TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33170484 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 33170593 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 33170593 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 33170593 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33171854 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 33173161 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33173916 — Surrogate Endpoint (SUR): Blood pressure
Study 33174479 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 33174479 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study 33174479 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 33175262 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33175911 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 33176736 — Surrogate Endpoint (SUR): Blood pressure
Study 33176736 — Surrogate Endpoint (SUR): Serum creatinine
Study 33177139 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 33177142 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 33177997 — Surrogate Endpoint (SUR): Blood pressure
Study 33178207 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 33178408 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 33178408 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33178636 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 33178636 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study 33180106 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 33180106 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 33180905 — Surrogate Endpoint (SUR): Blood pressure
Study 33181648 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 33183322 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 33184050 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33184050 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 33184050 — Safety Biomarker (SAF): PPOX
Genes: HCRT; OX
Study 33186471 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 33186471 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33186471 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 33186471 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 33186471 — Predictive Biomarker (PRD): SMAD4 mRNA
Genes: SMAD4; DPC4; MADH4
Study 33186471 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33186471 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study 33186471 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 33186471 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 33187477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33188140 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 33188997 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 33188997 — Predictive Biomarker (PRD): CREBBP mRNA
Genes: CREBBP; CBP
Study 33188997 — Predictive Biomarker (PRD): KMT2D mRNA
Genes: KMT2D; ALR; MLL2; MLL4
Study 33188997 — Predictive Biomarker (PRD): LRP1B mRNA
Genes: LRP1B; LRPDIT
Study 33188997 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 33188997 — Predictive Biomarker (PRD): TNFRSF14 mRNA
Genes: TNFRSF14; HVEA; HVEM; UNQ329/PRO509
Study 33188997 — Predictive Biomarker (PRD): CD79B mRNA
Genes: CD79B; B29; IGB
Study 33189632 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 33189854 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 33190086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33190086 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33190086 — Safety Biomarker (SAF): IL-6 and IL-10
Study 33191169 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 33191282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33191407 — Predictive Biomarker (PRD): MACROD2 mRNA
Genes: MACROD2; C20orf133
Study 33191407 — Predictive Biomarker (PRD): MIPOL1 mRNA
Genes: MIPOL1
Study 33191407 — Predictive Biomarker (PRD): TTC6 mRNA
Genes: TTC6; C14orf25; NCRNA00291
Study 33191407 — Predictive Biomarker (PRD): TP63 mRNA
Genes: TP63; KET; P63; P73H; P73L; TP73L
Study 33191407 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 33191407 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study 33193314 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 33193314 — Predictive Biomarker (PRD): C9 mRNA
Genes: C9
Study 33193314 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33193314 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 33194741 — Predictive Biomarker (PRD): CYP26A1 mRNA
Genes: CYP26A1; CYP26; P450RAI1
Study 33195874 — Predictive Biomarker (PRD): GREM1 mRNA
Genes: GREM1; CKTSF1B1; DAND2; DRM; PIG2
Study 33196448 — Surrogate Endpoint (SUR): Blood pressure
Study 33196581 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 33197289 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33197293 — Surrogate Endpoint (SUR): Blood pressure
Study 33197925 — Predictive Biomarker (PRD): GSPT1 mRNA
Genes: GSPT1; ERF3A
Study 33197925 — Predictive Biomarker (PRD): ILF2 mRNA
Genes: ILF2; NF45; PRO3063
Study 33197925 — Predictive Biomarker (PRD): ILF3 mRNA
Genes: ILF3; DRBF; MPHOSPH4; NF90
Study 33197925 — Predictive Biomarker (PRD): ATF4 mRNA
Genes: ATF4; CREB2; TXREB
Study 33198571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33198671 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33198671 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33198671 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 33198781 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33199155 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 33199247 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 33199511 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33199917 — Surrogate Endpoint (SUR): Blood pressure
Study 33200890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33200890 — Safety Biomarker (SAF): Interleukin 1
Study 33201358 — Predictive Biomarker (PRD): Hormone receptor
Study 33201788 — Predictive Biomarker (PRD): AZIN2 mRNA
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 33201924 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 33201924 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 33201924 — Surrogate Endpoint (SUR): Serum creatinine
Study 33203626 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33203644 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 33203723 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 33204013 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 33204013 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 33205032 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33205032 — Surrogate Endpoint (SUR): Pathological complete response
Study 33205280 — Predictive Biomarker (PRD): C9 mRNA
Genes: C9
Study 33205510 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 33205510 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 33206392 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33206936 — Predictive Biomarker (PRD): PTPRD mRNA
Genes: PTPRD
Study 33206936 — Predictive Biomarker (PRD): TRAF3 mRNA
Genes: TRAF3; CAP-1; CRAF1; TRAFAMN
Study 33206936 — Predictive Biomarker (PRD): BTG2 mRNA
Genes: BTG2; PC3
Study 33206936 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 33206936 — Predictive Biomarker (PRD): NFATC1 mRNA
Genes: NFATC1; NFAT2; NFATC
Study 33206936 — Predictive Biomarker (PRD): PAX5 mRNA
Genes: PAX5
Study 33206936 — Predictive Biomarker (PRD): SLC44A5 mRNA
Genes: SLC44A5; CTL5
Study 33206936 — Predictive Biomarker (PRD): FCRL3 mRNA
Genes: FCRL3; FCRH3; IFGP3; IRTA3; SPAP2
Study 33206936 — Predictive Biomarker (PRD): SELL mRNA
Genes: SELL; LNHR; LYAM1
Study 33206936 — Predictive Biomarker (PRD): TNIP2 mRNA
Genes: TNIP2; ABIN2; FLIP1
Study 33207078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33208090 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 33208158 — Predictive Biomarker (PRD): ADAM22 mRNA
Genes: ADAM22; MDC2
Study 33208158 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study 33208914 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study 33209056 — Surrogate Endpoint (SUR): Blood pressure
Study 33210276 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33211315 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 33211315 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 33211315 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 33211842 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 33213832 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 33213866 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 33216280 — Predictive Biomarker (PRD): PAX4 mRNA
Genes: PAX4
Study 33216879 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33216879 — Surrogate Endpoint (SUR): Blood pressure
Study 33217027 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 33219092 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33219145 — Predictive Biomarker (PRD): GNE mRNA
Genes: GNE; GLCNE
Study 33220319 — Surrogate Endpoint (SUR): Blood pressure
Study 33221175 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 33221715 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33221921 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 33222307 — Predictive Biomarker (PRD): TAS1R3 mRNA
