TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Pain Exposure Physical Therapy Or Conservative Therapy for Patients With Complex Regional Pain Syndrome Type I
Brief Summary: The current Dutch CBO guideline treatment of Complex Regional Pain Syndrome Type I (CRPS-1) is very disappointing with chronification, disability and subsequent high medical costs and personal suffering. A possible better treatment is intensive function-oriented physical therapy or Pain Exposure in Physical Therapy (PEPT). However, there are no adequate studies performed that demonstrate the efficacy of PEPT and therefore PEPT is lacking in the Dutch CBO CRPS-1 guidelines. Despite a lacking scientific argumentation, the PEPT approach or Macedonian therapy, is now being adopted on a large scale among physical therapists in The Netherlands. There are two level C retrospective cohort studies demonstrating a promising and clinical relevant beneficial effect on pain and function after PEPT. In response to the growing demand for scientific argumentation among doctors and physical therapists with respect to the efficacy of PEPT, we conducted a pilot study at the UMC St Radboud Nijmegen. The results of this pilot study were very promising and therefore, we decided to design a large RCT to investigate the treatment effects and costs in CRPS patients treated with PEPT compared to CRPS patients treated with usual therapy according to the Dutch CBO guidelines.


Options:
A: Arm Label: High Frequency; Type: EXPERIMENTAL; Interventions: Device: Spinal Cord Stimulator HF | Arm Label: Sham; Type: SHAM_COMPARATOR; Interventions: Device: Spinal Cord Stimulator Sham | Intervention Type: DEVICE; Name: Spinal Cord Stimulator HF; Assigned to Arm(s): High Frequency | Intervention Type: DEVICE; Name: Spinal Cord Stimulator Sham; Assigned to Arm(s): Sham
B: Arm Label: Sequence 1; Type: OTHER; Interventions: Device: High frequency spinal cord stimulation | Arm Label: Sequence 2; Type: OTHER; Interventions: Device: High frequency spinal cord stimulation | Intervention Type: DEVICE; Name: High frequency spinal cord stimulation; Assigned to Arm(s): Sequence 1, Sequence 2
C: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Arm Label: Pregabalin 300 mg/day; Type: EXPERIMENTAL; Interventions: Drug: pregabalin | Arm Label: Pregabalin 600 mg/day; Type: EXPERIMENTAL; Interventions: Drug: pregabalin | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Placebo | Intervention Type: DRUG; Name: pregabalin; Assigned to Arm(s): Pregabalin 300 mg/day | Intervention Type: DRUG; Name: pregabalin; Assigned to Arm(s): Pregabalin 600 mg/day
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Procedure: PEPT | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Procedure: CBO standard | Intervention Type: PROCEDURE; Name: PEPT; Assigned to Arm(s): 1 | Intervention Type: PROCEDURE; Name: CBO standard; Assigned to Arm(s): 2

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multi-centre, Long-term Comparative Trial of High Frequency Chest Wall Oscillation Versus Positive Expiratory Pressure Mask in the Treatment of Cystic Fibrosis
Brief Summary: This study is a preliminary study designed to determine the safety and effectiveness of HFCWO using the InCourage vest system as an airway clearance technique for the treatment of CF. The study will compare HFCWO to the most commonly used airway clearance technique in Canada, namely the Positive Expiratory Pressure technique in patients with CF over a period of one year. As this is a preliminary study, it will not be able to determine if the vest is equivelant to PEP, but will provide the information needed to plan a larger study to answer that question.


Options:
A: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Other: Positive Expiratory Pressure (PEP) | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Other: High Frequency Chest Wall Oscillation (HFCWO) using InCourage Vest System | Intervention Type: OTHER; Name: Positive Expiratory Pressure (PEP); Assigned to Arm(s): A | Intervention Type: OTHER; Name: High Frequency Chest Wall Oscillation (HFCWO) using InCourage Vest System; Assigned to Arm(s): B
B: Intervention Type: DEVICE; Name: High frequency chest wall oscillator; Assigned to Arm(s): N/A
C: Arm Label: ACTs after HTS inhalation:; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Airways clearance and Hypertonic saline inhalation | Arm Label: ACTs during HTS inhalation; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Airways clearance and Hypertonic saline inhalation | Intervention Type: PROCEDURE; Name: Airways clearance and Hypertonic saline inhalation; Assigned to Arm(s): ACTs after HTS inhalation:, ACTs during HTS inhalation
D: Arm Label: Cycling in combination with Flutter® therapy; Type: EXPERIMENTAL; Interventions: Device: Flutter® | Arm Label: Cycling without Flutter® therapy; Type: ACTIVE_COMPARATOR; Interventions: Device: No Flutter® | Intervention Type: DEVICE; Name: Flutter®; Assigned to Arm(s): Cycling in combination with Flutter® therapy | Intervention Type: DEVICE; Name: No Flutter®; Assigned to Arm(s): Cycling without Flutter® therapy

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multi-centre, Long-term Comparative Trial of High Frequency Chest Wall Oscillation Versus Positive Expiratory Pressure Mask in the Treatment of Cystic Fibrosis
Brief Summary: This study is a preliminary study designed to determine the safety and effectiveness of HFCWO using the InCourage vest system as an airway clearance technique for the treatment of CF. The study will compare HFCWO to the most commonly used airway clearance technique in Canada, namely the Positive Expiratory Pressure technique in patients with CF over a period of one year. As this is a preliminary study, it will not be able to determine if the vest is equivelant to PEP, but will provide the information needed to plan a larger study to answer that question.


Options:
A: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Other: Positive Expiratory Pressure (PEP) | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Other: High Frequency Chest Wall Oscillation (HFCWO) using InCourage Vest System | Intervention Type: OTHER; Name: Positive Expiratory Pressure (PEP); Assigned to Arm(s): A | Intervention Type: OTHER; Name: High Frequency Chest Wall Oscillation (HFCWO) using InCourage Vest System; Assigned to Arm(s): B
B: Arm Label: Placebo (pooled two times a day [BID]/three times a day [TID]); Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo two times a day (BID)/three times a day (TID) | Arm Label: AZLI (pooled two times a day [BID]/three times a day [TID]); Type: EXPERIMENTAL; Interventions: Drug: AZLI 75 mg two times a day (BID)/three times a day (TID) | Intervention Type: DRUG; Name: AZLI 75 mg two times a day (BID)/three times a day (TID); Assigned to Arm(s): AZLI (pooled two times a day [BID]/three times a day [TID]) | Intervention Type: DRUG; Name: Placebo two times a day (BID)/three times a day (TID); Assigned to Arm(s): Placebo (pooled two times a day [BID]/three times a day [TID])
C: Arm Label: HFCWO Arm; Type: EXPERIMENTAL; Interventions: Device: Airway clearance Device | Arm Label: CPT Arm; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: Airway clearance Device; Assigned to Arm(s): HFCWO Arm
D: Arm Label: ACTs after HTS inhalation:; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Airways clearance and Hypertonic saline inhalation | Arm Label: ACTs during HTS inhalation; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Airways clearance and Hypertonic saline inhalation | Intervention Type: PROCEDURE; Name: Airways clearance and Hypertonic saline inhalation; Assigned to Arm(s): ACTs after HTS inhalation:, ACTs during HTS inhalation

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multi-centre, Long-term Comparative Trial of High Frequency Chest Wall Oscillation Versus Positive Expiratory Pressure Mask in the Treatment of Cystic Fibrosis
Brief Summary: This study is a preliminary study designed to determine the safety and effectiveness of HFCWO using the InCourage vest system as an airway clearance technique for the treatment of CF. The study will compare HFCWO to the most commonly used airway clearance technique in Canada, namely the Positive Expiratory Pressure technique in patients with CF over a period of one year. As this is a preliminary study, it will not be able to determine if the vest is equivelant to PEP, but will provide the information needed to plan a larger study to answer that question.


