TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT01509404

Adverse event: CMV disease
Serious: yes
Organ System: Infections and infestations
Frequency: 3 affected / 20 at risk

Adverse event: Graft loss
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 20 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 9 affected / 20 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 20 at risk

Adverse event: BK infection
Serious: no
Organ System: Renal and urinary disorders
Frequency: 3 affected / 20 at risk

Adverse event: Acute rejection
Serious: no
Organ System: Renal and urinary disorders
Frequency: 2 affected / 20 at risk

Adverse event: CMV disease
Serious: yes
Organ System: Infections and infestations
Frequency: 4 affected / 20 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 10 affected / 20 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 20 at risk

Adverse event: BK infection
Serious: no
Organ System: Renal and urinary disorders
Frequency: 5 affected / 20 at risk

Adverse event: Candida infection
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 20 at risk

Adverse event: Acute rejection
Serious: no
Organ System: Renal and urinary disorders
Frequency: 6 affected / 20 at risk
Study: NCT01509586

Adverse event: Death
Serious: yes
Organ System: General disorders
Frequency: 3 affected / 626 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 93 affected / 626 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 79 affected / 626 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 68 affected / 626 at risk

Adverse event: mouth soreness
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 46 affected / 626 at risk

Adverse event: dizziness or lightheadnedness
Serious: no
Organ System: General disorders
Frequency: 54 affected / 626 at risk

Adverse event: Dry mouth
Serious: no
Organ System: General disorders
Frequency: 53 affected / 626 at risk

Adverse event: sore jaw
Serious: no
Organ System: General disorders
Frequency: 14 affected / 626 at risk

Adverse event: excessive salivation
Serious: no
Organ System: General disorders
Frequency: 29 affected / 626 at risk

Adverse event: Insomnia
Serious: no
Organ System: General disorders
Frequency: 66 affected / 626 at risk

Adverse event: Hiccups
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 44 affected / 626 at risk

Adverse event: burning in throat/mouth
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 59 affected / 626 at risk

Adverse event: other
Serious: no
Organ System: General disorders
Frequency: 338 affected / 626 at risk

Adverse event: Death
Serious: yes
Organ System: General disorders
Frequency: 3 affected / 610 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 82 affected / 610 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 93 affected / 610 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 51 affected / 610 at risk

Adverse event: mouth soreness
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 43 affected / 610 at risk

Adverse event: dizziness or lightheadnedness
Serious: no
Organ System: General disorders
Frequency: 61 affected / 610 at risk

Adverse event: Dry mouth
Serious: no
Organ System: General disorders
Frequency: 57 affected / 610 at risk

Adverse event: sore jaw
Serious: no
Organ System: General disorders
Frequency: 18 affected / 610 at risk

Adverse event: excessive salivation
Serious: no
Organ System: General disorders
Frequency: 15 affected / 610 at risk

Adverse event: Insomnia
Serious: no
Organ System: General disorders
Frequency: 70 affected / 610 at risk

Adverse event: Hiccups
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 21 affected / 610 at risk

Adverse event: burning in throat/mouth
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 21 affected / 610 at risk

Adverse event: other
Serious: no
Organ System: General disorders
Frequency: 332 affected / 610 at risk
Study: NCT01509625

Adverse event: Gastrointestinal disorders
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 18 affected / 263 at risk

Adverse event: Pain in inyection site
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 26 affected / 263 at risk

Adverse event: Musculoskeletal disorders
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 19 affected / 263 at risk

Adverse event: Hot flush
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 16 affected / 263 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 263 at risk

Adverse event: Weight increased
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 263 at risk

Adverse event: Vaginal infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 263 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 42 affected / 263 at risk
Study: NCT01510327

Adverse event: Gastritis erosive
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 22 at risk

Adverse event: Vascular pseudoaneurysm
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 22 at risk

Adverse event: Synovial cyst
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 22 at risk

Adverse event: Pulmonary embolism
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 22 at risk

Adverse event: Deep vein thrombosis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 22 at risk

