Study: NCT02652780

Adverse event: Acute myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 37 at risk

Adverse event: Retinal tear
Serious: yes
Organ System: Eye disorders
Notes: This event occurred only in an eye receiving the sham procedure.
Frequency: 1 affected / 37 at risk

Adverse event: Intestinal perforation
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 37 at risk

Adverse event: Diverticulitis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 37 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 37 at risk

Adverse event: Arthropod bite
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 2 affected / 37 at risk

Adverse event: Gamma-glutamyl transferase increased
Serious: no
Organ System: Investigations
Frequency: 8 affected / 37 at risk

Adverse event: Alanine aminotransferase increased
Serious: no
Organ System: Investigations
Frequency: 4 affected / 37 at risk

Adverse event: Aspartate aminotransferase increased
Serious: no
Organ System: Investigations
Frequency: 2 affected / 37 at risk

Adverse event: Drug hypersensitivity
Serious: no
Organ System: Immune system disorders
Frequency: 2 affected / 37 at risk

Adverse event: Alcohol use
Serious: no
Organ System: Social circumstances
Frequency: 2 affected / 37 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 37 at risk

Adverse event: Paraesthesia
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 37 at risk

Adverse event: Anterior chamber cell
Serious: no
Organ System: Eye disorders
Frequency: 9 affected / 37 at risk

Adverse event: Autoimmune uveitis
Serious: no
Organ System: Eye disorders
Notes: The verbatim AE term is "intermediate uveitis". 1/14 affected participants experienced this event only in sham-treated eyes.
Frequency: 14 affected / 37 at risk

Adverse event: Cataract
Serious: no
Organ System: Eye disorders
Notes: 1/4 affected participants experienced this event only in sham-treated eyes
Frequency: 4 affected / 37 at risk

Adverse event: Conjunctival haemorrhage
Serious: no
Organ System: Eye disorders
Notes: 3/6 affected participants experienced this event only in sham-treated eyes.
Frequency: 6 affected / 37 at risk

Adverse event: Conjunctival hyperaemia
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 37 at risk

Adverse event: Dry eye
Serious: no
Organ System: Eye disorders
Notes: 1/2 affected participants experienced this event only in sham-treated eyes.
Frequency: 2 affected / 37 at risk

Adverse event: Iridocyclitis
Serious: no
Organ System: Eye disorders
Notes: 1/15 affected participants experienced this event only in sham-treated eyes.
Frequency: 15 affected / 37 at risk

Adverse event: Iritis
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 37 at risk

Adverse event: Keratic precipitates
Serious: no
Organ System: Eye disorders
Frequency: 13 affected / 37 at risk

Adverse event: Eye pain
Serious: no
Organ System: Eye disorders
Notes: 1/3 affected participants experienced this event only in sham-treated eyes.
Frequency: 3 affected / 37 at risk

Adverse event: Intraocular pressure increased
Serious: no
Organ System: Eye disorders
Notes: 1/11 affected participants experienced this event only in sham-treated eyes.
Frequency: 11 affected / 37 at risk

Adverse event: Vitritis
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 37 at risk

Adverse event: Vitreous floaters
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 37 at risk

Adverse event: Vitreous detachment
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 37 at risk

Adverse event: Vitreal cells
Serious: no
Organ System: Eye disorders
Notes: 1/7 affected participants experienced this event only in sham-treated eyes.
Frequency: 7 affected / 37 at risk

Adverse event: Visual impairment
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 37 at risk

Adverse event: Punctate keratitis
Serious: no
Organ System: Eye disorders
Notes: 4/15 affected participants experienced this event only in sham-treated eyes.
Frequency: 15 affected / 37 at risk

Adverse event: Depression
Serious: no
Organ System: Psychiatric disorders
Frequency: 2 affected / 37 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 37 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 37 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 6 affected / 37 at risk