TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32097392 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 34903344 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 34098214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33310500 — Surrogate Endpoint (SUR): Blood pressure
Study 32306029 — Surrogate Endpoint (SUR): Blood pressure
Study 33951477 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35316820 — Safety Biomarker (SAF): Hyaluronic acid
Study 32589290 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 32589290 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 32589290 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 33610422 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 34402090 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34402090 — Safety Biomarker (SAF): BDNF
Study 36045021 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 32860696 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34162789 — Surrogate Endpoint (SUR): Blood pressure
Study 35720170 — Surrogate Endpoint (SUR): Blood pressure
Study 32763279 — Predictive Biomarker (PRD): CAPS2 mRNA
Genes: CAPS2; UG0636c06
Study 32763279 — Predictive Biomarker (PRD): TNFRSF25 mRNA
Genes: TNFRSF25; APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; UNQ455/PRO779
Study 32763279 — Predictive Biomarker (PRD): ZNF875 mRNA
Genes: ZNF875; HKR1
Study 34765324 — Surrogate Endpoint (SUR): Blood pressure
Study 32044511 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 32044511 — Surrogate Endpoint (SUR): Pathological complete response
Study 33389369 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33389369 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33351101 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 32706640 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 32706640 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 35751032 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 33332480 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 33332480 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 33370549 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 33370549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34708788 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33040814 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33040814 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 33040814 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 33040814 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 35212308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35212308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32899022 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 36319967 — Surrogate Endpoint (SUR): Serum potassium
Study 36319967 — Surrogate Endpoint (SUR): Serum sodium
Study 36319967 — Surrogate Endpoint (SUR): Serum calcium
Study 35192860 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 33925704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33925704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35956073 — Safety Biomarker (SAF): Hyaluronic acid
Study 32946039 — Surrogate Endpoint (SUR): Blood pressure
Study 33648515 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33648515 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 34718434 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 35688490 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 35688490 — Surrogate Endpoint (SUR): Blood pressure
Study 33472681 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33472681 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32507386 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 34145052 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36115179 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 33198809 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 33198809 — Safety Biomarker (SAF): Platelet to lymphocyte
Study 35120150 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 35819163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35819163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33768599 — Surrogate Endpoint (SUR): Blood pressure
Study 35564709 — Surrogate Endpoint (SUR): Blood pressure
Study 34528089 — Surrogate Endpoint (SUR): Serum creatinine
Study 33803802 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 34486480 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 33792961 — Safety Biomarker (SAF): Hyaluronic acid
Study 35387483 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 35387483 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 35387483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32879783 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 32879783 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32879783 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33518350 — Surrogate Endpoint (SUR): Bone mineral density
Study 32495016 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36384493 — Predictive Biomarker (PRD): NUBP1 mRNA
Genes: NUBP1; NBP; NBP1
Study 32090511 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32090511 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34265066 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 34087466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33064207 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 96008295 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 96008295 — Monitoring Biomarker (MOI): HBV DNA
Study 96008295 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 33426570 — Safety Biomarker (SAF): Hyaluronic acid
Study 33248578 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33248578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33248578 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 34352588 — Predictive Biomarker (PRD): TRAF6 mRNA
Genes: TRAF6; RNF85
Study 36379585 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 36379585 — Surrogate Endpoint (SUR): Blood pressure
Study 32123969 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 33100049 — Surrogate Endpoint (SUR): Blood pressure
Study 36384950 — Surrogate Endpoint (SUR): Blood pressure
Study 35197411 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 35197411 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35197411 — Surrogate Endpoint (SUR): Blood pressure
Study 35197411 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35197411 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33048034 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 35380374 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 36316939 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36316939 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 35973732 — Surrogate Endpoint (SUR): Blood pressure
Study 34862871 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34862871 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34862871 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34107473 — Surrogate Endpoint (SUR): Serum testosterone
Study 34633666 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 32937023 — Surrogate Endpoint (SUR): Blood pressure
Study 32937023 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33938936 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 34610254 — Surrogate Endpoint (SUR): Blood pressure
Study 35078574 — Predictive Biomarker (PRD): MMP14 mRNA
Genes: MMP14
Study 34605920 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34605920 — Surrogate Endpoint (SUR): Blood pressure
Study 34643808 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 34643808 — Surrogate Endpoint (SUR): Probing pocket depth
Study 35757326 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33837422 — Surrogate Endpoint (SUR): Blood pressure
Study 33635735 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35747237 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35747237 — Safety Biomarker (SAF): Hyaluronic acid
Study 33807135 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 36267872 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 32665587 — Surrogate Endpoint (SUR): Blood pressure
Study 35701800 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35701800 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32513905 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 32513905 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 34904132 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33964910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33964910 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36163942 — Predictive Biomarker (PRD): RARA mRNA
Genes: RARA; NR1B1
Study 32247709 — Surrogate Endpoint (SUR): Blood pressure
Study 35321823 — Predictive Biomarker (PRD): THEMIS mRNA
Genes: THEMIS; C6orf190; C6orf207
