Please select the eligibility criteria that correspond to the clinical trial below.
Title: Eeva™ Pregnancy Pilot Study (PPS)
Brief Summary: The purpose of this clinical investigation is to gather pilot data to evaluate the impact of using Eeva™, a time-lapse enabled embryo test, in combination with traditional morphology on clinical pregnancy rates.


Options:
A: Inclusion Criteria:

* Women diagnosed as PCOS according to Chinese PCOS diagnosis criteria;
* Women who have ≥1 years history of infertility;
* Women aged ≥20 and \<35 years old;
* Women with body weight ≥40kg;
* Women who have at least one of the following indications for IVF or ICSI:

  1. Ovulation dysfunction and failed to become pregnant from ovulation induction treatment;
  2. Tubal factors: unilateral or bilateral tubal obstruction, adhesion, unilateral or bilateral Salpingectomy or tubal ligation;
  3. Male factors: oligoasthenozoospermia, obstructive azoospermia;
* Women who are undergoing their first cycle of IVF or ICSI;
* Women who retrieved oocytes number \> 3;
* Women who are capable of giving informed consent.

Exclusion Criteria:

* Women who underwent unilateral ovariectomy;
* Women diagnosed as uterus abnormality: malformed uterus (uterus unicorns, septate uterus, duplex uterus, uterus bicomis), adenomyosis, submucous myoma, intrauterine adhesion;
* Women or their partner with abnormal chromosome karyotype including chromosome polymorphism;
* Women who have experienced recurrent spontaneous abortion (including biochemical pregnancy abortion) more than 2 times;
* Women with medical condition that represent contraindication to assisted reproductive technology and/or pregnancy;
* Women who has developed severe OHSS before oocyte pick-up day;
* Women with retrieved oocytes number ≤3;
* Women who are unable to comply with the study procedures.
B: Inclusion Criteria:

* Women undergoing fresh in vitro fertilization treatment using their own eggs
* ≤ 40 years
* ≥ 4 diploid embryos (i.e. having 2 PNs)
* ≤ 3 Prior ART cycles (IVF, ICSI and related procedures)
* All 2PN embryos (for all 3 arms) must be imaged by Eeva
* Subject willing to comply with study protocol and procedures
* Subject willing to provide written informed consent

Exclusion Criteria:

* Preimplantation genetic diagnosis or preimplantation genetic screening
* Planned "freeze all" cycle (eggs or embryos)
* Asherman's Syndrome
* Donor egg
* Gestational carrier
* Presence of Hydrosalpinx on ultrasound
* Concurrent participation in an interventional clinical study
C: Inclusion Criteria:

* Women under 42 years of age
* Presence of at least 3 embryos suitable to freeze on day 2 or 3 following fertilisation based on the centre's criteria
* Written informed consent

Exclusion Criteria:

* Women using donor eggs/donor sperm
* Women undergoing preimplantation genetic diagnosis
* Women with abnormal uterine cavity shown on hysterosalpingogram or saline infusion sonogram
* Women with hydrosalpinges shown on scanning and not corrected treated
* Women with excessive ovarian response at risk of ovarian hyperstimulation where elective freeze is already planned
* Women with serum progesterone level on day of human chorionic gonadotrophin\>1.5ng/ml or 5 nmol/L
* Women whose embryos have not survived freeze-thawing in the past
* Fresh transfer is planned e.g. patients with endometriosis or adenomyosis who have received prolonged downregulation
* Only frozen transfer is planned e.g. patients receiving ovarian stimulation regimens which may have adverse impacts on the endometrium
D: Inclusion Criteria:

* First or second IVF/ICSI cycle
* High response to ovarian stimulation (defined as presence of ≥18 follicles of ≥11 mm on the day of GnRH triggering)
* GnRH antagonist down-regulation
* Signed informed consent
* Patients can be included only once in the trial
* Planned replacement of 1 or 2 blastocysts

Exclusion Criteria:

* Other known reasons for impaired implantation (i.e. hydrosalpinx, fibroid distorting the endometrial cavity, Asherman's syndrome, thrombophilia or endometrial tuberculosis)
* Oocyte/embryos donation acceptors
* Embryos planned to undergo preimplantation genetic diagnosis/screening
* Body mass index ≥35 or ≤18
* Women who have previously enrolled in the trial
* Those unable to comprehend the investigational nature of the proposed study

Answer: B