Please assess the completion status of the following clinical trial:

Trial Title: Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors

Study Design Characteristics:
- Allocation: None
- Intervention Model: SINGLE_GROUP
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: NONE
- Phase: PHASE1
- Number of Arms: 1.0

Eligibility Criteria:
Inclusion Criteria:~1. Age: ≥ 1 year and ≤ 29 years~2. Relapse or progression of any central nervous system tumor initially diagnosed before the age of 21 years.~3. Total or subtotal resection of tumor mass, confirmed by assessment by the neurosurgeon and by postoperative MRI scan within 72 hours after surgery. The post-operative assessment should demonstrate residual tumor less than or equal to 2 cm\^3 as judged by surgeon or on MRI the tumor should only show linear contrast enhancement at the border of the resection cavity or nodule less than 2 cm\^3.~4. No radiotherapy and/or chemotherapy received for at least 1 month before first DC vaccination is to be administered.~5. No treatment with corticosteroids or salicylates for at least 1 week before first vaccination.~6. Life expectancy ≥ 3 months~7. Written consent by patient or parent(s) (if patient is \< 18 years) on an institutional review board (IRB)-approved informed consent form prior to any study-specific evaluation. Assent is required from children as per University of Miami (UM) IRB guidelines. Subject must be capable of understanding the investigational nature, potential risks and benefits of the study and able to provide valid informed consent.~8. Adequate organ function (to be measured at enrollment)~   * Absolute neutrophil count (ANC) ≥750/L~  * Lymphocytes ≥ 500/L~  * Platelets ≥ 75,000/L~  * Hemoglobin ≥ 9 g/dL~  * Aspartate aminotransferase (AST)/Alanine transaminase (ALT) ≤ 2.5 X upper limit of normal (ULN); if liver metastases, ≤ 5 X ULN~  * Serum Creatinine ≤ 1.5 X ULN~  * Total Bilirubin ≤ 3 X ULN~  * Albumin \> 2 g/dL~9. Subjects must agree to use adequate method of contraception or abstinence throughout and up to 4 weeks after the study treatment completion.~10. Karnofsky score ≥ 70 or Eastern Cooperative Oncology Group (ECOG) status of 0 or 1.~Exclusion Criteria:~1. Pregnancy.~2. Breast feeding females.~3. Any concomitant participation in other therapeutic trials.~4. Virus serology positive for HIV (testing is not required in the absence of clinical suspicion).~5. Documented immunodeficiency or autoimmune disease.~6. Other active malignancies.~7. Refusal to use adequate contraception for fertile patients (females and males) during the study and for 30 days after the last dose of study treatment.~8. Any serious or uncontrolled medical or psychiatric condition that in the opinion of the investigator makes the patient not able to participate in the study.~9. Application of gliadel wafers within the prior 4 months or a plan to place Gliadel wafers at the time of resection for tumor acquisition for study.

- Gender: ALL
- Minimum Age: 1 Year
- Maximum Age: 29 Years
- Healthy Volunteers: f

Study Arms:
- DC Vaccine + Lysate (Type: EXPERIMENTAL): * Leukapheresis: Baseline, post-surgery;~* Dendritic Cell Vaccine (DC Vaccine): Post-Leukapheresis, administered intradermally once weekly via intradermal injection, for 4 weeks for a total of four vaccinations;~* Tumor Lysate (Lysate): Post-DC Vaccine therapy. Administered intradermally during weeks 8, 12, 16, and 28;~* Imiquimod: Self-applied topically by subject before and after scheduled DC Vaccine or Lysate administrations.

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: terminate
termination_type: enrollment issues