TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Nonpharmacologic Management of Challenging Behaviors in Veterans With Dementia
Brief Summary: The Tailored Activity Program - Veterans Administration is a Phase III efficacy trial designed to reduce behavioral symptoms in Veterans with dementia living with their caregivers in the community. The study uses a randomized two group parallel design with 160 diverse Veterans and caregivers. The experimental group receives a transformative patient-centric intervention designed to reduce the burden of behavioral symptoms in Veterans with dementia. An occupational therapist conducts an assessment to identify a Veteran's preserved capabilities, deficit areas, previous roles, habits, and interests to develop activities tailored to the Veteran. Family caregivers are then trained to incorporate activities into daily care. The attention-control group receives bi-monthly telephone contact where education on topics relevant to dementia is provided to caregivers. Key outcomes include reduced frequency and severity of behavioral symptoms using the 12-item Neuropsychiatric Inventory (primary endpoint), reduced caregiver burden, enhanced skill acquisition, efficacy using activities, and time spent providing care at 4 months; and long-term effects (8 months) on the Veteran's quality of life and frequency and severity of behavioral symptoms, and caregiver use of activities. The programs' impact of Veterans Administration cost is also examined. Study precision will be increased through face-to-face research team trainings with procedural manuals and review of audio-taped interviews and intervention sessions.


Options:
A: Arm Label: Tailored Activity Program; Type: EXPERIMENTAL; Interventions: Other: Tailored Activity Program | Arm Label: Attention Control; Type: ACTIVE_COMPARATOR; Interventions: Other: Attention Control | Intervention Type: OTHER; Name: Tailored Activity Program; Assigned to Arm(s): Tailored Activity Program | Intervention Type: OTHER; Name: Attention Control; Assigned to Arm(s): Attention Control
B: Intervention Type: BEHAVIORAL; Name: Home-Based Behavorial Intervention; Assigned to Arm(s): N/A
C: Arm Label: Day care for patients with dementia; Type: EXPERIMENTAL; Interventions: Behavioral: Day care for patients with dementia | Arm Label: Care as usual; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Day care for patients with dementia; Assigned to Arm(s): Day care for patients with dementia
D: Arm Label: Tailored Activity Program; Type: EXPERIMENTAL; Interventions: Behavioral: Tailored Activity Program | Arm Label: Home Safety and Education Program; Type: ACTIVE_COMPARATOR; Interventions: Other: Home Safety and Education Program | Intervention Type: BEHAVIORAL; Name: Tailored Activity Program; Assigned to Arm(s): Tailored Activity Program | Intervention Type: OTHER; Name: Home Safety and Education Program; Assigned to Arm(s): Home Safety and Education Program

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Evaluating the Effectiveness of an In-home Self-management Intervention to Prevent Psychological Distress in Frail Older People Living in the Community
Brief Summary: The main objectives of this study are:

1. an effect evaluation of an in-home multicomponent cognitive behavioural program on concerns about falling and related avoidance of activity (primary outcomes), as well as disability, fall incidents (secondary outcomes) and several additional outcomes in frail community-dwelling older people,
2. a process evaluation of the feasibility of the program, with the following main outcomes: population reached, performance according to protocol, exposure and engagement, opinion on the program of participants and facilitators, perceived benefit or achievement, and experienced barriers and potential solutions, and
3. an economical evaluation on the impact of the program on healthcare utilization and related costs.


Options:
A: Arm Label: Cognitive Behavioral Therapy (CBT); Type: EXPERIMENTAL; Interventions: Behavioral: Comprehensive, CBT-based, multi-component treatment | Arm Label: Treatment as usual (TAU); Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Treatment as usual | Intervention Type: BEHAVIORAL; Name: Comprehensive, CBT-based, multi-component treatment; Assigned to Arm(s): Cognitive Behavioral Therapy (CBT) | Intervention Type: BEHAVIORAL; Name: Treatment as usual; Assigned to Arm(s): Treatment as usual (TAU)
B: Arm Label: observational; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Exercise group; Type: EXPERIMENTAL; Interventions: Other: Exercise intervention | Intervention Type: OTHER; Name: Exercise intervention; Assigned to Arm(s): Exercise group
C: Arm Label: Fall prevention standard of care; Type: OTHER; Interventions: Other: Evidence-based tailored fall prevention | Arm Label: Control; Type: OTHER; Interventions: Other: Usual care | Intervention Type: OTHER; Name: Evidence-based tailored fall prevention; Assigned to Arm(s): Fall prevention standard of care | Intervention Type: OTHER; Name: Usual care; Assigned to Arm(s): Control
D: Arm Label: Cognitive behavioral program; Type: EXPERIMENTAL; Interventions: Behavioral: an in-home cognitive behavioral program | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: an in-home cognitive behavioral program; Assigned to Arm(s): Cognitive behavioral program

