TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04991077 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04910360 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT05267327 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT06458036 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT05306041 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT05306041 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05306041 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05306041 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT06375213 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06315556 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06315556 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06455735 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05003479 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04954001 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT04954001 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT04684459 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05397535 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04999436 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study NCT04917523 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04917523 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05977959 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05880264 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05440916 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06236555 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT06429644 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT05667220 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT06316076 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06579222 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04592770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04592770 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04592770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04592770 — Safety Biomarker (SAF): BDNF
Study NCT04958499 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04958499 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05880966 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05839392 — Predictive Biomarker (PRD): MECOM mRNA
Genes: MECOM; EVI1; MDS1; PRDM3
Study NCT05026060 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT05922384 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study NCT05922384 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04989959 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT05253495 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT04879121 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT05534919 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT05534919 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05238025 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06557148 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT00546026 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05870748 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT06186427 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT06529055 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06117280 — Predictive Biomarker (PRD): PXN mRNA
Genes: PXN
Study NCT04728347 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06519344 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT06519344 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT05147831 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04895423 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study NCT04895423 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT05756777 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05756777 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT05756777 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT04950244 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT06377267 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06377267 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05724407 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05724407 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05448963 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06062810 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06628193 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06723925 — Predictive Biomarker (PRD): BTD mRNA
Genes: BTD
Study NCT05063357 — Predictive Biomarker (PRD): CD276 mRNA
Genes: CD276; B7H3; PSEC0249; UNQ309/PRO352
Study NCT05145140 — Safety Biomarker (SAF): Urinary microalbumin
Study NCT06729463 — Predictive Biomarker (PRD): IKBKB mRNA
Genes: IKBKB; IKKB
Study NCT05664893 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05799651 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05302492 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04656535 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study NCT01437280 — Predictive Biomarker (PRD): MBOAT4 mRNA
Genes: MBOAT4; GOAT; OACT4; FKSG89
Study NCT01437280 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05283148 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06213259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04746053 — Predictive Biomarker (PRD): HNF1B mRNA
Genes: HNF1B; TCF2
Study NCT04746053 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00561366 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04808817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04808817 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study NCT04808817 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT04808817 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study NCT05074927 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04620304 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05836649 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT06522373 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT05635201 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06212297 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study NCT06040905 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06040905 — Safety Biomarker (SAF): BDNF
Study NCT05332171 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05889715 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04781400 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05754853 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06172387 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT06010329 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06462053 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05651100 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05651100 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT04250454 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT06127407 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT04924608 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT06012227 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT06528951 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05506774 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT04860297 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04738981 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT06132438 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT05838365 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT05925127 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05881252 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05788484 — Predictive Biomarker (PRD): LILRB2 mRNA
Genes: LILRB2; ILT4; LIR2; MIR10
Study NCT04830813 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06604689 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06598202 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT06019182 — Predictive Biomarker (PRD): EIF2S3 mRNA
Genes: EIF2S3; EIF2G
Study NCT05576155 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06452498 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06668714 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT06665334 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT06047626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04732598 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04732598 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04732598 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04882072 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT05881538 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06144749 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT00000747 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06122961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04668157 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06445959 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT06059638 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06607978 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06539624 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT05258110 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05372614 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05017116 — Monitoring Biomarker (MOI): HBV DNA
Study NCT05846659 — Predictive Biomarker (PRD): STING1 mRNA
Genes: STING1; ERIS; MITA; STING; TMEM173
Study NCT06682741 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06682741 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study NCT06682741 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study NCT06682884 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06433947 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study NCT06090227 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT06235086 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05470647 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT05470647 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT04683068 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04683068 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT06126003 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04232033 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT05786469 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05786469 — Surrogate Endpoint (SUR): Serum potassium
Study NCT05339217 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05581056 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT06556615 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study NCT01130259 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01130259 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT05223530 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05718856 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT04847206 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06559033 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study NCT04989946 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT06327581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06327581 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06327581 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT06327581 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06348797 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study NCT06078904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06059495 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT06451419 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study NCT05310227 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study NCT05940376 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT05940376 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05180695 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT05180695 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT05143229 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06251362 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06251362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06251362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06251362 — Safety Biomarker (SAF): BDNF
Study NCT06007768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06007768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06007768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06007768 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT00698373 — Predictive Biomarker (PRD): SLC7A5 mRNA
Genes: SLC7A5; CD98LC; LAT1; MPE16
Study NCT06270706 — Predictive Biomarker (PRD): PLN mRNA
Genes: PLN; PLB
Study NCT04738292 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04738292 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05421351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06077773 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study NCT05129228 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): VGF mRNA
Genes: VGF
Study NCT05932277 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT05932277 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT05932277 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05932277 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT05932277 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT05429905 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT05429905 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06724809 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT06724809 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT06724809 — Predictive Biomarker (PRD): Anti-aquaporin-4 antibody
Study NCT06724809 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT06724692 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT06074029 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06169410 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT05151458 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT06101381 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05596695 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04462328 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04544592 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04677179 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT05691530 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05225194 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06060015 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05866757 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT05977036 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05977036 — Predictive Biomarker (PRD): TK1 mRNA
Genes: TK1
Study NCT05977036 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06176807 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05693701 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT06598449 — Predictive Biomarker (PRD): SCN1A mRNA
Genes: SCN1A; NAC1; SCN1
Study NCT05717439 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT06238882 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06238882 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06238882 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT05252507 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06287840 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06533826 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05676853 — Safety Biomarker (SAF): Arginase-1
Genes: ARG1
Study NCT03866499 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04898946 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06063018 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04661800 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT05777226 — Predictive Biomarker (PRD): SORD mRNA
Genes: SORD
Study NCT04859608 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT04843098 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT06510894 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study NCT06020898 — Safety Biomarker (SAF): CD177 antigen
Genes: CD177; NB1; PRV1; UNQ595/PRO1181
Study NCT05847959 — Predictive Biomarker (PRD): XK mRNA
Genes: XK; XKR1; XRG1
Study NCT06408103 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT05904730 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05475366 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study NCT05626751 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05375994 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04850495 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT06247280 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00000689 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00000689 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04881916 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04428372 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06259760 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05385432 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05929209 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT05355064 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT05355064 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT05827861 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05827861 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06610006 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05248685 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT06024239 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT05952687 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT05199051 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05632094 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06610721 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT06610721 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2