TrialPanorama/TrialPanorama-database huggingface dataset:
Study 37395974 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37395974 — Surrogate Endpoint (SUR): Blood pressure
Study 37396307 — Monitoring Biomarker (MOI): HBV DNA
Study 37396586 — Predictive Biomarker (PRD): IVL mRNA
Genes: IVL
Study 37396808 — Surrogate Endpoint (SUR): Forced vital capacity
Study 37397078 — Surrogate Endpoint (SUR): Blood pressure
Study 37397985 — Predictive Biomarker (PRD): ZNF335 mRNA
Genes: ZNF335
Study 37397985 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37398043 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 37398079 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 37398992 — Predictive Biomarker (PRD): YES1 mRNA
Genes: YES1; YES
Study 37398992 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 37398992 — Monitoring Biomarker (MOI): Cell-free DNA
Study 37399099 — Safety Biomarker (SAF): C-C motif chemokine 19
Genes: CCL19; ELC; MIP3B; SCYA19
Study 37399099 — Predictive Biomarker (PRD): CCL21 mRNA
Genes: CCL21; SCYA21; UNQ784/PRO1600
Study 37399355 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 37399355 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 37399355 — Predictive Biomarker (PRD): CAMLG mRNA
Genes: CAMLG; CAML; GET2
Study 37399355 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 37399456 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 37400162 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 37400771 — Predictive Biomarker (PRD): NOTUM mRNA
Genes: NOTUM; OK/SW-CL.30
Study 37400771 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 37400844 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 37400844 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 37401523 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37401523 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 37401523 — Surrogate Endpoint (SUR): Blood pressure
Study 37401618 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 37401774 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37402092 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study 37402144 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 37402153 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 37402471 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37402471 — Predictive Biomarker (PRD): Hormone receptor
Study 37403057 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 37403410 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 37404160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37405504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37405822 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 37406106 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37406106 — Predictive Biomarker (PRD): MT1H mRNA
Genes: MT1H
Study 37406106 — Predictive Biomarker (PRD): MT1E mRNA
Genes: MT1E
Study 37406106 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 37406106 — Predictive Biomarker (PRD): MSMB mRNA
Genes: MSMB; PRSP
Study 37406106 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 37406106 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 37406106 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 37406251 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 37406350 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37406760 — Surrogate Endpoint (SUR): Blood pressure
Study 37406777 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 37407001 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 37407001 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 37407040 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 37407058 — Predictive Biomarker (PRD): SLC40A1 mRNA
Genes: SLC40A1; FPN; FPN1; IREG1; SLC11A3; MSTP079
Study 37407113 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 37407142 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 37407154 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 37407326 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 37407950 — Predictive Biomarker (PRD): Hormone receptor
Study 37407989 — Surrogate Endpoint (SUR): Blood pressure
Study 37408044 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 37408044 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 37408044 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 37408044 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 37408044 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 37408044 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 37408044 — Predictive Biomarker (PRD): CXCL2 mRNA
Genes: CXCL2; GRO2; GROB; MIP2A; SCYB2
Study 37408044 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 37409229 — Predictive Biomarker (PRD): CXCR1 mRNA
Genes: CXCR1; CMKAR1; IL8RA
Study 37409229 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 37409229 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 37409229 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 37409270 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 37409565 — Surrogate Endpoint (SUR): Pathological complete response
Study 37409613 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37409757 — Safety Biomarker (SAF): MTHFR
Study 37409780 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 37409892 — Monitoring Biomarker (MOI): Cell-free DNA
Study 37410476 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 37410699 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 37411039 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 37414012 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 37414060 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 37414060 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 37414062 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 37414137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37414215 — Surrogate Endpoint (SUR): Pathological complete response
Study 37414422 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 37414705 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 37414923 — Surrogate Endpoint (SUR): Blood pressure
Study 37415001 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 37415001 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 37415239 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37415239 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37415246 — Surrogate Endpoint (SUR): Bone mineral density
Study 37415381 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 37416926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37417650 — Predictive Biomarker (PRD): PRRC2A mRNA
Genes: PRRC2A; BAT2; G2
Study 37417725 — Surrogate Endpoint (SUR): Bone mineral density
Study 37417824 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 37417948 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 37417970 — Safety Biomarker (SAF): Hyaluronic acid
Study 37418263 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37418304 — Surrogate Endpoint (SUR): Blood pressure
Study 37418643 — Predictive Biomarker (PRD): EYS mRNA
Genes: EYS; C6orf178; C6orf179; C6orf180; EGFL10; EGFL11; SPAM; UNQ9424/PRO34591
Study 37419394 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 37419969 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 37420006 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 37420006 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 37420006 — Safety Biomarker (SAF): Interleukin 1
Study 37420274 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37420274 — Predictive Biomarker (PRD): Hormone receptor
Study 37421291 — Surrogate Endpoint (SUR): Serum creatinine
Study 37421604 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 37421604 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 37422688 — Predictive Biomarker (PRD): NEDD8 mRNA
Genes: NEDD8
Study 37422688 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 37422688 — Predictive Biomarker (PRD): MECOM mRNA
Genes: MECOM; EVI1; MDS1; PRDM3
Study 37422688 — Predictive Biomarker (PRD): PMAIP1 mRNA
Genes: PMAIP1; NOXA
Study 37422688 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 37422772 — Predictive Biomarker (PRD): AKR1C3 mRNA
Genes: AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
Study 37423231 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 37423801 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37423882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37424311 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 37424386 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 37424386 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study 37424386 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 37424386 — Predictive Biomarker (PRD): CCND2 mRNA
Genes: CCND2
Study 37424386 — Predictive Biomarker (PRD): CCND3 mRNA
Genes: CCND3
Study 37424386 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 37425372 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 37425721 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 37426179 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 37426430 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 37426430 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37426947 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37427145 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 37427145 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 37428195 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study 37428273 — Predictive Biomarker (PRD): SMAD4 mRNA
Genes: SMAD4; DPC4; MADH4
Study 37428347 — Predictive Biomarker (PRD): Hormone receptor
Study 37428653 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 37429637 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 37429637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37429923 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 37430233 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 37430359 — Surrogate Endpoint (SUR): Serum creatinine
Study 37430546 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37431558 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 37431838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37431838 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 37432736 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37432736 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 37432736 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 37432736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37432736 — Predictive Biomarker (PRD): KLRG1 mRNA
Genes: KLRG1; CLEC15A; MAFA; MAFAL
Study 37432736 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 37432736 — Predictive Biomarker (PRD): EOMES mRNA
Genes: EOMES; TBR2
Study 37433173 — Surrogate Endpoint (SUR): Blood pressure
Study 37433173 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 37433436 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 37433436 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 37433436 — Surrogate Endpoint (SUR): Blood pressure
Study 37433698 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37433698 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 37433698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37433734 — Predictive Biomarker (PRD): TKTL1 mRNA
Genes: TKTL1; TKR; TKT2
Study 37433788 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 37434027 — Surrogate Endpoint (SUR): Serum creatinine
Study 37434027 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 37434165 — Predictive Biomarker (PRD): SP4 mRNA
Genes: SP4
Study 37434306 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37434306 — Predictive Biomarker (PRD): Hormone receptor
Study 37435073 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37435938 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 37437694 — Surrogate Endpoint (SUR): Blood pressure
Study 37438071 — Predictive Biomarker (PRD): SPDEF mRNA
Genes: SPDEF; PDEF; PSE
Study 37438197 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 37438722 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 37438734 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 37438734 — Surrogate Endpoint (SUR): Serum creatinine
Study 37438741 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 37438853 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 37438853 — Pharmacodynamic Biomarker (PDY): GATA-type zinc finger protein 1
Genes: ZGLP1; GLP1
Study 37438853 — Surrogate Endpoint (SUR): Blood pressure
Study 37439373 — Predictive Biomarker (PRD): MBTPS1 mRNA
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 37439373 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 37439701 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 37440099 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 37440099 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study 37440217 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 37440239 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37440239 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 37440239 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 37441104 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 37441104 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study 37441546 — Safety Biomarker (SAF): Hyaluronic acid
Study 37442152 — Monitoring Biomarker (MOI): HBV DNA
Study 37442748 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 37442917 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37442917 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 37443083 — Surrogate Endpoint (SUR): Serum creatinine
Study 37443452 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 37443809 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37444406 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 37444551 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 37449424 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37449424 — Surrogate Endpoint (SUR): Blood pressure
Study 37449568 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 37449573 — Surrogate Endpoint (SUR): Blood pressure
Study 37449658 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 37449716 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 37450351 — Predictive Biomarker (PRD): DIABLO mRNA
Genes: DIABLO; SMAC
Study 37450351 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37450351 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 37450351 — Predictive Biomarker (PRD): Hormone receptor
Study 37450351 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 37451295 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 37451297 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37451695 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 37451877 — Predictive Biomarker (PRD): TMPRSS11D mRNA
Genes: TMPRSS11D; HAT
Study 37451930 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37451930 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 37452151 — Surrogate Endpoint (SUR): Bone mineral density
Study 37452174 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37452279 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 37452341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 37452374 — Monitoring Biomarker (MOI): Cell-free DNA
Study 37452707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37452707 — Safety Biomarker (SAF): Interleukin 1
Study 37452707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37452849 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37453736 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 37453737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37454014 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 37455345 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 37455345 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 37455345 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 37455345 — Predictive Biomarker (PRD): PTPN11 mRNA
Genes: PTPN11; PTP2C; SHPTP2
Study 37455345 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 37455588 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study 37456358 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 37456507 — Surrogate Endpoint (SUR): Bone mineral density
Study 37457622 — Surrogate Endpoint (SUR): Serum creatinine
Study 37457966 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 37458272 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 37458583 — Monitoring Biomarker (MOI): HBV DNA
Study 37459141 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 37459153 — Surrogate Endpoint (SUR): Blood pressure
Study 37459248 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 37459335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37459335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37459335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37460024 — Predictive Biomarker (PRD): SLC5A8 mRNA
Genes: SLC5A8; AIT; SMCT; SMCT1
Study 37460603 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study 37460683 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 37460683 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 37460683 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 37460683 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 37460782 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 37461034 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 37461089 — Surrogate Endpoint (SUR): Blood pressure
Study 37461207 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37461659 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 37461954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 37461987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37462430 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 37462430 — Surrogate Endpoint (SUR): Blood pressure
Study 37462430 — Surrogate Endpoint (SUR): Pulmonary vascular resistance