TrialPanorama/TrialPanorama-database huggingface dataset:
Study: 32690739

Adverse event: death

Adverse event: discharge

Adverse event: respiratory failure

Adverse event: endotracheal intubation

Adverse event: respiratory failure

Adverse event: endotracheal intubation

Adverse event: mechanical ventilation
Study: 34062418

Adverse event: fasting
Study: 35752785

Adverse event: metastasis
Study: 36067241

Adverse event: depression
Study: 32027167

Adverse event: fasting

Adverse event: fasting
Study: 33091038

Adverse event: muscle mass

Adverse event: mass

Adverse event: muscle mass

Adverse event: mass
Study: 35076629

Adverse event: metamorphopsia
Study: 33091038

Adverse event: muscle mass

Adverse event: mass
Study: 35443809

Adverse event: discharge
Study: 32236553

Adverse event: pain

Adverse event: pain
Study: 33998255

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction
Study: 32445576

Adverse event: stenosis

Adverse event: restenosis

Adverse event: stenosis

Adverse event: restenosis

Adverse event: restenosis

Adverse event: restenosis
Study: 32910353

Adverse event: hiv test

Adverse event: hiv test
Study: 36196872

Adverse event: stress

Adverse event: anxiety
Study: 36191863

Adverse event: fear

Adverse event: fear

Adverse event: fear

Adverse event: fear
Study: 32273162

Adverse event: live birth

Adverse event: live birth
Study: 35168962

Adverse event: haemostasis
Study: 32224326

Adverse event: pain
Study: 33967755

Adverse event: death

Adverse event: death

Adverse event: death

Adverse event: death
Study: 33476880

Adverse event: disability

Adverse event: disability

Adverse event: disability
Study: 35620899

Adverse event: obstruction
Study: 32514702

Adverse event: pain

Adverse event: pain
Study: 33421446

Adverse event: infection

Adverse event: culture
Study: 33882918

Adverse event: laparoscopy

Adverse event: laparotomy

Adverse event: laparoscopy

Adverse event: laparotomy

Adverse event: pain

Adverse event: laparoscopy

Adverse event: laparotomy

Adverse event: cyst

Adverse event: laparoscopy

Adverse event: cyst rupture
Study: 33746207

Adverse event: dry eye

Adverse event: dry eye
Study: 32833890

Adverse event: fatigue
Study: 32973143

Adverse event: emotional distress

Adverse event: emotional distress
Study: 34656202

Adverse event: pain

Adverse event: anxiety

Adverse event: pain
Study: 36510286

Adverse event: weight

Adverse event: pregnancy

Adverse event: childhood
Study: 35775843

Adverse event: anastomotic leak

Adverse event: surgery

Adverse event: anastomotic leak

Adverse event: surgery
Study: 32111316

Adverse event: lipase

Adverse event: weight

Adverse event: lipase

Adverse event: carnitine
Study: 35679195

Adverse event: manipulation
Study: 34446499

Adverse event: hydrocephalus
Study: 34281376

Adverse event: nih stroke scale
Study: 32349223

Adverse event: heart rate

Adverse event: weight

Adverse event: body mass index

Adverse event: mass

Adverse event: low density lipoprotein
Study: 33809544

Adverse event: insomnia
Study: 35062997

Adverse event: depressed mood

Adverse event: pain

Adverse event: surgery

Adverse event: anxiety
Study: 33386796

Adverse event: ejection fraction

Adverse event: troponin t

Adverse event: troponin
Study: 35062997

Adverse event: pain
Study: 33386796

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: hypotension
Study: 33769598

