Study: NCT04005352

Adverse event: Iron deficiency anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 366 at risk

Adverse event: Acute myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 366 at risk

Adverse event: Angina pectoris
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 366 at risk

Adverse event: Atrial fibrillation
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 366 at risk

Adverse event: Atrial flutter
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 366 at risk

Adverse event: Cardiac arrest
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 366 at risk

Adverse event: Cardiac failure
Serious: yes
Organ System: Cardiac disorders
Frequency: 3 affected / 366 at risk

Adverse event: Cardiac failure congestive
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 366 at risk

Adverse event: Coronary artery stenosis
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 366 at risk

Adverse event: Myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 366 at risk

Adverse event: Sinus node dysfunction
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 366 at risk

Adverse event: Tachycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 366 at risk

Adverse event: Vertigo positional
Serious: yes
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 366 at risk

Adverse event: Eye inflammation - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 366 at risk

Adverse event: Iridocyclitis - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 366 at risk

Adverse event: Macular hole - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 366 at risk

Adverse event: Ocular discomfort - Fellow Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 366 at risk

Adverse event: Ocular discomfort - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 366 at risk

Adverse event: Retinal artery occlusion - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 366 at risk

Adverse event: Retinal vascular occlusion - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 366 at risk

Adverse event: Uveitis - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 3 affected / 366 at risk

Adverse event: Visual acuity reduced - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 366 at risk

Adverse event: Gingival bleeding
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 366 at risk

Adverse event: Inguinal hernia
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 366 at risk

Adverse event: Cholecystitis
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 366 at risk

Adverse event: Anaphylactic shock
Serious: yes
Organ System: Immune system disorders
Frequency: 1 affected / 366 at risk

Adverse event: COVID-19
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 366 at risk

Adverse event: COVID-19 pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 5 affected / 366 at risk

Adverse event: Endophthalmitis - Study Eye
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 366 at risk

Adverse event: Erysipelas
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 366 at risk

Adverse event: Herpes zoster
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 366 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 366 at risk

Adverse event: Cervical vertebral fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 366 at risk

Adverse event: Craniocerebral injury
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 366 at risk

Adverse event: Femoral neck fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 366 at risk

Adverse event: Foot fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 366 at risk

Adverse event: Forearm fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 366 at risk

Adverse event: Hip fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 366 at risk

Adverse event: Incisional hernia
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 366 at risk

Adverse event: Radius fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 366 at risk

Adverse event: Thoracic vertebral fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 366 at risk

Adverse event: Wrist fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 366 at risk

Adverse event: Cachexia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 366 at risk

Adverse event: Hyperkalaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 366 at risk

Adverse event: Neck pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 366 at risk

Adverse event: Osteoarthritis
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 366 at risk

Adverse event: Spinal stenosis
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 366 at risk

Adverse event: Adenocarcinoma gastric
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 366 at risk

Adverse event: Breast cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 366 at risk

Adverse event: Colon cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 366 at risk

Adverse event: Hepatic cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 366 at risk

Adverse event: Lung neoplasm
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 366 at risk

Adverse event: Metastatic squamous cell carcinoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 366 at risk

Adverse event: Non-small cell lung cancer metastatic
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 366 at risk

Adverse event: Tongue neoplasm malignant stage unspecified
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 366 at risk

Adverse event: Basal ganglia infarction
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 366 at risk

Adverse event: Carotid artery stenosis
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 366 at risk

Adverse event: Transient ischaemic attack
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 366 at risk

Adverse event: Nephrolithiasis
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 366 at risk

Adverse event: Dyspnoea exertional
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 366 at risk

Adverse event: Epistaxis
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 366 at risk

Adverse event: Hypercapnia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 366 at risk

Adverse event: Pneumonitis
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 366 at risk

Adverse event: Aortic stenosis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 366 at risk

Adverse event: Atrial fibrillation
Serious: no
Organ System: Cardiac disorders
Frequency: 6 affected / 366 at risk

Adverse event: Vertigo
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 4 affected / 366 at risk

Adverse event: Cataract - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 366 at risk

