TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32516291 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 36377016 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33413320 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33390421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33390421 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35147302 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 36455504 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 36352326 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33452295 — Predictive Biomarker (PRD): MLIP mRNA
Genes: MLIP; C6orf142; Cip
Study 32937008 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32937008 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 34028647 — Surrogate Endpoint (SUR): Serum potassium
Study 34028647 — Surrogate Endpoint (SUR): Serum calcium
Study 33947390 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 33054635 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 34629300 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 34629300 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33688928 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33186897 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33725433 — Safety Biomarker (SAF): Reactive oxygen species
Study 33966407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32492988 — Predictive Biomarker (PRD): EVC mRNA
Genes: EVC
Study 33557578 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33557578 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33557578 — Surrogate Endpoint (SUR): Blood pressure
Study 35984107 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35474007 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 32455486 — Predictive Biomarker (PRD): MC1R mRNA
Genes: MC1R; MSHR
Study 32455486 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 33416271 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33416271 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33211738 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 35733163 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35733163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35733163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35733163 — Predictive Biomarker (PRD): MAPK1 mRNA
Genes: MAPK1; ERK2; PRKM1; PRKM2
Study 35733163 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 35733163 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35733163 — Safety Biomarker (SAF): Interleukin 1
Study 35733163 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 34314347 — Surrogate Endpoint (SUR): Blood pressure
Study 36233611 — Surrogate Endpoint (SUR): Blood pressure
Study 36233611 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35985477 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 33729273 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 36471982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36471982 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33934471 — Predictive Biomarker (PRD): ODC1 mRNA
Genes: ODC1
Study 34516703 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33127531 — Surrogate Endpoint (SUR): Blood pressure
Study 35298917 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 35298917 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 36006011 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 35046058 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 35532908 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34588198 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35933275 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32598699 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 34379277 — Surrogate Endpoint (SUR): Blood pressure
Study 32329160 — Surrogate Endpoint (SUR): Blood pressure
Study 36165603 — Surrogate Endpoint (SUR): Serum testosterone
Study 32554736 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 35373947 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 32019814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 33079901 — Surrogate Endpoint (SUR): Bone mineral density
Study 32916273 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 32916273 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 34958809 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33278031 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 32509290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32446323 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32446323 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34039390 — Surrogate Endpoint (SUR): Blood pressure
Study 34920045 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32256020 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 32256020 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 32256020 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 33219694 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33219694 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 34255767 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35768786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 35768786 — Surrogate Endpoint (SUR): Blood pressure
Study 34113085 — Surrogate Endpoint (SUR): Blood pressure
Study 33203618 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33291229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33985991 — Surrogate Endpoint (SUR): Urinary oxalate
Study 35708715 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32967883 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 32074702 — Surrogate Endpoint (SUR): Blood pressure
Study 35419116 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 33545764 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33545764 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33648623 — Surrogate Endpoint (SUR): Blood pressure
Study 32517755 — Surrogate Endpoint (SUR): Bone mineral density
Study 35589854 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 35589854 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Interleukin 6 receptor alpha
Genes: IL6R
Study 35083924 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 35083924 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 34626838 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34147123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32456230 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 32456230 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35986358 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 33228827 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34718403 — Surrogate Endpoint (SUR): Blood pressure
Study 36035830 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 32142371 — Surrogate Endpoint (SUR): Blood pressure
Study 35264321 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 36402666 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 33236115 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 32544082 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 34582903 — Surrogate Endpoint (SUR): Blood pressure
Study 35553816 — Predictive Biomarker (PRD): TCF7 mRNA
Genes: TCF7; TCF1
Study 35553816 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35553816 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study 34961542 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 35922472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33356421 — Predictive Biomarker (PRD): Microsatellite instability
Study 35249510 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 32919015 — Predictive Biomarker (PRD): SIRT3 mRNA
Genes: SIRT3; SIR2L3
Study 32919015 — Predictive Biomarker (PRD): SIRT6 mRNA
Genes: SIRT6; SIR2L6
Study 32919015 — Predictive Biomarker (PRD): PPARGC1B mRNA
Genes: PPARGC1B; PERC; PGC1; PGC1B; PPARGC1
Study 34719872 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34776002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34776002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34776002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33216421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33321380 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35562327 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34271122 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study 34271122 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 35254433 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35254433 — Surrogate Endpoint (SUR): Blood pressure
Study 34127029 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 35228490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35228490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35228490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34128838 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 35019238 — Predictive Biomarker (PRD): EIF2AK2 mRNA
Genes: EIF2AK2; PKR; PRKR
Study 33895682 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 32721578 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34036355 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 34036355 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 35798633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35798633 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 33464703 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 35418091 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 35418091 — Surrogate Endpoint (SUR): Blood pressure
Study 33362392 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32182310 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 32182310 — Predictive Biomarker (PRD): DGAT1 mRNA
Genes: DGAT1; AGRP1; DGAT
Study 32182310 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 32182310 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 32182310 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 32182310 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32182310 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32064499 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 34120448 — Surrogate Endpoint (SUR): Blood pressure
Study 32589229 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32046415 — Predictive Biomarker (PRD): NAV3 mRNA
Genes: NAV3; KIAA0938; POMFIL1; STEERIN3
Study 32240476 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 32167484 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32167484 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33150816 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 36233791 — Predictive Biomarker (PRD): VCP mRNA
Genes: VCP
Study 34050763 — Surrogate Endpoint (SUR): Serum testosterone
Study 32416251 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 32416251 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 32416251 — Predictive Biomarker (PRD): Hormone receptor
Study 32416251 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 35834812 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33809062 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 33809062 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 32865010 — Surrogate Endpoint (SUR): Blood pressure
Study 32865010 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 35533340 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 32948386 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 33795621 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 34167878 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34167878 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34280356 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33152708 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 33152708 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 36239563 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36239563 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32657670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32489001 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 35840352 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 36262203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33947363 — Surrogate Endpoint (SUR): Bone mineral density
Study 32178928 — Surrogate Endpoint (SUR): Serum creatinine
Study 33742783 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 35879015 — Surrogate Endpoint (SUR): Blood pressure
Study 35938229 — Predictive Biomarker (PRD): NFIC mRNA
Genes: NFIC; NFI
Study 34368187 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 33046128 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 33766814 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 36154103 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32639518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33966115 — Predictive Biomarker (PRD): DARS1 mRNA
Genes: DARS1; DARS; PIG40
Study 32162804 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32162804 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 33846498 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 33846498 — Safety Biomarker (SAF): Interleukin 1
Study 33846498 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33038014 — Predictive Biomarker (PRD): IVNS1ABP mRNA
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 34768274 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 33856733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33856733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33856733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34592164 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32331005 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32797473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32579785 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 36058950 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34932104 — Surrogate Endpoint (SUR): Blood pressure
Study 34036613 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 35632774 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34287644 — Surrogate Endpoint (SUR): Blood pressure
Study 34613513 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 34310432 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 616850836 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 616850836 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 36382431 — Surrogate Endpoint (SUR): Blood pressure
Study 34585554 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34585554 — Surrogate Endpoint (SUR): Blood pressure
Study 34330312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34330312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34330312 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 34330312 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35785538 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 32759258 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34976813 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35844809 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 35982781 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34181876 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 32469182 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35272017 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 35272017 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32620335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32620335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32620335 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33926511 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33926511 — Safety Biomarker (SAF): BDNF
Study 36244364 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 32045540 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35893914 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 34116206 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35836924 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 34456042 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32078436 — Safety Biomarker (SAF): Cytochrome c
Study 36194164 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 33038018 — Predictive Biomarker (PRD): HLF mRNA
Genes: HLF
Study 32671719 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32671719 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 32671719 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 32671719 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32451161 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32196749 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 35400328 — Surrogate Endpoint (SUR): Blood pressure
Study 35400328 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32331018 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC18A2 mRNA
Genes: SLC18A2; SVMT; VMAT2
Study 33768777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33201347 — Predictive Biomarker (PRD): CYP51A1 mRNA
Genes: CYP51A1; CYP51
Study 33201347 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 32066625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1