TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33423006 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 33423006 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 32013045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33560235 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 32702867 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32154636 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 35907513 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32948827 — Surrogate Endpoint (SUR): Blood pressure
Study 32943033 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study 32943033 — Predictive Biomarker (PRD): DEF8 mRNA
Genes: DEF8
Study 32943033 — Predictive Biomarker (PRD): H1-2 mRNA
Genes: H1-2; H1F2; HIST1H1C
Study 32943033 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 32943033 — Predictive Biomarker (PRD): CHFR mRNA
Genes: CHFR; RNF196
Study 32846782 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33126534 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33126534 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34158598 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34158598 — Predictive Biomarker (PRD): Hormone receptor
Study 35284808 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 34011035 — Surrogate Endpoint (SUR): Serum creatinine
Study 34011035 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 32128848 — Surrogate Endpoint (SUR): Blood pressure
Study 32464421 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 36099091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36099091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32472001 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32472001 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 33532956 — Surrogate Endpoint (SUR): Blood pressure
Study 36036107 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 32423457 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36070590 — Surrogate Endpoint (SUR): Serum creatinine
Study 33390654 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 36216309 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 36216309 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 36216309 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 33533820 — Predictive Biomarker (PRD): ASPSCR1 mRNA
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 36290823 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34382434 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 33038338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33038338 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 33038338 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 33038338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33038338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33038338 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32925908 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 34363558 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 32164886 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35297744 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 35063242 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 32622610 — Predictive Biomarker (PRD): HTR4 mRNA
Genes: HTR4
Study 32622610 — Predictive Biomarker (PRD): SLC4A4 mRNA
Genes: SLC4A4; NBC; NBC1; NBCE1
Study 32622610 — Predictive Biomarker (PRD): HTR2B mRNA
Genes: HTR2B
Study 33788296 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 35606010 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 35308141 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 35308141 — Safety Biomarker (SAF): Urinary microalbumin
Study 35761219 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32183736 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 32183736 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 33514329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33514329 — Predictive Biomarker (PRD): IL1RN mRNA
Genes: IL1RN; IL1F3; IL1RA
Study 32018062 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 36235569 — Predictive Biomarker (PRD): BSG mRNA
Genes: BSG; UNQ6505/PRO21383
Study 35512620 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 32802833 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 36335191 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 32144319 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32144319 — Surrogate Endpoint (SUR): Blood pressure
Study 32144319 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36173415 — Surrogate Endpoint (SUR): Bone mineral density
Study 35862120 — Surrogate Endpoint (SUR): Blood pressure
Study 35726351 — Surrogate Endpoint (SUR): Blood pressure
Study 34195988 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 34195988 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 32545056 — Surrogate Endpoint (SUR): Blood pressure
Study 36102943 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 33044684 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 33044684 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 33596883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35738494 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 35738494 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 35738494 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 34403608 — Surrogate Endpoint (SUR): Blood pressure
Study 33704351 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33554371 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 32513231 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33151364 — Predictive Biomarker (PRD): CORIN mRNA
Genes: CORIN; CRN; TMPRSS10
Study 34961793 — Surrogate Endpoint (SUR): Serum potassium
Study 33234846 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36388925 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36388925 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34961418 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35258533 — Surrogate Endpoint (SUR): Blood pressure
Study 32301053 — Surrogate Endpoint (SUR): Blood pressure
Study 32314939 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 36141488 — Surrogate Endpoint (SUR): Bone mineral density
Study 34595804 — Surrogate Endpoint (SUR): Blood pressure
Study 33189900 — Predictive Biomarker (PRD): TRPV4 mRNA
Genes: TRPV4; VRL2; VROAC
Study 32197373 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32197373 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34989804 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35240678 — Surrogate Endpoint (SUR): Blood pressure
Study 34674750 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33506798 — Safety Biomarker (SAF): Hyaluronic acid
Study 32529811 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study 33206786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33206786 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32520900 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 33783488 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36271193 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 36271193 — Surrogate Endpoint (SUR): Blood pressure
Study 32681996 — Safety Biomarker (SAF): Hyaluronic acid
Study 33385417 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 33385417 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 33385417 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 35667065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35661487 — Predictive Biomarker (PRD): POSTN mRNA
Genes: POSTN; OSF2
Study 35661487 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 616774602 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 35648053 — Predictive Biomarker (PRD): TNNT1 mRNA
Genes: TNNT1; TNT
Study 35648053 — Predictive Biomarker (PRD): AWAT2 mRNA
Genes: AWAT2; DC4; DGAT2L4; MFAT; WS
Study 34264439 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 34264439 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 34264439 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 34264439 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 36052414 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 36052414 — Safety Biomarker (SAF): Platelet to lymphocyte
Study 33302270 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35253582 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 35101086 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 34579146 — Surrogate Endpoint (SUR): Blood pressure
Study 33119156 — Surrogate Endpoint (SUR): Bone mineral density
Study 35241003 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 36200674 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 32407216 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33983512 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 33983512 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 32164439 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 32679568 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35384630 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32398304 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 34865278 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 33804738 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33804738 — Surrogate Endpoint (SUR): Blood pressure