Adverse event: Choroidal neovascularisation - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 366 at risk

Adverse event: Conjunctival haemorrhage - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 366 at risk

Adverse event: Conjunctival haemorrhage - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 23 affected / 366 at risk

Adverse event: Dry eye - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 366 at risk

Adverse event: Dry eye - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 8 affected / 366 at risk

Adverse event: Eye pain - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 366 at risk

Adverse event: Eye pain - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 17 affected / 366 at risk

Adverse event: Eye pruritus - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 366 at risk

Adverse event: Foreign body sensation in eyes - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 366 at risk

Adverse event: Lacrimation increased - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 366 at risk

Adverse event: Macular oedema - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 366 at risk

Adverse event: Neovascular age-related macular degeneration - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 22 affected / 366 at risk

Adverse event: Neovascular age-related macular degeneration - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 366 at risk

Adverse event: Posterior capsule opacification - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 366 at risk

Adverse event: Retinal depigmentation - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 366 at risk

Adverse event: Retinal haemorrhage - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 366 at risk

Adverse event: Retinal oedema - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 366 at risk

Adverse event: Retinal pigment epithelial tear - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 366 at risk

Adverse event: Subretinal fibrosis - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 366 at risk

Adverse event: Subretinal fluid - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 366 at risk

Adverse event: Vision blurred - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 366 at risk

Adverse event: Visual acuity reduced - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 366 at risk

Adverse event: Visual acuity reduced - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 18 affected / 366 at risk

Adverse event: Vitreous detachment - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 366 at risk

Adverse event: Vitreous detachment - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 11 affected / 366 at risk

Adverse event: Vitreous floaters - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 14 affected / 366 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 366 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 366 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 366 at risk

Adverse event: COVID-19
Serious: no
Organ System: Infections and infestations
Frequency: 9 affected / 366 at risk

Adverse event: Conjunctivitis - Fellow Eye
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 366 at risk

Adverse event: Conjunctivitis - Study Eye
Serious: no
Organ System: Infections and infestations
Frequency: 5 affected / 366 at risk

Adverse event: Cystitis
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 366 at risk

Adverse event: Hordeolum - Study Eye
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 366 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 12 affected / 366 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 11 affected / 366 at risk

Adverse event: Fall
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 6 affected / 366 at risk

Adverse event: Intra-ocular injection complication - Study Eye
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 6 affected / 366 at risk

Adverse event: Vaccination complication
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 3 affected / 366 at risk

Adverse event: Gamma-glutamyltransferase increased
Serious: no
Organ System: Investigations
Frequency: 4 affected / 366 at risk

Adverse event: Intraocular pressure increased - Study Eye
Serious: no
Organ System: Investigations
Frequency: 5 affected / 366 at risk

Adverse event: Diabetes mellitus
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 366 at risk

Adverse event: Hypercholesterolaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 366 at risk

Adverse event: Hyperuricaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 366 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 8 affected / 366 at risk

Adverse event: Osteoarthritis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 6 affected / 366 at risk

Adverse event: Carpal tunnel syndrome
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 366 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 366 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 10 affected / 366 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 5 affected / 366 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 366 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 18 affected / 366 at risk

Adverse event: Acute myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 368 at risk

Adverse event: Arrhythmia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 368 at risk

Adverse event: Cardiac failure
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 368 at risk

Adverse event: Coronary artery disease
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 368 at risk

Adverse event: Myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 368 at risk

Adverse event: Myocardial ischaemia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 368 at risk

Adverse event: Glaucoma - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 368 at risk

Adverse event: Iridocyclitis - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 368 at risk

Adverse event: Retinal vein occlusion - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 368 at risk

Adverse event: Abdominal adhesions
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 368 at risk

Adverse event: Ileus paralytic
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 368 at risk

Adverse event: Chest discomfort
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 368 at risk

Adverse event: COVID-19 pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 368 at risk

Adverse event: Diverticulitis
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 368 at risk

Adverse event: Escherichia sepsis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 368 at risk

Adverse event: Pneumonia viral
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 368 at risk

Adverse event: Pyelonephritis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 368 at risk

Adverse event: Urosepsis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 368 at risk

Adverse event: Cervical vertebral fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 368 at risk

Adverse event: Concussion
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 368 at risk

Adverse event: Face injury
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 368 at risk

Adverse event: Craniofacial fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 368 at risk

Adverse event: Fall
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 368 at risk

Adverse event: Femoral neck fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 368 at risk

Adverse event: Femur fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 368 at risk

Adverse event: Hip fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 368 at risk

Adverse event: Meniscus injury
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 368 at risk

Adverse event: Radius fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 368 at risk

Adverse event: Stress fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 368 at risk

Adverse event: Intraocular pressure increased - Study Eye
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 368 at risk

Adverse event: Hyponatraemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 368 at risk

Adverse event: Neck pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 368 at risk

Adverse event: Osteoarthritis
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 368 at risk

Adverse event: Spondylolisthesis
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 368 at risk

Adverse event: Anal cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 368 at risk

Adverse event: Breast cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 368 at risk

Adverse event: Colon cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 2 affected / 368 at risk

Adverse event: Lung neoplasm
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 368 at risk

Adverse event: Neoplasm
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 368 at risk

Adverse event: Pancreatic carcinoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 368 at risk

Adverse event: Renal neoplasm
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 368 at risk

Adverse event: Squamous cell carcinoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 368 at risk

Adverse event: Cerebral infarction
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 368 at risk

Adverse event: Cerebrovascular accident
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 368 at risk

Adverse event: Dizziness
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 368 at risk

Adverse event: Speech disorder
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 368 at risk

Adverse event: Abnormal behaviour
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 368 at risk

Adverse event: Psychotic disorder due to a general medical condition
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 368 at risk

Adverse event: Acute kidney injury
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 368 at risk

Adverse event: Haematuria
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 368 at risk

Adverse event: Ureterolithiasis
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 368 at risk

Adverse event: Acute respiratory failure
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 368 at risk

Adverse event: Pulmonary embolism
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 368 at risk

Adverse event: Pulmonary oedema
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 368 at risk

Adverse event: Aortic stenosis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 368 at risk

Adverse event: Deep vein thrombosis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 368 at risk

Adverse event: Hypertensive crisis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 368 at risk

Adverse event: Peripheral arterial occlusive disease
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 368 at risk

Adverse event: Peripheral artery aneurysm rupture
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 368 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 4 affected / 368 at risk

Adverse event: Atrial fibrillation
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 368 at risk

Adverse event: Vertigo
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 4 affected / 368 at risk

Adverse event: Cataract - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 368 at risk

Adverse event: Choroidal neovascularisation - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 368 at risk

Adverse event: Conjunctival haemorrhage - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 368 at risk

Adverse event: Conjunctival haemorrhage - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 13 affected / 368 at risk

Adverse event: Detachment of retinal pigment epithelium - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 368 at risk

Adverse event: Dry eye - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 16 affected / 368 at risk

Adverse event: Dry eye - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 18 affected / 368 at risk

Adverse event: Eye pain - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 368 at risk

Adverse event: Eye pain - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 13 affected / 368 at risk

Adverse event: Eye pruritus - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 368 at risk

Adverse event: Foreign body sensation in eyes - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 8 affected / 368 at risk

Adverse event: Lacrimation increased - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 368 at risk

Adverse event: Macular oedema - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 368 at risk

Adverse event: Neovascular age-related macular degeneration - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 17 affected / 368 at risk

Adverse event: Neovascular age-related macular degeneration - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 368 at risk

Adverse event: Posterior capsule opacification - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 368 at risk

Adverse event: Retinal depigmentation - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 368 at risk

Adverse event: Retinal haemorrhage - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 368 at risk

Adverse event: Retinal oedema - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 368 at risk

Adverse event: Retinal pigment epithelial tear - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 368 at risk

Adverse event: Subretinal fluid - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 11 affected / 368 at risk

Adverse event: Vision blurred - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 368 at risk

Adverse event: Visual acuity reduced - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 368 at risk

Adverse event: Visual acuity reduced - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 19 affected / 368 at risk

Adverse event: Vitreous detachment - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 368 at risk

Adverse event: Vitreous detachment - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 368 at risk

Adverse event: Vitreous floaters - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 368 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 368 at risk

Adverse event: COVID-19
Serious: no
Organ System: Infections and infestations
Frequency: 16 affected / 368 at risk

Adverse event: Conjunctivitis - Fellow Eye
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 368 at risk

Adverse event: Conjunctivitis - Study Eye
Serious: no
Organ System: Infections and infestations
Frequency: 5 affected / 368 at risk

Adverse event: Cystitis
Serious: no
Organ System: Infections and infestations
Frequency: 5 affected / 368 at risk

Adverse event: Hordeolum - Study Eye
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 368 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 11 affected / 368 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 10 affected / 368 at risk

Adverse event: Fall
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 9 affected / 368 at risk

Adverse event: Intra-ocular injection complication - Study Eye
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 3 affected / 368 at risk

Adverse event: Vaccination complication
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 4 affected / 368 at risk

Adverse event: Gamma-glutamyltransferase increased
Serious: no
Organ System: Investigations
Frequency: 3 affected / 368 at risk

Adverse event: Intraocular pressure increased - Study Eye
Serious: no
Organ System: Investigations
Frequency: 10 affected / 368 at risk

Adverse event: Diabetes mellitus
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 368 at risk

Adverse event: Hypercholesterolaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 6 affected / 368 at risk

Adverse event: Hyperuricaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 368 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 8 affected / 368 at risk

Adverse event: Osteoarthritis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 368 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 368 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 11 affected / 368 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 368 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 17 affected / 368 at risk

Adverse event: Iron deficiency anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 734 at risk

Adverse event: Acute myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 3 affected / 734 at risk

Adverse event: Angina pectoris
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 734 at risk

Adverse event: Arrhythmia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 734 at risk

Adverse event: Atrial fibrillation
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 734 at risk

Adverse event: Atrial flutter
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 734 at risk

Adverse event: Cardiac arrest
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 734 at risk

Adverse event: Cardiac failure
Serious: yes
Organ System: Cardiac disorders
Frequency: 4 affected / 734 at risk

Adverse event: Cardiac failure congestive
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 734 at risk

Adverse event: Coronary artery disease
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 734 at risk

Adverse event: Coronary artery stenosis
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 734 at risk

Adverse event: Myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 3 affected / 734 at risk

Adverse event: Myocardial ischaemia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 734 at risk

Adverse event: Sinus node dysfunction
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 734 at risk

Adverse event: Tachycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 734 at risk

Adverse event: Vertigo positional
Serious: yes
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 734 at risk

Adverse event: Eye inflammation - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 734 at risk

Adverse event: Glaucoma - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 734 at risk

Adverse event: Iridocyclitis - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 2 affected / 734 at risk

Adverse event: Macular hole - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 734 at risk

Adverse event: Ocular discomfort - Fellow Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 734 at risk

Adverse event: Ocular discomfort - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 734 at risk

Adverse event: Retinal artery occlusion - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 734 at risk

Adverse event: Retinal vascular occlusion - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 734 at risk

Adverse event: Retinal vein occlusion - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 734 at risk

Adverse event: Uveitis - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 3 affected / 734 at risk

Adverse event: Visual acuity reduced - Study Eye
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 734 at risk

Adverse event: Abdominal adhesions
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 734 at risk

Adverse event: Gingival bleeding
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 734 at risk

Adverse event: Ileus paralytic
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 734 at risk

Adverse event: Inguinal hernia
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 734 at risk

Adverse event: Chest discomfort
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 734 at risk

Adverse event: Cholecystitis
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 734 at risk

Adverse event: Anaphylactic shock
Serious: yes
Organ System: Immune system disorders
Frequency: 1 affected / 734 at risk

Adverse event: COVID-19
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 734 at risk

Adverse event: COVID-19 pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 6 affected / 734 at risk

Adverse event: Diverticulitis
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 734 at risk

Adverse event: Endophthalmitis - Study Eye
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 734 at risk

Adverse event: Erysipelas
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 734 at risk

Adverse event: Escherichia sepsis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 734 at risk

Adverse event: Herpes zoster
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 734 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 734 at risk

Adverse event: Pneumonia viral
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 734 at risk

Adverse event: Pyelonephritis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 734 at risk

Adverse event: Urosepsis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 734 at risk

Adverse event: Cervical vertebral fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 734 at risk

Adverse event: Concussion
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 734 at risk

Adverse event: Craniocerebral injury
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 734 at risk

Adverse event: Face injury
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 734 at risk

Adverse event: Craniofacial fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 734 at risk

Adverse event: Fall
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 734 at risk

Adverse event: Femoral neck fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 3 affected / 734 at risk

Adverse event: Femur fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 734 at risk

Adverse event: Foot fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 734 at risk

Adverse event: Forearm fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 734 at risk

Adverse event: Hip fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 734 at risk

Adverse event: Incisional hernia
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 734 at risk

Adverse event: Meniscus injury
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 734 at risk

Adverse event: Radius fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 734 at risk

Adverse event: Stress fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 734 at risk

Adverse event: Thoracic vertebral fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 734 at risk

Adverse event: Wrist fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 734 at risk

Adverse event: Intraocular pressure increased - Study Eye
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 734 at risk

Adverse event: Cachexia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 734 at risk

Adverse event: Hyperkalaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 734 at risk

Adverse event: Hyponatraemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 734 at risk

Adverse event: Neck pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 734 at risk

Adverse event: Osteoarthritis
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 734 at risk

Adverse event: Spinal stenosis
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 734 at risk

Adverse event: Spondylolisthesis
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 734 at risk

Adverse event: Adenocarcinoma gastric
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 734 at risk

Adverse event: Anal cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 734 at risk

Adverse event: Breast cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 2 affected / 734 at risk

Adverse event: Colon cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 3 affected / 734 at risk

Adverse event: Hepatic cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 734 at risk

Adverse event: Lung neoplasm
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 2 affected / 734 at risk

Adverse event: Metastatic squamous cell carcinoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 734 at risk

Adverse event: Neoplasm
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 734 at risk

Adverse event: Non-small cell lung cancer metastatic
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 734 at risk

Adverse event: Pancreatic carcinoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 734 at risk

Adverse event: Renal neoplasm
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 734 at risk

Adverse event: Squamous cell carcinoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 734 at risk

Adverse event: Tongue neoplasm malignant stage unspecified
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 734 at risk

Adverse event: Basal ganglia infarction
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 734 at risk

Adverse event: Carotid artery stenosis
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 734 at risk

Adverse event: Cerebral infarction
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 734 at risk

Adverse event: Cerebrovascular accident
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 734 at risk

Adverse event: Dizziness
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 734 at risk

Adverse event: Speech disorder
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 734 at risk

Adverse event: Transient ischaemic attack
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 734 at risk

Adverse event: Abnormal behaviour
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 734 at risk

Adverse event: Psychotic disorder due to a general medical condition
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 734 at risk

Adverse event: Acute kidney injury
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 734 at risk

Adverse event: Haematuria
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 734 at risk

Adverse event: Nephrolithiasis
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 734 at risk

Adverse event: Ureterolithiasis
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 734 at risk

Adverse event: Acute respiratory failure
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 734 at risk

Adverse event: Dyspnoea exertional
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 734 at risk

Adverse event: Epistaxis
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 734 at risk

Adverse event: Hypercapnia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 734 at risk

Adverse event: Pneumonitis
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 734 at risk

Adverse event: Pulmonary embolism
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 734 at risk

Adverse event: Pulmonary oedema
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 734 at risk

Adverse event: Aortic stenosis
Serious: yes
Organ System: Vascular disorders
Frequency: 2 affected / 734 at risk

Adverse event: Deep vein thrombosis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 734 at risk

Adverse event: Hypertensive crisis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 734 at risk

Adverse event: Peripheral arterial occlusive disease
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 734 at risk

Adverse event: Peripheral artery aneurysm rupture
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 734 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 4 affected / 734 at risk

