Study: NCT04079517

Adverse event: Numbness/tingling in the hands and feet
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 23 at risk

Adverse event: Mood swings
Serious: no
Organ System: Nervous system disorders
Frequency: 6 affected / 23 at risk

Adverse event: Headaches
Serious: no
Organ System: Nervous system disorders
Frequency: 10 affected / 23 at risk

Adverse event: Disturbance in attention
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 23 at risk

Adverse event: Depressed mood
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 23 at risk

Adverse event: Irritability
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 23 at risk

Adverse event: Lack of energy
Serious: no
Organ System: Nervous system disorders
Frequency: 6 affected / 23 at risk

Adverse event: Anxiety
Serious: no
Organ System: Nervous system disorders
Frequency: 7 affected / 23 at risk

Adverse event: Eyesight changes
Serious: no
Organ System: Nervous system disorders
Frequency: 6 affected / 23 at risk

Adverse event: Insomnia
Serious: no
Organ System: Nervous system disorders
Frequency: 11 affected / 23 at risk

Adverse event: Feel lightheaded (dizzy)
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 23 at risk

Adverse event: Vaginal discharge
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 7 affected / 23 at risk

Adverse event: Libido decreased
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 9 affected / 23 at risk

Adverse event: Vaginal itching/irritation
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 3 affected / 23 at risk

Adverse event: Pain from breast tissue or breast skin
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 4 affected / 23 at risk

Adverse event: Fragile mucous membranes/ Mucous membrane disorder
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 7 affected / 23 at risk

Adverse event: Dyspareunia
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 4 affected / 23 at risk

Adverse event: Vulvovaginal dryness
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 11 affected / 23 at risk

Adverse event: skin rashes
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 6 affected / 23 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 7 affected / 23 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 23 at risk

Adverse event: Problems with urination
Serious: no
Organ System: Renal and urinary disorders
Frequency: 2 affected / 23 at risk

Adverse event: Cold sweat
Serious: no
Organ System: Endocrine disorders
Frequency: 8 affected / 23 at risk

Adverse event: Night sweats
Serious: no
Organ System: Endocrine disorders
Frequency: 15 affected / 23 at risk

Adverse event: Menopausal symptoms
Serious: no
Organ System: Endocrine disorders
Frequency: 14 affected / 23 at risk

Adverse event: muscle cramps (e.g. in legs)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 14 affected / 23 at risk

Adverse event: Pain in joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 12 affected / 23 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 6 affected / 23 at risk

Adverse event: Constipation
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 23 at risk

Adverse event: Weight increased
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 12 affected / 23 at risk

Adverse event: Nausea
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 7 affected / 23 at risk

Adverse event: Vomiting
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 12 affected / 23 at risk

Adverse event: Numbness/tingling in the hands and feet
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 19 at risk

Adverse event: Mood swings
Serious: no
Organ System: Nervous system disorders
Frequency: 6 affected / 19 at risk

Adverse event: Headaches
Serious: no
Organ System: Nervous system disorders
Frequency: 9 affected / 19 at risk

Adverse event: Disturbance in attention
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 19 at risk

Adverse event: Depressed mood
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 19 at risk

Adverse event: Irritability
Serious: no
Organ System: Nervous system disorders
Frequency: 7 affected / 19 at risk

Adverse event: Lack of energy
Serious: no
Organ System: Nervous system disorders
Frequency: 7 affected / 19 at risk

Adverse event: Anxiety
Serious: no
Organ System: Nervous system disorders
Frequency: 6 affected / 19 at risk

Adverse event: Eyesight changes
Serious: no
Organ System: Nervous system disorders
Frequency: 8 affected / 19 at risk

Adverse event: Insomnia
Serious: no
Organ System: Nervous system disorders
Frequency: 9 affected / 19 at risk

Adverse event: Feel lightheaded (dizzy)
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 19 at risk

Adverse event: Vaginal bleeding or spotting
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 2 affected / 19 at risk

Adverse event: Vaginal discharge
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 11 affected / 19 at risk

Adverse event: Libido decreased
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 10 affected / 19 at risk

Adverse event: Vaginal itching/irritation
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 5 affected / 19 at risk

Adverse event: Pain from breast tissue or breast skin
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 5 affected / 19 at risk

Adverse event: Fragile mucous membranes/ Mucous membrane disorder
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 10 affected / 19 at risk

Adverse event: Dyspareunia
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 5 affected / 19 at risk

Adverse event: Vulvovaginal dryness
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 14 affected / 19 at risk

Adverse event: skin rashes
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 4 affected / 19 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 7 affected / 19 at risk

Adverse event: Problems with urination
Serious: no
Organ System: Renal and urinary disorders
Frequency: 3 affected / 19 at risk

Adverse event: Cold sweat
Serious: no
Organ System: Endocrine disorders
Frequency: 9 affected / 19 at risk

Adverse event: Night sweats
Serious: no
Organ System: Endocrine disorders
Frequency: 18 affected / 19 at risk

Adverse event: Menopausal symptoms
Serious: no
Organ System: Endocrine disorders
Frequency: 17 affected / 19 at risk

Adverse event: muscle cramps (e.g. in legs)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 16 affected / 19 at risk

Adverse event: Pain in joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 11 affected / 19 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 3 affected / 19 at risk

Adverse event: Constipation
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 5 affected / 19 at risk

Adverse event: Weight increased
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 14 affected / 19 at risk

Adverse event: Nausea
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 6 affected / 19 at risk

Adverse event: Vomiting
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 13 affected / 19 at risk