TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35585981 — Predictive Biomarker (PRD): CXCL2 mRNA
Genes: CXCL2; GRO2; GROB; MIP2A; SCYB2
Study 35585981 — Predictive Biomarker (PRD): KLF4 mRNA
Genes: KLF4; EZF; GKLF
Study 36976583 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 35138402 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33792832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35994126 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 35994126 — Surrogate Endpoint (SUR): Probing pocket depth
Study 35403296 — Predictive Biomarker (PRD): GCLC mRNA
Genes: GCLC; GLCL; GLCLC
Study 35403296 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 32977846 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33843831 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 32183861 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32000598 — Safety Biomarker (SAF): Hyaluronic acid
Study 34500117 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 35122992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32683565 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32683565 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 32683565 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32683565 — Predictive Biomarker (PRD): Hormone receptor
Study 32683565 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35856373 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 33484699 — Surrogate Endpoint (SUR): Serum creatinine
Study 33484699 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 33484699 — Surrogate Endpoint (SUR): Blood pressure
Study 36067151 — Surrogate Endpoint (SUR): Blood pressure
Study 34230975 — Safety Biomarker (SAF): Hyaluronic acid
Study 32193660 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32193660 — Surrogate Endpoint (SUR): Blood pressure
Study 33711814 — Surrogate Endpoint (SUR): Blood pressure
Study 36075591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33206228 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33556040 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 36263703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36263703 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 36261050 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 34618684 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 34127491 — Surrogate Endpoint (SUR): Blood pressure
Study 36068106 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33184089 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 35987681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33482893 — Surrogate Endpoint (SUR): Blood pressure
Study 32197407 — Surrogate Endpoint (SUR): Blood pressure
Study 32197407 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32070401 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32070401 — Predictive Biomarker (PRD): Hormone receptor
Study 32070401 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34569489 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 32662228 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 32415945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32415945 — Monitoring Biomarker (MOI): Procalcitonin
Study 33658605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33658605 — Predictive Biomarker (PRD): FADD mRNA
Genes: FADD; MORT1; GIG3
Study 33658605 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 33658605 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 33658605 — Safety Biomarker (SAF): c-Jun N-terminal kinase
Study 32560689 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 34529043 — Predictive Biomarker (PRD): SCAI mRNA
Genes: SCAI; C9orf126
Study 35222584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35222584 — Safety Biomarker (SAF): IL-6 and IL-10
Study 32006099 — Surrogate Endpoint (SUR): Blood pressure
Study 34842924 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34473215 — Surrogate Endpoint (SUR): Serum calcium
Study 33653406 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 32130172 — Surrogate Endpoint (SUR): Blood pressure
Study 35863812 — Surrogate Endpoint (SUR): Blood pressure
Study 32794404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 32348036 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 32348036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 32472880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35366640 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32344167 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35775679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35775679 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32754804 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 32754804 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 32081240 — Surrogate Endpoint (SUR): Blood pressure
Study 34665453 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 34665453 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 34190055 — Predictive Biomarker (PRD): WNT16 mRNA
Genes: WNT16
Study 34190055 — Surrogate Endpoint (SUR): Bone mineral density
Study 34626918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34808104 — Surrogate Endpoint (SUR): Blood pressure
Study 34808104 — Surrogate Endpoint (SUR): Serum potassium
Study 33568079 — Surrogate Endpoint (SUR): Blood pressure
Study 34746999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32816629 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35839921 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35839921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33985942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35451678 — Surrogate Endpoint (SUR): Blood pressure
Study 33519434 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35766954 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 35766954 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35005205 — Surrogate Endpoint (SUR): Blood pressure
Study 33038262 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 34878549 — Surrogate Endpoint (SUR): Blood pressure
Study 35099133 — Predictive Biomarker (PRD): DCT mRNA
Genes: DCT; TYRP2
Study 33213378 — Surrogate Endpoint (SUR): Serum sodium
Study 35732345 — Surrogate Endpoint (SUR): Serum uric acid
Study 32475360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32991046 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 32991046 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 35578304 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 35679098 — Surrogate Endpoint (SUR): Blood pressure
Study 33027046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33027046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32810358 — Surrogate Endpoint (SUR): Blood pressure
Study 32810358 — Surrogate Endpoint (SUR): Serum creatinine
Study 36646986 — Surrogate Endpoint (SUR): Probing pocket depth
Study 35587322 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35587322 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33847313 — Predictive Biomarker (PRD): ACLY mRNA
Genes: ACLY
Study 33847313 — Predictive Biomarker (PRD): SLC27A2 mRNA
Genes: SLC27A2; ACSVL1; FACVL1; FATP2; VLACS
Study 33847313 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 33847313 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35263436 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33795116 — Surrogate Endpoint (SUR): Blood pressure
Study 36414368 — Surrogate Endpoint (SUR): Blood pressure
Study 35577477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32333538 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 32333538 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 32333538 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 32333538 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 33844155 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 34994269 — Surrogate Endpoint (SUR): Blood pressure
Study 34088582 — Surrogate Endpoint (SUR): Serum creatinine
Study 34088582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34088582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35265233 — Surrogate Endpoint (SUR): Bone mineral density
Study 32123315 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study 32511226 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34509996 — Surrogate Endpoint (SUR): Serum creatinine
Study 34140041 — Pharmacodynamic Biomarker (PDY): Resting EEG oscillations
Study 37773124 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 33566122 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 33566122 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 34533783 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34390601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35910068 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35910068 — Surrogate Endpoint (SUR): Blood pressure
Study 32986904 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 32497906 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 33909150 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 36107563 — Surrogate Endpoint (SUR): Serum creatinine
Study 33341444 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 36109825 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36109825 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33261611 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 32819999 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 32536056 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 32536056 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 33932360 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 36227682 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 33185582 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 33185582 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35583869 — Surrogate Endpoint (SUR): Blood pressure
Study 33714824 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 33714824 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32189338 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 33450188 — Predictive Biomarker (PRD): KLRG1 mRNA
Genes: KLRG1; CLEC15A; MAFA; MAFAL
Study 33450188 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 33269837 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 33269837 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 33667309 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 35118644 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 35589771 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 36066991 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 32311780 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 32311780 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35903379 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32534376 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 32534376 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 34978169 — Surrogate Endpoint (SUR): Sperm parameters
Study 35112890 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33351532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32089078 — Surrogate Endpoint (SUR): Blood pressure
Study 33287836 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 33287836 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 33287836 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 33287836 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 33287836 — Safety Biomarker (SAF): Reactive oxygen species
Study 33287836 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 33075788 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 32618829 — Predictive Biomarker (PRD): OLR1 mRNA
Genes: OLR1; CLEC8A; LOX1
Study 32618829 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34259302 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 33483990 — Surrogate Endpoint (SUR): Blood pressure
Study 32589129 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 34972618 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 32938746 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32938746 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 36043784 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 32768283 — Surrogate Endpoint (SUR): Blood pressure
Study 34352501 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 34248041 — Surrogate Endpoint (SUR): Serum creatinine
Study 32493715 — Predictive Biomarker (PRD): AMY1A mRNA
Genes: AMY1A; AMY1
Study 33619569 — Surrogate Endpoint (SUR): Blood pressure
Study 33212159 — Predictive Biomarker (PRD): SLC12A2 mRNA
Genes: SLC12A2; NKCC1
Study 32575945 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32575945 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 33536096 — Surrogate Endpoint (SUR): Blood pressure
Study 32069218 — Predictive Biomarker (PRD): HSD11B1 mRNA
Genes: HSD11B1; HSD11; HSD11L; SDR26C1
Study 34763338 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 34763338 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 34763338 — Surrogate Endpoint (SUR): Serum sodium
Study 35876837 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 34288404 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 34288404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34928990 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 34928990 — Surrogate Endpoint (SUR): Serum creatinine
Study 32365359 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32039737 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 34721414 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 34721414 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34721414 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 32194094 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34743663 — Predictive Biomarker (PRD): MARCKS mRNA
Genes: MARCKS; MACS; PRKCSL
Study 32315958 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 32315958 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 32315958 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study 32315958 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): miR-146a-5p
Genes: MIR146A
Study 32315958 — Safety Biomarker (SAF): miR-9
Study 32315958 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 36181316 — Monitoring Biomarker (MOI): HBV DNA
Study 33202447 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32366224 — Surrogate Endpoint (SUR): Blood pressure
Study 33461937 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 36253987 — Surrogate Endpoint (SUR): Blood pressure
Study 32795875 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32795875 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35756497 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35869311 — Surrogate Endpoint (SUR): Blood pressure
Study 35869311 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35869311 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32781869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32591370 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 32591370 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32914554 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 33448466 — Predictive Biomarker (PRD): ANK1 mRNA
Genes: ANK1; ANK
Study 35177515 — Surrogate Endpoint (SUR): Blood pressure
Study 33751849 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32527353 — Monitoring Biomarker (MOI): Procalcitonin
Study 32527353 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32527353 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32527353 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34223734 — Predictive Biomarker (PRD): TRPV6 mRNA
Genes: TRPV6; ECAC2
Study 32664066 — Surrogate Endpoint (SUR): Blood pressure
Study 32664066 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34049809 — Safety Biomarker (SAF): Hyaluronic acid
Study 32286882 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36246130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33629536 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 32343882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32343882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33691699 — Surrogate Endpoint (SUR): Blood pressure
Study 36163721 — Predictive Biomarker (PRD): HCST mRNA
Genes: HCST; DAP10; KAP10; PIK3AP; UNQ587/PRO1157
Study 34273987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34273987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33004234 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 36349299 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32316014 — Surrogate Endpoint (SUR): Blood pressure
Study 33730349 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 33730349 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 34602396 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34958402 — Surrogate Endpoint (SUR): Bone mineral density
Study 33904585 — Safety Biomarker (SAF): Hyaluronic acid
Study 33783237 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34088270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34699549 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 34839672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35316819 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 34610257 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 32297946 — Surrogate Endpoint (SUR): Blood pressure
Study 33779376 — Surrogate Endpoint (SUR): Blood pressure
Study 34915104 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 34325499 — Predictive Biomarker (PRD): CLNK mRNA
Genes: CLNK; MIST