TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Beyond Silence: Comparing the Impact of Contact-based Education With Mental Health Literacy Training on Early Intervention for Healthcare Workers With Mental Health Issues
Brief Summary: The purpose of this study is to compare the impact of a new workplace-based mental health peer education program with standardized mental health literacy training on early intervention and support for healthcare employees with mental health issues. Participants are healthcare workers who volunteer to participate in one of the two twelve-hour group education programs. It is hypothesized that the customized "Beyond Silence" peer education program led by trained staff members with personal experience of mental ill-health will be more effective in reducing the stigma associated with help-seeking and help-outreach regarding mental ill-health in the workplace. The comparison group is a standardized mental health literacy training program that has been widely implemented in both Canada and around the world. Change in help-seeking/help-outreach behavior, mental health knowledge and beliefs of participants will be assessed at three-month intervals; before, after and three months following the educational intervention.


Options:
A: Arm Label: Training course; Type: EXPERIMENTAL; Interventions: Other: Mental Health First-aid | Arm Label: Waiting list; Type: OTHER; Interventions: Other: Mental Health First-aid | Intervention Type: OTHER; Name: Mental Health First-aid; Assigned to Arm(s): Training course, Waiting list
B: Arm Label: Mental Health First Aid Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Mental Health First Aid | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Mental Health First Aid; Assigned to Arm(s): Mental Health First Aid Intervention
C: Arm Label: Pure control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Intervention residence on mixed campus; Type: EXPERIMENTAL; Interventions: Behavioral: Mental Health First Aid | Arm Label: Pure intervention residence; Type: EXPERIMENTAL; Interventions: Behavioral: Mental Health First Aid | Arm Label: Control at mixed campus; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Mental Health First Aid; Assigned to Arm(s): Intervention residence on mixed campus, Pure intervention residence
D: Arm Label: Contact-based mental health education; Type: EXPERIMENTAL; Interventions: Behavioral: Beyond Silence | Arm Label: Mental health literacy training; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Mental Health First Aid (MHFA) | Intervention Type: BEHAVIORAL; Name: Beyond Silence; Assigned to Arm(s): Contact-based mental health education | Intervention Type: BEHAVIORAL; Name: Mental Health First Aid (MHFA); Assigned to Arm(s): Mental health literacy training

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Postoperative Complication and Hospital Stay Reduction With a Individualized Perioperative Lung Protective Ventilation. A Comparative, Prospective, Multicenter, Randomized Controlled Trial.
Brief Summary: The purpose of this study is to determine whether individualized ventilatory management combining the use of low tidal volumes, alveolar recruitment maneuvers, individually titrated positive end-expiratory pressure and postoperative individualized ventilatory support will decrease postoperative complications, unplanned ICU readmissions, ICU and hospital length of stay and mortality compared to a standardized Lung Protective Ventilation (LPV) for all patients at risk.


Options:
A: Intervention Type: OTHER; Name: Mild intraoperative hypercapnia (50 mmHg vs. 30 mmHg); Assigned to Arm(s): N/A | Intervention Type: OTHER; Name: Supplemental oxygen (80% vs. 30%); Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Dexamethasone; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): N/A
B: Arm Label: high VT group; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Low tidal volume; Type: EXPERIMENTAL; Interventions: Procedure: Low tidal volume, Other: low tidal volume | Intervention Type: PROCEDURE; Name: Low tidal volume; Assigned to Arm(s): Low tidal volume | Intervention Type: PROCEDURE; Name: Low tidal volume; Assigned to Arm(s): Low tidal volume | Intervention Type: OTHER; Name: low tidal volume; Assigned to Arm(s): Low tidal volume
C: Arm Label: Low tidal volume; Type: EXPERIMENTAL; Interventions: Other: Ventilation Strategy | Arm Label: Usual care; Type: ACTIVE_COMPARATOR; Interventions: Other: Ventilation Strategy | Intervention Type: OTHER; Name: Ventilation Strategy; Assigned to Arm(s): Low tidal volume, Usual care
D: Arm Label: Individualized ventilation; Type: EXPERIMENTAL; Interventions: Procedure: Alveolar recruitment maneuver, Procedure: Calculation of optimal PEEP | Arm Label: Individualized vent. + postop. CPAP; Type: EXPERIMENTAL; Interventions: Procedure: Alveolar recruitment maneuver, Procedure: Calculation of optimal PEEP, Procedure: Postoperative CPAP | Arm Label: Standard ventilation; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Standard vent. + postoperative CPAP; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Postoperative CPAP | Intervention Type: PROCEDURE; Name: Alveolar recruitment maneuver; Assigned to Arm(s): Individualized vent. + postop. CPAP, Individualized ventilation | Intervention Type: PROCEDURE; Name: Calculation of optimal PEEP; Assigned to Arm(s): Individualized vent. + postop. CPAP, Individualized ventilation | Intervention Type: PROCEDURE; Name: Postoperative CPAP; Assigned to Arm(s): Individualized vent. + postop. CPAP, Standard vent. + postoperative CPAP

