Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized Phase III Post-operative Trial of Platinum Based Chemotherapy vs. Capecitabine in Patients With Residual Triple-Negative Basal-Like Breast Cancer Following Neoadjuvant Chemotherapy
Brief Summary: This randomized phase III trial studies how well cisplatin or carboplatin (platinum based chemotherapy) works compared to capecitabine in treating patients with remaining (residual) basal-like triple-negative breast cancer following chemotherapy after surgery (neoadjuvant). Drugs used in chemotherapy, such as cisplatin, carboplatin and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether cisplatin or carboplatin is more effective than capecitabine in treating patients with residual triple negative basal-like breast cancer.


Options:
A: Arm Label: Arm A (observation) (closed to accrual 05/16/2016); Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Arm B (cisplatin or carboplatin); Type: EXPERIMENTAL; Interventions: Drug: Carboplatin, Drug: Cisplatin | Arm Label: Arm C (capecitabine); Type: ACTIVE_COMPARATOR; Interventions: Drug: Capecitabine | Intervention Type: DRUG; Name: Capecitabine; Assigned to Arm(s): Arm C (capecitabine) | Intervention Type: DRUG; Name: Carboplatin; Assigned to Arm(s): Arm B (cisplatin or carboplatin) | Intervention Type: DRUG; Name: Cisplatin; Assigned to Arm(s): Arm B (cisplatin or carboplatin)
B: Arm Label: Arm A; Type: EXPERIMENTAL; Interventions: Drug: Trastuzumab, Drug: Pertuzumab | Arm Label: Arm B; Type: ACTIVE_COMPARATOR; Interventions: Drug: Trastuzumab, Drug: Pertuzumab, Drug: Paclitaxel | Intervention Type: DRUG; Name: Trastuzumab; Assigned to Arm(s): Arm A, Arm B | Intervention Type: DRUG; Name: Pertuzumab; Assigned to Arm(s): Arm A, Arm B | Intervention Type: DRUG; Name: Paclitaxel; Assigned to Arm(s): Arm B
C: Arm Label: Pembrolizumab + Chemotherapy; Type: EXPERIMENTAL; Interventions: Biological: Pembrolizumab, Drug: Carboplatin, Drug: Paclitaxel, Drug: Doxorubicin, Drug: Epirubicin, Drug: Cyclophosphamide, Biological: Granulocyte colony stimulating factor: Filgrastim or Pegfilgastrim | Arm Label: Placebo + Chemotherapy; Type: ACTIVE_COMPARATOR; Interventions: Drug: Carboplatin, Drug: Paclitaxel, Drug: Doxorubicin, Drug: Epirubicin, Drug: Cyclophosphamide, Drug: Placebo, Biological: Granulocyte colony stimulating factor: Filgrastim or Pegfilgastrim | Intervention Type: BIOLOGICAL; Name: Pembrolizumab; Assigned to Arm(s): Pembrolizumab + Chemotherapy | Intervention Type: DRUG; Name: Carboplatin; Assigned to Arm(s): Pembrolizumab + Chemotherapy, Placebo + Chemotherapy | Intervention Type: DRUG; Name: Paclitaxel; Assigned to Arm(s): Pembrolizumab + Chemotherapy, Placebo + Chemotherapy | Intervention Type: DRUG; Name: Doxorubicin; Assigned to Arm(s): Pembrolizumab + Chemotherapy, Placebo + Chemotherapy | Intervention Type: DRUG; Name: Epirubicin; Assigned to Arm(s): Pembrolizumab + Chemotherapy, Placebo + Chemotherapy | Intervention Type: DRUG; Name: Cyclophosphamide; Assigned to Arm(s): Pembrolizumab + Chemotherapy, Placebo + Chemotherapy | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo + Chemotherapy | Intervention Type: BIOLOGICAL; Name: Granulocyte colony stimulating factor: Filgrastim or Pegfilgastrim; Assigned to Arm(s): Pembrolizumab + Chemotherapy, Placebo + Chemotherapy
D: Arm Label: Arm A; Type: ACTIVE_COMPARATOR; Interventions: Drug: Cyclophosphamide, Drug: Doxorubicin, Drug: Paclitaxel, Drug: Carboplatin, Drug: Veliparib | Arm Label: Arm C; Type: PLACEBO_COMPARATOR; Interventions: Drug: Cyclophosphamide, Drug: Placebo, Drug: Doxorubicin, Drug: Paclitaxel | Arm Label: Arm B; Type: PLACEBO_COMPARATOR; Interventions: Drug: Cyclophosphamide, Drug: Doxorubicin, Drug: Paclitaxel, Drug: Carboplatin, Drug: Placebo | Intervention Type: DRUG; Name: Cyclophosphamide; Assigned to Arm(s): Arm A, Arm B, Arm C | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Arm C | Intervention Type: DRUG; Name: Doxorubicin; Assigned to Arm(s): Arm A, Arm B, Arm C | Intervention Type: DRUG; Name: Paclitaxel; Assigned to Arm(s): Arm A, Arm B, Arm C | Intervention Type: DRUG; Name: Carboplatin; Assigned to Arm(s): Arm A, Arm B | Intervention Type: DRUG; Name: Veliparib; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Arm B, Arm C

Answer: A