Please assess the completion status of the following clinical trial:

Trial Title: AvidinOX + [177Lu]DOTA-biotin (or 177Lu-ST2210) Complex in Patients With Liver Metastases From Colorectal Cancer

Study Design Characteristics:
- Allocation: None
- Intervention Model: SINGLE_GROUP
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: NONE
- Phase: PHASE1
- Number of Arms: 1.0

Eligibility Criteria:
Inclusion Criteria:~1. Male or female ≥ 18 years of age~2. Liver metastases from histologically confirmed colorectal cancer and at least one liver metastasis ≥ 1 cm (measurable disease), which is chemo-resistant, not eligible for curative surgery and suitable for intra-lesional injection as assessed by the investigator.~3. Total liver tumor burden requiring ≤ 75 ml AvidinOX~4. Maximum of 9 liver metastases~5. Eastern Cooperative Oncology Group (ECOG) performance status of ≤ 2~6. Life expectancy of at least 3 months.~7. Clotting parameters as follows, with local normal ranges to be taken as reference:~   * Prothrombin Time (Quick).Patients showing an increase of the Upper Limit of the Normal (ULN) range of about 20% can also be considered for inclusion.~  * International Normalised Ratio (INR). Patients showing an increase of the ULN of about 20% can also be considered for inclusion~  * Activated Partial Thromboplastin Time (aPTT). Patients showing an increase of the ULN of about 20% can also be considered for inclusion~  * Fibrinogen. Patients showing a decrease of the Lower Limit of the Normal range (LLN) of about 20% can also be considered for inclusion.~8. Haematological, liver and renal function test results ≤ grade 2 toxicity (according to US National Cancer Institute's Common Terminology Criteria for Adverse Events v4.03 \[CTCAE\]), i.e.:~   * Haematology:~     * Haemoglobin ≥ 8 g/dl~    * White blood cell count ≥ 2 x 109/L~    * Platelets ≥ 80x 109/L~  * Liver:~     * Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST), Alkaline Phosphatase (AP) ≤ 5 times upper limit of normal~    * Bilirubin ≤ 3 times upper limit of normal~  * Renal:~     * Urine protein dipstick: 0~    * estimated Glomerular Filtration Rate (eGFR)\> 30 ml/min/1.73 m2 (with CKD-EPI formula)~9. Written informed consent~Exclusion Criteria:~1. Known hypersensitivity to Avidin or AvidinOX (e.g. hen egg)~2. Known hypersensitivity to ST2210(DOTA biotin) or any excipient.~3. Life limiting metastases outside the liver. Metastases outside the liver are allowed only in case the residual metastases (after liver treatment) are amenable to further treatments (e.g. surgical removal)~4. Presence of unreachable (e.g. located in a region in the liver that cannot be reached by needle, or too close to major blood vessels or adjacent to main organs) or untreatable hepatic lesions so that the benefit from the treatment of the treatable lesions does not justify patient's inclusion~5. Active infection at screening or history of severe infection within the previous 3 months, if clinically relevant at screening as considered by the investigator~6. Known human immunodeficiency virus (HIV) positive serology or chronically active hepatitis B or C.~7. Administration of another investigational medicinal product within 30 days before the screening period.~8. Previous treatment with Selective Internal Radiation Therapy (SIRT) spheres or any radiopharmaceutical within a period corresponding to 8 half-lives of the radionuclide used for labeling the respective radiopharmaceutical prior to the administration of study drug.~9. Women of child-bearing potential. A permanent postmenopausal status must be proven as follows: history of hysterectomy or hormone analysis in serum: estradiol \< 20 pg/ml and follicle stimulating hormone (FSH) \> 40 IU/L, or amenorrhea starting at least 1 year prior to the study start andnegativeβHCG .~10. Men unwilling to use appropriate contraceptive methods during the study and up to six months after the end of the study~11. Inability or unwillingness to be catheterized~12. History of somatic or psychiatric disease/condition that may interfere with the objectives of the study~13. Clinically significant illness or clinically relevant trauma within 15 days before the screening period~14. Patient who underwent chemotherapy, radiation therapy within 15 days before the screening period

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: 75 Years
- Healthy Volunteers: f

Study Arms:
- AvidinOX/ST2210 (Type: EXPERIMENTAL): AvidinOX/ST2210 - vial containing 22.5 mg AvidinOX + vials containing 10 ml of water for injection (WFI) for the reconstitution in a clear solution with an AvidinOX concentration of 3 mg/ml. One Intralesion administration of a volume of reconstituted AvidinOX equal to 15 % of the lesion volume followed by intravenous infusion of 177Lu-ST2210 Diagnostic dose : 10 ml, 250 MBq±10%177Lu, approximately 1 mg ST2210, 100 mg/mL ascorbic acid, followed by intravenous infusion of a therapeutic dose: 25 ml, escalating 177Lu dose starting at 5 Gigabequerel (GBq) ±10%with escalation steps of 2.5 GBq up to 15 GBq ±10%, approximately 1 mg ST2210, 100 mg/ml ascorbic acid

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: terminate
termination_type: enrollment issues