Study: NCT00400946

Adverse event: Infection Gr0-2 neut- bladder
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Infection Gr0-2 neut- cervix
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Infection Gr0-2 neut- middle ear
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Infection w/ gr3-4 neut- sinus
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Intra-op injury Pleura
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 231 at risk

Adverse event: Nausea
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 231 at risk

Adverse event: Nonneuropathic lower extr muscle weak
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 231 at risk

Adverse event: Surgical hemorrhage
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 231 at risk

Adverse event: Urinary electrolyte wasting
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 231 at risk

Adverse event: (ARDS)
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 231 at risk

Adverse event: Colitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 231 at risk

Adverse event: Confusional state
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 231 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 231 at risk

Adverse event: Oesophagitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 231 at risk

Adverse event: Fatigue
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 231 at risk

Adverse event: Infection Gr0-2 neut- wound
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 231 at risk

Adverse event: Infection w/ gr3-4 neut- middle ear
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Infection w/ gr3-4 neut- urinary tract
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Oral gums- pain
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 231 at risk

Adverse event: Pain-other
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 231 at risk

Adverse event: Vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 231 at risk

Adverse event: Constipation
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 231 at risk

Adverse event: Depression
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 231 at risk

Adverse event: Diarrhea w/o prior colostomy
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 231 at risk

Adverse event: Neurologic-other
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 231 at risk

Adverse event: Skin-other
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 231 at risk

Adverse event: Decreased appetite
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 231 at risk

Adverse event: Dehydration
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 231 at risk

Adverse event: Hypophosphataemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 231 at risk

Adverse event: Infection Gr0-2 neut- urinary tract
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 231 at risk

Adverse event: Infection w/ gr3-4 neut- upper airway
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 231 at risk

Adverse event: Neuropathy-sensory
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 231 at risk

Adverse event: Extremity-limb- pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 231 at risk

Adverse event: CNS- hemorrhage
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 231 at risk

Adverse event: Encephalopathy
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 231 at risk

Adverse event: Extremity-lower (gait/walking)
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 231 at risk

Adverse event: Neutrophil count
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 231 at risk

Adverse event: Platelets
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 231 at risk

Adverse event: Gamma-glutamyltransferase
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 231 at risk

Adverse event: Hypoglycaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 231 at risk

Adverse event: Muco/stomatitis (symptom) oral cavity
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 231 at risk

Adverse event: Infection Gr0-2 neut- skin
Serious: yes
Organ System: Infections and infestations
Frequency: 3 affected / 231 at risk

Adverse event: Infection-other
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Pneumonitis/pulmonary infiltrates
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 231 at risk

Adverse event: Hypotension
Serious: yes
Organ System: Vascular disorders
Frequency: 2 affected / 231 at risk

Adverse event: Infection Gr0-2 neut- lung
Serious: yes
Organ System: Infections and infestations
Frequency: 5 affected / 231 at risk

Adverse event: Fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 5 affected / 231 at risk

Adverse event: Hyponatraemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 231 at risk

Adverse event: Haemoglobin
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 4 affected / 231 at risk

Adverse event: Infection w/ gr3-4 neut- skin
Serious: yes
Organ System: Infections and infestations
Frequency: 6 affected / 231 at risk

Adverse event: Colitis- infectious (e.g. C.diff)
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Neuropathy-motor
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 231 at risk

Adverse event: Opportunistic infection lymphopenia>=gr1
Serious: yes
Organ System: Infections and infestations
Frequency: 5 affected / 231 at risk

Adverse event: Osteonecrosis (avascular necrosis)
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 6 affected / 231 at risk

Adverse event: Vascular access-Thrombosis/embolism
Serious: yes
Organ System: Vascular disorders
Frequency: 8 affected / 231 at risk

Adverse event: Blood bilirubin
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 231 at risk

Adverse event: Febrile neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 6 affected / 231 at risk

Adverse event: Hypokalaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 8 affected / 231 at risk

Adverse event: Seizure
Serious: yes
Organ System: Nervous system disorders
Frequency: 6 affected / 231 at risk

Adverse event: Hyperglycaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 6 affected / 231 at risk

Adverse event: Pancreatitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 231 at risk

Adverse event: AST- SGOT
Serious: yes
Organ System: Investigations
Frequency: 4 affected / 231 at risk

Adverse event: Hypersensitivity
Serious: yes
Organ System: Immune system disorders
Frequency: 6 affected / 231 at risk

Adverse event: Amylase
Serious: yes
Organ System: Investigations
Frequency: 5 affected / 231 at risk

Adverse event: Hypertension
Serious: yes
Organ System: Vascular disorders
Frequency: 2 affected / 231 at risk

Adverse event: ALT- SGPT
Serious: yes
Organ System: Investigations
Frequency: 9 affected / 231 at risk

Adverse event: Lipase
Serious: yes
Organ System: Investigations
Frequency: 12 affected / 231 at risk

Adverse event: Thrombosis/thrombus/embolism
Serious: yes
Organ System: Vascular disorders
Frequency: 10 affected / 231 at risk

Adverse event: Hypertriglyceridaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 12 affected / 231 at risk

Adverse event: Muco/stomatitis by exam- oral cavity
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 15 affected / 231 at risk

Adverse event: Infection Gr 0-2 neut- blood
Serious: yes
Organ System: Infections and infestations
Frequency: 33 affected / 231 at risk

Adverse event: Infection w/ gr 3-4 neut- blood
Serious: yes
Organ System: Infections and infestations
Frequency: 25 affected / 231 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 231 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 1 affected / 231 at risk

Adverse event: Infection Gr0-2 neut- bladder
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Infection Gr0-2 neut- bronchus
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Infection Gr0-2 neut- lymphatic
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Infection w/ gr3-4 neut- catheter relate
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Infection w/ gr3-4 neut- larynx
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Infection w/ gr3-4 neut- middle ear
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Infection w/ gr3-4 neut- pharynx
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Infection w/ unk ANC catheter related
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Muscle- pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 231 at risk

Adverse event: Musculoskeletal/soft tissue-other
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 231 at risk

Adverse event: Sinus tachycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 231 at risk

Adverse event: Speech impairment
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 231 at risk

Adverse event: Syncope
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 231 at risk

Adverse event: Hypotension
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 231 at risk

Adverse event: Infection Gr0-2 neut- conjunctiva
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Infection Gr0-2 neut- middle ear
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Infection Gr0-2 neut- wound
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Joint- pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 231 at risk

Adverse event: Personality
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 231 at risk

Adverse event: Bone- pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 231 at risk

Adverse event: Infection Gr0-2 neut- nose
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 231 at risk

Adverse event: Infection Gr0-2 neut- skin
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: ALT- SGPT
Serious: no
Organ System: Investigations
Frequency: 1 affected / 231 at risk

Adverse event: Amylase
Serious: no
Organ System: Investigations
Frequency: 1 affected / 231 at risk

Adverse event: CNS- hemorrhage
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 231 at risk

Adverse event: Extremity-limb- pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 231 at risk

Adverse event: Infection-other
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 231 at risk

Adverse event: Neuropathy-sensory
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 231 at risk

Adverse event: Fever w/o neutropenia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 231 at risk

Adverse event: Pain-other
Serious: no
Organ System: General disorders
Frequency: 1 affected / 231 at risk

Adverse event: Skin-other
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 231 at risk

Adverse event: AST- SGOT
Serious: no
Organ System: Investigations
Frequency: 2 affected / 231 at risk

Adverse event: Colitis- infectious (e.g. C.diff)
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 231 at risk

Adverse event: Vascular access-Thrombosis/embolism
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 231 at risk

Adverse event: Febrile neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 231 at risk

Adverse event: Opportunistic infection lymphopenia>=gr1
Serious: no
Organ System: Infections and infestations
Frequency: 5 affected / 231 at risk

Adverse event: Hypertriglyceridaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 3 affected / 231 at risk

Adverse event: Seizure
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 231 at risk

Adverse event: Thrombosis/thrombus/embolism
Serious: no
Organ System: Vascular disorders
Frequency: 9 affected / 231 at risk

Adverse event: Muco/stomatitis by exam- oral cavity
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 231 at risk

Adverse event: Infection Gr 0-2 neut- blood
Serious: no
Organ System: Infections and infestations
Frequency: 12 affected / 231 at risk

Adverse event: Hypersensitivity
Serious: no
Organ System: Immune system disorders
Frequency: 8 affected / 231 at risk

Adverse event: Osteonecrosis (avascular necrosis)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 15 affected / 231 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 8 affected / 231 at risk

Adverse event: Pancreatitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 15 affected / 231 at risk

Adverse event: Fracture
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 37 affected / 231 at risk

Adverse event: Chyle or lymph leakage
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 232 at risk

Adverse event: Enteritis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Haemolysis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 232 at risk

Adverse event: Infection Gr0-2 neut- muscle
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection Gr0-2 neut- soft tissue
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection w/ gr3-4 neut- brain
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection w/ gr3-4 neut- lip/perioral
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection w/ gr3-4 neut- liver
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection w/ gr3-4 neut- paranasal
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection w/ gr3-4 neut- spleen
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Iron overload
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 232 at risk

Adverse event: Kidney- pain
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 232 at risk

Adverse event: Liver dysfunction/failure
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 232 at risk

Adverse event: Necrosis- pancreas
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Osteoporosis
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 232 at risk

Adverse event: Pain
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 232 at risk

Adverse event: Perforation- stomach
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Peripheral ischaemia
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 232 at risk

Adverse event: Skin breakdown/decubitus ulcer
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 232 at risk

Adverse event: Syncope
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 232 at risk

Adverse event: Ulcer- gastric
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Varices (esophageal)- hemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Agitation
Serious: yes
Organ System: Psychiatric disorders
Frequency: 2 affected / 232 at risk

Adverse event: Fatigue
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 232 at risk

Adverse event: Fever w/o neutropenia
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 232 at risk

Adverse event: Hypercholesterolaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 232 at risk

Adverse event: Infection Gr0-2 neut- abdomen
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection Gr0-2 neut- catheter
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection Gr0-2 neut- eye NOS
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection w/ gr3-4 neut- kidney
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Lower GI- hemorrhage NOS
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Oral gums- pain
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Perforation- small bowel NOS
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Pleural effusion (non-malignant)
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Wound - non-infectious
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 232 at risk

Adverse event: Depression
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 232 at risk

Adverse event: Myelitis
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 232 at risk

Adverse event: Neurologic-other
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 232 at risk

Adverse event: Psychotic disorder
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 232 at risk

Adverse event: Pulmonary/Upper Respiratory-other
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Abdomen- pain
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 232 at risk

Adverse event: Hypophosphataemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 232 at risk

Adverse event: Infection w/ gr3-4 neut- upper airway
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection w/ gr3-4 neut- wound
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Metabolic/Laboratory-other
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 232 at risk

Adverse event: Extremity-limb- pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 232 at risk

Adverse event: CNS- hemorrhage
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 232 at risk

Adverse event: Extremity-lower (gait/walking)
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 232 at risk

Adverse event: Neutrophil count
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 232 at risk

Adverse event: Gamma-glutamyltransferase
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 232 at risk

Adverse event: Hypoglycaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 232 at risk

Adverse event: Infection w/ gr3-4 neut- lung
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Muco/stomatitis (symptom) oral cavity
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 232 at risk

Adverse event: Infection Gr0-2 neut- skin
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 232 at risk

Adverse event: Infection-other
Serious: yes
Organ System: Infections and infestations
Frequency: 3 affected / 232 at risk

Adverse event: Pneumonitis/pulmonary infiltrates
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Hypotension
Serious: yes
Organ System: Vascular disorders
Frequency: 3 affected / 232 at risk

Adverse event: Infection Gr0-2 neut- lung
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 232 at risk

Adverse event: Fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 232 at risk

Adverse event: Hyponatraemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 232 at risk

Adverse event: Infection w/ gr3-4 neut- skin
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Colitis- infectious (e.g. C.diff)
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 232 at risk

Adverse event: Neuropathy-motor
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 232 at risk

Adverse event: Opportunistic infection lymphopenia>=gr1
Serious: yes
Organ System: Infections and infestations
Frequency: 6 affected / 232 at risk

Adverse event: Osteonecrosis (avascular necrosis)
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 6 affected / 232 at risk

Adverse event: Vascular access-Thrombosis/embolism
Serious: yes
Organ System: Vascular disorders
Frequency: 2 affected / 232 at risk

Adverse event: Blood bilirubin
Serious: yes
Organ System: Investigations
Frequency: 4 affected / 232 at risk

Adverse event: Colitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 232 at risk

Adverse event: Febrile neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 7 affected / 232 at risk

Adverse event: Hypokalaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 5 affected / 232 at risk

Adverse event: Seizure
Serious: yes
Organ System: Nervous system disorders
Frequency: 6 affected / 232 at risk

Adverse event: Hyperglycaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 232 at risk

Adverse event: Pancreatitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 9 affected / 232 at risk

Adverse event: AST- SGOT
Serious: yes
Organ System: Investigations
Frequency: 8 affected / 232 at risk

Adverse event: Hypersensitivity
Serious: yes
Organ System: Immune system disorders
Frequency: 14 affected / 232 at risk

Adverse event: Amylase
Serious: yes
Organ System: Investigations
Frequency: 6 affected / 232 at risk

Adverse event: Hypertension
Serious: yes
Organ System: Vascular disorders
Frequency: 3 affected / 232 at risk

Adverse event: ALT- SGPT
Serious: yes
Organ System: Investigations
Frequency: 10 affected / 232 at risk

Adverse event: Lipase
Serious: yes
Organ System: Investigations
Frequency: 10 affected / 232 at risk

Adverse event: Thrombosis/thrombus/embolism
Serious: yes
Organ System: Vascular disorders
Frequency: 12 affected / 232 at risk

Adverse event: Hypertriglyceridaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 20 affected / 232 at risk

Adverse event: Muco/stomatitis by exam- oral cavity
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 21 affected / 232 at risk

Adverse event: Infection Gr 0-2 neut- blood
Serious: yes
Organ System: Infections and infestations
Frequency: 30 affected / 232 at risk

Adverse event: Infection w/ gr 3-4 neut- blood
Serious: yes
Organ System: Infections and infestations
Frequency: 29 affected / 232 at risk

Adverse event: Agitation
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 232 at risk

Adverse event: Allergy-other
Serious: no
Organ System: Immune system disorders
Frequency: 1 affected / 232 at risk

Adverse event: Atelectasis
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Dehydration
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 232 at risk

Adverse event: Hypothermia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 232 at risk

Adverse event: Hypoxia
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Infection Gr0-2 neut- kidney
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection Gr0-2 neut- lung
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection w/ gr3-4 neut- bronchus
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection w/ gr3-4 neut- eye NOS
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection w/ gr3-4 neut- wound
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Neurologic-other
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 232 at risk

Adverse event: Pulmonary/Upper Respiratory-other
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Back- pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 232 at risk

Adverse event: Diarrhea w/o prior colostomy
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Hypotension
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 232 at risk

Adverse event: Infection Gr0-2 neut- conjunctiva
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection Gr0-2 neut- middle ear
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection w/ unk ANC urinary tract NOS
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Pneumonitis/pulmonary infiltrates
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 232 at risk

Adverse event: Infection Gr0-2 neut- sinus
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection Gr0-2 neut- skin
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection Gr0-2 neut- urinary tract
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Infection w/ gr 3-4 neut- blood
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Otitis- middle ear (non-infectious)
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 3 affected / 232 at risk

Adverse event: Amylase
Serious: no
Organ System: Investigations
Frequency: 2 affected / 232 at risk

Adverse event: Colitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Extremity-limb- pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 232 at risk

Adverse event: Infection Gr0-2 neut- oral cavity
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 232 at risk

Adverse event: Fever w/o neutropenia
Serious: no
Organ System: General disorders
Frequency: 4 affected / 232 at risk

Adverse event: Muco/stomatitis (symptom) oral cavity
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 232 at risk

Adverse event: Pain-other
Serious: no
Organ System: General disorders
Frequency: 1 affected / 232 at risk

Adverse event: Skin-other
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 232 at risk

Adverse event: Colitis- infectious (e.g. C.diff)
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Vascular access-Thrombosis/embolism
Serious: no
Organ System: Vascular disorders
Frequency: 3 affected / 232 at risk

Adverse event: Febrile neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 232 at risk

Adverse event: Opportunistic infection lymphopenia>=gr1
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 232 at risk

Adverse event: Hypertriglyceridaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 7 affected / 232 at risk

Adverse event: Seizure
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 232 at risk

Adverse event: Thrombosis/thrombus/embolism
Serious: no
Organ System: Vascular disorders
Frequency: 4 affected / 232 at risk

Adverse event: Muco/stomatitis by exam- oral cavity
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 232 at risk

Adverse event: Infection Gr 0-2 neut- blood
Serious: no
Organ System: Infections and infestations
Frequency: 9 affected / 232 at risk

Adverse event: Hypersensitivity
Serious: no
Organ System: Immune system disorders
Frequency: 13 affected / 232 at risk

Adverse event: Osteonecrosis (avascular necrosis)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 15 affected / 232 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 4 affected / 232 at risk

Adverse event: Pancreatitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 17 affected / 232 at risk

Adverse event: Fracture
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 38 affected / 232 at risk

Adverse event: Capillary leak syndrome
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 794 at risk

Adverse event: ADH secretion abnormality (eg SIADH)
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 794 at risk

Adverse event: Blood alkaline phosphatase
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 794 at risk

Adverse event: Anxiety
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 794 at risk

Adverse event: Atrial flutter
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 794 at risk

