Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Multiple Dose, Randomized, Double-blind, Placebo Controlled, Parallel Clinical Trial to Assess the Effect of Aclidinium Bromide/Formoterol Fumarate Fixed-dose Combination on Lung Hyperinflation, Exercise Capacity and Physical Activity in Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Brief Summary: The present study is planned to evaluate the effect of the aclidinium bromide/formoterol fumarate 400/12 μg FDC BID on the hyperinflation, exercise endurance and physical activity in patients with moderate to severe COPD. Additionally, the effect of the behavioural intervention on top of aclidinium bromide/formoterol fumarate 400/12 μg will be assessed both on the exercise endurance and the physical activity.


Options:
A: Arm Label: KOLwebben; Type: EXPERIMENTAL; Interventions: Behavioral: KOLwebben | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: KOLwebben; Assigned to Arm(s): KOLwebben
B: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo, Drug: Plus placebo laxative, Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine Sulfate (0, 0, 8 mg); Type: EXPERIMENTAL; Interventions: Drug: Placebo, Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Drug: Plus placebo laxative, Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (0, 8, 8 mg); Type: EXPERIMENTAL; Interventions: Drug: Placebo, Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Drug: Plus placebo laxative, Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (0, 8, 16 mg); Type: EXPERIMENTAL; Interventions: Drug: Placebo, Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Drug: Plus placebo laxative, Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (8, 8, 8 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (8, 8, 16 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (8, 16, 16 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (8, 16, 24 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (16, 16, 16 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (16, 16, 24 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (16, 24, 24 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (16, 24, 32 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Morphine Sulfate (0, 0, 8 mg), Morphine sulfate (0, 8, 16 mg), Morphine sulfate (0, 8, 8 mg), Placebo | Intervention Type: DRUG; Name: Morphine Sulfate; Assigned to Arm(s): Morphine Sulfate (0, 0, 8 mg), Morphine sulfate (0, 8, 16 mg), Morphine sulfate (0, 8, 8 mg), Morphine sulfate (16, 16, 16 mg), Morphine sulfate (16, 16, 24 mg), Morphine sulfate (16, 24, 24 mg), Morphine sulfate (16, 24, 32 mg), Morphine sulfate (8, 16, 16 mg), Morphine sulfate (8, 16, 24 mg), Morphine sulfate (8, 8, 16 mg), Morphine sulfate (8, 8, 8 mg) | Intervention Type: DRUG; Name: Plus laxative (Docusate with senna); Assigned to Arm(s): Morphine Sulfate (0, 0, 8 mg), Morphine sulfate (0, 8, 16 mg), Morphine sulfate (0, 8, 8 mg), Morphine sulfate (16, 16, 16 mg), Morphine sulfate (16, 16, 24 mg), Morphine sulfate (16, 24, 24 mg), Morphine sulfate (16, 24, 32 mg), Morphine sulfate (8, 16, 16 mg), Morphine sulfate (8, 16, 24 mg), Morphine sulfate (8, 8, 16 mg), Morphine sulfate (8, 8, 8 mg) | Intervention Type: DRUG; Name: Plus placebo laxative; Assigned to Arm(s): Morphine Sulfate (0, 0, 8 mg), Morphine sulfate (0, 8, 16 mg), Morphine sulfate (0, 8, 8 mg), Placebo | Intervention Type: DEVICE; Name: FitBit charge HR (Accelerometer); Assigned to Arm(s): Morphine Sulfate (0, 0, 8 mg), Morphine sulfate (0, 8, 16 mg), Morphine sulfate (0, 8, 8 mg), Morphine sulfate (16, 16, 16 mg), Morphine sulfate (16, 16, 24 mg), Morphine sulfate (16, 24, 24 mg), Morphine sulfate (16, 24, 32 mg), Morphine sulfate (8, 16, 16 mg), Morphine sulfate (8, 16, 24 mg), Morphine sulfate (8, 8, 16 mg), Morphine sulfate (8, 8, 8 mg), Placebo
C: Arm Label: Aclidinium Bromide/Formoterol Fumarate FDC 400/12μg; Type: EXPERIMENTAL; Interventions: Drug: Aclidinium/Formoterol | Arm Label: Placebo to Aclidinium/Formoterol; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Aclidinium/Formoterol; Assigned to Arm(s): Aclidinium Bromide/Formoterol Fumarate FDC 400/12μg | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo to Aclidinium/Formoterol
D: Arm Label: Inspiratory Muscle Training; Type: EXPERIMENTAL; Interventions: Procedure: Inspiratory Muscle Training | Arm Label: Sham IMT; Type: PLACEBO_COMPARATOR; Interventions: Procedure: Inspiratory Muscle Training | Intervention Type: PROCEDURE; Name: Inspiratory Muscle Training; Assigned to Arm(s): Inspiratory Muscle Training, Sham IMT

Answer: C