TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04350788

Adverse event: restarting cancer treatment
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Notes: After consent and enrollment, it was discovered that the patient started another round of radiation treatment during the study, making both the patient and his partner ineligible for our dyadic study. There is only one event.
Frequency: 1 affected / 62 at risk

Adverse event: Severe health problem
Serious: yes
Organ System: Cardiac disorders
Notes: The patient was hospitalized for about two months after having a stroke, and thus, made both the patient and his partner ineligible in the study. This is however only one event
Frequency: 1 affected / 62 at risk
Study: NCT04351087

Adverse event: Swelling
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 4 affected / 36 at risk

Adverse event: Pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 7 affected / 36 at risk

Adverse event: Swelling
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 35 at risk

Adverse event: Pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 7 affected / 35 at risk
Study: NCT04351269

Adverse event: Haematoma
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 165 at risk

Adverse event: Pocket Infection
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 165 at risk

Adverse event: Lead dislodgement
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 165 at risk

Adverse event: Superficial Surgical Site Infection
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 165 at risk

Adverse event: Thrombosis
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 165 at risk

Adverse event: Lead Perforation
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 165 at risk

Adverse event: Haematoma
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 219 at risk

Adverse event: Lead dislodgement
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 219 at risk

Adverse event: Superficial Surgical Site Infection
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 219 at risk

Adverse event: Lead Revision
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 219 at risk

Adverse event: Haemothorax
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 219 at risk

Adverse event: Lead dislodgement
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 71 at risk
Study: NCT04352101

Adverse event: Night sweats
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 10 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 10 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 1 affected / 10 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 1 affected / 10 at risk

Adverse event: Dry mouth
Serious: no
Organ System: General disorders
Frequency: 1 affected / 10 at risk

Adverse event: Chest pain
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 10 at risk

Adverse event: High blood pressure
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 10 at risk

Adverse event: Enlarged lymph nodes
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 10 at risk

Adverse event: Pain in extremity
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 10 at risk

Adverse event: Stress
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 10 at risk

Adverse event: Insomnia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 10 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 10 at risk

Adverse event: Abnormal dreams
Serious: no
Organ System: General disorders
Frequency: 1 affected / 10 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 10 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 1 affected / 8 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 8 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 8 at risk

Adverse event: Sleep disorder
Serious: no
Organ System: General disorders
Frequency: 1 affected / 8 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 2 affected / 8 at risk

Adverse event: Somnolence
Serious: no
Organ System: General disorders
Frequency: 1 affected / 8 at risk

Adverse event: Muscle tightness
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 8 at risk

Adverse event: Nightmare
Serious: no
Organ System: General disorders
Frequency: 1 affected / 8 at risk

Adverse event: Decreased libido
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 8 at risk
Study: NCT04352439

Adverse event: Deep vein thrombosis
Serious: yes
Organ System: Vascular disorders
Frequency: 4 affected / 19 at risk

Adverse event: Sepsis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 19 at risk

Adverse event: Thrombocytopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 19 at risk
Study: NCT04352660

Adverse event: Hypotony maculopathy
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 50 at risk

Adverse event: Choroidal effusions
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 50 at risk

Adverse event: Hypotony maculopathy
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 50 at risk

Adverse event: Choroidal effusions
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 50 at risk
Study: NCT04353037

Adverse event: Nasal congestion
Serious: no
Organ System: General disorders
Notes: Mild Nasal congestion
Frequency: 1 affected / 8 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Notes: Moderate Headache over a period of 6 days
Frequency: 1 affected / 8 at risk

Adverse event: Angioedema
Serious: no
Organ System: General disorders
Notes: Moderate Swelling of face (angioedema) over a period of 1 day.
Frequency: 1 affected / 8 at risk

Adverse event: Nausea
Serious: no
Organ System: General disorders
Notes: Moderate Nausea over a period of 6 days
Frequency: 1 affected / 8 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: General disorders
Notes: moderate decreased appetite over a period of 6 days
Frequency: 1 affected / 8 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: General disorders
Notes: moderate abdominal pain over a period of 6 days
Frequency: 1 affected / 8 at risk
Study: NCT04353284

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 35 at risk

Adverse event: Respiratory tract infection
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 35 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 35 at risk
Study: NCT04353596

Adverse event: Worsening of respiratory function
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 21 affected / 104 at risk

Adverse event: Urinary tract infection
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 104 at risk

Adverse event: Ventricular tachycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 104 at risk

Adverse event: Worsening of general condition
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 104 at risk

Adverse event: Worsening of respiratory function
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 5 affected / 104 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Renal and urinary disorders
Frequency: 2 affected / 104 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 104 at risk

Adverse event: Worsening of general condition
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 104 at risk

Adverse event: Worsening of respiratory function
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 24 affected / 100 at risk

