Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Topical Ruxolitinib Evaluation in Atopic Dermatitis Study 2 (TRuE AD2) - A Phase 3, Double-Blind, Randomized, 8-Week, Vehicle-Controlled Efficacy and Safety Study of Ruxolitinib Cream Followed by a Long-Term Safety Extension Period in Adolescents and Adults With Atopic Dermatitis
Brief Summary: The purpose of this study is to assess the efficacy of ruxolitinib cream in adolescents and adults with atopic dermatitis (AD).


Options:
A: Arm Label: Vehicle Control (VC) Period: Vehicle Cream BID; Type: PLACEBO_COMPARATOR; Interventions: Drug: Vehicle cream | Arm Label: VC Period: Ruxolitinib 0.75% Cream BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib cream | Arm Label: VC Period: Ruxolitinib 1.5% Cream BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib cream | Arm Label: Long-Term Safety (LTS) Period: Vehicle Cream to Ruxolitinib 0.75% Cream BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib cream | Arm Label: LTS Period: Vehicle Cream to Ruxolitinib 1.5% Cream BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib cream | Arm Label: LTS Period: Ruxolitinib 0.75% Cream BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib cream | Arm Label: LTS Period: Ruxolitinib 1.5% Cream BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib cream | Intervention Type: DRUG; Name: Ruxolitinib cream; Assigned to Arm(s): LTS Period: Ruxolitinib 0.75% Cream BID, LTS Period: Ruxolitinib 1.5% Cream BID, LTS Period: Vehicle Cream to Ruxolitinib 1.5% Cream BID, Long-Term Safety (LTS) Period: Vehicle Cream to Ruxolitinib 0.75% Cream BID, VC Period: Ruxolitinib 0.75% Cream BID, VC Period: Ruxolitinib 1.5% Cream BID | Intervention Type: DRUG; Name: Vehicle cream; Assigned to Arm(s): Vehicle Control (VC) Period: Vehicle Cream BID
B: Arm Label: Double Blind (DB): Vehicle BID; Type: PLACEBO_COMPARATOR; Interventions: Drug: Vehicle Cream BID | Arm Label: DB: Triamcinolone (TAC) 0.1% BID/Vehicle Cream BID; Type: ACTIVE_COMPARATOR; Interventions: Drug: Triamcinolone 0.1% Cream BID, Drug: Vehicle Cream BID | Arm Label: DB: Ruxolitinib 0.15% Once Daily (QD); Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 0.15% Cream QD | Arm Label: DB: Ruxolitinib 0.5% QD; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 0.5% Cream QD | Arm Label: DB: Ruxolitinib 1.5% QD; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 1.5% Cream QD | Arm Label: DB: Ruxolitinib 1.5% BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 1.5% Cream BID | Arm Label: Open-Label (OL): Vehicle BID to Ruxolitinib 1.5% BID; Type: PLACEBO_COMPARATOR; Interventions: Drug: Ruxolitinib 1.5% Cream BID | Arm Label: OL: TAC BID/Vehicle BID to Ruxolitinib 1.5% BID; Type: ACTIVE_COMPARATOR; Interventions: Drug: Ruxolitinib 1.5% Cream BID | Arm Label: OL: Ruxolitinib 0.15% QD to Ruxolitinib 1.5% BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 1.5% Cream BID | Arm Label: OL: Ruxolitinib 0.5% QD to Ruxolitinib 1.5% BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 1.5% Cream BID | Arm Label: OL: Ruxolitinib 1.5% QD to Ruxolitinib 1.5% BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 1.5% Cream BID | Arm Label: OL: Ruxolitinib 1.5% BID to Ruxolitinib 1.5% BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 1.5% Cream BID | Intervention Type: DRUG; Name: Ruxolitinib 0.15% Cream QD; Assigned to Arm(s): DB: Ruxolitinib 0.15% Once Daily (QD) | Intervention Type: DRUG; Name: Ruxolitinib 0.5% Cream QD; Assigned to Arm(s): DB: Ruxolitinib 0.5% QD | Intervention Type: DRUG; Name: Ruxolitinib 1.5% Cream QD; Assigned to Arm(s): DB: Ruxolitinib 1.5% QD | Intervention Type: DRUG; Name: Ruxolitinib 1.5% Cream BID; Assigned to Arm(s): DB: Ruxolitinib 1.5% BID, OL: Ruxolitinib 0.15% QD to Ruxolitinib 1.5% BID, OL: Ruxolitinib 0.5% QD to Ruxolitinib 1.5% BID, OL: Ruxolitinib 1.5% BID to Ruxolitinib 1.5% BID, OL: Ruxolitinib 1.5% QD to Ruxolitinib 1.5% BID, OL: TAC BID/Vehicle BID to Ruxolitinib 1.5% BID, Open-Label (OL): Vehicle BID to Ruxolitinib 1.5% BID | Intervention Type: DRUG; Name: Triamcinolone 0.1% Cream BID; Assigned to Arm(s): DB: Triamcinolone (TAC) 0.1% BID/Vehicle Cream BID | Intervention Type: DRUG; Name: Vehicle Cream BID; Assigned to Arm(s): DB: Triamcinolone (TAC) 0.1% BID/Vehicle Cream BID, Double Blind (DB): Vehicle BID
C: Arm Label: AN2728 Topical Ointment, 2%; Type: EXPERIMENTAL; Interventions: Drug: AN2728 Topical Ointment, 2% | Arm Label: Matching vehicle control; Type: PLACEBO_COMPARATOR; Interventions: Drug: Matching vehicle control | Intervention Type: DRUG; Name: AN2728 Topical Ointment, 2%; Assigned to Arm(s): AN2728 Topical Ointment, 2% | Intervention Type: DRUG; Name: Matching vehicle control; Assigned to Arm(s): Matching vehicle control
D: Arm Label: Prevalent case of atopic dermatitis; Type: N/A; Interventions: Other: No intervention | Arm Label: Controls; Type: N/A; Interventions: Other: No intervention | Intervention Type: OTHER; Name: No intervention; Assigned to Arm(s): Controls, Prevalent case of atopic dermatitis

Answer: A