Options:
A: Arm Label: ACTs after HTS inhalation:; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Airways clearance and Hypertonic saline inhalation | Arm Label: ACTs during HTS inhalation; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Airways clearance and Hypertonic saline inhalation | Intervention Type: PROCEDURE; Name: Airways clearance and Hypertonic saline inhalation; Assigned to Arm(s): ACTs after HTS inhalation:, ACTs during HTS inhalation
B: Intervention Type: DEVICE; Name: High frequency chest wall oscillator; Assigned to Arm(s): N/A
C: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Other: Positive Expiratory Pressure (PEP) | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Other: High Frequency Chest Wall Oscillation (HFCWO) using InCourage Vest System | Intervention Type: OTHER; Name: Positive Expiratory Pressure (PEP); Assigned to Arm(s): A | Intervention Type: OTHER; Name: High Frequency Chest Wall Oscillation (HFCWO) using InCourage Vest System; Assigned to Arm(s): B
D: Arm Label: HFCWC with higher pressure/variable frequency settings; Type: ACTIVE_COMPARATOR; Interventions: Device: HFCWC with higher pressure/variable-frequency settings, Device: HFCWC with lower pressure/mid-frequency settings | Arm Label: HFCWC with lower pressure/mid-frequency settings; Type: ACTIVE_COMPARATOR; Interventions: Device: HFCWC with higher pressure/variable-frequency settings, Device: HFCWC with lower pressure/mid-frequency settings | Intervention Type: DEVICE; Name: HFCWC with higher pressure/variable-frequency settings; Assigned to Arm(s): HFCWC with higher pressure/variable frequency settings, HFCWC with lower pressure/mid-frequency settings | Intervention Type: DEVICE; Name: HFCWC with lower pressure/mid-frequency settings; Assigned to Arm(s): HFCWC with higher pressure/variable frequency settings, HFCWC with lower pressure/mid-frequency settings

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multi-centre, Long-term Comparative Trial of High Frequency Chest Wall Oscillation Versus Positive Expiratory Pressure Mask in the Treatment of Cystic Fibrosis
Brief Summary: This study is a preliminary study designed to determine the safety and effectiveness of HFCWO using the InCourage vest system as an airway clearance technique for the treatment of CF. The study will compare HFCWO to the most commonly used airway clearance technique in Canada, namely the Positive Expiratory Pressure technique in patients with CF over a period of one year. As this is a preliminary study, it will not be able to determine if the vest is equivelant to PEP, but will provide the information needed to plan a larger study to answer that question.


Options:
A: Arm Label: Usual Airway Clearance Technique; Type: ACTIVE_COMPARATOR; Interventions: Other: Usual airway clearance | Arm Label: High Frequency Chest Wall Oscillation (HFCWO); Type: EXPERIMENTAL; Interventions: Device: High Frequency Chest Wall Oscillation (HFCWO) | Intervention Type: DEVICE; Name: High Frequency Chest Wall Oscillation (HFCWO); Assigned to Arm(s): High Frequency Chest Wall Oscillation (HFCWO) | Intervention Type: OTHER; Name: Usual airway clearance; Assigned to Arm(s): Usual Airway Clearance Technique
B: Arm Label: USUAL CARE; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: INHALATION WITH PEP DEVICE; Type: ACTIVE_COMPARATOR; Interventions: Device: INHALATION WITH PEP DEVICE (Acapella Duet) | Intervention Type: DEVICE; Name: INHALATION WITH PEP DEVICE (Acapella Duet); Assigned to Arm(s): INHALATION WITH PEP DEVICE
C: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Other: Positive Expiratory Pressure (PEP) | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Other: High Frequency Chest Wall Oscillation (HFCWO) using InCourage Vest System | Intervention Type: OTHER; Name: Positive Expiratory Pressure (PEP); Assigned to Arm(s): A | Intervention Type: OTHER; Name: High Frequency Chest Wall Oscillation (HFCWO) using InCourage Vest System; Assigned to Arm(s): B
D: Arm Label: Visit A; Type: ACTIVE_COMPARATOR; Interventions: Other: Rest period | Arm Label: Visit B; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Airway clearance session using the Active Cycle of Breathing Techniques (ACBT) | Intervention Type: PROCEDURE; Name: Airway clearance session using the Active Cycle of Breathing Techniques (ACBT); Assigned to Arm(s): Visit B | Intervention Type: OTHER; Name: Rest period; Assigned to Arm(s): Visit A

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Pilot Cluster Randomised Controlled Trial of Flooring to Reduce Injuries From Falls in Elderly Care Units
Brief Summary: In hospitals, older people can fall and hurt themselves. The investigators want to see if a new type of flooring can help stop people hurting themselves as badly, if they accidentally fall.


Options:
A: Arm Label: New Flooring; Type: EXPERIMENTAL; Interventions: Other: New flooring | Arm Label: Standard Flooring; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: New flooring; Assigned to Arm(s): New Flooring
B: Arm Label: Enhanced Physical Activity; Type: EXPERIMENTAL; Interventions: Other: Enhanced Physical Activity, Other: Usual Care | Arm Label: Usual Care; Type: ACTIVE_COMPARATOR; Interventions: Other: Usual Care, Other: Social Interaction | Intervention Type: OTHER; Name: Enhanced Physical Activity; Assigned to Arm(s): Enhanced Physical Activity | Intervention Type: OTHER; Name: Usual Care; Assigned to Arm(s): Enhanced Physical Activity, Usual Care | Intervention Type: OTHER; Name: Social Interaction; Assigned to Arm(s): Usual Care
C: Intervention Type: DRUG; Name: Olanzapine; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Quetiapine; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Risperidone; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Citalopram; Assigned to Arm(s): N/A
D: Intervention Type: DEVICE; Name: BedEx Patient Occupancy Monitoring System; Assigned to Arm(s): N/A

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Phase III Trial of Pocket PATH: A Computerized Intervention to Promote Self-Care
Brief Summary: The purpose of this randomized controlled trial is to test the efficacy of a novel intervention, Pocket PATH (Personal Assistant for Tracking Health) for promoting self-care agency, self-care behaviors, and transplant-related health.


Options:
A: Arm Label: Standard of Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Pocket PATH hand-held device; Type: EXPERIMENTAL; Interventions: Behavioral: Pocket PATH (Personal Assistant for Tracking Health) | Intervention Type: BEHAVIORAL; Name: Pocket PATH (Personal Assistant for Tracking Health); Assigned to Arm(s): Pocket PATH hand-held device
B: Arm Label: Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: TAKE IT Strategy | Intervention Type: BEHAVIORAL; Name: TAKE IT Strategy; Assigned to Arm(s): Intervention
C: Arm Label: Pilloxa Pillbox; Type: EXPERIMENTAL; Interventions: Device: Pilloxa Pillbox | Arm Label: Non active Pilloxa Pillbox; Type: SHAM_COMPARATOR; Interventions: Other: Non active Pilloxa Pillbox | Intervention Type: DEVICE; Name: Pilloxa Pillbox; Assigned to Arm(s): Pilloxa Pillbox | Intervention Type: OTHER; Name: Non active Pilloxa Pillbox; Assigned to Arm(s): Non active Pilloxa Pillbox
D: Arm Label: mHealth Group; Type: EXPERIMENTAL; Interventions: Other: Pharmacist-led medication therapy using mHealth application | Arm Label: Usual Care Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Pharmacist-led medication therapy using mHealth application; Assigned to Arm(s): mHealth Group

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Protective Effects of Delayed Cord Clamping in VLBW Infants
Brief Summary: The purpose of this study is to determine whether the intervention of delaying cord clamping for 30 to 45 seconds followed by one milking of the cord while simultaneously lowering the VLBW infants below the introitus will result in less bleeding in the brain and fewer infections while in the Neonatal Intensive Care Unit (NICU) and better motor skills at 7 months corrected age. The investigators will attempt to identify the mechanisms of effect through measurement of biologic markers.


Options:
A: Arm Label: Early cord clamping (ECC); Type: OTHER; Interventions: Procedure: Early (≤30 seconds) cord clamping | Arm Label: Delayed cord clamping (DCC); Type: OTHER; Interventions: Procedure: Delayed (≤180 seconds) cord clamping | Intervention Type: PROCEDURE; Name: Early (≤30 seconds) cord clamping; Assigned to Arm(s): Early cord clamping (ECC) | Intervention Type: PROCEDURE; Name: Delayed (≤180 seconds) cord clamping; Assigned to Arm(s): Delayed cord clamping (DCC)
B: Arm Label: Early umbilical cord clamping (control); Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Delayed umbilical cord clamping; Type: EXPERIMENTAL; Interventions: Procedure: Delayed umbilical cord clamping | Intervention Type: PROCEDURE; Name: Delayed umbilical cord clamping; Assigned to Arm(s): Delayed umbilical cord clamping
C: Arm Label: 1-Delayed Cord Clamping (DCC); Type: EXPERIMENTAL; Interventions: Procedure: delayed umbilical cord clamping | Arm Label: 2-Immediate Cord Clamping (ICC); Type: ACTIVE_COMPARATOR; Interventions: Other: Immediate cord clamping | Intervention Type: PROCEDURE; Name: delayed umbilical cord clamping; Assigned to Arm(s): 1-Delayed Cord Clamping (DCC) | Intervention Type: OTHER; Name: Immediate cord clamping; Assigned to Arm(s): 2-Immediate Cord Clamping (ICC)
D: Arm Label: Immediate cord clamping; Type: ACTIVE_COMPARATOR; Interventions: Procedure: delayed cord clamping | Arm Label: Delayed Cord Clamping; Type: EXPERIMENTAL; Interventions: Procedure: delayed cord clamping | Intervention Type: PROCEDURE; Name: delayed cord clamping; Assigned to Arm(s): Delayed Cord Clamping, Immediate cord clamping

