TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04728347

Adverse event: Blood creatine phosphokinase increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 12 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 12 at risk

Adverse event: Rhinitis allergic
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 12 at risk

Adverse event: Ischaemic stroke
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 12 at risk

Adverse event: Vessel puncture site bruise
Serious: no
Organ System: General disorders
Frequency: 1 affected / 12 at risk

Adverse event: Lip dry
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 25 at risk

Adverse event: Ligament sprain
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 25 at risk

Adverse event: Tendon rupture
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 25 at risk

Adverse event: Rotator cuff syndrome
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 25 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 25 at risk
Study: NCT04728620

Adverse event: Hospitalisation
Serious: yes
Organ System: General disorders
Notes: Not related to study participation
Frequency: 3 affected / 50 at risk
Study: NCT04728711

Adverse event: Decreased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 8 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 8 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 8 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 8 at risk

Adverse event: Nasal congestion
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 8 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 8 at risk
Study: NCT04728802

Adverse event: Death
Serious: yes
Organ System: General disorders
Frequency: 35 affected / 317 at risk

Adverse event: Mechanical ventilation
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 5 affected / 317 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 51 affected / 317 at risk

Adverse event: Death
Serious: yes
Organ System: General disorders
Frequency: 162 affected / 328 at risk

Adverse event: Mechanical ventilation
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 41 affected / 328 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 11 affected / 328 at risk
Study: NCT04728815

Adverse event: Evidence of distress during assessments
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 9 at risk

Adverse event: Suicide attempt
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 26 at risk

Adverse event: Non-suicidal self-injury
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 26 at risk

Adverse event: Other non-mental health event
Serious: yes
Organ System: General disorders
Frequency: 2 affected / 26 at risk

Adverse event: Evidence of distress during assessments
Serious: no
Organ System: Psychiatric disorders
Frequency: 3 affected / 26 at risk

Adverse event: Suicide attempt
Serious: yes
Organ System: Psychiatric disorders
Frequency: 3 affected / 30 at risk

Adverse event: Other non-mental health event
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 30 at risk

Adverse event: Evidence of distress during assessments
Serious: no
Organ System: Psychiatric disorders
Frequency: 9 affected / 30 at risk

Adverse event: Suicide attempt
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 12 at risk

Adverse event: Suicidal ideation
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 12 at risk

Adverse event: Evidence of distress during assessments
Serious: no
Organ System: Psychiatric disorders
Frequency: 3 affected / 12 at risk
Study: NCT04729309

Adverse event: Eyelid rash
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 16 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 16 at risk

Adverse event: Aphthous ulcer
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 16 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 16 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 16 at risk

Adverse event: Catheter site pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 16 at risk

Adverse event: Incorrect dose administered
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 16 at risk

Adverse event: Infusion related reaction
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 10 affected / 16 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 16 at risk

Adverse event: Dermatitis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 16 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 16 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 6 at risk
Study: NCT04730739

Adverse event: Not Related
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: BELOW KNEE AMPUTATION FOR DEVITALIZED TISSUES AND EXTENSIVE INJURY TO LEFT KNEE.
Frequency: 1 affected / 33 at risk

Adverse event: Not Related
Serious: yes
Organ System: Infections and infestations
Notes: MAJOR COMPLICATIONS OR COMORBIDITIES COMPLICATED BY INVASIVE FUNGAL INFECTION IN ABDOMEN WITH SUBSEQUENT ISCHEMIC BOWEL, SEPSIS, AND DEATH. NO INFECTION PRESENT AT FRACTURE SITE.
Frequency: 1 affected / 33 at risk
Study: NCT04730947

Adverse event: Humerus fracture
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 1 affected / 21 at risk

Adverse event: pneumonia related to COVID-19
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 21 at risk

Adverse event: allergic food reaction
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 21 at risk

Adverse event: Hospitalisation
Serious: yes
Organ System: General disorders
Notes: Hospitalization due to patient not having someone to accompany them to hotel following catheterization
Frequency: 1 affected / 21 at risk

Adverse event: Minor bruising or bleeding following catheterization
Serious: no
Organ System: General disorders
Frequency: 2 affected / 21 at risk

Adverse event: Dizziness or dehydration
Serious: no
Organ System: General disorders
Frequency: 8 affected / 21 at risk

Adverse event: Genitourinary infections
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 21 at risk

Adverse event: Hypoglycaemia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 21 at risk

Adverse event: Worsening dyspenea
Serious: no
Organ System: General disorders
Frequency: 6 affected / 21 at risk

Adverse event: Worsening fatigue
Serious: no
Organ System: General disorders
Frequency: 3 affected / 21 at risk

Adverse event: Minor bruising or bleeding following catheterization
Serious: no
Organ System: General disorders
Frequency: 2 affected / 17 at risk

