Study: NCT02673697

Adverse event: Myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 6 affected / 450 at risk

Adverse event: Cerebrovascular accident
Serious: yes
Organ System: Nervous system disorders
Frequency: 21 affected / 450 at risk

Adverse event: Aortic valve re-intervention
Serious: yes
Organ System: Cardiac disorders
Frequency: 13 affected / 450 at risk

Adverse event: Transient ischaemic attack
Serious: yes
Organ System: Nervous system disorders
Frequency: 7 affected / 450 at risk

Adverse event: Haemorrhage
Serious: yes
Organ System: Vascular disorders
Frequency: 30 affected / 450 at risk

Adverse event: Acute kidney injury
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 10 affected / 450 at risk

Adverse event: Endocarditis
Serious: yes
Organ System: Cardiac disorders
Frequency: 11 affected / 450 at risk

Adverse event: Prosthetic cardiac valve malfunction
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 450 at risk

Adverse event: Valve thrombosis
Serious: yes
Organ System: Cardiac disorders
Frequency: 2 affected / 450 at risk

Adverse event: Arrhythmia or conduction disorder
Serious: yes
Organ System: Cardiac disorders
Frequency: 100 affected / 450 at risk

Adverse event: Thromboembolic event, non-cerebral
Serious: yes
Organ System: Vascular disorders
Frequency: 3 affected / 450 at risk

Adverse event: Thrombocytopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 11 affected / 450 at risk

Adverse event: Major vascular complication
Serious: yes
Organ System: Vascular disorders
Frequency: 3 affected / 450 at risk

Adverse event: Other cardiovascular SAE
Serious: yes
Organ System: Vascular disorders
Frequency: 39 affected / 450 at risk

Adverse event: Other non-cardiovascular SAE
Serious: yes
Organ System: General disorders
Frequency: 132 affected / 450 at risk

Adverse event: Myocardial infarction
Serious: yes
Organ System: Cardiac disorders
Frequency: 15 affected / 446 at risk

Adverse event: Cerebrovascular accident
Serious: yes
Organ System: Nervous system disorders
Frequency: 16 affected / 446 at risk

Adverse event: Aortic valve re-intervention
Serious: yes
Organ System: Cardiac disorders
Frequency: 7 affected / 446 at risk

Adverse event: Transient ischaemic attack
Serious: yes
Organ System: Nervous system disorders
Frequency: 4 affected / 446 at risk

Adverse event: Haemorrhage
Serious: yes
Organ System: Vascular disorders
Frequency: 39 affected / 446 at risk

Adverse event: Acute kidney injury
Serious: yes
Organ System: Renal and urinary disorders
Frequency: 13 affected / 446 at risk

Adverse event: Endocarditis
Serious: yes
Organ System: Cardiac disorders
Frequency: 15 affected / 446 at risk

Adverse event: Prosthetic cardiac valve malfunction
Serious: yes
Organ System: Cardiac disorders
Frequency: 1 affected / 446 at risk

Adverse event: Arrhythmia or conduction disorder
Serious: yes
Organ System: Cardiac disorders
Frequency: 76 affected / 446 at risk

Adverse event: Thromboembolic event, non-cerebral
Serious: yes
Organ System: Vascular disorders
Frequency: 4 affected / 446 at risk

Adverse event: Thrombocytopenia
Serious: yes
Organ System: Blood and lymphatic system disorders
Frequency: 2 affected / 446 at risk

Adverse event: Major vascular complication
Serious: yes
Organ System: Vascular disorders
Frequency: 3 affected / 446 at risk

Adverse event: Other cardiovascular SAE
Serious: yes
Organ System: Vascular disorders
Frequency: 26 affected / 446 at risk

Adverse event: Other non-cardiovascular SAE
Serious: yes
Organ System: General disorders
Frequency: 121 affected / 446 at risk