Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Effect of Adding Metoclopramide and Ondansetron to a Prophylactic Phenylephrine Infusion for the Management of Nausea and Vomiting Associated With Spinal Anesthesia for Cesarean Section
Brief Summary: The study investigates the incidence of intraoperative nausea and vomiting under spinal anesthesia using a phenylephrine infusion with and without prophylactic antiemetics.


Options:
A: Inclusion Criteria:

* Healthy (i.e., ASA I, or II) patients presenting for planned c-section at New York Methodist Hospital
* Signed informed consent

Exclusion Criteria:

* They are unable or unwilling to take part in the study
* They have a history of an allergy to any medications used including ginger
* They have had any gastrointestinal surgery on the stomach, small intestine, or gall bladder.
* They have any history of bleeding disorder, (i.e., Hemophilia A/B, ITP, etc.)
* They have a contraindication to intrathecal or epidural anesthesia. ( i.e., Arnold- Chiari malformation, etc.)
* They are unable to understand instructions or questions related to study
* ASA III or IV patients
B: Inclusion Criteria:

* Pregnant women in 28 weeks
* Women who will undergo repeated lower segment cesarean section

Exclusion Criteria:

* First cesarean section
* Placenta previa.
* Rupture uterus.
* Classical caesarean section.(upper segment cesarean section)
* Sever Preeclampsia.
* Chorioamnionitis.
* prolonged or obstructed labour.
* Fibroid.
* Polyhydramnios.
* Multiple pregnancy.
C: Inclusion Criteria:

* English speaking
* ASA Physical Status I-II
* Non-laboring women
* Single gestations ≥ 36 weeks
* Obese women (Body Mass Index 35 - 55 kg/m2)
* Non-emergent CD under spinal anesthesia

Exclusion Criteria:

* Height \< 5'0"
* Antiemetic drug use in the 24 hours prior to CD
* Allergy to phenylephrine, or any other standardized medication
* Hypertensive disease of pregnancy (i.e. mild \& severe preeclampsia)
* Chronic hypertension receiving antihypertensive treatment
* Severe Cardiac disease in pregnancy with marked functional limitations
* Patients on Monoamine Oxidase Inhibitors or Tricyclic Antidepressants
* Subject enrollment in another study involving a study medication within 30 days of CD
* Any other physical or psychiatric condition which may impair their ability to cooperate with study data collection
D: Inclusion Criteria:

* English speaking ASA I-II non-laboring women with single gestations ≥36 weeks
* Scheduled or unscheduled cesarean delivery under spinal anesthesia
* Height: 5 feet-5 feet 11 in.

Exclusion Criteria:

* Laboring women needing an emergency cesarean delivery

  * Subjects less than 18 years of age
  * Receipt of a drug with antiemetic properties in the 24 hours prior to cesarean section
  * Allergy to ondansetron, or metoclopramide
  * Severe hypertensive disease of pregnancy defined as systolic blood pressure (SBP)\>160mmHg, diastolic blood pressure (DBP)\>110mmHg requiring antihypertensive treatment or associated with significant proteinuria.
  * Severe Cardiac disease in pregnancy with marked functional limitations
  * Diabetes type I
  * Patients on Monoamine Oxidase Inhibitors or Tricyclic Antidepressants
  * Morbid obesity (body mass index (BMI)\>45)
  * Inclusion in another anesthetic study involving drug administration

Answer: D