Adverse event: illness

Adverse event: critical illness

Adverse event: illness

Adverse event: critical illness

Adverse event: weight
Study: 36127117

Adverse event: pain

Adverse event: fatigue

Adverse event: inflammation
Study: 33217874

Adverse event: anxiety

Adverse event: anxiety
Study: 33561824

Adverse event: cortisol increased

Adverse event: cortisol increased
Study: 33430613

Adverse event: infection
Study: 33725907

Adverse event: biopsy

Adverse event: biopsy
Study: 35213714

Adverse event: hyperphagia

Adverse event: obesity

Adverse event: adverse event
Study: 32320767

Adverse event: psoriasis
Study: 32806954

Adverse event: headache

Adverse event: headache

Adverse event: headache

Adverse event: headache
Study: 33997968

Adverse event: foster care

Adverse event: interactions

Adverse event: interactions
Study: 34244248

Adverse event: weight
Study: 32487336

Adverse event: tonsillitis

Adverse event: tonsillitis

Adverse event: tonsillitis
Study: 33997968

Adverse event: foster care

Adverse event: interactions
Study: 36167423

Adverse event: heart rate

Adverse event: thirst

Adverse event: discomfort
Study: 36244779

Adverse event: depression

Adverse event: respiratory depression
Study: 35183923

Adverse event: swelling

Adverse event: swelling
Study: 34567596

Adverse event: disability

Adverse event: osteoarthritis
Study: 34936044

Adverse event: circumcision
Study: 36633795

Adverse event: acne

Adverse event: scar
Study: 33497585

Adverse event: surgery

Adverse event: surgery
Study: 32464321

Adverse event: death

Adverse event: death
Study: 35710102

Adverse event: oxygen consumption

Adverse event: oxygen consumption increased
Study: 33360089

Adverse event: fatigue
Study: 35710102

Adverse event: oxygen consumption

Adverse event: oxygen consumption

Adverse event: oxygen consumption increased
Study: 36432444

Adverse event: restlessness
Study: 33127493

Adverse event: surgery
Study: 36443491

Adverse event: discharge
Study: 36102482

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: hernia
Study: 33712080

Adverse event: pain

Adverse event: pain
Study: 33331495

Adverse event: insomnia

Adverse event: anxiety

Adverse event: insomnia

Adverse event: anxiety
Study: 34872441

Adverse event: cytogenetic response
Study: 33301246

Adverse event: injection

Adverse event: pain

Adverse event: fatigue

Adverse event: headache
Study: 34338369

Adverse event: surgery

Adverse event: surgery
Study: 32852904

Adverse event: discharge
Study: 34910089

Adverse event: weight

Adverse event: weight

Adverse event: pregnancy

Adverse event: pregnancy

Adverse event: delivery

Adverse event: delivery
Study: 32852904

Adverse event: pain

Adverse event: discharge

Adverse event: discharge

Adverse event: dizziness

Adverse event: hypotension

Adverse event: urinary retention

Adverse event: tension
Study: 33980995

Adverse event: surgery

Adverse event: vitamin d

Adverse event: vitamin d deficiency

Adverse event: surgery

Adverse event: vitamin d

Adverse event: vitamin d deficiency
Study: 32378654

Adverse event: weight

Adverse event: weight
Study: 35905197

Adverse event: pain

Adverse event: necrosis
Study: 34243719

Adverse event: surgery

Adverse event: pain
Study: 33779480

Adverse event: anxiety
Study: 32923417

Adverse event: blood pressure decreased

Adverse event: body mass index

Adverse event: mass

Adverse event: blood pressure increased
Study: 35568489

Adverse event: suicidal ideation
Study: 32330971

Adverse event: transfusion

Adverse event: infection

Adverse event: wound

Adverse event: wound infection
Study: 32623375

Adverse event: weight
Study: 35725632

Adverse event: pain

Adverse event: pain

Adverse event: infant

Adverse event: pain
Study: 35791269

Adverse event: discharge
Study: 35725632

Adverse event: infant

Adverse event: pain
Study: 35791269

Adverse event: discharge

Adverse event: discharge
Study: 32631820

Adverse event: infant

Adverse event: pregnancy
Study: 33950030

Adverse event: menopause
Study: 32811740

