Please assess the completion status of the following clinical trial:

Trial Title: Treosulfan-based Conditioning in Paediatric Patients With Haematological Malignancies

Study Design Characteristics:
- Allocation: None
- Intervention Model: SINGLE_GROUP
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: NONE
- Phase: PHASE2
- Number of Arms: 1.0

Eligibility Criteria:
Inclusion Criteria:~1. Haematological malignant disease i.e. ALL, AML, MDS or JMML, indicated for allo-HSCT.~2. Indication for first allo-HSCT or second allo-HSCT due to disease relapse, graft failure, or secondary malignancy after previous HSCT.~3. Available matched sibling donor (MSD), matched family donor (MFD) or matched unrelated donor (MUD). For bone marrow (BM) and peripheral blood (PB) match is defined as 9/10 or 10/10 allele match after four digit typing in human leucocyte antigens (HLA)-A, B, C, DRB1 and DQB1.~4. Patients with ALL or AML in complete morphologic remission (blast counts \<5 % in BM) and patients with MDS or JMML with blast counts \< 20 % in BM at study entry.~5. Age at time of registration from 28 days to less than 18 years of age.~6. Lansky (patients aged \<16 years) or Karnofsky (patients aged ≥ 16 years) performance score of at least 70 %.~7. Written informed consent of the parents/ legal guardians and patient's assent/consent according to national regulations.~8. Females of child-bearing potential or male patients' partners with child-bearing potential must use a highly effective method of contraception (pearl index \< 1 %) such as complete sexual abstinence, combined oral contraceptive, hormone intrauterine contraceptive device (IUCD), vaginal hormone ring, transdermal contraceptive patch, contraceptive implant or depot contraceptive injection in combination with a second method of contraception like a condom or a cervical cap / diaphragm with spermicide or surgical sterilisation (vasectomy) in male patients or male partners during the study and at least 6 months thereafter.~9. Negative pregnancy test for females of child-bearing potential.~Exclusion Criteria:~1. Third or later allo-HSCT.~2. HSCT from haploidentical or umbilical cord blood donor.~3. Symptomatic involvement of central nervous system (CNS) at study entry.~4. Treatment with cytotoxic drugs within 10 days prior to day 7.~5. Obese paediatric patients with body mass index: weight (kg)/\[height (m)\]² \> 30 kg/m².~6. Solid tumours (e.g. neuroblastoma, peripheral neuroectodermal tumour \[PNET\], Ewing sarcoma).~7. Fanconi anaemia and other deoxyribonucleic acid (DNA) breakage repair disorders.~8. Impaired liver function indicated by Bilirubin \> three times the upper limit of normal (ULN) or aspartate aminotransferase/alanine aminotransferase (AST/ALT) \> five times ULN, or active infectious hepatitis.~9. Impaired renal function indicated by estimated glomerular filtration rate (\[GFR\], according to the Schwartz formula) \< 60 mL/min/1,73m2.~10. Impaired cardiac function: severe cardiac insufficiency indicated by left ventricle ejection fraction (LVEF) \< 35 %.~11. Requirement for supplementary continuous oxygen.~12. Severe active infection requiring deferral of conditioning.~13. Human immunodeficiency virus (HIV) positivity.~14. Known pregnancy, breast feeding.~15. Known hypersensitivity to Treosulfan and/or Fludarabine.

- Gender: ALL
- Minimum Age: 28 Days
- Maximum Age: 17 Years
- Healthy Volunteers: f

Study Arms:
- Treosulfan (Type: EXPERIMENTAL): Treosulfan dose per day is to be calculated by using BSA. One dose of Treosulfan per day on three consecutive days (day -6, day -5 and day -4) as intravenous (i.v.) infusion, given over 2 hours.~Two background conditioning regimens with Treosulfan are allowed: One regimen consists of a standardised Fludarabine-containing regimen (regimen A) and the other consists of an intensified regimen with Fludarabine and ThioTEPA (regimen B). The investigator decides for each individual patient whether to treat the patient with regimen A or with regimen B.~Treosulfan: i.v., BSA adapted: 10, 12 or 14 g/m²/day within 120 min to be administered prior to Fludarabine; Fludarabine: i.v., 30 mg/m2/day on days from -7 to -3 prior to HSCT; ThioTEPA (Regimen B): i.v., 2 x 5mg/kg/day on day -2.

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: complete