Study: NCT01856933

Adverse event: eye disorder/ vision changes
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: H/A
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Hypermagnesaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Hypokalaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Intratumoral hemorrhage
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Nausea
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Thrombocytopenia
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 6 at risk

Adverse event: Seizure
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Urinary tract infection
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: White blood cell count
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Confusional state
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: muscle weakness/weakness general
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 6 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Facial paresis
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: CD4 Lymph count
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 6 at risk

Adverse event: Lymphopenia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Decreased appetite
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Syncope
Serious: yes
Organ System: Investigations
Frequency: 2 affected / 6 at risk

Adverse event: Pain
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: perforation-sigmoid
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Blood cholesterol
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Blood creatinine
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Hyperglycaemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: hypoalbumin
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Troponin
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: AKI
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Alopecia
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Alanine aminotransferase
Serious: no
Organ System: Investigations
Frequency: 2 affected / 6 at risk

Adverse event: Aspartate aminotransferase
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Anaemia
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: edema, lower leg
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: eye disorder/ vision changes
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Fatigue
Serious: no
Organ System: Investigations
Frequency: 2 affected / 6 at risk

Adverse event: H/A
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Hypermagnesaemia
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Hypokalaemia
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Hyponatraemia
Serious: no
Organ System: Investigations
Frequency: 2 affected / 6 at risk

Adverse event: Infection/shingles/thrush
Serious: no
Organ System: Investigations
Frequency: 2 affected / 6 at risk

Adverse event: Nausea
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Neutrophil count
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Investigations
Frequency: 2 affected / 6 at risk

Adverse event: Vomiting
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: rash- torso
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: parathesia/neuropathy
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: rash- papular
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Urinary incontinence
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: right ankle swelling
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: White blood cell count
Serious: no
Organ System: Investigations
Frequency: 3 affected / 6 at risk

Adverse event: Cerebral haematoma
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: Lymphopenia
Serious: no
Organ System: Investigations
Frequency: 2 affected / 6 at risk

Adverse event: Aphasia
Serious: no
Organ System: Investigations
Frequency: 2 affected / 6 at risk

Adverse event: Gait disturbance
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: cognitive disturbance/impairment
Serious: no
Organ System: Investigations
Frequency: 2 affected / 6 at risk

Adverse event: dysgeusia (taste)
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk

Adverse event: pain- left calf/leg
Serious: no
Organ System: Investigations
Frequency: 1 affected / 6 at risk