Study: NCT00384033

Adverse event: Injury
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 161 at risk

Adverse event: Asthma
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 161 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: General disorders
Frequency: 12 affected / 161 at risk

Adverse event: Asthenia
Serious: no
Organ System: General disorders
Frequency: 9 affected / 161 at risk

Adverse event: Back pain
Serious: no
Organ System: General disorders
Frequency: 10 affected / 161 at risk

Adverse event: Influenza
Serious: no
Organ System: General disorders
Frequency: 8 affected / 161 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 38 affected / 161 at risk

Adverse event: Infection
Serious: no
Organ System: General disorders
Frequency: 7 affected / 161 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Frequency: 9 affected / 161 at risk

Adverse event: Withdrawal syndrome
Serious: no
Organ System: General disorders
Frequency: 24 affected / 161 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 161 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 161 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 22 affected / 161 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 25 affected / 161 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 9 affected / 161 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 22 affected / 161 at risk

Adverse event: Vomitting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 161 at risk

Adverse event: Myalgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 9 affected / 161 at risk

Adverse event: Abnormal dreams
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 161 at risk

Adverse event: Anxiety
Serious: no
Organ System: Nervous system disorders
Frequency: 11 affected / 161 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 15 affected / 161 at risk

Adverse event: Insomnia
Serious: no
Organ System: Nervous system disorders
Frequency: 9 affected / 161 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 12 affected / 161 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 20 affected / 161 at risk

Adverse event: Hyperhidrosis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 4 affected / 161 at risk

Adverse event: Visual impairment
Serious: no
Organ System: General disorders
Frequency: 2 affected / 161 at risk

Adverse event: Injury
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 148 at risk

Adverse event: Suicidal ideation
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 148 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: General disorders
Frequency: 8 affected / 148 at risk

Adverse event: Asthenia
Serious: no
Organ System: General disorders
Frequency: 15 affected / 148 at risk

Adverse event: Back pain
Serious: no
Organ System: General disorders
Frequency: 3 affected / 148 at risk

Adverse event: Influenza
Serious: no
Organ System: General disorders
Frequency: 7 affected / 148 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 27 affected / 148 at risk

Adverse event: Infection
Serious: no
Organ System: General disorders
Frequency: 10 affected / 148 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Frequency: 3 affected / 148 at risk

Adverse event: Withdrawal syndrome
Serious: no
Organ System: General disorders
Frequency: 42 affected / 148 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 14 affected / 148 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 9 affected / 148 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 18 affected / 148 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 26 affected / 148 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 8 affected / 148 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 36 affected / 148 at risk

Adverse event: Vomitting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 148 at risk

Adverse event: Myalgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 6 affected / 148 at risk

Adverse event: Abnormal dreams
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 148 at risk

Adverse event: Anxiety
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 148 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 15 affected / 148 at risk

Adverse event: Insomnia
Serious: no
Organ System: Nervous system disorders
Frequency: 23 affected / 148 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 16 affected / 148 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 24 affected / 148 at risk

Adverse event: Hyperhidrosis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 9 affected / 148 at risk

Adverse event: Visual impairment
Serious: no
Organ System: General disorders
Frequency: 8 affected / 148 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 150 at risk

Adverse event: Heavy menstrual bleeding
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 150 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: General disorders
Frequency: 8 affected / 150 at risk

Adverse event: Asthenia
Serious: no
Organ System: General disorders
Frequency: 19 affected / 150 at risk

Adverse event: Influenza
Serious: no
Organ System: General disorders
Frequency: 12 affected / 150 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 28 affected / 150 at risk

Adverse event: Infection
Serious: no
Organ System: General disorders
Frequency: 15 affected / 150 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Frequency: 4 affected / 150 at risk

Adverse event: Withdrawal syndrome
Serious: no
Organ System: General disorders
Frequency: 42 affected / 150 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 14 affected / 150 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 10 affected / 150 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 24 affected / 150 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 31 affected / 150 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 10 affected / 150 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 40 affected / 150 at risk

Adverse event: Vomitting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 11 affected / 150 at risk

Adverse event: Myalgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 6 affected / 150 at risk

Adverse event: Abnormal dreams
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 150 at risk

Adverse event: Anxiety
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 150 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 26 affected / 150 at risk

Adverse event: Insomnia
Serious: no
Organ System: Nervous system disorders
Frequency: 28 affected / 150 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 18 affected / 150 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 20 affected / 150 at risk

Adverse event: Hyperhidrosis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 9 affected / 150 at risk

Adverse event: Visual impairment
Serious: no
Organ System: General disorders
Frequency: 9 affected / 150 at risk

Adverse event: Suicide attempt
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 157 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: General disorders
Frequency: 15 affected / 157 at risk

Adverse event: Asthenia
Serious: no
Organ System: General disorders
Frequency: 21 affected / 157 at risk

Adverse event: Back pain
Serious: no
Organ System: General disorders
Frequency: 5 affected / 157 at risk

Adverse event: Influenza
Serious: no
Organ System: General disorders
Frequency: 5 affected / 157 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 30 affected / 157 at risk

Adverse event: Infection
Serious: no
Organ System: General disorders
Frequency: 6 affected / 157 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Frequency: 4 affected / 157 at risk

Adverse event: Withdrawal syndrome
Serious: no
Organ System: General disorders
Frequency: 49 affected / 157 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 29 affected / 157 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 17 affected / 157 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 26 affected / 157 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 33 affected / 157 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 157 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 52 affected / 157 at risk

Adverse event: Vomitting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 14 affected / 157 at risk

Adverse event: Myalgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 5 affected / 157 at risk

Adverse event: Abnormal dreams
Serious: no
Organ System: Nervous system disorders
Frequency: 12 affected / 157 at risk

Adverse event: Anxiety
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 157 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 27 affected / 157 at risk

Adverse event: Insomnia
Serious: no
Organ System: Nervous system disorders
Frequency: 37 affected / 157 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 33 affected / 157 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 25 affected / 157 at risk

Adverse event: Hyperhidrosis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 19 affected / 157 at risk

Adverse event: Visual impairment
Serious: no
Organ System: General disorders
Frequency: 4 affected / 157 at risk