TrialPanorama/TrialPanorama-database huggingface dataset:
Study 34032151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34032151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35737911 — Predictive Biomarker (PRD): CLEC4D mRNA
Genes: CLEC4D; CLECSF8; MCL
Study 35737911 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 35737911 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32503727 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 35800224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35800224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35800224 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 35800224 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32640554 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35454330 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35454330 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34465469 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 32384397 — Safety Biomarker (SAF): IL-6 and IL-10
Study 32384397 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33579525 — Predictive Biomarker (PRD): AQP7 mRNA
Genes: AQP7; AQP7L; AQP9
Study 33579525 — Predictive Biomarker (PRD): AQP9 mRNA
Genes: AQP9; SSC1
Study 35729713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35370933 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35370933 — Surrogate Endpoint (SUR): Blood pressure
Study 34520637 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35164853 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35441926 — Surrogate Endpoint (SUR): Blood pressure
Study 34903034 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 32831984 — Surrogate Endpoint (SUR): Bone mineral density
Study 33528908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35997325 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34247100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34247100 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 32241790 — Predictive Biomarker (PRD): SLMAP mRNA
Genes: SLMAP; KIAA1601; SLAP; UNQ1847/PRO3577
Study 34805204 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 35477563 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32711957 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32711957 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32711957 — Predictive Biomarker (PRD): ENOSF1 mRNA
Genes: ENOSF1; RTS; TYMSAS
Study 32299355 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 32299355 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 32129194 — Surrogate Endpoint (SUR): Serum creatinine
Study 34755007 — Surrogate Endpoint (SUR): Bone mineral density
Study 35706006 — Safety Biomarker (SAF): Interleukin 1
Study 35706006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32885229 — Surrogate Endpoint (SUR): Blood pressure
Study 32885229 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32315869 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 34498307 — Surrogate Endpoint (SUR): Blood pressure
Study 34498307 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34498307 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32748473 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32748473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32748473 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 35628300 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 35628300 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 32468955 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35787693 — Surrogate Endpoint (SUR): Blood pressure
Study 33502237 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 32152377 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study 32152377 — Surrogate Endpoint (SUR): Total kidney volume
Study 36280113 — Predictive Biomarker (PRD): CPT1A mRNA
Genes: CPT1A; CPT1
Study 36280113 — Predictive Biomarker (PRD): CPT1B mRNA
Genes: CPT1B; KIAA1670
Study 35708431 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 35708431 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 35708431 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 32730797 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 35285531 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 36027483 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36027483 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 36027483 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 36027483 — Predictive Biomarker (PRD): FAM104B mRNA
Genes: FAM104B; CXorf44
Study 36027483 — Predictive Biomarker (PRD): KMT5A mRNA
Genes: KMT5A; PRSET7; SET07; SET8; SETD8
Study 36027483 — Predictive Biomarker (PRD): DNAH9 mRNA
Genes: DNAH9; DNAH17L; DNEL1; KIAA0357
Study 36027483 — Predictive Biomarker (PRD): UBXN11 mRNA
Genes: UBXN11; SOC; UBXD5; PP2243
Study 34639688 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 34035435 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33617653 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33617653 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 33617653 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33617653 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 33617653 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35235635 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 35235635 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 36151557 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 36151557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36151557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34020263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33452871 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 32107956 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-125b
Study 32654902 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 32000572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34631613 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 33029812 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 35131596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32757870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33735217 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 33735217 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 32471404 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 35471469 — Surrogate Endpoint (SUR): Serum creatinine
Study 35471469 — Surrogate Endpoint (SUR): Serum sodium
Study 34480575 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 32641376 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33799044 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 34528871 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34528871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34528871 — Safety Biomarker (SAF): BDNF
Study 36163873 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 35399553 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33485336 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33485336 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33485336 — Surrogate Endpoint (SUR): Blood pressure
Study 36288364 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 34554688 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 32146074 — Surrogate Endpoint (SUR): Blood pressure
Study 32233611 — Surrogate Endpoint (SUR): Blood pressure
Study 34506540 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 37757908 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 33559437 — Predictive Biomarker (PRD): PDPN mRNA
Genes: PDPN; GP36; PSEC0003; PSEC0025
Study 32723187 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study 35023260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33665904 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32305492 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 32441571 — Safety Biomarker (SAF): IL-6 and IL-10
Study 32641735 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 32043763 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32043763 — Predictive Biomarker (PRD): Hormone receptor
Study 36109036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32841219 — Predictive Biomarker (PRD): FCRL5 mRNA
Genes: FCRL5; FCRH5; IRTA2; UNQ503/PRO820
Study 34473033 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 32267714 — Surrogate Endpoint (SUR): Blood pressure
Study 33493256 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 35107141 — Surrogate Endpoint (SUR): Serum creatinine
Study 36178864 — Surrogate Endpoint (SUR): Blood pressure
Study 32512752 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32512752 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32379071 — Surrogate Endpoint (SUR): Blood pressure
Study 35420291 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 34402029 — Surrogate Endpoint (SUR): Blood pressure
Study 32721213 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34556320 — Surrogate Endpoint (SUR): Blood pressure
Study 33887120 — Surrogate Endpoint (SUR): Blood pressure
Study 32468646 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 35442755 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33504021 — Predictive Biomarker (PRD): ACTN3 mRNA
Genes: ACTN3
Study 36318852 — Predictive Biomarker (PRD): AZGP1 mRNA
Genes: AZGP1; ZAG; ZNGP1
Study 36318852 — Surrogate Endpoint (SUR): Sperm parameters
Study 32718191 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35798455 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 35341320 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 33487261 — Surrogate Endpoint (SUR): Blood pressure
Study 33580564 — Surrogate Endpoint (SUR): Blood pressure
Study 36413078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32066973 — Surrogate Endpoint (SUR): Blood pressure
Study 33226660 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33226660 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 34306265 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 34306265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34306265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32482534 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 32375440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32375440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32375440 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 32375440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33749997 — Safety Biomarker (SAF): Hyaluronic acid
Study 32593960 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 32912051 — Surrogate Endpoint (SUR): Blood pressure
Study 35565740 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 33113295 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 36394295 — Surrogate Endpoint (SUR): Blood pressure
Study 32469414 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 33522094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33522094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33976542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36921619 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 36921619 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36921619 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 33440080 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33299880 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 33299880 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 33299880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34580419 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34341833 — Surrogate Endpoint (SUR): Bone mineral density
Study 32654884 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 32240016 — Surrogate Endpoint (SUR): Blood pressure
Study 35624525 — Surrogate Endpoint (SUR): Blood pressure
Study 36382684 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 34108716 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35261318 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 32114709 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32114709 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34258509 — Surrogate Endpoint (SUR): Bone mineral density
Study 35549904 — Surrogate Endpoint (SUR): Blood pressure
Study 33793143 — Surrogate Endpoint (SUR): Blood pressure
Study 32115159 — Predictive Biomarker (PRD): PTBP2 mRNA
Genes: PTBP2; NPTB; PTB; PTBLP
Study 32862577 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32862577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32862577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32862577 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32862577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34371524 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 35582884 — Surrogate Endpoint (SUR): Blood pressure
Study 32418174 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 33125448 — Predictive Biomarker (PRD): TRO mRNA
Genes: TRO; KIAA1114; MAGED3
Study 36250434 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 33447937 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35354411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35354411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34331010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34331010 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33864831 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33864831 — Surrogate Endpoint (SUR): Blood pressure
Study 33000120 — Surrogate Endpoint (SUR): Urine free cortisol
Study 32077207 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 35149854 — Predictive Biomarker (PRD): Tubulin beta-3 chain
Genes: TUBB3; TUBB4
Study 35351406 — Monitoring Biomarker (MOI): Cell-free DNA
Study 34791973 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 33729664 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 33729664 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 33729664 — Surrogate Endpoint (SUR): Blood pressure
Study 33729664 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 33729664 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 33729664 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 33729664 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33208826 — Surrogate Endpoint (SUR): Blood pressure
Study 34910161 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 33784438 — Surrogate Endpoint (SUR): Bone mineral density
Study 32609230 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 33162512 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32997817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32997817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33383230 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33383230 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33383230 — Safety Biomarker (SAF): BDNF
Study 33383230 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34348526 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33468249 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 32385307 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34889733 — Surrogate Endpoint (SUR): Serum uric acid
Study 32503473 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 34139272 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34139272 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 34139272 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 34139272 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33108247 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 35422056 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 36380693 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 34470599 — Surrogate Endpoint (SUR): Serum calcium
Study 34470599 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 32485656 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 33498445 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 32208351 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 34818074 — Surrogate Endpoint (SUR): Blood pressure
Study 33664007 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33664007 — Surrogate Endpoint (SUR): Blood pressure
Study 36191882 — Surrogate Endpoint (SUR): Pathological complete response
Study 32251303 — Surrogate Endpoint (SUR): Serum creatinine
Study 34085505 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33612068 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32366163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32366163 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34028967 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 33677771 — Monitoring Biomarker (MOI): HBV DNA
Study 34749418 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 34749418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34749418 — Surrogate Endpoint (SUR): Blood pressure
Study 34910093 — Predictive Biomarker (PRD): FICD mRNA
Genes: FICD; HIP13; HYPE; UNQ3041/PRO9857
Study 34910093 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35421875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36155516 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU