TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04778579 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05307705 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT05986162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05149846 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT04771520 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study NCT05314192 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT05314192 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study NCT05314192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06271252 — Predictive Biomarker (PRD): GPRC5D mRNA
Genes: GPRC5D
Study NCT06064890 — Predictive Biomarker (PRD): GRN mRNA
Genes: GRN
Study NCT06152042 — Predictive Biomarker (PRD): BMF mRNA
Genes: BMF
Study NCT05363384 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05052099 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05052099 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05052099 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06195059 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00002173 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03114228 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT06509997 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT05072561 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT05595915 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study NCT04538144 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06391736 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT04892043 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT06163950 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT05987605 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05947682 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05278078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00002091 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06014541 — Predictive Biomarker (PRD): MECP2 mRNA
Genes: MECP2
Study NCT05397665 — Predictive Biomarker (PRD): SORD mRNA
Genes: SORD
Study NCT05372328 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06478537 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT05771506 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06282536 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05128786 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT05311176 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05740631 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT05982639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05870319 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05870319 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06528522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05190315 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study NCT06066840 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT00002007 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00002007 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04669587 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04923503 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT05243368 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT06462365 — Predictive Biomarker (PRD): TXN mRNA
Genes: TXN; TRDX; TRX; TRX1
Study NCT05546931 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06406192 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05851859 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05092685 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study NCT06316752 — Predictive Biomarker (PRD): NEU1 mRNA
Genes: NEU1; NANH
Study NCT06334731 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05397054 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05020392 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05020392 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT06054152 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study NCT04771546 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02500784 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05228145 — Predictive Biomarker (PRD): CLN5 mRNA
Genes: CLN5
Study NCT05034107 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04898127 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06349850 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT06349850 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05678270 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT05376527 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05843305 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study NCT05837325 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT06396455 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05359588 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT05359588 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05145803 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04742972 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06388135 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05500560 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04641910 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04641910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04641910 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT04641910 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT04725539 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05477017 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05983042 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT05680818 — Predictive Biomarker (PRD): ADH1A mRNA
Genes: ADH1A; ADH1
Study NCT04501757 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05954260 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study NCT04651439 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06177171 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06177171 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT06177171 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT06177171 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study NCT05552807 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study NCT06248463 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05659628 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05659628 — Safety Biomarker (SAF): C-C motif chemokine 19
Genes: CCL19; ELC; MIP3B; SCYA19
Study NCT05223699 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study NCT00001036 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00001036 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05116891 — Predictive Biomarker (PRD): IL1RAP mRNA
Genes: IL1RAP; C3orf13; IL1R3
Study NCT05742841 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05477446 — Predictive Biomarker (PRD): CD207 mRNA
Genes: CD207; CLEC4K
Study NCT05685719 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04874844 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT04874844 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04858503 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06268483 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT06268483 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00172562 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00172562 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study NCT00172562 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05786534 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05134597 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06158282 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06043245 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT06043245 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT05996679 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT04840368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04840368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04840368 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04840368 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05167188 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05462340 — Predictive Biomarker (PRD): CHRNA7 mRNA
Genes: CHRNA7; NACHRA7
Study NCT05117593 — Predictive Biomarker (PRD): FBL mRNA
Genes: FBL; FIB1; FLRN
Study NCT06449989 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06449989 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT06449989 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05218304 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05228080 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05228080 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05228080 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT05141357 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06014957 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04698681 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study NCT04698681 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05779800 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06383000 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04743674 — Monitoring Biomarker (MOI): Circulating tumor HPV DNA
Study NCT05854797 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04679389 — Predictive Biomarker (PRD): PMM2 mRNA
Genes: PMM2
Study NCT04679389 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT04679389 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06050577 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06126406 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04777123 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05984407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05984407 — Safety Biomarker (SAF): Interleukin 1
Study NCT05984407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05550389 — Predictive Biomarker (PRD): BMPR2 mRNA
Genes: BMPR2; PPH1
Study NCT05488418 — Predictive Biomarker (PRD): ELK1 mRNA
Genes: ELK1
Study NCT06507332 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05950555 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT05950555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05137275 — Predictive Biomarker (PRD): TPBG mRNA
Genes: TPBG; 5T4
Study NCT05054231 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT06261476 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05135585 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05013294 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05013294 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06122246 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05581355 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05878691 — Predictive Biomarker (PRD): MAP4K1 mRNA
Genes: MAP4K1; HPK1
Study NCT04705987 — Safety Biomarker (SAF): Interleukin 1
Study NCT04720339 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT06372613 — Predictive Biomarker (PRD): Leucine-rich alpha-2-glycoprotein
Genes: LRG1; LRG
Study NCT05481892 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05338190 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT05428449 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT06047067 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05824767 — Predictive Biomarker (PRD): DPP3 mRNA
Genes: DPP3
Study NCT05824767 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT05825092 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT05022472 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05543824 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04770298 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT06512831 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT05944913 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT05228756 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06572787 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT05215808 — Predictive Biomarker (PRD): PARP14 mRNA
Genes: PARP14; BAL2; KIAA1268
Study NCT05000411 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT04859218 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT01869803 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT06146088 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05818137 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT05818137 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT05603494 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT05603494 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT01674738 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT01674738 — Predictive Biomarker (PRD): TYMS
Genes: Tsase; TMS; HsT422
Study NCT06434025 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT04949828 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT06238011 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05358184 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05591651 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05493501 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05493501 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05078671 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT05078671 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05078671 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04904315 — Predictive Biomarker (PRD): TTLL5 mRNA
Genes: TTLL5; KIAA0998; STAMP
Study NCT04360772 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study NCT05321693 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05321693 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT05321693 — Safety Biomarker (SAF): BDNF
Study NCT05685394 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06380348 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05834699 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06068569 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06462430 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT05784870 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT05784870 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT05784870 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06538831 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05598203 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05570513 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT05094804 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study NCT05250518 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT06086236 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06114511 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04148716 — Safety Biomarker (SAF): miR-214
Genes: MIR214
Study NCT05389514 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05389514 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study NCT05716152 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT05600998 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05065164 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06090539 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study NCT05834400 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05135429 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05326074 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT05326074 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04885764 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05004688 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05487742 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05283213 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT05283213 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT05283213 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT05283213 — Predictive Biomarker (PRD): DKK3 mRNA
Genes: DKK3; REIC; UNQ258/PRO295
Study NCT05283213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05283213 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT04491084 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT04491084 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT06550297 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06647290 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study NCT06125639 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06414135 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06650748 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06650748 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06650748 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT06657391 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT06658548 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06587334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06587334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06608550 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06604767 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05151445 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04085653 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT03770299 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05451056 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04703270 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05359874 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04452331 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05033587 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT05720689 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04887610 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05439993 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05659017 — Predictive Biomarker (PRD): FTL mRNA
Genes: FTL
Study NCT05659017 — Predictive Biomarker (PRD): STAB1 mRNA
Genes: STAB1; FEEL1; KIAA0246
Study NCT05760131 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06478056 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05930002 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04965090 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06646705 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT05961618 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05129280 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A