Study: NCT02054338

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 16 affected / 495 at risk

Adverse event: Febrile neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 17 affected / 495 at risk

Adverse event: Leukopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 7 affected / 495 at risk

Adverse event: Neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 54 affected / 495 at risk

Adverse event: Thrombocytopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 12 affected / 495 at risk

Adverse event: Atrial fibrillation
Serious: yes
Organ System: Cardiac disorders
Notes: Drug related
Frequency: 3 affected / 495 at risk

Adverse event: Supraventricular tachycardia
Serious: yes
Organ System: Cardiac disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Ventricular dysfunction
Serious: yes
Organ System: Cardiac disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Inappropriate antidiuretic hormone secretion
Serious: yes
Organ System: Endocrine disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Abdominal pain
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 19 affected / 495 at risk

Adverse event: Abdominal pain upper
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 2 affected / 495 at risk

Adverse event: Anal inflammation
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Constipation
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 28 affected / 495 at risk

Adverse event: Diarrhoea
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 19 affected / 495 at risk

Adverse event: Dysphagia
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 2 affected / 495 at risk

Adverse event: Enterocolitis
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 2 affected / 495 at risk

Adverse event: Ileus
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 17 affected / 495 at risk

Adverse event: Impaired gastric emptying
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Intestinal obstruction
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 2 affected / 495 at risk

Adverse event: Nausea
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 11 affected / 495 at risk

Adverse event: Odynophagia
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Stomatitis
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 6 affected / 495 at risk

Adverse event: Vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 16 affected / 495 at risk

Adverse event: Asthenia
Serious: yes
Organ System: General disorders
Notes: Drug related
Frequency: 2 affected / 495 at risk

Adverse event: Chest pain
Serious: yes
Organ System: General disorders
Notes: Drug related
Frequency: 3 affected / 495 at risk

Adverse event: Condition aggravated
Serious: yes
Organ System: General disorders
Notes: Drug related
Frequency: 5 affected / 495 at risk

Adverse event: Pyrexia
Serious: yes
Organ System: General disorders
Notes: Drug related
Frequency: 11 affected / 495 at risk

Adverse event: Injection site reaction
Serious: yes
Organ System: General disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Hepatic function abnormal
Serious: yes
Organ System: Hepatobiliary disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Hyperbilirubinaemia
Serious: yes
Organ System: Hepatobiliary disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Hypersensitivity
Serious: yes
Organ System: Immune system disorders
Notes: Drug related
Frequency: 2 affected / 495 at risk

Adverse event: Catheter-related infection
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 5 affected / 495 at risk

Adverse event: Cellulitis
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 2 affected / 495 at risk

Adverse event: Erysipelas
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 2 affected / 495 at risk

Adverse event: Gastroenteritis
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Neutropenic infection
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 15 affected / 495 at risk

Adverse event: Neutropenic sepsis
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Oral candidiasis
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Orophrayngeal candidiasis
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 10 affected / 495 at risk

Adverse event: Pyelonephritis
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Sepsis
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 2 affected / 495 at risk

Adverse event: Septic shock
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 4 affected / 495 at risk

Adverse event: Soft tissue infection
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Urinary tract infection
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 3 affected / 495 at risk

Adverse event: Alanine aminotransferase increased
Serious: yes
Organ System: Investigations
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Aspartate aminotransferase increased
Serious: yes
Organ System: Investigations
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Blood creatinine increased
Serious: yes
Organ System: Investigations
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Transaminases increased
Serious: yes
Organ System: Investigations
Notes: Drug related
Frequency: 2 affected / 495 at risk

Adverse event: Decreased appetite
Serious: yes
Organ System: Metabolism and nutrition disorders
Notes: Drug related
Frequency: 5 affected / 495 at risk

Adverse event: Dehydration
Serious: yes
Organ System: Metabolism and nutrition disorders
Notes: Drug related
Frequency: 11 affected / 495 at risk

Adverse event: Hypercalcaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Hyperglycaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Notes: Drug related
Frequency: 4 affected / 495 at risk

Adverse event: Hypocalcaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Notes: Drug related
Frequency: 2 affected / 495 at risk

