TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT06711510 — Predictive Biomarker (PRD): GRN mRNA
Genes: GRN
Study NCT05218369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06732908 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06722170 — Predictive Biomarker (PRD): OTOF mRNA
Genes: OTOF; FER1L2
Study NCT06733532 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06732895 — Surrogate Endpoint (SUR): Annualized growth velocity
Study NCT05698238 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT06121154 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study NCT06107465 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05279807 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05107544 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06752876 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06753682 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT05342025 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04648189 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04649866 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study NCT05286736 — Predictive Biomarker (PRD): EEF1A2 mRNA
Genes: EEF1A2; EEF1AL; STN
Study NCT06256172 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05011773 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05305352 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06713655 — Predictive Biomarker (PRD): PAX1 mRNA
Genes: PAX1; HUP48
Study NCT06723379 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT06722534 — Predictive Biomarker (PRD): STK11 mRNA
Genes: STK11; LKB1; PJS
Study NCT06152614 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04799054 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study NCT04672226 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study NCT06605664 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06605664 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06605664 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06181526 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT05298488 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04931264 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05804773 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05804773 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06083779 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04619979 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study NCT05823402 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05129241 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04905550 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06082713 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT04855344 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT06045910 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05707663 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT06091176 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04838262 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06588751 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05727345 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05564416 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT05160766 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05408962 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06627309 — Surrogate Endpoint (SUR): Hematologic response
Study NCT06684834 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06133322 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05599308 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06154109 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05529108 — Predictive Biomarker (PRD): BSG mRNA
Genes: BSG; UNQ6505/PRO21383
Study NCT05498155 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05228665 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05733702 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study NCT05733702 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study NCT05341531 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study NCT05341531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05341531 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT04655092 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT05578716 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study NCT06234579 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06145945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06145945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05468866 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT05468866 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study NCT05468866 — Predictive Biomarker (PRD): TNFSF4 mRNA
Genes: TNFSF4; TXGP1
Study NCT05468866 — Predictive Biomarker (PRD): CD226 mRNA
Genes: CD226; DNAM1
Study NCT05468866 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT05468866 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study NCT05468866 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT05468866 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study NCT05804669 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT06276998 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05987358 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT06369259 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT06369259 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study NCT06369259 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05703854 — Predictive Biomarker (PRD): IL15 mRNA
Genes: IL15
Study NCT06528366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06528366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06528366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00219804 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT05261126 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT05261126 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06561256 — Predictive Biomarker (PRD): COL17A1 mRNA
Genes: COL17A1; BP180; BPAG2
Study NCT05972551 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05299476 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05033054 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05103826 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04688658 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06305299 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study NCT06410352 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05126082 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05320081 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT06323512 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT06323512 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT05502133 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study NCT06180369 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT04549285 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04782063 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study NCT06610409 — Safety Biomarker (SAF): C-X-C motif chemokine 5
Genes: CXCL5; ENA78; SCYB5
Study NCT05022186 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT04946968 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04946968 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05184023 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05875025 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT06158295 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04544293 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06426550 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT06110663 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT06110663 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03629327 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03629327 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT05421611 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05195502 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT06094257 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT05741359 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05741359 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05325801 — Predictive Biomarker (PRD): GPRC5D mRNA
Genes: GPRC5D
Study NCT05811923 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT04649112 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04717986 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT04259424 — Predictive Biomarker (PRD): TIMM8A mRNA
Genes: TIMM8A; DDP; DDP1; TIM8A
Study NCT05586074 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05962684 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT05300347 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT05300347 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT05033769 — Predictive Biomarker (PRD): AIRE mRNA
Genes: AIRE; APECED
Study NCT06276868 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06276868 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05956132 — Predictive Biomarker (PRD): CAPN3 mRNA
Genes: CAPN3; CANP3; CANPL3; NCL1
Study NCT05976893 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT05033691 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06625606 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05667116 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06321861 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT06321861 — Predictive Biomarker (PRD): ADORA2A mRNA
Genes: ADORA2A; ADORA2
Study NCT05710666 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06153134 — Predictive Biomarker (PRD): MITF mRNA
Genes: MITF; BHLHE32
Study NCT06380322 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05489848 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT05489848 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT05830214 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT05105451 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05105451 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT05105451 — Safety Biomarker (SAF): BDNF
Study NCT00320827 — Predictive Biomarker (PRD): TNFRSF10B mRNA
Genes: TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186
Study NCT05727969 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05727969 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05880394 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06168552 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04524325 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05737537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05737537 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT05738135 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05161897 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04811274 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04811274 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study NCT05543187 — Predictive Biomarker (PRD): ATP8B1 mRNA
Genes: ATP8B1; ATPIC; FIC1; PFIC
Study NCT05691894 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05846347 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05846347 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05724589 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00000801 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04925349 — Predictive Biomarker (PRD): AMN mRNA
Genes: AMN; UNQ513/PRO1028
Study NCT04925349 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study NCT06363110 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03800056 — Predictive Biomarker (PRD): AIRE mRNA
Genes: AIRE; APECED
Study NCT05467592 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT05467592 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study NCT04837508 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05608603 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT05079165 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05208905 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05901545 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05382026 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06568562 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05769400 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05000957 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT06542198 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT05867628 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT04523116 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04523116 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05543954 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT06463561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06463561 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT06463561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05865015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT05396469 — Predictive Biomarker (PRD): MFAP4 mRNA
Genes: MFAP4
Study NCT05600296 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05384340 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05384340 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05345808 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05727761 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT05420298 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06121167 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT06121167 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT04604145 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05724732 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT05724732 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT06352580 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06298916 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT06430697 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06722911 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06724133 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT06724133 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study NCT06724562 — Predictive Biomarker (PRD): ACVR1 mRNA
Genes: ACVR1; ACVRLK2
Study NCT04946994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04946994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05534009 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06133387 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study NCT05782023 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04733521 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT05252650 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT05354817 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05175755 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06125847 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study NCT06125847 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05707806 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06668389 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06668389 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT06664099 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05020977 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05712473 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06515587 — Predictive Biomarker (PRD): FUT3 mRNA
Genes: FUT3; FT3B; LE
Study NCT06515587 — Predictive Biomarker (PRD): FUT2 mRNA
Genes: FUT2; SEC2
Study NCT06682260 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06682676 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study NCT06683040 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT06683040 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT05566223 — Predictive Biomarker (PRD): CISH mRNA
Genes: CISH; G18
Study NCT05549895 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04704908 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06682013 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06069076 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study NCT06366516 — Predictive Biomarker (PRD): DLX1 mRNA
Genes: DLX1
Study NCT06366516 — Predictive Biomarker (PRD): ITGA4 mRNA
Genes: ITGA4; CD49D
Study NCT06366516 — Predictive Biomarker (PRD): ZNF671 mRNA
Genes: ZNF671
Study NCT06564181 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05138458 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study NCT05000294 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05000294 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05665075 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT06079788 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT06097416 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00000658 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05503095 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT06257550 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05976555 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04987086 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05694923 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT06532643 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT06230822 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT06296017 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT05891847 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT05418582 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04102254 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study NCT05714098 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06062745 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05789888 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05789888 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT05223504 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06733064 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04892875 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06347887 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00227474 — Predictive Biomarker (PRD): TPBG mRNA
Genes: TPBG; 5T4
Study NCT06359691 — Surrogate Endpoint (SUR): Blood pressure