TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04819243 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04758364 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06751862 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT06301451 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT06301451 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT06301451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06301451 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06301451 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT06753994 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06754852 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT05621746 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT04816214 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04816214 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04816214 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05120362 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05120362 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05069051 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT06136650 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT06554340 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05541380 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT05958719 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study NCT06430008 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT06379906 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT05695599 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05381103 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04706299 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04706299 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05136326 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT05107492 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05709301 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study NCT05709301 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT05709301 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06528847 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06528847 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04218786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00176150 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT00002324 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05081479 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05521698 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05521698 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06455709 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT06455709 — Predictive Biomarker (PRD): Anti-acetylcholine receptor antibody
Study NCT05681780 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05681780 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05681780 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT05681780 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05162677 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06435377 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT05986175 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05355974 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04872894 — Predictive Biomarker (PRD): CASR mRNA
Genes: CASR; GPRC2A; PCAR1
Study NCT04872894 — Predictive Biomarker (PRD): AP2S1 mRNA
Genes: AP2S1; AP17; CLAPS2
Study NCT05916313 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study NCT05712902 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04942366 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT06514508 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06514508 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05172817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05172817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05276726 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05276726 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study NCT04462783 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05110885 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06084949 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04864054 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT05315843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT05432401 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT06084338 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05249959 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT06236061 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06188741 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT06549452 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT06027229 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04929535 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05192148 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05047718 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05856383 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06107868 — Predictive Biomarker (PRD): PKMYT1 mRNA
Genes: PKMYT1; MYT1
Study NCT06107868 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT05854407 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study NCT06644573 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT06343220 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT05198037 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study NCT06002165 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04940338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06537414 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study NCT06537414 — Monitoring Biomarker (MOI): HBV DNA
Study NCT06684782 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT05935215 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT06375174 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study NCT05133154 — Predictive Biomarker (PRD): ATRX mRNA
Genes: ATRX; RAD54L; XH2
Study NCT05133154 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04625699 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06682390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06682390 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06682390 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT04778033 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT06056024 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06684990 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT05922462 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05072106 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05532358 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT05532358 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05060549 — Safety Biomarker (SAF): DRD3
Study NCT05871320 — Predictive Biomarker (PRD): SSTR2 mRNA
Genes: SSTR2
Study NCT05034159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06756620 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study NCT06757335 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06451133 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06447987 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06757309 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05324085 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05324085 — Safety Biomarker (SAF): BDNF
Study NCT06667830 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT04699279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05441072 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT06041035 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT05293665 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06758310 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06458413 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05067517 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02451852 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02451852 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05119179 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study NCT05119179 — Predictive Biomarker (PRD): GLP1R mRNA
Genes: GLP1R
Study NCT04731298 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study NCT04731298 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT06336356 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT06682988 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT06688799 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06716658 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT06718335 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06728865 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06685315 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study NCT06685315 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study NCT06685042 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06684132 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT06224127 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT06037460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05714969 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT05091177 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT05091177 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05091177 — Monitoring Biomarker (MOI): Complement C4
Study NCT06199089 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT04364958 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT06343727 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT06111105 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06313437 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT06653127 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT05316272 — Predictive Biomarker (PRD): BMF mRNA
Genes: BMF
Study NCT05316272 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05846646 — Predictive Biomarker (PRD): STING1 mRNA
Genes: STING1; ERIS; MITA; STING; TMEM173
Study NCT05789069 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study NCT05829434 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study NCT06732011 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06741722 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06741566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05246774 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT05246774 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2
Study NCT05246774 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT05246774 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05246774 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT05246774 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study NCT05246774 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06755697 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05334316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05028218 — Predictive Biomarker (PRD): CDC7 mRNA
Genes: CDC7; CDC7L1
Study NCT04118153 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04118153 — Predictive Biomarker (PRD): EOMES mRNA
Genes: EOMES; TBR2
Study NCT04118153 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05582421 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT05183789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05183789 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT05766410 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04946890 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT06085495 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study NCT05490342 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05135494 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT05852704 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05897008 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT04752826 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study NCT06224738 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06224738 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05039788 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05885672 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05323240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05054803 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05072080 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06640361 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study NCT04824495 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06305793 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06305793 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05027139 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05027139 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05239741 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT06353321 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04276116 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT05323955 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05323955 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05323955 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06365788 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT05877898 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05926180 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05926180 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT05926180 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study NCT05926180 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05926180 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06561698 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT05982795 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT05695586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05867277 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05681962 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04949243 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05668741 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT05356858 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04489134 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04489134 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT04939363 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT04939363 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT04939363 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study NCT04939363 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT04939363 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT06714851 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06729099 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05981742 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT04808752 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05415670 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05344664 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT05870839 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06297590 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05107128 — Predictive Biomarker (PRD): SAGE1 mRNA
Genes: SAGE1; SAGE
Study NCT05107128 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT04744545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04744545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04903392 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06395818 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06634823 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT05162573 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06568432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06265428 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06133751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06062251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04816227 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT05166109 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study NCT06649292 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT06256237 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study NCT06256237 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05890989 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05529693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05529693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05668910 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05724745 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06436898 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT05670730 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT05092672 — Surrogate Endpoint (SUR): Blood pressure