TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Efficacy of Low Dose Naltrexone Therapy in Children With Crohn's Disease
Brief Summary: It is hypothesized that oral naltrexone will improve inflammation of the bowel by increasing endogenous enkephalin levels in subjects with active Crohn's disease. This is especially important in children who often are suffering from nutritional deprivation which retards their growth.

The key objectives are to:

1. Evaluate the effects of low dose naltrexone in children with Crohn's Disease by using the Pediatric Crohn's Disease Activity Index (PCDAI), plasma inflammatory markers, weight, and pediatric quality of life survey.
2. To determine the safety and toxicity of low dose naltrexone in pediatric subjects with active Crohn's Disease.
3. Assess the potential mechanism by which naltrexone exerts its action by measuring plasma opioid (enkephalin and endorphin levels) and proinflammatory cytokines.


Options:
A: Arm Label: Sugar pill; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo, sugar pill | Arm Label: Naltrexone; Type: EXPERIMENTAL; Interventions: Drug: Naltrexone | Intervention Type: DRUG; Name: Naltrexone; Assigned to Arm(s): Naltrexone | Intervention Type: OTHER; Name: Placebo, sugar pill; Assigned to Arm(s): Sugar pill
B: Arm Label: Arm 1; Type: EXPERIMENTAL; Interventions: Drug: Sargramostim (Leukine) | Arm Label: Arm 2; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Sargramostim (Leukine); Assigned to Arm(s): Arm 1 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Arm 2
C: Arm Label: Intervention group; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Psychoeducational programme, Other: Standard care | Arm Label: Control group; Type: PLACEBO_COMPARATOR; Interventions: Other: Standard care | Intervention Type: BEHAVIORAL; Name: Psychoeducational programme; Assigned to Arm(s): Intervention group | Intervention Type: OTHER; Name: Standard care; Assigned to Arm(s): Control group, Intervention group
D: Arm Label: FMT infusions; Type: ACTIVE_COMPARATOR; Interventions: Biological: FMT infusions | Arm Label: Placebo arm; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo infusion | Intervention Type: BIOLOGICAL; Name: FMT infusions; Assigned to Arm(s): FMT infusions | Intervention Type: OTHER; Name: Placebo infusion; Assigned to Arm(s): Placebo arm

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Evaluation of Vaccination Reminder/Recall Systems for Adolescent Patients
Brief Summary: A study team with extensive experience in immunization delivery research will evaluate the effectiveness of vaccination reminder/recall systems for adolescent patients in five types of clinical settings including: urban pediatric, urban family medicine and rural family medicine practices, public pediatric clinics, and school-based health centers. Randomized controlled trials of reminder/recall for adolescents will be conducted at each type of site, with randomization at the level of the patient.


Options:
A: Arm Label: Reminder/recall notices for vaccines; Type: EXPERIMENTAL; Interventions: Other: Reminder/recall notices for vaccines | Arm Label: Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Reminder/recall notices for vaccines; Assigned to Arm(s): Reminder/recall notices for vaccines
B: Arm Label: mailed reminder notice; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Mailed influenza vaccination reminder notice | Arm Label: No reminder notice; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Mailed influenza vaccination reminder notice; Assigned to Arm(s): mailed reminder notice
C: Arm Label: General Adolescent Vaccine Brochure; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: General Adolescent Vaccine Brochure | Arm Label: HPV brochure, recall, reminders; Type: EXPERIMENTAL; Interventions: Behavioral: HPV brochure, recall, reminders | Intervention Type: BEHAVIORAL; Name: HPV brochure, recall, reminders; Assigned to Arm(s): HPV brochure, recall, reminders | Intervention Type: BEHAVIORAL; Name: General Adolescent Vaccine Brochure; Assigned to Arm(s): General Adolescent Vaccine Brochure
D: Arm Label: Control, standard care for HPV vaccine; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Intervention, computer reminder system; Type: EXPERIMENTAL; Interventions: Behavioral: Computer reminder system | Intervention Type: BEHAVIORAL; Name: Computer reminder system; Assigned to Arm(s): Intervention, computer reminder system

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: 3T Stroke MRT for Examining Mismatch in the CSB of the Charité Universitätsmedizin Berlin (3Tesla in 1000+)
Brief Summary: The purpose of this study is to compare clinical and economic parameters of stroke patients who have received acute MRI imaging (test group) to patients who have received routine CT imaging (control group) in the clinical setting of acute stroke.


