Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Response and Adaptation to Aerobic Exercise in Patients With Pulmonary Hypertension: Initial Studies for Establishing Guidelines
Brief Summary: This study will determine if a rehabilitation exercise program can help people with pulmonary hypertension (PH) increase their physical activity. Patients with PH have an increase in blood pressure in the pulmonary blood vessels (artery, vein or capillaries) that leads to shortness of breath, dizziness, fainting and other symptoms.

Healthy volunteers and people with pulmonary hypertension between 21 and 75 years of age may be eligible for this study.

All participants undergo the following tests and procedures:

* Medical history and physical examination
* 6-minute walk test: Subjects walk as fast as they can for 6 minutes on a walking track to determine their ability to participate in physical activity.
* Questionnaires: Subjects complete nine questionnaires related to their fatigue, daily physical activity, mood, and so forth.
* Maximum treadmill test: The exercise begins at an easy level and gradually increases until the subject says he or she can no longer continue or the investigator decides it is not safe to continue. Subjects are fitted with a mask, electrodes and light sensors to measure how well the heart is working and how well the muscles use oxygen.

Patients with pulmonary hypertension undergo the following additional procedures:

* Activity monitoring: Patients wear a monitor for 3 days that measures movement and heart rate.
* Group assignment: Patients are randomly assigned to Group 1 (education plus aerobic exercise) or Group 2 (education followed by exercise).
* Group 1 patients will attend classes three days a week at either Inova Fairfax Hospital Pulmonary Rehabilitation Center or The National Institutes of Health for 10 weeks. Two sessions a week will include a 1 hour education session as well as a 30-45 minute track or treadmill exercise session. The third session will only include exercise. During the education patients will learn about a healthy lifestyle with pulmonary hypertension. After the 10 weeks of education and exercise, subjects repeat the 6-minute walk test, maximum treadmill test and questionnaires.
* Group 2 patients participate in 2; 1-hour educational session at either the Inova Pulmonary Rehabilitation Center or The National Institutes of Health for 10 weeks. After the classes, they repeat the 6-minute walk test, maximum treadmill test and questionnaires. The following 10 weeks will consist of 3 days a week of 30-45 minute track or treadmill walking at either Inova or NIH, after which they again repeat the questionnaires, treadmill and walk tests.


Options:
A: Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Exercise - Continuous Walking; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise - Continuous Walking | Arm Label: Exercise - Interval Walking; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise Training - Interval Walking | Intervention Type: BEHAVIORAL; Name: Exercise Training - Interval Walking; Assigned to Arm(s): Exercise - Interval Walking | Intervention Type: BEHAVIORAL; Name: Exercise - Continuous Walking; Assigned to Arm(s): Exercise - Continuous Walking
B: Arm Label: Basic Pedometry Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Basic Intervention | Arm Label: Enhanced Pedometry Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Enhanced Pedometry | Arm Label: Control Group; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Control Group | Intervention Type: BEHAVIORAL; Name: Basic Intervention; Assigned to Arm(s): Basic Pedometry Intervention | Intervention Type: BEHAVIORAL; Name: Enhanced Pedometry; Assigned to Arm(s): Enhanced Pedometry Intervention | Intervention Type: BEHAVIORAL; Name: Control Group; Assigned to Arm(s): Control Group
C: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Other: Aerobic exercise | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Other: Aerobic exercise | Intervention Type: OTHER; Name: Aerobic exercise; Assigned to Arm(s): 1, 2
D: Arm Label: The experimental group; Type: EXPERIMENTAL; Interventions: Behavioral: Group walking and group educational workshops | Arm Label: The control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Group walking and group educational workshops; Assigned to Arm(s): The experimental group

Answer: C