TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT04803396

Adverse event: Limb discomfort
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 8 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 8 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 6 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 6 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 6 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 6 at risk
Study: NCT04806594

Adverse event: mild foot contusion).
Serious: no
Organ System: General disorders
Frequency: 1 affected / 40 at risk
Study: NCT04811339

Adverse event: Abdominal distension
Serious: no
Organ System: Gastrointestinal disorders
Notes: The patients felt bloated or let the coordinators know they had abdominal discomfort
Frequency: 3 affected / 9 at risk
Study: NCT04820322

Adverse event: Infection
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Deemed to be of moderate severity and not related to the investigational product by the qualified investigator.
Frequency: 1 affected / 16 at risk
Study: NCT04821245

Adverse event: Warmth around adductor canal catheter during MRI
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: As described above - mild, vague warmth around catheter at start of MRI, which was subsequently cancelled. The warmth resolved quickly and the patient was not harmed.
Frequency: 1 affected / 13 at risk
Study: NCT04827394

Adverse event: Elevated temperature
Serious: no
Organ System: Pregnancy, puerperium and perinatal conditions
Frequency: 2 affected / 25 at risk

Adverse event: Elevated temperature
Serious: no
Organ System: Pregnancy, puerperium and perinatal conditions
Frequency: 1 affected / 25 at risk
Study: NCT04838054

Adverse event: Bitterness in the mouth
Serious: no
Organ System: Product Issues
Frequency: 1 affected / 29 at risk

Adverse event: Unrelated injury
Serious: no
Organ System: Social circumstances
Notes: Patient sustained knee injury through a fall in the bathroom and was unable to complete the study
Frequency: 1 affected / 29 at risk

Adverse event: Scheduling Issues
Serious: no
Organ System: Social circumstances
Frequency: 1 affected / 29 at risk

Adverse event: Scheduling Issues
Serious: no
Organ System: Social circumstances
Frequency: 1 affected / 28 at risk
Study: NCT04843007

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 50 affected / 198 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 177 affected / 198 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 49 affected / 198 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 57 affected / 198 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 20 affected / 198 at risk

Adverse event: Alanine aminotransferase increased
Serious: no
Organ System: Investigations
Frequency: 20 affected / 198 at risk

Adverse event: Aspartate aminotransferase increased
Serious: no
Organ System: Investigations
Frequency: 12 affected / 198 at risk

Adverse event: Creatinine renal clearance decreased
Serious: no
Organ System: Investigations
Frequency: 48 affected / 198 at risk

Adverse event: Renal disorder
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 198 at risk

Adverse event: Drug intolerance
Serious: no
Organ System: General disorders
Frequency: 1 affected / 198 at risk
Study: NCT04854642

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 33 at risk

Adverse event: Presyncope
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 33 at risk

Adverse event: Toothache
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 33 at risk

Adverse event: Neck pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 33 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 3 affected / 35 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 35 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 35 at risk

Adverse event: SARS-CoV-2 test positive
Serious: no
Organ System: Investigations
Frequency: 1 affected / 35 at risk
Study: NCT04854707

Adverse event: Injection site pain
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Injection site pain was classified as skin and subcutaneous tissue disorders and included redness, pain, bruising and irritation without differentiation.
Frequency: 657 affected / 5484 at risk
Study: NCT04863807

Adverse event: ICU admission for respiratory complication
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 66 affected / 325 at risk

Adverse event: Intubation & Mechanical Ventilation
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 30 affected / 325 at risk

Adverse event: Any lung complication
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 110 affected / 325 at risk

Adverse event: ICU admission for respiratory complication
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 26 at risk

Adverse event: Intubation & Mechanical Ventilation
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 26 at risk

Adverse event: Any lung complication
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 10 affected / 26 at risk

Adverse event: ICU admission for respiratory complication
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 7 affected / 38 at risk

Adverse event: Intubation & Mechanical Ventilation
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 38 at risk

Adverse event: Any lung complication
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 13 affected / 38 at risk
Study: NCT04864691

Adverse event: Serious Adverse Event
Serious: yes
Organ System: Vascular disorders
Frequency: 9 affected / 148 at risk
Study: NCT04866290

Adverse event: Tumour rupture
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 105 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 89 affected / 105 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 28 affected / 105 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 19 affected / 105 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 17 affected / 105 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 4 affected / 105 at risk

Adverse event: Abscess
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 105 at risk

Adverse event: Liver abscess
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 105 at risk

Adverse event: Overdose
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 105 at risk

Adverse event: Blood bilirubin increased
Serious: no
Organ System: Investigations
Frequency: 12 affected / 105 at risk

Adverse event: Hepatic enzyme increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 105 at risk

Adverse event: Transaminases increased
Serious: no
Organ System: Investigations
Frequency: 10 affected / 105 at risk

Adverse event: White blood cell count increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 105 at risk
Study: NCT04870138

Adverse event: Blood pressure increased
Serious: no
Organ System: Investigations
Frequency: 2 affected / 5 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 5 at risk

Adverse event: Dysuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 2 affected / 5 at risk

Adverse event: Glycosuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 5 at risk

Adverse event: Urethral discharge
Serious: no
Organ System: Renal and urinary disorders
Frequency: 3 affected / 5 at risk

Adverse event: Urethritis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 5 at risk

Adverse event: Myalgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 5 at risk

Adverse event: Dysuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 2 affected / 5 at risk

Adverse event: Urethral discharge
Serious: no
Organ System: Renal and urinary disorders
Frequency: 5 affected / 5 at risk

Adverse event: Irritation or Itching
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 5 at risk

Adverse event: Upper-airway cough syndrome
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 5 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 6 at risk

Adverse event: Instillation site pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 6 at risk

Adverse event: Blood pressure increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Paraesthesia
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 6 at risk

Adverse event: Dysuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 6 at risk

Adverse event: Haematuria
Serious: no
Organ System: Renal and urinary disorders
Frequency: 1 affected / 6 at risk

Adverse event: Urethral discharge
Serious: no
Organ System: Renal and urinary disorders
Frequency: 5 affected / 6 at risk

Adverse event: Irritation or Itching
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 2 affected / 6 at risk
Study: NCT04876118

Adverse event: Urinary tract infection
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 97 at risk

Adverse event: Food poisoning
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 97 at risk

Adverse event: Bronchitis
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 97 at risk

Adverse event: Atypical lump of cells in left breast
Serious: yes
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 97 at risk

Adverse event: Pyrexia
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 97 at risk

Adverse event: Reaction post COVID-19 booster
Serious: no
Organ System: General disorders
Frequency: 1 affected / 97 at risk

Adverse event: Foot fracture
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 97 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 97 at risk

Adverse event: Right arm fracture
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 97 at risk

Adverse event: COVID-19
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 97 at risk

Adverse event: Herpes Zoster (Shingles)
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 97 at risk

Adverse event: Hyperpigmentation
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 3 affected / 97 at risk

Adverse event: Contour irregularity
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 97 at risk
Study: NCT04881942

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 32 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 32 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 32 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 32 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 32 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 32 at risk

Adverse event: Skin abrasion
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 32 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 32 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 32 at risk

Adverse event: Oral discomfort
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 32 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 32 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Coughing
Frequency: 1 affected / 3 at risk
Study: NCT04883060

Adverse event: Incorrect Burr Hole Placement
Serious: no
Organ System: Surgical and medical procedures
Notes: Burr hole was not between 3 and 4 cm away from anatomical midline
Frequency: 3 affected / 40 at risk

Adverse event: Ventricle Catheter Misplacement
Serious: no
Organ System: Surgical and medical procedures
Notes: Catheter tip entered the parenchyma at the level of gyrus fasciolaris
Frequency: 1 affected / 40 at risk
Study: NCT04886479

Adverse event: Dizziness
Serious: no
Organ System: Eye disorders
Notes: Transitional feeling of light-headedness during confocal microscopy. Unrelated to study, as neither DDH Lens nor DDSH Lens were worn at time of event.
Frequency: 1 affected / 9 at risk
Study: NCT04891406

Adverse event: Thrombophlebitis
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 22 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 22 at risk

Adverse event: Hiccups
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 22 at risk

Adverse event: Aphthous ulcer
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 22 at risk

Adverse event: Pruritus
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 23 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 22 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 22 at risk

Adverse event: Epistaxis
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 22 at risk
Study: NCT04891874

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 9 affected / 38 at risk

Adverse event: Abdominal distension
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 38 at risk

Adverse event: Dyspepsea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 38 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 38 at risk

Adverse event: Liver injury
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 2 affected / 38 at risk

Adverse event: Myelosuppression
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 38 at risk
Study: NCT04897737

Adverse event: Intimate Partner Violence
Serious: no
Organ System: Psychiatric disorders
Notes: Partner yelling and conflict after testing
Frequency: 1 affected / 53 at risk
Study: NCT04898166

Adverse event: 87 male and female participants death
Serious: yes
Organ System: Infections and infestations
Frequency: 87 affected / 300 at risk

Adverse event: Male and female participants on ventilator
Serious: yes
Organ System: Infections and infestations
Frequency: 56 affected / 300 at risk

Adverse event: Male and female participants on oxygen mask/bag
Serious: yes
Organ System: Infections and infestations
Frequency: 69 affected / 300 at risk

Adverse event: Male and female participants on nasal cannula
Serious: yes
Organ System: Infections and infestations
Frequency: 88 affected / 300 at risk
Study: NCT04902950

Adverse event: Drain size
Serious: no
Organ System: Surgical and medical procedures
Notes: Error in drain size; 19" instead of required 15".
Frequency: 4 affected / 4 at risk

Adverse event: Error in number of sponges
Serious: no
Organ System: Surgical and medical procedures
Notes: Used less than 3 required sponges that were used to administer the interventional product vs saline.
Frequency: 4 affected / 4 at risk

