Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Alternate Chemotherapy Regimens for the Clearance of W.Bancrofti Infection: Double Blind Randomised Clinical Trial (RCT) to Study the Efficacy of Different Co-administration and Sequential Administration
Brief Summary: Diethylcarbamazine (DEC) essentially a micro-filaricidal drug is given for 12 days as standard treatment for the clearance of W. bancrofti infection. It takes about one year for the individuals to completely clear the microfilaria from the blood. It takes another two to four years to clear the antigen. The aim of the present study is to shorten the time taken for clearing the Mf and antigen from the blood either by co-administration or sequential administration of a macrofilaricidal drug, Albendazole or doxycycline. This study is a randomized, double blind, controlled clinical trial to study the efficacy of these drug combinations in complete clearance the Mf and antigen from the blood in shorter span of 180 days and 365 days respectively.


Options:
A: Arm Label: standard treatment; Type: ACTIVE_COMPARATOR; Interventions: Drug: Diethylcarbamazine, Drug: Albendazole | Arm Label: DEC 6 mg/kg + Alb 400 mg x 1; Type: EXPERIMENTAL; Interventions: Drug: Diethylcarbamazine, Drug: Albendazole | Arm Label: DEC + ALB + IVM; Type: EXPERIMENTAL; Interventions: Drug: Diethylcarbamazine, Drug: Albendazole, Drug: Ivermectin | Intervention Type: DRUG; Name: Diethylcarbamazine; Assigned to Arm(s): DEC + ALB + IVM, DEC 6 mg/kg + Alb 400 mg x 1, standard treatment | Intervention Type: DRUG; Name: Albendazole; Assigned to Arm(s): DEC + ALB + IVM, DEC 6 mg/kg + Alb 400 mg x 1, standard treatment | Intervention Type: DRUG; Name: Ivermectin; Assigned to Arm(s): DEC + ALB + IVM
B: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Drug: albendazole + ivermectin + praziquantel | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Drug: albendazole + ivermectin + (1 week later) praziquantel | Intervention Type: DRUG; Name: albendazole + ivermectin + praziquantel; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: albendazole + ivermectin + (1 week later) praziquantel; Assigned to Arm(s): 2
C: Arm Label: DEC + ALB sequential; Type: EXPERIMENTAL; Interventions: Drug: Diethylcarbamazine, Drug: Albendazole | Arm Label: DEC + ALB co-admin; Type: EXPERIMENTAL; Interventions: Drug: Diethylcarbamazine, Drug: Albendazole | Arm Label: DEC + DOXY co-admin; Type: EXPERIMENTAL; Interventions: Drug: Diethylcarbamazine, Drug: Doxycycline | Arm Label: Diethylcarbamazine (DEC); Type: ACTIVE_COMPARATOR; Interventions: Drug: Diethylcarbamazine | Intervention Type: DRUG; Name: Diethylcarbamazine; Assigned to Arm(s): DEC + ALB co-admin, DEC + ALB sequential, DEC + DOXY co-admin, Diethylcarbamazine (DEC) | Intervention Type: DRUG; Name: Albendazole; Assigned to Arm(s): DEC + ALB co-admin, DEC + ALB sequential | Intervention Type: DRUG; Name: Doxycycline; Assigned to Arm(s): DEC + DOXY co-admin
D: Arm Label: albendazole 400mg and ivermectin 200mcg/kg; Type: ACTIVE_COMPARATOR; Interventions: Drug: Albendazole 400mg and ivermectin 200mcg/kg | Arm Label: Albendazole 800mg and ivermectin 400mcg/kg; Type: ACTIVE_COMPARATOR; Interventions: Drug: Albendazole and ivermectin | Arm Label: Albendazole 400mg and ivermectin 200mcg/kg; Type: ACTIVE_COMPARATOR; Interventions: Drug: Albendazole 400mg and ivermectin 200mcg/kg | Arm Label: Albendazole 800mg and ivermectin 400mcg /kg bi-annually; Type: ACTIVE_COMPARATOR; Interventions: Drug: albendazole 800mg and ivermectin 400mcg/kg bi-annually | Intervention Type: DRUG; Name: Albendazole 400mg and ivermectin 200mcg/kg; Assigned to Arm(s): Albendazole 400mg and ivermectin 200mcg/kg, albendazole 400mg and ivermectin 200mcg/kg | Intervention Type: DRUG; Name: Albendazole and ivermectin; Assigned to Arm(s): Albendazole 800mg and ivermectin 400mcg/kg | Intervention Type: DRUG; Name: Albendazole 400mg and ivermectin 200mcg/kg; Assigned to Arm(s): Albendazole 400mg and ivermectin 200mcg/kg, albendazole 400mg and ivermectin 200mcg/kg | Intervention Type: DRUG; Name: albendazole 800mg and ivermectin 400mcg/kg bi-annually; Assigned to Arm(s): Albendazole 800mg and ivermectin 400mcg /kg bi-annually

Answer: C