Adverse event: Back- pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 794 at risk

Adverse event: Bronchopulmonary- hemorrhage
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Cardiac-other
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 794 at risk

Adverse event: Cecum/appendix- hemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Chyle or lymph leakage
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 794 at risk

Adverse event: CNS cerebrovascular ischemia
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 794 at risk

Adverse event: Coagulation-other
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 794 at risk

Adverse event: Cough
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Blood creatinine
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 794 at risk

Adverse event: Death - multiorgan failure
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 794 at risk

Adverse event: Death - sudden death
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 794 at risk

Adverse event: Edema limb
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 794 at risk

Adverse event: Enteritis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Head/headache
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 794 at risk

Adverse event: Hematologic-other
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 794 at risk

Adverse event: Haemolysis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 794 at risk

Adverse event: Hypoalbuminaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- bladder
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- bronchus
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- cervix
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- dental-tooth
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- middle ear
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- muscle
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- soft tissue
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- spleen
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- brain
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- brain + spinal
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- dental-tooth
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- eye NOS
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- lens
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- lip/perioral
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- liver
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- paranasal
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- pleura
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- sinus
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- spinal cord
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- spleen
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- trachea
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- vein
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ unk ANC abdomen NOS
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ unk ANC colon
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ unk ANC lymphatic
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ unk ANC meninges
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ unk ANC skin (cellulitis)
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ unk ANC ungual (nails)
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ unk ANC upper airway NOS
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ unk ANC urinary tract NOS
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: International normalised ratio
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 794 at risk

Adverse event: Insomnia
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 794 at risk

Adverse event: Intra-op injury Other (Specify)
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 794 at risk

Adverse event: Intra-op injury Pleura
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 794 at risk

Adverse event: Iron overload
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 794 at risk

Adverse event: Joint- pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 794 at risk

Adverse event: Kidney- pain
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 794 at risk

Adverse event: Left ventricular dysfunction
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 794 at risk

Adverse event: Liver dysfunction/failure
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 794 at risk

Adverse event: Lung- hemorrhage
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Muscular/skeletal hypoplasia
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 794 at risk

Adverse event: Nausea
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Necrosis- pancreas
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Nonneuropathic lower extr muscle weak
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 794 at risk

Adverse event: Obstruction-ureteral
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 794 at risk

Adverse event: Oral cavity- pain
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Osteoporosis
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 794 at risk

Adverse event: Pain
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 794 at risk

Adverse event: Pelvic- pain
Serious: yes
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 794 at risk

Adverse event: Perforation- appendix
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 794 at risk

Adverse event: Perforation- stomach
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Peripheral ischaemia
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 794 at risk

Adverse event: Personality
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 794 at risk

Adverse event: Pruritus/itching
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 794 at risk

Adverse event: PTT
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 794 at risk

Adverse event: Sinus tachycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 794 at risk

Adverse event: Skin breakdown/decubitus ulcer
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 794 at risk

Adverse event: Soft tissue necrosis- extremity lower
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 794 at risk

Adverse event: Speech impairment
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 794 at risk

Adverse event: Surgical hemorrhage
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 794 at risk

Adverse event: Syncope
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 794 at risk

Adverse event: Ulcer- anus
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Ulcer- duodenum
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Ulcer- esophagus
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Ulcer- gastric
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Urinary electrolyte wasting
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 794 at risk

Adverse event: Varices (esophageal)- hemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Ventricular tachycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 794 at risk

Adverse event: (ARDS)
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 794 at risk

Adverse event: Agitation
Serious: yes
Organ System: Psychiatric disorders
Frequency: 2 affected / 794 at risk

Adverse event: Bone- pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 794 at risk

Adverse event: Colitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 794 at risk

Adverse event: Confusional state
Serious: yes
Organ System: Psychiatric disorders
Frequency: 2 affected / 794 at risk

Adverse event: Duodenum- hemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 794 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 794 at risk

Adverse event: Oesophagitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 794 at risk

Adverse event: Fatigue
Serious: yes
Organ System: General disorders
Frequency: 2 affected / 794 at risk

Adverse event: Fever w/o neutropenia
Serious: yes
Organ System: General disorders
Frequency: 2 affected / 794 at risk

Adverse event: Hypercholesterolaemia
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 794 at risk

Adverse event: Hyperkalaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 794 at risk

Adverse event: Hyperuricaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- abdomen
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- catheter
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- eye NOS
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- liver
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- peritoneal
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- wound
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- anal/perianal
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- kidney
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- meninges
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- middle ear
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- peritoneal
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- urinary tract
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection w/ unk ANC bladder
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection w/ unk ANC lung
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection w/ unk ANC wound
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Lower GI- hemorrhage NOS
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 794 at risk