Study 34321278 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34321278 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 34990776 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32707342 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 32556481 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 36253765 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 36404171 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32059710 — Predictive Biomarker (PRD): NRF1 mRNA
Genes: NRF1
Study 36079806 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 33814247 — Surrogate Endpoint (SUR): Blood pressure
Study 34124840 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 34258913 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 34258913 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34284351 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 36132545 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32734461 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 33455117 — Predictive Biomarker (PRD): WWOX mRNA
Genes: WWOX; FOR; SDR41C1; WOX1
Study 32363972 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 35728875 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 35728875 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35728875 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 35728875 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 35728875 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36418750 — Safety Biomarker (SAF): miR-142
Genes: MIR142
Study 35940738 — Safety Biomarker (SAF): Hyaluronic acid
Study 32712103 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32892184 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 35711602 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35657028 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 35657028 — Predictive Biomarker (PRD): NELFCD mRNA
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 32042073 — Surrogate Endpoint (SUR): Blood pressure
Study 32398091 — Surrogate Endpoint (SUR): Blood pressure
Study 36271264 — Surrogate Endpoint (SUR): Bone mineral density
Study 33568343 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 35335885 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 35335885 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 32410705 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32503662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32503662 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33316649 — Predictive Biomarker (PRD): L1CAM mRNA
Genes: L1CAM; CAML1; MIC5
Study 33316649 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 33316649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33022918 — Surrogate Endpoint (SUR): Blood pressure
Study 33022918 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34216468 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32009491 — Surrogate Endpoint (SUR): Blood pressure
Study 35449818 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35449818 — Surrogate Endpoint (SUR): Blood pressure
Study 32022434 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 35501846 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35501846 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35645070 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 32608989 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 32868138 — Surrogate Endpoint (SUR): Pathological complete response
Study 32791048 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 32456512 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33471240 — Surrogate Endpoint (SUR): Total kidney volume
Study 35997713 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 35256446 — Surrogate Endpoint (SUR): Blood pressure
Study 32443139 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 33974725 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33974725 — Surrogate Endpoint (SUR): Blood pressure
Study 32529467 — Predictive Biomarker (PRD): APEX1 mRNA
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 33278562 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 34024811 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 33232804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32496365 — Surrogate Endpoint (SUR): Blood pressure
Study 32496365 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34752723 — Safety Biomarker (SAF): Hyaluronic acid
Study 33969434 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 33969434 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35751895 — Surrogate Endpoint (SUR): Bone mineral density
Study 36011639 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 32447858 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 32447858 — Predictive Biomarker (PRD): FBXO8 mRNA
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 34528132 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 33185325 — Monitoring Biomarker (MOI): HBV DNA
Study 35323106 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 36004709 — Surrogate Endpoint (SUR): Blood pressure
Study 34774485 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 35016629 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 35016629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35016629 — Safety Biomarker (SAF): BDNF
Study 33132345 — Surrogate Endpoint (SUR): Blood pressure
Study 34391532 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34391532 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32209963 — Surrogate Endpoint (SUR): Blood pressure
Study 35660501 — Predictive Biomarker (PRD): SQSTM1 mRNA
Genes: SQSTM1; ORCA; OSIL
Study 35660501 — Predictive Biomarker (PRD): LAMP2 mRNA
Genes: LAMP2
Study 33196574 — Surrogate Endpoint (SUR): Blood pressure
Study 32147362 — Predictive Biomarker (PRD): MAP3K5 mRNA
Genes: MAP3K5; ASK1; MAPKKK5; MEKK5
Study 36246987 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36246987 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 36334013 — Surrogate Endpoint (SUR): Blood pressure
Study 36414931 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 33770195 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 33770195 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33583066 — Surrogate Endpoint (SUR): Blood pressure
Study 35325622 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 35338353 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 35845740 — Safety Biomarker (SAF): IL-6 and IL-10
Study 32360666 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 35379563 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33570647 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 33955229 — Surrogate Endpoint (SUR): Blood pressure
Study 35501676 — Surrogate Endpoint (SUR): Blood pressure
Study 32249637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32249637 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 32249637 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 34360036 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33819336 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 36149935 — Safety Biomarker (SAF): miR-1
Study 36149935 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 34156521 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 34787258 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32388647 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 33485731 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33485731 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33485731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33485731 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 33220095 — Surrogate Endpoint (SUR): Blood pressure
Study 36474274 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35435086 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 35435086 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 35435086 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 35435086 — Surrogate Endpoint (SUR): Blood pressure
Study 35435086 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35435086 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33373480 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 36082590 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 32438817 — Surrogate Endpoint (SUR): Blood pressure
Study 33472269 — Surrogate Endpoint (SUR): Blood pressure
Study 34563178 — Surrogate Endpoint (SUR): Blood pressure
Study 34563178 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34655181 — Surrogate Endpoint (SUR): Blood pressure
Study 33432829 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 33432829 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33211212 — Surrogate Endpoint (SUR): Bone mineral density
Study 32012080 — Surrogate Endpoint (SUR): Blood pressure
Study 32012080 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32859638 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32859638 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 32859638 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 32859638 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 34001053 — Surrogate Endpoint (SUR): Blood pressure
Study 33657083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34861036 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK