Please assess the completion status of the following clinical trial:

Trial Title: Isavuconazole for the Prevention of COVID-19-associated Pulmonary Aspergillosis

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: PARALLEL
- Observational Model: None
- Primary Purpose: PREVENTION
- Time Perspective: None
- Masking: TRIPLE
- Phase: PHASE3
- Number of Arms: 2.0

Eligibility Criteria:
Inclusion Criteria:~* Written informed consent obtained from the patient or his/her legally authorized person.~* Adult patient (\> 18 years).~* PCR-confirmed SARS-CoV-2 based on nasopharyngeal swab (NPS), oropharyngeal swab (OPS), tracheal aspirate (TA), bronchial aspirate (BA), or bronchoalveolar lavage fluid (BALF) within 14 days prior to ICU admission or within 72 hours following ICU admission.~* Radiographic imaging consistent with SARS-CoV-2 infection (e.g. atypical pneumonia, organizing pneumonia, ground glass opacities) or acute respiratory distress syndrome (ARDS) within 7 days of diagnosis of SARS-CoV-2 infection.~* A negative pregnancy test in women of child-bearing age.~* If a woman is of child-bearing age, she must be willing to use an effective method of contraception for 28 days after the final dose of isavuconazole per manufacturer instructions~Exclusion Criteria:~* Anticipated transfer to another medical center that is not a study site within hours of admission to the ICU.~* Pregnancy based on a positive human chorionic gonadotropin (HCG) test from serum or urine.~* Patient who is breastfeeding and unable to discontinue breastfeeding while taking the study drug.~* Patients with a diagnosis of invasive aspergillosis/detection of Aspergillus spp. by culture from sputum, TA, BA, or BALF or positive GM from serum or BALF at time of screening or randomization.~* History of invasive aspergillosis within the prior six months.~* Patients with a known intolerance or hypersensitivity to isavuconazole or other azole agents.~* History of familial short QT syndrome.~* Patients that are being treated with mold-active antifungal agents for invasive aspergillosis or another invasive fungal infection.~* Patients with severe hepatic impairment or liver cirrhosis (Child C) should be excluded from the study unless the treating physicians feel the benefits of treatment outweigh the risks.~* Treatment with Lopinavir/ritonavir for HIV infection.~* Prohibited Medications~* Co-administration with a strong CYP3A4 inhibitor or high-dose ritonavir as they may alter the plasma concentration of isavuconazole.~* Co-administration with a strong CYP3A4 inducer such as rifampin, carbamazepine, St. John's wort, or long acting barbiturates.

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- SOC plus Isavuconazonium sulfate (Type: EXPERIMENTAL): SOC plus intravenous isavuconazonium sulfate 372 mg every 8 hours for 6 doses followed by 372mg once daily for up to 28 days
- SOC plus Placebo (Type: PLACEBO_COMPARATOR): SOC plus intravenous placebo every 8 hours for 6 doses followed by once daily for up to 28 days

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: terminate
termination_type: enrollment issues