Study: NCT01747447

Adverse event: Malignant Cancer
Serious: yes
Organ System: General disorders
Frequency: 22 affected / 388 at risk

Adverse event: Major Cardiovascular Events
Serious: yes
Organ System: Cardiac disorders
Frequency: 7 affected / 388 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 10 affected / 388 at risk

Adverse event: Hypercalcaemia
Serious: yes
Organ System: Endocrine disorders
Frequency: 3 affected / 388 at risk

Adverse event: Nephrolithiasis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 17 affected / 388 at risk

Adverse event: Parathyroid Condition
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 388 at risk

Adverse event: Kidney Failure or Dialysis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 388 at risk

Adverse event: Blood urine present
Serious: no
Organ System: Renal and urinary disorders
Frequency: 18 affected / 388 at risk

Adverse event: Easy Bruising
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 62 affected / 388 at risk

Adverse event: Frequent Nosebleeds
Serious: no
Organ System: General disorders
Frequency: 10 affected / 388 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 145 affected / 388 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 88 affected / 388 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 121 affected / 388 at risk

Adverse event: Malignant Cancer
Serious: yes
Organ System: General disorders
Frequency: 19 affected / 383 at risk

Adverse event: Major Cardiovascular Events
Serious: yes
Organ System: Cardiac disorders
Frequency: 4 affected / 383 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 10 affected / 383 at risk

Adverse event: Hypercalcaemia
Serious: yes
Organ System: Endocrine disorders
Frequency: 5 affected / 383 at risk

Adverse event: Nephrolithiasis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 11 affected / 383 at risk

Adverse event: Parathyroid Condition
Serious: no
Organ System: Endocrine disorders
Frequency: 4 affected / 383 at risk

Adverse event: Blood urine present
Serious: no
Organ System: Renal and urinary disorders
Frequency: 27 affected / 383 at risk

Adverse event: Easy Bruising
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 61 affected / 383 at risk

Adverse event: Frequent Nosebleeds
Serious: no
Organ System: General disorders
Frequency: 20 affected / 383 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 128 affected / 383 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 77 affected / 383 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 133 affected / 383 at risk

Adverse event: Malignant Cancer
Serious: yes
Organ System: General disorders
Frequency: 15 affected / 388 at risk

Adverse event: Major Cardiovascular Events
Serious: yes
Organ System: Cardiac disorders
Frequency: 7 affected / 388 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 9 affected / 388 at risk

Adverse event: Hypercalcaemia
Serious: yes
Organ System: Endocrine disorders
Frequency: 7 affected / 388 at risk

Adverse event: Nephrolithiasis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 16 affected / 388 at risk

Adverse event: Parathyroid Condition
Serious: no
Organ System: Endocrine disorders
Frequency: 3 affected / 388 at risk

Adverse event: Kidney Failure or Dialysis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 388 at risk

Adverse event: Blood urine present
Serious: no
Organ System: Renal and urinary disorders
Frequency: 22 affected / 388 at risk

Adverse event: Easy Bruising
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 59 affected / 388 at risk

Adverse event: Frequent Nosebleeds
Serious: no
Organ System: General disorders
Frequency: 17 affected / 388 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 139 affected / 388 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 80 affected / 388 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 118 affected / 388 at risk

Adverse event: Malignant Cancer
Serious: yes
Organ System: General disorders
Frequency: 26 affected / 383 at risk

Adverse event: Major Cardiovascular Events
Serious: yes
Organ System: Cardiac disorders
Frequency: 4 affected / 383 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 11 affected / 383 at risk

Adverse event: Hypercalcaemia
Serious: yes
Organ System: Endocrine disorders
Frequency: 1 affected / 383 at risk

Adverse event: Nephrolithiasis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 12 affected / 383 at risk

Adverse event: Parathyroid Condition
Serious: no
Organ System: Endocrine disorders
Frequency: 2 affected / 383 at risk

