TrialPanorama/TrialPanorama-database huggingface dataset:
Study 35482774 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33666264 — Surrogate Endpoint (SUR): Blood pressure
Study 34795574 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 33337693 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Sclerostin
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study 32303745 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 33845931 — Surrogate Endpoint (SUR): Blood pressure
Study 34413142 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35141317 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35260800 — Predictive Biomarker (PRD): STK4 mRNA
Genes: STK4; KRS2; MST1
Study 33934120 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 34058081 — Surrogate Endpoint (SUR): Blood pressure
Study 32746736 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 32050899 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study 32768465 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32768465 — Surrogate Endpoint (SUR): Blood pressure
Study 34362491 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 33068876 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 36564573 — Safety Biomarker (SAF): Hyaluronic acid
Study 33668674 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 35649684 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35369650 — Surrogate Endpoint (SUR): Serum uric acid
Study 32912989 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34107529 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34107529 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 32934137 — Surrogate Endpoint (SUR): Serum uric acid
Study 33909172 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 33909172 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 35707040 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 35707040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35557088 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 35557088 — Surrogate Endpoint (SUR): Blood pressure
Study 35904872 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 34127852 — Surrogate Endpoint (SUR): Blood pressure
Study 36089068 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 36125471 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33548492 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 32178964 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 36283011 — Surrogate Endpoint (SUR): Serum calcium
Study 32727707 — Predictive Biomarker (PRD): MTLN mRNA
Genes: MTLN; LEMP; LINC00116; MOXI; MPM; NCRNA00116; SMIM37
Study 34102253 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34102253 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34102253 — Predictive Biomarker (PRD): Hormone receptor
Study 34362490 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 34362490 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 34362490 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 34246347 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 32311957 — Surrogate Endpoint (SUR): Blood pressure
Study 33180910 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 34000227 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32962477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33929379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35836627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33920292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33920292 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 33920292 — Predictive Biomarker (PRD): ADORA2A mRNA
Genes: ADORA2A; ADORA2
Study 33920292 — Predictive Biomarker (PRD): PER3 mRNA
Genes: PER3; GIG13
Study 32652314 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32652314 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32610495 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 32610495 — Predictive Biomarker (PRD): TPH2 mRNA
Genes: TPH2; NTPH
Study 32610495 — Predictive Biomarker (PRD): TDO2 mRNA
Genes: TDO2; TDO
Study 32067684 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 34077818 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 32466854 — Surrogate Endpoint (SUR): Serum calcium
Study 35560498 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 33433575 — Surrogate Endpoint (SUR): Blood pressure
Study 35567859 — Surrogate Endpoint (SUR): Blood pressure
Study 34764381 — Surrogate Endpoint (SUR): Blood pressure
Study 35405352 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 33885257 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33885257 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 33885257 — Surrogate Endpoint (SUR): Blood pressure
Study 33863270 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 33763470 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 32820851 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 35437945 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 33828241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 35924110 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 36112723 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 36112723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36112723 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 34179971 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 33374791 — Safety Biomarker (SAF): Hyaluronic acid
Study 33974920 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 36477362 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 36477362 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 34195880 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34195880 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32716115 — Safety Biomarker (SAF): Hyaluronic acid
Study 35524760 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34974019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34974019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34974019 — Surrogate Endpoint (SUR): Blood pressure
Study 36368945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36368945 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 32458506 — Surrogate Endpoint (SUR): Sperm parameters
Study 35340225 — Predictive Biomarker (PRD): SLC25A20 mRNA
Genes: SLC25A20; CAC; CACT
Study 35340225 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 33280783 — Surrogate Endpoint (SUR): Blood pressure
Study 32462427 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 33545758 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 33647042 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 33647042 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 33647042 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32096667 — Predictive Biomarker (PRD): IHH mRNA
Genes: IHH
Study 33710815 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 34562262 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 32187462 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33164983 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 33947344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33947344 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35578182 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35569036 — Predictive Biomarker (PRD): PDE4B mRNA
Genes: PDE4B; DPDE4
Study 35569036 — Surrogate Endpoint (SUR): Forced vital capacity
Study 32927476 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 32927476 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 33497862 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 33497862 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33406977 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 33559444 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 33559444 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33548080 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 33548080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32347766 — Surrogate Endpoint (SUR): Blood pressure
Study 33127971 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 34319944 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 34319944 — Surrogate Endpoint (SUR): Blood pressure
Study 32506124 — Safety Biomarker (SAF): Hyaluronic acid
Study 32699167 — Surrogate Endpoint (SUR): Blood pressure
Study 32883231 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 34050932 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 35294545 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 35294545 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 32402702 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 32928582 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 32607949 — Predictive Biomarker (PRD): FLT3
Genes: STK1; FLK2; CD135
Study 32607949 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 32607949 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 32607949 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 34990777 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34264698 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 35723127 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 35723127 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 34248142 — Predictive Biomarker (PRD): STING1 mRNA
Genes: STING1; ERIS; MITA; STING; TMEM173
Study 34248142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34248142 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34248142 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 34375135 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 34375135 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 35844038 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 34377197 — Surrogate Endpoint (SUR): Blood pressure
Study 34119628 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34119628 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 33751401 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 36260859 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 35998768 — Predictive Biomarker (PRD): Hormone receptor
Study 32873964 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 32873964 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study 34260836 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 34260836 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 36050695 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 36050695 — Surrogate Endpoint (SUR): Serum triglycerides
Study 36050695 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36050695 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33978350 — Surrogate Endpoint (SUR): Blood pressure
Study 34427681 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33232588 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32475159 — Surrogate Endpoint (SUR): Blood pressure
Study 33170239 — Surrogate Endpoint (SUR): Blood pressure
Study 34061314 — Surrogate Endpoint (SUR): Blood pressure
Study 34788569 — Surrogate Endpoint (SUR): Blood pressure
Study 34788569 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34788569 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34034748 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 33380521 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 33962041 — Monitoring Biomarker (MOI): HBV DNA
Study 33962041 — Surrogate Endpoint (SUR): Bone mineral density
Study 33962041 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33962041 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35394821 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 35394821 — Surrogate Endpoint (SUR): Serum potassium
Study 32187150 — Surrogate Endpoint (SUR): Blood pressure
Study 33673568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33673568 — Surrogate Endpoint (SUR): Serum calcium
Study 32111770 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 34690787 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study 36123073 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 33635903 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32545478 — Surrogate Endpoint (SUR): Blood pressure
Study 35929990 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 32631387 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 32631387 — Predictive Biomarker (PRD): NOL11 mRNA
Genes: NOL11; L14
Study 32631387 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 35560696 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 35560696 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33208593 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 33208593 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32025848 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 36107549 — Surrogate Endpoint (SUR): Blood pressure
Study 35584738 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 34494355 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 34494355 — Predictive Biomarker (PRD): SCAI mRNA
Genes: SCAI; C9orf126
Study 33724919 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33012596 — Surrogate Endpoint (SUR): Blood pressure
Study 36164038 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 35594968 — Surrogate Endpoint (SUR): Blood pressure
Study 33792210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33792210 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 32687451 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 33245453 — Predictive Biomarker (PRD): TEAD1 mRNA
Genes: TEAD1; TCF13; TEF1
Study 32513307 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 35486411 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 33420673 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 33228739 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 35422138 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 34154367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34154367 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35614404 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 34506883 — Safety Biomarker (SAF): Interleukin 1
Study 34506883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34506883 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 35151715 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33906005 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36053969 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 36053969 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 32186028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36026800 — Surrogate Endpoint (SUR): Blood pressure
Study 34290862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33629548 — Predictive Biomarker (PRD): ANO1 mRNA
Genes: ANO1; DOG1; ORAOV2; TAOS2; TMEM16A
Study 32385918 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 36449307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 36449307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34185116 — Predictive Biomarker (PRD): GLCCI1 mRNA
Genes: GLCCI1
Study 33966029 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 36071112 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 36071112 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 33989797 — Surrogate Endpoint (SUR): Blood pressure
Study 37902943 — Predictive Biomarker (PRD): CLK1 mRNA
Genes: CLK1; CLK
Study 37902943 — Predictive Biomarker (PRD): DYRK1A mRNA
Genes: DYRK1A; DYRK; MNB; MNBH
Study 35769196 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 35769196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35769196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35769196 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 35769196 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 35769196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35769196 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 35769196 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 35769196 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 32235690 — Surrogate Endpoint (SUR): Blood pressure
Study 32530765 — Predictive Biomarker (PRD): CILP mRNA
Genes: CILP; UNQ602/PRO1188
Study 32530765 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 33529381 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 33594103 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33538237 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 36043781 — Surrogate Endpoint (SUR): Blood pressure
Study 33966361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 616117489 — Surrogate Endpoint (SUR): Blood pressure
Study 36056374 — Surrogate Endpoint (SUR): Pathological complete response
Study 34335943 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 34335943 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 34335943 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34335943 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 34335943 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 35051162 — Predictive Biomarker (PRD): RHOJ mRNA
Genes: RHOJ; ARHJ; RASL7B; RHOI; TCL
Study 33295133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33295133 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35854762 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35854762 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 35854762 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33960725 — Predictive Biomarker (PRD): GPR84 mRNA
Genes: GPR84; EX33
Study 32386000 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 32386000 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 32386000 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32386000 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32169689 — Predictive Biomarker (PRD): ANTXR1 mRNA
Genes: ANTXR1; ATR; TEM8
Study 34848313 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 35666889 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 35666889 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 34895700 — Predictive Biomarker (PRD): REL mRNA
Genes: REL
Study 34895700 — Predictive Biomarker (PRD): Hormone receptor