Study: NCT04562779

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 1 affected / 14 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 1 affected / 14 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Gastrointestinal disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: nausea/vomiting
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 1 affected / 14 at risk

Adverse event: nausea/vomiting
Serious: no
Organ System: Gastrointestinal disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 4 affected / 14 at risk

Adverse event: Increased appetite
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 3 affected / 14 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 4 affected / 14 at risk

Adverse event: Palpitations
Serious: no
Organ System: Cardiac disorders
Notes: tolerable
Frequency: 1 affected / 14 at risk

Adverse event: Palpitations
Serious: no
Organ System: Cardiac disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: dizziness on standing
Serious: no
Organ System: Cardiac disorders
Notes: tolerable
Frequency: 2 affected / 14 at risk

Adverse event: dizziness on standing
Serious: no
Organ System: Cardiac disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: Chest pain
Serious: no
Organ System: Cardiac disorders
Notes: tolerable
Frequency: 2 affected / 14 at risk

Adverse event: Chest pain
Serious: no
Organ System: Cardiac disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: tolerable
Frequency: 1 affected / 14 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: distressing
Frequency: 2 affected / 14 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: tolerable
Frequency: 2 affected / 14 at risk

Adverse event: pain with breathing
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: tolerable
Frequency: 2 affected / 14 at risk

Adverse event: increased perspiration
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: tolerable
Frequency: 1 affected / 14 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: tolerable
Frequency: 1 affected / 14 at risk

Adverse event: Dry skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: tolerable
Frequency: 3 affected / 14 at risk

Adverse event: Dry skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Notes: tolerable
Frequency: 2 affected / 14 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: Tremor
Serious: no
Organ System: Nervous system disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: poor coordination
Serious: no
Organ System: Nervous system disorders
Notes: tolerable
Frequency: 2 affected / 14 at risk

Adverse event: poor coordination
Serious: no
Organ System: Nervous system disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: dizziness or lightheadedness
Serious: no
Organ System: Nervous system disorders
Notes: tolerable
Frequency: 3 affected / 14 at risk

Adverse event: numbness or tingling
Serious: no
Organ System: Nervous system disorders
Notes: tolerable
Frequency: 2 affected / 14 at risk

Adverse event: speech difficulty
Serious: no
Organ System: Nervous system disorders
Notes: tolerable
Frequency: 2 affected / 14 at risk

Adverse event: speech difficulty
Serious: no
Organ System: Nervous system disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: Vision blurred
Serious: no
Organ System: Eye disorders
Notes: tolerable
Frequency: 1 affected / 14 at risk

Adverse event: Vision blurred
Serious: no
Organ System: Eye disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: frequent urination
Serious: no
Organ System: Renal and urinary disorders
Notes: tolerable
Frequency: 1 affected / 14 at risk

Adverse event: decreased libido
Serious: no
Organ System: Reproductive system and breast disorders
Notes: tolerable
Frequency: 1 affected / 14 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 2 affected / 14 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: Abnormal dreams
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 3 affected / 14 at risk

Adverse event: Abnormal dreams
Serious: no
Organ System: Psychiatric disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 2 affected / 14 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Notes: distressing
Frequency: 4 affected / 14 at risk

Adverse event: Hallucination
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 1 affected / 14 at risk

Adverse event: Amnesia
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 2 affected / 14 at risk

Adverse event: Amnesia
Serious: no
Organ System: Psychiatric disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: Disturbance in attention
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 3 affected / 14 at risk

Adverse event: Disturbance in attention
Serious: no
Organ System: Psychiatric disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: fatigue or decreased energy
Serious: no
Organ System: General disorders
Notes: tolerable
Frequency: 4 affected / 14 at risk

Adverse event: fatigue or decreased energy
Serious: no
Organ System: Psychiatric disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: Restlessness
Serious: no
Organ System: General disorders
Notes: tolerable
Frequency: 4 affected / 14 at risk

Adverse event: Restlessness
Serious: no
Organ System: General disorders
Notes: distressing
Frequency: 1 affected / 14 at risk

Adverse event: other
Serious: no
Organ System: General disorders
Notes: tolerable
Frequency: 1 affected / 14 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 1 affected / 13 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Notes: distressing
Frequency: 1 affected / 13 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 2 affected / 13 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 2 affected / 13 at risk

Adverse event: nausea/vomiting
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 1 affected / 13 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 1 affected / 13 at risk

Adverse event: Increased appetite
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 3 affected / 13 at risk

Adverse event: Palpitations
Serious: no
Organ System: Cardiac disorders
Notes: tolerable
Frequency: 1 affected / 13 at risk

Adverse event: dizziness on standing
Serious: no
Organ System: Cardiac disorders
Notes: tolerable
Frequency: 3 affected / 13 at risk

Adverse event: Chest pain
Serious: no
Organ System: Cardiac disorders
Notes: tolerable
Frequency: 1 affected / 13 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: distressing
Frequency: 2 affected / 13 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: tolerable
Frequency: 1 affected / 13 at risk

Adverse event: pain with breathing
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: tolerable
Frequency: 1 affected / 13 at risk

Adverse event: increased perspiration
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: tolerable
Frequency: 1 affected / 13 at risk

Adverse event: Dry skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: tolerable
Frequency: 1 affected / 13 at risk

Adverse event: Dry skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: distressing
Frequency: 1 affected / 13 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Notes: tolerable
Frequency: 1 affected / 13 at risk

Adverse event: Tremor
Serious: no
Organ System: Nervous system disorders
Notes: distressing
Frequency: 1 affected / 13 at risk

Adverse event: poor coordination
Serious: no
Organ System: Nervous system disorders
Notes: tolerable
Frequency: 3 affected / 13 at risk

Adverse event: dizziness or lightheadedness
Serious: no
Organ System: Nervous system disorders
Notes: tolerable
Frequency: 2 affected / 13 at risk

Adverse event: numbness or tingling
Serious: no
Organ System: Nervous system disorders
Notes: tolerable
Frequency: 1 affected / 13 at risk

Adverse event: Vision blurred
Serious: no
Organ System: Eye disorders
Notes: tolerable
Frequency: 2 affected / 13 at risk

Adverse event: ringing in ear
Serious: no
Organ System: Ear and labyrinth disorders
Notes: tolerable
Frequency: 1 affected / 13 at risk

Adverse event: frequent urination
Serious: no
Organ System: Renal and urinary disorders
Notes: tolerable
Frequency: 3 affected / 13 at risk

Adverse event: Libido increased
Serious: no
Organ System: Reproductive system and breast disorders
Notes: tolerable
Frequency: 2 affected / 13 at risk

Adverse event: decreased libido
Serious: no
Organ System: Reproductive system and breast disorders
Notes: tolerable
Frequency: 1 affected / 13 at risk

Adverse event: decreased libido
Serious: no
Organ System: Reproductive system and breast disorders
Notes: distressing
Frequency: 1 affected / 13 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 3 affected / 13 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Notes: distressing
Frequency: 1 affected / 13 at risk

Adverse event: Abnormal dreams
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 4 affected / 13 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 3 affected / 13 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Notes: distressing
Frequency: 2 affected / 13 at risk

Adverse event: Hallucination
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 1 affected / 13 at risk

Adverse event: Amnesia
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 2 affected / 13 at risk

Adverse event: Amnesia
Serious: no
Organ System: Psychiatric disorders
Notes: distressing
Frequency: 1 affected / 13 at risk

Adverse event: Disturbance in attention
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 1 affected / 13 at risk

Adverse event: Disturbance in attention
Serious: no
Organ System: Psychiatric disorders
Notes: distressing
Frequency: 2 affected / 13 at risk

Adverse event: fatigue or decreased energy
Serious: no
Organ System: Psychiatric disorders
Notes: distressing
Frequency: 2 affected / 13 at risk

Adverse event: Restlessness
Serious: no
Organ System: General disorders
Notes: tolerable
Frequency: 2 affected / 13 at risk

