TrialPanorama/Dataset huggingface dataset:
Please select the eligibility criteria that correspond to the clinical trial below.
Title: High-flow Nasal Cannula Oxygen Versus Conventional Oxygen Therapy After Pulmonary Lobectomy
Brief Summary: The primary objective of this study is to evaluate the effect of early application of nasal high flow oxygen therapy after pulmonary lobectomy on the incidence of postoperative hypoxemia


Options:
A: Inclusion criteria:

* Age ≥ 18 years
* Cystic fibrosis as defined by clinical features in conjunction with 2 CF causing mutations and/or 2 sweat tests with sweat chloride \> 60 mmol/l
* Clinical indication for NIV based on at least one of the following criteria:

  * Signs of clinical respiratory distress - RR \> 24/min, accessory muscle use, or increased dyspnea
  * Progressive increase in arterial PCO2
  * Nocturnal hypoventilation treated by NIV but requiring daytime NIV because of clinical worsening

Exclusion criteria:

* Active massive hemoptysis
* Pneumothorax with pleural drainage and persistent air leak
* Hemodynamic instability requiring vasopressors
* Uncooperative
* Recent upper airway or esophageal surgery
* Patients with skin or chest wall or abdominal trauma
B: Inclusion Criteria:

* planned pulmonary lobectomy for lung cancer

Exclusion Criteria:

* age \<18 years
* patient refusal
* body mass index ≥35 kg/m2
* sleep apnea syndrome
* tracheostomy
* home oxygen therapy
* pregnancy
C: Inclusion Criteria:

* Acute respiratory insufficiency, defined as the PaO2/FIO2 ratio of 300 mm Hg or less after breathing oxygen
* The presence of lung infiltrates on a posteroanterior chest radiograph

Exclusion Criteria:

* Face or cranial trauma or surgery
* Patients younger than 18 years
* History of COPD
* Acute respiratory acidosis (defined as a pH \<7.30 and a PaCO2 \>50 mm Hg)
* Hemodynamic instability with arterial pressure \< 90mmHg
* Respiratory instability with PaO2/FiO2\<100mmHg
* ventricular arrhythmias
* Excess respiratory secretions.
* Upper gastrointestinal bleeding
* Recent gastric or oesophageal surgery
* Tracheostomy or other airways disorders
* Pneumothorax
* Contraindication of gastric probe insertion
* Impossibility to insert the oesophageal probe
D: Inclusion Criteria:

* Mechanical ventilation \> 24h
* Successful spontaneous breathing trial conducted for a period of 30-120 min.
* PaO2/FiO2 ≤ 300 at the end of the spontaneous breathing trial preceding extubation

Exclusion Criteria:

* age\<18 years
* pregnancy
* tracheostomy
* need of NIV post-extubation (prophylactic NIV)

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Optimizing Sedentary Behavior Interventions to Affect Acute Physiological
Brief Summary: An emerging body of epidemiological evidence suggests that various forms of sedentary behavior, including TV viewing, occupational sitting, and total daily sitting, may be associated with all-cause and cardiovascular mortality, overweight and obesity, type 2 diabetes, depression and psychological well-being. Importantly, many of these associations were independent of participation in moderate to vigorous intensity physical activity. We propose a pilot study to assess the feasibility, acceptability and preliminary efficacy of two interventions targeting sedentary behavior. Since it is currently unknown what component of sedentary behavior exposure presents the greatest risk to health, we propose separate interventions to reduce overall sedentary time and to promote breaks in sedentary time.


Options:
A: Inclusion Criteria:

* Employee of Janssen Pharmaceutics Belgium
* Physically inactive lifestyle (not reaching 150 minutes of moderate-to-vigorous physical activity a week)
* PAR-Q questionnaire all answers negative, if one or more answers are positive a permission of a physician is necessary

Exclusion Criteria:

* none
B: Inclusion Criteria:

1. Males or females 50 -70 years of age
2. Able to attend 4 measurement visits with study staff in 3 consecutive weeks
3. Spend at least 8 hours per day sitting
4. Willing and able to wear study device for 21 days
5. Able to read and write in English
6. Able to provide written informed consent

Exclusion Criteria:

1. Do not sit for at least 8 hours per day
2. Unable to attend 4 visits
3. Diagnosis of serious chronic condition that would limit the ability to stand
C: Inclusion Criteria:

* regional Northern California KP employees

Exclusion Criteria:

* none
D: Inclusion Criteria:

* Mostly sedentary (sitting ≥ 4 hour) during the workday.
* Age ≥ 18
* Anticipated using a single computer workstation for 20 hours or more per week

Exclusion Criteria:

* Unable to stand for at least two hours per workday (two hours over the whole workday, not consecutively)
* Reported severe musculoskeletal symptoms, specifically lower extremity or lower back pain.
* Diagnosed with or under treatment for diabetes, heart disease, cancer, orthostatic hypertension, varicose vein, autoimmune disease, or other chronic diseases.
* Pregnant women

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: HIV Point-of-Care Tests in Babies Study (BABY) - Operational Evaluation of HIV Point-of-Care Tests for Very Early Infant HIV Diagnostics in Infants Born to HIV Infected Mothers in Mbeya, Tanzania
Brief Summary: HIV Point-of-Care tests in Babies Study (BABY) - Operational evaluation of HIV Point-of-Care tests for very early infant HIV diagnostics in infants born to HIV infected mothers in Mbeya, Tanzania.


Options:
A: Inclusion Criteria:

* HIV-positive pregnant women enrolled in PMTCT services or who deliver at the study hospitals and/or mothers with exposed infants presenting for EID prior to 24 weeks
* Provide informed consent

Exclusion Criteria:

* HIV-positive pregnant women less than 18 years of age
* HIV-positive pregnant women unable to provide informed consent
* HIV-exposed infants presenting for HIV testing at \> 24 weeks
B: Inclusion Criteria:

1. Voluntary and informed consent of the mother for her own study participation (if applicable).
2. Voluntary and informed consent of the legal guardian of the child for participation of the child in the study.
3. Mothers/legal guardians ≥18 years of age.
4. Documented maternal HIV infection.
5. Willingness to consent to HIV testing for the child and herself (if applicable).
6. Willing to consent to active tracing including home tracing.

Exclusion Criteria:

1. Deficiency in the mother, rendering it difficult, if not impossible, for her or her infant to take part in the study or understand the information provided to her. This includes alcoholism, drug dependency as well as psychiatric illnesses, suicidal tendencies or any other inability.
2. Having delivered more than 48h ago
3. Prisoners
4. Women presenting with an emergency requiring immediate medical assistance if not resolved at study inclusion.
5. Stillbirths
6. Infant requiring emergency care or born with severe malformation.
7. If within the discretion of the investigator based on recommendation of the gynaecologist or paediatrician in charge study participation would possibly add not acceptable risk or burden to the mother or infant (e.g. significant congenital malformation, health deficiencies, very low birth weight less than 1500g)
8. Unlikely to comply with protocol as judged by the principal investigator or his designate
C: Inclusion Criteria:

* Primary Healthcare clinics located in rural and semi-rural settings

Exclusion Criteria:

* Primary Healthcare clinics located in urban settings
D: Inclusion Criteria:

* Born to HIV positive mother
* From 4 weeks to 18 months of age
* Came to CCR consultation for Early Infant Diagnosis

Exclusion Criteria:

* With a valid positive test by other center

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Isotonic Solutions and Major Adverse Renal Events Trial in Non-Medical Intensive Care Units
Brief Summary: The administration of intravenous fluids is ubiquitous in the care of the critically ill. Commonly available isotonic crystalloid solutions contain a broad spectrum electrolyte compositions including a range chloride concentrations. Recent studies have associated solutions with supraphysiologic chloride content with hyperchloremia, metabolic acidosis and renal vasoconstriction, acute kidney injury and renal replacement therapy, and increased mortality but no large, randomized-controlled trials have been conducted. SMART-SURG will be a large, cluster-randomized, multiple-crossover trial enrolling critically ill patients from the non-medical ICUs at Vanderbilt University from October 2015 until April 2017. The primary endpoint will be the incidence of Major Adverse Kidney Events in 30 days after enrollment (MAKE30 is the composite of death, new renal replacement, or persistent renal dysfunction at discharge).


Options:
A: Inclusion Criteria (all three):

1. Need for plasma expansion, and the clinician considers that Plasma-Lyte® or 0.9% saline are equally appropriate for patients, with no specific indications or contraindications for any of the fluids or for rapid or slow infusion.
2. Patients not expected to be discharged on the day after their admission.
3. At least one of the following risk factors for acute renal injury:

   1. Age ≥ 65 years
   2. Hypotension (mean arterial pressure \[MAP\] \< 65 mmHg or systolic blood pressure \[SBP\] \< 90 mmHg) or use of vasopressors
   3. Sepsis
   4. Use of invasive mechanical ventilation or of continuous noninvasive mechanical ventilation (including high-flow nasal cannula) \> 12 hours
   5. Oliguria (\< 0.5 mL/kg/hour for ≥ 3 hours)
   6. Serum creatinine ≥ 1.2 mg/dL for women or ≥ 1.4 mg/dL for men
   7. Liver cirrhosis or acute liver failure

Exclusion Criteria (any of the below):

1. Age \< 18 years
2. Acute renal failure treated with renal replacement therapy (RRT) or expected to require RRT within the next 6 hours
3. Severe hyponatremia (serum sodium ≤ 120 mmol/L)
4. Severe hypernatremia (serum sodium ≥ 160 mmol/L)
5. Death considered imminent and inevitable within 24 hours
6. Patients with suspected or confirmed brain death
7. Patients under exclusive palliative care
8. Patients previously enrolled in the BaSICS study
B: Inclusion Criteria:

* Admitted to the medical intensive care unit (ICU) at Vanderbilt University Medical Center

Exclusion Criteria:

* Age\<18 years old
C: Inclusion Criteria:

* Admitted to a participating non-medical intensive care unit (ICU) at Vanderbilt University Medical Center

Exclusion Criteria:

* Age\<18 years old
D: Inclusion Criteria:

Adult patients present in the ICU on the study day or admitted during the 24-hour study period will be included in the study sample.

Exclusion Criteria:

Children under 16 years are excluded

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Enhancing Physical Activity and Weight Reduction Through Smartcare and Financial Incentives: A Pilot Randomized Controlled Trial
Brief Summary: The investigators are planning to conduct a pilot RCT of young obese population to evaluate the effect of smartcare with or without financial incentives for 12 weeks. Participants will be randomly assigned to a three-arm of control, smartcare, and smartcare plus financial incentives group.


Options:
A: Inclusion Criteria:

* SIMS score ranks over high 20% of total

Exclusion Criteria:

* Had been prescribed with psychological problems or medical problems.
B: Inclusion Criteria:

1. male students aged between 19 to 45;
2. body mass index ≥ 27;
3. smartphone user (either Android or iPhone);
4. able and willing to attend a four pre-specified visit during the study period.

Exclusion Criteria:

1. any treatment involving pharmacotherapy, procedure, or surgery;
2. use of any activity tracker device during the last three months.
3. Those who answered positively to any Physical Activity Readiness Questionnaire (PAR-Q) question were also excluded.
C: Inclusion Criteria:

* Must be between 18-65 years old
* Own and use a smartphone and/or a tablet with a data plan
* BMI must be between 25-49.9 kg/m2
* Must be willing to reduce caloric intake and increase physical activity
* Not currently participating in a weight loss study in a weight loss study that involved podcasts

Exclusion Criteria:

* Over the age of 65 years old
* Currently participating in a weight loss program
* Has lost more than 10 pounds in the past 6 months
* Diagnosed with stroke or heart attack
* Diagnosed with diabetes that is controlled using medication
D: Inclusion Criteria:

* Self-reported African American
* Insufficiently Active ( 60 mins or less of PA per wk measured by Exercise Vital Sign Questionnaire)
* BMI\>30
* English speaking and reading
* Own non-Kindle Smartphone iOS 7 or above, or Android 2.3 or above

Exclusion Criteria:

* Concurrent participation in another physical activity, nutrition, or weight loss program
* Endorsement of an item on the Physical Activity Readiness Questionnaire (PAR-Q) unless physical note is provided
* Pregnant or plans to become pregnant in next 12 months
* Plans to relocate out of Phoenix area in next 12 months

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Dexmedetomidine Versus Propofol for Prolonged Sedation in Critically Ill Trauma and Surgical Patients
Brief Summary: The purpose of this study is to assess the efficacy of dexmedetomidine versus propofol for prolonged sedation in trauma and surgical patients.


Options:
A: Inclusion Criteria:

* all adult patients (18 years and older) admitted at the critical care unit of our hospital

Exclusion Criteria:

* admitted \< 12 hours on ICU
* not able to understand Dutch
* patients with serious hearing and visibility disabilities
* mentally retarded patients
* patients suffering from receptive aphasia
* delirious before admission
B: Inclusion Criteria:

* 18 years of age or over
* Mechanically ventilated, with anticipated need for MV ≥48 hrs
* ICU team has decided to initiate continuous sedative/analgesic infusion(s)
* informed consent from patient and/or SDM

Exclusion Criteria

* Admission after resuscitation from cardiac arrest
* Traumatic brain injury
* Currently receiving neuromuscular blocking agents
* Allergy to midazolam and lorazepam
* Lack of commitment to aggressive treatment
* Previous enrolment in SLEAP, or current enrolment in related trial
C: Inclusion Criteria:

* Patients were included in the study if they were 18 years of age or older,
* mechanically ventilated,
* placed on the institutional sedation protocol,
* expected to require sedation lasting 24 hours after randomization, and
* admitted to the TSICU and followed by the Trauma/Surgical Service.

Exclusion Criteria:

Patients were excluded for any of the following:

* 72 hours or greater since sedation protocol initiation,
* treatment per the institutional traumatic brain injury (TBI) protocol,
* concomitant continuous infusion of a neuromuscular blocking agent,
* heart rate less than 50 beats per minute,
* mean arterial pressure less than 55 mmHg despite fluid resuscitation and vasopressors, and
* use of other alpha-2 agonists within 24 hours of randomization.
D: Inclusion Criteria:

* age ≥ 18
* expected length of ICU stay of over one day

Exclusion Criteria:

* history of epilepsy, Parkinson's disease, hypokinetic rigid syndrome, dementia or alcohol withdrawal syndrome
* patients admitted to the ICU for neurological reasons (including post-resuscitation patients)
* patients treated with other anti-psychotics
* prolonged QTc-time (\>500msec) or history of serious ventricular arrhythmia (in last 12 months)
* pregnancy/breast feeding
* delirious before ICU admission
* serious auditory or visual disorders
* ICU-stay ≤1 day
* unable to understand Dutch
* severely mentally disabled
* serious receptive aphasia
* moribund and not expected to survive 2 days
* known allergy to haloperidol

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Ultrasound Guided Radial Artery Cathetrization, A Novel Technique.
Brief Summary: Comparing an novel technique ( oblique view) during ultrasound guided radial artery catheterization versus Transverse and longitudinal views


Options:
A: Inclusion Criteria:

* The patient must have given his/her informed and signed consent
* The patient must be insured or beneficiary of a health insurance plan
* The patient's health status necessitates an arterial blood sample AND his/her radial arteries are deemed unpalpable OR two previous attempts at radial arterial puncture by a nurse resulted in failure

Exclusion Criteria:

* The patient is participating in another study
* The patient is in an exclusion period determined by a previous study
* The patient is under judicial protection, or any kind of guardianship
* The patient refuses to sign the consent
* It is impossible to correctly inform the patient
* The patient is pregnant, parturient, or breastfeeding
* Arterial puncture is required on femoral, humeral or axillary arteries
* The patient is in cardiac arrest
* The patient has known circulatory problems, ischemia, local infection
* The patient has a severe bleeding or hemostasis disorder (hemophilia, hypoprothrombinemia, platelets \<50,000)
* The patient is an upper limb amputee, or his/her arm is in a cast
* The patient has known allergies to methyl or propylbenzoate, propylene glycol or chlorexhidine gluconate
B: Inclusion Criteria:

* all patients with clear indication to radial artery catheterization like hemodynamic instability or the need of frequent arterial samples

Exclusion Criteria:

* refusal, Peripheral arterial diseases
C: Inclusion Criteria:

* Age above 18 years old.
* Scheduled for selective surgery.
* Requirement of perioperative vascular puncture and catheterization.
* American standard of anesthesia level I-IV.

Exclusion Criteria:

* Contraindication to vascular puncture or catheterization.
* Occlusion or thrombosis of target vessel evaluated by ultrasound.
* Refuse or disagreement from participants.
D: Inclusion Criteria:

* The subject has signed consent
* The subject is affiliated with a social security system
* Health status necessitates an arterial blood sample for diagnostic, prognostic or therapeutic reasons

Exclusion Criteria:

* The subject is participating in another study
* The subject is in a study exclusion period determined by a previous study
* The subject is under guardianship
* The subject refuses to sign consent
* Impossible to correctly inform the patient
* The patient is pregnant, breastfeeding, or parturient
* Allergies to one or more of the following: methyl, propylbenzoate, propylene glycol, chlorhexidine gluconate
* Contraindication for an arterial puncture (at the radial artery)
* Cardio-respiratory arrest

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Ultrasound Guided Radial Artery Cathetrization, A Novel Technique.
Brief Summary: Comparing an novel technique ( oblique view) during ultrasound guided radial artery catheterization versus Transverse and longitudinal views


Options:
A: Inclusion Criteria:

* All surgical intensive care unit patients at Yale New Haven Hospital in whom the indication for arterial catheterization has been established by the attending physician will be eligible for consented randomization to either the "Palpation" or the "Ultrasound" group.

Exclusion Criteria:

* The patient or his/her surrogate declines to participate or the patient lacks a radial artery into which a catheter can be place.
B: Inclusion Criteria:

* Undergoing vessel catheterization
* Able to give written informed consent

Exclusion Criteria:

* Unable to give informed consent
* Prisoners, pregnant women, and children
C: Inclusion Criteria:

* Age 18 years and older
* Undergoing diagnostic angiography for ischemic symptoms with possible PCI, or undergoing planned urgent or elective PCI
* Has provided informed consent and agrees to participate
* Patients must be equally eligible to undergo cardiac catheterization via radial or femoral access

Exclusion Criteria:

* Primary PCI for STEMI
* Planned right heart catheterization
* Valvular heart disease requiring valve surgery within 30 days after the index procedure
* Hemodialysis access (arteriovenous fistula or graft) in the arm to be used for PCI in case of assignment to radial approach (the opposite arm may be used for radial access if a dialysis graft is present in one)
* Peripheral arterial disease prohibiting vascular access
* Presence of bilateral internal mammary artery coronary bypass grafts
* International normalized ratio ≥1.5 while treated with oral vitamin K antagonists (i.e. warfarin) Receipt of oral factor Xa or IIa inhibitors ≤24 h before procedure
* Planned staged PCI within 30 days after index procedure.
* Any planned surgeries within 30 days after index procedure
* Planned dual arterial access (for example for chronic total occlusion PCI)
* Coexisting conditions that limit life expectancy to less than 30 days
* Positive pregnancy test
D: Inclusion Criteria:

* all patients with clear indication to radial artery catheterization like hemodynamic instability or the need of frequent arterial samples

Exclusion Criteria:

* refusal, Peripheral arterial diseases

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Ultrasound Guided Radial Artery Cathetrization, A Novel Technique.
Brief Summary: Comparing an novel technique ( oblique view) during ultrasound guided radial artery catheterization versus Transverse and longitudinal views


Options:
A: Inclusion Criteria:

* The subject has signed consent
* The subject is affiliated with a social security system
* Health status necessitates an arterial blood sample for diagnostic, prognostic or therapeutic reasons

Exclusion Criteria:

* The subject is participating in another study
* The subject is in a study exclusion period determined by a previous study
* The subject is under guardianship
* The subject refuses to sign consent
* Impossible to correctly inform the patient
* The patient is pregnant, breastfeeding, or parturient
* Allergies to one or more of the following: methyl, propylbenzoate, propylene glycol, chlorhexidine gluconate
* Contraindication for an arterial puncture (at the radial artery)
* Cardio-respiratory arrest
B: Inclusion Criteria:

* Patient admitted or treated in the acute emergency department
* Indication for a arterial blood gas analysis, according to the physician responsible for the patient's hospital stay / treatment

Exclusion Criteria:

* Patient age \< 16 years
C: Inclusion Criteria:

* all patients with clear indication to radial artery catheterization like hemodynamic instability or the need of frequent arterial samples

Exclusion Criteria:

* refusal, Peripheral arterial diseases
D: Inclusion Criteria:

* Age over 18 years;
* Hospitalization in resuscitation;
* Necessity of installation of an arterial catheter
* Signed informed consent.
* Affiliation to a social security scheme

Exclusion Criteria:

* Patient under tutorship or curatorship
* Minor Patient

Answer: C