TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04358549

Adverse event: Osteomyelitis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 24 at risk

Adverse event: Staphylococcal infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 24 at risk

Adverse event: Basal ganglia haemorrhage
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 24 at risk

Adverse event: Blood lactate dehydrogenase increased
Serious: no
Organ System: Investigations
Frequency: 2 affected / 24 at risk

Adverse event: Gamma-glutamyltransferase increased
Serious: no
Organ System: Investigations
Frequency: 3 affected / 24 at risk

Adverse event: Inflammatory marker increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 24 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 24 at risk

Adverse event: Respiratory failure
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 24 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 24 at risk

Adverse event: Acute kidney injury
Serious: no
Organ System: Renal and urinary disorders
Frequency: 3 affected / 24 at risk

Adverse event: Necrosis
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 25 at risk

Adverse event: Clostridium difficile infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 25 at risk

Adverse event: Urinary tract infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 25 at risk

Adverse event: Failure to thrive
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 25 at risk

Adverse event: Inflammatory marker increased
Serious: no
Organ System: Investigations
Frequency: 4 affected / 25 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 25 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 25 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 25 at risk

Adverse event: Respiratory failure
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 25 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 25 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 25 at risk
Study: NCT04359680

Adverse event: Abdominal hernia
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 686 at risk

Adverse event: Drug-induced liver injury
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 686 at risk

Adverse event: Ankle fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 686 at risk

Adverse event: Myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 663 at risk

Adverse event: Syncope
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 663 at risk

Adverse event: Cholelithiasis
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 663 at risk

Adverse event: Epididymitis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 663 at risk

Adverse event: Lower limb fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 663 at risk

Adverse event: Uterine cancer
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 663 at risk
Study: NCT04359810

Adverse event: Cardiovascular event
Serious: yes
Organ System: Vascular disorders
Frequency: 16 affected / 147 at risk

Adverse event: Pulmonary adverse event
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 24 affected / 147 at risk

Adverse event: Renal/metabolic adverse event
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 7 affected / 147 at risk

Adverse event: Infectious adverse event
Serious: yes
Organ System: Infections and infestations
Frequency: 5 affected / 147 at risk

Adverse event: Hematologic adverse event
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 6 affected / 147 at risk

Adverse event: Inflammatory adverse event
Serious: yes
Organ System: Immune system disorders
Frequency: 1 affected / 147 at risk

Adverse event: Anemia, worsening
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 147 at risk

Adverse event: Urticaria
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 147 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 147 at risk

Adverse event: Transfusion-related circulatory overload
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 147 at risk

Adverse event: Cardiovascular event
Serious: yes
Organ System: Vascular disorders
Frequency: 12 affected / 72 at risk

Adverse event: Pulmonary adverse event
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 16 affected / 72 at risk

Adverse event: Renal/metabolic adverse event
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 5 affected / 72 at risk

Adverse event: Infectious adverse event
Serious: yes
Organ System: Infections and infestations
Frequency: 10 affected / 72 at risk

Adverse event: Gastrointestinal/hepatic adverse event
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 72 at risk

Adverse event: Anemia, worsening
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 72 at risk

Adverse event: Urticaria
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 72 at risk

Adverse event: Transfusion-related circulatory overload
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 72 at risk

Adverse event: Possible febrile non-hemolytic transfusion reaction
Serious: no
Organ System: General disorders
Frequency: 1 affected / 72 at risk
Study: NCT04359823

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Patient noticed a rash on the inside of her right elbow. It was one of the many locations where she applied the cream. The rash has since went away after avoiding application to that area for a few days. She continued to use cream on other areas.
Frequency: 1 affected / 17 at risk

Adverse event: Muscular weakness
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Patient emailed and said she "had muscle weakness ( felt like my legs were quivering) after standing in a sailboat to steer for 3 hours under stressful conditions and again after playing 4 hours of croquet in one day". Patient continued with study.
Frequency: 1 affected / 17 at risk

Adverse event: Elevated CK
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Subject's PCP has been monitoring her CK as a result of starting statin therapy. CK 664. PCP recommended continued participation in the study granted significant improvement of DSAP lesions and no symptoms or additional signs relevant to the therapy.
Frequency: 1 affected / 17 at risk
Study: NCT04360174

