Study: NCT00046930

Adverse event: Bone Marrow Hypocellularity
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 219 at risk

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 160 affected / 219 at risk

Adverse event: Haemolysis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 219 at risk

Adverse event: Leukopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 205 affected / 219 at risk

Adverse event: Lymphopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 219 at risk

Adverse event: Neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 200 affected / 219 at risk

Adverse event: Thrombocytopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 210 affected / 219 at risk

Adverse event: Transfusion: Platelets
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 20 affected / 219 at risk

Adverse event: Transfusion: Peripheral Red Blood Cells
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 18 affected / 219 at risk

Adverse event: Hematologic - Other
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 219 at risk

Adverse event: Conduction Abnormality
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 219 at risk

Adverse event: Dysrhythmia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 219 at risk

Adverse event: Sinus bradycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 219 at risk

Adverse event: Sinus tachycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 4 affected / 219 at risk

Adverse event: Supraventricular Arrhythmia
Serious: yes
Organ System: Cardiac disorders
Frequency: 16 affected / 219 at risk

Adverse event: Arrhythmia - Other
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 219 at risk

Adverse event: Myocardial ischaemia
Serious: yes
Organ System: Cardiac disorders
Frequency: 4 affected / 219 at risk

Adverse event: Cardiac - Left Ventricular Dysfunction
Serious: yes
Organ System: Cardiac disorders
Frequency: 6 affected / 219 at risk

Adverse event: Troponin I increased
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 219 at risk

Adverse event: Troponin T increased
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 219 at risk

Adverse event: Capillary leak syndrome
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 219 at risk

Adverse event: Hypertension
Serious: yes
Organ System: Cardiac disorders
Frequency: 3 affected / 219 at risk

Adverse event: Oedema
Serious: yes
Organ System: Cardiac disorders
Frequency: 6 affected / 219 at risk

Adverse event: Hypotension
Serious: yes
Organ System: Cardiac disorders
Frequency: 16 affected / 219 at risk

Adverse event: Thrombosis/Embolism
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 219 at risk

Adverse event: Cardiac, Other
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 219 at risk

Adverse event: Fatigue
Serious: yes
Organ System: General disorders
Frequency: 38 affected / 219 at risk

Adverse event: Fever w/o neutropenia
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 219 at risk

Adverse event: Rigors/Chills
Serious: yes
Organ System: General disorders
Frequency: 2 affected / 219 at risk

Adverse event: Prolonged Partial Thromboplastin Time
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 219 at risk

Adverse event: PT (INR) Increased
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 219 at risk

Adverse event: Rash/Desquamation
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 10 affected / 219 at risk

Adverse event: Wound, Infectious
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 219 at risk

Adverse event: Neuroendocrine: ADH Secretion Abnormality
Serious: yes
Organ System: Endocrine disorders
Frequency: 1 affected / 219 at risk

Adverse event: Decreased appetite
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 29 affected / 219 at risk

Adverse event: Ascites
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 219 at risk

Adverse event: Colitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 219 at risk

Adverse event: Dehydration
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 219 at risk

Adverse event: Heartburn/Dyspepsia
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 219 at risk

Adverse event: Dysphagia
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 10 affected / 219 at risk

Adverse event: Ulcer, Gastric
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 219 at risk

Adverse event: Nausea
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 18 affected / 219 at risk

Adverse event: Pancreatitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 219 at risk

Adverse event: Stomatitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 19 affected / 219 at risk

Adverse event: Colitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 219 at risk

Adverse event: Vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 6 affected / 219 at risk

Adverse event: Diarrhea w/o Prior Colostomy
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 16 affected / 219 at risk

Adverse event: Diarrhea w/Colostomy
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 219 at risk

Adverse event: GI, Other
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 219 at risk

Adverse event: Hemorrhage, Other
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 12 affected / 219 at risk

Adverse event: Hemorrhage, Upper Respiratory, Nose
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 12 affected / 219 at risk

Adverse event: Hemorrhage, GI, Hematemesis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 219 at risk

Adverse event: Hemorrhage, GU, Hematuria
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 219 at risk

Adverse event: Hemorrhage, Upper Respiratory, Hemoptysis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 219 at risk

Adverse event: Hemorrhage, GI, Melena
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 5 affected / 219 at risk

Adverse event: Petechiae
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 7 affected / 219 at risk

Adverse event: Hemorrhage, GI, Rectum
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 219 at risk

Adverse event: Blood alkaline phosphatase increased
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 219 at risk

Adverse event: Blood bilirubin increased
Serious: yes
Organ System: Investigations
Frequency: 36 affected / 219 at risk

Adverse event: Gamma-glutamyl Transpeptidase (GGT) Increased
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 219 at risk

Adverse event: Hypoalbuminaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 219 at risk

Adverse event: Liver Dysfunction/Failure
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 219 at risk

Adverse event: ALT, SGPT Increased
Serious: yes
Organ System: Investigations
Frequency: 5 affected / 219 at risk

Adverse event: AST, SGOT Increased
Serious: yes
Organ System: Investigations
Frequency: 8 affected / 219 at risk

Adverse event: Infection, Catheter Related
Serious: yes
Organ System: Infections and infestations
Frequency: 5 affected / 219 at risk

Adverse event: Febrile neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 93 affected / 219 at risk

Adverse event: Infection w/ Grade 3 or 4 Neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 119 affected / 219 at risk

Adverse event: Infection w/ Unknown ANC
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 219 at risk

Adverse event: Infection without Neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 8 affected / 219 at risk

Adverse event: Infection, Other
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 219 at risk

Adverse event: Lymphatics, Other
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 219 at risk

Adverse event: Acidosis
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 219 at risk

Adverse event: Alkalosis
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 219 at risk

Adverse event: Amylase increased
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 219 at risk

Adverse event: Bicarbonate, Serum Decreased
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 219 at risk

Adverse event: Hyperglycaemia
Serious: yes
Organ System: Investigations
Frequency: 7 affected / 219 at risk

Adverse event: Hypermagnesaemia
Serious: yes
Organ System: Investigations
Frequency: 3 affected / 219 at risk

Adverse event: Hypernatraemia
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 219 at risk

Adverse event: Hyperuricaemia
Serious: yes
Organ System: Investigations
Frequency: 4 affected / 219 at risk

Adverse event: Hypocalcaemia
Serious: yes
Organ System: Investigations
Frequency: 17 affected / 219 at risk

Adverse event: Hypoglycaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 219 at risk

Adverse event: Hypokalaemia
Serious: yes
Organ System: Investigations
Frequency: 16 affected / 219 at risk

Adverse event: Hypomagnesaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 219 at risk

Adverse event: Hyponatraemia
Serious: yes
Organ System: Investigations
Frequency: 11 affected / 219 at risk

Adverse event: Hypophosphataemia
Serious: yes
Organ System: Investigations
Frequency: 13 affected / 219 at risk

Adverse event: Lipase increased
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 219 at risk

Adverse event: Muscular weakness
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 219 at risk

Adverse event: Ataxia
Serious: yes
Organ System: Investigations
Frequency: 17 affected / 219 at risk

Adverse event: Confusional state
Serious: yes
Organ System: Nervous system disorders
Frequency: 18 affected / 219 at risk

Adverse event: Psychosis (Hallucinations/Delusions)
Serious: yes
Organ System: Nervous system disorders
Frequency: 24 affected / 219 at risk

Adverse event: Somnolence/Depressed Level of Consciousness
Serious: yes
Organ System: Nervous system disorders
Frequency: 8 affected / 219 at risk

Adverse event: Dizziness/Lightheadedness
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 219 at risk

Adverse event: Insomnia
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 219 at risk

Adverse event: Mood Alteration: Anxiety/Agitation
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 219 at risk

Adverse event: Mood Alteration: Depression
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 219 at risk

Adverse event: Neuropathy, Motor
Serious: yes
Organ System: Nervous system disorders
Frequency: 4 affected / 219 at risk

Adverse event: Neuropathy, Sensory
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 219 at risk

Adverse event: Seizure
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 219 at risk

Adverse event: Speech Impairment
Serious: yes
Organ System: Nervous system disorders
Frequency: 4 affected / 219 at risk

Adverse event: Tremor
Serious: yes
Organ System: Nervous system disorders
Frequency: 5 affected / 219 at risk

Adverse event: Vision - Blurred
Serious: yes
Organ System: Eye disorders
Frequency: 2 affected / 219 at risk

Adverse event: Pain, Abdomen
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 8 affected / 219 at risk

Adverse event: Pain, Bone
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 219 at risk

Adverse event: Pain, Headache
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 219 at risk

Adverse event: Pain, Muscle (Myalgia)
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 219 at risk

Adverse event: Pain, Rectum
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 219 at risk

Adverse event: Pain, Other
Serious: yes
Organ System: General disorders
Frequency: 3 affected / 219 at risk

Adverse event: Adult Respiratory Distress Syndrome (ARDS)
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 219 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 22 affected / 219 at risk

Adverse event: Hypoxia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 16 affected / 219 at risk

Adverse event: Pneumonitis/Pulmonary Infiltrates
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 13 affected / 219 at risk

Adverse event: Voice changes/Dysarthria
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 219 at risk

Adverse event: Pulmonary, Other
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 219 at risk

Adverse event: Incontinence, Urinary
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 2 affected / 219 at risk

Adverse event: Proteinuria
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 219 at risk

Adverse event: Renal failure
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 4 affected / 219 at risk

Adverse event: Renal, Other
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 2 affected / 219 at risk

Adverse event: Tumour lysis syndrome
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 6 affected / 219 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 210 affected / 219 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 171 affected / 219 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 134 affected / 219 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 164 affected / 219 at risk

Adverse event: Oedema
Serious: no
Organ System: Cardiac disorders
Frequency: 34 affected / 219 at risk

Adverse event: Hypotension
Serious: no
Organ System: Cardiac disorders
Frequency: 6 affected / 219 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 77 affected / 219 at risk

Adverse event: Fever w/o neutropenia
Serious: no
Organ System: General disorders
Frequency: 8 affected / 219 at risk

Adverse event: Rigors/Chills
Serious: no
Organ System: General disorders
Frequency: 29 affected / 219 at risk

Adverse event: Hyperhidrosis
Serious: no
Organ System: General disorders
Frequency: 8 affected / 219 at risk

Adverse event: Weight decreased
Serious: no
Organ System: General disorders
Frequency: 15 affected / 219 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 63 affected / 219 at risk

Adverse event: Flushing
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 4 affected / 219 at risk

Adverse event: Pruritis/Itching
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 12 affected / 219 at risk

Adverse event: Rash/Desquamation
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 48 affected / 219 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 52 affected / 219 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 25 affected / 219 at risk

Adverse event: Heartburn/Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 15 affected / 219 at risk

Adverse event: Dysphagia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 17 affected / 219 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 89 affected / 219 at risk

Adverse event: Stomatitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 68 affected / 219 at risk

Adverse event: Taste disorder
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 21 affected / 219 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 56 affected / 219 at risk

Adverse event: Diarrhea w/o Prior Colostomy
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 107 affected / 219 at risk

Adverse event: Epistaxis
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 13 affected / 219 at risk

Adverse event: Petechiae
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 21 affected / 219 at risk

Adverse event: Blood alkaline phosphatase increased
Serious: no
Organ System: Investigations
Frequency: 101 affected / 219 at risk

