TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32302717 — Surrogate Endpoint (SUR): Blood pressure
Study 35220948 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 35220948 — Surrogate Endpoint (SUR): Serum potassium
Study 35220948 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33126910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33126910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34382353 — Surrogate Endpoint (SUR): Blood pressure
Study 32641379 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32482626 — Predictive Biomarker (PRD): DSE mRNA
Genes: DSE; SART2
Study 36243020 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 35131486 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35131486 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 34311059 — Predictive Biomarker (PRD): ASPSCR1 mRNA
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 32969717 — Predictive Biomarker (PRD): DHX36 mRNA
Genes: DHX36; DDX36; KIAA1488; MLEL1; RHAU
Study 32969717 — Predictive Biomarker (PRD): MRPL33 mRNA
Genes: MRPL33; C2orf1
Study 32969717 — Predictive Biomarker (PRD): SELE mRNA
Genes: SELE; ELAM1
Study 32969717 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 32969717 — Predictive Biomarker (PRD): BSN mRNA
Genes: BSN; KIAA0434; ZNF231
Study 32969717 — Predictive Biomarker (PRD): ILF3 mRNA
Genes: ILF3; DRBF; MPHOSPH4; NF90
Study 32969717 — Predictive Biomarker (PRD): N4BP2L2 mRNA
Genes: N4BP2L2; CG005; PFAAP5
Study 35466448 — Surrogate Endpoint (SUR): Bone mineral density
Study 35466448 — Surrogate Endpoint (SUR): Serum calcium
Study 33485453 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33838307 — Predictive Biomarker (PRD): LAT2 mRNA
Genes: LAT2; LAB; NTAL; WBS15; WBSCR15; WBSCR5; HSPC046
Study 34290695 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34311441 — Surrogate Endpoint (SUR): Blood pressure
Study 35184471 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 34653608 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 35498888 — Surrogate Endpoint (SUR): Serum creatinine
Study 34990291 — Predictive Biomarker (PRD): TIMM8A mRNA
Genes: TIMM8A; DDP; DDP1; TIM8A
Study 35221215 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 32780643 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35125219 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 34344416 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34344416 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 33602684 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 32701419 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 34153143 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 34153143 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 34153143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34153143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35525971 — Surrogate Endpoint (SUR): Blood pressure
Study 33212063 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 32947644 — Surrogate Endpoint (SUR): Bone mineral density
Study 36027510 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 36027510 — Surrogate Endpoint (SUR): Blood pressure
Study 35266158 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 35785794 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 36112019 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32603408 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 34605959 — Surrogate Endpoint (SUR): Blood pressure
Study 35806857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33331570 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 33331570 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 33331570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33331570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33331570 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 33331570 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34354699 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 34354699 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 32960889 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 32712155 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 32712155 — Predictive Biomarker (PRD): miR-16-5p
Study 32712155 — Safety Biomarker (SAF): miR-16
Study 32712155 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-20a
Genes: MIR20A
Study 32712155 — Predictive Biomarker (PRD): miR-21-5p
Genes: MIR21
Study 32712155 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 32712155 — Safety Biomarker (SAF): miR-93-5p
Genes: MIR93
Study 32712155 — Predictive Biomarker (PRD): miR-93
Genes: MIR93
Study 32712155 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 34536433 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34536433 — Safety Biomarker (SAF): BDNF
Study 34119270 — Surrogate Endpoint (SUR): Blood pressure
Study 33452064 — Surrogate Endpoint (SUR): Blood pressure
Study 32122449 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 36303113 — Surrogate Endpoint (SUR): Blood pressure
Study 36303113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34174842 — Surrogate Endpoint (SUR): Blood pressure
Study 34174842 — Surrogate Endpoint (SUR): Serum creatinine
Study 33588822 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 32405735 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 32495298 — Surrogate Endpoint (SUR): Bone mineral density
Study 33350776 — Surrogate Endpoint (SUR): Blood pressure
Study 616388369 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32610573 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 35944773 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35944773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36252131 — Surrogate Endpoint (SUR): Blood pressure
Study 34378860 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33090908 — Surrogate Endpoint (SUR): Blood pressure
Study 33597521 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32781481 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 32781481 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 34907823 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 34907823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34907823 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 34907823 — Surrogate Endpoint (SUR): Bone mineral density
Study 35273351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35405480 — Predictive Biomarker (PRD): CYP1A1 mRNA
Genes: CYP1A1
Study 35405480 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 35405480 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study 35984511 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33000332 — Surrogate Endpoint (SUR): Blood pressure
Study 33413355 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35039254 — Surrogate Endpoint (SUR): Serum creatinine
Study 35129503 — Predictive Biomarker (PRD): LAMB2 mRNA
Genes: LAMB2; LAMS
Study 33328160 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 32379676 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 32383271 — Surrogate Endpoint (SUR): Blood pressure
Study 34157617 — Surrogate Endpoint (SUR): Pathological complete response
Study 33300239 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33300239 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33300239 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 33300239 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 33300239 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32894540 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 33458967 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35938913 — Predictive Biomarker (PRD): NAAA mRNA
Genes: NAAA; ASAHL; PLT
Study 32011447 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 33833401 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 32432914 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33085021 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 32759183 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 32759183 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 35365371 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 35365371 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 35365371 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 35365371 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35822881 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33443719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 35618326 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 35715871 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 35122096 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35590011 — Predictive Biomarker (PRD): BLM mRNA
