TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32366139 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 35028547 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33105359 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33105359 — Safety Biomarker (SAF): BDNF
Study 33105359 — Safety Biomarker (SAF): IL-6 and IL-10
Study 35915802 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33728385 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34173157 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 35810173 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 34388099 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 34388099 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34882964 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 32398119 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32398119 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 32487077 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 32677716 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 35227647 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 34580379 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34580379 — Predictive Biomarker (PRD): APEX1 mRNA
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 33795257 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33795257 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 33795257 — Predictive Biomarker (PRD): ATRX mRNA
Genes: ATRX; RAD54L; XH2
Study 34399547 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 32144166 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 35582785 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 34695552 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 32988969 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 32988969 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32988969 — Predictive Biomarker (PRD): Hormone receptor
Study 33983107 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33983107 — Safety Biomarker (SAF): BDNF
Study 34337526 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 34337526 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 34337526 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 35894919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35894919 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 35894919 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 35988193 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32421854 — Predictive Biomarker (PRD): CYP51A1 mRNA
Genes: CYP51A1; CYP51
Study 33754923 — Surrogate Endpoint (SUR): Blood pressure
Study 33413593 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 34542204 — Surrogate Endpoint (SUR): Blood pressure
Study 34542204 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35527689 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 33607792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34341035 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34341035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32182226 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33660345 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 32151735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35621073 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 35621073 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 35621073 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32320797 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35760720 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 35760720 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35869634 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 35880279 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 32597548 — Surrogate Endpoint (SUR): Serum creatinine
Study 32597548 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32962406 — Predictive Biomarker (PRD): DUSP2 mRNA
Genes: DUSP2; PAC1
Study 36410210 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 32513495 — Surrogate Endpoint (SUR): Bone mineral density
Study 32495521 — Surrogate Endpoint (SUR): Serum calcium
Study 32495521 — Surrogate Endpoint (SUR): Bone mineral density
Study 34213471 — Surrogate Endpoint (SUR): Blood pressure
Study 34213471 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33775198 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34823545 — Predictive Biomarker (PRD): NFIC mRNA
Genes: NFIC; NFI
Study 33710588 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 35883392 — Safety Biomarker (SAF): Hyaluronic acid
Study 33181788 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35190442 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35190442 — Surrogate Endpoint (SUR): Blood pressure
Study 32147072 — Surrogate Endpoint (SUR): Blood pressure
Study 33411130 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 35166922 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 34866234 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34866234 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 36894736 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 35182247 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36210517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33396852 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 36154950 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 35654374 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35654374 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 35654374 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study 35654374 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 35654374 — Predictive Biomarker (PRD): BARD1 mRNA
Genes: BARD1
Study 35654374 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study 35654374 — Predictive Biomarker (PRD): RAD51C mRNA
Genes: RAD51C; RAD51L2
Study 32453368 — Surrogate Endpoint (SUR): Blood pressure
Study 36158122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36158122 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33638926 — Safety Biomarker (SAF): Hyaluronic acid
Study 33060043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33060043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32127890 — Surrogate Endpoint (SUR): Blood pressure
Study 34508557 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 34871513 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34119655 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 35000582 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 36451616 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 33725465 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 33725465 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36188104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34107031 — Surrogate Endpoint (SUR): Blood pressure
Study 32755427 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33742561 — Surrogate Endpoint (SUR): Blood pressure
Study 32186960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35232809 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 35232809 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 32656706 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32303700 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study 33563233 — Predictive Biomarker (PRD): Protein patched homolog 1
Genes: PTCH1; PTCH
Study 32470635 — Predictive Biomarker (PRD): IVL mRNA
Genes: IVL
Study 34273680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34766228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34766228 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 34766228 — Safety Biomarker (SAF): Interleukin 1
Study 34115106 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33729391 — Surrogate Endpoint (SUR): Blood pressure
Study 35410334 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32417770 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 35048316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35048316 — Surrogate Endpoint (SUR): Blood pressure
Study 33399382 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 32680465 — Predictive Biomarker (PRD): GNS mRNA
Genes: GNS
Study 34005830 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 32161453 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32161453 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34793687 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34793687 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 35525389 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 34348260 — Surrogate Endpoint (SUR): Serum sodium
Study 33964166 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 34326841 — Predictive Biomarker (PRD): TRPM3 mRNA
Genes: TRPM3; KIAA1616; LTRPC3
