Study: NCT02285920

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 51 at risk

Adverse event: Abdominal pain, diarrhea, GI hemorrhage, nausea, vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 51 at risk

Adverse event: Asthenia, chest pain
Serious: yes
Organ System: General disorders
Frequency: 6 affected / 51 at risk

Adverse event: Hemobilia, hepatic cirrhosis
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 51 at risk

Adverse event: Bacteremia, influenza, osteomyelitis, pneumonia. sepsis, skin graft infection, UTI, viral infection
Serious: yes
Organ System: Infections and infestations
Frequency: 4 affected / 51 at risk

Adverse event: AVfistula site hemorrhage, vascular access complications, fall, laceration, rib fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 6 affected / 51 at risk

Adverse event: Cardiac catheterisation, fistulogram, pleural biopsy
Serious: yes
Organ System: Investigations
Frequency: 4 affected / 51 at risk

Adverse event: Hyperkalemia, hypocalcemia, fluid overload
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 6 affected / 51 at risk

Adverse event: Arthralgia, back pain, neck pain, extremity pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 6 affected / 51 at risk

Adverse event: Balance disorder, dementia, headache, paralysis, syncope
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 51 at risk

Adverse event: Anxiety, depression, mental status changes
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 51 at risk

Adverse event: Bladder mass, hematuria, urinary retention
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 3 affected / 51 at risk

Adverse event: Asthma, COPD, cough , dyspnea, pleural effusion, stridor
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 5 affected / 51 at risk

Adverse event: Blister, erythema, pruritus
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 51 at risk

Adverse event: Angioplasty, catheter placement, toe amputation, renal transplant, thrombectomy, nephrectomy
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 6 affected / 51 at risk

Adverse event: Hypertension, hypotension, thrombosis
Serious: yes
Organ System: Vascular disorders
Frequency: 2 affected / 51 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 51 at risk

Adverse event: Hyperparathyroidism
Serious: no
Organ System: Endocrine disorders
Frequency: 4 affected / 51 at risk

Adverse event: Vision blurred
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 51 at risk

Adverse event: Abdominal pain, nausea, diarrhea, constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 12 affected / 51 at risk

Adverse event: Pain, peripheral edema, malaise
Serious: no
Organ System: General disorders
Frequency: 8 affected / 51 at risk

Adverse event: Bronchitis, diverticulitis, cystitis, cellulitis, naspharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 7 affected / 51 at risk

Adverse event: Fall, rib fracture, vascular graft complication
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 51 at risk

Adverse event: Skin biopsy, liver biopsy, low hemoglobin
Serious: no
Organ System: Investigations
Frequency: 3 affected / 51 at risk

Adverse event: Hyperkalemia, hyperphosphatemia, hypercalcemia, gout
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 22 affected / 51 at risk

Adverse event: Arthralgia, arthritis, osteoarthritis, tendonitis, neck pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 6 affected / 51 at risk

Adverse event: Dizziness, headache, migraine, tremor, syncope
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 51 at risk

Adverse event: Dysuria, hematuria, incontinence
Serious: no
Organ System: Renal and urinary disorders
Frequency: 3 affected / 51 at risk

Adverse event: Breast tenderness, enlargement
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 2 affected / 51 at risk

Adverse event: COPD, pleural effusion, asthma, cough, dyspnea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 51 at risk

Adverse event: Pruritis, rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 4 affected / 51 at risk

Adverse event: AV fistula, thrombectomy, catheter placement, stent placment, amputation, vascular operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 51 at risk

Adverse event: Hypotension
Serious: no
Organ System: Vascular disorders
Frequency: 25 affected / 51 at risk

Adverse event: Acute MI, atrial fibrillation, bradycardia, palpitations
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 27 at risk

Adverse event: Abdominal pain, diarrhea, GI hemorrhage, nausea, vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 27 at risk

Adverse event: Asthenia, chest pain
Serious: yes
Organ System: General disorders
Frequency: 3 affected / 27 at risk

Adverse event: Bacteremia, influenza, osteomyelitis, pneumonia. sepsis, skin graft infection, UTI, viral infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 27 at risk

