TrialPanorama/TrialPanorama-database huggingface dataset:
Study: NCT02034877

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 999 at risk

Adverse event: Vaccination site pain
Serious: no
Organ System: General disorders
Frequency: 46 affected / 999 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 22 affected / 999 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 4 affected / 999 at risk

Adverse event: Chills
Serious: no
Organ System: General disorders
Frequency: 2 affected / 999 at risk

Adverse event: Vaccination site erythema
Serious: no
Organ System: General disorders
Frequency: 2 affected / 999 at risk

Adverse event: Vaccination site nodule
Serious: no
Organ System: General disorders
Frequency: 2 affected / 999 at risk

Adverse event: Malaise
Serious: no
Organ System: General disorders
Frequency: 1 affected / 999 at risk

Adverse event: Vaccination site induration
Serious: no
Organ System: General disorders
Frequency: 1 affected / 999 at risk

Adverse event: Viral infection
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 999 at risk

Adverse event: Decreased appetite
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 999 at risk

Adverse event: Joint range of motion decreased
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 9 affected / 999 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 4 affected / 999 at risk

Adverse event: Myalgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 4 affected / 999 at risk

Adverse event: Limb discomfort
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 999 at risk

Adverse event: Pain in extremity
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 999 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 999 at risk

Adverse event: Chronic obstructive pulmonary disease
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 999 at risk

Adverse event: Cough
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 999 at risk

Adverse event: Drug eruption
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 999 at risk
Study: NCT02035202

Adverse event: Hospitalisation
Serious: no
Organ System: Psychiatric disorders
Frequency: 10 affected / 85 at risk

Adverse event: Hospitalisation
Serious: no
Organ System: Psychiatric disorders
Frequency: 12 affected / 85 at risk

Adverse event: Hospitalisation
Serious: no
Organ System: Psychiatric disorders
Frequency: 9 affected / 85 at risk
Study: NCT02035332

Adverse event: Surgery for Heart Valve Replacement
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 21 at risk

Adverse event: Anesthesia Related
Serious: no
Organ System: Surgical and medical procedures
Frequency: 6 affected / 21 at risk

Adverse event: Haemorrhage
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 6 affected / 21 at risk

Adverse event: Pelvic Cramping (non-specific)
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 9 affected / 21 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 21 at risk

Adverse event: Back pain-occasional in middle-back
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 21 at risk

Adverse event: pregnancy- empty sac
Serious: no
Organ System: Pregnancy, puerperium and perinatal conditions
Frequency: 1 affected / 21 at risk

Adverse event: Chest pain
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 21 at risk

Adverse event: Asthenia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 21 at risk
Study: NCT02035345

Adverse event: Anaphylactic reaction
Serious: yes
Organ System: Immune system disorders
Notes: Anaphylaxis is considered a serious adverse event (or very severe hypersensitivity reaction)
Frequency: 1 affected / 15 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 15 at risk

Adverse event: Hypersensitivity
Serious: no
Organ System: Immune system disorders
Frequency: 5 affected / 15 at risk

Adverse event: Hypokalaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 15 at risk
Study: NCT02035475

Adverse event: Rehospitalization
Serious: yes
Organ System: General disorders
Notes: Rehospitalization due to fever and back pain.
Frequency: 1 affected / 114 at risk

Adverse event: Bilateral Pulmonary Embolisms
Serious: yes
Organ System: Blood and lymphatic system disorders
Notes: Shortness of breath. ER visit-CT angioplasty with thrombolysis and IVC filter placement with extended hospital (2 day) stay.
Frequency: 1 affected / 114 at risk

Adverse event: Prolonged existing hospitalization
Serious: yes
Organ System: General disorders
Notes: Post-operative course complicated by syncope (likely vasovagal in context of pain), SOB, Ileus.
Frequency: 2 affected / 114 at risk
Study: NCT02036294

Adverse event: Hospitalization for any cause
Serious: yes
Organ System: General disorders
Notes: These events are hospitalizations of any cause that occurred during the study period (between study enrollment and 6 months). These are anticipated adverse events.
Frequency: 69 affected / 120 at risk

Adverse event: Hospitalization for any cause
Serious: yes
Organ System: General disorders
Notes: These events are hospitalizations of any cause that occurred during the study period (between study enrollment and 6 months). These are anticipated adverse events.
Frequency: 76 affected / 120 at risk
Study: NCT02036424

Adverse event: Vitreous haemorrhage
Serious: yes
Organ System: Eye disorders
Frequency: 2 affected / 23 at risk

Adverse event: cranial nerve VI palsy
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 23 at risk

Adverse event: Bradycardia
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 23 at risk

Adverse event: Pneumonia
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 23 at risk

Adverse event: Pyelonephritis
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 23 at risk

Adverse event: Colon cancer
Serious: yes
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 23 at risk

Adverse event: Vitreous degeneration
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 23 at risk

Adverse event: Posterior capsule opacification
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 23 at risk

Adverse event: Vitreous haemorrhage
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 23 at risk

Adverse event: worsening of cataract
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 23 at risk

Adverse event: Vitreous haemorrhage
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 22 at risk

Adverse event: Choroidal detachment
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 22 at risk

Adverse event: Cardiac failure congestive
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 22 at risk

Adverse event: Epiretinal membrane
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 27 at risk

Adverse event: Vitreous degeneration
Serious: no
Organ System: Eye disorders
Frequency: 3 affected / 27 at risk

Adverse event: Posterior capsule opacification
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 27 at risk

Adverse event: Vitreous haemorrhage
Serious: no
Organ System: Eye disorders
Frequency: 2 affected / 27 at risk

Adverse event: worsening of cataract
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 27 at risk

Adverse event: Intraocular pressure increased
Serious: no
Organ System: Eye disorders
Frequency: 14 affected / 27 at risk
Study: NCT02036541

Adverse event: Explant
Serious: yes
Organ System: Eye disorders
Frequency: 1 affected / 65 at risk

Adverse event: Secondary glaucoma procedure with explant
Serious: yes
Organ System: Eye disorders
Frequency: 6 affected / 65 at risk

Adverse event: Secondary glaucoma procedure
Serious: yes
Organ System: Eye disorders
Frequency: 2 affected / 65 at risk

Adverse event: Hypotony (IOP < 6 mmHg)
Serious: no
Organ System: Eye disorders
Notes: All IOP \< 6 mmHg was recorded as an adverse event, regardless of whether there were any associated complications or sequelae related to the low pressure. No clinically-significant consequences were associated with these hypotony cases
Frequency: 16 affected / 65 at risk

Adverse event: IOP increase ≥ 10 mmHg from baseline
Serious: no
Organ System: Eye disorders
Frequency: 14 affected / 65 at risk

Adverse event: Needling procedure
Serious: no
Organ System: Eye disorders
Notes: The protocol required these procedures to be recorded as adverse events
Frequency: 21 affected / 65 at risk

Adverse event: Wound dehiscence/leak
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 65 at risk

Adverse event: Wound repair
Serious: no
Organ System: Eye disorders
Frequency: 5 affected / 65 at risk

Adverse event: Anterior chamber tap
Serious: no
Organ System: Eye disorders
Frequency: 6 affected / 65 at risk

Adverse event: Best-Corrected Visual Acuity Loss of ≥ 2 lines ≤ 30 days postop
Serious: no
Organ System: Eye disorders
Frequency: 10 affected / 65 at risk

Adverse event: Best-Corrected Visual Acuity loss of ≥ 2 lines > 30 days
Serious: no
Organ System: Eye disorders
Frequency: 7 affected / 65 at risk

Adverse event: Best-Corrected Visual Acuity loss of ≥ 2 lines at 12 Months
Serious: no
Organ System: Eye disorders
Frequency: 4 affected / 65 at risk
Study: NCT02036840

Adverse event: Urticaria
Serious: no
Organ System: Immune system disorders
Frequency: 4 affected / 513 at risk

Adverse event: Erythema
Serious: no
Organ System: Immune system disorders
Frequency: 1 affected / 513 at risk

Adverse event: Rash
Serious: no
Organ System: Immune system disorders
Frequency: 6 affected / 513 at risk

Adverse event: Hypotension
Serious: no
Organ System: General disorders
Frequency: 1 affected / 513 at risk
Study: NCT02037165

Adverse event: Sinus bradycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 3 affected / 25 at risk

Adverse event: Sinus bradycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 2 affected / 24 at risk

Adverse event: Sinus bradycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 3 affected / 25 at risk

Adverse event: Sinus bradycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 2 affected / 25 at risk

Adverse event: Sinus bradycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 5 affected / 25 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 8 affected / 25 at risk

Adverse event: Dizziness
Serious: no
Organ System: Nervous system disorders
Frequency: 9 affected / 25 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 25 at risk
Study: NCT02037204

