TrialPanorama/TrialPanorama-database huggingface dataset:
Study: 3132364

Adverse event: parenteral nutrition

Adverse event: parenteral nutrition
Study: 31645288

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: breast pain

Adverse event: pain

Adverse event: breast pain

Adverse event: pain

Adverse event: breast pain

Adverse event: pain

Adverse event: breast pain
Study: 25355797

Adverse event: injection

Adverse event: injection site reactions
Study: 24292351

Adverse event: weight

Adverse event: weight
Study: 10480191

Adverse event: high density lipoprotein

Adverse event: low density lipoprotein

Adverse event: apolipoprotein b

Adverse event: apolipoprotein
Study: 1906020

Adverse event: pregnancy

Adverse event: pregnancy

Adverse event: pregnancy
Study: 31344257

Adverse event: iontophoresis

Adverse event: iontophoresis

Adverse event: iontophoresis

Adverse event: iontophoresis
Study: 29807661

Adverse event: stress

Adverse event: stress

Adverse event: stress
Study: 18723296

Adverse event: necrosis

Adverse event: deafness
Study: 16925684

Adverse event: asthma

Adverse event: skin test

Adverse event: eosinophil cationic protein

Adverse event: injection
Study: 11322745

Adverse event: visual analogue scale
Study: 9165504

Adverse event: keratopathy

Adverse event: disease progression

Adverse event: nausea

Adverse event: keratopathy

Adverse event: nausea
Study: 8427853

Adverse event: protein c
Study: 2887102

Adverse event: cardiac index

Adverse event: norepinephrine

Adverse event: weight

Adverse event: norepinephrine increased

Adverse event: cardiac index

Adverse event: norepinephrine

Adverse event: weight

Adverse event: heart rate

Adverse event: norepinephrine increased

Adverse event: cardiac index

Adverse event: norepinephrine

Adverse event: weight

Adverse event: heart rate decreased

Adverse event: heart rate
Study: 22895351

Adverse event: heart rate

Adverse event: mass

Adverse event: bone loss
Study: 20683279

Adverse event: ecchymosis

Adverse event: ecchymosis

Adverse event: ecchymosis

Adverse event: ecchymosis
Study: 17910332

Adverse event: rhinitis

Adverse event: forced expiratory volume

Adverse event: asthma

Adverse event: forced expiratory volume

Adverse event: forced expiratory volume
Study: 11574763

Adverse event: thrombocytopenia

Adverse event: granulocytopenia

Adverse event: death

Adverse event: pneumonia
Study: 24679061

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: hypotension

Adverse event: hypotension

Adverse event: cardiac arrest

Adverse event: cardiac arrest
Study: 22642525

Adverse event: depression

Adverse event: anxiety
Study: 9270645

Adverse event: transfusion

Adverse event: transfusion

Adverse event: cardiopulmonary bypass

Adverse event: plasminogen activator inhibitor

Adverse event: plasmin inhibitor

Adverse event: plasminogen

Adverse event: plasminogen activator inhibitor

Adverse event: plasmin inhibitor

Adverse event: plasminogen
Study: 3130221

Adverse event: pregnancy

Adverse event: weight
Study: 23694782

Adverse event: irritability

Adverse event: depressed mood

Adverse event: restlessness

Adverse event: anxiety

Adverse event: increased appetite
Study: 22111972

Adverse event: oxygen saturation

Adverse event: oxygen saturation increased
Study: 16644323

Adverse event: ejection fraction

Adverse event: ejection fraction
Study: 12475575

Adverse event: tremor

Adverse event: palpitations

Adverse event: restlessness

Adverse event: headaches
Study: 10849527

Adverse event: cytogenetic response
Study: 31847977

Adverse event: pain

Adverse event: wound
Study: 27845510

Adverse event: endometrial ablation
Study: 21318582

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction
Study: 17867479

Adverse event: surgery

Adverse event: surgery

Adverse event: surgery
Study: 14741244

Adverse event: anxiety

Adverse event: anxiety
Study: 8150348

Adverse event: surgery

Adverse event: surgery

Adverse event: weight

Adverse event: weight
Study: 3179642

Adverse event: neuromas

Adverse event: cyst

Adverse event: scan

Adverse event: neuromas
Study: 31986989

Adverse event: obstruction

Adverse event: interactions
Study: 26721003

Adverse event: infection

Adverse event: wound

Adverse event: wound infection

Adverse event: infection

Adverse event: wound

Adverse event: wound infection
Study: 22332898

Adverse event: anxiety
Study: 21079955

Adverse event: scar

Adverse event: scar
Study: 19778479

Adverse event: pregnancy

Adverse event: pregnancy
Study: 14718419

Adverse event: discomfort

Adverse event: wound

Adverse event: infection

Adverse event: wound

Adverse event: wound infection
Study: 12872566

Adverse event: adrenalectomy

Adverse event: surgery

Adverse event: laparoscopy

Adverse event: robotic surgery

Adverse event: adrenalectomy

Adverse event: surgery

Adverse event: robotic surgery

Adverse event: laparoscopy

Adverse event: adrenalectomy

Adverse event: laparoscopy
Study: 26901417

Adverse event: discharge
Study: 22678875

Adverse event: pterygium
Study: 9501262

Adverse event: delirium

Adverse event: cerebral hypoperfusion

Adverse event: hypoperfusion

Adverse event: delirium

Adverse event: cerebral hypoperfusion

Adverse event: hypoperfusion
Study: 8580271

Adverse event: ulcer

Adverse event: duodenal ulcer

Adverse event: ulcer

Adverse event: duodenal ulcer

Adverse event: diarrhoea

Adverse event: diarrhoea
Study: 16438769

Adverse event: pain

Adverse event: conjunctival haemorrhage

Adverse event: akinesia

Adverse event: haemorrhage

Adverse event: pain

Adverse event: conjunctival haemorrhage

Adverse event: akinesia

Adverse event: haemorrhage
Study: 10865302

Adverse event: anxiety

Adverse event: anxiety
Study: 3030619

Adverse event: blood glucose

Adverse event: blood glucose decreased

Adverse event: blood glucose

Adverse event: blood glucose
Study: 28723717

Adverse event: visual analogue scale

Adverse event: osteoarthritis
Study: 6378236

Adverse event: infection
Study: 21933563

Adverse event: depression

Adverse event: depression
Study: 16611719

Adverse event: mass
Study: 12958324

Adverse event: fasting
Study: 17641927

Adverse event: oxygen saturation
Study: 25728553

Adverse event: pain

Adverse event: pain
Study: 21043369

Adverse event: pain
Study: 14990779

Adverse event: giardiasis
Study: 9406295

Adverse event: adhesion

Adverse event: extracorporeal circulation

Adverse event: extracorporeal circulation

Adverse event: hyperthermia

Adverse event: intensive care
Study: 7956628

Adverse event: weight
Study: 17919763

Adverse event: fasting
Study: 10392329

Adverse event: depression

Adverse event: depression

Adverse event: depression

Adverse event: dizziness
Study: 8888913

Adverse event: transferrin saturation

Adverse event: transferrin

Adverse event: serum ferritin
Study: 1986667

Adverse event: fall
Study: 6852361

Adverse event: cough

Adverse event: cough
Study: 30753216

Adverse event: chest pain

Adverse event: pain

Adverse event: chest pain

Adverse event: pain
Study: 27503018

Adverse event: fear

Adverse event: fear
Study: 22412169

Adverse event: blood glucose

Adverse event: body mass index

Adverse event: mass

Adverse event: high density lipoprotein

Adverse event: low density lipoprotein

Adverse event: fasting

Adverse event: apolipoprotein b

Adverse event: apolipoprotein

Adverse event: blood glucose

Adverse event: body mass index

Adverse event: mass

Adverse event: high density lipoprotein

Adverse event: low density lipoprotein

Adverse event: fasting

Adverse event: apolipoprotein b

Adverse event: apolipoprotein
Study: 10356104

Adverse event: hypertension
Study: 27765365

Adverse event: apolipoprotein

Adverse event: apolipoprotein b

Adverse event: apolipoprotein
Study: 22994843

Adverse event: depression

Adverse event: anxiety

Adverse event: stress

Adverse event: anxiety
Study: 12227126

Adverse event: fracture
Study: 9868644

Adverse event: fungal infection

Adverse event: infection
Study: 12227126

Adverse event: fractures
Study: 7993990

Adverse event: dizziness

Adverse event: discomfort

Adverse event: abdominal discomfort
Study: 31250938

Adverse event: palliative care

Adverse event: palliative care

Adverse event: palliative care

Adverse event: palliative care
Study: 25563311

Adverse event: eosinophil cationic protein

Adverse event: cough
Study: 23499539

Adverse event: heart rate

Adverse event: heart rate
Study: 17976988

Adverse event: neurotoxicity

Adverse event: vomiting

Adverse event: nausea
Study: 30217604

Adverse event: keratitis

Adverse event: surgery
Study: 15703953

Adverse event: pain
Study: 12510181

Adverse event: discharge
Study: 1629823

Adverse event: sciatica
Study: 10824627

Adverse event: bleeding time
Study: 20477825

Adverse event: haemoglobin

Adverse event: surgery
Study: 9793671

Adverse event: hypotension
Study: 7541158

Adverse event: infusion
Study: 27631775

Adverse event: nausea
Study: 2565210

Adverse event: glomerular filtration rate
Study: 27631775

Adverse event: adverse event

Adverse event: dermatitis

Adverse event: dermatitis

Adverse event: proctitis

Adverse event: proctitis

Adverse event: nausea

Adverse event: fatigue

Adverse event: fatigue

Adverse event: wound

Adverse event: wound
Study: 21220339

Adverse event: oxytocin

Adverse event: oxytocin
Study: 19762662

Adverse event: pregnancy

Adverse event: condom

Adverse event: pregnancy

Adverse event: condom
Study: 15459218

Adverse event: radiotherapy

Adverse event: metastases

Adverse event: radiotherapy

Adverse event: metastases
Study: 9557427

Adverse event: pain

Adverse event: paraesthesia

Adverse event: pain

Adverse event: paraesthesia
Study: 8345047

Adverse event: weight

Adverse event: acne
Study: 3725517

Adverse event: depression

Adverse event: depression
Study: 30476007

Adverse event: infection
Study: 30322392

Adverse event: free fatty acids
Study: 27010809

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: thrombosis
Study: 22732382

Adverse event: pruritus

Adverse event: pruritus

Adverse event: pruritus
Study: 19932545

Adverse event: pulse wave velocity

Adverse event: pulse wave velocity

Adverse event: pulse wave velocity
Study: 17368650

Adverse event: hyperphagia
Study: 8775399

Adverse event: malaise

Adverse event: malaise
Study: 6727750

Adverse event: influenza
Study: 3522159

Adverse event: fall

Adverse event: weight
Study: 28954840

Adverse event: weight

Adverse event: weight

Adverse event: weight

Adverse event: weight
Study: 23197844

Adverse event: low density lipoprotein

Adverse event: low density lipoprotein
Study: 21233091

Adverse event: weight

Adverse event: mean arterial pressure

Adverse event: oedema
Study: 12480972

Adverse event: visual analogue scale

Adverse event: fatigue

Adverse event: ejection fraction

Adverse event: glomerular filtration rate
Study: 11054618

Adverse event: death
Study: 1609038

Adverse event: depression

Adverse event: anxiety

Adverse event: depression

Adverse event: anxiety
Study: 31915146

Adverse event: obesity

Adverse event: obesity

Adverse event: obesity
Study: 30205315

Adverse event: pain

Adverse event: fatigue

Adverse event: vomiting

Adverse event: headache

Adverse event: nausea
Study: 25963932

Adverse event: depression

Adverse event: depression
Study: 24071616

Adverse event: discharge

Adverse event: pain

Adverse event: discharge

Adverse event: vomiting

Adverse event: nausea

Adverse event: discharge

Adverse event: discharge
Study: 22725946

Adverse event: fungal infection

Adverse event: infection

Adverse event: viral infection

Adverse event: bacterial infection

Adverse event: fungal infection

Adverse event: infection

Adverse event: viral infection

Adverse event: bacterial infection
Study: 18621090

Adverse event: delivery
Study: 14594516

Adverse event: constipation

Adverse event: pain

Adverse event: depression

Adverse event: respiratory depression
Study: 2127787

Adverse event: alanine aminotransferase

Adverse event: alanine aminotransferase

Adverse event: alanine aminotransferase

Adverse event: alanine aminotransferase

Adverse event: alanine aminotransferase
Study: 30832619

Adverse event: transplant
Study: 27801415

Adverse event: wound
Study: 31831295

Adverse event: international prostate symptom score
Study: 20640511

Adverse event: injection
Study: 17998490

Adverse event: carotene

Adverse event: carotene
Study: 14694248

Adverse event: nasal congestion
Study: 9704770

Adverse event: hypertension

Adverse event: gestational hypertension

Adverse event: hypertension

Adverse event: gestational hypertension
Study: 3288258

Adverse event: visual analogue scale

Adverse event: pain

Adverse event: bone pain

Adverse event: disease progression

Adverse event: hydroxyproline
Study: 26125538

Adverse event: fatigue

Adverse event: insomnia
Study: 24812897

Adverse event: irritability
Study: 22693734

Adverse event: asthenia

Adverse event: depression

Adverse event: asthenia
Study: 15569877

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death
Study: 8629589

Adverse event: mean arterial pressure

Adverse event: cardiac index

Adverse event: ejection fraction

Adverse event: heart rate

Adverse event: stroke volume
Study: 2123759

Adverse event: pregnancy

Adverse event: pregnancy

Adverse event: pregnancy
Study: 6769450

Adverse event: surgery

Adverse event: surgery
Study: 28891788

Adverse event: virologic failure
Study: 23827399

Adverse event: death

Adverse event: thrombosis

Adverse event: myocardial infarction

Adverse event: cardiac death

Adverse event: infarction

Adverse event: death
Study: 17323107

Adverse event: fracture
Study: 15127203

Adverse event: weight

Adverse event: weight
Study: 11436945

Adverse event: aspiration

Adverse event: injection
Study: 9878937

Adverse event: weight

Adverse event: infusion
Study: 102615

Adverse event: wound
Study: 31880734

Adverse event: pollution
Study: 31280096

Adverse event: disability
Study: 23497506

Adverse event: metabolic syndrome

Adverse event: metabolic syndrome
Study: 11165220

Adverse event: stress
Study: 8981711

Adverse event: retinopathy

Adverse event: vitrectomy

Adverse event: blindness

Adverse event: retinopathy
Study: 26282640

Adverse event: anxiety

Adverse event: anxiety

Adverse event: anxiety
Study: 24052026

Adverse event: anxiety

Adverse event: anxiety
Study: 15374558

Adverse event: retching

Adverse event: vomiting

Adverse event: nausea

Adverse event: nausea