Adverse event: weight

Adverse event: fear
Study: 33836826

Adverse event: nasopharyngeal swab

Adverse event: viral load

Adverse event: cough

Adverse event: death

Adverse event: nasopharyngeal swab

Adverse event: viral load

Adverse event: cough

Adverse event: death
Study: 33635540

Adverse event: renal replacement therapy
Study: 33249482

Adverse event: norepinephrine

Adverse event: adhesion

Adverse event: vasodilatation

Adverse event: norepinephrine

Adverse event: adhesion

Adverse event: inflammation
Study: 35791906

Adverse event: alcohol use
Study: 33342719

Adverse event: viral load

Adverse event: viral load
Study: 35256599

Adverse event: weight
Study: 33342719

Adverse event: antiretroviral therapy
Study: 34879480

Adverse event: married

Adverse event: married
Study: 35197358

Adverse event: eczema

Adverse event: eczema
Study: 36029512

Adverse event: necrosis

Adverse event: inflammation

Adverse event: necrosis

Adverse event: inflammation
Study: 34239941

Adverse event: adenocarcinoma

Adverse event: lung adenocarcinoma

Adverse event: adenocarcinoma

Adverse event: lung adenocarcinoma
Study: 32851411

Adverse event: influenza
Study: 35159306

Adverse event: supraventricular extrasystoles

Adverse event: extrasystoles

Adverse event: supraventricular extrasystoles

Adverse event: extrasystoles

Adverse event: heart rate
Study: 35318529

Adverse event: surgery
Study: 33558351

Adverse event: psychotherapy
Study: 32121286

Adverse event: infant

Adverse event: infant
Study: 33045448

Adverse event: pregnancy
Study: 32686119

Adverse event: caregiver
Study: 36180155

Adverse event: pain

Adverse event: pain
Study: 36498075

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 32940695

Adverse event: eating disorder
Study: 32016585

Adverse event: coma scale

Adverse event: coma

Adverse event: discharge

Adverse event: mechanical ventilation

Adverse event: coma scale

Adverse event: coma

Adverse event: discharge

Adverse event: mechanical ventilation
Study: 35174636

Adverse event: fasting
Study: 34085796

Adverse event: surgery

Adverse event: surgery
Study: 34437978

Adverse event: aneurysm

Adverse event: aneurysm
Study: 36123051

Adverse event: visual analogue scale

Adverse event: visual analogue scale

Adverse event: wound

Adverse event: wound
Study: 34509670

Adverse event: pain

Adverse event: pain
Study: 33524549

Adverse event: pain
Study: 36414937

Adverse event: weight
Study: 35617820

Adverse event: fatigue

Adverse event: fatigue

Adverse event: fatigue

Adverse event: fatigue
Study: 32652012

Adverse event: vomiting
Study: 33159632

Adverse event: psychotherapy
Study: 32857955

Adverse event: depression

Adverse event: anxiety

Adverse event: anxiety symptoms
Study: 35578302

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 35253516

Adverse event: adverse event

Adverse event: adverse event

Adverse event: adverse event

Adverse event: adverse event
Study: 32066404

Adverse event: heart rate
Study: 34454653

Adverse event: death

Adverse event: death
Study: 33649451

Adverse event: dementia

Adverse event: dementia
Study: 32909511

Adverse event: nephropathy

Adverse event: nephropathy
Study: 36129693

Adverse event: microalbuminuria

Adverse event: microalbuminuria

Adverse event: death
Study: 32602273

Adverse event: glycated albumin

Adverse event: glycated albumin
Study: 35860451

Adverse event: dementia

Adverse event: dementia

Adverse event: dementia
Study: 32591869

Adverse event: pain

Adverse event: pain
Study: 32128907

Adverse event: pain

Adverse event: oral candidiasis
Study: 34716281

Adverse event: respiratory symptom

Adverse event: inflammation

Adverse event: infection
Study: 33956256

Adverse event: discomfort

Adverse event: foreign body

Adverse event: surgery
Study: 32421353

Adverse event: treatment failure

Adverse event: treatment failure
Study: 36084154

Adverse event: oxygenation index

Adverse event: atelectasis

Adverse event: atelectasis

Adverse event: surgery

Adverse event: atelectasis

Adverse event: surgery

Adverse event: atelectasis

Adverse event: atelectasis

Adverse event: extubation

Adverse event: atelectasis

Adverse event: extubation

Adverse event: oxygenation index
Study: 32014032

Adverse event: neurological examination

Adverse event: neurological examination

Adverse event: montreal cognitive assessment

Adverse event: montreal cognitive assessment
Study: 36054369

Adverse event: olfactory dysfunction

Adverse event: anosmia
Study: 34510966

Adverse event: pregnancy
Study: 33508918

Adverse event: surgery

Adverse event: nausea

Adverse event: fatigue

Adverse event: gastritis

Adverse event: pneumonia
Study: 34639109

Adverse event: injection

Adverse event: injection

Adverse event: injection

Adverse event: progesterone
Study: 616886751

Adverse event: pain

Adverse event: cancer pain

Adverse event: pain
Study: 32856146

Adverse event: infection

Adverse event: urinary tract infection

Adverse event: infection

Adverse event: urinary tract infection

Adverse event: glomerular filtration rate
Study: 35060868

Adverse event: stress
Study: 35813434

Adverse event: oxygen saturation

Adverse event: blood glucose

Adverse event: stroke volume

Adverse event: cardiac output

Adverse event: po2

Adverse event: carbon dioxide

Adverse event: pco2
Study: 33070176

Adverse event: culture

Adverse event: culture

Adverse event: liver injury

Adverse event: injury

Adverse event: acute kidney injury

Adverse event: injury
Study: 32795283

Adverse event: pain
Study: 35785423

Adverse event: pain
Study: 33434035

Adverse event: scab
Study: 33252568

Adverse event: keratometry
Study: 35147387

Adverse event: nephrectomy
Study: 32436455

Adverse event: death
Study: 35060222

Adverse event: fatigue
Study: 35060222

Adverse event: depression

Adverse event: fatigue
Study: 34370916

Adverse event: gingival bleeding

Adverse event: gingival bleeding
Study: 32682347

Adverse event: disability

Adverse event: insomnia
Study: 32144884

Adverse event: pain
Study: 35715184

Adverse event: live birth

Adverse event: live birth

Adverse event: endometriosis

Adverse event: delivery

Adverse event: hypertension

Adverse event: pregnancy

Adverse event: haemorrhage

Adverse event: endometriosis

Adverse event: delivery

Adverse event: hypertension

Adverse event: pregnancy

Adverse event: haemorrhage
Study: 37676213

Adverse event: transferrin
Study: 32548854

Adverse event: infusion

Adverse event: migraine
Study: 33692176

Adverse event: irritability

Adverse event: depression

Adverse event: anxiety

Adverse event: irritability
Study: 32444190

Adverse event: blood pressure diastolic

Adverse event: blood glucose

Adverse event: fasting
Study: 34610929

Adverse event: stress

Adverse event: stress
Study: 33004472

Adverse event: fasting

Adverse event: fasting

Adverse event: fasting
Study: 35143872

Adverse event: grip strength
Study: 34396584

Adverse event: injection

Adverse event: injection
Study: 36050587

Adverse event: depression

Adverse event: stress
Study: 32737435

Adverse event: infant
Study: 33455924

Adverse event: depression

Adverse event: depression

Adverse event: depression

Adverse event: depression

Adverse event: depression
Study: 33357217

Adverse event: embolism
Study: 34246993

Adverse event: death
Study: 32712569

Adverse event: alcohol use

Adverse event: alcohol use
Study: 35016497

Adverse event: extubation
Study: 32636043

Adverse event: grip strength
Study: 32861085

Adverse event: sleep disorder
Study: 33900249

Adverse event: crying

Adverse event: pain
Study: 32636043

Adverse event: fracture
Study: 32488902

Adverse event: pneumonia

Adverse event: pneumonia
Study: 33900249

Adverse event: crying

Adverse event: pain

Adverse event: pain
Study: 32636043

Adverse event: fracture

Adverse event: grip strength
Study: 32488902

Adverse event: osteoporosis

Adverse event: pneumonia
Study: 32078147

Adverse event: pain

Adverse event: pain
Study: 35941676

Adverse event: childhood
Study: 32087425

Adverse event: weight