Adverse event: Dizziness or dehydration
Serious: no
Organ System: General disorders
Frequency: 2 affected / 17 at risk

Adverse event: Genitourinary infections
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 17 at risk

Adverse event: Hypoglycaemia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 17 at risk

Adverse event: Worsening dyspenea
Serious: no
Organ System: General disorders
Frequency: 7 affected / 17 at risk

Adverse event: Worsening fatigue
Serious: no
Organ System: General disorders
Frequency: 4 affected / 17 at risk

Adverse event: Medication intolerance
Serious: no
Organ System: General disorders
Frequency: 1 affected / 17 at risk
Study: NCT04731675

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 4 affected / 8 at risk

Adverse event: Face oedema
Serious: no
Organ System: General disorders
Frequency: 4 affected / 8 at risk

Adverse event: Oedema peripheral
Serious: no
Organ System: General disorders
Frequency: 3 affected / 8 at risk

Adverse event: Localised oedema
Serious: no
Organ System: General disorders
Frequency: 2 affected / 8 at risk

Adverse event: Periorbital oedema
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 8 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 4 affected / 8 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 4 affected / 8 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 8 at risk

Adverse event: Paraesthesia
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 8 at risk

Adverse event: COVID-19
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 8 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 8 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 1 affected / 3 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 3 at risk

Adverse event: COVID-19
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 3 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 3 at risk
Study: NCT04731714

Adverse event: N/A
Serious: no
Organ System: Nervous system disorders
Notes: These participants did not specify the discomfort but rated its severity as more than mild.
Frequency: 2 affected / 32 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Notes: Participant description was "like an ocular migraine without the aura."
Frequency: 1 affected / 32 at risk

Adverse event: Pruritus
Serious: no
Organ System: Nervous system disorders
Notes: Participant description was "Itching / stinging under the electrode."
Frequency: 1 affected / 32 at risk

Adverse event: N/A
Serious: no
Organ System: Nervous system disorders
Notes: These participants did not specify the discomfort but rated its severity as more than mild.
Frequency: 3 affected / 32 at risk
Study: NCT04731818

Adverse event: Hyperkalaemia
Serious: no
Organ System: Renal and urinary disorders
Notes: One TEAE, a critically high serum potassium level (6.8 mEq/L), was detected during the screening visit test was repeated and the serum potassium value was normal at 5.2 mEq/L. Deemed not related to study product or procedures.
Frequency: 1 affected / 8 at risk
Study: NCT04732624

Adverse event: GI discomfort during resuscitation
Serious: no
Organ System: Gastrointestinal disorders
Notes: Check with any nausea, vomiting, distention, diarrhea during resuscitation period i.e. 24 hours
Frequency: 8 affected / 15 at risk

Adverse event: GI discomfort during resuscitation
Serious: no
Organ System: Gastrointestinal disorders
Notes: Check with any nausea, vomiting, distention, diarrhea during resuscitation period i.e. 24 hours
Frequency: 5 affected / 15 at risk
Study: NCT04733157

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 9 affected / 611 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 29 affected / 611 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 12 affected / 611 at risk

Adverse event: Myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 613 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 16 affected / 613 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 18 affected / 613 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 14 affected / 613 at risk
Study: NCT04734197

Adverse event: Ocular hypertension not related to study drug (pre-existing condition)
Serious: yes
Organ System: Eye disorders
Notes: Pre-existing condition - the study protocol required to report "an IOP of 30 mmHg or higher" as serious adverse event (SAE). The elevated IOP at screening was reported as a mild, non-treatment emergent SAE of ocular hypertension in both eyes.
Frequency: 1 affected / 52 at risk

Adverse event: Conjuctival hyperaemia, study eye and/or fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 52 at risk

Adverse event: Instillation site pain, study eye and/or fellow eye
Serious: no
Organ System: General disorders
Frequency: 7 affected / 52 at risk

Adverse event: Conjuctival hyperaemia, study eye and/or fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 50 at risk

Adverse event: Instillation site pain, study eye and/or fellow eye
Serious: no
Organ System: General disorders
Frequency: 3 affected / 50 at risk

Adverse event: Cerebrovascular accident
Serious: yes
Organ System: Nervous system disorders
Notes: Moderate non-ocular treatment-emergent SAE that was considered by the Investigator to be unrelated to the study drug.
Frequency: 1 affected / 50 at risk

Adverse event: Conjuctival hyperaemia, study eye and/or fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 50 at risk

Adverse event: Instillation site pain, study eye and/or fellow eye
Serious: no
Organ System: General disorders
Frequency: 5 affected / 50 at risk

Adverse event: Conjuctival hyperaemia, study eye and/or fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 49 at risk

Adverse event: Conjuctival hyperaemia, study eye and/or fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 47 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Severe non-ocular treatment-emergent SAE that was considered by the Investigator to be unrelated to the study drug.
Frequency: 1 affected / 47 at risk

