Study: NCT00072462

Adverse event: Magnetic resonance imaging
Serious: no
Organ System: Investigations
Frequency: 2 affected / 1489 at risk

Adverse event: X-ray
Serious: no
Organ System: Investigations
Frequency: 2 affected / 1489 at risk

Adverse event: Free fatty acids increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Glucose tolerance test
Serious: no
Organ System: Investigations
Frequency: 3 affected / 1489 at risk

Adverse event: Arthroscopy
Serious: no
Organ System: Investigations
Frequency: 7 affected / 1489 at risk

Adverse event: Bone densitometry
Serious: no
Organ System: Investigations
Frequency: 3 affected / 1489 at risk

Adverse event: Bone density decreased
Serious: no
Organ System: Investigations
Frequency: 42 affected / 1489 at risk

Adverse event: Acoustic stimulation tests
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Brain scan normal
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Scan brain
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Body height decreased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Body temperature increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Gastrointestinal examination
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Gynaecological examination
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Ophthalmological examination
Serious: no
Organ System: Investigations
Frequency: 4 affected / 1489 at risk

Adverse event: Orthopaedic examination
Serious: no
Organ System: Investigations
Frequency: 2 affected / 1489 at risk

Adverse event: Weight decreased
Serious: no
Organ System: Investigations
Frequency: 15 affected / 1489 at risk

Adverse event: Weight increased
Serious: no
Organ System: Investigations
Frequency: 133 affected / 1489 at risk

Adverse event: Cystoscopy
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Ultrasound kidney
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Biopsy breast
Serious: no
Organ System: Investigations
Frequency: 3 affected / 1489 at risk

Adverse event: Biopsy breast
Serious: no
Organ System: Investigations
Frequency: 12 affected / 1489 at risk

Adverse event: Biopsy cervix
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Biopsy endometrium
Serious: no
Organ System: Investigations
Frequency: 7 affected / 1489 at risk

Adverse event: Biopsy endometrium normal
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Biopsy testes normal
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Biopsy uterus
Serious: no
Organ System: Investigations
Frequency: 3 affected / 1489 at risk

Adverse event: Biopsy vagina
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Hysteroscopy
Serious: no
Organ System: Investigations
Frequency: 16 affected / 1489 at risk

Adverse event: Mammogram
Serious: no
Organ System: Investigations
Frequency: 3 affected / 1489 at risk

Adverse event: Mammogram abnormal
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Mammogram normal
Serious: no
Organ System: Investigations
Frequency: 2 affected / 1489 at risk

Adverse event: Smear cervix
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Smear cervix abnormal
Serious: no
Organ System: Investigations
Frequency: 6 affected / 1489 at risk

Adverse event: Ultrasound breast
Serious: no
Organ System: Investigations
Frequency: 10 affected / 1489 at risk

Adverse event: Ultrasound pelvis
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Ultrasound scan vagina
Serious: no
Organ System: Investigations
Frequency: 4 affected / 1489 at risk

Adverse event: Ultrasound uterus
Serious: no
Organ System: Investigations
Frequency: 2 affected / 1489 at risk

Adverse event: Chest X-ray
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Computerised tomogram thorax
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Laryngoscopy
Serious: no
Organ System: Investigations
Frequency: 1 affected / 1489 at risk

Adverse event: Arrhythmia
Serious: no
Organ System: Cardiac disorders
Frequency: 7 affected / 1489 at risk

Adverse event: Atrial fibrillation
Serious: no
Organ System: Cardiac disorders
Frequency: 5 affected / 1489 at risk

Adverse event: Atrial flutter
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Atrial tachycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Bradyarrhythmia
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Tachycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 9 affected / 1489 at risk

Adverse event: Cardiac disorder
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Cardiovascular disorder
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Cardiac disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Palpitations
Serious: no
Organ System: Cardiac disorders
Frequency: 18 affected / 1489 at risk

Adverse event: Aortic valve incompetence
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Aortic valve stenosis
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Mitral valve incompetence
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Chest pain
Serious: no
Organ System: Cardiac disorders
Frequency: 15 affected / 1489 at risk

Adverse event: Coronary artery stenosis
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Myocardial ischaemia
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Left ventricular failure
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Cardiomegaly
Serious: no
Organ System: Cardiac disorders
Frequency: 6 affected / 1489 at risk

Adverse event: Ventricular dysfunction
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Pericardial effusion
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Gastrointestinal angiodysplasia
Serious: no
Organ System: Congenital, familial and genetic disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Heart disease congenital
Serious: no
Organ System: Congenital, familial and genetic disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Cataract congenital
Serious: no
Organ System: Congenital, familial and genetic disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Haemangioma of retina
Serious: no
Organ System: Congenital, familial and genetic disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Keratosis follicular
Serious: no
Organ System: Congenital, familial and genetic disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Iron deficiency anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Coagulopathy
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Increased tendency to bruise
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Blood disorder
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Non-Hodgkin's lymphoma
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Lymphadenopathy
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Lymphoedema
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Carotid artery stenosis
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Cerebrovascular accident
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Haemorrhagic stroke
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Ischaemic stroke
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Giant cell arteritis
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Transient ischaemic attack
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Cranial nerve paralysis
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Facial paralysis
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Facial spasm
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Neuritis cranial
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Optic neuritis
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: VIth nerve paralysis
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Multiple sclerosis
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 61 affected / 1489 at risk

Adverse event: Migraine
Serious: no
Organ System: Nervous system disorders
Frequency: 10 affected / 1489 at risk

Adverse event: Amnesia
Serious: no
Organ System: Nervous system disorders
Frequency: 28 affected / 1489 at risk

Adverse event: Disturbance in attention
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Memory impairment
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Essential tremor
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Parkinson's disease
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Paralysis
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Torticollis
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Tremor
Serious: no
Organ System: Nervous system disorders
Frequency: 10 affected / 1489 at risk

Adverse event: Ageusia
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Analgesic therapy
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Aphonia
Serious: no
Organ System: Nervous system disorders
Frequency: 6 affected / 1489 at risk

Adverse event: Balance disorder
Serious: no
Organ System: Nervous system disorders
Frequency: 35 affected / 1489 at risk

Adverse event: Confusional state
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 8 affected / 1489 at risk

Adverse event: Dysgeusia
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Hypoaesthesia
Serious: no
Organ System: Nervous system disorders
Frequency: 10 affected / 1489 at risk

Adverse event: Lethargy
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Neuralgia
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Neurological symptom
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Paraesthesia
Serious: no
Organ System: Nervous system disorders
Frequency: 23 affected / 1489 at risk

Adverse event: Presyncope
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Restless legs syndrome
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Sensory disturbance
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Syncope
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Vertigo
Serious: no
Organ System: Nervous system disorders
Frequency: 17 affected / 1489 at risk

Adverse event: Carpal tunnel syndrome
Serious: no
Organ System: Nervous system disorders
Frequency: 13 affected / 1489 at risk

Adverse event: Guillain-Barre syndrome
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Nerve compression
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Neuropathy peripheral
Serious: no
Organ System: Nervous system disorders
Frequency: 14 affected / 1489 at risk

Adverse event: Seizure
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Narcolepsy
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Radiculopathy
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Sciatica
Serious: no
Organ System: Nervous system disorders
Frequency: 11 affected / 1489 at risk

Adverse event: Cataract
Serious: no
Organ System: Eye disorders
Frequency: 64 affected / 1489 at risk

Adverse event: Cataract congenital
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Entropion
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Corneal disorder
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Dry eye
Serious: no
Organ System: Eye disorders
Frequency: 49 affected / 1489 at risk

Adverse event: Eye disorder
Serious: no
Organ System: Eye disorders
Frequency: 35 affected / 1489 at risk

Adverse event: Eye pain
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 1489 at risk

Adverse event: Lacrimation increased
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 1489 at risk

Adverse event: Vitreous disorder
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Glaucoma
Serious: no
Organ System: Eye disorders
Frequency: 15 affected / 1489 at risk

Adverse event: Conjunctival haemorrhage
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Eye haemorrhage
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Blepharitis
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Conjunctivitis
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 1489 at risk

Adverse event: Episcleritis
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Eye irritation
Serious: no
Organ System: Eye disorders
Frequency: 8 affected / 1489 at risk

Adverse event: Ocular hyperaemia
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Haemangioma of retina
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Blepharospasm
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Macular degeneration
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 1489 at risk

Adverse event: Macular hole
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Retinal detachment
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Retinal tear
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Vitreous detachment
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Retinal vein occlusion
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Blindness
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Diplopia
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Myopia
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Vision blurred
Serious: no
Organ System: Eye disorders
Frequency: 18 affected / 1489 at risk

Adverse event: Visual acuity reduced
Serious: no
Organ System: Eye disorders
Frequency: 42 affected / 1489 at risk

Adverse event: Visual impairment
Serious: no
Organ System: Eye disorders
Frequency: 14 affected / 1489 at risk

Adverse event: Cholesteatoma
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Ear pain
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Deafness
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 5 affected / 1489 at risk

