TrialPanorama/TrialPanorama-database huggingface dataset:
Study 34269262 — Safety Biomarker (SAF): Reactive oxygen species
Study 35926901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33015813 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32347765 — Predictive Biomarker (PRD): RARB mRNA
Genes: RARB; HAP; NR1B2
Study 34092026 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 36229537 — Surrogate Endpoint (SUR): Blood pressure
Study 32250250 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 33346518 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32709430 — Surrogate Endpoint (SUR): Forced vital capacity
Study 36164102 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 36164102 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 33393645 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35257498 — Surrogate Endpoint (SUR): Blood pressure
Study 33287744 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 32889771 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 36411058 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35590386 — Predictive Biomarker (PRD): TWIST1 mRNA
Genes: TWIST1; BHLHA38; TWIST
Study 36156571 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 91213894 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34954348 — Surrogate Endpoint (SUR): Blood pressure
Study 32760144 — Surrogate Endpoint (SUR): Blood pressure
Study 35810012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35810012 — Surrogate Endpoint (SUR): Probing pocket depth
Study 35247906 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 35247906 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 32529630 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32529630 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 35459114 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35459114 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 33875487 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 36091017 — Predictive Biomarker (PRD): IRAK1 mRNA
Genes: IRAK1; IRAK
Study 36091017 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 36091017 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PLXNB3 mRNA
Genes: PLXNB3; KIAA1206; PLXN6
Study 32927609 — Surrogate Endpoint (SUR): Blood pressure
Study 34541941 — Surrogate Endpoint (SUR): Serum sodium
Study 34541941 — Surrogate Endpoint (SUR): Blood pressure
Study 36193978 — Predictive Biomarker (PRD): TFEB mRNA
Genes: TFEB; BHLHE35
Study 32835882 — Surrogate Endpoint (SUR): Probing pocket depth
Study 33801339 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 33801339 — Predictive Biomarker (PRD): SEC16B mRNA
Genes: SEC16B; KIAA1928; LZTR2; RGPR; SEC16S
Study 33801339 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33801339 — Safety Biomarker (SAF): BDNF
Study 32333010 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32213473 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33616265 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32297383 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 34210411 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34534317 — Surrogate Endpoint (SUR): Serum testosterone
Study 34537827 — Surrogate Endpoint (SUR): Blood pressure
Study 33267641 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 34491388 — Surrogate Endpoint (SUR): Serum uric acid
Study 34196161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34196161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34196161 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 34176716 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 34036692 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34036692 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 35395638 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 34762211 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34762211 — Safety Biomarker (SAF): BDNF
Study 33788454 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 34491645 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34491645 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34491645 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34491645 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34177615 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 35121204 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35065898 — Surrogate Endpoint (SUR): Blood pressure
Study 33517855 — Surrogate Endpoint (SUR): Blood pressure
Study 36411989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32998416 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32998416 — Surrogate Endpoint (SUR): Blood pressure
Study 32998416 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34214153 — Surrogate Endpoint (SUR): Serum creatinine
Study 34214153 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 36169160 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 32059704 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 32059704 — Predictive Biomarker (PRD): CALML6 mRNA
Genes: CALML6; CAGLP; CALGP
Study 32059704 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 34739947 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 35056349 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 35413570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35413570 — Surrogate Endpoint (SUR): Blood pressure
Study 32008289 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33290900 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study 33290900 — Predictive Biomarker (PRD): PASD1 mRNA
Genes: PASD1
Study 33290900 — Predictive Biomarker (PRD): SPANXA1 mRNA
Genes: SPANXA1; SPANXA; SPANXA2
Study 33290900 — Predictive Biomarker (PRD): GAGE1 mRNA
Genes: GAGE1
Study 32215577 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 34921022 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34921022 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 33513820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34923514 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 36474739 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34740705 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study 34620621 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 34620621 — Surrogate Endpoint (SUR): Blood pressure
Study 32784372 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 35419064 — Surrogate Endpoint (SUR): Blood pressure
Study 35419064 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33029934 — Surrogate Endpoint (SUR): Blood pressure
Study 32028385 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36028881 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33314313 — Surrogate Endpoint (SUR): Bone mineral density
Study 34814113 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34773094 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 35720883 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33293172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33293172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34369680 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 34369680 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 34369680 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34369680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34369680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34369680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32909356 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33438008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35021269 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 35021269 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 32123978 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 32769914 — Predictive Biomarker (PRD): NUBP1 mRNA
Genes: NUBP1; NBP; NBP1
Study 33025678 — Predictive Biomarker (PRD): BTG2 mRNA
Genes: BTG2; PC3
Study 35303068 — Surrogate Endpoint (SUR): Pathological complete response
Study 32558287 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 33290108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35131978 — Safety Biomarker (SAF): Coagulation factor Va
Genes: F5
Study 33346899 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33370736 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 33370736 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 34917038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35999630 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35999630 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 35999630 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 35999630 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33938071 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 32895353 — Safety Biomarker (SAF): Hyaluronic acid
