Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Phase II Trial of Response-Adapted Chemotherapy Based on Positron Emission Tomography for Non-Bulky Stage I and II Hodgkin Lymphoma
Brief Summary: This phase II trial studies how well chemotherapy based on positron emission tomography (PET) scan works in treating patients with stage I or stage II Hodgkin lymphoma. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. Radiation therapy uses high energy x-rays to kill cancer cells. Giving combination chemotherapy together with radiation therapy may kill more cancer cells and allow doctors to save the part of the body where the cancer started. Comparing results of diagnostic procedures, such as PET scan, done before, during, and after chemotherapy may help doctors predict a patient's response to treatment and help plan the best treatment.


Options:
A: Arm Label: Treatment (chemotherapy and F-18 PET/CT); Type: EXPERIMENTAL; Interventions: Biological: Bleomycin Sulfate, Drug: Doxorubicin Hydrochloride, Drug: Procarbazine Hydrochloride, Drug: Vinblastine Sulfate, Drug: Dacarbazine, Drug: Cyclophosphamide, Drug: Etoposide phosphate, Drug: prednisone, Drug: Radiation Therapy, Radiation: Fludeoxyglucose F-18, Procedure: computed tomography, Procedure: Positron Emission Tomography | Intervention Type: BIOLOGICAL; Name: Bleomycin Sulfate; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: Doxorubicin Hydrochloride; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: Procarbazine Hydrochloride; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: Vinblastine Sulfate; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: Dacarbazine; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: Cyclophosphamide; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: Etoposide phosphate; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: prednisone; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: Radiation Therapy; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: RADIATION; Name: Fludeoxyglucose F-18; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: PROCEDURE; Name: computed tomography; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: PROCEDURE; Name: Positron Emission Tomography; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT)
B: Arm Label: Arm A; Type: OTHER; Interventions: Drug: ABVD | Arm Label: Arm B; Type: OTHER; Interventions: Drug: ABVD and Radiotherapy | Intervention Type: DRUG; Name: ABVD; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: ABVD and Radiotherapy; Assigned to Arm(s): Arm B
C: Arm Label: doxorubicin + vinblastine + gemcitabine; Type: EXPERIMENTAL; Interventions: Drug: doxorubicin hydrochloride, Drug: gemcitabine hydrochloride, Drug: vinblastine, Procedure: fludeoxyglucose F 18 positron-emission tomography (PET) scan, Procedure: CT scan | Intervention Type: DRUG; Name: doxorubicin hydrochloride; Assigned to Arm(s): doxorubicin + vinblastine + gemcitabine | Intervention Type: DRUG; Name: gemcitabine hydrochloride; Assigned to Arm(s): doxorubicin + vinblastine + gemcitabine | Intervention Type: DRUG; Name: vinblastine; Assigned to Arm(s): doxorubicin + vinblastine + gemcitabine | Intervention Type: PROCEDURE; Name: fludeoxyglucose F 18 positron-emission tomography (PET) scan; Assigned to Arm(s): doxorubicin + vinblastine + gemcitabine | Intervention Type: PROCEDURE; Name: CT scan; Assigned to Arm(s): doxorubicin + vinblastine + gemcitabine
D: Arm Label: Arm I; Type: ACTIVE_COMPARATOR; Interventions: Biological: bleomycin sulfate, Drug: dacarbazine, Drug: doxorubicin hydrochloride, Drug: vinblastine sulfate | Arm Label: Arm II; Type: ACTIVE_COMPARATOR; Interventions: Drug: dacarbazine, Drug: doxorubicin hydrochloride, Drug: vinblastine sulfate | Arm Label: BEACOPP-14 chemotherapy; Type: EXPERIMENTAL; Interventions: Biological: bleomycin sulfate, Biological: filgrastim, Biological: pegfilgrastim, Drug: cyclophosphamide, Drug: doxorubicin hydrochloride, Drug: etoposide, Drug: prednisolone, Drug: procarbazine hydrochloride, Drug: vincristine sulfate | Arm Label: BEACOPP-escalated chemotherapy; Type: EXPERIMENTAL; Interventions: Biological: bleomycin sulfate, Biological: filgrastim, Biological: pegfilgrastim, Drug: cyclophosphamide, Drug: doxorubicin hydrochloride, Drug: etoposide, Drug: prednisolone, Drug: procarbazine hydrochloride, Drug: vincristine sulfate | Intervention Type: BIOLOGICAL; Name: bleomycin sulfate; Assigned to Arm(s): Arm I, BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: BIOLOGICAL; Name: filgrastim; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: BIOLOGICAL; Name: pegfilgrastim; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: cyclophosphamide; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: dacarbazine; Assigned to Arm(s): Arm I, Arm II | Intervention Type: DRUG; Name: doxorubicin hydrochloride; Assigned to Arm(s): Arm I, Arm II, BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: etoposide; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: prednisolone; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: procarbazine hydrochloride; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: vinblastine sulfate; Assigned to Arm(s): Arm I, Arm II | Intervention Type: DRUG; Name: vincristine sulfate; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy

Answer: A