Please assess the completion status of the following clinical trial:

Trial Title: Image Guided Treatment Optimization With Cetuximab for Patients With Metastatic Colorectal Cancer

Study Design Characteristics:
- Allocation: NON_RANDOMIZED
- Intervention Model: PARALLEL
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: NONE
- Phase: PHASE1/PHASE2
- Number of Arms: 2.0

Eligibility Criteria:
Inclusion Criteria:~Subjects are eligible if they meet the following criteria:~* Advanced colorectal adenocarcinoma~* Subjects must have been treated according to standard care with palliative chemotherapy including a fluoropyrimidine (e.g. fluorouracil or capecitabine), irinotecan, and oxaliplatin or had contra-indications to treatment with these drugs.~* No local treatment options~* Life expectancy of at least 12 weeks.~* Age =\> 18 years.~* Histological or cytological documentation of cancer is required.~* Tumor material must be tested wild type for the K-RAS (codon 12, 13, 61, 117, 146) and N-RAS (codon 12, 13, 61, 117, 146) genes.~* Subjects have at least one measurable lesion ≥ 2 cm outside the liver. Lesions must be evaluable by CT or MRI according to Response Evaluation Criteria in Solid Tumors (RECIST 1.1).~* ECOG (Eastern Cooperative Oncology Group) Performance Status of 0, 1 or 2~* Adequate liver and renal functions as assessed by the following laboratory requirements to be conducted within 7 days prior to start of treatment:~  * Total bilirubin ≤ 1.5 times the upper limit of normal~ * ALT (alanine aminotransferase) and AST (aspartate aminotransferase) ≤ 2.5 times upper limit of normal (≤ 5 times upper limit of normal for subjects with liver involvement of their cancer)~ * Serum creatinin ≤ 1.5 times upper limit of normal or a calculated creatinin clearance =\> 50 ml/min~* Signed informed consent must be obtained prior to any study specific procedures.~Exclusion Criteria:~Subjects who meet the following criteria at the time of screening will be excluded:~* Previous exposure to an anti-EGFR therapy~* Significant skin condition interfering with treatment~* Pregnant or breast-feeding subjects. Women of childbearing potential must have a negative pregnancy test performed within 7 days of the start of treatment. Both men and women enrolled in this trial must agree to use adequate barrier birth control measures (e.g., cervical cap, condom, and diaphragm) during the course of the trial. Oral birth control methods alone will not be considered adequate on this study, because of the potential pharmacokinetic interaction between study drug and oral contraceptives. Concomitant use of oral and barrier contraceptives is advised. Contraception is necessary for at least 6 months after receiving study drug.~* Concurrent anticancer chemotherapy, immunotherapy or investigational drug therapy during the study or within 4 weeks of the start of study drug.~* Radiotherapy to the target lesions during study or within 4 weeks of the start of study drug. Palliative radiotherapy will be allowed.~* Major surgery within 28 days of start of study drug.~* Substance abuse, medical, psychological or social conditions that may interfere with the subject's participation in the study or evaluation of the study results.~* Any condition that is unstable or could jeopardize the safety of the subject and their compliance in the study.

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- Standard dose cetuximab (Type: OTHER): Uptake of 89Zr-cetuximab: continue standard dose (500mg/m2 bsa) (standard care)
- Dose escalation cetuximab (Type: EXPERIMENTAL): No 89Zr-cetuximab uptake: dose escalation in a 3x3 cohort design (with maximal 50% dose increase each cohort; with a maximum of 2000 mg/m2 bsa every two weeks)

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: terminate
termination_type: lack of efficacy