Adverse event: Blood bilirubin increased
Serious: no
Organ System: Investigations
Frequency: 117 affected / 219 at risk

Adverse event: Hypoalbuminaemia
Serious: no
Organ System: Investigations
Frequency: 13 affected / 219 at risk

Adverse event: AST, SGOT Increased
Serious: no
Organ System: Investigations
Frequency: 97 affected / 219 at risk

Adverse event: ALT, SGPT Increased
Serious: no
Organ System: Investigations
Frequency: 75 affected / 219 at risk

Adverse event: Hyperglycaemia
Serious: no
Organ System: Investigations
Frequency: 18 affected / 219 at risk

Adverse event: Hypermagnesaemia
Serious: no
Organ System: Investigations
Frequency: 35 affected / 219 at risk

Adverse event: Hypocalcaemia
Serious: no
Organ System: Investigations
Frequency: 23 affected / 219 at risk

Adverse event: Hypomagnesaemia
Serious: no
Organ System: Investigations
Frequency: 92 affected / 219 at risk

Adverse event: Hyponatraemia
Serious: no
Organ System: Investigations
Frequency: 20 affected / 219 at risk

Adverse event: Ataxia
Serious: no
Organ System: Nervous system disorders
Frequency: 11 affected / 219 at risk

Adverse event: Confusional state
Serious: no
Organ System: Nervous system disorders
Frequency: 17 affected / 219 at risk

Adverse event: Dizziness/Lightheadedness
Serious: no
Organ System: Nervous system disorders
Frequency: 19 affected / 219 at risk

Adverse event: Tremor
Serious: no
Organ System: Nervous system disorders
Frequency: 29 affected / 219 at risk

Adverse event: Pain, Abdomen
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 28 affected / 219 at risk

Adverse event: Pain, Joint (Arthralgia)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 9 affected / 219 at risk

Adverse event: Pain, Bone
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 7 affected / 219 at risk

Adverse event: Pain, Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 22 affected / 219 at risk

Adverse event: Pain, Muscle (Myalgia)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 10 affected / 219 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 16 affected / 219 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 18 affected / 219 at risk

Adverse event: Blood creatinine increased
Serious: no
Organ System: Investigations
Frequency: 78 affected / 219 at risk

Adverse event: Bone Marrow Hypocellularity
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 222 at risk

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 152 affected / 222 at risk

Adverse event: Leukopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 211 affected / 222 at risk

Adverse event: Lymphopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 5 affected / 222 at risk

Adverse event: Neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 202 affected / 222 at risk

Adverse event: Thrombocytopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 214 affected / 222 at risk

Adverse event: Transfusion: Platelets
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 23 affected / 222 at risk

Adverse event: Transfusion: Peripheral Red Blood Cells
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 18 affected / 222 at risk

Adverse event: Hematologic - Other
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 222 at risk

Adverse event: Sinus bradycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 222 at risk

Adverse event: Sinus tachycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 5 affected / 222 at risk

Adverse event: Supraventricular Arrhythmia
Serious: yes
Organ System: Cardiac disorders
Frequency: 8 affected / 222 at risk

Adverse event: Ventricular arrhythmia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 222 at risk

Adverse event: Arrhythmia - Other
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 222 at risk

Adverse event: Myocardial ischaemia
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 222 at risk

Adverse event: Cardiac - Left Ventricular Dysfunction
Serious: yes
Organ System: Cardiac disorders
Frequency: 8 affected / 222 at risk

Adverse event: Troponin I increased
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 222 at risk

Adverse event: Capillary leak syndrome
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 222 at risk

Adverse event: Hypertension
Serious: yes
Organ System: Cardiac disorders
Frequency: 7 affected / 222 at risk

Adverse event: Oedema
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 222 at risk

Adverse event: Hypotension
Serious: yes
Organ System: Cardiac disorders
Frequency: 9 affected / 222 at risk

Adverse event: Thrombosis/Embolism
Serious: yes
Organ System: Vascular disorders
Frequency: 2 affected / 222 at risk

Adverse event: Cardiac, Other
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 222 at risk

Adverse event: Fatigue
Serious: yes
Organ System: General disorders
Frequency: 22 affected / 222 at risk

Adverse event: Rigors/Chills
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 222 at risk

Adverse event: Constitutional, Other
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 222 at risk

Adverse event: Disseminated intravascular coagulation
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 222 at risk

Adverse event: Blood fibrinogen decreased
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 222 at risk

Adverse event: Prolonged Partial Thromboplastin Time
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 222 at risk

Adverse event: PT (INR) Increased
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 222 at risk

Adverse event: Rash/Desquamation
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 4 affected / 222 at risk

Adverse event: Wound, Infectious
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 222 at risk

Adverse event: Decreased appetite
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 20 affected / 222 at risk

Adverse event: Colitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 222 at risk

Adverse event: Constipation
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 222 at risk

Adverse event: Dehydration
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 222 at risk

Adverse event: Heartburn/Dyspepsia
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 222 at risk

Adverse event: Dysphagia
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 222 at risk

Adverse event: Nausea
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 12 affected / 222 at risk

Adverse event: Stomatitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 11 affected / 222 at risk

Adverse event: Colitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 222 at risk

Adverse event: Vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 222 at risk

Adverse event: Diarrhea w/o Prior Colostomy
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 13 affected / 222 at risk

Adverse event: GI, Other
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 222 at risk

Adverse event: Hemorrhage, Other
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 3 affected / 222 at risk

Adverse event: Hemorrhage, Upper Respiratory, Nose
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 13 affected / 222 at risk

Adverse event: Hemorrhage, GI, Hematemesis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 222 at risk

Adverse event: Hemorrhage, GU, Hematuria
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 222 at risk

Adverse event: Hemorrhage, Upper Respiratory, Hemoptysis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 222 at risk

