TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized, Open Label, Single-Dose, 2-Way Cross-over Clinical Trial to Compare the Safety and Pharmacokinetic Characteristics of Combination of Rosuvastatin and CS-866 and DWJ1276 in Healthy Male Volunteers
Brief Summary: This study investigates safety and pharmacokinetic comparison of DWJ1276, a combination drug of Rosuvastatin and Olmesartan (test formulation), and co-administration of Rosuvastatin and Olmesartan (reference formulation) for single dose in healthy volunteers


Options:
A: Arm Label: Caduet; Type: EXPERIMENTAL; Interventions: Drug: Amlodipine besylate/atorvastatin calcium single pill combination | Intervention Type: DRUG; Name: Amlodipine besylate/atorvastatin calcium single pill combination; Assigned to Arm(s): Caduet
B: Arm Label: Test and reference formulations; Type: EXPERIMENTAL; Interventions: Drug: Test formulation, Drug: Reference formulation | Intervention Type: DRUG; Name: Test formulation; Assigned to Arm(s): Test and reference formulations | Intervention Type: DRUG; Name: Reference formulation; Assigned to Arm(s): Test and reference formulations
C: Arm Label: FDC Fixed Dose Combination; Type: EXPERIMENTAL; Interventions: Drug: FDC | Arm Label: Conventional treatment; Type: ACTIVE_COMPARATOR; Interventions: Drug: Separately drugs, simvastatin, aspirin and ramipril | Intervention Type: DRUG; Name: FDC; Assigned to Arm(s): FDC Fixed Dose Combination | Intervention Type: DRUG; Name: Separately drugs, simvastatin, aspirin and ramipril; Assigned to Arm(s): Conventional treatment
D: Arm Label: polypill; Type: EXPERIMENTAL; Interventions: Drug: polypill | Arm Label: Usual Care; Type: ACTIVE_COMPARATOR; Interventions: Drug: Usual cardiovascular medications | Intervention Type: DRUG; Name: polypill; Assigned to Arm(s): polypill | Intervention Type: DRUG; Name: Usual cardiovascular medications; Assigned to Arm(s): Usual Care

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized Controlled Trial Comparing Post-operative Pain in Single-incision Laparoscopic Cholecystectomy Versus Conventional Laparoscopic Cholecystectomy
Brief Summary: This study aims to evaluate post-operative pain in single-incision laparoscopic cholecystectomy (SILC) versus the conventional four port technique (LC). The investigators hypothesize that SILC is non-inferior in post-operative pain.


Options:
A: Arm Label: SILC; Type: EXPERIMENTAL; Interventions: Procedure: SILC | Arm Label: LC; Type: ACTIVE_COMPARATOR; Interventions: Procedure: LC | Intervention Type: PROCEDURE; Name: SILC; Assigned to Arm(s): SILC | Intervention Type: PROCEDURE; Name: LC; Assigned to Arm(s): LC
B: Arm Label: Veress needle technique; Type: OTHER; Interventions: Procedure: Laparoscopy | Arm Label: Direct trocar technique; Type: OTHER; Interventions: Procedure: Laparoscopy | Arm Label: Open technique; Type: OTHER; Interventions: Procedure: laparoscopy | Intervention Type: PROCEDURE; Name: laparoscopy; Assigned to Arm(s): Open technique | Intervention Type: PROCEDURE; Name: Laparoscopy; Assigned to Arm(s): Veress needle technique | Intervention Type: PROCEDURE; Name: Laparoscopy; Assigned to Arm(s): Direct trocar technique | Intervention Type: PROCEDURE; Name: Laparoscopy; Assigned to Arm(s): Open technique
C: Arm Label: Group 1; Type: ACTIVE_COMPARATOR; Interventions: Procedure: SILS cholecystectomy | Arm Label: Group 2; Type: ACTIVE_COMPARATOR; Interventions: Procedure: TPCL cholecystectomy | Intervention Type: PROCEDURE; Name: SILS cholecystectomy; Assigned to Arm(s): Group 1 | Intervention Type: PROCEDURE; Name: TPCL cholecystectomy; Assigned to Arm(s): Group 2
D: Arm Label: SILS appendectomy; Type: EXPERIMENTAL; Interventions: Procedure: SILS appendectomy | Arm Label: Conventional laparoscopic appendectomy; Type: ACTIVE_COMPARATOR; Interventions: Procedure: conventional laparoscopic appendectomy | Intervention Type: PROCEDURE; Name: SILS appendectomy; Assigned to Arm(s): SILS appendectomy | Intervention Type: PROCEDURE; Name: conventional laparoscopic appendectomy; Assigned to Arm(s): Conventional laparoscopic appendectomy

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: NPB-01(Intravenous Immunoglobulin) Maintenance Therapy for Patients With Chronic Inflammatory Demyelinating Polyneuropathy.
Brief Summary: Patients diagnosed with Chronic Inflammatory Demyelinating Polyneuropathy were confirmed based on the European Federation of Neurological Societies/ Peripheral. Nerve Society Guideline. Patients who meet all inclusion criteria and do not conflict with the exclusion criteria will receive NPB-01 (intravenous immunoglobulin) 400mg/kg/day for five consecutive days. Subsequently, patients receive NPB-01 1g/kg every 3weeks and evaluate the Inflammatory Neuropathy Cause and Treatment（INCAT） score and INCAT sensory sumscore（ISS） et al.

As a safety endpoint, the safety of NPB-01 will be investigated the occurrence of adverse events by one year after the start of the study treatment.


Options:
A: Arm Label: 0.5 g/kg NewGam; Type: EXPERIMENTAL; Interventions: Drug: NewGam | Arm Label: 1.0 g/kg NewGam; Type: EXPERIMENTAL; Interventions: Drug: NewGam | Arm Label: 2.0 g/kg NewGam; Type: EXPERIMENTAL; Interventions: Drug: NewGam | Intervention Type: DRUG; Name: NewGam; Assigned to Arm(s): 0.5 g/kg NewGam, 1.0 g/kg NewGam, 2.0 g/kg NewGam
B: Arm Label: IgPro20 low dose; Type: EXPERIMENTAL; Interventions: Biological: IgPro20 (low dose), Biological: IgPro10 | Arm Label: IgPro20 high dose; Type: EXPERIMENTAL; Interventions: Biological: IgPro10, Biological: IgPro20 (high dose) | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Biological: Placebo, Biological: IgPro10 | Intervention Type: BIOLOGICAL; Name: IgPro20 (low dose); Assigned to Arm(s): IgPro20 low dose | Intervention Type: BIOLOGICAL; Name: Placebo; Assigned to Arm(s): Placebo | Intervention Type: BIOLOGICAL; Name: IgPro10; Assigned to Arm(s): IgPro20 high dose, IgPro20 low dose, Placebo | Intervention Type: BIOLOGICAL; Name: IgPro20 (high dose); Assigned to Arm(s): IgPro20 high dose
C: Arm Label: IgPro10; Type: EXPERIMENTAL; Interventions: Biological: 10% liquid formulation of human immunoglobulin | Intervention Type: BIOLOGICAL; Name: 10% liquid formulation of human immunoglobulin; Assigned to Arm(s): IgPro10
D: Arm Label: NPB-01; Type: EXPERIMENTAL; Interventions: Drug: NPB-01 | Intervention Type: DRUG; Name: NPB-01; Assigned to Arm(s): NPB-01

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Musculoskeletal Consequences of Pediatric Overweight - Efficiency of Different Interventions on Health, Motor and Psychosocial Development in Overweight and Obese Children
Brief Summary: The purpose was to investigate the consequences of pediatric overweight on the musculoskeletal system, postural control and proprioception, and to analyze prospectively the influence of ball games and nutrition counseling.


Options:
A: Arm Label: Treatment Group; Type: EXPERIMENTAL; Interventions: Behavioral: Physical Activity | Arm Label: Wait List Group; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Physical Activity | Intervention Type: BEHAVIORAL; Name: Physical Activity; Assigned to Arm(s): Treatment Group | Intervention Type: BEHAVIORAL; Name: Physical Activity; Assigned to Arm(s): Wait List Group
B: Arm Label: Non-overweight children in ball games program; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Ball games program | Arm Label: Overweight children in nutrition counseling program; Type: EXPERIMENTAL; Interventions: Behavioral: Nutrition counseling | Arm Label: Control group overweight children; Type: PLACEBO_COMPARATOR; Interventions: N/A | Arm Label: Overweight children in ball games program; Type: EXPERIMENTAL; Interventions: Behavioral: Ball games program | Arm Label: Overweight children in ball games and nutrition counseling; Type: EXPERIMENTAL; Interventions: Behavioral: Ball games program, Behavioral: Nutrition counseling | Arm Label: Non-overweight control (no intervention); Type: PLACEBO_COMPARATOR; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Ball games program; Assigned to Arm(s): Non-overweight children in ball games program, Overweight children in ball games and nutrition counseling, Overweight children in ball games program | Intervention Type: BEHAVIORAL; Name: Nutrition counseling; Assigned to Arm(s): Overweight children in ball games and nutrition counseling, Overweight children in nutrition counseling program
C: Arm Label: SCORES; Type: EXPERIMENTAL; Interventions: Behavioral: America SCORES, Bay Area | Arm Label: Usual care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: America SCORES, Bay Area; Assigned to Arm(s): SCORES
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: High or low Glycemic Index and high or low Protein Diet | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Behavioral: High or low Glycemic Index and high or low Protein Diet | Arm Label: 3; Type: EXPERIMENTAL; Interventions: Behavioral: High or low Glycemic Index and high or low Protein Diet | Arm Label: 4; Type: EXPERIMENTAL; Interventions: Behavioral: High or low Glycemic Index and high or low Protein Diet | Arm Label: 5; Type: EXPERIMENTAL; Interventions: Behavioral: High or low Glycemic Index and high or low Protein Diet | Intervention Type: BEHAVIORAL; Name: High or low Glycemic Index and high or low Protein Diet; Assigned to Arm(s): 1, 2, 3, 4, 5

