Study: NCT01570829

Adverse event: Glomerulonephritis membranous
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 164 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 164 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 164 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 164 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 164 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 164 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Notes: Heartburn
Frequency: 1 affected / 164 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 164 at risk

Adverse event: Viral respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 13 affected / 164 at risk

Adverse event: Nail bed infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 164 at risk

Adverse event: Candida infection
Serious: no
Organ System: Infections and infestations
Notes: Thrush
Frequency: 1 affected / 164 at risk

Adverse event: Respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 164 at risk

Adverse event: Tooth pulpitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 164 at risk

Adverse event: Deviation from the ESR norm
Serious: no
Organ System: Investigations
Frequency: 1 affected / 164 at risk

Adverse event: Blood pressure increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 164 at risk

Adverse event: Increased ESR
Serious: no
Organ System: Investigations
Frequency: 2 affected / 164 at risk

Adverse event: Increased ALT
Serious: no
Organ System: Investigations
Frequency: 2 affected / 164 at risk

Adverse event: Increased AST
Serious: no
Organ System: Investigations
Frequency: 1 affected / 164 at risk

Adverse event: Increased blood glucose
Serious: no
Organ System: Investigations
Frequency: 4 affected / 164 at risk

Adverse event: Increased lymphocytes
Serious: no
Organ System: Investigations
Frequency: 1 affected / 164 at risk

Adverse event: Increase in LDL cholesterol
Serious: no
Organ System: Investigations
Frequency: 1 affected / 164 at risk

Adverse event: Increased monocytes
Serious: no
Organ System: Investigations
Frequency: 1 affected / 164 at risk

Adverse event: Elevated LDL
Serious: no
Organ System: Investigations
Frequency: 1 affected / 164 at risk

Adverse event: Decreased platelets
Serious: no
Organ System: Investigations
Frequency: 1 affected / 164 at risk

Adverse event: Weight increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 164 at risk

Adverse event: Increased LDL to HDL ratio
Serious: no
Organ System: Investigations
Frequency: 1 affected / 164 at risk

Adverse event: Hyperuricaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 164 at risk

Adverse event: Dyslipidaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 3 affected / 164 at risk

Adverse event: Impaired fasting glycemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 164 at risk

Adverse event: Type 2 diabetes mellitus
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 164 at risk

Adverse event: Increased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 3 affected / 164 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Lumbago
Frequency: 1 affected / 164 at risk

Adverse event: Osteoarthritis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Deforming osteoarthritis
Frequency: 1 affected / 164 at risk

Adverse event: Bone cyst
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 164 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 164 at risk

Adverse event: Migraine
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 164 at risk

Adverse event: Cranial nerve neuritis
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 164 at risk

Adverse event: Menstrual disorders
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 164 at risk

Adverse event: Ventricular extrasystoles
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 164 at risk

Adverse event: Deep vein thrombosis
Serious: no
Organ System: Vascular disorders
Notes: Tibial vein thrombosis
Frequency: 1 affected / 164 at risk

Adverse event: Asthenia
Serious: no
Organ System: General disorders
Frequency: 2 affected / 164 at risk

Adverse event: Increased body temperature
Serious: no
Organ System: General disorders
Frequency: 1 affected / 164 at risk

Adverse event: Decreased activity
Serious: no
Organ System: General disorders
Frequency: 1 affected / 164 at risk

Adverse event: Depression
Serious: no
Organ System: Psychiatric disorders
Frequency: 18 affected / 164 at risk

Adverse event: Depression, worsening
Serious: no
Organ System: Psychiatric disorders
Frequency: 12 affected / 164 at risk

Adverse event: Feeling of elation
Serious: no
Organ System: Psychiatric disorders
Notes: Euphoric mood
Frequency: 1 affected / 164 at risk

Adverse event: Increased anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 32 affected / 164 at risk

Adverse event: Bruised toe
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 164 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 167 at risk

Adverse event: Complicated appendicitis
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 167 at risk

Adverse event: Ankle fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Notes: Closed fracture of the right leg and right foot as a result of a fall
Frequency: 1 affected / 167 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 167 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 167 at risk

Adverse event: Dyspepsia
Serious: no
Organ System: Gastrointestinal disorders
Notes: Heartburn
Frequency: 1 affected / 167 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 167 at risk

Adverse event: Viral respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 8 affected / 167 at risk

Adverse event: Respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 167 at risk

Adverse event: Bronchitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 167 at risk

Adverse event: Tracheitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 167 at risk

Adverse event: Chronic hepatitis C
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 167 at risk

Adverse event: Abnormal glucose tolerance test results
Serious: no
Organ System: Investigations
Frequency: 2 affected / 167 at risk

Adverse event: Blood pressure increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 167 at risk

Adverse event: Increased ESR
Serious: no
Organ System: Investigations
Frequency: 1 affected / 167 at risk

Adverse event: Increased blood glucose
Serious: no
Organ System: Investigations
Frequency: 2 affected / 167 at risk

Adverse event: Increased monocytes
Serious: no
Organ System: Investigations
Frequency: 1 affected / 167 at risk

Adverse event: Platelet count increased
Serious: no
Organ System: Investigations
Frequency: 2 affected / 167 at risk

Adverse event: Increased eosinophils
Serious: no
Organ System: Investigations
Frequency: 2 affected / 167 at risk

Adverse event: Increased red blood cells
Serious: no
Organ System: Investigations
Frequency: 2 affected / 167 at risk

Adverse event: Elevated triglycerides
Serious: no
Organ System: Investigations
Frequency: 2 affected / 167 at risk

Adverse event: Decreased serum creatinine levels
Serious: no
Organ System: Investigations
Frequency: 1 affected / 167 at risk

Adverse event: Weight increased
Serious: no
Organ System: Investigations
Frequency: 1 affected / 167 at risk

Adverse event: Hypercholesterolaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 167 at risk

Adverse event: Dyslipidaemia
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 2 affected / 167 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 167 at risk

Adverse event: Increased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 6 affected / 167 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 167 at risk

Adverse event: Anaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 167 at risk

Adverse event: Spinal osteoarthritis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: Degenerative changes in the thoracic spine
Frequency: 1 affected / 167 at risk

Adverse event: Psychomotor hyperactivity
Serious: no
Organ System: Nervous system disorders
Notes: Psychomotor hyperactivity
Frequency: 1 affected / 167 at risk

Adverse event: Retinal dystrophy
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 167 at risk

Adverse event: Cholelithiasis
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 167 at risk

Adverse event: Cholecystitis chronic
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 167 at risk

Adverse event: Bartholin's gland cyst
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 167 at risk

Adverse event: Tachycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 167 at risk

Adverse event: Hypertension
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 167 at risk

Adverse event: Hypertensive crisis
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 167 at risk

Adverse event: Hypotension
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 167 at risk

Adverse event: Chest pain
Serious: no
Organ System: General disorders
Frequency: 1 affected / 167 at risk

Adverse event: Thirst
Serious: no
Organ System: General disorders
Frequency: 1 affected / 167 at risk

Adverse event: Insomnia
Serious: no
Organ System: Psychiatric disorders
Frequency: 1 affected / 167 at risk

Adverse event: Depression
Serious: no
Organ System: Psychiatric disorders
Frequency: 10 affected / 167 at risk

Adverse event: Depression, worsening
Serious: no
Organ System: Psychiatric disorders
Frequency: 13 affected / 167 at risk

Adverse event: Feeling of elation
Serious: no
Organ System: Psychiatric disorders
Notes: Euphoric mood
Frequency: 1 affected / 167 at risk

Adverse event: Increased anxiety
Serious: no
Organ System: Psychiatric disorders
Frequency: 36 affected / 167 at risk