TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33560891 — Surrogate Endpoint (SUR): Blood pressure
Study 34459400 — Predictive Biomarker (PRD): DNER mRNA
Genes: DNER; BET; UNQ262/PRO299
Study 32619792 — Surrogate Endpoint (SUR): Blood pressure
Study 34748169 — Surrogate Endpoint (SUR): Serum calcium
Study 32885808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32885808 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35090047 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33577375 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 32084431 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 32084431 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 32084431 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 32379635 — Surrogate Endpoint (SUR): Blood pressure
Study 34324430 — Surrogate Endpoint (SUR): Bone mineral density
Study 35176141 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 32952009 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32952009 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32952009 — Surrogate Endpoint (SUR): Blood pressure
Study 34229554 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35240966 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32156204 — Surrogate Endpoint (SUR): Blood pressure
Study 35908682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32145440 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 32552264 — Surrogate Endpoint (SUR): Blood pressure
Study 33960201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33960201 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33960201 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32317229 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32317229 — Safety Biomarker (SAF): Hyaluronic acid
Study 35235859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35537502 — Predictive Biomarker (PRD): CST1 mRNA
Genes: CST1
Study 35537502 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 32975739 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32975739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35804451 — Surrogate Endpoint (SUR): Blood pressure
Study 35804451 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33827495 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 32310850 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 34254405 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 34762373 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34762373 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 34762373 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34762373 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 36333364 — Safety Biomarker (SAF): Hyaluronic acid
Study 32996349 — Surrogate Endpoint (SUR): Blood pressure
Study 32996349 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35635717 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 32193541 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 32358566 — Predictive Biomarker (PRD): U2AF1 mRNA
Genes: U2AF1; U2AF35; U2AFBP; FP793
Study 35169373 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36027443 — Surrogate Endpoint (SUR): Blood pressure
Study 32572802 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 32572802 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32572802 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 36456992 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 35471613 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 36451459 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 36451459 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36451459 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35690515 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 34986284 — Surrogate Endpoint (SUR): Hematologic response
Study 34554372 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 34607574 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35366811 — Surrogate Endpoint (SUR): Blood pressure
Study 32556293 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35428889 — Surrogate Endpoint (SUR): Bone mineral density
Study 35013427 — Predictive Biomarker (PRD): ISG15 mRNA
Genes: ISG15; G1P2; UCRP
Study 35013427 — Predictive Biomarker (PRD): XAF1 mRNA
Genes: XAF1; BIRC4BP; XIAPAF1
Study 35013427 — Predictive Biomarker (PRD): TRIM25 mRNA
Genes: TRIM25; EFP; RNF147; ZNF147
Study 35013427 — Predictive Biomarker (PRD): USP18 mRNA
Genes: USP18; ISG43
Study 33547855 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 33211870 — Surrogate Endpoint (SUR): Bone mineral density
Study 35575618 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33665769 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33665769 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33665769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33665769 — Safety Biomarker (SAF): BDNF
Study 33665769 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35778856 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35778856 — Surrogate Endpoint (SUR): Blood pressure
Study 32484629 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 615918191 — Predictive Biomarker (PRD): PCLO mRNA
Genes: PCLO; ACZ; KIAA0559
Study 615918191 — Predictive Biomarker (PRD): GMCL2 mRNA
Genes: GMCL2; GCL; GMCL1L; GMCL1P1
Study 33358456 — Predictive Biomarker (PRD): TTMP mRNA
Genes: TTMP; C3orf52
Study 32374188 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 32374188 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32374188 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32374188 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35280833 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 33874683 — Surrogate Endpoint (SUR): Blood pressure
Study 33874683 — Surrogate Endpoint (SUR): Serum creatinine
Study 32505193 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32544846 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32487944 — Surrogate Endpoint (SUR): Blood pressure
Study 32989958 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 34734811 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 33728932 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32703188 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32122870 — Surrogate Endpoint (SUR): Serum creatinine
Study 33442660 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33442660 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33442660 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 32270440 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 35782072 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 35782072 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 35782072 — Predictive Biomarker (PRD): S100A2 mRNA
Genes: S100A2; S100L
Study 34152584 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 34152584 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 33028147 — Predictive Biomarker (PRD): ABCC8 mRNA
Genes: ABCC8; HRINS; SUR; SUR1
Study 33028147 — Predictive Biomarker (PRD): TRPM4 mRNA
Genes: TRPM4; LTRPC4
Study 34555204 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 36434858 — Surrogate Endpoint (SUR): Blood pressure
Study 35098531 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 35098531 — Surrogate Endpoint (SUR): Blood pressure
Study 33415870 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 36235821 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 32546652 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 36342940 — Surrogate Endpoint (SUR): Blood pressure
Study 32861806 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32861806 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 36096203 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 32293914 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 34268601 — Predictive Biomarker (PRD): WNT4 mRNA
Genes: WNT4; UNQ426/PRO864
Study 34935724 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 36196601 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36429807 — Surrogate Endpoint (SUR): Blood pressure
Study 34496087 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 36344766 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 32652024 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 35078831 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 34031695 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33262937 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32326727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32173648 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 36171562 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35147899 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 33596318 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35510322 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 35510322 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34960669 — Predictive Biomarker (PRD): TLR8 mRNA
Genes: TLR8; UNQ249/PRO286
