TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35014128 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 32682347 — Predictive Biomarker (PRD): PER3 mRNA
Genes: PER3; GIG13
Study 33593828 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 33593828 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 35864343 — Surrogate Endpoint (SUR): Bone mineral density
Study 32677855 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 32677855 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 37676213 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32548854 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 33657757 — Surrogate Endpoint (SUR): Bone mineral density
Study 32946574 — Predictive Biomarker (PRD): TACR3 mRNA
Genes: TACR3; NK3R; TAC3R
Study 33393484 — Predictive Biomarker (PRD): NANOS1 mRNA
Genes: NANOS1; NOS1
Study 33393484 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 33074729 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 32444190 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32444190 — Surrogate Endpoint (SUR): Blood pressure
Study 33004472 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35143872 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 35143872 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 32719097 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 35941676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32087425 — Surrogate Endpoint (SUR): Blood pressure
Study 32653912 — Surrogate Endpoint (SUR): Blood pressure
Study 35137532 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33963372 — Surrogate Endpoint (SUR): Blood pressure
Study 32444343 — Surrogate Endpoint (SUR): Blood pressure
Study 35212802 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 36259143 — Surrogate Endpoint (SUR): Blood pressure
Study 33750646 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 33846037 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 34183458 — Surrogate Endpoint (SUR): Blood pressure
Study 34183458 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32692247 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35990583 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35990583 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 35990583 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35990583 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34983471 — Safety Biomarker (SAF): Hyaluronic acid
Study 34480134 — Surrogate Endpoint (SUR): Blood pressure
Study 33316455 — Surrogate Endpoint (SUR): Blood pressure
Study 36480147 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 36480147 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 32571870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34508154 — Surrogate Endpoint (SUR): Blood pressure
Study 35658959 — Surrogate Endpoint (SUR): Blood pressure
Study 32245307 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32245307 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 33048789 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33048789 — Surrogate Endpoint (SUR): Blood pressure
Study 35947039 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 35947039 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35947039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34114250 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 32195928 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 35867804 — Surrogate Endpoint (SUR): Blood pressure
Study 35484991 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 35985506 — Surrogate Endpoint (SUR): Serum testosterone
Study 34251939 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 34251939 — Predictive Biomarker (PRD): SRY mRNA
Genes: SRY; TDF
Study 34251939 — Safety Biomarker (SAF): Reactive oxygen species
Study 32895571 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 35576873 — Surrogate Endpoint (SUR): Blood pressure
Study 32376505 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35486948 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 36617611 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 34506827 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 36109354 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 34795121 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 35499834 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 32771313 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 32612066 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32612066 — Surrogate Endpoint (SUR): Blood pressure
Study 35301859 — Surrogate Endpoint (SUR): Blood pressure
Study 32475446 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32519507 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32519507 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35142082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33017510 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 33022293 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32252820 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34031337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34031337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34031337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34978021 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 32917418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32579152 — Predictive Biomarker (PRD): CRCP mRNA
Genes: CRCP
Study 32634485 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 32634485 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study 35109905 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 35109905 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 33766818 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 35973803 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 36163838 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 36163838 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 36163838 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 36163838 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 36163838 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 36163838 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 36163838 — Pharmacodynamic Biomarker (PDY): 2-hydroxyglutarate
Study 33289297 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33289297 — Surrogate Endpoint (SUR): Blood pressure
Study 34915982 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35609139 — Predictive Biomarker (PRD): LYVE1 mRNA
Genes: LYVE1; CRSBP1; HAR; XLKD1; UNQ230/PRO263
Study 34262557 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 37344086 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 33879453 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 33712356 — Surrogate Endpoint (SUR): Blood pressure
Study 35610013 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35005585 — Surrogate Endpoint (SUR): Bone mineral density
Study 33451738 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 33682060 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 33682060 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 33479386 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study 35113046 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34462887 — Safety Biomarker (SAF): Hyaluronic acid
Study 34684481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32212801 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 33410912 — Surrogate Endpoint (SUR): Serum uric acid
Study 33595776 — Predictive Biomarker (PRD): ACSM3 mRNA
Genes: ACSM3; SAH
Study 36163929 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 33604379 — Surrogate Endpoint (SUR): Serum creatinine
Study 34039560 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34032505 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32830553 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 35098970 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 35793982 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 35793982 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32651132 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 35295073 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35411074 — Predictive Biomarker (PRD): TRIM32 mRNA
Genes: TRIM32; HT2A
Study 32524424 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 33720272 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 36363460 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32250057 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 33638612 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 32235773 — Surrogate Endpoint (SUR): Blood pressure
