Please select the eligibility criteria that correspond to the clinical trial below.
Title: A Multicenter, Assessor-blinded, Controlled, Randomised, Parallel Group, Superiority, Pragmatic Trial Assessing the Effectiveness of Daily SMS-reminders in Pharmaceutical Care of Older Adults With Hypertension on Improving Patients' Adherence to Blood Pressure-lowering Medication
Brief Summary: By conducting the SPPA trial we try to find out, whether personalized Short Message Service (SMS) reminders of blood pressure-lowering medication can effectively increase patients' adherence to blood pressure-lowering medication. Additionally, we also evaluate their effect on patients' systolic blood pressure control.


Options:
A: Inclusion Criteria:

* Age ≥ 55 years (from the day of the 55. birthday inclusive)
* Diagnosis of primary (essential) hypertension (I10 according to International Classification of Diseases (ICD-10))
* Filling of blood pressure-lowering prescription(s) at trial recruitment (Visit 1)
* Duration of antihypertensive drug treatment for at least 1 year without any discontinuation
* Ownership of a mobile phone for personal use with the ability to open and read SMS
* Understanding of Slovak language on native-speaker level
* Informed consent for participation in the clinical trial and personally signed Informed Consent Form

Exclusion Criteria:

Exclusion criteria assessed prior to patient enrolment (by trial pharmacists):

* Planned hospitalisation during the trial period (3 months)
* Biological impairment affecting the ability to read the SMS (e.g. loss of vision, visual field cuts, aphasia)
* Living in the same household with another trial participant
* Participation in another clinical trial

Exclusion criteria assessed after patient enrolment (by trial pharmacists and project leader):

* Hospitalisation during the trial period
* Patient informs he/she won't be able to participate in the trial
* Withdrawal of Informed Consent
B: Inclusion Criteria:

* (1) had a medical diagnosis of coronary heart disease;
* (2) aged 18 years or older;
* (3) had an antihypertensive medication regimen for 90 days or more from enrollment;
* (4) able to read messages through mobile phone;
* (5) had a mobile phone that could receive messages from WeChat and reminders from Message Express;
* (6) capable of giving his/her own consent; and
* (7) had an electronic blood pressure cuff to check blood pressures and heart rates.

Exclusion Criteria:

* was enrolled in other research studies
C: Inclusion Criteria:

* Age ≥18 years old
* History of at least one of the following arterial occlusive events:

  * acute coronary syndrome (unstable angina, acute myocardial infarction with or without ST elevation),
  * stable angina,
  * ischemic cerebrovascular disease,
  * peripheral arterial disease or
  * coronary revascularization (coronary artery bypass surgery (CABG) or percutaneous transluminal coronary angioplasty (PTCA).
* Own at least one mobile phone
* Ability to read and understand text messages (SMS)
* Intention to stay in the country of recruitment during the next 12 months

Exclusion Criteria:

* Contraindication to take all cardiovascular medications used in secondary prevention.
* Participation in another randomized clinical trial that could interfere with adherence to treatment.
D: Inclusion Criteria:

* are an acute coronary syndrome patient on the non-surgical ward who will be discharged home
* own a phone with text-messaging capabilities and have the ability to access new text messages
* have the ability to provide informed consent
* have the ability to read and understand English

Exclusion Criteria:

* have a pre-scheduled surgical procedure within the duration of the study
* if it is expected that they will not survive the duration of the study due to non-cardiovascular reasons
* are currently enrolled in another research project regarding CVDs that would interfere with the study outcomes.

Answer: A