Adverse event: Atrial fibrillation
Serious: no
Organ System: Cardiac disorders
Frequency: 7 affected / 734 at risk

Adverse event: Vertigo
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 8 affected / 734 at risk

Adverse event: Cataract - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 12 affected / 734 at risk

Adverse event: Choroidal neovascularisation - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 12 affected / 734 at risk

Adverse event: Conjunctival haemorrhage - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 734 at risk

Adverse event: Conjunctival haemorrhage - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 36 affected / 734 at risk

Adverse event: Detachment of retinal pigment epithelium - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 734 at risk

Adverse event: Dry eye - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 22 affected / 734 at risk

Adverse event: Dry eye - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 26 affected / 734 at risk

Adverse event: Eye pain - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 734 at risk

Adverse event: Eye pain - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 30 affected / 734 at risk

Adverse event: Eye pruritus - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 734 at risk

Adverse event: Foreign body sensation in eyes - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 13 affected / 734 at risk

Adverse event: Lacrimation increased - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 734 at risk

Adverse event: Macular oedema - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 734 at risk

Adverse event: Neovascular age-related macular degeneration - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 39 affected / 734 at risk

Adverse event: Neovascular age-related macular degeneration - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 734 at risk

Adverse event: Posterior capsule opacification - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 8 affected / 734 at risk

Adverse event: Retinal depigmentation - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 734 at risk

Adverse event: Retinal haemorrhage - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 11 affected / 734 at risk

Adverse event: Retinal oedema - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 734 at risk

Adverse event: Retinal pigment epithelial tear - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 9 affected / 734 at risk

Adverse event: Subretinal fibrosis - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 734 at risk

Adverse event: Subretinal fluid - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 16 affected / 734 at risk

Adverse event: Vision blurred - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 734 at risk

Adverse event: Visual acuity reduced - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 8 affected / 734 at risk

Adverse event: Visual acuity reduced - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 37 affected / 734 at risk

Adverse event: Vitreous detachment - Fellow Eye
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 734 at risk

Adverse event: Vitreous detachment - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 14 affected / 734 at risk

Adverse event: Vitreous floaters - Study Eye
Serious: no
Organ System: Eye disorders
Frequency: 20 affected / 734 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 734 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 9 affected / 734 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 734 at risk

Adverse event: COVID-19
Serious: no
Organ System: Infections and infestations
Frequency: 25 affected / 734 at risk

Adverse event: Conjunctivitis - Fellow Eye
Serious: no
Organ System: Infections and infestations
Frequency: 8 affected / 734 at risk

Adverse event: Conjunctivitis - Study Eye
Serious: no
Organ System: Infections and infestations
Frequency: 10 affected / 734 at risk

Adverse event: Cystitis
Serious: no
Organ System: Infections and infestations
Frequency: 8 affected / 734 at risk

Adverse event: Hordeolum - Study Eye
Serious: no
Organ System: Infections and infestations
Frequency: 6 affected / 734 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 23 affected / 734 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 21 affected / 734 at risk

Adverse event: Fall
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 15 affected / 734 at risk

Adverse event: Intra-ocular injection complication - Study Eye
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 9 affected / 734 at risk

Adverse event: Vaccination complication
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 7 affected / 734 at risk

Adverse event: Gamma-glutamyltransferase increased
Serious: no
Organ System: Investigations
Frequency: 7 affected / 734 at risk

Adverse event: Intraocular pressure increased - Study Eye
Serious: no
Organ System: Investigations
Frequency: 15 affected / 734 at risk

Adverse event: Diabetes mellitus
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 5 affected / 734 at risk

Adverse event: Hypercholesterolaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 10 affected / 734 at risk

Adverse event: Hyperuricaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 5 affected / 734 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 16 affected / 734 at risk

Adverse event: Osteoarthritis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 8 affected / 734 at risk

Adverse event: Carpal tunnel syndrome
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 734 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 6 affected / 734 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 21 affected / 734 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 5 affected / 734 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 7 affected / 734 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 35 affected / 734 at risk