TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT00000125

Adverse event: Ocular Serious Adverse Events (OHTS I, June 2002)
Serious: yes
Organ System: Eye disorders
Notes: Specific ocular serious adverse events are unknown because they were only collected with regard to organ system.
Frequency: 12 affected / 819 at risk

Adverse event: Ocular Adverse Event (Not Serious)
Serious: no
Organ System: Eye disorders
Notes: Adverse Events that were not serious.
Frequency: 481 affected / 819 at risk

Adverse event: Ocular Serious Adverse Events (OHTS I, June 2002)
Serious: yes
Organ System: Eye disorders
Notes: Specific ocular serious adverse events are unknown because they were only collected with regard to organ system.
Frequency: 13 affected / 817 at risk

Adverse event: Ocular Adverse Event (Not Serious)
Serious: no
Organ System: Eye disorders
Notes: Adverse Events that were not serious.
Frequency: 570 affected / 817 at risk
Study: NCT00000134

Adverse event: Neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 32 affected / 88 at risk

Adverse event: Thrombocytopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 14 affected / 88 at risk

Adverse event: Hospitalizations
Serious: no
Organ System: Infections and infestations
Frequency: 7 affected / 88 at risk

Adverse event: Neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 41 affected / 93 at risk

Adverse event: Thrombocytopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 8 affected / 93 at risk

Adverse event: Hospitalizations
Serious: no
Organ System: Infections and infestations
Frequency: 7 affected / 93 at risk

Adverse event: Neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 51 affected / 93 at risk

Adverse event: Thrombocytopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 15 affected / 93 at risk

Adverse event: Hospitalizations
Serious: no
Organ System: Infections and infestations
Frequency: 10 affected / 93 at risk
Study: NCT00000136

Adverse event: Opportunistic infection
Serious: yes
Organ System: Immune system disorders
Frequency: 60 affected / 107 at risk

Adverse event: Opportunistic infection
Serious: yes
Organ System: Immune system disorders
Frequency: 73 affected / 127 at risk
Study: NCT00000142

Adverse event: Proteinuria 2+
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 26 at risk

Adverse event: Proteinuria 2+
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 13 affected / 26 at risk

Adverse event: Serum creatinine level >= 133 umol/L (1.5 mg/dL)
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 26 at risk

Adverse event: Proteinuria 2+
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 8 affected / 12 at risk

Adverse event: Serum creatinine level >= 133 umol/L (1.5 mg/dL)
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 12 at risk
Study: NCT00000378

Adverse event: Orthostatic hypotension
Serious: no
Organ System: Cardiac disorders
Frequency: 2 affected / 58 at risk

Adverse event: Orthostatic hypotension
Serious: no
Organ System: Cardiac disorders
Frequency: 4 affected / 52 at risk
Study: NCT00000392

Adverse event: Death
Serious: yes
Organ System: Immune system disorders
Frequency: 8 affected / 106 at risk

Adverse event: Depression or Irritability
Serious: no
Organ System: Psychiatric disorders
Frequency: 7 affected / 106 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 34 affected / 106 at risk

Adverse event: Nasal congestion
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 12 affected / 106 at risk

Adverse event: Proteinuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 18 affected / 106 at risk

Adverse event: Eosinophilia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 4 affected / 106 at risk

Adverse event: Death
Serious: yes
Organ System: Immune system disorders
Frequency: 3 affected / 109 at risk

Adverse event: Depression or Irritability
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 109 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 42 affected / 109 at risk

Adverse event: Nasal congestion
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 5 affected / 109 at risk

Adverse event: Proteinuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 9 affected / 109 at risk
Study: NCT00000479

Adverse event: Haemorrhagic stroke
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 27 affected / 9968 at risk

Adverse event: Haematuria
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1534 affected / 9968 at risk

Adverse event: easy bruising
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 5297 affected / 9968 at risk

Adverse event: Epistaxis
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1854 affected / 9968 at risk

Adverse event: report of GI upset
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5969 affected / 9968 at risk

Adverse event: Haemorrhagic stroke
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 20 affected / 9971 at risk

Adverse event: Haematuria
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1467 affected / 9971 at risk

Adverse event: easy bruising
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 4247 affected / 9971 at risk

Adverse event: Epistaxis
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1703 affected / 9971 at risk

Adverse event: report of GI upset
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5915 affected / 9971 at risk

Adverse event: Haemorrhagic stroke
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 24 affected / 9966 at risk

Adverse event: Haematuria
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1505 affected / 9966 at risk

Adverse event: easy bruising
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 5263 affected / 9966 at risk

Adverse event: Epistaxis
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1947 affected / 9966 at risk

Adverse event: report of GI upset
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5887 affected / 9966 at risk

Adverse event: Haemorrhagic stroke
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 21 affected / 9971 at risk

Adverse event: Haematuria
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1411 affected / 9971 at risk

Adverse event: easy bruising
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 4247 affected / 9971 at risk

Adverse event: Epistaxis
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1618 affected / 9971 at risk

Adverse event: report of GI upset
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 6000 affected / 9971 at risk
Study: NCT00000575

Adverse event: Phsychiatric (behavior)
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 311 at risk

Adverse event: Asthma exacerbation
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 312 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 312 at risk

Adverse event: Musculoskeletal (low bone mineral density, back pain)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 312 at risk

Adverse event: Phsychiatric (behavior)
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 312 at risk

Adverse event: Respiratory (cough, wheeze, chest tightness, croup)
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 5 affected / 312 at risk

Adverse event: Asthma exacerbation
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 418 at risk

Adverse event: Psychiatric (hallucinations)
Serious: yes
Organ System: Psychiatric disorders
Frequency: 2 affected / 418 at risk

Adverse event: Nephrolithiasis
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 418 at risk

Adverse event: Musculoskeletal (low bone mineral density, back pain)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 418 at risk

Adverse event: Respiratory (cough, wheeze, chest tightness, croup)
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 418 at risk
Study: NCT00001259

Adverse event: Paraesthesia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 58 at risk

Adverse event: Fluid retention
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 58 at risk

Adverse event: Mood disorder due to a general medical condition
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 58 at risk

Adverse event: Genital atrophy
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 58 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Frequency: 2 affected / 48 at risk

Adverse event: Gastritis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 48 at risk
Study: NCT00001262

Adverse event: Death
Serious: yes
Organ System: Nervous system disorders
Notes: Menkes disease
Frequency: 10 affected / 35 at risk

Adverse event: Dehydration
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 35 at risk

Adverse event: Death
Serious: yes
Organ System: Nervous system disorders
Notes: Menkes disease
Frequency: 11 affected / 22 at risk
Study: NCT00001277

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 19 at risk
Study: NCT00001305

Adverse event: Suicide attempt
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 42 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 42 at risk

Adverse event: Reaction to preservatives
Serious: no
Organ System: Immune system disorders
Frequency: 1 affected / 42 at risk
Study: NCT00001322

Adverse event: Breast fibroma
Serious: yes
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 92 at risk

Adverse event: Epigastric discomfort
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 92 at risk

Adverse event: Pain in extremity
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 82 at risk
Study: NCT00001656

Adverse event: Abnormal white blood count
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Total white blood count \> 2000; absolute neutrophil count between 1000 and 1500
Frequency: 1 affected / 13 at risk

Adverse event: Enuresis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 13 at risk

Adverse event: Increased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 13 at risk

Adverse event: Salivary hypersecretion
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 13 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 13 at risk

Adverse event: Difficulty concentrating
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 13 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 13 at risk

Adverse event: Insomnia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 13 at risk

Adverse event: Hypertension
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 11 at risk

Adverse event: tachycardia >100 beats/min (supine)
Serious: no
Organ System: Cardiac disorders
Frequency: 2 affected / 12 at risk

Adverse event: Abnormal white blood count
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Total white blood count \> 2000; absolute neutrophil count between 1000 and 1500
Frequency: 2 affected / 12 at risk

Adverse event: Enuresis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 5 affected / 12 at risk

Adverse event: Increased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 12 at risk

Adverse event: Salivary hypersecretion
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 8 affected / 12 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 12 at risk

Adverse event: Difficulty concentrating
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 12 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 12 at risk

Adverse event: Insomnia
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 12 at risk

Adverse event: Hypertension
Serious: no
Organ System: Cardiac disorders
Frequency: 7 affected / 11 at risk

Adverse event: tachycardia >100 beats/min (supine)
Serious: no
Organ System: Cardiac disorders
Frequency: 7 affected / 10 at risk

Adverse event: Tachycardia >120 beats/min (supine)
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 10 at risk
Study: NCT00001703

Adverse event: Fatigue
Serious: yes
Organ System: General disorders
Frequency: 5 affected / 6 at risk

Adverse event: Injection site reaction
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 5 affected / 6 at risk

Adverse event: Headaches
Serious: yes
Organ System: Nervous system disorders
Frequency: 4 affected / 6 at risk

Adverse event: myalgia/arthralgia
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 6 at risk

Adverse event: Pyrexia
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 6 at risk

Adverse event: Nasal congestion
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 6 at risk

Adverse event: Hyperglycaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 6 at risk

Adverse event: Hypernatraemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 6 at risk

Adverse event: Hypocalcaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 6 at risk

Adverse event: Rhinitis allergic
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 6 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 5 affected / 6 at risk

Adverse event: Injection site reaction
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 5 affected / 6 at risk
Study: NCT00001880

Adverse event: Mucositis with fever
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 42 at risk

Adverse event: Pseudomonas sepsis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 42 at risk

Adverse event: Parainfluenza pneumonia and septic shock
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 42 at risk

Adverse event: Pulmonary aspergillus
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 42 at risk

Adverse event: Dyspnea with progressive mets to lungs
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 42 at risk

