Please select the eligibility criteria that correspond to the clinical trial below.
Title: Evaluating a Novel Working Memory Training Program to Decrease Symptoms of PTSD
Brief Summary: The study is designed to evaluate the effect of a novel computer training program on PTSD.


Options:
A: Inclusion Criteria:

Participants, both male and female, aged between 18 and 25, whom;

* have experienced CSA before the age of 16
* exhibit PTSD symptomology
* ensure PTSD symptomology is present for over three-months and primarily derived from pre-16 aged trauma
* be available for treatment-sessions on a weekly basis for up to 16-sessions - have good understanding of the English language to avoid language barriers/additional time spent with interpreters
* if taking medication, this will have been stable for a period of at least 2-months prior to therapy
* EMDR is the sole treatment for PTSD from baseline until follow-up to avoid conflict of interest

Exclusion Criteria:

Participants exhibiting;

* significant psychiatric comorbidity
* comorbid psychotic disorder
* bipolar disorder type 1
* alcohol or drug dependence
* acute suicide risk, acute PTSD from trauma within the past 6 months
* PTSD focused treatment within the past 3 months or scheduled to begin another form of PTSD treatment will be excluded
* those currently participating in research or have recently participated in conflicting research
B: Inclusion Criteria:

* Female
* Age 18-65
* Primary DSM-IV diagnosis of PTSD secondary to sexual trauma

Exclusion Criteria:

* Current trauma or PTSD-focused psychosocial treatment
* Active suicidality, evidence of substance dependence in the past 6 months
* Evidence of current or past schizophrenia
* Bipolar disorder
* Organic mental disorder
C: Inclusion Criteria:

1. Identifies as female.
2. Between the age of 18 and 65.
3. Reports a sexual assault in the last 4 weeks to 1 year.
4. Current PTSD severity of 23+ on the PSS-I-5.
5. Current heavy alcohol use (2+ heavy episodic drinking occasions \[4+ drinks on one occasion\] in past month).
6. Access to the internet and a device with a webcam.

Exclusion Criteria:

1. Current diagnosis of schizophrenia, delusional disorder, or organic mental disorder as defined by the DSM-5.
2. Current diagnosis of bipolar disorder, depression with psychotic features, or depression severe enough to require immediate psychiatric treatment (i.e., serious suicide risk with intent and plan).
3. Unwilling or unable to discontinue current trauma-focused psychotherapy or current substance use psychotherapy.
4. Unstable dose of psychotropic medications in the prior 3 months.
5. Ongoing intimate relationship with the perpetrator of most recent assault.
6. Current diagnosis of a severe substance use disorder according to DSM-5, other than alcohol in the last month.
7. No clear trauma memory.
8. Current higher dose use of benzodiazepines (greater than the equivalent of 4 mg of lorazepam, 2 mg alprazolam, 1.5 mg clonazepam, or 20 mg of diazepam).
D: Inclusion Criteria:

* Identifies as female
* Age \> 18 years
* 2-10 weeks post sexual assault
* PTSD symptoms related to recent sexual assault, specifically defined as a minimum of

  1 reexperiencing, 1 avoidance, 2 negative alterations in mood/cognition, or 2 hyperarousal symptoms
* Drinking more than 3 drinks on one occasion in the last month and at least two reported negative consequences of alcohol use
* Capacity to provide informed consent
* English fluency
* No planned absences that they would be unable to complete 5 weeks of assessments and coaching calls
* Access to a telephone.

Exclusion Criteria:

* Acutely suicidal with intent/plan
* Exhibit current psychosis
* Previous non-response to an adequate trial (8 or more sessions) of Cognitive Processing Therapy (CPT)

Answer: B