Study: NCT01198327

Adverse event: Death resulting from pre-existing idiopathic pulmonary fibrosis
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 66 at risk

Adverse event: Death of unknown cause
Serious: yes
Organ System: General disorders
Notes: Reason for death could not be found out, despite multiple attempts to contact family members.
Frequency: 1 affected / 66 at risk

Adverse event: ECG for elective knee surgery showed inverted T waves, patient asymptomatic, admitted for workup
Serious: yes
Organ System: Cardiac disorders
Notes: Coronary artery bypass surgery, recovered
Frequency: 1 affected / 66 at risk

Adverse event: Mild chest discomfort for 6 mos, coronary angiography showed 2 obstructions
Serious: yes
Organ System: Cardiac disorders
Notes: Elective placement of 2 stents without complications, recovered
Frequency: 1 affected / 66 at risk

Adverse event: Tachycardia and went to the emergency department
Serious: yes
Organ System: Cardiac disorders
Notes: Cardioverter defibrillator implanted, recovered
Frequency: 1 affected / 66 at risk

Adverse event: Syncope with fall because of arrhythmia
Serious: yes
Organ System: Cardiac disorders
Notes: Pacemaker implanted, recovered
Frequency: 1 affected / 66 at risk

Adverse event: Chronic atrial fibrillation, CVA; bladder cancer identified during hospitalization
Serious: yes
Organ System: General disorders
Notes: Pacemaker implanted, administered anticoagulants,underwent surgery for bladder cancer; recovered
Frequency: 1 affected / 66 at risk

Adverse event: Head injury resulting from fall
Serious: yes
Organ System: General disorders
Notes: Received staples for scalp laceration, recovered
Frequency: 1 affected / 66 at risk

Adverse event: Urinary tract infection leading to septic shock
Serious: yes
Organ System: Infections and infestations
Notes: Hospitalized, recovered
Frequency: 1 affected / 66 at risk

Adverse event: Hospitalized for pneumonia
Serious: yes
Organ System: Infections and infestations
Notes: Recovered
Frequency: 2 affected / 66 at risk

Adverse event: Hospitalized for elective surgery
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Recovered
Frequency: 2 affected / 66 at risk

Adverse event: Vitreous hemorrhage,
Serious: yes
Organ System: Eye disorders
Notes: resolved spontaneously
Frequency: 1 affected / 66 at risk

Adverse event: Second branch retinal vein occlusion in same eye
Serious: yes
Organ System: Eye disorders
Notes: Patient with an inferior branch retinal vein occlusion had resolution of edema, but a superior branch vein occlusion developed 27 months after last ranibizumab injection. Had severe ischemia, and neovascular glaucoma developed.
Frequency: 1 affected / 66 at risk

Adverse event: Retinal tear in a patient with branch retinal vein occlusion who did not receive any treatment
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 66 at risk

Adverse event: Severe reaction to povidon-iodine
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 66 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: General disorders
Notes: This adverse event was specified as "Upper respiratory Infection". It was reported if a study subject had a common cold, viral bronchitis or sinusitis.
Frequency: 20 affected / 66 at risk

Adverse event: Ocular discomfort
Serious: no
Organ System: Eye disorders
Notes: Discomfort after intravitreal injection
Frequency: 13 affected / 66 at risk

Adverse event: Subconjuctival Hemorrhage
Serious: no
Organ System: Eye disorders
Frequency: 13 affected / 66 at risk

Adverse event: Vitreous Hemmorhage
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 66 at risk