Genes: TAS1R3; T1R3; TR3
Study 33222617 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33224628 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 33225383 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33225717 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 33227457 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 33228537 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 33228771 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 33228797 — Predictive Biomarker (PRD): NPC1 mRNA
Genes: NPC1
Study 33228797 — Predictive Biomarker (PRD): NPC2 mRNA
Genes: NPC2; HE1
Study 33228978 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 33229362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33229362 — Safety Biomarker (SAF): Interleukin 1
Study 33229456 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 33229508 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33229508 — Predictive Biomarker (PRD): ARHGEF5 mRNA
Genes: ARHGEF5; TIM
Study 33229508 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 33230103 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 33230962 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 33231487 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33232306 — Predictive Biomarker (PRD): MAGEL2 mRNA
Genes: MAGEL2; NDNL1
Study 33232483 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 33234651 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33235353 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 33235733 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33236084 — Surrogate Endpoint (SUR): Bone mineral density
Study 33237291 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33239013 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 33239386 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 33239440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-34a
Genes: MIR34A
Study 33239440 — Predictive Biomarker (PRD): miR-345
Genes: MIR345
Study 33239440 — Safety Biomarker (SAF): miR-200c
Genes: MIR200C
Study 33239440 — Safety Biomarker (SAF): miR-10a
Genes: MIR10A
Study 33239737 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33240077 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 33240315 — Monitoring Biomarker (MOI): Cell-free DNA
Study 33242065 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 33242441 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 33242536 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 33242536 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study 33242536 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33242662 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study 33243251 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 33244458 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33246099 — Surrogate Endpoint (SUR): Blood pressure
Study 33246438 — Predictive Biomarker (PRD): UBXN11 mRNA
Genes: UBXN11; SOC; UBXD5; PP2243
Study 33246589 — Surrogate Endpoint (SUR): Blood pressure
Study 33246973 — Predictive Biomarker (PRD): TK2 mRNA
Genes: TK2
Study 33246973 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 33246973 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33247178 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 33247178 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33248962 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33248962 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 33249510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33249569 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 33249636 — Predictive Biomarker (PRD): LRP1 mRNA
Genes: LRP1; A2MR; APR
Study 33249636 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 33249636 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 33249802 — Predictive Biomarker (PRD): UST mRNA
Genes: UST; DS2ST
Study 33252547 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study 33252834 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 33252834 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 33253089 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33253198 — Predictive Biomarker (PRD): RPIA mRNA
Genes: RPIA; RPI
Study 33253692 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 33255658 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33256377 — Surrogate Endpoint (SUR): Hematologic response
Study 33256829 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33256829 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33257488 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33257977 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 33257977 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 33258568 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33258745 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33258950 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 33258950 — Surrogate Endpoint (SUR): Bone mineral density
Study 33259448 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 33259589 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 33259589 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 33259589 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 33259589 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 33259589 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33259596 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 33259932 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33259932 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33261814 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 33261814 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 33261814 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33262134 — Predictive Biomarker (PRD): MSLN mRNA
Genes: MSLN; MPF
Study 33262134 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33262580 — Surrogate Endpoint (SUR): Blood pressure
Study 33264183 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33264515 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33267723 — Surrogate Endpoint (SUR): Blood pressure
Study 33268442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33268442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33269549 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33270471 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 33270816 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study 33270816 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 33270832 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 33270832 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 33270832 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 33270906 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 33272982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33273214 — Surrogate Endpoint (SUR): Bone mineral density
Study 33273214 — Monitoring Biomarker (MOI): HBV DNA
Study 33273485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33274416 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33274751 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 33276318 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33276423 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33277223 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33277223 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 33277223 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33277290 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 33277427 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 33277427 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 33277427 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 33277427 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 33278016 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33278125 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 33278656 — Surrogate Endpoint (SUR): Bone mineral density
Study 33280027 — Surrogate Endpoint (SUR): Serum potassium
Study 33280228 — Surrogate Endpoint (SUR): Blood pressure
Study 33281950 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33281950 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33281950 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 33281950 — Predictive Biomarker (PRD): Hormone receptor
Study 33282388 — Surrogate Endpoint (SUR): Pathological complete response
Study 33283989 — Predictive Biomarker (PRD): BCL11A mRNA
Genes: BCL11A; CTIP1; EVI9; KIAA1809; ZNF856
Study 33283989 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 33283990 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 33283990 — Predictive Biomarker (PRD): BCL11A mRNA
Genes: BCL11A; CTIP1; EVI9; KIAA1809; ZNF856
Study 33284467 — Predictive Biomarker (PRD): LAMB2 mRNA
Genes: LAMB2; LAMS
Study 33284683 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33284946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33287189 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 33287704 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 33287722 — Monitoring Biomarker (MOI): HBV DNA
Study 33288587 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5