Study: NCT00313846

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Notes: Systematic and nonsystematic assessment
Frequency: 3 affected / 162 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Notes: Systematic and nonsystematic assessment
Frequency: 6 affected / 162 at risk

Adverse event: Application site erythema
Serious: no
Organ System: General disorders
Notes: Systematic and nonsystematic assessment
Frequency: 5 affected / 162 at risk

Adverse event: Application site pruritus
Serious: no
Organ System: General disorders
Notes: Systematic and nonsystematic assessment
Frequency: 4 affected / 162 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Notes: Systematic and nonsystematic assessment
Frequency: 15 affected / 162 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Notes: Systematic and nonsystematic assessment
Frequency: 4 affected / 162 at risk

Adverse event: Transient ischaemic attack
Serious: yes
Organ System: Nervous system disorders
Notes: Systematic and nonsystematic assessment
Frequency: 1 affected / 164 at risk

Adverse event: Numbness left side of face
Serious: yes
Organ System: Nervous system disorders
Notes: Systematic and nonsystematic assessment
Frequency: 1 affected / 164 at risk

Adverse event: Worsening of hypertension
Serious: yes
Organ System: Vascular disorders
Notes: Systematic and nonsystematic assessment
Frequency: 1 affected / 164 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Notes: Systematic and nonsystematic assessment
Frequency: 12 affected / 164 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Notes: Systematic and nonsystematic assessment
Frequency: 10 affected / 164 at risk

Adverse event: Vomiting not otherwise specified (NOS)
Serious: no
Organ System: Gastrointestinal disorders
Notes: Systematic and nonsystematic assessment
Frequency: 1 affected / 164 at risk

Adverse event: Application site erythema
Serious: no
Organ System: General disorders
Notes: Systematic and nonsystematic assessment
Frequency: 9 affected / 164 at risk

Adverse event: Application site pruritus
Serious: no
Organ System: General disorders
Notes: Systematic and nonsystematic assessment
Frequency: 8 affected / 164 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Notes: Systematic and nonsystematic assessment
Frequency: 7 affected / 164 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Notes: Systematic and nonsystematic assessment
Frequency: 5 affected / 164 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Notes: Systematic and nonsystematic assessment
Frequency: 2 affected / 164 at risk

Adverse event: Intermittent complete heart block
Serious: yes
Organ System: Cardiac disorders
Notes: Systematic and nonsystematic assessment
Frequency: 1 affected / 529 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Notes: Systematic and nonsystematic assessment
Frequency: 1 affected / 529 at risk

Adverse event: Left foot cellulitis
Serious: yes
Organ System: Infections and infestations
Notes: Systematic and nonsystematic assessment
Frequency: 1 affected / 529 at risk

Adverse event: Upper respiratory tract infection
Serious: yes
Organ System: Infections and infestations
Notes: Systematic and nonsystematic assessment
Frequency: 1 affected / 529 at risk

Adverse event: Elevated blood pressure
Serious: yes
Organ System: Investigations
Notes: Systematic and nonsystematic assessment
Frequency: 1 affected / 529 at risk

Adverse event: Cerebrovascular accident
Serious: yes
Organ System: Nervous system disorders
Notes: Systematic and nonsystematic assessment
Frequency: 1 affected / 529 at risk

Adverse event: Tremor
Serious: yes
Organ System: Nervous system disorders
Notes: Systematic and nonsystematic assessment
Frequency: 1 affected / 529 at risk

Adverse event: Anxiety
Serious: yes
Organ System: Psychiatric disorders
Notes: Systematic and nonsystematic assessment
Frequency: 1 affected / 529 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Systematic and nonsystematic assessment
Frequency: 1 affected / 529 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Notes: Systematic and nonsystematic assessment
Frequency: 113 affected / 529 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Notes: Systematic and nonsystematic assessment
Frequency: 41 affected / 529 at risk

Adverse event: Vomiting not otherwise specified (NOS)
Serious: no
Organ System: Gastrointestinal disorders
Notes: Systematic and nonsystematic assessment
Frequency: 36 affected / 529 at risk

Adverse event: Application site erythema
Serious: no
Organ System: General disorders
Notes: Systematic and nonsystematic assessment
Frequency: 6 affected / 529 at risk

Adverse event: Application site pruritus
Serious: no
Organ System: General disorders
Notes: Systematic and nonsystematic assessment
Frequency: 28 affected / 529 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Notes: Systematic and nonsystematic assessment
Frequency: 65 affected / 529 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Notes: Systematic and nonsystematic assessment
Frequency: 55 affected / 529 at risk

Adverse event: Somnolence
Serious: no
Organ System: Nervous system disorders
Notes: Systematic and nonsystematic assessment
Frequency: 41 affected / 529 at risk