Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase III, Randomized, Placebo-Controlled Clinical Trial to Study the Efficacy and Safety of MK-3641, a Ragweed (Ambrosia Artemisiifolia) Sublingual Immunotherapy Tablet, in Children With a History of Ragweed-Induced Rhinoconjunctivitis With or Without Asthma
Brief Summary: The purpose of this study is to assess the efficacy and safety of short ragweed pollen allergen extract (MK-3641, SCH 039641, RAGWITEK™) sublingual immunotherapy tablets in children aged 5 to 17 years with ragweed-induced allergic rhinitis/rhinoconjunctivitis with or without asthma. The primary hypothesis of this study is that administration of short ragweed pollen allergen extract sublingual immunotherapy tablets to children 5 to 17 years of age, compared with placebo, will result in a significant reduction in the combination of rhinoconjunctivitis symptoms and medication use over the peak ragweed season (RS).


Options:
A: Arm Label: Short ragweed pollen allergen extract; Type: EXPERIMENTAL; Interventions: Biological: Short ragweed pollen allergen extract, Drug: Self-injectable epinephrine, Drug: Albuterol/Salbutamol, Drug: Loratadine, Drug: Olopatadine, Drug: Mometasone furoate monohydrate | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Biological: Placebo, Drug: Self-injectable epinephrine, Drug: Albuterol/Salbutamol, Drug: Loratadine, Drug: Olopatadine, Drug: Mometasone furoate monohydrate | Intervention Type: BIOLOGICAL; Name: Short ragweed pollen allergen extract; Assigned to Arm(s): Short ragweed pollen allergen extract | Intervention Type: BIOLOGICAL; Name: Placebo; Assigned to Arm(s): Placebo | Intervention Type: DRUG; Name: Self-injectable epinephrine; Assigned to Arm(s): Placebo, Short ragweed pollen allergen extract | Intervention Type: DRUG; Name: Albuterol/Salbutamol; Assigned to Arm(s): Placebo, Short ragweed pollen allergen extract | Intervention Type: DRUG; Name: Loratadine; Assigned to Arm(s): Placebo, Short ragweed pollen allergen extract | Intervention Type: DRUG; Name: Olopatadine; Assigned to Arm(s): Placebo, Short ragweed pollen allergen extract | Intervention Type: DRUG; Name: Mometasone furoate monohydrate; Assigned to Arm(s): Placebo, Short ragweed pollen allergen extract
B: Arm Label: Immunotherapy; Type: EXPERIMENTAL; Interventions: Biological: Grass pollen allergens in a water/glycerol solution | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: BIOLOGICAL; Name: Grass pollen allergens in a water/glycerol solution; Assigned to Arm(s): Immunotherapy | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
C: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: Grazax | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Drug: Grazax | Intervention Type: DRUG; Name: Grazax; Assigned to Arm(s): 1, 2
D: Arm Label: MK-8237; Type: EXPERIMENTAL; Interventions: Biological: MK-8237 tablets, Drug: Rescue Medication: Self-Injectable Epinephrine, Drug: Rescue Medication: Loratadine tablets, Drug: Rescue Medication: Olopatadine ophthalmic drops, Drug: Rescue Medication: Mometasone furoate nasal spray | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Biological: Placebo tablets, Drug: Rescue Medication: Self-Injectable Epinephrine, Drug: Rescue Medication: Loratadine tablets, Drug: Rescue Medication: Olopatadine ophthalmic drops, Drug: Rescue Medication: Mometasone furoate nasal spray | Intervention Type: BIOLOGICAL; Name: MK-8237 tablets; Assigned to Arm(s): MK-8237 | Intervention Type: BIOLOGICAL; Name: Placebo tablets; Assigned to Arm(s): Placebo | Intervention Type: DRUG; Name: Rescue Medication: Self-Injectable Epinephrine; Assigned to Arm(s): MK-8237, Placebo | Intervention Type: DRUG; Name: Rescue Medication: Loratadine tablets; Assigned to Arm(s): MK-8237, Placebo | Intervention Type: DRUG; Name: Rescue Medication: Olopatadine ophthalmic drops; Assigned to Arm(s): MK-8237, Placebo | Intervention Type: DRUG; Name: Rescue Medication: Mometasone furoate nasal spray; Assigned to Arm(s): MK-8237, Placebo

Answer: A