TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35648242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34077644 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 32000559 — Predictive Biomarker (PRD): Hormone receptor
Study 33232739 — Surrogate Endpoint (SUR): Blood pressure
Study 32755254 — Surrogate Endpoint (SUR): Blood pressure
Study 33740276 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 34887572 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33663581 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 33663581 — Surrogate Endpoint (SUR): Blood pressure
Study 33663581 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32152335 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 32492302 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35973626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32666238 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 35467140 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 32324197 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34267006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34980810 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 34980810 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study 33372280 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 32019575 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 34274848 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34274848 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 35700741 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 32034070 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 37027131 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 37027131 — Surrogate Endpoint (SUR): Blood pressure
Study 33522249 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33522249 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33522249 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34821943 — Surrogate Endpoint (SUR): Bone mineral density
Study 35186297 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 34152804 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 34152804 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 34019661 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 34920097 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 36972981 — Surrogate Endpoint (SUR): Blood pressure
Study 34620312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35998839 — Predictive Biomarker (PRD): MAP3K15 mRNA
Genes: MAP3K15; ASK3
Study 35998839 — Predictive Biomarker (PRD): MAPK10 mRNA
Genes: MAPK10; JNK3; JNK3A; PRKM10; SAPK1B
Study 35998839 — Predictive Biomarker (PRD): ADAMTS1 mRNA
Genes: ADAMTS1; KIAA1346; METH1
Study 34224503 — Predictive Biomarker (PRD): UBB mRNA
Genes: UBB
Study 36153281 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36153281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36098670 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 33666540 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 35881420 — Surrogate Endpoint (SUR): Blood pressure
Study 32119192 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33342316 — Surrogate Endpoint (SUR): Blood pressure
Study 33059620 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 34087678 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33357480 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 32699180 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 32623925 — Surrogate Endpoint (SUR): Blood pressure
Study 35915733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32638504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32638504 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 33298617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32527283 — Surrogate Endpoint (SUR): Blood pressure
Study 32306007 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36434692 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 34738551 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 34738551 — Surrogate Endpoint (SUR): Serum creatinine
Study 34738551 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 34738551 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 32543706 — Predictive Biomarker (PRD): BMP6 mRNA
Genes: BMP6; VGR
Study 32543706 — Surrogate Endpoint (SUR): Bone mineral density
Study 35006243 — Surrogate Endpoint (SUR): Blood pressure
Study 32125188 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 32125188 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35074904 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33271891 — Surrogate Endpoint (SUR): Blood pressure
Study 34881930 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34819115 — Surrogate Endpoint (SUR): Blood pressure
Study 34611065 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34611065 — Safety Biomarker (SAF): Hyaluronic acid
Study 32319204 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 33122738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33122738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33122738 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 33122738 — Safety Biomarker (SAF): IL16
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 32794259 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 34521108 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32948200 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 33247306 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 32291620 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33034409 — Predictive Biomarker (PRD): RNPC3 mRNA
Genes: RNPC3; KIAA1839; RBM40; RNP; SNRNP65
Study 33509019 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 32597565 — Surrogate Endpoint (SUR): Blood pressure
Study 32546648 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32546648 — Predictive Biomarker (PRD): Hormone receptor
Study 32710602 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 36170550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32726200 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32176092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36468403 — Surrogate Endpoint (SUR): Blood pressure
Study 36317751 — Surrogate Endpoint (SUR): Serum uric acid
Study 33017456 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33017456 — Surrogate Endpoint (SUR): Serum creatinine
Study 33017456 — Surrogate Endpoint (SUR): Blood pressure
Study 32195538 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32195538 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 32195538 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 32195538 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 32195538 — Predictive Biomarker (PRD): GCKR mRNA
Genes: GCKR
Study 32195538 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 35287025 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32865108 — Surrogate Endpoint (SUR): Blood pressure
Study 35608639 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 35608639 — Surrogate Endpoint (SUR): Bone mineral density
Study 34648847 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 32996010 — Surrogate Endpoint (SUR): Blood pressure
Study 33351781 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study 33351781 — Predictive Biomarker (PRD): KLRG1 mRNA
Genes: KLRG1; CLEC15A; MAFA; MAFAL
Study 33351781 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): GZMB mRNA
Genes: GZMB; CGL1; CSPB; CTLA1; GRB
Study 33351781 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 34506606 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32791692 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 33938492 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 34544820 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 35083878 — Surrogate Endpoint (SUR): Blood pressure
Study 33121452 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 33744088 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36219809 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32473563 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32473563 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study 32473563 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 32473563 — Safety Biomarker (SAF): BDNF
Study 34935407 — Surrogate Endpoint (SUR): Blood pressure
Study 33315342 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 33652129 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 32132590 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 33301990 — Surrogate Endpoint (SUR): Blood pressure
Study 32147440 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 36090495 — Surrogate Endpoint (SUR): Blood pressure
Study 33343579 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 33343579 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 33343579 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study 33343579 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 35397367 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35397367 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33113535 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 32067218 — Predictive Biomarker (PRD): MANF mRNA
Genes: MANF; ARMET; ARP
Study 35608580 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35608580 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35608580 — Predictive Biomarker (PRD): Hormone receptor
Study 35608580 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32409838 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34341520 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 34341520 — Surrogate Endpoint (SUR): Annualized growth velocity
Study 33923532 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 35242209 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 35242209 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 32491923 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 35120199 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33059911 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 32681739 — Surrogate Endpoint (SUR): Hematologic response
Study 33503302 — Surrogate Endpoint (SUR): Blood pressure
Study 34962559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34811502 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 34880957 — Predictive Biomarker (PRD): TSN mRNA
Genes: TSN
Study 34880957 — Safety Biomarker (SAF): miR-205
Genes: MIR205
Study 35986934 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 35484744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35484744 — Predictive Biomarker (PRD): miR-106a
Genes: MIR106A
Study 35484744 — Safety Biomarker (SAF): Reactive oxygen species
Study 32295092 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 33574076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 616063739 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35897022 — Surrogate Endpoint (SUR): Blood pressure
Study 33977310 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 35873227 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 32861275 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 32861275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32861275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35561315 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33295397 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32740409 — Surrogate Endpoint (SUR): Blood pressure
Study 34344427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34344427 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34246303 — Predictive Biomarker (PRD): PAX7 mRNA
Genes: PAX7; HUP1
Study 34246303 — Predictive Biomarker (PRD): MYOD1 mRNA
Genes: MYOD1; BHLHC1; MYF3; MYOD
Study 33256456 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 35662283 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 35662283 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33761458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33761458 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 33761458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33761458 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33761458 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36342113 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33323188 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 34445008 — Surrogate Endpoint (SUR): Bone mineral density
Study 33866774 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33548084 — Surrogate Endpoint (SUR): Blood pressure
Study 35969408 — Surrogate Endpoint (SUR): Blood pressure
Study 33186774 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33186774 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 36727153 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 36350593 — Surrogate Endpoint (SUR): Blood pressure
Study 32609331 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34620496 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 33268527 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35819787 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 33780749 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33027448 — Surrogate Endpoint (SUR): Blood pressure
Study 33027448 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33452059 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33212268 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 33212268 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32737344 — Surrogate Endpoint (SUR): Blood pressure
Study 32975556 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32789480 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 32789480 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 32789480 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34515079 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 33407848 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 35809206 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34792562 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 34792562 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 34792562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32168067 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 32212089 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32212089 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32402609 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 33060491 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33060491 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 33060491 — Surrogate Endpoint (SUR): Blood pressure
Study 35389428 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35279972 — Surrogate Endpoint (SUR): Blood pressure
Study 32060260 — Predictive Biomarker (PRD): DLEU7 mRNA
Genes: DLEU7; LEU7
Study 32060260 — Predictive Biomarker (PRD): MSRB3 mRNA
Genes: MSRB3; UNQ1965/PRO4487
Study 32063059 — Surrogate Endpoint (SUR): Blood pressure
Study 32267205 — Surrogate Endpoint (SUR): Bone mineral density
Study 32532687 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32167794 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32167794 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 33686407 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 35477876 — Surrogate Endpoint (SUR): Blood pressure
Study 36240972 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 33614699 — Monitoring Biomarker (MOI): Procalcitonin
Study 33614699 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32392715 — Surrogate Endpoint (SUR): Blood pressure
Study 33470646 — Surrogate Endpoint (SUR): Blood pressure
Study 32367437 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 32367437 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 32367437 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 35098682 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33076902 — Surrogate Endpoint (SUR): Bone mineral density
Study 35021015 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32517192 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 32517192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32517192 — Safety Biomarker (SAF): Interleukin 1
Study 33037656 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 33037656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34150674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34150674 — Safety Biomarker (SAF): IL-6 and IL-10
Study 35833298 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 34228086 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 32755065 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 32375688 — Predictive Biomarker (PRD): PTGDS mRNA
Genes: PTGDS; PDS
Study 32375688 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 32375688 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 35569564 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35569564 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 32762115 — Surrogate Endpoint (SUR): Blood pressure
Study 32762115 — Surrogate Endpoint (SUR): Serum uric acid
Study 33516644 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study 33516644 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 33516644 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36454825 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33704913 — Surrogate Endpoint (SUR): Blood pressure
Study 36169441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36169441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36169441 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35389424 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL