Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Live Birth After Fresh Embryo Transfer vs Elective Embryo Cryopreservation/Frozen Embryo Transfer in Women With Polycystic Ovary Syndrome Undergoing IVF: A Multi-center Prospective Randomized Clinical Trial
Brief Summary: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of childbearing age. However, the optimal infertility treatment for PCOS patients is still a matter of controversy. Despite producing more follicles and more oocytes than other women undergoing controlled ovarian hyperstimulation during an IVF cycle, women with PCOS have comparable or lower pregnancy rates. Additionally women with PCOS patients undergoing IVF have a higher risk of developing ovarian hyperstimulation syndrome (OHSS), which may be aggravated by pregnancy after an embryo transfer in a fresh cycle. Further women with PCOS are thought to have higher rates of later pregnancy complications including spontaneous abortion, pre-eclampsia, and preterm labor that may be related to impaired implantation in the superovulated endometrium. We propose a randomized clinical trial of elective embryo cryopreservation followed by a programmed cycle of endometrial preparation and frozen embryo transfer (FET) compared to fresh embryo transfer in women with PCOS undergoing in vitro fertilization (IVF).


Options:
A: Arm Label: freeze all embryos following PGD; Type: EXPERIMENTAL; Interventions: Procedure: elective cryopreservation of available embryos after PGD | Arm Label: elective fresh embryo transfer; Type: ACTIVE_COMPARATOR; Interventions: Procedure: PGD and elective fresh embryo transfer plus cryopreservation of supernumerary available embryos after PGD | Intervention Type: PROCEDURE; Name: elective cryopreservation of available embryos after PGD; Assigned to Arm(s): freeze all embryos following PGD | Intervention Type: PROCEDURE; Name: PGD and elective fresh embryo transfer plus cryopreservation of supernumerary available embryos after PGD; Assigned to Arm(s): elective fresh embryo transfer
B: Arm Label: fresh embryo transfer group; Type: EXPERIMENTAL; Interventions: Other: fresh embryo transfer | Arm Label: frozen-thawed embryo transfer group; Type: EXPERIMENTAL; Interventions: Other: frozen-thawed embryo transfer | Intervention Type: OTHER; Name: fresh embryo transfer; Assigned to Arm(s): fresh embryo transfer group | Intervention Type: OTHER; Name: frozen-thawed embryo transfer; Assigned to Arm(s): frozen-thawed embryo transfer group
C: Arm Label: Frozen Embryo Transfer with PGD; Type: EXPERIMENTAL; Interventions: Other: PGD | Arm Label: Fresh Embryo Transfer with PGD; Type: EXPERIMENTAL; Interventions: Other: PGD | Intervention Type: OTHER; Name: PGD; Assigned to Arm(s): Fresh Embryo Transfer with PGD, Frozen Embryo Transfer with PGD
D: Arm Label: Day 3 eSET combined with Eeva; Type: ACTIVE_COMPARATOR; Interventions: Device: Eeva™ results | Arm Label: Day 5 eSET combined with Eeva; Type: ACTIVE_COMPARATOR; Interventions: Device: Eeva™ results | Arm Label: Day 5 eSET with Traditonal Morphology; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: Eeva™ results; Assigned to Arm(s): Day 3 eSET combined with Eeva, Day 5 eSET combined with Eeva

Answer: B