TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05631795 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT02546739 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05429047 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05334342 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05545683 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06777303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06777303 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06777303 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT05720299 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04728841 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT06413238 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04974996 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT05460819 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04966975 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT05724641 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT05685225 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT04894253 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05370235 — Predictive Biomarker (PRD): XPC mRNA
Genes: XPC; XPCC
Study NCT05370235 — Predictive Biomarker (PRD): POLH mRNA
Genes: POLH; RAD30; RAD30A; XPV
Study NCT06332274 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05007236 — Predictive Biomarker (PRD): DHODH mRNA
Genes: DHODH
Study NCT05008679 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05008679 — Safety Biomarker (SAF): N-acetylneuraminic acid
Study NCT03745664 — Safety Biomarker (SAF): Cardiac troponin T
Genes: TNNT2
Study NCT00001072 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05786924 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05786924 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT05786924 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT05202561 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06669975 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05716932 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05716932 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06670599 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT06670599 — Safety Biomarker (SAF): Platelet to lymphocyte
Study NCT06630871 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06535620 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05465343 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05740943 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06262113 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT05373264 — Predictive Biomarker (PRD): AVPR2 mRNA
Genes: AVPR2; ADHR; DIR; DIR3; V2R
Study NCT06584045 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study NCT06584045 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study NCT06584045 — Predictive Biomarker (PRD): ADAM23 mRNA
Genes: ADAM23; MDC3
Study NCT06584045 — Predictive Biomarker (PRD): ADAM22 mRNA
Genes: ADAM22; MDC2
Study NCT04800146 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05226936 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04844268 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05512416 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05512416 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05680025 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05544994 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT05116904 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study NCT05450380 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05659563 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05659563 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04950270 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT04657406 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04335227 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT04717817 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT05675813 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT05761340 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06205498 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT06787625 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT05901935 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06787313 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT06221605 — Monitoring Biomarker (MOI): HBV DNA
Study NCT06785454 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06320223 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06272968 — Predictive Biomarker (PRD): EEF1A2 mRNA
Genes: EEF1A2; EEF1AL; STN
Study NCT05198934 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05881408 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT05881668 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05453929 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT04851041 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04557501 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06083376 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06083376 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05534594 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04921904 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04921904 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study NCT06389604 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05014594 — Surrogate Endpoint (SUR): Serum sodium
Study NCT06308939 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05113537 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05113537 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06159751 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT05311930 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT05020275 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05242172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05119322 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT05769075 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05769075 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT05769075 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT06529588 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study NCT05611021 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06486740 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05004493 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT06784648 — Predictive Biomarker (PRD): FCGR2B
Genes: CD32; CD32B; FcgammaRIIb; FcGRIIB
Study NCT05527418 — Predictive Biomarker (PRD): ITK mRNA
Genes: ITK; EMT; LYK
Study NCT06181734 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT05982886 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT05787418 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06784258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05882149 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06784557 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study NCT06088654 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT06323382 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06323382 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05504291 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study NCT06785597 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06237400 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06042647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06784921 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06649110 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT06649110 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT06722651 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05274269 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT05159115 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study NCT06757647 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT06783140 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06783140 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT06784440 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT06784791 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06784817 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT06786819 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT06786260 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study NCT06786260 — Surrogate Endpoint (SUR): Total kidney volume
Study NCT06783296 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06785519 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06785519 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06786234 — Predictive Biomarker (PRD): CTPS1 mRNA
Genes: CTPS1; CTPS
Study NCT06783907 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04709536 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06089226 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06007092 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT06353984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06353984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06353984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05416580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05416580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05416580 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT05416580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05416580 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT05824962 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT06174129 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06464341 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT06308692 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study NCT05039944 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study NCT05893381 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05777135 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05236257 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT04203004 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04203004 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04203004 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT06670820 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06670820 — Safety Biomarker (SAF): BDNF
Study NCT05601973 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05903144 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05367544 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06138574 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05942846 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT05510570 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT05535413 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05460143 — Safety Biomarker (SAF): Cytochrome c
Study NCT04852081 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04852081 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04852081 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06178770 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06178770 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05384509 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05384509 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04664478 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study NCT04664478 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study NCT04664478 — Predictive Biomarker (PRD): MFAP4 mRNA
Genes: MFAP4
Study NCT04664478 — Predictive Biomarker (PRD): FBLN5 mRNA
Genes: FBLN5; DANCE; UNQ184/PRO210
Study NCT04664478 — Predictive Biomarker (PRD): EFEMP2 mRNA
Genes: EFEMP2; FBLN4; UNQ200/PRO226
Study NCT05986045 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT06143241 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study NCT06143241 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT05972720 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT05464849 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05498519 — Predictive Biomarker (PRD): FGFR4 mRNA
Genes: FGFR4; JTK2; TKF
Study NCT04797858 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05335200 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05486533 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05148806 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06082050 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT05912296 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study NCT05912296 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT05017740 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05174169 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06035133 — Predictive Biomarker (PRD): TNNT1 mRNA
Genes: TNNT1; TNT
Study NCT05950919 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05302648 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06111781 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT05879250 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT05768165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05350644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04683003 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT04683003 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT06573606 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT05444270 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT05191472 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT06635330 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06577532 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04298541 — Predictive Biomarker (PRD): SSTR2 mRNA
Genes: SSTR2
Study NCT04842955 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05284994 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05522257 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05518357 — Predictive Biomarker (PRD): LILRB4 mRNA
Genes: LILRB4; ILT3; LIR5
Study NCT06149078 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT05822180 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04814147 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT05905367 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study NCT05101746 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT05101746 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT05132218 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04643444 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06155708 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04892017 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study NCT04437290 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06364462 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06360289 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT05385003 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT06777108 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05170412 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06008522 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05588479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05588479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05588479 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05588479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05588479 — Safety Biomarker (SAF): Interleukin 1
Study NCT06704724 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06725576 — Predictive Biomarker (PRD): Protein patched homolog 1
Genes: PTCH1; PTCH
Study NCT00001094 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04163614 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04047836 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04713956 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03607955 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT05331521 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT06448624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05796570 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06009055 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06457711 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06784778 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06357182 — Predictive Biomarker (PRD): KDM1A mRNA
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study NCT06552234 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT05607719 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT05097287 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06785584 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT06787404 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06787001 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01885676 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT06787482 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT06787482 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06783517 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05296798 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05296798 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05296798 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06780592 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT06776172 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06499519 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT05490576 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04872595 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT06576102 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06015854 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia