TrialPanorama/TrialPanorama-database huggingface dataset:
Study 34862643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35661214 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 35661214 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study 35661214 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 34796837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34796837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34796837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34796837 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 34796837 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 34796837 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 34796837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 34796837 — Safety Biomarker (SAF): C-X-C motif chemokine 5
Genes: CXCL5; ENA78; SCYB5
Study 34796837 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 33068146 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35549460 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 33076805 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 33076805 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 34581765 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 34581765 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 34581765 — Surrogate Endpoint (SUR): Bone mineral density
Study 34921497 — Surrogate Endpoint (SUR): Blood pressure
Study 32687296 — Surrogate Endpoint (SUR): Blood pressure
Study 34643642 — Surrogate Endpoint (SUR): Blood pressure
Study 33248590 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33248590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33082712 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32955138 — Predictive Biomarker (PRD): Hormone receptor
Study 32955138 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33595905 — Surrogate Endpoint (SUR): Blood pressure
Study 35770578 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32109005 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 33496330 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 33962026 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 33225982 — Surrogate Endpoint (SUR): Serum triglycerides
Study 33225982 — Surrogate Endpoint (SUR): Blood pressure
Study 34174187 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 32444091 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32164507 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 32915796 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32789528 — Surrogate Endpoint (SUR): Blood pressure
Study 34690065 — Surrogate Endpoint (SUR): Blood pressure
Study 36347450 — Predictive Biomarker (PRD): CARM1 mRNA
Genes: CARM1; PRMT4
Study 36347450 — Safety Biomarker (SAF): miR-192
Genes: MIR192
Study 36347450 — Safety Biomarker (SAF): miR-192-5p
Genes: MIR192
Study 35646354 — Surrogate Endpoint (SUR): Blood pressure
Study 33025645 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33338415 — Surrogate Endpoint (SUR): Serum testosterone
Study 32147751 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 32147751 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 32147751 — Predictive Biomarker (PRD): EPAS1 mRNA
Genes: EPAS1; BHLHE73; HIF2A; MOP2; PASD2
Study 34328029 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 35381069 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34485814 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 32587591 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 32587591 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 35493119 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 33567080 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33567080 — Surrogate Endpoint (SUR): Blood pressure
Study 33823506 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 32866619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 32866619 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 32866619 — Predictive Biomarker (PRD): GCLC mRNA
Genes: GCLC; GLCL; GLCLC
Study 32929756 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33356790 — Surrogate Endpoint (SUR): Blood pressure
Study 35130850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35130850 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 35340239 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33539242 — Surrogate Endpoint (SUR): Blood pressure
Study 35796695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35796695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34621327 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 34621327 — Surrogate Endpoint (SUR): Serum creatinine
Study 36076498 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36076498 — Surrogate Endpoint (SUR): Blood pressure
Study 36076498 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37449542 — Predictive Biomarker (PRD): Hormone receptor
Study 34032997 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33032071 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34504990 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34504990 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 34504990 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 34504990 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 34504990 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 34504990 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 34504990 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 34504990 — Predictive Biomarker (PRD): Hormone receptor
Study 35691448 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 36229863 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 36229863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36229863 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 36229863 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 36229863 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 33401223 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 32213141 — Surrogate Endpoint (SUR): Blood pressure
Study 34068848 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 34068848 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 35098466 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 36002048 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 32097932 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 35507141 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 34193503 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34193503 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32875927 — Surrogate Endpoint (SUR): Blood pressure
Study 34313633 — Surrogate Endpoint (SUR): Blood pressure
Study 32293463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34906660 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 34883184 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 34883184 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36341846 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 32529884 — Surrogate Endpoint (SUR): Blood pressure
Study 33613861 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 36008120 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 34115061 — Surrogate Endpoint (SUR): Bone mineral density
Study 35640246 — Surrogate Endpoint (SUR): Pathological complete response
Study 32778788 — Surrogate Endpoint (SUR): Blood pressure
Study 32093785 — Predictive Biomarker (PRD): SP3 mRNA
Genes: SP3
Study 33486403 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 35912731 — Predictive Biomarker (PRD): HPV E2
Study 33589758 — Surrogate Endpoint (SUR): Blood pressure
Study 33259892 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36221338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32749459 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35982162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 34341098 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 34341098 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 34341098 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35554396 — Surrogate Endpoint (SUR): Blood pressure
Study 33415448 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33940126 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 35901049 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 33682983 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 32044205 — Surrogate Endpoint (SUR): Blood pressure
Study 33287715 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 32825020 — Predictive Biomarker (PRD): EVC mRNA
Genes: EVC