Adverse event: Meniere's disease
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Tinnitus
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Vertigo
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Middle ear adhesions
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Tympanic membrane perforation
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Abdominal hernia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Femoral hernia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Hiatus hernia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 1489 at risk

Adverse event: Inguinal hernia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Anal fissure
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Anorectal disorder
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Rectal prolapse
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Large intestine polyp
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Intestinal polyp
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Anorectal polyp
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Gingival disorder
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 5 affected / 1489 at risk

Adverse event: Toothache
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Diverticulitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 9 affected / 1489 at risk

Adverse event: Diverticulitis intestinal haemorrhagic
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Diverticulum
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Gastrointestinal disorder
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Gastrointestinal disorder
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 12 affected / 1489 at risk

Adverse event: Oesophageal disorder
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Rectal haemorrhage
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 9 affected / 1489 at risk

Adverse event: Colitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Colitis ischaemic
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Gastritis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 13 affected / 1489 at risk

Adverse event: Gastrointestinal inflammation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Inflammatory bowel disease
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Oesophagitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Colitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Gastrooesophageal reflux disease
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 18 affected / 1489 at risk

Adverse event: Change of bowel habit
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 42 affected / 1489 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 18 affected / 1489 at risk

Adverse event: Duodenogastric reflux
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Gastrooesophageal reflux disease
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Irritable bowel syndrome
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Abdominal discomfort
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Abdominal distension
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 11 affected / 1489 at risk

Adverse event: Abdominal mass
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 48 affected / 1489 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 24 affected / 1489 at risk

Adverse event: Dysphagia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Epigastric discomfort
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Flatulence
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 10 affected / 1489 at risk

Adverse event: Gastrointestinal pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 51 affected / 1489 at risk

Adverse event: Pelvic pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 1489 at risk

Adverse event: Intestinal obstruction
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Gastric ulcer
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Large intestine perforation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Haemorrhoids
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 1489 at risk

Adverse event: Rectal cancer
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Mouth ulceration
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 1489 at risk

Adverse event: Oral pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Abdominal adhesions
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Dry mouth
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 16 affected / 1489 at risk

Adverse event: Salivary gland cyst
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Salivary gland disorder
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Ageusia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Glossitis
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Tongue disorder
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Cystocele
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Calculus bladder
Serious: no
Organ System: Renal and urinary disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Cystitis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Dysuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 6 affected / 1489 at risk

Adverse event: Haematuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Micturition disorder
Serious: no
Organ System: Renal and urinary disorders
Frequency: 16 affected / 1489 at risk

Adverse event: Nocturia
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Pollakiuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 10 affected / 1489 at risk

Adverse event: Polyuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Renal colic
Serious: no
Organ System: Renal and urinary disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Stress urinary incontinence
Serious: no
Organ System: Renal and urinary disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Urethral stenosis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Urinary incontinence
Serious: no
Organ System: Renal and urinary disorders
Frequency: 15 affected / 1489 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Acne
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Actinic keratosis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 93 affected / 1489 at risk

Adverse event: Alopecia areata
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Basal cell carcinoma
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Blister
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Cellulitis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Dermal cyst
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 5 affected / 1489 at risk

Adverse event: Dry skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 28 affected / 1489 at risk

Adverse event: Eczema
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 18 affected / 1489 at risk

Adverse event: Erythema
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Erythema multiforme
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Hair disorder
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 11 affected / 1489 at risk

Adverse event: Hirsutism
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 12 affected / 1489 at risk

Adverse event: Hyperhidrosis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 18 affected / 1489 at risk

Adverse event: Lichen sclerosus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Morphoea
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Nail disorder
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 13 affected / 1489 at risk

Adverse event: Night sweats
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 341 affected / 1489 at risk

Adverse event: Onychoclasis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 16 affected / 1489 at risk

Adverse event: Photosensitivity reaction
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Pigmentation disorder
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 38 affected / 1489 at risk

Adverse event: Psoriasis
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 37 affected / 1489 at risk

Adverse event: Rash erythematous
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Rash pruritic
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Rosacea
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 6 affected / 1489 at risk

Adverse event: Scar pain
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Skin cancer
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Skin disorder
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 12 affected / 1489 at risk

Adverse event: Skin lesion
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Skin mass
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Skin swelling
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 6 affected / 1489 at risk

Adverse event: Skin ulcer
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Superficial spreading melanoma stage unspecified
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Swelling face
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Telangiectasia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Urticaria
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 11 affected / 1489 at risk

Adverse event: Exostosis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Osteitis deformans
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Osteopenia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Osteoporosis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 71 affected / 1489 at risk

