TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33246489 — Predictive Biomarker (PRD): TNC mRNA
Genes: TNC; HXB
Study 33246489 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 34034036 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 34034036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32720695 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 36075073 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 36075073 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33301613 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 33301613 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33499376 — Surrogate Endpoint (SUR): Blood pressure
Study 35247102 — Surrogate Endpoint (SUR): Blood pressure
Study 34551146 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33384892 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 32905628 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 32905628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32905628 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33065070 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 34768411 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 35976136 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33765679 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 35235082 — Surrogate Endpoint (SUR): Blood pressure
Study 35894434 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 32065620 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 32065620 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 32065620 — Surrogate Endpoint (SUR): Blood pressure
Study 33530942 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 32902312 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 35973802 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 35663978 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35663978 — Surrogate Endpoint (SUR): Pathological complete response
Study 35274092 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 33726766 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33600014 — Surrogate Endpoint (SUR): Blood pressure
Study 34669318 — Surrogate Endpoint (SUR): Serum calcium
Study 33185380 — Predictive Biomarker (PRD): PIR mRNA
Genes: PIR
Study 35607454 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35607454 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 33142541 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33639233 — Surrogate Endpoint (SUR): Blood pressure
Study 32812324 — Surrogate Endpoint (SUR): Blood pressure
Study 32812324 — Surrogate Endpoint (SUR): Serum potassium
Study 34213493 — Surrogate Endpoint (SUR): Blood pressure
Study 32942770 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34541479 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 34541479 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 34541479 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 32505177 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32220771 — Surrogate Endpoint (SUR): Serum creatinine
Study 33145441 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33145441 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 32513289 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32513289 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 32753750 — Predictive Biomarker (PRD): RGS1 mRNA
Genes: RGS1; 1R20; BL34; IER1
Study 32753750 — Predictive Biomarker (PRD): SMC4 mRNA
Genes: SMC4; CAPC; SMC4L1
Study 35970431 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 34031020 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 32383748 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32383748 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 32383748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34208363 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 34208363 — Predictive Biomarker (PRD): TFAP2B mRNA
Genes: TFAP2B
Study 34208363 — Predictive Biomarker (PRD): PLIN1 mRNA
Genes: PLIN1; PERI; PLIN
Study 35790961 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33406277 — Predictive Biomarker (PRD): ACKR3 mRNA
Genes: ACKR3; CMKOR1; CXCR7; GPR159; RDC1
Study 33406277 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 33406277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 35995732 — Surrogate Endpoint (SUR): Blood pressure
Study 33214579 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 34269720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32035892 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32686253 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 32686253 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 36484191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33190133 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 33933206 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33351885 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 33351885 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 33351885 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 33351885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35544387 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32142135 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 33028352 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33028352 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33612706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35939578 — Pharmacodynamic Biomarker (PDY): C-type lectin domain family 4 member C
Genes: CLEC4C; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; UNQ9361/PRO34150
Study 36162889 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 35481691 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 33906292 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 34858175 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32028085 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 34772437 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 32779057 — Surrogate Endpoint (SUR): Serum potassium
Study 33538655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33538655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32439823 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 32148225 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35255530 — Surrogate Endpoint (SUR): Blood pressure
Study 32940090 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33706066 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 35483678 — Surrogate Endpoint (SUR): Blood pressure
Study 34503349 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32782904 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study 34151843 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 36066725 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35353979 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35311524 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 32144522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32144522 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 32144522 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33348420 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 33348420 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 34448003 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34448003 — Surrogate Endpoint (SUR): Blood pressure
Study 34448003 — Surrogate Endpoint (SUR): Serum sodium
Study 33740099 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 33740099 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 33952669 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 34225200 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34225200 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 34706171 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 34706171 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 32591862 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 32591862 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study 32591862 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 32591862 — Predictive Biomarker (PRD): STAT2 mRNA
Genes: STAT2
Study 32591862 — Predictive Biomarker (PRD): TPSAB1 mRNA
Genes: TPSAB1; TPS1; TPS2; TPSB1
Study 32591862 — Predictive Biomarker (PRD): CD9 mRNA
Genes: CD9; MIC3; TSPAN29; GIG2
Study 32591862 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 32361863 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 35383463 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32779386 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 32732928 — Surrogate Endpoint (SUR): Serum creatinine
Study 32526634 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 35226357 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32218418 — Safety Biomarker (SAF): Reactive oxygen species
