TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT00670306

Adverse event: Appendicitis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 528 at risk

Adverse event: Substance abuse
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 528 at risk

Adverse event: Haemorrhagic stroke
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 528 at risk

Adverse event: Chest pain
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 528 at risk

Adverse event: Coronary artery disease
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 528 at risk

Adverse event: rectal abcess
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 528 at risk

Adverse event: Humerus fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 528 at risk

Adverse event: Bladder transitional cell carcinoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 528 at risk

Adverse event: Chest discomfort
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 528 at risk

Adverse event: chest pain / elevated cardiac enzymes
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 528 at risk

Adverse event: peripheral artery anuerysm / aortic aneurysm
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 528 at risk

Adverse event: Small intestinal obstruction
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 528 at risk

Adverse event: Hot flush
Serious: no
Organ System: Vascular disorders
Frequency: 49 affected / 528 at risk
Study: NCT00670462

Adverse event: cardiac events
Serious: no
Organ System: Cardiac disorders
Frequency: 4 affected / 106 at risk

Adverse event: musculoskeletal events
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 12 affected / 106 at risk

Adverse event: surgical events
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 106 at risk

Adverse event: gastrointestinal events
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 106 at risk

Adverse event: endocrine events
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 106 at risk

Adverse event: pregnancies
Serious: no
Organ System: Pregnancy, puerperium and perinatal conditions
Frequency: 3 affected / 106 at risk

Adverse event: reproductive events
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 106 at risk

Adverse event: Infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 106 at risk

Adverse event: renal event
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 106 at risk

Adverse event: eye events
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 106 at risk

Adverse event: skin event
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 106 at risk

Adverse event: heart attack death
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 107 at risk

Adverse event: cardiac events
Serious: no
Organ System: Cardiac disorders
Frequency: 3 affected / 107 at risk

Adverse event: Skin event
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 107 at risk

Adverse event: musculoskeletal events
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 13 affected / 107 at risk

Adverse event: surgical events
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 107 at risk

Adverse event: ear event
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 107 at risk

Adverse event: gastrointestinal events
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 107 at risk

Adverse event: reproductive events
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 107 at risk

Adverse event: renal event
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 107 at risk

Adverse event: eye events
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 107 at risk
Study: NCT00670540

Adverse event: Death
Serious: yes
Organ System: General disorders
Notes: Validation by an expert committee
Frequency: 822 affected / 4931 at risk

Adverse event: Neoplasm malignant
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Notes: Validation by an expert committee
Frequency: 182 affected / 4931 at risk

Adverse event: cardiovascular
Serious: yes
Organ System: Cardiac disorders
Notes: Validation by an expert committee
Frequency: 310 affected / 4931 at risk

Adverse event: Haemorrhage
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Validation by an expert committee
Frequency: 135 affected / 4931 at risk

Adverse event: Pulmonary Embolism (PE)
Serious: yes
Organ System: Vascular disorders
Notes: Pulmonary Embolism (PE) with Deep Vein Thrombosis (DVT) or not. Validation by an expert committee
Frequency: 122 affected / 4931 at risk

Adverse event: Deep Vein Thrombosis (DVT)
Serious: no
Organ System: Vascular disorders
Notes: Validation by an expert committee
Frequency: 186 affected / 4931 at risk

Adverse event: Superficial Vein Thrombosis (SVT)
Serious: no
Organ System: Vascular disorders
Notes: Validation by an expert committee
Frequency: 81 affected / 4931 at risk

Adverse event: Upper Deep Vein Thrombosis
Serious: no
Organ System: Vascular disorders
Notes: Validation by an expert committee
Frequency: 6 affected / 4931 at risk
Study: NCT00670800

Adverse event: Nausea from Carfentanil at PET
Serious: no
Organ System: General disorders
Frequency: 1 affected / 5 at risk

Adverse event: High Glucose During Oral Glucose Tolerance Test (OGTT)
Serious: no
Organ System: Metabolism and nutrition disorders
Notes: OGTT after 3 ½ months of Metformin. This event was unexpected as Metformin is prescribed to reduce the blood sugar levels and is a widely accepted anti-diabetic drug.
Frequency: 1 affected / 7 at risk
Study: NCT00671060

Adverse event: Other adverse event
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 77 at risk
Study: NCT00671502

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 44 affected / 44 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 23 affected / 278 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 278 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 5 affected / 278 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 8 affected / 278 at risk

Adverse event: Transient ischaemic attack
Serious: yes
Organ System: Cardiac disorders
Notes: occurred after discontinuation of drug therefore not considered treatment emergent
Frequency: 1 affected / 280 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 36 affected / 280 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 12 affected / 280 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 12 affected / 280 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 5 affected / 280 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 4 affected / 280 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 18 affected / 275 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 6 affected / 275 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 6 affected / 275 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 2 affected / 275 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 5 affected / 275 at risk
Study: NCT00671515

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 6 affected / 23 at risk

Adverse event: Dizziness/Lightheadedness
Serious: no
Organ System: General disorders
Frequency: 5 affected / 23 at risk

Adverse event: Increased appetite
Serious: no
Organ System: General disorders
Frequency: 4 affected / 23 at risk

Adverse event: Weight increased
Serious: no
Organ System: General disorders
Frequency: 4 affected / 23 at risk

Adverse event: Ankle/Leg Pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 4 affected / 23 at risk

Adverse event: Vision blurred
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 23 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 23 at risk

Adverse event: Sedation
Serious: no
Organ System: General disorders
Frequency: 2 affected / 23 at risk

Adverse event: Hot flush
Serious: no
Organ System: General disorders
Frequency: 2 affected / 23 at risk

Adverse event: Insomnia
Serious: no
Organ System: General disorders
Frequency: 2 affected / 23 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 23 at risk
Study: NCT00671554

Adverse event: Brain Metastasis
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 2 affected / 3 at risk

Adverse event: Death due to disease progression
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 3 at risk

Adverse event: Post-Operative meningitis
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 3 at risk

Adverse event: Postoperative wound infection
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 3 at risk

Adverse event: injection site reactions
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 3 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 3 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 2 affected / 3 at risk

Adverse event: Injection site reactions
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 3 at risk
Study: NCT00671749

Adverse event: Application site burn
Serious: no
Organ System: General disorders
Frequency: 32 affected / 99 at risk

Adverse event: Application site dryness
Serious: no
Organ System: General disorders
Frequency: 24 affected / 99 at risk

Adverse event: Application site erythema
Serious: no
Organ System: General disorders
Frequency: 10 affected / 99 at risk

Adverse event: Application site exfoliation
Serious: no
Organ System: General disorders
Frequency: 7 affected / 99 at risk

Adverse event: Application site discomfort
Serious: no
Organ System: General disorders
Frequency: 6 affected / 99 at risk
Study: NCT00671853

Adverse event: Dry mouth
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 27 affected / 46 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 46 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 46 at risk

Adverse event: Abdominal discomfort
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 46 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 8 affected / 46 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 7 affected / 46 at risk

Adverse event: Increased appetite
Serious: no
Organ System: General disorders
Frequency: 1 affected / 46 at risk

Adverse event: Sedation
Serious: no
Organ System: Psychiatric disorders
Frequency: 4 affected / 46 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 9 affected / 45 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 45 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 45 at risk

Adverse event: Abdominal discomfort
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 45 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 8 affected / 45 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 3 affected / 45 at risk

Adverse event: Increased appetite
Serious: no
Organ System: General disorders
Frequency: 4 affected / 45 at risk

Adverse event: Sedation
Serious: no
Organ System: Psychiatric disorders
Frequency: 14 affected / 45 at risk
Study: NCT00671918

Adverse event: Myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Notes: Not related to Lymphoseek.
Frequency: 1 affected / 179 at risk

Adverse event: Nausea
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Not related to Lymphoseek.
Frequency: 1 affected / 179 at risk

Adverse event: Vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Not related to Lymphoseek.
Frequency: 1 affected / 179 at risk

Adverse event: Cellulitis
Serious: yes
Organ System: Infections and infestations
Notes: Not related to Lymphoseek.
Frequency: 1 affected / 179 at risk

Adverse event: Modified radical mastectomy
Serious: yes
Organ System: Surgical and medical procedures
Notes: Not related to Lymphoseek.
Frequency: 1 affected / 179 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Notes: Not related to Lymphoseek.
Frequency: 10 affected / 179 at risk
Study: NCT00672555

Adverse event: Complication
Serious: no
Organ System: Infections and infestations
Notes: All complications were assessed. Apart from a bleeding which stopped with compression, all were infections or wound dehiscences.
Frequency: 18 affected / 70 at risk
Study: NCT00672646

Adverse event: Chills
Serious: no
Organ System: General disorders
Frequency: 2 affected / 40 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 40 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 40 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 40 at risk
Study: NCT00672841

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 21 at risk

Adverse event: Liver function test abnormal
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 9 affected / 21 at risk

Adverse event: Hypocalcaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 21 at risk
Study: NCT00672854

Adverse event: Pneumonia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 5 affected / 49 at risk

Adverse event: Urinary tract infection,
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 7 affected / 49 at risk

Adverse event: Bacteraemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 11 affected / 49 at risk

Adverse event: Wound infection,
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 4 affected / 49 at risk

Adverse event: Congestive heart failure,
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 49 at risk

Adverse event: Cardiac arrhythmia,
Serious: yes
Organ System: Cardiac disorders
Frequency: 5 affected / 49 at risk

Adverse event: Vein irritation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 49 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 7 affected / 51 at risk

Adverse event: Urinary tract infection,
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 7 affected / 51 at risk

