TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT06606613 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06612554 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06439199 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT06439199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06439199 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT06297525 — Predictive Biomarker (PRD): CTPS1 mRNA
Genes: CTPS1; CTPS
Study NCT06297525 — Predictive Biomarker (PRD): CTPS2 mRNA
Genes: CTPS2
Study NCT06071195 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05899920 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05677594 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT06520956 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04987073 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study NCT06604104 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05239533 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT06221969 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT04923126 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT05081336 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06693739 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06696820 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT06696833 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05759572 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05759572 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05759572 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06326034 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05507034 — Safety Biomarker (SAF): BDNF
Study NCT06696378 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06696378 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT06711887 — Surrogate Endpoint (SUR): Complete renal response
Study NCT05450484 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05606679 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study NCT06208735 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT06712173 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study NCT04389580 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04389580 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT06617390 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT04286555 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06238466 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06508099 — Surrogate Endpoint (SUR): Hematologic response
Study NCT05287503 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study NCT05287503 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT04483531 — Predictive Biomarker (PRD): ATP8B1 mRNA
Genes: ATP8B1; ATPIC; FIC1; PFIC
Study NCT05654038 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06239714 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT06368752 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT04880382 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05982249 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05871333 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05871333 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06759038 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05377736 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04845646 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04845646 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT04845646 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT06582056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05553834 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT05382156 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT06147271 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06147271 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05192512 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study NCT04831138 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT06130787 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT06130787 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT06043622 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04732845 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06308133 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05118360 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06557278 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04813562 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05626283 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study NCT04836520 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04836520 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04836520 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05445609 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study NCT05158569 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06616870 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study NCT06616870 — Predictive Biomarker (PRD): SMAD3 mRNA
Genes: SMAD3; MADH3
Study NCT06616870 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study NCT06680817 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06083636 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT00173030 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00173030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06084741 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT05208879 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study NCT05208879 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05310721 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06759662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06759662 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06759662 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT06758882 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06759181 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04817072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06259279 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06393660 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT06094998 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06094998 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study NCT06094998 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT05119933 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05666518 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT05666518 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04646187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06546007 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05190185 — Predictive Biomarker (PRD): CD276 mRNA
Genes: CD276; B7H3; PSEC0249; UNQ309/PRO352
Study NCT05599633 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05599633 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05328856 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04847648 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT06360757 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06061705 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06061705 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study NCT06061705 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study NCT06061705 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05270928 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06248086 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06630806 — Predictive Biomarker (PRD): GPRC5D mRNA
Genes: GPRC5D
Study NCT04829019 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05558761 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06357923 — Predictive Biomarker (PRD): LAMP2 mRNA
Genes: LAMP2
Study NCT04826003 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT04826003 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT05889975 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study NCT01947608 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03911336 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04831710 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04831710 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04621071 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04692181 — Predictive Biomarker (PRD): SYNM mRNA
Genes: SYNM; DMN; KIAA0353; SYN
Study NCT06153160 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05596409 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05596409 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05596409 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study NCT05596409 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05596409 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04973774 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study NCT05542316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06468306 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study NCT06468306 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06468306 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study NCT06468306 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study NCT06468306 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT06468306 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study NCT06468306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06468306 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study NCT06468306 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06070012 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT06070012 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06683573 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05328908 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study NCT05328908 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT05328908 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05073250 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT05219383 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study NCT04500548 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study NCT05620524 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study NCT05348252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT06758570 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05054257 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05728476 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05728476 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06103279 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05327452 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06004245 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04858321 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05830799 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT05830799 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT05830799 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05896969 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05578092 — Predictive Biomarker (PRD): SOS1 mRNA
Genes: SOS1
Study NCT05578092 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05793411 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study NCT04720391 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study NCT04720391 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT05640687 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05730712 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05664217 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04296942 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04296942 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04296942 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04162353 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04162353 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06450639 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06450639 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study NCT06450639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05363228 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05363228 — Safety Biomarker (SAF): BDNF
Study NCT06247501 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04975893 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05414864 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05837195 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study NCT06118619 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT04410575 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT06663163 — Predictive Biomarker (PRD): Cyclin-dependent kinase-like 5
Genes: CDKL5; STK9
Study NCT06617130 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study NCT06617052 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT06227117 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06227117 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06297655 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT05294952 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study NCT05548569 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04893564 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study NCT04893564 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT04893564 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04893564 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04893564 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT04893564 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT04893564 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study NCT04893564 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06755684 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06751589 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT06751589 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06759636 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study NCT05168969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CTNNB1 mRNA
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study NCT06759714 — Predictive Biomarker (PRD): UPK1A mRNA
Genes: UPK1A; TSPAN21
Study NCT06759714 — Predictive Biomarker (PRD): UNC5B mRNA
Genes: UNC5B; P53RDL1; UNC5H2; UNQ1883/PRO4326
Study NCT06760364 — Predictive Biomarker (PRD): MSLN mRNA
Genes: MSLN; MPF
Study NCT06758700 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT05850520 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05850520 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05755087 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT04780581 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05728502 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04958265 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT05852691 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06334419 — Predictive Biomarker (PRD): FMR1
Genes: FMRP; FRAXA; MGC87458
Study NCT06641908 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT04234022 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study NCT05203055 — Monitoring Biomarker (MOI): HBV DNA
Study NCT05016934 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06369649 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04782128 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06555393 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04703621 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT05420779 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06503107 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05178576 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05813379 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT06290219 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06061783 — Surrogate Endpoint (SUR): Serum sodium
Study NCT02028975 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT05576623 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06169449 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05273931 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06410157 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study NCT05281926 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT05409365 — Predictive Biomarker (PRD): SERPINB4 mRNA
Genes: SERPINB4; PI11; SCCA2
Study NCT05390580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05390580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05390580 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05390580 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT06365671 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06759545 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06759740 — Predictive Biomarker (PRD): GLP1R mRNA
Genes: GLP1R
Study NCT06759363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06759363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06759363 — Safety Biomarker (SAF): Interleukin 1
Study NCT06759363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06759363 — Safety Biomarker (SAF): miR-192
Genes: MIR192
Study NCT06759363 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study NCT06759597 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05877027 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05463263 — Predictive Biomarker (PRD): CTPS1 mRNA
Genes: CTPS1; CTPS
Study NCT04462302 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study NCT04689347 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT06008249 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT05394766 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04877288 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study NCT05196516 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study NCT06355479 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT06250751 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT06317025 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05625204 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05625204 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF