Study: NCT02366312

Adverse event: spasm
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Left Quadricep Spasm / non-serious / probably related to study drug
Frequency: 1 affected / 1 at risk

Adverse event: Hypersensitivity
Serious: no
Organ System: General disorders
Notes: right face / non-serious / not related
Frequency: 1 affected / 1 at risk

Adverse event: Spasm
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Both legs / non-serious / probably related
Frequency: 1 affected / 1 at risk

Adverse event: Muscle spasms
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: finger cramping / non-serious / probably related
Frequency: 1 affected / 1 at risk

Adverse event: Facial numbness
Serious: no
Organ System: Nervous system disorders
Notes: Right side / non-serious / probably related
Frequency: 1 affected / 1 at risk

Adverse event: Leg Cramp
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: worsening of leg cramps / non-serious / probably related
Frequency: 1 affected / 1 at risk

Adverse event: Chest discomfort
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: non-serious / not related / possible related
Frequency: 1 affected / 1 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: General disorders
Notes: non-serious / not related
Frequency: 1 affected / 1 at risk

Adverse event: Abdominal discomfort
Serious: no
Organ System: Gastrointestinal disorders
Notes: Non serious / Not related / possibly related
Frequency: 1 affected / 1 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Reproductive system and breast disorders
Notes: non-serious / unlikely related
Frequency: 1 affected / 1 at risk

Adverse event: Loose stool
Serious: no
Organ System: Gastrointestinal disorders
Notes: non-serious, possible related
Frequency: 1 affected / 1 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1 at risk

Adverse event: Left sided muscle ache
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: non-serious, not related
Frequency: 1 affected / 1 at risk

Adverse event: Sacral injury
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: non-serious , not related
Frequency: 1 affected / 1 at risk

Adverse event: High grade Newuorendocrine Carcinoma of head/neck
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Serious but not related to study drug
Frequency: 1 affected / 1 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Notes: Right jaw pain / non serious / possibly related
Frequency: 1 affected / 1 at risk

Adverse event: Ear pain
Serious: no
Organ System: Ear and labyrinth disorders
Notes: Non-serious / unlikely related
Frequency: 1 affected / 1 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: General disorders
Notes: non-serious / unlikely related
Frequency: 1 affected / 1 at risk

Adverse event: Cramping
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Right hand cramping / non-serious / possibly related to study drug
Frequency: 1 affected / 1 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: non-serious / possibly related
Frequency: 1 affected / 1 at risk

Adverse event: Pain
Serious: no
Organ System: Gastrointestinal disorders
Notes: epigastric pain / non-serious / unlikely related
Frequency: 1 affected / 1 at risk

Adverse event: Ageusia
Serious: no
Organ System: General disorders
Notes: non-serious, possibly related
Frequency: 1 affected / 1 at risk

Adverse event: Toes cramping
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: non-serious, possible related
Frequency: 1 affected / 1 at risk

Adverse event: lower extremity pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: both sides, non-serious, possibly related
Frequency: 1 affected / 1 at risk

Adverse event: Right facial pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: non serious, possibly related
Frequency: 1 affected / 1 at risk

Adverse event: Nasopharyn lesion
Serious: no
Organ System: Infections and infestations
Notes: non serious, possibly related
Frequency: 1 affected / 1 at risk

Adverse event: bilateral lower extremities swelling
Serious: no
Organ System: Endocrine disorders
Notes: non-serious , unlikely related
Frequency: 1 affected / 1 at risk