TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04195594

Adverse event: Acne
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 14 at risk

Adverse event: Amenorrhoea
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 14 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 14 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 14 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 14 at risk

Adverse event: Haemoglobin decreased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 14 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 14 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 14 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 14 at risk

Adverse event: Malaise
Serious: no
Organ System: General disorders
Frequency: 2 affected / 14 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 14 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 14 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 14 at risk

Adverse event: Irritability
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 14 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 14 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 14 at risk

Adverse event: Mood altered
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 14 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 14 at risk

Adverse event: Limb injury
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 14 at risk

Adverse event: Sleep disorder
Serious: no
Organ System: Psychiatric disorders
Frequency: 4 affected / 14 at risk

Adverse event: Insomnia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 14 at risk

Adverse event: Sunburn
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 14 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 14 at risk

Adverse event: Abdominal discomfort
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 14 at risk

Adverse event: Vessel puncture site bruise
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 14 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 14 at risk
Study: NCT04195893

Adverse event: Conjuctival Staining
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 55 at risk
Study: NCT04195958

Adverse event: General Disorders
Serious: no
Organ System: General disorders
Frequency: 2 affected / 3 at risk
Study: NCT04196023

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Notes: abdominal pain
Frequency: 1 affected / 62 at risk

Adverse event: may interact with blood pressure medication
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 62 at risk

Adverse event: weight gain, migraine and swelling with arthritic pain in fingers
Serious: no
Organ System: General disorders
Frequency: 1 affected / 62 at risk

Adverse event: feel sick
Serious: no
Organ System: General disorders
Frequency: 1 affected / 62 at risk

Adverse event: some bleeding after the rectal biopsy procedure
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 67 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Notes: abdominal pain
Frequency: 1 affected / 67 at risk
Study: NCT04196140

Adverse event: Hypoglycaemia
Serious: yes
Organ System: Endocrine disorders
Frequency: 3 affected / 240 at risk

Adverse event: Diabetic ketoacidosis
Serious: yes
Organ System: Endocrine disorders
Frequency: 1 affected / 240 at risk

Adverse event: Other
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 240 at risk

Adverse event: Hypoglycaemia
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 240 at risk

Adverse event: Prolonged Hyperglycemia
Serious: no
Organ System: Endocrine disorders
Frequency: 18 affected / 240 at risk

Adverse event: Other
Serious: no
Organ System: Investigations
Frequency: 14 affected / 240 at risk

Adverse event: Hyperglycaemia
Serious: no
Organ System: Endocrine disorders
Frequency: 3 affected / 240 at risk

Adverse event: Hypoglycaemia
Serious: yes
Organ System: Endocrine disorders
Frequency: 7 affected / 224 at risk

Adverse event: Diabetic ketoacidosis
Serious: yes
Organ System: Endocrine disorders
Frequency: 1 affected / 224 at risk

Adverse event: Other
Serious: yes
Organ System: Investigations
Frequency: 9 affected / 224 at risk

Adverse event: Hypoglycaemia
Serious: yes
Organ System: Endocrine disorders
Frequency: 1 affected / 224 at risk

Adverse event: Prolonged Hyperglycemia
Serious: yes
Organ System: Endocrine disorders
Frequency: 1 affected / 224 at risk

Adverse event: Prolonged Hyperglycemia
Serious: no
Organ System: Endocrine disorders
Frequency: 40 affected / 224 at risk

Adverse event: Other
Serious: no
Organ System: Investigations
Frequency: 58 affected / 224 at risk

Adverse event: Hyperglycaemia
Serious: no
Organ System: Endocrine disorders
Frequency: 9 affected / 224 at risk
Study: NCT04196803

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Notes: abdominal pain, stomach hurt
Frequency: 1 affected / 124 at risk

Adverse event: Feel sick
Serious: no
Organ System: General disorders
Frequency: 1 affected / 124 at risk

Adverse event: Arthritic pain in fingers
Serious: no
Organ System: General disorders
Frequency: 1 affected / 124 at risk

