TrialPanorama/TrialPanorama-database huggingface dataset:
Study: 28431480

Adverse event: metastases
Study: 28830517

Adverse event: minimal residual disease

Adverse event: minimal residual disease
Study: 25387888

Adverse event: forced expiratory volume

Adverse event: forced expiratory volume
Study: 22014970

Adverse event: pain

Adverse event: pain
Study: 12506181

Adverse event: nausea

Adverse event: nausea
Study: 11463999

Adverse event: weight

Adverse event: mass
Study: 9923569

Adverse event: heart rate

Adverse event: heart rate
Study: 8067223

Adverse event: ejection fraction

Adverse event: stroke volume

Adverse event: cardiac output

Adverse event: heart rate
Study: 3057512

Adverse event: pain
Study: 31216547

Adverse event: muscle mass

Adverse event: waist circumference decreased

Adverse event: mass

Adverse event: waist circumference

Adverse event: muscle mass

Adverse event: waist circumference decreased

Adverse event: mass

Adverse event: blood pressure increased

Adverse event: waist circumference
Study: 25925999

Adverse event: surgery

Adverse event: surgery
Study: 18760803

Adverse event: respiratory rate

Adverse event: respiratory rate increased
Study: 15770435

Adverse event: illness
Study: 9032500

Adverse event: infection
Study: 8389738

Adverse event: mean arterial pressure

Adverse event: mean arterial pressure
Study: 28755622

Adverse event: suicidal ideation

Adverse event: suicidal ideation

Adverse event: suicidal ideation
Study: 18806703

Adverse event: vomiting
Study: 30397706

Adverse event: heart rate
Study: 14657066

Adverse event: rash
Study: 8784310

Adverse event: fistula

Adverse event: fistula
Study: 1622858

Adverse event: chemotherapy
Study: 30397706

Adverse event: heart rate

Adverse event: heart rate
Study: 25155138

Adverse event: transfusion

Adverse event: transfusion
Study: 20432816

Adverse event: insulin resistance

Adverse event: insulin resistance

Adverse event: insulin resistance
Study: 17980248

Adverse event: weight

Adverse event: weight

Adverse event: hypotension

Adverse event: infusion

Adverse event: hypotension

Adverse event: infusion

Adverse event: death

Adverse event: death
Study: 12564092

Adverse event: hypertension

Adverse event: surgery

Adverse event: hypertension

Adverse event: surgery
Study: 9839299

Adverse event: disability
Study: 2674034

Adverse event: heart rate
Study: 5100372

Adverse event: fasting
Study: 31773402

Adverse event: osteoporosis

Adverse event: fracture
Study: 29044408

Adverse event: osteoarthritis
Study: 26356395

Adverse event: asthenia

Adverse event: indifference

Adverse event: sedation

Adverse event: memory impairment
Study: 23164702

Adverse event: hunger

Adverse event: overweight

Adverse event: hunger
Study: 19748294

Adverse event: pain
Study: 1573097

Adverse event: stress

Adverse event: stress
Study: 25852208

Adverse event: weight

Adverse event: weight
Study: 24375206

Adverse event: substance use
Study: 17143968

Adverse event: pain

Adverse event: pain
Study: 11375835

Adverse event: extubation

Adverse event: extubation
Study: 9660108

Adverse event: depressed mood
Study: 2551397

Adverse event: dissociation

Adverse event: stress

Adverse event: stress

Adverse event: illness
Study: 31441419

Adverse event: transferrin increased

Adverse event: transferrin

Adverse event: transferrin increased

Adverse event: transferrin

Adverse event: mechanical ventilation

Adverse event: aspiration

Adverse event: pneumonia
Study: 25175554

Adverse event: acupressure
Study: 6101174

Adverse event: tremor

Adverse event: tremor
Study: 21741469

Adverse event: discomfort
Study: 19560329

Adverse event: depression

Adverse event: depression
Study: 11551575

Adverse event: hypersensitivity

Adverse event: discharge
Study: 27472478

Adverse event: weight

Adverse event: weight

Adverse event: weight

Adverse event: weight
Study: 24395308

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 16827683

Adverse event: hypertrophy

Adverse event: transplant

Adverse event: hypertension

Adverse event: infection

Adverse event: diabetes mellitus
Study: 10026457

Adverse event: stress

Adverse event: stress
Study: 1660610

Adverse event: heart rate

Adverse event: heart rate increased

Adverse event: heart rate
Study: 6346939

Adverse event: stress

Adverse event: stress
Study: 17056362

Adverse event: cataract
Study: 25792802

Adverse event: adhesion

Adverse event: skin adhesion
Study: 23506277

Adverse event: pain
Study: 21455087

Adverse event: hypotension

Adverse event: discharge

Adverse event: infection

Adverse event: wound
Study: 14652116

Adverse event: surgery
Study: 10694547

Adverse event: pneumonitis
Study: 9066326

Adverse event: skin temperature

Adverse event: skin temperature

Adverse event: skin temperature
Study: 8259746

Adverse event: delivery

Adverse event: delivery

Adverse event: intensive care

Adverse event: weight

Adverse event: respiratory distress
Study: 30091852

Adverse event: headache

Adverse event: nausea

Adverse event: headache

Adverse event: nausea
Study: 29909400

Adverse event: residual urine volume

Adverse event: incontinence

Adverse event: urinary incontinence

Adverse event: nocturia
Study: 11459433

Adverse event: adhesion

Adverse event: adhesion

Adverse event: adhesion
Study: 3177753

Adverse event: surgery
Study: 31012853

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction
Study: 28337847

Adverse event: weight

Adverse event: weight

Adverse event: weight

Adverse event: weight

Adverse event: weight

Adverse event: weight
Study: 16429430

Adverse event: oxygen saturation
Study: 12624628

Adverse event: anticoagulant therapy

Adverse event: anticoagulant therapy
Study: 10673512

Adverse event: fatigue

Adverse event: headache

Adverse event: nausea
Study: 8862237

Adverse event: weight
Study: 16429430

Adverse event: oxygen consumption
Study: 29143355

Adverse event: physical disability

Adverse event: pain

Adverse event: disability

Adverse event: pain

Adverse event: pain
Study: 26964901

Adverse event: pain
Study: 25823187

Adverse event: weight

Adverse event: weight

Adverse event: delivery

Adverse event: pregnancy

Adverse event: apgar score
Study: 22906948

Adverse event: acupuncture
Study: 18714219

Adverse event: fatigue

Adverse event: fatigue
Study: 15671428

Adverse event: cardiac arrest

Adverse event: cardiogenic shock

Adverse event: shock

Adverse event: cardiogenic shock

Adverse event: shock
Study: 10585975

Adverse event: discharge

Adverse event: weight

Adverse event: sepsis
Study: 1832261

Adverse event: cardiac arrhythmias

Adverse event: cardiac arrhythmias

Adverse event: heart rate

Adverse event: heart rate
Study: 15671428

Adverse event: cardiac arrest
Study: 8545227

Adverse event: gastroenteritis
Study: 24944134

Adverse event: mass

Adverse event: mass
Study: 15818718

Adverse event: sick leave

Adverse event: sick leave

Adverse event: disability

Adverse event: sick leave

Adverse event: disability
Study: 12766097

Adverse event: wound closure

Adverse event: wound

Adverse event: wound closure

Adverse event: wound
Study: 10571355

Adverse event: discomfort

Adverse event: pain

Adverse event: discomfort

Adverse event: pain
Study: 8545227

Adverse event: illness

Adverse event: gastroenteritis
Study: 1859055

Adverse event: bronchitis

Adverse event: bronchitis

Adverse event: bronchitis
Study: 15179210

Adverse event: heart rate

Adverse event: heart rate
Study: 31226721

Adverse event: death

Adverse event: troponin t

Adverse event: myocardial injury

Adverse event: troponin

Adverse event: injury

Adverse event: death

Adverse event: troponin t

Adverse event: myocardial injury

Adverse event: troponin

Adverse event: injury

Adverse event: death

Adverse event: troponin t

Adverse event: myocardial injury

Adverse event: troponin

Adverse event: injury
Study: 25532433

Adverse event: lymphadenectomy

Adverse event: lymphadenectomy

Adverse event: lymphadenectomy

Adverse event: lymphadenectomy
Study: 22460183

Adverse event: proteinuria
Study: 21570870

Adverse event: restenosis

Adverse event: restenosis

Adverse event: restenosis

Adverse event: amputation
Study: 18496519

Adverse event: stress
Study: 17215606

Adverse event: weight

Adverse event: infant

Adverse event: infant
Study: 11180027

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: dysphoria

Adverse event: sedation

Adverse event: dysphoria

Adverse event: sedation

Adverse event: dysphoria

Adverse event: sedation

Adverse event: dysphoria

Adverse event: sedation

Adverse event: dysphoria

Adverse event: sedation

Adverse event: depression

Adverse event: respiratory depression

Adverse event: depression

Adverse event: respiratory depression

Adverse event: depression

Adverse event: respiratory depression
Study: 9382506

Adverse event: ileus

Adverse event: stenosis

Adverse event: ileal stenosis

Adverse event: pain

Adverse event: abdominal pain
Study: 3706373

Adverse event: anxiety

Adverse event: anxiety

Adverse event: anxiety

Adverse event: anxiety

Adverse event: anxiety
Study: 26995778

Adverse event: pain

Adverse event: pain
Study: 15897362

Adverse event: pulse wave velocity

Adverse event: mean arterial pressure
Study: 14570950

Adverse event: acne

Adverse event: rash
Study: 8678385

Adverse event: discharge

Adverse event: discharge

Adverse event: sneezing

Adverse event: sneezing

Adverse event: nasal dryness
Study: 30842084

Adverse event: fundus autofluorescence

Adverse event: scan
Study: 29342952

Adverse event: sick leave

Adverse event: sick leave
Study: 26228164

Adverse event: depression

Adverse event: anxiety

Adverse event: depression

Adverse event: anxiety

Adverse event: depression

Adverse event: anxiety
Study: 578480

Adverse event: epinephrine

Adverse event: platelet count

Adverse event: epinephrine
Study: 31225537

Adverse event: fluorosis
Study: 24955752

Adverse event: depressive symptom

Adverse event: depressive symptom
Study: 16970163

Adverse event: depression

Adverse event: anxiety
Study: 11583866

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death

Adverse event: death
Study: 9422950

Adverse event: infection

Adverse event: infection
Study: 21979185

Adverse event: enterocele

Adverse event: rectocele

Adverse event: defecography

Adverse event: enterocele

Adverse event: intussusception

Adverse event: rectocele
Study: 8623999

Adverse event: anxiety

Adverse event: anxiety
Study: 24891317

Adverse event: inflammation

Adverse event: inflammation
Study: 21970137

Adverse event: agitation

Adverse event: agitation

Adverse event: agitation
Study: 19706558

Adverse event: eye irritation

Adverse event: erythema

Adverse event: application site erythema
Study: 8103144

Adverse event: pain

Adverse event: pain

Adverse event: wound

Adverse event: pain

Adverse event: wound
Study: 3526085

Adverse event: breast tenderness

Adverse event: tenderness
Study: 15023154

Adverse event: prophylaxis

Adverse event: neutropenia
Study: 11713941

Adverse event: viral load

Adverse event: viral load
Study: 9236422

Adverse event: angioplasty

Adverse event: angioplasty

Adverse event: atherectomy

Adverse event: angioplasty

Adverse event: atherectomy

Adverse event: angioplasty

Adverse event: angioplasty

Adverse event: atherectomy
Study: 8213711

Adverse event: cholecystectomy
Study: 25810849

Adverse event: epinephrine
Study: 17945539

Adverse event: seizure
Study: 15483207

Adverse event: weight

Adverse event: weight

Adverse event: weight

Adverse event: depression

Adverse event: weight

Adverse event: weight
Study: 22782386

Adverse event: pain

Adverse event: pain
Study: 20083627

Adverse event: death
Study: 12543742

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: injection

Adverse event: fear

Adverse event: fear of injection

Adverse event: injection

Adverse event: fear

Adverse event: fear of injection

Adverse event: pain

Adverse event: pain
Study: 10389775

Adverse event: heart rate

Adverse event: heart rate
Study: 8537982

Adverse event: bile acids

Adverse event: bile acids
Study: 6337357

Adverse event: infection

Adverse event: infection
Study: 29183873

Adverse event: blood glucose

Adverse event: blood glucose
Study: 11791035

Adverse event: proteinuria

Adverse event: proteinuria

Adverse event: proteinuria

Adverse event: proteinuria
Study: 31654268

Adverse event: mass

Adverse event: inflammation
Study: 22865576

Adverse event: culture

Adverse event: culture
Study: 20677478

Adverse event: pregnancy

Adverse event: pregnancy
Study: 15958334

Adverse event: infection

Adverse event: infection
Study: 9667603

Adverse event: elderly
Study: 8208596

Adverse event: oxygen saturation

Adverse event: oxygen saturation
Study: 24046993

Adverse event: depression

Adverse event: respiratory depression

Adverse event: depression

Adverse event: respiratory depression
Study: 11889279

Adverse event: condom

Adverse event: condom

Adverse event: condom

Adverse event: condom
Study: 7933040

Adverse event: hernia
Study: 28495681

Adverse event: syphilis

Adverse event: syphilis
Study: 25475927

Adverse event: stress
Study: 20839290

Adverse event: injection
Study: 17443126

Adverse event: schizophrenia
Study: 12616259

Adverse event: weight

Adverse event: weight

Adverse event: weight

Adverse event: weight
Study: 10675165

Adverse event: influenza

Adverse event: infection

Adverse event: influenza

Adverse event: infection
Study: 26211411

Adverse event: discharge
Study: 24424070

Adverse event: transfusion

Adverse event: transfusion

Adverse event: transfusion

Adverse event: transfusion
Study: 22703892

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 19199542

Adverse event: treatment failure

Adverse event: treatment failure

Adverse event: treatment failure

Adverse event: malaria

Adverse event: treatment failure

Adverse event: treatment failure
Study: 7963709

Adverse event: beta 2 microglobulin
Study: 28817828

Adverse event: fall

Adverse event: fall
Study: 18419825

Adverse event: mean arterial pressure

Adverse event: heart rate

Adverse event: respiratory rate

Adverse event: cardiac output

Adverse event: heart rate

Adverse event: respiratory rate

Adverse event: base excess

Adverse event: blood ph
Study: 14984503

Adverse event: haemoglobin

Adverse event: infusion
Study: 11053917

Adverse event: skin irritation

Adverse event: skin irritation
Study: 2868657

Adverse event: aneurysm

Adverse event: hypertension

Adverse event: low density lipoprotein
Study: 25442396

Adverse event: intensive care
Study: 21718474

Adverse event: pneumonitis

Adverse event: pneumonitis

Adverse event: infection

Adverse event: mechanical ventilation

Adverse event: infection

Adverse event: mechanical ventilation
Study: 15452309

Adverse event: headaches

Adverse event: headaches
Study: 2825856

Adverse event: chemotherapy

Adverse event: chemotherapy

Adverse event: chemotherapy
Study: 27487492

Adverse event: pain
Study: 19751326

Adverse event: delivery
Study: 15363071

Adverse event: shock

Adverse event: shock

Adverse event: atrial fibrillation

Adverse event: sinus tachycardia

Adverse event: tachycardia
Study: 11920260

Adverse event: death

Adverse event: thrombocytopenia

Adverse event: death

Adverse event: thrombocytopenia

Adverse event: death

Adverse event: thrombocytopenia
Study: 9682526

Adverse event: fear

Adverse event: fear
Study: 2911997

Adverse event: vitamin e

Adverse event: vitamin e

Adverse event: vitamin e
Study: 30732912

Adverse event: weight

Adverse event: binge eating

Adverse event: weight

Adverse event: binge eating
Study: 31628790

Adverse event: weight
Study: 28323947

Adverse event: carotene

Adverse event: weight

Adverse event: carotene
Study: 17044952

Adverse event: disability
Study: 9471828

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 8398330

Adverse event: metastases
Study: 3908435

Adverse event: genital herpes
Study: 27568492

Adverse event: pain

Adverse event: discharge
Study: 24265189

Adverse event: disability

Adverse event: disability
Study: 21712736

Adverse event: high density lipoprotein

Adverse event: high density lipoprotein

Adverse event: high density lipoprotein

Adverse event: high density lipoprotein
Study: 12269674

Adverse event: haemoglobin

Adverse event: haemoglobin
Study: 319140

Adverse event: injection

Adverse event: injection
Study: 22869943

Adverse event: extubation
Study: 20727552

Adverse event: incontinence

Adverse event: incontinence
Study: 18280710

Adverse event: amenorrhoea

Adverse event: weight
Study: 16897618

Adverse event: pain

Adverse event: pain
Study: 12527665

Adverse event: depression

Adverse event: anxiety
Study: 8851458

Adverse event: pain

Adverse event: weight

Adverse event: pain
Study: 1510191

Adverse event: pain

Adverse event: pain
Study: 6486489

Adverse event: visual analogue scale
Study: 28437570

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: acupressure
Study: 22947355

