TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Intradialytic Pedalling Exercise and Vascular Hemodynamic Parameters Among Prevalent Hemodialysis Population
Brief Summary: The purpose of this pilot study is to evaluate 1) the effect of intradialytic pedaling exercise on arterial stiffness and other arterial hemodynamic parameters over 4 months, and 2) the longer-term effect of pedaling on arterial stiffness and other arterial hemodynamic parameters 4 months after finishing the exercise intervention (8 months after study initiation).

The investigators also aim to examine the impact of intradialytic pedaling exercise on general health, anthropometric measures, physical function, and routine laboratory blood markers as secondary outcome measures, as well as to assess feasibility, safety and adverse events associated with the intradialytic pedalling exercise.

Recruitment of more participants in the future will be considered if warranted.


Options:
A: Arm Label: pedometer; Type: EXPERIMENTAL; Interventions: Behavioral: pedometer | Arm Label: usual care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: pedometer; Assigned to Arm(s): pedometer
B: Arm Label: exercise training; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise training | Arm Label: controls; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Exercise training; Assigned to Arm(s): exercise training
C: Arm Label: HD-Exercise-HDF; Type: EXPERIMENTAL; Interventions: Procedure: Intra-dialytic exercise | Intervention Type: PROCEDURE; Name: Intra-dialytic exercise; Assigned to Arm(s): HD-Exercise-HDF
D: Arm Label: Exercise; Type: EXPERIMENTAL; Interventions: Other: Exercise | Arm Label: Usual care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Exercise; Assigned to Arm(s): Exercise

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A 52-week Open-label (Sponsor-blind), Randomized, Active-controlled, Parallel-group, Multi-center Study to Evaluate the Efficacy and Safety of Daprodustat Compared to Recombinant Human Erythropoietin in Subjects With Anemia Associated With Chronic Kidney Disease Who Are Initiating Dialysis
Brief Summary: The purpose of this multi-center study is to evaluate the efficacy and safety of daprodustat in subjects with anemia associated with CKD.


Options:
A: Arm Label: ASP1517 Low dose group; Type: EXPERIMENTAL; Interventions: Drug: roxadustat | Arm Label: ASP1517 Middle dose group; Type: EXPERIMENTAL; Interventions: Drug: roxadustat | Arm Label: ASP1517 High dose group; Type: EXPERIMENTAL; Interventions: Drug: roxadustat | Arm Label: Darbepoetin group; Type: ACTIVE_COMPARATOR; Interventions: Drug: darbepoetin alfa | Intervention Type: DRUG; Name: roxadustat; Assigned to Arm(s): ASP1517 High dose group, ASP1517 Low dose group, ASP1517 Middle dose group | Intervention Type: DRUG; Name: darbepoetin alfa; Assigned to Arm(s): Darbepoetin group
B: Arm Label: Roxadustat; Type: EXPERIMENTAL; Interventions: Drug: Roxadustat | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Roxadustat; Assigned to Arm(s): Roxadustat | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
C: Arm Label: Daprodustat treated anemic subjects; Type: EXPERIMENTAL; Interventions: Drug: Daprodustat, Drug: Iron therapy | Arm Label: Darbepoetin alfa treated anemic subjects; Type: ACTIVE_COMPARATOR; Interventions: Drug: Darbepoetin alfa, Drug: Iron therapy | Intervention Type: DRUG; Name: Daprodustat; Assigned to Arm(s): Daprodustat treated anemic subjects | Intervention Type: DRUG; Name: Darbepoetin alfa; Assigned to Arm(s): Darbepoetin alfa treated anemic subjects | Intervention Type: DRUG; Name: Iron therapy; Assigned to Arm(s): Daprodustat treated anemic subjects, Darbepoetin alfa treated anemic subjects
D: Arm Label: FG-4592; Type: EXPERIMENTAL; Interventions: Drug: FG-4592 | Arm Label: Epoetin alfa; Type: ACTIVE_COMPARATOR; Interventions: Drug: Epoetin Alfa | Intervention Type: DRUG; Name: FG-4592; Assigned to Arm(s): FG-4592 | Intervention Type: DRUG; Name: Epoetin Alfa; Assigned to Arm(s): Epoetin alfa

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: ENGAGED 2 Study: Experiences With Mammography Screening and Breast Density 2
Brief Summary: This trial will test a decision support web based intervention for women at increased risk for breast cancer due to breast density and other risk factors (age, race/ethnicity, family history of breast cancer, history of prior breast biopsies), and to consider MRI and/or chemoprevention to manage their breast cancer risk.


