Please assess the completion status of the following clinical trial:

Trial Title: Mirdametinib + BGB-3245 in Advanced Solid Tumors

Study Design Characteristics:
- Allocation: NON_RANDOMIZED
- Intervention Model: SEQUENTIAL
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: NONE
- Phase: PHASE1/PHASE2
- Number of Arms: 4.0

Eligibility Criteria:
Key Inclusion Criteria:~* Able to provide informed consent~* At least 18 years of age on day of signing ICF~* Advanced, metastatic or unresectable solid cancer that has not responded to or progressed during or after at least 1 line of appropriate therapy or for which there is no treatment available or prior therapy was not tolerated.~* Part 1: oncogenic mutation or other genomic aberration of the MAPK pathway~* Part 2: oncogenic mutation or genomic aberration defined below:~  * Cohort A: cutaneous melanoma harboring NRAS mutations.~ * Cohort B: non-small cell lung cancer (NSCLC) harboring a KRAS mutation.~ * Cohort C: NSCLC or cutaneous melanoma harboring BRAF Class II or Class III mutations or BRAF Fusion mutation.~* Must have archival tumor tissue or agree to a fresh tumor biopsy at screening~* Measurable disease per RECIST 1.1~* Eastern Cooperative Oncology Group (ECOG) performance status of ≤ 2~* Adequate organ function and no transfusion within 14 days of first dose~Key Exclusion Criteria:~* Central Nervous System metastases, leptomeningeal carcinomatosis or untreated spinal cord compression~* History of glaucoma~* Active parathyroid disorder or history of malignancy associated hypercalcemia~* Clinically significant cardiac disease within the past 6 months of signing ICF~* History of toxicity from another RAF, MEK, ERK inhibitor requiring discontinuation of treatment from these agents~* Severe or uncontrolled systemic disease~* Inability to swallow oral medications~* Clinically significant active infection (HIV, Hepatitis B or Hepatitis C)~* History of or ongoing Immune Thrombocytopenia (ITP), Von Willebrand disease and/or other past or present bleeding disorders~* Underlying medical conditions in investigator's opinion to be unfavorable to be a part of the study~* Major surgical procedure or significant traumatic injury within 4 weeks prior to first dose or anticipates need for major surgery while on study~* Systemic anti-cancer therapy within 2 weeks or 5 half-lives before first dose~* Concomitant systemic or glucocorticoid therapy within 2 weeks before first dose~* Concomitant medicines that are strong CYP3A4 inhibitors or inducers within 2 weeks or 5 half-lives before first dose~* Live vaccine within 4 weeks before first dose

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- Phase 1 Dose Escalation Cohorts Ranging in Dose (Type: EXPERIMENTAL): Participants with an oncogenic mutation or other genomic aberration of the MAPK pathway
- Phase 2 Dose Expansion A (Type: EXPERIMENTAL): Participants with cutaneous melanoma harboring NRAS mutations
- Phase 2 Dose Expansion B (Type: EXPERIMENTAL): Participants with NSCLC harboring KRAS mutations
- Phase 2 Dose Expansion C (Type: EXPERIMENTAL): Participants with NSCLC or cutaneous melanoma harboring BRAF Class II or Class III mutation or BRAF Fusion mutation

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: terminate
termination_type: lack of efficacy