Study: NCT00002525

Adverse event: Leukopenia
Serious: yes
Organ System: Investigations
Frequency: 3 affected / 418 at risk

Adverse event: Granulocytopenia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 418 at risk

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 22 affected / 418 at risk

Adverse event: Infection
Serious: yes
Organ System: Infections and infestations
Frequency: 9 affected / 418 at risk

Adverse event: Nausea/Vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 418 at risk

Adverse event: Vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 6 affected / 418 at risk

Adverse event: Diarrhoea
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 14 affected / 418 at risk

Adverse event: Stomatitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 11 affected / 418 at risk

Adverse event: Liver
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 2 affected / 418 at risk

Adverse event: Pulmonary
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 418 at risk

Adverse event: Cardiac
Serious: yes
Organ System: Cardiac disorders
Frequency: 9 affected / 418 at risk

Adverse event: Hypertension
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 418 at risk

Adverse event: Skin
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 418 at risk

Adverse event: Neuro-motor
Serious: yes
Organ System: Nervous system disorders
Frequency: 6 affected / 418 at risk

Adverse event: Neuro-psych
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 418 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Investigations
Frequency: 25 affected / 418 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Investigations
Frequency: 24 affected / 418 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 209 affected / 418 at risk

Adverse event: Fever (No Infection)
Serious: no
Organ System: General disorders
Frequency: 45 affected / 418 at risk

Adverse event: Nausea/vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 116 affected / 418 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 60 affected / 418 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 67 affected / 418 at risk

Adverse event: Stomatitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 71 affected / 418 at risk

Adverse event: Skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 39 affected / 418 at risk

Adverse event: Neuro-clinical
Serious: no
Organ System: Nervous system disorders
Frequency: 21 affected / 418 at risk

Adverse event: Neuro-motor
Serious: no
Organ System: Nervous system disorders
Frequency: 6 affected / 418 at risk

Adverse event: Neuro-psych
Serious: no
Organ System: Nervous system disorders
Frequency: 9 affected / 418 at risk

Adverse event: Leukopenia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 422 at risk

Adverse event: Neuro-sensory
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 422 at risk

Adverse event: Others
Serious: yes
Organ System: General disorders
Frequency: 2 affected / 422 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Investigations
Frequency: 2 affected / 422 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 7 affected / 422 at risk

Adverse event: Fever (No Infection)
Serious: no
Organ System: General disorders
Frequency: 1 affected / 422 at risk

Adverse event: Nausea/vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 422 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 422 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 422 at risk

Adverse event: Stomatitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 422 at risk

Adverse event: Skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 422 at risk

Adverse event: Neuro-clinical
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 422 at risk

Adverse event: Neuro-psych
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 422 at risk

Adverse event: Leukopenia
Serious: yes
Organ System: Investigations
Frequency: 23 affected / 171 at risk

Adverse event: Granulocytopenia
Serious: yes
Organ System: Investigations
Frequency: 4 affected / 171 at risk

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 171 at risk

Adverse event: Infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 171 at risk

Adverse event: Nausea/Vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 8 affected / 171 at risk

Adverse event: Vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 171 at risk

Adverse event: Diarrhoea
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 20 affected / 171 at risk

Adverse event: Stomatitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 6 affected / 171 at risk

Adverse event: Liver
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 5 affected / 171 at risk

Adverse event: Pulmonary
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 171 at risk

Adverse event: Cardiac
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 171 at risk

Adverse event: Hypertension
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 171 at risk

Adverse event: Skin
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 171 at risk

Adverse event: Neuro-sensory
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 171 at risk

Adverse event: Neuro-motor
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 171 at risk

Adverse event: Neuro-psych
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 171 at risk

Adverse event: Others
Serious: yes
Organ System: General disorders
Frequency: 7 affected / 171 at risk

Adverse event: Alopecia
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 171 at risk

Adverse event: Phlebitis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 5 affected / 171 at risk

Adverse event: Neuro-clinical
Serious: yes
Organ System: Nervous system disorders
Frequency: 6 affected / 171 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Investigations
Frequency: 78 affected / 171 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Investigations
Frequency: 66 affected / 171 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 105 affected / 171 at risk

Adverse event: Fever (No Infection)
Serious: no
Organ System: General disorders
Frequency: 15 affected / 171 at risk

Adverse event: Nausea/vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 94 affected / 171 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 45 affected / 171 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 74 affected / 171 at risk

Adverse event: Stomatitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 59 affected / 171 at risk

Adverse event: Skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 73 affected / 171 at risk

Adverse event: Neuro-clinical
Serious: no
Organ System: Nervous system disorders
Frequency: 84 affected / 171 at risk

Adverse event: Infection
Serious: no
Organ System: Infections and infestations
Frequency: 33 affected / 171 at risk

Adverse event: Neuro-motor
Serious: no
Organ System: Nervous system disorders
Frequency: 33 affected / 171 at risk

Adverse event: Neuro-psych
Serious: no
Organ System: Nervous system disorders
Frequency: 17 affected / 171 at risk

Adverse event: Leukopenia
Serious: yes
Organ System: Investigations
Frequency: 8 affected / 61 at risk

Adverse event: Granulocytopenia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 61 at risk

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 61 at risk

Adverse event: Infection
Serious: yes
Organ System: Infections and infestations
Frequency: 3 affected / 61 at risk

Adverse event: Nausea/Vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 61 at risk

Adverse event: Vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 61 at risk

Adverse event: Diarrhoea
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 15 affected / 61 at risk

Adverse event: Stomatitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 9 affected / 61 at risk

Adverse event: Liver
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 61 at risk

Adverse event: Pulmonary
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 61 at risk

Adverse event: Cardiac
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 61 at risk

Adverse event: Skin
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 61 at risk

Adverse event: Neuro-motor
Serious: yes
Organ System: Nervous system disorders
Frequency: 4 affected / 61 at risk

Adverse event: Neuro-psych
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 61 at risk

Adverse event: Others
Serious: yes
Organ System: General disorders
Frequency: 6 affected / 61 at risk

Adverse event: Phlebitis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 61 at risk

Adverse event: Neuro-clinical
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 61 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Investigations
Frequency: 32 affected / 61 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Investigations
Frequency: 14 affected / 61 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 43 affected / 61 at risk

Adverse event: Fever (No Infection)
Serious: no
Organ System: General disorders
Frequency: 7 affected / 61 at risk

Adverse event: Nausea/vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 27 affected / 61 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 11 affected / 61 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 27 affected / 61 at risk

Adverse event: Stomatitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 20 affected / 61 at risk

Adverse event: Skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 24 affected / 61 at risk

Adverse event: Neuro-clinical
Serious: no
Organ System: Nervous system disorders
Frequency: 18 affected / 61 at risk

Adverse event: Infection
Serious: no
Organ System: Infections and infestations
Frequency: 9 affected / 61 at risk

Adverse event: Neuro-motor
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 61 at risk

Adverse event: Neuro-psych
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 61 at risk