TrialPanorama/TrialPanorama-database huggingface dataset:
Study 34111674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34111674 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34111674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32762012 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 35893925 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35893925 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 34934115 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 35395220 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 32233149 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 35899772 — Surrogate Endpoint (SUR): Blood pressure
Study 32697766 — Predictive Biomarker (PRD): BMPR1B mRNA
Genes: BMPR1B
Study 32697766 — Predictive Biomarker (PRD): IFITM3 mRNA
Genes: IFITM3
Study 32697766 — Predictive Biomarker (PRD): NLRC5 mRNA
Genes: NLRC5; NOD27; NOD4
Study 32697766 — Predictive Biomarker (PRD): SERINC2 mRNA
Genes: SERINC2; TDE2L; FKSG84; UNQ263/PRO300
Study 32697766 — Predictive Biomarker (PRD): CHST12 mRNA
Genes: CHST12; UNQ500/PRO1017
Study 32697766 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 32697766 — Predictive Biomarker (PRD): MARCKSL1 mRNA
Genes: MARCKSL1; MLP; MRP
Study 33336223 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 35998278 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 34117756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36288885 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 36288885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36288885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35605475 — Surrogate Endpoint (SUR): Blood pressure
Study 32871585 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study 32048083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36409665 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 36409665 — Safety Biomarker (SAF): BDNF
Study 34077643 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 35546633 — Safety Biomarker (SAF): DRD2
Study 35972592 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 34674222 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 35428210 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 35428210 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 34992358 — Surrogate Endpoint (SUR): Blood pressure
Study 32739411 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 35014928 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 35014928 — Predictive Biomarker (PRD): BIRC3 mRNA
Genes: BIRC3; API2; MIHC; RNF49
Study 35014928 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 35922216 — Surrogate Endpoint (SUR): Blood pressure
Study 35584353 — Surrogate Endpoint (SUR): Blood pressure
Study 34462864 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33228511 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 33228511 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 33228511 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34696674 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 34696674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34696674 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 34696674 — Surrogate Endpoint (SUR): Sperm parameters
Study 34696674 — Safety Biomarker (SAF): Reactive oxygen species
Study 34696674 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 32166681 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32166681 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 32649637 — Surrogate Endpoint (SUR): Blood pressure
Study 36054266 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 32910094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32910094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35852527 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33755917 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32875512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32355161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 34207545 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34207545 — Safety Biomarker (SAF): BDNF
Study 33744781 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 36223848 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 33481115 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 33755884 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 36037303 — Predictive Biomarker (PRD): SLC47A2 mRNA
Genes: SLC47A2; MATE2
Study 32473596 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 34195468 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 35495881 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35551646 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 34126996 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 34126996 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 34593232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32475085 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32475085 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 36514747 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34717532 — Surrogate Endpoint (SUR): Blood pressure
Study 33478173 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 34491227 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 35872982 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 32944404 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35171814 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 36063830 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 36063830 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 36063830 — Surrogate Endpoint (SUR): Serum testosterone
Study 34174097 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33636147 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 32124531 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 32124531 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 33140125 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 32061506 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 32469393 — Surrogate Endpoint (SUR): Blood pressure
Study 33381933 — Surrogate Endpoint (SUR): Serum creatinine
Study 33381933 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 36238498 — Surrogate Endpoint (SUR): Blood pressure
Study 35007358 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35007358 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35007358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32667903 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 33185002 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 37019385 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 32410694 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 32144909 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 32144909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32144909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32144909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32559817 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 35674759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35674759 — Surrogate Endpoint (SUR): Blood pressure
Study 35140061 — Surrogate Endpoint (SUR): Blood pressure
Study 33047696 — Surrogate Endpoint (SUR): Bacterial count
Study 34183490 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 32038628 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 32038628 — Predictive Biomarker (PRD): KLRC1 mRNA
Genes: KLRC1; NKG2A
Study 35420272 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32991794 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32991794 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 34578925 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 33981951 — Predictive Biomarker (PRD): Hormone receptor
Study 35178112 — Predictive Biomarker (PRD): LRIT1 mRNA
Genes: LRIT1; LRRC21; PAL
Study 35178112 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 32790196 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 32790196 — Surrogate Endpoint (SUR): Bone mineral density
Study 36323490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 36323490 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 35756957 — Surrogate Endpoint (SUR): Probing pocket depth
Study 34619639 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 35969429 — Surrogate Endpoint (SUR): Blood pressure
Study 35969429 — Surrogate Endpoint (SUR): Serum creatinine
Study 35969429 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 35969429 — Surrogate Endpoint (SUR): Serum uric acid