Adverse event: Faecaloma
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 42 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 42 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 42 at risk

Adverse event: Progressive disease
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 12 affected / 42 at risk

Adverse event: Acute Graft VS Host Disease of GI Tract
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 42 at risk

Adverse event: Cytomegalovirus colitis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 42 at risk

Adverse event: Invasive fungal infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 42 at risk

Adverse event: Acute nephrotoxicity
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 42 at risk

Adverse event: Acute Respiratory Distress
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 42 at risk

Adverse event: Hepatic failure
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 42 at risk

Adverse event: Cystitis haemorrhagic
Serious: no
Organ System: Renal and urinary disorders
Frequency: 4 affected / 42 at risk

Adverse event: Cytomegalovirus disease
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 42 at risk
Study: NCT00001959

Adverse event: Death (unrelated to the trial)
Serious: yes
Organ System: Injury, poisoning and procedural complications
Notes: traumatic subdural hematoma
Frequency: 1 affected / 21 at risk

Adverse event: Colon cancer (unrelated to the trial)
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 21 at risk

Adverse event: elevated liver enzymes (judged possibly related to the trial)
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 21 at risk

Adverse event: Abdominal discomfort
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 8 affected / 21 at risk

Adverse event: Sedation or fatigue
Serious: no
Organ System: General disorders
Frequency: 6 affected / 21 at risk

Adverse event: photosensitivity dermatitis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 21 at risk
Study: NCT00001984

Adverse event: Allograft Rejection
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 5 affected / 5 at risk

Adverse event: postbiopsy hemodynamically significant renal arteriovenous fistula
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 5 at risk

Adverse event: Grade II chronic allograft nepharopathy with proteinuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 2 affected / 5 at risk

Adverse event: Grade II CAN at year 1 post operation
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 5 at risk

Adverse event: OKT3 rescue requirement
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 5 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 5 affected / 5 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 5 affected / 5 at risk
Study: NCT00002540

Adverse event: Anxiety
Serious: no
Organ System: General disorders
Frequency: 1 affected / 38340 at risk

Adverse event: Haemorrhage
Serious: no
Organ System: General disorders
Frequency: 3 affected / 38340 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 101 affected / 38340 at risk

Adverse event: Fainted
Serious: no
Organ System: General disorders
Frequency: 58 affected / 38340 at risk

Adverse event: Inflammation
Serious: no
Organ System: General disorders
Frequency: 2 affected / 38340 at risk

Adverse event: Nausea
Serious: no
Organ System: General disorders
Frequency: 1 affected / 38340 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Frequency: 11 affected / 38340 at risk

Adverse event: Contusion
Serious: no
Organ System: General disorders
Frequency: 182 affected / 38340 at risk

Adverse event: Haematoma
Serious: no
Organ System: General disorders
Frequency: 187 affected / 38340 at risk
Study: NCT00002850

Adverse event: Death
Serious: yes
Organ System: General disorders
Notes: Hospitalized for evaluation of pain, shortness of breath, cough; death
Frequency: 1 affected / 69 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: no
Organ System: Gastrointestinal disorders
Notes: Hospitalized with GI bleed
Frequency: 1 affected / 69 at risk

Adverse event: Renal failure
Serious: yes
Organ System: Renal and urinary disorders
Notes: Hospitalized for acute renal failure
Frequency: 1 affected / 76 at risk

Adverse event: Infection, thrush, allergic reaction
Serious: yes
Organ System: Infections and infestations
Notes: Hospitalized for bacterial infection, oral thrush, allergic reaction to sulfa
Frequency: 1 affected / 76 at risk

Adverse event: Candida infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 76 at risk
Study: NCT00002981

Adverse event: Confusional state
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 173 at risk

Adverse event: Fatigue
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 173 at risk

Adverse event: Renal failure
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 173 at risk
Study: NCT00003199

Adverse event: Prolonged hospitalization for post-transplant complications
Serious: yes
Organ System: Infections and infestations
Notes: Transplant toxicity.
Frequency: 1 affected / 50 at risk

Adverse event: Pulmonary Emboli
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: IL-2/GM-CSF toxicity.
Frequency: 1 affected / 50 at risk

Adverse event: Myelosuppression
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Toxicity to transplant therapy. No deaths in 1st 100 days post-transplant.
Frequency: 50 affected / 50 at risk

Adverse event: Infections
Serious: no
Organ System: Infections and infestations
Notes: Toxicity to transplant therapy. No deaths in 1st 100 days post-transplant.
Frequency: 16 affected / 50 at risk

Adverse event: Hematologic
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Toxicity to IL-2/GM-CSF Therapy. No deaths on therapy.
Frequency: 6 affected / 28 at risk

Adverse event: Infection
Serious: no
Organ System: Infections and infestations
Notes: Toxicity to IL-2/GM-CSF Therapy. No deaths on therapy.
Frequency: 3 affected / 28 at risk