free DNA
Study 34300217 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34300217 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 34301808 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34301809 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 34301810 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34302589 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34302760 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34302856 — Surrogate Endpoint (SUR): Blood pressure
Study 34303017 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 34304968 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 34304968 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34305452 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 34305947 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 34307126 — Surrogate Endpoint (SUR): Pathological complete response
Study 34307188 — Predictive Biomarker (PRD): IFNL3
Genes: IL-28B; IL28C
Study 34309174 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 34309174 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 34310027 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 34310436 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 34310745 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 34311211 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34311211 — Predictive Biomarker (PRD): Hormone receptor
Study 34312462 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): IL21 mRNA
Genes: IL21
Study 34312483 — Predictive Biomarker (PRD): TNFRSF18 mRNA
Genes: TNFRSF18; AITR; GITR; UNQ319/PRO364
Study 34312483 — Predictive Biomarker (PRD): TNFSF18 mRNA
Genes: TNFSF18; AITRL; GITRL; TL6; UNQ149/PRO175
Study 34312556 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 34312556 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 34312616 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34313599 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34313599 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34313764 — Surrogate Endpoint (SUR): Bone mineral density
Study 34314483 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 34315519 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34315519 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 34315519 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34315519 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B