TrialPanorama/Dataset huggingface dataset:
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Impact Evaluation of a Parenting Program to Improve Parenting, Education, and Health Outcomes for Young Children in Liberia
Brief Summary: The aim of this study is to assess the impact of an intervention to improve parenting practices, pre-academic and developmental skills, and use of mosquito nets for children in kindergarten in Liberia. A rigorous impact evaluation using a randomized, waitlist controlled design will be conducted to measure the impact of the intervention on three primary outcomes: positive parenting skills, children's cognitive and educational skills, and malaria knowledge and prevention behaviors.


Options:
A: Inclusion Criteria:

* Caregiver must live with child at least 4 nights per week
* Child must be between 2 and 9 years old Live in Khayelitsha or Nyanga
* May include biological parents, relatives or non-kin foster caregivers, with no restrictions on biological relationship
* Participant must self-identify as the primary caretaker of the child
* Children scoring 15 or higher in the Eyberg Child Behaviour Inventory problem scale

Exclusion Criteria:

* Children scoring 14 or lower in the Eyber Child Behaviour Inventory problem scale
* Participants with child not between 2 and 9 years old
* Participants not self-identifying as the primary care take of the child
* Participants not living with the child at least 4 nights per week.
B: Inclusion Criteria:

* patients with a known diagnosis of Diabetes Mellitus Type 2 given by their attending physicians,
* aged between 18 to 65 years old
* currently attending the health clinics in Putrajaya.
* able to provide consent independently without assistance.

Exclusion Criteria:

* patients that are not able to write and read,
* does not understand Malay or English,
* has a serious acute medical illness (e.g. delusional, delirium) during the intake.
* Patients who are currently attending intensive psychological treatment
C: Inclusion Criteria:

* Parents or primary caregivers (age 18 or above) of children ages 3-7 enrolled in kindergarten
* Resident in one of five study sites

Exclusion Criteria:

* Severe cognitive disability of caregiver affecting ability to provide informed consent
D: Inclusion Criteria:

* Age above 18;
* Suffering from a Common Mental Disorder (as defined by an a priori cut-off score on the 12 item General Health Questionnaire)
* Resident in the state (Goa) for the subsequent 12 months
* Not requiring urgent medical/surgical attention (e.g hospital admission)

Exclusion Criteria:

* Suffering from a cognitive or sensory impairment which makes participation in the evaluation difficult
* Not speaking Konkani, Marathi, Hindi or English

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: HIGH Altitude CArdiovascular REsearch in the ANDES
Brief Summary: This study is aimed to assess the efficacy of combined treatment with two antihypertensive agents (telmisartan and nifedipine) in subjects with mild hypertension exposed to high altitude.


Options:
A: Inclusion Criteria:

* At least one previous episode of high altitude pulmonary edema

Exclusion Criteria:

* pulmonary arterial hypertension
* congenital heart disease
* any chronic lung disease
B: Inclusion Criteria:

* Healthy, physically fit subject
* Mountaineering experience

Exclusion Criteria:

* Any type of cardiac or respiratory disease
* Regular intake of any medication
* History of high altitude pulmonary oedema
* Severe acute mountain sickness at altitudes below 3500m or high altitude cerebral oedema.
C: Inclusion Criteria:

* Participant in Apex 2 high altitude expedition

Exclusion Criteria:

* Previous history of high altitude pulmonary edema
D: Inclusion Criteria:

* Permanent residence at low (\<500 m) altitude
* Conventional systolic BP (average of two measurements) 140-159 mmHg or conventional diastolic BP 90-99 mmHg in subjects untreated or after 4 weeks of washout
* Mean daytime systolic BP ≥135 and \<150 mmHg and/or mean daytime diastolic BP ≥85 and \<95 mmHg in subjects untreated or after 4 weeks of washout
* Written informed consent to participate in the study

Exclusion Criteria:

