TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04961996 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04961996 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06531070 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study NCT05640999 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study NCT05640999 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT06308159 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT06308159 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study NCT05918094 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06337669 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT05996107 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05996107 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06069427 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06069427 — Safety Biomarker (SAF): BDNF
Study NCT06421181 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05937165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05937165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06508463 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study NCT06040944 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05598502 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05704634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05704634 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05704634 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study NCT04895137 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04778046 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT06668935 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT05095376 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT06595108 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT06669403 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT05442515 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05442515 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT05832931 — Surrogate Endpoint (SUR): Serum calcium
Study NCT06677060 — Surrogate Endpoint (SUR): Serum potassium
Study NCT05723172 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05107700 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT05552755 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT06681870 — Predictive Biomarker (PRD): CLDN6 mRNA
Genes: CLDN6; UNQ757/PRO1488
Study NCT06693284 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT05931042 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06578533 — Surrogate Endpoint (SUR): Serum potassium
Study NCT05768360 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study NCT05768360 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study NCT05768360 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study NCT06776055 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT06776055 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04715529 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT06776458 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06776458 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06776458 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06776458 — Safety Biomarker (SAF): BDNF
Study NCT04959981 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT04734730 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT04824092 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05691517 — Pharmacodynamic Biomarker (PDY): DNA topoisomerase I
Genes: TOP1
Study NCT05372640 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05757206 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT04367675 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04367675 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT06084884 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT06059716 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study NCT05081206 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05993078 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05564962 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06110208 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT04890470 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT06580015 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05575089 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT04602117 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06083246 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT06282575 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06282575 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06502691 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study NCT05020639 — Predictive Biomarker (PRD): IKZF1 mRNA
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study NCT05020639 — Predictive Biomarker (PRD): IKZF3 mRNA
Genes: IKZF3; ZNFN1A3
Study NCT04713163 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04703426 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06293729 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study NCT06293729 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04028700 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT05534802 — Predictive Biomarker (PRD): ARNT mRNA
Genes: ARNT; BHLHE2
Study NCT05534802 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study NCT06116682 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05079828 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04928846 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05032196 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT04823442 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study NCT04823442 — Predictive Biomarker (PRD): ADRB3 mRNA
Genes: ADRB3; ADRB3R; B3AR
Study NCT06410014 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study NCT05554237 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study NCT05554237 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT04962867 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT06522360 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05721521 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04924660 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT06034405 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT06065748 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06065748 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06065748 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05996003 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT05996003 — Surrogate Endpoint (SUR): Skeletal muscle dystrophin
Study NCT05794412 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04320342 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05481879 — Predictive Biomarker (PRD): DMPK mRNA
Genes: DMPK; DM1PK; MDPK
Study NCT06361589 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03939416 — Predictive Biomarker (PRD): POLD1 mRNA
Genes: POLD1; POLD
Study NCT06106828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05634369 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05280353 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT06719804 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study NCT06725264 — Predictive Biomarker (PRD): TYK2 mRNA
Genes: TYK2
Study NCT04605549 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05892328 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05638009 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06490536 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06490536 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06304233 — Predictive Biomarker (PRD): DISC1 mRNA
Genes: DISC1; KIAA0457
Study NCT06467344 — Predictive Biomarker (PRD): ABCA4 mRNA
Genes: ABCA4; ABCR
Study NCT06334965 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study NCT06451159 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05682976 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study NCT05682976 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT05682976 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT05978622 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05978622 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05376800 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT04993677 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT05741385 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT05741385 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT05741385 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT05741385 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT06152809 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04762979 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT04762979 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05269446 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT06407674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06421571 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04597385 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study NCT06423352 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study NCT06423352 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05003258 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05003258 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06174766 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05902598 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study NCT06756828 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06756828 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT05629351 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06445322 — Predictive Biomarker (PRD): ABCA4 mRNA
Genes: ABCA4; ABCR
Study NCT05456984 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05456984 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04952129 — Predictive Biomarker (PRD): SELENOP mRNA
Genes: SELENOP; SELP; SEPP1
Study NCT06756932 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05387564 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study NCT05724121 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05724121 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05947877 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT05177822 — Safety Biomarker (SAF): Interleukin 1
Study NCT06304298 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT06304298 — Safety Biomarker (SAF): Platelet to lymphocyte
Study NCT05882058 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study NCT05165160 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04248127 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study NCT05419596 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT05419596 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study NCT05419596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05419596 — Predictive Biomarker (PRD): TREM2 mRNA
Genes: TREM2
Study NCT04909866 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT06143046 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06209710 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00002359 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06430450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06430450 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study NCT06430450 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT05552001 — Predictive Biomarker (PRD): CBR1 mRNA
Genes: CBR1; CBR; CRN; SDR21C1
Study NCT05038306 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study NCT06655480 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT06244771 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05839951 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT05408845 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06588322 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06588322 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06670196 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06670196 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04499924 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05502237 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05502237 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05140694 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05613036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT05613036 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT06264921 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCNE1 mRNA
Genes: CCNE1; CCNE
Study NCT06619093 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT06619093 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT05269667 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT06530199 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT06434181 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT05272475 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT06310421 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT06619509 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT06694311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06694311 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT06694311 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT05038774 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06683612 — Predictive Biomarker (PRD): LPAR1 mRNA
Genes: LPAR1; EDG2; LPA1
Study NCT06700538 — Predictive Biomarker (PRD): INHBE mRNA
Genes: INHBE
Study NCT06746688 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06746688 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05375227 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT06772779 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06772844 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05375448 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT06255028 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06184646 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05034419 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study NCT05749978 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06775548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06775548 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT06775548 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06775548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06776835 — Predictive Biomarker (PRD): PIWIL4 mRNA
Genes: PIWIL4; HIWI2; PIWI
Study NCT06172127 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06776757 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study NCT02432417 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02432417 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06470971 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06470971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06777264 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06043427 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04824794 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT06191393 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03434548 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT06350097 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06350097 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05404048 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06727227 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05741372 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study NCT05741372 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study NCT05741372 — Predictive Biomarker (PRD): SLC47A2 mRNA
Genes: SLC47A2; MATE2
Study NCT05741372 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study NCT05741372 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study NCT05741372 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT06372470 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05365581 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT06233903 — Predictive Biomarker (PRD): NE
Study NCT06274515 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06274515 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06274515 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06274515 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06274515 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06061770 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06640413 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT06640413 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05411887 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05411887 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05958849 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04786444 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04762680 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06357039 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study NCT04980833 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT06345027 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT05616650 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05815524 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06503276 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT06503276 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT06683469 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT05107193 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study NCT05761301 — Predictive Biomarker (PRD): KHK mRNA
Genes: KHK
Study NCT05429502 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT05537948 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT06469216 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05314439 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study NCT05879926 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05879926 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04826354 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04826354 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05538624 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05583721 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05027867 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2