TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35430494 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 32397113 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 32397113 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 32397113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): WNT3A mRNA
Genes: WNT3A
Study 32397113 — Predictive Biomarker (PRD): Induced myeloid leukemia cell differentiation protein Mcl-1
Genes: MCL1; BCL2L3
Study 34881510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32916063 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36506062 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 36163945 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 36163945 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32223446 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 32223446 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35966733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35966733 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 35401060 — Surrogate Endpoint (SUR): Blood pressure
Study 35785965 — Surrogate Endpoint (SUR): Blood pressure
Study 33243443 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 34103439 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33407801 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32583957 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34063455 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 34220825 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 34023405 — Predictive Biomarker (PRD): HHIP mRNA
Genes: HHIP; HIP; UNQ5825/PRO19644
Study 35791295 — Surrogate Endpoint (SUR): Serum testosterone
Study 33038531 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 33170536 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 34587941 — Surrogate Endpoint (SUR): Probing pocket depth
Study 36223105 — Surrogate Endpoint (SUR): Blood pressure
Study 35710560 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 35710560 — Predictive Biomarker (PRD): SLC34A3 mRNA
Genes: SLC34A3; NPT2C; NPTIIC
Study 34526950 — Surrogate Endpoint (SUR): Blood pressure
Study 33544719 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 33544719 — Surrogate Endpoint (SUR): Blood pressure
Study 33544719 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33544719 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32492734 — Surrogate Endpoint (SUR): Blood pressure
Study 33025690 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 34256550 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34256550 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32057907 — Predictive Biomarker (PRD): USP2 mRNA
Genes: USP2; UBP41
Study 34618687 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 34618687 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 34618687 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32097286 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 35616304 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34688915 — Predictive Biomarker (PRD): CES2 mRNA
Genes: CES2; ICE
Study 34688915 — Predictive Biomarker (PRD): TRIT1 mRNA
Genes: TRIT1; IPT; MOD5
Study 34781656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34114138 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32853281 — Surrogate Endpoint (SUR): Blood pressure
Study 32346959 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 35092347 — Predictive Biomarker (PRD): Liver iron
Study 34919248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34103538 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34103538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34103538 — Predictive Biomarker (PRD): Hormone receptor
Study 36378660 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35705139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 35705139 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35870380 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 34806261 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 34763309 — Surrogate Endpoint (SUR): Blood pressure
Study 34763309 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36508996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36508996 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 36508996 — Safety Biomarker (SAF): Platelet to lymphocyte
Study 36508996 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33507248 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 34476450 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34476450 — Surrogate Endpoint (SUR): Blood pressure
Study 33711095 — Surrogate Endpoint (SUR): Blood pressure
Study 32376702 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 32376702 — Safety Biomarker (SAF): HLA-DQA1
Genes: CELIAC1
Study 33531453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35942813 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 35942813 — Surrogate Endpoint (SUR): Serum calcium
Study 34819261 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 35933224 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 35105177 — Surrogate Endpoint (SUR): Blood pressure
Study 32023606 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 32023606 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 32023606 — Surrogate Endpoint (SUR): Blood pressure
Study 33731305 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 32438787 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 32717294 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 32717294 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 33099898 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35729493 — Surrogate Endpoint (SUR): Blood pressure
Study 35273107 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 33038066 — Surrogate Endpoint (SUR): Blood pressure
Study 35502340 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 35840747 — Predictive Biomarker (PRD): NRM mRNA
Genes: NRM; NRM29; UNQ555/PRO1112
Study 32107343 — Surrogate Endpoint (SUR): Blood pressure
Study 35906662 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33155236 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 36060969 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 36060969 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 34134812 — Surrogate Endpoint (SUR): Blood pressure
Study 34472693 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32700461 — Predictive Biomarker (PRD): Anti-acetylcholine receptor antibody
Study 32369191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32369191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32533792 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 32533792 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 32533792 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 35768774 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36282988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34545949 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 34545949 — Surrogate Endpoint (SUR): Serum uric acid
Study 32369571 — Surrogate Endpoint (SUR): Probing pocket depth
Study 36207891 — Surrogate Endpoint (SUR): Blood pressure
Study 33536253 — Surrogate Endpoint (SUR): Serum testosterone
Study 33485162 — Surrogate Endpoint (SUR): Blood pressure
Study 35643956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33881472 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 34347775 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35366393 — Predictive Biomarker (PRD): PRKRA mRNA
Genes: PRKRA; PACT; RAX; HSD-14; HSD14
Study 33720069 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35149701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32090389 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 33887343 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34302324 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 34302324 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36306479 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33507592 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33507592 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33749762 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36307161 — Surrogate Endpoint (SUR): Blood pressure
Study 33755227 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33755227 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 34000119 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 33248586 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 36325128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36325128 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32959588 — Surrogate Endpoint (SUR): Bone mineral density
Study 35461434 — Surrogate Endpoint (SUR): Blood pressure
