Please assess the completion status of the following clinical trial:

Trial Title: HP Xenon-129 fMRI of Healthy Volunteers and Participants With Alzheimer's Disease

Study Design Characteristics:
- Allocation: RANDOMIZED
- Intervention Model: PARALLEL
- Observational Model: None
- Primary Purpose: BASIC_SCIENCE
- Time Perspective: None
- Masking: NONE
- Phase: EARLY_PHASE1
- Number of Arms: 2.0

Eligibility Criteria:
Inclusion Criteria:~A participant is eligible for inclusion in the study if the individual meets all of the following criteria:~1. Self-reported proficiency in English language.~2. Equal to or more than 8 years of education.~3. Normal or corrected to normal vision.~4. Able to provide informed consent.~5. Able to hold their breath for 20 seconds.~Normal cognition for healthy participant group inclusion criteria:~1. Preserved independence in functional abilities.~2. MoCA score no less than 26.~3. Males and non-lactating females of 18 to 85 years of age.~Alzheimer's disease group inclusion criteria:~1. Participants meet National Institute on Aging-Alzheimer's Association for probable or possible Alzheimer's Disease dementia.~2. MoCA score no less than 16.~3. Males and non-lactating females of 60 to 85 years of age.~4. Have a family member, close friend, or LAR that can be present for the informed consent process and study visits.~Exclusion Criteria:~A participant is ineligible for the study if the individual meets any of the following criteria:~1. Serious underlying medical condition, other, then the condition being investigated, which may affect cognitive function of the participant (in the opinion of the investigator): substance abuse, psychotic or depressive disorder, advanced or poorly controlled cardiac, pulmonary, hepatic, renal, neurological disorders in which the patient has significant speech, visual, motor or cognitive deficit, seizure disorders, endocrine or infectious disease or active malignancy.~2. MRI incompatibility as determined by MR Technologist during MRI screening.~3. Self-identifies as claustrophobic.~4. Female exclusion only: Are or may be pregnant; Planning on becoming pregnant.~5. Is a student currently enrolled in a course at Lakehead University where the Principal Investigator (PI) is the instructor.~6. Is a student currently enrolled in a degree program at Lakehead University where the PI is their direct thesis supervisor.~7. Is currently an employee of the PI at the Thunder Bay Regional Research Institute (TBRRI) and/or Lakehead University.~Normal cognition group exclusion criteria:~1. History of diagnosed neurological disease or injury.~Alzheimer's disease group exclusion criteria:~1. Existing diagnosis of dementia of etiology other than Alzheimer's disease.~2. Acute Delirium on the day of scanning (CAM tool assessment)

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: 85 Years
- Healthy Volunteers: t

Study Arms:
- Healthy Volunteers (Type: OTHER): Healthy volunteers will inhale NeuroXene using various breathing methods. The CMRS 1H-129Xe dual-tuned quadrature head coil will be used to acquire MRI images of the human brain after inhalation of NeuroXene. The coil permits the acquisition of both conventional proton and HP xenon gas images. Two types of MRI scans will be performed: Traditional proton fMRI and Hyperpolarized Xenon-129 fMRI. The order of scans will be randomized to account for bias caused by scan order.
- Alzheimer's Disease Participants (Type: OTHER): Alzheimer's disease participants will inhale NeuroXene using various breathing methods. The CMRS 1H-129Xe dual-tuned quadrature head coil will be used to acquire MRI images of the human brain after inhalation of NeuroXene. The coil permits the acquisition of both conventional proton and HP xenon gas images. Two types of MRI scans will be performed: Traditional proton fMRI and Hyperpolarized Xenon-129 fMRI. The order of scans will be randomized to account for bias caused by scan order.

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: terminate
termination_type: enrollment issues