Please assess the completion status of the following clinical trial:

Trial Title: Non-opioid Analgesic Combination With Morphine for Postoperative Analgesia.

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: FACTORIAL
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: QUADRUPLE
- Phase: PHASE4
- Number of Arms: 8.0

Eligibility Criteria:
Inclusion Criteria:~* Adults older than 18 years~* Receiving scheduled surgery requiring the use of a PCA to treat postoperative pain~* Patients with a written informed consent~* Patients with a written informed consent for the sub-study on hyperalgesia (patients in the centers concerned)~* Affiliate to a social security system~Exclusion Criteria:~* Allergy to morphine, paracetamol, nefopam or ketoprofen or to any of their excipients~* Absorption of morphine and / or NOA within 24 hours before surgery~* Absorption of methadone within 48 hours before surgery~* History of epilepsy~* Renal insufficiency (creatinin clearance \<30 ml / min MDRD)~* Hepatic insufficiency~* Severe respiratory insufficiency~* Pregnancy or breastfeeding women~* History of seizures~* Symptomatic urethroprostatic disorders~* Angle-closure glaucoma~* Gastrointestinal, cerebrovascular or other evolving bleedings~* Active peptic ulcer or active gastritis~* Severe heart failure~* History of asthma triggered by taking ketoprofen or similar substances~* Disable adult person under guardianship~* Use of nitrous oxide during anesthesia protocol

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- Control group C: Placebo (Type: PLACEBO_COMPARATOR): All patients will receive treatment intraoperatively (IV) in 30 minutes, 60 minutes before the end of the intervention, then postoperatively every 6 hours for 48 hours.
- Group P: Paracetamol (Type: EXPERIMENTAL): All patients will receive treatment intraoperatively (IV) in 30 minutes, 60 minutes before the end of the intervention, then postoperatively every 6 hours for 48 hours.
- Group N: Nefopam (Type: EXPERIMENTAL): All patients will receive treatment intraoperatively (IV) in 30 minutes, 60 minutes before the end of the intervention, then postoperatively every 6 hours for 48 hours.
- Group K: Ketoprofen (Type: EXPERIMENTAL): All patients will receive treatment intraoperatively (IV) in 30 minutes, 60 minutes before the end of the intervention, then postoperatively every 6 hours for 48 hours.
- Group PN: paracetamol and nefopam (Type: EXPERIMENTAL): All patients will receive treatment intraoperatively (IV) in 30 minutes, 60 minutes before the end of the intervention, then postoperatively every 6 hours for 48 hours.
- Group PK: paracetamol and ketoprofen (Type: EXPERIMENTAL): All patients will receive treatment intraoperatively (IV) in 30 minutes, 60 minutes before the end of the intervention, then postoperatively every 6 hours for 48 hours.
- Group NK: nefopam and ketoprofen (Type: EXPERIMENTAL): All patients will receive treatment intraoperatively (IV) in 30 minutes, 60 minutes before the end of the intervention, then postoperatively every 6 hours for 48 hours.
- Group PNK: paracetamol, nefopam and ketoprofen (Type: EXPERIMENTAL): All patients will receive treatment intraoperatively (IV) in 30 minutes, 60 minutes before the end of the intervention, then postoperatively every 6 hours for 48 hours.

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: terminate
termination_type: lack of efficacy