Options:
A: Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Telemonitors and pharmacy management; Type: EXPERIMENTAL; Interventions: Other: Telemonitors and pharmacy management | Intervention Type: OTHER; Name: Telemonitors and pharmacy management; Assigned to Arm(s): Telemonitors and pharmacy management
B: N/A
C: Intervention Type: BEHAVIORAL; Name: Internet-based Dyspnea Self-Management Program; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: Face-to-face Dyspnea Self-Management Program; Assigned to Arm(s): N/A
D: Arm Label: Arm 1; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Use of PDA + support to reduce weight and pain | Arm Label: Arm 2; Type: EXPERIMENTAL; Interventions: Behavioral: MOVE! level 2 group weight loss counseling | Intervention Type: BEHAVIORAL; Name: Use of PDA + support to reduce weight and pain; Assigned to Arm(s): Arm 1 | Intervention Type: BEHAVIORAL; Name: MOVE! level 2 group weight loss counseling; Assigned to Arm(s): Arm 2

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: The aim of the current work was to evaluate, for the first time in a prospective randomized study, the effect of HBOT on patients with chronic neurological deficiency due to stroke.


Options:
A: Arm Label: Treatment- HBOT; Type: EXPERIMENTAL; Interventions: Procedure: Hyperbaric Oxygen Therapy (HBOT) | Arm Label: control-HBOT; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: PROCEDURE; Name: Hyperbaric Oxygen Therapy (HBOT); Assigned to Arm(s): Treatment- HBOT
B: Intervention Type: DRUG; Name: Hyperbaric Oxygen Therapy; Assigned to Arm(s): N/A
C: Intervention Type: PROCEDURE; Name: Hyperbaric Therapy; Assigned to Arm(s): N/A
D: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Other: Hyperbaric Oxygen Treatment (HBOT) | Intervention Type: OTHER; Name: Hyperbaric Oxygen Treatment (HBOT); Assigned to Arm(s): 1

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Phase 1 Study of Integration of Early Child Development Interventions in a Community Health Service in Sindh, Pakistan
Brief Summary: The purpose of this study is to evaluate whether the integration of an early child 'stimulation and care for development' intervention, either alone or in combination with an 'enhanced care for nutrition' intervention, delivered by Lady Health Workers to families with infants and young children aged 0-24 months living in rural Sindh in Pakistan, has beneficial outcomes on child development (cognitive, language, motor and social emotional development) and child growth.


Options:
A: Arm Label: Meat; Type: ACTIVE_COMPARATOR; Interventions: Other: Meat | Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Other: Cereal | Arm Label: Fortified rice cereal; Type: ACTIVE_COMPARATOR; Interventions: Other: fortified rice cereal | Intervention Type: OTHER; Name: Meat; Assigned to Arm(s): Meat | Intervention Type: OTHER; Name: Cereal; Assigned to Arm(s): Control | Intervention Type: OTHER; Name: fortified rice cereal; Assigned to Arm(s): Fortified rice cereal
B: Arm Label: Essential Health Care (EHC) only; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Mass media | Arm Label: EHC + Micronutrient Powders; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Micronutrient powders, Behavioral: Mass media | Arm Label: EHC + BCC; Type: EXPERIMENTAL; Interventions: Behavioral: EHC + BCC, Behavioral: Mass media | Arm Label: EHC + BCC + Micronutrient powders; Type: EXPERIMENTAL; Interventions: Behavioral: EHC + BCC, Dietary Supplement: Micronutrient powders, Behavioral: Mass media | Intervention Type: BEHAVIORAL; Name: EHC + BCC; Assigned to Arm(s): EHC + BCC, EHC + BCC + Micronutrient powders | Intervention Type: DIETARY_SUPPLEMENT; Name: Micronutrient powders; Assigned to Arm(s): EHC + BCC + Micronutrient powders, EHC + Micronutrient Powders | Intervention Type: BEHAVIORAL; Name: Mass media; Assigned to Arm(s): EHC + BCC, EHC + BCC + Micronutrient powders, EHC + Micronutrient Powders, Essential Health Care (EHC) only
C: Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Control | Arm Label: ECD Group; Type: EXPERIMENTAL; Interventions: Behavioral: ECD | Arm Label: Enhanced Nutrition; Type: EXPERIMENTAL; Interventions: Behavioral: Enhanced Nutrition | Arm Label: ECD and Enhanced Nutrition; Type: EXPERIMENTAL; Interventions: Behavioral: ECD, Behavioral: Enhanced Nutrition | Intervention Type: BEHAVIORAL; Name: Control; Assigned to Arm(s): Control | Intervention Type: BEHAVIORAL; Name: ECD; Assigned to Arm(s): ECD Group, ECD and Enhanced Nutrition | Intervention Type: BEHAVIORAL; Name: Enhanced Nutrition; Assigned to Arm(s): ECD and Enhanced Nutrition, Enhanced Nutrition
D: Intervention Type: BEHAVIORAL; Name: Maternal nutrition and infant feeding advice; Assigned to Arm(s): N/A

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Phase 1 Study of Integration of Early Child Development Interventions in a Community Health Service in Sindh, Pakistan
Brief Summary: The purpose of this study is to evaluate whether the integration of an early child 'stimulation and care for development' intervention, either alone or in combination with an 'enhanced care for nutrition' intervention, delivered by Lady Health Workers to families with infants and young children aged 0-24 months living in rural Sindh in Pakistan, has beneficial outcomes on child development (cognitive, language, motor and social emotional development) and child growth.


Options:
A: Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Dietary Advice | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Dietary Advice; Assigned to Arm(s): Intervention
B: Arm Label: Doula; Type: EXPERIMENTAL; Interventions: Behavioral: Doula | Arm Label: Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Doula; Assigned to Arm(s): Doula
C: Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Control | Arm Label: ECD Group; Type: EXPERIMENTAL; Interventions: Behavioral: ECD | Arm Label: Enhanced Nutrition; Type: EXPERIMENTAL; Interventions: Behavioral: Enhanced Nutrition | Arm Label: ECD and Enhanced Nutrition; Type: EXPERIMENTAL; Interventions: Behavioral: ECD, Behavioral: Enhanced Nutrition | Intervention Type: BEHAVIORAL; Name: Control; Assigned to Arm(s): Control | Intervention Type: BEHAVIORAL; Name: ECD; Assigned to Arm(s): ECD Group, ECD and Enhanced Nutrition | Intervention Type: BEHAVIORAL; Name: Enhanced Nutrition; Assigned to Arm(s): ECD and Enhanced Nutrition, Enhanced Nutrition
D: Arm Label: Program participation; Type: EXPERIMENTAL; Interventions: Other: Enhanced-Homestead Food Production Program | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Enhanced-Homestead Food Production Program; Assigned to Arm(s): Program participation

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Efficacy and Safety of a Hospital Walking Program for Older Adults
Brief Summary: Low mobility, defined as being limited to bed or chair, is common during acute hospitalization. This study will evaluate the impact and safety of a hospital walking program for older patients during acute general medical hospitalization. Participants who are 65 years of age or older, will be randomized to usual care (UC) or to a hospital walking program (WP), which includes twice daily walks with assistance, provision of necessary ambulatory devices, and a behavioral intervention strategy designed to encourage out of bed activity. Throughout hospitalization, the WP and UC veterans will were wireless monitors on the thigh and ankle that measure activity. The primary goal will be in increase the length of time veterans spend out of bed and to assure this out of bed activity is safe.