Adverse event: Drain output
Serious: no
Organ System: Surgical and medical procedures
Notes: Error in documentation.
Frequency: 3 affected / 4 at risk

Adverse event: Drain size
Serious: no
Organ System: Surgical and medical procedures
Notes: Error in drain size; 19" instead of required 15".
Frequency: 1 affected / 5 at risk

Adverse event: Error in number of sponges
Serious: no
Organ System: Surgical and medical procedures
Notes: Used less than 3 required sponges that were used to administer the interventional product vs saline.
Frequency: 2 affected / 5 at risk

Adverse event: Drain output
Serious: no
Organ System: Surgical and medical procedures
Notes: Error in documentation.
Frequency: 1 affected / 5 at risk
Study: NCT04910165

Adverse event: Vomiting
Serious: no
Organ System: General disorders
Frequency: 4 affected / 50 at risk
Study: NCT04917588

Adverse event: Application site pain
Serious: no
Organ System: General disorders
Notes: This event is related with the context of an injection site reaction
Frequency: 26 affected / 57 at risk

Adverse event: Injection site bruising
Serious: no
Organ System: General disorders
Notes: Injection site reaction
Frequency: 17 affected / 57 at risk

Adverse event: Injection site swelling
Serious: no
Organ System: General disorders
Notes: Injection site reaction
Frequency: 18 affected / 57 at risk

Adverse event: COVID 19
Serious: no
Organ System: Infections and infestations
Frequency: 11 affected / 57 at risk

Adverse event: Depression
Serious: yes
Organ System: Psychiatric disorders
Notes: Worsening of Depression
Frequency: 1 affected / 57 at risk

Adverse event: Application site pain
Serious: no
Organ System: General disorders
Notes: This event is related with the context of an injection site reaction
Frequency: 21 affected / 57 at risk

Adverse event: Injection site bruising
Serious: no
Organ System: General disorders
Notes: Injection site reaction
Frequency: 16 affected / 57 at risk

Adverse event: Injection site swelling
Serious: no
Organ System: General disorders
Notes: Injection site reaction
Frequency: 16 affected / 57 at risk

Adverse event: COVID 19
Serious: no
Organ System: Infections and infestations
Frequency: 7 affected / 57 at risk
Study: NCT04917757

Adverse event: MACE
Serious: yes
Organ System: Cardiac disorders
Notes: major adverse cardiovascular events (MACE): myocardial infarction or coronary revascularisation (either bypass surgery or percutaneous intervention), stroke, or cardiovascular-related death
Frequency: 145 affected / 1892 at risk

Adverse event: Dylipidemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 724 affected / 2002 at risk

Adverse event: MACE
Serious: yes
Organ System: Cardiac disorders
Notes: major adverse cardiovascular events (MACE): myocardial infarction or coronary revascularisation (either bypass surgery or percutaneous intervention), stroke, or cardiovascular-related death
Frequency: 130 affected / 1208 at risk

Adverse event: Dylipidemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 547 affected / 1250 at risk

Adverse event: MACE
Serious: yes
Organ System: Cardiac disorders
Notes: major adverse cardiovascular events (MACE): myocardial infarction or coronary revascularisation (either bypass surgery or percutaneous intervention), stroke, or cardiovascular-related death
Frequency: 22 affected / 225 at risk

Adverse event: Dylipidemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 123 affected / 232 at risk
Study: NCT04919161

Adverse event: Acute Ankle Sprain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 16 at risk

Adverse event: Flare-up of pre-existing orthopedic condition
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 16 at risk
Study: NCT04919317

Adverse event: Wound complications
Serious: no
Organ System: Surgical and medical procedures
Notes: Assessment of wound complications during any postoperative clinic visit
Frequency: 7 affected / 26 at risk

Adverse event: Wound complications
Serious: no
Organ System: Surgical and medical procedures
Notes: Assessment of wound complications during any postoperative clinic visit
Frequency: 8 affected / 25 at risk
Study: NCT04943159

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 1 affected / 3 at risk
Study: NCT04949802

Adverse event: COVID 19
Serious: yes
Organ System: Infections and infestations
Notes: Hospitalization due to COVID 19, not related to study device
Frequency: 3 affected / 15 at risk

Adverse event: Cystoid macular oedema
Serious: no
Organ System: Eye disorders
Notes: not related to study device
Frequency: 1 affected / 15 at risk

Adverse event: Optic ischaemic neuropathy
Serious: no
Organ System: Eye disorders
Notes: not related to study device
Frequency: 1 affected / 15 at risk

Adverse event: BCVA loss >= 2 lines
Serious: no
Organ System: Eye disorders
Notes: not related to study device
Frequency: 2 affected / 15 at risk

Adverse event: Visual Field progression, MD loss >=2.5dB
Serious: no
Organ System: Eye disorders
Notes: not related to study device
Frequency: 1 affected / 15 at risk
Study: NCT04957498

Adverse event: Hospitalisation
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 20 at risk

Adverse event: Hospitalisation
Serious: yes
Organ System: Psychiatric disorders
Frequency: 4 affected / 20 at risk