Adverse event: AVfistula site hemorrhage, vascular access complications, fall, laceration, rib fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 5 affected / 27 at risk

Adverse event: Cardiac catheterisation, fistulogram, pleural biopsy
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 27 at risk

Adverse event: Hyperkalemia, hypocalcemia, fluid overload
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 3 affected / 27 at risk

Adverse event: Balance disorder, dementia, headache, paralysis, syncope
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 27 at risk

Adverse event: Anxiety, depression, mental status changes
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 27 at risk

Adverse event: Asthma, COPD, cough , dyspnea, pleural effusion, stridor
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 27 at risk

Adverse event: Blister, erythema, pruritus
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 27 at risk

Adverse event: Angioplasty, catheter placement, toe amputation, renal transplant, thrombectomy, nephrectomy
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 3 affected / 27 at risk

Adverse event: Hypertension, hypotension, thrombosis
Serious: yes
Organ System: Vascular disorders
Frequency: 5 affected / 27 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 27 at risk

Adverse event: Vertigo
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 27 at risk

Adverse event: Hyperparathyroidism
Serious: no
Organ System: Endocrine disorders
Frequency: 4 affected / 27 at risk

Adverse event: Abdominal pain, nausea, diarrhea, constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 10 affected / 27 at risk

Adverse event: Pain, peripheral edema, malaise
Serious: no
Organ System: General disorders
Frequency: 1 affected / 27 at risk

Adverse event: Bronchitis, diverticulitis, cystitis, cellulitis, naspharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 27 at risk

Adverse event: Fall, rib fracture, vascular graft complication
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 27 at risk

Adverse event: Skin biopsy, liver biopsy, low hemoglobin
Serious: no
Organ System: Investigations
Frequency: 3 affected / 27 at risk

Adverse event: Hyperkalemia, hyperphosphatemia, hypercalcemia, gout
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 10 affected / 27 at risk

Adverse event: Arthralgia, arthritis, osteoarthritis, tendonitis, neck pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 27 at risk

Adverse event: Dizziness, headache, migraine, tremor, syncope
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 27 at risk

Adverse event: Breast tenderness, enlargement
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 27 at risk

Adverse event: COPD, pleural effusion, asthma, cough, dyspnea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 27 at risk

Adverse event: Pruritis, rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 27 at risk

Adverse event: AV fistula, thrombectomy, catheter placement, stent placment, amputation, vascular operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 4 affected / 27 at risk

Adverse event: Hypotension
Serious: no
Organ System: Vascular disorders
Frequency: 14 affected / 27 at risk

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 26 at risk

Adverse event: Acute MI, atrial fibrillation, bradycardia, palpitations
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 26 at risk

Adverse event: Abdominal pain, diarrhea, GI hemorrhage, nausea, vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 26 at risk

Adverse event: Asthenia, chest pain
Serious: yes
Organ System: General disorders
Frequency: 6 affected / 26 at risk

Adverse event: Bacteremia, influenza, osteomyelitis, pneumonia. sepsis, skin graft infection, UTI, viral infection
Serious: yes
Organ System: Infections and infestations
Frequency: 6 affected / 26 at risk

Adverse event: AVfistula site hemorrhage, vascular access complications, fall, laceration, rib fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 5 affected / 26 at risk

Adverse event: Cardiac catheterisation, fistulogram, pleural biopsy
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 26 at risk

Adverse event: Arthralgia, back pain, neck pain, extremity pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 26 at risk

Adverse event: Gastric cancer, renal cell carcinoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 26 at risk

Adverse event: Balance disorder, dementia, headache, paralysis, syncope
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 26 at risk

Adverse event: Asthma, COPD, cough , dyspnea, pleural effusion, stridor
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 5 affected / 26 at risk

Adverse event: Blister, erythema, pruritus
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 26 at risk

Adverse event: Angioplasty, catheter placement, toe amputation, renal transplant, thrombectomy, nephrectomy
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 3 affected / 26 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 26 at risk

Adverse event: Palpitations
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 26 at risk

Adverse event: Hyperparathyroidism
Serious: no
Organ System: Endocrine disorders
Frequency: 6 affected / 26 at risk

Adverse event: Abdominal pain, nausea, diarrhea, constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 26 at risk

