TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32291608 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 32291608 — Predictive Biomarker (PRD): RPS7 mRNA
Genes: RPS7
Study 32291608 — Predictive Biomarker (PRD): TGFBR1 mRNA
Genes: TGFBR1; ALK5; SKR4
Study 32291608 — Predictive Biomarker (PRD): COX7B mRNA
Genes: COX7B
Study 32986531 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 36216413 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 36429677 — Predictive Biomarker (PRD): LIPE mRNA
Genes: LIPE
Study 32011496 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32011496 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 36501004 — Surrogate Endpoint (SUR): Bone mineral density
Study 32462276 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34473302 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 34473302 — Safety Biomarker (SAF): Uromodulin
Genes: UMOD
Study 34473302 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 34473302 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 34473302 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33077708 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34739635 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 34739635 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34739635 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 34739635 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 34739635 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 34739635 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 34739635 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 34556382 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 34992671 — Surrogate Endpoint (SUR): Blood pressure
Study 35113238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34480785 — Surrogate Endpoint (SUR): Blood pressure
Study 35862082 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35862082 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35862082 — Surrogate Endpoint (SUR): Blood pressure
Study 33914057 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 33914057 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 33914057 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 33914057 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 34756518 — Surrogate Endpoint (SUR): Blood pressure
Study 32468579 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 32468579 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34662695 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 37714931 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37714931 — Surrogate Endpoint (SUR): Blood pressure
Study 37714931 — Surrogate Endpoint (SUR): Bone mineral density
Study 35613998 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33382352 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33080408 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33080408 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 33439974 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35418429 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34672847 — Surrogate Endpoint (SUR): Blood pressure
Study 32721210 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 34234141 — Monitoring Biomarker (MOI): Cell-free DNA
Study 35533737 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 36053717 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34376554 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34376554 — Predictive Biomarker (PRD): KDM1A mRNA
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study 34376554 — Predictive Biomarker (PRD): PIK3R6 mRNA
Genes: PIK3R6; C17orf38
Study 36239289 — Surrogate Endpoint (SUR): Blood pressure
Study 33525659 — Predictive Biomarker (PRD): ELOVL5 mRNA
Genes: ELOVL5; ELOVL2; PRO0530
Study 35085038 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34335138 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 33788486 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34990208 — Predictive Biomarker (PRD): Microsatellite instability
Study 33119048 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 32590137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32590137 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 32590137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34903380 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33285745 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 33285745 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33061822 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33061822 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35397798 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 35397798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35107023 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 35107023 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35107023 — Surrogate Endpoint (SUR): Blood pressure
Study 35241243 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36209764 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 32614825 — Surrogate Endpoint (SUR): Bone mineral density
Study 33167780 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34350569 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33999472 — Predictive Biomarker (PRD): SLC22A4 mRNA
Genes: SLC22A4; ETT; OCTN1; UT2H
Study 32502940 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32502940 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32502940 — Predictive Biomarker (PRD): Hormone receptor
Study 32502940 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32935171 — Surrogate Endpoint (SUR): Bone mineral density
Study 32589978 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 32589978 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32589978 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 33860579 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 36163925 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 32492087 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 33651341 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 36131137 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 33170417 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 34899429 — Predictive Biomarker (PRD): MAP3K10 mRNA
Genes: MAP3K10; MLK2; MST
Study 34040191 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 33183774 — Predictive Biomarker (PRD): DPEP1 mRNA
Genes: DPEP1; MDP; RDP
Study 32476255 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32476255 — Surrogate Endpoint (SUR): Blood pressure
Study 33826539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33386797 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 35703293 — Surrogate Endpoint (SUR): Blood pressure
Study 32985509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32985509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32859157 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 616874113 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32154887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34816585 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34816585 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33234812 — Surrogate Endpoint (SUR): Blood pressure
Study 35696440 — Surrogate Endpoint (SUR): Blood pressure
Study 35129523 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33009489 — Predictive Biomarker (PRD): MSLN mRNA
Genes: MSLN; MPF
Study 33009489 — Predictive Biomarker (PRD): ARG2 mRNA
Genes: ARG2
Study 33009489 — Predictive Biomarker (PRD): FGF8 mRNA
Genes: FGF8; AIGF
Study 33009489 — Predictive Biomarker (PRD): KLK3 mRNA
Genes: KLK3; APS
Study 33009489 — Predictive Biomarker (PRD): ESRP2 mRNA
Genes: ESRP2; RBM35B; PP7059
Study 33009489 — Predictive Biomarker (PRD): NPR3 mRNA
Genes: NPR3; ANPRC; C5orf23; NPRC
Study 33009489 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 33009489 — Predictive Biomarker (PRD); Safety Biomarker (SAF): WNT5A mRNA
Genes: WNT5A
Study 33836974 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33836974 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 33836974 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32927478 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 33610734 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study 34496448 — Predictive Biomarker (PRD): KCNN1 mRNA
Genes: KCNN1; SK
Study 32408905 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 35631240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35631240 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35631240 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34776172 — Surrogate Endpoint (SUR): Blood pressure
Study 35692883 — Surrogate Endpoint (SUR): Bone mineral density
Study 35400202 — Surrogate Endpoint (SUR): Blood pressure
Study 35400202 — Surrogate Endpoint (SUR): Serum creatinine
Study 36333773 — Surrogate Endpoint (SUR): Pathological complete response
