Please assess the completion status of the following clinical trial:

Trial Title: Study of Placebo Without Deception Versus Standard Antidepressant for Major Depressive Disorder

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: PARALLEL
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: SINGLE
- Phase: None
- Number of Arms: 3.0

Eligibility Criteria:
Inclusion Criteria:~* Provision of written informed consent~* Diagnosis of major depressive disorder, currently depressed as determined by DSM-IV diagnostic criteria (confirmed using the MINI)~* Both females and males, aged 18 to 65 years~* Outpatient status~* Female patients of childbearing potential must have a negative urine human chorionic gonadotropin (hCG) test at enrolment and must be taking or willing to take some acceptable form of birth control during the course of the study if they are or plan to be sexually active~* A grade 8 English comprehension, the ability to understand and comply with the requirements of the study and capable of providing informed consent~* 17-item Hamilton Depression Rating Scale (HAM-D) score of 14-22 at screening and at baseline~Exclusion Criteria:~* Diagnosis of a past hypomanic, manic or mixed state.~* Current or past psychotic symptoms~* Substance or alcohol dependence at enrolment (except dependence in full remission, and except for caffeine or nicotine dependence), as defined by DSM-IV criteria~* Opiates, amphetamine, barbiturate, cocaine, cannabis, or hallucinogen abuse by DSM-IV criteria within 4 weeks prior to enrolment~* Any pervasive developmental disorder (according to DSM-IV criteria)~* Diagnosis of dementia (according to DSM-IV criteria)~* Is at significant risk for suicide, as defined by a score of ≥ 2 on the suicide item of the MADRS, any suicidal ideation with intent or a plan within the 3 months prior to study entry or in the opinion of the investigator.~* Any history of lifetime suicide attempts~* Current treatment with an antidepressant medication~* Treatment with an antipsychotic, mood stabilizer or other psychoactive medication within a period of 5 half-lives of the medication prior to baseline visit~* Known intolerance, hypersensitivity or lack of response to duloxetine as judged by the investigator~* A history of treatment resistant depression (defined as 2 or more failed lifetime trials of antidepressant medication as judged by the investigator)~* Currently undergoing psychotherapy that was initiated within the past 3 months~* Significant medical condition that would contraindicate the use of duloxetine or that is untreated and would need urgent attention (as determined by treating physician)~* Medical conditions that would significantly affect absorption, distribution, metabolism, or excretion of duloxetine~* Unstable or inadequately treated medical illness (e.g. congestive heart failure, angina pectoris, hypertension) as judged by the investigator~* Any clinically significant deviation from the reference range in clinical laboratory test results as judged by the investigator~* Pregnancy (or female of child-bearing age not using adequate contraception) or lactation~* A positive β-hCG test at enrolment~* Involvement in the planning and conduct of the study~* Previous enrolment or randomisation of treatment in the present study~* Participation in another drug trial within 4 weeks prior enrolment into this study or longer in accordance with local requirements

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: 65 Years
- Healthy Volunteers: f

Study Arms:
- Open-label duloxetine (Type: EXPERIMENTAL): 12 week treatment with duloxetine
- Open-label Placebo (Type: EXPERIMENTAL): 4 weeks of open label placebo with option to continue or switch to duloxetine for remaining 8 weeks.
- Supportive clinical management (Type: EXPERIMENTAL): 4 weeks of supportive clinical management visits with option to continue or switch to duloxetine for remaining 8 weeks.

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: terminate
termination_type: enrollment issues