TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT00956943

Adverse event: Influenza
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 44 at risk
Study: NCT00957359

Adverse event: Transient Anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 29 at risk

Adverse event: elevations in BP and HR
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 29 at risk
Study: NCT00957528

Adverse event: Saphenous vein clot
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 8 at risk

Adverse event: Vertigo
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 8 at risk

Adverse event: Saphenous vein clot
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 8 at risk

Adverse event: Vertigo
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 8 at risk
Study: NCT00957658

Adverse event: Non-operative site
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 234 at risk

Adverse event: Non-operative site
Serious: yes
Organ System: Cardiac disorders
Frequency: 10 affected / 234 at risk

Adverse event: Non-operative site
Serious: yes
Organ System: Endocrine disorders
Frequency: 1 affected / 234 at risk

Adverse event: Non-operative site
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 7 affected / 234 at risk

Adverse event: Non-operative site
Serious: yes
Organ System: General disorders
Frequency: 4 affected / 234 at risk

Adverse event: Non-operative site
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 234 at risk

Adverse event: Operative site
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 234 at risk

Adverse event: Non-operative site
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 234 at risk

Adverse event: Operative site
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 3 affected / 234 at risk

Adverse event: Non-operative site
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 8 affected / 234 at risk

Adverse event: Operative site
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 16 affected / 234 at risk

Adverse event: Non-operative Site
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 6 affected / 234 at risk

Adverse event: Non-operative site
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 234 at risk

Adverse event: Non-operative site
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 3 affected / 234 at risk

Adverse event: Non-operative site
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 234 at risk

Adverse event: Non-operative site
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 234 at risk

Adverse event: Non-operative site
Serious: yes
Organ System: Vascular disorders
Frequency: 6 affected / 234 at risk

Adverse event: Operative site
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 234 at risk

Adverse event: Non-operative site
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 234 at risk

Adverse event: Operative site Musculoskeletal and Connective tissue disorders
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 54 affected / 234 at risk
Study: NCT00957723

Adverse event: Operative Site
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 440 at risk

Adverse event: Operative-Site
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 13 affected / 440 at risk

Adverse event: Operative-Site
Serious: yes
Organ System: Nervous system disorders
Frequency: 2 affected / 440 at risk

Adverse event: Operative-Site
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 440 at risk

Adverse event: Operative-Site
Serious: yes
Organ System: Vascular disorders
Frequency: 5 affected / 440 at risk

Adverse event: Operative Site
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 79 affected / 440 at risk

Adverse event: Systemic
Serious: yes
Organ System: Cardiac disorders
Frequency: 22 affected / 411 at risk

Adverse event: Systemic
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 411 at risk

Adverse event: Systemic
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 16 affected / 411 at risk

Adverse event: Systemic
Serious: yes
Organ System: General disorders
Frequency: 4 affected / 411 at risk

Adverse event: Systemic
Serious: yes
Organ System: Infections and infestations
Frequency: 5 affected / 411 at risk

Adverse event: Systemic
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 411 at risk

Adverse event: Systemic
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 19 affected / 411 at risk

Adverse event: Systemic
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 411 at risk

Adverse event: Systemic
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 6 affected / 411 at risk

Adverse event: Systemic
Serious: yes
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 411 at risk

Adverse event: Systemic
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 411 at risk

Adverse event: Systemic
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 411 at risk

Adverse event: Systemic
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 13 affected / 411 at risk

Adverse event: Systemic
Serious: yes
Organ System: Nervous system disorders
Frequency: 3 affected / 411 at risk

Adverse event: Systemic
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 11 affected / 411 at risk

Adverse event: Systemic
Serious: yes
Organ System: Vascular disorders
Frequency: 10 affected / 411 at risk
Study: NCT00957853

Adverse event: Acneiform rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 4 at risk

Adverse event: Dry skin
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 4 at risk

Adverse event: Pain(headache)
Serious: no
Organ System: General disorders
Frequency: 2 affected / 4 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 1 affected / 6 at risk

Adverse event: Hot flush
Serious: no
Organ System: General disorders
Frequency: 1 affected / 6 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 6 at risk

Adverse event: Acneiform rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 5 at risk

Adverse event: Fever without Neutropenia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 5 at risk

Adverse event: Mucositis-symptomatic
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 5 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 5 at risk

Adverse event: Rigors/Chills
Serious: no
Organ System: General disorders
Frequency: 1 affected / 5 at risk
Study: NCT00957931

Adverse event: Graft failure with autologous recovery
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 6 at risk

Adverse event: SOS
Serious: yes
Organ System: Hepatobiliary disorders
Notes: SOS = Sinusoidal obstruction syndrome
Frequency: 1 affected / 6 at risk

Adverse event: EBV-PTLD
Serious: yes
Organ System: Immune system disorders
Notes: EPV = Epstein-Barr virus post-transplant lymphoproliferative disorder
Frequency: 1 affected / 6 at risk

Adverse event: Grade II GVHD
Serious: yes
Organ System: Immune system disorders
Notes: GVHD = Graft-versus-host disease
Frequency: 1 affected / 6 at risk

Adverse event: Grade III acute GVHD
Serious: yes
Organ System: Immune system disorders
Frequency: 1 affected / 6 at risk

Adverse event: Adenovirus reactivation
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 6 at risk

Adverse event: BK virus reactivation
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 6 at risk

Adverse event: CMV pneumonitis
Serious: yes
Organ System: Infections and infestations
Notes: CMV = Cytomegalovirus
Frequency: 1 affected / 6 at risk

Adverse event: CMV reactivation
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 6 at risk

Adverse event: Cytomegalovirus viraemia
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 6 at risk

Adverse event: Disseminated toxoplasmosis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 6 at risk

Adverse event: Gram-negative septic shock
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 6 at risk

Adverse event: HHV-6 viremia
Serious: yes
Organ System: Infections and infestations
Notes: HHV-6 = Human Herpesvirus 6
Frequency: 1 affected / 6 at risk

Adverse event: Klebsiella and enterobacter
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 6 at risk

Adverse event: Klebsiella bacteraemia
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 6 at risk

Adverse event: Intracranial bleeding
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 6 at risk

Adverse event: Haemorrhage intracranial
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 6 at risk

Adverse event: PRES
Serious: yes
Organ System: Nervous system disorders
Notes: PRES = Posterior reversible encephalopathy syndrome
Frequency: 1 affected / 6 at risk
Study: NCT00957944

Adverse event: Application site pruritus
Serious: no
Organ System: General disorders
Frequency: 4 affected / 39 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 1 affected / 39 at risk

Adverse event: Hot flush
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 39 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 40 at risk

Adverse event: Application site pruritus
Serious: no
Organ System: General disorders
Frequency: 3 affected / 40 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 40 at risk

Adverse event: Sleep disorder
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 40 at risk
Study: NCT00958009

Adverse event: Chest pain
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 109 at risk

Adverse event: Angina pectoris
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 109 at risk

Adverse event: Pancreatitis acute
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 109 at risk

Adverse event: Seizure
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 109 at risk

Adverse event: Hypertension
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 109 at risk

Adverse event: Influenza like illness
Serious: no
Organ System: General disorders
Frequency: 26 affected / 109 at risk

Adverse event: Injection site erythema
Serious: no
Organ System: General disorders
Frequency: 39 affected / 109 at risk

Adverse event: Injection site haematoma
Serious: no
Organ System: General disorders
Frequency: 13 affected / 109 at risk

Adverse event: Injection site pain
Serious: no
Organ System: General disorders
Frequency: 27 affected / 109 at risk

Adverse event: Injection site swelling
Serious: no
Organ System: General disorders
Frequency: 8 affected / 109 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 6 affected / 109 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 7 affected / 109 at risk
Study: NCT00958035

Adverse event: Hepatic failure
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 46 at risk

Adverse event: Eyelids pruritus
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 46 at risk

Adverse event: Skin hyperpigmentation
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 11 affected / 46 at risk

Adverse event: Musculoskeletal chest pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 43 at risk

Adverse event: Eyelids pruritus
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 43 at risk

Adverse event: Skin hyperpigmentation
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 43 at risk
Study: NCT00958165

Adverse event: Phrenic nerve injury
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 72 at risk

Adverse event: Air embolism
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 72 at risk

Adverse event: Cardiac tamponade
Serious: yes
Organ System: Cardiac disorders
Frequency: 4 affected / 72 at risk

Adverse event: Pericardial effusion
Serious: yes
Organ System: Cardiac disorders
Frequency: 3 affected / 72 at risk
Study: NCT00958191

Adverse event: Operative Site
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 240 at risk

Adverse event: Operative Site
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 240 at risk

Adverse event: Operative Site
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 11 affected / 240 at risk

Adverse event: Operative Site
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 240 at risk

Adverse event: Operative Site
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 19 affected / 240 at risk

Adverse event: Operative Site
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 45 affected / 240 at risk

Adverse event: Non-operative Site
Serious: yes
Organ System: Cardiac disorders
Frequency: 3 affected / 221 at risk

Adverse event: Non-operative Site
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 221 at risk

Adverse event: Non-operative Site
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 221 at risk

Adverse event: Non-operative Site
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 221 at risk

Adverse event: Non-operative Site
Serious: yes
Organ System: Infections and infestations
Frequency: 4 affected / 221 at risk

Adverse event: Non-operative Site
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 13 affected / 221 at risk

Adverse event: Non-operative Site
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 4 affected / 221 at risk

Adverse event: Non-operative Site
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 221 at risk

Adverse event: Non-operative Site
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 221 at risk

Adverse event: Non-operative Site
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 3 affected / 221 at risk

Adverse event: Non-operative Site
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 221 at risk

Adverse event: Non-operative Site
Serious: yes
Organ System: Vascular disorders
Frequency: 2 affected / 221 at risk

Adverse event: Non-operative Site
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 17 affected / 221 at risk

Adverse event: Non-operative Site
Serious: no
Organ System: Infections and infestations
Frequency: 13 affected / 221 at risk

Adverse event: Non-operative Site
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 41 affected / 221 at risk
Study: NCT00958282

Adverse event: Angina pectoris
Serious: yes
Organ System: Cardiac disorders
Notes: A patient was hospitalized for chest pain and diagnosed with angina that was possibly related to the study drug. He did not continue in the study. He was assigned to the LDX condition.
Frequency: 1 affected / 22 at risk

Adverse event: Psychotic disorder
Serious: yes
Organ System: Psychiatric disorders
Notes: A subject was hospitalized with psychosis (assigned to the placebo condition). She had apparently binged on cocaine prior to her psychotic episode. In addition she failed to reveal to study staff that she was diagnosed with schizoaffective disorder.
Frequency: 1 affected / 21 at risk
Study: NCT00958308

Adverse event: Fever and hematochezia
Serious: no
Organ System: General disorders
Frequency: 2 affected / 84 at risk

Adverse event: Fever and hematochezia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 86 at risk
Study: NCT00958347

Adverse event: Non-operative Site Cardiac Disorders
Serious: yes
Organ System: Cardiac disorders
Frequency: 13 affected / 226 at risk

Adverse event: Non-operative Site Gastrointestinal Disorders
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 226 at risk

Adverse event: Non-operative Site Infections and Infestations
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 226 at risk

Adverse event: Operative Site Infection and Infestation
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 226 at risk

Adverse event: Non-operative Site Musculoskeletal and Connective Tissue Disorders
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 9 affected / 226 at risk

Adverse event: Operative Site Musculoskeletal and Connective Tissue Disorders
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 81 affected / 226 at risk

Adverse event: Non-Operative Site Neoplasms Benign,Malignant,and Unspecified
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 7 affected / 226 at risk

Adverse event: Non-operative Site Renal and Urinary Disorders
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 226 at risk

Adverse event: Operative Site Skin and Subcutaneous Tissue Disorders
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 226 at risk

Adverse event: Non-operative Site Vascular Disorders
Serious: yes
Organ System: Vascular disorders
Frequency: 9 affected / 226 at risk

Adverse event: Non-operative Site Musculoskeletal and Connective Tissue Disorder
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 19 affected / 226 at risk

Adverse event: Operative Site Musculoskeletal and Connective Tissue Disorder
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 59 affected / 226 at risk
Study: NCT00958360

Adverse event: Non-study related Death
Serious: yes
Organ System: General disorders
Frequency: 7 affected / 163 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: Cardiac disorders
Frequency: 4 affected / 163 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 163 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: General disorders
Frequency: 5 affected / 163 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 163 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 2 affected / 163 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 163 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: Vascular disorders
Frequency: 3 affected / 163 at risk

Adverse event: Eye haemorrhage
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 163 at risk

Adverse event: CME
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 163 at risk

Adverse event: Non-study related Death
Serious: yes
Organ System: General disorders
Frequency: 8 affected / 160 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 160 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: Endocrine disorders
Frequency: 1 affected / 160 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 160 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 160 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: General disorders
Frequency: 9 affected / 160 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 3 affected / 160 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 160 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 160 at risk

Adverse event: Non-study related Prolonged Hospitalization
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 160 at risk

Adverse event: other health reason
Serious: no
Organ System: General disorders
Frequency: 1 affected / 160 at risk
Study: NCT00958581

Adverse event: Pulmonary embolism
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 61 at risk

Adverse event: Pulmonary embolism
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 61 at risk

Adverse event: Pulmonary embolism
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 55 at risk