TrialPanorama/Dataset huggingface dataset:
Please select the outcome measures that correspond to the clinical trial below.
Title: Clinical and Social-economic Impact Assessment of Robot-assisted Rehabilitation of the Upper Limb in Acute and Subacute Post-stroke Patients
Brief Summary: The goal of this study is to determine if robot aided rehabilitation therapy can be equivalent to or more effective than conventional rehabilitation therapy at promoting functional recovery of the paretic upper limb in acute and subacute stroke patients.


Options:
A: Fugl-Meyer (FM-SEC and FM-WH) (7 months); Motor-Functional Independence Measure (m-FIM) (7 months); Frenchay Arm Test (FA-T) (7 months)
B: Wolf Motor Function Test (8 Weeks)
C: Action Research Arm Test (ARAT) (End of treatment at 8 weeks post enrolment)
D: Fugl-Meyer Assessment for Motor Recovery (FM) Scale (6, 12, 24 and 36 weeks minus baseline)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Clinical and Social-economic Impact Assessment of Robot-assisted Rehabilitation of the Upper Limb in Acute and Subacute Post-stroke Patients
Brief Summary: The goal of this study is to determine if robot aided rehabilitation therapy can be equivalent to or more effective than conventional rehabilitation therapy at promoting functional recovery of the paretic upper limb in acute and subacute stroke patients.


Options:
A: Fugl-Meyer (FM-SEC and FM-WH) (7 months); Motor-Functional Independence Measure (m-FIM) (7 months); Frenchay Arm Test (FA-T) (7 months)
B: Action Research Arm Test (ARAT) (End of treatment at 8 weeks post enrolment)
C: Length of outpatient rehab stay (LOS) (From admission to discharge, an expected average of 5 weeks.)
D: Fugl_Meyer Upper Extremity scale (F-M UE) (20 min)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Clinical and Social-economic Impact Assessment of Robot-assisted Rehabilitation of the Upper Limb in Acute and Subacute Post-stroke Patients
Brief Summary: The goal of this study is to determine if robot aided rehabilitation therapy can be equivalent to or more effective than conventional rehabilitation therapy at promoting functional recovery of the paretic upper limb in acute and subacute stroke patients.


Options:
A: Change from Baseline in Fugl-Meyer Scale at 28 weeks. (at inclusion, week 4 and week 28); Change from Baseline in Box and Block Test at 28 weeks. (at inclusion, week 4 and week 28.)
B: Fugl-Meyer (FM-SEC and FM-WH) (7 months); Motor-Functional Independence Measure (m-FIM) (7 months); Frenchay Arm Test (FA-T) (7 months)
C: Movement time (Baseline and change from baseline in movement time at 4 weeks); Motor units (Baseline and change from baseline in motor units at 4 weeks); Elbow extension angle (Baseline and change from baseline in elbow extension angle at 4 weeks); Lateral index (Baseline and change from baseline in lateral index at 4 weeks)
D: Action Research Arm Test (ARAT) (End of treatment at 8 weeks post enrolment)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Evaluation Study of Unilateral Bronchoscopic Thermal Vapor Ablation (BTVA) in Patients With Heterogeneous Emphysema and Upper Lobe Predominance
Brief Summary: To establish and confirm the safety and clinical utility of BTVA applied unilaterally for lung volume reduction in patients with upper lobe predominate heterogeneous severe emphysema.


Options:
A: Meters: 6 Minute Walk Test - Change From Baseline to 12 Months Follow up (baseline through 12 months follow up)
B: Forced Expiratory Volume in 1 second (FEV1) (12 Months)
C: increase in FEV1 ≥ 12% or a decrease in total St. George's Respiratory Questionnaire (SGRQ) score ≥ 4 points (6 months)
D: St. George's Respiratory Questionnaire (SGRQ) (three month Follow-Up Visit)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Prolonged Exposure (PE) for PTSD: Telemedicine vs. In Person
Brief Summary: The present proposal is to study whether Prolonged Exposure (PE) delivered via Telemedicine is as effective as PE delivered In Person for Operation Iraqi Freedom (OIF), Operation Enduring Freedom (OEF) Veterans and Veterans of all theatres, particularly Vietnam era with Post-Traumatic Stress Disorder (PTSD). ).


Options:
A: Treatment Completion (13 weeks); PTSD Checklist-Military (PCL-M) (26 weeks); Beck Depression Inventory-II (BDI-II) (26 weeks)
B: Change in medication adherence (Baseline, 6 months, 9 months, 12 months, 15 months, and 18 months); Change in number of hospitalizations (costs) (Baseline, 6 months, 9 months, 12 months, 15 months, and 18 months)
C: Dyspnea; Exercise adherence and performance; Pulmonary exacerbations
D: Percentage of subjects with average day-time ambulatory blood pressure <135/85 mmHg (6 months); Percentage of subjects with average day-time ambulatory blood pressure <135/85 mmHg (12 months)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Effectiveness of an Automated Walking Program Targeting Veterans With COPD
Brief Summary: The purpose of this study is to assess the efficacy of an internet-mediated pedometer based intervention that is designed to increase walking and improve function among veterans with chronic obstructive pulmonary disease (COPD). The Specific Aims are: 1) to test the effectiveness of an automated internet-mediated walking program for veterans with COPD with a primary outcome of improvement in health-related quality of life at four-months and at one year in a randomized controlled trial (RCT) with a wait list control. 2) to estimate the effect of internet-mediated walking program for veterans with COPD on all cause days of hospitalization over one year following randomization. 3) to compare intervention reach, participation and satisfaction outcomes between rural and urban veterans among those randomized to the intervention arm. The long-term objective of this research is to develop, evaluate and disseminate effective, low-cost interventions that improve quality of life for veterans, particularly rural veterans, managing complex chronic conditions.


Options:
A: Self-Reported Respiratory-Specific Quality of Life (four months from randomization); Self-Reported Respiratory-Specific Quality of Life (twelve months from randomization)
B: Dyspnea (Chronic Respiratory Questionnaire (CRQ) domain) (Change from baseline to 12 months)
C: Total cost of hospitalization, $ (Day of admission to day of discharge)
D: Change From Baseline in Lung Function as Measured by the Forced Expiratory Volume in 1 Second (FEV1) Area Under the Curve From 0-3h (AUC0-3h) (baseline, week 24)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Effectiveness of an Automated Walking Program Targeting Veterans With COPD
Brief Summary: The purpose of this study is to assess the efficacy of an internet-mediated pedometer based intervention that is designed to increase walking and improve function among veterans with chronic obstructive pulmonary disease (COPD). The Specific Aims are: 1) to test the effectiveness of an automated internet-mediated walking program for veterans with COPD with a primary outcome of improvement in health-related quality of life at four-months and at one year in a randomized controlled trial (RCT) with a wait list control. 2) to estimate the effect of internet-mediated walking program for veterans with COPD on all cause days of hospitalization over one year following randomization. 3) to compare intervention reach, participation and satisfaction outcomes between rural and urban veterans among those randomized to the intervention arm. The long-term objective of this research is to develop, evaluate and disseminate effective, low-cost interventions that improve quality of life for veterans, particularly rural veterans, managing complex chronic conditions.