Adverse event: Hypokalaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Notes: Drug related
Frequency: 11 affected / 495 at risk

Adverse event: Hyponatraemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Notes: Drug related
Frequency: 13 affected / 495 at risk

Adverse event: Hypovolaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Bone pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 2 affected / 495 at risk

Adverse event: Muscular weakness
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Musculoskeletal pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Myalgia
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Neck pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Pain in extremity
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Pain in jaw
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Tumour pain
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Encephalopathy
Serious: yes
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Headache
Serious: yes
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Paraesthesia
Serious: yes
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 2 affected / 495 at risk

Adverse event: Posterior reversible encephalopathy syndrome
Serious: yes
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Syncope
Serious: yes
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Alveolitis
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 8 affected / 495 at risk

Adverse event: Interstitial lung disease
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Lung disorder
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 2 affected / 495 at risk

Adverse event: Pulmonary embolism
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 6 affected / 495 at risk

Adverse event: Pulmonary ooedema
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Respiratory failure
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 5 affected / 495 at risk

Adverse event: Rash
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Skin ulcer
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Circulatory collapse
Serious: yes
Organ System: Vascular disorders
Notes: Drug related
Frequency: 2 affected / 495 at risk

Adverse event: Hypotension
Serious: yes
Organ System: Vascular disorders
Notes: Drug related
Frequency: 4 affected / 495 at risk

Adverse event: Peripheral venous disease
Serious: yes
Organ System: Vascular disorders
Notes: Drug related
Frequency: 1 affected / 495 at risk

Adverse event: Fatigue
Serious: yes
Organ System: General disorders
Notes: Drug related
Frequency: 17 affected / 495 at risk

Adverse event: Thrombocythamia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 495 at risk

Adverse event: Cardiomyopathy
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 495 at risk

Adverse event: Cardiopulmonary failure
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 495 at risk

Adverse event: Myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 495 at risk

Adverse event: Pericardial effusion
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 495 at risk

Adverse event: Sinus tachycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 495 at risk

Adverse event: Ventricular tachycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 495 at risk

Adverse event: Abdominal hernia
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 495 at risk

Adverse event: Ascites
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 495 at risk

Adverse event: Dyspepsia
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 495 at risk

Adverse event: Faecaloma
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 495 at risk

Adverse event: Gastric haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 495 at risk

Adverse event: Gastric ulcer
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 495 at risk

Adverse event: Haemorrhoids
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 495 at risk

Adverse event: Multiple organ dysfunction syndrome
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 495 at risk

Adverse event: Oedema
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 495 at risk

Adverse event: Pain
Serious: yes
Organ System: General disorders
Frequency: 3 affected / 495 at risk

Adverse event: Cholecystitis
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 495 at risk

Adverse event: Hepatic failure
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 495 at risk

Adverse event: Abscess limb
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 495 at risk

Adverse event: Abscess soft tissue
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 495 at risk

Adverse event: Genitourinary tract infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 495 at risk

Adverse event: Lower respiratory tract infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 495 at risk

Adverse event: Nail bed infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 495 at risk

Adverse event: Respiratory tract infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 495 at risk

Adverse event: Tooth abscess
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 495 at risk

Adverse event: Femur fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 495 at risk

Adverse event: Overdose
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 495 at risk

Adverse event: Wound complication
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 495 at risk

Adverse event: Wound dehiscence
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 495 at risk

Adverse event: Blood bilirubin increased
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 495 at risk

Adverse event: Hyperkaelemia
Serious: yes
Organ System: Investigations
Frequency: 1 affected / 495 at risk

Adverse event: Diabetes mellitus
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 495 at risk

Adverse event: Hyperkalaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 495 at risk

Adverse event: Metabolic alkalosis
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 495 at risk

Adverse event: Back pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 495 at risk

Adverse event: Osteitis
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 495 at risk

Adverse event: Malignant neoplasm progression
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 495 at risk

Adverse event: Metastases to central nervous system
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 495 at risk

Adverse event: Coma
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 495 at risk

