Study: NCT00784225

Adverse event: Arrhythmia, NOS
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 3374 at risk

Adverse event: Cardiac ischemia/infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 11 affected / 3374 at risk

Adverse event: Cardiovascular-other
Serious: yes
Organ System: Cardiac disorders
Frequency: 7 affected / 3374 at risk

Adverse event: LVEF decrease/CHF
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 3374 at risk

Adverse event: Ventricular arrhythmia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 3374 at risk

Adverse event: Melena/ GI bleeding
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 3374 at risk

Adverse event: Reportable adverse event, NOS
Serious: yes
Organ System: General disorders
Frequency: 8 affected / 3374 at risk

Adverse event: Respiratory infect w/o neutrop
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 3374 at risk

Adverse event: Second primary
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 3 affected / 3374 at risk

Adverse event: CNS hemorrhage
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 3374 at risk

Adverse event: Cerebrovascular ischemia
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 3374 at risk

Adverse event: Seizure
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 3374 at risk

Adverse event: Emphysema/COPD
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 3374 at risk

Adverse event: Epistaxis
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 3374 at risk

Adverse event: Pulmonary fibrosis
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 3374 at risk

Adverse event: Cardiac ischemia/infarction
Serious: no
Organ System: Cardiac disorders
Frequency: 243 affected / 3374 at risk

Adverse event: Arrhythmia, NOS
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 3356 at risk

Adverse event: Cardiac ischemia/infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 9 affected / 3356 at risk

Adverse event: Cardiovascular-other
Serious: yes
Organ System: Cardiac disorders
Frequency: 9 affected / 3356 at risk

Adverse event: Conduction abnormality/block
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 3356 at risk

Adverse event: Ventricular arrhythmia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 3356 at risk

Adverse event: GI-other
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 3356 at risk

Adverse event: Reportable adverse event, NOS
Serious: yes
Organ System: General disorders
Frequency: 7 affected / 3356 at risk

Adverse event: Second primary
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 4 affected / 3356 at risk

Adverse event: CNS hemorrhage
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 3356 at risk

Adverse event: Cerebrovascular ischemia
Serious: yes
Organ System: Nervous system disorders
Frequency: 4 affected / 3356 at risk

Adverse event: Peripheral sensory neuropathy
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 3356 at risk

Adverse event: Carotid stenosis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 3356 at risk

Adverse event: Peripheral ischaemia
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 3356 at risk

Adverse event: Cardiac ischemia/infarction
Serious: no
Organ System: Cardiac disorders
Frequency: 243 affected / 3356 at risk

Adverse event: Cardiac ischemia/infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 9 affected / 3366 at risk

Adverse event: Cardiovascular-other
Serious: yes
Organ System: Cardiac disorders
Frequency: 15 affected / 3366 at risk

Adverse event: Supraventricular arrhythmia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 3366 at risk

Adverse event: Ventricular arrhythmia
Serious: yes
Organ System: Cardiac disorders
Frequency: 3 affected / 3366 at risk

Adverse event: Vision,NOS
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 3366 at risk

Adverse event: Melena/ GI bleeding
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 3366 at risk

Adverse event: Constitutional symptoms-other
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 3366 at risk

Adverse event: Reportable adverse event, NOS
Serious: yes
Organ System: General disorders
Frequency: 11 affected / 3366 at risk

Adverse event: Respiratory infect w/o neutrop
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 3366 at risk

Adverse event: Surgery-hemorrhage
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 3366 at risk

Adverse event: Weight increased
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 3366 at risk

Adverse event: Second primary
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 3366 at risk

Adverse event: Cerebrovascular ischemia
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 3366 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 3366 at risk

Adverse event: Peripheral ischaemia
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 3366 at risk

Adverse event: Thrombosis/embolism
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 3366 at risk

Adverse event: Cardiac ischemia/infarction
Serious: no
Organ System: Cardiac disorders
Frequency: 261 affected / 3366 at risk

Adverse event: Cardiac ischemia/infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 8 affected / 3374 at risk

Adverse event: Cardiovascular-other
Serious: yes
Organ System: Cardiac disorders
Frequency: 12 affected / 3374 at risk

Adverse event: LVEF decrease/CHF
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 3374 at risk

Adverse event: Ventricular arrhythmia
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 3374 at risk

Adverse event: Eye-other
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 3374 at risk

Adverse event: Hemorrhage w/o 3-4 thrombocyt
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 3374 at risk

Adverse event: Reportable adverse event, NOS
Serious: yes
Organ System: General disorders
Frequency: 8 affected / 3374 at risk

Adverse event: Liver-clinical
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 3374 at risk

Adverse event: Respiratory infect w/o neutrop
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 3374 at risk

Adverse event: Respiratory infection, unk ANC
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 3374 at risk

Adverse event: CNS hemorrhage
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 3374 at risk

Adverse event: Cerebrovascular ischemia
Serious: yes
Organ System: Nervous system disorders
Frequency: 4 affected / 3374 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 3374 at risk

Adverse event: Carotid stenosis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 3374 at risk

Adverse event: Thrombosis/embolism
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 3374 at risk

Adverse event: Cardiac ischemia/infarction
Serious: no
Organ System: Cardiac disorders
Frequency: 267 affected / 3374 at risk