TrialPanorama/TrialPanorama-database huggingface dataset:
Study 34737220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34737220 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 34737220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34737220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36030971 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 33269836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33269836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33539944 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 33539944 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32238947 — Surrogate Endpoint (SUR): Blood pressure
Study 35089384 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 35089384 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 35089384 — Surrogate Endpoint (SUR): Blood pressure
Study 35438829 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 33605981 — Surrogate Endpoint (SUR): Blood pressure
Study 35871120 — Surrogate Endpoint (SUR): Blood pressure
Study 35871120 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 34670954 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study 33394979 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 35380689 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 32285590 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 35057457 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 35057457 — Surrogate Endpoint (SUR): Bone mineral density
Study 34959951 — Surrogate Endpoint (SUR): Blood pressure
Study 35030036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 35030036 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 32203933 — Surrogate Endpoint (SUR): Blood pressure
Study 34217854 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 34217854 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 34853156 — Surrogate Endpoint (SUR): Blood pressure
Study 33485635 — Surrogate Endpoint (SUR): Blood pressure
Study 33485635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33485635 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34131267 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 34131267 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34591808 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 34111277 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 33280041 — Surrogate Endpoint (SUR): Bone mineral density
Study 32627474 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32871952 — Safety Biomarker (SAF): GAT1
Genes: SLC6A1; GABATR; GABATHG; GAT-1; hGAT-1
Study 32871952 — Predictive Biomarker (PRD): SYT1 mRNA
Genes: SYT1; SVP65; SYT
Study 32871952 — Predictive Biomarker (PRD): COL19A1 mRNA
Genes: COL19A1
Study 32871952 — Predictive Biomarker (PRD): RIMS2 mRNA
Genes: RIMS2; KIAA0751; RAB3IP3; RIM2
Study 32871952 — Predictive Biomarker (PRD): COL1A2 mRNA
Genes: COL1A2
Study 33589582 — Surrogate Endpoint (SUR): Blood pressure
Study 34914243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34914243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33417292 — Surrogate Endpoint (SUR): Blood pressure
Study 33405474 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32633217 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 34489928 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36107991 — Surrogate Endpoint (SUR): Blood pressure
Study 35129111 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32883514 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 34530759 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 34530759 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study 34530759 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 34530759 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 33651633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33904792 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 32909675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32909675 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 36081429 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32712034 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 33727257 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 32267058 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32750212 — Predictive Biomarker (PRD): PPP3R1 mRNA
Genes: PPP3R1; CNA2; CNB
Study 34407884 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34407884 — Surrogate Endpoint (SUR): Blood pressure
Study 32242215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32242215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32242215 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32242215 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 36152639 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 34165503 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34165503 — Predictive Biomarker (PRD): Hormone receptor
Study 35128627 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 34472736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32089359 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34694401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34694401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36460919 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 32993775 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 34112180 — Surrogate Endpoint (SUR): Pathological complete response
Study 34413169 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 34413169 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 34413169 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35762124 — Surrogate Endpoint (SUR): Bone mineral density
Study 32711800 — Surrogate Endpoint (SUR): Bone mineral density
Study 35181698 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DMRT1 mRNA
Genes: DMRT1; DMT1
Study 35677967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35677967 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34435513 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 34928960 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36354040 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 35579350 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 32730985 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35860804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35860804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35860804 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35143622 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 33788452 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33788452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33788452 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36164012 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 36164012 — Predictive Biomarker (PRD): ACVR1 mRNA
Genes: ACVR1; ACVRLK2
Study 32931612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32931612 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32931612 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32800029 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 35615783 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34431258 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 36476455 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33385521 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33385521 — Predictive Biomarker (PRD): Hormone receptor
Study 35200145 — Surrogate Endpoint (SUR): Blood pressure
Study 616461890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34767068 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 35665728 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33248570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36029969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34379915 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32921196 — Surrogate Endpoint (SUR): Blood pressure
Study 35405955 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35880650 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 33729323 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33729323 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33729323 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 33161472 — Safety Biomarker (SAF): Reactive oxygen species
Study 32452208 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 33153350 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34132789 — Surrogate Endpoint (SUR): Bone mineral density
Study 36164983 — Surrogate Endpoint (SUR): Blood pressure
Study 35121216 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 32851660 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34515977 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 35008009 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 33007981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33007981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32883309 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 34755655 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 32109257 — Surrogate Endpoint (SUR): Blood pressure
Study 32505171 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 32115970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32115970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33730455 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 33730455 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 33730455 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35732749 — Safety Biomarker (SAF): Reactive oxygen species
Study 34072630 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 34072630 — Safety Biomarker (SAF): Reactive oxygen species
Study 35579077 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 35901367 — Predictive Biomarker (PRD): OTP mRNA
Genes: OTP
Study 32864754 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33380585 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33323886 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 34264305 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34264305 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 33294980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33814236 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33814236 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32130025 — Surrogate Endpoint (SUR): Blood pressure
Study 36282078 — Safety Biomarker (SAF): Interleukin 1
Study 35300246 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32648662 — Surrogate Endpoint (SUR): Serum creatinine
Study 32586736 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 32016654 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36173064 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36173064 — Safety Biomarker (SAF): BDNF
Study 35664433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35664433 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33004704 — Surrogate Endpoint (SUR): Blood pressure
Study 34233722 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 36332179 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 36332179 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 35627588 — Surrogate Endpoint (SUR): Bacterial count
Study 32027349 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33970403 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33676417 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 33676417 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 36058695 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36058695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36058695 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 32725293 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 32585668 — Surrogate Endpoint (SUR): Blood pressure
Study 36445398 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36445398 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 36445398 — Surrogate Endpoint (SUR): Blood pressure
Study 32830462 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32780844 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 33789963 — Surrogate Endpoint (SUR): Bone mineral density
Study 32869399 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 34182806 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 34182806 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32718724 — Surrogate Endpoint (SUR): Blood pressure
Study 33625468 — Surrogate Endpoint (SUR): Blood pressure
Study 32840598 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 35427357 — Surrogate Endpoint (SUR): Blood pressure
Study 35427357 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35654467 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 33875738 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 35202418 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 35202418 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32086657 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 35871234 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 36163263 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 32966573 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34265047 — Predictive Biomarker (PRD): ROCK2 mRNA
Genes: ROCK2; KIAA0619
Study 34265047 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 34265047 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 37312098 — Surrogate Endpoint (SUR): Blood pressure
Study 32092047 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 33610731 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 33610731 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 33199421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35544283 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 34561419 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 34561419 — Predictive Biomarker (PRD): NRM mRNA
Genes: NRM; NRM29; UNQ555/PRO1112
Study 33887147 — Surrogate Endpoint (SUR): Serum calcium
Study 35444642 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 35444642 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 35444642 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 34453262 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 36178534 — Safety Biomarker (SAF): Reactive oxygen species
Study 34496170 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34496170 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33181328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33181328 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33181328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34460815 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 35357079 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 33378609 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33692093 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 32784192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33917889 — Predictive Biomarker (PRD): EVC mRNA
Genes: EVC
Study 36388277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32658250 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33989330 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 32961589 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 32679761 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 35262910 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 35262910 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 32771461 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34320285 — Predictive Biomarker (PRD): Hormone receptor
Study 34484560 — Predictive Biomarker (PRD): ATF4 mRNA
Genes: ATF4; CREB2; TXREB
Study 32580579 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 33296467 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 32407947 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 35710253 — Surrogate Endpoint (SUR): Blood pressure
Study 35710253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35710253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 37698371 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 33459908 — Predictive Biomarker (PRD): THSD7A mRNA
Genes: THSD7A; KIAA0960
Study 35400993 — Surrogate Endpoint (SUR): Blood pressure
Study 36189824 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33516195 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 32085626 — Surrogate Endpoint (SUR): Blood pressure
Study 32365090 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 34154926 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34154926 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35372979 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 33462955 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 33462955 — Surrogate Endpoint (SUR): Serum triglycerides
Study 33462955 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35974290 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 35974290 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33639516 — Surrogate Endpoint (SUR): Blood pressure