Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Protocol H8 for a Prospective Controlled Trial in Clinical Stage I-II Supradiaphragmatic Hodgkin's Disease. Evaluation of Treatment Efficacy and (Long Term) Toxicity in Three Different Prognostic Subgroups [H8 Trial]
Brief Summary: RATIONALE: Radiation therapy uses high-energy x-rays to kill cancer cells. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving radiation therapy together with combination chemotherapy may kill more cancer cells. It is not yet known whether radiation therapy is more effective with or without combination chemotherapy in treating patients with Hodgkin's lymphoma.

PURPOSE: This randomized phase III trial is studying radiation therapy to see how well it works with or without combination chemotherapy in treating patients with previously untreated stage I or stage II Hodgkin's lymphoma.


Options:
A: Intervention Type: BIOLOGICAL; Name: bleomycin sulfate; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: doxorubicin hydrochloride; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: mechlorethamine hydrochloride; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: prednisone; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: procarbazine hydrochloride; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: vinblastine sulfate; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: vincristine sulfate; Assigned to Arm(s): N/A | Intervention Type: RADIATION; Name: radiation therapy; Assigned to Arm(s): N/A
B: Arm Label: Arm B; Type: EXPERIMENTAL; Interventions: Drug: Bleomycin, Drug: Etoposide, Drug: Doxorubicin, Drug: Cyclophosphamide, Drug: Vincristine, Drug: Procarbazine, Drug: Prednisone | Arm Label: Arm A; Type: ACTIVE_COMPARATOR; Interventions: Drug: Doxorubicin, Drug: Bleomycin, Drug: Vinblastine, Drug: Dacarbazine | Intervention Type: DRUG; Name: Bleomycin; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Etoposide; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Doxorubicin; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Cyclophosphamide; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Vincristine; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Procarbazine; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Prednisone; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Doxorubicin; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: Bleomycin; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: Vinblastine; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: Dacarbazine; Assigned to Arm(s): Arm A
C: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Drug: Adriamycin, Drug: Bleomycin, Drug: Vinblastine, Drug: DTIC, Radiation: radiation therapy | Arm Label: C; Type: EXPERIMENTAL; Interventions: Drug: Adriamycin, Drug: Bleomycin, Drug: Etoposide, Drug: Procarbazine, Drug: Prednisone, Drug: Vincristine, Radiation: radiation therapy | Arm Label: B; Type: EXPERIMENTAL; Interventions: Drug: Adriamycin, Drug: Bleomycin, Drug: Vinblastine, Drug: DTIC, Radiation: radiation therapy | Arm Label: D; Type: EXPERIMENTAL; Interventions: Drug: Adriamycin, Drug: Bleomycin, Drug: Etoposide, Drug: Procarbazine, Drug: Prednisone, Drug: Vincristine, Radiation: radiation therapy | Intervention Type: DRUG; Name: Adriamycin; Assigned to Arm(s): A, B, C, D | Intervention Type: DRUG; Name: Bleomycin; Assigned to Arm(s): A, B, C, D | Intervention Type: DRUG; Name: Vinblastine; Assigned to Arm(s): A, B | Intervention Type: DRUG; Name: DTIC; Assigned to Arm(s): A, B | Intervention Type: DRUG; Name: Etoposide; Assigned to Arm(s): C, D | Intervention Type: DRUG; Name: Procarbazine; Assigned to Arm(s): C, D | Intervention Type: DRUG; Name: Prednisone; Assigned to Arm(s): C, D | Intervention Type: DRUG; Name: Vincristine; Assigned to Arm(s): C, D | Intervention Type: RADIATION; Name: radiation therapy; Assigned to Arm(s): A, B, C, D
D: Arm Label: ABVD; Type: ACTIVE_COMPARATOR; Interventions: Biological: bleomycin sulfate, Drug: ABVD regimen, Drug: dacarbazine, Drug: doxorubicin hydrochloride, Drug: vinblastine sulfate | Arm Label: BEACOPP; Type: EXPERIMENTAL; Interventions: Biological: bleomycin sulfate, Biological: filgrastim, Biological: pegfilgrastim, Drug: BEACOPP regimen, Drug: cyclophosphamide, Drug: doxorubicin hydrochloride, Drug: etoposide, Drug: prednisone, Drug: procarbazine hydrochloride, Drug: vincristine sulfate | Intervention Type: BIOLOGICAL; Name: bleomycin sulfate; Assigned to Arm(s): ABVD, BEACOPP | Intervention Type: BIOLOGICAL; Name: filgrastim; Assigned to Arm(s): BEACOPP | Intervention Type: BIOLOGICAL; Name: pegfilgrastim; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: ABVD regimen; Assigned to Arm(s): ABVD | Intervention Type: DRUG; Name: BEACOPP regimen; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: cyclophosphamide; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: dacarbazine; Assigned to Arm(s): ABVD | Intervention Type: DRUG; Name: doxorubicin hydrochloride; Assigned to Arm(s): ABVD, BEACOPP | Intervention Type: DRUG; Name: etoposide; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: prednisone; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: procarbazine hydrochloride; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: vinblastine sulfate; Assigned to Arm(s): ABVD | Intervention Type: DRUG; Name: vincristine sulfate; Assigned to Arm(s): BEACOPP

Answer: A