TrialPanorama/TrialPanorama-database huggingface dataset:
Study: 10490723

Adverse event: platelet count

Adverse event: platelet count

Adverse event: antithrombin iii

Adverse event: transplant

Adverse event: antithrombin iii

Adverse event: transplant
Study: 30414822

Adverse event: mass

Adverse event: mass
Study: 28720139

Adverse event: arthritis

Adverse event: disease activity score
Study: 26829760

Adverse event: pain
Study: 24355210

Adverse event: hypoxia
Study: 21371166

Adverse event: hypoxia

Adverse event: sedation
Study: 19098058

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction
Study: 21371166

Adverse event: heart rate

Adverse event: hypoxia

Adverse event: sedation
Study: 17874530

Adverse event: blood glucose
Study: 14687174

Adverse event: discomfort

Adverse event: irritable bowel syndrome
Study: 14687174

Adverse event: discomfort

Adverse event: irritable bowel syndrome

Adverse event: discomfort

Adverse event: irritable bowel syndrome
Study: 11758266

Adverse event: pain
Study: 26829760

Adverse event: swelling
Study: 9223108

Adverse event: apoptosis
Study: 9223108

Adverse event: elderly

Adverse event: apoptosis

Adverse event: apoptosis

Adverse event: elderly

Adverse event: apoptosis
Study: 7967758

Adverse event: kyphosis
Study: 9223108

Adverse event: apoptosis

Adverse event: apoptosis
Study: 30530584

Adverse event: live birth

Adverse event: ovarian hyperstimulation syndrome

Adverse event: live birth
Study: 17661864

Adverse event: sedation

Adverse event: pain
Study: 31711244

Adverse event: aspiration

Adverse event: surgery
Study: 11823394

Adverse event: pain
Study: 16174858

Adverse event: mammogram
Study: 23592677

Adverse event: depression
Study: 6113234

Adverse event: depression

Adverse event: anxiety

Adverse event: depression

Adverse event: anxiety

Adverse event: depression

Adverse event: anxiety

Adverse event: depression

Adverse event: anxiety
Study: 9223108

Adverse event: elderly

Adverse event: apoptosis
Study: 25489056

Adverse event: blood pressure increased

Adverse event: heart rate
Study: 28640161

Adverse event: dyspareunia
Study: 19679575

Adverse event: pain

Adverse event: disability
Study: 19853886

Adverse event: blood lead

Adverse event: blood lead

Adverse event: blood lead

Adverse event: blood lead
Study: 6113234

Adverse event: depression

Adverse event: anxiety
Study: 2210893

Adverse event: inflammation

Adverse event: dilated cardiomyopathy

Adverse event: cardiomyopathy
Study: 17376293

Adverse event: high density lipoprotein

Adverse event: low density lipoprotein

Adverse event: fasting

Adverse event: fasting
Study: 15199325

Adverse event: viral load
Study: 11772696

Adverse event: eating disorder

Adverse event: binge eating

Adverse event: vomiting
Study: 9640894

Adverse event: injury
Study: 2673590

Adverse event: leprosy
Study: 1190686

Adverse event: fat embolism

Adverse event: fat embolism syndrome

Adverse event: embolism

Adverse event: fat embolism

Adverse event: fat embolism syndrome

Adverse event: embolism
Study: 22334056

Adverse event: irritability

Adverse event: mood swings

Adverse event: night sweats

Adverse event: menopausal symptoms
Study: 16156456

Adverse event: transfusion

Adverse event: transfusion

Adverse event: drainage

Adverse event: drainage
Study: 12610040

Adverse event: blood glucose

Adverse event: fasting

Adverse event: blood glucose

Adverse event: fasting
Study: 10369072

Adverse event: apoptosis

Adverse event: chemotherapy
Study: 7032533

Adverse event: blood triglycerides

Adverse event: blood cholesterol
Study: 31932201

Adverse event: vitamin d

Adverse event: vitamin d
Study: 29251686

Adverse event: blood glucose

Adverse event: fasting

Adverse event: insulin resistance

Adverse event: oxygen consumption

Adverse event: oxygen consumption

Adverse event: waist circumference

Adverse event: waist circumference
Study: 26988095

Adverse event: spirometry
Study: 22454251

Adverse event: adverse event

Adverse event: adverse event
Study: 20446847

Adverse event: death

Adverse event: illness

Adverse event: death

Adverse event: illness

Adverse event: death

Adverse event: illness

Adverse event: death

Adverse event: illness

Adverse event: death
Study: 18021264

Adverse event: discomfort
Study: 15460663

Adverse event: blood glucose

Adverse event: blood glucose
Study: 29102524

Adverse event: colonoscopy

Adverse event: colonoscopy

Adverse event: colonoscopy

Adverse event: colonoscopy
Study: 24944054

Adverse event: weight

Adverse event: body mass index

Adverse event: mass
Study: 23611825

Adverse event: vitamin d

Adverse event: vitamin d
Study: 19926166

Adverse event: sepsis

Adverse event: sepsis
Study: 16616748

Adverse event: pregnancy

Adverse event: pregnancy
Study: 8621005

Adverse event: fasting

Adverse event: fasting

Adverse event: fasting
Study: 1582188

Adverse event: exercise test

Adverse event: heart rate

Adverse event: exercise test

Adverse event: heart rate
Study: 9867054

Adverse event: spinal cord injury

Adverse event: injury
Study: 21300083

Adverse event: weight

Adverse event: waist circumference

Adverse event: heart rate
Study: 12101864

Adverse event: abortion

Adverse event: abortion

Adverse event: abortion
Study: 2536867

Adverse event: chemotherapy
Study: 4465285

Adverse event: cystinuria
Study: 28839341

Adverse event: schizophrenia

Adverse event: schizophrenia
Study: 11903412

Adverse event: weight

Adverse event: weight increased

Adverse event: mass

Adverse event: mass
Study: 23406684

Adverse event: left ventricular hypertrophy

Adverse event: ventricular hypertrophy

Adverse event: hypertrophy
Study: 9388412

Adverse event: goitre

Adverse event: iodine deficiency

Adverse event: iodine deficiency
Study: 7532743

Adverse event: microalbuminuria

Adverse event: microalbuminuria

Adverse event: amylase

Adverse event: amylase

Adverse event: alpha 1 microglobulin

Adverse event: microalbuminuria
Study: 28597253

Adverse event: pain

Adverse event: fatigue

Adverse event: vomiting

Adverse event: nausea

Adverse event: rash
Study: 15699266

Adverse event: necrosis
Study: 8553353

Adverse event: infant
Study: 28185468

Adverse event: pancreatitis

Adverse event: pancreatitis
Study: 11350571

Adverse event: death
Study: 23123345

Adverse event: filariasis
Study: 21785478

Adverse event: injection

Adverse event: injection

Adverse event: pain

Adverse event: pain
Study: 19514296

Adverse event: depression

Adverse event: asthenia
Study: 16691061

Adverse event: intermenstrual bleeding

Adverse event: pelvic pain

Adverse event: pain
Study: 11350571

Adverse event: death

Adverse event: death

Adverse event: death
Study: 8498421

Adverse event: pain

Adverse event: pain

Adverse event: manganese increased

Adverse event: pain

Adverse event: manganese

Adverse event: manganese increased

Adverse event: pain

Adverse event: manganese
Study: 31885292

Adverse event: discharge
Study: 31913413

Adverse event: mastectomy
Study: 18637924

Adverse event: infection

Adverse event: wound

Adverse event: wound infection

Adverse event: infection

Adverse event: wound

Adverse event: wound infection

Adverse event: wound

Adverse event: wound

Adverse event: visual analogue scale

Adverse event: pain
Study: 12892319

Adverse event: coronary artery occlusion

Adverse event: ventricular fibrillation

Adverse event: coronary artery occlusion

Adverse event: ventricular fibrillation

Adverse event: coronary artery occlusion

Adverse event: ventricular fibrillation

Adverse event: coronary artery occlusion

Adverse event: ventricular fibrillation
Study: 11156724

Adverse event: transfusion
Study: 30990088

Adverse event: depression

Adverse event: married
Study: 27197965

Adverse event: prostate cancer
Study: 23759461

Adverse event: weight

Adverse event: weight decreased

