TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33811747 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36314990 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 36314990 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 33782552 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study 32807241 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32807241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32131611 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 35807781 — Surrogate Endpoint (SUR): Blood pressure
Study 35791089 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32372486 — Surrogate Endpoint (SUR): Bone mineral density
Study 35860190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35860190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35860190 — Monitoring Biomarker (MOI): Procalcitonin
Study 35860190 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32053417 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32053417 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32053417 — Surrogate Endpoint (SUR): Blood pressure
Study 33207094 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 33910879 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32682696 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 32682696 — Surrogate Endpoint (SUR): Blood pressure
Study 32682696 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 36060926 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 36060926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36060926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36060926 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 35293006 — Surrogate Endpoint (SUR): Hematologic response
Study 35713517 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35713517 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 35713517 — Predictive Biomarker (PRD): Hormone receptor
Study 32613525 — Predictive Biomarker (PRD): MARCKS mRNA
Genes: MARCKS; MACS; PRKCSL
Study 32825556 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32825556 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34727317 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 35331859 — Safety Biomarker (SAF): Hyaluronic acid
Study 33038521 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 34467386 — Surrogate Endpoint (SUR): Blood pressure
Study 34837890 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 34473194 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 33516273 — Predictive Biomarker (PRD): BIN1 mRNA
Genes: BIN1; AMPHL
Study 36017745 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 36916653 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 32861273 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 32861273 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 32861273 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34212195 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 34105575 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34105575 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 32114796 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33560531 — Surrogate Endpoint (SUR): Bacterial count
Study 35143747 — Predictive Biomarker (PRD): SGCA mRNA
Genes: SGCA; ADL; DAG2
Study 33491087 — Surrogate Endpoint (SUR): Blood pressure
Study 34032727 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 34816762 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 32303437 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 32303437 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32303437 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32278735 — Surrogate Endpoint (SUR): Serum creatinine
Study 35916347 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35562205 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 35168036 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33097977 — Safety Biomarker (SAF): Interleukin 1
Study 33449097 — Surrogate Endpoint (SUR): Blood pressure
Study 32885583 — Surrogate Endpoint (SUR): Serum creatinine
Study 35381530 — Predictive Biomarker (PRD): LEF1 mRNA
Genes: LEF1
Study 35381530 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CTNNB1 mRNA
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study 34274555 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 34274555 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 35596008 — Surrogate Endpoint (SUR): Blood pressure
Study 33877440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 35921023 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34713825 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34713825 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32789505 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32156534 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 32156534 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 35787135 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 35846327 — Surrogate Endpoint (SUR): Pathological complete response
Study 36130755 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 36114137 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33610902 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33246021 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 33246021 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 33246021 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33246021 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33246021 — Predictive Biomarker (PRD): Hormone receptor
Study 34174474 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 36250662 — Safety Biomarker (SAF): Interleukin 1
Study 33002553 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 36309760 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 34328151 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34718239 — Predictive Biomarker (PRD): PIM2 mRNA
Genes: PIM2
Study 34718239 — Predictive Biomarker (PRD): SPI1 mRNA
Genes: SPI1
Study 34718239 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 34718239 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 616791867 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 616791867 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36030401 — Surrogate Endpoint (SUR): Blood pressure
Study 33788461 — Surrogate Endpoint (SUR): Bone mineral density
Study 33863751 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 32510250 — Surrogate Endpoint (SUR): Blood pressure
Study 33587132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33587132 — Surrogate Endpoint (SUR): Blood pressure
Study 33587132 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32240122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36026684 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 35253570 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 33872709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35610014 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33482853 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33482853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33482853 — Surrogate Endpoint (SUR): Blood pressure
Study 33300853 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33050401 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 33539955 — Surrogate Endpoint (SUR): Blood pressure
Study 34102144 — Predictive Biomarker (PRD): TPSG1 mRNA
Genes: TPSG1; PRSS31; TMT
Study 34275209 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 32275359 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34154510 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 36334720 — Surrogate Endpoint (SUR): Blood pressure
Study 32616246 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32030508 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 32030508 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32678452 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 34473026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35678800 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 34259398 — Monitoring Biomarker (MOI): Procalcitonin
Study 34259398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34259398 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32111313 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 33340376 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 35301810 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 32333707 — Surrogate Endpoint (SUR): Blood pressure
Study 33303928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33303928 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33303928 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study 36164138 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 33739218 — Safety Biomarker (SAF): XRCC1
Genes: RCC
Study 35668633 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33636416 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 36198461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36198461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36198461 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 35217515 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 35217515 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35217515 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32080074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33653745 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32034403 — Predictive Biomarker (PRD): AMY1A mRNA
Genes: AMY1A; AMY1
Study 33199226 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33199226 — Safety Biomarker (SAF): Reactive oxygen species
Study 35246099 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 35246099 — Surrogate Endpoint (SUR): Blood pressure
Study 33327282 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35412099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32757302 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 35182925 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 34078367 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 34078367 — Surrogate Endpoint (SUR): Sperm parameters
Study 33909330 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 33909330 — Surrogate Endpoint (SUR): Serum potassium
Study 34257675 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34257675 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 35193041 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 33824980 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 35762095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35762095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32928024 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 33372320 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 34593990 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33581737 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 33581737 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 33581737 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 33581737 — Predictive Biomarker (PRD): PECAM1 mRNA
Genes: PECAM1
Study 33581737 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33581737 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 36214938 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 34100769 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33983794 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33983794 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 35534640 — Surrogate Endpoint (SUR): Blood pressure
Study 34261541 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34054053 — Surrogate Endpoint (SUR): Blood pressure
Study 32881071 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 32615488 — Surrogate Endpoint (SUR): Blood pressure
Study 32615488 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32615994 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34802039 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 34802039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33951374 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33951374 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33305526 — Surrogate Endpoint (SUR): Blood pressure
Study 33328728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33076878 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 33076878 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33009239 — Surrogate Endpoint (SUR): Bone mineral density
Study 32843171 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 35219331 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 35219331 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34043794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34043794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34043794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33091856 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33091856 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 34144104 — Surrogate Endpoint (SUR): Blood pressure
Study 36192552 — Predictive Biomarker (PRD): GCGR mRNA
Genes: GCGR
Study 36192552 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36192552 — Surrogate Endpoint (SUR): Blood pressure
Study 32568134 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 33079022 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34569641 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 32778721 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32778721 — Safety Biomarker (SAF): BDNF
Study 33893329 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study 32839029 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34351377 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 36111475 — Surrogate Endpoint (SUR): Bone mineral density
Study 33415860 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35169165 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 33636278 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 35995816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32386891 — Surrogate Endpoint (SUR): Blood pressure
Study 35849445 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33091706 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 33091706 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34229729 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34229729 — Surrogate Endpoint (SUR): Blood pressure
Study 33421558 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32313032 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36040464 — Surrogate Endpoint (SUR): Serum sodium
Study 33221116 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 34038410 — Surrogate Endpoint (SUR): Blood pressure
Study 616811449 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 616811449 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 34677647 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 32546217 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32669656 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 32669656 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 36135387 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 32822656 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 33032485 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 32573910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32573910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32573910 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 32573910 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32573910 — Surrogate Endpoint (SUR): Bone mineral density
Study 32573910 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32340524 — Surrogate Endpoint (SUR): Blood pressure
Study 616186217 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 616186217 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study 616186217 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 616186217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33888136 — Predictive Biomarker (PRD): PSMB7 mRNA
Genes: PSMB7; Z
Study 36190391 — Surrogate Endpoint (SUR): Bone mineral density
Study 34607144 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34239883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34467453 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 33269889 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33512013 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36472034 — Predictive Biomarker (PRD): MAP3K5 mRNA
Genes: MAP3K5; ASK1; MAPKKK5; MEKK5
Study 36472034 — Predictive Biomarker (PRD): MAP2K4 mRNA
Genes: MAP2K4; JNKK1; MEK4; MKK4; PRKMK4; SEK1; SERK1; SKK1
Study 34406619 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 35689272 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 35129994 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 36344308 — Surrogate Endpoint (SUR): Blood pressure
Study 36344308 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34137526 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 34137526 — Surrogate Endpoint (SUR): Blood pressure
Study 34767495 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34549258 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 34549258 — Surrogate Endpoint (SUR): Blood pressure