TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT03110458

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 36 at risk

Adverse event: Folate deficiency
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 36 at risk

Adverse event: Diverticular perforation
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 36 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 36 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 36 at risk

Adverse event: Extra dose administered
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 32 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 7 affected / 32 at risk
Study: NCT03110575

Adverse event: Hypoaesthesia oral
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 29 affected / 97 at risk

Adverse event: Glossodynia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 9 affected / 97 at risk

Adverse event: Paraesthesia oral
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 97 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 9 affected / 97 at risk

Adverse event: Product taste abnormal
Serious: no
Organ System: Product Issues
Frequency: 6 affected / 97 at risk

Adverse event: Hypoaesthesia oral
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 12 affected / 93 at risk

Adverse event: Glossodynia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 93 at risk

Adverse event: Paraesthesia oral
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 93 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 8 affected / 93 at risk

Adverse event: Product taste abnormal
Serious: no
Organ System: Product Issues
Frequency: 4 affected / 93 at risk
Study: NCT03110601

Adverse event: Extradural abscess
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 25 at risk

Adverse event: Lead movement
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 25 at risk
Study: NCT03111316

Adverse event: Neonatal ICU admission
Serious: no
Organ System: Social circumstances
Frequency: 3 affected / 26 at risk

Adverse event: Superimposed preeclampsia
Serious: yes
Organ System: Pregnancy, puerperium and perinatal conditions
Frequency: 1 affected / 24 at risk

Adverse event: Endometritis
Serious: yes
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 24 at risk

Adverse event: Anaemia
Serious: yes
Organ System: Pregnancy, puerperium and perinatal conditions
Frequency: 1 affected / 24 at risk

Adverse event: Pyelonephritis
Serious: yes
Organ System: Pregnancy, puerperium and perinatal conditions
Frequency: 1 affected / 24 at risk

Adverse event: Neonatal ICU admission
Serious: no
Organ System: Social circumstances
Frequency: 3 affected / 25 at risk

Adverse event: Superimposed preeclampsia
Serious: yes
Organ System: Pregnancy, puerperium and perinatal conditions
Frequency: 1 affected / 25 at risk

Adverse event: Neonatal ICU admission
Serious: no
Organ System: Social circumstances
Frequency: 4 affected / 25 at risk
Study: NCT03111407

Adverse event: Poor alignment in tibia component
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 1 affected / 45 at risk

Adverse event: Sepsis in bronchial asthma, infection exacerbation
Serious: yes
Organ System: Infections and infestations
Notes: treated with antibiotics and cortisone
Frequency: 1 affected / 45 at risk

Adverse event: Allergic reaction after eating nuts
Serious: no
Organ System: General disorders
Frequency: 1 affected / 45 at risk

Adverse event: Allergic reaction unclear cause (itching, dyspnea, rash)
Serious: no
Organ System: General disorders
Frequency: 1 affected / 45 at risk

Adverse event: Radius fracture
Serious: no
Organ System: Surgical and medical procedures
Notes: treated by surgery
Frequency: 1 affected / 45 at risk

Adverse event: Flexion Contracture
Serious: no
Organ System: General disorders
Frequency: 1 affected / 45 at risk

Adverse event: Allergic reaction (Dafalgan)
Serious: no
Organ System: General disorders
Notes: treated by stopping the drugs and giving zavegyl/zantic
Frequency: 1 affected / 45 at risk

Adverse event: Foot fracture
Serious: no
Organ System: Surgical and medical procedures
Notes: treated by surgery 1 year later
Frequency: 1 affected / 45 at risk

Adverse event: Delayed Wound Healing
Serious: no
Organ System: Surgical and medical procedures
Notes: treated by wound revision and surgery
Frequency: 1 affected / 45 at risk

Adverse event: Fall from the bed
Serious: no
Organ System: Social circumstances
Notes: Patient and the knee were ok.
Frequency: 1 affected / 45 at risk

Adverse event: Device failure
Serious: yes
Organ System: Surgical and medical procedures
Notes: treated by total knee revision.
Frequency: 1 affected / 27 at risk

Adverse event: Pulmonary embolism
Serious: yes
Organ System: Vascular disorders
Notes: treated with Anticoagulation
Frequency: 1 affected / 27 at risk

Adverse event: Lump in the neck: metastasis,as well as in the lungs
Serious: yes
Organ System: General disorders
Notes: treated by removal and irradiation.
Frequency: 1 affected / 27 at risk

Adverse event: Patella transverse fracture+dislocation of the prosthesis+tibia shaft fracture+infe
Serious: yes
Organ System: Surgical and medical procedures
Notes: adverse events occured in the opposite side (left side).
Frequency: 1 affected / 27 at risk

Adverse event: Flexion Contracture
Serious: no
Organ System: General disorders
Frequency: 1 affected / 27 at risk

Adverse event: Pain in the calf (deep vein thrombosis)
Serious: no
Organ System: Vascular disorders
Notes: treated with xarelto 10mg/day for 3 month
Frequency: 1 affected / 27 at risk

Adverse event: patient felt on the floor, he wanted to stand up alone
Serious: no
Organ System: Social circumstances
Frequency: 1 affected / 27 at risk

Adverse event: Patient still had a joint effusion 6 months after surgery
Serious: no
Organ System: Surgical and medical procedures
Notes: treated by joint puncture
Frequency: 1 affected / 27 at risk
Study: NCT03112993

Adverse event: Transfusion
Serious: yes
Organ System: Surgical and medical procedures
Notes: Perioperative blood transfusion
Frequency: 1 affected / 19 at risk

Adverse event: Hospitalisation
Serious: yes
Organ System: Surgical and medical procedures
Notes: Longer hospital stay than anticipated
Frequency: 2 affected / 19 at risk

Adverse event: ICU admission
Serious: yes
Organ System: Surgical and medical procedures
Notes: Unanticipated ICU admission due to surgical bleeding
Frequency: 1 affected / 21 at risk

Adverse event: Transfusion
Serious: yes
Organ System: Surgical and medical procedures
Notes: Perioperative blood transfusion
Frequency: 2 affected / 21 at risk

Adverse event: Hospitalisation
Serious: yes
Organ System: Surgical and medical procedures
Notes: Longer hospital stay than anticipated
Frequency: 2 affected / 21 at risk
Study: NCT03113383

Adverse event: Multi-organ failure -
Serious: yes
Organ System: General disorders
Frequency: 2 affected / 4 at risk

Adverse event: Cerebrovascular accident
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 4 at risk

Adverse event: Cardiac arrest
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 4 at risk
Study: NCT03113422

Adverse event: Tumour lysis syndrome
Serious: yes
Organ System: Investigations
Frequency: 8 affected / 56 at risk

Adverse event: Back pain
Serious: yes
Organ System: General disorders
Frequency: 2 affected / 56 at risk

Adverse event: Neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 56 at risk

Adverse event: Nausea
Serious: yes
Organ System: General disorders
Frequency: 4 affected / 56 at risk

Adverse event: Pyrexia
Serious: yes
Organ System: General disorders
Frequency: 4 affected / 56 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 56 at risk

Adverse event: Vomitting
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 56 at risk

Adverse event: Cellulitis
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 56 at risk

Adverse event: Infusion related reaction
Serious: yes
Organ System: General disorders
Frequency: 2 affected / 56 at risk

Adverse event: Pneumonitis
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 56 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 46 affected / 56 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 34 affected / 56 at risk

Adverse event: Vomitting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 26 affected / 56 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 24 affected / 56 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 23 affected / 56 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 21 affected / 56 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 16 affected / 56 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 15 affected / 56 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 12 affected / 56 at risk

Adverse event: Infusion related reaction
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 11 affected / 56 at risk

Adverse event: Hyperuricaemia
Serious: no
Organ System: Renal and urinary disorders
Frequency: 10 affected / 56 at risk

Adverse event: AST/ALT increase
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 10 affected / 56 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 10 affected / 56 at risk
Study: NCT03113916

Adverse event: Cholecystectomy
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 102 at risk

Adverse event: Infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 102 at risk

Adverse event: Neurological
Serious: yes
Organ System: Nervous system disorders
Notes: Neurological
Frequency: 1 affected / 102 at risk

Adverse event: Gynecological
Serious: yes
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 102 at risk

Adverse event: Gastrointestinal
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 102 at risk

Adverse event: Hypoglycemia (Expected)
Serious: no
Organ System: Endocrine disorders
Frequency: 12 affected / 102 at risk

Adverse event: Infection
Serious: no
Organ System: Infections and infestations
Frequency: 9 affected / 102 at risk

Adverse event: Musculoskeletal
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 24 affected / 102 at risk

Adverse event: Neurological
Serious: no
Organ System: Nervous system disorders
Frequency: 6 affected / 102 at risk

Adverse event: Urological
Serious: no
Organ System: Renal and urinary disorders
Frequency: 6 affected / 102 at risk

Adverse event: Cholecystectomy
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 98 at risk

Adverse event: Infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 98 at risk

Adverse event: Gastrointestinal
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 9 affected / 98 at risk

Adverse event: Hypoglycemia (Expected)
Serious: no
Organ System: Endocrine disorders
Frequency: 11 affected / 98 at risk

Adverse event: Infection
Serious: no
Organ System: Infections and infestations
Frequency: 17 affected / 98 at risk

Adverse event: Musculoskeletal
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 12 affected / 98 at risk

Adverse event: Neurological
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 98 at risk
Study: NCT03113955

Adverse event: Liver abscess
Serious: yes
Organ System: Hepatobiliary disorders
Notes: There was 6 cases of hepatic abscess reported in the per protocol group
Frequency: 5 affected / 108 at risk

Adverse event: Metastatic neoplasm
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 108 at risk

Adverse event: Hepatic cancer recurrent
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 108 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 108 at risk

Adverse event: Ascites
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 108 at risk

Adverse event: Duodenal ulcer haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 108 at risk

Adverse event: Sepsis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 108 at risk

Adverse event: Jaundice hepatocellular
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 108 at risk

Adverse event: Headache
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 108 at risk

Adverse event: Pyrexia
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 108 at risk

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 108 at risk

Adverse event: Post embolisation syndrome
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 108 at risk