Adverse event: Seizure
Serious: yes
Organ System: Nervous system disorders
Frequency: 4 affected / 495 at risk

Adverse event: Depressed level of consciouness
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 495 at risk

Adverse event: Dizziness
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 495 at risk

Adverse event: Hydrocephalus
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 495 at risk

Adverse event: Memory impairment
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 495 at risk

Adverse event: Anxiety
Serious: yes
Organ System: Psychiatric disorders
Frequency: 2 affected / 495 at risk

Adverse event: Confusional state
Serious: yes
Organ System: Psychiatric disorders
Frequency: 2 affected / 495 at risk

Adverse event: Insomnia
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 495 at risk

Adverse event: Suicide attempt
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 495 at risk

Adverse event: Oliguria
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 495 at risk

Adverse event: Renal failure
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 495 at risk

Adverse event: Intermenstrual bleeding
Serious: yes
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 495 at risk

Adverse event: Aspiration
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 495 at risk

Adverse event: Bronchospasm
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 495 at risk

Adverse event: Cough
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 495 at risk

Adverse event: Hypoxia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 2 affected / 495 at risk

Adverse event: Lung infiltration
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 495 at risk

Adverse event: Pleural effusion
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 7 affected / 495 at risk

Adverse event: Pneumonia aspiration
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 495 at risk

Adverse event: Pneumothorax
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 3 affected / 495 at risk

Adverse event: Cancer surgery
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 1 affected / 495 at risk

Adverse event: Deep venous thrombosis
Serious: yes
Organ System: Vascular disorders
Frequency: 2 affected / 495 at risk

Adverse event: Hypertension
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 495 at risk

Adverse event: Phlebitis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 495 at risk

Adverse event: Thrombophlebitis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 495 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 159 affected / 495 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 34 affected / 495 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 295 affected / 495 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 61 affected / 495 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 175 affected / 495 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 70 affected / 495 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 239 affected / 495 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 111 affected / 495 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 266 affected / 495 at risk

Adverse event: Stomatitis
Serious: no
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 169 affected / 495 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 216 affected / 495 at risk

Adverse event: Asthenia
Serious: no
Organ System: General disorders
Notes: Drug related
Frequency: 56 affected / 495 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Notes: Drug related
Frequency: 314 affected / 495 at risk

Adverse event: Injection site reaction
Serious: no
Organ System: General disorders
Notes: Drug related
Frequency: 74 affected / 495 at risk

Adverse event: Oedema peripheral
Serious: no
Organ System: General disorders
Notes: Drug related
Frequency: 76 affected / 495 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Notes: Drug related
Frequency: 49 affected / 495 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Notes: Drug related
Frequency: 124 affected / 495 at risk

Adverse event: Weight decreased
Serious: no
Organ System: Investigations
Notes: Drug related
Frequency: 166 affected / 495 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Notes: Drug related
Frequency: 164 affected / 495 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 73 affected / 495 at risk

Adverse event: Bone pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 101 affected / 495 at risk

Adverse event: Myalgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 104 affected / 495 at risk

Adverse event: Pain in extremity
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 93 affected / 495 at risk

Adverse event: Dysgeusia
Serious: no
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 19 affected / 495 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 88 affected / 495 at risk

Adverse event: Paraesthesia
Serious: no
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 22 affected / 495 at risk

Adverse event: Peripheral motor neuropathy
Serious: no
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 11 affected / 495 at risk

Adverse event: Peripheral sensory neuropathy
Serious: no
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 66 affected / 495 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 126 affected / 495 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Drug related
Frequency: 202 affected / 495 at risk

Adverse event: Rash
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 39 affected / 495 at risk

Adverse event: Phlebitis
Serious: no
Organ System: Vascular disorders
Notes: Drug related
Frequency: 39 affected / 495 at risk

Adverse event: Febrile neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 25 affected / 495 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 36 affected / 495 at risk

Adverse event: Chest pain
Serious: no
Organ System: General disorders
Frequency: 57 affected / 495 at risk

Adverse event: Influenza like illness
Serious: no
Organ System: General disorders
Frequency: 39 affected / 495 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 27 affected / 495 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 37 affected / 495 at risk

Adverse event: Alanine aminotransferase increased
Serious: no
Organ System: Investigations
Frequency: 25 affected / 495 at risk

Adverse event: Weight increased
Serious: no
Organ System: Investigations
Frequency: 44 affected / 495 at risk

Adverse event: Dehydration
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 33 affected / 495 at risk

Adverse event: Hypokalaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 40 affected / 495 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 92 affected / 495 at risk

Adverse event: Musculoskeletal chest pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 30 affected / 495 at risk

Adverse event: Musculoskeletal pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 48 affected / 495 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 25 affected / 495 at risk

Adverse event: Psychiatric disorders
Serious: no
Organ System: Nervous system disorders
Frequency: 140 affected / 495 at risk

Adverse event: Anxiety
Serious: no
Organ System: Nervous system disorders
Frequency: 51 affected / 495 at risk

Adverse event: Depression
Serious: no
Organ System: Nervous system disorders
Frequency: 29 affected / 495 at risk

Adverse event: Insomnia
Serious: no
Organ System: Nervous system disorders
Frequency: 81 affected / 495 at risk

Adverse event: Anaemia
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 7 affected / 496 at risk

Adverse event: Febrile neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 8 affected / 496 at risk

Adverse event: Leukopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 3 affected / 496 at risk

Adverse event: Neutropenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 10 affected / 496 at risk

Adverse event: Thrombocytopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 4 affected / 496 at risk

Adverse event: Atrial fibrillation
Serious: yes
Organ System: Cardiac disorders
Notes: Drug related
Frequency: 2 affected / 496 at risk

Adverse event: Abdominal pain
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Constipation
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Diarrhoea
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 6 affected / 496 at risk

Adverse event: Gastritis
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Ileus
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Intestinal obstruction
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Nausea
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Stomatitis
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 2 affected / 496 at risk

Adverse event: Vomiting
Serious: yes
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 4 affected / 496 at risk

Adverse event: Asthenia
Serious: yes
Organ System: General disorders
Notes: Drug related
Frequency: 3 affected / 496 at risk

Adverse event: Chest pain
Serious: yes
Organ System: General disorders
Notes: Drug related
Frequency: 6 affected / 496 at risk

Adverse event: Condition aggravated
Serious: yes
Organ System: General disorders
Notes: Drug related
Frequency: 3 affected / 496 at risk

Adverse event: Pyrexia
Serious: yes
Organ System: General disorders
Notes: Drug related
Frequency: 13 affected / 496 at risk

Adverse event: Hepatic function abnormal
Serious: yes
Organ System: Hepatobiliary disorders
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Hyperbilirubinaemia
Serious: yes
Organ System: Hepatobiliary disorders
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Anaphylactic reaction
Serious: yes
Organ System: Immune system disorders
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Hypersensitivity
Serious: yes
Organ System: Immune system disorders
Notes: Drug related
Frequency: 3 affected / 496 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Catheter-related infection
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 2 affected / 496 at risk

Adverse event: Cellulitis
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Erysipelas
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Gastroenteritis
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Infection
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 2 affected / 496 at risk

Adverse event: Mastitis
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Neutropenic infection
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 4 affected / 496 at risk

Adverse event: Oral candidiasis
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 2 affected / 496 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 13 affected / 496 at risk

Adverse event: Sepsis
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 2 affected / 496 at risk

Adverse event: Septic shock
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 2 affected / 496 at risk

Adverse event: Staphylococcal sepsis
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Upper respiratory tract infection
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Urinary tract infection
Serious: yes
Organ System: Infections and infestations
Notes: Drug related
Frequency: 3 affected / 496 at risk

Adverse event: Alanine aminotransferase increased
Serious: yes
Organ System: Investigations
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Aspartate aminotransferase increased
Serious: yes
Organ System: Investigations
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Blood creatinine increased
Serious: yes
Organ System: Investigations
Notes: Drug related
Frequency: 2 affected / 496 at risk

Adverse event: Transaminases increased
Serious: yes
Organ System: Investigations
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Decreased appetite
Serious: yes
Organ System: Metabolism and nutrition disorders
Notes: Drug related
Frequency: 5 affected / 496 at risk

Adverse event: Dehydration
Serious: yes
Organ System: Metabolism and nutrition disorders
Notes: Drug related
Frequency: 2 affected / 496 at risk

Adverse event: Hyperglycaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Notes: Drug related
Frequency: 3 affected / 496 at risk

Adverse event: Hypovolaemia
Serious: yes
Organ System: Metabolism and nutrition disorders
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Bone pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Pain in extremity
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 2 affected / 496 at risk

Adverse event: Headache
Serious: yes
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 2 affected / 496 at risk

Adverse event: Syncope
Serious: yes
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 11 affected / 496 at risk

Adverse event: Lung disorder
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 2 affected / 496 at risk

Adverse event: Orthopnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Pulmonary embolism
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 2 affected / 496 at risk

Adverse event: Respiratory failure
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 2 affected / 496 at risk

Adverse event: Embolism
Serious: yes
Organ System: Vascular disorders
Notes: Drug related
Frequency: 1 affected / 496 at risk

Adverse event: Hypotension
Serious: yes
Organ System: Vascular disorders
Notes: Drug related
Frequency: 3 affected / 496 at risk

Adverse event: Superior vena cava occlusion
Serious: yes
Organ System: Vascular disorders
Notes: Drug related
Frequency: 2 affected / 496 at risk

Adverse event: Fatigue
Serious: yes
Organ System: General disorders
Notes: Drug related
Frequency: 5 affected / 496 at risk

Adverse event: Arrhythmia supraventricular
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 496 at risk

Adverse event: Cardiac failure
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 496 at risk

Adverse event: Myocardial ischaemia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 496 at risk

Adverse event: Pericardial effusion
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 496 at risk

Adverse event: Stress cardiomyopathy
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 496 at risk

Adverse event: Blindness unilateral
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 496 at risk

Adverse event: Ascites
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 496 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 496 at risk

Adverse event: Generalized oedema
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 496 at risk

Adverse event: Oedema peripheral
Serious: yes
Organ System: General disorders
Frequency: 1 affected / 496 at risk

Adverse event: Cholangitis
Serious: yes
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 496 at risk

Adverse event: Bronchitis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 496 at risk

Adverse event: Lower respiratory tract infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 496 at risk

Adverse event: Respiratory tract infection
Serious: yes
Organ System: Infections and infestations
Frequency: 3 affected / 496 at risk

Adverse event: Viral pericarditis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 496 at risk

Adverse event: Forearm fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 496 at risk

Adverse event: Pelvic fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 496 at risk

Adverse event: Pneumothorax traumatic
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 496 at risk

Adverse event: Thermal burn
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 496 at risk

Adverse event: Wound
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 496 at risk

Adverse event: Diabetes mellitus
Serious: yes
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 496 at risk

Adverse event: Back pain
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 496 at risk

Adverse event: Myopathy
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 496 at risk

Adverse event: Malignant neoplasm progression
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 2 affected / 496 at risk

Adverse event: Malignant pleural effusion
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 496 at risk

Adverse event: Cognitive disorder
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 496 at risk

Adverse event: Seizure
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 496 at risk

Adverse event: Intracranial pressure increased
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 496 at risk

Adverse event: Polyneuropathy
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 496 at risk

Adverse event: Confusional state
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 496 at risk

Adverse event: Schizoaffective disorder
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 496 at risk

Adverse event: Hydronephrosis
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 496 at risk

Adverse event: Renal disorder
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 496 at risk

Adverse event: Renal failure
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 496 at risk

Adverse event: Bronchospasm
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 496 at risk

Adverse event: Chronic pulmonary obstructive disease
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 496 at risk

Adverse event: Hypoxia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 496 at risk

Adverse event: Obstructive airways disorder
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 496 at risk

Adverse event: Pleural effusion
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 7 affected / 496 at risk

Adverse event: Pneumonitis
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 496 at risk

Adverse event: Diabetes mellitus management
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 1 affected / 496 at risk

Adverse event: Cancer surgery
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 1 affected / 496 at risk

Adverse event: Hypertension
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 496 at risk