Options:
A: disease-specific health-related quality of life (HRQoL) (two years)
B: Self-Reported Respiratory-Specific Quality of Life (four months from randomization); Self-Reported Respiratory-Specific Quality of Life (twelve months from randomization)
C: Evaluation of effects (T1: Initial evaluation; T2: after three months; T3: one year after T1)
D: Adverse events (Evaluation at 12 months.)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Effectiveness of an Automated Walking Program Targeting Veterans With COPD
Brief Summary: The purpose of this study is to assess the efficacy of an internet-mediated pedometer based intervention that is designed to increase walking and improve function among veterans with chronic obstructive pulmonary disease (COPD). The Specific Aims are: 1) to test the effectiveness of an automated internet-mediated walking program for veterans with COPD with a primary outcome of improvement in health-related quality of life at four-months and at one year in a randomized controlled trial (RCT) with a wait list control. 2) to estimate the effect of internet-mediated walking program for veterans with COPD on all cause days of hospitalization over one year following randomization. 3) to compare intervention reach, participation and satisfaction outcomes between rural and urban veterans among those randomized to the intervention arm. The long-term objective of this research is to develop, evaluate and disseminate effective, low-cost interventions that improve quality of life for veterans, particularly rural veterans, managing complex chronic conditions.


Options:
A: COPD Assessment Test (CAT) (Baseline and 6 months)
B: Self-Reported Respiratory-Specific Quality of Life (four months from randomization); Self-Reported Respiratory-Specific Quality of Life (twelve months from randomization)
C: Six Minute Walk Distance (6 weeks); COPD Assesment Tool (CAT) (6 weeks)
D: Patient's perception of the variability of symptoms due to severe stable state COPD throughout the day, the week and the year (Once)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Effectiveness of an Automated Walking Program Targeting Veterans With COPD
Brief Summary: The purpose of this study is to assess the efficacy of an internet-mediated pedometer based intervention that is designed to increase walking and improve function among veterans with chronic obstructive pulmonary disease (COPD). The Specific Aims are: 1) to test the effectiveness of an automated internet-mediated walking program for veterans with COPD with a primary outcome of improvement in health-related quality of life at four-months and at one year in a randomized controlled trial (RCT) with a wait list control. 2) to estimate the effect of internet-mediated walking program for veterans with COPD on all cause days of hospitalization over one year following randomization. 3) to compare intervention reach, participation and satisfaction outcomes between rural and urban veterans among those randomized to the intervention arm. The long-term objective of this research is to develop, evaluate and disseminate effective, low-cost interventions that improve quality of life for veterans, particularly rural veterans, managing complex chronic conditions.


Options:
A: Treatment Adherence (10 months)
B: Number of hospitalizations due to exacerbation of COPD avoided (1 year)
C: Self-Reported Respiratory-Specific Quality of Life (four months from randomization); Self-Reported Respiratory-Specific Quality of Life (twelve months from randomization)
D: Number of exacerbations (12 months)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Effectiveness of an Automated Walking Program Targeting Veterans With COPD
Brief Summary: The purpose of this study is to assess the efficacy of an internet-mediated pedometer based intervention that is designed to increase walking and improve function among veterans with chronic obstructive pulmonary disease (COPD). The Specific Aims are: 1) to test the effectiveness of an automated internet-mediated walking program for veterans with COPD with a primary outcome of improvement in health-related quality of life at four-months and at one year in a randomized controlled trial (RCT) with a wait list control. 2) to estimate the effect of internet-mediated walking program for veterans with COPD on all cause days of hospitalization over one year following randomization. 3) to compare intervention reach, participation and satisfaction outcomes between rural and urban veterans among those randomized to the intervention arm. The long-term objective of this research is to develop, evaluate and disseminate effective, low-cost interventions that improve quality of life for veterans, particularly rural veterans, managing complex chronic conditions.


Options:
A: Dyspnea; Exercise adherence and performance; Pulmonary exacerbations
B: Exercise behavior (3 & 6 Months)
C: Dyspnea with ADL (3, 6, and 12 months); Exercise and functional performance (3, 6, and 12 months); Exercise adherence (3, 6, and 12 months); Acute COPD exacerbations (3, 6, and 12 months)
D: Self-Reported Respiratory-Specific Quality of Life (four months from randomization); Self-Reported Respiratory-Specific Quality of Life (twelve months from randomization)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Effectiveness of an Automated Walking Program Targeting Veterans With COPD
Brief Summary: The purpose of this study is to assess the efficacy of an internet-mediated pedometer based intervention that is designed to increase walking and improve function among veterans with chronic obstructive pulmonary disease (COPD). The Specific Aims are: 1) to test the effectiveness of an automated internet-mediated walking program for veterans with COPD with a primary outcome of improvement in health-related quality of life at four-months and at one year in a randomized controlled trial (RCT) with a wait list control. 2) to estimate the effect of internet-mediated walking program for veterans with COPD on all cause days of hospitalization over one year following randomization. 3) to compare intervention reach, participation and satisfaction outcomes between rural and urban veterans among those randomized to the intervention arm. The long-term objective of this research is to develop, evaluate and disseminate effective, low-cost interventions that improve quality of life for veterans, particularly rural veterans, managing complex chronic conditions.


Options:
A: Chronic Respiratory Questionnaire (At least 5 years)
B: Hospital readmission rate (all cause) (90 days)
C: Self-Reported Respiratory-Specific Quality of Life (four months from randomization); Self-Reported Respiratory-Specific Quality of Life (twelve months from randomization)
D: 6 Minutes Walk Test (9 weeks)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Evaluation of the Effects of Post-Session Administration of D-cycloserine On Exposure Therapy Outcomes
Brief Summary: The purpose of this study is to investigate the utility of post-session administration of D-cycloserine to enhance fear extinction in a sample of people with acrophobia who will be treated with CBT.


Options:
A: Liebowitz Social Anxiety Scale (LSAS) (Week 13); CGI - Clinical Global Impression of Improvement (Week 13)
B: significant reduction in panic symptoms after completion of treatment
C: Acrophobia Questionnaire With Avoidance (AAVQ) (2 months)
D: Snake Questionnaire (SNAQ) (2 weeks)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: An Exercise Intervention to Improve Health in Postmenopausal Cancer Survivors
Brief Summary: The purpose of the study is to evaluate the effect of an aerobic-resistance exercise program compared to a home based physical activity program on bone mass, body composition, metabolic risk factors and cardiovascular fitness in women with cancer who have completed therapy.


Options:
A: Bone mass-lumbar spine and hip (DEXA) (baseline, 12 months)
B: Stimulated ln (TNF-a) (Immediately post-treatment and 3 months post-treatment); Stimulated ln (IL-6) (Immediately post-treatment and 3 months post-treatment); Stimulated ln (IL-1b) (Immediately post-treatment and 3 months post-treatment); MFSI-SF Fatigue (Immediately post-treatment and 3 months post-treatment); Vitality, SF-36 (Immediately post-treatment and 3 months post-treatment); CES-D (Immediately post-treatment and 3 months post-treatment)
C: Specific aim 1: To determine whether there are any changes in lymphedema in breast cancer survivors who participate in a one-year randomized exercise intervention of twice-weekly strength training, as compared to a non-exercising group. (1 year)
D: Change from Baseline in Arthralgia Severity (6 months); Change from Baseline in Arthralgia Severity (12 months)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: An Exercise Intervention to Improve Health in Postmenopausal Cancer Survivors
Brief Summary: The purpose of the study is to evaluate the effect of an aerobic-resistance exercise program compared to a home based physical activity program on bone mass, body composition, metabolic risk factors and cardiovascular fitness in women with cancer who have completed therapy.


Options:
A: Bone mass-lumbar spine and hip (DEXA) (baseline, 12 months)
B: Change from Baseline in Arthralgia Severity (6 months); Change from Baseline in Arthralgia Severity (12 months)
C: Proportion of participants with completed assessments at 6 months (6 months)
D: Breast Cancer Recurrence (Lifetime)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: SSRIs and Self-harm in Borderline Personality Disorder
Brief Summary: The goal of this study is to examine the effectiveness the selective serotonin reuptake inhibitor (SSRI) escitalopram (also known by the trade name "Lexapro") in reducing desire to self-harm and actual self-harming among young adults with borderline personality disorder who are also currently depressed. Subjects will receive either escitalopram or placebo for eight weeks. During this time subjects will be make weekly visits to see the psychiatrist and record their thoughts and feelings several times each day using an electronic diary.


