Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Prevention of Delayed Nausea A Phase III Double-Blind Placebo-Controlled Clinical Trial
Brief Summary: RATIONALE: Antiemetic drugs, such as granisetron, dexamethasone, prochlorperazine, aprepitant, and palonosetron, may help lessen or prevent nausea. It is not yet known which combination of antiemetic drugs is more effective in preventing nausea caused by chemotherapy.

PURPOSE: This randomized phase III trial is comparing different combinations of granisetron, dexamethasone, prochlorperazine, aprepitant, and palonosetron to see how well they work in preventing nausea in patients undergoing chemotherapy for breast cancer.


Options:
A: Arm Label: Placebo + Granisetron + Dexamethasone; Type: PLACEBO_COMPARATOR; Interventions: Drug: Granisetron, Drug: Dexamethasone, Drug: Placebo | Arm Label: Rolapitant; Type: EXPERIMENTAL; Interventions: Drug: Rolapitant, Drug: Granisetron, Drug: Dexamethasone | Intervention Type: DRUG; Name: Rolapitant; Assigned to Arm(s): Rolapitant | Intervention Type: DRUG; Name: Granisetron; Assigned to Arm(s): Placebo + Granisetron + Dexamethasone, Rolapitant | Intervention Type: DRUG; Name: Dexamethasone; Assigned to Arm(s): Placebo + Granisetron + Dexamethasone, Rolapitant | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo + Granisetron + Dexamethasone
B: Arm Label: Arm I; Type: ACTIVE_COMPARATOR; Interventions: Drug: dexamethasone, Drug: palonosetron hydrochloride, Drug: prochlorperazine, Drug: placebo | Arm Label: Arm II; Type: EXPERIMENTAL; Interventions: Drug: dexamethasone, Drug: granisetron hydrochloride, Drug: prochlorperazine, Drug: placebo | Arm Label: Arm III; Type: ACTIVE_COMPARATOR; Interventions: Drug: aprepitant, Drug: dexamethasone, Drug: palonosetron hydrochloride, Drug: placebo | Arm Label: Arm IV; Type: EXPERIMENTAL; Interventions: Drug: dexamethasone, Drug: palonosetron hydrochloride, Drug: prochlorperazine, Drug: placebo | Intervention Type: DRUG; Name: aprepitant; Assigned to Arm(s): Arm III | Intervention Type: DRUG; Name: dexamethasone; Assigned to Arm(s): Arm I, Arm II, Arm III, Arm IV | Intervention Type: DRUG; Name: granisetron hydrochloride; Assigned to Arm(s): Arm II | Intervention Type: DRUG; Name: palonosetron hydrochloride; Assigned to Arm(s): Arm I, Arm III, Arm IV | Intervention Type: DRUG; Name: prochlorperazine; Assigned to Arm(s): Arm I, Arm II, Arm IV | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Arm I, Arm II, Arm III, Arm IV
C: Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Drug: Dexamethasone, Drug: Placebo, Drug: Ondansetron | Arm Label: Single Dose IV; Type: EXPERIMENTAL; Interventions: Drug: Casopitant, Drug: Dexamethasone, Drug: Ondansetron | Intervention Type: DRUG; Name: Casopitant; Assigned to Arm(s): Single Dose IV | Intervention Type: DRUG; Name: Dexamethasone; Assigned to Arm(s): Control, Single Dose IV | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Control | Intervention Type: DRUG; Name: Ondansetron; Assigned to Arm(s): Control, Single Dose IV
D: Intervention Type: DRUG; Name: Palonosetron; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Granisetron; Assigned to Arm(s): N/A

Answer: B