TrialPanorama/TrialPanorama-database huggingface dataset:
Study 34758069 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 36056388 — Surrogate Endpoint (SUR): Blood pressure
Study 35385090 — Predictive Biomarker (PRD): EPRS1 mRNA
Genes: EPRS1; EPRS; GLNS; PARS; QARS; QPRS; PIG32
Study 33975736 — Surrogate Endpoint (SUR): Serum uric acid
Study 35236752 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 35312632 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 36463165 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 36125053 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32522363 — Predictive Biomarker (PRD): NPR2 mRNA
Genes: NPR2; ANPRB
Study 32522363 — Predictive Biomarker (PRD): NPR1 mRNA
Genes: NPR1; ANPRA
Study 35169169 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 35848060 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 34248926 — Predictive Biomarker (PRD): CREBBP mRNA
Genes: CREBBP; CBP
Study 34248926 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 34248926 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 34248926 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 34248926 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32475445 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32077891 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32077891 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 32199184 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 35857131 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 35822542 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 35822542 — Monitoring Biomarker (MOI): miR-24-3p
Study 35822542 — Predictive Biomarker (PRD): miR-145
Genes: MIR145
Study 35822542 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 35822542 — Predictive Biomarker (PRD): miR-21-5p
Genes: MIR21
Study 35822542 — Predictive Biomarker (PRD): miR-372-3p
Genes: MIR372
Study 32363765 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32363765 — Safety Biomarker (SAF): Interleukin 1
Study 36207993 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32723675 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33357965 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 33357965 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 32500753 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 33333328 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 33808079 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 32576828 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33715937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33715937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36223321 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32890808 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32890808 — Surrogate Endpoint (SUR): Blood pressure
Study 33951328 — Surrogate Endpoint (SUR): Bone mineral density
Study 32146471 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 34621271 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 33788482 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32492148 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 32961293 — Predictive Biomarker (PRD): LYZ mRNA
Genes: LYZ; LZM
Study 32961293 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32145678 — Predictive Biomarker (PRD): GMCL2 mRNA
Genes: GMCL2; GCL; GMCL1L; GMCL1P1
Study 33518311 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 35850588 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34936992 — Surrogate Endpoint (SUR): Bone mineral density
Study 35566250 — Safety Biomarker (SAF): Reactive oxygen species
Study 33901276 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 32427280 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 35422134 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33348678 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 33348678 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33348678 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 33348678 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33348678 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35326326 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 33669905 — Surrogate Endpoint (SUR): Blood pressure
Study 36501148 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36501148 — Surrogate Endpoint (SUR): Blood pressure
Study 36342251 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 35583992 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35583992 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 34750670 — Surrogate Endpoint (SUR): Blood pressure
Study 32701242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32701242 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32701242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34689382 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34689382 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 34689382 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 35841050 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35841050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35841050 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34548307 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32760749 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 32760749 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 33085516 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study 33085516 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 33085516 — Predictive Biomarker (PRD): ACAT2 mRNA
Genes: ACAT2; ACTL
Study 33085516 — Predictive Biomarker (PRD): ACLY mRNA
Genes: ACLY
Study 33085516 — Predictive Biomarker (PRD): ABCG5 mRNA
Genes: ABCG5
Study 33085516 — Predictive Biomarker (PRD): ABCG8 mRNA
Genes: ABCG8
Study 36177347 — Monitoring Biomarker (MOI): HBV DNA
Study 36177347 — Surrogate Endpoint (SUR): Bone mineral density
Study 33603000 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 32182380 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 36114824 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36114824 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 36114824 — Safety Biomarker (SAF): BDNF
Study 34343033 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 34343033 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 32600363 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 32600363 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 33103950 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 33103950 — Predictive Biomarker (PRD): PEBP1 mRNA
Genes: PEBP1; PBP; PEBP
Study 34496899 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 34496899 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 37823711 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study 33589575 — Predictive Biomarker (PRD): RNASE2 mRNA
Genes: RNASE2; EDN; RNS2
Study 33589575 — Predictive Biomarker (PRD): METTL1 mRNA
Genes: METTL1; C12orf1
Study 33589575 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 33589575 — Predictive Biomarker (PRD): YBX2 mRNA
Genes: YBX2; CSDA3; MSY2
Study 35072431 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36117971 — Surrogate Endpoint (SUR): Blood pressure
Study 34146026 — Predictive Biomarker (PRD): ASPH mRNA
Genes: ASPH; BAH
Study 32278858 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 36477809 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 36250147 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 33655352 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 34383532 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33932411 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 33159796 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36014954 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 35545781 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 35545781 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 33677520 — Surrogate Endpoint (SUR): Blood pressure
Study 34924332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34924332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34924332 — Safety Biomarker (SAF): Interleukin 1
Study 34924332 — Safety Biomarker (SAF): IL-6 and IL-10
Study 33522698 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 33525934 — Safety Biomarker (SAF): Cytochrome c
Study 33340514 — Surrogate Endpoint (SUR): Blood pressure
Study 33186351 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33948768 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 34373987 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32875989 — Surrogate Endpoint (SUR): Blood pressure
