Study: NCT02714257

Adverse event: Fracture
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 25 affected / 569 at risk

Adverse event: Elective Joint Replacement
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 18 affected / 569 at risk

Adverse event: Other Surgery
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 14 affected / 569 at risk

Adverse event: Infection
Serious: yes
Organ System: Infections and infestations
Frequency: 20 affected / 569 at risk

Adverse event: Neoplasm
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 3 affected / 569 at risk

Adverse event: Atrial Fibrillation/Flutter
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 569 at risk

Adverse event: Cardiac failure
Serious: yes
Organ System: Cardiac disorders
Frequency: 7 affected / 569 at risk

Adverse event: Acute Coronary Syndrome / Myocardial Infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 5 affected / 569 at risk

Adverse event: Stroke / Transient Ischemic Attack / Intracranial Hemorrhage
Serious: yes
Organ System: Cardiac disorders
Frequency: 11 affected / 569 at risk

Adverse event: Fluid / Electrolyte Abnormality
Serious: yes
Organ System: General disorders
Frequency: 2 affected / 569 at risk

Adverse event: Dehydration
Serious: yes
Organ System: General disorders
Frequency: 2 affected / 569 at risk

Adverse event: Imbalance (syncope, dizziness, vertigo)
Serious: yes
Organ System: General disorders
Frequency: 3 affected / 569 at risk

Adverse event: Other
Serious: yes
Organ System: General disorders
Frequency: 51 affected / 569 at risk

Adverse event: Fracture
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 570 at risk

Adverse event: Elective Joint Replacement
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 570 at risk

Adverse event: Other Surgery
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 4 affected / 570 at risk

Adverse event: Infection
Serious: yes
Organ System: Infections and infestations
Frequency: 12 affected / 570 at risk

Adverse event: Neoplasm
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 2 affected / 570 at risk

Adverse event: Atrial Fibrillation/Flutter
Serious: yes
Organ System: Cardiac disorders
Frequency: 4 affected / 570 at risk

Adverse event: Cardiac failure
Serious: yes
Organ System: Cardiac disorders
Frequency: 3 affected / 570 at risk

Adverse event: Acute Coronary Syndrome / Myocardial Infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 570 at risk

Adverse event: Stroke / Transient Ischemic Attack / Intracranial Hemorrhage
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 570 at risk

Adverse event: Fluid / Electrolyte Abnormality
Serious: yes
Organ System: General disorders
Frequency: 3 affected / 570 at risk

Adverse event: Imbalance (syncope, dizziness, vertigo)
Serious: yes
Organ System: General disorders
Frequency: 6 affected / 570 at risk

Adverse event: Other
Serious: yes
Organ System: General disorders
Frequency: 37 affected / 570 at risk