TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33826132 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study 34933097 — Surrogate Endpoint (SUR): Blood pressure
Study 32419128 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35607776 — Pharmacodynamic Biomarker (PDY): Ataxin-2
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 35395021 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35395021 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 35750555 — Predictive Biomarker (PRD): SREBF1 mRNA
Genes: SREBF1; BHLHD1; SREBP1
Study 35750555 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 35927518 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 35927518 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 36410666 — Surrogate Endpoint (SUR): Bone mineral density
Study 33879849 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 33879849 — Surrogate Endpoint (SUR): Blood pressure
Study 33090462 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33090462 — Safety Biomarker (SAF): Reactive oxygen species
Study 32404535 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32533012 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 36362620 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 33710466 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study 33842996 — Surrogate Endpoint (SUR): Probing pocket depth
Study 34006553 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 32272513 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 34131999 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 34486701 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 35706490 — Safety Biomarker (SAF): Reactive oxygen species
Study 35706490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33049929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 32049627 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34969033 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34836393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34836393 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 32109317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32109317 — Surrogate Endpoint (SUR): Probing pocket depth
Study 35140794 — Surrogate Endpoint (SUR): Blood pressure
Study 35140794 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36045651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34779576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33472997 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33628012 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32186976 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 36608969 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 33503173 — Predictive Biomarker (PRD): WNK1 mRNA
Genes: WNK1; HSN2; KDP; KIAA0344; PRKWNK1
Study 34563169 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 34563169 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 34563169 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 35329066 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 35329066 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35329066 — Surrogate Endpoint (SUR): Blood pressure
Study 35329066 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 33895220 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32515156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32515156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33383447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34560806 — Surrogate Endpoint (SUR): Blood pressure
Study 32202075 — Surrogate Endpoint (SUR): Blood pressure
Study 33454216 — Monitoring Biomarker (MOI): Procalcitonin
Study 35879728 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 34684536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32844712 — Surrogate Endpoint (SUR): Serum testosterone
Study 32348539 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 34741460 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33792800 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34655432 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32798835 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 33275766 — Predictive Biomarker (PRD): IRAK1 mRNA
Genes: IRAK1; IRAK
Study 36129240 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 34215703 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 32376544 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 32376544 — Surrogate Endpoint (SUR): Serum creatinine
Study 32376544 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 32376544 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32159530 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 34786695 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32909365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32909365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32909365 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32909365 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32909365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32641142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32641142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32056985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32056985 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32483770 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 32483770 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 32450915 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34993571 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32843527 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 32843527 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32843527 — Predictive Biomarker (PRD): CD8A mRNA
Genes: CD8A; MAL
Study 32843527 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32843527 — Predictive Biomarker (PRD): PDCD1 mRNA
Genes: PDCD1; PD1
Study 32843527 — Predictive Biomarker (PRD): MYBL2 mRNA
Genes: MYBL2; BMYB
Study 616854037 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 34077237 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32546278 — Predictive Biomarker (PRD): ROCK1 mRNA
Genes: ROCK1
Study 32546278 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 32546278 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 32546278 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34645251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32957420 — Surrogate Endpoint (SUR): Bone mineral density
Study 35969032 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 32404378 — Surrogate Endpoint (SUR): Blood pressure
Study 32404378 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32871554 — Surrogate Endpoint (SUR): Blood pressure
Study 34863994 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 34863994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32164888 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35384254 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 36114009 — Predictive Biomarker (PRD): TCF3 mRNA
Genes: TCF3; BHLHB21; E2A; ITF1
Study 36114009 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 34329984 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 34329984 — Predictive Biomarker (PRD): OCLN mRNA
Genes: OCLN
Study 34329984 — Predictive Biomarker (PRD): CLDN1 mRNA
Genes: CLDN1; CLD1; SEMP1; UNQ481/PRO944
Study 34329984 — Predictive Biomarker (PRD): CLDN4 mRNA
Genes: CLDN4; CPER; CPETR1; WBSCR8
Study 34329984 — Safety Biomarker (SAF): Interleukin 1
Study 34329984 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 35373026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35373026 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 35294298 — Surrogate Endpoint (SUR): Blood pressure
Study 36272026 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 36272026 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33355200 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 32816002 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32816002 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35148329 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 33559354 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 33706870 — Surrogate Endpoint (SUR): Blood pressure