Adverse event: Ischemic events
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 100 at risk

Adverse event: Worsening of general condition
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 100 at risk

Adverse event: Worsening of respiratory function
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 100 at risk

Adverse event: Elevation of creatinine
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 100 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 100 at risk

Adverse event: Worsening of general condition
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 100 at risk
Study: NCT04354428

Adverse event: Pneumonia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 83 at risk

Adverse event: Chest pain
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 83 at risk

Adverse event: Event leading to treatment discontinuation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 83 at risk

Adverse event: Chest pain
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 71 at risk

Adverse event: Pericarditis
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 71 at risk

Adverse event: Event leading to treatment discontinuation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 71 at risk

Adverse event: QT Prolongation
Serious: no
Organ System: Cardiac disorders
Frequency: 2 affected / 71 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 71 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 77 at risk

Adverse event: Enterocolitis haemorrhagic
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 77 at risk

Adverse event: Event leading to treatment discontinuation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 77 at risk

Adverse event: Drug Reaction
Serious: no
Organ System: Immune system disorders
Notes: Reaction or Hives
Frequency: 2 affected / 77 at risk

Adverse event: Event leading to treatment discontinuation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 9 affected / 29 at risk

Adverse event: Pulmonary embolism
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 29 at risk
Study: NCT04354831

Adverse event: Bacteraemia
Serious: yes
Organ System: Infections and infestations
Notes: Patients who developed bacteremia during the hospital stay after enrollment and plasma infusion (not directly related to plasma infusion)
Frequency: 4 affected / 41 at risk

Adverse event: Endotracheal intubation
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Required intubation after enrollment and plasma infusion during the hospital stay (not directly related to plasma infusion)
Frequency: 11 affected / 41 at risk

Adverse event: Bacteraemia
Serious: yes
Organ System: Infections and infestations
Notes: Patients who developed bacteremia during the hospital stay after enrollment and plasma infusion (not directly related to plasma infusion)
Frequency: 1 affected / 89 at risk

Adverse event: ICU Transfer
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Patients requiring ICU transfer after enrollment and plasma infusion (not directly related to plasma infustion)
Frequency: 14 affected / 89 at risk

Adverse event: Endotracheal intubation
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Required intubation after enrollment and plasma infusion during the hospital stay (not directly related to plasma infusion)
Frequency: 7 affected / 89 at risk

Adverse event: Dialysis
Serious: yes
Organ System: Renal and urinary disorders
Notes: Developed renal failure after enrollment and plasma infusion during hospitalization requiring dialysis (not related to plasma infusion)
Frequency: 1 affected / 89 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Notes: Fever developed during infusion of convalescent plasma
Frequency: 2 affected / 89 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Rash developed within 72 hours of plasma infusion
Frequency: 2 affected / 89 at risk
Study: NCT04354870

Adverse event: Tinnitus
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 83 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 83 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 83 at risk

Adverse event: Alopecia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 83 at risk

Adverse event: Appetite Loss
Serious: no
Organ System: General disorders
Frequency: 1 affected / 83 at risk

Adverse event: Abdominal discomfort
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 83 at risk

Adverse event: Gastrooesophageal reflux disease
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 83 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 83 at risk
Study: NCT04355143

Adverse event: GI discomfort
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 48 at risk
Study: NCT04355663

Adverse event: Fall
Serious: yes
Organ System: Nervous system disorders
Notes: an increased number of falls
Frequency: 1 affected / 21 at risk
Study: NCT04356027

Adverse event: Vascular dissection
Serious: yes
Organ System: Vascular disorders
Frequency: 2 affected / 312 at risk

Adverse event: Hypotension
Serious: yes
Organ System: Vascular disorders
Frequency: 2 affected / 312 at risk

Adverse event: Vessel perforation
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 312 at risk

Adverse event: Angina pectoris
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 312 at risk

Adverse event: Atrial fibrillation
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 312 at risk

Adverse event: Pericardial effusion
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 312 at risk

Adverse event: Vascular dissection
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 312 at risk
Study: NCT04356573

Adverse event: Viral Bronchitis
Serious: no
Organ System: Infections and infestations
Notes: Event unrelated to study treatments/arms.

Subject told staff she was diagnosed with viral bronchitis on Oct. 24th. Treated with abx on 11/9/18. Nearly resolved as of 11/20/18.
Frequency: 1 affected / 12 at risk
Study: NCT04356690

Adverse event: Febrile neutropenia
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 6 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Thrombocytopenia
Frequency: 2 affected / 6 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: anemia
Frequency: 4 affected / 6 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: neutropenia
Frequency: 3 affected / 6 at risk

Adverse event: Liver function test abnormal
Serious: no
Organ System: Hepatobiliary disorders
Notes: Abnormal LFTs
Frequency: 1 affected / 6 at risk

Adverse event: acute kidney innury
Serious: no
Organ System: Renal and urinary disorders
Notes: acute kidney injury
Frequency: 1 affected / 6 at risk

Adverse event: ventilatory asscociated pneumonia
Serious: no
Organ System: Infections and infestations
Notes: ventilator associated pneumonia (non-neutropenic)
Frequency: 1 affected / 6 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: anemia
Frequency: 1 affected / 2 at risk

Adverse event: acute kidney innury
Serious: no
Organ System: Renal and urinary disorders
Notes: acute kidney injury
Frequency: 1 affected / 2 at risk
Study: NCT04357379

Adverse event: Cough
Serious: no
Organ System: General disorders
Frequency: 1 affected / 10 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 1 affected / 10 at risk

Adverse event: Nausea
Serious: no
Organ System: General disorders
Frequency: 1 affected / 10 at risk

Adverse event: ER visit for medication refill
Serious: no
Organ System: General disorders
Frequency: 1 affected / 10 at risk
Study: NCT04357782

Adverse event: Nausea, self-limited
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 10 at risk

Adverse event: Dry mouth
Serious: no
Organ System: General disorders
Frequency: 2 affected / 10 at risk

Adverse event: Chest pain
Serious: no
Organ System: General disorders
Notes: Mild, self limited
Frequency: 1 affected / 10 at risk

Adverse event: Atrial fibrillation
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 10 at risk

Adverse event: Acute respiratory failure
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Mechanical intubation due to worsening acute hypoxemic respiratory failure due to COVID-19.
Frequency: 2 affected / 10 at risk

Adverse event: Acute kidney injury
Serious: yes
Organ System: Renal and urinary disorders
Notes: Acute kidney injury, stage 3 due to ischemia
Frequency: 2 affected / 10 at risk

Adverse event: Pulseless Electrical Activity Arrest
Serious: yes
Organ System: Cardiac disorders
Notes: Pulse-less electrical activity arrest from acute hypoxemic respiratory failure due to COVID-19, day 2
Frequency: 2 affected / 10 at risk

Adverse event: Ischaemic hepatitis
Serious: yes
Organ System: Hepatobiliary disorders
Notes: Hepatic Failure/ischemic hepatitis post pulseless electrical activity arrest
Frequency: 1 affected / 10 at risk

Adverse event: Elevated ALT
Serious: no
Organ System: Hepatobiliary disorders
Notes: Elevated ALT/DILI with peak ALT of 423 IU/L, likely due to tocilizumab
Frequency: 1 affected / 10 at risk

Adverse event: Embolism
Serious: no
Organ System: Vascular disorders
Notes: Deep vein thrombosis left posterior tibial
Frequency: 1 affected / 10 at risk

Adverse event: Pneumonia
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: +methicillin-resistant Staphylococcus aureus (MRSA) sputum culture
Frequency: 1 affected / 10 at risk

Adverse event: Bacteraemia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: coagulase-negative
Frequency: 2 affected / 10 at risk

Adverse event: Chest pain
Serious: no
Organ System: General disorders
Notes: Mild, self limited
Frequency: 2 affected / 10 at risk

Adverse event: Elevated ALT
Serious: no
Organ System: Hepatobiliary disorders
Notes: likely related to remdesivir, resolved
Frequency: 1 affected / 10 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Notes: \< 4 episodes per day
Frequency: 1 affected / 10 at risk

Adverse event: Atrial fibrillation
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 10 at risk
Study: NCT04357795

Adverse event: Instillation site irritation
Serious: no
Organ System: General disorders
Frequency: 17 affected / 134 at risk

Adverse event: Instillation site pain
Serious: no
Organ System: General disorders
Frequency: 3 affected / 134 at risk
Study: NCT04357964

Adverse event: Local skin reaction
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Redness, bruising or tenderness around biopsy site.
Frequency: 4 affected / 55 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Notes: Experience nausea during the biopsy procedure.
Frequency: 2 affected / 55 at risk

Adverse event: Lightheaded
Serious: no
Organ System: Vascular disorders
Notes: Experienced lightheadedness during biopsy procedure.
Frequency: 3 affected / 55 at risk
Study: NCT04358068

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 9 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 9 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 9 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 9 at risk

Adverse event: Ageusia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 9 at risk

Adverse event: Anosmia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 9 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 9 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 9 at risk

Adverse event: COVID-19
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 11 at risk

Adverse event: Tinnitus
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 11 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 11 at risk

Adverse event: Ageusia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 11 at risk

Adverse event: Anosmia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 11 at risk

Adverse event: Confusional state
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 11 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 11 at risk

Adverse event: Nasal obstruction
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 11 at risk