Study 32761176 — Predictive Biomarker (PRD): TMPRSS13 mRNA
Genes: TMPRSS13; MSP; TMPRSS11
Study 36299880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36299880 — Surrogate Endpoint (SUR): Bone mineral density
Study 616625220 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 33694358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33694358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33694358 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 33694358 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 33694358 — Surrogate Endpoint (SUR): Blood pressure
Study 33451978 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34850657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32044905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32044905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32044905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32766852 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 32766852 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33908815 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32815648 — Surrogate Endpoint (SUR): Blood pressure
Study 33367925 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 33367925 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 33367925 — Predictive Biomarker (PRD): CDCA3 mRNA
Genes: CDCA3; C8; GRCC8; TOME1
Study 32485734 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32485734 — Surrogate Endpoint (SUR): Blood pressure
Study 35586668 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 35586668 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35586668 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33606920 — Surrogate Endpoint (SUR): Serum creatinine
Study 32617646 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 35715930 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 35715930 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 34408396 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33002440 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 35550374 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 35729430 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 34477291 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 32894190 — Monitoring Biomarker (MOI): Apolipoprotein A-IV
Genes: APOA4
Study 33395687 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 34081897 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 36331152 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 36331152 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32232885 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 35815057 — Surrogate Endpoint (SUR): Blood pressure
Study 35815057 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34154603 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 34154603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34154603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34154603 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 36204783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32883286 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34984794 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 34984794 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32397609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36427543 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 36427543 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 33657998 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 34511168 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34511168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34511168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34511168 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 34511168 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 34511168 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study 32067367 — Surrogate Endpoint (SUR): Bone mineral density
Study 34010531 — Surrogate Endpoint (SUR): Blood pressure
Study 35017008 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 33727261 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33435881 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32414956 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 32506827 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 33666378 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 37399894 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 34425851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34425851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 616877161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36227893 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 36227893 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 36227893 — Predictive Biomarker (PRD): C4BPA mRNA
Genes: C4BPA; C4BP
Study 32885440 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 32885440 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32885440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36334119 — Surrogate Endpoint (SUR): Bone mineral density
Study 35758855 — Surrogate Endpoint (SUR): Blood pressure
Study 35758855 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35758855 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 34121642 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 34121642 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 34121642 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 34378852 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 36288831 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 33561153 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33561153 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36113394 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 36113394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36113394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35016413 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 33964979 — Predictive Biomarker (PRD): RIT1 mRNA
Genes: RIT1; RIBB; RIT; ROC1
Study 33664086 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33187978 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 33187978 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 35350988 — Surrogate Endpoint (SUR): Blood pressure
Study 32347365 — Predictive Biomarker (PRD): PIANP mRNA
Genes: PIANP; C12orf53; PANP; UNQ828/PRO1755
Study 33787151 — Surrogate Endpoint (SUR): Blood pressure
Study 36388664 — Safety Biomarker (SAF): IL-6 and IL-10
Study 32414888 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 32198939 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 35869266 — Predictive Biomarker (PRD): ACVR1 mRNA
Genes: ACVR1; ACVRLK2
Study 35869266 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 35869266 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 33247012 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 33247012 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 32645251 — Predictive Biomarker (PRD): OR2AT4 mRNA
Genes: OR2AT4
Study 35401778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32649736 — Monitoring Biomarker (MOI): HBV DNA
Study 34429340 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 34429340 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 34429340 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 34321304 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 35049677 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 36126454 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34221251 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32941476 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32941476 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 32941476 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 36032232 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 36032232 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35123457 — Surrogate Endpoint (SUR): Blood pressure
Study 35332685 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 36273151 — Predictive Biomarker (PRD): PDP1 mRNA
Genes: PDP1; PDP; PPM2C
Study 32503806 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 616681315 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 32105310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33046533 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 32565333 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 32565333 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35586674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2