Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized, Parallel Group, Double-blind, Multi-center Study Comparing the Efficacy and Safety of AVANDAMET and Metformin After 80 Weeks of Treatment.
Brief Summary: This study will evaluate the longer-term glycemic effect of two medicines approved for initial treatment of type 2 diabetes. The study consists of a 2 week screening period (2 study visits), followed by an 80 week double-blind treatment period (11 study visits). Also, a sub-study was included to look at changes in bone mineral density (BMD) at the lumbar spine.


Options:
A: Arm Label: Metformin; Type: PLACEBO_COMPARATOR; Interventions: Drug: Metformin 500 mg (ttd), Drug: Metformin 1000 mg (ttd), Drug: Metformin 1500 mg (ttd), Drug: Metformin 2000 mg (ttd) | Arm Label: Avandamet (Rosiglitazone maleate/metformin hydrochloride); Type: ACTIVE_COMPARATOR; Interventions: Drug: Avandamet 6 mg/1500 mg (ttd), Drug: Avandamet 4 mg/1000 mg (ttd), Drug: Avandamet 2 mg/500 mg (ttd), Drug: Avandamet 8 mg/ 2000 mg (ttd) | Intervention Type: DRUG; Name: Avandamet 6 mg/1500 mg (ttd); Assigned to Arm(s): Avandamet (Rosiglitazone maleate/metformin hydrochloride) | Intervention Type: DRUG; Name: Avandamet 4 mg/1000 mg (ttd); Assigned to Arm(s): Avandamet (Rosiglitazone maleate/metformin hydrochloride) | Intervention Type: DRUG; Name: Avandamet 2 mg/500 mg (ttd); Assigned to Arm(s): Avandamet (Rosiglitazone maleate/metformin hydrochloride) | Intervention Type: DRUG; Name: Avandamet 8 mg/ 2000 mg (ttd); Assigned to Arm(s): Avandamet (Rosiglitazone maleate/metformin hydrochloride) | Intervention Type: DRUG; Name: Metformin 500 mg (ttd); Assigned to Arm(s): Metformin | Intervention Type: DRUG; Name: Metformin 1000 mg (ttd); Assigned to Arm(s): Metformin | Intervention Type: DRUG; Name: Metformin 1500 mg (ttd); Assigned to Arm(s): Metformin | Intervention Type: DRUG; Name: Metformin 2000 mg (ttd); Assigned to Arm(s): Metformin
B: Arm Label: Saxagliptin and Metformin (A); Type: EXPERIMENTAL; Interventions: Drug: Saxagliptin, Drug: Metformin, Drug: pioglitazone | Arm Label: Saxagliptin and Metformin (B); Type: EXPERIMENTAL; Interventions: Drug: Saxagliptin, Drug: Metformin, Drug: pioglitazone | Arm Label: Saxagliptin and Placebo (C); Type: EXPERIMENTAL; Interventions: Drug: Saxagliptin, Drug: Placebo, Drug: pioglitazone | Arm Label: Metformin and Placebo (D); Type: ACTIVE_COMPARATOR; Interventions: Drug: Metformin, Drug: Placebo, Drug: pioglitazone | Intervention Type: DRUG; Name: Saxagliptin; Assigned to Arm(s): Saxagliptin and Metformin (A), Saxagliptin and Placebo (C) | Intervention Type: DRUG; Name: Saxagliptin; Assigned to Arm(s): Saxagliptin and Metformin (B) | Intervention Type: DRUG; Name: Metformin; Assigned to Arm(s): Metformin and Placebo (D), Saxagliptin and Metformin (A), Saxagliptin and Metformin (B) | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Metformin and Placebo (D), Saxagliptin and Placebo (C) | Intervention Type: DRUG; Name: pioglitazone; Assigned to Arm(s): Metformin and Placebo (D), Saxagliptin and Metformin (A), Saxagliptin and Metformin (B), Saxagliptin and Placebo (C)
C: Arm Label: Metformin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Metformin | Arm Label: Vildagliptin; Type: EXPERIMENTAL; Interventions: Drug: Vildagliptin | Intervention Type: DRUG; Name: Metformin; Assigned to Arm(s): Metformin | Intervention Type: DRUG; Name: Vildagliptin; Assigned to Arm(s): Vildagliptin
D: Intervention Type: DRUG; Name: vildagliptin; Assigned to Arm(s): N/A

Answer: A