Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Randomized, Double-blind, Comparative-effectiveness Study Comparing Epidural Steroid Injections to Gabapentin in Patients With Lumbosacral Radiculopathy
Brief Summary: The purpose of this study is to determine whether pharmacotherapy or epidural steroid injections are a better treatment for lumbosacral radicular pain.

142 patients referred to a participating pain clinic with lumbosacral radiculopathy will be randomized in a 1:1 ratio to receive one of two treatments. Half (n=71) of the patients will be allocated to receive an epidural steroid injection (ESI; group I), with an equal number allocated to receive gabapentin (group II). Patients \& evaluating physicians will be blinded. Follow-up will be through 3-months after treatment.


Options:
A: Arm Label: Gabapentin lower dose alone; Type: EXPERIMENTAL; Interventions: Drug: Gabapentin lower dose | Arm Label: Gabapentin higher dose alone; Type: ACTIVE_COMPARATOR; Interventions: Other: Placebo (Dop) | Arm Label: Gabapentin in combination with donepezil; Type: EXPERIMENTAL; Interventions: Drug: Donepezil, Drug: Gabapentin higher dose | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo (Gaba) | Intervention Type: DRUG; Name: Gabapentin lower dose; Assigned to Arm(s): Gabapentin lower dose alone | Intervention Type: DRUG; Name: Donepezil; Assigned to Arm(s): Gabapentin in combination with donepezil | Intervention Type: OTHER; Name: Placebo (Dop); Assigned to Arm(s): Gabapentin higher dose alone | Intervention Type: OTHER; Name: Placebo (Gaba); Assigned to Arm(s): Placebo | Intervention Type: DRUG; Name: Gabapentin higher dose; Assigned to Arm(s): Gabapentin in combination with donepezil
B: Arm Label: Epidural steroids; Type: EXPERIMENTAL; Interventions: Procedure: epidural steroid injection, Drug: Placebo gabapentin | Arm Label: Gabapentin; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Sham epidural steroid injection, Drug: Gabapentin | Intervention Type: PROCEDURE; Name: epidural steroid injection; Assigned to Arm(s): Epidural steroids | Intervention Type: PROCEDURE; Name: Sham epidural steroid injection; Assigned to Arm(s): Gabapentin | Intervention Type: DRUG; Name: Gabapentin; Assigned to Arm(s): Gabapentin | Intervention Type: DRUG; Name: Placebo gabapentin; Assigned to Arm(s): Epidural steroids
C: Arm Label: Pregabalin; Type: ACTIVE_COMPARATOR; Interventions: Drug: pregabalin | Arm Label: Duloxetine; Type: EXPERIMENTAL; Interventions: Drug: duloxetine hydrochloride | Arm Label: Gabapentin + Duloxetine; Type: EXPERIMENTAL; Interventions: Drug: duloxetine hydrochloride, Drug: gabapentin | Intervention Type: DRUG; Name: duloxetine hydrochloride; Assigned to Arm(s): Duloxetine, Gabapentin + Duloxetine | Intervention Type: DRUG; Name: pregabalin; Assigned to Arm(s): Pregabalin | Intervention Type: DRUG; Name: gabapentin; Assigned to Arm(s): Gabapentin + Duloxetine
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: gabapentin | Arm Label: 2; Type: SHAM_COMPARATOR; Interventions: Drug: Inert placebo | Intervention Type: DRUG; Name: gabapentin; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: Inert placebo; Assigned to Arm(s): 2

Answer: B