Adverse event: Osteoporosis postmenopausal
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Spinal disorder
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: CREST syndrome
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Morphoea
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Polymyalgia rheumatica
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Sjogren's syndrome
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Ankle fracture
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Clavicle fracture
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Fibula fracture
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Foot fracture
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Hand fracture
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Hip fracture
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Lower limb fracture
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Osteoporotic fracture
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Pathological fracture
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Rib fracture
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Spinal fracture
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Wrist fracture
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Ankylosing spondylitis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 748 affected / 1489 at risk

Adverse event: Arthritis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 50 affected / 1489 at risk

Adverse event: Arthritis bacterial
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Arthropathy
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 9 affected / 1489 at risk

Adverse event: Haemarthrosis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Joint dislocation
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Joint effusion
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Joint stiffness
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 37 affected / 1489 at risk

Adverse event: Joint swelling
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 17 affected / 1489 at risk

Adverse event: Osteoarthritis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 53 affected / 1489 at risk

Adverse event: Periarthritis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Rheumatoid arthritis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 12 affected / 1489 at risk

Adverse event: Diffuse idiopathic skeletal hyperostosis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Spinal osteoarthritis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 6 affected / 1489 at risk

Adverse event: Spondylitis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Temporomandibular pain and dysfunction syndrome
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Fibromyalgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Muscle atrophy
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Muscle spasms
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 108 affected / 1489 at risk

Adverse event: Myalgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 106 affected / 1489 at risk

Adverse event: Periodic limb movement disorder
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Torticollis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Trismus
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Foot deformity
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Intervertebral disc protrusion
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 7 affected / 1489 at risk

Adverse event: Spinal flattening
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Sciatica
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Scoliosis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Axillary mass
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Back disorder
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 101 affected / 1489 at risk

Adverse event: Limb discomfort
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Musculoskeletal chest pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Musculoskeletal pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 95 affected / 1489 at risk

Adverse event: Musculoskeletal stiffness
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 18 affected / 1489 at risk

Adverse event: Neck pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Pain in extremity
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 80 affected / 1489 at risk

Adverse event: Plantar fasciitis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 5 affected / 1489 at risk

Adverse event: Foot deformity
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Bursitis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 11 affected / 1489 at risk

Adverse event: Synovial cyst
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Cartilage injury
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Costochondritis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Tendonitis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 8 affected / 1489 at risk

Adverse event: Trigger finger
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Breast cancer
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 6 affected / 1489 at risk

Adverse event: Adrenal gland cancer
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Adrenal disorder
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Adrenal mass
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Type 2 diabetes mellitus
Serious: no
Organ System: Endocrine disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Hypoparathyroidism
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Parathyroid disorder
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Goitre
Serious: no
Organ System: Endocrine disorders
Frequency: 5 affected / 1489 at risk

Adverse event: Hypothyroidism
Serious: no
Organ System: Endocrine disorders
Frequency: 16 affected / 1489 at risk

Adverse event: Thyroid cyst
Serious: no
Organ System: Endocrine disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Thyroid disorder
Serious: no
Organ System: Endocrine disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 6 affected / 1489 at risk

Adverse event: Weight fluctuation
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Bone metabolism disorder
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Osteoporosis
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Diabetic foot
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Fluid retention
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 5 affected / 1489 at risk

Adverse event: Hypokalaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Diabetes mellitus
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 13 affected / 1489 at risk

Adverse event: Diabetes mellitus inadequate control
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Hypoglycaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Type 1 diabetes mellitus
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Type 2 diabetes mellitus
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Haemochromatosis
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Iron deficiency anaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Iron overload
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Hypercholesterolaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 11 affected / 1489 at risk

Adverse event: Hyperlipidaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 8 affected / 1489 at risk

Adverse event: Gout
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Folate deficiency
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Vitamin B12 deficiency
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Vitamin B6 deficiency
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Vitamin D deficiency
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Bacterial infection
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 1489 at risk

Adverse event: Breast cellulitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 1489 at risk

Adverse event: Cellulitis
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 1489 at risk

Adverse event: Folliculitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 1489 at risk

Adverse event: Lyme disease
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 1489 at risk

Adverse event: Staphylococcal infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 1489 at risk

Adverse event: Fungal infection
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 1489 at risk

Adverse event: Oral candidiasis
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 1489 at risk

Adverse event: Vulvovaginal candidiasis
Serious: no
Organ System: Infections and infestations
Frequency: 42 affected / 1489 at risk

Adverse event: Acute sinusitis
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 1489 at risk

Adverse event: Arthritis infective
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 1489 at risk

Adverse event: Breast abscess
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 1489 at risk

Adverse event: Bronchiectasis
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 1489 at risk

Adverse event: Chronic sinusitis
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 1489 at risk

Adverse event: Cystitis
Serious: no
Organ System: Infections and infestations
Frequency: 14 affected / 1489 at risk

Adverse event: Diverticulitis
Serious: no
Organ System: Infections and infestations
Frequency: 5 affected / 1489 at risk

Adverse event: Eye infection
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 1489 at risk

Adverse event: Furuncle
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 1489 at risk

Adverse event: Gastroenteritis
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 1489 at risk

Adverse event: Hordeolum
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 1489 at risk

Adverse event: Postoperative wound infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 1489 at risk

Adverse event: Liver abscess
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 1489 at risk

Adverse event: Localised infection
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 1489 at risk

Adverse event: Lower respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 14 affected / 1489 at risk

Adverse event: Otitis externa
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 1489 at risk

Adverse event: Otitis media
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 1489 at risk

Adverse event: Paronychia
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 1489 at risk

Adverse event: Pharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 7 affected / 1489 at risk

Adverse event: Post procedural infection
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 1489 at risk

Adverse event: Respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 1489 at risk

Adverse event: Sepsis
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 1489 at risk

Adverse event: Sialoadenitis
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 1489 at risk

Adverse event: Skin infection
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 1489 at risk

Adverse event: Tonsillitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 1489 at risk

Adverse event: Tooth abscess
Serious: no
Organ System: Infections and infestations
Frequency: 7 affected / 1489 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 5 affected / 1489 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 32 affected / 1489 at risk

Adverse event: Wound infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 1489 at risk

Adverse event: Hepatitis viral
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 1489 at risk

Adverse event: Herpes zoster
Serious: no
Organ System: Infections and infestations
Frequency: 13 affected / 1489 at risk

Adverse event: Influenza
Serious: no
Organ System: Infections and infestations
Frequency: 14 affected / 1489 at risk

Adverse event: Chronic fatigue syndrome
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 1489 at risk

Adverse event: Vestibular neuronitis
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 1489 at risk

Adverse event: Viral infection
Serious: no
Organ System: Infections and infestations
Frequency: 8 affected / 1489 at risk

Adverse event: Aneurysm
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Aortic stenosis
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Carotid artery occlusion
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Circulatory collapse
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Deep vein thrombosis
Serious: no
Organ System: Vascular disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Dizziness
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Embolism
Serious: no
Organ System: Vascular disorders
Frequency: 5 affected / 1489 at risk

Adverse event: Epistaxis
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Essential hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 54 affected / 1489 at risk

Adverse event: Femoral artery aneurysm
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Haematoma
Serious: no
Organ System: Vascular disorders
Frequency: 8 affected / 1489 at risk

Adverse event: Haemorrhage intracranial
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Hot flush
Serious: no
Organ System: Vascular disorders
Frequency: 184 affected / 1489 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 22 affected / 1489 at risk

Adverse event: Hypotension
Serious: no
Organ System: Vascular disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Ischaemic stroke
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Lymphoedema
Serious: no
Organ System: Vascular disorders
Frequency: 8 affected / 1489 at risk

Adverse event: Malignant hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Peripheral coldness
Serious: no
Organ System: Vascular disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Peripheral vascular disorder
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Phlebitis
Serious: no
Organ System: Vascular disorders
Frequency: 7 affected / 1489 at risk

Adverse event: Postmenopausal haemorrhage
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Pulmonary embolism
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Syncope
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Giant cell arteritis
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Superficial vein thrombosis
Serious: no
Organ System: Vascular disorders
Frequency: 6 affected / 1489 at risk

Adverse event: Transient ischaemic attack
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Varicose ulceration
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Varicose vein
Serious: no
Organ System: Vascular disorders
Frequency: 9 affected / 1489 at risk

Adverse event: Vasculitis
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Venous thrombosis
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Acupuncture
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Adrenal gland operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Anal polypectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Angioplasty
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 1489 at risk

Adverse event: Appendicectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Arthroscopic surgery
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Bladder operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Bone operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Breast cyst drainage
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 1489 at risk

Adverse event: Breast conserving surgery
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 1489 at risk

Adverse event: Bunion operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 8 affected / 1489 at risk

Adverse event: Cancer surgery
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Cardiac ablation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 1489 at risk

Adverse event: Carpal tunnel decompression
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 1489 at risk

Adverse event: Cataract operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 26 affected / 1489 at risk

Adverse event: Cervical polypectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Chemotherapy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 1489 at risk

Adverse event: Cholecystectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 7 affected / 1489 at risk

Adverse event: Large intestinal polypectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 6 affected / 1489 at risk

Adverse event: Colonoscopy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 4 affected / 1489 at risk

Adverse event: Colostomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 1489 at risk

Adverse event: Colporrhaphy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Coronary artery bypass
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Dental implantation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Dupuytren's contracture operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Ear operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Emergency care
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 1489 at risk

Adverse event: Endocervical curettage
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Ethmoid sinus surgery
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Eye operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 1489 at risk

Adverse event: Foot operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 1489 at risk

Adverse event: Gallbladder operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Haemorrhoid operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Hand repair operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Heart valve replacement
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 1489 at risk

Adverse event: Hip arthroplasty
Serious: no
Organ System: Surgical and medical procedures
Frequency: 10 affected / 1489 at risk

Adverse event: Hip surgery
Serious: no
Organ System: Surgical and medical procedures
Frequency: 4 affected / 1489 at risk

Adverse event: Hospitalisation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 1489 at risk

Adverse event: Hysterectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 17 affected / 1489 at risk

Adverse event: Ileostomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Incisional hernia repair
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 1489 at risk

Adverse event: Inguinal hernia repair
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Intestinal resection
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Intrauterine contraception
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Joint manipulation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Knee arthroplasty
Serious: no
Organ System: Surgical and medical procedures
Frequency: 13 affected / 1489 at risk

Adverse event: Knee operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 1489 at risk

Adverse event: Large intestine operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Laryngeal polypectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Limb operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 1489 at risk

Adverse event: Lipoma excision
Serious: no
Organ System: Surgical and medical procedures
Frequency: 7 affected / 1489 at risk

Adverse event: Pulmonary resection
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Lymphadenectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Mammoplasty
Serious: no
Organ System: Surgical and medical procedures
Frequency: 4 affected / 1489 at risk

Adverse event: Mastectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 4 affected / 1489 at risk

Adverse event: Meniscus removal
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 1489 at risk

Adverse event: Mitral valve replacement
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Mole excision
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Nasal operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Nerve block
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Oophorectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 1489 at risk

Adverse event: Oophorectomy bilateral
Serious: no
Organ System: Surgical and medical procedures
Frequency: 5 affected / 1489 at risk

Adverse event: Open reduction of fracture
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Ovarian cystectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Parathyroidectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Pelvic floor repair
Serious: no
Organ System: Surgical and medical procedures
Frequency: 4 affected / 1489 at risk

Adverse event: Physiotherapy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Plastic surgery
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Polypectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 12 affected / 1489 at risk

Adverse event: Radiotherapy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 1489 at risk

Adverse event: Retinal laser coagulation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Retinal operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 1489 at risk

Adverse event: Salpingectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 1489 at risk

Adverse event: Salpingo-oophorectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Salpingo-oophorectomy bilateral
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 1489 at risk

Adverse event: Shoulder arthroplasty
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Shoulder operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 1489 at risk

Adverse event: Sinus operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Skin lesion removal
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 1489 at risk

Adverse event: Skin neoplasm excision
Serious: no
Organ System: Surgical and medical procedures
Frequency: 4 affected / 1489 at risk

Adverse event: Spinal decompression
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 1489 at risk

Adverse event: Spinal operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 1489 at risk

Adverse event: Surgery
Serious: no
Organ System: Surgical and medical procedures
Frequency: 4 affected / 1489 at risk

Adverse event: Therapeutic skin care topical
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Thoracotomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Thyroid operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Thyroidectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 3 affected / 1489 at risk

Adverse event: Toe amputation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Tooth extraction
Serious: no
Organ System: Surgical and medical procedures
Frequency: 6 affected / 1489 at risk

Adverse event: Tumour excision
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Umbilical hernia repair
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Uterine cystectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Uterine dilation and curettage
Serious: no
Organ System: Surgical and medical procedures
Frequency: 4 affected / 1489 at risk

Adverse event: Venous ligation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 2 affected / 1489 at risk

Adverse event: Venous operation
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Vocal cordectomy
Serious: no
Organ System: Surgical and medical procedures
Frequency: 1 affected / 1489 at risk

Adverse event: Benign breast neoplasm
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 11 affected / 1489 at risk

Adverse event: Breast cyst
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 2 affected / 1489 at risk

Adverse event: Fibroadenoma of breast
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 8 affected / 1489 at risk

Adverse event: Breast cancer in situ
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 2 affected / 1489 at risk

Adverse event: Breast cancer metastatic
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Melanocytic naevus
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Seborrhoeic keratosis
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Skin papilloma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Colon cancer
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 2 affected / 1489 at risk

Adverse event: Gastrointestinal carcinoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 2 affected / 1489 at risk

Adverse event: Intestinal adenocarcinoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Oesophageal carcinoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Rectal cancer
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Focal nodular hyperplasia
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Hepatic cancer
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Myelodysplastic syndrome
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Lymphoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Non-Hodgkin's lymphoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Mesothelioma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Metastases to lung
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Metastases to lymph nodes
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Metastases to peritoneum
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Metastasis
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Adenoma benign
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Cholesteatoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Cyst
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Polyp
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 3 affected / 1489 at risk

Adverse event: Malignant neoplasm of unknown primary site
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Metastatic neoplasm
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Recurrent cancer
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Squamous cell carcinoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 2 affected / 1489 at risk

Adverse event: Neuroma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Intracranial meningioma malignant
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 2 affected / 1489 at risk

Adverse event: Cervical polyp
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Degeneration of uterine leiomyoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Ovarian cyst
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 3 affected / 1489 at risk

Adverse event: Uterine cyst
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Uterine leiomyoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 6 affected / 1489 at risk

Adverse event: Uterine polyp
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 3 affected / 1489 at risk

Adverse event: Vaginal polyp
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Vulval polyp
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Endometrial cancer stage I
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Ovarian cancer
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 2 affected / 1489 at risk

Adverse event: Uterine cancer
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 2 affected / 1489 at risk

Adverse event: Benign lung neoplasm
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Nasal polyps
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Adenosquamous cell lung cancer
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Bronchial carcinoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Lung adenocarcinoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Lung carcinoma cell type unspecified recurrent
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 2 affected / 1489 at risk

Adverse event: Lung carcinoma cell type unspecified stage 0
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Thymoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Tonsil cancer
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Basal cell carcinoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 9 affected / 1489 at risk

Adverse event: Malignant melanoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Malignant melanoma stage 0
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Melanoma recurrent
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Skin cancer
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 4 affected / 1489 at risk

Adverse event: Superficial spreading melanoma stage unspecified
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Lipoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 1489 at risk

Adverse event: Hypersensitivity
Serious: no
Organ System: Immune system disorders
Frequency: 10 affected / 1489 at risk

Adverse event: Antiphospholipid syndrome
Serious: no
Organ System: Immune system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Polymyalgia rheumatica
Serious: no
Organ System: Immune system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Rheumatoid arthritis
Serious: no
Organ System: Immune system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Polyarteritis nodosa
Serious: no
Organ System: Immune system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Giant cell arteritis
Serious: no
Organ System: Immune system disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Bereavement
Serious: no
Organ System: Social circumstances
Frequency: 1 affected / 1489 at risk

Adverse event: Ex-tobacco user
Serious: no
Organ System: Social circumstances
Frequency: 1 affected / 1489 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 6 affected / 1489 at risk

Adverse event: Asthenia
Serious: no
Organ System: General disorders
Frequency: 25 affected / 1489 at risk

Adverse event: Axillary pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Chest discomfort
Serious: no
Organ System: General disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Chest pain
Serious: no
Organ System: General disorders
Frequency: 6 affected / 1489 at risk

Adverse event: Chills
Serious: no
Organ System: General disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Disease recurrence
Serious: no
Organ System: General disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Hernia
Serious: no
Organ System: General disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Hot flush
Serious: no
Organ System: General disorders
Frequency: 14 affected / 1489 at risk

Adverse event: Influenza like illness
Serious: no
Organ System: General disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Irritability
Serious: no
Organ System: General disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Lethargy
Serious: no
Organ System: General disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Malaise
Serious: no
Organ System: General disorders
Frequency: 177 affected / 1489 at risk

Adverse event: Night sweats
Serious: no
Organ System: General disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Oedema
Serious: no
Organ System: General disorders
Frequency: 28 affected / 1489 at risk

Adverse event: Oedema peripheral
Serious: no
Organ System: General disorders
Frequency: 9 affected / 1489 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Polyp
Serious: no
Organ System: General disorders
Frequency: 6 affected / 1489 at risk

Adverse event: Thirst
Serious: no
Organ System: General disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Adverse drug reaction
Serious: no
Organ System: General disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Cyst
Serious: no
Organ System: General disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Dysplasia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Fat necrosis
Serious: no
Organ System: General disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Fibrosis
Serious: no
Organ System: General disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Hyperplasia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Agitation
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Aggression
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 22 affected / 1489 at risk

Adverse event: Bipolar I disorder
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Depression
Serious: no
Organ System: Psychiatric disorders
Frequency: 70 affected / 1489 at risk

Adverse event: Eating disorder
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Emotional disorder
Serious: no
Organ System: Psychiatric disorders
Frequency: 36 affected / 1489 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 93 affected / 1489 at risk

Adverse event: Loss of libido
Serious: no
Organ System: Psychiatric disorders
Frequency: 12 affected / 1489 at risk

Adverse event: Mental disorder
Serious: no
Organ System: Psychiatric disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Nervousness
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Neurosis
Serious: no
Organ System: Psychiatric disorders
Frequency: 5 affected / 1489 at risk

Adverse event: Nightmare
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Phobia
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Restlessness
Serious: no
Organ System: Psychiatric disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Stress
Serious: no
Organ System: Psychiatric disorders
Frequency: 5 affected / 1489 at risk

Adverse event: Adnexa uteri pain
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Arthritis climacteric
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Benign breast neoplasm
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Breast abscess
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Breast calcifications
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Breast cancer in situ
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Breast cyst
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 7 affected / 1489 at risk

Adverse event: Breast discharge
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 5 affected / 1489 at risk

Adverse event: Breast disorder
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 18 affected / 1489 at risk

Adverse event: Breast hyperplasia
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Breast necrosis
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Breast pain
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 66 affected / 1489 at risk

Adverse event: Cervical polyp
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 11 affected / 1489 at risk

Adverse event: Cystocele
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Dyspareunia
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 11 affected / 1489 at risk

Adverse event: Endometrial disorder
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Endometrial hyperplasia
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 18 affected / 1489 at risk

Adverse event: Endometrial hypertrophy
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 34 affected / 1489 at risk

Adverse event: Endometriosis
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Fibrocystic breast disease
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 8 affected / 1489 at risk

Adverse event: Galactorrhoea
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Hot flush
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 898 affected / 1489 at risk

Adverse event: Menopausal symptoms
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Heavy menstrual bleeding
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Intermenstrual bleeding
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 20 affected / 1489 at risk

Adverse event: Night sweats
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 74 affected / 1489 at risk

Adverse event: Nipple disorder
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Ovarian cyst
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 9 affected / 1489 at risk

Adverse event: Ovarian mass
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Pelvic pain
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Perineal pain
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Postmenopausal haemorrhage
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 12 affected / 1489 at risk

Adverse event: Premenstrual syndrome
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Sexual dysfunction
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Uterine cyst
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Uterine fibrosis
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Uterine haemorrhage
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Uterine leiomyoma
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Uterine polyp
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 25 affected / 1489 at risk

Adverse event: Uterine prolapse
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Uterine spasm
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Vaginal cyst
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Vaginal discharge
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 140 affected / 1489 at risk

Adverse event: Vaginal disorder
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 22 affected / 1489 at risk

Adverse event: Vaginal haemorrhage
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 78 affected / 1489 at risk

Adverse event: Vulvovaginal inflammation
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Vaginal polyp
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Vaginal prolapse
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 11 affected / 1489 at risk

Adverse event: Vulvovaginal swelling
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Vulval abscess
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Vulval polyp
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Vulvovaginal dryness
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 166 affected / 1489 at risk

Adverse event: Vulvovaginal pruritus
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 47 affected / 1489 at risk

Adverse event: Asthma
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 12 affected / 1489 at risk

Adverse event: Bronchitis chronic
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Chest discomfort
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Chest pain
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Chronic obstructive pulmonary disease
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 6 affected / 1489 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 24 affected / 1489 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 30 affected / 1489 at risk

Adverse event: Epistaxis
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Increased upper airway secretion
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Pneumonia
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Lower respiratory tract infection
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 53 affected / 1489 at risk

Adverse event: Lung cancer metastatic
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Multifocal micronodular pneumocyte hyperplasia
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Nasal congestion
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Nasal discomfort
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Nasal dryness
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Nasal polyps
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Pleuritic pain
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Pneumonia
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Pulmonary arterial hypertension
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Pulmonary embolism
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Pulmonary hypertension
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Respiratory disorder
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 1489 at risk

Adverse event: Rhinitis allergic
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 5 affected / 1489 at risk

Adverse event: Rhinorrhoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Sleep apnoea syndrome
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 25 affected / 1489 at risk

Adverse event: Throat tightness
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Tonsillar disorder
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Tonsillitis
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 7 affected / 1489 at risk

Adverse event: Cholecystitis
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 1489 at risk

Adverse event: Cholelithiasis
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 8 affected / 1489 at risk

Adverse event: Haemochromatosis
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 2 affected / 1489 at risk

Adverse event: Hepatitis
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Liver disorder
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 3 affected / 1489 at risk

Adverse event: Hepatobiliary cancer in situ
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 1489 at risk