TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04456686

Adverse event: Supraventricular tachycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 77 at risk

Adverse event: Nephrolithiasis
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 77 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 77 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 5 affected / 77 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 77 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 77 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 77 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 77 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 77 at risk

Adverse event: Benign prostatic hyperplasia
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 30 at risk

Adverse event: Erectile dysfunction
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 30 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 4 affected / 77 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 36 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 1 affected / 36 at risk

Adverse event: Peripheral swelling
Serious: no
Organ System: General disorders
Frequency: 2 affected / 36 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 36 at risk

Adverse event: Vulvovaginal mycotic infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 26 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 5 affected / 36 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 36 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 36 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 36 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 36 at risk
Study: NCT04456959

Adverse event: Lung
Serious: yes
Organ System: General disorders
Frequency: 2 affected / 28 at risk

Adverse event: Veno-occlusive Disease (VOD)/Sinusoidal Obstruction Syndrome (SOS)
Serious: no
Organ System: General disorders
Frequency: 2 affected / 28 at risk

Adverse event: Liver
Serious: no
Organ System: General disorders
Frequency: 1 affected / 28 at risk
Study: NCT04458103

Adverse event: Bleed
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 6 affected / 17 at risk

Adverse event: Neurological Event
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 17 at risk

Adverse event: Infection
Serious: yes
Organ System: Infections and infestations
Frequency: 7 affected / 17 at risk

Adverse event: Renal Dysfunction
Serious: no
Organ System: Renal and urinary disorders
Frequency: 5 affected / 17 at risk

Adverse event: Arrhythmia
Serious: no
Organ System: Cardiac disorders
Frequency: 5 affected / 17 at risk

Adverse event: Respiratory Dysfunction
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 5 affected / 17 at risk

Adverse event: Hepatic Dysfunction
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 17 at risk

Adverse event: Bleed
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 56 affected / 144 at risk

Adverse event: Neurological Event
Serious: yes
Organ System: Nervous system disorders
Frequency: 13 affected / 144 at risk

Adverse event: Infection
Serious: yes
Organ System: Infections and infestations
Frequency: 66 affected / 144 at risk

Adverse event: Renal Dysfunction
Serious: no
Organ System: Renal and urinary disorders
Frequency: 27 affected / 144 at risk

Adverse event: Arrhythmia
Serious: no
Organ System: Cardiac disorders
Frequency: 46 affected / 144 at risk

Adverse event: Respiratory Dysfunction
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 25 affected / 144 at risk
Study: NCT04458675

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 31 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 31 at risk

Adverse event: Other
Serious: no
Organ System: General disorders
Frequency: 2 affected / 31 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 28 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 28 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 28 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 28 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 28 at risk
Study: NCT04458818

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Upper respiratory tract infections
Frequency: 4 affected / 39 at risk

Adverse event: Skin infection
Serious: no
Organ System: Infections and infestations
Notes: Wound infection, post operatively
Frequency: 1 affected / 39 at risk
Study: NCT04458948

Adverse event: Clotting to vital organs (lungs, heart, kidney and brain)
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: All patients passed at one month. 9 passed during day 1 to 5 of the trial.
Frequency: 9 affected / 28 at risk
Study: NCT04459416

Adverse event: Contusion
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 26 affected / 151 at risk

Adverse event: Burning sensation
Serious: no
Organ System: General disorders
Frequency: 1 affected / 151 at risk

Adverse event: Skin discolouration
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 151 at risk

Adverse event: Foot cramping
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 151 at risk

Adverse event: Epistaxis
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 151 at risk

Adverse event: Pain/Soreness
Serious: no
Organ System: General disorders
Frequency: 7 affected / 151 at risk

Adverse event: Throbbing sensation
Serious: no
Organ System: General disorders
Frequency: 1 affected / 151 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 1 affected / 151 at risk
Study: NCT04459585

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 20 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 20 at risk

Adverse event: Paraesthesia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 20 at risk
Study: NCT04460027

Adverse event: Hospitalisation
Serious: yes
Organ System: General disorders
Notes: Hospitalization for alcohol detoxification
Frequency: 1 affected / 92 at risk
Study: NCT04460326

Adverse event: transfer to higher level of care
Serious: yes
Organ System: General disorders
Notes: After enrollment but before receiving any study medication pt became clinically worse and was transferred to a higher level of care. Subject was immediately discontinued from the study.
Frequency: 1 affected / 61 at risk

Adverse event: bleeding at CGM site
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: pt experienced bleeding at CGM site, sensor was removed and subject was discontinued from the study.
Frequency: 1 affected / 61 at risk
Study: NCT04460560

Adverse event: Hypotension
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 50 at risk

Adverse event: AKI
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 9 affected / 50 at risk

Adverse event: Thrombocytopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 50 at risk

Adverse event: Altered Mental Status (including hepatic encephalopathy)
Serious: yes
Organ System: Nervous system disorders
Frequency: 6 affected / 50 at risk

Adverse event: Electrolyte imbalance
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 2 affected / 50 at risk

Adverse event: Abdominal pain
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 50 at risk

Adverse event: Respiratory failure
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 50 at risk

Adverse event: Multiple organ dysfunction syndrome
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 50 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 50 at risk

Adverse event: Spontaneous bacterial peritonitis
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 50 at risk

Adverse event: Hepatic hydrothorax
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 50 at risk

Adverse event: Hepatic failure
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 3 affected / 50 at risk

Adverse event: Metastases to peritoneum
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 50 at risk

Adverse event: worsening ascites
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 5 affected / 50 at risk

Adverse event: Decompensated hepatic cirrhosis
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 50 at risk

Adverse event: Tachycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 50 at risk
Study: NCT04461015

Adverse event: Phlebitis
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 12 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 12 at risk

Adverse event: Phlebitis
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 12 at risk
Study: NCT04461483

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 6 at risk

Adverse event: Dry skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 6 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 6 at risk

Adverse event: Hiccups
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 6 at risk

Adverse event: Alopecia areata
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 6 at risk
Study: NCT04461795

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 40 at risk

Adverse event: Gastroenteritis
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 40 at risk

Adverse event: Injection site reaction
Serious: no
Organ System: General disorders
Frequency: 5 affected / 40 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 40 at risk

Adverse event: Neck pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 40 at risk
Study: NCT04463693

Adverse event: One week post-insertion site discomfort
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: 4 out 5 participants reported some insertion site discomfort one week after insertion of the etonogestrel implant. This is an anticipated adverse event
Frequency: 4 affected / 5 at risk

Adverse event: Persistent bothersome uterine bleeding
Serious: no
Organ System: Reproductive system and breast disorders
Notes: One participant reported persistent bothersome bleeding over the course of 12 months after etonogestrel implant insertion. This was an anticipated adverse event
Frequency: 1 affected / 5 at risk

Adverse event: Intermittent uterine bleeding
Serious: no
Organ System: Reproductive system and breast disorders
Notes: 3 out of 5 participants reported intermittent uterine bleeding over the course of 12 months after etonogestrel implant insertion. This was an anticipated adverse event
Frequency: 3 affected / 5 at risk
Study: NCT04464421

Adverse event: Overdose
Serious: yes
Organ System: Social circumstances
Frequency: 1 affected / 22 at risk

Adverse event: Incomplete spinal fusion
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 1 affected / 22 at risk
Study: NCT04464954

Adverse event: Adverse event
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: numbness/tingles
Frequency: 1 affected / 10 at risk

Adverse event: Adverse event
Serious: no
Organ System: Ear and labyrinth disorders
Notes: headache
Frequency: 1 affected / 10 at risk

Adverse event: Adverse event
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 10 at risk
Study: NCT04465162

Adverse event: Fatigue
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 13 affected / 73 at risk

Adverse event: Dermatitis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 24 affected / 73 at risk

Adverse event: Eye toxicities
Serious: no
Organ System: Eye disorders
Frequency: 13 affected / 73 at risk

Adverse event: Erythema
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 73 at risk

Adverse event: Retinopathy
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 73 at risk

Adverse event: Cataract
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 73 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 73 at risk

Adverse event: Ear
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 73 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 73 at risk

Adverse event: Skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 24 affected / 73 at risk

Adverse event: Larynx
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 5 affected / 73 at risk

Adverse event: Salivary
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 8 affected / 73 at risk

Adverse event: Mucosal inflammation
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 5 affected / 73 at risk

Adverse event: Pharynx
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 12 affected / 73 at risk

Adverse event: Upper GI
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 28 affected / 73 at risk

Adverse event: Lower GI
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 73 at risk

Adverse event: Genitourinary
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 73 at risk

Adverse event: Dehydration
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 73 at risk

Adverse event: Lung
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 73 at risk

Adverse event: Bone
Serious: no
Organ System: General disorders
Frequency: 1 affected / 73 at risk

Adverse event: Bladder
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 73 at risk
Study: NCT04465357

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 55 at risk
Study: NCT04465370

Adverse event: Admission For Atg Treatment For Rejection
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 89 at risk

Adverse event: Transplant Rejection Amr Grade 2
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 89 at risk

Adverse event: Cardiac
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 89 at risk

Adverse event: Other
Serious: yes
Organ System: Immune system disorders
Frequency: 2 affected / 89 at risk
Study: NCT04465630

Adverse event: Renal Failure (unrelated)
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 78 at risk

Adverse event: Coronary Artery Disease (unrelated)
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 78 at risk

Adverse event: COVID-19 (unrelated)
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: SARS COV-2 infection
Frequency: 1 affected / 78 at risk

Adverse event: Vitreous Hemorrhage (unrelated)
Serious: no
Organ System: Eye disorders
Notes: Intraoperative
Frequency: 1 affected / 78 at risk

Adverse event: Iris Prolapse (unrelated)
Serious: no
Organ System: Eye disorders
Notes: Intraoperative
Frequency: 1 affected / 78 at risk

Adverse event: Posterior Capsular Opacification (unrelated)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 78 at risk

Adverse event: Corneal edema after 1 week
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 78 at risk

Adverse event: Layered hyphema greater than or equal to 1mm (unrelated)
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 78 at risk

Adverse event: Clinically significant cystoid macular edema (unrelated)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 78 at risk

Adverse event: IOP increase of 10 mmHg above baseline IOP at 1 month or later
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 78 at risk

Adverse event: Benign paroxysmal positional vertigo (unrelated)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 78 at risk

Adverse event: Blepharitis (unrelated)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 78 at risk

Adverse event: Eye pain
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 78 at risk

Adverse event: Headache (unrelated)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 78 at risk

Adverse event: Headache above left eye (unrelated)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 78 at risk

Adverse event: Iris atrophy (unrelated)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 78 at risk

Adverse event: Iris prolapse (unrelated)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 78 at risk

Adverse event: Macular edema (unrelated)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 78 at risk

Adverse event: Small blood clots in trabecular meshwork (unrelated)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 78 at risk

Adverse event: Superficial punctate keratitis (unrelated)
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 78 at risk
Study: NCT04466111

Adverse event: Spinal cord bruising
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 58 at risk

Adverse event: Pocket Pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 58 at risk
Study: NCT04466384

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 10 at risk

Adverse event: COVID-19
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 10 at risk

Adverse event: Haematemesis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 14 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 14 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 14 at risk

Adverse event: Myalgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 14 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 14 at risk
Study: NCT04467697

Adverse event: Atrial fibrillation
Serious: yes
Organ System: Cardiac disorders
Notes: Event judged not treatment related by investigator.
Frequency: 1 affected / 155 at risk

Adverse event: Diverticular perforation
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Event judged not treatment related by investigator.
Frequency: 1 affected / 155 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 4 affected / 155 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 8 affected / 155 at risk

Adverse event: Viral upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 5 affected / 155 at risk

Adverse event: Influenza
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 155 at risk

Adverse event: Bronchitis
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 155 at risk

Adverse event: Haemoglobin increased
Serious: no
Organ System: Investigations
Notes: Event judged as treatment related by investigator.
Frequency: 3 affected / 155 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 155 at risk
Study: NCT04468204

Adverse event: Pain
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 39 at risk