TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT06778122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06778122 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04697862 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT04697862 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06275919 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06275919 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT06275919 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT06275919 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT05373004 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05373004 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT06778356 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05141253 — Predictive Biomarker (PRD): MSLN mRNA
Genes: MSLN; MPF
Study NCT05450601 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06712966 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04711109 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06135714 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06135714 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06492616 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06492616 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06558149 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05517083 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05298657 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT05946759 — Predictive Biomarker (PRD): HYLS1 mRNA
Genes: HYLS1; HLS
Study NCT06708312 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06552052 — Predictive Biomarker (PRD): ACTA2 mRNA
Genes: ACTA2; ACTSA; ACTVS; GIG46
Study NCT05515042 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06714123 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05010122 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT04794985 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06712875 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06712875 — Predictive Biomarker (PRD): KIAA1549 mRNA
Genes: KIAA1549
Study NCT06713161 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT06609356 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05123924 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04379570 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06680596 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06680596 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06680596 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06634173 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06634173 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT04454203 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06293677 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06467799 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05782881 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05005897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT06552338 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04194632 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04513288 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study NCT04312516 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05998863 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05769010 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06712030 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT05571670 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT05486013 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05356741 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06500208 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06500208 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06500208 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04644549 — Predictive Biomarker (PRD): CLN6 mRNA
Genes: CLN6
Study NCT04644549 — Predictive Biomarker (PRD): CLN3 mRNA
Genes: CLN3; BTS
Study NCT06778967 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT06778018 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06777537 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06777537 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05997732 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05636397 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study NCT05241860 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT06323148 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06452979 — Predictive Biomarker (PRD): NSMF mRNA
Genes: NSMF; NELF
Study NCT04876365 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT06216678 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05693974 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT05916274 — Predictive Biomarker (PRD): STING1 mRNA
Genes: STING1; ERIS; MITA; STING; TMEM173
Study NCT04710979 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06179303 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06179303 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06179303 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04851873 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT04941027 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT06101303 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04803201 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT06343402 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06421883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06421883 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05060744 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06079567 — Predictive Biomarker (PRD): SMCHD1 mRNA
Genes: SMCHD1; KIAA0650
Study NCT05706883 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05917600 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05142397 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT05734612 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT05734612 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study NCT05622240 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05934630 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT06169176 — Safety Biomarker (SAF): Th2 cell
Study NCT06680232 — Monitoring Biomarker (MOI): HBV DNA
Study NCT06629831 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT06629831 — Safety Biomarker (SAF): Platelet to lymphocyte
Study NCT00000812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06775314 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06123988 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06123988 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05683067 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04657211 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT03662633 — Predictive Biomarker (PRD): SEMA4C mRNA
Genes: SEMA4C; KIAA1739; SEMAI; UNQ5855/PRO34487
Study NCT05308264 — Predictive Biomarker (PRD): IRAK1 mRNA
Genes: IRAK1; IRAK
Study NCT06346886 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06467357 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04474847 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT06325748 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT06325748 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05303792 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT05655520 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT06121297 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06450314 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06450314 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06128564 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04686019 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT05939167 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06581432 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04586452 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study NCT05733611 — Predictive Biomarker (PRD): RP2 mRNA
Genes: RP2
Study NCT06417814 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06634238 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04604067 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study NCT04604067 — Predictive Biomarker (PRD): CD79A mRNA
Genes: CD79A; IGA; MB1
Study NCT06319196 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study NCT05604989 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05856331 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT06254482 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT05870579 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT05870579 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05870579 — Predictive Biomarker (PRD): GRPR mRNA
Genes: GRPR
Study NCT05870579 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05870579 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05160168 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT06638645 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT05554341 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT05496322 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04806347 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04742387 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06109467 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06544330 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05685004 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT05019508 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study NCT06016023 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT05456503 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT06223087 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT05128760 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05437315 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05439083 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04283604 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06508320 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06508320 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06271330 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05393024 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT06163859 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06483490 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT06483490 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT05648188 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study NCT06148467 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT05599360 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT05599360 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT06058429 — Predictive Biomarker (PRD): CA6 mRNA
Genes: CA6
Study NCT06058429 — Predictive Biomarker (PRD): CA10 mRNA
Genes: CA10; hucep-15; UNQ533/PRO1076
Study NCT05373628 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05373628 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT06318585 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT05481437 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT05173441 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06229548 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05575206 — Predictive Biomarker (PRD): ELAPOR1 mRNA
Genes: ELAPOR1; EIG121; KIAA1324; UNQ2426/PRO4985
Study NCT05575206 — Predictive Biomarker (PRD): ELAPOR2 mRNA
Genes: ELAPOR2; EIG121L; KIAA1324L
Study NCT05057806 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05412355 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT05092984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06633770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06633770 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT06633770 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT05469490 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study NCT05802355 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06041789 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04674956 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05944432 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05738278 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05138991 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04832009 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06463002 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05295589 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT06550466 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04809233 — Predictive Biomarker (PRD): HRAS mRNA
Genes: HRAS; HRAS1
Study NCT05872295 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04793568 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT04774497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04774497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04774497 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT06125977 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06125977 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT05097365 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study NCT05097365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT06006390 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT03960125 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study NCT05232812 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT05281705 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06570187 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06633692 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05235711 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT06033092 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT06033092 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06033092 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT06033092 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT06033092 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study NCT06033092 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study NCT06033092 — Predictive Biomarker (PRD): RAD51C mRNA
Genes: RAD51C; RAD51L2
Study NCT05605769 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06414304 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT05344976 — Predictive Biomarker (PRD): MSLN mRNA
Genes: MSLN; MPF
Study NCT05263817 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05263817 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05651607 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT05700864 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04691154 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04846894 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT06019923 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT06019923 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study NCT05642000 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05076214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05076214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05076214 — Safety Biomarker (SAF): BDNF
Study NCT05096832 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04399486 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06064240 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06064240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05263830 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT06063330 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05055583 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05108402 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05608863 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05871021 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05871021 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT05296863 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT05983432 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05994807 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05426460 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT00004855 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06379126 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study NCT06379126 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT05404334 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT05404334 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT05404334 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT05404334 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06088030 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT04895098 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT04895098 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05926713 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT06021626 — Predictive Biomarker (PRD): STING1 mRNA
Genes: STING1; ERIS; MITA; STING; TMEM173
Study NCT06633289 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT05344027 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study NCT05344027 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study NCT06490679 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT04758858 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06520163 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06520163 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT06096805 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study NCT06361121 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study NCT05980689 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05980689 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT05850364 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06292117 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT05607654 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06474208 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05368064 — Predictive Biomarker (PRD): RUNX2 mRNA
Genes: RUNX2; AML3; CBFA1; OSF2; PEBP2A
Study NCT06344767 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04537832 — Predictive Biomarker (PRD): SCN1A mRNA
Genes: SCN1A; NAC1; SCN1
Study NCT05711368 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728