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Reducing Injuries From Medication-Related Falls by Generating Targeted Computerized Alerts for High Risk Patients Within an Electronic Prescribing System
Brief Summary: Drug-related illness accounts for 5% to 23% of hospital admissions, and is now claimed to be the sixth leading cause of mortality. Older adults are at higher risk of adverse drug-related events, and medication-related fall injuries are the most common adverse event that could be potentially prevented. There are 1.2 million falls per year among Canadian elderly, at a cost of $2.4 billion in health care services, and substantial risk of loss of independence.

The overall purpose of this research program is to reduce medication-related fall injuries by using computerized electronic prescribing and drug management systems to identify high risk patients and provide physicians with patient-specific recommendations for modifying psychotropic medication use to reduce this risk.


Options:
A: Arm Label: A - coded unit ID; Type: EXPERIMENTAL; Interventions: Other: clinical decision support | Arm Label: B - coded unit ID; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: clinical decision support; Assigned to Arm(s): A - coded unit ID
B: Arm Label: 1; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Device: CDS for psychotropic drug management | Intervention Type: DEVICE; Name: CDS for psychotropic drug management; Assigned to Arm(s): 2
C: Intervention Type: PROCEDURE; Name: Computer-Assisted diagnostic Decision Support; Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: written diagnostic guidelines; Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: electronic therapeutic reminders; Assigned to Arm(s): N/A
D: Arm Label: computerized alert; Type: EXPERIMENTAL; Interventions: Drug: Trimethoprim/Sulfamethoxazole and Warfarin | Arm Label: 2 Current practice; Type: OTHER; Interventions: Drug: Trimethoprim/Sulfamethoxazole and Warfarin | Intervention Type: DRUG; Name: Trimethoprim/Sulfamethoxazole and Warfarin; Assigned to Arm(s): 2 Current practice, computerized alert

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Reducing Injuries From Medication-Related Falls by Generating Targeted Computerized Alerts for High Risk Patients Within an Electronic Prescribing System
Brief Summary: Drug-related illness accounts for 5% to 23% of hospital admissions, and is now claimed to be the sixth leading cause of mortality. Older adults are at higher risk of adverse drug-related events, and medication-related fall injuries are the most common adverse event that could be potentially prevented. There are 1.2 million falls per year among Canadian elderly, at a cost of $2.4 billion in health care services, and substantial risk of loss of independence.

The overall purpose of this research program is to reduce medication-related fall injuries by using computerized electronic prescribing and drug management systems to identify high risk patients and provide physicians with patient-specific recommendations for modifying psychotropic medication use to reduce this risk.


Options:
A: Intervention Type: DRUG; Name: somatropin; Assigned to Arm(s): N/A
B: Arm Label: 1; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Device: CDS for psychotropic drug management | Intervention Type: DEVICE; Name: CDS for psychotropic drug management; Assigned to Arm(s): 2
C: Arm Label: A; Type: EXPERIMENTAL; Interventions: Other: Algorithm for phenprocoumon | Arm Label: B; Type: EXPERIMENTAL; Interventions: Other: algorithm for phenprocoumon | Arm Label: C; Type: ACTIVE_COMPARATOR; Interventions: Drug: Phenprocoumon | Intervention Type: OTHER; Name: Algorithm for phenprocoumon; Assigned to Arm(s): A | Intervention Type: OTHER; Name: algorithm for phenprocoumon; Assigned to Arm(s): B | Intervention Type: DRUG; Name: Phenprocoumon; Assigned to Arm(s): C
D: Arm Label: A; Type: EXPERIMENTAL; Interventions: Drug: antipsychotic dose increase | Arm Label: TAU; Type: PLACEBO_COMPARATOR; Interventions: Other: no intervention | Intervention Type: DRUG; Name: antipsychotic dose increase; Assigned to Arm(s): A | Intervention Type: OTHER; Name: no intervention; Assigned to Arm(s): TAU

Answer: B