TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT00709111

Adverse event: Bradycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 34 at risk

Adverse event: Upper gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 34 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 34 at risk

Adverse event: Interstitial lung disease
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 34 at risk

Adverse event: Abdominal distension
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 34 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 34 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 34 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 4 affected / 34 at risk

Adverse event: Pneumonia bacterial
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 34 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 34 at risk

Adverse event: Alanine aminotransferase increased
Serious: no
Organ System: Investigations
Frequency: 2 affected / 34 at risk

Adverse event: Aspartate aminotransferase increased
Serious: no
Organ System: Investigations
Frequency: 2 affected / 34 at risk

Adverse event: Blood albumin abnormal
Serious: no
Organ System: Investigations
Frequency: 2 affected / 34 at risk

Adverse event: Blood bilirubin increased
Serious: no
Organ System: Investigations
Frequency: 5 affected / 34 at risk

Adverse event: Blood glucose abnormal
Serious: no
Organ System: Investigations
Frequency: 3 affected / 34 at risk

Adverse event: Blood glucose increased
Serious: no
Organ System: Investigations
Frequency: 4 affected / 34 at risk

Adverse event: Blood sodium decreased
Serious: no
Organ System: Investigations
Frequency: 3 affected / 34 at risk

Adverse event: Neutrophil count decreased
Serious: no
Organ System: Investigations
Frequency: 3 affected / 34 at risk

Adverse event: Platelet count decreased
Serious: no
Organ System: Investigations
Frequency: 3 affected / 34 at risk

Adverse event: Pain in extremity
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 34 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 34 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 5 affected / 34 at risk

Adverse event: Respiratory tract congestion
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 34 at risk

Adverse event: Sinus congestion
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 34 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 34 at risk
Study: NCT00709202

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Notes: Vomited after session which included drinking vanilla milkshake. No sequelae.
Frequency: 1 affected / 19 at risk

Adverse event: Conjunctivitis
Serious: no
Organ System: Eye disorders
Notes: Conjunctivitis (Pink Eye) developed in week 2 of study. Successfully treated with Ciprofloxacin
Frequency: 1 affected / 19 at risk

Adverse event: Chest pain
Serious: no
Organ System: Cardiac disorders
Notes: Chest pain and shortness of breath. Medical examination and labs for pulmonary embolism and cardiac enzymes levels were normal..
Frequency: 1 affected / 20 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Exfoliated skin rash over sun exposed neck area.
Frequency: 1 affected / 20 at risk

Adverse event: Chest pain
Serious: no
Organ System: Psychiatric disorders
Notes: Patient was psychiatrically evaluated for what mother described as difficult behavior after sexual assault.
Frequency: 1 affected / 20 at risk

Adverse event: Increase in level of psychiatric symptoms
Serious: no
Organ System: Psychiatric disorders
Notes: Patient had increase in level of hallucinations, unusual thought content, and suspicious on Brief Psychiatric Rating Scale.
Frequency: 1 affected / 20 at risk
Study: NCT00709228

Adverse event: Pericarditis
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 482 at risk

Adverse event: Vertigo
Serious: yes
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 482 at risk

Adverse event: Hypothyroidism
Serious: yes
Organ System: Endocrine disorders
Frequency: 1 affected / 482 at risk

Adverse event: Pancreatitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 482 at risk

Adverse event: Abscess neck
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 482 at risk

Adverse event: Multiple injuries
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 482 at risk

Adverse event: Acute psychosis
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 482 at risk

Adverse event: Aggression
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 482 at risk

Adverse event: Personality disorder
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 482 at risk

Adverse event: Suicide attempt
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 482 at risk

Adverse event: Thrombosis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 482 at risk
Study: NCT00709319

Adverse event: Retinal detachment
Serious: yes
Organ System: Eye disorders
Frequency: 3 affected / 87 at risk

Adverse event: Endophthalmitis
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 87 at risk

Adverse event: Vitreous haemorrhage
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 87 at risk

Adverse event: Additional vitreomacular interface abnormalities
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 87 at risk

Adverse event: Elevated intraocular pressure requirering treatment
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 87 at risk

Adverse event: Diplopia
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 87 at risk

Adverse event: Lamella hole
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 87 at risk

Adverse event: Choroidal effusion
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 87 at risk
Study: NCT00709735

Adverse event: Relapse of substance abuse
Serious: yes
Organ System: Psychiatric disorders
Notes: One participant in the RP group was withdrawn from the study following his relapse into opioid abuse following his Day 2 participation. This relapse was attributed to the stress of narrating his traumatic event.
Frequency: 1 affected / 12 at risk
Study: NCT00709852

Adverse event: Metastases to central nervous system
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 399 at risk

Adverse event: Hydrocephalus
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 399 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 399 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 11 affected / 399 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 399 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 4 affected / 399 at risk

Adverse event: Blood glucose increased
Serious: no
Organ System: Investigations
Frequency: 4 affected / 399 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 7 affected / 399 at risk

Adverse event: Dysgeusia
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 399 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 13 affected / 399 at risk

Adverse event: Ecchymosis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 399 at risk

Adverse event: General physical health deterioration
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 393 at risk

Adverse event: Somnolence
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 393 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 393 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 17 affected / 393 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 393 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 1 affected / 393 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 393 at risk

Adverse event: Dysgeusia
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 393 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 10 affected / 393 at risk

Adverse event: Ecchymosis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 5 affected / 393 at risk
Study: NCT00709891

Adverse event: Urogenital haemorrhage
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 47208 at risk
Study: NCT00709956

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 31 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 31 at risk

Adverse event: Dysphonia
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 31 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Flushing
Serious: no
Organ System: Vascular disorders
Frequency: 4 affected / 31 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 31 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Pain in extremity
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 31 at risk

Adverse event: Throat irritation
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 5 affected / 31 at risk

Adverse event: Pulmonary arterial hypertension
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 33 at risk

Adverse event: Right ventricular failure
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 33 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 33 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 33 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 33 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 33 at risk

Adverse event: Flushing
Serious: no
Organ System: Vascular disorders
Frequency: 5 affected / 33 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 33 at risk

Adverse event: Muscle tightness
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 33 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 33 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 33 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 2 affected / 33 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 33 at risk

Adverse event: Rhinorrhoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 33 at risk

Adverse event: Throat irritation
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 33 at risk
Study: NCT00710034

Adverse event: Death
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Subject was diagnosed with leiomyosarcoma at week 6 in the study.
Frequency: 1 affected / 195 at risk

Adverse event: Hospitalisation
Serious: yes
Organ System: Psychiatric disorders
Notes: Hospitalization due to suicidal ideation.
Frequency: 1 affected / 196 at risk
Study: NCT00710385

Adverse event: Urticaria
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 17 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 17 at risk

Adverse event: Dizziness
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 17 at risk

Adverse event: Chest discomfort
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 17 at risk

Adverse event: Mild Opioid Withdrawal
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 3 affected / 17 at risk
Study: NCT00710593

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 9 affected / 69 at risk

Adverse event: Local reactions
Serious: no
Organ System: General disorders
Notes: Local reactions include pain and induration.
Frequency: 19 affected / 69 at risk

Adverse event: Systemic Reactions
Serious: no
Organ System: General disorders
Notes: Systemic reactions include: headache, fatigue, malaise, anorexia, arthralgia/myalgia and weakness.
Frequency: 15 affected / 69 at risk

Adverse event: Other Reactions
Serious: no
Organ System: General disorders
Frequency: 5 affected / 69 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 3 affected / 30 at risk

Adverse event: Local reactions
Serious: no
Organ System: General disorders
Notes: Local reactions include pain and induration.
Frequency: 7 affected / 30 at risk

Adverse event: Systemic Reactions
Serious: no
Organ System: General disorders
Notes: Systemic reactions include: headache, fatigue, malaise, anorexia, arthralgia/myalgia and weakness.
Frequency: 9 affected / 30 at risk

Adverse event: Other Reactions
Serious: no
Organ System: General disorders
Frequency: 8 affected / 30 at risk
Study: NCT00710606

Adverse event: fractured pelvis
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 20 at risk

Adverse event: Venous thrombosis
Serious: yes
Organ System: Vascular disorders
Notes: deep vein thrombosis of lower extremity during treatment. additional risk fact was long haul air travel
Frequency: 1 affected / 20 at risk
Study: NCT00710814

Adverse event: Itchiness and bruising at injection site
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 9 affected / 27 at risk

Adverse event: Bruising at injection site
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 4 affected / 27 at risk
Study: NCT00710840

Adverse event: Pulmonary embolism
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 22 at risk

Adverse event: Femoral Notching
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 22 at risk

Adverse event: Retained Cement
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 22 at risk

Adverse event: Hematoma\Excessive Bleeding
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 22 at risk

Adverse event: Hypersensitivity to Light Touch
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 22 at risk

Adverse event: Surgical Malalignment
Serious: no
Organ System: Surgical and medical procedures
Notes: Greater than 4 degrees of varus post-op
Frequency: 4 affected / 22 at risk

Adverse event: Femoral Notching
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 22 at risk

Adverse event: Retained Cement
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 22 at risk

Adverse event: Extraskeletal ossification
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 22 at risk

Adverse event: Retained Drill Bit
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 22 at risk

Adverse event: Intra-Operative Fracture
Serious: no
Organ System: Surgical and medical procedures
Notes: Medial Condyle Fracture
Frequency: 1 affected / 22 at risk

Adverse event: Hematoma\Excessive Bleeding
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 6 affected / 22 at risk

Adverse event: Cellulitis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 22 at risk

Adverse event: Poor Bone Quality
Serious: no
Organ System: General disorders
Notes: Prevented full weight bearing after surgery
Frequency: 1 affected / 22 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Notes: Post-op
Frequency: 1 affected / 22 at risk

Adverse event: Transient EKG Abnormality
Serious: no
Organ System: Cardiac disorders
Notes: Post-op
Frequency: 1 affected / 22 at risk

Adverse event: Surgical Malalignment
Serious: no
Organ System: Surgical and medical procedures
Notes: Greater than 4 degrees of varus post-op
Frequency: 4 affected / 22 at risk
Study: NCT00710905

Adverse event: Retinal detachment
Serious: yes
Organ System: Eye disorders
Notes: non-fatal medical event
Frequency: 1 affected / 50 at risk

Adverse event: Posterior capsule opacification
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 50 at risk

Adverse event: Visual impairment
Serious: no
Organ System: Eye disorders
Notes: Visual disturbances including, but not limited to: floaters and flashes, photopsia
Frequency: 2 affected / 50 at risk

Adverse event: Hypersensitivity
Serious: no
Organ System: Eye disorders
Notes: Mild allergic reaction to prednisolone eye drops
Frequency: 1 affected / 50 at risk

Adverse event: Erythema
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 50 at risk
Study: NCT00710944

Adverse event: Acute lymphangitis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 55 at risk

Adverse event: Prostate cancer
Serious: yes
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 55 at risk

Adverse event: Lung neoplasm malignant
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 58 at risk

Adverse event: Gastric cancer
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 58 at risk
Study: NCT00711022

Adverse event: Obstructed small intestine
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 51 at risk

Adverse event: Cerebrovascular accident
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 51 at risk

Adverse event: Cerebral vascular accident
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 51 at risk

Adverse event: Rectal issue
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 51 at risk

Adverse event: Drug related reaction
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 51 at risk
Study: NCT00711100

Adverse event: Dry mouth
Serious: no
Organ System: General disorders
Frequency: 1 affected / 98 at risk

Adverse event: Excessive Salivation
Serious: no
Organ System: General disorders
Frequency: 6 affected / 98 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: General disorders
Frequency: 2 affected / 98 at risk

Adverse event: Dry mouth
Serious: no
Organ System: General disorders
Frequency: 2 affected / 98 at risk

Adverse event: Excessive Salivation
Serious: no
Organ System: General disorders
Frequency: 2 affected / 98 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 98 at risk

Adverse event: Dry mouth
Serious: no
Organ System: General disorders
Frequency: 3 affected / 98 at risk

Adverse event: Excessive Salivation
Serious: no
Organ System: General disorders
Frequency: 1 affected / 98 at risk

Adverse event: Dizziness/Lightheadedness
Serious: no
Organ System: General disorders
Frequency: 3 affected / 98 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: General disorders
Frequency: 2 affected / 98 at risk

Adverse event: Dry mouth
Serious: no
Organ System: General disorders
Frequency: 1 affected / 98 at risk

Adverse event: Excessive Salivation
Serious: no
Organ System: General disorders
Frequency: 2 affected / 98 at risk

Adverse event: Dizziness/Lightheadedness
Serious: no
Organ System: General disorders
Frequency: 1 affected / 98 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 98 at risk

Adverse event: Excessive Salivation
Serious: no
Organ System: General disorders
Frequency: 14 affected / 98 at risk

Adverse event: Dizziness/Lightheadedness
Serious: no
Organ System: General disorders
Frequency: 3 affected / 98 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: General disorders
Frequency: 6 affected / 98 at risk
Study: NCT00711113

Adverse event: Myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 47 at risk

Adverse event: Subdural haematoma
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 47 at risk

Adverse event: Blod clot in lower leg
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 47 at risk