Adverse event: Hypovolaemic shock
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 496 at risk

Adverse event: Lymphooedema
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 496 at risk

Adverse event: Phlebitis
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 496 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 94 affected / 496 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 27 affected / 496 at risk

Adverse event: Neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 249 affected / 496 at risk

Adverse event: Thrombocytopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Drug related
Frequency: 87 affected / 496 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 87 affected / 496 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 39 affected / 496 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 126 affected / 496 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 137 affected / 496 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 220 affected / 496 at risk

Adverse event: Stomatitis
Serious: no
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 85 affected / 496 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Notes: Drug related
Frequency: 134 affected / 496 at risk

Adverse event: Asthenia
Serious: no
Organ System: General disorders
Notes: Drug related
Frequency: 46 affected / 496 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Notes: Drug related
Frequency: 286 affected / 496 at risk

Adverse event: Injection site reaction
Serious: no
Organ System: General disorders
Notes: Drug related
Frequency: 19 affected / 496 at risk

Adverse event: Oedema peripheral
Serious: no
Organ System: General disorders
Notes: Drug related
Frequency: 86 affected / 496 at risk

Adverse event: Pain
Serious: no
Organ System: General disorders
Notes: Drug related
Frequency: 40 affected / 496 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Notes: Drug related
Frequency: 133 affected / 496 at risk

Adverse event: Weight decreased
Serious: no
Organ System: Investigations
Notes: Drug related
Frequency: 126 affected / 496 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Notes: Drug related
Frequency: 119 affected / 496 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 90 affected / 496 at risk

Adverse event: Bone pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 103 affected / 496 at risk

Adverse event: Myalgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 116 affected / 496 at risk

Adverse event: Pain in extremity
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Drug related
Frequency: 104 affected / 496 at risk

Adverse event: Dysgeusia
Serious: no
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 34 affected / 496 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 66 affected / 496 at risk

Adverse event: Paraesthesia
Serious: no
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 75 affected / 496 at risk

Adverse event: Peripheral motor neuropathy
Serious: no
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 34 affected / 496 at risk

Adverse event: Peripheral sensory neuropathy
Serious: no
Organ System: Nervous system disorders
Notes: Drug related
Frequency: 226 affected / 496 at risk

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 128 affected / 496 at risk

Adverse event: Alopecia
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Drug related
Frequency: 317 affected / 496 at risk

Adverse event: Rash
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Drug related
Frequency: 65 affected / 496 at risk

Adverse event: Phlebitis
Serious: no
Organ System: Vascular disorders
Notes: Drug related
Frequency: 12 affected / 496 at risk

Adverse event: Febrile neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 13 affected / 496 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 27 affected / 496 at risk

Adverse event: Chest pain
Serious: no
Organ System: General disorders
Frequency: 49 affected / 496 at risk

Adverse event: Influenza like illness
Serious: no
Organ System: General disorders
Frequency: 39 affected / 496 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 34 affected / 496 at risk

Adverse event: Urinary tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 37 affected / 496 at risk

Adverse event: Alanine aminotransferase increased
Serious: no
Organ System: Investigations
Frequency: 27 affected / 496 at risk

Adverse event: Weight increased
Serious: no
Organ System: Investigations
Frequency: 67 affected / 496 at risk

Adverse event: Dehydration
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 7 affected / 496 at risk

Adverse event: Hypokalaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 14 affected / 496 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 91 affected / 496 at risk

Adverse event: Musculoskeletal chest pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 24 affected / 496 at risk

Adverse event: Musculoskeletal pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 36 affected / 496 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 27 affected / 496 at risk

Adverse event: Psychiatric disorders
Serious: no
Organ System: Nervous system disorders
Frequency: 109 affected / 496 at risk

Adverse event: Anxiety
Serious: no
Organ System: Nervous system disorders
Frequency: 46 affected / 496 at risk

Adverse event: Depression
Serious: no
Organ System: Nervous system disorders
Frequency: 24 affected / 496 at risk

Adverse event: Insomnia
Serious: no
Organ System: Nervous system disorders
Frequency: 57 affected / 496 at risk