TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Lactobacillus GG in the Prophylaxis of Ventilator Associated Pneumonia: A Prospective, Randomized, Placebo-controlled, Double-blind Study
Brief Summary: This study utilizes lactobacillus, or probiotics, delivered twice daily to the mouth and stomach, via feeding tube, in effort to determine whether the oral administration of a naturally occurring Lactobacillus species reduces the incidence of ventilator associated pneumonia therefore reducing intensive care unit(ICU)complications.


Options:
A: Arm Label: BB-12; Type: EXPERIMENTAL; Interventions: Biological: Bifidobacterium animalis subsp. lactis BB-12 | Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Other: Control | Intervention Type: BIOLOGICAL; Name: Bifidobacterium animalis subsp. lactis BB-12; Assigned to Arm(s): BB-12 | Intervention Type: OTHER; Name: Control; Assigned to Arm(s): Control
B: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Lactobacillus GG | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: placebo | Intervention Type: DIETARY_SUPPLEMENT; Name: Lactobacillus GG; Assigned to Arm(s): 1 | Intervention Type: DIETARY_SUPPLEMENT; Name: placebo; Assigned to Arm(s): 2
C: Arm Label: Probiotics; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Probiotic capsules | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Placebo capsules | Intervention Type: DIETARY_SUPPLEMENT; Name: Probiotic capsules; Assigned to Arm(s): Probiotics | Intervention Type: DIETARY_SUPPLEMENT; Name: Placebo capsules; Assigned to Arm(s): Placebo
D: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Arm Label: Kefir; Type: EXPERIMENTAL; Interventions: Other: Kefir | Intervention Type: OTHER; Name: Kefir; Assigned to Arm(s): Kefir | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Placebo

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Comparison of Pain Experienced by Patients Undergoing Endometrial Biopsy by Pipelle and Explora Curette
Brief Summary: The purpose of this study is to determine the level of pain women experience during an endometrial biopsy and the effect that the biopsy tool might have on that pain. The investigators will also evaluate the adequacy of the sample each endometrial biopsy tool collects.


Options:
A: Arm Label: Endometrial injury group; Type: EXPERIMENTAL; Interventions: Procedure: Endometrial injury | Arm Label: Control group; Type: SHAM_COMPARATOR; Interventions: Procedure: Control group | Intervention Type: PROCEDURE; Name: Endometrial injury; Assigned to Arm(s): Endometrial injury group | Intervention Type: PROCEDURE; Name: Control group; Assigned to Arm(s): Control group
B: Arm Label: Pipelle Group; Type: ACTIVE_COMPARATOR; Interventions: Device: Pipelle de Cornier | Arm Label: Explora group; Type: ACTIVE_COMPARATOR; Interventions: Device: Explora curette | Intervention Type: DEVICE; Name: Pipelle de Cornier; Assigned to Arm(s): Pipelle Group | Intervention Type: DEVICE; Name: Explora curette; Assigned to Arm(s): Explora group
C: Arm Label: Scrathcing; Type: EXPERIMENTAL; Interventions: Procedure: scratching | Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Procedure: scratching | Intervention Type: PROCEDURE; Name: scratching; Assigned to Arm(s): Control, Scrathcing
D: Arm Label: Office hysteroscopy and endometrial snip; Type: EXPERIMENTAL; Interventions: Procedure: Office hysteroscopy and endometrial snip | Arm Label: Office hyteroscopy; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Office hysteroscopy | Intervention Type: PROCEDURE; Name: Office hysteroscopy and endometrial snip; Assigned to Arm(s): Office hysteroscopy and endometrial snip | Intervention Type: PROCEDURE; Name: Office hysteroscopy; Assigned to Arm(s): Office hyteroscopy

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Comparison of Pain Experienced by Patients Undergoing Endometrial Biopsy by Pipelle and Explora Curette
Brief Summary: The purpose of this study is to determine the level of pain women experience during an endometrial biopsy and the effect that the biopsy tool might have on that pain. The investigators will also evaluate the adequacy of the sample each endometrial biopsy tool collects.


Options:
A: Arm Label: clomiphene and endometrial sampling; Type: ACTIVE_COMPARATOR; Interventions: Device: endometrial sampling, Drug: clomiphene citrate | Arm Label: clomiphene citrate; Type: ACTIVE_COMPARATOR; Interventions: Drug: clomiphene citrate | Intervention Type: DEVICE; Name: endometrial sampling; Assigned to Arm(s): clomiphene and endometrial sampling | Intervention Type: DRUG; Name: clomiphene citrate; Assigned to Arm(s): clomiphene and endometrial sampling, clomiphene citrate
B: Arm Label: Scrathcing; Type: EXPERIMENTAL; Interventions: Procedure: scratching | Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Procedure: scratching | Intervention Type: PROCEDURE; Name: scratching; Assigned to Arm(s): Control, Scrathcing
C: Arm Label: Pipelle Group; Type: ACTIVE_COMPARATOR; Interventions: Device: Pipelle de Cornier | Arm Label: Explora group; Type: ACTIVE_COMPARATOR; Interventions: Device: Explora curette | Intervention Type: DEVICE; Name: Pipelle de Cornier; Assigned to Arm(s): Pipelle Group | Intervention Type: DEVICE; Name: Explora curette; Assigned to Arm(s): Explora group
D: Arm Label: Office hysteroscopy and endometrial snip; Type: EXPERIMENTAL; Interventions: Procedure: Office hysteroscopy and endometrial snip | Arm Label: Office hyteroscopy; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Office hysteroscopy | Intervention Type: PROCEDURE; Name: Office hysteroscopy and endometrial snip; Assigned to Arm(s): Office hysteroscopy and endometrial snip | Intervention Type: PROCEDURE; Name: Office hysteroscopy; Assigned to Arm(s): Office hyteroscopy

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Efficacy of a Training Intervention on the Quality of Case Coordinators and Nurses' Decision Support for Patients Deciding About the Place of Care at the End Of-Life: A Randomized Control Trial
Brief Summary: Most dying cancer patients would prefer a home death yet die in an institution. Patients can experience uncertainty when weighing practical considerations, concern for others, and their personal ratings about the desirability and undesirability of various outcomes related to different locations of care. Health professionals, trained in decision support, can help patients to make decisions that are informed by both relevant information and what outcomes are most valued by patients. Therefore, I will study if an educational intervention can help nurses and case managers to strengthen their skills and confidence in providing patient decision support around place of end of life care.

Project Description:

Using a two step approach I will study if the quality of providers decision support can be improved with an education. In step one nurses and care coordinators will be interviewed to identify factors that make it easier or more difficult to provide patient decision support. This information will be used to develop an education program. In step two, nurses and care coordinator volunteers will be assigned by a flip of a coin to either receive the decision support education or not. Before and after the education program the quality of the decision support participants provide will be measured and compared. As well, participants receiving the education program will be asked about their satisfaction with the education program.


Options:
A: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Decision support skills building Intervention | Intervention Type: BEHAVIORAL; Name: Decision support skills building Intervention; Assigned to Arm(s): 1
B: Intervention Type: PROCEDURE; Name: family conference with bereavement information leaflet; Assigned to Arm(s): N/A
C: Arm Label: communication lecture; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: communication lecture | Arm Label: lecture plus CD-ROM; Type: EXPERIMENTAL; Interventions: Behavioral: lecture plus CD-ROM | Intervention Type: BEHAVIORAL; Name: communication lecture; Assigned to Arm(s): communication lecture | Intervention Type: BEHAVIORAL; Name: lecture plus CD-ROM; Assigned to Arm(s): lecture plus CD-ROM
D: Arm Label: Intervention Group; Type: EXPERIMENTAL; Interventions: Other: Loop | Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Loop; Assigned to Arm(s): Intervention Group

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase III Randomized Clinical Trial of Laparoscopic or Robotic Radical Hysterectomy Versus Abdominal Radical Hysterectomy in Patients With Early Stage Cervical Cancer
Brief Summary: The goal of this clinical research study is to compare the long-term outcomes of different surgical methods for the treatment of cervical cancer. The long-term outcome of a total abdominal radical hysterectomy (TARH) will be compared against laparoscopy. In this study, the laparoscopy will be done with or without robotic technology.


