TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32513290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34562208 — Surrogate Endpoint (SUR): Blood pressure
Study 32461104 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 35648674 — Surrogate Endpoint (SUR): Blood pressure
Study 33553973 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 33587500 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33587500 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34971577 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 34971577 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 32967513 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35263346 — Surrogate Endpoint (SUR): Blood pressure
Study 32217842 — Safety Biomarker (SAF): Hyaluronic acid
Study 35390320 — Surrogate Endpoint (SUR): Blood pressure
Study 34022170 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 32918078 — Surrogate Endpoint (SUR): Blood pressure
Study 32305105 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 35534184 — Surrogate Endpoint (SUR): Blood pressure
Study 34404384 — Surrogate Endpoint (SUR): Blood pressure
Study 36008814 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 36008814 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 35848358 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 35848358 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35524184 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33641272 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 32634046 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 32615575 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35807851 — Surrogate Endpoint (SUR): Blood pressure
Study 32653726 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study 32653726 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 34274366 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 33277698 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35713224 — Surrogate Endpoint (SUR): Probing pocket depth
Study 35509104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33506357 — Surrogate Endpoint (SUR): Serum uric acid
Study 33506357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33140515 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33140515 — Surrogate Endpoint (SUR): Pathological complete response
Study 33504175 — Predictive Biomarker (PRD): PCBD1 mRNA
Genes: PCBD1; DCOH; PCBD
Study 35674733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32715442 — Predictive Biomarker (PRD): UGT2B17 mRNA
Genes: UGT2B17
Study 35143041 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 33748882 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32690830 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33910581 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 33336844 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 34124244 — Surrogate Endpoint (SUR): Serum uric acid
Study 35793047 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 35671902 — Predictive Biomarker (PRD): BAMBI mRNA
Genes: BAMBI; NMA
Study 33218568 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 33727260 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 33727260 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32833549 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32833549 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34261052 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34261052 — Surrogate Endpoint (SUR): Blood pressure
Study 34865586 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 32662661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35356068 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 35356068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35356068 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 35356068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33222584 — Surrogate Endpoint (SUR): Blood pressure
Study 33222584 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34609029 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33681988 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 36190377 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study 36190377 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study 36190377 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 36190377 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 35639174 — Surrogate Endpoint (SUR): Bone mineral density
Study 36592046 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33143432 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 32856190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34057124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36113170 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 36314686 — Surrogate Endpoint (SUR): Blood pressure
Study 36421345 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 32507446 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 32507446 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 34534510 — Surrogate Endpoint (SUR): Blood pressure
Study 33145753 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 34952708 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 32536118 — Surrogate Endpoint (SUR): Blood pressure
Study 34980598 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34980598 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 34980598 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34477818 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35640729 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35640729 — Surrogate Endpoint (SUR): Blood pressure
Study 32586079 — Surrogate Endpoint (SUR): Bone mineral density
Study 35924272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32957336 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32529753 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 35291408 — Surrogate Endpoint (SUR): Blood pressure
Study 34380790 — Predictive Biomarker (PRD): CFL1 mRNA
Genes: CFL1; CFL
Study 33164580 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33074857 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33074857 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 33074857 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 36270493 — Predictive Biomarker (PRD): THEMIS mRNA
Genes: THEMIS; C6orf190; C6orf207
Study 33962511 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32376946 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 35273943 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 36307353 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36307353 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35941622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33284965 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 33284965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32562884 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 33026449 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 35339715 — Monitoring Biomarker (MOI): Procalcitonin
Study 35339715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36356632 — Surrogate Endpoint (SUR): Blood pressure
Study 34881696 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 32894809 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36367721 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 36145083 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35857296 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35063278 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 34540784 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 33358124 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34338408 — Surrogate Endpoint (SUR): Blood pressure
Study 34544526 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 32150750 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32150750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32150750 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 33895882 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 33895882 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32682697 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 34615719 — Predictive Biomarker (PRD): CSF1 mRNA
Genes: CSF1
Study 33181655 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 35553967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35553967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35553967 — Surrogate Endpoint (SUR): Bone mineral density
Study 33421840 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 33421840 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32963294 — Surrogate Endpoint (SUR): Blood pressure
Study 35896533 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 35896533 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 35896533 — Safety Biomarker (SAF): BDNF
