TrialPanorama/TrialPanorama-database huggingface dataset:
Study 39676868 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39677360 — Monitoring Biomarker (MOI): Procalcitonin
Study 39677360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39679006 — Surrogate Endpoint (SUR): Blood pressure
Study 39681164 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ERCC2
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 39683419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39683612 — Surrogate Endpoint (SUR): Bone mineral density
Study 39684943 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 39686497 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 39686614 — Surrogate Endpoint (SUR): Blood pressure
Study 39687670 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 39688776 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 39689146 — Surrogate Endpoint (SUR): Blood pressure
Study 39689295 — Surrogate Endpoint (SUR): Blood pressure
Study 39689939 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 39689940 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 39689992 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 39691156 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 39692004 — Surrogate Endpoint (SUR): Pathological complete response
Study 39692817 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 39693081 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 39693244 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 39693244 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 39693245 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 39693245 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 39693611 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 39693611 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 39693827 — Surrogate Endpoint (SUR): Forced vital capacity
Study 39694207 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 39694207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39694415 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 39694573 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39694678 — Surrogate Endpoint (SUR): Blood pressure
Study 39694978 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 39695262 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 39695768 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 39695768 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 39695768 — Predictive Biomarker (PRD): MRPL36 mRNA
Genes: MRPL36; BRIP1
Study 39695768 — Predictive Biomarker (PRD): RAD51C mRNA
Genes: RAD51C; RAD51L2
Study 39695768 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study 39695768 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 39695768 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 39695768 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCNE1 mRNA
Genes: CCNE1; CCNE
Study 39696211 — Surrogate Endpoint (SUR): Blood pressure
Study 39696526 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 39696526 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 39696680 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study 39696680 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 39697201 — Monitoring Biomarker (MOI): HBV DNA
Study 39697325 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 39697344 — Predictive Biomarker (PRD): TLR8 mRNA
Genes: TLR8; UNQ249/PRO286
Study 39697620 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 39697620 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39697620 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 39697620 — Predictive Biomarker (PRD): Hormone receptor
Study 39697813 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 39697865 — Surrogate Endpoint (SUR): Blood pressure
Study 39698150 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 39698150 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 39698346 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 39700102 — Surrogate Endpoint (SUR): Blood pressure
Study 39700313 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 39700502 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 39700502 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 39701097 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 39702205 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 39702318 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 39702584 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 39703564 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39703741 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 39703741 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 39704227 — Predictive Biomarker (PRD): SCAI mRNA
Genes: SCAI; C9orf126
Study 39704227 — Surrogate Endpoint (SUR): Blood pressure
Study 39704778 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 39704778 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 39704778 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 39704778 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 39704778 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 39705540 — Predictive Biomarker (PRD): Induced myeloid leukemia cell differentiation protein Mcl-1
Genes: MCL1; BCL2L3
Study 39705540 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 39705694 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39705855 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 39706335 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 39706666 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 39706803 — Predictive Biomarker (PRD): Hormone receptor
Study 39707032 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 39707042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 39707077 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 39707077 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 39707077 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 39707077 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 39707138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39707158 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 39707158 — Surrogate Endpoint (SUR): Blood pressure
Study 39707490 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 39707531 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study 39707531 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 39707595 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 39707595 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39708052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39708369 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 39709140 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 39709368 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 39710171 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study 39710171 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 39710352 — Predictive Biomarker (PRD): IVL mRNA
Genes: IVL
Study 39710508 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 39710693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39710697 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 39711285 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 39711702 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 39712455 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39712455 — Predictive Biomarker (PRD): Hormone receptor
Study 39713266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 39713266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 39713935 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 39713935 — Predictive Biomarker (PRD): MFF mRNA
Genes: MFF; C2orf33; AD030; AD033; GL004
Study 39714033 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 39714546 — Surrogate Endpoint (SUR): Forced vital capacity
Study 39715748 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 39715755 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 39715755 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 39715755 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 39716203 — Surrogate Endpoint (SUR): Blood pressure
Study 39716323 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 39716323 — Predictive Biomarker (PRD): SERPINF1 mRNA
Genes: SERPINF1; PEDF; PIG35
Study 39716323 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 39716323 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 39716323 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 39716442 — Predictive Biomarker (PRD): ITGA4 mRNA
Genes: ITGA4; CD49D
Study 39716442 — Predictive Biomarker (PRD): CD79B mRNA
Genes: CD79B; B29; IGB
Study 39716442 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 39716442 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study 39716442 — Predictive Biomarker (PRD): Induced myeloid leukemia cell differentiation protein Mcl-1
Genes: MCL1; BCL2L3
Study 39716659 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 39716659 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 39716659 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 39717281 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 39717667 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 39717777 — Safety Biomarker (SAF): Th2 cell