Adverse event: Blood urine present
Serious: no
Organ System: Renal and urinary disorders
Frequency: 23 affected / 383 at risk

Adverse event: Easy Bruising
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 64 affected / 383 at risk

Adverse event: Frequent Nosebleeds
Serious: no
Organ System: General disorders
Frequency: 13 affected / 383 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 134 affected / 383 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 85 affected / 383 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 136 affected / 383 at risk

Adverse event: Malignant Cancer
Serious: yes
Organ System: General disorders
Frequency: 9 affected / 193 at risk

Adverse event: Major Cardiovascular Events
Serious: yes
Organ System: Cardiac disorders
Frequency: 5 affected / 193 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 6 affected / 193 at risk

Adverse event: Hypercalcaemia
Serious: yes
Organ System: Endocrine disorders
Frequency: 3 affected / 193 at risk

Adverse event: Nephrolithiasis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 10 affected / 193 at risk

Adverse event: Kidney Failure or Dialysis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 193 at risk

Adverse event: Blood urine present
Serious: no
Organ System: Renal and urinary disorders
Frequency: 8 affected / 193 at risk

Adverse event: Easy Bruising
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 29 affected / 193 at risk

Adverse event: Frequent Nosebleeds
Serious: no
Organ System: General disorders
Frequency: 7 affected / 193 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 77 affected / 193 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 43 affected / 193 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 53 affected / 193 at risk

Adverse event: Malignant Cancer
Serious: yes
Organ System: General disorders
Frequency: 13 affected / 195 at risk

Adverse event: Major Cardiovascular Events
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 195 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 195 at risk

Adverse event: Nephrolithiasis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 7 affected / 195 at risk

Adverse event: Parathyroid Condition
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 195 at risk

Adverse event: Blood urine present
Serious: no
Organ System: Renal and urinary disorders
Frequency: 10 affected / 195 at risk

Adverse event: Easy Bruising
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 33 affected / 195 at risk

Adverse event: Frequent Nosebleeds
Serious: no
Organ System: General disorders
Frequency: 3 affected / 195 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 68 affected / 195 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 45 affected / 195 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 68 affected / 195 at risk

Adverse event: Malignant Cancer
Serious: yes
Organ System: General disorders
Frequency: 6 affected / 195 at risk

Adverse event: Major Cardiovascular Events
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 195 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 195 at risk

Adverse event: Hypercalcaemia
Serious: yes
Organ System: Endocrine disorders
Frequency: 4 affected / 195 at risk

Adverse event: Nephrolithiasis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 6 affected / 195 at risk

Adverse event: Parathyroid Condition
Serious: no
Organ System: Endocrine disorders
Frequency: 3 affected / 195 at risk

Adverse event: Blood urine present
Serious: no
Organ System: Renal and urinary disorders
Frequency: 14 affected / 195 at risk

Adverse event: Easy Bruising
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 30 affected / 195 at risk

Adverse event: Frequent Nosebleeds
Serious: no
Organ System: General disorders
Frequency: 10 affected / 195 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 62 affected / 195 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 37 affected / 195 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 65 affected / 195 at risk

Adverse event: Malignant Cancer
Serious: yes
Organ System: General disorders
Frequency: 13 affected / 188 at risk

Adverse event: Major Cardiovascular Events
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 188 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 188 at risk

Adverse event: Hypercalcaemia
Serious: yes
Organ System: Endocrine disorders
Frequency: 1 affected / 188 at risk

Adverse event: Nephrolithiasis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 5 affected / 188 at risk

Adverse event: Parathyroid Condition
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 188 at risk

Adverse event: Blood urine present
Serious: no
Organ System: Renal and urinary disorders
Frequency: 13 affected / 188 at risk

Adverse event: Easy Bruising
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 31 affected / 188 at risk

Adverse event: Frequent Nosebleeds
Serious: no
Organ System: General disorders
Frequency: 10 affected / 188 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 66 affected / 188 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 40 affected / 188 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 68 affected / 188 at risk