TrialPanorama/TrialPanorama-database huggingface dataset:
Study 36177001 — Predictive Biomarker (PRD): CD300LG mRNA
Genes: CD300LG; CLM9; TREM4; UNQ422/PRO846
Study 36177001 — Predictive Biomarker (PRD): CD96 mRNA
Genes: CD96
Study 36177001 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Protein S100-P
Genes: S100P; S100E
Study 34780798 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 34415830 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 37728446 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32918971 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32389383 — Surrogate Endpoint (SUR): Blood pressure
Study 32445184 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32356332 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33514270 — Predictive Biomarker (PRD): TUSC3 mRNA
Genes: TUSC3; N33
Study 32455866 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 33166056 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 33982068 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 34315522 — Surrogate Endpoint (SUR): Blood pressure
Study 36163905 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 36163905 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 32797125 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 32797125 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Sclerostin
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study 32797125 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 32105267 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 33303553 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 33459776 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33459776 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32323103 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32323103 — Predictive Biomarker (PRD): GP2 mRNA
Genes: GP2
Study 32323103 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33420583 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34475231 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33737455 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34969035 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33293549 — Surrogate Endpoint (SUR): Blood pressure
Study 34531823 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 36482620 — Surrogate Endpoint (SUR): Blood pressure
Study 32028411 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 33524876 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33524876 — Safety Biomarker (SAF): IL-6 and IL-10
Study 32988721 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32067098 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 35576915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32302757 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 35354306 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 32862592 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32862592 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35180646 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33781141 — Predictive Biomarker (PRD): LPAR1 mRNA
Genes: LPAR1; EDG2; LPA1
Study 33781141 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32106642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34582449 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 36153583 — Surrogate Endpoint (SUR): Serum calcium
Study 36153583 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 33381795 — Surrogate Endpoint (SUR): Blood pressure
Study 33381795 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 34482412 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 32366244 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32452085 — Surrogate Endpoint (SUR): Blood pressure
Study 34159412 — Surrogate Endpoint (SUR): Blood pressure
Study 35765946 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35086141 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 35086141 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33190420 — Surrogate Endpoint (SUR): Blood pressure
Study 32176166 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33720089 — Monitoring Biomarker (MOI): HBV DNA
Study 36315917 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36315917 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 33858668 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 32481510 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 33333055 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 33333055 — Predictive Biomarker (PRD): Leucine-rich alpha-2-glycoprotein
Genes: LRG1; LRG
Study 32697889 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 35908849 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 35753247 — Surrogate Endpoint (SUR): Blood pressure
Study 34171465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32062371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32062371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32062371 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 32584367 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34836179 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 33418429 — Surrogate Endpoint (SUR): Blood pressure
Study 32354366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36030888 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 33145643 — Surrogate Endpoint (SUR): Blood pressure
Study 33145643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36152382 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 33099812 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35057420 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33506054 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 33506054 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 33506054 — Predictive Biomarker (PRD): BPIFA1 mRNA
Genes: BPIFA1; LUNX; NASG; PLUNC; SPLUNC1; SPURT; UNQ787/PRO1606
Study 33506054 — Predictive Biomarker (PRD): BPIFB1 mRNA
Genes: BPIFB1; C20orf114; LPLUNC1; UNQ706/PRO1357
Study 33506054 — Predictive Biomarker (PRD): BPIFB2 mRNA
Genes: BPIFB2; BPIL1; C20orf184; LPLUNC2; UNQ2489/PRO5776
Study 33506054 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 33506054 — Predictive Biomarker (PRD): LYZ mRNA
Genes: LYZ; LZM
Study 33506054 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study 33506054 — Predictive Biomarker (PRD): Calgranulin B
Genes: S100A9; CAGB; CFAG; MRP14
Study 33506054 — Predictive Biomarker (PRD): H2BC10 mRNA
Genes: H2BC4; H2BFL; HIST1H2BC;; H2BC6; H2BFH; HIST1H2BE;; H2BC7; H2BFG; HIST1H2BF;; H2BC8; H2BFA; HIST1H2BG;; H2BC10; H2BFK; HIST1H2BI
Study 32705177 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 35139273 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 34617567 — Safety Biomarker (SAF): Interleukin 1
Study 34617567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34375712 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 36199177 — Surrogate Endpoint (SUR): Blood pressure
Study 34116144 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 36372355 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 35606099 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34302571 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33545781 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36163903 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 36163903 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 34521461 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35687604 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32808239 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32808239 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33668309 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 33668309 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 33668309 — Surrogate Endpoint (SUR): Serum triglycerides
Study 33274466 — Predictive Biomarker (PRD): AQP1 mRNA
Genes: AQP1; CHIP28
Study 33274466 — Safety Biomarker (SAF): Reactive oxygen species
Study 33274466 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 34843657 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 33712909 — Safety Biomarker (SAF): IL-6 and IL-10
Study 33949052 — Predictive Biomarker (PRD): FURIN mRNA
Genes: FURIN; FUR; PACE; PCSK3
Study 36357459 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34154321 — Surrogate Endpoint (SUR): Bone mineral density
Study 33653118 — Predictive Biomarker (PRD): KCNQ2 mRNA
Genes: KCNQ2
Study 33689525 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33689525 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33689525 — Surrogate Endpoint (SUR): Blood pressure
Study 33073938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33073938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32878112 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32386001 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34383143 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32967799 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 34409637 — Predictive Biomarker (PRD): NT5E mRNA
Genes: NT5E; NT5; NTE
