TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT02844582

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 2 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 2 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 2 affected / 2 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 2 at risk

Adverse event: Hot flush
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 2 at risk

Adverse event: Neutrophil count decreased
Serious: no
Organ System: Investigations
Frequency: 2 affected / 2 at risk

Adverse event: Non-cardiac chest pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 2 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 2 at risk

Adverse event: Renal and urinary disorders - Other, specify
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 2 at risk

Adverse event: White blood cell count decreased
Serious: no
Organ System: Investigations
Frequency: 2 affected / 2 at risk
Study: NCT02844777

Adverse event: Bronchitis
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 29 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 29 at risk

Adverse event: benign sero-mucinous cystadenoma of abdomen
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 32 at risk

Adverse event: Bronchitis
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 32 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 32 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 32 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 32 at risk
Study: NCT02844907

Adverse event: Bruising at IV site
Serious: no
Organ System: General disorders
Frequency: 3 affected / 6 at risk

Adverse event: Transient Nausea
Serious: no
Organ System: General disorders
Frequency: 1 affected / 6 at risk

Adverse event: Transient Nausea
Serious: no
Organ System: General disorders
Frequency: 1 affected / 6 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 2 affected / 6 at risk

Adverse event: Blood glucose levels between 70 and 80 mg/dl that were asymptomatic
Serious: no
Organ System: General disorders
Frequency: 2 affected / 6 at risk
Study: NCT02844920

Adverse event: Gall Stones
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 37 at risk
Study: NCT02844933

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 4 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 4 at risk

Adverse event: Abdominal cramping
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 4 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 4 at risk

Adverse event: Impetigo
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 4 at risk

Adverse event: Cellulitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 4 at risk

Adverse event: Ear infection
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 4 at risk

Adverse event: Bacterial infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 4 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 3 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 3 at risk

Adverse event: Seizure
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 3 at risk
Study: NCT02845297

Adverse event: Sepsis
Serious: yes
Organ System: Infections and infestations
Frequency: 4 affected / 40 at risk

Adverse event: Pneumonia
Serious: no
Organ System: Infections and infestations
Frequency: 6 affected / 40 at risk

Adverse event: Sepsis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 27 at risk
Study: NCT02845440

Adverse event: Medical hospitalization
Serious: yes
Organ System: General disorders
Frequency: 43 affected / 333 at risk

Adverse event: Psychiatric hospitalization
Serious: yes
Organ System: Psychiatric disorders
Frequency: 66 affected / 333 at risk

Adverse event: Imprisonment
Serious: no
Organ System: Social circumstances
Frequency: 13 affected / 333 at risk

Adverse event: Medical hospitalization
Serious: yes
Organ System: General disorders
Frequency: 59 affected / 336 at risk

Adverse event: Psychiatric hospitalization
Serious: yes
Organ System: Psychiatric disorders
Frequency: 82 affected / 336 at risk

Adverse event: Imprisonment
Serious: no
Organ System: Social circumstances
Frequency: 8 affected / 336 at risk

Adverse event: Medical hospitalization
Serious: yes
Organ System: General disorders
Frequency: 47 affected / 341 at risk

Adverse event: Psychiatric hospitalization
Serious: yes
Organ System: Psychiatric disorders
Frequency: 75 affected / 341 at risk

Adverse event: Imprisonment
Serious: no
Organ System: Social circumstances
Frequency: 7 affected / 341 at risk

Adverse event: Medical hospitalization
Serious: yes
Organ System: General disorders
Frequency: 10 affected / 78 at risk

Adverse event: Psychiatric hospitalization
Serious: yes
Organ System: Psychiatric disorders
Frequency: 19 affected / 78 at risk

Adverse event: Imprisonment
Serious: no
Organ System: Social circumstances
Frequency: 2 affected / 78 at risk

Adverse event: Medical hospitalization
Serious: yes
Organ System: General disorders
Frequency: 10 affected / 77 at risk

Adverse event: Psychiatric hospitalization
Serious: yes
Organ System: Psychiatric disorders
Frequency: 16 affected / 77 at risk

Adverse event: Imprisonment
Serious: no
Organ System: Social circumstances
Frequency: 1 affected / 77 at risk
Study: NCT02846233

Adverse event: Mild hypoglycemia
Serious: no
Organ System: Metabolism and nutrition disorders
Notes: Mild hypoglycemia event (BG 40-69 mg/dL)
Frequency: 1 affected / 12 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 9 affected / 12 at risk

Adverse event: Mild hypoglycemia
Serious: no
Organ System: Metabolism and nutrition disorders
Notes: Mild hypoglycemia event (BG 40-69 mg/dL)
Frequency: 2 affected / 10 at risk

Adverse event: Hypoglycaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Notes: Severe hypoglycemia event (BG \<40 mg/dL)
Frequency: 1 affected / 10 at risk
Study: NCT02846558

Adverse event: Migraine
Serious: no
Organ System: Nervous system disorders
Notes: One patient with a known history of migraine headaches experienced migraines on fasting days for the intermittent calorie restriction option, and self-discontinued the dietary intervention.
Frequency: 1 affected / 10 at risk
Study: NCT02846792

Adverse event: Atrioventricular block
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 5 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 5 at risk

Adverse event: Musculoskeletal and connective tissue disorder - Other
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Prophylactic surgical stabilization of the left femoral head and left proximal tibia due to bone metastases
Frequency: 1 affected / 5 at risk

Adverse event: Respiratory, thoracic and mediastinal disorders - Other
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Progressive disease
Frequency: 1 affected / 5 at risk

Adverse event: Infusion related reaction
Serious: no
Organ System: General disorders
Frequency: 2 affected / 5 at risk

Adverse event: Stomatitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 5 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 5 at risk

Adverse event: Pneumonia
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 5 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 5 at risk

Adverse event: Musculoskeletal and connective tissue disorder - Other
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Radiation therapy to painful bone metastases
Frequency: 1 affected / 5 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 5 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 5 at risk
Study: NCT02847494

Adverse event: Akathisia
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 109 at risk

Adverse event: Injection site reaction
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 109 at risk

Adverse event: Akathisia
Serious: no
Organ System: Nervous system disorders
Frequency: 7 affected / 111 at risk

Adverse event: Injection site reaction
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 9 affected / 111 at risk
Study: NCT02848092

Adverse event: Simulator sickness during training
Serious: no
Organ System: Nervous system disorders
Frequency: 6 affected / 76 at risk

Adverse event: Frustration during training
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 76 at risk

Adverse event: Simulator sickness during assessment
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 76 at risk

Adverse event: Simulator sickness during training
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 76 at risk
Study: NCT02848599

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 35 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 35 at risk

Adverse event: Paraesthesia
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 35 at risk
Study: NCT02848664

Adverse event: Increase in temperature for more than 3 days
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Increase in body temperature necessitating visit to primary care physician for prophylactic antibiotic intervention to prevent aspiration pneumonia
Frequency: 3 affected / 7 at risk
Study: NCT02848781

Adverse event: Procedure Complication
Serious: yes
Organ System: Cardiac disorders
Frequency: 5 affected / 60 at risk

Adverse event: Rehospitalization
Serious: yes
Organ System: Cardiac disorders
Frequency: 17 affected / 60 at risk

Adverse event: Mortality
Serious: yes
Organ System: Cardiac disorders
Frequency: 5 affected / 60 at risk

Adverse event: Arrhythmia, Palpitation
Serious: no
Organ System: Cardiac disorders
Frequency: 19 affected / 60 at risk

Adverse event: Rehospitalization
Serious: yes
Organ System: Cardiac disorders
Frequency: 20 affected / 61 at risk

Adverse event: Mortality
Serious: yes
Organ System: Cardiac disorders
Frequency: 4 affected / 61 at risk

Adverse event: Arrhythmia, Palpitation
Serious: no
Organ System: Cardiac disorders
Frequency: 31 affected / 61 at risk

Adverse event: Procedure Complication
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 47 at risk

Adverse event: Rehospitalization
Serious: yes
Organ System: Cardiac disorders
Frequency: 12 affected / 47 at risk

Adverse event: Mortality
Serious: yes
Organ System: Cardiac disorders
Frequency: 3 affected / 47 at risk

Adverse event: Arrhythmia, Palpitation
Serious: no
Organ System: Cardiac disorders
Frequency: 15 affected / 47 at risk
Study: NCT02849171

Adverse event: Hyperglycaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 6 affected / 8 at risk

Adverse event: Lymphocyte count decreased
Serious: no
Organ System: Investigations
Frequency: 5 affected / 8 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 4 affected / 8 at risk

Adverse event: Hypoalbuminaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 8 at risk

Adverse event: Platelet count decreased
Serious: no
Organ System: Investigations
Frequency: 4 affected / 8 at risk

Adverse event: White blood cell count decreased
Serious: no
Organ System: Investigations
Frequency: 4 affected / 8 at risk

Adverse event: Hypokalaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 8 at risk

Adverse event: Hyponatraemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 8 at risk

Adverse event: Hypocalcaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 8 at risk

Adverse event: Neutrophil count decreased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 8 at risk
Study: NCT02849509

Adverse event: Diverticulum intestinal haemorrhagic
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 379 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 379 at risk

Adverse event: Lower gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 379 at risk

Adverse event: Upper gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 379 at risk

Adverse event: Multiple organ dysfunction syndrome
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 379 at risk

Adverse event: Metabolic acidosis
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 379 at risk

Adverse event: Cerebrovascular accident
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 379 at risk

Adverse event: Hypovolaemic shock
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 379 at risk

Adverse event: Melaena
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 591 at risk

Adverse event: International normalised ratio increased
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 343 at risk

Adverse event: Acute myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 343 at risk

Adverse event: Overdose
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 343 at risk

Adverse event: Cerebral infarction
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 343 at risk

Adverse event: Haematuria
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 343 at risk
Study: NCT02849548

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 4 affected / 13 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 13 at risk

Adverse event: Depression
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 13 at risk

Adverse event: Anxiety
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 13 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 13 at risk

Adverse event: Nightmare
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 13 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 3 affected / 14 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 14 at risk

Adverse event: Depression
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 14 at risk

Adverse event: Anxiety
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 14 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 14 at risk
Study: NCT02849587

Adverse event: Discomfort in arm
Serious: no
Organ System: Injury, poisoning and procedural complications
Notes: Venous catheter was used to collect blood
Frequency: 1 affected / 65 at risk

Adverse event: Numbness in arm
Serious: no
Organ System: Injury, poisoning and procedural complications
Notes: Venous catheter was used to collect blood
Frequency: 1 affected / 65 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 70 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 70 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 70 at risk

Adverse event: Sweats
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 70 at risk

Adverse event: Blood pressure decreased
Serious: no
Organ System: Vascular disorders
Frequency: 3 affected / 70 at risk

Adverse event: Blood pressure increased
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 70 at risk

Adverse event: Heart rate abnormal
Serious: no
Organ System: Cardiac disorders
Frequency: 12 affected / 70 at risk

Adverse event: Neck pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 70 at risk

Adverse event: Syncope
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 70 at risk

Adverse event: Discomfort in arm
Serious: no
Organ System: Injury, poisoning and procedural complications
Notes: Venous catheter was used to collect blood
Frequency: 1 affected / 70 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 70 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 64 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 64 at risk

Adverse event: Blood pressure decreased
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 64 at risk

Adverse event: Heart rate abnormal
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 64 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 64 at risk

Adverse event: Peripheral swelling
Serious: no
Organ System: Injury, poisoning and procedural complications
Notes: Venous catheter was used to collect blood
Frequency: 1 affected / 64 at risk
Study: NCT02849678

Adverse event: Surgical Complications
Serious: no
Organ System: Surgical and medical procedures
Notes: Five patients reported surgical complications including dehydration with acute renal failure, small bowel obstruction, rectal bleeding, and anastomotic dehiscence with pelvic abscess. Further separation of is not possible.
Frequency: 1 affected / 17 at risk

Adverse event: Surgical Complications
Serious: no
Organ System: Surgical and medical procedures
Notes: Five patients reported surgical complications including dehydration with acute renal failure, small bowel obstruction, rectal bleeding, and anastomotic dehiscence with pelvic abscess. Further separation of is not possible.
Frequency: 4 affected / 18 at risk
Study: NCT02849704

Adverse event: Abdominal Pain/Discomfort
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 24 at risk

Adverse event: Abdominal Pain/Discomfort
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 24 at risk
Study: NCT02849990

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 16 affected / 22 at risk

Adverse event: Mood altered
Serious: no
Organ System: General disorders
Frequency: 5 affected / 22 at risk

Adverse event: Insomnia
Serious: no
Organ System: General disorders
Frequency: 3 affected / 22 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 2 affected / 22 at risk

Adverse event: Musculoskeletal disorder
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 6 affected / 22 at risk

Adverse event: Cognitive Changes
Serious: no
Organ System: Nervous system disorders
Frequency: 11 affected / 22 at risk

Adverse event: Headaches
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 22 at risk

Adverse event: Balance Problem
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 22 at risk

Adverse event: Hot flush
Serious: no
Organ System: Endocrine disorders
Frequency: 18 affected / 22 at risk

Adverse event: Gastrointestinal disorder
Serious: no
Organ System: General disorders
Frequency: 11 affected / 22 at risk

Adverse event: Hypertransaminasaemia
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 4 affected / 22 at risk

Adverse event: Injection site reaction
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 22 at risk

Adverse event: Epistaxis
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 22 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 9 affected / 22 at risk

Adverse event: Hypotension
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 22 at risk
Study: NCT02850068

Adverse event: small access site hematoma
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Small hematoma at site of access for procedure
Frequency: 1 affected / 20 at risk

Adverse event: skin discoloration without ulcer that resolved by 3-months follow-up evaluation without intervention
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 13 affected / 20 at risk

Adverse event: great toe plantar numbness that resolved within 2 weeks
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 20 at risk
Study: NCT02850276

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 15 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 15 at risk

Adverse event: Flatulence
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 15 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 1 affected / 15 at risk
Study: NCT02850601

Adverse event: constipation; abdomional discomfort
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Stopped study meds and recovered after 1 day
Frequency: 1 affected / 12 at risk