Adverse event: Investigations
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 23 affected / 108 at risk

Adverse event: Gastrointestinal disorders
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 27 affected / 108 at risk

Adverse event: Injury, poisoning and procedural complications
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 60 affected / 108 at risk

Adverse event: General disorders and administration site conditions
Serious: no
Organ System: General disorders
Frequency: 14 affected / 108 at risk

Adverse event: Hepatobiliary disorders
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 14 affected / 108 at risk

Adverse event: Blood and lymphatic system disorders
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 6 affected / 108 at risk

Adverse event: Metabolism and nutrition disorders
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 7 affected / 108 at risk
Study: NCT03113968

Adverse event: Infection requiring antibiotics
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 170 at risk

Adverse event: Homicidal ideation
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 170 at risk

Adverse event: Suicidal ideation
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 170 at risk

Adverse event: Cardiac arrest
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 170 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 12 affected / 170 at risk

Adverse event: Hypertension (severe / prolonged)
Serious: no
Organ System: Cardiac disorders
Frequency: 4 affected / 170 at risk

Adverse event: Muscle Pain / Weakness
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 9 affected / 170 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 6 affected / 170 at risk

Adverse event: Non-Cardiac Jaw Pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 4 affected / 170 at risk

Adverse event: Panic
Serious: no
Organ System: Psychiatric disorders
Frequency: 3 affected / 170 at risk

Adverse event: Suicidal ideation
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 170 at risk

Adverse event: Chest pain
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 195 at risk

Adverse event: Aborted suicide attempt (gesture)
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 195 at risk

Adverse event: Suicidal ideation
Serious: yes
Organ System: Psychiatric disorders
Frequency: 3 affected / 195 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 16 affected / 195 at risk

Adverse event: Hypertension (severe / prolonged)
Serious: no
Organ System: Cardiac disorders
Frequency: 6 affected / 195 at risk

Adverse event: Muscle Pain / Weakness
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 195 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 10 affected / 195 at risk

Adverse event: Panic
Serious: no
Organ System: Psychiatric disorders
Frequency: 4 affected / 195 at risk

Adverse event: Suicidal ideation
Serious: no
Organ System: Psychiatric disorders
Frequency: 4 affected / 195 at risk
Study: NCT03114059

Adverse event: Hypersensitivity
Serious: no
Organ System: Eye disorders
Notes: itching, watery secretion, redning of the lids
Frequency: 1 affected / 75 at risk
Study: NCT03114891

Adverse event: Headache
Serious: no
Organ System: General disorders
Notes: TMS-induced headache.
Frequency: 4 affected / 24 at risk

Adverse event: Scalp muscle/Facial muscle pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Muscle tenderness or pain in scalp and/or facial muscles during/after TMS stimulation.
Frequency: 1 affected / 24 at risk

Adverse event: Pain in jaw
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Jaw pain from TMS muscle activation.
Frequency: 1 affected / 24 at risk

Adverse event: Bell's palsy
Serious: no
Organ System: Nervous system disorders
Notes: Participant developed and was diagnosed with Bell's Palsy during first six days of TMS treatment. It was determined this was unrelated to study procedures.
Frequency: 1 affected / 24 at risk

Adverse event: Worsening of symptoms
Serious: no
Organ System: Psychiatric disorders
Notes: Subjects reported increase in anxiety and suicidal symptoms/behaviors during their study participation. PI determined this was unrelated to study procedures.
Frequency: 2 affected / 24 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Notes: TMS-induced headache.
Frequency: 2 affected / 21 at risk

Adverse event: Scalp muscle/Facial muscle pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Muscle tenderness or pain in scalp and/or facial muscles during/after TMS stimulation.
Frequency: 1 affected / 21 at risk

Adverse event: Pain in jaw
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Jaw pain from TMS muscle activation.
Frequency: 1 affected / 21 at risk

Adverse event: Dizziness and disorientation
Serious: no
Organ System: Nervous system disorders
Notes: Dizziness and disorientation after TMS administration.
Frequency: 1 affected / 21 at risk
Study: NCT03114969

Adverse event: Chronic obstructive
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 50 at risk

Adverse event: Chronic obstructive
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 50 at risk

Adverse event: Chronic obstructive
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 50 at risk

Adverse event: Appendicitis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 51 at risk

Adverse event: Chronic obstructive
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 51 at risk

Adverse event: Chest pain
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 49 at risk

Adverse event: Chronic obstructive
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 49 at risk

Adverse event: Chronic obstructive
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 50 at risk

Adverse event: Chronic obstructive pulmonary disease
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 50 at risk

Adverse event: Chronic obstructive
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 50 at risk

Adverse event: Chronic obstructive
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 5 affected / 50 at risk
Study: NCT03114995

Adverse event: Minor bleeding
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Minor bleeding defined by TIMI criteria
Frequency: 4 affected / 30 at risk

Adverse event: Minor bleeding
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Minor bleeding defined by TIMI criteria
Frequency: 1 affected / 30 at risk

Adverse event: Minor bleeding
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Minor bleeding defined by TIMI criteria
Frequency: 8 affected / 78 at risk