TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04432337 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT05559879 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05314569 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT05878561 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06407362 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05205707 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT05205707 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04706546 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT06528262 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06528262 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT06144814 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06468774 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study NCT05993975 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04759911 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT05569577 — Predictive Biomarker (PRD): IHH mRNA
Genes: IHH
Study NCT06508567 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06671691 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT06671691 — Predictive Biomarker (PRD): PPP3R1 mRNA
Genes: PPP3R1; CNA2; CNB
Study NCT06671691 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06671912 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06672523 — Predictive Biomarker (PRD): MTAP mRNA
Genes: MTAP; MSAP
Study NCT05896293 — Predictive Biomarker (PRD): IHH mRNA
Genes: IHH
Study NCT04872985 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04872985 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04872985 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study NCT04872985 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05060107 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04671680 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05761327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05761327 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06235242 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT05814601 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02473653 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05480774 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05409820 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05760118 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06302738 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04102891 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study NCT04102891 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT04102891 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05580510 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT00106834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04735796 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT05050500 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05723640 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT06151015 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06151015 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT05461690 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT05447962 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04487756 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04652258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06302634 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06510465 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05115201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06483633 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06296810 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT06735625 — Predictive Biomarker (PRD): AHSP mRNA
Genes: AHSP; EDRF; ERAF
Study NCT06128941 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT05468736 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05590546 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05602467 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06255977 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT05024318 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05276960 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT05276960 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05119686 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT05087823 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05087823 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT04530825 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05592834 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT05386433 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04526977 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04526977 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04526977 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT05472454 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06256120 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06256120 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT05420012 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study NCT05420012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06344780 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06344780 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06561971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05657977 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study NCT05385705 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05385705 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05111249 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT06274489 — Predictive Biomarker (PRD): NOX1 mRNA
Genes: NOX1; MOX1; NOH1
Study NCT06098846 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT06232486 — Surrogate Endpoint (SUR): Serum calcium
Study NCT06168955 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05640986 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT05869682 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT05619913 — Predictive Biomarker (PRD): HMGA2 mRNA
Genes: HMGA2; HMGIC
Study NCT05990998 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05462587 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT05462587 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study NCT04743518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06074601 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study NCT06272253 — Surrogate Endpoint (SUR): Neutralizing antibody response
Study NCT06272253 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05025488 — Predictive Biomarker (PRD): CALR mRNA
Genes: CALR; CRTC
Study NCT06485544 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT06278909 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT05376202 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05376202 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05673135 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04996576 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05652660 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT04770155 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT04918472 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT06273865 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT06273865 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT06273865 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT06400017 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05789108 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06468410 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06012604 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05429684 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05429684 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01561092 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study NCT05418660 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05418660 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00002178 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05171530 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05425251 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT06398795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05660083 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05660083 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT05022264 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05132790 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05132790 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05132790 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06556810 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT06668103 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06668103 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05690763 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study NCT05512364 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05669248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04716114 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05603663 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06336759 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06229366 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06091787 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT06091787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06091787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06091787 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT06605378 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00000664 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05041387 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06743659 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT06047171 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT06358118 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06358118 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06358118 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04146298 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04146298 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT05760976 — Surrogate Endpoint (SUR): Serum potassium
Study NCT00000681 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05717738 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06611631 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06672263 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT06672263 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT06672692 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06673394 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT06673394 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT06673394 — Predictive Biomarker (PRD): Anti-aquaporin-4 antibody
Study NCT06522347 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT06768151 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT05170308 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study NCT06767241 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06767241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06633302 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06547112 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05409885 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT05409885 — Safety Biomarker (SAF): Platelet to lymphocyte
Study NCT04964167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06767800 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06543082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04884776 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05885685 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study NCT04448249 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06256627 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT06318442 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT06440083 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05583786 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06325709 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study NCT04807153 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06512220 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study NCT04704336 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05120271 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT04932733 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05863156 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04692493 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06165224 — Predictive Biomarker (PRD): COMMD10 mRNA
Genes: COMMD10; HSPC305; PTD002
Study NCT05662358 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06091800 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06091800 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study NCT05279118 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT05705583 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05705583 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06188676 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06337227 — Predictive Biomarker (PRD): SIRT6 mRNA
Genes: SIRT6; SIR2L6
Study NCT05472610 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05675982 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05675982 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00934258 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT05898503 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05898503 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05898503 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05898503 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05898503 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05898503 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT05020184 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study NCT06522412 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT06522412 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05745090 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT05745090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05250752 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT00001089 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06390137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05182203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05116085 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04671797 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT06065956 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06622889 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06710106 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT06710106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06710106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06710106 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT06703190 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04740203 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04740203 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT06739330 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT00002443 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06745726 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05621460 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05713006 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06128512 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06088381 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06482918 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05151744 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05151744 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06547840 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT06290583 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06319560 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06377358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06377358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06377358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05267574 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT04822922 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT06123403 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT05086939 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05022992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05022992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05022992 — Safety Biomarker (SAF): Interleukin 1
Study NCT06065384 — Pharmacodynamic Biomarker (PDY): Nerve excitability testing
Study NCT05187338 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT05187338 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05187338 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06348134 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05930951 — Predictive Biomarker (PRD): LY75 mRNA
Genes: LY75; CD205; CLEC13B