Study: NCT04616430

Adverse event: Rapid heart rate or palpitations
Serious: no
Organ System: Cardiac disorders
Frequency: 13 affected / 30 at risk

Adverse event: Feel lightheaded (dizzy)
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 14 affected / 30 at risk

Adverse event: Eyesight changes
Serious: no
Organ System: Eye disorders
Frequency: 9 affected / 30 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 30 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 30 at risk

Adverse event: Difficulty swallowing
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 30 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 30 at risk

Adverse event: Feel bloated
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 13 affected / 30 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 30 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 30 at risk

Adverse event: Burning feeling from breast tissue or breast skin
Serious: no
Organ System: General disorders
Frequency: 6 affected / 30 at risk

Adverse event: Fragile mucous membranes
Serious: no
Organ System: General disorders
Frequency: 18 affected / 30 at risk

Adverse event: Irritation from the breast skin
Serious: no
Organ System: General disorders
Frequency: 8 affected / 30 at risk

Adverse event: Itching from the breast skin
Serious: no
Organ System: General disorders
Frequency: 6 affected / 30 at risk

Adverse event: Lack of energy
Serious: no
Organ System: General disorders
Frequency: 3 affected / 30 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Frequency: 4 affected / 30 at risk

Adverse event: Pain from breast tissue or breast skin
Serious: no
Organ System: General disorders
Frequency: 3 affected / 30 at risk

Adverse event: Redness on breast skin
Serious: no
Organ System: General disorders
Frequency: 4 affected / 30 at risk

Adverse event: Swelling of arms or legs
Serious: no
Organ System: General disorders
Frequency: 2 affected / 30 at risk

Adverse event: Weight increased
Serious: no
Organ System: Investigations
Frequency: 15 affected / 30 at risk

Adverse event: Lack of appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 30 at risk

Adverse event: Muscle cramps (e.g. in legs)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 18 affected / 30 at risk

Adverse event: Pain in joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 14 affected / 30 at risk

Adverse event: Difficulty concentrating
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 30 at risk

Adverse event: Feeling drowsy
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 30 at risk

Adverse event: Headaches
Serious: no
Organ System: Nervous system disorders
Frequency: 17 affected / 30 at risk

Adverse event: Numbness/tingling in the hands and feet
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 30 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 13 affected / 30 at risk

Adverse event: Depressed mood
Serious: no
Organ System: Psychiatric disorders
Frequency: 4 affected / 30 at risk

Adverse event: Irritability
Serious: no
Organ System: Psychiatric disorders
Frequency: 9 affected / 30 at risk

Adverse event: Mood swings
Serious: no
Organ System: Psychiatric disorders
Frequency: 8 affected / 30 at risk

Adverse event: Libido decreased
Serious: no
Organ System: Psychiatric disorders
Frequency: 23 affected / 30 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 6 affected / 30 at risk

Adverse event: Breast sensitivity/tenderness
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 8 affected / 30 at risk

Adverse event: Vulvovaginal dryness
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 22 affected / 30 at risk

Adverse event: Menopausal symptoms
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 19 affected / 30 at risk

Adverse event: Night sweats
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 21 affected / 30 at risk

Adverse event: Dyspareunia
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 19 affected / 30 at risk

Adverse event: Vaginal bleeding or spotting
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 30 at risk

Adverse event: Vaginal discharge
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 10 affected / 30 at risk

Adverse event: Vaginal itching/irritation
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 5 affected / 30 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 30 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 30 at risk

Adverse event: Cold sweat
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 5 affected / 30 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 9 affected / 30 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 4 affected / 30 at risk

Adverse event: Rashes on breast skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 12 affected / 30 at risk

Adverse event: Skin rashes
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 13 affected / 30 at risk

Adverse event: Rapid heart rate or palpitations
Serious: no
Organ System: Cardiac disorders
Frequency: 3 affected / 30 at risk

Adverse event: Feel lightheaded (dizzy)
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 10 affected / 30 at risk

Adverse event: Eyesight changes
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 30 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 30 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 30 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 30 at risk

Adverse event: Feel bloated
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 10 affected / 30 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 30 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 30 at risk

Adverse event: Burning feeling from breast tissue or breast skin
Serious: no
Organ System: General disorders
Frequency: 5 affected / 30 at risk

Adverse event: Fragile mucous membranes
Serious: no
Organ System: General disorders
Frequency: 14 affected / 30 at risk

Adverse event: Irritation from the breast skin
Serious: no
Organ System: General disorders
Frequency: 12 affected / 30 at risk

Adverse event: Itching from the breast skin
Serious: no
Organ System: General disorders
Frequency: 21 affected / 30 at risk

Adverse event: Lack of energy
Serious: no
Organ System: General disorders
Frequency: 6 affected / 30 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Frequency: 3 affected / 30 at risk

Adverse event: Pain from breast tissue or breast skin
Serious: no
Organ System: General disorders
Frequency: 4 affected / 30 at risk

Adverse event: Redness on breast skin
Serious: no
Organ System: General disorders
Frequency: 9 affected / 30 at risk

Adverse event: Weight increased
Serious: no
Organ System: Investigations
Frequency: 9 affected / 30 at risk

Adverse event: Muscle cramps (e.g. in legs)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 11 affected / 30 at risk

Adverse event: Pain in joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 10 affected / 30 at risk

Adverse event: Feeling drowsy
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 30 at risk

Adverse event: Headaches
Serious: no
Organ System: Nervous system disorders
Frequency: 11 affected / 30 at risk

Adverse event: Numbness/tingling in the hands and feet
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 30 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 9 affected / 30 at risk

Adverse event: Feeling nervous
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 30 at risk

Adverse event: Depressed mood
Serious: no
Organ System: Psychiatric disorders
Frequency: 3 affected / 30 at risk

Adverse event: Irritability
Serious: no
Organ System: Psychiatric disorders
Frequency: 10 affected / 30 at risk

Adverse event: Mood swings
Serious: no
Organ System: Psychiatric disorders
Frequency: 9 affected / 30 at risk

Adverse event: Libido decreased
Serious: no
Organ System: Psychiatric disorders
Frequency: 19 affected / 30 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 30 at risk

Adverse event: Problems with urination
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 30 at risk

Adverse event: Breast sensitivity/tenderness
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 8 affected / 30 at risk

Adverse event: Vulvovaginal dryness
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 22 affected / 30 at risk

Adverse event: Menopausal symptoms
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 14 affected / 30 at risk

Adverse event: Night sweats
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 13 affected / 30 at risk

Adverse event: Dyspareunia
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 16 affected / 30 at risk

Adverse event: Vaginal bleeding or spotting
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 2 affected / 30 at risk

Adverse event: Vaginal discharge
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 9 affected / 30 at risk

Adverse event: Vaginal itching/irritation
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 6 affected / 30 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 30 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 30 at risk

Adverse event: Cold sweat
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 4 affected / 30 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 9 affected / 30 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 8 affected / 30 at risk

Adverse event: Rashes on breast skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 21 affected / 30 at risk

Adverse event: Skin rashes
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 13 affected / 30 at risk

Adverse event: Rapid heart rate or palpitations
Serious: no
Organ System: Cardiac disorders
Frequency: 4 affected / 30 at risk

Adverse event: Feel lightheaded (dizzy)
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 4 affected / 30 at risk

Adverse event: Eyesight changes
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 30 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 30 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 30 at risk

Adverse event: Difficulty swallowing
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 30 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 30 at risk

Adverse event: Feel bloated
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 30 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 30 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 30 at risk

Adverse event: Burning feeling from breast tissue or breast skin
Serious: no
Organ System: General disorders
Frequency: 7 affected / 30 at risk

Adverse event: Fragile mucous membranes
Serious: no
Organ System: General disorders
Frequency: 14 affected / 30 at risk

Adverse event: Irritation from the breast skin
Serious: no
Organ System: General disorders
Frequency: 15 affected / 30 at risk

Adverse event: Itching from the breast skin
Serious: no
Organ System: General disorders
Frequency: 22 affected / 30 at risk

Adverse event: Lack of energy
Serious: no
Organ System: General disorders
Frequency: 3 affected / 30 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 30 at risk

Adverse event: Pain from breast tissue or breast skin
Serious: no
Organ System: General disorders
Frequency: 3 affected / 30 at risk

Adverse event: Redness on breast skin
Serious: no
Organ System: General disorders
Frequency: 9 affected / 30 at risk

Adverse event: Deviating lab value
Serious: no
Organ System: Investigations
Frequency: 1 affected / 30 at risk

Adverse event: Weight increased
Serious: no
Organ System: Investigations
Frequency: 4 affected / 30 at risk

Adverse event: Muscle cramps (e.g. in legs)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 11 affected / 30 at risk

Adverse event: Pain in joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 11 affected / 30 at risk

Adverse event: Difficulty concentrating
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 30 at risk

Adverse event: Feeling drowsy
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 30 at risk

Adverse event: Headaches
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 30 at risk

Adverse event: Numbness/tingling in the hands and feet
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 30 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 4 affected / 30 at risk

Adverse event: Feeling nervous
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 30 at risk

Adverse event: Depressed mood
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 30 at risk

Adverse event: Irritability
Serious: no
Organ System: Psychiatric disorders
Frequency: 5 affected / 30 at risk

Adverse event: Mood swings
Serious: no
Organ System: Psychiatric disorders
Frequency: 6 affected / 30 at risk

Adverse event: Libido decreased
Serious: no
Organ System: Psychiatric disorders
Frequency: 15 affected / 30 at risk

Adverse event: Problems with urination
Serious: no
Organ System: Renal and urinary disorders
Frequency: 2 affected / 30 at risk

Adverse event: Breast sensitivity/tenderness
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 8 affected / 30 at risk

Adverse event: Vulvovaginal dryness
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 13 affected / 30 at risk

Adverse event: Menopausal symptoms
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 16 affected / 30 at risk

Adverse event: Night sweats
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 14 affected / 30 at risk

Adverse event: Dyspareunia
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 14 affected / 30 at risk

Adverse event: Vaginal bleeding or spotting
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 2 affected / 30 at risk

Adverse event: Vaginal discharge
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 4 affected / 30 at risk

Adverse event: Vaginal itching/irritation
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 4 affected / 30 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 30 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 30 at risk

Adverse event: Cold sweat
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 30 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 8 affected / 30 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 12 affected / 30 at risk

Adverse event: Rashes on breast skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 26 affected / 30 at risk

Adverse event: Skin rashes
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 17 affected / 30 at risk