Adverse event: body mass index

Adverse event: mass

Adverse event: fasting

Adverse event: high density lipoprotein

Adverse event: weight
Study: 16804925

Adverse event: chemotherapy
Study: 10100069

Adverse event: weight
Study: 6814281

Adverse event: asthma
Study: 17308899

Adverse event: pain

Adverse event: pain
Study: 14973308

Adverse event: dizziness

Adverse event: tachycardia

Adverse event: nausea
Study: 7946592

Adverse event: vomiting

Adverse event: nausea

Adverse event: oedema

Adverse event: face oedema

Adverse event: weight
Study: 26303634

Adverse event: transplant

Adverse event: transplant

Adverse event: transplant

Adverse event: weight
Study: 21633921

Adverse event: ejection fraction

Adverse event: mass
Study: 12388895

Adverse event: pain
Study: 31223101

Adverse event: infection

Adverse event: infection

Adverse event: infection
Study: 22261136

Adverse event: pain

Adverse event: pain
Study: 20498245

Adverse event: biopsy
Study: 17645881

Adverse event: injury

Adverse event: infusion

Adverse event: vitamin c

Adverse event: vitamin c

Adverse event: vitamin c
Study: 15935015

Adverse event: fall

Adverse event: fall
Study: 12623727

Adverse event: fear

Adverse event: fear

Adverse event: fear
Study: 9819296

Adverse event: asthma

Adverse event: asthma
Study: 799569

Adverse event: headache

Adverse event: syncope
Study: 28607888

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: surgery

Adverse event: haemorrhage
Study: 26048144

Adverse event: antiretroviral therapy
Study: 23932774

Adverse event: fatigue

Adverse event: balance test

Adverse event: fatigue

Adverse event: interactions

Adverse event: fatigue

Adverse event: interactions
Study: 18312044

Adverse event: illness

Adverse event: depression

Adverse event: substance abuse
Study: 16176847

Adverse event: injection

Adverse event: induration
Study: 11324210

Adverse event: bone loss
Study: 3076661

Adverse event: chest pain

Adverse event: pain

Adverse event: fall
Study: 1467049

Adverse event: ischaemia

Adverse event: depression
Study: 31490292

Adverse event: pain

Adverse event: pain

Adverse event: paresis

Adverse event: paresis

Adverse event: spirometry
Study: 25182544

Adverse event: discharge

Adverse event: discharge

Adverse event: discharge

Adverse event: discharge
Study: 19948614

Adverse event: incontinence

Adverse event: pain

Adverse event: abdominal pain
Study: 17515461

Adverse event: death

Adverse event: death

Adverse event: death

Adverse event: death
Study: 9679846

Adverse event: tryptase
Study: 2686995

Adverse event: barium meal

Adverse event: barium meal
Study: 4237796

Adverse event: acne
Study: 31523801

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 23254324

Adverse event: pain

Adverse event: discharge

Adverse event: pain

Adverse event: discharge
Study: 21598351

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction
Study: 16784086

Adverse event: prosthetic valve endocarditis

Adverse event: endocarditis

Adverse event: surgery
Study: 1530680

Adverse event: mucosal irritation

Adverse event: mucosal irritation
Study: 29338801

Adverse event: underweight
Study: 23743487

Adverse event: discharge

Adverse event: weight

Adverse event: discharge

Adverse event: discharge

Adverse event: weight
Study: 16896912

Adverse event: neutrophil count

Adverse event: lymphoma
Study: 14504150

Adverse event: extubation

Adverse event: extubation

Adverse event: discharge

Adverse event: discharge
Study: 7024866

Adverse event: rheumatoid arthritis

Adverse event: arthritis

Adverse event: rheumatoid arthritis

Adverse event: arthritis
Study: 31512024

Adverse event: pain

Adverse event: pain

Adverse event: delivery

Adverse event: surgery

Adverse event: wound drainage

Adverse event: wound

Adverse event: drainage
Study: 27760701

Adverse event: psychotic disorder

Adverse event: psychotic disorder
Study: 25242460

Adverse event: surgery
Study: 22843310

Adverse event: trismus

Adverse event: pain

Adverse event: swelling
Study: 16863608

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction
Study: 12623291

Adverse event: chondropathy

Adverse event: chondropathy

Adverse event: chondropathy
Study: 30464447

Adverse event: pneumonia

Adverse event: adverse event
Study: 27585745

Adverse event: caregiver
Study: 24439986

Adverse event: death

Adverse event: myocardial infarction

Adverse event: cardiac death

Adverse event: infarction

Adverse event: death

Adverse event: myocardial infarction

Adverse event: cardiac death

Adverse event: infarction
Study: 22749688

Adverse event: mass
Study: 20215553

Adverse event: weight

Adverse event: obesity

Adverse event: weight
Study: 18751649

Adverse event: pain

Adverse event: pain management
Study: 30366971

Adverse event: hypopnoea

Adverse event: apnoea
Study: 30346543

Adverse event: discharge
Study: 27183835

Adverse event: pain

Adverse event: radiculopathy
Study: 24840045

Adverse event: weight
Study: 23180252

Adverse event: resuscitation

Adverse event: resuscitation
Study: 18695931

Adverse event: heart rate

Adverse event: heart rate

Adverse event: heart rate

Adverse event: heart rate
Study: 10335758

Adverse event: sinus rhythm
Study: 11962676

Adverse event: metastases
Study: 6366419

Adverse event: necrosis

Adverse event: fall
Study: 31060890

Adverse event: stress
Study: 24885904

Adverse event: depression

Adverse event: anger

Adverse event: depression

Adverse event: anger
Study: 15811926

Adverse event: infusion

Adverse event: infusion
Study: 8845292

Adverse event: heart rate
Study: 2353864

Adverse event: low density lipoprotein

Adverse event: apolipoprotein b

Adverse event: apolipoprotein

Adverse event: high density lipoprotein

Adverse event: apolipoprotein

Adverse event: high density lipoprotein

Adverse event: low density lipoprotein

Adverse event: high density lipoprotein
Study: 31558739

Adverse event: weight
Study: 25885010

Adverse event: schizophrenia

Adverse event: anxiety
Study: 24499495

Adverse event: piloerection

Adverse event: heart rate

Adverse event: paraesthesia
Study: 22034996

Adverse event: procedural complication

Adverse event: procedural complication
Study: 17595419

Adverse event: muscle mass

Adverse event: mass

Adverse event: muscle mass

Adverse event: mass
Study: 31243228

Adverse event: pain
Study: 8207741

Adverse event: heart rate

Adverse event: heart rate
Study: 2928444

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 810098

Adverse event: necrosis

Adverse event: cardiac failure

Adverse event: pain

Adverse event: electrocardiogram
Study: 31243228

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 24824157

Adverse event: oxytocin

Adverse event: delivery

Adverse event: oxytocin

Adverse event: delivery
Study: 22056739

Adverse event: death

Adverse event: metastasis
Study: 16569546

Adverse event: fall
Study: 12756094

Adverse event: atrophy

Adverse event: burning sensation
Study: 9071201

Adverse event: pain

Adverse event: pain
Study: 8369985

Adverse event: hydroxyproline

Adverse event: osteocalcin

Adverse event: hydroxyproline

Adverse event: osteocalcin
Study: 27049290

Adverse event: pco2
Study: 18795656

Adverse event: atrophy

Adverse event: hypersplenism

Adverse event: splenectomy
Study: 17012105

Adverse event: inflammation
Study: 12952774

Adverse event: anxiety

Adverse event: heart rate

Adverse event: respiratory rate
Study: 11084174

Adverse event: postoperative analgesia

Adverse event: pain

Adverse event: postoperative analgesia

Adverse event: pain
Study: 9080525

Adverse event: syncope

Adverse event: syncope
Study: 29787547

Adverse event: hernia

Adverse event: incisional hernia

Adverse event: hernia

Adverse event: incisional hernia

Adverse event: dehiscence

Adverse event: dehiscence

Adverse event: infection

Adverse event: infection
Study: 26668251

Adverse event: neutropenia

Adverse event: neutropenia

Adverse event: neutropenia
Study: 7926702

Adverse event: tinnitus

Adverse event: depression
Study: 22911148

Adverse event: fasting

Adverse event: fasting

Adverse event: weight

Adverse event: body mass index

Adverse event: mass
Study: 15182266

Adverse event: hyperglycaemia

Adverse event: pneumonia

Adverse event: respiratory failure

Adverse event: oxygen therapy
Study: 11680329

Adverse event: uterine hyperstimulation

Adverse event: caesarean section
Study: 9675624

Adverse event: weight

Adverse event: heart rate decreased

Adverse event: heart rate
Study: 25209926

Adverse event: delivery
Study: 7926702

Adverse event: illness

Adverse event: tinnitus
Study: 31464581

Adverse event: pain

Adverse event: headache

Adverse event: pain

Adverse event: headache
Study: 28459835

Adverse event: heart rate
Study: 25209926

Adverse event: progesterone

Adverse event: progesterone

Adverse event: delivery

Adverse event: progesterone

Adverse event: delivery

Adverse event: delivery

Adverse event: progesterone

Adverse event: progesterone
Study: 21349646

Adverse event: pain

Adverse event: pain
Study: 19906334

Adverse event: pain

Adverse event: diarrhoea

Adverse event: discharge

Adverse event: nausea

Adverse event: depression

Adverse event: anxiety
Study: 11780880

Adverse event: compulsions

Adverse event: compulsions
Study: 9137509

Adverse event: adjuvant therapy

Adverse event: metastasis
Study: 8106223

Adverse event: vomiting

Adverse event: nausea
Study: 3661963

Adverse event: amnesia

Adverse event: sedation

Adverse event: discharge

Adverse event: sedation
Study: 31376290

Adverse event: periodontitis

Adverse event: periodontitis
Study: 19076173

Adverse event: weight

Adverse event: surgery
Study: 16960941

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 11789281

Adverse event: pulmonary arterial pressure

Adverse event: angiotensin ii
Study: 9089558

Adverse event: skin irritation

Adverse event: skin irritation

Adverse event: pruritus

Adverse event: pruritus

Adverse event: adhesion

Adverse event: adhesion
Study: 3535010

Adverse event: ulcer

Adverse event: ulcer
Study: 30295410

Adverse event: pain

Adverse event: amnesia

Adverse event: sedation

Adverse event: pain

Adverse event: amnesia

Adverse event: sedation
Study: 26661319

Adverse event: ejection fraction
Study: 22429325

Adverse event: weight

Adverse event: weight
Study: 9647268

Adverse event: asthma
Study: 18804887

Adverse event: illness

Adverse event: illness
Study: 15690537

Adverse event: biopsy

Adverse event: biopsy

Adverse event: biopsy

Adverse event: biopsy

Adverse event: diabetes mellitus

Adverse event: diabetes mellitus

Adverse event: cytomegalovirus infection

Adverse event: infection

Adverse event: cytomegalovirus infection

Adverse event: infection
Study: 12918131

Adverse event: pain

Adverse event: abdominal pain
Study: 30654026

Adverse event: weight
Study: 25256361

Adverse event: depression
Study: 23895180

Adverse event: vomiting
Study: 21439633

Adverse event: death

Adverse event: injury

Adverse event: death

Adverse event: death

Adverse event: injury
Study: 17164546

Adverse event: necrosis

Adverse event: abscess

Adverse event: pancreatic abscess

Adverse event: organ failure

Adverse event: necrosis

Adverse event: abscess

Adverse event: pancreatic abscess

Adverse event: organ failure
Study: 10889424

Adverse event: glare

Adverse event: glare
Study: 29348010

Adverse event: regurgitation
Study: 27172483

Adverse event: death

Adverse event: death

Adverse event: disease progression

Adverse event: chemotherapy

Adverse event: disease progression
Study: 21959100

Adverse event: wound
Study: 19659665

Adverse event: prophylaxis

Adverse event: prophylaxis
Study: 16005976

Adverse event: glare

Adverse event: glare
Study: 10604042

Adverse event: pain

Adverse event: pain
Study: 1682226