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multicentre, Randomised, Open Label, Non-inferiority Trial to Evaluate the Efficacy and Safety of Deferiprone Compared to Deferasirox in Patients Aged From 1 Month to Less Than 18 Years Affected by Transfusion Dependent Haemoglobinopathies
Brief Summary: Multicentre, randomised, open label, non-inferiority active-controlled trial to evaluate efficacy and safety of a 12-months treatment with deferiprone (DFP) at dose of 75-100 mg/kg/day versus deferasirox (DFX) at dose of 20-40 mg/kg/day in paediatric patients (1 month \< 18 years old) affected by hereditary haemoglobinopathies and requiring frequent transfusions and chelation.


Options:
A: Arm Label: Deferiprone; Type: EXPERIMENTAL; Interventions: Drug: Deferiprone | Arm Label: Deferoxamine; Type: ACTIVE_COMPARATOR; Interventions: Drug: Deferoxamine | Intervention Type: DRUG; Name: Deferiprone; Assigned to Arm(s): Deferiprone | Intervention Type: DRUG; Name: Deferoxamine; Assigned to Arm(s): Deferoxamine
B: Arm Label: Deferasirox; Type: EXPERIMENTAL; Interventions: Drug: Deferasirox | Intervention Type: DRUG; Name: Deferasirox; Assigned to Arm(s): Deferasirox
C: Arm Label: Deferiprone + Desferrioxamine; Type: EXPERIMENTAL; Interventions: Drug: Deferiprone (L1), Drug: Desferrioxamine | Arm Label: Deferiprone single agent; Type: EXPERIMENTAL; Interventions: Drug: Deferiprone (L1) | Arm Label: Desferrioxamine single agent; Type: ACTIVE_COMPARATOR; Interventions: Drug: Desferrioxamine | Intervention Type: DRUG; Name: Deferiprone (L1); Assigned to Arm(s): Deferiprone + Desferrioxamine, Deferiprone single agent | Intervention Type: DRUG; Name: Desferrioxamine; Assigned to Arm(s): Deferiprone + Desferrioxamine, Desferrioxamine single agent
D: Arm Label: Deferiprone; Type: EXPERIMENTAL; Interventions: Drug: Deferiprone | Arm Label: Deferasirox; Type: ACTIVE_COMPARATOR; Interventions: Drug: Deferasirox | Intervention Type: DRUG; Name: Deferiprone; Assigned to Arm(s): Deferiprone | Intervention Type: DRUG; Name: Deferasirox; Assigned to Arm(s): Deferasirox

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effects of Simple Sodium Alignment on Short-, Medium- and Long-term Clinical and Laboratory Outcome Measures
Brief Summary: A difference between dialysate and serum sodium concentration leads to diffusive sodium transfer across the dialyzer membrane. The consequences of diffusive sodium flux into the patient can be chronic sodium overload leading to overhydration, hypertension, cardiovascular disease, and other problems. Diffusive sodium flux out of the patient can lead to intradialytic blood pressure instability. A simple strategy for alignment of dialysate and serum sodium concentrations was implemented starting in April/May 2010 in order to minimize the problems particularly associated with chronic sodium overload.


