Study: NCT01594281

Adverse event: ACUTE MYOCARDIAL INFARCTION (Non-ocular)
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 35 at risk

Adverse event: DIABETIC RETINOPATHY (Left eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: RETINAL HAEMORRHAGE (Both eyes)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: RETINAL HAEMORRHAGE (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: RETINAL NEOVASCULARISATION (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: VISUAL ACUITY REDUCED (Left eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: VITREOUS ADHESIONS (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: VITREOUS HAEMORRHAGE (Left eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: VITREOUS HAEMORRHAGE (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: GENERAL PHYSICAL HEALTH DETERIORATION (Non-ocular)
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 35 at risk

Adverse event: GASTROENTERITIS (Non-ocular)
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 35 at risk

Adverse event: OSTEOMYELITIS (Non-ocular)
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 35 at risk

Adverse event: POSTOPERATIVE WOUND INFECTION (Non-ocular)
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 35 at risk

Adverse event: HUMERUS FRACTURE (Non-ocular)
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 35 at risk

Adverse event: DEHYDRATION (Non-ocular)
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 35 at risk

Adverse event: HYPOGLYCAEMIA (Non-ocular)
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 35 at risk

Adverse event: INTERVERTEBRAL DISC PROTRUSION (Non-ocular)
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 35 at risk

Adverse event: CHRONIC LYMPHOCYTIC LEUKAEMIA (Non-ocular)
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 35 at risk

Adverse event: CEREBROVASCULAR ACCIDENT (Non-ocular)
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 35 at risk

Adverse event: PREGNANCY (Non-ocular)
Serious: yes
Organ System: Pregnancy, puerperium and perinatal conditions
Frequency: 1 affected / 35 at risk

Adverse event: BLEPHARITIS (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: CATARACT (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: CATARACT (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: CONJUNCTIVAL HAEMORRHAGE (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: CONJUNCTIVAL HAEMORRHAGE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: CONJUNCTIVITIS ALLERGIC (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: CORNEAL EROSION (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: CORNEAL EROSION (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: DIABETIC RETINOPATHY (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 35 at risk

Adverse event: DIABETIC RETINOPATHY (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 35 at risk

Adverse event: DRY EYE (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: EYE PAIN (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: EYE PAIN (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: FOREIGN BODY SENSATION IN EYES (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: FOREIGN BODY SENSATION IN EYES (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: LACRIMATION INCREASED (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: MACULAR FIBROSIS (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: MACULAR FIBROSIS (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: MACULAR OEDEMA (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 35 at risk

Adverse event: MACULAR OEDEMA (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: OCULAR DISCOMFORT (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: OCULAR HYPERAEMIA (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 35 at risk

Adverse event: OCULAR HYPERAEMIA (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: RETINAL EXUDATES (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: RETINAL HAEMORRHAGE (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 35 at risk

Adverse event: RETINAL HAEMORRHAGE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: RETINAL ISCHAEMIA (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: RETINAL NEOVASCULARISATION (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: RETINAL NEOVASCULARISATION (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 35 at risk

Adverse event: RETINAL NEOVASCULARISATION (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 12 affected / 35 at risk

Adverse event: VISUAL ACUITY REDUCED (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: VISUAL ACUITY REDUCED (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 35 at risk

Adverse event: VISUAL ACUITY REDUCED (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 35 at risk

Adverse event: VISUAL IMPAIRMENT (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: VITREOUS ADHESIONS (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: VITREOUS FLOATERS (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: VITREOUS HAEMORRHAGE (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 35 at risk

Adverse event: VITREOUS HAEMORRHAGE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 35 at risk

Adverse event: DIARRHOEA (Non-ocular)
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 35 at risk

Adverse event: NAUSEA (Non-ocular)
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 35 at risk

Adverse event: TOOTHACHE (Non-ocular)
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 35 at risk

Adverse event: VOMITING (Non-ocular)
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 35 at risk

Adverse event: BRONCHITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 35 at risk

Adverse event: GASTROENTERITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 35 at risk

Adverse event: HORDEOLUM (Left eye)
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 35 at risk

Adverse event: NASOPHARYNGITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 7 affected / 35 at risk

Adverse event: RHINITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 35 at risk

Adverse event: FALL (Non-ocular)
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 35 at risk

Adverse event: FOOT FRACTURE (Non-ocular)
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 35 at risk

Adverse event: SCRATCH (Non-ocular)
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 35 at risk

Adverse event: BLOOD TRIGLYCERIDES INCREASED (Non-ocular)
Serious: no
Organ System: Investigations
Frequency: 1 affected / 35 at risk

Adverse event: GLYCOSYLATED HAEMOGLOBIN INCREASED (Non-ocular)
Serious: no
Organ System: Investigations
Frequency: 4 affected / 35 at risk

Adverse event: INTRAOCULAR PRESSURE INCREASED (Left eye)
Serious: no
Organ System: Investigations
Frequency: 1 affected / 35 at risk

Adverse event: INTRAOCULAR PRESSURE INCREASED (Right eye)
Serious: no
Organ System: Investigations
Frequency: 1 affected / 35 at risk

Adverse event: ARTHRITIS (Non-ocular)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 35 at risk

Adverse event: PAIN IN EXTREMITY (Non-ocular)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 35 at risk

Adverse event: HEADACHE (Non-ocular)
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 35 at risk

Adverse event: COUGH (Non-ocular)
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 35 at risk

Adverse event: HYPERTENSION (Non-ocular)
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 35 at risk

Adverse event: RETINAL ISCHAEMIA (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: VITAMIN D DEFICIENCY (Non-ocular)
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 35 at risk

Adverse event: BACK PAIN (Non-ocular)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 35 at risk

Adverse event: ATRIAL FIBRILLATION (Non-ocular)
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 35 at risk

Adverse event: SUDDEN HEARING LOSS (Non-ocular)
Serious: yes
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 35 at risk

Adverse event: CATARACT (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: DIABETIC RETINOPATHY (Left eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: DIABETIC RETINOPATHY (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: OPEN ANGLE GLAUCOMA (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: VITREOUS HAEMORRHAGE (Left eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: VITREOUS HAEMORRHAGE (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: NON-CARDIAC CHEST PAIN (Non-ocular)
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 35 at risk

Adverse event: SPINAL FRACTURE (Non-ocular)
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 35 at risk

Adverse event: PREGNANCY (Non-ocular)
Serious: yes
Organ System: Pregnancy, puerperium and perinatal conditions
Frequency: 1 affected / 35 at risk

Adverse event: DIABETIC FOOT (Non-ocular)
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 35 at risk

Adverse event: ABNORMAL SENSATION IN EYE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: CATARACT (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: CATARACT (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: CORNEAL EROSION (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 35 at risk

Adverse event: CYSTOID MACULAR OEDEMA (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: DIABETIC RETINAL OEDEMA (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: DIABETIC RETINOPATHY (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: DIABETIC RETINOPATHY (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: DIABETIC RETINOPATHY (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: DRY EYE (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: EYE IRRITATION (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: EYE PAIN (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: EYE PAIN (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: GLARE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: IRIS NEOVASCULARISATION (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: LACRIMATION INCREASED (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: MACULAR FIBROSIS (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: MACULAR FIBROSIS (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: MACULAR OEDEMA (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: MACULAR OEDEMA (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 35 at risk

Adverse event: MACULAR OEDEMA (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 8 affected / 35 at risk

Adverse event: PUNCTATE KERATITIS (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: RETINAL CYST (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: RETINAL EXUDATES (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: RETINAL HAEMORRHAGE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: RETINAL NEOVASCULARISATION (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: RETINAL NEOVASCULARISATION (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 35 at risk

Adverse event: RETINAL NEOVASCULARISATION (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: VISION BLURRED (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: VISUAL ACUITY REDUCED (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: VISUAL ACUITY REDUCED (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 35 at risk

Adverse event: VISUAL ACUITY REDUCED (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 9 affected / 35 at risk

Adverse event: VISUAL IMPAIRMENT (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: VITREOUS ADHESIONS (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: VITREOUS DETACHMENT (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 35 at risk

Adverse event: VITREOUS FLOATERS (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 35 at risk

Adverse event: VITREOUS HAEMORRHAGE (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 35 at risk

Adverse event: VITREOUS HAEMORRHAGE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 35 at risk

Adverse event: DIARRHOEA (Non-ocular)
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 35 at risk

Adverse event: VOMITING (Non-ocular)
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 35 at risk

Adverse event: HORDEOLUM (Left eye)
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 35 at risk

Adverse event: INFLUENZA (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 35 at risk

Adverse event: NASOPHARYNGITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 12 affected / 35 at risk

Adverse event: RHINITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 35 at risk

Adverse event: SINUSITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 35 at risk

Adverse event: FALL (Non-ocular)
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 3 affected / 35 at risk

Adverse event: PROCEDURAL PAIN (Left eye)
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 35 at risk

Adverse event: BLOOD PRESSURE INCREASED (Non-ocular)
Serious: no
Organ System: Investigations
Frequency: 1 affected / 35 at risk

Adverse event: HEADACHE (Non-ocular)
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 35 at risk

Adverse event: COUGH (Non-ocular)
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 35 at risk

Adverse event: HYPERTENSION (Non-ocular)
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 35 at risk

Adverse event: BACK PAIN (Non-ocular)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 35 at risk

Adverse event: CORONARY ARTERY DISEASE (Non-ocular)
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 36 at risk

Adverse event: CATARACT (Left eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 36 at risk

Adverse event: DIABETIC RETINAL OEDEMA (Left eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 36 at risk

Adverse event: DIABETIC RETINAL OEDEMA (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 36 at risk

Adverse event: DIABETIC RETINOPATHY (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: MACULAR OEDEMA (Left eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 36 at risk

Adverse event: RETINAL DETACHMENT (Left eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 36 at risk

Adverse event: VITREOUS HAEMORRHAGE (Left eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 36 at risk

Adverse event: INFECTED SKIN ULCER (Non-ocular)
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 36 at risk

Adverse event: LOCALISED INFECTION (Non-ocular)
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 36 at risk

Adverse event: KIDNEY CONTUSION (Non-ocular)
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 36 at risk

Adverse event: RIB FRACTURE (Non-ocular)
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 36 at risk

Adverse event: BLOOD GLUCOSE FLUCTUATION (Non-ocular)
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 36 at risk

Adverse event: DIABETES MELLITUS (Non-ocular)
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 36 at risk

Adverse event: HYPERGLYCAEMIA (Non-ocular)
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 36 at risk

Adverse event: OBESITY (Non-ocular)
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 36 at risk

Adverse event: OSTEITIS (Non-ocular)
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 36 at risk

Adverse event: CEREBROVASCULAR ACCIDENT (Non-ocular)
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 36 at risk

Adverse event: DIABETIC FOOT (Non-ocular)
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 36 at risk

Adverse event: DIABETIC MICROANGIOPATHY (Non-ocular)
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 36 at risk

Adverse event: PERIPHERAL ARTERIAL OCCLUSIVE DISEASE (Non-ocular)
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 36 at risk

Adverse event: PERIPHERAL VENOUS DISEASE (Non-ocular)
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 36 at risk

Adverse event: BLEPHARITIS (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: CATARACT (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 36 at risk

Adverse event: CONJUNCTIVAL HAEMORRHAGE (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 36 at risk

Adverse event: CONJUNCTIVAL HAEMORRHAGE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: CONJUNCTIVITIS ALLERGIC (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 36 at risk

Adverse event: CORNEAL EROSION (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 36 at risk

Adverse event: CORNEAL EROSION (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 36 at risk

Adverse event: CYSTOID MACULAR OEDEMA (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: DIABETIC RETINAL OEDEMA (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: DIABETIC RETINAL OEDEMA (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 36 at risk

Adverse event: DIABETIC RETINOPATHY (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: DIABETIC RETINOPATHY (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 36 at risk

Adverse event: DIABETIC RETINOPATHY (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 36 at risk

Adverse event: DRY EYE (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: EYE IRRITATION (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 36 at risk

Adverse event: EYE IRRITATION (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 36 at risk

Adverse event: EYE PAIN (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 36 at risk

Adverse event: EYE PAIN (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 36 at risk

Adverse event: FOREIGN BODY SENSATION IN EYES (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: IRIS NEOVASCULARISATION (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: IRIS NEOVASCULARISATION (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 36 at risk

Adverse event: LACRIMATION INCREASED (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 36 at risk

Adverse event: LACRIMATION INCREASED (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: MACULAR FIBROSIS (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 36 at risk

Adverse event: MACULAR OEDEMA (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: MACULAR OEDEMA (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 36 at risk

Adverse event: MACULAR OEDEMA (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 36 at risk

Adverse event: OCULAR HYPERAEMIA (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 36 at risk

Adverse event: OCULAR HYPERAEMIA (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 36 at risk

Adverse event: RETINAL HAEMORRHAGE (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 36 at risk

Adverse event: RETINAL HAEMORRHAGE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 36 at risk

Adverse event: RETINAL ISCHAEMIA (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: RETINAL NEOVASCULARISATION (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: RETINAL NEOVASCULARISATION (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 9 affected / 36 at risk

Adverse event: RETINAL NEOVASCULARISATION (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 10 affected / 36 at risk

Adverse event: VISION BLURRED (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 36 at risk

Adverse event: VISUAL ACUITY REDUCED (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: VISUAL ACUITY REDUCED (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 12 affected / 36 at risk

Adverse event: VISUAL ACUITY REDUCED (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 36 at risk

Adverse event: VISUAL IMPAIRMENT (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: VITREOUS FLOATERS (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: VITREOUS HAEMORRHAGE (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 36 at risk

Adverse event: VITREOUS HAEMORRHAGE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 36 at risk

Adverse event: DIARRHOEA (Non-ocular)
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 36 at risk

Adverse event: TOOTHACHE (Non-ocular)
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 36 at risk

Adverse event: GASTROENTERITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 36 at risk

Adverse event: INFLUENZA (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 36 at risk

Adverse event: NASOPHARYNGITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 9 affected / 36 at risk

Adverse event: RHINITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 36 at risk

Adverse event: SINUSITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 36 at risk

Adverse event: CONTUSION (Non-ocular)
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 36 at risk

Adverse event: PROCEDURAL PAIN (Both eyes)
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 3 affected / 36 at risk

Adverse event: PROCEDURAL PAIN (Left eye)
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 4 affected / 36 at risk

Adverse event: BLOOD CHOLESTEROL INCREASED (Non-ocular)
Serious: no
Organ System: Investigations
Frequency: 1 affected / 36 at risk

Adverse event: GLYCOSYLATED HAEMOGLOBIN INCREASED (Non-ocular)
Serious: no
Organ System: Investigations
Frequency: 6 affected / 36 at risk

Adverse event: INTRAOCULAR PRESSURE INCREASED (Left eye)
Serious: no
Organ System: Investigations
Frequency: 3 affected / 36 at risk

Adverse event: INTRAOCULAR PRESSURE INCREASED (Right eye)
Serious: no
Organ System: Investigations
Frequency: 2 affected / 36 at risk

Adverse event: HYPERCHOLESTEROLAEMIA (Non-ocular)
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 36 at risk

Adverse event: ARTHRITIS (Non-ocular)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 36 at risk

Adverse event: PAIN IN EXTREMITY (Non-ocular)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 36 at risk

Adverse event: HEADACHE (Non-ocular)
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 36 at risk

Adverse event: COUGH (Non-ocular)
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 36 at risk

Adverse event: DIABETIC FOOT (Non-ocular)
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 36 at risk

Adverse event: RETINAL ISCHAEMIA (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 36 at risk

Adverse event: ANTERIOR CHAMBER DISORDER (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: CATARACT (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: DIABETIC RETINAL OEDEMA (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: GLAUCOMA (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: MACULAR FIBROSIS (Left eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: MACULAR FIBROSIS (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: RETINAL HAEMORRHAGE (Both eyes)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: ABDOMINAL PAIN (Non-ocular)
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 28 at risk

Adverse event: FRACTURED COCCYX (Non-ocular)
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 28 at risk

Adverse event: HYPHAEMA (Right eye)
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 28 at risk

Adverse event: DIABETES MELLITUS (Non-ocular)
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 28 at risk

Adverse event: HYPERGLYCAEMIA (Non-ocular)
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 28 at risk

Adverse event: CHRONIC KIDNEY DISEASE (Non-ocular)
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 28 at risk

Adverse event: CATARACT (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 28 at risk

Adverse event: CONJUNCTIVAL HAEMORRHAGE (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: CONJUNCTIVAL HAEMORRHAGE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: DIABETIC RETINOPATHY (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: DIABETIC RETINOPATHY (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 28 at risk

Adverse event: DIABETIC RETINOPATHY (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 28 at risk

Adverse event: DRY EYE (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: EYE PAIN (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: GLARE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: MACULAR FIBROSIS (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: MACULAR OEDEMA (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 28 at risk

Adverse event: MACULAR OEDEMA (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 28 at risk

Adverse event: MACULAR OEDEMA (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 28 at risk

Adverse event: RETINAL HAEMORRHAGE (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: RETINAL HAEMORRHAGE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: RETINAL ISCHAEMIA (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: RETINAL NEOVASCULARISATION (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 8 affected / 28 at risk

Adverse event: RETINAL NEOVASCULARISATION (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 28 at risk

Adverse event: VISUAL ACUITY REDUCED (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: VISUAL ACUITY REDUCED (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 28 at risk

Adverse event: VISUAL ACUITY REDUCED (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 28 at risk

Adverse event: VISUAL IMPAIRMENT (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: VITREOUS ADHESIONS (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: VITREOUS HAEMORRHAGE (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 28 at risk

Adverse event: VITREOUS HAEMORRHAGE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 28 at risk

Adverse event: NAUSEA (Non-ocular)
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 28 at risk

Adverse event: HORDEOLUM (Left eye)
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 28 at risk

Adverse event: NASOPHARYNGITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 28 at risk

Adverse event: CONTUSION (Non-ocular)
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 28 at risk

Adverse event: BLOOD CHOLESTEROL INCREASED (Non-ocular)
Serious: no
Organ System: Investigations
Frequency: 3 affected / 28 at risk

Adverse event: BLOOD PRESSURE INCREASED (Non-ocular)
Serious: no
Organ System: Investigations
Frequency: 2 affected / 28 at risk

Adverse event: BLOOD TRIGLYCERIDES INCREASED (Non-ocular)
Serious: no
Organ System: Investigations
Frequency: 2 affected / 28 at risk

Adverse event: GLYCOSYLATED HAEMOGLOBIN INCREASED (Non-ocular)
Serious: no
Organ System: Investigations
Frequency: 3 affected / 28 at risk

Adverse event: PAIN IN EXTREMITY (Non-ocular)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 28 at risk

Adverse event: HYPERTENSION (Non-ocular)
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 28 at risk

Adverse event: RETINAL ISCHAEMIA (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 28 at risk

Adverse event: BACK PAIN (Non-ocular)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 28 at risk

Adverse event: HEART VALVE STENOSIS (Non-ocular)
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 20 at risk

Adverse event: DIABETIC RETINOPATHY (Left eye)
Serious: yes
Organ System: Eye disorders
Frequency: 2 affected / 20 at risk

Adverse event: DIABETIC RETINOPATHY (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 20 at risk

Adverse event: TENDON RUPTURE (Non-ocular)
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 20 at risk

Adverse event: BLOOD GLUCOSE FLUCTUATION (Non-ocular)
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 20 at risk

Adverse event: PSYCHIATRIC DECOMPENSATION (Non-ocular)
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 20 at risk

Adverse event: HYPOTHYROIDISM (Non-ocular)
Serious: no
Organ System: Endocrine disorders
Frequency: 2 affected / 20 at risk

Adverse event: CONJUNCTIVAL HAEMORRHAGE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 20 at risk

Adverse event: LACRIMATION INCREASED (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 20 at risk

Adverse event: MACULAR OEDEMA (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 20 at risk

Adverse event: MACULAR OEDEMA (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 20 at risk

Adverse event: RETINAL NEOVASCULARISATION (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 20 at risk

Adverse event: VISUAL ACUITY REDUCED (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 20 at risk

Adverse event: VISUAL ACUITY REDUCED (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 20 at risk

Adverse event: VITREOUS HAEMORRHAGE (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 20 at risk

Adverse event: VITREOUS HAEMORRHAGE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 20 at risk

Adverse event: NASOPHARYNGITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 20 at risk

Adverse event: BLOOD CHOLESTEROL INCREASED (Non-ocular)
Serious: no
Organ System: Investigations
Frequency: 1 affected / 20 at risk

Adverse event: BLOOD TRIGLYCERIDES INCREASED (Non-ocular)
Serious: no
Organ System: Investigations
Frequency: 2 affected / 20 at risk

Adverse event: GLYCOSYLATED HAEMOGLOBIN INCREASED (Non-ocular)
Serious: no
Organ System: Investigations
Frequency: 2 affected / 20 at risk

Adverse event: HYPERTENSION (Non-ocular)
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 20 at risk

Adverse event: CONGESTIVE CARDIOMYOPATHY (Non-ocular)
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 25 at risk

Adverse event: DIABETIC RETINOPATHY (Left eye)
Serious: yes
Organ System: Eye disorders
Frequency: 2 affected / 25 at risk