Study 35147131 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35300759 — Surrogate Endpoint (SUR): Blood pressure
Study 33197657 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 33197657 — Safety Biomarker (SAF): Reactive oxygen species
Study 35723120 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 36482599 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 36482599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36482599 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33081570 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33081570 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 37932788 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 32492920 — Predictive Biomarker (PRD): DEGS1 mRNA
Genes: DEGS1; DES1; MLD; MIG15
Study 32456097 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33031557 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 33031557 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33031557 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 33031557 — Predictive Biomarker (PRD): PLIN5 mRNA
Genes: PLIN5; LSDP5; OXPAT; PAT-1
Study 32685097 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 34006923 — Surrogate Endpoint (SUR): Blood pressure
Study 37199879 — Surrogate Endpoint (SUR): Blood pressure
Study 32305995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33002672 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33002672 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32304519 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 35603652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35603652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35603652 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 35603652 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 35603652 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32740293 — Surrogate Endpoint (SUR): Blood pressure
Study 32227774 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32701012 — Safety Biomarker (SAF): Hyaluronic acid
Study 35218726 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36268677 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 36268677 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 94240848 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 36222207 — Surrogate Endpoint (SUR): Blood pressure
Study 36222207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32709656 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 35491578 — Surrogate Endpoint (SUR): Bone mineral density
Study 35925834 — Safety Biomarker (SAF): Hyaluronic acid
Study 34190995 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34190995 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34190995 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 33596508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32319999 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32718927 — Surrogate Endpoint (SUR): Blood pressure
Study 34536355 — Surrogate Endpoint (SUR): Blood pressure
Study 34151132 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34151132 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 34156898 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34978535 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 32844703 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 33985681 — Predictive Biomarker (PRD): THEMIS mRNA
Genes: THEMIS; C6orf190; C6orf207
Study 33651448 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 32355123 — Monitoring Biomarker (MOI): HBV DNA
Study 32355123 — Surrogate Endpoint (SUR): Bone mineral density
Study 34750553 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 33373806 — Surrogate Endpoint (SUR): Bone mineral density
Study 34315495 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35085742 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 34799582 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34799582 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 36185291 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36185291 — Safety Biomarker (SAF): BDNF
Study 34956580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33772885 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34595983 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study 33008106 — Surrogate Endpoint (SUR): Blood pressure
Study 33503851 — Predictive Biomarker (PRD): 14-3-3 protein sigma
Genes: SFN; HME1
Study 33008934 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34983646 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 33233227 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 34534883 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 34534883 — Surrogate Endpoint (SUR): Serum uric acid
Study 34534883 — Surrogate Endpoint (SUR): Serum creatinine
Study 34534883 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 34706556 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34706556 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33683939 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 34711976 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 34711976 — Surrogate Endpoint (SUR): Blood pressure
Study 33757646 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 33757646 — Surrogate Endpoint (SUR): Blood pressure
Study 36339420 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 32374623 — Predictive Biomarker (PRD): NUCB1 mRNA
Genes: NUCB1; NUC
Study 33417321 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study 33417321 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 33417321 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32316391 — Surrogate Endpoint (SUR): Serum uric acid
Study 33894335 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32829109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32829109 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32829109 — Safety Biomarker (SAF): IL-6 and IL-10
Study 35338469 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 35338469 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 35718502 — Surrogate Endpoint (SUR): Serum creatinine
Study 35853998 — Surrogate Endpoint (SUR): Serum creatinine
Study 32772491 — Surrogate Endpoint (SUR): Blood pressure
Study 35871497 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34605026 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34605026 — Safety Biomarker (SAF): BDNF
Study 35551683 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 33431374 — Predictive Biomarker (PRD): DISC1 mRNA
Genes: DISC1; KIAA0457
Study 33431374 — Predictive Biomarker (PRD): GBX2 mRNA
Genes: GBX2
Study 33431374 — Predictive Biomarker (PRD): HERC2 mRNA
Genes: HERC2
Study 34538090 — Surrogate Endpoint (SUR): Blood pressure
Study 35102171 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 33908636 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 32367748 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32367748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33165125 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 32844885 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36231316 — Surrogate Endpoint (SUR): Blood pressure
Study 33951415 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 33951415 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34378087 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33759069 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study 34059080 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 34059080 — Safety Biomarker (SAF): Hyaluronic acid
Study 32446306 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32446306 — Safety Biomarker (SAF): Urinary microalbumin
Study 32446306 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33147541 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 33147541 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 33374554 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32739320 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33716004 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 33716004 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 32584415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32466879 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32466879 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 33063528 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33063528 — Safety Biomarker (SAF): BDNF
Study 35488479 — Surrogate Endpoint (SUR): Bone mineral density
Study 33607008 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 35867285 — Surrogate Endpoint (SUR): Probing pocket depth
Study 36136236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36136236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34761730 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1