Please assess the completion status of the following clinical trial:

Trial Title: Avastin and Temsirolimus Following Tyrosine Kinase Inhibitor Failure in Patients With Advanced Renal Cell Carcinoma

Study Design Characteristics:
- Allocation: None
- Intervention Model: SINGLE_GROUP
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: NONE
- Phase: PHASE2
- Number of Arms: 1.0

Eligibility Criteria:
Inclusion Criteria:~* Histologically confirmed renal cell carcinoma in either primary or metastatic lesions. Non-clear histology will be allowed.~* Disease progression on a VEGF-targeted tyrosine kinase inhibitor as the most recent therapy or have experienced intolerable toxicity so as require discontinuation. Only one prior VEGF-targeted tyrosine kinase inhibitor.~* Must be off of VEGF-targeted tyrosine kinase inhibitor for 2 weeks or greater.~* One measurable lesion which is not curable by standard radiation therapy or surgery.~* The enrolling site must agree to obtain paraffin-embedded tumor blocks or at least 10 unstained, paraffin-embedded slides for submission for correlative studies.~* 18 years of age or older~* ECOG Performance Status of 0 or 1~* Baseline laboratory values as outlined in the protocol~* Life expectancy of greater than 3 months~* No prior malignancy diagnosed within the past three years, other than superficial basal cell and superficial squamous cell, or carcinoma in situ of the cervix.~Exclusion Criteria:~* Known CNS disease, except for treated brain metastases~* Previously treated with avastin or mTOR inhibitors~* Other then VEFG-targeted TKI, patients may only have had prior immunotherapy or chemotherapy for stage IV disease~* History of allergic reaction to Chinese hamster ovary cell products, other recombinant antibodies, or compounds of similar chemical or biologic composition to avastin or temsirolimus~* History of bleeding diathesis or coagulopathy. Therapeutic anticoagulants are allowed~* Patients with clinically significant cardiovascular disease~* Patients receiving enzyme-inducing antiepileptic drugs or any other CYP3A4 inducer such as rifampin or St. John's wort~* No serious non-healing wound, ulcer or bone fracture~* No uncontrolled intercurrent illness including , but not limited to, ongoing active infection requiring parental antibiotics or psychiatric illness/social situations that would limit compliance with study requirements~* HIV-positive receiving combination anti-retroviral therapy~* Major surgical procedure, open biopsy, or significant traumatic injury within 28 days prior to study enrollment or anticipation of need for major surgical procedure during the course of the study~* Core biopsy or other minor surgical procedure, excluding placement of vascular access device, within 7 days prior to enrollment on study~* History of abdominal fistula, gastrointestinal perforation, or intra-abdominal abscess within 6 months prior to study enrollment~* Known hypersensitivity to any component of avastin or temsirolimus~* Life expectancy of less than 12 weeks~* History of hemoptysis within 1 month prior to day 1

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- bevacizumab and temsirolimus (Type: EXPERIMENTAL): bevacizumab: given intravenously at a dose of 10mg/kg every 2 weeks (days 1 and 15)~temsirolimus: given intravenously at a dose of 25mg weekly on days 1, 8, 15, and 22~1 cycle=28-days~There were no dose reductions for bevacizumab allowed. If bevacizumab was held, the same dose would be used if treatment were resumed. If temsirolimus was held, the same or a reduced dose (15mg IV weekly) could be used upon resumption of therapy. Treatment was continued until the development of unacceptable toxicity or progression.

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: complete