TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35722876 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 35724695 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 35724798 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35725262 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 35725623 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 35726608 — Predictive Biomarker (PRD): WDR62 mRNA
Genes: WDR62; C19orf14
Study 35727209 — Surrogate Endpoint (SUR): Serum creatinine
Study 35727334 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 35727476 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 35727609 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35727629 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35728046 — Predictive Biomarker (PRD): Hormone receptor
Study 35728342 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35728746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 35728910 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 35729005 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35729900 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35732222 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35732441 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 35734087 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 35736816 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35736816 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 35737291 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 35737298 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 35737460 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 35737639 — Predictive Biomarker (PRD): KDM1A mRNA
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study 35737873 — Surrogate Endpoint (SUR): Hematologic response
Study 35738747 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35738999 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 35738999 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 35738999 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 35739300 — Safety Biomarker (SAF): XRCC1
Genes: RCC
Study 35739539 — Predictive Biomarker (PRD): GPD1L mRNA
Genes: GPD1L; KIAA0089
Study 35740079 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 35740079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35740079 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35740079 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 35740079 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35740322 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35740603 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35741698 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 35747196 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 35747402 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 35747712 — Surrogate Endpoint (SUR): Pathological complete response
Study 35747889 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 35748318 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 35748699 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 35748699 — Predictive Biomarker (PRD): PSMB7 mRNA
Genes: PSMB7; Z
Study 35748853 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35749284 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 35750354 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 35750419 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 35750422 — Surrogate Endpoint (SUR): Blood pressure
Study 35750559 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 35751748 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35751748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35752194 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35752286 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 35752286 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 35752539 — Surrogate Endpoint (SUR): Blood pressure
Study 35753512 — Predictive Biomarker (PRD): SASH3 mRNA
Genes: SASH3; CXorf9; SLY
Study 35756843 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35756843 — Predictive Biomarker (PRD): STING1 mRNA
Genes: STING1; ERIS; MITA; STING; TMEM173
Study 35759134 — Predictive Biomarker (PRD): CLDN6 mRNA
Genes: CLDN6; UNQ757/PRO1488
Study 35762292 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 35763235 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 35763342 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 35763768 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 35764393 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35764638 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 35764638 — Predictive Biomarker (PRD): HMGA2 mRNA
Genes: HMGA2; HMGIC
Study 35764638 — Predictive Biomarker (PRD): IL2RG mRNA
Genes: IL2RG
Study 35764773 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 35764796 — Surrogate Endpoint (SUR): Blood pressure
Study 35765007 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35765055 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study 35765145 — Monitoring Biomarker (MOI): Cell-free DNA
Study 35766394 — Surrogate Endpoint (SUR): Pathological complete response
Study 35766641 — Surrogate Endpoint (SUR): Blood pressure
Study 35766976 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 35767123 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 35767205 — Predictive Biomarker (PRD): TYRO3 mRNA
Genes: TYRO3; BYK; DTK; RSE; SKY; TIF
Study 35767205 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 35767205 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 35767435 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35768859 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35768859 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35769080 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35769368 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35770218 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 35770220 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 35770681 — Monitoring Biomarker (MOI): HBV DNA
Study 35771259 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 35771259 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35771301 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35771573 — Predictive Biomarker (PRD): ASPRV1 mRNA
Genes: ASPRV1; SASP
Study 35771992 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2
Study 35772170 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 35772429 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study 35772429 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35772833 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35772852 — Predictive Biomarker (PRD): Tripeptidyl-peptidase I
Genes: TPP1; CLN2; GIG1; UNQ267/PRO304
Study 35772853 — Surrogate Endpoint (SUR): Blood pressure
Study 35772853 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35773363 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 35773649 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 35774109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35775373 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 35775390 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 35776072 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 35776072 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 35776072 — Predictive Biomarker (PRD): TTLL5 mRNA
Genes: TTLL5; KIAA0998; STAMP
Study 35776144 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 35776185 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35776199 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 35776199 — Predictive Biomarker (PRD): DCLRE1C mRNA
Genes: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C
Study 35776269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35776489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35776489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35776489 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 35776489 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 35776489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35776909 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 35778519 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 35778568 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 35778568 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 35778568 — Safety Biomarker (SAF): Reactive oxygen species
Study 35778636 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35778636 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 35778636 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 35778703 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 35778703 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 35779095 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 35779669 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 35780200 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 35780200 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 35780200 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 35780200 — Predictive Biomarker (PRD): TNFRSF13C mRNA
Genes: TNFRSF13C; BAFFR; BR3
Study 35781099 — Predictive Biomarker (PRD): ROCK2 mRNA
Genes: ROCK2; KIAA0619
Study 35782928 — Predictive Biomarker (PRD): ZPR1 mRNA
Genes: ZPR1; ZNF259
Study 35782928 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35783648 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35783649 — Surrogate Endpoint (SUR): Blood pressure
Study 35783836 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 35784545 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 35784580 — Surrogate Endpoint (SUR): Blood pressure
Study 35784641 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35786528 — Predictive Biomarker (PRD): SAMHD1 mRNA
Genes: SAMHD1; MOP5
Study 35786544 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 35787807 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 35788366 — Predictive Biomarker (PRD): DARS1 mRNA
Genes: DARS1; DARS; PIG40
Study 35788722 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35788722 — Surrogate Endpoint (SUR): Pathological complete response
Study 35789261 — Monitoring Biomarker (MOI): HBV DNA
Study 35790143 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 35791008 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35794169 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 35794343 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 35794623 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 35794623 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 35794623 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 35794623 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35794669 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35794781 — Surrogate Endpoint (SUR): Blood pressure
Study 35794781 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35794781 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35795028 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35795028 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35795231 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 35795492 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 35797012 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35797012 — Predictive Biomarker (PRD): Hormone receptor
Study 35797012 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 35798000 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35798027 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 35798241 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35798241 — Surrogate Endpoint (SUR): Serum creatinine
Study 35798532 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35798532 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35798532 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35798714 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 35799290 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 35799394 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 35799791 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 35801187 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 35801187 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35802628 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35802628 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 35802628 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35802628 — Safety Biomarker (SAF): BDNF
Study 35803260 — Predictive Biomarker (PRD): MAGEA1 mRNA
Genes: MAGEA1; MAGE1; MAGE1A
Study 35803260 — Predictive Biomarker (PRD): KLRG1 mRNA
Genes: KLRG1; CLEC15A; MAFA; MAFAL
Study 35803286 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 35803286 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 35803835 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35803835 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 35803835 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 35805716 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 35806269 — Safety Biomarker (SAF): Interleukin 1
Study 35806269 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 35810243 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 35810296 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35810296 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 35810311 — Predictive Biomarker (PRD): SH2D1A mRNA
Genes: SH2D1A; DSHP; SAP
Study 35810553 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35812443 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 35814366 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 35815359 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 35815644 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study 35816241 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 35816490 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 35816951 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35817031 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 35817031 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 35817480 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 35818046 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 35818348 — Safety Biomarker (SAF): PPOX
Genes: HCRT; OX
Study 35819199 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35819312 — Predictive Biomarker (PRD): DIABLO mRNA
Genes: DIABLO; SMAC
Study 35819312 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 35819312 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 35819325 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 35819446 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 35819446 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 35819446 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 35819446 — Safety Biomarker (SAF): miR-146b
Genes: MIR146B
Study 35819446 — Predictive Biomarker (PRD): IL23R
Genes: IL-23R
Study 35820227 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 35820397 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35820397 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 35820718 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35820779 — Predictive Biomarker (PRD): PLIN2 mRNA
Genes: PLIN2; ADFP
Study 35820779 — Predictive Biomarker (PRD): RAB14 mRNA
Genes: RAB14
Study 35820779 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 35820779 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35820889 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 35820889 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 35820889 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study 35820889 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 35820889 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 35821844 — Safety Biomarker (SAF): Reactive oxygen species
Study 35822301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35822301 — Monitoring Biomarker (MOI): Procalcitonin
Study 35822301 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 35829780 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35830474 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 35830474 — Monitoring Biomarker (MOI): Procalcitonin
Study 35830474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35831043 — Predictive Biomarker (PRD): CSAD mRNA
Genes: CSAD; CSD
Study 35832286 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35832447 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35832447 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 35833116 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 35835008 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35835061 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 35835491 — Surrogate Endpoint (SUR): Blood pressure
Study 35835523 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 35835611 — Predictive Biomarker (PRD): Microsatellite instability
Study 35836289 — Predictive Biomarker (PRD): YAP1 mRNA
Genes: YAP1; YAP65
Study 35836289 — Predictive Biomarker (PRD): TOMM20 mRNA
Genes: TOMM20; KIAA0016
Study 35836289 — Predictive Biomarker (PRD): CSMD1 mRNA
Genes: CSMD1; KIAA1890; UNQ5952/PRO19863
Study 35836289 — Predictive Biomarker (PRD): DAXX mRNA
Genes: DAXX; BING2; DAP6
Study 35836289 — Predictive Biomarker (PRD): ARL4D mRNA
Genes: ARL4D; ARF4L
Study 35837099 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 35838207 — Pharmacodynamic Biomarker (PDY): 2-hydroxyglutarate
Study 35838207 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 35839426 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 35839426 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35839426 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 35839786 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 35839786 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 35840573 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35841038 — Predictive Biomarker (PRD): VCP mRNA
Genes: VCP
Study 35843096 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study 35843096 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study 35843439 — Surrogate Endpoint (SUR): Urinary oxalate
Study 35843546 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1