Please assess the completion status of the following clinical trial:

Trial Title: PReventing EXtubation FAILure Related to Cough

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: PARALLEL
- Observational Model: None
- Primary Purpose: PREVENTION
- Time Perspective: None
- Masking: NONE
- Phase: None
- Number of Arms: 2.0

Eligibility Criteria:
Inclusion Criteria:~1. Patients older than 18 years~2. Patients intubated for more than 24h before the extubation attempt~3. Patients able to follow simple commands (M6 response at the GCS) and to provide a signed agreement (or, in case of neurological impairment, to confirm to a third person their will to be included in the study by their appropriate code).~4. Successful weaning trial with a low pressure support (7 cmH2O) during 30-60 min or longer in case of neuromuscular disorders and with PEEP=0 cmH2O~5. Patients included for their first extubation attempt after a successful weaning trial based on classic weaning criteria (with the exception of: self-extubation, accidental extubation, extubation after less than 24 hours of ventilation).~6. No decision of care limitation on respiratory failure (reintubation considered).~7. Informed consent form signed by the patient (if cognitive capacities are preserved despite intubation) or by relatives (if cognitive and judgment capacities are impaired but with a capacity to respond to instructions sufficient to carry out spirometric measurements).~8. Randomisation if the cough is objectively assessed as weak (CPF \< 60 L/min et VT \< 0.55 L). In other case, the patient with a strong cough are only included in an observational study with an outcome assessment.~Exclusion Criteria:~1. Patient with tracheostomy~2. Weaning trial conducted without a pressure support technique during the last test~3. Failure of a weaning trial using a pressure support technique~4. Decision not to extubate after a successful weaning trial~5. Extubation of a patient already included after a previous extubation~6. Final extubation~7. Patients not affiliated to French health care system~8. Patients in poor medical condition (hemodynamic, respiratory instability)~9. Patients moribund or with previous decision of care limitation~10. Absence of informed consent document or patient under legal protection~11. Any clinical argument for a laryngeal oedema~12. No possibility of CPF assessment: ventilator non-adapted for assessment, no comprehension of the cough order despite a M6 response at the GCS (no coughing effort initiated).~13. Patient previously using a mechanical cough assistance~14. Deglutition disorders objectified or supposed (severe lesion of the brainstem), with a theoretical risk of tracheostomy~15. Contra-indication to mechanical cough assistance: pneumothorax or any lesion at risk of pneumothorax (such as costal fracture, emphysema, previous pneumothorax or other barotraumatism)~16. Contra-indication to Non-Invasive Ventilation: agitation, non-treated pneumothorax, thoracic wound, severe vomiting, active digestive haemorrhage with hematemesis, severe cranio-facial traumatism with pneumo-encephaly

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- Intervention group on cough and ventilation assistance (Type: EXPERIMENTAL): Mechanical cough assistance during physiotherapy post-extubation in ICU and systematic indication of NIV.
- Control group on cough and ventilation assistance (Type: OTHER): Control group of extubated patients receiving the current gold standard strategy during physiotherapy after extubation in ICU and with selected indications of NIV.

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: terminate
termination_type: lack of efficacy