Study: NCT01825512

Adverse event: Testicular injury
Serious: yes
Organ System: Injury, poisoning and procedural complications
Notes: testicular injury
Frequency: 1 affected / 193 at risk

Adverse event: Splenectomy
Serious: yes
Organ System: Surgical and medical procedures
Notes: splenectomy
Frequency: 1 affected / 193 at risk

Adverse event: Agranulocytosis
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: agranulocytosis
Frequency: 3 affected / 193 at risk

Adverse event: Neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: neutropenia
Frequency: 2 affected / 193 at risk

Adverse event: Seizure
Serious: yes
Organ System: Nervous system disorders
Notes: seizure
Frequency: 1 affected / 193 at risk

Adverse event: Pyrexia
Serious: yes
Organ System: General disorders
Notes: pyrexia
Frequency: 1 affected / 193 at risk

Adverse event: Hypertransaminasaemia
Serious: yes
Organ System: Hepatobiliary disorders
Notes: hypertransaminasaemia
Frequency: 2 affected / 193 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Notes: pneumonia
Frequency: 2 affected / 193 at risk

Adverse event: Urinary tract infection
Serious: yes
Organ System: Infections and infestations
Notes: urinary tract infection
Frequency: 1 affected / 193 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: cough
Frequency: 15 affected / 193 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 18 affected / 193 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 28 affected / 193 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: General disorders
Frequency: 20 affected / 193 at risk

Adverse event: Vomiting
Serious: no
Organ System: General disorders
Frequency: 33 affected / 193 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 23 affected / 193 at risk

Adverse event: Pharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 15 affected / 193 at risk

Adverse event: sickle cell anaemia with crisis subjects affected/exposed
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: sickle cell anaemia with crisis subjects affected/exposed
Frequency: 2 affected / 197 at risk

Adverse event: Pyrexia
Serious: yes
Organ System: General disorders
Notes: pyrexia
Frequency: 1 affected / 197 at risk

Adverse event: Chest pain
Serious: yes
Organ System: General disorders
Notes: chest pain
Frequency: 2 affected / 197 at risk

Adverse event: Gait disturbance
Serious: yes
Organ System: General disorders
Notes: gait disturbance
Frequency: 1 affected / 197 at risk

Adverse event: Diarrhoea
Serious: yes
Organ System: Gastrointestinal disorders
Notes: diarrhoea
Frequency: 1 affected / 197 at risk

Adverse event: Hypertransaminasaemia
Serious: yes
Organ System: Hepatobiliary disorders
Notes: hypertransaminasaemia
Frequency: 1 affected / 197 at risk

Adverse event: Acute kidney injury
Serious: yes
Organ System: Renal and urinary disorders
Notes: acute kidney injury
Frequency: 2 affected / 197 at risk

Adverse event: Pain in extremity
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: pain in extremity
Frequency: 1 affected / 197 at risk

Adverse event: Gastroenteritis
Serious: yes
Organ System: Infections and infestations
Notes: gastroenteritis
Frequency: 1 affected / 197 at risk

Adverse event: Meningitis meningococcal
Serious: yes
Organ System: Infections and infestations
Notes: meningitis meningococcal
Frequency: 1 affected / 197 at risk

Adverse event: Herpangina
Serious: yes
Organ System: Infections and infestations
Notes: herpangina
Frequency: 1 affected / 197 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Notes: pneumonia
Frequency: 1 affected / 197 at risk

Adverse event: Subcutaneous abscess
Serious: yes
Organ System: Infections and infestations
Notes: subcutaneous abscess
Frequency: 1 affected / 197 at risk

Adverse event: Urinary tract infection
Serious: yes
Organ System: Infections and infestations
Notes: urinary tract infection
Frequency: 1 affected / 197 at risk

Adverse event: Herpes virus infection
Serious: yes
Organ System: Infections and infestations
Notes: herpes virus infection
Frequency: 1 affected / 197 at risk

Adverse event: Impetigo
Serious: yes
Organ System: Infections and infestations
Notes: impetigo
Frequency: 1 affected / 197 at risk

Adverse event: Upper respiratory tract infection
Serious: yes
Organ System: Infections and infestations
Notes: upper respiratory tract infection
Frequency: 1 affected / 197 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: cough
Frequency: 16 affected / 197 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 11 affected / 197 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 32 affected / 197 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: General disorders
Frequency: 8 affected / 197 at risk

Adverse event: Vomiting
Serious: no
Organ System: General disorders
Frequency: 8 affected / 197 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 5 affected / 197 at risk

Adverse event: Pharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 9 affected / 197 at risk