Adverse event: weight

Adverse event: weight

Adverse event: weight
Study: 34984679

Adverse event: head and neck cancer

Adverse event: head and neck cancer
Study: 32647106

Adverse event: drainage

Adverse event: pain

Adverse event: back pain

Adverse event: drainage
Study: 35134897

Adverse event: death
Study: 32647106

Adverse event: pain

Adverse event: back pain
Study: 35137532

Adverse event: viral load
Study: 32821078

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 32444343

Adverse event: heart rate

Adverse event: heart rate

Adverse event: arterial stiffness
Study: 32507432

Adverse event: menopause
Study: 33994141

Adverse event: shock
Study: 35488222

Adverse event: depression

Adverse event: depression
Study: 34183431

Adverse event: ketoacidosis
Study: 34992123

Adverse event: ulcer

Adverse event: wound
Study: 33846037

Adverse event: colorectal cancer

Adverse event: colorectal cancer
Study: 35411785

Adverse event: myocardial infarction

Adverse event: infarction
Study: 34052007

Adverse event: cough

Adverse event: lymphopenia

Adverse event: cough

Adverse event: lymphopenia
Study: 35621233

Adverse event: discharge

Adverse event: discharge

Adverse event: acute kidney injury

Adverse event: injury
Study: 34262120

Adverse event: dizziness

Adverse event: vertigo
Study: 36243227

Adverse event: anxiety
Study: 33726983

Adverse event: anxiety
Study: 35990583

Adverse event: fatigue

Adverse event: anaemia

Adverse event: nausea

Adverse event: fatigue

Adverse event: nausea
Study: 34983471

Adverse event: pain

Adverse event: surgery

Adverse event: pain

Adverse event: surgery

Adverse event: surgery

Adverse event: surgery
Study: 34480134

Adverse event: hypertension
Study: 33316455

Adverse event: continuous glucose monitoring

Adverse event: continuous glucose monitoring

Adverse event: blood glucose
Study: 34508154

Adverse event: oxygen consumption

Adverse event: heart rate

Adverse event: stress

Adverse event: weight

Adverse event: heart rate
Study: 35658959

Adverse event: weight

Adverse event: waist circumference

Adverse event: weight

Adverse event: hunger

Adverse event: lipids

Adverse event: mass

Adverse event: waist circumference

Adverse event: hunger

Adverse event: mass
Study: 32238534

Adverse event: interactions

Adverse event: stress

Adverse event: anxiety

Adverse event: anxiety symptoms

Adverse event: anxiety

Adverse event: anxiety symptoms
Study: 34000940

Adverse event: visual analogue scale
Study: 34406839

Adverse event: fatigue

Adverse event: insomnia

Adverse event: fatigue

Adverse event: insomnia
Study: 33048789

Adverse event: hypertension

Adverse event: metabolic syndrome
Study: 34091568

Adverse event: discharge

Adverse event: discharge

Adverse event: injury
Study: 35589362

Adverse event: stress

Adverse event: depression

Adverse event: anxiety
Study: 36286314

Adverse event: pain

Adverse event: abdominal pain

Adverse event: pain

Adverse event: abdominal pain
Study: 33935219

Adverse event: fractures
Study: 35649597

Adverse event: dizziness

Adverse event: vomiting

Adverse event: obstruction

Adverse event: nausea

Adverse event: dizziness

Adverse event: vomiting

Adverse event: obstruction

Adverse event: nausea
Study: 32811575

Adverse event: depression
Study: 33618683

Adverse event: death

Adverse event: breast cancer
Study: 33367924

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 32195928

Adverse event: depression
Study: 33172509

Adverse event: weight

Adverse event: weight

Adverse event: waist circumference

Adverse event: waist circumference

Adverse event: insulin resistance

Adverse event: insulin resistance
Study: 35649228

Adverse event: chemotherapy
Study: 34544939

Adverse event: infection

Adverse event: infection

Adverse event: antifungal treatment

Adverse event: neutropenia

Adverse event: antifungal treatment

Adverse event: infection

Adverse event: infection

Adverse event: antifungal treatment

Adverse event: neutropenia

Adverse event: antifungal treatment