Adverse event: Oral gums- pain
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 794 at risk

Adverse event: Pain-other
Serious: yes
Organ System: General disorders
Frequency: 2 affected / 794 at risk

Adverse event: Perforation- small bowel NOS
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 794 at risk

Adverse event: Pleural effusion (non-malignant)
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 794 at risk

Adverse event: Renal failure
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 2 affected / 794 at risk

Adverse event: Vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 794 at risk

Adverse event: Wound - non-infectious
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 794 at risk

Adverse event: Constipation
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 794 at risk

Adverse event: Depression
Serious: yes
Organ System: Psychiatric disorders
Frequency: 3 affected / 794 at risk

Adverse event: Diarrhea w/o prior colostomy
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 794 at risk

Adverse event: Blood fibrinogen
Serious: yes
Organ System: Investigations
Frequency: 3 affected / 794 at risk

Adverse event: Leukocytes
Serious: yes
Organ System: Investigations
Frequency: 3 affected / 794 at risk

Adverse event: Myelitis
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 794 at risk

Adverse event: Neurologic-other
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 794 at risk

Adverse event: Psychotic disorder
Serious: yes
Organ System: Psychiatric disorders
Frequency: 3 affected / 794 at risk

Adverse event: Pulmonary/Upper Respiratory-other
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 794 at risk

Adverse event: Skin-other
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 794 at risk

Adverse event: Upper GI- hemorrhage NOS
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 794 at risk

Adverse event: Abdomen- pain
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 794 at risk

Adverse event: Decreased appetite
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 794 at risk

Adverse event: Dehydration
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 794 at risk

Adverse event: Hypophosphataemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 794 at risk

Adverse event: Ileus
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- urinary tract
Serious: yes
Organ System: Infections and infestations
Frequency: 4 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- catheter relate
Serious: yes
Organ System: Infections and infestations
Frequency: 4 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- upper airway
Serious: yes
Organ System: Infections and infestations
Frequency: 4 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- wound
Serious: yes
Organ System: Infections and infestations
Frequency: 4 affected / 794 at risk

Adverse event: Metabolic/Laboratory-other
Serious: yes
Organ System: Investigations
Frequency: 4 affected / 794 at risk

Adverse event: Neuropathy-sensory
Serious: yes
Organ System: Nervous system disorders
Frequency: 4 affected / 794 at risk

Adverse event: Tumour lysis syndrome
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 794 at risk

Adverse event: Extremity-limb- pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 5 affected / 794 at risk

Adverse event: CNS- hemorrhage
Serious: yes
Organ System: Nervous system disorders
Frequency: 6 affected / 794 at risk

Adverse event: Encephalopathy
Serious: yes
Organ System: Nervous system disorders
Frequency: 6 affected / 794 at risk

Adverse event: Extremity-lower (gait/walking)
Serious: yes
Organ System: General disorders
Frequency: 6 affected / 794 at risk

Adverse event: Hypoxia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 6 affected / 794 at risk

Adverse event: Neutrophil count
Serious: yes
Organ System: Investigations
Frequency: 6 affected / 794 at risk

Adverse event: Platelets
Serious: yes
Organ System: Investigations
Frequency: 6 affected / 794 at risk

Adverse event: Gamma-glutamyltransferase
Serious: yes
Organ System: Investigations
Frequency: 7 affected / 794 at risk

Adverse event: Hypocalcaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 7 affected / 794 at risk

Adverse event: Hypoglycaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 7 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- lung
Serious: yes
Organ System: Infections and infestations
Frequency: 7 affected / 794 at risk

Adverse event: Muco/stomatitis (symptom) oral cavity
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- skin
Serious: yes
Organ System: Infections and infestations
Frequency: 8 affected / 794 at risk

Adverse event: Infection-other
Serious: yes
Organ System: Infections and infestations
Frequency: 9 affected / 794 at risk

Adverse event: Pneumonitis/pulmonary infiltrates
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 9 affected / 794 at risk

Adverse event: Hypotension
Serious: yes
Organ System: Vascular disorders
Frequency: 10 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- lung
Serious: yes
Organ System: Infections and infestations
Frequency: 10 affected / 794 at risk

Adverse event: Fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 11 affected / 794 at risk

Adverse event: Hyponatraemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 11 affected / 794 at risk

Adverse event: Haemoglobin
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 12 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- skin
Serious: yes
Organ System: Infections and infestations
Frequency: 12 affected / 794 at risk

Adverse event: Colitis- infectious (e.g. C.diff)
Serious: yes
Organ System: Infections and infestations
Frequency: 13 affected / 794 at risk

Adverse event: Neuropathy-motor
Serious: yes
Organ System: Nervous system disorders
Frequency: 14 affected / 794 at risk

Adverse event: Opportunistic infection lymphopenia>=gr1
Serious: yes
Organ System: Infections and infestations
Frequency: 15 affected / 794 at risk

Adverse event: Osteonecrosis (avascular necrosis)
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 15 affected / 794 at risk

Adverse event: Vascular access-Thrombosis/embolism
Serious: yes
Organ System: Vascular disorders
Frequency: 15 affected / 794 at risk

Adverse event: Blood bilirubin
Serious: yes
Organ System: Investigations
Frequency: 16 affected / 794 at risk

Adverse event: Colitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 16 affected / 794 at risk

Adverse event: Febrile neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 18 affected / 794 at risk

Adverse event: Hypokalaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 22 affected / 794 at risk

Adverse event: Seizure
Serious: yes
Organ System: Nervous system disorders
Frequency: 22 affected / 794 at risk

Adverse event: Hyperglycaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 25 affected / 794 at risk

Adverse event: Pancreatitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 26 affected / 794 at risk

Adverse event: AST- SGOT
Serious: yes
Organ System: Investigations
Frequency: 28 affected / 794 at risk

Adverse event: Hypersensitivity
Serious: yes
Organ System: Immune system disorders
Frequency: 33 affected / 794 at risk

Adverse event: Amylase
Serious: yes
Organ System: Investigations
Frequency: 37 affected / 794 at risk

Adverse event: Hypertension
Serious: yes
Organ System: Vascular disorders
Frequency: 39 affected / 794 at risk

Adverse event: ALT- SGPT
Serious: yes
Organ System: Investigations
Frequency: 48 affected / 794 at risk

Adverse event: Lipase
Serious: yes
Organ System: Investigations
Frequency: 49 affected / 794 at risk

Adverse event: Thrombosis/thrombus/embolism
Serious: yes
Organ System: Vascular disorders
Frequency: 55 affected / 794 at risk

Adverse event: Hypertriglyceridaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 69 affected / 794 at risk

Adverse event: Muco/stomatitis by exam- oral cavity
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 100 affected / 794 at risk

Adverse event: Infection Gr 0-2 neut- blood
Serious: yes
Organ System: Infections and infestations
Frequency: 103 affected / 794 at risk

Adverse event: Infection w/ gr 3-4 neut- blood
Serious: yes
Organ System: Infections and infestations
Frequency: 234 affected / 794 at risk

Adverse event: Agitation
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 794 at risk

Adverse event: Allergy-other
Serious: no
Organ System: Immune system disorders
Frequency: 1 affected / 794 at risk

Adverse event: Atelectasis
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Chemoradiation dermatitis
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 794 at risk

Adverse event: Chest/thoracic pain NOS
Serious: no
Organ System: General disorders
Frequency: 1 affected / 794 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Blood creatinine
Serious: no
Organ System: Investigations
Frequency: 1 affected / 794 at risk

Adverse event: Dehydration
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 794 at risk

Adverse event: Enteritis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Erythema multiforme
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 794 at risk

Adverse event: Extremity-lower (gait/walking)
Serious: no
Organ System: General disorders
Frequency: 1 affected / 794 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 1 affected / 794 at risk

Adverse event: Haemoglobin
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 794 at risk

Adverse event: Hypoglycaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 794 at risk

Adverse event: Hypothermia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 794 at risk

Adverse event: Hypoxia
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- bladder
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- bronchus
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- external ear
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- eye NOS
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- kidney
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- lung
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- lymphatic
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- meninges
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- bronchus
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- catheter relate
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- eye NOS
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- larynx
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- middle ear
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- peritoneal
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- pharynx
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- urinary tract
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ gr3-4 neut- wound
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ unk ANC catheter related
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ unk ANC skin (cellulitis)
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ unk ANC ungual (nails)
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ unk ANC upper airway NOS
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Infection w/ unk ANC wound
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 794 at risk

Adverse event: Lipase
Serious: no
Organ System: Investigations
Frequency: 1 affected / 794 at risk

Adverse event: Muco/stomatitis (symptom) anus
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Muscle- pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 794 at risk

Adverse event: Musculoskeletal/soft tissue-other
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 794 at risk

Adverse event: Neurologic-other
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 794 at risk

Adverse event: Neutrophil count
Serious: no
Organ System: Investigations
Frequency: 1 affected / 794 at risk

Adverse event: Nonneuropathic lower extr muscle weak
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 794 at risk

Adverse event: Oral cavity- pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Perforation- stomach
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Psychotic disorder
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 794 at risk

Adverse event: Pulmonary/Upper Respiratory-other
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 794 at risk

Adverse event: Sinus tachycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 794 at risk

Adverse event: Speech impairment
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 794 at risk

Adverse event: Syncope
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 794 at risk

Adverse event: Ulcer
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 794 at risk

Adverse event: Weight decreased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 794 at risk

Adverse event: Back- pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 794 at risk

Adverse event: Diarrhea w/o prior colostomy
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 794 at risk

Adverse event: Hyperglycaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 794 at risk

Adverse event: Hypotension
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- conjunctiva
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- middle ear
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- mucosa
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- ungual
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- upper airway
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- wound
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection w/ unk ANC lung
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Infection w/ unk ANC urinary tract NOS
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 794 at risk

Adverse event: Joint- pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 794 at risk

Adverse event: Personality
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 794 at risk

Adverse event: Pneumonitis/pulmonary infiltrates
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 794 at risk

Adverse event: Ulcer- anus
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 794 at risk

Adverse event: Bone- pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- nose
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- sinus
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- skin
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- urinary tract
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 794 at risk

Adverse event: Infection w/ gr 3-4 neut- blood
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 794 at risk

Adverse event: Left ventricular dysfunction
Serious: no
Organ System: Cardiac disorders
Frequency: 3 affected / 794 at risk

Adverse event: Otitis- middle ear (non-infectious)
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 3 affected / 794 at risk

Adverse event: ALT- SGPT
Serious: no
Organ System: Investigations
Frequency: 4 affected / 794 at risk

Adverse event: Amylase
Serious: no
Organ System: Investigations
Frequency: 4 affected / 794 at risk

Adverse event: CNS- hemorrhage
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 794 at risk

Adverse event: Colitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 794 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 794 at risk

Adverse event: Extremity-limb- pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 4 affected / 794 at risk

Adverse event: Infection Gr0-2 neut- oral cavity
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 794 at risk

Adverse event: Infection-other
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 794 at risk

Adverse event: Neuropathy-sensory
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 794 at risk

Adverse event: Colitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 794 at risk

Adverse event: Fever w/o neutropenia
Serious: no
Organ System: General disorders
Frequency: 5 affected / 794 at risk

Adverse event: Muco/stomatitis (symptom) oral cavity
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 794 at risk

Adverse event: Neuropathy-motor
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 794 at risk

Adverse event: Pain-other
Serious: no
Organ System: General disorders
Frequency: 5 affected / 794 at risk

Adverse event: Skin-other
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 5 affected / 794 at risk

Adverse event: AST- SGOT
Serious: no
Organ System: Investigations
Frequency: 6 affected / 794 at risk

Adverse event: Colitis- infectious (e.g. C.diff)
Serious: no
Organ System: Infections and infestations
Frequency: 6 affected / 794 at risk

Adverse event: Vascular access-Thrombosis/embolism
Serious: no
Organ System: Vascular disorders
Frequency: 6 affected / 794 at risk

Adverse event: Febrile neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 7 affected / 794 at risk

Adverse event: Opportunistic infection lymphopenia>=gr1
Serious: no
Organ System: Infections and infestations
Frequency: 10 affected / 794 at risk

Adverse event: Hypertriglyceridaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 14 affected / 794 at risk

Adverse event: Seizure
Serious: no
Organ System: Nervous system disorders
Frequency: 17 affected / 794 at risk

Adverse event: Thrombosis/thrombus/embolism
Serious: no
Organ System: Vascular disorders
Frequency: 22 affected / 794 at risk

Adverse event: Muco/stomatitis by exam- oral cavity
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 31 affected / 794 at risk

Adverse event: Infection Gr 0-2 neut- blood
Serious: no
Organ System: Infections and infestations
Frequency: 32 affected / 794 at risk

Adverse event: Hypersensitivity
Serious: no
Organ System: Immune system disorders
Frequency: 33 affected / 794 at risk

Adverse event: Osteonecrosis (avascular necrosis)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 45 affected / 794 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 58 affected / 794 at risk

Adverse event: Pancreatitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 61 affected / 794 at risk

Adverse event: Fracture
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 118 affected / 794 at risk