Options:
A: Arm Label: Shared Decision Making/Brief Negotiated Interviewing; Type: OTHER; Interventions: Behavioral: Shared Decision Making | Arm Label: Control Arm; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Shared Decision Making; Assigned to Arm(s): Shared Decision Making/Brief Negotiated Interviewing
B: Arm Label: 3-9 months PPIUD intervention; Type: EXPERIMENTAL; Interventions: Device: Post-partum IUD | Arm Label: 9-15 months PPIUD intervention; Type: EXPERIMENTAL; Interventions: Device: Post-partum IUD | Intervention Type: DEVICE; Name: Post-partum IUD; Assigned to Arm(s): 3-9 months PPIUD intervention, 9-15 months PPIUD intervention
C: Arm Label: Personalized Web Intervention Arm; Type: EXPERIMENTAL; Interventions: Behavioral: Personalized Web Intervention Arm | Arm Label: Usual Care Arm; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Usual Care Arm | Intervention Type: BEHAVIORAL; Name: Usual Care Arm; Assigned to Arm(s): Usual Care Arm | Intervention Type: BEHAVIORAL; Name: Personalized Web Intervention Arm; Assigned to Arm(s): Personalized Web Intervention Arm
D: Arm Label: Rapid genetic counseling; Type: EXPERIMENTAL; Interventions: Behavioral: counseling intervention, Other: educational intervention, Procedure: psychosocial assessment and care | Arm Label: Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: counseling intervention; Assigned to Arm(s): Rapid genetic counseling | Intervention Type: OTHER; Name: educational intervention; Assigned to Arm(s): Rapid genetic counseling | Intervention Type: PROCEDURE; Name: psychosocial assessment and care; Assigned to Arm(s): Rapid genetic counseling

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: iQuit Mindfully: A Randomized Controlled Trial of Mindfulness-based Smoking Cessation Enhanced With Mobile Technology
Brief Summary: The purpose of this study is to investigate text messaging as a way to enhance mindfulness-based treatment for smoking cessation.


Options:
A: Arm Label: Mindfulness; Type: EXPERIMENTAL; Interventions: Behavioral: Mindfulness-based intervention | Arm Label: Sham meditation; Type: SHAM_COMPARATOR; Interventions: Behavioral: Sham meditation | Arm Label: Treatment as usual; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Mindfulness-based intervention; Assigned to Arm(s): Mindfulness | Intervention Type: BEHAVIORAL; Name: Sham meditation; Assigned to Arm(s): Sham meditation
B: Arm Label: Experimental App; Type: EXPERIMENTAL; Interventions: Behavioral: Experimental App | Arm Label: Active comparator app; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Active Comparator App | Intervention Type: BEHAVIORAL; Name: Experimental App; Assigned to Arm(s): Experimental App | Intervention Type: BEHAVIORAL; Name: Active Comparator App; Assigned to Arm(s): Active comparator app
C: Arm Label: Enhanced health education program; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Enhanced health education | Arm Label: Transcendental Meditation program; Type: EXPERIMENTAL; Interventions: Behavioral: Transcendental Meditation program | Intervention Type: BEHAVIORAL; Name: Enhanced health education; Assigned to Arm(s): Enhanced health education program | Intervention Type: BEHAVIORAL; Name: Transcendental Meditation program; Assigned to Arm(s): Transcendental Meditation program
D: Arm Label: Mindfulness-based Addiction Treatment (MBAT); Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Mindfulness-based Addiction Treatment, Behavioral: Self-Help guide, Drug: Nicotine Patch | Arm Label: iQuit Mindfully; Type: EXPERIMENTAL; Interventions: Behavioral: Mindfulness-based Addiction Treatment, Behavioral: iQuit Mindfully, Behavioral: Self-Help guide, Drug: Nicotine Patch | Intervention Type: BEHAVIORAL; Name: Mindfulness-based Addiction Treatment; Assigned to Arm(s): Mindfulness-based Addiction Treatment (MBAT), iQuit Mindfully | Intervention Type: BEHAVIORAL; Name: iQuit Mindfully; Assigned to Arm(s): iQuit Mindfully | Intervention Type: BEHAVIORAL; Name: Self-Help guide; Assigned to Arm(s): Mindfulness-based Addiction Treatment (MBAT), iQuit Mindfully | Intervention Type: DRUG; Name: Nicotine Patch; Assigned to Arm(s): Mindfulness-based Addiction Treatment (MBAT), iQuit Mindfully