Study 34409637 — Predictive Biomarker (PRD): GLDC mRNA
Genes: GLDC; GCSP
Study 34409637 — Predictive Biomarker (PRD): NUDT17 mRNA
Genes: NUDT17
Study 34409637 — Predictive Biomarker (PRD): MSH4 mRNA
Genes: MSH4
Study 34409637 — Predictive Biomarker (PRD): PTER mRNA
Genes: PTER
Study 34409637 — Predictive Biomarker (PRD): SERPINB6 mRNA
Genes: SERPINB6; PI6; PTI
Study 32513294 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 33812699 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 33812699 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 33812699 — Predictive Biomarker (PRD): SLC22A1 mRNA
Genes: SLC22A1; OCT1
Study 33812699 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 33812699 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 33812699 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 36198259 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32466773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33536010 — Safety Biomarker (SAF): Hyaluronic acid
Study 34472504 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 34472504 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 33070154 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 35752551 — Safety Biomarker (SAF): Hyaluronic acid
Study 35126199 — Safety Biomarker (SAF): BDNF
Study 33727659 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33727659 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32419549 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 32419549 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 32419549 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33710344 — Predictive Biomarker (PRD): IL1R1 mRNA
Genes: IL1R1; IL1R; IL1RA; IL1RT1
Study 33710344 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 32606097 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33802559 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 33067279 — Safety Biomarker (SAF): BDNF
Study 35192016 — Surrogate Endpoint (SUR): Serum sodium
Study 34776140 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 35579951 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35579951 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33675447 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33675447 — Surrogate Endpoint (SUR): Blood pressure
Study 33290971 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33290971 — Surrogate Endpoint (SUR): Blood pressure
Study 32529506 — Surrogate Endpoint (SUR): Blood pressure
Study 34709363 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34709363 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34969074 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 35365148 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 35610083 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35610083 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32046467 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 35909384 — Surrogate Endpoint (SUR): Blood pressure
Study 33222598 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34888612 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33638625 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 35793110 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34526104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34526104 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 32998940 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 32998940 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 32998940 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 32998940 — Predictive Biomarker (PRD): Hormone receptor
Study 32998940 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34450192 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32804345 — Surrogate Endpoint (SUR): Blood pressure
Study 32644829 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32644829 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32644829 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33188651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33188651 — Safety Biomarker (SAF): IL-6 and IL-10
Study 33236509 — Surrogate Endpoint (SUR): Serum creatinine
Study 33236509 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 33236509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32604288 — Surrogate Endpoint (SUR): Blood pressure
Study 616497285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32348985 — Surrogate Endpoint (SUR): Serum creatinine
Study 32348985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33880021 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33880021 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35134817 — Surrogate Endpoint (SUR): Blood pressure
Study 35075138 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35075138 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 35075138 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 35110894 — Surrogate Endpoint (SUR): Blood pressure
Study 35341689 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32492138 — Surrogate Endpoint (SUR): Blood pressure
Study 35334836 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 32673309 — Surrogate Endpoint (SUR): Blood pressure
Study 33646464 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32134035 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 35623869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35623869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33822328 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 33850272 — Surrogate Endpoint (SUR): Blood pressure
Study 34787298 — Surrogate Endpoint (SUR): Blood pressure
Study 34117621 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32770972 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32770972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32770972 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33752070 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33752070 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 33752070 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 33752070 — Predictive Biomarker (PRD): GPX4 mRNA
Genes: GPX4
Study 32303198 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 33616345 — Safety Biomarker (SAF): Connecting peptide
Genes: AHSG; FETUA; PRO2743
Study 33616345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33616345 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33616345 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33616345 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32101256 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 32975061 — Safety Biomarker (SAF): Hyaluronic acid
Study 35188581 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35188581 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32147955 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 35227250 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 34464996 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 32393654 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33769656 — Surrogate Endpoint (SUR): Blood pressure
Study 32876488 — Predictive Biomarker (PRD): RETN mRNA
Genes: RETN; FIZZ3; HXCP1; RSTN; UNQ407/PRO1199
Study 32876488 — Predictive Biomarker (PRD): PTPRU mRNA
Genes: PTPRU; FMI; PCP2; PTPRO
Study 32876488 — Predictive Biomarker (PRD): STXBP2 mRNA
Genes: STXBP2; UNC18B
Study 32876488 — Predictive Biomarker (PRD): XAB2 mRNA
Genes: XAB2; HCNP; KIAA1177; SYF1; PP3898
Study 34174137 — Surrogate Endpoint (SUR): Blood pressure
Study 34146045 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33970955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34164944 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 35067488 — Surrogate Endpoint (SUR): Blood pressure
Study 32567372 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33378515 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 35760393 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 35760393 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 32357239 — Surrogate Endpoint (SUR): Blood pressure
Study 33507202 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 36370961 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 36370961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34684324 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 35208555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34362713 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 33562729 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33401235 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33401235 — Predictive Biomarker (PRD): Hormone receptor
Study 33106286 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 35953331 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 35953331 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 33181049 — Predictive Biomarker (PRD): CHIC1 mRNA
Genes: CHIC1; BRX
Study 34765049 — Predictive Biomarker (PRD): PLIN3 mRNA
Genes: PLIN3; M6PRBP1; TIP47
Study 34002559 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35001885 — Safety Biomarker (SAF): MTHFR