Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Ridge Preservation Following Tooth Extraction Using Porcine and Bovine Xenograft Materials
Brief Summary: The study is a two-arm, parallel-design, randomized, prospective clinical trial designed to examine histologic wound healing following ridge preservation using bovine xenograft and porcine xenograft materials.This protocol involves procedures that are standard care. All materials are FDA-approved materials being used in an FDA-approved manner. The test group subjects will have extraction sockets grafted with porcine xenograft (Zcore). This test group will be compared to an active control group using bovine xenograft (Bio-Oss). The null hypothesis is that there will be no significant difference in formation of new vital bone between treatment groups (primary outcome).

Each subjects will have a non-molar tooth extracted and the socket grafted with either test or control graft material. At the time of dental implant placement 18-20 weeks after tooth extraction a small core biopsy specimen will be removed from the implant site. The core biopsy will then be evaluated for the primary histologic outcome of % vital bone formation and secondary histologic outcome of % residual graft material.


Options:
A: Arm Label: Combination 50% cortical/50% cancellous FDBA; Type: EXPERIMENTAL; Interventions: Device: 50% cortical/50% cancellous FDBA | Arm Label: 100% cortical FDBA; Type: ACTIVE_COMPARATOR; Interventions: Device: 100% cortical FDBA | Arm Label: 100% cancellous FDBA; Type: ACTIVE_COMPARATOR; Interventions: Device: 100% cancellous FDBA | Intervention Type: DEVICE; Name: 50% cortical/50% cancellous FDBA; Assigned to Arm(s): Combination 50% cortical/50% cancellous FDBA | Intervention Type: DEVICE; Name: 100% cortical FDBA; Assigned to Arm(s): 100% cortical FDBA | Intervention Type: DEVICE; Name: 100% cancellous FDBA; Assigned to Arm(s): 100% cancellous FDBA
B: Arm Label: Test: Porcine Xenograft (Zcore); Type: EXPERIMENTAL; Interventions: Device: Porcine Xenograft (Zcore) | Arm Label: Active Control: Bovine Xenograft (Bio-Oss); Type: ACTIVE_COMPARATOR; Interventions: Device: Bovine Xenograft (Bio-Oss) | Intervention Type: DEVICE; Name: Porcine Xenograft (Zcore); Assigned to Arm(s): Test: Porcine Xenograft (Zcore) | Intervention Type: DEVICE; Name: Bovine Xenograft (Bio-Oss); Assigned to Arm(s): Active Control: Bovine Xenograft (Bio-Oss)
C: Arm Label: mineralized FDBA alone; Type: ACTIVE_COMPARATOR; Interventions: Device: Mineralized freeze-dried bone allograft alone | Arm Label: Combination of mineralized and deminieralized FDBA; Type: EXPERIMENTAL; Interventions: Device: Combination of Mineralized and demineralized freeze-dried bone allograft alone | Intervention Type: DEVICE; Name: Mineralized freeze-dried bone allograft alone; Assigned to Arm(s): mineralized FDBA alone | Intervention Type: DEVICE; Name: Combination of Mineralized and demineralized freeze-dried bone allograft alone; Assigned to Arm(s): Combination of mineralized and deminieralized FDBA
D: Arm Label: Placing OSSIX-Plus in Extraction Site; Type: EXPERIMENTAL; Interventions: Device: OSSIX-Plus | Intervention Type: DEVICE; Name: OSSIX-Plus; Assigned to Arm(s): Placing OSSIX-Plus in Extraction Site

Answer: B