Study 35791582 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 35791582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35791582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35791582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33047116 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 33249003 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 32878963 — Predictive Biomarker (PRD): ANTXR1 mRNA
Genes: ANTXR1; ATR; TEM8
Study 33035599 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 34757657 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 36206054 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 36206054 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32826409 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32574722 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HSD3B1 mRNA
Genes: HSD3B1; 3BH; HSDB3A
Study 34758731 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 34758731 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 34942136 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 37365436 — Predictive Biomarker (PRD): Hormone receptor
Study 37365436 — Surrogate Endpoint (SUR): Bone mineral density
Study 32824394 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 32824394 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 37164603 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 32667286 — Predictive Biomarker (PRD): TLR8 mRNA
Genes: TLR8; UNQ249/PRO286
Study 35380672 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 32275365 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 32222857 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35645167 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 33586796 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 32086272 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35921122 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 36353918 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 33990958 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 36548296 — Surrogate Endpoint (SUR): Blood pressure
Study 33485960 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35582947 — Surrogate Endpoint (SUR): Blood pressure
Study 34062937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36341216 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 36341216 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33039478 — Pharmacodynamic Biomarker (PDY): Interleukin 7 receptor alpha
Genes: IL7R
Study 33039478 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 32977831 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32977831 — Surrogate Endpoint (SUR): Blood pressure
Study 32164563 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32164563 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33221776 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 35380713 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 34825307 — Predictive Biomarker (PRD): Hormone receptor
Study 32471770 — Surrogate Endpoint (SUR): Blood pressure
Study 33234638 — Surrogate Endpoint (SUR): Blood pressure
Study 35974369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32698121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32698121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36110573 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 36110573 — Predictive Biomarker (PRD): TK1 mRNA
Genes: TK1
Study 33075806 — Surrogate Endpoint (SUR): Serum uric acid
Study 35953433 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 36347387 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 36347387 — Surrogate Endpoint (SUR): Blood pressure
Study 34433000 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34582545 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32657253 — Predictive Biomarker (PRD): GPR17 mRNA
Genes: GPR17
Study 33082214 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 33082214 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 33082214 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33082214 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 33082214 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 33082214 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 32324130 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 34358343 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 32078391 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35419725 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study 32076105 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 36179725 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 32011825 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32503004 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 35834228 — Predictive Biomarker (PRD): Microsatellite instability
Study 32474427 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 34004271 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 34004271 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32447657 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 36017026 — Surrogate Endpoint (SUR): Forced vital capacity
Study 35229960 — Surrogate Endpoint (SUR): Blood pressure
Study 32866440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32866440 — Surrogate Endpoint (SUR): Forced vital capacity
Study 616039429 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 33044203 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 33242924 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 32053942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32053942 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 32053942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35147767 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 35022661 — Surrogate Endpoint (SUR): Blood pressure
Study 32313980 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 32522414 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34579104 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 34579104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32001194 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 34326995 — Surrogate Endpoint (SUR): Blood pressure
Study 35012462 — Surrogate Endpoint (SUR): Blood pressure
Study 32696033 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 32023582 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34601832 — Surrogate Endpoint (SUR): Blood pressure
Study 33350619 — Surrogate Endpoint (SUR): Blood pressure
Study 32664149 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 33071012 — Surrogate Endpoint (SUR): Blood pressure
Study 33071012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33071012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33071012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35785080 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35785080 — Surrogate Endpoint (SUR): Blood pressure
Study 34657873 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32929107 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 33205991 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32020287 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33452152 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32090748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32090748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34251414 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 35739541 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 34169526 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 35917698 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 35917698 — Monitoring Biomarker (MOI): miR-195-5p
Genes: MIR195
Study 33190559 — Surrogate Endpoint (SUR): Blood pressure
Study 33544337 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36455143 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36455143 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 34389772 — Surrogate Endpoint (SUR): Blood pressure
Study 36442202 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 36397390 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36397390 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 33768205 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 33768205 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 33768205 — Surrogate Endpoint (SUR): Total kidney volume
Study 33611847 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 32211776 — Monitoring Biomarker (MOI): HBV DNA
Study 35084243 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 35084243 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 32466187 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33636373 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 36178015 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 36178015 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34990772 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 34990772 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 34990772 — Surrogate Endpoint (SUR): Blood pressure
Study 32624568 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 33722880 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052