Study 36476322 — Surrogate Endpoint (SUR): Blood pressure
Study 36474100 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 35873384 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 35873384 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 34803424 — Surrogate Endpoint (SUR): Blood pressure
Study 33907786 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 33907786 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 32822287 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32822287 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32822287 — Predictive Biomarker (PRD): Hormone receptor
Study 32438783 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32438783 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32310854 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33460256 — Surrogate Endpoint (SUR): Blood pressure
Study 34081137 — Surrogate Endpoint (SUR): Blood pressure
Study 35289183 — Predictive Biomarker (PRD): SDC1 mRNA
Genes: SDC1; SDC
Study 35289183 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35289183 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35289183 — Safety Biomarker (SAF): Hyaluronic acid
Study 35289183 — Safety Biomarker (SAF): Reactive oxygen species
Study 34793552 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32792712 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 32376812 — Surrogate Endpoint (SUR): Blood pressure
Study 34828790 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 33386149 — Predictive Biomarker (PRD): BACH2 mRNA
Genes: BACH2
Study 33386149 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 33386149 — Predictive Biomarker (PRD): MX1 mRNA
Genes: MX1
Study 33386149 — Predictive Biomarker (PRD): SYNGR1 mRNA
Genes: SYNGR1
Study 34649864 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35426903 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 36318788 — Surrogate Endpoint (SUR): Blood pressure
Study 34312872 — Surrogate Endpoint (SUR): Probing pocket depth
Study 35192411 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 33522954 — Surrogate Endpoint (SUR): Blood pressure
Study 32727497 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 35314388 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32773581 — Surrogate Endpoint (SUR): Blood pressure
Study 35852582 — Surrogate Endpoint (SUR): Blood pressure
Study 32326796 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 33512618 — Surrogate Endpoint (SUR): Blood pressure
Study 33243806 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35854255 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33589633 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 35958552 — Predictive Biomarker (PRD): CNTN1 mRNA
Genes: CNTN1
Study 35958552 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 34916086 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33931919 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 35469481 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 35409444 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 33583149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33583149 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 33631357 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33631357 — Surrogate Endpoint (SUR): Blood pressure
Study 32386421 — Surrogate Endpoint (SUR): Blood pressure
Study 33879077 — Predictive Biomarker (PRD): DGKE mRNA
Genes: DGKE; DAGK5
Study 33879077 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 33879077 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 33012286 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33012286 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 33012286 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35241817 — Surrogate Endpoint (SUR): Blood pressure
Study 33436973 — Surrogate Endpoint (SUR): Bone mineral density
Study 35059825 — Predictive Biomarker (PRD): LHB mRNA
Genes: LHB
Study 35197363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33331859 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33331859 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32699404 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33279389 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32050789 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 35190895 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 35190895 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 34154951 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 33972313 — Surrogate Endpoint (SUR): Blood pressure
Study 33411640 — Surrogate Endpoint (SUR): Blood pressure
Study 35040869 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 34462881 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 33057367 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 33057367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33852200 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 32590148 — Surrogate Endpoint (SUR): Blood pressure
Study 34819273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36428216 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 35352277 — Surrogate Endpoint (SUR): Blood pressure
Study 32932174 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35508201 — Surrogate Endpoint (SUR): Blood pressure
Study 35508300 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32546273 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 36322258 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33200660 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 33089454 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32347768 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32747417 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 32747417 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32747417 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 32747417 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 34052947 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 33186740 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 33186740 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33186740 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 33186740 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 36370124 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study 36370124 — Predictive Biomarker (PRD): CA2 mRNA
Genes: CA2
Study 33972742 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 33471486 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 34003685 — Surrogate Endpoint (SUR): Blood pressure
Study 35654863 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33157048 — Predictive Biomarker (PRD): KDM5C mRNA
Genes: KDM5C; DXS1272E; JARID1C; SMCX; XE169
Study 33157048 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 33157048 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 33157048 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33454354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33454354 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33984886 — Predictive Biomarker (PRD): SGCA mRNA
Genes: SGCA; ADL; DAG2
Study 36045304 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 36194181 — Monitoring Biomarker (MOI): HBV DNA
Study 34593120 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 34593120 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 34593120 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 34273682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32248829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34237274 — Predictive Biomarker (PRD): PRC1 mRNA
Genes: PRC1
Study 34933532 — Surrogate Endpoint (SUR): Sperm parameters
Study 34933532 — Safety Biomarker (SAF): Reactive oxygen species
Study 34677153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34677153 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34677153 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35760666 — Safety Biomarker (SAF): Hyaluronic acid
Study 35246416 — Surrogate Endpoint (SUR): Blood pressure
Study 32314464 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 36445874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35594564 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34980546 — Surrogate Endpoint (SUR): Bone mineral density
Study 33990969 — Predictive Biomarker (PRD): KDM1A mRNA
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study 35231887 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 33704919 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 33135866 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33135866 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32329651 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 32329651 — Predictive Biomarker (PRD): NTRK