Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Evaluation of Antibacterial Soap for Treatment of Lymphedema and Elephantiasis in an Area Endemic for Lymphatic Filariasis
Brief Summary: Introduction. Lymphatic filariasis is a devastating mosquito-transmitted parasitic disease that causes lymphedema or elephantiasis of the leg in 15 million persons, the majority of whom are women. In these persons, frequent bacterial infections ("acute attacks") of the legs adversely affect physical health, economic well-being, and quality of life. Prevention of bacterial infections through hygiene and skin care can result in significant improvements in lymphedema and patient well-being.

Methods. To determine the extent to which antibacterial soap can help reduce the incidence of acute bacterial infections of the lower limbs in persons with filarial lymphedema, 200 patients of the Ste. Croix Hospital lymphedema treatment clinic in Leogane, Haiti randomly assigned to receive either antibacterial (Safeguard) or placebo (Camay) soap and acute attacks monitored monthly for 12 months. Both groups received specific instructions on washing and skin care.


Options:
A: Arm Label: 1: Hygiene Education; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Intensive education on personal hygiene | Arm Label: 2: Hygiene education + mupirocin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Mupirocin ointment, Behavioral: Intensive education on personal hygiene | Arm Label: Education + mupirocin + chlorhexidine; Type: ACTIVE_COMPARATOR; Interventions: Drug: Mupirocin ointment, Genetic: Chlorhexidine showers, Behavioral: Intensive education on personal hygiene | Arm Label: 4: Education + mupirocin + bleach baths; Type: ACTIVE_COMPARATOR; Interventions: Drug: Mupirocin ointment, Procedure: Bleach baths (dilute), Behavioral: Intensive education on personal hygiene | Intervention Type: DRUG; Name: Mupirocin ointment; Assigned to Arm(s): 2: Hygiene education + mupirocin, 4: Education + mupirocin + bleach baths, Education + mupirocin + chlorhexidine | Intervention Type: GENETIC; Name: Chlorhexidine showers; Assigned to Arm(s): Education + mupirocin + chlorhexidine | Intervention Type: PROCEDURE; Name: Bleach baths (dilute); Assigned to Arm(s): 4: Education + mupirocin + bleach baths | Intervention Type: BEHAVIORAL; Name: Intensive education on personal hygiene; Assigned to Arm(s): 1: Hygiene Education, 2: Hygiene education + mupirocin, 4: Education + mupirocin + bleach baths, Education + mupirocin + chlorhexidine
B: Arm Label: 1; Type: N/A; Interventions: N/A
C: Intervention Type: DRUG; Name: antimicrobial agent in soap; Assigned to Arm(s): N/A
D: Arm Label: Single-Dose IV Oritavancin Diphosphate; Type: EXPERIMENTAL; Interventions: Drug: Single-Dose IV Oritavancin Diphosphate, Drug: Placebo | Arm Label: IV Vancomycin; Type: ACTIVE_COMPARATOR; Interventions: Drug: IV Vancomycin | Intervention Type: DRUG; Name: Single-Dose IV Oritavancin Diphosphate; Assigned to Arm(s): Single-Dose IV Oritavancin Diphosphate | Intervention Type: DRUG; Name: IV Vancomycin; Assigned to Arm(s): IV Vancomycin | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Single-Dose IV Oritavancin Diphosphate

Answer: C