TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33881115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33881115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33881115 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33881115 — Surrogate Endpoint (SUR): Serum uric acid
Study 36424580 — Surrogate Endpoint (SUR): Bone mineral density
Study 32070417 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 35241469 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35241469 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35241469 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 33587402 — Surrogate Endpoint (SUR): Blood pressure
Study 36038262 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32664946 — Surrogate Endpoint (SUR): Bone mineral density
Study 32265508 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 33687763 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33356487 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 33773120 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 33773120 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 32546647 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 35925752 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 35925752 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32192644 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 32192644 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35236763 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 32930386 — Predictive Biomarker (PRD): MPST mRNA
Genes: MPST; TST2
Study 32903140 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 34692725 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 34692725 — Predictive Biomarker (PRD): TM6SF2 mRNA
Genes: TM6SF2
Study 34692725 — Predictive Biomarker (PRD): MBOAT7 mRNA
Genes: MBOAT7; BB1; LENG4; OACT7
Study 34692725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33925277 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33836800 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study 33093598 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 33093598 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 32951731 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 32441833 — Surrogate Endpoint (SUR): Serum testosterone
Study 36450546 — Surrogate Endpoint (SUR): Blood pressure
Study 35368605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37821187 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 32353115 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 35258750 — Surrogate Endpoint (SUR): Blood pressure
Study 36332361 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33176071 — Predictive Biomarker (PRD): VASH1 mRNA
Genes: VASH1; KIAA1036; VASH
Study 33843667 — Surrogate Endpoint (SUR): Blood pressure
Study 33843667 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 33743737 — Predictive Biomarker (PRD): PMM2 mRNA
Genes: PMM2
Study 35195015 — Surrogate Endpoint (SUR): Blood pressure
Study 35312016 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35312016 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 35312016 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 35312016 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35312016 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35337389 — Surrogate Endpoint (SUR): Blood pressure
Study 36153530 — Surrogate Endpoint (SUR): Blood pressure
Study 33186500 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34593374 — Surrogate Endpoint (SUR): Blood pressure
Study 34686614 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 34153529 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 33524994 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 35910832 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35910832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32352341 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study 32352341 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 32352341 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 32352341 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32352341 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 32352341 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 33319250 — Predictive Biomarker (PRD): IGF2 mRNA
Genes: IGF2; PP1446
Study 33319250 — Predictive Biomarker (PRD): PEG3 mRNA
Genes: PEG3; KIAA0287; ZSCAN24
Study 33319250 — Predictive Biomarker (PRD): BLCAP mRNA
Genes: BLCAP; BC10
Study 33319250 — Predictive Biomarker (PRD): DLX5 mRNA
Genes: DLX5
Study 33992897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33992897 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32796259 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 35986498 — Surrogate Endpoint (SUR): Blood pressure
Study 35986498 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 33119948 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 32996171 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 32996171 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 32996171 — Surrogate Endpoint (SUR): Blood pressure
Study 32129161 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34034262 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 33487505 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33393630 — Predictive Biomarker (PRD): PLA2G2D mRNA
Genes: PLA2G2D; SPLASH
Study 33393630 — Predictive Biomarker (PRD): PLA2G4A mRNA
Genes: PLA2G4A; CPLA2; PLA2G4
Study 33393630 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 34826225 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study 32663379 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33407413 — Surrogate Endpoint (SUR): Blood pressure
Study 33404656 — Surrogate Endpoint (SUR): Serum uric acid
Study 34480096 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35585937 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 32091672 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 32091672 — Surrogate Endpoint (SUR): Serum creatinine
Study 32243651 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 35998706 — Surrogate Endpoint (SUR): Blood pressure
Study 33896627 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 36106673 — Predictive Biomarker (PRD): MAP3K10 mRNA
Genes: MAP3K10; MLK2; MST
Study 34922649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34922649 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34922649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32333540 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 35512824 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 35512824 — Predictive Biomarker (PRD): FANCA mRNA
Genes: FANCA; FAA; FACA; FANCH
Study 33473174 — Surrogate Endpoint (SUR): Blood pressure
Study 32683645 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 34048083 — Surrogate Endpoint (SUR): Bone mineral density
Study 32333159 — Surrogate Endpoint (SUR): Blood pressure
Study 32994531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34497646 — Surrogate Endpoint (SUR): Blood pressure
Study 33305625 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 35500453 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 35500453 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 34336612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34336612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34336612 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 34336612 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34336612 — Safety Biomarker (SAF): IL-6 and IL-10
Study 34252115 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 36208978 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34547400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35466449 — Surrogate Endpoint (SUR): Serum calcium
Study 35466449 — Surrogate Endpoint (SUR): Urinary oxalate
Study 33760791 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 32758298 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32758298 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32758298 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34940059 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 34036235 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34036235 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32272024 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 34149004 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 34149004 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 34149004 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study 34149004 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 32295531 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 35172875 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 33025342 — Surrogate Endpoint (SUR): Blood pressure