Study 32060651 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32013825 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35660972 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33386288 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 34560136 — Surrogate Endpoint (SUR): Serum creatinine
Study 35256034 — Predictive Biomarker (PRD): STXBP6 mRNA
Genes: STXBP6; HSPC156
Study 35256034 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 36220461 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 36220461 — Surrogate Endpoint (SUR): Pathological complete response
Study 32893328 — Predictive Biomarker (PRD): MBTPS1 mRNA
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 33713235 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33713235 — Safety Biomarker (SAF): BDNF
Study 35836691 — Surrogate Endpoint (SUR): Blood pressure
Study 35997951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35997951 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34791048 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34791048 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34791048 — Surrogate Endpoint (SUR): Bone mineral density
Study 33245323 — Surrogate Endpoint (SUR): Blood pressure
Study 35491679 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 33367869 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 35914913 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 36221135 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34364301 — Surrogate Endpoint (SUR): Blood pressure
Study 33531017 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 36424705 — Predictive Biomarker (PRD): PALD1 mRNA
Genes: PALD1; KIAA1274; PALD
Study 34648118 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 36175142 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 32143995 — Surrogate Endpoint (SUR): Bone mineral density
Study 32143995 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32232482 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36314174 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35871638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35871638 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 35012455 — Safety Biomarker (SAF): CYP11B1 mRNA
Genes: CYP11B1; S11BH
Study 34949967 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 36076192 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34287979 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 33211314 — Predictive Biomarker (PRD): Hormone receptor
Study 33227441 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34062261 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 34988583 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34554243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32344098 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32344098 — Safety Biomarker (SAF): BDNF
Study 33487304 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34388179 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 34965950 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34965950 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 34965950 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35841410 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33763789 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 32696226 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 33429768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32195959 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34274496 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 34621052 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 36199064 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 36199064 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 36199064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36199064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36199064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36348358 — Surrogate Endpoint (SUR): Blood pressure
Study 32621487 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 35131532 — Safety Biomarker (SAF): Hyaluronic acid
Study 36335780 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 32034481 — Surrogate Endpoint (SUR): Blood pressure
Study 35758258 — Predictive Biomarker (PRD): F2RL3 mRNA
Genes: F2RL3; PAR4
Study 32449174 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 32571399 — Surrogate Endpoint (SUR): Blood pressure
Study 36217131 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 32453453 — Surrogate Endpoint (SUR): Blood pressure
Study 34203033 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32044999 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35412211 — Predictive Biomarker (PRD): CGN mRNA
Genes: CGN; KIAA1319
Study 35766283 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 34433118 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 34433118 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 32353052 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33852173 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 33852173 — Predictive Biomarker (PRD): GIPR mRNA
Genes: GIPR
Study 35868987 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 35868987 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 35868987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34327591 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 35202621 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 616670506 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 34127003 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 32234329 — Predictive Biomarker (PRD): SLC10A2 mRNA
Genes: SLC10A2; ASBT; ISBT; NTCP2
Study 32234329 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33784020 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 34423919 — Safety Biomarker (SAF): Interleukin 1
Study 35147466 — Surrogate Endpoint (SUR): Blood pressure
Study 33906652 — Monitoring Biomarker (MOI): Procalcitonin
Study 33906652 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34190716 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 34190716 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 35857037 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 35857037 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 35857037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35857037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32349893 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32349893 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32349893 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32349893 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33108244 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35682461 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 35251575 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 34614209 — Predictive Biomarker (PRD): Hormone receptor
Study 32912445 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36173649 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 33663235 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33663235 — Surrogate Endpoint (SUR): Serum creatinine
Study 32715482 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32715482 — Surrogate Endpoint (SUR): Blood pressure
Study 33000285 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33000285 — Surrogate Endpoint (SUR): Serum calcium
Study 33000285 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 33000285 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 33724542 — Surrogate Endpoint (SUR): Bone mineral density
Study 35510814 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 33328333 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 33328333 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33328333 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 33938493 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 32748630 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 32084330 — Predictive Biomarker (PRD): LIME1 mRNA
Genes: LIME1; LIME; LP8067
Study 32084330 — Predictive Biomarker (PRD): ZGPAT mRNA
Genes: ZGPAT; GPATC6; GPATCH6; KIAA1847; ZC3H9; ZC3HDC9; ZIP
Study 32084330 — Predictive Biomarker (PRD): PGAP3 mRNA
Genes: PGAP3; CAB2; PERLD1; UNQ546/PRO1100
Study 32084330 — Predictive Biomarker (PRD): EML3 mRNA
Genes: EML3
Study 32084330 — Predictive Biomarker (PRD): AHNAK mRNA
Genes: AHNAK; PM227
Study 33200812 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36104929 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 33328161 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 35101110 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 35101110 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33738656 — Surrogate Endpoint (SUR): Pathological complete response
Study 35014069 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 33549435 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 35277540 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 35277540 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 35277540 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32847980 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45