Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: An Intergroup Phase II Clinical Trial for Adolescents and Young Adults With Untreated Acute Lymphoblastic Leukemia (ALL)
Brief Summary: RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells.

PURPOSE: This phase II trial is studying how well combination chemotherapy works in treating young patients with newly diagnosed acute lymphoblastic leukemia.


Options:
A: Arm Label: lack of drug prophylaxis; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: HBPM 2500 UI anti Xa in one subcutaneous injection per day; Type: EXPERIMENTAL; Interventions: Drug: warfarine - low molecular heparin | Arm Label: warfarine 1mg daily; Type: EXPERIMENTAL; Interventions: Drug: warfarine - low molecular heparin | Intervention Type: DRUG; Name: warfarine - low molecular heparin; Assigned to Arm(s): HBPM 2500 UI anti Xa in one subcutaneous injection per day, warfarine 1mg daily
B: Arm Label: Treatment (chemotherapy, radiotherapy); Type: EXPERIMENTAL; Interventions: Drug: cyclophosphamide, Drug: cytarabine, Drug: daunorubicin hydrochloride, Drug: dexamethasone, Drug: doxorubicin hydrochloride, Drug: mercaptopurine, Drug: methotrexate, Drug: pegaspargase, Drug: thioguanine, Drug: vincristine sulfate, Radiation: radiation therapy | Intervention Type: DRUG; Name: cyclophosphamide; Assigned to Arm(s): Treatment (chemotherapy, radiotherapy) | Intervention Type: DRUG; Name: cytarabine; Assigned to Arm(s): Treatment (chemotherapy, radiotherapy) | Intervention Type: DRUG; Name: daunorubicin hydrochloride; Assigned to Arm(s): Treatment (chemotherapy, radiotherapy) | Intervention Type: DRUG; Name: dexamethasone; Assigned to Arm(s): Treatment (chemotherapy, radiotherapy) | Intervention Type: DRUG; Name: doxorubicin hydrochloride; Assigned to Arm(s): Treatment (chemotherapy, radiotherapy) | Intervention Type: DRUG; Name: mercaptopurine; Assigned to Arm(s): Treatment (chemotherapy, radiotherapy) | Intervention Type: DRUG; Name: methotrexate; Assigned to Arm(s): Treatment (chemotherapy, radiotherapy) | Intervention Type: DRUG; Name: pegaspargase; Assigned to Arm(s): Treatment (chemotherapy, radiotherapy) | Intervention Type: DRUG; Name: thioguanine; Assigned to Arm(s): Treatment (chemotherapy, radiotherapy) | Intervention Type: DRUG; Name: vincristine sulfate; Assigned to Arm(s): Treatment (chemotherapy, radiotherapy) | Intervention Type: RADIATION; Name: radiation therapy; Assigned to Arm(s): Treatment (chemotherapy, radiotherapy)
C: Arm Label: PEG-asparaginase 6 weeks intervals; Type: EXPERIMENTAL; Interventions: Drug: PEG Asparaginase at six weeks interval | Arm Label: PEG-Asparaginase 2 weeks intervals; Type: ACTIVE_COMPARATOR; Interventions: Drug: PEG Asparaginase at two weeks interval | Intervention Type: DRUG; Name: PEG Asparaginase at six weeks interval; Assigned to Arm(s): PEG-asparaginase 6 weeks intervals | Intervention Type: DRUG; Name: PEG Asparaginase at two weeks interval; Assigned to Arm(s): PEG-Asparaginase 2 weeks intervals
D: Arm Label: Semuloparin; Type: EXPERIMENTAL; Interventions: Drug: Semuloparin sodium | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo (for semuloparin) | Intervention Type: DRUG; Name: Semuloparin sodium; Assigned to Arm(s): Semuloparin | Intervention Type: DRUG; Name: Placebo (for semuloparin); Assigned to Arm(s): Placebo

Answer: B