Study: 3556338

Adverse event: ulcer
Study: 28733151

Adverse event: hunger

Adverse event: fasting

Adverse event: hunger

Adverse event: fasting
Study: 25911632

Adverse event: fatigue

Adverse event: fatigue

Adverse event: fatigue

Adverse event: fatigue
Study: 23137823

Adverse event: free fatty acids
Study: 21315217

Adverse event: discharge

Adverse event: discharge
Study: 17062807

Adverse event: overweight
Study: 10634735

Adverse event: peritonsillar abscess

Adverse event: abscess
Study: 8385164

Adverse event: low density lipoprotein
Study: 2908819

Adverse event: bradycardia

Adverse event: heart rate

Adverse event: heart rate
Study: 31904707

Adverse event: dependence

Adverse event: nicotine dependence

Adverse event: dependence

Adverse event: nicotine dependence
Study: 27599993

Adverse event: heart rate

Adverse event: heart rate
Study: 22986377

Adverse event: cough

Adverse event: visual analogue scale

Adverse event: cough

Adverse event: constipation

Adverse event: malaise

Adverse event: dizziness
Study: 19836155

Adverse event: proctitis
Study: 16101604

Adverse event: depression

Adverse event: pain

Adverse event: psychological abuse
Study: 12419717

Adverse event: pain
Study: 8549927

Adverse event: menopause

Adverse event: menopause
Study: 1683818

Adverse event: heart rate

Adverse event: hypotension

Adverse event: induction of anaesthesia

Adverse event: anaesthesia
Study: 7121808

Adverse event: heart rate
Study: 31288561

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction

Adverse event: death

Adverse event: myocardial infarction

Adverse event: infarction
Study: 25935943

Adverse event: migraine
Study: 22972771

Adverse event: tension

Adverse event: tension

Adverse event: interactions
Study: 19079814

Adverse event: aggression

Adverse event: depression

Adverse event: irritability

Adverse event: agitation

Adverse event: anxiety
Study: 11920308

Adverse event: infection

Adverse event: infection

Adverse event: infection

Adverse event: infection
Study: 10357377

Adverse event: infection
Study: 7573097

Adverse event: cytogenetic response

Adverse event: chemotherapy

Adverse event: chemotherapy

Adverse event: cytogenetic response
Study: 7381125

Adverse event: forced expiratory volume
Study: 30859377

Adverse event: death

Adverse event: myocardial infarction

Adverse event: cardiac death

Adverse event: infarction
Study: 9199073

Adverse event: hip arthroplasty

Adverse event: pain

Adverse event: knee arthroplasty
Study: 21649633

Adverse event: anxiety
Study: 19454025

Adverse event: malaria
Study: 9199073

Adverse event: pain
Study: 8482064

Adverse event: depression

Adverse event: insomnia

Adverse event: anxiety
Study: 30221864

Adverse event: hepatic encephalopathy

Adverse event: encephalopathy
Study: 20825316

Adverse event: infection

Adverse event: infection

Adverse event: infection

Adverse event: infection

Adverse event: infection

Adverse event: infection

Adverse event: wound

Adverse event: office visit

Adverse event: wound

Adverse event: office visit

Adverse event: infection

Adverse event: infection
Study: 16201125

Adverse event: death
Study: 12907329

Adverse event: oxygen saturation

Adverse event: heart rate
Study: 10388649

Adverse event: influenza

Adverse event: influenza
Study: 9116931

Adverse event: ejection fraction
Study: 6152029

Adverse event: elderly
Study: 31931269

Adverse event: discomfort
Study: 29397092

Adverse event: high density lipoprotein

Adverse event: low density lipoprotein
Study: 22215470

Adverse event: obesity
Study: 20481635

Adverse event: tension
Study: 6116296

Adverse event: asthma
Study: 30850941

Adverse event: poverty
Study: 21676011

Adverse event: body temperature

Adverse event: body temperature increased

Adverse event: body temperature

Adverse event: body temperature increased

Adverse event: body temperature

Adverse event: body temperature increased
Study: 19765496

Adverse event: weight

Adverse event: weight
Study: 17205438

Adverse event: nausea
Study: 11235719

Adverse event: cardiac index

Adverse event: injury

Adverse event: tension
Study: 1492864

Adverse event: depression

Adverse event: depression
Study: 31228760

Adverse event: pain

Adverse event: extubation

Adverse event: pain

Adverse event: extubation

Adverse event: pain

Adverse event: extubation
Study: 26192385

Adverse event: weight

Adverse event: weight

Adverse event: weight
Study: 21712301

Adverse event: discomfort
Study: 2147630

Adverse event: blood glucose
Study: 19788440

Adverse event: fraction of inspired oxygen

Adverse event: necrosis
Study: 18591307

Adverse event: incontinence

Adverse event: cough

Adverse event: stress

Adverse event: incontinence

Adverse event: cough

Adverse event: stress
Study: 19788440

Adverse event: fraction of inspired oxygen
Study: 2147630

Adverse event: injection

Adverse event: blood glucose

Adverse event: blood glucose

Adverse event: fasting

Adverse event: blood glucose

Adverse event: fasting

Adverse event: injection
Study: 28289894

Adverse event: inflammation
Study: 25879572

Adverse event: weight
Study: 22116961

Adverse event: bipolar disorder
Study: 17901084

Adverse event: gonorrhoea

Adverse event: trichomoniasis
Study: 9577354

Adverse event: scan
Study: 30629121

Adverse event: fall

Adverse event: fall
Study: 22104550

Adverse event: weight
Study: 19025407

Adverse event: nerve conduction studies
Study: 16875929

Adverse event: anxiety
Study: 10720170

Adverse event: vitamin a
Study: 30169405

Adverse event: vomiting

Adverse event: nausea
Study: 26275330

Adverse event: pregnancy

Adverse event: abortion

Adverse event: pregnancy

Adverse event: abortion
Study: 22009803

Adverse event: culture

Adverse event: blood culture

Adverse event: culture

Adverse event: blood culture
Study: 11693769

Adverse event: cardioversion
Study: 9038595

Adverse event: mass

Adverse event: mass
Study: 2892874

Adverse event: heart rate decreased

Adverse event: heart rate

Adverse event: heart rate decreased

Adverse event: heart rate

Adverse event: pain

Adverse event: heart rate

Adverse event: vital capacity
Study: 30020987

Adverse event: anxiety

Adverse event: depression

Adverse event: stress

Adverse event: anxiety
Study: 24554962

Adverse event: body temperature

Adverse event: body temperature
Study: 22854639

Adverse event: vitamin d
Study: 20231324

Adverse event: adverse event
Study: 19278081

Adverse event: dental plaque

Adverse event: dental plaque
Study: 15767536

Adverse event: weight

Adverse event: mass

Adverse event: weight

Adverse event: mass
Study: 30006327

Adverse event: stress

Adverse event: anxiety
Study: 27213613

Adverse event: pain

Adverse event: inflammation
Study: 23692706

Adverse event: cardiac output

Adverse event: heart rate

Adverse event: stroke volume

Adverse event: infusion

Adverse event: hypertension

Adverse event: dry mouth

Adverse event: hypotension
Study: 20932788

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 15316868

Adverse event: fractures

Adverse event: fractures

Adverse event: fractures

Adverse event: fractures

Adverse event: fractures

Adverse event: fractures
Study: 11736716

Adverse event: pain

Adverse event: pain
Study: 9522321

Adverse event: headache

Adverse event: migraine
Study: 7526126

Adverse event: fibronectin

Adverse event: fibronectin
Study: 3047394

Adverse event: drooling

Adverse event: drooling
Study: 29254669

Adverse event: pain

Adverse event: pain
Study: 28474075

Adverse event: fracture

Adverse event: fracture
Study: 21698591

Adverse event: surgery

Adverse event: surgery

Adverse event: surgery
Study: 9811282

Adverse event: stress
Study: 2700332

Adverse event: pain

Adverse event: pain
Study: 29246820

Adverse event: pain
Study: 28587974

Adverse event: chills
Study: 23172749

Adverse event: disease activity score
Study: 10899449

Adverse event: muscular dystrophy

Adverse event: duchenne muscular dystrophy
Study: 8834701

Adverse event: stress

Adverse event: stress

Adverse event: platelet count increased

Adverse event: platelet count
Study: 1563058

Adverse event: mean arterial pressure

Adverse event: mean arterial pressure
Study: 6609933

Adverse event: lymphopenia

Adverse event: lymphopenia
Study: 30098822

Adverse event: pain

Adverse event: pain

Adverse event: pain

Adverse event: disability

Adverse event: pain

Adverse event: disability
Study: 16968874

Adverse event: death
Study: 15882216

Adverse event: pain

Adverse event: pain

Adverse event: pain
Study: 11520478

Adverse event: agitation

Adverse event: agitation

Adverse event: agitation
Study: 9391998

Adverse event: hydroxyproline

Adverse event: hydroxyproline

Adverse event: hydroxyproline

Adverse event: osteocalcin

Adverse event: hydroxyproline

Adverse event: osteocalcin
Study: 3308571

Adverse event: wound

Adverse event: wound
Study: 24174910

Adverse event: injection
Study: 18344635

Adverse event: physical examination