Study 32218418 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 32218418 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 35897081 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 36253609 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32216086 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 32216086 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 35387813 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35387813 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33617937 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33617937 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33617937 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 33617937 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 33617937 — Predictive Biomarker (PRD): Hormone receptor
Study 32537688 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 36117491 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 36117491 — Surrogate Endpoint (SUR): Blood pressure
Study 36117491 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36117491 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34154588 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 34154588 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 34037436 — Surrogate Endpoint (SUR): Blood pressure
Study 33884504 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 32107364 — Surrogate Endpoint (SUR): Serum creatinine
Study 36321877 — Surrogate Endpoint (SUR): Probing pocket depth
Study 35355382 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34003273 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 33103934 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 34015499 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34015499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35177279 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 35091786 — Surrogate Endpoint (SUR): Blood pressure
Study 32458096 — Surrogate Endpoint (SUR): Bone mineral density
Study 33100181 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 33825687 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 32633067 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 35255096 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study 34006388 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 34006388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35093682 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35093682 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32349193 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 34263442 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 36464887 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 33160420 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 33160420 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 35115099 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 34462278 — Surrogate Endpoint (SUR): Blood pressure
Study 32220893 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32220893 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 32220893 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 32220893 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 33186735 — Surrogate Endpoint (SUR): Blood pressure
Study 35462552 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35462552 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35462552 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 33284944 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study 33284944 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 34143220 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 34769797 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34769797 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32203207 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32289283 — Predictive Biomarker (PRD): HSPA1A mRNA
Genes: HSPA1A; HSP72; HSPA1; HSX70
Study 32289283 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 32289283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33485455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33485455 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 33738615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33738615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36102618 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 32869576 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 35675149 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33599720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32232971 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 35701314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32747206 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 34959932 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33278328 — Surrogate Endpoint (SUR): Serum asparaginase
Study 32668483 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 32603956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35030255 — Surrogate Endpoint (SUR): Platelet count response
Study 34210725 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 32061969 — Surrogate Endpoint (SUR): Blood pressure
Study 32061969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35636031 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 36357559 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 33149205 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 36361100 — Surrogate Endpoint (SUR): Blood pressure
Study 34933842 — Safety Biomarker (SAF): Hyaluronic acid
Study 36049647 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 34791761 — Surrogate Endpoint (SUR): Blood pressure
Study 34910825 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33660386 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33660386 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 36031405 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 35177687 — Surrogate Endpoint (SUR): Blood pressure
Study 32270927 — Surrogate Endpoint (SUR): Blood pressure
Study 34850043 — Predictive Biomarker (PRD): Hormone receptor
Study 34272817 — Surrogate Endpoint (SUR): Blood pressure
Study 36180564 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 36180564 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 36180564 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 36180564 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35956364 — Surrogate Endpoint (SUR): Blood pressure
Study 33607831 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34564893 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34686472 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 32469156 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32469156 — Surrogate Endpoint (SUR): Serum creatinine
Study 35986303 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 33453159 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 33401126 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35848047 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33303340 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 33303340 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 33387724 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33387724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33387724 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35621697 — Safety Biomarker (SAF): HLA-DQA1
Genes: CELIAC1
Study 36006643 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study 36006643 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 36293723 — Surrogate Endpoint (SUR): Blood pressure
Study 34351939 — Surrogate Endpoint (SUR): Blood pressure
Study 35513777 — Surrogate Endpoint (SUR): Blood pressure
Study 32869151 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 33715235 — Surrogate Endpoint (SUR): Blood pressure
Study 33275596 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33275596 — Surrogate Endpoint (SUR): Blood pressure
Study 33521870 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33521870 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33032658 — Surrogate Endpoint (SUR): Serum creatinine
Study 35147085 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35147085 — Surrogate Endpoint (SUR): Blood pressure
Study 34813098 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33210302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33210302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35279081 — Surrogate Endpoint (SUR): Sputum culture conversion to negative
Study 32764524 — Surrogate Endpoint (SUR): Blood pressure
Study 34425554 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 32043762 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32043762 — Predictive Biomarker (PRD): Hormone receptor
Study 36286977 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 34454754 — Predictive Biomarker (PRD): TJP1 mRNA
Genes: TJP1; ZO1
Study 34454754 — Predictive Biomarker (PRD): CLDN2 mRNA
Genes: CLDN2; PSEC0059; SP82; UNQ705/PRO1356
Study 34454754 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 32915962 — Surrogate Endpoint (SUR): Blood pressure
Study 36093398 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP