Study: NCT02303990

Adverse event: Death
Serious: yes
Organ System: General disorders
Frequency: 8 affected / 59 at risk

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 59 at risk

Adverse event: Not Otherwise Specified
Serious: yes
Organ System: General disorders
Frequency: 6 affected / 59 at risk

Adverse event: Dehydration
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 59 at risk

Adverse event: Dizziness
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Fatigue
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Pyrexia
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Hypotension
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 59 at risk

Adverse event: Nausea
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Respiratory failure
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 59 at risk

Adverse event: Sepsis
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Small intestinal obstruction
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 59 at risk

Adverse event: Not otherwise specified
Serious: no
Organ System: General disorders
Frequency: 24 affected / 59 at risk

Adverse event: Abdominal distension
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: General disorders
Frequency: 11 affected / 59 at risk

Adverse event: Blood alkaline phosphatase increased
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Alopecia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Anaemia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: General disorders
Frequency: 21 affected / 59 at risk

Adverse event: Anxiety
Serious: no
Organ System: General disorders
Frequency: 5 affected / 59 at risk

Adverse event: Arthralgia
Serious: no
Organ System: General disorders
Frequency: 2 affected / 59 at risk

Adverse event: Anrhritis
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Ataxia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Back pain
Serious: no
Organ System: General disorders
Frequency: 5 affected / 59 at risk

Adverse event: Abdominal distension
Serious: no
Organ System: General disorders
Frequency: 7 affected / 59 at risk

Adverse event: Vision blurred
Serious: no
Organ System: General disorders
Frequency: 2 affected / 59 at risk

Adverse event: Bone pain
Serious: no
Organ System: General disorders
Frequency: 3 affected / 59 at risk

Adverse event: Bronchospasm
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Contusion
Serious: no
Organ System: General disorders
Frequency: 2 affected / 59 at risk

Adverse event: Musculoskeletal chest pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Chills
Serious: no
Organ System: General disorders
Frequency: 4 affected / 59 at risk

Adverse event: Colitis
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Confusional state
Serious: no
Organ System: General disorders
Frequency: 5 affected / 59 at risk

Adverse event: Conjunctivitis
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Constipation
Serious: no
Organ System: General disorders
Frequency: 13 affected / 59 at risk

Adverse event: Cough
Serious: no
Organ System: General disorders
Frequency: 15 affected / 59 at risk

Adverse event: Dehydration
Serious: no
Organ System: General disorders
Frequency: 5 affected / 59 at risk

Adverse event: Depressed level of consciousness
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Depression
Serious: no
Organ System: General disorders
Frequency: 8 affected / 59 at risk

Adverse event: Radiation skin injury
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: General disorders
Frequency: 6 affected / 59 at risk

Adverse event: Dizziness
Serious: no
Organ System: General disorders
Frequency: 5 affected / 59 at risk

Adverse event: Dry mouth
Serious: no
Organ System: General disorders
Frequency: 2 affected / 59 at risk

Adverse event: Dysgeusia
Serious: no
Organ System: General disorders
Frequency: 2 affected / 59 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: General disorders
Frequency: 8 affected / 59 at risk

Adverse event: Dysphagia
Serious: no
Organ System: General disorders
Frequency: 3 affected / 59 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: General disorders
Frequency: 9 affected / 59 at risk

Adverse event: Oedema peripheral
Serious: no
Organ System: General disorders
Frequency: 6 affected / 59 at risk

Adverse event: Erythema multiforme
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Esphagitis
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Extraocular muscle disorder
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Facial paresis
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Fall
Serious: no
Organ System: General disorders
Frequency: 3 affected / 59 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 28 affected / 59 at risk

Adverse event: Anal incontinence
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 6 affected / 59 at risk

Adverse event: Flank pain
Serious: no
Organ System: General disorders
Frequency: 2 affected / 59 at risk

Adverse event: Flatulence
Serious: no
Organ System: General disorders
Frequency: 2 affected / 59 at risk

Adverse event: Influenza like illness
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Flushing
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Gastritis
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Gastrooesophageal reflux disease
Serious: no
Organ System: General disorders
Frequency: 3 affected / 59 at risk

Adverse event: Muscular weakness
Serious: no
Organ System: General disorders
Frequency: 2 affected / 59 at risk

Adverse event: Palmar-plantar erythrodysaesthesia syndrome
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Headache
Serious: no
Organ System: General disorders
Frequency: 6 affected / 59 at risk

Adverse event: Haematuria
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Dysphonia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Hot flush
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Hypercalcaemia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Hypoxia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Ileus
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Insomnia
Serious: no
Organ System: General disorders
Frequency: 6 affected / 59 at risk

Adverse event: Localised oedema
Serious: no
Organ System: General disorders
Frequency: 3 affected / 59 at risk

Adverse event: Lymphocyte count decreased
Serious: no
Organ System: General disorders
Frequency: 2 affected / 59 at risk

Adverse event: Muscular weakness
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Myalgia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Nausea
Serious: no
Organ System: General disorders
Frequency: 22 affected / 59 at risk

Adverse event: Localised oedema
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Neck pain
Serious: no
Organ System: General disorders
Frequency: 3 affected / 59 at risk

Adverse event: Non-cardiac chest pain
Serious: no
Organ System: General disorders
Frequency: 2 affected / 59 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Frequency: 3 affected / 59 at risk

Adverse event: Pain in extremity
Serious: no
Organ System: General disorders
Frequency: 3 affected / 59 at risk

Adverse event: Palpitations
Serious: no
Organ System: General disorders
Frequency: 3 affected / 59 at risk

Adverse event: Paraesthesia
Serious: no
Organ System: General disorders
Frequency: 2 affected / 59 at risk

Adverse event: Pelvic pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Peripheral sensory neuropathy
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Pleural effusion
Serious: no
Organ System: General disorders
Frequency: 4 affected / 59 at risk

Adverse event: Portal vein thrombosis
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Pruritus
Serious: no
Organ System: General disorders
Frequency: 5 affected / 59 at risk

Adverse event: Pain of skin
Serious: no
Organ System: General disorders
Frequency: 2 affected / 59 at risk

Adverse event: Sepsis
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Sinusititis
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: General disorders
Frequency: 5 affected / 59 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: General disorders
Frequency: 2 affected / 59 at risk

Adverse event: Dysphonia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk

Adverse event: Vomiting
Serious: no
Organ System: General disorders
Frequency: 8 affected / 59 at risk

Adverse event: Weight decreased
Serious: no
Organ System: General disorders
Frequency: 3 affected / 59 at risk

Adverse event: Wheezing
Serious: no
Organ System: General disorders
Frequency: 1 affected / 59 at risk