Please select the eligibility criteria that correspond to the clinical trial below.
Title: Nordic DeltaCon Trial: Non-operative Treatment Versus Reversed Total Shoulder Prosthesis in Patients Sixty Five Years of Age and Older With Displaced 3- and 4 Parts Proximal Humeral Fractures - a Prospective, Randomized Controlled Trial
Brief Summary: The Nordic DeltaCon Trial is a prospective, single-blinded, randomized, controlled, multi-center and multi-national trial comparing reverse prosthesis and non-operative treatment in displaced proximal humerus fractures, in the elderly patients aged 65 to 85 years with displaced OTA/AO group B2 or C2 fractures (According to the new 2018 revision: AO/OTA (Orthopaedic Trauma Association) group 11-B1.1, 11-B1.2 and 11-C1.1, 11-C3.1. )


Options:
A: Inclusion Criteria:

* proximal humerus fracture of AO group B2 or C2 (displaced fracture of extra-articular or articular, bifocal type) admitted in hospital

Exclusion Criteria:

* aged less than 60 year
* patients of non-Scandinavian ethnicity
* previous history of injury or illness of the injured or contralateral shoulder
* injury of other part of the humerus or the contralateral upper extremity,
* alcohol- or drug abuse
* dementia or neurological diseases
* severe cardiovascular disease that would contraindicate surgery
B: Inclusion Criteria:

Low energy AO/OTA group 11-B1.1, 11-B1.2 and 11-C1.1, 11-C3.1. Both B and C type includes subgroups: Displaced \[2\], Impacted \[3\] or Non impacted \[4\] from the universal modifiers list.

Exclusion Criteria:

Radiographic Mal-inclination Less than; varus 30°or valgus 45° Less than 50% contact between head fragment and meta-/diaphysis Head split fractures with more than 10% of the articular surface in the main head fragment.

Head split fractures (group 11-C3.2 and 11-C3.3) with more than 10% of the articular surface in the main head fragment.

Dislocation or fracture-dislocation of the gleno-humeral joint Pathological fracture

General

* Refuse to participate
* Age under 65 years of age, or over 85 years of age
* Serious poly-trauma or additional surgery
* Non-independent, drug/alcohol abuse or institutionalized (low co-operation)
* Contra-indications for surgery
* Does not understand written and spoken guidance in local languages
* Previous fracture with symptomatic sequelae in either shoulder
* Patients living outside the hospital's catchment area
C: Inclusion Criteria:

* Displaced four-part fracture of the proximal humerus
* Mentally alert
* Physically fit for surgery and rehabilitation (ASA-group 1-3)
* Informed written consent
* Operation can be conducted within 2 weeks of injury

Exclusion Criteria:

* Fracture-dislocations
* Head-splitting fractures
* Previous shoulder surgery on injured side
* Chronic shoulder pain
* Abuse problems
* Patients unable to understand instructions in Danish
D: Inclusion Criteria:

* Age: ≤60 years or younger postmenopausal woman
* 2-fragment-fracture according to AO-classification AO 11-A3
* Signed informed consent
* Patient can read and understand German

Exclusion Criteria:

* Refusal to participate in the study
* Not Independent
* Dementia and/or institutionalized
* Does not understand written and spoken guidance German
* Pathologic fracture or a previous fracture of the same proximal humerus
* Alcoholism or drug addiction, e.g., in the emergency department, breathalyzer indicates blood alcohol concentration of more than 2%
* Other injury to the same upper limb requiring surgery
* Major nerve injury (e.g., complete radial- or axillary nerve palsy)
* Rotator cuff tear arthropathy
* Open fracture
* Multi-trauma or -fractured patient
* Fracture dislocation or head-splitting fracture
* Non-displaced fracture
* Isolated fracture of the major or minor tubercle
* Gross displacement of the fracture fragments (no bony contact between fracture parts or the humeral shaft is in contact with the articular surface)
* Any medical condition that excludes surgical treatment
* Pregnancy

Answer: B