Study: NCT03652051

Adverse event: Application site pain
Serious: no
Organ System: Eye disorders
Notes: Application site pain
Frequency: 1 affected / 9 at risk

Adverse event: Foreign body sensation
Serious: no
Organ System: Eye disorders
Notes: Foreign body sensation
Frequency: 1 affected / 9 at risk

Adverse event: Administration site reaction
Serious: no
Organ System: Eye disorders
Notes: Administration site reaction
Frequency: 1 affected / 9 at risk

Adverse event: Application site pain
Serious: no
Organ System: Eye disorders
Notes: Application site pain
Frequency: 12 affected / 27 at risk

Adverse event: Lacrimation increased
Serious: no
Organ System: Eye disorders
Notes: Lacrimation increased
Frequency: 4 affected / 27 at risk

Adverse event: Punctate keratitis
Serious: no
Organ System: Eye disorders
Notes: Punctate keratitis
Frequency: 1 affected / 27 at risk

Adverse event: Vital dye staining cornea present
Serious: no
Organ System: Eye disorders
Notes: Vital dye staining cornea present
Frequency: 1 affected / 27 at risk

Adverse event: Eye pain
Serious: no
Organ System: Eye disorders
Notes: Eye pain
Frequency: 3 affected / 27 at risk

Adverse event: Eye irritation
Serious: no
Organ System: Eye disorders
Notes: Eye irritation
Frequency: 7 affected / 27 at risk

Adverse event: Application site reaction
Serious: no
Organ System: Eye disorders
Notes: Application site reaction
Frequency: 1 affected / 27 at risk

Adverse event: Foreign body sensation
Serious: no
Organ System: Eye disorders
Notes: Foreign body sensation
Frequency: 2 affected / 27 at risk

Adverse event: Administration site reaction
Serious: no
Organ System: Eye disorders
Notes: Administration site reaction
Frequency: 2 affected / 27 at risk

Adverse event: Photophobia
Serious: no
Organ System: Eye disorders
Notes: Photophobia
Frequency: 5 affected / 27 at risk

Adverse event: Application site irritation
Serious: no
Organ System: Eye disorders
Notes: Application site irritation
Frequency: 2 affected / 27 at risk

Adverse event: n intervertebral disc protrusion
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 24 at risk

Adverse event: Ocular toxicity
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 24 at risk

Adverse event: Application site pain
Serious: no
Organ System: Eye disorders
Notes: Application site pain
Frequency: 9 affected / 24 at risk

Adverse event: Lacrimation increased
Serious: no
Organ System: Eye disorders
Notes: Lacrimation increased
Frequency: 3 affected / 24 at risk

Adverse event: Vital dye staining cornea present
Serious: no
Organ System: Eye disorders
Notes: Vital dye staining cornea present
Frequency: 2 affected / 24 at risk

Adverse event: Eye pain
Serious: no
Organ System: Eye disorders
Notes: Eye pain
Frequency: 4 affected / 24 at risk

Adverse event: Eye irritation
Serious: no
Organ System: Eye disorders
Notes: Eye irritation
Frequency: 2 affected / 24 at risk

Adverse event: Application site reaction
Serious: no
Organ System: Eye disorders
Notes: Application site reaction
Frequency: 1 affected / 24 at risk

Adverse event: Foreign body sensation
Serious: no
Organ System: Eye disorders
Notes: Foreign body sensation
Frequency: 2 affected / 24 at risk

Adverse event: Administration site reaction
Serious: no
Organ System: Eye disorders
Notes: Administration site reaction
Frequency: 7 affected / 24 at risk

Adverse event: Photophobia
Serious: no
Organ System: Eye disorders
Notes: Photophobia
Frequency: 3 affected / 24 at risk

Adverse event: Application site pain
Serious: no
Organ System: Eye disorders
Notes: Application site pain
Frequency: 1 affected / 16 at risk

Adverse event: Foreign body sensation
Serious: no
Organ System: Eye disorders
Notes: Foreign body sensation
Frequency: 2 affected / 16 at risk

Adverse event: Administration site reaction
Serious: no
Organ System: Eye disorders
Notes: Administration site reaction
Frequency: 2 affected / 16 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Notes: pneumonia
Frequency: 1 affected / 82 at risk

Adverse event: Application site pain
Serious: no
Organ System: Eye disorders
Notes: Application site pain
Frequency: 14 affected / 82 at risk

Adverse event: Lacrimation increased
Serious: no
Organ System: Eye disorders
Notes: Lacrimation increased
Frequency: 9 affected / 82 at risk

Adverse event: Punctate keratitis
Serious: no
Organ System: Eye disorders
Notes: Punctate keratitis
Frequency: 8 affected / 82 at risk

Adverse event: Vital dye staining cornea present
Serious: no
Organ System: Eye disorders
Notes: Vital dye staining cornea present
Frequency: 5 affected / 82 at risk

Adverse event: Eye pain
Serious: no
Organ System: Eye disorders
Notes: Eye pain
Frequency: 5 affected / 82 at risk

Adverse event: Eye irritation
Serious: no
Organ System: Eye disorders
Notes: Eye irritation
Frequency: 4 affected / 82 at risk

Adverse event: Application site reaction
Serious: no
Organ System: Eye disorders
Notes: Application site reaction
Frequency: 4 affected / 82 at risk

Adverse event: Foreign body sensation
Serious: no
Organ System: Eye disorders
Notes: Foreign body sensation
Frequency: 4 affected / 82 at risk

Adverse event: Administration site reaction
Serious: no
Organ System: Eye disorders
Notes: Administration site reaction
Frequency: 4 affected / 82 at risk

Adverse event: Photophobia
Serious: no
Organ System: Eye disorders
Notes: Photophobia
Frequency: 4 affected / 82 at risk

Adverse event: Eye inflammation
Serious: no
Organ System: Eye disorders
Notes: Eye inflammation
Frequency: 3 affected / 82 at risk

Adverse event: Application site irritation
Serious: no
Organ System: Eye disorders
Notes: Application site irritation
Frequency: 2 affected / 82 at risk

Adverse event: Post procedural haemorrhage
Serious: yes
Organ System: Injury, poisoning and procedural complications
Notes: Post procedural haemorrhage
Frequency: 1 affected / 83 at risk

Adverse event: Application site pain
Serious: no
Organ System: Eye disorders
Notes: Application site pain
Frequency: 13 affected / 83 at risk

Adverse event: Lacrimation increased
Serious: no
Organ System: Eye disorders
Notes: Lacrimation increased
Frequency: 1 affected / 83 at risk

Adverse event: Punctate keratitis
Serious: no
Organ System: Eye disorders
Notes: Punctate keratitis
Frequency: 7 affected / 83 at risk

Adverse event: Vital dye staining cornea present
Serious: no
Organ System: Eye disorders
Notes: Vital dye staining cornea present
Frequency: 7 affected / 83 at risk

Adverse event: Eye pain
Serious: no
Organ System: Eye disorders
Notes: Eye pain
Frequency: 6 affected / 83 at risk

Adverse event: Eye irritation
Serious: no
Organ System: Eye disorders
Notes: Eye irritation
Frequency: 5 affected / 83 at risk

Adverse event: Application site reaction
Serious: no
Organ System: Eye disorders
Notes: Application site reaction
Frequency: 4 affected / 83 at risk

Adverse event: Foreign body sensation
Serious: no
Organ System: Eye disorders
Notes: Foreign body sensation
Frequency: 2 affected / 83 at risk

Adverse event: Administration site reaction
Serious: no
Organ System: Eye disorders
Notes: Administration site reaction
Frequency: 1 affected / 83 at risk

Adverse event: Photophobia
Serious: no
Organ System: Eye disorders
Notes: Photophobia
Frequency: 1 affected / 83 at risk

Adverse event: Eye inflammation
Serious: no
Organ System: Eye disorders
Notes: Eye inflammation
Frequency: 8 affected / 83 at risk

Adverse event: Application site irritation
Serious: no
Organ System: Eye disorders
Notes: Application site irritation
Frequency: 5 affected / 83 at risk

Adverse event: Pericarditis
Serious: yes
Organ System: Cardiac disorders
Notes: Pericarditis
Frequency: 1 affected / 80 at risk

Adverse event: Thyroid mass
Serious: yes
Organ System: Endocrine disorders
Notes: Thyroid mass
Frequency: 1 affected / 80 at risk

Adverse event: Punctate keratitis
Serious: no
Organ System: Eye disorders
Notes: Punctate keratitis
Frequency: 1 affected / 80 at risk

Adverse event: Vital dye staining cornea present
Serious: no
Organ System: Eye disorders
Notes: Vital dye staining cornea present
Frequency: 1 affected / 80 at risk

Adverse event: Eye pain
Serious: no
Organ System: Eye disorders
Notes: Eye pain
Frequency: 1 affected / 80 at risk

Adverse event: Eye irritation
Serious: no
Organ System: Eye disorders
Notes: Eye irritation
Frequency: 2 affected / 80 at risk

Adverse event: Foreign body sensation
Serious: no
Organ System: Eye disorders
Notes: Foreign body sensation
Frequency: 1 affected / 80 at risk

Adverse event: Photophobia
Serious: no
Organ System: Eye disorders
Notes: Photophobia
Frequency: 1 affected / 80 at risk

Adverse event: Eye inflammation
Serious: no
Organ System: Eye disorders
Notes: Eye inflammation
Frequency: 1 affected / 80 at risk