Please assess the completion status of the following clinical trial:

Trial Title: Safety, Tolerability, and Effect of Alirocumab in High Cardiovascular Risk Patients With Severe Hypercholesterolemia Not Adequately Controlled With Conventional Lipid-modifying Therapies (ODYSSEY APPRISE)

Study Design Characteristics:
- Allocation: None
- Intervention Model: SINGLE_GROUP
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: NONE
- Phase: PHASE3
- Number of Arms: 1.0

Eligibility Criteria:
Inclusion criteria:~Either A, B, C, D, or E below and not adequately controlled with a maximally tolerated dose of statin with or without other LMTs, all at stable doses for at least 4 weeks prior to the screening visit (Week-3):~A. Participants suffering from heterozygous familial hypercholesterolemia (heFH) with LDL-C concentrations greater than or equal to (\>=)160 mg/dL (4.14 millimoles per liter \[mmol/L\]) despite treatment.~B. Participants suffering from heFH with LDL-C concentrations \>=130 mg/dL (3.36 mmol/L) despite treatment and two or more CV risk factors among this list:~* LDL-C greater than (\>) 250 milligrams per deciliter (mg/dL) (6.46 mmol/L) at the time of the familial hypercholesterolemia (FH) diagnosis (before treatment).~* Family history of premature-onset coronary heart disease (CHD; first-degree male relative with onset before age 55 years; first-degree female relative with onset before age 65 years).~* Metabolic syndrome.~* HDL-C less than (\<) 40 mg/dL (1.03 mmol/L).~* Hypertension (blood pressure \>140/90 mmHg or drug treatment).~* Lipoprotein a (Lp\[a\]) \>=50 mg/dL (1.78 µmol/L).~* Tendon xanthoma.~C. Participants suffering from heFH with LDL-C concentrations \>=130 mg/dL (3.36 mmol/L) despite treatment and one of the following characteristics:~* Established CHD or other cardiovascular disease (CVD; history of acute myocardial infarction, ischemic stroke, peripheral arterial disease, coronary or peripheral arterial revascularization, stable or unstable angina, transient ischemic attack, carotid artery stenosis \>=50 percent (%), or aortic abdominal aneurysm).~* Drug-treated type 2 diabetes mellitus or type 1 with target organ damage.~* Family history of first- or second-degree relative with very premature onset CHD (first- or second-degree male relative with onset before age 45; first- or second-degree female relative with onset before age 55).~D. Non-FH participants suffering from established CHD or other CVD (history of acute myocardial infarction (MI), ischemic stroke, peripheral arterial disease, coronary or peripheral arterial revascularization, stable or unstable angina, transient ischemic attack, carotid artery stenosis \>=50%, or aortic abdominal aneurysm) and with LDL-C concentrations \>=130 mg/dL (3.36 mmol/L).~E. Participants suffering from progressive CVD (coronary artery disease, or peripheral arterial occlusive disease or cerebrovascular disease as documented clinically or by imaging techniques, with a subsequent CV event \[acute MI, ischemic stroke, ischemia-driven revascularization, unstable angina, transient ischemic attack\] occurring despite stable doses of maximally tolerated LMT) with LDL-C concentrations \>=100 mg/dL (2.59 mmol/L).~Exclusion criteria:~Not on a stable dose of LMT (including statin) for at least 4 weeks prior to the screening visit (Week -3) and from screening to enrollment.~Use of a fibrate other than fenofibrate within 4 weeks of the screening visit (Week-3) or between screening and enrollment.~Daily doses above atorvastatin 80 mg, rosuvastatin 40 mg, or simvastatin 40 mg (except for participants on simvastatin 80 mg for more than one year, who were eligible).~Use of statin other than simvastatin, atorvastatin, or rosuvastatin prior to the screening visit (Week-3) or between screening and enrollment, except when there was a documented reason for intolerance to the above mentioned potent statins (in which case the use of a different statin was allowed).~Fasting serum TG \>400 mg/dL (\>4.52 mmol/L) at the screening visit (Week -3). Uncontrolled hypertension (\>180 mmHg systolic and/or \>110 mmHg diastolic at randomization visit).~New York Heart Association Class III or IV congestive heart failure persisting despite treatment.~History of hemorrhagic stroke. Liver transaminases \>3 times the upper limit of normal. Laboratory evidence of current hepatitis B or C infection. Creatine kinase \>3 times the upper limit of normal. Estimated glomerular filtration rate \<30 mL/min/1.73 m\^2. Pregnant or breastfeeding woman or with childbearing potential without appropriate contraception.~Male participant with a female partner of childbearing potential not protected by a highly-effective method(s) of birth control.~Participants eligible for enrollment into an ongoing clinical study of alirocumab conducted at the same investigational site.~Hypersensitivity to alirocumab or any of the excipients.~The above information was not intended to contain all considerations relevant to a participant's potential participation in a clinical trial.

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- Alirocumab (Type: EXPERIMENTAL): Participants received Alirocumab 150 milligram (mg) subcutaneously (SC) once every two weeks (Q2W) or 75 mg SC Q2W added to stable LMT up to a maximum of 120 weeks. Alirocumab dose was either up-titrated from 75 to 150 mg Q2W or down-titrated from 150 to 75 mg Q2W, based on Investigator judgment and treatment response.

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: complete