Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Multicenter, Randomized, Active-Control, Phase 3B Study to Evaluate the Cardiovascular Safety of Febuxostat and Allopurinol in Subjects With Gout and Cardiovascular Comorbidities
Brief Summary: The purpose of this study is to see whether subjects with gout who receive febuxostat or allopurinol for up to 9 years have a higher rate of serious heart and blood vessel complications (major cardiovascular events).


Options:
A: Arm Label: lesinurad 200 mg + allopurinol; Type: EXPERIMENTAL; Interventions: Drug: Lesinurad, Drug: Allopurinol | Arm Label: lesinurad 400 mg + allopurinol; Type: EXPERIMENTAL; Interventions: Drug: Lesinurad, Drug: Allopurinol | Arm Label: Placebo + allopurinol; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo, Drug: Allopurinol | Intervention Type: DRUG; Name: Lesinurad; Assigned to Arm(s): lesinurad 200 mg + allopurinol | Intervention Type: DRUG; Name: Lesinurad; Assigned to Arm(s): lesinurad 400 mg + allopurinol | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo + allopurinol | Intervention Type: DRUG; Name: Allopurinol; Assigned to Arm(s): Placebo + allopurinol, lesinurad 200 mg + allopurinol, lesinurad 400 mg + allopurinol
B: Arm Label: lesinurad 200 mg + allopurinol; Type: EXPERIMENTAL; Interventions: Drug: Lesinurad, Drug: Allopurinol | Arm Label: lesinurad 400 mg + allopurinol; Type: EXPERIMENTAL; Interventions: Drug: Lesinurad, Drug: Allopurinol | Arm Label: Placebo + allopurinol; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo, Drug: Allopurinol | Intervention Type: DRUG; Name: Lesinurad; Assigned to Arm(s): lesinurad 200 mg + allopurinol | Intervention Type: DRUG; Name: Lesinurad; Assigned to Arm(s): lesinurad 400 mg + allopurinol | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo + allopurinol | Intervention Type: DRUG; Name: Allopurinol; Assigned to Arm(s): lesinurad 200 mg + allopurinol | Intervention Type: DRUG; Name: Allopurinol; Assigned to Arm(s): lesinurad 400 mg + allopurinol | Intervention Type: DRUG; Name: Allopurinol; Assigned to Arm(s): Placebo + allopurinol
C: Arm Label: Febuxostat; Type: EXPERIMENTAL; Interventions: Drug: Febuxostat | Arm Label: Allopurinol; Type: ACTIVE_COMPARATOR; Interventions: Drug: Allopurinol | Intervention Type: DRUG; Name: Febuxostat; Assigned to Arm(s): Febuxostat | Intervention Type: DRUG; Name: Allopurinol; Assigned to Arm(s): Allopurinol
D: Arm Label: Allopurinol / Sham Comparator (Febuxostat); Type: ACTIVE_COMPARATOR; Interventions: Drug: allopurinol capsule, 100-800 mg by mouth once daily, Drug: Placebo, vehicle control (febuxostat-shaped) | Arm Label: Febuxostat / Sham Comparator (Allopurinol); Type: ACTIVE_COMPARATOR; Interventions: Drug: febuxostat tablet 40-120 mg by mouth once daily, Drug: Placebo, vehicle control (allopurinol-shaped) | Intervention Type: DRUG; Name: allopurinol capsule, 100-800 mg by mouth once daily; Assigned to Arm(s): Allopurinol / Sham Comparator (Febuxostat) | Intervention Type: DRUG; Name: febuxostat tablet 40-120 mg by mouth once daily; Assigned to Arm(s): Febuxostat / Sham Comparator (Allopurinol) | Intervention Type: DRUG; Name: Placebo, vehicle control (febuxostat-shaped); Assigned to Arm(s): Allopurinol / Sham Comparator (Febuxostat) | Intervention Type: DRUG; Name: Placebo, vehicle control (allopurinol-shaped); Assigned to Arm(s): Febuxostat / Sham Comparator (Allopurinol)

Answer: C