TrialPanorama/TrialPanorama-database huggingface dataset:
Study 34412750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35088760 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 35088760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33359382 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33782365 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 35343321 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33712920 — Surrogate Endpoint (SUR): Bone mineral density
Study 32716114 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 36176963 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 32969202 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 33873267 — Surrogate Endpoint (SUR): Blood pressure
Study 32798787 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33040562 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33769952 — Surrogate Endpoint (SUR): Bone mineral density
Study 36445957 — Predictive Biomarker (PRD): CCN3 mRNA
Genes: CCN3; IGFBP9; NOV; NOVH
Study 36445957 — Predictive Biomarker (PRD): NOVA2 mRNA
Genes: NOVA2; ANOVA; NOVA3
Study 34340161 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 32448358 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32448358 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 36060146 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36060146 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36060146 — Surrogate Endpoint (SUR): Serum uric acid
Study 34816917 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34816917 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 33089427 — Predictive Biomarker (PRD): PTGDS mRNA
Genes: PTGDS; PDS
Study 34864768 — Safety Biomarker (SAF): BDNF
Study 33078636 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 35931991 — Surrogate Endpoint (SUR): Blood pressure
Study 35931991 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32641343 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 33320197 — Safety Biomarker (SAF): Hyaluronic acid
Study 34987480 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 34520831 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study 34520831 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 34520831 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 36109757 — Surrogate Endpoint (SUR): Blood pressure
Study 32521927 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 32521927 — Predictive Biomarker (PRD): HTATIP2 mRNA
Genes: HTATIP2; CC3; TIP30
Study 32521927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32521927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33811250 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33811250 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 33811250 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 32995976 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 32564438 — Surrogate Endpoint (SUR): Bone mineral density
Study 32578029 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 33486869 — Surrogate Endpoint (SUR): Blood pressure
Study 33486869 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 33486869 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33795330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32209983 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 33550228 — Surrogate Endpoint (SUR): Blood pressure
Study 33060632 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 32563496 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 33002791 — Surrogate Endpoint (SUR): Blood pressure
Study 33002791 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34836153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34836153 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34836153 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 33592176 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 33592176 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 33592176 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33000465 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 33402624 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 33002377 — Surrogate Endpoint (SUR): Blood pressure
Study 33002377 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 32053984 — Surrogate Endpoint (SUR): Blood pressure
Study 32050055 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 33227793 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 32888826 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 35029187 — Surrogate Endpoint (SUR): Blood pressure
Study 34440352 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34440352 — Predictive Biomarker (PRD): ACTN3 mRNA
Genes: ACTN3
Study 36207870 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 36207870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36207870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36207870 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32533883 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34758252 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32259228 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 32486256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34664527 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34664527 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 34950221 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34950221 — Monitoring Biomarker (MOI): miR-29a
Genes: MIR29A
Study 34950221 — Predictive Biomarker (PRD): miR-145
Genes: MIR145
Study 35951066 — Surrogate Endpoint (SUR): Blood pressure
Study 35285308 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35285308 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36322060 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 32080123 — Surrogate Endpoint (SUR): Blood pressure
Study 34143234 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 34143234 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32841251 — Surrogate Endpoint (SUR): Blood pressure
Study 35974352 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 33844642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35394961 — Predictive Biomarker (PRD): DDX53 mRNA
Genes: DDX53; CAGE
Study 32179874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33862045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32311911 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32311911 — Surrogate Endpoint (SUR): Blood pressure
Study 34776422 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 34666302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35356803 — Surrogate Endpoint (SUR): Serum uric acid
Study 33536398 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 33107490 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study 33107490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33107490 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 33107490 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 33107490 — Predictive Biomarker (PRD): Calgranulin B
Genes: S100A9; CAGB; CFAG; MRP14
Study 33107490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33641504 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 33641504 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 33947690 — Predictive Biomarker (PRD): SLFN11 mRNA
Genes: SLFN11
Study 32031665 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 32584996 — Surrogate Endpoint (SUR): Bone mineral density
Study 32314290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32314290 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 32314290 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32314290 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32314290 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32314290 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33566107 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 33006193 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 33006193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33006193 — Surrogate Endpoint (SUR): Blood pressure
Study 35316091 — Predictive Biomarker (PRD): DHH mRNA
Genes: DHH
Study 32678767 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 33051240 — Predictive Biomarker (PRD): ICOSLG mRNA
Genes: ICOSLG; B7H2; B7RP1; ICOSL; KIAA0653