Adverse event: Bacteraemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 11 affected / 51 at risk

Adverse event: Wound infection,
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 11 affected / 51 at risk

Adverse event: Acute myocardial infarction,
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 51 at risk

Adverse event: Congestive heart failure,
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 51 at risk

Adverse event: Cardiac arrhythmia,
Serious: yes
Organ System: Cardiac disorders
Frequency: 6 affected / 51 at risk

Adverse event: Vein irritation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 51 at risk
Study: NCT00673114

Adverse event: Encephalitis
Serious: yes
Organ System: Infections and infestations
Notes: Not study related and not unexpected per the PI.
Frequency: 1 affected / 3 at risk

Adverse event: Chronic GVHD
Serious: yes
Organ System: General disorders
Notes: Not directly related to the study and not unexpected per the PI.
Frequency: 1 affected / 3 at risk

Adverse event: Relapse
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Not study related and not unexpected per the PI.
Frequency: 1 affected / 3 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Not directly related to the study and not unexpected per the PI.
Frequency: 1 affected / 3 at risk

Adverse event: Respiratory failure
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Not directly related to the study and not unexpected per the PI.
Frequency: 1 affected / 3 at risk

Adverse event: Multi-system organ failure
Serious: yes
Organ System: General disorders
Notes: Not directly related to the study and not unexpected per the PI.
Frequency: 1 affected / 3 at risk

Adverse event: Sepsis
Serious: yes
Organ System: Infections and infestations
Notes: Not directly related to the study and not unexpected per the PI.
Frequency: 1 affected / 3 at risk
Study: NCT00673179

Adverse event: Rash
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Notes: Grade 4
Frequency: 1 affected / 7 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Grade 2
Frequency: 1 affected / 7 at risk
Study: NCT00673400

Adverse event: persisting pain due to residual staples
Serious: no
Organ System: Injury, poisoning and procedural complications
Notes: Dindo grade IIIa: intervention without general anesthesia
Frequency: 2 affected / 52 at risk

Adverse event: Thrombosis
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: perianal venous thrombosis 5 weeks postoperatively Dindo grade IIIb: incision under general anesthesia
Frequency: 1 affected / 52 at risk

Adverse event: Urinary retention
Serious: no
Organ System: Renal and urinary disorders
Notes: Dindo grade IIIa: intervention without general anesthesia
Frequency: 1 affected / 52 at risk
Study: NCT00673660

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 1 affected / 153 at risk

Adverse event: Back pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 153 at risk

Adverse event: Hypersensitivity
Serious: no
Organ System: General disorders
Frequency: 1 affected / 153 at risk

Adverse event: Arthralgia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 153 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 1 affected / 153 at risk

Adverse event: Nausea
Serious: no
Organ System: General disorders
Frequency: 2 affected / 153 at risk

Adverse event: Flatulence
Serious: no
Organ System: General disorders
Frequency: 2 affected / 153 at risk

Adverse event: Hepatic enzyme increased
Serious: no
Organ System: General disorders
Frequency: 1 affected / 153 at risk

Adverse event: Other
Serious: no
Organ System: General disorders
Frequency: 3 affected / 153 at risk

Adverse event: Back pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 76 at risk

Adverse event: Hypersensitivity
Serious: no
Organ System: General disorders
Frequency: 1 affected / 76 at risk

Adverse event: Arthralgia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 76 at risk

Adverse event: Hepatic enzyme increased
Serious: no
Organ System: General disorders
Frequency: 2 affected / 76 at risk

Adverse event: Rash on hands
Serious: no
Organ System: General disorders
Frequency: 1 affected / 76 at risk

Adverse event: Back pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 44 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 44 at risk

Adverse event: Pharyngitis
Serious: no
Organ System: General disorders
Frequency: 1 affected / 44 at risk

Adverse event: Hepatic enzyme increased
Serious: no
Organ System: General disorders
Frequency: 1 affected / 44 at risk

Adverse event: Cough
Serious: no
Organ System: General disorders
Frequency: 1 affected / 44 at risk

Adverse event: Abdominal discomfort
Serious: no
Organ System: General disorders
Frequency: 1 affected / 44 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 1 affected / 268 at risk

Adverse event: Myalgia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 268 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 1 affected / 268 at risk

Adverse event: Constipation
Serious: no
Organ System: General disorders
Frequency: 1 affected / 268 at risk

Adverse event: Hepatic enzyme increased
Serious: no
Organ System: General disorders
Frequency: 1 affected / 268 at risk

Adverse event: Visual impairment
Serious: no
Organ System: General disorders
Frequency: 1 affected / 268 at risk

Adverse event: Renal failure
Serious: no
Organ System: General disorders
Frequency: 1 affected / 268 at risk

Adverse event: Vertigo
Serious: no
Organ System: General disorders
Frequency: 1 affected / 268 at risk