Study 35334791 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33166694 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 34531293 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33789010 — Surrogate Endpoint (SUR): Urinary oxalate
Study 33124156 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 33124156 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32946590 — Surrogate Endpoint (SUR): Probing pocket depth
Study 34538125 — Surrogate Endpoint (SUR): Blood pressure
Study 32865597 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 34605319 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 32435011 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35654052 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 35654052 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 35654052 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 36314570 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 36314570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36314570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33130949 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 35767384 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35767384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32247951 — Safety Biomarker (SAF): Reactive oxygen species
Study 32247951 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 33368307 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 36091030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36091030 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34047371 — Surrogate Endpoint (SUR): Blood pressure
Study 32067691 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36100672 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32569024 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 36071284 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 34480060 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 34480060 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35863669 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 35863669 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34459060 — Surrogate Endpoint (SUR): Blood pressure
Study 34068687 — Surrogate Endpoint (SUR): Blood pressure
Study 34269503 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34016024 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35001501 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35001501 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36089810 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 36089810 — Surrogate Endpoint (SUR): Blood pressure
Study 36089810 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33007353 — Surrogate Endpoint (SUR): Serum potassium
Study 34600178 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 36397221 — Monitoring Biomarker (MOI): Procalcitonin
Study 36397221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36397221 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 35341647 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33780274 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 33780274 — Predictive Biomarker (PRD): Hormone receptor
Study 34603765 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 32147925 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36028073 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36028073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36028073 — Safety Biomarker (SAF): BDNF
Study 34307194 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 34307194 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 32797085 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 32797085 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 32797085 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 36112590 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 34075589 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34425071 — Predictive Biomarker (PRD): MAP3K5 mRNA
Genes: MAP3K5; ASK1; MAPKKK5; MEKK5
Study 34425071 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 34425071 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 33419872 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32217148 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 32217148 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study 32217148 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 32217148 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32217148 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36266163 — Surrogate Endpoint (SUR): Blood pressure
Study 33766837 — Surrogate Endpoint (SUR): Blood pressure
Study 32138501 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 32138501 — Surrogate Endpoint (SUR): Blood pressure
Study 33461302 — Surrogate Endpoint (SUR): Blood pressure
Study 35730409 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 33142467 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 33142467 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32123205 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 37045502 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32576229 — Surrogate Endpoint (SUR): Blood pressure
Study 34536258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32156136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32156136 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32156136 — Surrogate Endpoint (SUR): Serum creatinine
Study 33840387 — Predictive Biomarker (PRD): BNC1 mRNA
Genes: BNC1; BNC
Study 35605429 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32472357 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 35172440 — Safety Biomarker (SAF): Hyaluronic acid
Study 35303160 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 34002910 — Monitoring Biomarker (MOI): HBV DNA
Study 35039269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32969605 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33993740 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35059248 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34839601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32584199 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32584199 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32584199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32584199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32584199 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35114798 — Surrogate Endpoint (SUR): Blood pressure
Study 36311525 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35847786 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 33675342 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35436142 — Surrogate Endpoint (SUR): Serum creatinine
Study 32540725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33196921 — Predictive Biomarker (PRD): CD37 mRNA
Genes: CD37; TSPAN26
Study 32512262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35039206 — Predictive Biomarker (PRD): FDPS mRNA
Genes: FDPS; FPS; KIAA1293
Study 33556442 — Surrogate Endpoint (SUR): Blood pressure
Study 33630072 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35176038 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 35176038 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 35728577 — Surrogate Endpoint (SUR): Probing pocket depth
Study 32124801 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 32124801 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 32124801 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 32124801 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 32124801 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32124801 — Predictive Biomarker (PRD): RLN2 mRNA
Genes: RLN2
Study 32199708 — Surrogate Endpoint (SUR): Serum sodium
Study 36243884 — Surrogate Endpoint (SUR): Blood pressure
Study 34635114 — Surrogate Endpoint (SUR): Plasma ammonia
Study 33429977 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 33429977 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 33573042 — Predictive Biomarker (PRD): NRG4 mRNA
Genes: NRG4
Study 33423267 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 33423267 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 32712674 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 32921111 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35874678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35850110 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 32054473 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 34481017 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33757723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2