Adverse event: Catheter site haematoma
Serious: no
Organ System: General disorders
Frequency: 4 affected / 22 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 22 at risk

Adverse event: Non-cardiac chest pain
Serious: no
Organ System: General disorders
Frequency: 2 affected / 22 at risk

Adverse event: Angina pectoris
Serious: no
Organ System: Cardiac disorders
Frequency: 3 affected / 22 at risk
Study: NCT01510457

Adverse event: Nausea
Serious: no
Organ System: General disorders
Frequency: 3 affected / 26 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 3 affected / 26 at risk

Adverse event: Trouble Sleeping
Serious: no
Organ System: General disorders
Frequency: 2 affected / 26 at risk

Adverse event: Constipation
Serious: no
Organ System: General disorders
Frequency: 2 affected / 26 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 2 affected / 26 at risk

Adverse event: Transient tachycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 26 at risk

Adverse event: Urinary retention
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 26 at risk
Study: NCT01510756

Adverse event: Brain abscess (aspergillus)
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 4 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 4 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 4 at risk

Adverse event: Amylase elevation
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 4 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 4 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 4 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 4 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 4 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 2 affected / 4 at risk

Adverse event: Hand foot syndrome
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 4 at risk

Adverse event: Haemorrhoids
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 4 at risk

Adverse event: Dysphonia
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 4 at risk

Adverse event: hyperbillirubinema
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 4 at risk

Adverse event: Lipase elevation
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 4 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 4 at risk

Adverse event: Myalgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 4 at risk

Adverse event: Polyuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 2 affected / 4 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 4 at risk

Adverse event: Squamous cell carcinoma
Serious: no
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 4 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 4 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 4 at risk
Study: NCT01511016

Adverse event: Hyperthyroidism
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 8 at risk

Adverse event: Weight decreased
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 9 at risk
Study: NCT01511055

Adverse event: Sneezing, spontaneous onset
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 27 at risk

Adverse event: Tingling sensation in mouth, palate and molars
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 27 at risk

Adverse event: Mild facial flusing
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 27 at risk

Adverse event: Paranasal sinus discomfort
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 27 at risk

Adverse event: Plugged ears
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 27 at risk

Adverse event: Strong taste in mouth
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 27 at risk

Adverse event: Cirumoral and Nasal Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 27 at risk

Adverse event: Migraine
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 27 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 27 at risk
Study: NCT01511068

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 2 at risk

Adverse event: Noseblood
Serious: no
Organ System: General disorders
Frequency: 1 affected / 2 at risk
Study: NCT01511081

Adverse event: Metastatic squamous cell carcinoma of the lung
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 9 at risk
Study: NCT01511445

Adverse event: Replacement of implant due to subsidence
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Cage subsidence led to symptoms; revised by removing cage and replacing with bone graft and a cervical plate
Frequency: 1 affected / 53 at risk

Adverse event: Debridement of abscess
Serious: yes
Organ System: Infections and infestations
Notes: The abscess was cleaned in a second surgery without cage removal
Frequency: 1 affected / 53 at risk

Adverse event: Aphasia
Serious: no
Organ System: Injury, poisoning and procedural complications
Notes: Difficulty swallowing in the immediate post-op period. All cases resolved completely as post-op swelling subsided.
Frequency: 9 affected / 53 at risk

Adverse event: Surgery at additional spinal level
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Surgery for development of new or persistent symptoms. More common at lower cervical spine levels.
Frequency: 6 affected / 53 at risk

Adverse event: Removal for restenosis
Serious: no
Organ System: Immune system disorders
Notes: Patient had undiagnosed Becherew's disease (ankylosing spondylitis), an exclusion criterion for the study. A bone spur regrew underneath the cage. The patient had a revision with bone graft and a cervical plate.
Frequency: 1 affected / 53 at risk

Adverse event: Replacement of implant due to subsidence
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Cage subsidence led to symptoms; revised by removing cage and replacing with bone graft and a cervical plate
Frequency: 1 affected / 51 at risk

Adverse event: Aphasia
Serious: no
Organ System: Injury, poisoning and procedural complications
Notes: Difficulty swallowing in the immediate post-op period. All cases resolved completely as post-op swelling subsided.
Frequency: 8 affected / 51 at risk

Adverse event: Surgery at additional spinal level
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Surgery for development of new or persistent symptoms. More common at lower cervical spine levels.
Frequency: 3 affected / 51 at risk
Study: NCT01511614

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 2 affected / 28 at risk

Adverse event: Lower back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 28 at risk

Adverse event: Elevated Blood Pressure
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 28 at risk

Adverse event: Shortness of Breath/Palpitations
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 28 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 2 affected / 32 at risk

Adverse event: Lower back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 32 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 1 affected / 32 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 32 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 1 affected / 32 at risk

Adverse event: Nausea
Serious: no
Organ System: General disorders
Frequency: 2 affected / 32 at risk

Adverse event: General Warmth
Serious: no
Organ System: General disorders
Notes: One particular participant reported an uncomfortable warm feeling in neck during tDCS in scanner.
Frequency: 1 affected / 32 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 1 affected / 33 at risk

Adverse event: Brief Psychotic Reaction
Serious: no
Organ System: Psychiatric disorders
Notes: Paranoia
Frequency: 1 affected / 33 at risk

Adverse event: Nausea
Serious: no
Organ System: General disorders
Frequency: 1 affected / 33 at risk
Study: NCT01511640

Adverse event: Chest pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: associated with injury sustained during excessive use of alcohol
Frequency: 1 affected / 12 at risk

Adverse event: nausea/vomiting
Serious: no
Organ System: Gastrointestinal disorders
Notes: associated with consumption of spoiled food
Frequency: 1 affected / 13 at risk
Study: NCT01511809

Adverse event: acute coronary stenosis
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 51 at risk

Adverse event: left basal pneumonia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 51 at risk

Adverse event: acute hepatitis
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 51 at risk

Adverse event: acute hepatitis
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 52 at risk

Adverse event: nephrolitiasis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 2 affected / 52 at risk

Adverse event: cholecystitis due to cholelithiasis
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 52 at risk

Adverse event: Hyperuricaemia
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 52 at risk

Adverse event: gross haematuria with proteinuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 2 affected / 52 at risk
Study: NCT01512160

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 4 affected / 22 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 22 at risk

Adverse event: Tooth infection
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 22 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 5 affected / 22 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 6 affected / 22 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 23 at risk

Adverse event: Blood bilirubin increased
Serious: no
Organ System: Investigations
Frequency: 2 affected / 23 at risk

Adverse event: Blood bilirubin unconjugated increased
Serious: no
Organ System: Investigations
Frequency: 2 affected / 23 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 8 affected / 23 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 23 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 23 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 22 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 22 at risk

Adverse event: Tooth infection
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 22 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 22 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 22 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 22 at risk

Adverse event: Tooth infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 23 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 23 at risk
Study: NCT01512225

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 10 affected / 45 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 45 at risk
Study: NCT01512667

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 13 at risk

Adverse event: Gastrooesophageal reflux disease
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 13 at risk

Adverse event: Toothache
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 13 at risk

Adverse event: Bronchitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 13 at risk

Adverse event: Eye injury
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 13 at risk

Adverse event: Fall
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 13 at risk

Adverse event: Hyperphosphataemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 13 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 13 at risk

Adverse event: Haematuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 13 at risk

Adverse event: Epistaxis
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 13 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 12 at risk

Adverse event: Urethritis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 12 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 12 at risk
Study: NCT01512693

Adverse event: Nasopharynigitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 8 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 9 at risk
Study: NCT01512849

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 12 at risk

Adverse event: Protein urine present
Serious: no
Organ System: Investigations
Frequency: 1 affected / 12 at risk

Adverse event: Pollakiuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 12 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 12 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 12 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 12 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 12 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 12 at risk

Adverse event: Blood creatin phosphokinase increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 12 at risk

Adverse event: Blood creatinine increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 12 at risk

Adverse event: Blood glucose increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 12 at risk