Study 33327255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33327255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35304275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35304275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35304275 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32847731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33935064 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 36087008 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study 35547000 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33899090 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33899090 — Surrogate Endpoint (SUR): Blood pressure
Study 32192799 — Surrogate Endpoint (SUR): Blood pressure
Study 32192799 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32698681 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32223566 — Surrogate Endpoint (SUR): Serum creatinine
Study 33446284 — Surrogate Endpoint (SUR): Blood pressure
Study 32835877 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32835877 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 33001138 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35501887 — Surrogate Endpoint (SUR): Blood pressure
Study 34743379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34743379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34743379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34737452 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34737452 — Predictive Biomarker (PRD): Hormone receptor
Study 34043280 — Predictive Biomarker (PRD): Anti-acetylcholine receptor antibody
Study 32539893 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 32539893 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 35014145 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 33967075 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 32394855 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 35251561 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-20a
Genes: MIR20A
Study 35251561 — Safety Biomarker (SAF): miR-93-5p
Genes: MIR93
Study 35251561 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-125b
Study 32020813 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35109577 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 35109577 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 32224082 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34732509 — Surrogate Endpoint (SUR): Serum potassium
Study 35130054 — Surrogate Endpoint (SUR): Blood pressure
Study 33200428 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33214094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33214094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33509742 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34535714 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 33163057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33163057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33163057 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 33163057 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33368858 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33368858 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32876107 — Surrogate Endpoint (SUR): Bone mineral density
Study 32246765 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34563097 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 35234868 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35490395 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 33864595 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33864595 — Surrogate Endpoint (SUR): Blood pressure
Study 34385507 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 34385507 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 34385507 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 34866163 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 34214736 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 34214736 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36008895 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 36008895 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 36008895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36008895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36008895 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 33523907 — Predictive Biomarker (PRD): ATG16L2 mRNA
Genes: ATG16L2; WDR80
Study 33523907 — Predictive Biomarker (PRD): ACSL5 mRNA
Genes: ACSL5; ACS5; FACL5; UNQ633/PRO1250
Study 33523907 — Predictive Biomarker (PRD): MAP1LC3A mRNA
Genes: MAP1LC3A
Study 33523907 — Predictive Biomarker (PRD): MAPKAPK3 mRNA
Genes: MAPKAPK3
Study 33523907 — Predictive Biomarker (PRD): PLXNB2 mRNA
Genes: PLXNB2; KIAA0315
Study 34520104 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34520104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34520104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34520104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34520104 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 32926573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33048300 — Predictive Biomarker (PRD): CD6 mRNA
Genes: CD6
Study 35843465 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35148195 — Safety Biomarker (SAF): Reactive oxygen species
Study 35148195 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36341230 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32386521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32386521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32386521 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33779938 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32341031 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 32341031 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 32341031 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32341031 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study 32341031 — Predictive Biomarker (PRD): NCOA2 mRNA
Genes: NCOA2; BHLHE75; SRC2; TIF2
Study 32341031 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 34775518 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 33351921 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 33351921 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33351921 — Surrogate Endpoint (SUR): Bone mineral density
Study 35717989 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32445215 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 32445215 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 34898943 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32514820 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 32285809 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 35899435 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 34063665 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 34574676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34574676 — Safety Biomarker (SAF): Reactive oxygen species
Study 32891607 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 32891607 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32891607 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 34405423 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 34011271 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 33037808 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 35118156 — Safety Biomarker (SAF): Hyaluronic acid
Study 34001168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34001168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33876259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32545223 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33735670 — Surrogate Endpoint (SUR): Blood pressure
Study 32569102 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34973853 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32244279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 32710888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32710888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2