Options:
A: Arm Label: Resistance training and protein; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Protein, Other: Resistance training, Dietary Supplement: Vitamin D | Arm Label: Resistance training and placebo; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Placebo, Other: Resistance training, Dietary Supplement: Vitamin D | Intervention Type: DIETARY_SUPPLEMENT; Name: Protein; Assigned to Arm(s): Resistance training and protein | Intervention Type: DIETARY_SUPPLEMENT; Name: Placebo; Assigned to Arm(s): Resistance training and placebo | Intervention Type: OTHER; Name: Resistance training; Assigned to Arm(s): Resistance training and placebo, Resistance training and protein | Intervention Type: DIETARY_SUPPLEMENT; Name: Vitamin D; Assigned to Arm(s): Resistance training and placebo, Resistance training and protein
B: Arm Label: Usual Care Group; Type: PLACEBO_COMPARATOR; Interventions: Other: Usual Care | Arm Label: Intervention Group; Type: EXPERIMENTAL; Interventions: Behavioral: Promoting independence in self-care | Intervention Type: BEHAVIORAL; Name: Promoting independence in self-care; Assigned to Arm(s): Intervention Group | Intervention Type: OTHER; Name: Usual Care; Assigned to Arm(s): Usual Care Group
C: Arm Label: Mobility Group; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Behavioral intervention, Other: Walking Intervention | Arm Label: Control Group; Type: PLACEBO_COMPARATOR; Interventions: Other: Friendly visits | Intervention Type: BEHAVIORAL; Name: Behavioral intervention; Assigned to Arm(s): Mobility Group | Intervention Type: OTHER; Name: Walking Intervention; Assigned to Arm(s): Mobility Group | Intervention Type: OTHER; Name: Friendly visits; Assigned to Arm(s): Control Group
D: Arm Label: Intensive physical therapy; Type: EXPERIMENTAL; Interventions: Procedure: intensive physical therapy | Arm Label: control group; Type: ACTIVE_COMPARATOR; Interventions: Procedure: control group | Intervention Type: PROCEDURE; Name: intensive physical therapy; Assigned to Arm(s): Intensive physical therapy | Intervention Type: PROCEDURE; Name: control group; Assigned to Arm(s): control group

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: An International Randomised Controlled Trial to Establish the Effects of Early Intensive Blood Pressure Lowering in Patients With Intracerebral Haemorrhage.
Brief Summary: The purpose of this academic lead study is to determine if a treatment strategy of early intensive blood pressure (BP) lowering compared to conservative BP lowering policy in patients with elevated blood pressure within 6 hours of acute intracerebral haemorrhage (ICH) improves the outcome of death and disability at 3 months after onset.


Options:
A: Intervention Type: DRUG; Name: Labetalol Hydrochloride; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Metoprolol tartrate; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Hydralazine Hydrochloride; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Glycerol Trinitrate; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Phentolamine mesylate; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Nicardipine; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Urapidil; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Esmolol; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Clonidine; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Enalaprilat; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Nitroprusside; Assigned to Arm(s): N/A
B: Arm Label: Standard SBP Reduction Arm; Type: ACTIVE_COMPARATOR; Interventions: Drug: Intravenous nicardipine hydrochloride | Arm Label: Intensive SBP Reduction Arm; Type: ACTIVE_COMPARATOR; Interventions: Drug: Intravenous nicardipine hydrochloride | Intervention Type: DRUG; Name: Intravenous nicardipine hydrochloride; Assigned to Arm(s): Intensive SBP Reduction Arm, Standard SBP Reduction Arm
C: Arm Label: Clazosentan; Type: EXPERIMENTAL; Interventions: Drug: Clazosentan | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Clazosentan; Assigned to Arm(s): Clazosentan | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
D: Arm Label: Intensive BP lowering; Type: OTHER; Interventions: Other: Blood pressure management policies | Arm Label: Guideline recommended BP lowering; Type: OTHER; Interventions: Other: Blood pressure management policies | Intervention Type: OTHER; Name: Blood pressure management policies; Assigned to Arm(s): Guideline recommended BP lowering, Intensive BP lowering

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effect of the Level of Dietary Protein on Infant Growth and Body Composition in the First Year of Life
Brief Summary: The purpose of this study is to determine whether infants fed a formula with protein levels different than a standard infant formula have similar growth and development.


Options:
A: Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Other: Standard infant formula | Arm Label: Test Product; Type: EXPERIMENTAL; Interventions: Other: Infant formula with different level of proteins | Arm Label: Breast Milk; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Standard infant formula; Assigned to Arm(s): Control | Intervention Type: OTHER; Name: Infant formula with different level of proteins; Assigned to Arm(s): Test Product
B: Arm Label: Experimental formula; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Young-child formula with low protein content | Arm Label: Control formula; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Young-child formula with protein content similar to that of cow's milk | Intervention Type: DIETARY_SUPPLEMENT; Name: Young-child formula with low protein content; Assigned to Arm(s): Experimental formula | Intervention Type: DIETARY_SUPPLEMENT; Name: Young-child formula with protein content similar to that of cow's milk; Assigned to Arm(s): Control formula
C: Arm Label: Human Milk; Type: ACTIVE_COMPARATOR; Interventions: Other: Human Milk | Arm Label: Milk based standard infant formula; Type: ACTIVE_COMPARATOR; Interventions: Other: Milk based standard infant formula | Arm Label: Milk based investigational infant formula; Type: EXPERIMENTAL; Interventions: Other: Investigational infant formula | Intervention Type: OTHER; Name: Human Milk; Assigned to Arm(s): Human Milk | Intervention Type: OTHER; Name: Investigational infant formula; Assigned to Arm(s): Milk based investigational infant formula | Intervention Type: OTHER; Name: Milk based standard infant formula; Assigned to Arm(s): Milk based standard infant formula
D: Arm Label: Study Formula (SF); Type: EXPERIMENTAL; Interventions: Other: Study Formula (SF) | Arm Label: Comparator Formula (CF); Type: ACTIVE_COMPARATOR; Interventions: Other: Comparator Formula (CF) | Arm Label: Human Milk Reference Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Study Formula (SF); Assigned to Arm(s): Study Formula (SF) | Intervention Type: OTHER; Name: Comparator Formula (CF); Assigned to Arm(s): Comparator Formula (CF)

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multicenter, Randomized, Double-blind, Placebo- and Active-controlled Study of Safety and Efficacy of Two Dosages of Epicutaneously Applied Diractin® (Ketoprofen in Transfersome® Gel) for the Treatment of Osteoarthritis of the Knee
Brief Summary: The purpose of this study is to provide replicated evidence of safety and efficacy of 50 mg and 100 mg ketoprofen in Diractin®.


Options:
A: Intervention Type: DRUG; Name: Diclofenac Topical Sodium Gel 1%; Assigned to Arm(s): N/A
B: Arm Label: Ibuprofen; Type: EXPERIMENTAL; Interventions: Drug: Ibuprofen | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Intervention Type: DRUG; Name: Ibuprofen; Assigned to Arm(s): Ibuprofen | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Placebo
C: Intervention Type: DRUG; Name: Diclofenac topical sodium gel 1%; Assigned to Arm(s): N/A
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: ketoprofen in Diractin® | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Drug: ketoprofen in Diractin® | Arm Label: 3; Type: ACTIVE_COMPARATOR; Interventions: Drug: celecoxib | Arm Label: 4; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: ketoprofen in Diractin®; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: ketoprofen in Diractin®; Assigned to Arm(s): 2 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): 4 | Intervention Type: DRUG; Name: celecoxib; Assigned to Arm(s): 3

Answer: D