Study: NCT03310970

Adverse event: Headache
Serious: no
Organ System: General disorders
Notes: Participant reported
Frequency: 1 affected / 22 at risk

Adverse event: Increased Respiratory Rate
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Respiratory Rate Normal Range: 12 - 17 breaths per minutes. Measured by nursing staff.
Frequency: 15 affected / 22 at risk

Adverse event: Increased Heart Rate
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Heart Rate Normal Range: 55 - 100 beats per minutes. Measured by nursing staff
Frequency: 1 affected / 22 at risk

Adverse event: Decreased Heart Rate
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Heart Rate Normal Range: 55 - 100 beats per minute. Measured by nursing staff
Frequency: 6 affected / 22 at risk

Adverse event: Itchy lower back after patch removal
Serious: no
Organ System: General disorders
Notes: Participant reported
Frequency: 1 affected / 22 at risk

Adverse event: Decreased Blood Pressure
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Blood Pressure Normal Range: systolic (90-139 mmHg) diastolic (60-89 mmHg). Blood Pressure was recorded as decreased if either the systolic or diastolic was below normal range defined. Measured by nursing staff.
Frequency: 1 affected / 22 at risk

Adverse event: Blood pressure increased
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Blood Pressure Normal Range: systolic (90-139 mmHg) diastolic (60-89 mmHg). Blood Pressure was recorded as elevated if either the systolic or diastolic was above normal range defined. Measured by nursing staff
Frequency: 2 affected / 22 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Notes: Participant reported
Frequency: 1 affected / 22 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Notes: Participant reported
Frequency: 2 affected / 23 at risk

Adverse event: Increased Respiratory Rate
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Respiratory Rate Normal Range: 12 - 17 breaths per minutes. Measured by nursing staff.
Frequency: 13 affected / 23 at risk

Adverse event: Increased Heart Rate
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Heart Rate Normal Range: 55 - 100 beats per minutes. Measured by nursing staff
Frequency: 3 affected / 23 at risk

Adverse event: Decreased Heart Rate
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Heart Rate Normal Range: 55 - 100 beats per minute. Measured by nursing staff
Frequency: 8 affected / 23 at risk

Adverse event: Decreased Blood Pressure
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Blood Pressure Normal Range: systolic (90-139 mmHg) diastolic (60-89 mmHg). Blood Pressure was recorded as decreased if either the systolic or diastolic was below normal range defined. Measured by nursing staff.
Frequency: 1 affected / 23 at risk

Adverse event: Blood pressure increased
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Blood Pressure Normal Range: systolic (90-139 mmHg) diastolic (60-89 mmHg). Blood Pressure was recorded as elevated if either the systolic or diastolic was above normal range defined. Measured by nursing staff
Frequency: 2 affected / 23 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Notes: Participant reported
Frequency: 1 affected / 23 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Notes: Patient reported
Frequency: 1 affected / 23 at risk

Adverse event: Contact erythema from IV placement
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Participant reported
Frequency: 1 affected / 23 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Notes: Participant reported
Frequency: 2 affected / 23 at risk

Adverse event: Increased Respiratory Rate
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Respiratory Rate Normal Range: 12 - 17 breaths per minutes. Measured by nursing staff.
Frequency: 13 affected / 23 at risk

Adverse event: Increased Heart Rate
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Heart Rate Normal Range: 55 - 100 beats per minutes. Measured by nursing staff
Frequency: 1 affected / 23 at risk

Adverse event: Decreased Heart Rate
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Heart Rate Normal Range: 55 - 100 beats per minute. Measured by nursing staff
Frequency: 3 affected / 23 at risk

Adverse event: Decreased Blood Pressure
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Blood Pressure Normal Range: systolic (90-139 mmHg) diastolic (60-89 mmHg). Blood Pressure was recorded as decreased if either the systolic or diastolic was below normal range defined. Measured by nursing staff.
Frequency: 2 affected / 23 at risk

Adverse event: Blood pressure increased
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Blood Pressure Normal Range: systolic (90-139 mmHg) diastolic (60-89 mmHg). Blood Pressure was recorded as elevated if either the systolic or diastolic was above normal range defined. Measured by nursing staff
Frequency: 3 affected / 23 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Notes: Participant reported
Frequency: 1 affected / 23 at risk

Adverse event: Abnormal Hearing
Serious: no
Organ System: Ear and labyrinth disorders
Notes: Any hearing changes reported by subjects (which were temporary and resolved prior to study end). For example, muffled hearing, ringing in the ears
Frequency: 2 affected / 23 at risk

Adverse event: Drowsiness/Sleepiness
Serious: no
Organ System: General disorders
Notes: Patient reported
Frequency: 1 affected / 23 at risk