Please assess the completion status of the following clinical trial:

Trial Title: A Trial of PEGPH20 in Combination With Avelumab in Chemotherapy Resistant Pancreatic Cancer

Study Design Characteristics:
- Allocation: None
- Intervention Model: SINGLE_GROUP
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: NONE
- Phase: EARLY_PHASE1
- Number of Arms: 1.0

Eligibility Criteria:
Key Inclusion Criteria:~* Signed, written IRB/IEC-approved Informed Consent Form~* Histologically or cytologically-confirmed pancreatic ductal adenocarcinoma (PDAC).~* Accessible tumor for two repeated tumor biopsies.~* Progression to first line treatment for locally advanced or advanced disease. Prior adjuvant chemotherapy or chemoradiation therapy for early disease is allowed.~* Age ≥18 years.~* Radiologically measurable disease per RECIST v1.1.~* Performance-status ECOG 0 -2.~* Life expectancy ≥ 3 months.~* Resolved acute effects of any prior therapy to baseline or Grade ≤1 severity~* Screening laboratory:~  1. Hematologic: ANC ≥ 1.5 × 109/L, platelet count ≥ 100 × 109/L, and hemoglobin ≥ 9 g/dL~ 2. Hepatic: Total bilirubin level ≤ 1.5 × the ULN range and AST and ALT levels ≤ 2.5 × ULN or AST and ALT levels ≤ 5 X ULN (for subjects with documented metastatic disease to the liver)~ 3. Renal: Estimated creatinine clearance ≥ 30 mL/min according to the Cockcroft-Gault formula or serum creatinine ≤ 2.0 mg/dL.~ 4. Albumin ≥2.5 g/dL.~ 5. Coagulation: PT time and INR within normal limits (+/-15%). PTT within normal limits (+/-15%).~* If a subject requires anticoagulation, treatment must be modified to enoxaparin.~* Negative serum pregnancy test if female subject is of childbearing potential.~* Patients who are willing and able to comply with scheduled visits, treatment plans, laboratory tests, biopsies when required, and other procedures.~Exclusion Criteria:~* Clinical evidence of DVT, PE, prior history of CVA or history of TIA within 12 months or other known TE event present during the screening period~* Current use of megestrol acetate (use within 10 days of Day 1).~* Contraindication to heparin as per institutional guidelines.~* Another primary cancer within the last 3 years currently requiring antineoplastic treatment within the exception of non-melanoma skin cancer, early-stage prostate cancer, or curatively treated cervical carcinoma in-situ.~* Current use of immunosuppressive medication within 2 weeks of study participation, EXCEPT for those listed in protocol~* Active autoimmune disease that might deteriorate when receiving an immuno-stimulatory agent: Patients with diabetes type I, vitiligo, psoriasis, or hypo- or hyperthyroid diseases not requiring immunosuppressive treatment are eligible.~* Prior organ transplantation including allogenic stem-cell transplantation.~* Active infection requiring systemic therapy.~* Known infection with human immunodeficiency virus, Hepatitis B, or Hepatitis C~* Known prior severe hypersensitivity to investigational product, hyaluronidase, or any component in its formulations, including known severe hypersensitivity reactions to monoclonal antibodies (NCI CTCAE v4.03 Grade ≥ 3).~* Any history of anaphylaxis or uncontrolled asthma (that is, 3 or more features of partially controlled asthma).~* Clinically significant (i.e., active) cardiovascular disease: myocardial infarction (\< 6 months prior to enrollment), unstable angina, congestive heart failure (≥ New York Heart Association Classification Class II), or serious cardiac arrhythmia requiring medication.~* Prior cerebrovascular accident/stroke.~* Clinically significant carotid artery disease (e.g. prior carotid surgery, symptomatic and/or requires treatment)~* Inability to comply with study and follow-up procedures as judged by the Investigator.~* Known alcohol or drug abuse.

- Gender: ALL
- Minimum Age: 18 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- PEGPH20 + Avelumab (Type: EXPERIMENTAL): PEGPH20, a multi-site PEGylated enzyme generated by conjugating N-hydroxysuccinimidyl ester of methoxypoly(ethylene glycol)-butanoic acid (MSBA30K/B or PEG) and recombinant human hyaluronidase (rHuPH20). PEGPH20 has a half-life of approximately 2 days, thereby enabling systemic activity and sustained duration of action to degrade HA. In many different tumor types tested in murine xenograft models, response to PEGPH20 has been shown to be more robust for tumors characterized by higher HA expression.

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: terminate
termination_type: enrollment issues