Adverse event: sedation
Study: 30245281

Adverse event: pain
Study: 7137521

Adverse event: rhinomanometry

Adverse event: rhinomanometry
Study: 30245281

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: nausea

Adverse event: adverse event
Study: 26916487

Adverse event: pneumonia
Study: 25230866

Adverse event: infection

Adverse event: mechanical ventilation

Adverse event: infection

Adverse event: mechanical ventilation
Study: 17480223

Adverse event: bowel preparation

Adverse event: discomfort

Adverse event: bowel preparation

Adverse event: pain

Adverse event: nausea
Study: 14997083

Adverse event: bispectral index

Adverse event: heart rate
Study: 11642080

Adverse event: heart rate

Adverse event: heart rate
Study: 2480576

Adverse event: infusion
Study: 25660106

Adverse event: pain

Adverse event: photodynamic therapy
Study: 22968058

Adverse event: pain
Study: 17961086

Adverse event: infection
Study: 12134984

Adverse event: wound

Adverse event: dellen
Study: 491472

Adverse event: epinephrine

Adverse event: epinephrine
Study: 15308881

Adverse event: hypertension
Study: 10401453

Adverse event: stress

Adverse event: personality disorder
Study: 2213868

Adverse event: alcohol use

Adverse event: sexually active
Study: 28432376

Adverse event: heart rate

Adverse event: stress

Adverse event: heart rate

Adverse event: stress

Adverse event: heart rate

Adverse event: stress
Study: 20437680

Adverse event: hypoxia

Adverse event: hypoxia
Study: 17984856

Adverse event: stress

Adverse event: anxiety

Adverse event: schizophrenia
Study: 26244563

Adverse event: pain
Study: 16319406

Adverse event: weight
Study: 10548627

Adverse event: pregnancy

Adverse event: pregnancy
Study: 8847279

Adverse event: infant
Study: 1973879

Adverse event: weight
Study: 27395330

Adverse event: constipation

Adverse event: dyspepsia

Adverse event: vomiting

Adverse event: nausea
Study: 26244563

Adverse event: pain

Adverse event: pain
Study: 24862330

Adverse event: neutrophil chemotaxis
Study: 11020409

Adverse event: posterior capsule opacification

Adverse event: posterior capsule opacification

Adverse event: posterior capsule opacification
Study: 6407293

Adverse event: exercise test
Study: 30520243

Adverse event: weight

Adverse event: overweight

Adverse event: fasting

Adverse event: weight

Adverse event: overweight

Adverse event: weight

Adverse event: overweight

Adverse event: waist circumference
Study: 26101175

Adverse event: weight

Adverse event: fasting

Adverse event: weight

Adverse event: fasting

Adverse event: weight

Adverse event: fasting
Study: 24339309

Adverse event: agitation

Adverse event: agitation

Adverse event: pain

Adverse event: pain

Adverse event: discharge

Adverse event: discharge

Adverse event: mean arterial pressure

Adverse event: heart rate

Adverse event: surgery

Adverse event: mean arterial pressure

Adverse event: heart rate
Study: 15143450

Adverse event: discomfort
Study: 11435967

Adverse event: dialysis

Adverse event: graft loss

Adverse event: dialysis

Adverse event: graft loss
Study: 9740480

Adverse event: cardiac output

Adverse event: cardiac output
Study: 26076572

Adverse event: pain

Adverse event: surgery

Adverse event: rash
Study: 16832632

Adverse event: biopsy

Adverse event: radiotherapy
Study: 2156644

Adverse event: depression
Study: 6249334

Adverse event: sedation
Study: 28682286

Adverse event: pain

Adverse event: burning sensation
Study: 21554549

Adverse event: adverse event

Adverse event: adverse event

Adverse event: adverse event
Study: 19135922

Adverse event: pain

Adverse event: breast pain
Study: 11465311

Adverse event: infection

Adverse event: infection
Study: 8442965

Adverse event: pain

Adverse event: extubation

Adverse event: surgery

Adverse event: retching

Adverse event: vomiting
Study: 2878942

Adverse event: anxiety

Adverse event: tension
Study: 30817785

Adverse event: fatigue