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multicentric Prospective Randomised Single-blind Controlled Clinical Study Assessing the Effect and the Safety of Primebrain Sensorimotor Stimulation on Neurological Development of Preterm Infants (Born Before 32 Weeks' Gestation) or Infants Born Weighing Less Than 1500 g
Brief Summary: Background : Brain vulnerability is particularly marked in preterm neonates and has long-term consequences. Unlike lesions affecting other organs, those that affect the brain can currently not 'be repaired' by producing new cells. However, exeprience-driven brain plasticity allows the brain to reorganise its connections to compensate (at least partially) the effects of an injury.

Purpose : To evaluate the influence of Primebrain stimulation programme administred by parents until 6 months post-term on motor and neurophysiological development of infants born \<32 weeks' gestation or with birth weight \<1500 g.


Options:
A: Arm Label: Primebrain; Type: EXPERIMENTAL; Interventions: Other: Primebrain | Arm Label: usual care; Type: OTHER; Interventions: Other: Primebrain | Intervention Type: OTHER; Name: Primebrain; Assigned to Arm(s): Primebrain, usual care
B: Arm Label: Early stimulation; Type: EXPERIMENTAL; Interventions: Other: Early stimulation | Arm Label: Conventional care; Type: ACTIVE_COMPARATOR; Interventions: Other: Conventional care | Intervention Type: OTHER; Name: Early stimulation; Assigned to Arm(s): Early stimulation | Intervention Type: OTHER; Name: Conventional care; Assigned to Arm(s): Conventional care
C: Arm Label: Individually customized physiotherapy; Type: OTHER; Interventions: Other: Individually customized physiotherapy | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Individually customized physiotherapy; Assigned to Arm(s): Individually customized physiotherapy
D: Arm Label: CareToy Intervention; Type: EXPERIMENTAL; Interventions: Device: CareToy intervention | Arm Label: Infant Massage; Type: ACTIVE_COMPARATOR; Interventions: Other: Infant Massage | Intervention Type: DEVICE; Name: CareToy intervention; Assigned to Arm(s): CareToy Intervention | Intervention Type: OTHER; Name: Infant Massage; Assigned to Arm(s): Infant Massage

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: RISE (Rehabilitation Intervention for People With Schizophrenia in Ethiopia): a Cluster-randomised Trial
Brief Summary: The purpose of this study is to determine whether community-based rehabilitation plus facility-based care is superior to facility-based care alone in reducing disability related to schizophrenia in rural Ethiopia.


Options:
A: Arm Label: Psychosocial counseling; Type: N/A; Interventions: N/A | Arm Label: Medication; Type: N/A; Interventions: N/A
B: Arm Label: Community-based rehabilitation and facility based care; Type: EXPERIMENTAL; Interventions: Behavioral: Community-based rehabilitation, Other: Facility based care | Arm Label: Facility-based care; Type: ACTIVE_COMPARATOR; Interventions: Other: Facility based care | Intervention Type: BEHAVIORAL; Name: Community-based rehabilitation; Assigned to Arm(s): Community-based rehabilitation and facility based care | Intervention Type: OTHER; Name: Facility based care; Assigned to Arm(s): Community-based rehabilitation and facility based care, Facility-based care
C: Arm Label: Depression Care; Type: EXPERIMENTAL; Interventions: Combination Product: evidence-based depression treatment | Arm Label: Usual care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: COMBINATION_PRODUCT; Name: evidence-based depression treatment; Assigned to Arm(s): Depression Care
D: Arm Label: Philani Intervention Program; Type: EXPERIMENTAL; Interventions: Behavioral: Philani Intervention Program | Arm Label: Standard Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Philani Intervention Program; Assigned to Arm(s): Philani Intervention Program

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Evaluating the Impact of Year Long, Augmented Diabetes Self Management Support
Brief Summary: Improving diabetes social support is associated with health improvement benefits. This study is a prospective randomized controlled trial comparing the effects of telephone-based diabetes self-management support (DSMS) compared with usual care, which includes diabetes self-management education (DSME), during a 1-year period. It will determine whether this specific model for providing on-going support to people with diabetes will better enable them to maintain the engagement in self-care behaviors, clinical improvements and diabetes-specific knowledge gained during the course of diabetes self-management education.


Options:
A: Arm Label: Exercise group; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise group | Arm Label: Usual care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Exercise group; Assigned to Arm(s): Exercise group
B: Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Treatment as usual | Arm Label: A; Type: EXPERIMENTAL; Interventions: Behavioral: Nurse-led case management | Intervention Type: BEHAVIORAL; Name: Nurse-led case management; Assigned to Arm(s): A | Intervention Type: BEHAVIORAL; Name: Treatment as usual; Assigned to Arm(s): B
C: Arm Label: usual care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: diabetes self management support; Type: ACTIVE_COMPARATOR; Interventions: Other: diabetes self management support | Intervention Type: OTHER; Name: diabetes self management support; Assigned to Arm(s): diabetes self management support
D: Arm Label: Enhanced Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Staged Care Management; Type: EXPERIMENTAL; Interventions: Behavioral: Medication Care Management (MCM), Behavioral: Cognitive-Behavioral Therapy (CBT) | Intervention Type: BEHAVIORAL; Name: Medication Care Management (MCM); Assigned to Arm(s): Staged Care Management | Intervention Type: BEHAVIORAL; Name: Cognitive-Behavioral Therapy (CBT); Assigned to Arm(s): Staged Care Management

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Transversus Abdominis Plane Block Versus Caudal Epidural for Lower Abdominal Surgery in Children: A Double-Blinded Randomized Controlled Trial
Brief Summary: Transversus abdominis plane block (TAPB) has emerged as a safe and effective regional anesthesia technique for providing postoperative lower abdominal analgesia. Complications associated with TAPB are very rare and pose a lower overall risk to the patient receiving a TAPB versus a caudal block, which is considered the gold standard for pediatric lower abdominal regional anesthesia. Our study hypothesis was that TAPB would be equivalent to caudal block initially in providing postoperative pain control but would show improved pain relief beyond the anticipated caudal duration.


Options:
A: Arm Label: Regional block; Type: EXPERIMENTAL; Interventions: Procedure: bilateral ultrasound-guided rectus sheath block | Arm Label: Wound infiltration; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Wound infiltration | Intervention Type: PROCEDURE; Name: bilateral ultrasound-guided rectus sheath block; Assigned to Arm(s): Regional block | Intervention Type: PROCEDURE; Name: Wound infiltration; Assigned to Arm(s): Wound infiltration
B: Arm Label: Treatment; Type: ACTIVE_COMPARATOR; Interventions: Drug: Levobupivacaine, Drug: Saline | Arm Label: Control group; Type: PLACEBO_COMPARATOR; Interventions: Drug: Levobupivacaine, Drug: Saline | Intervention Type: DRUG; Name: Levobupivacaine; Assigned to Arm(s): Control group, Treatment | Intervention Type: DRUG; Name: Saline; Assigned to Arm(s): Control group, Treatment
C: Arm Label: Quadratus Lumborum Block; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Quadratus Lumborum Block | Arm Label: Transversus abdominis plane block; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Transversus Abdominis Plane Block | Intervention Type: PROCEDURE; Name: Quadratus Lumborum Block; Assigned to Arm(s): Quadratus Lumborum Block | Intervention Type: PROCEDURE; Name: Transversus Abdominis Plane Block; Assigned to Arm(s): Transversus abdominis plane block
D: Arm Label: Transversus Abdominis Plane Block; Type: EXPERIMENTAL; Interventions: Procedure: Transversus Abdominis Plane Block | Arm Label: Caudal Epidural Block; Type: EXPERIMENTAL; Interventions: Procedure: Caudal Epidural | Intervention Type: PROCEDURE; Name: Caudal Epidural; Assigned to Arm(s): Caudal Epidural Block | Intervention Type: PROCEDURE; Name: Transversus Abdominis Plane Block; Assigned to Arm(s): Transversus Abdominis Plane Block

