Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Optimization of Smoking Cessation Strategies Concurrent With Treatment of Tobacco Related Malignancies
Brief Summary: The purpose of this study is to find an optimal smoking cessation strategy in patients undergoing therapy for lung and head and neck cancers at selected cancer centers in Kentucky by delivering high quality smoking cessation to all enrolled patients. This study will also examine the feasibility of routinely implementing an array of smoking cessation strategies for this patient population.


Options:
A: Arm Label: High Intensity Counseling + Long Acting NRT + PRN NRT; Type: EXPERIMENTAL; Interventions: Drug: High Intensity Counseling + Long Acting NRT + PRN NRT | Arm Label: High Intensity Counseling + bupropion + PRN NRT; Type: EXPERIMENTAL; Interventions: Drug: High Intensity Counseling + bupropion + PRN NRT | Arm Label: High Intensity Counseling + varenicline + PRN NRT; Type: EXPERIMENTAL; Interventions: Drug: High Intensity Counseling + varenicline + PRN NRT | Arm Label: High Intensity Counseling + Long Acting NRT; Type: EXPERIMENTAL; Interventions: Drug: High Intensity Counseling + Long Acting NRT | Arm Label: High Intensity Counseling + bupropion; Type: EXPERIMENTAL; Interventions: Drug: High Intensity Counseling + bupropion | Arm Label: High Intensity Counseling + varenicline; Type: EXPERIMENTAL; Interventions: Drug: High Intensity Counseling + varenicline | Arm Label: Low Intensity Counseling + Long Acting NRT + PRN NRT; Type: EXPERIMENTAL; Interventions: Drug: Low Intensity Counseling + Long Acting NRT + PRN NRT | Arm Label: Low Intensity Counseling + bupropion + PRN NRT; Type: EXPERIMENTAL; Interventions: Drug: Low Intensity Counseling + bupropion + PRN NRT | Arm Label: Low Intensity Counseling + varenicline + PRN NRT; Type: EXPERIMENTAL; Interventions: Drug: Low Intensity Counseling + varenicline + PRN NRT | Arm Label: Low Intensity Counseling + Long Acting NRT; Type: EXPERIMENTAL; Interventions: Drug: Low Intensity Counseling + Long Acting NRT | Arm Label: Low Intensity Counseling + bupropion; Type: EXPERIMENTAL; Interventions: Drug: Low Intensity Counseling + bupropion | Arm Label: Low Intensity Counseling + varenicline; Type: EXPERIMENTAL; Interventions: Drug: Low Intensity Counseling + varenicline | Intervention Type: DRUG; Name: High Intensity Counseling + Long Acting NRT + PRN NRT; Assigned to Arm(s): High Intensity Counseling + Long Acting NRT + PRN NRT | Intervention Type: DRUG; Name: High Intensity Counseling + bupropion + PRN NRT; Assigned to Arm(s): High Intensity Counseling + bupropion + PRN NRT | Intervention Type: DRUG; Name: High Intensity Counseling + varenicline + PRN NRT; Assigned to Arm(s): High Intensity Counseling + varenicline + PRN NRT | Intervention Type: DRUG; Name: High Intensity Counseling + Long Acting NRT; Assigned to Arm(s): High Intensity Counseling + Long Acting NRT | Intervention Type: DRUG; Name: High Intensity Counseling + bupropion; Assigned to Arm(s): High Intensity Counseling + bupropion | Intervention Type: DRUG; Name: High Intensity Counseling + varenicline; Assigned to Arm(s): High Intensity Counseling + varenicline | Intervention Type: DRUG; Name: Low Intensity Counseling + Long Acting NRT + PRN NRT; Assigned to Arm(s): Low Intensity Counseling + Long Acting NRT + PRN NRT | Intervention Type: DRUG; Name: Low Intensity Counseling + bupropion + PRN NRT; Assigned to Arm(s): Low Intensity Counseling + bupropion + PRN NRT | Intervention Type: DRUG; Name: Low Intensity Counseling + varenicline + PRN NRT; Assigned to Arm(s): Low Intensity Counseling + varenicline + PRN NRT | Intervention Type: DRUG; Name: Low Intensity Counseling + Long Acting NRT; Assigned to Arm(s): Low Intensity Counseling + Long Acting NRT | Intervention Type: DRUG; Name: Low Intensity Counseling + bupropion; Assigned to Arm(s): Low Intensity Counseling + bupropion | Intervention Type: DRUG; Name: Low Intensity Counseling + varenicline; Assigned to Arm(s): Low Intensity Counseling + varenicline
B: Arm Label: Varenicline; Type: EXPERIMENTAL; Interventions: Drug: Varenicline | Arm Label: Transdermal Nicotine Patch; Type: EXPERIMENTAL; Interventions: Drug: Transdermal Nicotine Patch | Intervention Type: DRUG; Name: Varenicline; Assigned to Arm(s): Varenicline | Intervention Type: DRUG; Name: Transdermal Nicotine Patch; Assigned to Arm(s): Transdermal Nicotine Patch
C: Arm Label: Bupropion (Wellbutrin-SR); Type: ACTIVE_COMPARATOR; Interventions: Drug: Bupropion-SR | Arm Label: Matching Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Intervention Type: DRUG; Name: Bupropion-SR; Assigned to Arm(s): Bupropion (Wellbutrin-SR) | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Matching Placebo
D: Arm Label: Tailored intervention; Type: EXPERIMENTAL; Interventions: Drug: Nicotine replacement therapy - Transdermal nicotine patch, Drug: Nicotine replacement therapy - Nicotine gum, Drug: Nicotine replacement therapy - Nicotine lozenge, Drug: Bupropion, Drug: Varenicline, Drug: Combination pharmacotherapy - Transdermal nicotine patch + nicotine gum, Drug: Combination pharmacotherapy - Transdermal nicotine patch + nicotine lozenge, Drug: Combination pharmacotherapy - Transdermal nicotine patch + bupropion, Behavioral: Tailored behavioral intervention, Behavioral: Alcohol use risk reduction, Behavioral: Behavioral activation for depressive symptoms, Behavioral: Behavioral management of postcessation weight gain | Arm Label: Enhanced standard of care; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine replacement therapy - Transdermal nicotine patch, Drug: Nicotine replacement therapy - Nicotine gum, Drug: Nicotine replacement therapy - Nicotine lozenge, Drug: Bupropion, Drug: Varenicline, Drug: Combination pharmacotherapy - Transdermal nicotine patch + nicotine gum, Drug: Combination pharmacotherapy - Transdermal nicotine patch + nicotine lozenge, Drug: Combination pharmacotherapy - Transdermal nicotine patch + bupropion, Behavioral: Tobacco quitline referral | Intervention Type: DRUG; Name: Nicotine replacement therapy - Transdermal nicotine patch; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: DRUG; Name: Nicotine replacement therapy - Nicotine gum; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: DRUG; Name: Nicotine replacement therapy - Nicotine lozenge; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: DRUG; Name: Bupropion; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: DRUG; Name: Varenicline; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: DRUG; Name: Combination pharmacotherapy - Transdermal nicotine patch + nicotine gum; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: DRUG; Name: Combination pharmacotherapy - Transdermal nicotine patch + nicotine lozenge; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: DRUG; Name: Combination pharmacotherapy - Transdermal nicotine patch + bupropion; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: BEHAVIORAL; Name: Tobacco quitline referral; Assigned to Arm(s): Enhanced standard of care | Intervention Type: BEHAVIORAL; Name: Tailored behavioral intervention; Assigned to Arm(s): Tailored intervention | Intervention Type: BEHAVIORAL; Name: Alcohol use risk reduction; Assigned to Arm(s): Tailored intervention | Intervention Type: BEHAVIORAL; Name: Behavioral activation for depressive symptoms; Assigned to Arm(s): Tailored intervention | Intervention Type: BEHAVIORAL; Name: Behavioral management of postcessation weight gain; Assigned to Arm(s): Tailored intervention

Answer: A