Please assess the completion status of the following clinical trial:

Trial Title: Noninferiority Comparison of Prophylactic Open Fracture Antimicrobial Regimens

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: PARALLEL
- Observational Model: None
- Primary Purpose: PREVENTION
- Time Perspective: None
- Masking: NONE
- Phase: PHASE4
- Number of Arms: 5.0

Eligibility Criteria:
Inclusion Criteria:~* Age great than/equal to 18 years~* Diagnosis of Grade III open fracture~Exclusion Criteria:~* Water-borne injury~* Farm-related injury

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- Cefazolin + Gentamicin (Type: ACTIVE_COMPARATOR): \[Cefazolin\]~Initial dose:~* Cefazolin 2g IV x1 dose (patient weight \< 120kg)~* Cefazolin 3g IV x1 dose (patient weight \>/= 120kg)~Subsequent dose:~* Cefazolin 2g IV every 8 hrs (CrCl \>/= 40 mL/min)~* Cefazolin 2g IV every 12 hrs (CrCl 20-39 mL/min)~* Cefazolin 2g IV every 24 hrs (CrCl \< 20 mL/min)~Duration:~* 24 hrs post-op after soft tissue coverage or total of 72 hrs, whichever comes first~\[Gentamicin\]~Initial dose:~* If Patient age \</= 80 years old: 5 mg/kg adjusted body weight x1 dose (Max dose 500 mg)~* If Patient age \>80 years old: 3 mg/kg adjusted body weight x1 dose (Max dose 300 mg)~Subsequent dose:~* Pharmacy Consult to dose gentamicin~Duration:~* 24 hrs post-op after soft tissue coverage or total of 72 hrs, whichever comes first
- Ceftriaxone (Type: ACTIVE_COMPARATOR): Initial dose:~* Ceftriaxone 2g IV x1 dose~Subsequent dose:~* Ceftriaxone 2g IV every 24 hours~Duration:~* One dose post-op after soft tissue coverage or total of 72 hours, whichever comes first
- Ampicillin/Sulbactam (Type: ACTIVE_COMPARATOR): Initial dose:~* Ampicillin/Sulbactam 3g IV x1 dose~Subsequent dose:~* Ampicillin/Sulbactam 3g IV every 6 hours (CrCl \>/= 30 mL/min)~* Ampicillin/Sulbactam 3g IV every 12 hours (CrCl 15-29 mL/min)~* Ampicillin/Sulbactam 3g IV every 24 hours (CrCl \<15 mL/min)~Duration:~* 24 hours post-op after soft tissue coverage or total of 72 hours, whichever comes first
- Piperacillin/Tazobactam (Type: ACTIVE_COMPARATOR): Initial dose:~* Piperacillin/Tazobactam 4.5g IV x1 dose over 30 minutes~Subsequent dose:~* Piperacillin/Tazobactam 3.375g IV every 8 hours over 4 hours (CrCl \>/= 20 mL/min)~* Piperacillin/Tazobactam 3.375g IV every 12 hours over 4 hours (CrCl \< 20 mL/min)~Duration:~* 24 hours post-op after soft tissue coverage or total of 72 hours, whichever comes first
- Clindamycin + Gentamicin (Type: OTHER): Patients with known Penicillin allergy will receive:~\[Clindamycin\]~Initial dose:~* Clindamycin 900mg IV x1 dose~Subsequent dose:~* Clindamycin 600mg IV every 8 hours~Duration:~* 24 hours post-op after soft tissue coverage or total of 72 hours, whichever comes first~\[Gentamicin\]~Initial dose:~* If Patient age \</= 80 years old: 5 mg/kg adjusted body weight x1 dose (Max dose 500 mg)~* If Patient age \>80 years old: 3 mg/kg adjusted body weight x1 dose (Max dose 300 mg)~Subsequent dose:~* Pharmacy Consult to dose gentamicin~Duration:~* 24 hours post-op after soft tissue coverage or total of 72 hours, whichever comes first

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: terminate
termination_type: enrollment issues