Adverse event: Restlessness
Serious: no
Organ System: General disorders
Notes: distressing
Frequency: 2 affected / 13 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 1 affected / 17 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Notes: distressing
Frequency: 1 affected / 17 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 2 affected / 17 at risk

Adverse event: nausea/vomiting
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 1 affected / 17 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Notes: distressing
Frequency: 1 affected / 17 at risk

Adverse event: Increased appetite
Serious: no
Organ System: Gastrointestinal disorders
Notes: tolerable
Frequency: 2 affected / 17 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Gastrointestinal disorders
Notes: distressing
Frequency: 1 affected / 17 at risk

Adverse event: Palpitations
Serious: no
Organ System: Cardiac disorders
Notes: tolerable
Frequency: 1 affected / 17 at risk

Adverse event: dizziness on standing
Serious: no
Organ System: Cardiac disorders
Notes: tolerable
Frequency: 3 affected / 17 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: tolerable
Frequency: 1 affected / 17 at risk

Adverse event: Cough
Serious: no
Organ System: Reproductive system and breast disorders
Notes: distressing
Frequency: 1 affected / 17 at risk

Adverse event: increased perspiration
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: distressing
Frequency: 1 affected / 17 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: tolerable
Frequency: 1 affected / 17 at risk

Adverse event: Dry skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: tolerable
Frequency: 3 affected / 17 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Notes: tolerable
Frequency: 1 affected / 17 at risk

Adverse event: Tremor
Serious: no
Organ System: Nervous system disorders
Notes: tolerable
Frequency: 2 affected / 17 at risk

Adverse event: Tremor
Serious: no
Organ System: Nervous system disorders
Notes: distressing
Frequency: 2 affected / 17 at risk

Adverse event: poor coordination
Serious: no
Organ System: Nervous system disorders
Notes: tolerable
Frequency: 3 affected / 17 at risk

Adverse event: dizziness or lightheadedness
Serious: no
Organ System: Nervous system disorders
Notes: tolerable
Frequency: 2 affected / 17 at risk

Adverse event: numbness or tingling
Serious: no
Organ System: Nervous system disorders
Notes: tolerable
Frequency: 2 affected / 17 at risk

Adverse event: Vision blurred
Serious: no
Organ System: Eye disorders
Notes: tolerable
Frequency: 2 affected / 17 at risk

Adverse event: Vision blurred
Serious: no
Organ System: Eye disorders
Notes: distressing
Frequency: 2 affected / 17 at risk

Adverse event: ringing in ear
Serious: no
Organ System: Ear and labyrinth disorders
Notes: tolerable
Frequency: 1 affected / 17 at risk

Adverse event: difficulty urinating
Serious: no
Organ System: Renal and urinary disorders
Notes: tolerable
Frequency: 2 affected / 17 at risk

Adverse event: frequent urination
Serious: no
Organ System: Renal and urinary disorders
Notes: tolerable
Frequency: 3 affected / 17 at risk

Adverse event: decreased libido
Serious: no
Organ System: Reproductive system and breast disorders
Notes: tolerable
Frequency: 1 affected / 17 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 3 affected / 17 at risk

Adverse event: Abnormal dreams
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 1 affected / 17 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 4 affected / 17 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Notes: distressing
Frequency: 1 affected / 17 at risk

Adverse event: Hallucination
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 1 affected / 17 at risk

Adverse event: Hallucination
Serious: no
Organ System: Psychiatric disorders
Notes: distressing
Frequency: 1 affected / 17 at risk

Adverse event: Amnesia
Serious: no
Organ System: Psychiatric disorders
Notes: distressing
Frequency: 1 affected / 17 at risk

Adverse event: Disturbance in attention
Serious: no
Organ System: Psychiatric disorders
Notes: tolerable
Frequency: 3 affected / 17 at risk

Adverse event: fatigue or decreased energy
Serious: no
Organ System: General disorders
Notes: tolerable
Frequency: 3 affected / 17 at risk