Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Randomised, Double-blind, Placebo-controlled, 6 Treatment, 4 Period, Incomplete Cross-over Trial to Characterise the 24-hour Lung Function Profiles of Tiotropium + Olodaterol Fixed Dose Combination (2.5/5 µg, 5/5 µg), Tiotropium (2.5 µg, 5 µg) and Olodaterol (5 µg) (Oral Inhalation, Delivered by the Respimat® Inhaler) After 6 Weeks Once Daily Treatment in Patients With Chronic Obstructive Pulmonary Disease (COPD) [VIVACITOTM]
Brief Summary: The primary objective of the trial is to determine the 24-hour FEV1-time profile of tiotropium + olodaterol FDC, administered once daily by the RESPIMAT Inhaler after 6 weeks of treatment.


Options:
A: Arm Label: GFF MDI (PT003); Type: EXPERIMENTAL; Interventions: Drug: GFF MDI (PT 003) | Arm Label: GP MDI (PT001); Type: EXPERIMENTAL; Interventions: Drug: GP MDI (PT001) | Arm Label: FF MDI (PT005); Type: EXPERIMENTAL; Interventions: Drug: FF MDI (PT005) | Arm Label: Open-label tiotropium bromide inhalation powder; Type: ACTIVE_COMPARATOR; Interventions: Drug: Open-label tiotropium bromide inhalation (Spiriva® Handihaler®) | Intervention Type: DRUG; Name: GFF MDI (PT 003); Assigned to Arm(s): GFF MDI (PT003) | Intervention Type: DRUG; Name: GP MDI (PT001); Assigned to Arm(s): GP MDI (PT001) | Intervention Type: DRUG; Name: FF MDI (PT005); Assigned to Arm(s): FF MDI (PT005) | Intervention Type: DRUG; Name: Open-label tiotropium bromide inhalation (Spiriva® Handihaler®); Assigned to Arm(s): Open-label tiotropium bromide inhalation powder
B: Arm Label: tiotropium+olodaterol low dose FDC; Type: EXPERIMENTAL; Interventions: Drug: tiotropium + olodaterol, Device: Respimat | Arm Label: tiotropium+olodaterol high dose FDC; Type: EXPERIMENTAL; Interventions: Drug: tiotropium + olodaterol, Device: Respimat | Arm Label: olodaterol; Type: ACTIVE_COMPARATOR; Interventions: Drug: olodaterol, Device: Respimat | Arm Label: tiotropium low dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: tiotropium, Device: Respimat | Arm Label: tiotropium high dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: tiotropium, Device: Respimat | Intervention Type: DRUG; Name: tiotropium + olodaterol; Assigned to Arm(s): tiotropium+olodaterol low dose FDC | Intervention Type: DRUG; Name: tiotropium; Assigned to Arm(s): tiotropium low dose | Intervention Type: DRUG; Name: olodaterol; Assigned to Arm(s): olodaterol | Intervention Type: DRUG; Name: tiotropium; Assigned to Arm(s): tiotropium high dose | Intervention Type: DRUG; Name: tiotropium + olodaterol; Assigned to Arm(s): tiotropium+olodaterol high dose FDC | Intervention Type: DEVICE; Name: Respimat; Assigned to Arm(s): olodaterol, tiotropium high dose, tiotropium low dose, tiotropium+olodaterol high dose FDC, tiotropium+olodaterol low dose FDC
C: Arm Label: FF MDI (PT005); Type: EXPERIMENTAL; Interventions: Drug: FF MDI (PT005) | Arm Label: GP MDI (PT001); Type: EXPERIMENTAL; Interventions: Drug: GP MDI (PT001) | Arm Label: GFF MDI (PT003); Type: EXPERIMENTAL; Interventions: Drug: GFF MDI (PT003) | Arm Label: Placebo MDI; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: GFF MDI (PT003); Assigned to Arm(s): GFF MDI (PT003) | Intervention Type: DRUG; Name: GP MDI (PT001); Assigned to Arm(s): GP MDI (PT001) | Intervention Type: DRUG; Name: FF MDI (PT005); Assigned to Arm(s): FF MDI (PT005) | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo MDI
D: Arm Label: tiotropium+olodaterol FDC low dose; Type: EXPERIMENTAL; Interventions: Drug: tiotropium + olodaterol, Device: Respimat | Arm Label: tiotropium+olodaterol FDC high dose; Type: EXPERIMENTAL; Interventions: Drug: tiotropium + olodaterol, Device: Respimat | Arm Label: tiotropium low dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: tiotropium, Device: Respimat | Arm Label: tiotropium high dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: tiotropium, Device: Respimat | Arm Label: olodaterol; Type: ACTIVE_COMPARATOR; Interventions: Drug: olodaterol, Device: Respimat | Arm Label: placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo, Device: Respimat | Intervention Type: DRUG; Name: tiotropium + olodaterol; Assigned to Arm(s): tiotropium+olodaterol FDC high dose | Intervention Type: DRUG; Name: tiotropium; Assigned to Arm(s): tiotropium low dose | Intervention Type: DRUG; Name: olodaterol; Assigned to Arm(s): olodaterol | Intervention Type: DRUG; Name: tiotropium; Assigned to Arm(s): tiotropium high dose | Intervention Type: DRUG; Name: tiotropium + olodaterol; Assigned to Arm(s): tiotropium+olodaterol FDC low dose | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): placebo | Intervention Type: DEVICE; Name: Respimat; Assigned to Arm(s): olodaterol, placebo, tiotropium high dose, tiotropium low dose, tiotropium+olodaterol FDC high dose, tiotropium+olodaterol FDC low dose

Answer: D