Adverse event: DIABETIC RETINOPATHY (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: RETINAL NEOVASCULARISATION (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: VITREOUS HAEMORRHAGE (Left eye)
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: VITREOUS HAEMORRHAGE (Right eye)
Serious: yes
Organ System: Eye disorders
Frequency: 2 affected / 25 at risk

Adverse event: CHRONIC GASTRITIS (Non-ocular)
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 25 at risk

Adverse event: DENTAL CYST (Non-ocular)
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 25 at risk

Adverse event: DIARRHOEA (Non-ocular)
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 25 at risk

Adverse event: UMBILICAL HERNIA (Non-ocular)
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 25 at risk

Adverse event: CHEST PAIN (Non-ocular)
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 25 at risk

Adverse event: PERIPHERAL SWELLING (Non-ocular)
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 25 at risk

Adverse event: GASTROENTERITIS (Non-ocular)
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 25 at risk

Adverse event: MENINGITIS (Non-ocular)
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 25 at risk

Adverse event: OSTEOMYELITIS CHRONIC (Non-ocular)
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 25 at risk

Adverse event: MENISCUS INJURY (Non-ocular)
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 25 at risk

Adverse event: DIABETES MELLITUS (Non-ocular)
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 25 at risk

Adverse event: OBESITY (Non-ocular)
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 25 at risk

Adverse event: GASTRIC CANCER (Non-ocular)
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 25 at risk

Adverse event: DIZZINESS (Non-ocular)
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 25 at risk

Adverse event: COUGH (Non-ocular)
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 25 at risk

Adverse event: DYSPNOEA (Non-ocular)
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 25 at risk

Adverse event: COLD SWEAT (Non-ocular)
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 25 at risk

Adverse event: HYPERTENSION (Non-ocular)
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 25 at risk

Adverse event: PERIPHERAL ARTERY OCCLUSION (Non-ocular)
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 25 at risk

Adverse event: CATARACT (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: CATARACT (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: DIABETIC RETINAL OEDEMA (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: DIABETIC RETINOPATHY (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 25 at risk

Adverse event: DRY EYE (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: IRIS NEOVASCULARISATION (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: MACULAR OEDEMA (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: MACULAR OEDEMA (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 25 at risk

Adverse event: MACULAR OEDEMA (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 25 at risk

Adverse event: RETINAL CYST (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: RETINAL HAEMORRHAGE (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: RETINAL HAEMORRHAGE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 25 at risk

Adverse event: RETINAL ISCHAEMIA (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: RETINAL NEOVASCULARISATION (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 25 at risk

Adverse event: RETINAL NEOVASCULARISATION (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 25 at risk

Adverse event: RETINAL NEOVASCULARISATION (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 25 at risk

Adverse event: VISUAL ACUITY REDUCED (Both eyes)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: VISUAL ACUITY REDUCED (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: VISUAL ACUITY REDUCED (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: VISUAL IMPAIRMENT (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: VITREOUS FLOATERS (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: VITREOUS HAEMORRHAGE (Left eye)
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 25 at risk

Adverse event: VITREOUS HAEMORRHAGE (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 25 at risk

Adverse event: NAUSEA (Non-ocular)
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 25 at risk

Adverse event: VOMITING (Non-ocular)
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 25 at risk

Adverse event: BRONCHITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 25 at risk

Adverse event: NASOPHARYNGITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 25 at risk

Adverse event: SINUSITIS (Non-ocular)
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 25 at risk

Adverse event: RIB FRACTURE (Non-ocular)
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 25 at risk

Adverse event: ROAD TRAFFIC ACCIDENT (Non-ocular)
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 25 at risk

Adverse event: BLOOD TRIGLYCERIDES INCREASED (Non-ocular)
Serious: no
Organ System: Investigations
Frequency: 1 affected / 25 at risk

Adverse event: GLYCOSYLATED HAEMOGLOBIN INCREASED (Non-ocular)
Serious: no
Organ System: Investigations
Frequency: 1 affected / 25 at risk

Adverse event: HYPERCHOLESTEROLAEMIA (Non-ocular)
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 25 at risk

Adverse event: PAIN IN EXTREMITY (Non-ocular)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 25 at risk

Adverse event: HEADACHE (Non-ocular)
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 25 at risk

Adverse event: HYPERTENSION (Non-ocular)
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 25 at risk

Adverse event: RETINAL ISCHAEMIA (Right eye)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 25 at risk

Adverse event: BACK PAIN (Non-ocular)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 25 at risk