Please assess the completion status of the following clinical trial:

Trial Title: Safety and Oversight of the Individually Tailored Treatment Approach: A Novel Pilot Study

Study Design Characteristics:
- Allocation: None
- Intervention Model: SINGLE_GROUP
- Observational Model: None
- Primary Purpose: TREATMENT
- Time Perspective: None
- Masking: NONE
- Phase: None
- Number of Arms: 1.0

Eligibility Criteria:
Inclusion Criteria:~1. Patient or their parent(s)/legal guardian(s) has provided written informed consent using the main study PICF~2. Continues to meet all the inclusion criteria as per the TRIAGE Framework protocol as follows:~   1. Male or female patient, aged 2 years or older~  2. Patient has pathologically confirmed locally advanced, incurable or metastatic cancer of any histological type~  3. Have an available TRIAGE sub-study with a matched therapy~  4. Documented progression following standard therapy, or for whom, in the opinion of the Investigator, no appropriate standard therapy exists~  5. Life expectancy of \> 3 months~  6. Adequate performance status:~   i. For patients aged 18 years or over, Eastern Cooperative Oncology Group (ECOG) performance status ≤ 2 (appendix 1) ii. For patients aged 17 years, Karnofsky score ≥ 50 (appendix 2) iii. For patients aged 16 years or under, Lansky score ≥ 50 (appendix 3)~3. Treatment regimen and schedule of assessments that has been approved by the TAILOR Study Committee~4. Approved treatment is obtainable~5. Patient has measurable disease or evaluable disease as defined by RECIST 1.1 (or RANO criteria for primary CNS cancers or the Cheson (IWG) revised response criteria for lymphomas)~6. Patient must have adequate bone marrow, hepatic and renal function within 7 days prior to registration:~   * ANC ≥ 1.5 x 109/L~  * Platelet count ≥ 100 x 109/L (platelet count ≥ 50 x 109/L for haematological malignancy indications)~  * ALT ≤ 2.5x ULN, unless liver metastases or invasion are present, in which case it must be ≤ 5x ULN~  * AST ≤ 2.5x ULN, unless liver metastases or invasion are present, in which case it must be ≤ 5x ULN~  * Total bilirubin ≤ 1.5x ULN except patients with Gilbert's Syndrome, who are eligible in consultation with their physician~  * Serum creatinine ≤ 1.5x ULN~7. Patient is willing and able to comply with the protocol for the duration of the study including undergoing, treatment, and scheduled visits and examination including follow up~8. Female patients of childbearing potential must have a negative serum pregnancy test at screening for the main study and agree to use highly effective methods of birth control while receiving approved treatment through to the time frame specified in the approved ITAP after the last dose. Patients of childbearing potential are those who have not been surgically sterilised or have not been free from menses for \> 1 year.~9. Sexually active males must agree to use a condom during intercourse while taking the approved treatment through to the time frame specified in the approved ITAP after the last dose and should not father a child in this period.~Exclusion Criteria:~1. One or more of the exclusion criteria as per the TRIAGE Framework protocol applies as follows:~   1. Significant cardiovascular disease~  2. Any other disease, metabolic dysfunction, physical examination finding, or clinical laboratory finding that contraindicates the use of an investigational drug, may affect the interpretation of the results, or may render the patient at high risk from treatment complications~  3. Other co-morbidities or conditions that may compromise assessment of key outcomes or in the opinion of the clinician, limit the ability of the patient to comply with the protocol~2. Any unresolved toxicity (≥CTCAE grade 2) from previous anti-cancer therapy, with the exception of alopecia.~   Patients with irreversible toxicity that is not reasonably expected to be exacerbated by the investigational product(s) may be included (e.g. hearing loss, peripheral neuropathy)~3. Symptomatic, or actively progressing CNS metastases (unless a primary brain tumour).Patients with a history of treated~   CNS lesions are eligible, provided that all of the following criteria are met:~   Measurable disease per RECIST 1.1 must be present outside the CNS Metastases are limited to the cerebellum or the supratentorial region (i.e. no metastases to the midbrain, pons, medulla, or spinal cord) There is no clinical evidence of interim progression between completion of CNS-directed therapy and registration on the study (radiological re-assessment is not required) The patient has not received radiotherapy within 14 days prior to registration Anticonvulsant therapy at a stable dose is permitted~4. History of leptomeningeal disease unless a primary brain tumour~5. Known active infection including tuberculosis, HBV, HCV, or HIV. Patients with a past or resolved HBV infection (defined as the presence of HBcAb and absence of HBsAg) are eligible. Patients with a past or resolved HCV infection are eligible only if polymerase chain reaction is negative for HCV RNA~Additional inclusion and/or exclusion criteria for the main study will be stipulated in the approved Individualised Treatment and Assessment Plan as each treatment regimen is expected to have specific requirements.

- Gender: ALL
- Minimum Age: 2 Years
- Maximum Age: None
- Healthy Volunteers: f

Study Arms:
- Treatment (Type: EXPERIMENTAL): All participants will have an individualised treatment plan. The possible treatments that can be prescribed are as follows, they may be given as a single agent or in combination~* Trametinib 2 mg/day~* Cobimetinib 60 mg/day, on day 1-21 of each 28 day cycle (21 days on, 7 days off)~* Binimetinib 45 mg/ twice a day~* Alpelisib 300 mg/day~* Vemurafenib 960 mg twice a day~* Dabrafenib 150 mg twice a day~* Encorafenib 450 mg/day~* Palbociclib 125 mg/day, on day 1-21 of each 28 day cycle (21 days on, 7 days off)~* Ribociclib 600 mg/day, on day 1-21 of each 28 day cycle (21 days on, 7 days off~* Abemaciclib 150 mg twice a day~* Olaparib 300 mg twice a day~* Talazoparib 1 mg/day~* Nivolumab 240 mg IV once every two weeks~* Atezolizumab 1200 mg IV on day 1 of a 21 day cycle~* Pembrolizumab 200 mg IV on day 1 of a 21 day cycle

Based on this trial design, predict the completion outcome and termination type (if applicable).

Answer: outcome: terminate
termination_type: enrollment issues