TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05215951 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05760651 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06325644 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study NCT05609513 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05352230 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03482245 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04748107 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06048913 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06075680 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT06075680 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study NCT05592145 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06399835 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06399835 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT06399835 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06399835 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04905836 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04905836 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06190392 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT06512753 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study NCT04941079 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05430373 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT05430373 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05510037 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06446050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06446050 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05990829 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05990829 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06582511 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study NCT06582004 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT05370625 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05460338 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT05460338 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT05460338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05460338 — Surrogate Endpoint (SUR): Serum calcium
Study NCT05460338 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT03066661 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT03066661 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03066661 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT06401135 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study NCT05346198 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT05346198 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05870813 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05870813 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05164770 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04420845 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05984199 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT05362071 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06482138 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00000756 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05021900 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT05762081 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05116501 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT05116501 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT05257668 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06439485 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT05312736 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study NCT04460872 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05869955 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04688450 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06787742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06789705 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT06789198 — Predictive Biomarker (PRD): DNAJB1 mRNA
Genes: DNAJB1; DNAJ1; HDJ1; HSPF1
Study NCT06789198 — Predictive Biomarker (PRD): PRKACA mRNA
Genes: PRKACA; PKACA
Study NCT06056102 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06056102 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05673200 — Safety Biomarker (SAF): CDA
Genes: CDD
Study NCT06534125 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06534125 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06354881 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00000914 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06047119 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05133531 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT05519475 — Predictive Biomarker (PRD): HSD17B13 mRNA
Genes: HSD17B13; SCDR9; SDR16C3; HMFN0376; UNQ497/PRO1014
Study NCT05136664 — Surrogate Endpoint (SUR): Serum potassium
Study NCT06313398 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05843786 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT06388954 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06388954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05882344 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06588660 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT06788990 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06788990 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05684874 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT05667090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05667090 — Surrogate Endpoint (SUR): Serum calcium
Study NCT05110742 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study NCT05110742 — Predictive Biomarker (PRD): IL15 mRNA
Genes: IL15
Study NCT05622708 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06551324 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT06790680 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT06785480 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06785480 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study NCT06787222 — Safety Biomarker (SAF): Interleukin 1
Study NCT06782542 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT06789679 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT06782490 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study NCT06782490 — Predictive Biomarker (PRD): MGLL mRNA
Genes: MGLL
Study NCT05761899 — Predictive Biomarker (PRD): CSF2RA mRNA
Genes: CSF2RA; CSF2R; CSF2RY
Study NCT05761899 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05650112 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT03613181 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04899180 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT05281510 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study NCT05913583 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06068842 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05628597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05043480 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05421416 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05642871 — Predictive Biomarker (PRD): XRCC2 mRNA
Genes: XRCC2
Study NCT05566899 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT04945460 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT04945460 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT04703153 — Predictive Biomarker (PRD): UBXN11 mRNA
Genes: UBXN11; SOC; UBXD5; PP2243
Study NCT05413317 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT05601219 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT05642247 — Safety Biomarker (SAF): Interleukin 12
Study NCT03945305 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05354037 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT04842331 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06136741 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05236725 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06531109 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study NCT06008756 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT05735730 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05969184 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05969184 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06447532 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06447532 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06447532 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06447532 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05418842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05712083 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05127590 — Predictive Biomarker (PRD): TIPARP mRNA
Genes: TIPARP; PARP7
Study NCT05798975 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05798975 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06790810 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05012397 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT05012397 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT06790225 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT06790225 — Predictive Biomarker (PRD): GIPR mRNA
Genes: GIPR
Study NCT06792266 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT06792266 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT06792266 — Safety Biomarker (SAF): miR-375
Genes: MIR375
Study NCT06510699 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT06288451 — Surrogate Endpoint (SUR): Serum calcium
Study NCT06288451 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT05553821 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT06792435 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT06783049 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06784752 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT04678518 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04678518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04678518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04514692 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT04514692 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06575634 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06459947 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study NCT04911517 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04911517 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05188313 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05410249 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT05410249 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT05029817 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT06329570 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT06129448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06795022 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT06310720 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06793774 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study NCT06792812 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study NCT06301438 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06301438 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06793735 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06794996 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study NCT06797817 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06797817 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT06796634 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study NCT06525350 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05605418 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06209580 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study NCT05307874 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT06796114 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06796114 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT06796114 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06796114 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06794502 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT06794502 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT05265286 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT06794008 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06794008 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05541367 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06578299 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06792838 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT06795646 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06795646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06796712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06794281 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06794281 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study NCT06506916 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIPOX mRNA
Genes: PIPOX; LPIPOX; PSO
Study NCT01333592 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT05908877 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06463990 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04341363 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT06797713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05988827 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT06793449 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06797336 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04504968 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06795152 — Predictive Biomarker (PRD): PRKAG2 mRNA
Genes: PRKAG2
Study NCT06793332 — Predictive Biomarker (PRD): TACSTD2 mRNA
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study NCT06794593 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06795178 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT04713605 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05052957 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT06797193 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05972993 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05831878 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06140537 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06797622 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04395456 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT06451757 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT05382208 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06796647 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT06010953 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT06796920 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study NCT06065163 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06796660 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT06797362 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT06794372 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT04520217 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study NCT06797206 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT06797518 — Predictive Biomarker (PRD): MEST mRNA
Genes: MEST; PEG1
Study NCT06797518 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT06794736 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT06794736 — Predictive Biomarker (PRD): ATRX mRNA
Genes: ATRX; RAD54L; XH2
Study NCT06794736 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT06793345 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06793930 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06797635 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06797635 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06797635 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06797635 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05774067 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05973539 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05973539 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06794814 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study NCT06795581 — Predictive Biomarker (PRD): PDE4B mRNA
Genes: PDE4B; DPDE4
Study NCT05962723 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04571970 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study NCT06796075 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06796283 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT06795191 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT05801705 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05801705 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06793241 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06792799 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06792799 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05790395 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05259332 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT06794853 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT06634589 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT06636227 — Predictive Biomarker (PRD): KMO mRNA
Genes: KMO
Study NCT06015724 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT06015724 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06015724 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06797401 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05348759 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT06793787 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study NCT06793787 — Predictive Biomarker (PRD): TCP1 mRNA
Genes: TCP1; CCT1; CCTA
Study NCT06793787 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study NCT06233864 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06795399 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT05421819 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06793085 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05646862 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05646862 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA