TrialPanorama/TrialPanorama-database huggingface dataset:
Study 32641418 — Predictive Biomarker (PRD): FCN2 mRNA
Genes: FCN2; FCNL
Study 32641418 — Safety Biomarker (SAF): C-C motif chemokine 19
Genes: CCL19; ELC; MIP3B; SCYA19
Study 32641418 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 32641418 — Predictive Biomarker (PRD): FETUB mRNA
Genes: FETUB
Study 32642149 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 32642149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32642149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32642149 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32642592 — Safety Biomarker (SAF): Coagulation factor Va
Genes: F5
Study 32642592 — Monitoring Biomarker (MOI): HBV DNA
Study 32642992 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32644818 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 32645016 — Predictive Biomarker (PRD): Induced myeloid leukemia cell differentiation protein Mcl-1
Genes: MCL1; BCL2L3
Study 32645016 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 32645016 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 32645282 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 32645282 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 32645282 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 32645640 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 32645640 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32646369 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 32646955 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 32647975 — Surrogate Endpoint (SUR): Serum calcium
Study 32648087 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 32648087 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 32648205 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 32648205 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 32649004 — Surrogate Endpoint (SUR): Pathological complete response
Study 32650781 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32652034 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 32652442 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study 32652442 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 32653053 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32654183 — Predictive Biomarker (PRD): ALPL mRNA
Genes: ALPL
Study 32654183 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 32657505 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32657505 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32657973 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32658300 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32659272 — Predictive Biomarker (PRD): BMAL1 mRNA
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study 32659272 — Predictive Biomarker (PRD): PER2 mRNA
Genes: PER2; KIAA0347
Study 32659272 — Predictive Biomarker (PRD): PER1 mRNA
Genes: PER1; KIAA0482; PER; RIGUI
Study 32659272 — Predictive Biomarker (PRD): PER3 mRNA
Genes: PER3; GIG13
Study 32659786 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 32660470 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 32660613 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 32660613 — Surrogate Endpoint (SUR): Blood pressure
Study 32661003 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 32661186 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 32661295 — Predictive Biomarker (PRD): NRM mRNA
Genes: NRM; NRM29; UNQ555/PRO1112
Study 32661752 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32661752 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 32662758 — Surrogate Endpoint (SUR): Bone mineral density
Study 32664901 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32665314 — Surrogate Endpoint (SUR): Serum creatinine
Study 32665855 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 32665855 — Surrogate Endpoint (SUR): Pathological complete response
Study 32667265 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 32667729 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 32667729 — Surrogate Endpoint (SUR): Blood pressure
Study 32669548 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32670418 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 32671100 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 32671831 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 32671831 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32671831 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32672790 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32673385 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 32674336 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 32674634 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 32674634 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32675047 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32677968 — Predictive Biomarker (PRD): SLC25A10 mRNA
Genes: SLC25A10; DIC
Study 32680480 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32681140 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 32681659 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 32681682 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 32681682 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 32681700 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 32681700 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 32681700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32682441 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 32682718 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 32682714 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32683101 — Predictive Biomarker (PRD): LAMB2 mRNA
Genes: LAMB2; LAMS
Study 32683528 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 32683528 — Predictive Biomarker (PRD): MARCKS mRNA
Genes: MARCKS; MACS; PRKCSL
Study 32683763 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32684363 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 32686047 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 32690246 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32690535 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 32690535 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 32690535 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 32690535 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 32690727 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 32690731 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 32690786 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 32692450 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 32692450 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 32692450 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 32692850 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32692850 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 32693406 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 32693406 — Safety Biomarker (SAF): Reactive oxygen species
Study 32694147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32694159 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32694159 — Predictive Biomarker (PRD): Hormone receptor
Study 32695960 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 32696319 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 32696319 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32696441 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 32696441 — Predictive Biomarker (PRD): SLCO3A1 mRNA
Genes: SLCO3A1; OATP3A1; OATPD; SLC21A11
Study 32698195 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 32698532 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 32699166 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32700260 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 32700765 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32700765 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32700765 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32700765 — Predictive Biomarker (PRD): Hormone receptor
Study 32701411 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 32701811 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32702156 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 32702156 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 32702570 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32702570 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 32704173 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 32704173 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): IL21 mRNA
Genes: IL21
Study 32704173 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 32704557 — Predictive Biomarker (PRD): THEMIS mRNA
Genes: THEMIS; C6orf190; C6orf207
Study 32706533 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 32706636 — Predictive Biomarker (PRD): Hormone receptor
Study 32709235 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 32710011 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 32710922 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32710922 — Predictive Biomarker (PRD): CD8A mRNA
Genes: CD8A; MAL
Study 32710922 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study 32710922 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 32711542 — Predictive Biomarker (PRD): RASL12 mRNA
Genes: RASL12; RIS
Study 32711747 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32713940 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32714408 — Predictive Biomarker (PRD): EIF2AK3 mRNA
Genes: EIF2AK3; PEK; PERK
Study 32714408 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 32714423 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32715396 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 32715736 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-34a
Genes: MIR34A
Study 32715844 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 32716707 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32716740 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32717265 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 32717315 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32717408 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 32718876 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32718876 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 32718876 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32718876 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 32718997 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32718997 — Predictive Biomarker (PRD): Hormone receptor
Study 32719417 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 32719455 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 32719455 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 32719915 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 32720012 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32722801 — Surrogate Endpoint (SUR): Blood pressure
Study 32723735 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 32725443 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 32727600 — Predictive Biomarker (PRD): ACVR1 mRNA
Genes: ACVR1; ACVRLK2
Study 32728595 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32728595 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32728965 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32730305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32730586 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 32730586 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 32730756 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32732224 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32732303 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 32732355 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32732355 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32732380 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 32733600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32733600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32733902 — Predictive Biomarker (PRD): TRIM37 mRNA
Genes: TRIM37; KIAA0898; MUL; POB1
Study 32734204 — Surrogate Endpoint (SUR): Blood pressure
Study 32734251 — Surrogate Endpoint (SUR): Blood pressure
Study 32734695 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32735048 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32735111 — Surrogate Endpoint (SUR): Blood pressure
Study 32735836 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 32736411 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 32736411 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 32736543 — Predictive Biomarker (PRD): LSAMP mRNA
Genes: LSAMP; IGLON3; LAMP
Study 32737003 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 32737707 — Surrogate Endpoint (SUR): Blood pressure
Study 32737717 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 32737717 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 32737717 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 32738042 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 32738255 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32738404 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 32740083 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 32741616 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study 32741971 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 32742241 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 32743009 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 32743852 — Surrogate Endpoint (SUR): Blood pressure
Study 32743852 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32744105 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 32744105 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 32744105 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32745961 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32746820 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 32746839 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32746884 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study 32746884 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 32746884 — Predictive Biomarker (PRD): GPAA1 mRNA
Genes: GPAA1; GAA1
Study 32748394 — Surrogate Endpoint (SUR): Blood pressure
Study 32749224 — Surrogate Endpoint (SUR): Blood pressure
Study 32749716 — Predictive Biomarker (PRD): SUMF1 mRNA
Genes: SUMF1; PSEC0152; UNQ3037/PRO9852
Study 32750295 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32750295 — Safety Biomarker (SAF): Reactive oxygen species
Study 32750311 — Surrogate Endpoint (SUR): Blood pressure
Study 32750501 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 32750501 — Predictive Biomarker (PRD): INSM1 mRNA
Genes: INSM1; IA1
Study 32750501 — Predictive Biomarker (PRD): MAPK8IP2 mRNA
Genes: MAPK8IP2; IB2; JIP2; PRKM8IPL
Study 32753397 — Predictive Biomarker (PRD): NEU1 mRNA
Genes: NEU1; NANH
Study 32753543 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 32753546 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32753546 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32753879 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32755471 — Surrogate Endpoint (SUR): Blood pressure
Study 32755608 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 32755891 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32757853 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32758434 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 32759248 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 32759249 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32759265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32759300 — Monitoring Biomarker (MOI): HBV DNA
Study 32759360 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 32759360 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 32761088 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32761193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32761193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32761193 — Safety Biomarker (SAF): Hyaluronic acid
Study 32761193 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 32762394 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 32764775 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 32764775 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32766469 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 32766875 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 32766875 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32766890 — Predictive Biomarker (PRD): SRY mRNA
Genes: SRY; TDF
Study 32767054 — Predictive Biomarker (PRD): SAGE1 mRNA
Genes: SAGE1; SAGE
Study 32767997 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 32769752 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 32770263 — Predictive Biomarker (PRD): CA6 mRNA
Genes: CA6
Study 32770720 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 32771088 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 32771088 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 32772769 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32773243 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32774889 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 32776402 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 32776402 — Safety Biomarker (SAF): BDNF
Study 32776402 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 32776632 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 32778095 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 32778095 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 32778095 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study 32778095 — Predictive Biomarker (PRD): FANCA mRNA
Genes: FANCA; FAA; FACA; FANCH
Study 32778095 — Predictive Biomarker (PRD): FANCB mRNA
Genes: FANCB
Study 32778095 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 32778095 — Predictive Biomarker (PRD): FANCF mRNA
Genes: FANCF
Study 32778095 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study 32778095 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study 32778146 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32778827 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 32778827 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32779037 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32779705 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32779863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32779863 — Safety Biomarker (SAF): Interleukin 1
Study 32779947 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 32780026 — Surrogate Endpoint (SUR): Blood pressure
Study 32780660 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK