Study: NCT01646385

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 205 affected / 3529 at risk

Adverse event: Sepsis
Serious: yes
Organ System: Infections and infestations
Frequency: 34 affected / 3529 at risk

Adverse event: Bone/Joint infection
Serious: yes
Organ System: Infections and infestations
Frequency: 83 affected / 3529 at risk

Adverse event: Other serious infection
Serious: yes
Organ System: Infections and infestations
Frequency: 314 affected / 3529 at risk

Adverse event: Lymphoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 11 affected / 3529 at risk

Adverse event: Plasma cell myeloma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 3529 at risk

Adverse event: Leukaemia
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 6 affected / 3529 at risk

Adverse event: Non-melanoma skin cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 79 affected / 3529 at risk

Adverse event: Solid tumours
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 153 affected / 3529 at risk

Adverse event: Cardiac failure congestive
Serious: yes
Organ System: Cardiac disorders
Frequency: 28 affected / 3529 at risk

Adverse event: Myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 65 affected / 3529 at risk

Adverse event: Other Cardiac events
Serious: yes
Organ System: Cardiac disorders
Frequency: 85 affected / 3529 at risk

Adverse event: Central demyelination
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 3529 at risk

Adverse event: Optic neuritis
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 3529 at risk

Adverse event: Neuropathy peripheral
Serious: yes
Organ System: Nervous system disorders
Frequency: 10 affected / 3529 at risk

Adverse event: Other CNS event
Serious: yes
Organ System: Nervous system disorders
Frequency: 117 affected / 3529 at risk

Adverse event: Aplastic anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 3529 at risk

Adverse event: Pancytopaenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 4 affected / 3529 at risk

Adverse event: Agranulocytosis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 3529 at risk

Adverse event: Other dyscrasia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 51 affected / 3529 at risk

Adverse event: Leukopaenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 7 affected / 3529 at risk

Adverse event: Pulmonary fibrosis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 14 affected / 3529 at risk

Adverse event: Death
Serious: yes
Organ System: General disorders
Frequency: 203 affected / 3529 at risk

Adverse event: Lymphoproliferative
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 18 affected / 3529 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 225 affected / 2864 at risk

Adverse event: Sepsis
Serious: yes
Organ System: Infections and infestations
Frequency: 28 affected / 2864 at risk

Adverse event: Bone/Joint infection
Serious: yes
Organ System: Infections and infestations
Frequency: 31 affected / 2864 at risk

Adverse event: Other serious infection
Serious: yes
Organ System: Infections and infestations
Frequency: 171 affected / 2864 at risk

Adverse event: Lymphoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 18 affected / 2864 at risk

Adverse event: Plasma cell myeloma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 4 affected / 2864 at risk

Adverse event: Leukaemia
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 7 affected / 2864 at risk

Adverse event: Non-melanoma skin cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 79 affected / 2864 at risk

Adverse event: Solid tumours
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 158 affected / 2864 at risk

Adverse event: Cardiac failure congestive
Serious: yes
Organ System: Cardiac disorders
Frequency: 36 affected / 2864 at risk

Adverse event: Myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 69 affected / 2864 at risk

Adverse event: Other Cardiac events
Serious: yes
Organ System: Cardiac disorders
Frequency: 102 affected / 2864 at risk

Adverse event: Central demyelination
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 2864 at risk

Adverse event: Neuropathy peripheral
Serious: yes
Organ System: Nervous system disorders
Frequency: 12 affected / 2864 at risk

Adverse event: Other CNS event
Serious: yes
Organ System: Nervous system disorders
Frequency: 85 affected / 2864 at risk

Adverse event: Pancytopaenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 8 affected / 2864 at risk

Adverse event: Other dyscrasia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 53 affected / 2864 at risk

Adverse event: Leukopaenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 2864 at risk

Adverse event: Pulmonary fibrosis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 13 affected / 2864 at risk

Adverse event: Death
Serious: yes
Organ System: General disorders
Frequency: 223 affected / 2864 at risk

Adverse event: Lymphoproliferative
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 29 affected / 2864 at risk