TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32118823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32118823 — Surrogate Endpoint (SUR): Blood pressure
Study 32382745 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 32382745 — Surrogate Endpoint (SUR): Blood pressure
Study 32202490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36174028 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36174028 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32564482 — Surrogate Endpoint (SUR): Blood pressure
Study 35115706 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32349779 — Predictive Biomarker (PRD): KMT2D mRNA
Genes: KMT2D; ALR; MLL2; MLL4
Study 32349779 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 32349779 — Predictive Biomarker (PRD): CREBBP mRNA
Genes: CREBBP; CBP
Study 32349779 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 35100493 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 35568917 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 35872936 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 35872936 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 35872936 — Safety Biomarker (SAF): miR-137
Genes: MIR137
Study 33840495 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35486013 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35486013 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 35486013 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 34299780 — Surrogate Endpoint (SUR): Blood pressure
Study 34299780 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34299780 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32542695 — Surrogate Endpoint (SUR): Bone mineral density
Study 35634695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32731259 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 32976702 — Surrogate Endpoint (SUR): Serum creatinine
Study 33883288 — Surrogate Endpoint (SUR): Blood pressure
Study 33883288 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34668331 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 34668331 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 35483774 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 35483774 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 35839004 — Surrogate Endpoint (SUR): Blood pressure
Study 34209561 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35133634 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 36049225 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35749148 — Safety Biomarker (SAF): Hyaluronic acid
Study 34656412 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33309774 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33309774 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 34452971 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 33539664 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 35724306 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 32268897 — Surrogate Endpoint (SUR): Blood pressure
Study 35221104 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35221104 — Surrogate Endpoint (SUR): Blood pressure
Study 33657976 — Surrogate Endpoint (SUR): Blood pressure
Study 33657976 — Surrogate Endpoint (SUR): Serum sodium
Study 33657976 — Surrogate Endpoint (SUR): Serum potassium
Study 33657976 — Surrogate Endpoint (SUR): Serum uric acid
Study 34407046 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33002633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33002633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34178834 — Surrogate Endpoint (SUR): Bone mineral density
Study 32113648 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 32113648 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 33806616 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 32471186 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 32471186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32471186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32471186 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 36253825 — Predictive Biomarker (PRD): COL7A1 mRNA
Genes: COL7A1
Study 36005859 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 36005859 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 36005859 — Predictive Biomarker (PRD): IGFBP2 mRNA
Genes: IGFBP2; BP2; IBP2
Study 32489675 — Surrogate Endpoint (SUR): Blood pressure
Study 35069013 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 35069013 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 35069013 — Safety Biomarker (SAF): BDNF
Study 33720857 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 32441198 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 32441198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33844054 — Surrogate Endpoint (SUR): Bone mineral density
Study 33161737 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33161737 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33317156 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 33317156 — Surrogate Endpoint (SUR): Serum creatinine
Study 32034072 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33630453 — Predictive Biomarker (PRD): PHLDA2 mRNA
Genes: PHLDA2; BWR1C; HLDA2; IPL; TSSC3
Study 36305926 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 34626502 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 32299513 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 34319398 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34741886 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34741886 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 33715064 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33715064 — Surrogate Endpoint (SUR): Blood pressure
Study 32236507 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34769704 — Surrogate Endpoint (SUR): Blood pressure
Study 32394686 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 33233275 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 35388330 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35388330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35388330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35251584 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35251584 — Surrogate Endpoint (SUR): Blood pressure
Study 32815661 — Surrogate Endpoint (SUR): Blood pressure
Study 34416229 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 35287112 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 33848805 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 34123370 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33675399 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 33675399 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 33675399 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 33675399 — Predictive Biomarker (PRD): Microsatellite instability
Study 33175128 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 34196874 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34196874 — Predictive Biomarker (PRD): Hormone receptor
Study 32985088 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32985088 — Surrogate Endpoint (SUR): Blood pressure
Study 35710594 — Surrogate Endpoint (SUR): Blood pressure
Study 32725873 — Surrogate Endpoint (SUR): Blood pressure
Study 36293771 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 33946565 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34525119 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34324472 — Surrogate Endpoint (SUR): Blood pressure
Study 34823444 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34823444 — Safety Biomarker (SAF): BDNF
Study 34803913 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34803913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34674348 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 36501009 — Surrogate Endpoint (SUR): Blood pressure
Study 32303180 — Surrogate Endpoint (SUR): Blood pressure
Study 35362378 — Surrogate Endpoint (SUR): Blood pressure
Study 33129099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33894834 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 33894834 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 33310293 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33310293 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 36197757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32048133 — Surrogate Endpoint (SUR): Blood pressure
Study 34772609 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 32343641 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 34028859 — Surrogate Endpoint (SUR): Serum sodium
Study 33078386 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 35124650 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 35124650 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 34999143 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 35793884 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 35793884 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 34279749 — Surrogate Endpoint (SUR): Blood pressure
Study 34322126 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32015461 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 32665162 — Surrogate Endpoint (SUR): Blood pressure
Study 34051428 — Surrogate Endpoint (SUR): Blood pressure
Study 33685838 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 33685838 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32620379 — Surrogate Endpoint (SUR): Blood pressure
Study 34941608 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 34188449 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35066982 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 36308124 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 33034157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34688944 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33152284 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33152284 — Predictive Biomarker (PRD): Hormone receptor
Study 33080002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34622567 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 33100131 — Predictive Biomarker (PRD): C7orf50 mRNA
Genes: C7orf50; FP15621
Study 33100131 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 33434227 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 33860313 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 34001059 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35339280 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 35339280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35339280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33755924 — Predictive Biomarker (PRD): KDM1A mRNA
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study 33755924 — Predictive Biomarker (PRD): MAOB mRNA
Genes: MAOB
Study 32644875 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32644875 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32644875 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32988567 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 32988567 — Predictive Biomarker (PRD): FUT1 mRNA
Genes: FUT1; H; HSC
Study 34269885 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34269885 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 34872102 — Surrogate Endpoint (SUR): Blood pressure
Study 33607802 — Surrogate Endpoint (SUR): Blood pressure
Study 33512079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32521891 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 35427471 — Predictive Biomarker (PRD): Microsatellite instability
Study 32459666 — Surrogate Endpoint (SUR): Blood pressure
Study 33727797 — Surrogate Endpoint (SUR): Blood pressure
Study 36460017 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32702363 — Predictive Biomarker (PRD): Hormone receptor
Study 32562310 — Safety Biomarker (SAF): miR-328a-3p
Genes: MIR328
Study 32562310 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-20a
Genes: MIR20A
Study 32562310 — Safety Biomarker (SAF): miR-17-5p
Genes: MIR17
Study 32562310 — Safety Biomarker (SAF): miR-192
Genes: MIR192
Study 32562310 — Safety Biomarker (SAF): miR-10a
Genes: MIR10A
Study 32562310 — Predictive Biomarker (PRD): miR-21-5p
Genes: MIR21
Study 32562310 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 32562310 — Monitoring Biomarker (MOI): miR-26b-5p
Genes: MIR26B
Study 34181712 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 34181712 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 34181712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33141921 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 33141921 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34185278 — Surrogate Endpoint (SUR): Serum calcium
Study 35411981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33677827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33677827 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32914569 — Surrogate Endpoint (SUR): Blood pressure
Study 35872847 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 36029105 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 33155824 — Predictive Biomarker (PRD): CLC mRNA
Genes: CLC; LGALS10; LGALS10A
Study 33891615 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33154085 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33154085 — Surrogate Endpoint (SUR): Blood pressure
Study 34277507 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34277507 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32444968 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 33793743 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 36416000 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 36194950 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35551978 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 32160755 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 33320296 — Predictive Biomarker (PRD): LARP1 mRNA
Genes: LARP1; KIAA0731; LARP
Study 33354953 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32542644 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33327746 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33327746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34791007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33221618 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 32706428 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 35979216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34906572 — Surrogate Endpoint (SUR): Blood pressure
Study 35772861 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32512234 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33217063 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 33217063 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 33064413 — Surrogate Endpoint (SUR): Blood pressure
Study 33235439 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33235439 — Surrogate Endpoint (SUR): Blood pressure
Study 35908130 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 35372992 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35372992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32021087 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 32345356 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 35135967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35135967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35922124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35922124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35508860 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 33455137 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 33020204 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33789243 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 35859277 — Surrogate Endpoint (SUR): Blood pressure
Study 32915843 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 32643361 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 32643361 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 32643361 — Predictive Biomarker (PRD): SYNM mRNA
Genes: SYNM; DMN; KIAA0353; SYN
Study 32643361 — Predictive Biomarker (PRD): KDM5D mRNA
Genes: KDM5D; HY; HYA; JARID1D; KIAA0234; SMCY
Study 34338105 — Surrogate Endpoint (SUR): Blood pressure
Study 32867959 — Surrogate Endpoint (SUR): Bone mineral density
Study 36209129 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34551895 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 33638577 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 36256912 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 33466699 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 36181009 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 36181009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33676327 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32710482 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study 32710482 — Predictive Biomarker (PRD): AXIN2 mRNA
Genes: AXIN2
Study 32422966 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 32422966 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 35776501 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35776501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34151951 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 34151951 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34151951 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32669217 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 33321526 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33038500 — Surrogate Endpoint (SUR): Blood pressure
Study 32314132 — Surrogate Endpoint (SUR): Blood pressure