Study 32235773 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33984356 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35060389 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32018252 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 34112656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32925765 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33225995 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32557731 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 32883322 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34667294 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 34667294 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 34052211 — Surrogate Endpoint (SUR): Blood pressure
Study 33135737 — Predictive Biomarker (PRD): LEAP2 mRNA
Genes: LEAP2
Study 35134170 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 35134170 — Surrogate Endpoint (SUR): Blood pressure
Study 34321316 — Predictive Biomarker (PRD): FFAR1 mRNA
Genes: FFAR1; GPR40
Study 35857127 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33568088 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32559272 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 34602349 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 34602349 — Surrogate Endpoint (SUR): Pathological complete response
Study 32723264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32773013 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34096894 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 35963369 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 35920250 — Surrogate Endpoint (SUR): Serum potassium
Study 35859928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35859928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34313232 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32444035 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32444035 — Surrogate Endpoint (SUR): Blood pressure
Study 34516655 — Predictive Biomarker (PRD): HSPA2 mRNA
Genes: HSPA2
Study 34516655 — Surrogate Endpoint (SUR): Sperm parameters
Study 35656824 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 35656824 — Surrogate Endpoint (SUR): Blood pressure
Study 33484896 — Surrogate Endpoint (SUR): Blood pressure
Study 35241434 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35988194 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35988194 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 35988194 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 32918135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 33252489 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 616277788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33526728 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34814819 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34474433 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34474433 — Predictive Biomarker (PRD): RAB11FIP1 mRNA
Genes: RAB11FIP1; RCP
Study 32967775 — Surrogate Endpoint (SUR): Bone mineral density
Study 32219386 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32219386 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33465658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33465658 — Surrogate Endpoint (SUR): Blood pressure
Study 33465658 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33465658 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35688618 — Surrogate Endpoint (SUR): Blood pressure
Study 35988343 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 33590947 — Surrogate Endpoint (SUR): Blood pressure
Study 34890069 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35876047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 32403934 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 32403934 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32403934 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32554646 — Surrogate Endpoint (SUR): Blood pressure
Study 36357960 — Surrogate Endpoint (SUR): Bone mineral density
Study 36130275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36130275 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 32915800 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 33854404 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 33854404 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 33854404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32480364 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 34120912 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 33272980 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 33272980 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 35467561 — Surrogate Endpoint (SUR): Blood pressure
Study 34431828 — Surrogate Endpoint (SUR): Bone mineral density
Study 34960037 — Surrogate Endpoint (SUR): Blood pressure
Study 34960037 — Surrogate Endpoint (SUR): Serum creatinine
Study 34453873 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 34453873 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34405232 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36495185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36495185 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33259482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 33285652 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 35332291 — Predictive Biomarker (PRD): ETV5 mRNA
Genes: ETV5; ERM
Study 35332291 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 34323164 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32827162 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33598693 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 35385061 — Predictive Biomarker (PRD): DOCK3 mRNA
Genes: DOCK3; KIAA0299; MOCA
Study 33085170 — Safety Biomarker (SAF): Hyaluronic acid
Study 33081788 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33896590 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33896590 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 36178169 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 34183565 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 34183565 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 34183565 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 35567872 — Surrogate Endpoint (SUR): Blood pressure
Study 34110902 — Safety Biomarker (SAF): Reactive oxygen species
Study 34187938 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 34340708 — Predictive Biomarker (PRD): HIPK2 mRNA
Genes: HIPK2
Study 34340708 — Predictive Biomarker (PRD): PPP1CC mRNA
Genes: PPP1CC
Study 34765938 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36075590 — Predictive Biomarker (PRD): DLL4 mRNA
Genes: DLL4; UNQ1895/PRO4341
Study 36075590 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 36135347 — Surrogate Endpoint (SUR): Blood pressure
Study 35842871 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 36107485 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 35639038 — Surrogate Endpoint (SUR): Blood pressure
Study 32077525 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34368894 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 34368894 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 34368894 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 34368894 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34368894 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 32605893 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34562081 — Surrogate Endpoint (SUR): Blood pressure
Study 34774089 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32228673 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 32471729 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 32700098 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 34462286 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34285006 — Surrogate Endpoint (SUR): Blood pressure
Study 32278278 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 36017028 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 36017028 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32768592 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 35499569 — Predictive Biomarker (PRD): TNFRSF18 mRNA
Genes: TNFRSF18; AITR; GITR; UNQ319/PRO364
Study 33553097 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 33156550 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 35226949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34960007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34960007 — Surrogate Endpoint (SUR): Serum triglycerides
Study 32736776 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32736776 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 32966830 — Surrogate Endpoint (SUR): Pathological complete response
Study 33711671 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 616497225 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 616497225 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34783447 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 34783447 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 33795720 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34028298 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125