Options:
A: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Total Abdominal Radical Hysterectomy | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Procedure: Total Laparoscopic or Robotic Radical Hysterectomy | Intervention Type: PROCEDURE; Name: Total Abdominal Radical Hysterectomy; Assigned to Arm(s): 1 | Intervention Type: PROCEDURE; Name: Total Laparoscopic or Robotic Radical Hysterectomy; Assigned to Arm(s): 2
B: Arm Label: Transperitoneal; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Transperitoneal laparoscopic aortic lymphadenectomy | Arm Label: Extraperitoneal; Type: EXPERIMENTAL; Interventions: Procedure: Extraperitoneal laparoscopic aortic lymphadenectomy | Intervention Type: PROCEDURE; Name: Transperitoneal laparoscopic aortic lymphadenectomy; Assigned to Arm(s): Transperitoneal | Intervention Type: PROCEDURE; Name: Extraperitoneal laparoscopic aortic lymphadenectomy; Assigned to Arm(s): Extraperitoneal
C: Arm Label: Robotic surgery; Type: EXPERIMENTAL; Interventions: Procedure: Robotic surgery | Arm Label: Abdominal surgery; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Abdominal surgery | Intervention Type: PROCEDURE; Name: Robotic surgery; Assigned to Arm(s): Robotic surgery | Intervention Type: PROCEDURE; Name: Abdominal surgery; Assigned to Arm(s): Abdominal surgery
D: Arm Label: Robotic-assisted prolapse repair; Type: N/A; Interventions: N/A | Arm Label: Vaginal prolapse repair; Type: N/A; Interventions: N/A

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase III Randomized Clinical Trial of Laparoscopic or Robotic Radical Hysterectomy Versus Abdominal Radical Hysterectomy in Patients With Early Stage Cervical Cancer
Brief Summary: The goal of this clinical research study is to compare the long-term outcomes of different surgical methods for the treatment of cervical cancer. The long-term outcome of a total abdominal radical hysterectomy (TARH) will be compared against laparoscopy. In this study, the laparoscopy will be done with or without robotic technology.


Options:
A: Arm Label: IC Green Arm; Type: EXPERIMENTAL; Interventions: Drug: IC Green | Intervention Type: DRUG; Name: IC Green; Assigned to Arm(s): IC Green Arm
B: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Total Abdominal Radical Hysterectomy | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Procedure: Total Laparoscopic or Robotic Radical Hysterectomy | Intervention Type: PROCEDURE; Name: Total Abdominal Radical Hysterectomy; Assigned to Arm(s): 1 | Intervention Type: PROCEDURE; Name: Total Laparoscopic or Robotic Radical Hysterectomy; Assigned to Arm(s): 2
C: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Procedure: Detection of sentinel node | Intervention Type: PROCEDURE; Name: Detection of sentinel node; Assigned to Arm(s): 1
D: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Procedure: No Lymphadenectomy (LNE) | Arm Label: B; Type: EXPERIMENTAL; Interventions: Procedure: Lymphadenectomy (LNE) | Intervention Type: PROCEDURE; Name: No Lymphadenectomy (LNE); Assigned to Arm(s): A | Intervention Type: PROCEDURE; Name: Lymphadenectomy (LNE); Assigned to Arm(s): B

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase III Randomized Clinical Trial of Laparoscopic or Robotic Radical Hysterectomy Versus Abdominal Radical Hysterectomy in Patients With Early Stage Cervical Cancer
Brief Summary: The goal of this clinical research study is to compare the long-term outcomes of different surgical methods for the treatment of cervical cancer. The long-term outcome of a total abdominal radical hysterectomy (TARH) will be compared against laparoscopy. In this study, the laparoscopy will be done with or without robotic technology.


Options:
A: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Conventional Laparoscopic Hysterectomy | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Robot-assisted (Da Vinci®) laparoscopic hysterectomy | Intervention Type: PROCEDURE; Name: Conventional Laparoscopic Hysterectomy; Assigned to Arm(s): 1 | Intervention Type: PROCEDURE; Name: Robot-assisted (Da Vinci®) laparoscopic hysterectomy; Assigned to Arm(s): 2
B: Arm Label: Robotic Surgery; Type: EXPERIMENTAL; Interventions: Procedure: Robotic surgery | Arm Label: Laparoscopy; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Laparoscopic Surgery | Intervention Type: PROCEDURE; Name: Robotic surgery; Assigned to Arm(s): Robotic Surgery | Intervention Type: PROCEDURE; Name: Laparoscopic Surgery; Assigned to Arm(s): Laparoscopy
C: Arm Label: Laparoscopic Abdominal Sacrocolpopexy (LASC); Type: ACTIVE_COMPARATOR; Interventions: Procedure: Standard laparoscopic abdominal sacrocolpopexy | Arm Label: Robotic Assisted Laparoscopic (RASC); Type: EXPERIMENTAL; Interventions: Procedure: Robotic assisted laparoscopic abdominal sacrocolpopexy | Intervention Type: PROCEDURE; Name: Robotic assisted laparoscopic abdominal sacrocolpopexy; Assigned to Arm(s): Robotic Assisted Laparoscopic (RASC) | Intervention Type: PROCEDURE; Name: Standard laparoscopic abdominal sacrocolpopexy; Assigned to Arm(s): Laparoscopic Abdominal Sacrocolpopexy (LASC)
D: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Total Abdominal Radical Hysterectomy | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Procedure: Total Laparoscopic or Robotic Radical Hysterectomy | Intervention Type: PROCEDURE; Name: Total Abdominal Radical Hysterectomy; Assigned to Arm(s): 1 | Intervention Type: PROCEDURE; Name: Total Laparoscopic or Robotic Radical Hysterectomy; Assigned to Arm(s): 2

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: An Open Label Follow-up Trial of the Efficacy and Safety of Chronic Administration of the Combination of Telmisartan 40mg + Amlodipine 5mg or the Combination of Telmisartan 80mg + Amlodipine 5mg Tablets Alone or in Combination With Other Antihypertensive Medications in Patients With Hypertension.
Brief Summary: The primary objective of this trial is to assess the efficacy and safety of the fixed dose combinations telmisartan 40 mg / amlodipine 5 mg (T40/A5) or telmisartan 80 mg / amlodipine 5 mg (T80/A5) during long-term open-label treatment.


Options:
A: Intervention Type: DRUG; Name: Amlodipine/Atorvastatin; Assigned to Arm(s): N/A
B: Intervention Type: DRUG; Name: telmisartan/amlodipine 40/5 mg fixed combination; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: telmisartan/amlodipine 80/5 mg fixed combination; Assigned to Arm(s): N/A
C: Arm Label: polypill; Type: EXPERIMENTAL; Interventions: Drug: polypill | Arm Label: Usual Care; Type: ACTIVE_COMPARATOR; Interventions: Drug: Usual cardiovascular medications | Intervention Type: DRUG; Name: polypill; Assigned to Arm(s): polypill | Intervention Type: DRUG; Name: Usual cardiovascular medications; Assigned to Arm(s): Usual Care
D: Arm Label: Azilsartan Medoxomil 40 mg/Chlorthalidone 12.5 mg QD; Type: EXPERIMENTAL; Interventions: Drug: Azilsartan medoxomil and chlorthalidone | Arm Label: Azilsartan Medoxomil 40 mg + Hydrochlorothiazide 12.5 mg QD; Type: EXPERIMENTAL; Interventions: Drug: Azilsartan medoxomil and hydrochlorothiazide | Intervention Type: DRUG; Name: Azilsartan medoxomil and chlorthalidone; Assigned to Arm(s): Azilsartan Medoxomil 40 mg/Chlorthalidone 12.5 mg QD | Intervention Type: DRUG; Name: Azilsartan medoxomil and hydrochlorothiazide; Assigned to Arm(s): Azilsartan Medoxomil 40 mg + Hydrochlorothiazide 12.5 mg QD

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Multicenter, Prospective, Randomized Controlled Trial for the Detection of Colon Polyps and Predicting Histology
Brief Summary: In this study the investigators hypothesize that High Definition White Light colonoscopy and narrow band imaging (NBI) will detect a higher number of adenomas compared to standard definition white light colonoscopy. NBI will have a higher accuracy in predicting polyp histology compared to high definition colonoscopy and standard colonoscopy.

Specific Aim 1 - To compare the prevalence of adenomas detected by standard colonoscopy, high-definition white light colonoscopy and NBI.

Specific Aim 2 - To compare the number of adenoma detected per subject by standard colonoscopy, high-definition white light colonoscopy and NBI.

Specific Aim 3 - To compare the accuracy of predicting polyp histology between standard colonoscopy, high-definition white light colonoscopy and NBI by evaluating the surface mucosal and vascular patterns during the procedure.

Specific Aim 4 - To determine the inter-observer agreement between investigators for the recognition of various polyp patterns


Options:
A: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Procedure: standard of care colonoscopy | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Procedure: standard of care colonoscopy | Arm Label: 3; Type: EXPERIMENTAL; Interventions: Procedure: colonoscopy | Intervention Type: PROCEDURE; Name: standard of care colonoscopy; Assigned to Arm(s): 1 | Intervention Type: PROCEDURE; Name: colonoscopy; Assigned to Arm(s): 3 | Intervention Type: PROCEDURE; Name: standard of care colonoscopy; Assigned to Arm(s): 2
B: Intervention Type: DRUG; Name: Esomeprazole; Assigned to Arm(s): N/A
C: Arm Label: Narrow band imaging colonoscope; Type: EXPERIMENTAL; Interventions: Device: Narrow band imaging colonoscope | Arm Label: White Light; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: Narrow band imaging colonoscope; Assigned to Arm(s): Narrow band imaging colonoscope
D: Arm Label: colonoscopy; Type: EXPERIMENTAL; Interventions: Device: Olympus NBI colonoscope 180 HDTV narrow band imaging (diagnostic test) | Intervention Type: DEVICE; Name: Olympus NBI colonoscope 180 HDTV narrow band imaging (diagnostic test); Assigned to Arm(s): colonoscopy

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Study Evaluating the Effects of a Structured Lifestyle Intervention on Daily Physical Activity Level of COPD Patients in the First, Second and Third Echelon.
Brief Summary: Chronic Obstructive Pulmonary Disease (COPD) is increasing in the Netherlands. COPD is characterized by a deterioration of lung function, a lowering physical activity level and a low state of quality of life.

The aim of this randomized controlled study is to investigate the effects of a structured lifestyle program compared with usual care (in the first, second and third echelon) on the physical activity level of COPD patients.

150 COPD patients (GOLD I-IV) will be included, aged between 40 and 80 years. In each echelon 25 patients will participate in a structured lifestyle program and 25 patients will be treated with usual care.

In the structured lifestyle program, patients will be stimulated individually to enhance a physically active lifestyle. The primary outcome parameter is daily physical activity (steps/ day) assessed with a pedometer.

According to the study protocol patients in the experimental group and the control group participate in four measurement sessions distributed over 15 months. In each assessment a physical fitness test, lung function and questionnaires are taken. Patients of the experimental group participate in five individual counseling sessions and one telephonic counseling.


Options:
A: Arm Label: KOLwebben; Type: EXPERIMENTAL; Interventions: Behavioral: KOLwebben | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: KOLwebben; Assigned to Arm(s): KOLwebben
B: Arm Label: Usual Care; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Usual care | Arm Label: Counseling; Type: EXPERIMENTAL; Interventions: Behavioral: physical activity counseling | Intervention Type: BEHAVIORAL; Name: physical activity counseling; Assigned to Arm(s): Counseling | Intervention Type: BEHAVIORAL; Name: Usual care; Assigned to Arm(s): Usual Care
C: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: N-acetylcysteine; Type: ACTIVE_COMPARATOR; Interventions: Drug: N-acetycysteine (600mg twice daily) | Intervention Type: DRUG; Name: N-acetycysteine (600mg twice daily); Assigned to Arm(s): N-acetylcysteine | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Coach, using a stepcounter with exercise counseling | Arm Label: 2; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Coach, using a stepcounter with exercise counseling; Assigned to Arm(s): 1

Answer: D