Study: NCT00580372

Adverse event: Blood/bone marrow Grade 4
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 155 affected / 231 at risk

Adverse event: Anemia Grade 4
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 10 affected / 231 at risk

Adverse event: Neutropeni Grade 4
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 136 affected / 231 at risk

Adverse event: WBC Grade 4
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 150 affected / 231 at risk

Adverse event: Thrombocyt Grade 4
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 37 affected / 231 at risk

Adverse event: Hepatobiliary/pancreas grade 3
Serious: yes
Organ System: Endocrine disorders
Frequency: 41 affected / 231 at risk

Adverse event: Hepatobiliary/pancreas grade 4
Serious: yes
Organ System: Endocrine disorders
Frequency: 1 affected / 231 at risk

Adverse event: Alkaline grade 3
Serious: yes
Organ System: Endocrine disorders
Frequency: 5 affected / 231 at risk

Adverse event: Bilirubin grade 3
Serious: yes
Organ System: Endocrine disorders
Frequency: 12 affected / 231 at risk

Adverse event: Bilirubin grade 4
Serious: yes
Organ System: Endocrine disorders
Frequency: 1 affected / 231 at risk

Adverse event: Hypoalbumi grade 3
Serious: yes
Organ System: Endocrine disorders
Frequency: 26 affected / 231 at risk

Adverse event: SGOT (AST) grade 3
Serious: yes
Organ System: Endocrine disorders
Frequency: 4 affected / 231 at risk

Adverse event: SGPT (ALT) grade 3
Serious: yes
Organ System: Endocrine disorders
Frequency: 8 affected / 231 at risk

Adverse event: Metabolic/laboratory grade 3
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 89 affected / 231 at risk

Adverse event: Metabolic/laboratory grade 4
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 28 affected / 231 at risk

Adverse event: Bicarbonat grade 3
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 231 at risk

Adverse event: Hypercalce grade 3
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 3 affected / 231 at risk

Adverse event: Hypercalce grade 4
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 231 at risk

Adverse event: Hyperglyce grade 3
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 15 affected / 231 at risk

Adverse event: Hyperglyce grade 4
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 6 affected / 231 at risk

Adverse event: Hyperkalem grade 3
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 7 affected / 231 at risk

Adverse event: Hyperkalem grade 4
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 3 affected / 231 at risk

Adverse event: Hypermagne grade 3
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 231 at risk

Adverse event: Hypematre grade 3
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 231 at risk

Adverse event: Hypematre grade 4
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 231 at risk

Adverse event: Hypocalcem grade 3
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 11 affected / 231 at risk

Adverse event: Hypocalcem grade 4
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 10 affected / 231 at risk

Adverse event: Hypokalemi grade 3
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 39 affected / 231 at risk

Adverse event: Hypokalemi grade 4
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 3 affected / 231 at risk

Adverse event: Hypomagnes grade 3
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 231 at risk

Adverse event: Hypomagnes grade 4
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 231 at risk

Adverse event: Hyponatrem grade 3
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 34 affected / 231 at risk

Adverse event: Hyponatrem grade 4
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 231 at risk

Adverse event: Hypophosph grade 3
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 83 affected / 231 at risk

Adverse event: Hypophosph grade 4
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 231 at risk

Adverse event: Renal/Genitourinary grade 3
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 14 affected / 231 at risk

Adverse event: Renal/Genitourinary grade 4
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 9 affected / 231 at risk

Adverse event: Creatinine grade 3
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 14 affected / 231 at risk

Adverse event: Creatinine grade 4
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 9 affected / 231 at risk

Adverse event: Anemia grade 2
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 52 affected / 231 at risk

Adverse event: Thrombocyt grade 2
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 34 affected / 231 at risk

Adverse event: Hepatobiliary/ pancreas grade 1
Serious: no
Organ System: Endocrine disorders
Frequency: 30 affected / 231 at risk

Adverse event: Hepatobiliary/pancreas grade 2
Serious: no
Organ System: Endocrine disorders
Frequency: 138 affected / 231 at risk

Adverse event: Alkaline grade 1
Serious: no
Organ System: Endocrine disorders
Frequency: 70 affected / 231 at risk

Adverse event: Alkaline grade 2
Serious: no
Organ System: Endocrine disorders
Frequency: 14 affected / 231 at risk

Adverse event: Bilirubin grade 1
Serious: no
Organ System: Endocrine disorders
Frequency: 38 affected / 231 at risk

Adverse event: Bilirubin grade 2
Serious: no
Organ System: Endocrine disorders
Frequency: 17 affected / 231 at risk

Adverse event: Hypoalbumi grade 1
Serious: no
Organ System: Endocrine disorders
Frequency: 34 affected / 231 at risk

Adverse event: Hypoalbumi grade 2
Serious: no
Organ System: Endocrine disorders
Frequency: 150 affected / 231 at risk

Adverse event: SGOT (AST) grade 1
Serious: no
Organ System: Endocrine disorders
Frequency: 78 affected / 231 at risk

Adverse event: SGOT (AST) grade 2
Serious: no
Organ System: Endocrine disorders
Frequency: 13 affected / 231 at risk

Adverse event: SGPT (ALT) grade 1
Serious: no
Organ System: Endocrine disorders
Frequency: 76 affected / 231 at risk

Adverse event: SGPT (ALT) grade 2
Serious: no
Organ System: Endocrine disorders
Frequency: 20 affected / 231 at risk

Adverse event: Metabolic/laboratory grade 2
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 38 affected / 231 at risk

Adverse event: Bicarbonat grade 1
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 97 affected / 231 at risk

Adverse event: Hypercalce grade 1
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 17 affected / 231 at risk

Adverse event: Hyperglyce grade 1
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 53 affected / 231 at risk

Adverse event: Hyperglyce grade 2
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 55 affected / 231 at risk

Adverse event: Hyperkalem grade 1
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 43 affected / 231 at risk

Adverse event: Hyperkalem grade 2
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 29 affected / 231 at risk

Adverse event: Hypemagne grade 1
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 27 affected / 231 at risk

Adverse event: Hypematre grade 1
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 63 affected / 231 at risk

Adverse event: Hypocalcem grade 1
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 71 affected / 231 at risk

Adverse event: Hypocalcem grade 2
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 57 affected / 231 at risk

Adverse event: Hypokalemi grade 1
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 105 affected / 231 at risk

Adverse event: Hypomagnes grade 1
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 116 affected / 231 at risk

Adverse event: Hypomagnes grade 2
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 25 affected / 231 at risk

Adverse event: Hyponatrem grade 1
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 97 affected / 231 at risk

Adverse event: Hypophosph grade 2
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 63 affected / 231 at risk

Adverse event: Renal/genitourinary grade 1
Serious: no
Organ System: Renal and urinary disorders
Frequency: 64 affected / 231 at risk

Adverse event: Renal/genitourinary grade 2
Serious: no
Organ System: Renal and urinary disorders
Frequency: 35 affected / 231 at risk

Adverse event: Creatinine grade 1
Serious: no
Organ System: Renal and urinary disorders
Frequency: 64 affected / 231 at risk

Adverse event: Creatinine grade 2
Serious: no
Organ System: Renal and urinary disorders
Frequency: 35 affected / 231 at risk