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: iQuit Mindfully: A Randomized Controlled Trial of Mindfulness-based Smoking Cessation Enhanced With Mobile Technology
Brief Summary: The purpose of this study is to investigate text messaging as a way to enhance mindfulness-based treatment for smoking cessation.


Options:
A: Arm Label: Mindfulness-Based Treatment Group (MBAT); Type: EXPERIMENTAL; Interventions: Behavioral: MBAT Group Therapy, Drug: Nicotine | Arm Label: Standard Care Group; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine, Behavioral: Group Therapy | Arm Label: Usual Care Group; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine, Behavioral: Individual Therapy | Intervention Type: BEHAVIORAL; Name: MBAT Group Therapy; Assigned to Arm(s): Mindfulness-Based Treatment Group (MBAT) | Intervention Type: DRUG; Name: Nicotine; Assigned to Arm(s): Mindfulness-Based Treatment Group (MBAT), Standard Care Group, Usual Care Group | Intervention Type: BEHAVIORAL; Name: Group Therapy; Assigned to Arm(s): Standard Care Group | Intervention Type: BEHAVIORAL; Name: Individual Therapy; Assigned to Arm(s): Usual Care Group
B: Arm Label: Mindfulness-based Addiction Treatment (MBAT); Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Mindfulness-based Addiction Treatment, Behavioral: Self-Help guide, Drug: Nicotine Patch | Arm Label: iQuit Mindfully; Type: EXPERIMENTAL; Interventions: Behavioral: Mindfulness-based Addiction Treatment, Behavioral: iQuit Mindfully, Behavioral: Self-Help guide, Drug: Nicotine Patch | Intervention Type: BEHAVIORAL; Name: Mindfulness-based Addiction Treatment; Assigned to Arm(s): Mindfulness-based Addiction Treatment (MBAT), iQuit Mindfully | Intervention Type: BEHAVIORAL; Name: iQuit Mindfully; Assigned to Arm(s): iQuit Mindfully | Intervention Type: BEHAVIORAL; Name: Self-Help guide; Assigned to Arm(s): Mindfulness-based Addiction Treatment (MBAT), iQuit Mindfully | Intervention Type: DRUG; Name: Nicotine Patch; Assigned to Arm(s): Mindfulness-based Addiction Treatment (MBAT), iQuit Mindfully
C: Arm Label: Experimental; Type: EXPERIMENTAL; Interventions: Behavioral: Smartphone-delivered Intervention (SmartQuit) | Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: : Smartphone-delivered Intervention (Standard of care app) | Intervention Type: BEHAVIORAL; Name: Smartphone-delivered Intervention (SmartQuit); Assigned to Arm(s): Experimental | Intervention Type: BEHAVIORAL; Name: : Smartphone-delivered Intervention (Standard of care app); Assigned to Arm(s): Control
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: yoga, Behavioral: cognitive therapy | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: cognitive therapy, Behavioral: wellness | Intervention Type: BEHAVIORAL; Name: yoga; Assigned to Arm(s): 1 | Intervention Type: BEHAVIORAL; Name: cognitive therapy; Assigned to Arm(s): 1, 2 | Intervention Type: BEHAVIORAL; Name: yoga; Assigned to Arm(s): 1 | Intervention Type: BEHAVIORAL; Name: wellness; Assigned to Arm(s): 2

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effect of Breastfeeding Education and Support Intervention on Timely Initiation and Exclusive Breastfeeding in Southwest Ethiopia: a Cluster Randomized Controlled Trial.
Brief Summary: The purpose of this study is to develop and test Breastfeeding Education and Support Intervention for improving timely initiation and Exclusive Breastfeeding rate.

Infant mortality rates are still high in Ethiopia. Breastfeeding (BF) is regarded as the simplest and least expensive strategy for reduction of infant mortality rates. Ethiopia does not meet the international recommendation for exclusive breastfeeding (EBF) for the first six months of life. Community-based educational and support interventions provided prenatally and postnatally are effective in increasing BF rates. However, there is paucity of such information in Ethiopia.


Options:
A: Arm Label: A&T- intensive; Type: EXPERIMENTAL; Interventions: Behavioral: Maternal Nutrition Behavior change | Arm Label: A&T-non intensive; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Maternal Nutrition Behavior change; Assigned to Arm(s): A&T- intensive
B: Arm Label: Arm 1: BCC+PNS+CNS; Type: EXPERIMENTAL; Interventions: Behavioral: Nutrition-specific Behaviour change communication (BCC), Dietary Supplement: Nutrient supplement to pregnant women (PNS), Dietary Supplement: Nutrienr supplement to children 6m to 2 years | Arm Label: Arm 2: BCC+PNS; Type: EXPERIMENTAL; Interventions: Behavioral: Nutrition-specific Behaviour change communication (BCC), Dietary Supplement: Nutrient supplement to pregnant women (PNS) | Arm Label: Arm 3: BCC+CNS; Type: EXPERIMENTAL; Interventions: Behavioral: Nutrition-specific Behaviour change communication (BCC), Dietary Supplement: Nutrienr supplement to children 6m to 2 years | Arm Label: Arm 4: BCC only; Type: EXPERIMENTAL; Interventions: Behavioral: Nutrition-specific Behaviour change communication (BCC) | Arm Label: Arm 5: comparison; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Nutrition-specific Behaviour change communication (BCC); Assigned to Arm(s): Arm 1: BCC+PNS+CNS, Arm 2: BCC+PNS, Arm 3: BCC+CNS, Arm 4: BCC only | Intervention Type: DIETARY_SUPPLEMENT; Name: Nutrient supplement to pregnant women (PNS); Assigned to Arm(s): Arm 1: BCC+PNS+CNS, Arm 2: BCC+PNS | Intervention Type: DIETARY_SUPPLEMENT; Name: Nutrienr supplement to children 6m to 2 years; Assigned to Arm(s): Arm 1: BCC+PNS+CNS, Arm 3: BCC+CNS
C: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: LC and Electronic Prompt | Arm Label: 2; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: LC and Electronic Prompt; Assigned to Arm(s): 1
D: Arm Label: Breastfeeding Education and Support; Type: EXPERIMENTAL; Interventions: Behavioral: Breastfeeding Education and Support | Arm Label: Usual or routine care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Breastfeeding Education and Support; Assigned to Arm(s): Breastfeeding Education and Support

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Zahra Teymuri, Zahedan University of Medical Sciences
Brief Summary: The purpose of this study was to evaluate the effects of stabilization exercises on pain, disability and pelvic floor muscles function in patients with lumbopelvic pain.


Options:
A: Arm Label: Lifestyle intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Physical Exercise / Physical Activity | Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Physical Exercise / Physical Activity; Assigned to Arm(s): Lifestyle intervention
B: Intervention Type: BEHAVIORAL; Name: Supervised exercise for the prevention high weight gain; Assigned to Arm(s): N/A
C: Arm Label: stabilization exercises; Type: EXPERIMENTAL; Interventions: Other: Stabilization exercise | Arm Label: control group; Type: EXPERIMENTAL; Interventions: Other: Control group | Intervention Type: OTHER; Name: Stabilization exercise; Assigned to Arm(s): stabilization exercises | Intervention Type: OTHER; Name: Control group; Assigned to Arm(s): control group
D: Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Exercise Group; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise Group | Intervention Type: BEHAVIORAL; Name: Exercise Group; Assigned to Arm(s): Exercise Group

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Efficacy of Glycine Powder Air-Polishing Combined With Scaling and Root Planing in the Treatment of Periodontitis and Halitosis: A Randomized Clinical Study
Brief Summary: The aim of this clinical study was to evaluate the clinical efficacy of using perio flow adjunctively with mechanical instrumentation on periodontal parameters and halitosis.

