TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33272291 — Safety Biomarker (SAF): IL-6 and IL-10
Study 32995892 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 35165297 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 35005202 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 33389320 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32525464 — Surrogate Endpoint (SUR): Blood pressure
Study 34125340 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32867954 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 32867954 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32867954 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 32867954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 32867954 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32867954 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 32867954 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 32867954 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 32867954 — Safety Biomarker (SAF): Reactive oxygen species
Study 34665890 — Surrogate Endpoint (SUR): Blood pressure
Study 33358401 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35213213 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 34726958 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32891163 — Safety Biomarker (SAF): Reactive oxygen species
Study 32891163 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32969580 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 36267499 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 36267499 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34190954 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35768818 — Surrogate Endpoint (SUR): Blood pressure
Study 36145254 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34241685 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 33755728 — Surrogate Endpoint (SUR): Blood pressure
Study 36414827 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35940829 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 34922298 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33430772 — Surrogate Endpoint (SUR): Blood pressure
Study 32061400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35428982 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32337698 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35057416 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 32415981 — Surrogate Endpoint (SUR): Serum creatinine
Study 32415981 — Surrogate Endpoint (SUR): Serum sodium
Study 32397850 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32397850 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34905152 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 35672690 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 34070315 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32030417 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35795100 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35795100 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 35795100 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32350909 — Predictive Biomarker (PRD): TRAF3 mRNA
Genes: TRAF3; CAP-1; CRAF1; TRAFAMN
Study 32350909 — Predictive Biomarker (PRD): BIRC2 mRNA
Genes: BIRC2; API1; MIHB; RNF48
Study 32350909 — Predictive Biomarker (PRD): MAP3K14 mRNA
Genes: MAP3K14; NIK
Study 32141365 — Surrogate Endpoint (SUR): Blood pressure
Study 35084480 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 36088650 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study 32457083 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 33704494 — Surrogate Endpoint (SUR): Blood pressure
Study 36176768 — Surrogate Endpoint (SUR): Blood pressure
Study 35299968 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 35299968 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36226244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36226244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33026636 — Predictive Biomarker (PRD): KIAA1549 mRNA
Genes: KIAA1549
Study 33026636 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 33047216 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 33047216 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 33231313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33231313 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35480138 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35480138 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35900305 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 32016500 — Predictive Biomarker (PRD): INVS mRNA
Genes: INVS; INV; NPHP2
Study 36251422 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 35763114 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 34560015 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 32863275 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 32366280 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 36031789 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 33920232 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 33223487 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33823461 — Surrogate Endpoint (SUR): Blood pressure
Study 34676656 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 32875421 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 36192924 — Safety Biomarker (SAF): Bacteroidetes phylum
Study 33302675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33165879 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 33165879 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33165879 — Surrogate Endpoint (SUR): Blood pressure
Study 35210504 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33017219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33677616 — Surrogate Endpoint (SUR): Serum creatinine
Study 33677616 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 35751421 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 32862713 — Surrogate Endpoint (SUR): Blood pressure
Study 37721178 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34450475 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 33175279 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 34550084 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 34550084 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 33165503 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 35597980 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36335976 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33252440 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 32974752 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32785210 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32487131 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35088708 — Surrogate Endpoint (SUR): Blood pressure
Study 35088708 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32701144 — Surrogate Endpoint (SUR): Blood pressure
Study 36368749 — Safety Biomarker (SAF): Human leucocyte antigen
Study 36014843 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 36014843 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33734121 — Surrogate Endpoint (SUR): Blood pressure
Study 33594404 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 33594404 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34015116 — Surrogate Endpoint (SUR): Blood pressure
Study 35998848 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 32851483 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 32851483 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32851483 — Surrogate Endpoint (SUR): Blood pressure
Study 34188004 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34188004 — Surrogate Endpoint (SUR): Blood pressure
Study 36463643 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36463643 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36463643 — Predictive Biomarker (PRD): Hormone receptor
Study 32773651 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32773651 — Surrogate Endpoint (SUR): Blood pressure
Study 34711333 — Surrogate Endpoint (SUR): Blood pressure
Study 33823163 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34196787 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study 33464924 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 33792623 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 33980763 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 33980763 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32729843 — Surrogate Endpoint (SUR): Blood pressure
Study 33591469 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33880760 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 32290859 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 32111521 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 32111521 — Predictive Biomarker (PRD): SELENOP mRNA
