TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33441158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34015241 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32160058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35051263 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study 35051263 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 32207354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32207354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34126053 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32236602 — Safety Biomarker (SAF): Reactive oxygen species
Study 33634831 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 34849536 — Surrogate Endpoint (SUR): Bone mineral density
Study 32359376 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32359376 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33160266 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 35443789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34535522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34535522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35101183 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34607344 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 32771002 — Surrogate Endpoint (SUR): Blood pressure
Study 35416502 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 32959502 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32413284 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 32413284 — Predictive Biomarker (PRD): SARM1 mRNA
Genes: SARM1; KIAA0524; SAMD2; SARM
Study 32413284 — Predictive Biomarker (PRD): SNX32 mRNA
Genes: SNX32; SNX6B
Study 32413284 — Predictive Biomarker (PRD): CTSH mRNA
Genes: CTSH; CPSB
Study 32413284 — Safety Biomarker (SAF): Netrin-1
Genes: NTN1; NTN1L
Study 36261812 — Surrogate Endpoint (SUR): Blood pressure
Study 35986421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35986421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35986421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32498088 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 32279529 — Surrogate Endpoint (SUR): Blood pressure
Study 32599106 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 33953123 — Predictive Biomarker (PRD): OPRD1 mRNA
Genes: OPRD1; OPRD
Study 32233959 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 35037278 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 36306283 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 34029555 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 34309427 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 34098827 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34098827 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34098827 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 34098827 — Predictive Biomarker (PRD): Hormone receptor
Study 35254665 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 34425776 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 33310698 — Surrogate Endpoint (SUR): Blood pressure
Study 33493393 — Surrogate Endpoint (SUR): Bone mineral density
Study 33086239 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 32780946 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 35977807 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 34338136 — Safety Biomarker (SAF): miR-216b
Genes: MIR216B
Study 33378478 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 35165387 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35165387 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 35165387 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 32907904 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35631137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35631137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33739852 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 33739852 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 32921069 — Predictive Biomarker (PRD): Hormone receptor
Study 33253933 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 32602362 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 35234092 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 33399273 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 32452344 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 32452344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32299093 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 32299093 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 32299093 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 35235653 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 35235653 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35084948 — Predictive Biomarker (PRD): Hormone receptor
Study 35084948 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 34398667 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 32166899 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 32166899 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 32166899 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 32166899 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34407667 — Surrogate Endpoint (SUR): Blood pressure
Study 34351608 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34353696 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Interleukin 6 receptor alpha
Genes: IL6R
Study 34353696 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36265753 — Surrogate Endpoint (SUR): Blood pressure
Study 36265753 — Surrogate Endpoint (SUR): Serum creatinine
Study 32857933 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 32857933 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 32857933 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 36147166 — Surrogate Endpoint (SUR): Blood pressure
Study 34340595 — Surrogate Endpoint (SUR): Blood pressure
Study 36371180 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 34684393 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34684393 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34684393 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35344737 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 35344737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32696178 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32696178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32696178 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34554368 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 34380150 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34380150 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32994187 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32544011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32544011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32544011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32544011 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 33455201 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 32641320 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34921121 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 32877576 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36099876 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 36099876 — Surrogate Endpoint (SUR): Serum creatinine
Study 36331328 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 36331328 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36331328 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 36331328 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 36331328 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 36331328 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 34006921 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34006921 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 34006921 — Predictive Biomarker (PRD): CSF1 mRNA
Genes: CSF1
Study 34006921 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36206152 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 35176724 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 33150385 — Surrogate Endpoint (SUR): Bone mineral density
Study 36394384 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 34628740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34628740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34159451 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 32928387 — Safety Biomarker (SAF): Cytochrome c
Study 32001832 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32001832 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32001832 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 34673954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32382784 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 32825845 — Predictive Biomarker (PRD): TOB1 mRNA
Genes: TOB1; TOB; TROB1
Study 32825845 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 32825845 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 35281985 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 33293212 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 33293212 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 36921715 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32534120 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 34275476 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33633687 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 34747516 — Surrogate Endpoint (SUR): Bone mineral density
Study 34747516 — Surrogate Endpoint (SUR): Serum calcium
Study 35568638 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 35568638 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 35050943 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 35050943 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35038433 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32927324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32702315 — Predictive Biomarker (PRD): FAIM mRNA
Genes: FAIM; FAIM1
Study 35674042 — Surrogate Endpoint (SUR): Blood pressure
Study 33880813 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 33880813 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36396438 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33333295 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 33028390 — Surrogate Endpoint (SUR): Bone mineral density
Study 34423832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34423832 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34423832 — Safety Biomarker (SAF): BDNF
Study 34347776 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 32874098 — Surrogate Endpoint (SUR): Blood pressure
Study 35986259 — Surrogate Endpoint (SUR): Blood pressure
Study 34390762 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 35831736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35831736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35831736 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 35904770 — Surrogate Endpoint (SUR): Probing pocket depth
Study 34495376 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 34495376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36157208 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 36157208 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 36157208 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34636899 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 36173344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36173344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33174467 — Surrogate Endpoint (SUR): Blood pressure
Study 32534515 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32534515 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32534515 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36818483 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 34540188 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34540188 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33605677 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33851255 — Safety Biomarker (SAF): Hyaluronic acid
Study 34406530 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 35611683 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 36361239 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33155754 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 34680123 — Safety Biomarker (SAF): Hyaluronic acid
Study 32483134 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 32483134 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 32483134 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 32483134 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 32483134 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 33079884 — Surrogate Endpoint (SUR): Blood pressure
Study 32116251 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 33717194 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32568642 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 36357712 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34412705 — Surrogate Endpoint (SUR): Blood pressure
Study 35299288 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 35299288 — Surrogate Endpoint (SUR): Blood pressure
Study 32128865 — Surrogate Endpoint (SUR): Blood pressure
Study 35657540 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 35290169 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 32638023 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 33896333 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 34839016 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34651349 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 34651349 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32273682 — Surrogate Endpoint (SUR): Blood pressure
Study 33827848 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34816612 — Surrogate Endpoint (SUR): Blood pressure
Study 35279338 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 35279338 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 35279338 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 34872404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35905752 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34875345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36180132 — Surrogate Endpoint (SUR): Serum calcium
Study 32460584 — Surrogate Endpoint (SUR): Blood pressure
Study 33046214 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 33046214 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 33046214 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 33046214 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study 33046214 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study 33046214 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 33046214 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 616869714 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 33792646 — Predictive Biomarker (PRD): Microsatellite instability
Study 32147197 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32147197 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 36319059 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 36495036 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 32955177 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34937036 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33531075 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35388321 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 32798689 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 37937943 — Surrogate Endpoint (SUR): Blood pressure
Study 32453913 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 36397217 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36397217 — Safety Biomarker (SAF): BDNF
Study 32674235 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34890212 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 34890212 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32525743 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 32525743 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 32525743 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35597443 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 35916348 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35916348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32366927 — Surrogate Endpoint (SUR): Blood pressure
Study 34391418 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 35144636 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 34537830 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 34824052 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 33813328 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1