Adverse event: Hemorrhage Associated with Surgery
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 222 at risk

Adverse event: Hemorrhage, GI, Melena
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 4 affected / 222 at risk

Adverse event: Petechiae
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 13 affected / 222 at risk

Adverse event: Hemorrhage, GI, Rectum
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 222 at risk

Adverse event: Blood alkaline phosphatase increased
Serious: yes
Organ System: Investigations
Frequency: 4 affected / 222 at risk

Adverse event: Blood bilirubin increased
Serious: yes
Organ System: Investigations
Frequency: 31 affected / 222 at risk

Adverse event: Hypoalbuminaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 222 at risk

Adverse event: ALT, SGPT Increased
Serious: yes
Organ System: Investigations
Frequency: 8 affected / 222 at risk

Adverse event: AST, SGOT Increased
Serious: yes
Organ System: Investigations
Frequency: 11 affected / 222 at risk

Adverse event: Infection, Catheter Related
Serious: yes
Organ System: Infections and infestations
Frequency: 8 affected / 222 at risk

Adverse event: Febrile neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 82 affected / 222 at risk

Adverse event: Infection w/ Grade 3 or 4 Neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 121 affected / 222 at risk

Adverse event: Infection w/ Unknown ANC
Serious: yes
Organ System: Infections and infestations
Frequency: 3 affected / 222 at risk

Adverse event: Infection without Neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 7 affected / 222 at risk

Adverse event: Infection, Other
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 222 at risk

Adverse event: Acidosis
Serious: yes
Organ System: Investigations
Frequency: 3 affected / 222 at risk

Adverse event: Bicarbonate, Serum Decreased
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 222 at risk

Adverse event: Hyperglycaemia
Serious: yes
Organ System: Investigations
Frequency: 3 affected / 222 at risk

Adverse event: Hyperkalaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 222 at risk

Adverse event: Hypermagnesaemia
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 222 at risk

Adverse event: Hyperuricaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 222 at risk

Adverse event: Hypocalcaemia
Serious: yes
Organ System: Investigations
Frequency: 7 affected / 222 at risk

Adverse event: Hypokalaemia
Serious: yes
Organ System: Investigations
Frequency: 12 affected / 222 at risk

Adverse event: Hypomagnesaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 222 at risk

Adverse event: Hyponatraemia
Serious: yes
Organ System: Investigations
Frequency: 3 affected / 222 at risk

Adverse event: Hypophosphataemia
Serious: yes
Organ System: Investigations
Frequency: 4 affected / 222 at risk

Adverse event: Ataxia
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 222 at risk

Adverse event: Cerebrovascular Ischemia
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 222 at risk

Adverse event: Confusional state
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 222 at risk

Adverse event: Psychosis (Hallucinations/Delusions)
Serious: yes
Organ System: Nervous system disorders
Frequency: 10 affected / 222 at risk

Adverse event: Somnolence/Depressed Level of Consciousness
Serious: yes
Organ System: Nervous system disorders
Frequency: 4 affected / 222 at risk

Adverse event: Memory impairment
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 222 at risk

Adverse event: Mood Alteration: Depression
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 222 at risk

Adverse event: Neuropathy, Motor
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 222 at risk

Adverse event: Seizure
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 222 at risk

Adverse event: Conjunctivitis
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 222 at risk

Adverse event: Vision - Blurred
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 222 at risk

Adverse event: Pain, Abdomen
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 222 at risk

Adverse event: Pain, Joint (Arthralgia)
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 222 at risk

Adverse event: Pain, Bone
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 222 at risk

Adverse event: Pain, Headache
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 222 at risk

Adverse event: Pain, Muscle (Myalgia)
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 222 at risk

Adverse event: Pain, Pleura
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 222 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 21 affected / 222 at risk

Adverse event: Hypoxia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 12 affected / 222 at risk

Adverse event: Pneumonitis/Pulmonary Infiltrates
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 11 affected / 222 at risk

Adverse event: Voice changes/Dysarthria
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 222 at risk

Adverse event: Pulmonary, Other
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 222 at risk

Adverse event: Renal, Other - Dysuria
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 222 at risk

Adverse event: Renal failure
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 4 affected / 222 at risk

Adverse event: Urinary Frequency/Urgency
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 222 at risk

Adverse event: Renal, Other
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 222 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 215 affected / 222 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 172 affected / 222 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 137 affected / 222 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 183 affected / 222 at risk

Adverse event: Oedema
Serious: no
Organ System: Cardiac disorders
Frequency: 46 affected / 222 at risk

Adverse event: Hypotension
Serious: no
Organ System: Cardiac disorders
Frequency: 5 affected / 222 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 79 affected / 222 at risk

Adverse event: Fever w/o neutropenia
Serious: no
Organ System: General disorders
Frequency: 14 affected / 222 at risk

Adverse event: Rigors/Chills
Serious: no
Organ System: General disorders
Frequency: 31 affected / 222 at risk

Adverse event: Hyperhidrosis
Serious: no
Organ System: General disorders
Frequency: 15 affected / 222 at risk

Adverse event: Weight decreased
Serious: no
Organ System: General disorders
Frequency: 9 affected / 222 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 70 affected / 222 at risk

Adverse event: Flushing
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 222 at risk

Adverse event: Pruritis/Itching
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 11 affected / 222 at risk

Adverse event: Rash/Desquamation
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 43 affected / 222 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 41 affected / 222 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 22 affected / 222 at risk

Adverse event: Heartburn/Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 13 affected / 222 at risk

Adverse event: Dysphagia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 10 affected / 222 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 88 affected / 222 at risk

Adverse event: Stomatitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 61 affected / 222 at risk

Adverse event: Taste disorder
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 16 affected / 222 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 39 affected / 222 at risk