Study 39717874 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 39717874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 39718599 — Surrogate Endpoint (SUR): Blood pressure
Study 39719282 — Surrogate Endpoint (SUR): Blood pressure
Study 39719323 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 39719429 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 39719625 — Predictive Biomarker (PRD): EBP mRNA
Genes: EBP
Study 39720510 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 39720677 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 39720677 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 39720677 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 39722560 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 39722592 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 39722695 — Surrogate Endpoint (SUR): Bone mineral density
Study 39723608 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 39723608 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 39723627 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39724015 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 39724200 — Surrogate Endpoint (SUR): Blood pressure
Study 39725584 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 39725988 — Surrogate Endpoint (SUR): Blood pressure
Study 39726942 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 39727053 — Surrogate Endpoint (SUR): Blood pressure
Study 39727210 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 39727283 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 39728301 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 39728301 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 39728301 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 39729067 — Surrogate Endpoint (SUR): Blood pressure
Study 39729347 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 39729390 — Predictive Biomarker (PRD): SAMHD1 mRNA
Genes: SAMHD1; MOP5
Study 39729677 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 39729677 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 39730000 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 39730000 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39730000 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 39730001 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 39730001 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 39730694 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 39731908 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 39731909 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 39731909 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 39731909 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39731909 — Predictive Biomarker (PRD): Hormone receptor
Study 39732365 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 39732365 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 39732398 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 39732398 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 39732437 — Surrogate Endpoint (SUR): Blood pressure
Study 39732649 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 39734708 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 39734743 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 39734743 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 39734743 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 39734743 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 39734743 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 39734743 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 39734743 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 39734743 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 39734743 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 39735403 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 39735417 — Predictive Biomarker (PRD): CXCR1 mRNA
Genes: CXCR1; CMKAR1; IL8RA
Study 39737062 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 39737219 — Predictive Biomarker (PRD): SERPINB3 mRNA
Genes: SERPINB3; SCCA; SCCA1
Study 39737219 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 39737542 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 39737542 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 39737640 — Predictive Biomarker (PRD): SOAT1 mRNA
Genes: SOAT1; ACACT; ACACT1; ACAT; ACAT1; SOAT; STAT
Study 39737895 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 39737899 — Predictive Biomarker (PRD): PSCA mRNA
Genes: PSCA; UNQ206/PRO232
Study 39737899 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 39738931 — Predictive Biomarker (PRD): FOXL2 mRNA
Genes: FOXL2
Study 39738931 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 39739628 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 39739628 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study 39739907 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 39739907 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 39739975 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 39739975 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 39739990 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 39739990 — Surrogate Endpoint (SUR): Blood pressure
Study 39740313 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 39740313 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 39740666 — Surrogate Endpoint (SUR): Annualized growth velocity
Study 39740941 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 39741233 — Predictive Biomarker (PRD): CHKA mRNA
Genes: CHKA; CHK; CKI
Study 39742565 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 39742565 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 39742565 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 39742894 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 39742894 — Safety Biomarker (SAF): BDNF
Study 39742894 — Safety Biomarker (SAF): IL-6 and IL-10
Study 39743436 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 39743478 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 39743478 — Monitoring Biomarker (MOI): Cell-free DNA
Study 39743478 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 39744082 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 39744679 — Predictive Biomarker (PRD): S100A1 mRNA
Genes: S100A1; S100A
Study 39745261 — Predictive Biomarker (PRD): Tripeptidyl-peptidase I
Genes: TPP1; CLN2; GIG1; UNQ267/PRO304
Study 39745404 — Surrogate Endpoint (SUR): Blood pressure
Study 39745526 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 39746212 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 39746473 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 39746515 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 39747123 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 39747123 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 39747932 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 39747998 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 39748428 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 39748491 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 39748640 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 39749040 — Surrogate Endpoint (SUR): Blood pressure
Study 39749650 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 39749650 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 39749650 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 39751962 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 39753962 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 39754194 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 39754932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 39754932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 39754976 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 39754976 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 39754976 — Predictive Biomarker (PRD): Hormone receptor
Study 39755168 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 39755582 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 39755716 — Surrogate Endpoint (SUR): Blood pressure
Study 39755925 — Predictive Biomarker (PRD): CLK1 mRNA
Genes: CLK1; CLK
Study 39755925 — Predictive Biomarker (PRD): DYRK1A mRNA
Genes: DYRK1A; DYRK; MNB; MNBH
Study 39756156 — Predictive Biomarker (PRD): MTAP mRNA
Genes: MTAP; MSAP
Study 39756424 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 39756424 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 39756425 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 39756425 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 39756446 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 39756446 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 39756446 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 39756446 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 39756820 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 39757186 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1