Study 34960669 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 34960669 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 34960669 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 34271464 — Predictive Biomarker (PRD): LRIT1 mRNA
Genes: LRIT1; LRRC21; PAL
Study 32653532 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 34938354 — Surrogate Endpoint (SUR): Serum calcium
Study 35432844 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35432844 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32798568 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32798568 — Safety Biomarker (SAF): BDNF
Study 32798568 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 35240988 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 33504976 — Surrogate Endpoint (SUR): Blood pressure
Study 35643873 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 35643873 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 35047059 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34684116 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36592517 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 36592517 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 33772456 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33327237 — Surrogate Endpoint (SUR): Bone mineral density
Study 36094367 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 32835880 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 33906234 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34589541 — Predictive Biomarker (PRD): SLC4A7 mRNA
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 33750266 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 32290148 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 36309950 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 36309950 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 35597947 — Predictive Biomarker (PRD): LRRFIP1 mRNA
Genes: LRRFIP1; GCF2; TRIP
Study 32907635 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32583468 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32583468 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 35355249 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34428929 — Predictive Biomarker (PRD): BDKRB2 mRNA
Genes: BDKRB2; BKR2
Study 34428929 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34396911 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34396911 — Surrogate Endpoint (SUR): Serum creatinine
Study 32242018 — Predictive Biomarker (PRD): ADGRG1 mRNA
Genes: ADGRG1; GPR56; TM7LN4; TM7XN1; UNQ540/PRO1083
Study 35199834 — Predictive Biomarker (PRD): NFKBIA mRNA
Genes: NFKBIA; IKBA; MAD3; NFKBI
Study 35199834 — Predictive Biomarker (PRD): IL18BP mRNA
Genes: IL18BP
Study 35199834 — Pharmacodynamic Biomarker (PDY): Interleukin 7 receptor alpha
Genes: IL7R
Study 35199834 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 35199834 — Predictive Biomarker (PRD): NFKBIA
Genes: IKBA; MAD-3; IkappaBalpha
Study 32166837 — Surrogate Endpoint (SUR): Blood pressure
Study 34391301 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 35411924 — Surrogate Endpoint (SUR): Bone mineral density
Study 32975880 — Surrogate Endpoint (SUR): Blood pressure
Study 33099298 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 32681304 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 32201400 — Surrogate Endpoint (SUR): Blood pressure
Study 34651611 — Surrogate Endpoint (SUR): Blood pressure
Study 32762161 — Predictive Biomarker (PRD): FAH mRNA
Genes: FAH
Study 32762161 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35167999 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35167999 — Surrogate Endpoint (SUR): Blood pressure
Study 35167999 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33038062 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 33038062 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 33038062 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 34134579 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34134579 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 35415940 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 34253806 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 32191595 — Surrogate Endpoint (SUR): Blood pressure
Study 33752446 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33752446 — Safety Biomarker (SAF): BDNF
Study 32043907 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 32043907 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 35687705 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32125665 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 32125665 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 32125665 — Predictive Biomarker (PRD): CYP1A1 mRNA
Genes: CYP1A1
Study 32125665 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 35170528 — Monitoring Biomarker (MOI): HBV DNA
Study 33704808 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 33704808 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study 33704808 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 33509352 — Predictive Biomarker (PRD): GNL3 mRNA
Genes: GNL3; E2IG3; NS
Study 32326966 — Surrogate Endpoint (SUR): Blood pressure
Study 33094434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32600060 — Surrogate Endpoint (SUR): Serum creatinine
Study 34726144 — Predictive Biomarker (PRD): GDA mRNA
Genes: GDA; KIAA1258
Study 32324693 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33867254 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 33377898 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33377898 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35116567 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 33292046 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 33292046 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33292046 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 33126555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33126555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33126555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35807852 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35128402 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study 32033793 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32382551 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35583486 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 35583486 — Safety Biomarker (SAF): BDNF
Study 33455753 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 36404400 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 34328293 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 34328293 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 35096134 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35096134 — Surrogate Endpoint (SUR): Blood pressure
Study 32885389 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 32885389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32885389 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 35058800 — Predictive Biomarker (PRD): TMOD3 mRNA
Genes: TMOD3
Study 32805133 — Surrogate Endpoint (SUR): Blood pressure
Study 32192678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32448804 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35468658 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 35131740 — Predictive Biomarker (PRD): SIRPA mRNA
Genes: SIRPA; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP
Study 36286256 — Surrogate Endpoint (SUR): Blood pressure
Study 33097384 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 36280033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32481345 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 34625784 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 34964458 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 34292628 — Predictive Biomarker (PRD): OMG mRNA
Genes: OMG; OMGP
Study 32294244 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 32294244 — Surrogate Endpoint (SUR): Probing pocket depth
Study 35102948 — Surrogate Endpoint (SUR): Blood pressure
Study 33839207 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 36397422 — Predictive Biomarker (PRD): DTL mRNA
Genes: DTL; CDT2; CDW1; DCAF2; L2DTL; RAMP
Study 33609794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33609794 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 33175637 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 33175637 — Safety Biomarker (SAF): Preexisting antibody
Study 34452934 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 36169979 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 33785743 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34295782 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34103179 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 34103179 — Predictive Biomarker (PRD): RNASEH2B mRNA
Genes: RNASEH2B; DLEU8
Study 34103179 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 34103179 — Monitoring Biomarker (MOI): Cell-free DNA
Study 35143744 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN