TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Liraglutide Effect and Action in Diabetes (LEAD-2): Effect on Glycaemic Control After Once Daily Administration of Liraglutide in Combination With Metformin Versus Metformin Monotherapy Versus Metformin and Glimepiride Combination Therapy in Subjects With Type 2 Diabetes
Brief Summary: This trial is conducted in Europe, Oceania, Africa, Asia and South America. This trial is designed to show the effect of treatment with liraglutide when adding to existing metformin therapy and to compare it with the effects of metformin monotherapy and combination therapy of metformin and glimepiride. Two trial periods: A 6 month (26 weeks) randomised, double-blinded period followed by an 18 months open-label extension, in total 2 years (104 weeks).


Options:
A: Intervention Type: BEHAVIORAL; Name: Insulin; Assigned to Arm(s): N/A
B: Arm Label: Blood pressure; Type: PLACEBO_COMPARATOR; Interventions: Drug: Perindopril-indapamide | Arm Label: Glucose control; Type: OTHER; Interventions: Drug: Gliclazide MR-based glucose lowering | Intervention Type: DRUG; Name: Perindopril-indapamide; Assigned to Arm(s): Blood pressure | Intervention Type: DRUG; Name: Gliclazide MR-based glucose lowering; Assigned to Arm(s): Glucose control
C: Arm Label: Lira 0.6 + Met; Type: EXPERIMENTAL; Interventions: Drug: liraglutide, Drug: metformin, Drug: placebo | Arm Label: Lira 1.2 + Met; Type: EXPERIMENTAL; Interventions: Drug: metformin, Drug: placebo, Drug: liraglutide | Arm Label: Lira 1.8 + Met; Type: EXPERIMENTAL; Interventions: Drug: metformin, Drug: placebo, Drug: liraglutide | Arm Label: Met Mono; Type: ACTIVE_COMPARATOR; Interventions: Drug: metformin, Drug: placebo | Arm Label: Met + Glim; Type: ACTIVE_COMPARATOR; Interventions: Drug: metformin, Drug: glimepiride, Drug: placebo | Intervention Type: DRUG; Name: liraglutide; Assigned to Arm(s): Lira 0.6 + Met | Intervention Type: DRUG; Name: metformin; Assigned to Arm(s): Lira 0.6 + Met, Lira 1.2 + Met, Lira 1.8 + Met, Met + Glim, Met Mono | Intervention Type: DRUG; Name: glimepiride; Assigned to Arm(s): Met + Glim | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Lira 0.6 + Met, Lira 1.2 + Met, Lira 1.8 + Met, Met Mono | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Met + Glim, Met Mono | Intervention Type: DRUG; Name: liraglutide; Assigned to Arm(s): Lira 1.2 + Met | Intervention Type: DRUG; Name: liraglutide; Assigned to Arm(s): Lira 1.8 + Met
D: Arm Label: Liraglutide; Type: EXPERIMENTAL; Interventions: Drug: liraglutide | Arm Label: Exenatide; Type: ACTIVE_COMPARATOR; Interventions: Drug: exenatide | Intervention Type: DRUG; Name: liraglutide; Assigned to Arm(s): Liraglutide | Intervention Type: DRUG; Name: exenatide; Assigned to Arm(s): Exenatide

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Trial to Investigate the Efficacy and the Safety of Thrice-Daily NN2000-Mix70 (NovoRapid 70 Mix) Compared to Twice-Daily NN-X14Mix30 (NovoRapid 30 Mix) in Subjects With Type 2 Diabetes Mellitus
Brief Summary: This trial is conducted in Japan. This a clinical trial to study the efficacy and safety of three times a day BIAsp-70 compared to two times a day BIAsp-30 in subjects with type 2 diabetes.


Options:
A: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: Insulin glargine, Drug: Insulin glulisine | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Drug: Regular insulin | Intervention Type: DRUG; Name: Insulin glargine; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: Regular insulin; Assigned to Arm(s): 2 | Intervention Type: DRUG; Name: Insulin glulisine; Assigned to Arm(s): 1
B: Intervention Type: DRUG; Name: biphasic insulin aspart; Assigned to Arm(s): N/A
C: Intervention Type: DRUG; Name: human insulin; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: insulin aspart; Assigned to Arm(s): N/A
D: Intervention Type: DRUG; Name: insulin lispro; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: insulin aspart; Assigned to Arm(s): N/A

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: CRISTAL: Colloids Compared to Crystalloids in Fluid Resuscitation of Critically Ill Patients: A Multinational Randomised Controlled Trial
Brief Summary: Background: Two recent systematic reviews of the literature and meta-analyses have suggested that colloids administration might be deleterious in critically ill patients.

Objective: To compare the effects on hospital mortality of crystalloids and colloids when given for fluid resuscitation in critically ill patients.

Setting: Adult intensive care units (ICUs) in several European countries.

Study design: A multinational, randomised, controlled trial performed on two parallel groups.

Intervention: Any type of crystalloids (control group) versus any type of colloids (including albumin).

Patients: All patients above the legal age of consent and hospitalised in an intensive care unit, who need fluid resuscitation (according to the physician). Pregnant women, moribund patients, brain dead patients, and patients who have a known allergy to colloids or severe head injury or major burns (\> 20% of body surface) or dehydration will not be included.

Primary endpoint: 28-day mortality.

Hypothesis: Assuming a hospital mortality rate of 20% in the crystalloids group, a 0.05 type I error, 3010 patients are needed to show a difference between the 2 groups of 5% with a 90% probability (two-sided test).


Options:
A: Arm Label: 1, Albumin and Crystalloids; Type: OTHER; Interventions: Other: Albumin and Crystalloids | Arm Label: 2, Crystalloids; Type: OTHER; Interventions: Other: Crystalloids | Intervention Type: OTHER; Name: Albumin and Crystalloids; Assigned to Arm(s): 1, Albumin and Crystalloids | Intervention Type: OTHER; Name: Crystalloids; Assigned to Arm(s): 2, Crystalloids
B: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: 7.5% hypertonic saline/6% Dextran-70 (HSD) | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Drug: 7.5% hypertonic saline (HS) | Arm Label: 3; Type: PLACEBO_COMPARATOR; Interventions: Drug: 0.9% normal saline | Intervention Type: DRUG; Name: 7.5% hypertonic saline/6% Dextran-70 (HSD); Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: 7.5% hypertonic saline (HS); Assigned to Arm(s): 2 | Intervention Type: DRUG; Name: 0.9% normal saline; Assigned to Arm(s): 3
C: Arm Label: HES 130/0.4; Type: EXPERIMENTAL; Interventions: Drug: 6% Hydroxyethyl starch 130/0.4 | Arm Label: Ringer acetate; Type: ACTIVE_COMPARATOR; Interventions: Drug: Ringers acetate | Intervention Type: DRUG; Name: 6% Hydroxyethyl starch 130/0.4; Assigned to Arm(s): HES 130/0.4 | Intervention Type: DRUG; Name: Ringers acetate; Assigned to Arm(s): Ringer acetate
D: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Drug: Crystalloids | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Drug: Colloids | Intervention Type: DRUG; Name: Crystalloids; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: Colloids; Assigned to Arm(s): 2 | Intervention Type: DRUG; Name: Crystalloids; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: Colloids; Assigned to Arm(s): 2

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Efficacy of Concerta in Treating ADHD in Mothers of Children With ADHD
Brief Summary: This study involves a 7 week dose-response trial of Concerta™ methylphenidate for mothers of children with ADHD who have ADHD themselves. The aim of this study is to assess the efficacy of Concerta™ in improving adult ADHD symptoms and impairments (primary outcome), as well as observed and reported parenting (secondary outcome). The researchers hypothesize that Concerta™ will significantly decrease mothers ADHD symptoms and impairment, as well as improve observed and reported parenting


Options:
A: Intervention Type: DRUG; Name: Concerta; Assigned to Arm(s): N/A
B: Arm Label: Ritalin LA; Type: EXPERIMENTAL; Interventions: Drug: Ritalin LA (methylphenidate hydrochloride extended release) | Intervention Type: DRUG; Name: Ritalin LA (methylphenidate hydrochloride extended release); Assigned to Arm(s): Ritalin LA
C: Arm Label: A; Type: EXPERIMENTAL; Interventions: Drug: Methylphenidate Transdermal System (MTS) | Arm Label: B; Type: PLACEBO_COMPARATOR; Interventions: Other: placebo patch | Intervention Type: DRUG; Name: Methylphenidate Transdermal System (MTS); Assigned to Arm(s): A | Intervention Type: OTHER; Name: placebo patch; Assigned to Arm(s): B
D: Intervention Type: DRUG; Name: methylphenidate hydrochloride extended-release tablets; Assigned to Arm(s): N/A

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A New Approach to Office Hysteroscopy Compared With Traditional Hysteroscopy
Brief Summary: This randomized clinical trial compares two methods of diagnostic hysteroscopy: vaginoscopic hysteroscopy vs. traditional method. Pain intensity was estimated using a visual analogue scale (VAS), and patient satisfaction was evaluated. These endpoints were compared by treatment assignment. Vaginoscopic hysteroscopy was associated with significantly lower VAS scores, indicating reduced experience of pain in this treatment group; however, this was not associated with improved patient satisfaction.


Options:
A: Arm Label: dried biological amnion graft; Type: EXPERIMENTAL; Interventions: Procedure: dried biological amnion graft, Device: Foley balloon, Drug: estradiol valerate tablets+dydrogesterone Tablets | Arm Label: Foley catheter balloon only; Type: SHAM_COMPARATOR; Interventions: Device: Foley balloon, Drug: estradiol valerate tablets+dydrogesterone Tablets | Intervention Type: PROCEDURE; Name: dried biological amnion graft; Assigned to Arm(s): dried biological amnion graft | Intervention Type: DEVICE; Name: Foley balloon; Assigned to Arm(s): Foley catheter balloon only, dried biological amnion graft | Intervention Type: DRUG; Name: estradiol valerate tablets+dydrogesterone Tablets; Assigned to Arm(s): Foley catheter balloon only, dried biological amnion graft
B: Intervention Type: PROCEDURE; Name: vaginoscopic hysteroscopy; Assigned to Arm(s): N/A
C: Arm Label: Additional diagnostic tests; Type: EXPERIMENTAL; Interventions: Procedure: Office hysteroscopy (in combination with a 'Saline Infusion Sonography'(SIS)) | Arm Label: Routine fertility workup; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: PROCEDURE; Name: Office hysteroscopy (in combination with a 'Saline Infusion Sonography'(SIS)); Assigned to Arm(s): Additional diagnostic tests
D: Arm Label: Uterine polypectomy using morcellator; Type: EXPERIMENTAL; Interventions: Device: hysteroscopic morcellator (TruClear) | Arm Label: Electical Resection; Type: ACTIVE_COMPARATOR; Interventions: Device: Bipolar Electrical resectoscope (Versapoint) | Intervention Type: DEVICE; Name: hysteroscopic morcellator (TruClear); Assigned to Arm(s): Uterine polypectomy using morcellator | Intervention Type: DEVICE; Name: Bipolar Electrical resectoscope (Versapoint); Assigned to Arm(s): Electical Resection

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Evaluation of Function and Effect of Exercise Therapy in Patients With Osteoarthritis of the Hip. A Randomized Controlled Trial.
Brief Summary: Aims:

1. Evaluate the effect of an exercise therapy program and patient education, versus patient education only, on hip function among patients with radiologically verified hip OA
2. To identify biomechanical differences during gait, one-leg standing , and two-legged-raise analysis in patients with hip OA following either exercise therapy and patient education program, or a patient education program only.

Main Hypothesis:

Significant improved hip function (WOMAC) will be demonstrated in patients with hip osteoarthritis (OA) (radiographically verified hip OA) following a patient education program and a 12 week exercise therapy program, compared to those only going through a patient education program.

Material and Methods:

110 patients with radiographically verified hip OA will be included in the randomized controlled trial; they will be randomized into:

1. Patient Education, or
2. Patient Education in addition to a supervised exercise program.

The main outcome is:

The Disease Specific WOMAC-Index.

Secondary outcome measures are:

SF-36v2 (quality of life),PASE (activity score), Self-efficacy for pain, muscle strength tests, gait analysis (biomechanical analysis),6 minutes walking test, Åstrand's bike test, range of motion.

Status:

The PhD student is accepted at the University of Oslo,and the study has so far included 17 subjects.

The study will be carried out:

NAR-Orthopedic Centre, Ullevaal University Hospital in collaboration with Diakonhjemmet Hospital and University of Delaware.

The study is included in our research program for active rehabilitation.


Options:
A: Arm Label: yoga intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Hatha yoga | Arm Label: wait list control; Type: OTHER; Interventions: Behavioral: Hatha Yoga | Intervention Type: BEHAVIORAL; Name: Hatha yoga; Assigned to Arm(s): yoga intervention | Intervention Type: BEHAVIORAL; Name: Hatha Yoga; Assigned to Arm(s): wait list control
B: Arm Label: Patient education; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Patient education and supervised exercise | Arm Label: Patient education and supervised exercise; Type: EXPERIMENTAL; Interventions: Procedure: Patient education and supervised exercise | Intervention Type: PROCEDURE; Name: Patient education and supervised exercise; Assigned to Arm(s): Patient education, Patient education and supervised exercise
C: Arm Label: Tai Chi; Type: EXPERIMENTAL; Interventions: Behavioral: Tai Chi versus Attention Control | Arm Label: Wellness Education and Stretching; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Tai Chi versus Attention Control | Intervention Type: BEHAVIORAL; Name: Tai Chi versus Attention Control; Assigned to Arm(s): Tai Chi, Wellness Education and Stretching
D: Intervention Type: BEHAVIORAL; Name: Tai Chi classes; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: Hydrotherapy classes; Assigned to Arm(s): N/A

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized Controlled Trial of a Psychoeducational Group Program for Unipolar Depression in Adults in Norway
Brief Summary: The purpose of the study is to test the efficacy of a psychoeducational group program on unipolar depression


Options:
A: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: Escitalopram, Behavioral: Interpersonal Psychotherapy | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Drug: Escitalopram, Behavioral: Clinical Monitoring | Intervention Type: DRUG; Name: Escitalopram; Assigned to Arm(s): 1, 2 | Intervention Type: BEHAVIORAL; Name: Interpersonal Psychotherapy; Assigned to Arm(s): 1 | Intervention Type: BEHAVIORAL; Name: Clinical Monitoring; Assigned to Arm(s): 2
B: Intervention Type: BEHAVIORAL; Name: Control with depression course (CWD); Assigned to Arm(s): N/A
C: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Mindfulness Based Cognitive Therapy | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Health Enhancement Program and medication management | Intervention Type: BEHAVIORAL; Name: Mindfulness Based Cognitive Therapy; Assigned to Arm(s): 1 | Intervention Type: BEHAVIORAL; Name: Health Enhancement Program and medication management; Assigned to Arm(s): 2
D: Arm Label: Mindfulness-based Cognitive Therapy; Type: EXPERIMENTAL; Interventions: Behavioral: Mindfulness-based Cognitive Therapy, Biological: Standard psychiatric care | Arm Label: CBASP; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: The Cognitive Behavioral Analysis System of Psychotherapy, Biological: Standard psychiatric care | Arm Label: Treatment-as-usual; Type: ACTIVE_COMPARATOR; Interventions: Biological: Standard psychiatric care | Intervention Type: BEHAVIORAL; Name: Mindfulness-based Cognitive Therapy; Assigned to Arm(s): Mindfulness-based Cognitive Therapy | Intervention Type: BEHAVIORAL; Name: The Cognitive Behavioral Analysis System of Psychotherapy; Assigned to Arm(s): CBASP | Intervention Type: BIOLOGICAL; Name: Standard psychiatric care; Assigned to Arm(s): CBASP, Mindfulness-based Cognitive Therapy, Treatment-as-usual

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Computer-Based Therapy for Mild Cognitive Impairment
Brief Summary: The purpose of this study is to determine the neuropsychological and neurophysiological impacts of a computer-based training program designed to improve the cognitive performance of patients with mild cognitive impairment (MCI).


Options:
A: Arm Label: Robot intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Robot assisted cognitive training | Arm Label: Conventional intervention; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Conventional cognitive training group | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Robot assisted cognitive training; Assigned to Arm(s): Robot intervention | Intervention Type: BEHAVIORAL; Name: Conventional cognitive training group; Assigned to Arm(s): Conventional intervention
B: Arm Label: Aerobic exercise; Type: EXPERIMENTAL; Interventions: Behavioral: Group 1, Behavioral: Group 2 | Arm Label: Stretching/toning; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Group 3, Behavioral: Group 4 | Arm Label: Computer-based mental activity training; Type: EXPERIMENTAL; Interventions: Behavioral: Group 1, Behavioral: Group 3 | Arm Label: Educational DVD training; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Group 2, Behavioral: Group 4 | Intervention Type: BEHAVIORAL; Name: Group 1; Assigned to Arm(s): Aerobic exercise, Computer-based mental activity training | Intervention Type: BEHAVIORAL; Name: Group 2; Assigned to Arm(s): Aerobic exercise, Educational DVD training | Intervention Type: BEHAVIORAL; Name: Group 3; Assigned to Arm(s): Computer-based mental activity training, Stretching/toning | Intervention Type: BEHAVIORAL; Name: Group 4; Assigned to Arm(s): Educational DVD training, Stretching/toning
C: Intervention Type: PROCEDURE; Name: Computer-based training for Mild Cognitive Impairment (MCI); Assigned to Arm(s): N/A
D: Arm Label: Cognitive training group (Cog); Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Cognitive training | Arm Label: Physical exercise group (PE); Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Physical exercise | Arm Label: Sequential training group (Seq); Type: EXPERIMENTAL; Interventions: Behavioral: Cognitive training, Behavioral: Physical exercise | Arm Label: Dual-task training group (Dual); Type: EXPERIMENTAL; Interventions: Behavioral: Cognitive training, Behavioral: Physical exercise | Intervention Type: BEHAVIORAL; Name: Cognitive training; Assigned to Arm(s): Cognitive training group (Cog), Dual-task training group (Dual), Sequential training group (Seq) | Intervention Type: BEHAVIORAL; Name: Physical exercise; Assigned to Arm(s): Dual-task training group (Dual), Physical exercise group (PE), Sequential training group (Seq)

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Computer-Based Therapy for Mild Cognitive Impairment
Brief Summary: The purpose of this study is to determine the neuropsychological and neurophysiological impacts of a computer-based training program designed to improve the cognitive performance of patients with mild cognitive impairment (MCI).


Options:
A: Arm Label: Standard health counseling at baseline; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Lifestyle counseling; Type: EXPERIMENTAL; Interventions: Behavioral: Nutritional guidance, Behavioral: Exercise, Behavioral: Cognitive training, Other: Reduction of vascular risk factors | Intervention Type: BEHAVIORAL; Name: Nutritional guidance; Assigned to Arm(s): Lifestyle counseling | Intervention Type: BEHAVIORAL; Name: Exercise; Assigned to Arm(s): Lifestyle counseling | Intervention Type: BEHAVIORAL; Name: Cognitive training; Assigned to Arm(s): Lifestyle counseling | Intervention Type: OTHER; Name: Reduction of vascular risk factors; Assigned to Arm(s): Lifestyle counseling
B: Intervention Type: PROCEDURE; Name: Computer-based training for Mild Cognitive Impairment (MCI); Assigned to Arm(s): N/A
C: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: complex cognitive training | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: complex cognitive training | Intervention Type: BEHAVIORAL; Name: complex cognitive training; Assigned to Arm(s): 1, 2
D: Arm Label: Memory Training; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Cognitive Training | Arm Label: Reasoning Training; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Cognitive Training | Arm Label: Speed of Processing Training; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Cognitive Training | Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Cognitive Training | Intervention Type: BEHAVIORAL; Name: Cognitive Training; Assigned to Arm(s): Control, Memory Training, Reasoning Training, Speed of Processing Training

Answer: B