Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Fluid Lavage of Open Wounds (FLOW): A Multi-center, Blinded, Factorial Trial Comparing Alternative Irrigating Solutions and Pressures in Patients With Open Fractures
Brief Summary: Open fracture wounds are a constant challenge to orthopaedic surgeons, with infections a common complication. There is currently little evidence as to which is the most effective way to wash out these wounds. This study is a multi-center, prospective, randomized study. The infection rates will be compared between irrigation using high pressure versus low pressure versus gravity flow, and also saline versus a soap solution as the irrigation solution. The results from this study will help to determine the best method of washing out open fractures wounds. In this study, all open wounds will be washed out using methods commonly used by orthopaedic surgeons


Options:
A: Arm Label: SILS; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Single Incision Laparoscopic Appendectomy | Arm Label: 3 port; Type: ACTIVE_COMPARATOR; Interventions: Procedure: 3 port laparoscopic appendectomy | Intervention Type: PROCEDURE; Name: Single Incision Laparoscopic Appendectomy; Assigned to Arm(s): SILS | Intervention Type: PROCEDURE; Name: 3 port laparoscopic appendectomy; Assigned to Arm(s): 3 port
B: Arm Label: Saline, gravity flow; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Saline Solution, Procedure: Gravity Flow Irrigation | Arm Label: Saline, Low Pressure; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Saline Solution, Procedure: Low Pressure Irrigation | Arm Label: Saline, High Pressure; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Saline Solution, Procedure: High Pressure | Arm Label: Soap, Gravity Flow; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Soap solution, Procedure: Gravity Flow Irrigation | Arm Label: Soap, low pressure; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Soap solution, Procedure: Low Pressure Irrigation | Arm Label: Soap, high pressure; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Soap solution, Procedure: High Pressure | Intervention Type: PROCEDURE; Name: Saline Solution; Assigned to Arm(s): Saline, High Pressure, Saline, Low Pressure, Saline, gravity flow | Intervention Type: PROCEDURE; Name: Soap solution; Assigned to Arm(s): Soap, Gravity Flow, Soap, high pressure, Soap, low pressure | Intervention Type: PROCEDURE; Name: Gravity Flow Irrigation; Assigned to Arm(s): Saline, gravity flow, Soap, Gravity Flow | Intervention Type: PROCEDURE; Name: Low Pressure Irrigation; Assigned to Arm(s): Saline, Low Pressure, Soap, low pressure | Intervention Type: PROCEDURE; Name: High Pressure; Assigned to Arm(s): Saline, High Pressure, Soap, high pressure
C: Arm Label: Gentamicin lavage; Type: EXPERIMENTAL; Interventions: Drug: Axillary lavage with gentamicin solution | Arm Label: Normal saline lavage; Type: ACTIVE_COMPARATOR; Interventions: Drug: Axillary lavage with gentamicin solution | Intervention Type: DRUG; Name: Axillary lavage with gentamicin solution; Assigned to Arm(s): Gentamicin lavage, Normal saline lavage
D: Arm Label: intraoperative colon lavage; Type: EXPERIMENTAL; Interventions: Procedure: intraoperative colon lavage with primary anastomosis | Arm Label: stent and deferred surgery; Type: ACTIVE_COMPARATOR; Interventions: Procedure: intraoperative colon lavage with primary anastomosis | Intervention Type: PROCEDURE; Name: intraoperative colon lavage with primary anastomosis; Assigned to Arm(s): intraoperative colon lavage, stent and deferred surgery

Answer: B