Study: NCT01408901

Adverse event: Cardiovascular event
Serious: yes
Organ System: Cardiac disorders
Frequency: 4 affected / 53 at risk

Adverse event: Diabetes mellitus
Serious: yes
Organ System: Endocrine disorders
Frequency: 1 affected / 53 at risk

Adverse event: General event
Serious: yes
Organ System: General disorders
Frequency: 7 affected / 53 at risk

Adverse event: Infection
Serious: yes
Organ System: Infections and infestations
Frequency: 3 affected / 53 at risk

Adverse event: Neoplasm malignant
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 53 at risk

Adverse event: Vascular
Serious: yes
Organ System: Vascular disorders
Frequency: 2 affected / 53 at risk

Adverse event: Aching or soreness in feet
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 38 affected / 53 at risk

Adverse event: Aching or soreness in thighs
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 27 affected / 53 at risk

Adverse event: Aching or soreness in lower back
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 34 affected / 53 at risk

Adverse event: Aching or soreness in knee joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 27 affected / 53 at risk

Adverse event: Aching or soreness in other joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 14 affected / 53 at risk

Adverse event: Aching or soreness in calves
Serious: no
Organ System: Vascular disorders
Frequency: 40 affected / 53 at risk

Adverse event: Aching or soreness in buttocks
Serious: no
Organ System: Vascular disorders
Frequency: 25 affected / 53 at risk

Adverse event: Aching or soreness in other areas
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 31 affected / 53 at risk

Adverse event: Aching or soreness in hip joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 23 affected / 53 at risk

Adverse event: Increase in shortness of breath
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 10 affected / 53 at risk

Adverse event: New chest pain
Serious: no
Organ System: General disorders
Frequency: 4 affected / 53 at risk

Adverse event: Fever greater than 101 degrees
Serious: no
Organ System: General disorders
Frequency: 3 affected / 53 at risk

Adverse event: Chills
Serious: no
Organ System: General disorders
Frequency: 12 affected / 53 at risk

Adverse event: New headaches
Serious: no
Organ System: General disorders
Frequency: 25 affected / 53 at risk

Adverse event: Pain in muscles
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 40 affected / 53 at risk

Adverse event: Nausea or vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 13 affected / 53 at risk

Adverse event: New rash
Serious: no
Organ System: General disorders
Frequency: 11 affected / 53 at risk

Adverse event: New swelling in hands or feet
Serious: no
Organ System: General disorders
Frequency: 18 affected / 53 at risk

Adverse event: Pain in bones
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 20 affected / 53 at risk

Adverse event: Pulmonary embolism
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 53 at risk

Adverse event: Other type of blood clotting or thrombosis
Serious: no
Organ System: Vascular disorders
Frequency: 2 affected / 53 at risk

Adverse event: Cardiovascular event
Serious: yes
Organ System: Cardiac disorders
Frequency: 5 affected / 53 at risk

Adverse event: Gastrointestinal haemorrhage
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 53 at risk

Adverse event: General event
Serious: yes
Organ System: General disorders
Frequency: 5 affected / 53 at risk

Adverse event: Infection
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 53 at risk

Adverse event: Injury
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 53 at risk

Adverse event: Renal failure
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 53 at risk

Adverse event: Vascular
Serious: yes
Organ System: Vascular disorders
Frequency: 1 affected / 53 at risk

Adverse event: Aching or soreness in feet
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 36 affected / 53 at risk

Adverse event: Aching or soreness in thighs
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 27 affected / 53 at risk

Adverse event: Aching or soreness in lower back
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 37 affected / 53 at risk

Adverse event: Aching or soreness in knee joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 26 affected / 53 at risk

Adverse event: Aching or soreness in other joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 17 affected / 53 at risk

Adverse event: Aching or soreness in calves
Serious: no
Organ System: Vascular disorders
Frequency: 35 affected / 53 at risk

Adverse event: Aching or soreness in buttocks
Serious: no
Organ System: Vascular disorders
Frequency: 23 affected / 53 at risk

Adverse event: Aching or soreness in other areas
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 30 affected / 53 at risk

Adverse event: Aching or soreness in hip joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 23 affected / 53 at risk

Adverse event: Increase in shortness of breath
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 12 affected / 53 at risk

Adverse event: New chest pain
Serious: no
Organ System: General disorders
Frequency: 5 affected / 53 at risk

Adverse event: Fever greater than 101 degrees
Serious: no
Organ System: General disorders
Frequency: 3 affected / 53 at risk

Adverse event: Chills
Serious: no
Organ System: General disorders
Frequency: 22 affected / 53 at risk

Adverse event: New headaches
Serious: no
Organ System: General disorders
Frequency: 24 affected / 53 at risk

Adverse event: Pain in muscles
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 38 affected / 53 at risk

Adverse event: Nausea or vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 17 affected / 53 at risk

Adverse event: New rash
Serious: no
Organ System: General disorders
Frequency: 11 affected / 53 at risk

Adverse event: New swelling in hands or feet
Serious: no
Organ System: General disorders
Frequency: 18 affected / 53 at risk

