TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT01463007

Adverse event: Infection
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: Blood creatinine
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: Hypokalaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: Blood bicarbonate
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: Aspartate aminotransferase
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: Alkaline Phosphatase value
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: Hyperbilirubineamia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: Hypoalbuminaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: Leukocytes
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: Haemoglobin
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: Neutrophil count
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: International normalised ratio
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: PTT
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: Blood fibrinogen
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: Discomfort
Serious: no
Organ System: Investigations
Frequency: 35 affected / 41 at risk

Adverse event: acute skin rxn
Serious: no
Organ System: Investigations
Frequency: 32 affected / 41 at risk

Adverse event: skin induration/fibrosis
Serious: no
Organ System: Investigations
Frequency: 11 affected / 41 at risk

Adverse event: hyperpigmentation
Serious: no
Organ System: Investigations
Frequency: 22 affected / 41 at risk

Adverse event: Fatigue
Serious: no
Organ System: Investigations
Frequency: 18 affected / 41 at risk

Adverse event: breast volume
Serious: no
Organ System: Investigations
Frequency: 11 affected / 41 at risk

Adverse event: Seroma
Serious: no
Organ System: Investigations
Frequency: 2 affected / 41 at risk

Adverse event: Fat necrosis
Serious: no
Organ System: Investigations
Frequency: 2 affected / 41 at risk

Adverse event: Fibrosis Cosmesis
Serious: no
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: Talangiectasis
Serious: no
Organ System: Investigations
Frequency: 8 affected / 41 at risk

Adverse event: Breast pain
Serious: no
Organ System: Investigations
Frequency: 7 affected / 41 at risk

Adverse event: Nausea
Serious: no
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Investigations
Frequency: 1 affected / 41 at risk

Adverse event: Erythema
Serious: no
Organ System: Investigations
Frequency: 1 affected / 41 at risk
Study: NCT01463033

Adverse event: Depression
Serious: yes
Organ System: Psychiatric disorders
Frequency: 7 affected / 66 at risk

Adverse event: Halluscinations
Serious: yes
Organ System: Psychiatric disorders
Frequency: 5 affected / 66 at risk

Adverse event: Suicidality
Serious: yes
Organ System: Psychiatric disorders
Frequency: 3 affected / 66 at risk

Adverse event: Psychotic disorder
Serious: yes
Organ System: Psychiatric disorders
Frequency: 3 affected / 66 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 28 affected / 66 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 28 affected / 66 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 20 affected / 66 at risk

Adverse event: Memory impairment
Serious: no
Organ System: Nervous system disorders
Frequency: 9 affected / 66 at risk

Adverse event: Amnesia
Serious: no
Organ System: Nervous system disorders
Frequency: 8 affected / 66 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Frequency: 15 affected / 66 at risk

Adverse event: Irritability
Serious: no
Organ System: General disorders
Frequency: 10 affected / 66 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 10 affected / 66 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 6 affected / 66 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 5 affected / 66 at risk

Adverse event: Cognitive disorder
Serious: no
Organ System: Nervous system disorders
Frequency: 7 affected / 66 at risk

Adverse event: Ataxia
Serious: no
Organ System: Nervous system disorders
Frequency: 6 affected / 66 at risk

Adverse event: Vertigo
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 66 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 66 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 66 at risk

Adverse event: Weight increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 66 at risk
Study: NCT01463293

Adverse event: Abdominal discomfort
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 74 at risk

Adverse event: Respriatory symptoms
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Upper respiratory tract infection, common cold, bronchitis
Frequency: 5 affected / 74 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 1 affected / 74 at risk

Adverse event: Injury
Serious: no
Organ System: General disorders
Frequency: 1 affected / 74 at risk

Adverse event: Other
Serious: no
Organ System: General disorders
Frequency: 7 affected / 74 at risk

Adverse event: Abdominal discomfort
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 79 at risk

Adverse event: Respriatory symptoms
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Upper respiratory tract infection, common cold, bronchitis
Frequency: 2 affected / 79 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 4 affected / 79 at risk

Adverse event: Other
Serious: no
Organ System: General disorders
Frequency: 6 affected / 79 at risk

Adverse event: Abdominal discomfort
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 71 at risk

Adverse event: Respriatory symptoms
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Upper respiratory tract infection, common cold, bronchitis
Frequency: 1 affected / 71 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 3 affected / 71 at risk

