Study: NCT02799069

Adverse event: Arrhythmia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 76 at risk

Adverse event: Gastritis
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 76 at risk

Adverse event: Respiratory tract infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 76 at risk

Adverse event: Myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 76 at risk

Adverse event: Application site irritation
Serious: no
Organ System: General disorders
Frequency: 25 affected / 76 at risk

Adverse event: Application site erythema
Serious: no
Organ System: General disorders
Frequency: 31 affected / 76 at risk

Adverse event: Application site oedema
Serious: no
Organ System: General disorders
Frequency: 1 affected / 76 at risk

Adverse event: Application site pain
Serious: no
Organ System: General disorders
Frequency: 19 affected / 76 at risk

Adverse event: Application site pruritus
Serious: no
Organ System: General disorders
Frequency: 6 affected / 76 at risk

Adverse event: Application site exfoliation
Serious: no
Organ System: General disorders
Frequency: 5 affected / 76 at risk

Adverse event: Application site scab
Serious: no
Organ System: General disorders
Frequency: 2 affected / 76 at risk

Adverse event: Application site vesicles
Serious: no
Organ System: General disorders
Frequency: 1 affected / 76 at risk

Adverse event: Application site paraesthesia
Serious: no
Organ System: General disorders
Frequency: 2 affected / 76 at risk

Adverse event: Skin exfoliation
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 76 at risk

Adverse event: Angina pectoris
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 248 at risk

Adverse event: Arrhythmia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 248 at risk

Adverse event: Contusion
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 248 at risk

Adverse event: Vascular graft occlusion
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 248 at risk

Adverse event: Malignant melanoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 248 at risk

Adverse event: Sarcoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 248 at risk

Adverse event: Epilepsy
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 248 at risk

Adverse event: Haemorrhagic stroke
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 248 at risk

Adverse event: Vertigo
Serious: yes
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 248 at risk

Adverse event: Glaucoma
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 248 at risk

Adverse event: Pleurisy
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 248 at risk

Adverse event: Peripheral artery stenosis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 248 at risk

Adverse event: Application site irritation
Serious: no
Organ System: General disorders
Frequency: 219 affected / 248 at risk

Adverse event: Application site erythema
Serious: no
Organ System: General disorders
Frequency: 198 affected / 248 at risk

Adverse event: Application site oedema
Serious: no
Organ System: General disorders
Frequency: 62 affected / 248 at risk

Adverse event: Application site pain
Serious: no
Organ System: General disorders
Frequency: 175 affected / 248 at risk

Adverse event: Application site pruritus
Serious: no
Organ System: General disorders
Frequency: 60 affected / 248 at risk

Adverse event: Application site exfoliation
Serious: no
Organ System: General disorders
Frequency: 44 affected / 248 at risk

Adverse event: Application site scab
Serious: no
Organ System: General disorders
Frequency: 27 affected / 248 at risk

Adverse event: Application site induration
Serious: no
Organ System: General disorders
Frequency: 24 affected / 248 at risk

Adverse event: Application site vesicles
Serious: no
Organ System: General disorders
Frequency: 22 affected / 248 at risk

Adverse event: Application site paraesthesia
Serious: no
Organ System: General disorders
Frequency: 17 affected / 248 at risk

Adverse event: Skin exfoliation
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 17 affected / 248 at risk

Adverse event: Bradycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 246 at risk

Adverse event: Cardiac failure
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 246 at risk

Adverse event: Contusion
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 246 at risk

Adverse event: Spinal fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 246 at risk

Adverse event: Chronic lymphocytic leukaemia
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 246 at risk

Adverse event: Non-Hodgkin's lymphoma stage II
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 246 at risk

Adverse event: Cerebrovascular accident
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 246 at risk

Adverse event: Giant cell arteritis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 246 at risk

Adverse event: Peripheral vein thrombosis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 246 at risk

Adverse event: Cholelithiasis
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 246 at risk

Adverse event: Appendicitis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 246 at risk

Adverse event: Diabetes mellitus
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 246 at risk

Adverse event: Application site irritation
Serious: no
Organ System: General disorders
Frequency: 222 affected / 246 at risk

Adverse event: Application site erythema
Serious: no
Organ System: General disorders
Frequency: 199 affected / 246 at risk

Adverse event: Application site oedema
Serious: no
Organ System: General disorders
Frequency: 61 affected / 246 at risk

Adverse event: Application site pain
Serious: no
Organ System: General disorders
Frequency: 179 affected / 246 at risk

Adverse event: Application site pruritus
Serious: no
Organ System: General disorders
Frequency: 60 affected / 246 at risk

Adverse event: Application site exfoliation
Serious: no
Organ System: General disorders
Frequency: 44 affected / 246 at risk

Adverse event: Application site scab
Serious: no
Organ System: General disorders
Frequency: 30 affected / 246 at risk

Adverse event: Application site induration
Serious: no
Organ System: General disorders
Frequency: 21 affected / 246 at risk

Adverse event: Application site vesicles
Serious: no
Organ System: General disorders
Frequency: 23 affected / 246 at risk

Adverse event: Application site paraesthesia
Serious: no
Organ System: General disorders
Frequency: 18 affected / 246 at risk

Adverse event: Skin exfoliation
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 15 affected / 246 at risk