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Emergency Department-Based Palliative Care for Advanced Cancer Patients
Brief Summary: The purpose of this study is to: 1) identify the palliative care needs of Emergency Department patients with advanced cancer, and determine if these needs can be rapidly assessed in the ED; 2) determine whether early palliative care consultation improves survival, quality of life and other burdensome symptoms and decreases utilization as compared to usual care.


Options:
A: Arm Label: Standard oncologic care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Early Palliative Care; Type: EXPERIMENTAL; Interventions: Other: Early Palliative Care | Arm Label: Psychosocial plus early Palliative Care; Type: EXPERIMENTAL; Interventions: Behavioral: Brief Psychosocial Intervention, Other: Early Palliative Care | Intervention Type: BEHAVIORAL; Name: Brief Psychosocial Intervention; Assigned to Arm(s): Psychosocial plus early Palliative Care | Intervention Type: OTHER; Name: Early Palliative Care; Assigned to Arm(s): Early Palliative Care, Psychosocial plus early Palliative Care
B: Arm Label: ENABLE (concurrent palliative care); Type: EXPERIMENTAL; Interventions: Other: counseling intervention, Other: educational intervention, Procedure: psychosocial assessment and care, Procedure: quality-of-life assessment | Arm Label: Usual Care; Type: ACTIVE_COMPARATOR; Interventions: Other: counseling intervention, Procedure: psychosocial assessment and care, Procedure: quality-of-life assessment | Intervention Type: OTHER; Name: counseling intervention; Assigned to Arm(s): ENABLE (concurrent palliative care), Usual Care | Intervention Type: OTHER; Name: educational intervention; Assigned to Arm(s): ENABLE (concurrent palliative care) | Intervention Type: PROCEDURE; Name: psychosocial assessment and care; Assigned to Arm(s): ENABLE (concurrent palliative care), Usual Care | Intervention Type: PROCEDURE; Name: quality-of-life assessment; Assigned to Arm(s): ENABLE (concurrent palliative care), Usual Care
C: Arm Label: Early palliative care consultation; Type: EXPERIMENTAL; Interventions: Other: Early palliative care consultation | Arm Label: Care as usual; Type: OTHER; Interventions: Other: Care as usual | Intervention Type: OTHER; Name: Early palliative care consultation; Assigned to Arm(s): Early palliative care consultation | Intervention Type: OTHER; Name: Care as usual; Assigned to Arm(s): Care as usual
D: Arm Label: Standard Palliative Care Group; Type: ACTIVE_COMPARATOR; Interventions: Other: Standard Palliative Care Group | Arm Label: Integrated Palliative Care Group; Type: ACTIVE_COMPARATOR; Interventions: Other: Integrated Palliative Care Intervention | Intervention Type: OTHER; Name: Standard Palliative Care Group; Assigned to Arm(s): Standard Palliative Care Group | Intervention Type: OTHER; Name: Integrated Palliative Care Intervention; Assigned to Arm(s): Integrated Palliative Care Group

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized, Double-blind, Double-dummy, Placebo Controlled, Multicenter Study of Subcutaneous Secukinumab to Demonstrate Efficacy After Twelve Weeks of Treatment, Compared to Placebo and Etanercept, and to Assess the Safety, Tolerability and Long-term Efficacy up to One Year in Subjects With Moderate to Severe Chronic Plaque-type Psoriasis
Brief Summary: This study will assess the safety and efficacy of secukinumab compared to placebo and etanercept in patients that have moderate to severe, chronic, plaque-type psoriasis.


Options:
A: Intervention Type: DRUG; Name: etanercept; Assigned to Arm(s): N/A
B: Arm Label: Etanercept 50 mg; Type: EXPERIMENTAL; Interventions: Drug: Etanercept | Intervention Type: DRUG; Name: Etanercept; Assigned to Arm(s): Etanercept 50 mg
C: Arm Label: AIN457 150mg; Type: EXPERIMENTAL; Interventions: Drug: Placebo, Drug: secukinumab (AIN457) | Arm Label: AIN457 300mg; Type: EXPERIMENTAL; Interventions: Drug: Placebo, Drug: secukinumab (AIN457) | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: Etanercept; Type: ACTIVE_COMPARATOR; Interventions: Drug: Placebo, Drug: etanercept | Arm Label: AIN457 150mg from Placebo; Type: EXPERIMENTAL; Interventions: Drug: Placebo, Drug: secukinumab (AIN457) | Arm Label: AIN457 300mg from Placebo; Type: EXPERIMENTAL; Interventions: Drug: Placebo, Drug: secukinumab (AIN457) | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): AIN457 150mg, AIN457 150mg from Placebo, AIN457 300mg, AIN457 300mg from Placebo, Etanercept, Placebo | Intervention Type: DRUG; Name: secukinumab (AIN457); Assigned to Arm(s): AIN457 150mg, AIN457 150mg from Placebo, AIN457 300mg, AIN457 300mg from Placebo | Intervention Type: DRUG; Name: etanercept; Assigned to Arm(s): Etanercept
D: Arm Label: Placebo BID; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Arm Label: 5mg BID CP-690,550; Type: EXPERIMENTAL; Interventions: Drug: CP-690,550 | Arm Label: 10mg BID CP-690,550; Type: EXPERIMENTAL; Interventions: Drug: CP-690,550 | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Placebo BID | Intervention Type: DRUG; Name: CP-690,550; Assigned to Arm(s): 5mg BID CP-690,550 | Intervention Type: DRUG; Name: CP-690,550; Assigned to Arm(s): 10mg BID CP-690,550

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multiprofessional Impact on Body Composition, Central and Peripheric Adiposity, Lipid Profile, Hormonal Regulation, Lung, Sleep and Humor Disorders in Adolescents
Brief Summary: Obese adolescents are submitted to a multiprofessional weight loss program, which is formed by doctors, nutritionists, physiotherapists, psychologists,and physiologists. The volunteers have intervention 3 times a week during one year, where they practice exercises, have nutrition and psychology counseling, and physiotherapy orientation. Once a month they have an appointment with the doctor. The hypothesis of this study is that a multiprofessional therapy is able to improve anthropometric and biochemical parameters, and also the quality of life of obese adolescents.


Options:
A: Arm Label: control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Exercise; Type: EXPERIMENTAL; Interventions: Behavioral: exercise | Intervention Type: BEHAVIORAL; Name: exercise; Assigned to Arm(s): Exercise
B: Arm Label: Lifestyle counseling; Type: OTHER; Interventions: Other: multidisciplinary intervention | Intervention Type: OTHER; Name: multidisciplinary intervention; Assigned to Arm(s): Lifestyle counseling
C: Arm Label: Glucose; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Glucose | Arm Label: Fructose; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Fructose | Intervention Type: DIETARY_SUPPLEMENT; Name: Glucose; Assigned to Arm(s): Glucose | Intervention Type: DIETARY_SUPPLEMENT; Name: Fructose; Assigned to Arm(s): Fructose
D: Arm Label: Diet: Dietary Advice; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: General Advice | Arm Label: Low glycemic index Mediterranean Diet; Type: EXPERIMENTAL; Interventions: Behavioral: Low Glycemic Index Mediterranean Diet | Intervention Type: BEHAVIORAL; Name: Low Glycemic Index Mediterranean Diet; Assigned to Arm(s): Low glycemic index Mediterranean Diet | Intervention Type: BEHAVIORAL; Name: General Advice; Assigned to Arm(s): Diet: Dietary Advice

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Improvement of Antibiotic Prescription in Outpatient Care: a Cluster-randomised Intervention Study Using a Sentinel Surveillance Network of Physicians
Brief Summary: Antimicrobial resistance has become a world-wide problem and antibiotic consumption is a major driving force for the development of resistance. Thus optimization of antibiotic prescription and reduction of unnecessary antimicrobial treatment are essential in the prevention and reduction of antimicrobial resistance rates.