Adverse event: Pain, peripheral edema, malaise
Serious: no
Organ System: General disorders
Frequency: 3 affected / 26 at risk

Adverse event: Bronchitis, diverticulitis, cystitis, cellulitis, naspharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 5 affected / 26 at risk

Adverse event: Fall, rib fracture, vascular graft complication
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 26 at risk

Adverse event: Hyperkalemia, hyperphosphatemia, hypercalcemia, gout
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 11 affected / 26 at risk

Adverse event: Arthralgia, arthritis, osteoarthritis, tendonitis, neck pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 4 affected / 26 at risk

Adverse event: Dizziness, headache, migraine, tremor, syncope
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 26 at risk

Adverse event: Breast tenderness, enlargement
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 26 at risk

Adverse event: COPD, pleural effusion, asthma, cough, dyspnea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 26 at risk

Adverse event: Pruritis, rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 26 at risk

Adverse event: Hypotension
Serious: no
Organ System: Vascular disorders
Frequency: 13 affected / 26 at risk

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 25 at risk

Adverse event: Acute MI, atrial fibrillation, bradycardia, palpitations
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 25 at risk

Adverse event: Abdominal pain, diarrhea, GI hemorrhage, nausea, vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 25 at risk

Adverse event: Asthenia, chest pain
Serious: yes
Organ System: General disorders
Frequency: 2 affected / 25 at risk

Adverse event: Hemobilia, hepatic cirrhosis
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 25 at risk

Adverse event: Bacteremia, influenza, osteomyelitis, pneumonia. sepsis, skin graft infection, UTI, viral infection
Serious: yes
Organ System: Infections and infestations
Frequency: 5 affected / 25 at risk

Adverse event: AVfistula site hemorrhage, vascular access complications, fall, laceration, rib fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 3 affected / 25 at risk

Adverse event: Cardiac catheterisation, fistulogram, pleural biopsy
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 25 at risk

Adverse event: Hyperkalemia, hypocalcemia, fluid overload
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 6 affected / 25 at risk

Adverse event: Arthralgia, back pain, neck pain, extremity pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 25 at risk

Adverse event: Gastric cancer, renal cell carcinoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 25 at risk

Adverse event: Anxiety, depression, mental status changes
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 25 at risk

Adverse event: Asthma, COPD, cough , dyspnea, pleural effusion, stridor
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 25 at risk

Adverse event: Blister, erythema, pruritus
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 25 at risk

Adverse event: Angioplasty, catheter placement, toe amputation, renal transplant, thrombectomy, nephrectomy
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 5 affected / 25 at risk

Adverse event: Hypertension, hypotension, thrombosis
Serious: yes
Organ System: Vascular disorders
Frequency: 4 affected / 25 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 25 at risk

Adverse event: Hyperparathyroidism
Serious: no
Organ System: Endocrine disorders
Frequency: 6 affected / 25 at risk

Adverse event: Abdominal pain, nausea, diarrhea, constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 6 affected / 25 at risk

Adverse event: Bronchitis, diverticulitis, cystitis, cellulitis, naspharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 25 at risk

Adverse event: Fall, rib fracture, vascular graft complication
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 3 affected / 25 at risk

Adverse event: Skin biopsy, liver biopsy, low hemoglobin
Serious: no
Organ System: Investigations
Frequency: 2 affected / 25 at risk

Adverse event: Hyperkalemia, hyperphosphatemia, hypercalcemia, gout
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 10 affected / 25 at risk

Adverse event: Arthralgia, arthritis, osteoarthritis, tendonitis, neck pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 4 affected / 25 at risk

Adverse event: Dizziness, headache, migraine, tremor, syncope
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 25 at risk

Adverse event: Breast tenderness, enlargement
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 2 affected / 25 at risk

Adverse event: COPD, pleural effusion, asthma, cough, dyspnea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 25 at risk

Adverse event: Pruritis, rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 25 at risk

Adverse event: AV fistula, thrombectomy, catheter placement, stent placment, amputation, vascular operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 25 at risk

Adverse event: Hypotension
Serious: no
Organ System: Vascular disorders
Frequency: 17 affected / 25 at risk