Adverse event: adrenal insufficiency
Study: 19655244

Adverse event: pain

Adverse event: disability
Study: 17636513

Adverse event: surgery
Study: 31860096

Adverse event: death

Adverse event: dialysis
Study: 25739520

Adverse event: condom
Study: 20670096

Adverse event: apolipoprotein b

Adverse event: apolipoprotein
Study: 11269574

Adverse event: headache
Study: 9552067

Adverse event: nausea

Adverse event: nausea

Adverse event: nausea
Study: 7836534

Adverse event: pregnancy

Adverse event: pregnancy
Study: 2975554

Adverse event: blood glucose

Adverse event: fasting

Adverse event: blood glucose

Adverse event: fasting
Study: 31433717

Adverse event: cystatin c

Adverse event: chronic kidney disease

Adverse event: renal replacement therapy
Study: 27056996

Adverse event: fatigue

Adverse event: alanine aminotransferase
Study: 24553886

Adverse event: wound

Adverse event: wound

Adverse event: fractures
Study: 22382665

Adverse event: heart rate
Study: 14693585

Adverse event: agitation

Adverse event: agitation

Adverse event: agitation
Study: 9078199

Adverse event: sinusitis

Adverse event: sinusitis
Study: 3065083

Adverse event: tidal volume decreased

Adverse event: tidal volume

Adverse event: carbon dioxide

Adverse event: carbon dioxide
Study: 31074005

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 25933183

Adverse event: irritability

Adverse event: crying

Adverse event: tenderness

Adverse event: vomiting

Adverse event: swelling

Adverse event: induration

Adverse event: irritability

Adverse event: crying

Adverse event: tenderness

Adverse event: vomiting

Adverse event: swelling

Adverse event: induration
Study: 23160979

Adverse event: anaesthesia

Adverse event: anaesthesia

Adverse event: pain
Study: 21667141

Adverse event: alcohol use

Adverse event: alcohol use
Study: 16521674

Adverse event: pain

Adverse event: pain

Adverse event: acupuncture
Study: 15225149

Adverse event: metabolic syndrome

Adverse event: metabolic syndrome

Adverse event: fasting

Adverse event: metabolic syndrome
Study: 11765591

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 9422901

Adverse event: haemodilution
Study: 7684551

Adverse event: fasting

Adverse event: thyroxine

Adverse event: weight
Study: 29663316

Adverse event: colostomy

Adverse event: colostomy
Study: 26245752

Adverse event: pregnancy

Adverse event: unintended pregnancy
Study: 23054109

Adverse event: swelling

Adverse event: swelling
Study: 21739234

Adverse event: hernia

Adverse event: inguinal hernia

Adverse event: hernia

Adverse event: inguinal hernia

Adverse event: hernia

Adverse event: inguinal hernia
Study: 16829296

Adverse event: illness

Adverse event: illness
Study: 9178340

Adverse event: heart rate

Adverse event: stress

Adverse event: heart rate

Adverse event: cardiac output

Adverse event: stress

Adverse event: heart rate

Adverse event: cardiac output
Study: 3516104

Adverse event: bleeding time
Study: 31802921

Adverse event: emotional distress

Adverse event: emotional distress
Study: 29588050

Adverse event: oppositional defiant disorder
Study: 11669328

Adverse event: chemotherapy

Adverse event: injury

Adverse event: tissue injury

Adverse event: treatment failure
Study: 2691100

Adverse event: restenosis

Adverse event: restenosis

Adverse event: restenosis

Adverse event: restenosis

Adverse event: restenosis

Adverse event: restenosis
Study: 31930507

Adverse event: anxiety