Adverse event: Congenital, familial and genetic disorders
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 5 at risk

Adverse event: Eye Disorders
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 5 at risk

Adverse event: Eye Disorders
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 4 at risk

Adverse event: Eye Disorders
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 5 at risk

Adverse event: Uncoded Terms
Serious: no
Organ System: Eye disorders
Notes: Uncoded terms in Cohort 3 consisted of 2 events of corneal edema in the Study Eye and an event of fixed and dilated pupil in the Study Eye
Frequency: 2 affected / 5 at risk

Adverse event: Investigations
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 5 at risk

Adverse event: Eye Disorders
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 5 at risk
Study: NCT04360551

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 12 at risk

Adverse event: Nasal congestion
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 12 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 12 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 12 at risk

Adverse event: Chest discomfort
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 12 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 12 at risk

Adverse event: Nasal congestion
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 12 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 12 at risk
Study: NCT04360824

Adverse event: Acute kidney injury
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 15 affected / 86 at risk

Adverse event: Arterial thrombosis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 86 at risk

Adverse event: Venous thrombosis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 6 affected / 86 at risk

Adverse event: Major bleeding
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 86 at risk

Adverse event: Minor bleeding
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 6 affected / 86 at risk

Adverse event: Acute kidney injury
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 11 affected / 87 at risk

Adverse event: Arterial thrombosis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 5 affected / 87 at risk

Adverse event: Venous thrombosis
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 7 affected / 87 at risk

Adverse event: Major bleeding
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 87 at risk

Adverse event: Minor bleeding
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 6 affected / 87 at risk
Study: NCT04362085

Adverse event: Hospitalisation
Serious: yes
Organ System: General disorders
Notes: Hospitalization
Frequency: 228 affected / 228 at risk

Adverse event: Laboratory confirmed SARS-CoV-2 infection
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 228 affected / 228 at risk

Adverse event: Hospitalisation
Serious: yes
Organ System: General disorders
Notes: Hospitalization
Frequency: 237 affected / 237 at risk

Adverse event: Laboratory confirmed SARS-CoV-2 infection
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 237 affected / 237 at risk
Study: NCT04362111

Adverse event: Acute respiratory distress syndrome
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Development of respiratory failure due to diffuse lung inflammation
Frequency: 9 affected / 15 at risk

Adverse event: Ischaemia
Serious: yes
Organ System: Vascular disorders
Notes: Evidence of ischemic injury to an extremity or internal organ or central nervous system
Frequency: 4 affected / 15 at risk

Adverse event: Venous thrombosis
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Deep venous thrombosis, with or without pulmonary embolism
Frequency: 4 affected / 15 at risk

Adverse event: Acute kidney injury
Serious: no
Organ System: Renal and urinary disorders
Notes: Development of acute kidney injury with azotemia and decreased urine output
Frequency: 7 affected / 15 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Total neutrophil count less than 1000/mm3
Frequency: 1 affected / 15 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Decrease in hemoglobin to less than 8.0 g/dL
Frequency: 14 affected / 15 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Decrease in platelets to less than 100,000/mm3
Frequency: 5 affected / 15 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: no
Organ System: Gastrointestinal disorders
Notes: Evidence of clinically significant GI bleed with documented GI blood loss and associated fall in hemoglobin
Frequency: 1 affected / 15 at risk

Adverse event: Acute respiratory distress syndrome
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Development of respiratory failure due to diffuse lung inflammation
Frequency: 7 affected / 15 at risk

Adverse event: Ischaemia
Serious: yes
Organ System: Vascular disorders
Notes: Evidence of ischemic injury to an extremity or internal organ or central nervous system
Frequency: 5 affected / 15 at risk

Adverse event: Venous thrombosis
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Deep venous thrombosis, with or without pulmonary embolism
Frequency: 3 affected / 15 at risk

Adverse event: Acute kidney injury
Serious: no
Organ System: Renal and urinary disorders
Notes: Development of acute kidney injury with azotemia and decreased urine output
Frequency: 6 affected / 15 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Decrease in hemoglobin to less than 8.0 g/dL
Frequency: 13 affected / 15 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Decrease in platelets to less than 100,000/mm3
Frequency: 5 affected / 15 at risk
Study: NCT04362670

Adverse event: Hiatus hernia
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 42 at risk

Adverse event: Eye Disorders
Serious: no
Organ System: Eye disorders
Frequency: 13 affected / 42 at risk

Adverse event: Fall
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 42 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 42 at risk

Adverse event: COVID-19 pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 41 at risk

Adverse event: Hip fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 41 at risk

Adverse event: Eye Disorders
Serious: no
Organ System: Eye disorders
Frequency: 11 affected / 41 at risk

Adverse event: Vertigo
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 41 at risk

Adverse event: COVID-19
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 41 at risk

Adverse event: Oral herpes
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 41 at risk

Adverse event: Ankle fracture
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 41 at risk

Adverse event: Angioedema
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 41 at risk

Adverse event: Eye Disorders
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 43 at risk

Adverse event: COVID-19
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 43 at risk

Adverse event: Candida infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 43 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 43 at risk

Adverse event: Eye Disorders
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 22 at risk
Study: NCT04364048

Adverse event: Muscular weakness
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 10 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 10 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 10 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 10 at risk

Adverse event: Blood alkaline phosphatase increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 10 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 10 at risk

Adverse event: Anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 10 at risk

Adverse event: Chills
Serious: no
Organ System: General disorders
Frequency: 1 affected / 10 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 10 at risk

Adverse event: Creatinine Increase
Serious: no
Organ System: Investigations
Frequency: 1 affected / 10 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 10 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 10 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 10 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 10 at risk

Adverse event: Hiccups
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 10 at risk

Adverse event: Hyperkalaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 10 at risk

Adverse event: Hypomagnesaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 10 at risk

Adverse event: Hypothyroidism
Serious: no
Organ System: Endocrine disorders
Frequency: 1 affected / 10 at risk

Adverse event: Infusion related reaction
Serious: no
Organ System: General disorders
Frequency: 1 affected / 10 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 10 at risk

Adverse event: Mucositis/Mouth Pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 10 at risk

Adverse event: Odynophagia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 10 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 10 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 5 affected / 10 at risk

Adverse event: Neuropathy peripheral
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 10 at risk
Study: NCT04364386

Adverse event: urine retention post extraction with forceps with infected opened perineal laceration
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 10 at risk
Study: NCT04364763

Adverse event: Cerebral infarction
Serious: yes
Organ System: Nervous system disorders
Notes: Acute right posterior cerebral infarct
Frequency: 1 affected / 28 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Pneumonia
Frequency: 1 affected / 28 at risk

Adverse event: Pulmonary mass
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Left lung mass
Frequency: 1 affected / 28 at risk

Adverse event: Erythema
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 2 affected / 28 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 28 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 28 at risk

Adverse event: Paraesthesia
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 2 at risk

Adverse event: Myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Notes: Myocardial infarction resulting in death
Frequency: 1 affected / 14 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 14 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 14 at risk

Adverse event: Onychomycosis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 14 at risk

Adverse event: Tinea cruris
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 14 at risk

Adverse event: Tachycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 14 at risk
Study: NCT04364867

Adverse event: Catheter Dislodgement
Serious: yes
Organ System: Product Issues
Frequency: 2 affected / 35 at risk
Study: NCT04364984

Adverse event: Hypotension
Serious: yes
Organ System: Vascular disorders
Notes: hypotension as less than 110 mm Hg
Frequency: 2 affected / 35 at risk

Adverse event: Hypotension
Serious: yes
Organ System: Vascular disorders
Notes: hypotension as less than 110 mm Hg
Frequency: 16 affected / 42 at risk

Adverse event: Hypotension
Serious: yes
Organ System: Vascular disorders
Notes: hypotension as less than 110 mm Hg
Frequency: 7 affected / 31 at risk
Study: NCT04365257

Adverse event: Hypotension
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 3 at risk

Adverse event: Hypoxia during the night
Serious: no
Organ System: General disorders
Frequency: 1 affected / 3 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 2 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 2 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 1 affected / 2 at risk

Adverse event: Micturition urgency
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 2 at risk
Study: NCT04365699

Adverse event: Nausea / Upset GI
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 10 at risk

Adverse event: Localized Skin Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 10 at risk