Study: NCT01696435

Adverse event: Major cardiovascular event
Serious: yes
Organ System: Vascular disorders
Frequency: 144 affected / 4573 at risk

Adverse event: Invasive cancer of any type
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 281 affected / 4573 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 111 affected / 4573 at risk

Adverse event: Hypercalcaemia
Serious: yes
Organ System: Endocrine disorders
Frequency: 47 affected / 4573 at risk

Adverse event: Hyperparathyroidism or parathyroid condition
Serious: no
Organ System: Endocrine disorders
Frequency: 19 affected / 4573 at risk

Adverse event: Nephrolithiasis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 172 affected / 4573 at risk

Adverse event: Renal failure
Serious: no
Organ System: Renal and urinary disorders
Frequency: 27 affected / 4573 at risk

Adverse event: Haematuria
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Blood in urine
Frequency: 319 affected / 4573 at risk

Adverse event: Easy bruising
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1167 affected / 4573 at risk

Adverse event: Frequent nosebleeds
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 159 affected / 4573 at risk

Adverse event: Stomach upset or pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1594 affected / 4573 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1105 affected / 4573 at risk

Adverse event: Major cardiovascular event
Serious: yes
Organ System: Vascular disorders
Frequency: 129 affected / 4563 at risk

Adverse event: Invasive cancer of any type
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 301 affected / 4563 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 133 affected / 4563 at risk

Adverse event: Hypercalcaemia
Serious: yes
Organ System: Endocrine disorders
Frequency: 49 affected / 4563 at risk

Adverse event: Completed suicide
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 4563 at risk

Adverse event: Hyperparathyroidism or parathyroid condition
Serious: no
Organ System: Endocrine disorders
Frequency: 17 affected / 4563 at risk

Adverse event: Nephrolithiasis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 131 affected / 4563 at risk

Adverse event: Renal failure
Serious: no
Organ System: Renal and urinary disorders
Frequency: 28 affected / 4563 at risk

Adverse event: Haematuria
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Blood in urine
Frequency: 293 affected / 4563 at risk

Adverse event: Easy bruising
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1124 affected / 4563 at risk

Adverse event: Frequent nosebleeds
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 158 affected / 4563 at risk

Adverse event: Stomach upset or pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1616 affected / 4563 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1169 affected / 4563 at risk

Adverse event: Major cardiovascular event
Serious: yes
Organ System: Vascular disorders
Frequency: 126 affected / 4609 at risk

Adverse event: Invasive cancer of any type
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 291 affected / 4609 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 135 affected / 4609 at risk

Adverse event: Hypercalcaemia
Serious: yes
Organ System: Endocrine disorders
Frequency: 53 affected / 4609 at risk

Adverse event: Completed suicide
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 4609 at risk

Adverse event: Hyperparathyroidism or parathyroid condition
Serious: no
Organ System: Endocrine disorders
Frequency: 27 affected / 4609 at risk

Adverse event: Nephrolithiasis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 163 affected / 4609 at risk

Adverse event: Renal failure
Serious: no
Organ System: Renal and urinary disorders
Frequency: 29 affected / 4609 at risk

Adverse event: Haematuria
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Blood in urine
Frequency: 318 affected / 4609 at risk

Adverse event: Easy bruising
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1141 affected / 4609 at risk

Adverse event: Frequent nosebleeds
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 163 affected / 4609 at risk

Adverse event: Stomach upset or pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1625 affected / 4609 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1184 affected / 4609 at risk

Adverse event: Major cardiovascular event
Serious: yes
Organ System: Vascular disorders
Frequency: 120 affected / 4608 at risk

Adverse event: Invasive cancer of any type
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 312 affected / 4608 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 107 affected / 4608 at risk

Adverse event: Hypercalcaemia
Serious: yes
Organ System: Endocrine disorders
Frequency: 42 affected / 4608 at risk

Adverse event: Completed suicide
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 4608 at risk

Adverse event: Hyperparathyroidism or parathyroid condition
Serious: no
Organ System: Endocrine disorders
Frequency: 10 affected / 4608 at risk

Adverse event: Nephrolithiasis
Serious: no
Organ System: Renal and urinary disorders
Frequency: 158 affected / 4608 at risk

Adverse event: Renal failure
Serious: no
Organ System: Renal and urinary disorders
Frequency: 19 affected / 4608 at risk

Adverse event: Haematuria
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Blood in urine
Frequency: 333 affected / 4608 at risk

Adverse event: Easy bruising
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1152 affected / 4608 at risk

Adverse event: Frequent nosebleeds
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 159 affected / 4608 at risk

Adverse event: Stomach upset or pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1615 affected / 4608 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1124 affected / 4608 at risk