TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05049187 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06169111 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04781283 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05584605 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05445063 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT05921877 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT04847635 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT06524440 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05254249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05254249 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT05254249 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT05620264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05910242 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06396624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06396624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06396624 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT06396624 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT06634667 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06635278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06520891 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04902183 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study NCT05442580 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT04853004 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06635798 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04949074 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04718883 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00325299 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT00325299 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05749328 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06272500 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06232213 — Predictive Biomarker (PRD): Protein patched homolog 1
Genes: PTCH1; PTCH
Study NCT06417099 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT04729855 — Predictive Biomarker (PRD): EIF4EBP1 mRNA
Genes: EIF4EBP1
Study NCT04706936 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06297720 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06198751 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04845399 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT04603742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04603742 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study NCT04603742 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01227850 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study NCT05658172 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT05637606 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05195645 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05195645 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05195645 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT05195645 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study NCT05113849 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05248373 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05742282 — Predictive Biomarker (PRD): HAS2 mRNA
Genes: HAS2
Study NCT05580835 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04773067 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04998981 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05458401 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04885413 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05353335 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04709458 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT04118530 — Predictive Biomarker (PRD): HCST mRNA
Genes: HCST; DAP10; KAP10; PIK3AP; UNQ587/PRO1157
Study NCT06478927 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05652751 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04608474 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT05740462 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT05238831 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study NCT05911178 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05075512 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05075512 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05075512 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT05075512 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT05075512 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05075512 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT05168774 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study NCT06342336 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT04591171 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05671848 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study NCT00000683 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06635343 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06635408 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT06477523 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06477523 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT05224856 — Predictive Biomarker (PRD): TP63 mRNA
Genes: TP63; KET; P63; P73H; P73L; TP73L
Study NCT05042531 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study NCT05042531 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT05042531 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study NCT05042531 — Predictive Biomarker (PRD): DOK6 mRNA
Genes: DOK6; DOK5L
Study NCT05042531 — Predictive Biomarker (PRD): PTPN11 mRNA
Genes: PTPN11; PTP2C; SHPTP2
Study NCT05954143 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05954143 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06546852 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06422741 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06422741 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06422741 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06422741 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT05811468 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04702516 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05261373 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04972500 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03999840 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT04698993 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04994626 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study NCT04994626 — Predictive Biomarker (PRD): CD79A mRNA
Genes: CD79A; IGA; MB1
Study NCT04994626 — Predictive Biomarker (PRD): CD79B mRNA
Genes: CD79B; B29; IGB
Study NCT05692869 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06393647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06393647 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study NCT05287997 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT04838678 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05910138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00013585 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT05521412 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05723211 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05175196 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT04717011 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05227287 — Predictive Biomarker (PRD): ADH1A mRNA
Genes: ADH1A; ADH1
Study NCT05465785 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05415228 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05113030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06465147 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06531954 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06531954 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05440747 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT05440747 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04849910 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT04878549 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study NCT04878549 — Predictive Biomarker (PRD): SLAMF8 mRNA
Genes: SLAMF8; BLAME
Study NCT04878549 — Predictive Biomarker (PRD): PSME2 mRNA
Genes: PSME2
Study NCT04878549 — Predictive Biomarker (PRD): WARS1 mRNA
Genes: WARS1; IFI53; WARS; WRS
Study NCT04878549 — Predictive Biomarker (PRD): ALDH1A1 mRNA
Genes: ALDH1A1; ALDC; ALDH1; PUMB1
Study NCT05413720 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT05440864 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05722886 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT05129046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05168462 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06588491 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05422118 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06119815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05587192 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04984005 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04984005 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04976647 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05758103 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT05479318 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03515031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05579470 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study NCT06224777 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT05644548 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00002107 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT06020599 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05858684 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05858684 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04452136 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05914844 — Predictive Biomarker (PRD): HAS2 mRNA
Genes: HAS2
Study NCT04883177 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04883177 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06477666 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study NCT05017077 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05679102 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05379621 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06330727 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06330727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06330727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06330727 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06330727 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05305144 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00002172 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05506566 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT06537674 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06130059 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04862143 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT05367700 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04632069 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05343702 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05918276 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT06317168 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06056778 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT04969250 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05163223 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05163223 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05163223 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06083428 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT06083428 — Safety Biomarker (SAF): Platelet to lymphocyte
Study NCT04812912 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT04812912 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT05308394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06059014 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06375486 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04971720 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT04971720 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study NCT04971720 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT06052527 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06578507 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06195527 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06195527 — Predictive Biomarker (PRD): PDCD1LG2 mRNA
Genes: PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2
Study NCT04211259 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06344468 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05220020 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05354700 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04724317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06122766 — Predictive Biomarker (PRD): NGLY1 mRNA
Genes: NGLY1; PNG1
Study NCT04584372 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06238284 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04744480 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00006154 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT06061237 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05872347 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05872347 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05810350 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05420545 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT04761653 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04761653 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT05427227 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05427227 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT00002334 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06068036 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06120543 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT06120543 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT06120543 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT05147818 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06263075 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00043732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00043732 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study NCT00043732 — Safety Biomarker (SAF): Interleukin 1
Study NCT05512169 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study NCT06552637 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study NCT04897295 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05984602 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05934045 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04896281 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study NCT04627766 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04992260 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05766176 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05932069 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05799755 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04040829 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04040829 — Safety Biomarker (SAF): BDNF
Study NCT05970159 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT06634628 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT05738057 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04903054 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT06215950 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT06786338 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT05846516 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05950698 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04780204 — Monitoring Biomarker (MOI): HBV DNA
Study NCT05913024 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06193421 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study NCT04858516 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06007924 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT06786637 — Predictive Biomarker (PRD): PNOC mRNA
Genes: PNOC; OFQ
Study NCT05553691 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study NCT06783790 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT06783790 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study NCT06783790 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study NCT06783790 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MYH11 mRNA
Genes: MYH11; KIAA0866
Study NCT05469321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04948840 — Predictive Biomarker (PRD): TREM1 mRNA
Genes: TREM1
Study NCT06060587 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT04698980 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT05498467 — Safety Biomarker (SAF): Interleukin 1
Study NCT06786403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05323370 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT05258279 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06508957 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study NCT06508957 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05062486 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD