TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04949399

Adverse event: Ophthalmic vascular thrombosis
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 209 at risk

Adverse event: Thyroid cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 209 at risk

Adverse event: Subarachnoid haemorrhage
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 209 at risk

Adverse event: Injection site bruising
Serious: no
Organ System: General disorders
Frequency: 5 affected / 209 at risk

Adverse event: COVID-19
Serious: no
Organ System: Infections and infestations
Frequency: 6 affected / 209 at risk

Adverse event: Appendicitis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 199 at risk

Adverse event: Cellulitis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 199 at risk

Adverse event: Injection site bruising
Serious: no
Organ System: General disorders
Frequency: 2 affected / 199 at risk

Adverse event: COVID-19
Serious: no
Organ System: Infections and infestations
Frequency: 9 affected / 199 at risk
Study: NCT04950998

Adverse event: Skin irritation from tape
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Participant reported skin irritation from the Tegederm tape used to adhere the activity monitor to the thigh.
Frequency: 1 affected / 15 at risk
Study: NCT04951076

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 18 affected / 105 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 13 affected / 105 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 6 affected / 105 at risk

Adverse event: Eleveted Liver Enzymes
Serious: no
Organ System: Investigations
Frequency: 14 affected / 105 at risk

Adverse event: Cholelithiasis
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 104 at risk

Adverse event: Chronic obstructive pulmonary disease
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 104 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 13 affected / 104 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 8 affected / 104 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 8 affected / 104 at risk

Adverse event: Eleveted Liver Enzymes
Serious: no
Organ System: Investigations
Frequency: 2 affected / 104 at risk
Study: NCT04951492

Adverse event: Pulmonary embolism
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 2 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 2 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 2 affected / 2 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 2 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 2 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 2 at risk

Adverse event: Myalgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 2 at risk

Adverse event: Bone pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 2 at risk

Adverse event: Left Forearm Tear
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 2 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 2 at risk

Adverse event: Dysgeusia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 2 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 2 at risk

Adverse event: White blood cell count decreased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 2 at risk

Adverse event: Neutrophil count decreased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 2 at risk

Adverse event: Supraventricular tachycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 2 at risk

Adverse event: Lymphocyte count decreased
Serious: no
Organ System: Investigations
Frequency: 2 affected / 2 at risk
Study: NCT04952389

Adverse event: Hyperglycaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 15 at risk

Adverse event: Brain fog
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 15 at risk
Study: NCT04952701

Adverse event: Light Sensitivity
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 63 at risk

Adverse event: Eye Irritation and Discomfort
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 63 at risk
Study: NCT04952909

Adverse event: All-cause stroke
Serious: yes
Organ System: Nervous system disorders
Notes: Per VARC-3
Frequency: 1 affected / 60 at risk

Adverse event: Coronary obstruction
Serious: yes
Organ System: Cardiac disorders
Notes: Per VARC-3
Frequency: 3 affected / 60 at risk

Adverse event: Myocardial Infarction with new evidence of coronary artery obstruction requiring intervention
Serious: yes
Organ System: Cardiac disorders
Notes: Per VARC-3
Frequency: 2 affected / 60 at risk

Adverse event: Cardiac tamponade
Serious: yes
Organ System: Cardiac disorders
Notes: Per VARC-3
Frequency: 1 affected / 60 at risk

Adverse event: Acute kidney injury stage 3-4
Serious: yes
Organ System: Renal and urinary disorders
Notes: Per VARC-3
Frequency: 2 affected / 60 at risk

Adverse event: Permanent pacemaker
Serious: yes
Organ System: Cardiac disorders
Frequency: 6 affected / 60 at risk

Adverse event: Left Bundle Branch Block (LBBB)
Serious: no
Organ System: Cardiac disorders
Frequency: 5 affected / 60 at risk
Study: NCT04953728

Adverse event: Haematochezia
Serious: no
Organ System: Gastrointestinal disorders
Notes: Noticed upon removal of balloon after PC6-100Hz stimulation.
Frequency: 1 affected / 20 at risk

Adverse event: Haematochezia
Serious: no
Organ System: Gastrointestinal disorders
Notes: Noticed 7 days after the previous study visit where sham stimulation was administered.
Frequency: 1 affected / 22 at risk

Adverse event: Eructation
Serious: no
Organ System: Gastrointestinal disorders
Notes: belching occurred after completion of the first distension and prior to sham stimulation
Frequency: 1 affected / 22 at risk
Study: NCT04955639

Adverse event: GI upset due to NRT lozenge or gum use
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 94 at risk

Adverse event: Skin irritation due to NRT patch use
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 7 affected / 94 at risk

Adverse event: Heartburn due to NRT lozenge or gum use
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 94 at risk

Adverse event: Sleep issues - wild dreams, insomnia
Serious: no
Organ System: General disorders
Frequency: 3 affected / 94 at risk

Adverse event: Headache due to NRT use
Serious: no
Organ System: General disorders
Frequency: 1 affected / 94 at risk

Adverse event: Jittery, racing heart, or lightheaded feeling due to NRT use
Serious: no
Organ System: General disorders
Frequency: 1 affected / 94 at risk

Adverse event: Mouth irritation or sore throat due to NRT lozenge or gum use
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 94 at risk

Adverse event: GI upset due to NRT lozenge or gum use
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 6 affected / 94 at risk

Adverse event: Skin irritation due to NRT patch use
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 7 affected / 94 at risk

Adverse event: Sleep issues - wild dreams, insomnia
Serious: no
Organ System: General disorders
Frequency: 3 affected / 94 at risk

Adverse event: Headache due to NRT use
Serious: no
Organ System: General disorders
Frequency: 1 affected / 94 at risk

Adverse event: Hiccups due to NRT lozenge or gum use
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 94 at risk

Adverse event: Jittery, racing heart, or lightheaded feeling due to NRT use
Serious: no
Organ System: General disorders
Frequency: 2 affected / 94 at risk

Adverse event: Mouth irritation or sore throat due to NRT lozenge or gum use
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 94 at risk
Study: NCT04955717

Adverse event: Abortion spontaneous
Serious: yes
Organ System: Pregnancy, puerperium and perinatal conditions
Notes: Defined as pregnancy loss before the 20th week of gestation wa identified through self-report by the participants, and through medical record abstraction.
Frequency: 11 affected / 251 at risk

Adverse event: Stillbirth
Serious: yes
Organ System: Pregnancy, puerperium and perinatal conditions
Notes: Defined as fetal death at or after 20 weeks gestation and prior to delivery, was identified through self-report by the participants, and medical record abstraction.
Frequency: 5 affected / 251 at risk

Adverse event: Abortion spontaneous
Serious: yes
Organ System: Pregnancy, puerperium and perinatal conditions
Notes: Defined as pregnancy loss before the 20th week of gestation wa identified through self-report by the participants, and through medical record abstraction.
Frequency: 9 affected / 249 at risk

Adverse event: Stillbirth
Serious: yes
Organ System: Pregnancy, puerperium and perinatal conditions
Notes: Defined as fetal death at or after 20 weeks gestation and prior to delivery, was identified through self-report by the participants, and medical record abstraction.
Frequency: 6 affected / 249 at risk
Study: NCT04958109

Adverse event: Skin and subcutaneous tissue disorders - Other, specify
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: IV site reaction or bruise
Frequency: 4 affected / 9 at risk

Adverse event: Menstruation irregular
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 2 affected / 9 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 9 at risk

Adverse event: Infections and Infestations - Other, Specify
Serious: no
Organ System: Infections and infestations
Notes: Coronavirus disease infection 2019 No subject had the Infection during active study protocol
Frequency: 1 affected / 9 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 1 affected / 9 at risk

Adverse event: Breast pain
Serious: no
Organ System: Reproductive system and breast disorders
Notes: Subject reported typical breast pain associated with menstruation, while menstruating
Frequency: 1 affected / 9 at risk

Adverse event: Skin and subcutaneous tissue disorders - Other, specify
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: IV site reaction or bruise
Frequency: 4 affected / 9 at risk

Adverse event: Dysmenorrhoea
Serious: no
Organ System: Reproductive system and breast disorders
Notes: Subject reported menstrual cramps while menstruating
Frequency: 1 affected / 9 at risk

Adverse event: Menstruation irregular
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 9 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 9 at risk

Adverse event: Infections and Infestations - Other, Specify
Serious: no
Organ System: Infections and infestations
Notes: Coronavirus disease infection 2019 No subject had the Infection during active study protocol
Frequency: 2 affected / 9 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 1 affected / 9 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 9 at risk
Study: NCT04958200

Adverse event: hospital visit for uncontrolled diabetes
Serious: no
Organ System: Metabolism and nutrition disorders
Notes: diabetes regulated after visit to hospital
Frequency: 1 affected / 24 at risk

Adverse event: Hospitalisation
Serious: yes
Organ System: Injury, poisoning and procedural complications
Notes: participant hospitalized for car accident....broken bones in feet...not study related
Frequency: 1 affected / 24 at risk
Study: NCT04962009

Adverse event: Foreign Body sensation, single/mild
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 12 at risk

Adverse event: retinal migraine OS
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 12 at risk
Study: NCT04962230

