Study: NCT00320788

Adverse event: Back pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 32 at risk

Adverse event: Non-Hodgkin's lymphoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 32 at risk

Adverse event: Intestinal obstruction
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 32 at risk

Adverse event: Small intestinal obstruction
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 32 at risk

Adverse event: Atrial fibrillation
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 32 at risk

Adverse event: Atrioventricular block complete
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 32 at risk

Adverse event: Cardiac failure congestive
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 32 at risk

Adverse event: Gastroenteritis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 32 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 32 at risk

Adverse event: Fall
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 32 at risk

Adverse event: Synovial rupture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 32 at risk

Adverse event: Stress urinary incontinence
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 32 at risk

Adverse event: Carotid artery occlusion
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 32 at risk

Adverse event: Cerebrovascular accident
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 32 at risk

Adverse event: Spinal cord disorder
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 32 at risk

Adverse event: Chronic obstructive pulmonary disease
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 32 at risk

Adverse event: Uveitis
Serious: yes
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 32 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 32 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 6 affected / 32 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 32 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 32 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 32 at risk

Adverse event: Chest pain
Serious: no
Organ System: General disorders
Frequency: 2 affected / 32 at risk

Adverse event: Angina pectoris
Serious: no
Organ System: Cardiac disorders
Frequency: 2 affected / 32 at risk

Adverse event: Bradycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 32 at risk

Adverse event: Seasonal allergy
Serious: no
Organ System: Immune system disorders
Frequency: 4 affected / 32 at risk

Adverse event: Bronchitis
Serious: no
Organ System: Infections and infestations
Frequency: 5 affected / 32 at risk

Adverse event: Cystitis
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 32 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 32 at risk

Adverse event: Pneumonia
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 32 at risk

Adverse event: Sinusitis
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 32 at risk

Adverse event: Tooth abscess
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 32 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 32 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 32 at risk

Adverse event: Fall
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 32 at risk

Adverse event: Dehydration
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 32 at risk

Adverse event: Gout
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 32 at risk

Adverse event: Hypercholesterolaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 32 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 32 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 32 at risk

Adverse event: Sinus headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 32 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 32 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 32 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 32 at risk

Adverse event: Laryngeal pain
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 32 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 32 at risk

Adverse event: Blepharitis
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 32 at risk

Adverse event: Cataract nuclear
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 3 affected / 32 at risk

Adverse event: Conjunctival haemorrhage
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 32 at risk

Adverse event: Detachment of retinal pigment epithelium
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 32 at risk

Adverse event: Dry eye
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 32 at risk

Adverse event: Refraction disorder
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 32 at risk

Adverse event: Retinal oedema
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 32 at risk

Adverse event: Retinal pigment epitheliopathy
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 32 at risk

Adverse event: Visual acuity reduced
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 32 at risk

Adverse event: Vitreous detachment
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 4 affected / 32 at risk

Adverse event: Vitreous floaters
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 32 at risk

Adverse event: Intraocular pressure increased
Serious: no
Organ System: Investigations
Notes: Fellow Eye
Frequency: 1 affected / 32 at risk

Adverse event: Eye inflammation
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 2 affected / 32 at risk

Adverse event: Eye irritation
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 5 affected / 32 at risk

Adverse event: Eye pain
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 5 affected / 32 at risk

Adverse event: Foreign body sensation in eyes
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 3 affected / 32 at risk

Adverse event: Maculopathy
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 32 at risk

Adverse event: Photopsia
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 32 at risk

Adverse event: Retinal depigmentation
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 2 affected / 32 at risk

Adverse event: Subretinal fibrosis
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 2 affected / 32 at risk

Adverse event: Vision blurred
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 2 affected / 32 at risk

Adverse event: Visual impairment
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 2 affected / 32 at risk

Adverse event: Brain neoplasm malignant
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 32 at risk

Adverse event: Colon cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 32 at risk

Adverse event: Deep vein thrombosis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 32 at risk

Adverse event: Non-cardiac chest pain
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 32 at risk

Adverse event: Hip fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 32 at risk

Adverse event: Urinary retention
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 32 at risk

Adverse event: Pilonidal sinus repair
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 1 affected / 32 at risk

Adverse event: Retinal detachment
Serious: yes
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 32 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 32 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 32 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 32 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 32 at risk

Adverse event: Flatulence
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 32 at risk

Adverse event: Seasonal allergy
Serious: no
Organ System: Immune system disorders
Frequency: 2 affected / 32 at risk

Adverse event: Bronchitis
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 32 at risk

Adverse event: Herpes zoster
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 32 at risk

Adverse event: Influenza
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 32 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 32 at risk

Adverse event: Sinusitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 32 at risk

Adverse event: Tooth abscess
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 32 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 32 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 32 at risk

Adverse event: Vulvovaginal mycotic infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 32 at risk

Adverse event: Fall
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 32 at risk

Adverse event: Blood creatinine increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 32 at risk

Adverse event: Blood glucose increased
Serious: no
Organ System: Investigations
Frequency: 2 affected / 32 at risk

Adverse event: Blood urea increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 32 at risk

Adverse event: Dehydration
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 32 at risk

Adverse event: Gout
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 32 at risk

Adverse event: Dementia Alzheimer's type
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 32 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 32 at risk

Adverse event: Sinus headache
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 32 at risk

Adverse event: Depression
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 32 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 32 at risk

Adverse event: Cataract
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 32 at risk

Adverse event: Cataract subcapsular
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 32 at risk

Adverse event: Choroidal neovascularisation
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 32 at risk

Adverse event: Detachment of retinal pigment epithelium
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 32 at risk

Adverse event: Refraction disorder
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 4 affected / 32 at risk

Adverse event: Retinal haemorrhage
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 32 at risk

Adverse event: Retinal oedema
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 32 at risk

Adverse event: Retinal pigment epitheliopathy
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 3 affected / 32 at risk

Adverse event: Visual acuity reduced
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 32 at risk

Adverse event: Vitreous detachment
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 32 at risk

Adverse event: Intraocular pressure increased
Serious: no
Organ System: Investigations
Notes: Fellow Eye
Frequency: 3 affected / 32 at risk

Adverse event: Eye pain
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 2 affected / 32 at risk

Adverse event: Subretinal fibrosis
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 32 at risk

Adverse event: Visual impairment
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 32 at risk

Adverse event: Osteoarthritis
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 31 at risk

Adverse event: Pancreatic carcinoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 31 at risk

Adverse event: Squamous cell carcinoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 31 at risk

Adverse event: Dyskinesia oesophageal
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Volvulus
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Asthenia
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 31 at risk

Adverse event: Angina pectoris
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 31 at risk

Adverse event: Cardiac failure congestive
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 31 at risk

Adverse event: Coronary artery disease
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 31 at risk

Adverse event: Bronchitis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Cellulitis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 31 at risk

Adverse event: Urinary tract infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Fall
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 31 at risk

Adverse event: Hip fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 31 at risk

Adverse event: Renal failure
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 31 at risk

Adverse event: Coordination abnormal
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 31 at risk

Adverse event: Dysarthria
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 31 at risk

Adverse event: Transient ischaemic attack
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 31 at risk

Adverse event: Pneumonia aspiration
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 31 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 31 at risk

Adverse event: Osteoarthritis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 31 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 31 at risk

Adverse event: Hypotension
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 31 at risk

Adverse event: Angina pectoris
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 31 at risk

Adverse event: Bradycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 2 affected / 31 at risk

Adverse event: Bronchitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Cystitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Gastroenteritis viral
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 31 at risk

Adverse event: Influenza
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 31 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 31 at risk

Adverse event: Pneumonia
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 31 at risk

Adverse event: Rhinovirus infection
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 31 at risk

Adverse event: Sinusitis
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 31 at risk

Adverse event: Tooth abscess
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 31 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 6 affected / 31 at risk

Adverse event: Fall
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 31 at risk

Adverse event: Blood glucose increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 31 at risk

Adverse event: Dehydration
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 31 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 31 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 31 at risk

Adverse event: Sinus headache
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 31 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 31 at risk

Adverse event: Depression
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 31 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 31 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 31 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 31 at risk

Adverse event: Blepharitis
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 31 at risk

Adverse event: Cataract
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Cataract nuclear
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 31 at risk

Adverse event: Choroidal neovascularisation
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 31 at risk

Adverse event: Conjunctival haemorrhage
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 31 at risk

Adverse event: Dry eye
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Refraction disorder
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Retinal haemorrhage
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Retinal oedema
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Visual acuity reduced
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 4 affected / 31 at risk

Adverse event: Vitreous detachment
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 31 at risk

Adverse event: Intraocular pressure increased
Serious: no
Organ System: Investigations
Notes: Fellow Eye
Frequency: 3 affected / 31 at risk

Adverse event: Eye irritation
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 31 at risk

Adverse event: Eye pain
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 4 affected / 31 at risk

Adverse event: Foreign body sensation in eyes
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 31 at risk

Adverse event: Punctate keratitis
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 31 at risk

Adverse event: Subretinal fibrosis
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 31 at risk

Adverse event: Spinal osteoarthritis
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 31 at risk