Adverse event: Diarrhea w/o Prior Colostomy
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 92 affected / 222 at risk

Adverse event: Epistaxis
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 18 affected / 222 at risk

Adverse event: Petechiae
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 16 affected / 222 at risk

Adverse event: Blood alkaline phosphatase increased
Serious: no
Organ System: Investigations
Frequency: 95 affected / 222 at risk

Adverse event: Blood bilirubin increased
Serious: no
Organ System: Investigations
Frequency: 113 affected / 222 at risk

Adverse event: Hypoalbuminaemia
Serious: no
Organ System: Investigations
Frequency: 11 affected / 222 at risk

Adverse event: AST, SGOT Increased
Serious: no
Organ System: Investigations
Frequency: 84 affected / 222 at risk

Adverse event: ALT, SGPT Increased
Serious: no
Organ System: Investigations
Frequency: 92 affected / 222 at risk

Adverse event: Hyperglycaemia
Serious: no
Organ System: Investigations
Frequency: 11 affected / 222 at risk

Adverse event: Hypermagnesaemia
Serious: no
Organ System: Investigations
Frequency: 22 affected / 222 at risk

Adverse event: Hypocalcaemia
Serious: no
Organ System: Investigations
Frequency: 17 affected / 222 at risk

Adverse event: Hypomagnesaemia
Serious: no
Organ System: Investigations
Frequency: 82 affected / 222 at risk

Adverse event: Hyponatraemia
Serious: no
Organ System: Investigations
Frequency: 16 affected / 222 at risk

Adverse event: Ataxia
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 222 at risk

Adverse event: Confusional state
Serious: no
Organ System: Nervous system disorders
Frequency: 8 affected / 222 at risk

Adverse event: Dizziness/Lightheadedness
Serious: no
Organ System: Nervous system disorders
Frequency: 8 affected / 222 at risk

Adverse event: Tremor
Serious: no
Organ System: Nervous system disorders
Frequency: 12 affected / 222 at risk

Adverse event: Pain, Abdomen
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 17 affected / 222 at risk

Adverse event: Pain, Joint (Arthralgia)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 222 at risk

Adverse event: Pain, Bone
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 222 at risk

Adverse event: Pain, Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 30 affected / 222 at risk

Adverse event: Pain, Muscle (Myalgia)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 9 affected / 222 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 19 affected / 222 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 13 affected / 222 at risk

Adverse event: Blood creatinine increased
Serious: no
Organ System: Investigations
Frequency: 59 affected / 222 at risk

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 94 affected / 180 at risk

Adverse event: Leukopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 167 affected / 180 at risk

Adverse event: Lymphopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 180 at risk

Adverse event: Neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 153 affected / 180 at risk

Adverse event: Thrombocytopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 169 affected / 180 at risk

Adverse event: Transfusion: Platelets
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 20 affected / 180 at risk

Adverse event: Transfusion: Peripheral Red Blood Cells
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 15 affected / 180 at risk

Adverse event: Sinus tachycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 180 at risk

Adverse event: Supraventricular Arrhythmia
Serious: yes
Organ System: Cardiac disorders
Frequency: 4 affected / 180 at risk

Adverse event: Ventricular arrhythmia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 180 at risk

Adverse event: Myocardial ischaemia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 180 at risk

Adverse event: Cardiac - Left Ventricular Dysfunction
Serious: yes
Organ System: Cardiac disorders
Frequency: 3 affected / 180 at risk

Adverse event: Troponin I increased
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 180 at risk

Adverse event: Hypotension
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 180 at risk

Adverse event: Cardiac, Other
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 180 at risk

Adverse event: Fatigue
Serious: yes
Organ System: General disorders
Frequency: 8 affected / 180 at risk

Adverse event: Fever w/o neutropenia
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 180 at risk

Adverse event: Thrombotic microangiopathy
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 180 at risk

Adverse event: Pruritis/itching
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 180 at risk

Adverse event: Rash/Desquamation
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 180 at risk

Adverse event: Wound, Infectious
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 180 at risk

Adverse event: Decreased appetite
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 180 at risk

Adverse event: Colitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 180 at risk

Adverse event: Dehydration
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 180 at risk

Adverse event: Dysphagia
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 180 at risk

Adverse event: Nausea
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 180 at risk

Adverse event: Stomatitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 180 at risk

Adverse event: Colitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 180 at risk

Adverse event: Diarrhea w/o Prior Colostomy
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 180 at risk

Adverse event: Hemorrhage, Other
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 4 affected / 180 at risk

Adverse event: Hemorrhage, Upper Respiratory, Nose
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 180 at risk

Adverse event: Hemorrhage, GI, Hematemesis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 180 at risk

Adverse event: Hemorrhage, GU, Hematuria
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 180 at risk

Adverse event: Petechiae
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 8 affected / 180 at risk

Adverse event: Blood alkaline phosphatase increased
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 180 at risk

Adverse event: Blood bilirubin increased
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 180 at risk

Adverse event: Hypoalbuminaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 180 at risk

Adverse event: Hemorrhage, GU, Vagina
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 180 at risk

Adverse event: ALT, SGPT Increased
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 180 at risk

Adverse event: AST, SGOT Increased
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 180 at risk

Adverse event: Infection, Catheter Related
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 180 at risk

Adverse event: Febrile neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 42 affected / 180 at risk

Adverse event: Infection w/ Grade 3 or 4 Neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 57 affected / 180 at risk

Adverse event: Infection w/ Unknown ANC
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 180 at risk

Adverse event: Infection without Neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 17 affected / 180 at risk

Adverse event: Acidosis
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 180 at risk

Adverse event: Hyperglycaemia
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 180 at risk

Adverse event: Hypermagnesaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 180 at risk

Adverse event: Hypokalaemia
Serious: yes
Organ System: Investigations
Frequency: 3 affected / 180 at risk

Adverse event: Hyponatraemia
Serious: yes
Organ System: Investigations
Frequency: 3 affected / 180 at risk

Adverse event: Hypophosphataemia
Serious: yes
Organ System: Investigations
Frequency: 3 affected / 180 at risk

Adverse event: Ataxia
Serious: yes
Organ System: Investigations
Frequency: 5 affected / 180 at risk

Adverse event: Confusional state
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 180 at risk

Adverse event: Psychosis (Hallucinations/Delusions)
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 180 at risk

Adverse event: Somnolence/Depressed Level of Consciousness
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 180 at risk

Adverse event: Dizziness/Lightheadedness
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 180 at risk

Adverse event: Mood Alteration: Anxiety/Agitation
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 180 at risk

Adverse event: Neuropathy, Motor
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 180 at risk

Adverse event: Neuropathy, Sensory
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 180 at risk

Adverse event: Syncope
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 180 at risk

Adverse event: Neurologic - Other
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 180 at risk

Adverse event: Nystagmus
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 180 at risk

Adverse event: Pain, Abdomen
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 180 at risk

Adverse event: Pain, Bone
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 180 at risk

Adverse event: Pain, Headache
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 180 at risk

Adverse event: Pain, Muscle (Myalgia)
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 180 at risk

Adverse event: Pain, Rectum
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 180 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 180 at risk

Adverse event: Hypoxia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 180 at risk

Adverse event: Pneumonitis/Pulmonary Infiltrates
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 180 at risk

Adverse event: Renal failure
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 180 at risk

Adverse event: Urinary retention
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 180 at risk

Adverse event: Keratitis
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 180 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 179 affected / 180 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 152 affected / 180 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 116 affected / 180 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 168 affected / 180 at risk

Adverse event: Oedema
Serious: no
Organ System: Cardiac disorders
Frequency: 17 affected / 180 at risk

Adverse event: Hypotension
Serious: no
Organ System: Cardiac disorders
Frequency: 6 affected / 180 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 78 affected / 180 at risk

Adverse event: Fever w/o neutropenia
Serious: no
Organ System: General disorders
Frequency: 12 affected / 180 at risk

Adverse event: Rigors/Chills
Serious: no
Organ System: General disorders
Frequency: 22 affected / 180 at risk

Adverse event: Hyperhidrosis
Serious: no
Organ System: General disorders
Frequency: 4 affected / 180 at risk

Adverse event: Weight decreased
Serious: no
Organ System: General disorders
Frequency: 10 affected / 180 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 74 affected / 180 at risk

Adverse event: Flushing
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 5 affected / 180 at risk

Adverse event: Pruritis/Itching
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 5 affected / 180 at risk

Adverse event: Rash/Desquamation
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 31 affected / 180 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 29 affected / 180 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 11 affected / 180 at risk

Adverse event: Heartburn/Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 180 at risk

Adverse event: Dysphagia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 180 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 41 affected / 180 at risk

Adverse event: Stomatitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 29 affected / 180 at risk

Adverse event: Taste disorder
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 180 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 16 affected / 180 at risk

Adverse event: Diarrhea w/o Prior Colostomy
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 37 affected / 180 at risk

Adverse event: Epistaxis
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 6 affected / 180 at risk

Adverse event: Petechiae
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 10 affected / 180 at risk

Adverse event: Blood alkaline phosphatase increased
Serious: no
Organ System: Investigations
Frequency: 57 affected / 180 at risk

Adverse event: Blood bilirubin increased
Serious: no
Organ System: Investigations
Frequency: 61 affected / 180 at risk

Adverse event: Hypoalbuminaemia
Serious: no
Organ System: Investigations
Frequency: 6 affected / 180 at risk

Adverse event: AST, SGOT Increased
Serious: no
Organ System: Investigations
Frequency: 42 affected / 180 at risk

Adverse event: ALT, SGPT Increased
Serious: no
Organ System: Investigations
Frequency: 47 affected / 180 at risk

Adverse event: Hyperglycaemia
Serious: no
Organ System: Investigations
Frequency: 11 affected / 180 at risk

Adverse event: Hypermagnesaemia
Serious: no
Organ System: Investigations
Frequency: 14 affected / 180 at risk

Adverse event: Hypocalcaemia
Serious: no
Organ System: Investigations
Frequency: 9 affected / 180 at risk

Adverse event: Hypomagnesaemia
Serious: no
Organ System: Investigations
Frequency: 56 affected / 180 at risk

Adverse event: Hyponatraemia
Serious: no
Organ System: Investigations
Frequency: 6 affected / 180 at risk

Adverse event: Ataxia
Serious: no
Organ System: Nervous system disorders
Frequency: 6 affected / 180 at risk

Adverse event: Confusional state
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 180 at risk

Adverse event: Dizziness/Lightheadedness
Serious: no
Organ System: Nervous system disorders
Frequency: 12 affected / 180 at risk

Adverse event: Tremor
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 180 at risk

Adverse event: Pain, Abdomen
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 10 affected / 180 at risk

Adverse event: Pain, Joint (Arthralgia)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 7 affected / 180 at risk

Adverse event: Pain, Bone
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 8 affected / 180 at risk

Adverse event: Pain, Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 14 affected / 180 at risk

Adverse event: Pain, Muscle (Myalgia)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 11 affected / 180 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 6 affected / 180 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 7 affected / 180 at risk

Adverse event: Blood creatinine increased
Serious: no
Organ System: Investigations
Frequency: 23 affected / 180 at risk

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 32 affected / 59 at risk

Adverse event: Leukopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 58 affected / 59 at risk

Adverse event: Lymphopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 59 at risk

Adverse event: Neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 48 affected / 59 at risk

Adverse event: Thrombocytopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 48 affected / 59 at risk

Adverse event: Transfusion: Platelets
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 5 affected / 59 at risk

Adverse event: Transfusion: Peripheral Red Blood Cells
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 4 affected / 59 at risk

Adverse event: Myocardial ischaemia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 59 at risk

Adverse event: Cardiac - Left Ventricular Dysfunction
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 59 at risk

Adverse event: Hypertension
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 59 at risk

Adverse event: Hypotension
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 59 at risk

Adverse event: Thrombosis/Embolism
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 59 at risk

Adverse event: Fatigue
Serious: yes
Organ System: General disorders
Frequency: 4 affected / 59 at risk

Adverse event: Wound, Infectious
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 59 at risk

Adverse event: Decreased appetite
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 59 at risk

Adverse event: Colitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 59 at risk

Adverse event: Nausea
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 59 at risk

Adverse event: Stomatitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 59 at risk

Adverse event: Diarrhea w/o Prior Colostomy
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 59 at risk

Adverse event: Hemorrhage, Upper Respiratory, Nose
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 59 at risk

Adverse event: Blood bilirubin increased
Serious: yes
Organ System: Investigations
Frequency: 4 affected / 59 at risk

Adverse event: Infection, Catheter Related
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 59 at risk

Adverse event: Febrile neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 12 affected / 59 at risk

Adverse event: Infection w/ Grade 3 or 4 Neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 29 affected / 59 at risk

Adverse event: Infection without Neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 3 affected / 59 at risk

Adverse event: Hypokalaemia
Serious: yes
Organ System: Investigations
Frequency: 6 affected / 59 at risk

Adverse event: Hyponatraemia
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 59 at risk

Adverse event: Hypophosphataemia
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 59 at risk

Adverse event: Muscular weakness
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 59 at risk

Adverse event: Ataxia
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 59 at risk

Adverse event: Confusional state
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 59 at risk

Adverse event: Neuropathy, Motor
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 59 at risk

Adverse event: Pyramidal Tract Dysfunction
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 59 at risk

Adverse event: Syncope
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 59 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 59 at risk

Adverse event: Hypoxia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 59 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 59 affected / 59 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 56 affected / 59 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 49 affected / 59 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 57 affected / 59 at risk

Adverse event: Oedema
Serious: no
Organ System: Cardiac disorders
Frequency: 4 affected / 59 at risk

Adverse event: Hypotension
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 59 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 18 affected / 59 at risk

Adverse event: Fever w/o neutropenia
Serious: no
Organ System: General disorders
Frequency: 4 affected / 59 at risk

Adverse event: Rigors/Chills
Serious: no
Organ System: General disorders
Frequency: 6 affected / 59 at risk

Adverse event: Hyperhidrosis
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Weight decreased
Serious: no
Organ System: General disorders
Frequency: 4 affected / 59 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 25 affected / 59 at risk

Adverse event: Flushing
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 5 affected / 59 at risk

Adverse event: Pruritis/Itching
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 59 at risk

Adverse event: Rash/Desquamation
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 12 affected / 59 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 14 affected / 59 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 59 at risk

Adverse event: Heartburn/Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 59 at risk

Adverse event: Dysphagia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 59 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 17 affected / 59 at risk

Adverse event: Stomatitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 14 affected / 59 at risk

Adverse event: Taste disorder
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 59 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 9 affected / 59 at risk

Adverse event: Diarrhea w/o Prior Colostomy
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 20 affected / 59 at risk

Adverse event: Epistaxis
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 4 affected / 59 at risk

Adverse event: Petechiae
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 4 affected / 59 at risk

Adverse event: Blood alkaline phosphatase increased
Serious: no
Organ System: Investigations
Frequency: 17 affected / 59 at risk

Adverse event: Blood bilirubin increased
Serious: no
Organ System: Investigations
Frequency: 12 affected / 59 at risk

Adverse event: Hypoalbuminaemia
Serious: no
Organ System: Investigations
Frequency: 4 affected / 59 at risk

Adverse event: AST, SGOT Increased
Serious: no
Organ System: Investigations
Frequency: 19 affected / 59 at risk

Adverse event: ALT, SGPT Increased
Serious: no
Organ System: Investigations
Frequency: 20 affected / 59 at risk

Adverse event: Hyperglycaemia
Serious: no
Organ System: Investigations
Frequency: 6 affected / 59 at risk

Adverse event: Hypermagnesaemia
Serious: no
Organ System: Investigations
Frequency: 4 affected / 59 at risk

Adverse event: Hypocalcaemia
Serious: no
Organ System: Investigations
Frequency: 5 affected / 59 at risk

Adverse event: Hypomagnesaemia
Serious: no
Organ System: Investigations
Frequency: 28 affected / 59 at risk

Adverse event: Hyponatraemia
Serious: no
Organ System: Investigations
Frequency: 3 affected / 59 at risk

Adverse event: Ataxia
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 59 at risk

Adverse event: Confusional state
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 59 at risk

Adverse event: Dizziness/Lightheadedness
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 59 at risk

Adverse event: Tremor
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 59 at risk

Adverse event: Pain, Abdomen
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 59 at risk

Adverse event: Pain, Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 59 at risk

Adverse event: Pain, Muscle (Myalgia)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 59 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 59 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 59 at risk

Adverse event: Blood creatinine increased
Serious: no
Organ System: Investigations
Frequency: 10 affected / 59 at risk

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 37 affected / 70 at risk

Adverse event: Leukopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 66 affected / 70 at risk

Adverse event: Lymphopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 70 at risk

Adverse event: Neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 61 affected / 70 at risk

Adverse event: Thrombocytopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 61 affected / 70 at risk

Adverse event: Transfusion: Platelets
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 10 affected / 70 at risk

