TrialPanorama/Dataset huggingface dataset:
Please select the outcome measures that correspond to the clinical trial below.
Title: Investigating the Effects of Probiotic Yogurt on Reducing the Levels of Environmental Toxins Among School Children in Mwanza, Tanzania
Brief Summary: The primary objective of this pilot study is to determine if consumption of a probiotic yogurt causes reduced levels of environmental toxins in a group of school-aged Tanzanian children. The secondary objective is to determine the levels of environmental toxins in Tanzanian children and compare these to literature values of levels believed to negatively affect health and development. The third objective is to analyze the intestinal microbiota of the children and to determine if consumption of a probiotic yogurt has a significant affect on the microbiota composition.


Options:
A: Prevalence of atopic disease in infant (two years)
B: Gestational weight gain (week 36-37 of pregnancy); Change in glucose levels (Oral glucose tolerance test) (baseline (week 14-20) and 27-30 of pregnancy)
C: Spontaneous premature birth (<37, <35, <32 weeks of pregnancy) (24 weeks)
D: Changes in Body Toxin Levels (Before and after the 25 day intervention period.)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: LINK4HEALTH: A Combination Approach to Linkage and Retention for HIV (Human Immunodeficiency Virus) Infected Individuals in Swaziland
Brief Summary: Despite increased HIV (Human Immunodeficiency Virus) infection testing in Africa, many patients never enroll in subsequent HIV care after testing or remain in care after an initial enrollment. This study's aim is to improve linkage to HIV care and retention in HIV care through the use of feasible, evidence-based, and practical interventions. The study takes place in Swaziland, the country with the highest HIV prevalence (24%) in sub-Saharan Africa. The study will randomize groups of HIV testing sites and affiliated clinics to either standard of care or a combined intervention strategy (CIS) which consists of point-of care CD4 (cluster differentiation 4 (CD4)) testing at time of HIV testing, fast-track HIV medications for those who are eligible for treatment,mobile phone appointment reminders, care bags filled with health prevention materials, and financial incentives. The study outcomes are linkage to and retention in care as well as cost effectiveness, feasibility of interventions, and patient acceptability of interventions.


Options:
A: Survival, recurrence of presenting OI/bacterial infection (BI) or incidence of new AIDS-defining events, and HIV-1 plasma viral load at Week 48
B: Change in proportion of participants who both link to care at assigned study unit within 1 month and are retained in care at the designated study unit 12 months after HIV (Human Immunodeficiency Virus) diagnosis (one month after enrollment, 12 months after enrollment)
C: Change in the CSF CFUs between the immediate and standard ART initiation groups (4 weeks)
D: Receipt of post-test results and counseling following testing completeness (30 days)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Preventing Childhood Obesity Through Early Feeding and Parenting Guidance
Brief Summary: The goal of this study is to compare the effectiveness of structured CHW- provided home visits, using an intervention created through community-based participatory research, to standard care received through WIC office visits in preventing the development of overweight (weight/length \>85th percentile) and obesity (weight/length \>95th percentile) in infants during their first 2 years of life.

Hypothesis 1: Children in the intervention group will remain within their growth centiles in height/weight and weight for age, while children in the control group will increase in height/weight percentiles and weight percentiles more rapidly (\> .67 SD) during the first year of life.

Hypothesis 2: Fewer children who receive the intervention will have BMI \>95th percentile at ages 2 and 3 than the children in the control group.

Hypothesis 3: Children who receive the intervention will exclusively breastfeed for a longer period of time than will children in the control group.

Hypothesis 4: Children who receive the intervention will have a higher percentage of fruits and vegetables and a lower percentage of sweetened beverages, desserts, and candy in their diets at ages 1, 2, and 3, than will children in the control group.

Hypothesis 5: Parents in the intervention group will be more responsive to infant feeding cues (hunger, satiety)than parents in the control group.


Options:
A: Weight for Length Body Mass Index (BMI will be assessed at three years of age for the study participants)
B: BMI change from baseline to 12 months post-intervention (24 months postpartum) will be assessed via self-report and validated by in-person weight measurement. The proportion of women who lose 10% of baseline BMI
C: Exclusive Breastfeeding Rate (3 months postpartum)
D: Postpartum weight loss (12 months after delivery)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Preventing Childhood Obesity Through Early Feeding and Parenting Guidance
Brief Summary: The goal of this study is to compare the effectiveness of structured CHW- provided home visits, using an intervention created through community-based participatory research, to standard care received through WIC office visits in preventing the development of overweight (weight/length \>85th percentile) and obesity (weight/length \>95th percentile) in infants during their first 2 years of life.

Hypothesis 1: Children in the intervention group will remain within their growth centiles in height/weight and weight for age, while children in the control group will increase in height/weight percentiles and weight percentiles more rapidly (\> .67 SD) during the first year of life.

Hypothesis 2: Fewer children who receive the intervention will have BMI \>95th percentile at ages 2 and 3 than the children in the control group.

Hypothesis 3: Children who receive the intervention will exclusively breastfeed for a longer period of time than will children in the control group.

Hypothesis 4: Children who receive the intervention will have a higher percentage of fruits and vegetables and a lower percentage of sweetened beverages, desserts, and candy in their diets at ages 1, 2, and 3, than will children in the control group.

Hypothesis 5: Parents in the intervention group will be more responsive to infant feeding cues (hunger, satiety)than parents in the control group.


Options:
A: Preventing childhood obesity (Offspring age until six years)
B: Develop/evaluate effectiveness of a community-based intervention targets children of the Pacific Region who are overweight in order to slow and prevent further weight gain (for children to "grow into their weight") (Feb 2008 - Feb 2012)
C: Weight for Length Body Mass Index (BMI will be assessed at three years of age for the study participants)
D: N/A

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: ImPRoving Adherence to Immunosuppressive Therapy by Mobile Internet Application in Solid Organ Transplant Patients
Brief Summary: Nonadherence to immunosuppression is a leading cause of late graft rejection, chronic rejection and graft failure and it is regarded as a preventable cause of graft loss after solid organ transplantation. The purpose of this study is to evaluate whether mobile application for drug medication can enhance the drug adherence rate.


Options:
A: adherence rate (up to 6 months)
B: change from baseline BMI at 8 months (8th month)
C: 12-week immunosuppression medication adherence (12 weeks)
D: Medication Adherence Change from Baseline to 6 Months (6 months); Medication Adherence Change from 6 Months to 12 Months (12 months); Medication Adherence Change from Baseline to 12 Months (12)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: The Singapore Tele-technology Aided Rehabilitation in Stroke (STARS) Study: A Randomized Controlled Trial
Brief Summary: The primary hypothesis tested in this randomized control trial is that a tele-rehabilitation intervention involving video-conferencing with a therapist and use of wearable monitoring devices in the first three months after stroke results greater functional recovery using the Jette Late Life Functional and Disability Instrument (LLFDI) (primary outcome) among stroke at three months survivors compared to usual care.

The secondary hypotheses tested in this randomized control trial are that a tele-rehabilitation intervention involving video-conferencing with a therapist and use of wearable monitoring devices in the first three months after stroke results in:

* Functional recovery using the LLFDI at 6 months,
* Functional recovery using gait speed, 2-minute walk test and Shah modified Barthel Index at 3 and 6 months,
* Greater contact time with a therapist at 3 \& 6 months,
* Better balance at 3 \& 6 months,
* Better self-report health-related quality of life at 3 \& 6 months,
* Decreased health service utilization at 3 \& 6 months,
* Reduced caregiver burden at three months survivors compared to usual care at 3 \& 6 months.


