TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05844124 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study NCT05844124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05738902 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT05215171 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study NCT05215171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05215171 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT04714151 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05249816 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05863442 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT03378414 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05680870 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study NCT05680870 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study NCT04837027 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study NCT04686227 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT05430945 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06115304 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05412524 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study NCT06332222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05194449 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06758960 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT06426082 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study NCT06759857 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06759857 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05890287 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05890287 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05504694 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT04957901 — Predictive Biomarker (PRD): RTEL1 mRNA
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study NCT04531670 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study NCT06463171 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06069102 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06497556 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05414084 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06099821 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04953078 — Predictive Biomarker (PRD): VAX1 mRNA
Genes: VAX1
Study NCT04897282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06581757 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT06008093 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study NCT06008093 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06450769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06450769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06510283 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study NCT05633914 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06504147 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04873362 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00001078 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06122415 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05160636 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05909943 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT05909943 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT05379920 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05354089 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04830800 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05118516 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT05683301 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06233734 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05373719 — Predictive Biomarker (PRD): Cyclin-dependent kinase-like 5
Genes: CDKL5; STK9
Study NCT05569096 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT05569096 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study NCT05067283 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05305911 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT00523276 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05392894 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study NCT05392894 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05992480 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06408246 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05997719 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06188559 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06188559 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04722328 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06342024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06342024 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT06342024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06342024 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT05549661 — Predictive Biomarker (PRD): PLK1 mRNA
Genes: PLK1; PLK
Study NCT05890911 — Predictive Biomarker (PRD): NADPH oxidase activator 1
Genes: NOXA1; P51NOX
Study NCT06178159 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04391309 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT04150198 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06567015 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06465732 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT06465732 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT06465732 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT06233357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06233357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05802108 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT05557903 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT06125028 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT05985382 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT05825417 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT06383884 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study NCT06383884 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06383884 — Predictive Biomarker (PRD): CD74 mRNA
Genes: CD74; DHLAG
Study NCT06383884 — Predictive Biomarker (PRD): SDC4 mRNA
Genes: SDC4
Study NCT06383884 — Predictive Biomarker (PRD); Safety Biomarker (SAF): RBPMS mRNA
Genes: RBPMS; HERMES
Study NCT06383884 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05385848 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT04762459 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05322096 — Predictive Biomarker (PRD): MCHR1 mRNA
Genes: MCHR1; GPR24; SLC1
Study NCT05775744 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04729465 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04979884 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT06140186 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06140186 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05095519 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04618978 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06027541 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06027541 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00000824 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04254640 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06348407 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT05349058 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT05349058 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT06254599 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04667234 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06759623 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05403710 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT05126602 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04853043 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT04853043 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT04853043 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04853043 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT04853043 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05265819 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT05263193 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT05158712 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT06184048 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06184048 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05462574 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT06472739 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05227716 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05862272 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06063668 — Predictive Biomarker (PRD): ENPP2 mRNA
Genes: ENPP2; ATX; PDNP2
Study NCT06614439 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study NCT04969861 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT05149014 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06042725 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT06203912 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06203912 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05113459 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06208501 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05618535 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05365659 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06389006 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06389006 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06367543 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06711523 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00002006 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06015100 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06071819 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT06711289 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05407727 — Predictive Biomarker (PRD): SCN2A mRNA
Genes: SCN2A; NAC2; SCN2A1; SCN2A2
Study NCT06711692 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06108258 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT06713980 — Predictive Biomarker (PRD): ST18 mRNA
Genes: ST18; KIAA0535; ZNF387
Study NCT06205706 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study NCT06205706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06713044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05218278 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study NCT04149418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06132633 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00002262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06713902 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04768348 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04768348 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study NCT06711146 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06446141 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT05643235 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT06583850 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study NCT05457699 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05210894 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT04140448 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05715814 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05195866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06000735 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05160467 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05043259 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05198388 — Safety Biomarker (SAF): Interleukin 1
Study NCT05677659 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study NCT04598334 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT05767203 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study NCT05828992 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT05279872 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04713540 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05185258 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT05372003 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT06376890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06376890 — Safety Biomarker (SAF): Connecting peptide
Genes: AHSG; FETUA; PRO2743
Study NCT06376890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06376890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05246033 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study NCT06132230 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study NCT05161494 — Predictive Biomarker (PRD): STXBP1 mRNA
Genes: STXBP1; UNC18A
Study NCT05835050 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT04704141 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT05624827 — Predictive Biomarker (PRD): TAFA4 mRNA
Genes: TAFA4; FAM19A4
Study NCT05624827 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): miR-124
Study NCT06331000 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT06392763 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT04798235 — Predictive Biomarker (PRD): HEXA mRNA
Genes: HEXA
Study NCT06194006 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT00859001 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT05196360 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study NCT06021678 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT05717582 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06469177 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study NCT04928534 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study NCT05660031 — Predictive Biomarker (PRD): LHB mRNA
Genes: LHB
Study NCT05877079 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study NCT06211413 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05009836 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00320567 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06228404 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05941273 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05876728 — Predictive Biomarker (PRD): FNDC5 mRNA
Genes: FNDC5; FRCP2
Study NCT05876728 — Predictive Biomarker (PRD): ESRRA mRNA
Genes: ESRRA; ERR1; ESRL1; NR3B1
Study NCT05876728 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02575508 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT05929807 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study NCT06402435 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05652777 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04828798 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study NCT06270719 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT05489575 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04768062 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06348056 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study NCT06104748 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study NCT06177314 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study NCT05990582 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04764656 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06041841 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study NCT06041841 — Predictive Biomarker (PRD): PCSK1 mRNA
Genes: PCSK1; NEC1
Study NCT06041841 — Predictive Biomarker (PRD): LEPROT mRNA
Genes: LEPROT; LEPR; OBR
Study NCT05622292 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06359860 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT06359860 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT06359860 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT06359860 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study NCT06359860 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT06359860 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT06094049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT05331495 — Predictive Biomarker (PRD): CIRBP mRNA
Genes: CIRBP; A18HNRNP; CIRP
Study NCT05044130 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05044130 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study NCT05044130 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT04835584 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT04917718 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT04917718 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04772391 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05549024 — Predictive Biomarker (PRD): GRPR mRNA
Genes: GRPR
Study NCT05729919 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study NCT05207787 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT06248606 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05630339 — Surrogate Endpoint (SUR): Serum calcium
Study NCT06121570 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06409650 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT05013177 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05171933 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT05015920 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04808882 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00435565 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study NCT05692258 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04765774 — Surrogate Endpoint (SUR): Blood pressure