* Conventional systolic BP (average of two measurements) ≥150 mmHg and conventional diastolic BP ≥95 mmHg in treated subjects
* Regular use of two or more antihypertensive drugs (with the exception of subjects on two antihypertensive drugs in low doses)
* Treated antihypertensive subjects in whom withdrawal of treatment is deemed unethical by the investigator (e.g. because of the existence of compelling indications other than hypertension for continuous use of previously used antihypertensive agent)
* Contraindications (including a history of adverse reactions) to angiotensin receptor blockers or calcium antagonists
* History of serious mountain sickness
* Subjects who over 3 months preceding inclusion in the study spent considerable (\> 1 week) amount of time at altitudes above 2500 m.
* Cardiovascular diseases other than hypertension (coronary heart disease, heart failure, atrial fibrillation, valvular or congenital heart disease, cardiomyopathies, cerebrovascular disease, peripheral artery disease, aortic aneurysm)
* Suspected or confirmed secondary hypertension
* Diabetes mellitus
* Serious respiratory disorders
* Other conditions deemed relevant by the investigator (including liver disease, renal disease, thyroid disorders)
* BMI ≥35 kg/m2
* Upper arm circumference \>32 cm
* known severe obstructive sleep apnea (apnea-hypopnea index \> 30 or use of CPAP) or excessive daytime sleepiness (Epworth Sleepiness Scale \> 10)
* Pregnancy
* Premenopausal women not using effective contraceptive methods
* Elevated probability of noncompliance with the study procedures

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Collagen Cross-linking in Infectious Keratitis Trial
Brief Summary: The purpose of this study is to evaluate the efficacy of collagen cross-linking for treatment of infectious keratitis.


Options:
A: Inclusion Criteria:

* Evidence of corneal ulcer grade II or III (bacteria or fungal, or presumed bacterial or fungal)
* Age more than 6 year
* Patients can understand and can follow the study protocol

Exclusion Criteria:

* Pregnancy by history or urine test
* Evidence of herpetic keratitis
* Evidence of corneal perforation
* Evidence of autoimmune disease
* Known allergy to study medication
B: Inclusion criteria:

* Corneal ulcer that is smear positive for either bacteria or filamentous fungus
* Pinhole visual acuity worse than 20/70 in the affected eye
* Not treated already with antimicrobial medications at presentation
* Age over 18 years
* Basic understanding of the study as determined by the physician
* Commitment to return for follow up visits

Exclusion criteria:

* Evidence of concomitant infection on exam or gram stain (i.e. herpes, both bacteria and acanthamoeba on gram stain)
* Impending or frank perforation at recruitment
* Involvement of sclera at presentation
* Non-infectious or autoimmune keratitis
* History of corneal transplantation or recent intraocular surgery
* No light perception in the affected eye
* Pinhole visual acuity worse than 20/200 in the unaffected eye
* Participants who are decisionally and/or cognitively impaired
C: Inclusion Criteria:

* Candidate for KPro type I
* Capacity to give written consent
* Ability to be followed for the duration of the study

Exclusion Criteria:

* Participation in another interventional study
* Failure to wear a therapeutic contact lens due to abnormalities of the eyelids.
* Inability to give written consent

Contraindications to the KPro type I:

* Severe dryness with keratinization of the ocular surface
* Intraocular tumor
* Terminal glaucoma
* Inoperable retinal detachment
* Phthisis bulbi
D: Inclusion Criteria:

* Infectious bacterial or fungal keratitis with : size \> 2mm or within the central corneal area ( 3mm of the visual axis ) or with a reaction in anterior chamber.
* Being major responsible.
* Agreement in writing to participate in the study.
* Being affiliated to a national insurance scheme.

Exclusion Criteria:

* Present an infectious keratitis without all the previous criteria.
* Herpes or acanthamoeba keratitis
* preperforated or perforated cornea.

General criteria:

* Pregnant woman.
* Minors(miners).
* Adults under guardianship.
* Patient can not be followed during 3 necessary months.
* French speaking patient.
* Unaffiliated patient in a national insurance scheme.
* HIV infected patients

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Health Impact Evaluation of the "Community-Based Environmental Health Promotion Programme" in Rwanda
Brief Summary: Community Health Clubs to improve local sanitation, hygiene and health conditions have been implemented in several countries in Africa and Asia with some success. The Ministry of Health in Rwanda has committed to rolling out a program designed along similar lines, the Community Based Environmental Health Promotion Program (CBEHPP), in all 15000 villages across Rwanda. The main objective of the program is to achieve 'zero open defecation' in all villages of Rwanda, at least 80% hygienic latrine coverage and improvements in a range of health behaviors such as the use of mosquito nets, hand-washing with soap and the use of household water treatment.

To evaluate the impact of the program on health, other socio-economic outcomes and community functioning, a single district has been chosen where 150 communities will be randomized to receive the intervention immediately or 18 months later. The evaluation is led by US based Innovation for Poverty Action (IPA) through researchers based at the National University of Rwanda, Georgetown University, London School of Hygiene and Tropical Medicine and New York University. The research team will work in close collaboration with the implementing team, which consists of the Ministry of Health, Rwanda and Africa AHEAD.

The study will span three years, beginning in May 2013, and ending in late 2015.


Options:
A: Inclusion Criteria:

* female
* 13-22 years old
* never married
B: Inclusion Criteria:

* Mother of child between the ages of 3 and 12 months and her child

Exclusion Criteria:

* N/A
C: Inclusion Criteria:

-All households with children under 5 years in the study communities are eligible for socio-economic and health outcome evaluation.

Exclusion Criteria:

-All households are eligible to participate in the intervention. However, for the purposes of the study, households with no children under the age of 5 will not be selected for data collection purposes.
D: Inclusion Criteria:

* HIV-infected
* 18-49 years old
* Currently receiving HAART
* Belong to a patient support group or demonstrate willingness to join a support group.
* Have access to farming land and available surface water
* Have evidence of food insecurity, hunger and/or malnutrition (BMI\<18.5 kg) based on FACES medical records during the year preceding recruitment.
* Participants must also agree to save the down payment (\~$7) required for the loan, participate in the Adok Timo training.

Exclusion Criteria:

* None

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Primaquine's Gametocytocidal Efficacy in Malaria Asymptomatic Carriers Treated With Dihydroartemisinin-piperaquine in The Gambia
Brief Summary: In this study, the investigators are interested to know if lower doses of Primaquine together with dihydroartemisinin-piperaquine can produce a similar effect of clearing both sexual and asexual parasites in asymptomatic carriers compared to the recommended dose of primaquine but with a decreased risk of haemolysis.

Children (\> 1 year) and adults with normal Glucose-6-phosphate dehydrogenase enzyme levels but with asexual Plasmodium falciparum parasites on the day of screening will be invited to take part in this study.


Options:
A: Inclusion Criteria:

* Age of 1 year and above and neither pregnant nor breast feeding.
* Weight over 10 kg.
* Body temperature ≥37.5°C) or history of fever in the last 24 hours.
* P. falciparum mono-infection.

Exclusion Criteria:

* Evidence of severe illness malaria or danger signs.
* Known allergy to study medications.
* Hemoglobin \<8 g/dl.
* Antimalarials taken within last 2 weeks.
* Blood transfusion within last 90 days and evidence of recent use (within 14 days)of or will be taking other drugs known to cause hemolysis in G6PD deficient subjects.
B: Inclusion Criteria:

* infection with P.falciparum detected by PCR

Exclusion Criteria:

* pregnancy
* severe anaemia
* fever or other signs of illness
* history of allergy to sulfa drugs
* presence of other species of Plasmodium detected by microscopy
C: Inclusion Criteria:

Age ≥1 year

* Weight \>10 Kg
* P. falciparum mono-infection, density of at least 20 parasites/μL
* Axillary temperature \< 37.5ºC
* Resident in the study area and willingness to reside for the duration of the study
* Written informed consent (plus an assent in children \>12years of age)

Exclusion Criteria:

* G6PD Deficiency Haemoglobin \<8g/dl

  * Known allergy to any of the study medications
  * Known Pregnancy or breastfeeding
  * Clear/documented history of anti-malarial treatment 2 weeks before contact with study team
  * History of blood transfusion in the previous 3 months
  * Any chronic or acute conditions that might interfere with the study as judged by the research clinician
  * History of sickle cell anaemia
D: Inclusion Criteria:

* Male
* Age \>= 18 years and \< 50 years
* Malaria blood thick film positive
* Presence of gametocytes on thick blood film
* Agrees to admission to study ward for 26 hours post diagnosis and available for follow up visits
* No allergies to study drugs
* Hemoglobin \>= 8 g/dl
* No evidence of severe or chronic disease
* Written, informed consent

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Guiding Dreaming During Anaesthesia by Means of Communication Through Suggestions. What Influences Our Suggestions? What do Our Suggestions Influence?
Brief Summary: Hypothesis: By employing suggestions before the induction of narcosis dreams may be evoked and their content may be directed.

The main goal of suggestive techniques in the perioperative phase is to turn the content of dreams toward a favourable direction that is considered a pleasant event by the patient. So far little attention has been paid to the administration of perioperative psychological methods that may meet these requirements.

Along these lines, in the present study we intended to assess whether dream recalls can be influenced by two different psychological methods administered in the preoperative setting


Options:
A: Inclusion Criteria:

* Age range 18-75-years
* English or Icelandic speaking
* Cognitively alert and oriented to person, place, time, and situation
* Intact visual and auditory senses

Exclusion Criteria:

* History of substance abuse
* Chronic pain lasting more than six months
* Use of narcotic medication for more than six months
* Major psychiatric disorders
* Taking prescribed medications for thought disorders
* Having ophthalmology and/or auditory surgery or impairments
B: Inclusion Criteria:

* planned elective laparoscopic cholecystectomy at Manukau Surgical Centre
* able to understand English
C: Inclusion Criteria:

* with whom verbal communication was possible.
* After a written informed consent, written agreement was obtained

Exclusion Criteria:

* mental retardation
* tracheotomy
* inability to communicate
D: Inclusion Criteria:

* Patients who have been accepted for bariatric surgery

Exclusion Criteria:

* Patients suffering from drug and/or alcohol addiction.

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Mothers in Motion Program to Prevent Weight Gain in Overweight/Obese WIC Mothers (MIM)
Brief Summary: Mothers in Motion will draw on the successes of the pilot intervention of the same name and will promote healthy lifestyle behavior changes (eating more fruits and vegetables, increasing physical activity, dealing with stress) in low-income WIC mothers of young children. The intervention group's weight change (difference between the initial enrollment and 3 months post intervention) will differ from the control group's weight change by an average of at least 2.8 pounds.


Options:
A: Inclusion Criteria:

* Participants will be European American or Mexican American residents of Corpus Christi, Texas area and member of a Catholic Church participating in the study
* greater than 18 years of age
* speak English or Spanish
* willing to provide a mailing address and home telephone number to study personnel at the time of consent
* participants must be able to identify a friend or family partner who is also willing to participate in the study
* to avoid second level clustering, only two individuals per household (the first to enroll) will be eligible

Exclusion Criteria:

* Known pregnancy is an exclusion criterion.
B: Inclusion Criteria:

* African American or White
* Fluent in English
* 18-39 years old
* At least 6 weeks postpartum
* Body Mass Index (BMI) between 25.0 and 39.9
* Willing to provide address and up to 3 working phone numbers
* Willing to update their contact information monthly
* Willing to participate in the project for 9 months
* Willing to make 3 additional trips to WIC clinics for weight measures
* Working DVD player at home and access to a working phone.

Exclusion Criteria:

* Pregnant
* MIM Pilot study participation
* Plan to become pregnant or relocate to a location outside of study area during the trial
* Self-reported type 1 or 2 Diabetes
* Unable to walk more than 1 block without resting or shortness of breath.
C: Inclusion Criteria:

* Female
* Ages 25 and over
* BMI 25 and over
* English fluency
* Not currently pregnant
* No restrictions to ambulatory activity

Exclusion Criteria:

* Current pregnancy
* Childbearing in the past 12 months
* History of myocardial infarction or stroke in last 2 years
D: Patients that will be included into the study if they have either / or

* Diagnosed with Pre-Diabetes (IGT or IFG)
* Aged 40 - 75 if English speaking European or 25 - 75 if South Asian
* Able to attend group education sessions

Exclusion Criteria:

Patients will be excluded from the study if they are:

* Unable to give consent
* Unable to attend group education sessions
* Diagnosis of diabetes at screening or during the study
* Require an interpreter for language other than South Asian

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Health Promotion Coaching/Vaccine for Homeless Parolees
Brief Summary: The purpose of this study is to conduct a prospective, three-group study that randomly assigns 700 parolees, in a community residential drug treatment program, to enter one of three groups: 1) a PCPC (Parolee Comprehensive Care + Phone Coaching Program), which includes nurse case management and specialized hepatitis education sessions and the hepatitis A/B (HAV/HBV) vaccination series (to all eligible) and coach-facilitated mentoring (mostly by cell-phone); 2) a Parolee Brief Hepatitis Education + HBV vaccination + Phone Coaching (PBCP) Program, which includes brief hepatitis/HIV education, HAV/HBV vaccination and coach-facilitated mentoring; or 3) a Usual Care (UC) control program, which includes brief general health information, one-on-one coaching and the HAV/HBV vaccine.


Options:
A: Inclusion Criteria:

* female parolees or probationers enrolled in a six-month program at one of two residential treatment (RDT) programs,
* convicted for a drug crime, and
* reported homeless on their RDT entry form

Exclusion Criteria:

* female parolees or probationers not currently enrolled in a six-month program at one of two residential treatment (RDT) programs,
* not recently convicted for a drug crime, and
* not reported homeless on their RDT entry form
B: Inclusion Criteria:

1. Parolees enrolled in Amity's Amistad's program;
2. Age 18-60;
3. Discharged from prison or jail within the last six months;
4. History of drug use 12 months prior to most recent incarceration;
5. Previously homeless prior to most recent incarceration; and
6. Willing to provide informed consent

Exclusion Criteria:

1. Monolingual speakers of languages other than English; and
2. Persons judged to be cognitively impaired by the research staff.
C: Inclusion Criteria:

* qualify for a DSM-IV lifetime diagnosis of cocaine dependence and cocaine use in 6 months prior to treatment;
* initial engagement in IOP, as indicated by attendance at 4 or more sessions in the first two weeks of treatment;
* 18 to 75 years of age;
* willingness to be randomized and participate in research.
* metropolitan area residents;
* able to provide the name, verified telephone number, and address of at least one contact who can provide locator information on the patient during follow-up.

Exclusion Criteria:

* current psychotic disorder or evidence of dementia severe enough to prevent participation in outpatient treatment;
* acute medical problem requiring immediate inpatient treatment;
* current participation in methadone or other forms of DA treatment, other than IOP
D: Inclusion Criteria:

* Women aged 18-64 years
* Patients at the health care site
* Able to participate in English
* Able to separate from accompanying person(s)

Exclusion Criteria:

* Too ill to participate
* Unable to separate from accompanying person(s)
* Unable to speak, read, or write English

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Randomized Trial Comparing Robotic and Abdominal Surgery for High Risk Endometrial Cancer
Brief Summary: This study is intended to explore differences in oncologic and surgical safety between robotic assisted laparoscopy and conventional abdominal surgery for high risk endometrial cancer.


Options:
A: Inclusion Criteria:

* 18-75 years of age
* High risk endometrial cancer

Exclusion Criteria:

* WHO performance\>1
* Severe comorbidity, ASA\>3
* Unable to understand information
B: Inclusion Criteria:

* Indication for laparoscopic hysterectomy
* Patients BMI \< 40
* Signed consent

Exclusion Criteria:

* Estimated uterus weight \>400 g
* No combination with other procedures
* No underlying malignant condition
C: Inclusion Criteria:

1. Stage II to IV pelvic organ prolapse
2. Prolapse of the vaginal apex or cervix to at least half way into the vaginal canal
3. Vaginal bulge symptoms
4. Minimally invasive surgery is planned
5. Available for 12 months of follow-up
6. Able to complete study assessments
7. Able and willing to provide written informed consent

Exclusion Criteria:

1. Contraindication to laparoscopic or robotically assisted laparoscopic abdominal sacrocolpopexy
2. Subject wishes to retain her uterus (i.e., surgical assignment may involve removal of uterus, if not previously removed)
D: Inclusion Criteria:

* Diagnosis of endometrial cancer confirmed by histopathological analysis (endometrial biopsy) requiring surgical staging according to FIGO (the International Federation of Gynecology and Obstetrics) recommendations
* Diagnosis of ovarian cancer confirmed by histopathological analysis after an initial cystectomy or oophorectomy without suspicion of neoplasia thus requiring additional surgical staging according to FIGO recommendations

Exclusion Criteria:

* Diagnosis of advanced endometrial cancer based on findings on imaging techniques (CT, MRI and/or PET)
* Diagnosis of advanced endometrial or ovarian cancer based on intraoperative findings (e.g. peritoneal carcinomatosis at initial laparoscopy)
* Patients who underwent previous aortic lymphadenectomy
* Patients who received previous pelvic and/or aortic radiotherapy

Answer: A