Options:
A: Arm Label: Standard; Type: NO_INTERVENTION; Interventions: Device: Standard Hemodialysis | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Device: with Blood Volume Management (BVM®) only | Arm Label: 3; Type: ACTIVE_COMPARATOR; Interventions: Device: with Blood Volume (BVM®) and Temperature (BTM®) on-line monitoring | Intervention Type: DEVICE; Name: Standard Hemodialysis; Assigned to Arm(s): Standard | Intervention Type: DEVICE; Name: with Blood Volume Management (BVM®) only; Assigned to Arm(s): 2 | Intervention Type: DEVICE; Name: with Blood Volume (BVM®) and Temperature (BTM®) on-line monitoring; Assigned to Arm(s): 3
B: Arm Label: Conventional hemodialysis; Type: ACTIVE_COMPARATOR; Interventions: Device: Conventional hemodialysis | Arm Label: Frequent hemodialysis; Type: EXPERIMENTAL; Interventions: Device: Frequent hemodialysis | Intervention Type: DEVICE; Name: Conventional hemodialysis; Assigned to Arm(s): Conventional hemodialysis | Intervention Type: DEVICE; Name: Frequent hemodialysis; Assigned to Arm(s): Frequent hemodialysis
C: Arm Label: Subjects undergoing sodium alignment; Type: N/A; Interventions: Other: Dialysate and serum sodium concentration aligned | Arm Label: Subjects not undergoing sodium alignment; Type: N/A; Interventions: N/A | Intervention Type: OTHER; Name: Dialysate and serum sodium concentration aligned; Assigned to Arm(s): Subjects undergoing sodium alignment
D: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Nocturnal home hemodialysis | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Behavioral: Nocturnal home hemodialysis | Intervention Type: BEHAVIORAL; Name: Nocturnal home hemodialysis; Assigned to Arm(s): 1, 2

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Life Enhancing Activities for Family Caregivers (LEAF)
Brief Summary: Life Enhancing Activities for Family Caregivers is a six-week program designed to increase positive affect in people who care for a family member with dementia. The intervention consists of 6 weekly one-hour sessions conducted one-on-one with a trained facilitator to teach simple skills that are practiced at home in a study-supplied workbook. The program is preceded and followed by a 30-45 minute questionnaire. Follow-up assessments will be conducted at 1-month, 3-months, and 6-months post intervention.

Primary hypothesis is that experimental subjects who participate in LEAF will demonstrate significantly greater improvements in psychological outcomes and will engage in more problem focused and positive appraisal forms of coping compared to the wait-list control condition.


Options:
A: Arm Label: Navigated Care; Type: EXPERIMENTAL; Interventions: Behavioral: Navigated Care | Arm Label: Survey of Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Navigated Care; Assigned to Arm(s): Navigated Care
B: Arm Label: positive affect intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Positive Affect | Arm Label: wait list control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Positive Affect; Assigned to Arm(s): positive affect intervention
C: Arm Label: Behavioral Activation; Type: EXPERIMENTAL; Interventions: Behavioral: Behavioral activation, Other: Psychoeducation | Arm Label: Psychoeducation; Type: ACTIVE_COMPARATOR; Interventions: Other: Psychoeducation | Intervention Type: BEHAVIORAL; Name: Behavioral activation; Assigned to Arm(s): Behavioral Activation | Intervention Type: OTHER; Name: Psychoeducation; Assigned to Arm(s): Behavioral Activation, Psychoeducation
D: Arm Label: Active treatment; Type: EXPERIMENTAL; Interventions: Behavioral: Video-based coping skills training with telephone coaching | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Video-based coping skills training with telephone coaching; Assigned to Arm(s): Active treatment

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Obstructive Sleep Apneas in Elderly:Neuroimaging Changes and Neurocognitive Function Before and After Treatment
Brief Summary: In the near future more than 20% of the European population will be over 65 years old and the prevalence of obstructive sleep apnea (OSA) in this aged population is known to be higher than 50%. OSA is a risk factor for cognitive dysfunction in middle-aged subjects, but the relationship between cognitive impairment and sleep breathing disorders (SBD) in the elderly has scarcely been observed.

The aim of this study is to investigate cognitive performance in elderly OSA patients, the corresponding brain morphology changes and biological markers and their reversibility with continuous positive airway pressure (CPAP) treatment.


