Please select the eligibility criteria that correspond to the clinical trial below.
Title: Personalized Exercise for Adolescents With Diabetes
Brief Summary: This study aims to determine the likely benefits of a study that would use the novel techniques both of writing an exercise "prescription" and of including the family and/or community in sticking to the exercise prescription by youths with diabetes, who often suffer eventual cardiovascular complications that might be lessened by the exercise.


Options:
A: Inclusion Criteria:

* child aged between 12.0 and 17.0 years,
* child BMI =/\> 98th percentile,
* first language is English (or fluent in English)
* parent/s willing to participate in the programme with their child
* completion of written informed consent and/or assent prior to any study-specific procedures

Exclusion Criteria:

* severe intellectual difficulties,
* obesity secondary to genetic condition,
* limitations to engaging in physical activity
* use of medication known to effect body weight;
* limitations to using a smartphone device
* known family issues that would affect general compliance and attendance at follow-up visits.
B: Inclusion Criteria:

* Female
* Age 15 to 18
* Presenting to the Gynecology and Adolescent Medicine Clinic for contraception

Exclusion Criteria:

* Prior use of the study medication with no improvement in symptoms
* Any medical condition that indicates continuous OCPs (i.e. acute menorrhagia, dysmenorrhea that did not previously respond to cyclical OCP use)
* Personal history of or current thromboembolic disorder
* First-degree relative(s) with thromboembolic disorder
* Cerebrovascular disease
* Coronary artery disease
* Cardiac valvular disease
* Hypertension (systolic blood pressure \> 160 mmHg or diastolic \> 100 mmHG)
* Diabetes with retinopathy/neuromyopathy/nephropathy)
* Breast cancer
* Endometrial cancer
* Undiagnosed abnormal uterine bleeding
* Cholestatic jaundice of pregnancy
* Hepatic tumor
* Known or suspected pregnancy
* Less than 6 months postpartum if breastfeeding
* Classic migraine with aura or any other neurological signs
* Gallbladder disease
* Taking any medications known to affect the efficacy of OCPs (i.e. phenytoin, phenobarbital, primidone, carbamazepine, griseofulvin, rifampin)
C: Inclusion Criteria:

* Must have a parent or primary caregiver who lives in the same house as the adolescent
* Live within 60 miles of the program's office
* Have at least 3 grandparents who are African American
* Access to the internet
* Children between the ages of 11 and 16
* Child must have BMI above 85th percentile and below 99th percentile
* Have no medical condition that would limit participation in moderate intensity exercise including life-threatening illness (e.g., immobile, severely disabled, or bed ridden)
* Available and able to participate in measures and intervention activities over the next year

Exclusion Criteria:

* Adolescents with chronic illness
* Adolescents who require a specialized diet may not be eligible
* Developmental delay
* Partaking currently in another weight loss program
D: Inclusion Criteria:

* Adolescents aged 12 to 19
* With a diagnosis of type 1 or type 2 DM
* Score on Physical Activity Recall (PAR) Scale of 36 metabolic equivalents (METs) or less to ensure enrollment of youths who are not already engaged in a regular exercise or sports program
* Have a parent (guardian) who also agrees to attend personalized exercise program (PEP) training, participate in exercising and provide ongoing encouragement and support for PEP, and who does not have any positive responses to the Physical Activity Readiness Questionnaire (PAR-Q). The decision to use a value for METs \< 36 is based upon current PAR data from the PI's R01 that revealed a mean score of 34.7 ± 3.1 for teens with type 1 DM and 33.5 ± 1.4 for teens with type 2 DM. Mean scores for both groups reflect activity levels that are well below the current recommendation of 60 minutes of moderate to vigorous exercise on most days of the week.

Exclusion criteria:

Subjects will be excluded if they:

* Are in a school grade that is not appropriate to age within 2 years (this is to control for overt delays in cognition, literacy, and psychological or behavioral functioning)
* Have developed diabetes as a secondary condition to treatment for another chronic condition (i.e., cancer)
* Have known cardiac defects
* Are pregnant females.

Answer: D