Options:
A: Change From Baseline in the Zanarini Rating Scale for Borderline Personality Disorder (ZAN-BPD) Total Score (Baseline (Day 0) to Week 10)
B: Change in frequency of self-harm (suicidal and non-suicidal) behaviours over time as measured by the Suicide Attempt Self-Injury Interview (SASII) (Administered pre-treatment and every three months until 24 months)
C: Self-harm Ideation (pre-treatment (week 0) to post-treatment (end of week 8))
D: Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors (Assessed at completion of inpatient treatment (average of 12 days), and on a monthly basis for 6 months follow-up.); Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors (Assessed at completion of inpatient treatment (average of 12 days), and on a monthly basis for 6 months follow-up.); The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe (Assessed at completion of inpatient treatment (average of 12 days), and on a monthly basis for 6 months follow-up.); Columbia Suicide Severity Rating Scale Suicidal Ideation Intensity Scale Total Score (Assessed at completion of inpatient treatment (average of 12 days), and on a monthly basis for 6 months follow-up.); Number of Participants With Readmissions (Assessed on a monthly basis for 6 months follow-up.)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: SSRIs and Self-harm in Borderline Personality Disorder
Brief Summary: The goal of this study is to examine the effectiveness the selective serotonin reuptake inhibitor (SSRI) escitalopram (also known by the trade name "Lexapro") in reducing desire to self-harm and actual self-harming among young adults with borderline personality disorder who are also currently depressed. Subjects will receive either escitalopram or placebo for eight weeks. During this time subjects will be make weekly visits to see the psychiatrist and record their thoughts and feelings several times each day using an electronic diary.


Options:
A: Remission From Major Depressive Episode in Intent to Treat Sample (Up to 12 Weeks); Remission From Major Depressive Episode Among Participants Who Completed the Intervention (Measured at Weeks 10 and 12)
B: The Zanarini Rating Scale for Borderline Personality Disorder (Weeks 0, 2, 4, 6, 8, 10, 12); Borderline Evaluation of Severity over Time (BEST) (Weeks 0,2,4,6,8,10,12)
C: Suicide Attempt Behavior (12-month observation period)
D: Self-harm Ideation (pre-treatment (week 0) to post-treatment (end of week 8))

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Nutrition, Growth and Development Among Very Preterm Infants
Brief Summary: The main purpose of this study is to evaluate the effect of increased supply of energy, protein, vitamin A and the long chain polyunsaturated fatty acids docosahexaenoic acid and arachidonic acid on growth, brain maturation and cognitive function.


Options:
A: Weight gain due to fat mass (4 weeks)
B: Reduction in discharge rate of small-for-gestational age very low birth weight infants (6 months corrected age)
C: Daily growth velocity (g/kg/day) (From the beginning of human milk fortification until the end of hospitalization (mean period of treatment 4-5 weeks))
D: growth during first three weeks of intervention (first three weeks during intervention before 36 weeks of gestation)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Nutrition, Growth and Development Among Very Preterm Infants
Brief Summary: The main purpose of this study is to evaluate the effect of increased supply of energy, protein, vitamin A and the long chain polyunsaturated fatty acids docosahexaenoic acid and arachidonic acid on growth, brain maturation and cognitive function.


Options:
A: Average duration of exposure to PN (including Intralipid, IL) between the initial feeding and bowel reanastomosis (up to three years)
B: Reduction in discharge rate of small-for-gestational age very low birth weight infants (6 months corrected age)
C: time of achieving the four gross motor development milestones (4, 8 and 12 months of age)
D: visual development

Answer: B