Please select the outcome measures that correspond to the clinical trial below.
Title: Open, Randomised, Parallel Group Multicentre Study to Compare the Efficacy & Safety of Flutiform® pMDI vs Fluticasone pMDI Plus Formoterol DPI in Adolescent & Adult Subjects With Mild to Moderate-severe Persistent, Reversible Asthma
Brief Summary: Flutiform® compared with the individual components Flixotide® (Fluticasone) and Foradil® (Formoterol) in adolescent and adult patients.


Options:
A: Number of Participants With Any Adverse Event (AE) or Serious Adverse Event (SAE) During the Treatment Period (From the start of study medication until Visit 11 (Week 52)/Early Withdrawal); Number of Participants With Severe Asthma Exacerbations During the Treatment Period (From the start of study medication until Visit 11 (Week 52)/Early Withdrawal); Change From Baseline in Albumin and Total Protein at Week 12, Week 28, and Week 52/Early Withdrawal (Baseline; Week 12, Week 28, and Week 52/Early Withdrawal); Change From Baseline in Alkaline Phosphatase (ALP), Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST), Creatine Kinase (CK), and Gamma Glutamyltransferase (GGT) at Week 12, Week 28, and Week 52/Early Withdrawal (Baseline; Week 12, Week 28, and Week 52/Early Withdrawal); Change From Baseline in Direct Bilirubin, Indirect Bilirubin, Total Bilirubin, and Creatinine at Week 12, Week 28, and Week 52/Early Withdrawal (Baseline; Week 12, Week 28, and Week 52/Early Withdrawal); Change From Baseline in Chloride, Carbon Dioxide Content/Bicarbonate, Glucose, Potassium, Sodium, and Urea/Blood Urea Nitrogen (BUN) at Week 12, Week 28, and Week 52/Early Withdrawal (Baseline; Week 12, Week 28, and Week 52/Early Withdrawal); Change From Baseline in the Percentage of Basophils, Eosinophils, Hematocrit, Lymphocytes, Monocytes, and Segmented Neutrophils in the Blood at Week 12, Week 28, and Week 52/Early Withdrawal (Baseline; Week 12, Week 28, and Week 52/Early Withdrawal); Change From Baseline in Eosinophil Count, Total Absolute Neutrophil Count (ANC), Platelet Count, and White Blood Cell (WBC) Count at Week 12, Week 28, and Week 52/Early Withdrawal (Baseline; Week 12, Week 28, and Week 52/Early Withdrawal); Change From Baseline in Hematocrit at Week 12, Week 28, and Week 52/Early Withdrawal (Baseline; Week 12, Week 28, and Week 52/Early Withdrawal); Change From Baseline in Hemoglobin at Week 12, Week 28, and Week 52/Early Withdrawal (Baseline; Week 12, Week 28, and Week 52/Early Withdrawal); Number of Participants With the Indicated Shift From Baseline to High, Normal or no Change, and Low Post-Baseline Values for Urinary Cortisol Excretion (Baseline; Week 12, Week 28, and Week 52/Early Withdrawal); Ratio of 24-hour Urinary Cortisol Excretion at Week 12 to Baseline (Baseline and Week 12); Ratio of 24-hour Urinary Cortisol Excretion at Week 28 to Baseline (Baseline and Week 28); Ratio of 24-hour Urinary Cortisol Excretion at Week 52 to Baseline (Baseline and Week 52); Number of Participants With Evidence of Oral Candidiasis at Any Time Post-Baseline (From Baseline until Visit 11/Early Withdrawal (52 weeks)); Maximum Change From Baseline in Systolic Blood Pressure (SBP) and Minimum Change From Baseline in Diastolic Blood Pressure (DBP) (From Baseline until Visit 11/Early Withdrawal (52 weeks)); Maximum Change From Baseline in Pulse Rate (From Baseline until Visit 11/Early Withdrawal (52 weeks)); Number of Participants With the Indicated Change From Baseline in Lens Opacities Classification System, Version III (LOCS III) Posterior Subcapsular Opacity (P) at Week 28 and Week 52 (Baseline; Week 28, and Week 52); Number of Participants With the Indicated Change From Baseline in Intraocular Pressure (IOP) at Week 28 and Week 52 (Baseline; Week 28 and Week 52); Change From Baseline in Horizontal Cup-to-disc Ratio at Week 28 and Week 52 (Baseline; Week 28 and Week 52); Number of Participants With the Indicated Change From Baseline in Lens Opacities Classification System, Version III (LOCS III) Cortical Opacity (C) at Week 28 and Week 52 (Baseline; Week 28 and Week 52); Change From Baseline in Lens Opacities Classification System, Version III (LOCS III) Nuclear Color (NC) at Week 28 and Week 52 (Baseline; Week 28 and Week 52); Change From Baseline in Lens Opacities Classification System, Version III (LOCS III) Nuclear Opalescence (NO) at Week 28 and Week 52 (Baseline; Week 28 and Week 52); Change From Baseline in the Logarithm of the Minimum Angle of Resolution (LogMAR) Visual Acuity at Week 28 and Week 52 (Baseline; Week 28 and Week 52); Maximum Change From Baseline in the QT Interval Using Bazett's Correction (QTcB) and QT Interval Using Fridericia's Correction (QTcF) (Baseline; Week 2, Week 12, Week 28, and Week 52/Early Withdrawal); Mean 24 Hour Holter Heart Rate for Participants With at Least 16 Hours of Recorded Data (0-24 hours at Screening, Day 1, Week 28, and Week 52); Maximum 24 Hour Holter Heart Rate for Participants With at Least 16 Hours of Recorded Data (0-24 hours at Screening, Day 1, Week 28, and Week 52)
B: Comparison of mean Forced Expriatory Volume in the 1st second (FEV1) values. (12 weeks)
C: Change From Baseline in Clinic Visit Trough (Pre-bronchodilator and Pre-dose) Forced Expiratory Volume in One Second (FEV1) at the End of the 24-week Treatment Period (Baseline and Week 24); Change From Baseline in Weighted Mean Serial FEV1 Over 0-24 Hours Post-dose at Week 24 (Baseline and Week 24)
D: Change From Baseline in Asthma Control Test (ACT) Total Score at Week 12 (Baseline and Week 12)

Answer: B