Study 33051240 — Predictive Biomarker (PRD): ADAM10 mRNA
Genes: ADAM10; KUZ; MADM
Study 35756871 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 34843662 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32674250 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 32674250 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 34048528 — Surrogate Endpoint (SUR): Serum sodium
Study 35320813 — Predictive Biomarker (PRD): PDSS1 mRNA
Genes: PDSS1; DPS1; TPRT
Study 35320813 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 33471564 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33471564 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33471564 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33471564 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32557601 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 32557601 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 35351058 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 32854125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33019891 — Surrogate Endpoint (SUR): Bone mineral density
Study 34723864 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 32269278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35690073 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32170964 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 35279528 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35279528 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34812502 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 34904015 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 32838817 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 32149764 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 35295986 — Surrogate Endpoint (SUR): Blood pressure
Study 34898075 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33407619 — Monitoring Biomarker (MOI): HBV DNA
Study 32088676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32162503 — Surrogate Endpoint (SUR): Bone mineral density
Study 32814339 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35617770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35617770 — Surrogate Endpoint (SUR): Blood pressure
Study 35617770 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33152350 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 33152350 — Safety Biomarker (SAF): Reactive oxygen species
Study 34881935 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 35381657 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35381657 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32624366 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 32624366 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 34386735 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32595959 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 32595959 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 32758152 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 35088697 — Surrogate Endpoint (SUR): Blood pressure
Study 35523116 — Surrogate Endpoint (SUR): Bone mineral density
Study 34032127 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 32007650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34375388 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 34375388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34375388 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34710240 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32621657 — Safety Biomarker (SAF): Hyaluronic acid
Study 35938326 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35938326 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 33359375 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32048170 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 33502122 — Surrogate Endpoint (SUR): Blood pressure
Study 34784247 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 34784247 — Safety Biomarker (SAF): Reactive oxygen species
Study 35894657 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 32541643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32541643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36079758 — Surrogate Endpoint (SUR): Blood pressure
Study 32886181 — Safety Biomarker (SAF): Hyaluronic acid
Study 36083814 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 36083814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36048457 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 36048457 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 36048457 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 35973593 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34388698 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34388698 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 35837739 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 34839872 — Surrogate Endpoint (SUR): Blood pressure
Study 35990804 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 35990804 — Safety Biomarker (SAF): BDNF
Study 32324082 — Surrogate Endpoint (SUR): Blood pressure
Study 36501186 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 36501186 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33115894 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 35170144 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 35170144 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34391230 — Predictive Biomarker (PRD): CDCA7L mRNA
Genes: CDCA7L; HR1; JPO2; R1
Study 32903262 — Safety Biomarker (SAF): Reactive oxygen species
Study 32239322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32239322 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35894893 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 35411579 — Predictive Biomarker (PRD): TBP mRNA
Genes: TBP; GTF2D1; TF2D; TFIID
Study 35545724 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35545724 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 33872462 — Safety Biomarker (SAF): Hyaluronic acid
Study 32102680 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32102680 — Safety Biomarker (SAF): BDNF
Study 32986960 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35702841 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35702841 — Surrogate Endpoint (SUR): Blood pressure
Study 32061431 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33119861 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36286853 — Surrogate Endpoint (SUR): Blood pressure
Study 33949022 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 35718771 — Surrogate Endpoint (SUR): Blood pressure
Study 34702760 — Predictive Biomarker (PRD): IL37 mRNA
Genes: IL37; FIL1Z; IL1F7; IL1H4; IL1RP1
Study 32309918 — Predictive Biomarker (PRD): IGFBP2 mRNA
Genes: IGFBP2; BP2; IBP2
Study 33434615 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33256382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34374082 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 33374368 — Surrogate Endpoint (SUR): Blood pressure
Study 36068576 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 34444820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33069109 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 33136517 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32203978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34108261 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 34108261 — Predictive Biomarker (PRD): DUSP6 mRNA
Genes: DUSP6; MKP3; PYST1
Study 34108261 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 34108261 — Predictive Biomarker (PRD): HSPA6 mRNA
Genes: HSPA6; HSP70B'
Study 35572837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35572837 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 35572837 — Safety Biomarker (SAF): Interleukin 1
Study 35572837 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 35572837 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 32792244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33383371 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 33383371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33066009 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33066009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2