Study: NCT00001213

Adverse event: Optic disc disorder
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 328 at risk

Adverse event: Renal failure
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 2 affected / 328 at risk

Adverse event: Blindness
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 328 at risk

Adverse event: Idiopathic intracranial hypertension
Serious: yes
Organ System: Nervous system disorders
Frequency: 8 affected / 328 at risk

Adverse event: Gastrointestinal infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 328 at risk

Adverse event: Intestinal obstruction
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 328 at risk

Adverse event: Photophobia
Serious: no
Organ System: Eye disorders
Frequency: 239 affected / 328 at risk

Adverse event: Conjunctival hyperaemia
Serious: no
Organ System: Eye disorders
Frequency: 69 affected / 328 at risk

Adverse event: Eye pain
Serious: no
Organ System: Eye disorders
Frequency: 66 affected / 328 at risk

Adverse event: Ocular hyperaemia
Serious: no
Organ System: Eye disorders
Frequency: 52 affected / 328 at risk

Adverse event: Eye irritation
Serious: no
Organ System: Eye disorders
Frequency: 49 affected / 328 at risk

Adverse event: Lacrimation increased
Serious: no
Organ System: Eye disorders
Frequency: 23 affected / 328 at risk

Adverse event: Optic disc disorder
Serious: no
Organ System: Eye disorders
Frequency: 19 affected / 328 at risk

Adverse event: Vision blurred
Serious: no
Organ System: Eye disorders
Frequency: 20 affected / 328 at risk

Adverse event: Keratitis
Serious: no
Organ System: Eye disorders
Frequency: 19 affected / 328 at risk

Adverse event: Dry eye
Serious: no
Organ System: Eye disorders
Frequency: 14 affected / 328 at risk

Adverse event: Eye pruritis
Serious: no
Organ System: Eye disorders
Frequency: 13 affected / 328 at risk

Adverse event: Conjunctivitis
Serious: no
Organ System: Eye disorders
Frequency: 12 affected / 328 at risk

Adverse event: Eyelid oedema
Serious: no
Organ System: Eye disorders
Frequency: 12 affected / 328 at risk

Adverse event: Retinal disorder
Serious: no
Organ System: Eye disorders
Frequency: 11 affected / 328 at risk

Adverse event: Blindness
Serious: no
Organ System: Eye disorders
Frequency: 9 affected / 328 at risk

Adverse event: Corneal disorder
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 328 at risk

Adverse event: Blepharitis
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 328 at risk

Adverse event: Erythema of eyelid
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 328 at risk

Adverse event: Eye swelling
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 328 at risk

Adverse event: Conjunctival oedema
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 328 at risk

Adverse event: Eye oedema
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 328 at risk

Adverse event: Eyelid cyst
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 328 at risk

Adverse event: Eyelid irritation
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 328 at risk

Adverse event: Ulcerative keratitis
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 328 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 94 affected / 328 at risk

Adverse event: Visual field defect
Serious: no
Organ System: Nervous system disorders
Frequency: 35 affected / 328 at risk

Adverse event: Idiopathic intracranial hypertension
Serious: no
Organ System: Nervous system disorders
Frequency: 4 affected / 328 at risk

Adverse event: Instillation site irritation
Serious: no
Organ System: General disorders
Frequency: 33 affected / 328 at risk

Adverse event: Instillation site pain
Serious: no
Organ System: General disorders
Frequency: 22 affected / 328 at risk

Adverse event: Adverse drug reaction
Serious: no
Organ System: General disorders
Frequency: 7 affected / 328 at risk

Adverse event: Instillation site erythema
Serious: no
Organ System: General disorders
Frequency: 5 affected / 328 at risk

Adverse event: Swelling
Serious: no
Organ System: General disorders
Frequency: 2 affected / 328 at risk

Adverse event: Drug ineffective
Serious: no
Organ System: Eye disorders
Frequency: 1 affected / 328 at risk

Adverse event: Instillation site lacrimation
Serious: no
Organ System: General disorders
Frequency: 1 affected / 328 at risk

Adverse event: Instillation site reaction
Serious: no
Organ System: General disorders
Frequency: 1 affected / 328 at risk

Adverse event: Eye infection
Serious: no
Organ System: Infections and infestations
Frequency: 6 affected / 328 at risk

Adverse event: Conjunctivitis ineffective
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 328 at risk

Adverse event: Hordeolum
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 328 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 8 affected / 328 at risk

Adverse event: Abdominal pain
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 328 at risk

Adverse event: Drug hypersensitivity
Serious: no
Organ System: Immune system disorders
Frequency: 2 affected / 328 at risk

Adverse event: Visual evoked potentials abnormal
Serious: no
Organ System: Investigations
Frequency: 1 affected / 328 at risk