Adverse event: Injury
Serious: no
Organ System: General disorders
Frequency: 3 affected / 71 at risk

Adverse event: Other
Serious: no
Organ System: General disorders
Frequency: 8 affected / 71 at risk
Study: NCT01463670

Adverse event: Atelectasis
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 11 at risk

Adverse event: Atrial fibrillation
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 11 at risk

Adverse event: Vision blurred
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 11 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 11 at risk

Adverse event: Pyrexia
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 11 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 11 at risk

Adverse event: Sepsis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 11 at risk

Adverse event: Skin infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 11 at risk

Adverse event: Embolism
Serious: yes
Organ System: Vascular disorders
Frequency: 2 affected / 11 at risk
Study: NCT01463683

Adverse event: Abortion spontaneous
Serious: yes
Organ System: Pregnancy, puerperium and perinatal conditions
Frequency: 1 affected / 309 at risk

Adverse event: Injection-site erythema
Serious: no
Organ System: General disorders
Frequency: 172 affected / 309 at risk

Adverse event: Injection-site pain
Serious: no
Organ System: General disorders
Frequency: 216 affected / 309 at risk

Adverse event: Injection-site pruritus
Serious: no
Organ System: General disorders
Frequency: 50 affected / 309 at risk

Adverse event: Injection-site swelling
Serious: no
Organ System: General disorders
Frequency: 165 affected / 309 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 12 affected / 309 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 21 affected / 309 at risk

Adverse event: Ectopic pregnancy
Serious: yes
Organ System: Pregnancy, puerperium and perinatal conditions
Frequency: 1 affected / 308 at risk

Adverse event: Abortion induced
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 1 affected / 308 at risk

Adverse event: Injection-site erythema
Serious: no
Organ System: General disorders
Frequency: 152 affected / 308 at risk

Adverse event: Injection-site pain
Serious: no
Organ System: General disorders
Frequency: 194 affected / 308 at risk

Adverse event: Injection-site pruritus
Serious: no
Organ System: General disorders
Frequency: 54 affected / 308 at risk

Adverse event: Injection-site swelling
Serious: no
Organ System: General disorders
Frequency: 149 affected / 308 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 12 affected / 308 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 20 affected / 308 at risk

Adverse event: Injection-site erythema
Serious: no
Organ System: General disorders
Frequency: 26 affected / 104 at risk

Adverse event: Injection-site pain
Serious: no
Organ System: General disorders
Frequency: 62 affected / 104 at risk

Adverse event: Injection-site pruritus
Serious: no
Organ System: General disorders
Frequency: 5 affected / 104 at risk

Adverse event: Injection-site swelling
Serious: no
Organ System: General disorders
Frequency: 26 affected / 104 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 7 affected / 104 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 12 affected / 104 at risk
Study: NCT01464021

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 26 at risk
Study: NCT01464164

Adverse event: Hospitalisation
Serious: yes
Organ System: Infections and infestations
Notes: Cellulitis at injection site of non-study drug with episode of neutropenia.
Frequency: 1 affected / 2 at risk

Adverse event: Hospitalisation
Serious: yes
Organ System: Endocrine disorders
Notes: Shortness of breath and fatigue noted with hypothyroidism
Frequency: 1 affected / 2 at risk

Adverse event: Elevated liver function tests
Serious: yes
Organ System: Infections and infestations
Notes: Subject with elevated LFTs found to have EBV infection .
Frequency: 1 affected / 3 at risk
Study: NCT01464229

Adverse event: Palpitations
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 13 at risk

Adverse event: Increased Irritability
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 13 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 6 affected / 13 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 13 at risk

Adverse event: Headaches
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 13 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 13 at risk

Adverse event: Cramping
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 13 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 13 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 13 at risk

Adverse event: Headaches
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 13 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 13 at risk
Study: NCT01464346

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 90 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 90 at risk

Adverse event: Chest pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 90 at risk

Adverse event: Application site pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 90 at risk

Adverse event: Edema L Hand
Serious: no
Organ System: General disorders
Frequency: 1 affected / 90 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 90 at risk

Adverse event: Influenza
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 90 at risk

Adverse event: Sinusitis
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 90 at risk

Adverse event: Skin infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 90 at risk

Adverse event: Hypoglycaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 90 at risk

Adverse event: Pain in extremity
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 90 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 90 at risk

Adverse event: Limb discomfort
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 90 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 90 at risk

Adverse event: Sinus headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 90 at risk
Study: NCT01464359

Adverse event: Infections and infestations - Other, blood culture w/gram positive cocci and CMV
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 3 at risk

Adverse event: Pyrexia
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 3 at risk

Adverse event: hepatobilliary disorders - Other, veno occlusive disease
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 3 at risk

Adverse event: Febrile neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 3 at risk

Adverse event: Chills
Serious: no
Organ System: General disorders
Frequency: 3 affected / 3 at risk

Adverse event: Injection site reaction
Serious: no
Organ System: General disorders
Frequency: 2 affected / 3 at risk

Adverse event: Cholecystitis
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 3 at risk

Adverse event: Contusion
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 3 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 3 at risk

Adverse event: Hypoxia
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 3 at risk

Adverse event: Pain of skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 3 at risk

Adverse event: other, rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 3 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 3 affected / 3 at risk

Adverse event: Hypotension
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 3 at risk

Adverse event: other, veno occlusive disease
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 3 at risk
Study: NCT01464697

Adverse event: Musculoskeletal, arthritis, connective tissue issues
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 6 affected / 93 at risk

Adverse event: Nausea, GI tract problems
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 8 affected / 93 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 1 affected / 93 at risk

Adverse event: Edema, atrial fibrillation, increased blood pressure, and headache
Serious: no
Organ System: Cardiac disorders
Frequency: 5 affected / 93 at risk

Adverse event: Probable depression
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 93 at risk

Adverse event: Facial acne
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 93 at risk

Adverse event: Musculoskeletal, arthritis, connective tissue issues
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 96 at risk

Adverse event: Nausea, GI tract problems
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 96 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 1 affected / 96 at risk

Adverse event: Edema, atrial fibrillation, increased blood pressure, and headache
Serious: no
Organ System: Cardiac disorders
Frequency: 3 affected / 96 at risk

Adverse event: Worsening VMS
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 96 at risk

Adverse event: Post-traumatic stress
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 96 at risk
Study: NCT01464879

Adverse event: Erythema
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 20 at risk
Study: NCT01465048

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 2 affected / 6 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 6 at risk

Adverse event: Nausea
Serious: no
Organ System: General disorders
Frequency: 1 affected / 6 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 1 affected / 6 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Frequency: 2 affected / 6 at risk

Adverse event: Malasie
Serious: no
Organ System: General disorders
Frequency: 1 affected / 6 at risk

Adverse event: Gingival bleeding
Serious: no
Organ System: General disorders
Frequency: 1 affected / 6 at risk
Study: NCT01465178

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Notes: Two subjects noted experiencing diarrhea over the study course.
Frequency: 2 affected / 31 at risk

Adverse event: Depression
Serious: no
Organ System: Psychiatric disorders
Notes: Two subjects reported a new diagnosis of depression and starting pharmaceutical intervention.
Frequency: 2 affected / 31 at risk
Study: NCT01465230

Adverse event: Deep vein thrombosis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 2 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 2 at risk

Adverse event: Decreased Platlets
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 2 at risk

Adverse event: Sciatica Pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 2 at risk

Adverse event: Bilateral Hand Spasticity
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 2 at risk

Adverse event: Decreased ANC
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 2 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 2 at risk

Adverse event: Decreased Calcium
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 2 at risk

Adverse event: Hypokalaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 2 at risk

Adverse event: Decreased Neutrophil Count
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 2 at risk

Adverse event: Syncope
Serious: no
Organ System: General disorders
Frequency: 1 affected / 2 at risk

Adverse event: Right Groin Pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 2 at risk
Study: NCT01465386

Adverse event: Altered Mental Status
Serious: yes
Organ System: Nervous system disorders
Notes: Serious as required hospitalization, but not related to study drug
Frequency: 1 affected / 6 at risk

Adverse event: Cholechystitis
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Serious as required hospitalization, but not related to study drug
Frequency: 1 affected / 6 at risk

Adverse event: Neuropathy peripheral
Serious: no
Organ System: Nervous system disorders
Notes: Grade 2 peripheral neuropathy, a known adverse effect of study drug
Frequency: 1 affected / 6 at risk
Study: NCT01465412

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 12 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 12 at risk

Adverse event: Dyskinesia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 9 at risk

Adverse event: Toothache
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 9 at risk
Study: NCT01466075

Adverse event: Hypoglycaemia
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 207 at risk
Study: NCT01466127

Adverse event: Bloody Nose
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 16 at risk