Adverse event: compulsions
Study: 29095069

Adverse event: visual analogue scale

Adverse event: anxiety

Adverse event: visual analogue scale

Adverse event: anxiety
Study: 16316969

Adverse event: atrioventricular block

Adverse event: hypotension

Adverse event: bradycardia

Adverse event: vomiting

Adverse event: nausea
Study: 11874387

Adverse event: heart rate

Adverse event: heart rate
Study: 9798810

Adverse event: discomfort
Study: 6136936

Adverse event: hangover

Adverse event: heart rate

Adverse event: heart rate increased

Adverse event: heart rate
Study: 31892489

Adverse event: thrombocytopenia
Study: 26897614

Adverse event: substance use

Adverse event: substance use

Adverse event: substance use

Adverse event: substance use

Adverse event: injury
Study: 23511299

Adverse event: viral load
Study: 11369066

Adverse event: dermatitis
Study: 28174153

Adverse event: pain

Adverse event: haemorrhage

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 25809236

Adverse event: hunger

Adverse event: hunger

Adverse event: fasting
Study: 21751435

Adverse event: paresis

Adverse event: discharge

Adverse event: paresis

Adverse event: discharge

Adverse event: pain

Adverse event: pain
Study: 15504180

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 9261520

Adverse event: hospitalisation

Adverse event: vomiting

Adverse event: nausea

Adverse event: alopecia
Study: 31486158

Adverse event: organ failure

Adverse event: mechanical ventilation

Adverse event: organ failure

Adverse event: mechanical ventilation
Study: 31934995

Adverse event: scan

Adverse event: scan

Adverse event: scan

Adverse event: scan
Study: 28118668

Adverse event: fatigue

Adverse event: fatigue

Adverse event: pain
Study: 22082677

Adverse event: placenta growth factor
Study: 19129911

Adverse event: pregnancy

Adverse event: sexual activity increased

Adverse event: pregnancy
Study: 11736878

Adverse event: weight
Study: 3092310

Adverse event: tetanus
Study: 25459040

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction
Study: 22317838

Adverse event: nystagmus
Study: 20538833

Adverse event: chronic kidney disease
Study: 18713932

Adverse event: pain

Adverse event: pain
Study: 12915697

Adverse event: infusion
Study: 8792761

Adverse event: depression
Study: 31972580

Adverse event: amputation
Study: 29719839

Adverse event: fistula

Adverse event: infection

Adverse event: wound

Adverse event: wound infection

Adverse event: fistula

Adverse event: infection

Adverse event: wound

Adverse event: wound infection
Study: 26294138

Adverse event: encephalopathy

Adverse event: metabolic encephalopathy
Study: 22315948

Adverse event: infarction

Adverse event: infarction
Study: 15316907

Adverse event: cancer screening

Adverse event: cancer screening
Study: 11936356

Adverse event: graft infection

Adverse event: infection

Adverse event: wound

Adverse event: graft infection

Adverse event: infection

Adverse event: graft infection

Adverse event: infection
Study: 2574766

Adverse event: body temperature

Adverse event: injection
Study: 1183792

Adverse event: thrombophlebitis

Adverse event: thrombophlebitis

Adverse event: embolism

Adverse event: pulmonary embolism
Study: 30915723

Adverse event: fracture

Adverse event: bone loss

Adverse event: fractures

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: fracture
Study: 28633157

Adverse event: weight

Adverse event: tidal volume