Adverse event: Conjuctival hyperaemia, study eye and/or fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 47 at risk

Adverse event: Instillation site pain, study eye and/or fellow eye
Serious: no
Organ System: General disorders
Frequency: 3 affected / 47 at risk

Adverse event: Conjuctival hyperaemia, study eye and/or fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 54 at risk

Adverse event: Vision blurred, study eye and/or fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 10 affected / 54 at risk

Adverse event: Instillation site pain, study eye and/or fellow eye
Serious: no
Organ System: General disorders
Frequency: 10 affected / 54 at risk

Adverse event: Instillation site pruritus, study eye and/or fellow eye
Serious: no
Organ System: General disorders
Frequency: 3 affected / 54 at risk

Adverse event: Dysgeusia
Serious: no
Organ System: Nervous system disorders
Frequency: 9 affected / 54 at risk
Study: NCT04734873

Adverse event: Abdominal hernia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 15 at risk

Adverse event: Hepatomegaly
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 15 at risk

Adverse event: Diverticulitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 15 at risk

Adverse event: Pneumonia escherichia
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 15 at risk

Adverse event: Pneumonia klebsiella
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 15 at risk

Adverse event: Skin candida
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 15 at risk

Adverse event: Hypokalaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 15 at risk

Adverse event: Amnesia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 15 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 15 at risk

Adverse event: Dyskinesia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 15 at risk

Adverse event: Myopia
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 14 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 14 at risk

Adverse event: Muscle spasms
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 14 at risk

Adverse event: Hypoaesthesia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 14 at risk

Adverse event: Presyncope
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 14 at risk

Adverse event: Tremor
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 14 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 14 at risk

Adverse event: Pollakiuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 14 at risk

Adverse event: Hyperhidrosis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 14 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 14 at risk

Adverse event: Substance-induced psychotic disorder
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 11 at risk

Adverse event: Acute respiratory distress syndrome
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 11 at risk

Adverse event: Visual impairment
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 11 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 11 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 11 at risk

Adverse event: Syncope
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 11 at risk
Study: NCT04735705

Adverse event: Streptococcus infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 47 at risk

Adverse event: E. Coli infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 47 at risk
Study: NCT04738123

Adverse event: Gastrooesophageal reflux disease
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 125 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 16 affected / 125 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 125 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 20 affected / 125 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 24 affected / 125 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 20 affected / 125 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 14 affected / 125 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 125 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 7 affected / 125 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 8 affected / 125 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 128 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 128 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 128 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 128 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 128 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 15 affected / 128 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 8 affected / 128 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 10 affected / 128 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 128 at risk
Study: NCT04738734

Adverse event: Skin Neoplasm
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Presence of non-melanoma skin cancer (SCC) was at the site of the treated lesion along with an Actinic Keratotic lesion treated with Cryotherapy. One participant showed a BCC lesion not related to treatment site.
Frequency: 1 affected / 75 at risk

Adverse event: Paraesthesia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Numbness or altered sensation at the site of treatment
Frequency: 3 affected / 75 at risk

Adverse event: Neuropathy peripheral
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Sensory disturbance including numbness or altered sensation and resolved within 2-6 days
Frequency: 2 affected / 75 at risk

Adverse event: Infection
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Suspect Skin Infection, no culture collected
Frequency: 1 affected / 75 at risk

Adverse event: Tinea versicolour
Serious: no
Organ System: Infections and infestations
Notes: Participant has recurrent fungal infections that usually have resolved within 2 months.
Frequency: 1 affected / 75 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Notes: Post-procedure pain for one participant that resolved less than 24 hours. Second participant had persistent pain post treatment that resolved within 5 months without intervention.
Frequency: 2 affected / 75 at risk

Adverse event: Skin Neoplasm
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Presence of non-melanoma skin cancer (SCC) was at the site of the treated lesion along with an Actinic Keratotic lesion treated with Cryotherapy. One participant showed a BCC lesion not related to treatment site.
Frequency: 1 affected / 75 at risk

Adverse event: Neoplasm skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Biopsy showed wart
Frequency: 1 affected / 75 at risk
Study: NCT04739709

Adverse event: Corneal oedema
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 181 at risk

Adverse event: Corneal oedema
Serious: no
Organ System: Eye disorders
Frequency: 10 affected / 197 at risk
Study: NCT04739722

Adverse event: Non-serious, Anticipated, Adverse Event
Serious: no
Organ System: Product Issues
Frequency: 1 affected / 14263 at risk
Study: NCT04739735

Adverse event: lip/cheek biting
Serious: no
Organ System: Injury, poisoning and procedural complications
Notes: due to the numbness of the soft tissues caused by local anesthetic drug injection, the child could heavily bite/injure their cheeks or lower lip unconsciously, which becomes very painful after the anesthesia effect is over.
Frequency: 8 affected / 25 at risk