Sixty patients who presented with 4-6-mm probing pocket depth (PPD) were recruited for the study. Patients were randomly assigned to glycine powder air-polishing (GPAP) or control groups. For both groups PPDscores were recorded at the baseline and 1 month. Volatile sulphur compound (VSC) values were measured by a halimeter at the baseline, immediately after treatment, and at 7 days, 14 days and 1 month.


Options:
A: Arm Label: group 1: drug; Type: EXPERIMENTAL; Interventions: Drug: group 1: drug: chlorine dioxide | Arm Label: group 2: device:; Type: EXPERIMENTAL; Interventions: Device: group 2: device: small tooth brush for tongue cleaning | Intervention Type: DRUG; Name: group 1: drug: chlorine dioxide; Assigned to Arm(s): group 1: drug | Intervention Type: DEVICE; Name: group 2: device: small tooth brush for tongue cleaning; Assigned to Arm(s): group 2: device:
B: Intervention Type: OTHER; Name: Chlorine Dioxide; Assigned to Arm(s): N/A
C: Arm Label: test; Type: EXPERIMENTAL; Interventions: Device: glycine powder air-polishing (Air-Flows)Perio Powder, Device: ultrasonic (Piezon Master 700; EMS, Nyon, Switzerland) | Arm Label: control; Type: ACTIVE_COMPARATOR; Interventions: Device: ultrasonic (Piezon Master 700; EMS, Nyon, Switzerland) | Intervention Type: DEVICE; Name: glycine powder air-polishing (Air-Flows)Perio Powder; Assigned to Arm(s): test | Intervention Type: DEVICE; Name: ultrasonic (Piezon Master 700; EMS, Nyon, Switzerland); Assigned to Arm(s): control, test
D: Intervention Type: OTHER; Name: Chlorine Dioxide; Assigned to Arm(s): N/A

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Randomized, Blinded Trial Comparing Vaginal Estrogens on Pelvic Organ Prolapse Patients
Brief Summary: To evaluate the difference of three vaginal estrogens creams comparative with placebo on improvement of hormonal cytology, local and systemic climacteric complaints, as well as its endometrial security.