Adverse event: Vessel puncture site haematoma
Serious: no
Organ System: General disorders
Frequency: 1 affected / 12 at risk

Adverse event: Dysgeusia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 12 at risk

Adverse event: Sciatica
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 12 at risk

Adverse event: Polyuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 12 at risk

Adverse event: Excessive cerumen production
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 12 at risk

Adverse event: Inappropriate antidiuretic hormone secretion
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 12 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 12 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 12 at risk

Adverse event: Vessel puncture site haematoma
Serious: no
Organ System: General disorders
Frequency: 1 affected / 12 at risk

Adverse event: COVID-19
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 12 at risk

Adverse event: Transaminases increased
Serious: no
Organ System: Investigations
Frequency: 5 affected / 12 at risk

Adverse event: Altered pitch perception
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 12 at risk

Adverse event: Dysgeusia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 12 at risk

Adverse event: Poor quality sleep
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 12 at risk

Adverse event: Sinus congestion
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 12 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 12 at risk

Adverse event: Dermatitis contact
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 12 at risk
Study: NCT04962503

Adverse event: Haemorrhagic transformation stroke
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 6 at risk

Adverse event: Cerebrovascular accident
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 6 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 6 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 6 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 6 at risk

Adverse event: Troponin increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 6 at risk

Adverse event: Hypervolaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 6 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 6 at risk

Adverse event: Haemorrhagic transformation stroke
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 6 at risk

Adverse event: Delirium
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 6 at risk
Study: NCT04963062

Adverse event: Obstructing fragments required surgical treatment
Serious: no
Organ System: Renal and urinary disorders
Notes: Patients had obstructing fragments which required unplanned surgery.
Frequency: 1 affected / 52 at risk

Adverse event: Obstructing fragments passed
Serious: no
Organ System: Renal and urinary disorders
Notes: Obstructing fragments passed successfully
Frequency: 1 affected / 52 at risk

Adverse event: ER visit and discharge
Serious: no
Organ System: Renal and urinary disorders
Notes: Patient ER visit within the follow up period
Frequency: 1 affected / 52 at risk

Adverse event: UTI treated with outpatient antibiotics
Serious: no
Organ System: Renal and urinary disorders
Frequency: 2 affected / 52 at risk

Adverse event: Obstructing fragments required surgical treatment
Serious: no
Organ System: Renal and urinary disorders
Notes: Patients had obstructing fragments which required unplanned surgery.
Frequency: 2 affected / 56 at risk

Adverse event: ER visit and discharge
Serious: no
Organ System: Renal and urinary disorders
Notes: Patient ER visit within the follow up period
Frequency: 3 affected / 56 at risk

Adverse event: UTI treated with outpatient antibiotics
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 56 at risk
Study: NCT04963179

Adverse event: Uterine perforation
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 77 at risk

Adverse event: Liver function test abnormal
Serious: no
Organ System: Investigations
Frequency: 1 affected / 77 at risk

Adverse event: Urethral pain
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 77 at risk

Adverse event: Vulvovaginal pruritus
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 77 at risk

Adverse event: Cervix disorder
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 77 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 77 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 86 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 86 at risk

Adverse event: Neuralgia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 86 at risk
Study: NCT04964128

Adverse event: Hypoglycaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 18 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 18 at risk

Adverse event: Viral infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 18 at risk

Adverse event: Epididymitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 18 at risk
Study: NCT04964453

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 8 at risk

Adverse event: Orthostatic intolerance
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 8 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 6 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 6 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 6 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 6 at risk

Adverse event: Blood potassium decreased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk
Study: NCT04964960

Adverse event: Atrial fibrillation
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 2 at risk

Adverse event: Cardiac disorders - Other
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 2 at risk

Adverse event: Palpitations
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 2 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 2 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 2 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 2 affected / 2 at risk

Adverse event: Influenza like illness
Serious: no
Organ System: General disorders
Frequency: 1 affected / 2 at risk

Adverse event: Other
Serious: no
Organ System: General disorders
Frequency: 1 affected / 2 at risk

Adverse event: Sinusitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 2 at risk

Adverse event: Tooth infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 2 at risk

Adverse event: Alanine aminotransferase increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 2 at risk

Adverse event: Blood alkaline phosphatase increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 2 at risk

Adverse event: Aspartate aminotransferase increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 2 at risk

Adverse event: Blood creatinine increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 2 at risk

Adverse event: Lymphocyte count decreased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 2 at risk

Adverse event: Weight increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 2 at risk

Adverse event: Hypokalaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 2 at risk

Adverse event: Pain in extremity
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 2 at risk

Adverse event: Peripheral sensory neuropathy
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 2 at risk

Adverse event: Muscle spasticity
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 2 at risk