TrialPanorama/TrialPanorama-database huggingface dataset:
Study 33593885 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 33593885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33593885 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34217593 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32538882 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 34000004 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 34535086 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 35820575 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 33826080 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 35998969 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 32445952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32534646 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 36334128 — Surrogate Endpoint (SUR): Blood pressure
Study 32543021 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 32543021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32543021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34935709 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 32433277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32433277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 36000934 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 33842907 — Safety Biomarker (SAF): Reactive oxygen species
Study 33842907 — Surrogate Endpoint (SUR): Bone mineral density
Study 33842907 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33842907 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33842907 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 36429439 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 32266197 — Surrogate Endpoint (SUR): Blood pressure
Study 34470478 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32851421 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 36297081 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 35180478 — Surrogate Endpoint (SUR): Blood pressure
Study 33788483 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 35438754 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study 32040462 — Safety Biomarker (SAF): Hyaluronic acid
Study 33734000 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 35401766 — Surrogate Endpoint (SUR): Bone mineral density
Study 35401766 — Surrogate Endpoint (SUR): Blood pressure
Study 32675474 — Surrogate Endpoint (SUR): Blood pressure
Study 37721420 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 37721420 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 37721420 — Surrogate Endpoint (SUR): Blood pressure
Study 36197253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35879693 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34236004 — Surrogate Endpoint (SUR): Blood pressure
Study 34013650 — Surrogate Endpoint (SUR): Probing pocket depth
Study 34779349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32023617 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 35570153 — Predictive Biomarker (PRD): BLK mRNA
Genes: BLK
Study 32841462 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 36035299 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 36035299 — Predictive Biomarker (PRD): HECW2 mRNA
Genes: HECW2; KIAA1301; NEDL2
Study 36035299 — Predictive Biomarker (PRD): TRIM66 mRNA
Genes: TRIM66; C11orf29; KIAA0298
Study 36035299 — Predictive Biomarker (PRD): MCTP2 mRNA
Genes: MCTP2
Study 33025656 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35610702 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 36288651 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 616651636 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 36111910 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 33039447 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 34223660 — Surrogate Endpoint (SUR): Blood pressure
Study 32581367 — Predictive Biomarker (PRD): Microsatellite instability
Study 33399006 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 32893710 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35578445 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 32694366 — Surrogate Endpoint (SUR): Bone mineral density
Study 32648392 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 32881761 — Surrogate Endpoint (SUR): Blood pressure
Study 33035687 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 33046514 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 32443343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32443343 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 32443343 — Surrogate Endpoint (SUR): Serum creatinine
Study 33662489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 34740538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 34740538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34740538 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 34750197 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 32818963 — Predictive Biomarker (PRD): CYP51A1 mRNA
Genes: CYP51A1; CYP51
Study 35236423 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 34243767 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 35978368 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 35978368 — Surrogate Endpoint (SUR): Blood pressure
Study 35536061 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 34337507 — Safety Biomarker (SAF): Hyaluronic acid
Study 35366328 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 35978946 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 32347005 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32347005 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33627186 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33861459 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 33861459 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 33861459 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 33861459 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33861657 — Safety Biomarker (SAF): Reactive oxygen species
Study 34180719 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 34180719 — Predictive Biomarker (PRD): FGF7 mRNA
Genes: FGF7; KGF
Study 34180719 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 34180719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34180719 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 34180719 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 34180719 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 34180719 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 32186161 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 34919104 — Surrogate Endpoint (SUR): Blood pressure
Study 35848865 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 35848865 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 35848865 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 32842783 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 33396972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33396972 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 33980057 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 32829666 — Surrogate Endpoint (SUR): Blood pressure
Study 35268025 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 35268025 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 33594986 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 34216524 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 34216524 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 34216524 — Surrogate Endpoint (SUR): Blood pressure
Study 36818484 — Surrogate Endpoint (SUR): Blood pressure
Study 36245315 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 36245315 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 35175572 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 37740217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 37740217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35472775 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35472775 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33589450 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33589450 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 33228592 — Predictive Biomarker (PRD): GOT1 mRNA
Genes: GOT1
Study 33228592 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 33228592 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 33228592 — Predictive Biomarker (PRD): PFKM mRNA
Genes: PFKM; PFKX
Study 33228592 — Predictive Biomarker (PRD): IER3 mRNA
Genes: IER3; DIF2; IEX1; PRG1
Study 33228592 — Predictive Biomarker (PRD): PFKFB4 mRNA
Genes: PFKFB4
Study 32799933 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 33994406 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 35165099 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 33553040 — Surrogate Endpoint (SUR): Blood pressure
Study 32967500 — Predictive Biomarker (PRD): GPX3 mRNA
Genes: GPX3; GPXP
Study 35483677 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35483677 — Surrogate Endpoint (SUR): Blood pressure
Study 33653909 — Surrogate Endpoint (SUR): Blood pressure
Study 35818183 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 35818183 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 34910136 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 36263570 — Surrogate Endpoint (SUR): Forced vital capacity
Study 33795561 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 36207050 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 36207050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33797462 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 33465273 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 34532749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 34532749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 34532749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 32196856 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 32464878 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 33522342 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 33522342 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 33522342 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33522342 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 33737200 — Surrogate Endpoint (SUR): Blood pressure
Study 33737200 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 32214062 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 33609104 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 33609104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33609104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 33609104 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 33609104 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 32594774 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 35390172 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 35264154 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32817311 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 32964537 — Surrogate Endpoint (SUR): Serum creatinine
Study 33612630 — Surrogate Endpoint (SUR): Blood pressure
Study 32966845 — Surrogate Endpoint (SUR): Pathological complete response
Study 34048946 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 34048946 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 32909643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35952621 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 34560903 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 32975202 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 35771546 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 35771546 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 35771546 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 35771546 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 32462542 — Surrogate Endpoint (SUR): Blood pressure
Study 35975564 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 33819509 — Predictive Biomarker (PRD): AIRE mRNA
Genes: AIRE; APECED
Study 32120316 — Surrogate Endpoint (SUR): Blood pressure
Study 32120316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35090399 — Surrogate Endpoint (SUR): Blood pressure
Study 36347569 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 36347569 — Pharmacodynamic Biomarker (PDY): GATA-type zinc finger protein 1
Genes: ZGLP1; GLP1
Study 35507334 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 34626008 — Predictive Biomarker (PRD): FECH mRNA
Genes: FECH
Study 34626008 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 33264662 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 33431819 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 33754924 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 33875324 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 33875324 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 33875324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 33875324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 33875324 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 33875324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35209942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 35209942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 35209942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 35209942 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 34863145 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 32000590 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 32004908 — Predictive Biomarker (PRD): EPCAM mRNA
Genes: EPCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1
Study 32005002 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 32005181 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 32005181 — Predictive Biomarker (PRD): Hormone receptor
Study 32006647 — Surrogate Endpoint (SUR): Blood pressure
Study 32007426 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 32007598 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 32008915 — Surrogate Endpoint (SUR): Blood pressure
Study 32009165 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 32009824 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 32010577 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 32010577 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 32010577 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 32010719 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 32010719 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 32012114 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32012116 — Surrogate Endpoint (SUR): Blood pressure
Study 32012159 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 32012214 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32012230 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 32012230 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 32012763 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 32013314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32013314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 32014432 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 32015566 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 32015566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 32016415 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 32016427 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 32016676 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 32017044 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 32017652 — Monitoring Biomarker (MOI): Circulating tumor HPV DNA
Study 32019278 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 32019278 — Surrogate Endpoint (SUR): Pathological complete response
Study 32019538 — Predictive Biomarker (PRD): TGFB2 mRNA
Genes: TGFB2
Study 32019538 — Predictive Biomarker (PRD): TGFBR1 mRNA
Genes: TGFBR1; ALK5; SKR4
Study 32019550 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 32019550 — Surrogate Endpoint (SUR): Blood pressure
Study 32020437 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 32020437 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 32020437 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 32021227 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 32023374 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 32023374 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56