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Impact of Metadoxine in the Oxidative Stress and Early Mortality in Patients With Severe Alcoholic Hepatitis
Brief Summary: The purpose of this study is to determine whether metadoxine is effective for improve survival and reduced oxidative stress in patients with severe alcoholic hepatitis.


Options:
A: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Drug: pentoxifylline | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Drug: PLACEBO | Intervention Type: DRUG; Name: pentoxifylline; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: PLACEBO; Assigned to Arm(s): 2
B: Arm Label: Prednisone; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Pentoxifylline; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Prednisone plus metadoxine; Type: EXPERIMENTAL; Interventions: Drug: Prednisone plus Metadoxine | Arm Label: Pentoxifylline plus metadoxine; Type: EXPERIMENTAL; Interventions: Drug: Pentoxifylline plus Metadoxine | Intervention Type: DRUG; Name: Prednisone plus Metadoxine; Assigned to Arm(s): Prednisone plus metadoxine | Intervention Type: DRUG; Name: Pentoxifylline plus Metadoxine; Assigned to Arm(s): Pentoxifylline plus metadoxine
C: Arm Label: Pentoxifylline + Prednisolone; Type: ACTIVE_COMPARATOR; Interventions: Drug: placebo | Arm Label: Placebo + Prednisolone; Type: PLACEBO_COMPARATOR; Interventions: Drug: Pentoxifylline | Intervention Type: DRUG; Name: Pentoxifylline; Assigned to Arm(s): Placebo + Prednisolone | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Pentoxifylline + Prednisolone
D: Arm Label: Corticoids plus N Acetyl Cysteine; Type: EXPERIMENTAL; Interventions: Drug: Corticoids plus N Acetyl Cysteine | Intervention Type: DRUG; Name: Corticoids plus N Acetyl Cysteine; Assigned to Arm(s): Corticoids plus N Acetyl Cysteine

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: An Investigator Initiated, International Collaborative, Multicentre, Cluster Crossover, Randomised Controlled Trial to Establish the Effects of Head Positioning on Death or Disability in Patients With Acute Stroke
Brief Summary: This study is an investigator-initiated and conducted, international collaborative, regionally organised, multicentre, prospective, cluster randomised, crossover, blinded outcome assessment study to compare the effectiveness of the lying flat (0°) head position with the sitting up (=30°) head position, in the first 24 hours of admission to hospital for patients with acute stroke, on the poor outcome of death or disability over the subsequent 90 days.


Options:
A: Arm Label: The lying flat intervention; Type: EXPERIMENTAL; Interventions: Other: The lying flat (0°) head position for 24 hours | Arm Label: The sitting-up intervention; Type: ACTIVE_COMPARATOR; Interventions: Other: The sitting-up (≥30°) head position for 24 hours | Intervention Type: OTHER; Name: The lying flat (0°) head position for 24 hours; Assigned to Arm(s): The lying flat intervention | Intervention Type: OTHER; Name: The sitting-up (≥30°) head position for 24 hours; Assigned to Arm(s): The sitting-up intervention
B: Arm Label: Early vertical positioning; Type: ACTIVE_COMPARATOR; Interventions: Other: Mobilization of stroke patients | Arm Label: Progressively vertical positioning; Type: ACTIVE_COMPARATOR; Interventions: Other: Mobilization of stroke patients | Intervention Type: OTHER; Name: Mobilization of stroke patients; Assigned to Arm(s): Early vertical positioning, Progressively vertical positioning
C: Arm Label: group 1: standard physiotherapy; Type: PLACEBO_COMPARATOR; Interventions: Procedure: standard physiotherapy | Arm Label: group 2: experimental physiotherapy; Type: EXPERIMENTAL; Interventions: Procedure: experimental physiotherapy | Intervention Type: PROCEDURE; Name: standard physiotherapy; Assigned to Arm(s): group 1: standard physiotherapy | Intervention Type: PROCEDURE; Name: experimental physiotherapy; Assigned to Arm(s): group 2: experimental physiotherapy
D: Arm Label: Standard Care; Type: PLACEBO_COMPARATOR; Interventions: Other: Standard care | Arm Label: Standard Care + VEM; Type: EXPERIMENTAL; Interventions: Other: Standard Care + VEM | Intervention Type: OTHER; Name: Standard Care + VEM; Assigned to Arm(s): Standard Care + VEM | Intervention Type: OTHER; Name: Standard care; Assigned to Arm(s): Standard Care

