Study: NCT04264819

Adverse event: Angina pectoris
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 295 at risk

Adverse event: Cardiomyopathy
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 295 at risk

Adverse event: Cyclitis - Study eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Eye haematoma - Study eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Eye inflammation - Study eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Iridocyclitis - Study eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Retinal artery occlusion - Study eye
Serious: yes
Organ System: Eye disorders
Frequency: 2 affected / 295 at risk

Adverse event: Retinal occlusive vasculitis - Study eye
Serious: yes
Organ System: Eye disorders
Frequency: 2 affected / 295 at risk

Adverse event: Uveitis - Study eye
Serious: yes
Organ System: Eye disorders
Frequency: 7 affected / 295 at risk

Adverse event: Vitritis - Study eye
Serious: yes
Organ System: Eye disorders
Frequency: 3 affected / 295 at risk

Adverse event: Chest pain
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 295 at risk

Adverse event: Traumatic intracranial haematoma
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 295 at risk

Adverse event: Dehydration
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 295 at risk

Adverse event: Muscle spasms
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Osteoarthritis
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Gastric cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 295 at risk

Adverse event: Glioblastoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 295 at risk

Adverse event: Hepatic cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 295 at risk

Adverse event: Lung adenocarcinoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 295 at risk

Adverse event: Thyroid cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 295 at risk

Adverse event: Cerebrovascular accident
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 295 at risk

Adverse event: Headache
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 295 at risk

Adverse event: Presyncope
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 295 at risk

Adverse event: Subarachnoid haemorrhage
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 295 at risk

Adverse event: Arrhythmia
Serious: no
Organ System: Cardiac disorders
Frequency: 2 affected / 295 at risk

Adverse event: Atrial fibrillation
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 295 at risk

Adverse event: Vertigo
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 295 at risk

Adverse event: Hypothyroidism
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 295 at risk

Adverse event: Age-related macular degeneration - Fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 295 at risk

Adverse event: Anterior chamber cell - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Blepharitis
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Cataract - Both eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 295 at risk

Adverse event: Cataract - Fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 295 at risk

Adverse event: Cataract - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Chalazion
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 295 at risk

Adverse event: Conjunctival haemorrhage - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 295 at risk

Adverse event: Diplopia - Both eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Dry eye - Both eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Dry eye - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Dyschromatopsia - Both eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Eye inflammation - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 295 at risk

Adverse event: Eye irritation - Both eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Eye irritation - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 295 at risk

Adverse event: Eye pain - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 295 at risk

Adverse event: Eye pruritus - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Eyelid irritation
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Glaucoma - Both eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Iridocyclitis - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 295 at risk

Adverse event: Keratitis - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Lacrimation increased - Both eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Macular hole - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Neovascular age-related macular degeneration - Fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 11 affected / 295 at risk

Adverse event: Neovascular age-related macular degeneration - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Ocular hyperaemia - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Ocular hypertension - Both eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Ocular hypertension - Fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Ocular hypertension - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 10 affected / 295 at risk

Adverse event: Ocular vasculitis - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 295 at risk

Adverse event: Posterior capsule opacification - Both eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Posterior capsule opacification - Fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Posterior capsule opacification - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 295 at risk

Adverse event: Retinal degeneration - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Retinal detachment - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Retinal drusen - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Retinal haemorrhage - Fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Retinal haemorrhage - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 295 at risk

Adverse event: Retinal occlusive vasculitis - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Retinal perivascular sheathing - Fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Retinal perivascular sheathing - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Retinal pigment epithelial tear - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 295 at risk

Adverse event: Retinal tear - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 295 at risk

Adverse event: Retinal vasculitis - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 295 at risk

Adverse event: Serous retinal detachment - Fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Swelling of eyelid
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Uveitis - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Vision blurred - Both eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Vision blurred - Fellow eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Vision blurred - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 295 at risk

Adverse event: Visual acuity reduced - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 295 at risk

Adverse event: Visual field defect - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Vitreous detachment - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 9 affected / 295 at risk

Adverse event: Vitreous floaters - Both eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Vitreous floaters - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 12 affected / 295 at risk

Adverse event: Vitreous haemorrhage - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Vitreous opacities - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 295 at risk

Adverse event: Vitritis - Study eye
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 295 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 295 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 295 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 295 at risk

Adverse event: Gastrooesophageal reflux disease
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 295 at risk

Adverse event: Gingival erosion
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 295 at risk

Adverse event: Inguinal hernia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 295 at risk

Adverse event: Irritable bowel syndrome
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 295 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 295 at risk

Adverse event: Anorectal polyp
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 295 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 295 at risk

Adverse event: Allergy to arthropod sting
Serious: no
Organ System: Immune system disorders
Frequency: 1 affected / 295 at risk

Adverse event: Allergy to synthetic fabric
Serious: no
Organ System: Immune system disorders
Frequency: 1 affected / 295 at risk

Adverse event: Drug hypersensitivity
Serious: no
Organ System: Immune system disorders
Frequency: 1 affected / 295 at risk

Adverse event: Seasonal allergy
Serious: no
Organ System: Immune system disorders
Frequency: 1 affected / 295 at risk

Adverse event: COVID-19
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 295 at risk

Adverse event: Bronchitis
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 295 at risk

Adverse event: COVID-19
Serious: no
Organ System: Infections and infestations
Frequency: 7 affected / 295 at risk

Adverse event: Conjunctivitis - Both eye
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 295 at risk

Adverse event: Conjunctivitis - Study eye
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 295 at risk

Adverse event: Cystitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 295 at risk

Adverse event: Dermatophytosis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 295 at risk

Adverse event: Gastroenteritis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 295 at risk

Adverse event: Herpes ophthalmic - Study eye
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 295 at risk

Adverse event: Herpes zoster
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 295 at risk

Adverse event: Influenza
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 295 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 295 at risk

Adverse event: Onychomycosis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 295 at risk

Adverse event: Otitis externa
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 295 at risk

Adverse event: Periodontitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 295 at risk

Adverse event: Sinusitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 295 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 295 at risk

Adverse event: Foreign body in eye - Both eye
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 295 at risk

Adverse event: Procedural pain - Study eye
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 295 at risk

Adverse event: Spinal fracture
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 295 at risk

Adverse event: Thermal burn - Both eye
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 295 at risk

Adverse event: Upper limb fracture
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 295 at risk

Adverse event: Intraocular pressure increased - Both eye
Serious: no
Organ System: Investigations
Frequency: 1 affected / 295 at risk

Adverse event: Intraocular pressure increased - Study eye
Serious: no
Organ System: Investigations
Frequency: 6 affected / 295 at risk

Adverse event: Prostatic specific antigen increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 295 at risk

Adverse event: SARS-CoV-2 test positive
Serious: no
Organ System: Investigations
Frequency: 1 affected / 295 at risk

Adverse event: Diabetes mellitus
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 3 affected / 295 at risk

Adverse event: Hyperuricaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 295 at risk

Adverse event: Hypokalaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 295 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 295 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 4 affected / 295 at risk

Adverse event: Intervertebral disc protrusion
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Limb discomfort
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Myalgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Osteoarthritis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 295 at risk

Adverse event: Osteoporosis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Pain in extremity
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Tendonitis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Uterine leiomyoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 295 at risk

Adverse event: Amnesia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 295 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 295 at risk

Adverse event: Psychomotor skills impaired
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 295 at risk

Adverse event: Sciatica
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 295 at risk

Adverse event: Tremor
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 295 at risk

Adverse event: Hallucination
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 295 at risk

Adverse event: Hydronephrosis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 295 at risk

Adverse event: Nephrolithiasis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 295 at risk

Adverse event: Renal cyst
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 295 at risk

Adverse event: Urinary incontinence
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 295 at risk

Adverse event: Urinary tract polyp
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 295 at risk

Adverse event: Benign prostatic hyperplasia
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 295 at risk

Adverse event: Bronchospasm
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 295 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 295 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Dermatitis allergic
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Eczema
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Erythema
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Psoriasis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Purpura
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 295 at risk

Adverse event: Arterial stenosis
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 295 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 11 affected / 295 at risk

Adverse event: Hypotension
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 295 at risk

Adverse event: White coat hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 295 at risk