Please assess the completion status of the following clinical trial:

Trial Title: BIBW 2992 (Afatinib) for the Treatment of Patients With HER2-positive, Hormone-refractory Prostate Cancer

Study Design Characteristics:
- Allocation: None
- Intervention Model: SINGLE_GROUP
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: NONE
- Phase: PHASE2
- Number of Arms: 1.0

Eligibility Criteria:
Inclusion Criteria:~* Patients must provide written informed consent~* Age ≥ 18 years~* Patients must have histological proven, hormone-refractory prostate cancer~* Patients must have failed prior therapy with docetaxel or must be ineligible for treatment with docetaxel~* Patients must have ECOG performance status ≤ 2~* Patients must not have received any prior therapy targeting EGFR or HER2~* Patients must have adequate bone marrow, renal and hepatic function~* Patients must not have a history of severe heart disease~* Patients must not have had a myocardial infarction within the previous six months~* Patients must have normal left ventricular ejection fraction (LVEF ≥ normal limit of institution)~* Patients must not have symptomatic brain or leptomeningeal metastatic disease~* Patients must have recovered from previous treatment-related adverse effects to National Cancer Institute Common Terminology Criteria for Adverse Events version 3.0 (CTCAE) grade ≤ 1~Exclusion Criteria:~* Prior treatment with EGFR/HER2-targeted small molecules or antibodies, i.e. trastuzumab and/or lapatinib~* Known pre-existing interstitial lung disease~* Radiotherapy, chemotherapy, hormone therapy (with the exception of GnRH agonists), immunotherapy or surgery (other than biopsy) within 4 weeks prior to start of treatment with BIBW2992. GnRH-agonists are allowed at the discretion of the investigator.~* Active brain metastases (defined as stable for \< 4 weeks and/or symptomatic and/or requiring changes of treatment with anticonvulsants or steroids within the past 4 weeks and/or leptomeningeal disease). Patients with known history of brain metastases should undergo a baseline brain image to ensure that the disease is stable.~* Any other current malignancy or malignancy diagnosed within the past five (5) years (other than non-melanomatous skin cancer).~* Significant or recent acute gastrointestinal disorders with diarrhoea as a major symptom, e.g. Crohn's disease, malabsorption or CTC grade ≥ 2 diarrhoea of any aetiology.~* History or presence of clinically relevant cardiovascular abnormalities such as uncontrolled hypertension, congestive heart failure NYHA classification of 3, unstable angina or poorly controlled arrhythmia. Myocardial infarction within 6 months prior to randomisation.~* Cardiac left ventricular function with resting ejection fraction of less than 50%.~* Any other concomitant serious illness or organ system dysfunction which in the opinion of the investigator would either compromise patient's safety or interfere with the evaluation of the safety of the test drug.~* Absolute neutrophil count (ANC) \< 1500 / mm³.~* Platelet count \< 75,000 / mm³~* Calculated creatinine clearance \< 60 ml / min (using Cockcroft-Gault formula for GFR estimate) or serum creatinine \> 1.5 times upper limit of normal.~* Uncontrolled hypercalcemia~* Patients unable to comply with the protocol.~* Known hepatitis B infection, known hepatitis C infection or known HIV carrier.~* Known or suspected active drug or alcohol abuse.~* Requirement for treatment with any of the prohibited concomitant medications~* Any contraindications for therapy with BIBW 2992.~* Known hypersensitivity to BIBW 2992.~* Use of any investigational drug within 4 weeks of start of treatment

- Gender: MALE
- Minimum Age: 18 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- BIBW 2992 (Afatinib) (Type: EXPERIMENTAL): BIBW 2992 (Afatinib) 50mg daily continuously (oral medication)

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: terminate
termination_type: enrollment issues