Adverse event: Pain in bones
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 19 affected / 53 at risk

Adverse event: Other type of blood clotting or thrombosis
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 53 at risk

Adverse event: Cardiovascular event
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 53 at risk

Adverse event: General event
Serious: yes
Organ System: General disorders
Frequency: 4 affected / 53 at risk

Adverse event: Infection
Serious: yes
Organ System: Infections and infestations
Frequency: 1 affected / 53 at risk

Adverse event: Vascular
Serious: yes
Organ System: Vascular disorders
Frequency: 2 affected / 53 at risk

Adverse event: Aching or soreness in feet
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 29 affected / 53 at risk

Adverse event: Aching or soreness in thighs
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 26 affected / 53 at risk

Adverse event: Aching or soreness in lower back
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 32 affected / 53 at risk

Adverse event: Aching or soreness in knee joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 33 affected / 53 at risk

Adverse event: Aching or soreness in other joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 16 affected / 53 at risk

Adverse event: Aching or soreness in calves
Serious: no
Organ System: Vascular disorders
Frequency: 36 affected / 53 at risk

Adverse event: Aching or soreness in buttocks
Serious: no
Organ System: Vascular disorders
Frequency: 22 affected / 53 at risk

Adverse event: Aching or soreness in other areas
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 28 affected / 53 at risk

Adverse event: Aching or soreness in hip joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 27 affected / 53 at risk

Adverse event: Increase in shortness of breath
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 8 affected / 53 at risk

Adverse event: New chest pain
Serious: no
Organ System: General disorders
Frequency: 3 affected / 53 at risk

Adverse event: Fever greater than 101 degrees
Serious: no
Organ System: General disorders
Frequency: 2 affected / 53 at risk

Adverse event: Chills
Serious: no
Organ System: General disorders
Frequency: 15 affected / 53 at risk

Adverse event: New headaches
Serious: no
Organ System: General disorders
Frequency: 19 affected / 53 at risk

Adverse event: Pain in muscles
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 31 affected / 53 at risk

Adverse event: Nausea or vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 17 affected / 53 at risk

Adverse event: New rash
Serious: no
Organ System: General disorders
Frequency: 10 affected / 53 at risk

Adverse event: New swelling in hands or feet
Serious: no
Organ System: General disorders
Frequency: 17 affected / 53 at risk

Adverse event: Pain in bones
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 19 affected / 53 at risk

Adverse event: Other type of blood clotting or thrombosis
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 53 at risk

Adverse event: Cardiovascular event
Serious: yes
Organ System: Cardiac disorders
Frequency: 3 affected / 51 at risk

Adverse event: General event
Serious: yes
Organ System: General disorders
Frequency: 6 affected / 51 at risk

Adverse event: Infection
Serious: yes
Organ System: Infections and infestations
Frequency: 2 affected / 51 at risk

Adverse event: Injury
Serious: yes
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 51 at risk

Adverse event: Dyspnoea
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 51 at risk

Adverse event: Vascular
Serious: yes
Organ System: Vascular disorders
Frequency: 2 affected / 51 at risk

Adverse event: Aching or soreness in feet
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 22 affected / 51 at risk

Adverse event: Aching or soreness in thighs
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 21 affected / 51 at risk

Adverse event: Aching or soreness in lower back
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 32 affected / 51 at risk

Adverse event: Aching or soreness in knee joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 22 affected / 51 at risk

Adverse event: Aching or soreness in other joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 12 affected / 51 at risk

Adverse event: Aching or soreness in calves
Serious: no
Organ System: Vascular disorders
Frequency: 26 affected / 51 at risk

Adverse event: Aching or soreness in buttocks
Serious: no
Organ System: Vascular disorders
Frequency: 14 affected / 51 at risk

Adverse event: Aching or soreness in other areas
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 21 affected / 51 at risk

Adverse event: Aching or soreness in hip joints
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 21 affected / 51 at risk

Adverse event: Increase in shortness of breath
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 11 affected / 51 at risk

Adverse event: New chest pain
Serious: no
Organ System: General disorders
Frequency: 3 affected / 51 at risk

Adverse event: Fever greater than 101 degrees
Serious: no
Organ System: General disorders
Frequency: 3 affected / 51 at risk

Adverse event: Chills
Serious: no
Organ System: General disorders
Frequency: 12 affected / 51 at risk

Adverse event: New headaches
Serious: no
Organ System: General disorders
Frequency: 20 affected / 51 at risk

Adverse event: Pain in muscles
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 28 affected / 51 at risk

Adverse event: Nausea or vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 12 affected / 51 at risk

Adverse event: New rash
Serious: no
Organ System: General disorders
Frequency: 7 affected / 51 at risk

Adverse event: New swelling in hands or feet
Serious: no
Organ System: General disorders
Frequency: 16 affected / 51 at risk

Adverse event: Pain in bones
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 17 affected / 51 at risk

Adverse event: Other type of blood clotting or thrombosis
Serious: no
Organ System: Vascular disorders
Frequency: 1 affected / 51 at risk