Options:
A: Arm Label: Traditional; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Telemedicine Education Pathway; Type: EXPERIMENTAL; Interventions: Behavioral: Telemedicine Education | Arm Label: Telemedicine IVR Pathway; Type: EXPERIMENTAL; Interventions: Behavioral: IVR | Arm Label: Telemedicine Both Pathway; Type: EXPERIMENTAL; Interventions: Behavioral: Telemedicine Education, Behavioral: IVR | Intervention Type: BEHAVIORAL; Name: Telemedicine Education; Assigned to Arm(s): Telemedicine Both Pathway, Telemedicine Education Pathway | Intervention Type: BEHAVIORAL; Name: IVR; Assigned to Arm(s): Telemedicine Both Pathway, Telemedicine IVR Pathway
B: Arm Label: Sleep Unit group; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Primary Care group; Type: EXPERIMENTAL; Interventions: Other: Clinical follow up by general practitioners in primary care | Intervention Type: OTHER; Name: Clinical follow up by general practitioners in primary care; Assigned to Arm(s): Primary Care group
C: Arm Label: CPAP; Type: EXPERIMENTAL; Interventions: Device: CPAP, Other: Standard care for OSA | Arm Label: Standard care for OSA; Type: ACTIVE_COMPARATOR; Interventions: Other: Standard care for OSA | Intervention Type: DEVICE; Name: CPAP; Assigned to Arm(s): CPAP | Intervention Type: OTHER; Name: Standard care for OSA; Assigned to Arm(s): CPAP, Standard care for OSA
D: Arm Label: Primary.; Type: EXPERIMENTAL; Interventions: Device: Diagnosis, autoCPAP, follow up. | Arm Label: Hospital; Type: ACTIVE_COMPARATOR; Interventions: Device: Diagnosis, autoCPAP, follow up. | Intervention Type: DEVICE; Name: Diagnosis, autoCPAP, follow up.; Assigned to Arm(s): Hospital, Primary.

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Do Insulin Secretion or Genotype Pattern Predict Low Fat vs Low Carb Weight Loss Success?
Brief Summary: Genomics research is advancing rapidly, and links between genes and obesity continue to be discovered and better defined. A growing number of single nucleotide polymorphisms (SNPs) in multiple genes have been shown to alter an individual's response to dietary macronutrient composition. Based on prior genetic studies evaluating the body's physiological responses to dietary carbohydrates or fats, the investigators identified multi-locus genotype patterns with SNPs from three genes (FABP2, PPARG, and ADRB2): a low carbohydrate-responsive genotype (LCG) and a low fat-responsive genotype (LFG). In a preliminary, retrospective study (using the A TO Z weight loss study data), the investigators observed a 3-fold difference in 12-month weight loss for initially overweight women who were determined to have been appropriately matched vs. mismatched to a low carbohydrate (Low Carb) or low fat (Low Fat) diet based on their multi-locus genotype pattern. The primary objective of this study is to confirm and expand on the preliminary results and determine if weight loss success can be increased if the dietary approach (Low Carb vs. Low Fat) is appropriately matched to an individual' s genetic predisposition (Low Carb Genotype vs. Low Fat Genotype) toward those diets.


Options:
A: Arm Label: Experimental: Low-Carbohydrate Diet; Type: EXPERIMENTAL; Interventions: Behavioral: Low-Carbohydrate Diet, Behavioral: Mobile App | Arm Label: Experimental: Low-Fat Diet; Type: EXPERIMENTAL; Interventions: Behavioral: Low-Fat Diet, Behavioral: Mobile App | Intervention Type: BEHAVIORAL; Name: Low-Carbohydrate Diet; Assigned to Arm(s): Experimental: Low-Carbohydrate Diet | Intervention Type: BEHAVIORAL; Name: Low-Fat Diet; Assigned to Arm(s): Experimental: Low-Fat Diet | Intervention Type: BEHAVIORAL; Name: Mobile App; Assigned to Arm(s): Experimental: Low-Carbohydrate Diet, Experimental: Low-Fat Diet
B: Arm Label: Treatment One; Type: EXPERIMENTAL; Interventions: Behavioral: SMART 2.0 | Arm Label: Treatment Two; Type: EXPERIMENTAL; Interventions: Behavioral: SMART 2.0 | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: SMART 2.0; Assigned to Arm(s): Treatment One, Treatment Two
C: Arm Label: Standard; Type: EXPERIMENTAL; Interventions: Behavioral: Standard | Arm Label: Technology Supported condition; Type: EXPERIMENTAL; Interventions: Behavioral: Technology Supported | Arm Label: Self-Guided; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Technology Supported; Assigned to Arm(s): Technology Supported condition | Intervention Type: BEHAVIORAL; Name: Standard; Assigned to Arm(s): Standard
D: Arm Label: RIDE; Type: EXPERIMENTAL; Interventions: Behavioral: RIDE e-health application | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: RIDE e-health application; Assigned to Arm(s): RIDE

Answer: A