Adverse event: Metastases to lung
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 31 at risk

Adverse event: Thyroid neoplasm
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 31 at risk

Adverse event: Transitional cell carcinoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 31 at risk

Adverse event: Bronchitis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Urinary tract infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Skin laceration
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 31 at risk

Adverse event: Pulmonary embolism
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Angina pectoris
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 31 at risk

Adverse event: Bronchitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Cellulitis
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 31 at risk

Adverse event: Cystitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Pneumonia
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Sinusitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Tooth abscess
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 31 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 6 affected / 31 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Vulvovaginal mycotic infection
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 31 at risk

Adverse event: Blood creatinine increased
Serious: no
Organ System: Investigations
Frequency: 2 affected / 31 at risk

Adverse event: Blood glucose increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 31 at risk

Adverse event: Blood urea increased
Serious: no
Organ System: Investigations
Frequency: 2 affected / 31 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 31 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 31 at risk

Adverse event: Blepharitis
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 3 affected / 31 at risk

Adverse event: Cataract
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Cataract nuclear
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Cataract subcapsular
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Choroidal neovascularisation
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Conjunctival haemorrhage
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 31 at risk

Adverse event: Dry eye
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 31 at risk

Adverse event: Refraction disorder
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Retinal haemorrhage
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 3 affected / 31 at risk

Adverse event: Retinal pigment epitheliopathy
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Visual acuity reduced
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Vitreous detachment
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 3 affected / 31 at risk

Adverse event: Vitreous floaters
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Intraocular pressure increased
Serious: no
Organ System: Investigations
Notes: Fellow Eye
Frequency: 2 affected / 31 at risk

Adverse event: Eye inflammation
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 31 at risk

Adverse event: Eye pain
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 31 at risk

Adverse event: Maculopathy
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 2 affected / 31 at risk

Adverse event: Photopsia
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 2 affected / 31 at risk

Adverse event: Punctate keratitis
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 2 affected / 31 at risk

Adverse event: Subretinal fibrosis
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 2 affected / 31 at risk

Adverse event: Visual impairment
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 2 affected / 31 at risk

Adverse event: Atrioventricular block complete
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 31 at risk

Adverse event: Bradycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 31 at risk

Adverse event: Pulmonary hypertension
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Intraocular pressure increased
Serious: yes
Organ System: Investigations
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Osteoarthritis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 31 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 3 affected / 31 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 31 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Seasonal allergy
Serious: no
Organ System: Immune system disorders
Frequency: 1 affected / 31 at risk

Adverse event: Bronchitis
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 31 at risk

Adverse event: Cellulitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Gastroenteritis viral
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Influenza
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 31 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 31 at risk

Adverse event: Pneumonia
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Sinusitis
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 31 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 31 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 31 at risk

Adverse event: Vulvovaginal mycotic infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 31 at risk

Adverse event: Ligament sprain
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 31 at risk

Adverse event: Blood creatinine increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 31 at risk

Adverse event: Dehydration
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 31 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 31 at risk

Adverse event: Sinus headache
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 31 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 31 at risk

Adverse event: Laryngeal pain
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 31 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 31 at risk

Adverse event: Blepharitis
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Cataract
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 31 at risk

Adverse event: Cataract subcapsular
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 31 at risk

Adverse event: Conjunctival haemorrhage
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Detachment of retinal pigment epithelium
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Lacrimation increased
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 2 affected / 31 at risk

Adverse event: Refraction disorder
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 3 affected / 31 at risk

Adverse event: Retinal pigment epitheliopathy
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Visual acuity reduced
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Vitreous detachment
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 4 affected / 31 at risk

Adverse event: Vitreous floaters
Serious: no
Organ System: Eye disorders
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Intraocular pressure increased
Serious: no
Organ System: Investigations
Notes: Fellow Eye
Frequency: 1 affected / 31 at risk

Adverse event: Eye inflammation
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 31 at risk

Adverse event: Eye irritation
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 31 at risk

Adverse event: Eye pain
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 3 affected / 31 at risk

Adverse event: Lacrimation decreased
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 2 affected / 31 at risk

Adverse event: Macular degeneration
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 2 affected / 31 at risk

Adverse event: Maculopathy
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 31 at risk

Adverse event: Photopsia
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 3 affected / 31 at risk

Adverse event: Punctate keratitis
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 2 affected / 31 at risk

Adverse event: Subretinal fibrosis
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 2 affected / 31 at risk

Adverse event: Vision blurred
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 1 affected / 31 at risk

Adverse event: Visual impairment
Serious: no
Organ System: Eye disorders
Notes: Study Eye
Frequency: 3 affected / 31 at risk