Study: 35945094

Adverse event: disability

Adverse event: migraine
Study: 35867804

Adverse event: cardiac index

Adverse event: infusion site pain

Adverse event: pain

Adverse event: vomiting

Adverse event: infusion

Adverse event: nausea
Study: 35381034

Adverse event: stress
Study: 32515840

Adverse event: drain removal

Adverse event: seroma
Study: 35762581

Adverse event: stenosis

Adverse event: arterial stenosis

Adverse event: stenosis

Adverse event: arterial stenosis

Adverse event: stenosis

Adverse event: arterial stenosis
Study: 34227951

Adverse event: discharge
Study: 34587328

Adverse event: infection
Study: 33172953

Adverse event: depression
Study: 35413573

Adverse event: neutropenia
Study: 33639478

Adverse event: elderly

Adverse event: elderly
Study: 36394533

Adverse event: visual analogue scale
Study: 32654539

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction
Study: 32973057

Adverse event: death

Adverse event: death
Study: 33546534

Adverse event: scar

Adverse event: scar
Study: 35658059

Adverse event: discomfort
Study: 34550034

Adverse event: deep vein thrombosis

Adverse event: thrombosis

Adverse event: embolism

Adverse event: pulmonary embolism

Adverse event: thrombin time

Adverse event: prothrombin time
Study: 35241779

Adverse event: anxiety
Study: 33285143

Adverse event: influenza

Adverse event: influenza

Adverse event: antiviral treatment

Adverse event: influenza

Adverse event: influenza
Study: 35897119

Adverse event: suicidal behaviour
Study: 35337672

Adverse event: surgery

Adverse event: chemotherapy

Adverse event: chemotherapy
Study: 35576873

Adverse event: inflammation

Adverse event: inflammation
Study: 32376505

Adverse event: weight
Study: 35172779

Adverse event: pain
Study: 35486948

Adverse event: antithrombin iii

Adverse event: protein c

Adverse event: protein s
Study: 34910297

Adverse event: weight

Adverse event: vomiting

Adverse event: insomnia

Adverse event: nausea

Adverse event: constipation

Adverse event: dizziness
Study: 34660195

Adverse event: fatigue
Study: 34061234

Adverse event: dyspareunia

Adverse event: dyspareunia

Adverse event: dyspareunia
Study: 33545954

Adverse event: tinnitus

Adverse event: disability

Adverse event: tinnitus

Adverse event: disability
Study: 34061234

Adverse event: dyspareunia

Adverse event: surgery

Adverse event: sexually active
Study: 36617611

Adverse event: obstruction

Adverse event: nasal obstruction

Adverse event: acupuncture
Study: 33199418

Adverse event: oxygen saturation

Adverse event: laryngoscopy

Adverse event: oxygen saturation

Adverse event: laryngoscopy

Adverse event: oxygen saturation

Adverse event: laryngoscopy
Study: 34506827

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: thrombosis
Study: 36289532

Adverse event: transplant
Study: 33449510

Adverse event: pain

Adverse event: anxiety

Adverse event: pain

Adverse event: anxiety

Adverse event: pain
Study: 36109354

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: vomiting

Adverse event: nausea
Study: 33725939

Adverse event: aneurysm

Adverse event: disability

Adverse event: aneurysm

Adverse event: disability
Study: 32612066

Adverse event: renin

Adverse event: renin
Study: 35301859

Adverse event: headache

Adverse event: headache

Adverse event: heart rate

Adverse event: headache

Adverse event: heart rate

Adverse event: headache
Study: 34362409

Adverse event: weight

Adverse event: body mass index

Adverse event: mass
Study: 32475446

Adverse event: weight
Study: 34362409

Adverse event: fasting
Study: 33372291

Adverse event: weight

Adverse event: overweight

Adverse event: respiratory distress

Adverse event: death

Adverse event: dysplasia

Adverse event: patent ductus arteriosus

Adverse event: bronchopulmonary dysplasia

Adverse event: retinopathy

Adverse event: retinopathy of prematurity

Adverse event: enterocolitis

Adverse event: intraventricular haemorrhage

Adverse event: mechanical ventilation

Adverse event: haemorrhage