Study 33318635 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 32438531 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 36195542 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 34964849 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33440997 — Predictive Biomarker (PRD): ACSM3 mRNA
Genes: ACSM3; SAH
Study 33960689 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 33960689 — Predictive Biomarker (PRD): IL5RA mRNA
Genes: IL5RA; IL5R
Study 33960689 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 32777737 — Surrogate Endpoint (SUR): Forced vital capacity
Study 34563120 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 36044317 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 36044317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34597975 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 33765717 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 35794462 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 35427629 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 35427629 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 33066859 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 35534883 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 35534883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35534883 — Safety Biomarker (SAF): Interleukin 1
Study 35534883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32162501 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35510542 — Surrogate Endpoint (SUR): Blood pressure
Study 34666693 — Surrogate Endpoint (SUR): Blood pressure
Study 33546739 — Predictive Biomarker (PRD): AAK1 mRNA
Genes: AAK1; KIAA1048
Study 33546739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33546739 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 33546739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33765549 — Surrogate Endpoint (SUR): Blood pressure
Study 32043426 — Safety Biomarker (SAF): Hyaluronic acid
Study 35698094 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 36137629 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 36137629 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 93045359 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 93045359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32046747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34197227 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 34197227 — Surrogate Endpoint (SUR): Blood pressure
Study 33021477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34374108 — Surrogate Endpoint (SUR): Sperm parameters
Study 32165813 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32165813 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 32880214 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 34444779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34444779 — Surrogate Endpoint (SUR): Blood pressure
Study 34424347 — Predictive Biomarker (PRD): SLC11A1 mRNA
Genes: SLC11A1; LSH; NRAMP; NRAMP1
Study 34632925 — Predictive Biomarker (PRD): GUCY2C mRNA
Genes: GUCY2C; GUC2C; STAR
Study 33798297 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 34155411 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 32151562 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 32899001 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33092501 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 35184572 — Surrogate Endpoint (SUR): Blood pressure
Study 35184572 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 33096120 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 33096120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33096120 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 34582657 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 33883008 — Surrogate Endpoint (SUR): Blood pressure
Study 32598663 — Surrogate Endpoint (SUR): Blood pressure
Study 34174217 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 33658990 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 33658990 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33658990 — Safety Biomarker (SAF): Th2 cell
Study 33111359 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 32940689 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32940689 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 32940689 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 32940689 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 35658926 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 34913959 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35982468 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 35855512 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 35594703 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 33541495 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 33541495 — Monitoring Biomarker (MOI): Procalcitonin
Study 33541495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32337693 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 34397819 — Safety Biomarker (SAF): Interleukin 1
Study 36026657 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 36026657 — Surrogate Endpoint (SUR): Blood pressure
Study 35114057 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 35668567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35668567 — Monitoring Biomarker (MOI): Procalcitonin
Study 35668567 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 33992566 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34627611 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 32174632 — Surrogate Endpoint (SUR): Blood pressure
Study 35508656 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 35508656 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 33057705 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 33057705 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 35392963 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 33860116 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 33860116 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 36217872 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32703194 — Surrogate Endpoint (SUR): Blood pressure
Study 35384021 — Predictive Biomarker (PRD): CROT mRNA
Genes: CROT; COT
Study 32078787 — Surrogate Endpoint (SUR): Blood pressure
Study 32078787 — Safety Biomarker (SAF): Reactive oxygen species
Study 35462371 — Surrogate Endpoint (SUR): Serum potassium
Study 33888245 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33888245 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32571429 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33055456 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32643886 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 32487567 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33010112 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35263862 — Surrogate Endpoint (SUR): Blood pressure
Study 33536156 — Surrogate Endpoint (SUR): Blood pressure
Study 35090987 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 34369693 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34369693 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35472660 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 35399847 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 35988587 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 32199016 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32199016 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32199016 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 34187478 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 34187478 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 34187478 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 34187478 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 34187478 — Surrogate Endpoint (SUR): Serum calcium
Study 33191629 — Surrogate Endpoint (SUR): Blood pressure
Study 33676197 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study 33154508 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 35313167 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32859662 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 32859662 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 33474583 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 32346686 — Surrogate Endpoint (SUR): Bone mineral density
Study 33685474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33685474 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 33711941 — Surrogate Endpoint (SUR): Blood pressure
Study 35768902 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study 33359367 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 33359367 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 33359367 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF