TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Prospective, Randomized, Controlled Clinical Trial Evaluating the Superiority of Preimplantation Genetic Screening (PGS) and Deferred Transfer of Cryopreserved Embryos Over "Freeze-Only" Deferred Transfer Without PGS or Immediate Embryo Transfer During a "Fresh" In Vitro Fertilization Cycle
Brief Summary: The trial objective is to determine whether the deferred transfer of embryos following cryopreservation at the blastocyst stage following pre-implantation genetic screening (PGS-FET) improves live birthrates compared to both the deferred transfer of cryopreserved embryos without PGS (FET) and immediate transfer at the conclusion of a "fresh" in vitro fertilization (IVF) cycle (Fresh). Additionally, whether "freeze-only" (FET) improves live birth rates compared to "fresh" will be determined.


Options:
A: Arm Label: Group A; Type: EXPERIMENTAL; Interventions: Other: PGS | Arm Label: Group B; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: PGS; Assigned to Arm(s): Group A
B: Arm Label: PGS group; Type: ACTIVE_COMPARATOR; Interventions: Procedure: blastocyst morphologic score, Procedure: blastocyst biopsy and sequencing, Procedure: freeze-all and single thawed blastocyst transfer | Arm Label: IVF group; Type: ACTIVE_COMPARATOR; Interventions: Procedure: blastocyst morphologic score, Procedure: freeze-all and single thawed blastocyst transfer | Intervention Type: PROCEDURE; Name: blastocyst morphologic score; Assigned to Arm(s): IVF group, PGS group | Intervention Type: PROCEDURE; Name: blastocyst biopsy and sequencing; Assigned to Arm(s): PGS group | Intervention Type: PROCEDURE; Name: freeze-all and single thawed blastocyst transfer; Assigned to Arm(s): IVF group, PGS group
C: Arm Label: PGS-FET; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Trophectoderm biopsy, Procedure: Cryopreservation, Procedure: Embryo Transfer | Arm Label: FET; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Cryopreservation, Procedure: Embryo Transfer | Arm Label: Fresh; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Embryo Transfer | Intervention Type: PROCEDURE; Name: Trophectoderm biopsy; Assigned to Arm(s): PGS-FET | Intervention Type: PROCEDURE; Name: Cryopreservation; Assigned to Arm(s): FET, PGS-FET | Intervention Type: PROCEDURE; Name: Embryo Transfer; Assigned to Arm(s): FET, Fresh, PGS-FET
D: Arm Label: local ingury; Type: ACTIVE_COMPARATOR; Interventions: Procedure: local injury | Arm Label: control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: PROCEDURE; Name: local injury; Assigned to Arm(s): local ingury

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The CHRONICLE Study: A Longitudinal Prospective Observational Study of the Characteristics, Treatment Patterns and Health Outcomes of Individuals With Severe Asthma in the United States
Brief Summary: The CHRONICLE Study is a multi-center, non-interventional, prospective cohort study of adults with severe asthma who do not achieve control with high-dose inhaled corticosteroid (ICS) therapy with additional controllers and/or require systemic corticosteroid or monoclonal antibody therapy. Data will be collected from the healthcare provider in a uniform manner for every patient enrolled using an electronic case report form (eCRF). Data will be collected monthly from patients via web-based surveys. Patients will be followed until study discontinuation or the patient withdraws from the study or death, whichever occurs first. The expectation is that patients will be followed for a period of at least 3 years.


Options:
A: Arm Label: OAT + Omalizumab; Type: EXPERIMENTAL; Interventions: Drug: Omalizumab, Other: Optimized asthma therapy | Arm Label: Optimized Asthma Treatment (OAT); Type: ACTIVE_COMPARATOR; Interventions: Other: Optimized asthma therapy | Intervention Type: DRUG; Name: Omalizumab; Assigned to Arm(s): OAT + Omalizumab | Intervention Type: OTHER; Name: Optimized asthma therapy; Assigned to Arm(s): OAT + Omalizumab, Optimized Asthma Treatment (OAT)
B: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: Active; Type: ACTIVE_COMPARATOR; Interventions: Drug: GSK679586 | Intervention Type: DRUG; Name: GSK679586; Assigned to Arm(s): Active | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
C: Arm Label: Cohort of US adults with severe asthma; Type: N/A; Interventions: N/A
D: Arm Label: Benralizumab 30 mg q.4 weeks; Type: EXPERIMENTAL; Interventions: Biological: Benralizumab | Arm Label: Benralizumab 30 mg q.8 weeks; Type: EXPERIMENTAL; Interventions: Biological: Benralizumab | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Biological: Placebo | Intervention Type: BIOLOGICAL; Name: Benralizumab; Assigned to Arm(s): Benralizumab 30 mg q.4 weeks, Benralizumab 30 mg q.8 weeks | Intervention Type: BIOLOGICAL; Name: Placebo; Assigned to Arm(s): Placebo

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomised Controlled Trial of the Effect of Dietary Salt Reduction on Blood Pressure and Other Cardiovascular Parameters in Kidney Transplant Recipients
Brief Summary: Cardiovascular morbidity and mortality is increased in kidney transplant patients. High blood pressure (BP) contributes significantly to this risk and is also associated with shortened allograft survival. Salt reduction lowers BP in the general population and there is emerging data that salt reduction also effectively lowers BP in chronic kidney disease (CKD). Kidney transplant patients, by definition have CKD, but they differ fundamentally from the general CKD population in that they are on medications which can predispose to high blood pressure, their kidneys are denervated, and they often have reasonable excretory kidney function.

The proposed study will be an eight-week randomised, controlled trial assessing the effect of intensive dietary salt advice on cardiovascular risk factors in kidney transplant patients. The primary outcome is office BP readings, with the effect on 24-hour ambulatory blood pressure, proteinuria, arterial stiffness and endothelial function being studied as secondary outcomes.


Options:
A: Arm Label: Diuretic treatment; Type: ACTIVE_COMPARATOR; Interventions: Drug: Amiloride, Drug: Hydrochlorothiazide | Arm Label: Low-sodium diet; Type: ACTIVE_COMPARATOR; Interventions: Other: Low-sodium diet | Intervention Type: DRUG; Name: Amiloride; Assigned to Arm(s): Diuretic treatment | Intervention Type: DRUG; Name: Hydrochlorothiazide; Assigned to Arm(s): Diuretic treatment | Intervention Type: OTHER; Name: Low-sodium diet; Assigned to Arm(s): Low-sodium diet
B: Arm Label: Sequence: ABBA A=usual care, B=self-care; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Self-care management program | Arm Label: Sequence BAAB; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Self-care management program | Arm Label: Sequence AABB; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Self-care management program | Arm Label: Sequence BBAA; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Self-care management program | Intervention Type: BEHAVIORAL; Name: Self-care management program; Assigned to Arm(s): Sequence AABB, Sequence BAAB, Sequence BBAA, Sequence: ABBA A=usual care, B=self-care
C: Intervention Type: DRUG; Name: Slow Sodium; Assigned to Arm(s): N/A
D: Arm Label: Low Salt Diet; Type: EXPERIMENTAL; Interventions: Other: Dietary salt reduction | Arm Label: Standard Treatment; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Dietary salt reduction; Assigned to Arm(s): Low Salt Diet

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effects of Inspiratory Muscle Training on Postural Stability, Balance, Pulmonary Function and Functional Capacity in Children With Cystic Fibrosis
Brief Summary: It is extensively reported in the literature that patients with chronic obstructive lung disease may have impairments in balance and postural control which further increase the disease burden. Mechanisms related to these impairments include, but are not limited to increased work of breathing, diaphragm weakness, peripheral muscle weakness and systemic inflammation. Since the similar symptoms are reported for the children with cystic fibrosis, it is hypothesized that balance and postural control may also be compromised in these patients. Inspiratory muscle training (IMT) is shown to improve diaphragm strength and pulmonary function. Considering the relation between diaphragm which is one of the core muscles, and balance, IMT may also have an impact on postural control and balance alongside the standard clinical parameters such as respiratory muscle strength, pulmonary function and functional capacity in these patients. Thus, the aim of this study was to investigate the effects of inspiratory muscle training and conventional chest physiotherapy on postural stability, balance, pulmonary function and functional capacity in children with cystic fibrosis.


Options:
A: Arm Label: Control Group; Type: ACTIVE_COMPARATOR; Interventions: Other: Conventional chest physiotherapy | Arm Label: Training Group; Type: EXPERIMENTAL; Interventions: Other: Conventional chest physiotherapy, Other: Inspiratory muscle training | Intervention Type: OTHER; Name: Conventional chest physiotherapy; Assigned to Arm(s): Control Group, Training Group | Intervention Type: OTHER; Name: Inspiratory muscle training; Assigned to Arm(s): Training Group
B: Arm Label: Exercise Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise Intervention | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Exercise Intervention; Assigned to Arm(s): Exercise Intervention
C: Arm Label: GExp; Type: EXPERIMENTAL; Interventions: Device: Inspiratory muscle training | Arm Label: GCon; Type: ACTIVE_COMPARATOR; Interventions: Device: Inspiratory muscle training | Intervention Type: DEVICE; Name: Inspiratory muscle training; Assigned to Arm(s): GCon, GExp
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Physical activity | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Wellness | Intervention Type: BEHAVIORAL; Name: Physical activity; Assigned to Arm(s): 1 | Intervention Type: BEHAVIORAL; Name: Wellness; Assigned to Arm(s): 2

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Interest of Oxygenated Hypothermic Perfusion in Preservation of Hepatic Grafts From Expanded Criteria Donors. A Prospective Monocentric Study.
Brief Summary: Interest of oxygenated hypothermic perfusion in preservation of hepatic grafts from expanded criteria donors.


Options:
A: Arm Label: Kidney transplants; Type: N/A; Interventions: N/A | Arm Label: Liver transplants; Type: N/A; Interventions: N/A | Arm Label: Heart transplants; Type: N/A; Interventions: N/A | Arm Label: Lung transplants; Type: N/A; Interventions: N/A
B: Arm Label: Hypothermic oxygenated perfusion (HOPE); Type: EXPERIMENTAL; Interventions: Device: Hypothermic oxygenated perfusion (HOPE) | Arm Label: Conventional cold storage (CCS); Type: ACTIVE_COMPARATOR; Interventions: Procedure: Conventional cold storage (CCS) | Intervention Type: DEVICE; Name: Hypothermic oxygenated perfusion (HOPE); Assigned to Arm(s): Hypothermic oxygenated perfusion (HOPE) | Intervention Type: PROCEDURE; Name: Conventional cold storage (CCS); Assigned to Arm(s): Conventional cold storage (CCS)
C: Arm Label: Dual hypothermic oxygenated perfusion; Type: EXPERIMENTAL; Interventions: Procedure: Dual hypothermic oxygenated perfusion, Device: Liver Assist®, Procedure: Perfusion fluid, Drug: Glutathione | Arm Label: Care as usual; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: PROCEDURE; Name: Dual hypothermic oxygenated perfusion; Assigned to Arm(s): Dual hypothermic oxygenated perfusion | Intervention Type: DEVICE; Name: Liver Assist®; Assigned to Arm(s): Dual hypothermic oxygenated perfusion | Intervention Type: PROCEDURE; Name: Perfusion fluid; Assigned to Arm(s): Dual hypothermic oxygenated perfusion | Intervention Type: DRUG; Name: Glutathione; Assigned to Arm(s): Dual hypothermic oxygenated perfusion
D: Arm Label: Hypothermic oxygenated perfusion (HOPE); Type: EXPERIMENTAL; Interventions: Device: Hypothermic oxygenated perfusion (HOPE) | Arm Label: Conventional cold storage; Type: ACTIVE_COMPARATOR; Interventions: Other: Conventional cold storage | Intervention Type: DEVICE; Name: Hypothermic oxygenated perfusion (HOPE); Assigned to Arm(s): Hypothermic oxygenated perfusion (HOPE) | Intervention Type: OTHER; Name: Conventional cold storage; Assigned to Arm(s): Conventional cold storage

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Effect of a Brief Psychological Intervention on Reducing Self-harm Repetition: Feasibility Study
Brief Summary: Recent research has focused on examining brief interventions for reducing self-harm, such as the volitional help sheet (VHS). The VHS is a theory-based psychological intervention. Two previous studies applying this tool for reducing self-harm repetition showed inconsistent results; one showed reduced subsequent self-reported suicidal ideation and behavior in patients presenting to hospital for self-harm, whilst the other showed no effect on the number of patients who re-presented to hospital with self-harm. The aim of this study is to investigate the feasibility of the VHS intervention amongst self-harm patients in Taiwan and explore its effect on self-harm repetition based on self-reported self-harm, hospital re-presentations with self-harm, and self-harm episodes from a nationwide self-harm registry. It is a two-phase study: first a qualitative study and second an exploratory randomized control trial. The first study is to interview people who self-harm about their perceptions about the VHS on the online platform, to inform the modification of VHS and the best way to intervene. The second is to examine the feasibility and effect of this intervention at the emergency department setting.


Options:
A: Arm Label: Intensive Group Analytic Psychotherapy; Type: EXPERIMENTAL; Interventions: Behavioral: Intensive Group Analytic Psychotherapy | Arm Label: Intensive GCBT; Type: EXPERIMENTAL; Interventions: Behavioral: Intensive transdiagnostic cognitive-behavioral group therapy | Arm Label: Wait-list control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Intensive Group Analytic Psychotherapy; Assigned to Arm(s): Intensive Group Analytic Psychotherapy | Intervention Type: BEHAVIORAL; Name: Intensive transdiagnostic cognitive-behavioral group therapy; Assigned to Arm(s): Intensive GCBT
B: Arm Label: VHS group; Type: EXPERIMENTAL; Interventions: Behavioral: the volitional help sheet | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: the volitional help sheet; Assigned to Arm(s): VHS group
C: Arm Label: Mentalization Based Treatment; Type: EXPERIMENTAL; Interventions: Behavioral: Mentalization Based Treatment | Arm Label: Treatment As Usual; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Treatment As Usual | Intervention Type: BEHAVIORAL; Name: Mentalization Based Treatment; Assigned to Arm(s): Mentalization Based Treatment | Intervention Type: BEHAVIORAL; Name: Treatment As Usual; Assigned to Arm(s): Treatment As Usual
D: Arm Label: cognitive remediation; Type: EXPERIMENTAL; Interventions: Other: cognitive remediation | Arm Label: Psychoeducation; Type: ACTIVE_COMPARATOR; Interventions: Other: Psychoeducation | Intervention Type: OTHER; Name: cognitive remediation; Assigned to Arm(s): cognitive remediation | Intervention Type: OTHER; Name: Psychoeducation; Assigned to Arm(s): Psychoeducation

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Effect of a Brief Psychological Intervention on Reducing Self-harm Repetition: Feasibility Study
Brief Summary: Recent research has focused on examining brief interventions for reducing self-harm, such as the volitional help sheet (VHS). The VHS is a theory-based psychological intervention. Two previous studies applying this tool for reducing self-harm repetition showed inconsistent results; one showed reduced subsequent self-reported suicidal ideation and behavior in patients presenting to hospital for self-harm, whilst the other showed no effect on the number of patients who re-presented to hospital with self-harm. The aim of this study is to investigate the feasibility of the VHS intervention amongst self-harm patients in Taiwan and explore its effect on self-harm repetition based on self-reported self-harm, hospital re-presentations with self-harm, and self-harm episodes from a nationwide self-harm registry. It is a two-phase study: first a qualitative study and second an exploratory randomized control trial. The first study is to interview people who self-harm about their perceptions about the VHS on the online platform, to inform the modification of VHS and the best way to intervene. The second is to examine the feasibility and effect of this intervention at the emergency department setting.


Options:
A: Arm Label: Control (volitional help sheet); Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Volitional help sheet | Arm Label: Intervention (volitional help sheet); Type: EXPERIMENTAL; Interventions: Behavioral: Volitional help sheet | Intervention Type: BEHAVIORAL; Name: Volitional help sheet; Assigned to Arm(s): Control (volitional help sheet) | Intervention Type: BEHAVIORAL; Name: Volitional help sheet; Assigned to Arm(s): Intervention (volitional help sheet)
B: Arm Label: VHS group; Type: EXPERIMENTAL; Interventions: Behavioral: the volitional help sheet | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: the volitional help sheet; Assigned to Arm(s): VHS group
C: Arm Label: TAU w/ mobile app + volunteer support; Type: EXPERIMENTAL; Interventions: Behavioral: Volunteer support, Other: Mobile app | Arm Label: TAU w/ mobile app engagement; Type: EXPERIMENTAL; Interventions: Other: Mobile app | Arm Label: Treatment as Usual (TAU); Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Volunteer support; Assigned to Arm(s): TAU w/ mobile app + volunteer support | Intervention Type: OTHER; Name: Mobile app; Assigned to Arm(s): TAU w/ mobile app + volunteer support, TAU w/ mobile app engagement
D: Arm Label: ASSIP + TAU goup; Type: EXPERIMENTAL; Interventions: Other: ASSIP | Arm Label: TAU; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: ASSIP; Assigned to Arm(s): ASSIP + TAU goup

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Effect of a Brief Psychological Intervention on Reducing Self-harm Repetition: Feasibility Study
Brief Summary: Recent research has focused on examining brief interventions for reducing self-harm, such as the volitional help sheet (VHS). The VHS is a theory-based psychological intervention. Two previous studies applying this tool for reducing self-harm repetition showed inconsistent results; one showed reduced subsequent self-reported suicidal ideation and behavior in patients presenting to hospital for self-harm, whilst the other showed no effect on the number of patients who re-presented to hospital with self-harm. The aim of this study is to investigate the feasibility of the VHS intervention amongst self-harm patients in Taiwan and explore its effect on self-harm repetition based on self-reported self-harm, hospital re-presentations with self-harm, and self-harm episodes from a nationwide self-harm registry. It is a two-phase study: first a qualitative study and second an exploratory randomized control trial. The first study is to interview people who self-harm about their perceptions about the VHS on the online platform, to inform the modification of VHS and the best way to intervene. The second is to examine the feasibility and effect of this intervention at the emergency department setting.


Options:
A: Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Active group; Type: EXPERIMENTAL; Interventions: Behavioral: Psychotherapy | Intervention Type: BEHAVIORAL; Name: Psychotherapy; Assigned to Arm(s): Active group
B: Arm Label: Youth-Nominated Support Team; Type: EXPERIMENTAL; Interventions: Behavioral: Youth-Nominated Support Team | Arm Label: Enhanced Treatment as Usual; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Youth-Nominated Support Team; Assigned to Arm(s): Youth-Nominated Support Team
C: Arm Label: VHS group; Type: EXPERIMENTAL; Interventions: Behavioral: the volitional help sheet | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: the volitional help sheet; Assigned to Arm(s): VHS group
D: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: General Psychiatric Management | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Behavioral: Dialectical Behaviour Therapy | Intervention Type: BEHAVIORAL; Name: General Psychiatric Management; Assigned to Arm(s): A | Intervention Type: BEHAVIORAL; Name: Dialectical Behaviour Therapy; Assigned to Arm(s): 2

Answer: C