Study 32191532 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 35513384 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 33266325 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 32787676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 32588878 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 33385633 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 32124549 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 33823560 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33292892 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 35396602 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 34903440 — Surrogate Endpoint (SUR): Blood pressure
Study 35088103 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 32843299 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32843299 — Safety Biomarker (SAF): BDNF
Study 32385167 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 34393156 — Surrogate Endpoint (SUR): Bone mineral density
Study 34963099 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 34920723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33051340 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32100496 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 32100496 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 32100496 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32100496 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32100496 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32067817 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 35446282 — Predictive Biomarker (PRD): CPOX mRNA
Genes: CPOX; CPO; CPX
Study 35446282 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 33487255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33487255 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study 34397393 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 33477172 — Surrogate Endpoint (SUR): Blood pressure
Study 33581174 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33581174 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32483272 — Predictive Biomarker (PRD): TET1 mRNA
Genes: TET1; CXXC6; KIAA1676; LCX
Study 33893936 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 32873681 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 35557513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35557513 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33244872 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 33244872 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35093007 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36326771 — Surrogate Endpoint (SUR): Blood pressure
Study 35841457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34405737 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34405737 — Safety Biomarker (SAF): BDNF
Study 32461297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36108648 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33513242 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33950945 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 34489516 — Surrogate Endpoint (SUR): Blood pressure
Study 34489516 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33236646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34618482 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33870711 — Surrogate Endpoint (SUR): Blood pressure
Study 35306865 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35306865 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 35306865 — Surrogate Endpoint (SUR): Blood pressure
Study 34916216 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35429354 — Surrogate Endpoint (SUR): Blood pressure
Study 35175905 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34080585 — Predictive Biomarker (PRD): PAPSS2 mRNA
Genes: PAPSS2; ATPSK2
Study 34080585 — Predictive Biomarker (PRD): CHMP1B mRNA
Genes: CHMP1B; C18orf2
Study 34080585 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32686337 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 32686337 — Surrogate Endpoint (SUR): Bone mineral density
Study 36341847 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 33040702 — Surrogate Endpoint (SUR): Blood pressure
Study 33480963 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34907910 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study 34907910 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study 34907910 — Predictive Biomarker (PRD): VSIR mRNA
Genes: VSIR; C10orf54; SISP1; VISTA; PP2135; UNQ730/PRO1412
Study 34907910 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33951613 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33951613 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35674828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33052404 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 35013909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35013909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35013909 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 35013909 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 616864697 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 616864697 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 34444671 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32088687 — Surrogate Endpoint (SUR): Bacterial count
Study 33608835 — Safety Biomarker (SAF): Reactive oxygen species
Study 33608835 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 33749976 — Surrogate Endpoint (SUR): Blood pressure
Study 33322340 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 35545982 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35545982 — Surrogate Endpoint (SUR): Blood pressure
Study 33625064 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 33625064 — Predictive Biomarker (PRD): TMEM163 mRNA
Genes: TMEM163
Study 34524145 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33243160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33243160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33243160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33243160 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 33243160 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 33243160 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 33065462 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32611448 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study 33590270 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 34147462 — Surrogate Endpoint (SUR): Blood pressure
Study 36155117 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33158772 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 35351835 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 32320401 — Surrogate Endpoint (SUR): Serum uric acid
Study 32147225 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33973551 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 35275606 — Surrogate Endpoint (SUR): Blood pressure
Study 32945993 — Predictive Biomarker (PRD): ILK mRNA
Genes: ILK; ILK1; ILK2
Study 32945993 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34271366 — Surrogate Endpoint (SUR): Blood pressure
Study 34357396 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 35925531 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 35925531 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study 34259328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35052995 — Surrogate Endpoint (SUR): Probing pocket depth
Study 35738633 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 35738633 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 32960539 — Predictive Biomarker (PRD): RNASE2 mRNA
Genes: RNASE2; EDN; RNS2
Study 33559433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33559433 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 36014777 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study 36014777 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study 34158360 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35987996 — Surrogate Endpoint (SUR): Blood pressure
Study 33780264 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 36216952 — Surrogate Endpoint (SUR): Blood pressure
Study 35146797 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 35332795 — Predictive Biomarker (PRD): GDF11 mRNA
Genes: GDF11; BMP11
Study 35332812 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 35279948 — Safety Biomarker (SAF): Hyaluronic acid
Study 34321096 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 35504550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35504550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34569204 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 35887701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35887701 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 33265967 — Surrogate Endpoint (SUR): Blood pressure