Adverse event: Transfusion: Peripheral Red Blood Cells
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 8 affected / 70 at risk

Adverse event: Cardiac - Left Ventricular Dysfunction
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 70 at risk

Adverse event: Hypotension
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 70 at risk

Adverse event: Thrombosis/Embolism
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 70 at risk

Adverse event: Fatigue
Serious: yes
Organ System: General disorders
Frequency: 2 affected / 70 at risk

Adverse event: Rash/Desquamation
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 70 at risk

Adverse event: Decreased appetite
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 70 at risk

Adverse event: Colitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 70 at risk

Adverse event: Dehydration
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 70 at risk

Adverse event: Nausea
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 70 at risk

Adverse event: Stomatitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 70 at risk

Adverse event: Diarrhea w/o Prior Colostomy
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 70 at risk

Adverse event: Hemorrhage, Other
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 3 affected / 70 at risk

Adverse event: Hemorrhage, Upper Respiratory, Nose
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 70 at risk

Adverse event: Hemorrhage, GI, Hematemesis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 70 at risk

Adverse event: Hemorrhage, GI, Melena
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 70 at risk

Adverse event: Petechiae
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 4 affected / 70 at risk

Adverse event: Blood bilirubin increased
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 70 at risk

Adverse event: ALT, SGPT Increased
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 70 at risk

Adverse event: AST, SGOT Increased
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 70 at risk

Adverse event: Hepatic, Other
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 70 at risk

Adverse event: Infection, Catheter Related
Serious: yes
Organ System: Infections and infestations
Frequency: 3 affected / 70 at risk

Adverse event: Febrile neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 15 affected / 70 at risk

Adverse event: Infection w/ Grade 3 or 4 Neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 26 affected / 70 at risk

Adverse event: Infection without Neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 4 affected / 70 at risk

Adverse event: Hypokalaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 70 at risk

Adverse event: Hyponatraemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 70 at risk

Adverse event: Hypophosphataemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 70 at risk

Adverse event: Dizziness/Lightheadedness
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 70 at risk

Adverse event: Neuropathy, Motor
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 70 at risk

Adverse event: Pain, Joint (Arthralgia)
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 70 at risk

Adverse event: Pain, Bone
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 70 at risk

Adverse event: Pain, Muscle (Myalgia)
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 70 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 70 at risk

Adverse event: Pneumonitis/Pulmonary Infiltrates
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 70 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 70 affected / 70 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 69 affected / 70 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 57 affected / 70 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 67 affected / 70 at risk

Adverse event: Oedema
Serious: no
Organ System: Cardiac disorders
Frequency: 7 affected / 70 at risk

Adverse event: Hypotension
Serious: no
Organ System: Cardiac disorders
Frequency: 4 affected / 70 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 26 affected / 70 at risk

Adverse event: Rigors/Chills
Serious: no
Organ System: General disorders
Frequency: 14 affected / 70 at risk

Adverse event: Hyperhidrosis
Serious: no
Organ System: General disorders
Frequency: 3 affected / 70 at risk

Adverse event: Weight decreased
Serious: no
Organ System: General disorders
Frequency: 3 affected / 70 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 26 affected / 70 at risk

Adverse event: Flushing
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 70 at risk

Adverse event: Pruritis/Itching
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 70 at risk

Adverse event: Rash/Desquamation
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 9 affected / 70 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 11 affected / 70 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 8 affected / 70 at risk

Adverse event: Dysphagia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 70 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 24 affected / 70 at risk

Adverse event: Stomatitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 9 affected / 70 at risk

Adverse event: Taste disorder
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 70 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 8 affected / 70 at risk

Adverse event: Diarrhea w/o Prior Colostomy
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 17 affected / 70 at risk

Adverse event: Epistaxis
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 70 at risk

Adverse event: Petechiae
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 70 at risk

Adverse event: Blood alkaline phosphatase increased
Serious: no
Organ System: Investigations
Frequency: 15 affected / 70 at risk

Adverse event: Blood bilirubin increased
Serious: no
Organ System: Investigations
Frequency: 14 affected / 70 at risk

Adverse event: Hypoalbuminaemia
Serious: no
Organ System: Investigations
Frequency: 3 affected / 70 at risk

Adverse event: AST, SGOT Increased
Serious: no
Organ System: Investigations
Frequency: 7 affected / 70 at risk

Adverse event: ALT, SGPT Increased
Serious: no
Organ System: Investigations
Frequency: 12 affected / 70 at risk

Adverse event: Hyperglycaemia
Serious: no
Organ System: Investigations
Frequency: 4 affected / 70 at risk

Adverse event: Hypermagnesaemia
Serious: no
Organ System: Investigations
Frequency: 3 affected / 70 at risk

Adverse event: Hypocalcaemia
Serious: no
Organ System: Investigations
Frequency: 3 affected / 70 at risk

Adverse event: Hypomagnesaemia
Serious: no
Organ System: Investigations
Frequency: 22 affected / 70 at risk

Adverse event: Hyponatraemia
Serious: no
Organ System: Investigations
Frequency: 1 affected / 70 at risk

Adverse event: Confusional state
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 70 at risk

Adverse event: Dizziness/Lightheadedness
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 70 at risk

Adverse event: Tremor
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 70 at risk

Adverse event: Pain, Abdomen
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 70 at risk

Adverse event: Pain, Joint (Arthralgia)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 6 affected / 70 at risk

Adverse event: Pain, Bone
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 4 affected / 70 at risk

Adverse event: Pain, Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 8 affected / 70 at risk

Adverse event: Pain, Muscle (Myalgia)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 6 affected / 70 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 5 affected / 70 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 6 affected / 70 at risk

Adverse event: Blood creatinine increased
Serious: no
Organ System: Investigations
Frequency: 7 affected / 70 at risk