Adverse event: Post surgery (joint swelling, pain)
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 18 affected / 35 at risk
Study: NCT02037256

Adverse event: Dyspnoea
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 6 at risk

Adverse event: Tachycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 6 at risk

Adverse event: Hypocalcaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 6 at risk

Adverse event: Hyperuricaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 6 at risk

Adverse event: Infection 1
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 6 at risk

Adverse event: Febrile neutropenia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 17 at risk

Adverse event: Hypertensive crisis
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 17 at risk

Adverse event: Mucosal inflammation
Serious: no
Organ System: Immune system disorders
Frequency: 1 affected / 17 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 17 at risk

Adverse event: Hypocalcaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 17 at risk

Adverse event: Low ionized calcioum
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 1 affected / 17 at risk

Adverse event: Hypokalaemia
Serious: no
Organ System: Blood and lymphatic system disorders
Frequency: 3 affected / 17 at risk

Adverse event: Infection 1
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 17 at risk

Adverse event: Infection 2
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 17 at risk
Study: NCT02037347

Adverse event: ischemic necrosis
Serious: yes
Organ System: Gastrointestinal disorders
Notes: ischemic necrosis of the small bowel
Frequency: 1 affected / 1 at risk
Study: NCT02037425

Adverse event: Dizziness
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 44 at risk

Adverse event: Aphasia
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 44 at risk

Adverse event: Gait disturbance
Serious: yes
Organ System: Nervous system disorders
Frequency: 1 affected / 44 at risk

Adverse event: Abortion spontaneous
Serious: yes
Organ System: Pregnancy, puerperium and perinatal conditions
Frequency: 1 affected / 44 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 44 at risk

Adverse event: Bronchitis
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 4 affected / 44 at risk

Adverse event: Eyebrow Droop
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 3 affected / 44 at risk

Adverse event: Eyebrow Heaviness
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 44 at risk

Adverse event: Neck pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 2 affected / 44 at risk

Adverse event: Sinusitis
Serious: no
Organ System: Infections and infestations
Frequency: 2 affected / 44 at risk

Adverse event: Strep Throat
Serious: no
Organ System: Infections and infestations
Frequency: 4 affected / 44 at risk

Adverse event: Upper respiratory tract infection
Serious: no
Organ System: Infections and infestations
Frequency: 3 affected / 44 at risk

Adverse event: Weight increased
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 4 affected / 44 at risk
Study: NCT02037477

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 10 at risk

Adverse event: Pyrexia
Serious: no
Organ System: General disorders
Frequency: 1 affected / 10 at risk

Adverse event: Rash
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 10 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 10 at risk
Study: NCT02037620

Adverse event: Incision Dehiscence
Serious: yes
Organ System: Surgical and medical procedures
Frequency: 3 affected / 5 at risk

Adverse event: Urinary tract infection
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 1 affected / 5 at risk

Adverse event: Right Knee Fracture
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 5 at risk

Adverse event: Bursitis
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 5 at risk
Study: NCT02037776

Adverse event: Cervix carcinoma
Serious: yes
Organ System: Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Frequency: 1 affected / 63 at risk

Adverse event: Rash
Serious: yes
Organ System: Skin and subcutaneous tissue disorders
Frequency: 1 affected / 63 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 63 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 63 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 63 at risk

Adverse event: Back pain
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Frequency: 1 affected / 63 at risk

Adverse event: Fall
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 63 at risk

Adverse event: Fractures
Serious: no
Organ System: Injury, poisoning and procedural complications
Frequency: 1 affected / 63 at risk

Adverse event: Gingivitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 65 at risk

Adverse event: Nasopharyngitis
Serious: no
Organ System: Infections and infestations
Frequency: 1 affected / 65 at risk

Adverse event: Upper respiratory tract inflammation
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 65 at risk

Adverse event: Oropharyngeal pain
Serious: no
Organ System: Respiratory, thoracic and mediastinal disorders
Frequency: 1 affected / 65 at risk

Adverse event: Abdominal pain upper
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 65 at risk

Adverse event: Constipation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 65 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 65 at risk

Adverse event: Faeces soft
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 65 at risk
Study: NCT02037919

Adverse event: Post abortal endometritis
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 73 at risk

Adverse event: Pregnancy
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 73 at risk

Adverse event: Vomiting
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 75 at risk

Adverse event: Rapid weight loss
Serious: no
Organ System: Metabolism and nutrition disorders
Frequency: 1 affected / 75 at risk
Study: NCT02038075

Adverse event: Suicide death
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 76 at risk

Adverse event: Suicide death
Serious: yes
Organ System: Psychiatric disorders
Frequency: 1 affected / 76 at risk
Study: NCT02038179

Adverse event: Increase Blood Pressure (>= 160 disastolic blood pressure or >=90 systolic blood pressure)
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 99 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 99 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 99 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 3 affected / 99 at risk

Adverse event: Somnolence
Serious: no
Organ System: General disorders
Frequency: 1 affected / 99 at risk

Adverse event: Pruritus
Serious: no
Organ System: General disorders
Frequency: 1 affected / 99 at risk

Adverse event: Abnormal Menses
Serious: no
Organ System: Reproductive system and breast disorders
Frequency: 1 affected / 99 at risk

Adverse event: Weight increased
Serious: no
Organ System: General disorders
Frequency: 1 affected / 99 at risk

Adverse event: Elevated Liver Enzyme
Serious: no
Organ System: Hepatobiliary disorders
Frequency: 1 affected / 99 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 99 at risk

Adverse event: Tachycardia
Serious: no
Organ System: Cardiac disorders
Frequency: 1 affected / 99 at risk

Adverse event: Diarrhoea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 2 affected / 99 at risk

Adverse event: Hyper-defecation
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 1 affected / 99 at risk

Adverse event: Dizziness
Serious: no
Organ System: Ear and labyrinth disorders
Frequency: 1 affected / 99 at risk

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 99 at risk

Adverse event: Fatigue
Serious: no
Organ System: General disorders
Frequency: 1 affected / 99 at risk

Adverse event: Pruritus
Serious: no
Organ System: General disorders
Frequency: 1 affected / 99 at risk

Adverse event: Leukopenia
Serious: no
Organ System: Blood and lymphatic system disorders
Notes: Reduced white blood cell count
Frequency: 1 affected / 99 at risk

Adverse event: Nausea
Serious: no
Organ System: Gastrointestinal disorders
Frequency: 3 affected / 99 at risk
Study: NCT02038218

Adverse event: Headache
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 22 at risk

Adverse event: Seizure
Serious: no
Organ System: Nervous system disorders
Frequency: 2 affected / 22 at risk

Adverse event: Seizure
Serious: no
Organ System: Nervous system disorders
Frequency: 1 affected / 7 at risk
Study: NCT02038452

Adverse event: Other
Serious: yes
Organ System: Cardiac disorders
Notes: Cardiac failure NB No specific adverse event term for this AE in CTCAE 4.0. Adverse event recorded as 'other' \& AE Term Additional Description provided, aligning with trial EudraCT entry.
Frequency: 1 affected / 116 at risk

Adverse event: Other
Serious: yes
Organ System: Respiratory, thoracic and mediastinal disorders
Notes: Cryptogenic organising pneumonia NB No specific adverse event term for this AE in CTCAE 4.0. Adverse event recorded as 'other' \& AE Term Additional Description provided, aligning with trial EudraCT entry.
Frequency: 1 affected / 116 at risk

Adverse event: Other
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Patella resurfacing NB No specific adverse event term for this AE in CTCAE 4.0. Adverse event recorded as 'other' \& AE Term Additional Description provided, aligning with trial EudraCT entry.
Frequency: 1 affected / 116 at risk

Adverse event: Flushing
Serious: no
Organ System: Vascular disorders
Frequency: 17 affected / 116 at risk

Adverse event: Other
Serious: no
Organ System: Skin and subcutaneous tissue disorders
Notes: Thinning, lightening or darkening of skin at injection site
Frequency: 4 affected / 116 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: For steroid injection, hand or wrist was more painful following injection. For splinting, participants unable to wear splint because of discomfort.
Frequency: 53 affected / 116 at risk

Adverse event: Fracture
Serious: yes
Organ System: Injury, poisoning and procedural complications
Notes: Open comminuted fracture left middle finger, operative fixation with K-wires
Frequency: 1 affected / 118 at risk

Adverse event: Myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 118 at risk

Adverse event: Arthritis
Serious: yes
Organ System: Musculoskeletal and connective tissue disorders
Notes: Total arthroplasty for osteoarthritis (one hip, one knee)
Frequency: 2 affected / 118 at risk

Adverse event: Arthralgia
Serious: no
Organ System: Musculoskeletal and connective tissue disorders
Notes: For steroid injection, hand or wrist was more painful following injection. For splinting, participants unable to wear splint because of discomfort.
Frequency: 7 affected / 118 at risk