Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: McFlu2 COLD3 Prevention: A Randomized, Placebo-controlled, Double Blind Trial of Vitamin D and Health Advice for the Prevention of Upper Respiratory Tract Infections in McMaster University Students
Brief Summary: The specific objectives of this investigation are to assess the effectiveness of daily gargling and vitamin D supplementation as preventative measures against incident upper respiratory tract infection (URTI) in students attending McMaster University. Investigators hypothesize that

1. Vitamin D3 supplementation will decrease the incidence of symptomatic upper respiratory tract infections in university students
2. Gargling will decrease the incidence of symptomatic upper respiratory tract infections in university students.


Options:
A: Arm Label: Povidone-Iodine 0.2% (BETADINE®); Type: EXPERIMENTAL; Interventions: Drug: Gargle/Mouthwash | Arm Label: Hydrogen peroxide 1% (ActiveOxy); Type: EXPERIMENTAL; Interventions: Drug: Gargle/Mouthwash | Arm Label: Neem extract (Azadirachta indicia); Type: ACTIVE_COMPARATOR; Interventions: Drug: Gargle/Mouthwash | Arm Label: Hypertonic saline (2%NaCl); Type: ACTIVE_COMPARATOR; Interventions: Drug: Gargle/Mouthwash | Arm Label: Positive controls; Type: PLACEBO_COMPARATOR; Interventions: Drug: Gargle/Mouthwash | Intervention Type: DRUG; Name: Gargle/Mouthwash; Assigned to Arm(s): Hydrogen peroxide 1% (ActiveOxy), Hypertonic saline (2%NaCl), Neem extract (Azadirachta indicia), Positive controls, Povidone-Iodine 0.2% (BETADINE®)
B: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Device: Placebo | Arm Label: Iota-Carrageenan nasal spray; Type: EXPERIMENTAL; Interventions: Device: Iota-Carrageenan | Intervention Type: DEVICE; Name: Placebo; Assigned to Arm(s): Placebo | Intervention Type: DEVICE; Name: Iota-Carrageenan; Assigned to Arm(s): Iota-Carrageenan nasal spray
C: Arm Label: mouth rinse with antiviral; Type: ACTIVE_COMPARATOR; Interventions: Device: mouthrinse with bêta-cyclodextrin and citrox | Arm Label: mouth rinse without antiviral; Type: PLACEBO_COMPARATOR; Interventions: Device: mouthrinse without bêta-cyclodextrin and citrox | Intervention Type: DEVICE; Name: mouthrinse with bêta-cyclodextrin and citrox; Assigned to Arm(s): mouth rinse with antiviral | Intervention Type: DEVICE; Name: mouthrinse without bêta-cyclodextrin and citrox; Assigned to Arm(s): mouth rinse without antiviral
D: Arm Label: Vitamin D and gargling; Type: EXPERIMENTAL; Interventions: Dietary Supplement: cholecalciferol (vitamin D3), Behavioral: Gargling | Arm Label: Vitamin D and general health advice; Type: EXPERIMENTAL; Interventions: Dietary Supplement: cholecalciferol (vitamin D3) | Arm Label: Placebo and general health advice; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Placebo | Arm Label: Placebo and gargling; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Gargling, Dietary Supplement: Placebo | Intervention Type: DIETARY_SUPPLEMENT; Name: cholecalciferol (vitamin D3); Assigned to Arm(s): Vitamin D and gargling, Vitamin D and general health advice | Intervention Type: BEHAVIORAL; Name: Gargling; Assigned to Arm(s): Placebo and gargling, Vitamin D and gargling | Intervention Type: DIETARY_SUPPLEMENT; Name: Placebo; Assigned to Arm(s): Placebo and gargling, Placebo and general health advice

Answer: D