Study 32151822 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34289428 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 34289428 — Predictive Biomarker (PRD): TBK1 mRNA
Genes: TBK1; NAK
Study 36006772 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 35063267 — Surrogate Endpoint (SUR): Blood pressure
Study 35969194 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 35969194 — Surrogate Endpoint (SUR): Blood pressure
Study 34451039 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 32293798 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 32147078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32147078 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 32147078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33772502 — Surrogate Endpoint (SUR): Blood pressure
Study 35246585 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35246585 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32701512 — Predictive Biomarker (PRD): CSMD1 mRNA
Genes: CSMD1; KIAA1890; UNQ5952/PRO19863
Study 32701512 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 32701512 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35963411 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 33483840 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34001096 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 34444711 — Surrogate Endpoint (SUR): Blood pressure
Study 34444711 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34444711 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34424907 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 32316918 — Surrogate Endpoint (SUR): Blood pressure
Study 34529073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36029496 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 33276383 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study 33276383 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 33276383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33914991 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 33914991 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33914991 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33914991 — Predictive Biomarker (PRD): Hormone receptor
Study 33167994 — Surrogate Endpoint (SUR): Bone mineral density
Study 34357857 — Monitoring Biomarker (MOI): Procalcitonin
Study 34357857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34357857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34357857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34530161 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 33891473 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 35986403 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 34155773 — Surrogate Endpoint (SUR): Blood pressure
Study 34155773 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33307847 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33307847 — Surrogate Endpoint (SUR): Blood pressure
Study 33771945 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36892754 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 34900203 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34900203 — Safety Biomarker (SAF): BDNF
Study 35266219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35266219 — Surrogate Endpoint (SUR): Blood pressure
Study 35266219 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33150355 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 33150355 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 33624705 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33624705 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 33624705 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 33624705 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33624705 — Safety Biomarker (SAF): Reactive oxygen species
Study 35057591 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35057591 — Surrogate Endpoint (SUR): Blood pressure
Study 33422704 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33422704 — Surrogate Endpoint (SUR): Blood pressure
Study 35260354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33262189 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36178574 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 34714130 — Surrogate Endpoint (SUR): Bone mineral density
Study 33584665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33584665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33308469 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35667713 — Surrogate Endpoint (SUR): Blood pressure
Study 32991033 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35655728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34260265 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36094625 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33796948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32243865 — Surrogate Endpoint (SUR): Blood pressure
Study 32210538 — Safety Biomarker (SAF): Hyaluronic acid
Study 35745123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35745123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35745123 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32534040 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32534040 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33569986 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 33076983 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 97426120 — Monitoring Biomarker (MOI): HBV DNA
Study 35709811 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 33166307 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 33166307 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 34491016 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 35538296 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 35538296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35538296 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 32543020 — Surrogate Endpoint (SUR): Serum sodium
Study 32543020 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 32543020 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 36171101 — Surrogate Endpoint (SUR): Blood pressure
Study 34146033 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 33067129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34700294 — Surrogate Endpoint (SUR): Blood pressure
Study 35692074 — Predictive Biomarker (PRD): SLC4A7 mRNA
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 33118432 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 32274653 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 35199237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35199237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34915981 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34787005 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 34125899 — Surrogate Endpoint (SUR): Bone mineral density
Study 34125899 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 35751898 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35751898 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 32026829 — Surrogate Endpoint (SUR): Blood pressure
Study 34859788 — Surrogate Endpoint (SUR): Blood pressure
Study 34859788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34859788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36247849 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 36190380 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 36304748 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33407146 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 36370991 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 33187850 — Safety Biomarker (SAF): Reactive oxygen species
Study 33187850 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35318844 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 34341325 — Surrogate Endpoint (SUR): Blood pressure
Study 34341325 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 34341325 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33626028 — Surrogate Endpoint (SUR): Blood pressure
Study 34959931 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 33450071 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 33450071 — Surrogate Endpoint (SUR): Bone mineral density