Options:
A: Jette Late Life Functional and Disability Instrument (LLFDI) (3 months)
B: Naming ability assessed by NGA (four month post randomization)
C: Change From Baseline (7-days Post Discharge) to 90-days in the PROMIS-10 Global Quality of Life, Physical Health T-scores (Patient) (7 days and 90 days post discharge); Change From Baseline (7-days Post Discharge) to 90-days in the PROMIS-10 Global Quality of Life, Mental Health T-scores (Patient) (7 days and 90 days post discharge); Change From Baseline (7-days Post Discharge) to 90-days in the Bakas Caregiving Outcomes Scale Scores (Caregiver) (7 days and 90 days post discharge)
D: The distance on the 6 minute walking test (6MWT) (6 minutes)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: The Singapore Tele-technology Aided Rehabilitation in Stroke (STARS) Study: A Randomized Controlled Trial
Brief Summary: The primary hypothesis tested in this randomized control trial is that a tele-rehabilitation intervention involving video-conferencing with a therapist and use of wearable monitoring devices in the first three months after stroke results greater functional recovery using the Jette Late Life Functional and Disability Instrument (LLFDI) (primary outcome) among stroke at three months survivors compared to usual care.

The secondary hypotheses tested in this randomized control trial are that a tele-rehabilitation intervention involving video-conferencing with a therapist and use of wearable monitoring devices in the first three months after stroke results in:

* Functional recovery using the LLFDI at 6 months,
* Functional recovery using gait speed, 2-minute walk test and Shah modified Barthel Index at 3 and 6 months,
* Greater contact time with a therapist at 3 \& 6 months,
* Better balance at 3 \& 6 months,
* Better self-report health-related quality of life at 3 \& 6 months,
* Decreased health service utilization at 3 \& 6 months,
* Reduced caregiver burden at three months survivors compared to usual care at 3 \& 6 months.


Options:
A: Changes in MVPA (Moderate-to-Vigorous Physical Activity) bouts of participants from baseline to months 6 and 12 (Baseline, 6 and 12 months)
B: Rate of recruitment to the studies (12 weeks (pilot study))
C: Mean Daily Step Count (Change from baseline mean daily step count at 3 weeks (end of unblinded digital activity tracker intervention)); Mean Daily Step Count (Change from 3 weeks mean daily step count at 5 weeks (end of smart text messaging intervention))
D: Jette Late Life Functional and Disability Instrument (LLFDI) (3 months)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: The Singapore Tele-technology Aided Rehabilitation in Stroke (STARS) Study: A Randomized Controlled Trial
Brief Summary: The primary hypothesis tested in this randomized control trial is that a tele-rehabilitation intervention involving video-conferencing with a therapist and use of wearable monitoring devices in the first three months after stroke results greater functional recovery using the Jette Late Life Functional and Disability Instrument (LLFDI) (primary outcome) among stroke at three months survivors compared to usual care.

The secondary hypotheses tested in this randomized control trial are that a tele-rehabilitation intervention involving video-conferencing with a therapist and use of wearable monitoring devices in the first three months after stroke results in:

* Functional recovery using the LLFDI at 6 months,
* Functional recovery using gait speed, 2-minute walk test and Shah modified Barthel Index at 3 and 6 months,
* Greater contact time with a therapist at 3 \& 6 months,
* Better balance at 3 \& 6 months,
* Better self-report health-related quality of life at 3 \& 6 months,
* Decreased health service utilization at 3 \& 6 months,
* Reduced caregiver burden at three months survivors compared to usual care at 3 \& 6 months.


Options:
A: Motor Activity Log - Quality Of Movement (MAL-QOM) and Wolf Motor Function Test - Performance Time (WMFT-PT) (4 weeks (post-treatment) relative to baseline performance)
B: Fugl Meyer (FM) Assessment (Baseline, post intervention and 3 month follow-up)
C: Jette Late Life Functional and Disability Instrument (LLFDI) (3 months)
D: The primary outcome, caregiver's perceived social support, will be assessed by Medical Outcomes Study Social Support Scale. (Baseline, 3, 6 and 12-months post-stroke)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Phase 2b Randomized, Double-Blind, Placebo-Controlled Study to Assess the Pharmacodynamic Response, Safety, and Tolerability to 20 Weeks of Oral Dosing of AKB-6548 in Participants With Anemia Secondary to Chronic Kidney Disease (CKD), GFR Categories G3a-G5 (Stages 3, 4, AND 5) (Pre-Dialysis)
Brief Summary: The purpose of this study is to evaluate the hemoglobin response (efficacy), safety, and tolerability of orally administered AKB-6548 in participants with Chronic Kidney Disease (pre-dialysis) with anemia with dosing for 20 weeks.


Options:
A: Modeled Hgb Change From Baseline Over 4 Weeks of Treatment (Baseline (average of Week -2, -1 and Day 1) and Week 4)
B: Mean Change From Baseline in Hb Averaged Over Week 28 to Week 52 (Baseline (Day 1, Week 0) and Week 28 to Week 52.)
C: Percentage of Participants Achieving a Successful Hemoglobin Response (Weeks 19 and 20)
D: Mean Change in Hemoglobin From Baseline and Over the Evaluation Period (Mean Over Week 24 and 28) (Baseline (Day 1) and Week 24 to Week 28)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Effectiveness of Parenting Programs on Child Development and Maternal Well-being in Rural Uganda
Brief Summary: The purpose of the current study involves the development, implementation and evaluation of a parenting program to target maternal well-being and child health, growth and development in Lira, Uganda. The current study aims to address maternal care within a parenting program as well as parenting practices emphasizing nutrition, hygiene, and psychosocial stimulation through peer-support, practice and problem-solving. Outcomes include child health, growth and development, maternal mental health, mother-child interactions, and maternal-spousal relations.

We hypothesize that:

1. Children of parents who attend the parenting program will have better health, height and cognitive/language development at post-test, than children whose parents did not have the opportunity to attend parenting sessions.
2. Parents who attend the parenting program will have more knowledge about child development and provide more home stimulation, dietary diversity and preventive health practices than parents who do not have the opportunity to attend parenting sessions.
3. Mothers who attend the parenting program will have improved well-being compared to mothers who do not have the opportunity to attend parenting sessions.


Options:
A: Change from baseline in Bayley III Language scale (Baseline and 11 months)
B: Scale name unabbreviated: "La escala de Adopción del Rol Materno (ARM) de la Doctora María del Carmen Garrido Hidalgo y la Doctora Marleny Marchán Coronado". (4 Months); Perceived Maternal Parenting Self-Efficacy (PMP S-E) by Dr. Christopher R. Barnes and Dr. Elvidina N. Adamson-Macedo: measures maternal self-efficacy. (4 months); "Perinatal Infant Care Social Support Scale" (PICSS) by Dr. Patricia Leahy-Warren: Construct: measures social support and has been widely applied in first-time mothers. (4 months); "Bond between parents and children of MSc Alix Nathalya Vargas Vásquez and Doctor Myriam Patricia Pardo Torres" (4 months)
C: Retention in care in care 6 months post-transfer (6 months); Retention in care 12 months post-transfer (12 months); Retention in care 24 months post-transfer (24 months)
D: Mental health symptoms (6 weeks); Idiographic problems (6 weeks)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Care Transitions Innovation (C-TraIn): Study of a Multi-component Transitional Care Intervention for Uninsured and Low-income Publicly Insured Adults
Brief Summary: The purpose of this protocol is to evaluate the Care Transitons Innovation, a quality improvement project being implemented at OHSU to improve the transition from hospital to home for uninsured and Medicaid patients admitted to general medicine and cardiology wards at OHSU. The evaluation includes a baseline in-person survey and a 30 day post-discharge phone follow-up survey. Prior to C-TraIn, the local healthcare delivery model lacked an effective way to assure timely, safe, and effective follow-up care for uninsured and underinsured hospitalized patients. Most uninsured patients have no source for primary care, and many have limited social support, complex medical problems, and are prescribed many medications. Patients are frequently discharged without any coordinated plan for follow up. Based on a needs assessment performed in 2009 (OHSU eIRB 5514) investigators developed a quality improvement program that will include three major components: 1) a care transitions RN advocate who will see patients in the hospital and after discharge, 2) a pharmacy consultation and 30 days of medications post-discharge, 3) linkages with primary care medical homes, including payment for primary care for uninsured patients who lack a usual source of care, and 4) monthly meetings that serve as a platform for continuous quality improvement. In order to measure the success of our program, investigators will track patient utilization, sociodemographic factors, and patient factors including satisfaction, activation, and self-reported health status. To be included patients must be uninsured, have Oregon Medicaid, or be low income (200% or less of federal poverty level) Medicare recipients, and live within Multnomah, Washington and Clackamas Counties in Oregon.


Options:
A: Hospital readmission rate (all cause) (90 days)
B: Effects on hospital visits (1 year)
C: 30-day hospital readmissions (30-days); Emergency Department use (30-days post-discharge)
D: ADEs (Measured 30 and 90 days after hospital discharge); Medication appropriateness (Measured 30 and 90 days after hospital discharge by the Hanlon et al. Medication Appropriateness Index); Complications related to medications, including the number of hospital readmissions, unscheduled visits to emergency departments or urgent care facilities, and physician visits related to a medication problem or ADE (Measured 30 and 90 days after hospital discharge); Cost-effectiveness of the minimal or enhanced treatment compared to usual care (Measured 30 and 90 days after hospital discharge)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Care Transitions Innovation (C-TraIn): Study of a Multi-component Transitional Care Intervention for Uninsured and Low-income Publicly Insured Adults
Brief Summary: The purpose of this protocol is to evaluate the Care Transitons Innovation, a quality improvement project being implemented at OHSU to improve the transition from hospital to home for uninsured and Medicaid patients admitted to general medicine and cardiology wards at OHSU. The evaluation includes a baseline in-person survey and a 30 day post-discharge phone follow-up survey. Prior to C-TraIn, the local healthcare delivery model lacked an effective way to assure timely, safe, and effective follow-up care for uninsured and underinsured hospitalized patients. Most uninsured patients have no source for primary care, and many have limited social support, complex medical problems, and are prescribed many medications. Patients are frequently discharged without any coordinated plan for follow up. Based on a needs assessment performed in 2009 (OHSU eIRB 5514) investigators developed a quality improvement program that will include three major components: 1) a care transitions RN advocate who will see patients in the hospital and after discharge, 2) a pharmacy consultation and 30 days of medications post-discharge, 3) linkages with primary care medical homes, including payment for primary care for uninsured patients who lack a usual source of care, and 4) monthly meetings that serve as a platform for continuous quality improvement. In order to measure the success of our program, investigators will track patient utilization, sociodemographic factors, and patient factors including satisfaction, activation, and self-reported health status. To be included patients must be uninsured, have Oregon Medicaid, or be low income (200% or less of federal poverty level) Medicare recipients, and live within Multnomah, Washington and Clackamas Counties in Oregon.


Options:
A: Total Number of Rehospitalizations (Emergency Department Visits Plus Hospital Admissions) in the 30 Days After Discharge. (30 days after discharge)
B: Hospital readmission rate (all cause) (90 days)
C: 30-day hospital readmissions (30-days); Emergency Department use (30-days post-discharge)
D: Number of patients hospitalized due to COPD worsening (180 days)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Increase Protein Intake in Elderly
Brief Summary: The objective of this study is to investigate the acceptance, intake, and compliance of protein enriched bread and protein enriched yoghurt drinks in elderly patients in two real life settings (short term; hospital, and longer term; rehabilitation home).


Options:
A: The primary outcome measure is Quality of Life (6 months)
B: Evaluation of the effectiveness of the intervention -The main evaluation criteria which will allow the effectiveness of this intervention to be evaluated are the reduction in the loss of autonomy measured by the DA/IDA scale. (Baseline, 6 months, 12 months)
C: Nutritional status; Quality of life; Physical performance
D: Protein intake measured on an individual level over 24h (3 days (hospital), 3 weeks (rehabilitation home))

Answer: D