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Treatment Strategies in Colorectal Cancer Patients with Initially Unresectable Liver-only Metastases CAIRO5 a Randomized Phase 3 Study of the Dutch Colorectal Cancer Group (DCCG)
Brief Summary: Colorectal cancer patients with initially unresectable liver-only metastases may be cured after downsizing of metastases by neoadjuvant systemic therapy. However, the optimal neoadjuvant induction regimen has not been defined, and no consensus exist on criteria for resectability.

In this study colorectal cancer patients with initially unresectable liver-only metastases, as prospectively confirmed by an expert panel according to predefined criteria, will be tested for RAS and BRAF tumor mutation status and selected by location of primary tumor. Patients with RAS or BRAF mutant and/or right sided tumors will be randomised between doublet chemotherapy (FOLFOX or FOLFIRI) plus bevacizumab (schedule 1), and triple chemotherapy (FOLFOXIRI) plus bevacizumab (schedule 2). Patients with RAS AND BRAF wildtype AND left-sided primary tumors will be randomized between doublet chemotherapy (FOLFOX or FOLFIRI) plus either bevacizumab (schedule 1) or panitumumab (schedule 3). Patient imaging will be reviewed for resectability by a central panel, consisting of at least one radiologist and three surgeons every assessment. Central panel review will be performed prior to randomization as well as during treatment, as described in the protocol.


Options:
A: Intervention Type: DRUG; Name: ABX-EGF; Assigned to Arm(s): N/A
B: Arm Label: Arm B: FOLFOXIRI & bevacizumab (inclusion completed); Type: EXPERIMENTAL; Interventions: Drug: FOLFOXIRI with bevacizumab | Arm Label: Arm A: FOLFOX/FOLFIRI & bevacizumab (inclusion completed); Type: ACTIVE_COMPARATOR; Interventions: Drug: FOLFOX/ FOLFIRI with bevacizumab | Arm Label: Arm D: FOLFOX/FOLFIRI & panitumumab; Type: EXPERIMENTAL; Interventions: Drug: FOLFOX/ FOLFIRI with panitumumab | Arm Label: Arm C: FOLFOX/ FOLFIRI & bevacizumab; Type: ACTIVE_COMPARATOR; Interventions: Drug: FOLFOX/ FOLFIRI with bevacizumab | Intervention Type: DRUG; Name: FOLFOX/ FOLFIRI with bevacizumab; Assigned to Arm(s): Arm A: FOLFOX/FOLFIRI & bevacizumab (inclusion completed), Arm C: FOLFOX/ FOLFIRI & bevacizumab | Intervention Type: DRUG; Name: FOLFOXIRI with bevacizumab; Assigned to Arm(s): Arm B: FOLFOXIRI & bevacizumab (inclusion completed) | Intervention Type: DRUG; Name: FOLFOX/ FOLFIRI with panitumumab; Assigned to Arm(s): Arm D: FOLFOX/FOLFIRI & panitumumab
C: Arm Label: Arm A; Type: EXPERIMENTAL; Interventions: Drug: Cetuximab, Drug: chemotherapy of mFOLFOX6 or FOLFIRI | Arm Label: Arm B; Type: ACTIVE_COMPARATOR; Interventions: Drug: chemotherapy of mFOLFOX6 or FOLFIRI | Intervention Type: DRUG; Name: Cetuximab; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: chemotherapy of mFOLFOX6 or FOLFIRI; Assigned to Arm(s): Arm A, Arm B
D: Intervention Type: BIOLOGICAL; Name: cetuximab; Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: quality-of-life assessment; Assigned to Arm(s): N/A

Answer: B