Options:
A: Arm Label: Vaginal estrogen cream; Type: EXPERIMENTAL; Interventions: Drug: Vaginal Cream with Applicator [Dose Form] | Arm Label: vaginal placebo cream; Type: PLACEBO_COMPARATOR; Interventions: Drug: Vaginal Cream with Applicator [Dose Form] | Intervention Type: DRUG; Name: Vaginal Cream with Applicator [Dose Form]; Assigned to Arm(s): Vaginal estrogen cream, vaginal placebo cream
B: Arm Label: Conjugated Estrogen Group; Type: ACTIVE_COMPARATOR; Interventions: Drug: Promestriene, Drug: Estriol, Drug: Vaginal Moisturizer - Cream | Arm Label: Promestriene Group; Type: ACTIVE_COMPARATOR; Interventions: Drug: Conjugated Estrogen, Drug: Estriol, Drug: Vaginal Moisturizer - Cream | Arm Label: Estriol Group; Type: ACTIVE_COMPARATOR; Interventions: Drug: Conjugated Estrogen, Drug: Promestriene, Drug: Vaginal Moisturizer - Cream | Arm Label: Vaginal Moisturizer Cream; Type: PLACEBO_COMPARATOR; Interventions: Drug: Conjugated Estrogen, Drug: Promestriene, Drug: Estriol | Intervention Type: DRUG; Name: Conjugated Estrogen; Assigned to Arm(s): Estriol Group, Promestriene Group, Vaginal Moisturizer Cream | Intervention Type: DRUG; Name: Promestriene; Assigned to Arm(s): Conjugated Estrogen Group, Estriol Group, Vaginal Moisturizer Cream | Intervention Type: DRUG; Name: Estriol; Assigned to Arm(s): Conjugated Estrogen Group, Promestriene Group, Vaginal Moisturizer Cream | Intervention Type: DRUG; Name: Vaginal Moisturizer - Cream; Assigned to Arm(s): Conjugated Estrogen Group, Estriol Group, Promestriene Group
C: Arm Label: Intravaginal Pessary; Type: EXPERIMENTAL; Interventions: Device: Intravaginal Pessary | Arm Label: Behavioral Therapy; Type: EXPERIMENTAL; Interventions: Behavioral: Behavioral Therapy | Arm Label: Pessary combined with behavioral therapy; Type: EXPERIMENTAL; Interventions: Device: Pessary combined with behavioral therapy | Intervention Type: BEHAVIORAL; Name: Behavioral Therapy; Assigned to Arm(s): Behavioral Therapy | Intervention Type: DEVICE; Name: Intravaginal Pessary; Assigned to Arm(s): Intravaginal Pessary | Intervention Type: DEVICE; Name: Pessary combined with behavioral therapy; Assigned to Arm(s): Pessary combined with behavioral therapy
D: Arm Label: Estrogen Cream; Type: EXPERIMENTAL; Interventions: Drug: Conjugated Estrogens Cream | Arm Label: Placebo Cream; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo Cream | Intervention Type: DRUG; Name: Conjugated Estrogens Cream; Assigned to Arm(s): Estrogen Cream | Intervention Type: DRUG; Name: Placebo Cream; Assigned to Arm(s): Placebo Cream

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Optimizing Patient Centered-Care: A Pragmatic Randomized Control Trial Comparing Models of Care in the Management of Prescription Opioid Misuse (OPTIMA Trial)
Brief Summary: This trial evaluates two standard of care treatments for opioid addiction: methadone and buprenorphine/naloxone. In order to improve patient care, the study will address real-world treatment conditions, including strict regulations for methadone dosing (i.e. initially dispensed daily at the pharmacy until stabilisation) vs. flexible take-home dosing for buprenorphine/naloxone. The OPTIMA study is designed with the intention to support patient-provider decision-making and evaluate health related outcomes with the overall aim of improving treatment outcomes through enhancing patient-centered approaches in clinical care.


Options:
A: N/A
B: Arm Label: Methadone; Type: OTHER; Interventions: Drug: Methadone | Arm Label: Buprenorphine/Naloxone; Type: OTHER; Interventions: Drug: Buprenorphine-Naloxone | Intervention Type: DRUG; Name: Methadone; Assigned to Arm(s): Methadone | Intervention Type: DRUG; Name: Buprenorphine-Naloxone; Assigned to Arm(s): Buprenorphine/Naloxone
C: Arm Label: Methadone Maintenance; Type: EXPERIMENTAL; Interventions: Drug: Methadone | Arm Label: Holistic Health Recovery Program; Type: EXPERIMENTAL; Interventions: Behavioral: Holistic Health Recovery Program | Arm Label: Methadone Maintenance and Holistic Health Recovery Prorgram; Type: EXPERIMENTAL; Interventions: Drug: Methadone, Behavioral: Holistic Health Recovery Program | Arm Label: Standard of Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: Methadone; Assigned to Arm(s): Methadone Maintenance, Methadone Maintenance and Holistic Health Recovery Prorgram | Intervention Type: BEHAVIORAL; Name: Holistic Health Recovery Program; Assigned to Arm(s): Holistic Health Recovery Program, Methadone Maintenance and Holistic Health Recovery Prorgram
D: Arm Label: Group A; Type: ACTIVE_COMPARATOR; Interventions: Drug: Probuphine | Arm Label: Group B; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Intervention Type: DRUG; Name: Probuphine; Assigned to Arm(s): Group A | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Group B

Answer: B