The goal of this study is the improvement of antibiotic prescription in outpatient care. The study will take place within a Swiss-wide sentinel surveillance network of physicians. The participating physicians will be randomised in a control and intervention group. The intervention group will receive therapeutic guidelines for the treatment of upper and lower respiratory tract infections and lower urinary tract infection as well as regular feed-backs on the prescription pattern of the sentinel physicians during the past months. Sentinel physicians will collect information about each antibiotic prescription, its indication and characteristics of the patient.

Our hypothesis is that the prescription pattern in the intervention group will be optimised and unnecessary antibiotic therapy will be reduced compared to the control group.


Options:
A: Arm Label: Usual information policy; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Antibiotic therapy guidelines; Type: OTHER; Interventions: Other: Mailing of antibiotic therapy guidelines to the sentinel physicians | Intervention Type: OTHER; Name: Mailing of antibiotic therapy guidelines to the sentinel physicians; Assigned to Arm(s): Antibiotic therapy guidelines
B: Arm Label: Standard of Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Other: Telehealth Pulmonary Rehabilitation | Intervention Type: OTHER; Name: Telehealth Pulmonary Rehabilitation; Assigned to Arm(s): Intervention
C: Arm Label: Integration; Type: EXPERIMENTAL; Interventions: Other: Integration | Arm Label: Co-Location; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Integration; Assigned to Arm(s): Integration
D: Arm Label: Usual Care; Type: ACTIVE_COMPARATOR; Interventions: Other: Usual Care | Arm Label: Community Paramedicine; Type: EXPERIMENTAL; Interventions: Other: Community Paramedicine | Intervention Type: OTHER; Name: Community Paramedicine; Assigned to Arm(s): Community Paramedicine | Intervention Type: OTHER; Name: Usual Care; Assigned to Arm(s): Usual Care

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: "Spot Sign" Selection of Intracerebral Hemorrhage to Guide Hemostatic Therapy: SPOTLIGHT
Brief Summary: This clinical trial will enroll 110 patients from approximately 15 Canadian stroke centres. Patients coming to the emergency department with bleeding in the brain not due to trauma or other known causes who can be treated within 6 hours of onset will undergo CT angiography using standard CT scanners ("CAT scan"). Those with a "spot sign", a type of marker on the CT scan that shows the brain is still bleeding, will be randomly assigned to a single injection of "factor 7"(a blood clotting drug used in hemophilia) or placebo (inactive saline); patients without a spot sign will not be treated. The researchers will look at how much bleeding happens after the treatments are administered, as well as clinical outcomes such as death and disability. The researchers think that factor 7 will cause the bleeding to stop faster and possibly decrease death and disability.


Options:
A: Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Drug: Desmopressin Injection | Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Drug: Normal saline | Intervention Type: DRUG; Name: Desmopressin Injection; Assigned to Arm(s): Intervention | Intervention Type: DRUG; Name: Normal saline; Assigned to Arm(s): Control
B: Arm Label: Niastase RT; Type: ACTIVE_COMPARATOR; Interventions: Biological: rfVIIa | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Standard saline solution | Intervention Type: BIOLOGICAL; Name: rfVIIa; Assigned to Arm(s): Niastase RT | Intervention Type: OTHER; Name: Standard saline solution; Assigned to Arm(s): Placebo
C: Arm Label: Tranexamic acid; Type: EXPERIMENTAL; Interventions: Drug: Tranexamic acid | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Saline 0.9% | Intervention Type: DRUG; Name: Tranexamic acid; Assigned to Arm(s): Tranexamic acid | Intervention Type: DRUG; Name: Saline 0.9%; Assigned to Arm(s): Placebo
D: Arm Label: Group 1-Recombinant activated factor VII; Type: ACTIVE_COMPARATOR; Interventions: Drug: recombinant activated factor VII | Arm Label: Group 2 - Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Arm Label: Group 3 - Observation Only Arm; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: recombinant activated factor VII; Assigned to Arm(s): Group 1-Recombinant activated factor VII | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Group 2 - Placebo

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Post Admission Cognitive Therapy (PACT) for the Inpatient Treatment of Military Personnel With Suicidal Behaviors: A Multi-Site Randomized Controlled Trial
Brief Summary: This study will implement and empirically evaluate the efficacy of a cognitive behavioral intervention program, titled, Post Admission Cognitive Therapy(PACT), for military service members and beneficiaries \[with Veterans expected to be added\] admitted for inpatient care due to severe suicide ideation and/or a recent suicide attempt.


Options:
A: Arm Label: Escitalopram; Type: ACTIVE_COMPARATOR; Interventions: Drug: Escitalopram | Arm Label: Duloxetine; Type: ACTIVE_COMPARATOR; Interventions: Drug: Duloxetine | Arm Label: CBT; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Cognitive behavioral therapy (CBT) | Intervention Type: DRUG; Name: Escitalopram; Assigned to Arm(s): Escitalopram | Intervention Type: DRUG; Name: Duloxetine; Assigned to Arm(s): Duloxetine | Intervention Type: BEHAVIORAL; Name: Cognitive behavioral therapy (CBT); Assigned to Arm(s): CBT
B: Arm Label: Psychoeducational intervention (PEI); Type: EXPERIMENTAL; Interventions: Behavioral: Psychoeducational intervention (PEI) | Arm Label: Enhanced Treatment as Usual; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Enhanced treatment as usual (ETAU) | Intervention Type: BEHAVIORAL; Name: Psychoeducational intervention (PEI); Assigned to Arm(s): Psychoeducational intervention (PEI) | Intervention Type: BEHAVIORAL; Name: Enhanced treatment as usual (ETAU); Assigned to Arm(s): Enhanced Treatment as Usual
C: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Cognitive Behavioural Therapy, Other: Treatment as usual | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Other: Treatment as usual | Intervention Type: BEHAVIORAL; Name: Cognitive Behavioural Therapy; Assigned to Arm(s): 1 | Intervention Type: OTHER; Name: Treatment as usual; Assigned to Arm(s): 1, 2
D: Arm Label: Post Admission Cognitive Therapy (PACT); Type: EXPERIMENTAL; Interventions: Behavioral: Post Admission Cognitive Therapy (PACT) | Arm Label: Enhanced Usual Care (EUC); Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Post Admission Cognitive Therapy (PACT); Assigned to Arm(s): Post Admission Cognitive Therapy (PACT)

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Post Admission Cognitive Therapy (PACT) for the Inpatient Treatment of Military Personnel With Suicidal Behaviors: A Multi-Site Randomized Controlled Trial
Brief Summary: This study will implement and empirically evaluate the efficacy of a cognitive behavioral intervention program, titled, Post Admission Cognitive Therapy(PACT), for military service members and beneficiaries \[with Veterans expected to be added\] admitted for inpatient care due to severe suicide ideation and/or a recent suicide attempt.


Options:
A: Arm Label: Post Admission Cognitive Therapy (PACT); Type: EXPERIMENTAL; Interventions: Behavioral: Post Admission Cognitive Therapy (PACT) | Arm Label: Enhanced Usual Care (EUC); Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Post Admission Cognitive Therapy (PACT); Assigned to Arm(s): Post Admission Cognitive Therapy (PACT)
B: Arm Label: Diaclectical Behavioral Therapy; Type: EXPERIMENTAL; Interventions: Behavioral: Behavioral Therapy | Arm Label: Support Therapy; Type: EXPERIMENTAL; Interventions: Behavioral: Behavioral Therapy | Arm Label: Controls; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Behavioral Therapy; Assigned to Arm(s): Diaclectical Behavioral Therapy, Support Therapy
C: Arm Label: Positive Psychology; Type: EXPERIMENTAL; Interventions: Behavioral: Positive Psychology | Arm Label: Organizational Skills; Type: SHAM_COMPARATOR; Interventions: Behavioral: Control Condition | Intervention Type: BEHAVIORAL; Name: Positive Psychology; Assigned to Arm(s): Positive Psychology | Intervention Type: BEHAVIORAL; Name: Control Condition; Assigned to Arm(s): Organizational Skills
D: Arm Label: Commitment; Type: EXPERIMENTAL; Interventions: Behavioral: DBT Skills Training | Arm Label: Psychoeducation; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: DBT Skills Training | Intervention Type: BEHAVIORAL; Name: DBT Skills Training; Assigned to Arm(s): Commitment, Psychoeducation

Answer: A