Genes: SELENOP; SELP; SEPP1
Study 32111521 — Predictive Biomarker (PRD): SELENON mRNA
Genes: SELENON; SELN; SEPN1
Study 32111521 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33217092 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33685306 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32641747 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34674574 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 35465804 — Surrogate Endpoint (SUR): Blood pressure
Study 33006190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34757919 — Predictive Biomarker (PRD): PM20D1 mRNA
Genes: PM20D1
Study 34757919 — Predictive Biomarker (PRD): NAAA mRNA
Genes: NAAA; ASAHL; PLT
Study 34757919 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study 35039263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35039263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34475873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35853017 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 34427452 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 35894080 — Predictive Biomarker (PRD): GLP1R mRNA
Genes: GLP1R
Study 35894080 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 32061188 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 35407385 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 32272022 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study 33186325 — Surrogate Endpoint (SUR): Blood pressure
Study 33186325 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34486579 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 33752439 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 34758350 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 33427183 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33427183 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34478124 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 34478124 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 34478124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32559052 — Surrogate Endpoint (SUR): Bone mineral density
Study 33067703 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 33067703 — Monitoring Biomarker (MOI): Cell-free DNA
Study 33941150 — Surrogate Endpoint (SUR): Bone mineral density
Study 35522237 — Predictive Biomarker (PRD): SQSTM1 mRNA
Genes: SQSTM1; ORCA; OSIL
Study 35274723 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36104012 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 32939893 — Predictive Biomarker (PRD): PHC1 mRNA
Genes: PHC1; EDR1; PH1
Study 32939893 — Predictive Biomarker (PRD): PHC3 mRNA
Genes: PHC3; EDR3; PH3
Study 32923335 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 35765103 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35765103 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33176886 — Surrogate Endpoint (SUR): Serum creatinine
Study 33176886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33176886 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35485381 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 33424840 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study 32073648 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 32073648 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35556023 — Surrogate Endpoint (SUR): Blood pressure
Study 34334431 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 32132105 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 32132105 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 32132105 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 34316017 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 34521933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34521933 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 34521933 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 34521933 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 34521933 — Predictive Biomarker (PRD): DEFB4A mRNA
Genes: DEFB4A; DEFB102; DEFB2; DEFB4; DEFB4B
Study 34521933 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 34521933 — Predictive Biomarker (PRD): S100A7 mRNA
Genes: S100A7; PSOR1; S100A7C
Study 34521933 — Predictive Biomarker (PRD): Calgranulin B
Genes: S100A9; CAGB; CFAG; MRP14
Study 34521933 — Predictive Biomarker (PRD): TFEB mRNA
Genes: TFEB; BHLHE35
Study 36206498 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 36206498 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36206498 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 36075242 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32722819 — Predictive Biomarker (PRD): HNF1A mRNA
Genes: HNF1A; TCF1
Study 32722819 — Predictive Biomarker (PRD): HNF4A mRNA
Genes: HNF4A; HNF4; NR2A1; TCF14
Study 32379240 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33237938 — Surrogate Endpoint (SUR): Blood pressure
Study 34605077 — Predictive Biomarker (PRD): PDPN mRNA
Genes: PDPN; GP36; PSEC0003; PSEC0025
Study 34972100 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33138797 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33138797 — Predictive Biomarker (PRD): FCER1A mRNA
Genes: FCER1A; FCE1A
Study 33138797 — Predictive Biomarker (PRD): EDNRB mRNA
Genes: EDNRB; ETRB
Study 33138797 — Predictive Biomarker (PRD): TGFBI mRNA
Genes: TGFBI; BIGH3
Study 32035552 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 32035552 — Predictive Biomarker (PRD): IL17F
Genes: IL-17F; ML-1; ML1
Study 33284116 — Surrogate Endpoint (SUR): Blood pressure
Study 34775781 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 34775781 — Surrogate Endpoint (SUR): Blood pressure
Study 34775781 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34420102 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 33786980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33786980 — Monitoring Biomarker (MOI): Procalcitonin
Study 33786980 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32885526 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 32885526 — Predictive Biomarker (PRD): LEPROT mRNA
Genes: LEPROT; LEPR; OBR
Study 32885526 — Surrogate Endpoint (SUR): Blood pressure
Study 32885526 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35286526 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 36071224 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 35689598 — Predictive Biomarker (PRD): CHAD mRNA
Genes: CHAD; SLRR4A
Study 33971853 — Surrogate Endpoint (SUR): Serum creatinine
Study 34204618 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34204618 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34204618 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33374524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33374524 — Surrogate Endpoint (SUR): Blood pressure
Study 33374524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35891905 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32172239 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32172239 — Surrogate Endpoint (SUR): Serum creatinine
Study 34283844 — Surrogate Endpoint (SUR): Blood pressure
Study 34156639 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32459282 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 33927790 — Surrogate Endpoint (SUR): Blood pressure
Study 32729954 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 34277982 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 35538139 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34902004 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 35414801 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33974559 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33451627 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 33451627 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 33451627 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 33451627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33451627 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 33451627 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 33451627 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 33451627 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 33451627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32046665 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34863879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34863879 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34034268 — Surrogate Endpoint (SUR): Serum creatinine
Study 33872448 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 35505620 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 34255042 — Predictive Biomarker (PRD): CYP3A7 mRNA
Genes: CYP3A7