Genes: BLM; RECQ2; RECQL3
Study 33217117 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 36280012 — Surrogate Endpoint (SUR): Blood pressure
Study 70634317 — Surrogate Endpoint (SUR): Serum hemoglobin A1C
Study 70634317 — Surrogate Endpoint (SUR): Serum creatinine
Study 34142392 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34142392 — Surrogate Endpoint (SUR): Blood pressure
Study 32938280 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34544429 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 36127630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32591464 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35844438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35844438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35844438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35844438 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 35844438 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32629117 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 34302228 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 33382828 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 33382828 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 35005871 — Safety Biomarker (SAF): Hyaluronic acid
Study 33470637 — Safety Biomarker (SAF): Interleukin 1
Study 35920045 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35920045 — Surrogate Endpoint (SUR): Blood pressure
Study 34090451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32394658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32394658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32394658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34450050 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 34450050 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32466231 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 32439248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35357103 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32740754 — Surrogate Endpoint (SUR): Blood pressure
Study 33044710 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35296044 — Surrogate Endpoint (SUR): Blood pressure
Study 36012990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36012990 — Surrogate Endpoint (SUR): Blood pressure
Study 32954487 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 33049713 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 32603336 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35723225 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 34684508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 35538539 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35538539 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 35538539 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 35538539 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 35538539 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 35538539 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 36074965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33705355 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36396999 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 36396999 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 36524101 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study 34097130 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 34826125 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34162720 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 32289676 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 36513447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33583033 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 33583033 — Predictive Biomarker (PRD): TM6SF2 mRNA
Genes: TM6SF2
Study 33583033 — Predictive Biomarker (PRD): MBOAT7 mRNA
Genes: MBOAT7; BB1; LENG4; OACT7
Study 33583033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36399909 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 35213289 — Predictive Biomarker (PRD): ACY3 mRNA
Genes: ACY3; ASPA2
Study 35213289 — Surrogate Endpoint (SUR): Blood pressure
Study 33439315 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32229597 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 33962579 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 33389715 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 34468696 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32277617 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 32277617 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 32277617 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 32277617 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 32277617 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32277617 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32277617 — Safety Biomarker (SAF): IL-6 and IL-10
Study 34353070 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34353070 — Surrogate Endpoint (SUR): Serum creatinine
Study 32106837 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 35362891 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 35506164 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34625847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34625847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34625847 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 34168210 — Surrogate Endpoint (SUR): Bone mineral density
Study 32524226 — Surrogate Endpoint (SUR): Blood pressure
Study 32524226 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 37516844 — Surrogate Endpoint (SUR): Blood pressure
Study 34962595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34962595 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33423021 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34008856 — Predictive Biomarker (PRD): XPC mRNA
Genes: XPC; XPCC
Study 34008856 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 34008856 — Predictive Biomarker (PRD): RPA1 mRNA
Genes: RPA1; REPA1; RPA70
Study 35665745 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32032997 — Surrogate Endpoint (SUR): Bone mineral density
Study 32462921 — Surrogate Endpoint (SUR): Blood pressure
Study 32784117 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 32784117 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 35975297 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35975297 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 33517683 — Surrogate Endpoint (SUR): Blood pressure
Study 33372830 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 34811505 — Predictive Biomarker (PRD): HOXD8 mRNA
Genes: HOXD8; HOX4E
Study 34811505 — Predictive Biomarker (PRD): POU4F1 mRNA
Genes: POU4F1; BRN3A; RDC1
Study 33289598 — Surrogate Endpoint (SUR): Serum creatinine
Study 34759131 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 32396519 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35718871 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34569334 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35803172 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 34426648 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34775948 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32955200 — Surrogate Endpoint (SUR): Plasma ammonia
Study 33515536 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 33788024 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32989470 — Surrogate Endpoint (SUR): Bone mineral density
Study 35642923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 32388179 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 32430771 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 33588527 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 33446240 — Predictive Biomarker (PRD): RORA
Genes: RZRA; ROR1; ROR2; ROR3; NR1F1; ROR-alpha; RORalpha; RORa1
Study 32450344 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32398324 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 32398324 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 32398324 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study 33059419 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 36431314 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34429197 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35505122 — Surrogate Endpoint (SUR): Blood pressure
Study 32156749 — Predictive Biomarker (PRD): SQSTM1 mRNA
Genes: SQSTM1; ORCA; OSIL
Study 32719355 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC