Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Effect of Daily Whole-Body Vibration on Tibial Trabecular Bone Mineral Density in Osteopenic Postmenopausal Women
Brief Summary: This study will examine whether whole-body vibration slows down bone loss in healthy postmenopausal women with osteopenia. Whole-body vibration is a promising novel therapy that involves standing on a platform which produces extremely small and fast up-and-down movements. Some but not all research studies have found that whole-body vibration slowed down bone loss in postmenopausal women. One of the reasons why different studies found different results may be because they used various speeds of vibration. This study looks at how different speeds of whole-body vibration influence bone mineral density differently in postmenopausal women who have osteopenia. Two hundred postmenopausal women will take part in this 12-month study. Women will be randomly assigned into three groups (67 women per group) and these groups will be compared. Group 1 will receive very fast whole-body vibration, Group 2 will receive fast whole-body vibration, and Group 3 will not receive whole-body vibration. We will look at various bone mineral density and bone quality measurements, obtained with three different types of technologies, at the beginning of the study and at 12 months of follow-up. The hypothesis of this study is that the in comparison to Group 3 (no vibration), Groups 1 and 2 will experience reduced bone loss over 12 months, and that the greatest reduction in bone loss will be experienced by Group 1. The results of this study will help us determine whether whole-body vibration at different speeds produces variable effects on bone, hence explaining the inconsistency of the results obtained in previous studies.


Options:
A: Arm Label: Lite OJ with Ca and VitD; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Reduced energy (lite) OJ fortified with Calcium and Vitamin D, Behavioral: Nutrition Counseling | Arm Label: Lite OJ without Ca and VitD; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Nutrition Counseling, Dietary Supplement: Reduced energy (lite) OJ without Calcium and Vitamin D | Intervention Type: DIETARY_SUPPLEMENT; Name: Reduced energy (lite) OJ fortified with Calcium and Vitamin D; Assigned to Arm(s): Lite OJ with Ca and VitD | Intervention Type: BEHAVIORAL; Name: Nutrition Counseling; Assigned to Arm(s): Lite OJ with Ca and VitD, Lite OJ without Ca and VitD | Intervention Type: DIETARY_SUPPLEMENT; Name: Reduced energy (lite) OJ without Calcium and Vitamin D; Assigned to Arm(s): Lite OJ without Ca and VitD
B: Arm Label: Calcitriol; Type: EXPERIMENTAL; Interventions: Drug: Calcitriol | Arm Label: placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Calcitriol | Intervention Type: DRUG; Name: Calcitriol; Assigned to Arm(s): Calcitriol, placebo
C: Arm Label: 90 Hz whole-body vibration; Type: EXPERIMENTAL; Interventions: Device: Juvent 1000 Dynamic Motion Therapy (DMT) Platform | Arm Label: 30 Hz whole-body vibration; Type: EXPERIMENTAL; Interventions: Device: Juvent 1000 Dynamic Motion Therapy (DMT) Platform | Arm Label: control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: Juvent 1000 Dynamic Motion Therapy (DMT) Platform; Assigned to Arm(s): 90 Hz whole-body vibration | Intervention Type: DEVICE; Name: Juvent 1000 Dynamic Motion Therapy (DMT) Platform; Assigned to Arm(s): 30 Hz whole-body vibration
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Dietary Supplement: calcium supplementation | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Dietary Supplement: calcium and vitamin D3 supplementation | Arm Label: 3; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Placebo | Intervention Type: DIETARY_SUPPLEMENT; Name: calcium supplementation; Assigned to Arm(s): 1 | Intervention Type: DIETARY_SUPPLEMENT; Name: calcium and vitamin D3 supplementation; Assigned to Arm(s): 2 | Intervention Type: DIETARY_SUPPLEMENT; Name: Placebo; Assigned to Arm(s): 3

Answer: C