TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT06098560 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05683327 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06326502 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT06326502 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT06326502 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT06326502 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04676399 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06525246 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05393505 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05800145 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06496074 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04601038 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study NCT05123677 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study NCT05889390 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04713514 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05222542 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05222542 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT05880121 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06126965 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT05494541 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05506358 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study NCT04761614 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04761614 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05143151 — Predictive Biomarker (PRD): CD276 mRNA
Genes: CD276; B7H3; PSEC0249; UNQ309/PRO352
Study NCT06128551 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06401005 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT06038708 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05336110 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05920005 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05507450 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05234021 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06406140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06406140 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06406140 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04942054 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04942054 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04942054 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04942054 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04942054 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06199713 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05913440 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05913440 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05365841 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT04665206 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT05636163 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT05636163 — Safety Biomarker (SAF): Platelet to lymphocyte
Study NCT04946565 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT04926168 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00000106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05558995 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study NCT05558995 — Safety Biomarker (SAF): BDNF
Study NCT06303713 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05963191 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study NCT05963191 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study NCT06070974 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study NCT06429839 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06649344 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06401993 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study NCT05438732 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT06063850 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study NCT05474664 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT05709483 — Predictive Biomarker (PRD): F2RL3 mRNA
Genes: F2RL3; PAR4
Study NCT06296654 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06088849 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05418231 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05395208 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06206083 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT06206083 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study NCT06206083 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study NCT06206083 — Predictive Biomarker (PRD): MSH3 mRNA
Genes: MSH3; DUC1; DUG
Study NCT06206083 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT05861635 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05253924 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study NCT05253924 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study NCT05253924 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study NCT05253924 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT05253924 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study NCT06225557 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT06412588 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT00000651 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05329298 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study NCT05366465 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT04705090 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT05667350 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05946798 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT05380531 — Predictive Biomarker (PRD): CTSA mRNA
Genes: CTSA; PPGB
Study NCT05703243 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT04274023 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study NCT04673617 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06426654 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04751292 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04232631 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06140290 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05632341 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05397548 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04696315 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06055036 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06139393 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT05125380 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT06221553 — Predictive Biomarker (PRD): CD276 mRNA
Genes: CD276; B7H3; PSEC0249; UNQ309/PRO352
Study NCT06406543 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT04963595 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04963595 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05784116 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT06141824 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06169241 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05440032 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05806047 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05806047 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05806047 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05018520 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT05046665 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT05114837 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06276088 — Predictive Biomarker (PRD): SAA1 mRNA
Genes: SAA1
Study NCT02937376 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT04802707 — Predictive Biomarker (PRD): RRM2B mRNA
Genes: RRM2B; P53R2
Study NCT04802707 — Predictive Biomarker (PRD): MPV17 mRNA
Genes: MPV17
Study NCT04802707 — Predictive Biomarker (PRD): SUCLA2 mRNA
Genes: SUCLA2
Study NCT04802707 — Predictive Biomarker (PRD): SUCLG1 mRNA
Genes: SUCLG1
Study NCT04802707 — Predictive Biomarker (PRD): FBXL4 mRNA
Genes: FBXL4; FBL4; FBL5
Study NCT04802707 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT04989010 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT04883970 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT04610775 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05000970 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05722795 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06313645 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT04823962 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05456711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05328505 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05507762 — Monitoring Biomarker (MOI): HBV DNA
Study NCT06383871 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05387174 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05502523 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05935293 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05403138 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT05403138 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT05403138 — Predictive Biomarker (PRD): Anti-aquaporin-4 antibody
Study NCT05507593 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study NCT05397418 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05476107 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study NCT04555681 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT05417698 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05705401 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05662813 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00002321 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05364996 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT05215080 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT06394674 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05192642 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT05192642 — Predictive Biomarker (PRD): NTRK
Study NCT05278897 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05724290 — Predictive Biomarker (PRD): EGR2 mRNA
Genes: EGR2; KROX20
Study NCT05724290 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-150
Genes: MIR150
Study NCT04726293 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05834764 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05953857 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT04184661 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT04184661 — Predictive Biomarker (PRD): DMP1 mRNA
Genes: DMP1
Study NCT04184661 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study NCT06002971 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04589611 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04844866 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT04886596 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03555552 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT06351176 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04900311 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06457399 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05342571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05696795 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT05771675 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT06110728 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05167747 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05239702 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT06401291 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05054218 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05964192 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study NCT05964192 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study NCT05378503 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00001045 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06133075 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04897152 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05255926 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT06307782 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05756439 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04979832 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06629480 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05512208 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT05512208 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study NCT06227156 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06000917 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06054841 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06652984 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05979363 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05855317 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT06447636 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT06447636 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study NCT06447636 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT05178056 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05613348 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05895110 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05552534 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT05493566 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04347772 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT06235554 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06285968 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05884242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05446025 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT05970445 — Predictive Biomarker (PRD): SLC26A4 mRNA
Genes: SLC26A4; PDS
Study NCT06115460 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT06115460 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT06141161 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study NCT05228821 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05355766 — Predictive Biomarker (PRD): Liver iron
Study NCT06173284 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT06417138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06426199 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06174870 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06389786 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05070637 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT05220423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06622499 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04884867 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05592392 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study NCT05934240 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06425315 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT06425315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06705530 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05249530 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00545207 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06366789 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT06095141 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT04768166 — Predictive Biomarker (PRD): SPG11 mRNA
Genes: SPG11; KIAA1840
Study NCT04329065 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04722159 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06299852 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06712771 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study NCT06708429 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study NCT06708429 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study NCT05808153 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT05726175 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06030141 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT06030141 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT05059548 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study NCT06712485 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04637945 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT05408312 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05876455 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT04780841 — Surrogate Endpoint (SUR): Serum potassium
Study NCT05955209 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06467773 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT06295328 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04992247 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT06476366 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study NCT05989724 — Predictive Biomarker (PRD): SON mRNA
Genes: SON; C21orf50; DBP5; KIAA1019; NREBP; HSPC310; HSPC312
Study NCT06714591 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT06219486 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT06713720 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06713720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05991830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05991830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01261286 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06064292 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT06258759 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06713525 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT05509153 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT06265311 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05743881 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06138587 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04997941 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT06187493 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06028841 — Surrogate Endpoint (SUR): Neutralizing antibody