Adverse event: Weight increased
Serious: no
Organ System: General disorders
Notes: 10 pound weight gain
Frequency: 1 affected / 124 at risk

Adverse event: Interaction with blood pressure medication
Serious: no
Organ System: Vascular disorders
Notes: may be having an adverse effect on blood pressure medication
Frequency: 1 affected / 124 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Notes: abdominal pain, stomach hurt
Frequency: 2 affected / 126 at risk

Adverse event: Bleeding after the rectal biopsy procedure
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 126 at risk
Study: NCT04197336

Adverse event: Ucler
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Deep gastric ulcer
Frequency: 1 affected / 10 at risk

Adverse event: Insomnia
Serious: yes
Organ System: General disorders
Notes: Insomnia
Frequency: 1 affected / 10 at risk

Adverse event: Site pseudoaneurysm
Serious: yes
Organ System: Vascular disorders
Notes: Embolization-unrelated vascular access site pseudoaneurysm
Frequency: 1 affected / 10 at risk
Study: NCT04197869

Adverse event: loose stool
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 24 at risk
Study: NCT04198363

Adverse event: Arrhythmia supraventricular
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 256 at risk

Adverse event: Fibroadenoma of breast
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Notes: Number of participants at risk represents the female population in this study.
Frequency: 1 affected / 151 at risk

Adverse event: Lung neoplasm malignant
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 256 at risk

Adverse event: Faeces discoloured
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 13 affected / 256 at risk

Adverse event: Hepatic function abnormal
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 17 affected / 256 at risk

Adverse event: Protein urine present
Serious: no
Organ System: Investigations
Frequency: 18 affected / 256 at risk

Adverse event: Dysgeusia
Serious: no
Organ System: Nervous system disorders
Frequency: 83 affected / 256 at risk

Adverse event: Chronic gastritis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 254 at risk

Adverse event: Enteritis infectious
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 254 at risk

Adverse event: Meniscus injury
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 254 at risk

Adverse event: Cervical dysplasia
Serious: yes
Organ System: Reproductive system and breast disorders
Notes: Number of participants at risk represents the female population in this study.
Frequency: 1 affected / 164 at risk

Adverse event: Ovarian cyst ruptured
Serious: yes
Organ System: Reproductive system and breast disorders
Notes: Number of participants at risk represents the female population in this study.
Frequency: 1 affected / 164 at risk

Adverse event: Drug eruption
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 254 at risk

Adverse event: Faeces discoloured
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 8 affected / 254 at risk

Adverse event: Hepatic function abnormal
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 9 affected / 254 at risk

Adverse event: Protein urine present
Serious: no
Organ System: Investigations
Frequency: 15 affected / 254 at risk

Adverse event: Dysgeusia
Serious: no
Organ System: Nervous system disorders
Frequency: 74 affected / 254 at risk
Study: NCT04198571

Adverse event: Agranulocytosis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 132 at risk

Adverse event: Drug hypersensitivity
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 132 at risk
Study: NCT04198584

Adverse event: Transient Ischemic Attack (TIA)
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 21 at risk
Study: NCT04199793

Adverse event: Rehospitalization due to low INR
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 4 at risk

Adverse event: Rehospitalization
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Pneumothorax requiring chest tube placement; Need for inotropic support during hospitalization.
Frequency: 1 affected / 4 at risk

Adverse event: Ventricular arrhythmia
Serious: yes
Organ System: Cardiac disorders
Notes: Required medications (anti-arrhythmic) adjustments
Frequency: 1 affected / 4 at risk

Adverse event: Device malfunction alarms
Serious: yes
Organ System: Surgical and medical procedures
Notes: Includes controller exchange
Frequency: 1 affected / 4 at risk

Adverse event: Rehospitalization due to low INR
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 4 at risk

Adverse event: Rehospitalization
Serious: yes
Organ System: Surgical and medical procedures
Notes: Surgical wound dehiscence requiring wound vac placement
Frequency: 1 affected / 4 at risk

Adverse event: Rehospitalization
Serious: yes
Organ System: Infections and infestations
Notes: Infections of the genitourinary, gastrointestinal and pulmonary systems.
Frequency: 1 affected / 4 at risk

Adverse event: Right ventricular failure
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 4 at risk

Adverse event: Rehospitalization
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Colitis
Frequency: 1 affected / 4 at risk

Adverse event: Ventricular arrhythmia
Serious: yes
Organ System: Cardiac disorders
Notes: Required medications (anti-arrhythmic) adjustments
Frequency: 1 affected / 4 at risk

Adverse event: Pump/Drive line infection
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 4 at risk

Adverse event: Other systems infections
Serious: yes
Organ System: Infections and infestations
Notes: Not requiring hospitalizations
Frequency: 2 affected / 4 at risk

Adverse event: Haemorrhage
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 4 at risk

Adverse event: Device malfunction alarms
Serious: yes
Organ System: Surgical and medical procedures
Notes: Includes controller exchange
Frequency: 1 affected / 4 at risk
Study: NCT04200248

Adverse event: Iritis
Serious: yes
Organ System: Eye disorders
Frequency: 2 affected / 28 at risk

Adverse event: Vitritis
Serious: yes
Organ System: Eye disorders
Frequency: 2 affected / 28 at risk

Adverse event: Eye pain
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: Eye disorders
Serious: no
Organ System: Eye disorders
Notes: Study eye
Frequency: 13 affected / 28 at risk

Adverse event: Conjunctival haemorrhage
Serious: no
Organ System: Eye disorders
Notes: Study eye
Frequency: 5 affected / 28 at risk

Adverse event: Dry eye
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 4 affected / 28 at risk

Adverse event: Eye irritation
Serious: no
Organ System: Eye disorders
Notes: Study eye
Frequency: 2 affected / 28 at risk

Adverse event: Eye pain
Serious: no
Organ System: Eye disorders
Notes: Study eye
Frequency: 2 affected / 28 at risk

Adverse event: Iritis
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 29 at risk

Adverse event: Vitritis
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 29 at risk

Adverse event: Vision blurred
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 29 at risk

Adverse event: Endophthalmitis
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 29 at risk

Adverse event: Eye disorders
Serious: no
Organ System: Eye disorders
Notes: Study eye
Frequency: 15 affected / 29 at risk

Adverse event: Conjunctival haemorrhage
Serious: no
Organ System: Eye disorders
Notes: Study eye
Frequency: 6 affected / 29 at risk

Adverse event: Dry eye
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 29 at risk

Adverse event: Eye irritation
Serious: no
Organ System: Eye disorders
Notes: Study eye
Frequency: 2 affected / 29 at risk

Adverse event: Iritis
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 29 at risk

Adverse event: Neovascular age-related macular degeneration
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 29 at risk

Adverse event: Eye disorders
Serious: no
Organ System: Eye disorders
Notes: Study eye
Frequency: 8 affected / 29 at risk

Adverse event: Conjunctival haemorrhage
Serious: no
Organ System: Eye disorders
Notes: Study eye
Frequency: 3 affected / 29 at risk

Adverse event: Dry eye
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 29 at risk

Adverse event: Eye irritation
Serious: no
Organ System: Eye disorders
Notes: Study eye
Frequency: 1 affected / 29 at risk
Study: NCT04200352

Adverse event: Cardiopulmonary failure
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 44 at risk

Adverse event: COVID-19
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 44 at risk

Adverse event: Seizure
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 44 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 44 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 44 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 44 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 44 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 3 affected / 44 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 3 affected / 44 at risk

Adverse event: COVID-19
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 44 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 44 at risk

Adverse event: Akathisia
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 44 at risk

Adverse event: Dystonia
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 44 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 44 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 21 affected / 44 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 3 affected / 44 at risk
Study: NCT04200651

Adverse event: Eye pain with movement and lid twitching
Serious: no
Organ System: Eye disorders
Notes: Eye pain with movement and right upper lid twitching that occurred on post-op day 7 and resolved with supplemental topical anti-inflammatory eye drops.
Frequency: 1 affected / 12 at risk

Adverse event: Hyphema and shallow iris
Serious: no
Organ System: Eye disorders
Notes: 2mm hyphema and shallow iris that occurred on post-op day 1 and successfully resolved with topical atropine.
Frequency: 1 affected / 12 at risk

Adverse event: Vitreous floaters
Serious: no
Organ System: Eye disorders
Notes: New-onset small floaters that were noted by the patient on post-op day 30, likely unrelated to the surgery or intervention.
Frequency: 1 affected / 12 at risk
Study: NCT04200911

Adverse event: Altered Mental Status
Serious: yes
Organ System: Nervous system disorders
Notes: Unrelated to study intervention, possible TIA
Frequency: 1 affected / 10 at risk

Adverse event: Intermittent Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Mild and unlikely to be related to intervention
Frequency: 1 affected / 10 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Notes: Moderate and not related to intervention
Frequency: 1 affected / 10 at risk

Adverse event: Urinary retention
Serious: no
Organ System: Renal and urinary disorders
Notes: Mild and unlikely related to intervention
Frequency: 1 affected / 10 at risk

Adverse event: Hyperkalaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Mild and unlikely to be related to intervention
Frequency: 1 affected / 10 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Mild and unlikely to be related to intervention for one subject, possible for the other
Frequency: 1 affected / 10 at risk

Adverse event: Skin infection
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Not related to intervention (kitten scratches)
Frequency: 1 affected / 10 at risk

Adverse event: Oedema peripheral
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Mild for one subject, moderate for the other and unlikely to be related to intervention
Frequency: 2 affected / 10 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Notes: Mild, unlikely to have been related to study intervention
Frequency: 1 affected / 10 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Mild and not likely to be related to intervention
Frequency: 1 affected / 10 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Notes: Mild, one subject was possibly related, the other was not
Frequency: 1 affected / 10 at risk

Adverse event: Urinary incontinence
Serious: no
Organ System: Renal and urinary disorders
Notes: Mild and unlikely related
Frequency: 1 affected / 10 at risk

Adverse event: Micturition urgency
Serious: no
Organ System: Renal and urinary disorders
Notes: Mild and unlikely related
Frequency: 1 affected / 10 at risk

Adverse event: Fall
Serious: no
Organ System: General disorders
Notes: Mild and unlikely related
Frequency: 2 affected / 10 at risk
Study: NCT04201197

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 6 affected / 22 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 22 at risk
Study: NCT04201431

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 12 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 3 affected / 12 at risk

Adverse event: backpain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 12 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 4 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 2 affected / 4 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 1 affected / 5 at risk

Adverse event: backpain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 5 at risk
Study: NCT04201574

Adverse event: Instillation site pain
Serious: no
Organ System: General disorders
Frequency: 9 affected / 46 at risk

Adverse event: Vascular pseudoaneurysm
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 46 at risk

Adverse event: Instillation site pain
Serious: no
Organ System: General disorders
Frequency: 6 affected / 46 at risk

Adverse event: Instillation site pain
Serious: no
Organ System: General disorders
Frequency: 6 affected / 46 at risk
Study: NCT04201639

Adverse event: Small fibre embdeed in superficial epithelium of left cornea
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 32 at risk
Study: NCT04201717

Adverse event: Clavien-Dindo grade III or higher complications
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 10 affected / 157 at risk

Adverse event: Clavien-Dindo graded I-II complications
Serious: no
Organ System: Surgical and medical procedures
Frequency: 13 affected / 157 at risk

Adverse event: Clavien-Dindo grade III or higher complications
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 6 affected / 159 at risk

Adverse event: Clavien-Dindo graded I-II complications
Serious: no
Organ System: Surgical and medical procedures
Frequency: 24 affected / 159 at risk