TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05753943 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT06266247 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04586283 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06474130 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study NCT05046509 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06243536 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT05362955 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT06651255 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT06652048 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05255900 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06006793 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06080594 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT06080594 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06118086 — Predictive Biomarker (PRD): MYB mRNA
Genes: MYB
Study NCT05304702 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04971434 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05039086 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT04737655 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT05994274 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04578444 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04578444 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03206814 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04591483 — Predictive Biomarker (PRD): ELOVL4 mRNA
Genes: ELOVL4
Study NCT06451406 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06653972 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06653985 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06587503 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03492918 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03492918 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study NCT05075070 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06366139 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT06007300 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study NCT06601153 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06591793 — Predictive Biomarker (PRD): MYO7A mRNA
Genes: MYO7A; USH1B
Study NCT04743102 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT06543199 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study NCT06543199 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05520970 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06617351 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06586359 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06620913 — Predictive Biomarker (PRD): DPYSL5 mRNA
Genes: DPYSL5; CRMP5; ULIP6
Study NCT05650736 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT05522491 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06620588 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT06620588 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study NCT05080023 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study NCT06408454 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT06678191 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT06694857 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06229795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04697875 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT04697875 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04365517 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04365517 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05556720 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06011187 — Predictive Biomarker (PRD): AFM mRNA
Genes: AFM; ALB2; ALBA
Study NCT06541860 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT05430399 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05044676 — Predictive Biomarker (PRD): CD226 mRNA
Genes: CD226; DNAM1
Study NCT04824924 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05895136 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04322383 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT05828147 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT05828147 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT05599893 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06201780 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT06201780 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study NCT06201780 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study NCT06201780 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study NCT05684627 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT05445778 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT04599556 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT05517252 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT06234605 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT04633278 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05085626 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05308602 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06567080 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05970770 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06012370 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06517667 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06182982 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05928195 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06236269 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06236269 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06236269 — Predictive Biomarker (PRD): TACSTD2 mRNA
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study NCT04098718 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT05447767 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05761028 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT04886232 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04960774 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT04960774 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study NCT06200103 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06041425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05964582 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05858307 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT04640909 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05687071 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05601401 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06498076 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04989231 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05092451 — Predictive Biomarker (PRD): IL15 mRNA
Genes: IL15
Study NCT04978675 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04815356 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT05893927 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06087055 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05785754 — Predictive Biomarker (PRD): CD93 mRNA
Genes: CD93; C1QR1; MXRA4
Study NCT06286748 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05376514 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05376514 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06654154 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06654154 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04979312 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06655259 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT06591416 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06586177 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT06497270 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04829422 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05606913 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06564649 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study NCT03063710 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03063710 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT04907760 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06359418 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06359418 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05165771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03976973 — Predictive Biomarker (PRD): MUC2 mRNA
Genes: MUC2; SMUC
Study NCT03976973 — Predictive Biomarker (PRD): MUC4 mRNA
Genes: MUC4
Study NCT03976973 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study NCT03976973 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT06347003 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study NCT06347003 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05919329 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06518278 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study NCT05756972 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05756972 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05169541 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study NCT05940220 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT05949333 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study NCT04951024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04951024 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT04676386 — Predictive Biomarker (PRD): PIR mRNA
Genes: PIR
Study NCT05434286 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT05434286 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT05374538 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05374538 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT05174559 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study NCT05099471 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT05099471 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study NCT06095063 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05640778 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05461209 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT05382351 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03963817 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT03963817 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05953701 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06548919 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06548919 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06277427 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06539767 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study NCT06539767 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05069311 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05069311 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT05069311 — Safety Biomarker (SAF): BDNF
Study NCT05845268 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05902247 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05670301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05670301 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study NCT05670301 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study NCT05286970 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06016504 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT04307329 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04718155 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06308276 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05882448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06542887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04671303 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00006066 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT06359509 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06107907 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06138132 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05877235 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT05805956 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06373458 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study NCT05810246 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT05810246 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT05288387 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05288387 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT05300178 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05349890 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT06556277 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT06541171 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT05830396 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study NCT06655064 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06654115 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04938128 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04061421 — Safety Biomarker (SAF): CDA
Genes: CDD
Study NCT05527054 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06595680 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT06319690 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06651047 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT06652555 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06594094 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04996121 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT06594445 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study NCT06594445 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT05363748 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05991778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05030831 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study NCT05030831 — Predictive Biomarker (PRD): ENPP1 mRNA
Genes: ENPP1; M6S1; NPPS; PC1; PDNP1
Study NCT06525844 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT05510596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04566133 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05386420 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05353270 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04999540 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05873374 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05338619 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06106464 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06106464 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06106464 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT05572775 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study NCT05747794 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06099236 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT06099236 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study NCT06099236 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06701734 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT06703268 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT06617988 — Predictive Biomarker (PRD): SIRT3 mRNA
Genes: SIRT3; SIR2L3
Study NCT05005234 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04137640 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06704126 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06316960 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT06297941 — Predictive Biomarker (PRD): MYB mRNA
Genes: MYB
Study NCT01196806 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06338956 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04982263 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT04125472 — Predictive Biomarker (PRD): PHC1 mRNA
Genes: PHC1; EDR1; PH1
Study NCT06471634 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04883827 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05043142 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05408910 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT06595212 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT05071690 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT05071690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06654206 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06503614 — Predictive Biomarker (PRD): KLRC1 mRNA
Genes: KLRC1; NKG2A
Study NCT04851548 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06237413 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05821790 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT05771337 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT06166186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04988802 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT06182852 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05485792 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05831787 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04640610 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04640610 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT04640610 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04595903 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04248413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04248413 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT05802719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06580431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06497205 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study NCT02194751 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05904769 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04928105 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT05279547 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04794829 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05465499 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT05435274 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1