Study 36136263 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 32398433 — Surrogate Endpoint (SUR): Blood pressure
Study 32564557 — Monitoring Biomarker (MOI): HBV DNA
Study 34453620 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 32104687 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32104687 — Surrogate Endpoint (SUR): Serum triglycerides
Study 32104687 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33051038 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33879015 — Surrogate Endpoint (SUR): Serum sodium
Study 32788396 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 32134754 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32618258 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 34550903 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 34550903 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34529114 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 32135337 — Surrogate Endpoint (SUR): Blood pressure
Study 35063205 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 32722957 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34851734 — Surrogate Endpoint (SUR): Blood pressure
Study 32197936 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32282882 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34028126 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34790253 — Surrogate Endpoint (SUR): Bone mineral density
Study 32709500 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32331058 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35168581 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 34134131 — Surrogate Endpoint (SUR): Blood pressure
Study 32118713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32118713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32118713 — Monitoring Biomarker (MOI): Procalcitonin
Study 32118713 — Safety Biomarker (SAF): IL-6 and IL-10
Study 32118713 — Surrogate Endpoint (SUR): Serum creatinine
Study 33977745 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35315603 — Monitoring Biomarker (MOI): HBV DNA
Study 35085018 — Surrogate Endpoint (SUR): Blood pressure
Study 35761123 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 34193504 — Predictive Biomarker (PRD): PSEN1 mRNA
Genes: PSEN1; AD3; PS1; PSNL1
Study 35764992 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35764992 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32687695 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 32701903 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35933563 — Surrogate Endpoint (SUR): Bone mineral density
Study 34521624 — Predictive Biomarker (PRD): Hormone receptor
Study 34419680 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32828825 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 32828825 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33546045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35334923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32501868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32501868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32501868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32501868 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 32546198 — Predictive Biomarker (PRD): Hormone receptor
Study 33858855 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33858855 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 33181508 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33181508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33181508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34389273 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 34389273 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 33040565 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 35789270 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 35789270 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34090625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34090625 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 33070223 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 34118388 — Surrogate Endpoint (SUR): Blood pressure
Study 34707496 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35373729 — Predictive Biomarker (PRD): MYB mRNA
Genes: MYB
Study 35373729 — Predictive Biomarker (PRD): HNF1A mRNA
Genes: HNF1A; TCF1
Study 35373729 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 33847634 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 34650034 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34650034 — Predictive Biomarker (PRD): DSPP mRNA
Genes: DSPP
Study 34650034 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 34650034 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 33569770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34257640 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 35332062 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32917529 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 34162831 — Monitoring Biomarker (MOI): HBV DNA
Study 33301018 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35018575 — Predictive Biomarker (PRD): MYF6 mRNA
Genes: MYF6; BHLHC4; MRF4
Study 35018575 — Predictive Biomarker (PRD): DCN mRNA
Genes: DCN; SLRR1B
Study 34737064 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 34737064 — Predictive Biomarker (PRD): FGF18 mRNA
Genes: FGF18; UNQ420/PRO856
Study 33281083 — Safety Biomarker (SAF): Hyaluronic acid
Study 34526921 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 32548915 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 35944747 — Surrogate Endpoint (SUR): Blood pressure
Study 32701140 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32701140 — Predictive Biomarker (PRD): Hormone receptor
Study 36282530 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 32673171 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 36236307 — Surrogate Endpoint (SUR): Blood pressure
Study 34939397 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 32988827 — Predictive Biomarker (PRD): NKRF mRNA
Genes: NKRF; ITBA4; NRF
Study 35131452 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35131452 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35131452 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 36191176 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 32285723 — Predictive Biomarker (PRD): EIF2AK2 mRNA
Genes: EIF2AK2; PKR; PRKR
Study 33347677 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 33744617 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34049911 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 33151266 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33151266 — Predictive Biomarker (PRD): Hormone receptor
Study 34788571 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 34788571 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34204400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34204400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32820334 — Surrogate Endpoint (SUR): Blood pressure
Study 32820334 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32202637 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 35719236 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34023797 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 34563096 — Safety Biomarker (SAF): Nucleotide triphosphate diphosphatase NUDT15
Genes: NUDT15; MTH2
Study 34563096 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 34530254 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 34460948 — Safety Biomarker (SAF): Th2 cell
Study 34370656 — Surrogate Endpoint (SUR): Bone mineral density
Study 34537124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35590284 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32917784 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 32917784 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 34923559 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32184305 — Predictive Biomarker (PRD): WEE1 mRNA
Genes: WEE1
Study 33955686 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 33955686 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 33955686 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 32438192 — Surrogate Endpoint (SUR): Blood pressure
Study 32438192 — Safety Biomarker (SAF): miR-30a-5p
Genes: MIR30A
Study 33812492 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 33172883 — Predictive Biomarker (PRD): CALR mRNA
Genes: CALR; CRTC
Study 33172883 — Predictive Biomarker (PRD): Phospholipase A2 inhibitory protein
Genes: ANXA1; ANX1; LPC1
Study 33172883 — Predictive Biomarker (PRD): LRP1 mRNA
Genes: LRP1; A2MR; APR
Study 32319313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35250032 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 34496669 — Surrogate Endpoint (SUR): Blood pressure