TrialPanorama/Dataset huggingface dataset:
Please select the outcome measures that correspond to the clinical trial below.
Title: Plasma Exchange and Glucocorticoid Dosing in the Treatment of Anti-neutrophil Cytoplasm Antibody Associated Vasculitis: an International Randomized Controlled Trial
Brief Summary: The purpose of this study is to determine whether plasma exchange as well as immunosuppressive therapy are effective in reducing death and end-stage renal disease (ESRD). The trial will also study whether a reduced cumulative dosing regimen of glucocorticoids is as effective as a standard disease regimen.

The FDA-OOPD is one of the funding sources for this study.


Options:
A: Time to First Relapse (Approximately up to 4 years)
B: Number of side effects (morbidity) (at 3 years)
C: Composite of i) All-cause Mortality or ii) End-stage Renal Disease (Time frame varied by subject: minimum of 1 year - maximum of 7 years)
D: Relapse-free Survival (Any patients who have not relapsed at up to a maximum of 4 years will be censored.)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: A Randomised, Placebo-controlled Trial of Erythropoietin in ICU Patients With Traumatic Brain Injury
Brief Summary: This study seeks to determine if erythropoietin alpha (EPO) administered to adult critical care patients with moderate or severe traumatic brain injury improves neurological function assessed at six months after injury.


Options:
A: The primary objective of this study is to demonstrate that the administration of epoetin alfa to critically ill subjects reduces the proportion of subjects requiring red blood cell (RBC) transfusion as compared with placebo at Study Day 29.
B: mean change (%) from baseline in urinary NGAL concentration at 96 hr after rhu EPO injection (4 days)
C: incidence of acute kidney injury (change of renal function including SCr, cystatin C, creatinine clearance from 24 h before operation to postoperative day (POD) 5)
D: Combined proportion of unfavourable neurological outcomes at 6 months: severe disability (defined as GOSE scores 2-4) or death (GOSE score 1). (6 months)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: N/A
Brief Summary: The aim of this study is to test whether a parent-focused participatory intervention in addition to gym lessons can enhance preschoolers physical activity compared to gym lessons alone.


Options:
A: Change from baseline in physical activity level at 12-weeks (Baseline, 6-weeks and 12-weeks after study initiation)
B: Change in Educators' Observed Implementation Fidelity Scores for Use of Evidence-Based Obesity Practices (From Baseline Up to 8 months)
C: Absolute change in mean accelerometry counts over 6 days (baseline, end of intervention, six months after end of intervention)
D: Change in Body Mass Index (Baseline, 8 months, 21 months)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: N/A
Brief Summary: The aim of this study is to test whether a parent-focused participatory intervention in addition to gym lessons can enhance preschoolers physical activity compared to gym lessons alone.


Options:
A: Change in Educators' Observed Implementation Fidelity Scores for Use of Evidence-Based Obesity Practices (From Baseline Up to 8 months)
B: Caloric intake in the Eating in the Absence of Hunger (EAH) paradigm (week 4)
C: Absolute change in mean accelerometry counts over 6 days (baseline, end of intervention, six months after end of intervention)
D: Change in The Environment and Policy Assessment and Observation tool (EPAO) score (3 years)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: N/A
Brief Summary: The aim of this study is to test whether a parent-focused participatory intervention in addition to gym lessons can enhance preschoolers physical activity compared to gym lessons alone.


Options:
A: N/A
B: Change in child adiposity from baseline measured via BMI z-score (Enrollment, 6 months, 12 months, 18 months, 24 months); Change in adult adiposity from baseline measured via BMI (Enrollment, 12 months, 24 months)
C: Percent of children overweight or obese (BMI ≥ 85th%) at 2 years of life (2 years)
D: Absolute change in mean accelerometry counts over 6 days (baseline, end of intervention, six months after end of intervention)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: N/A
Brief Summary: The aim of this study is to test whether a parent-focused participatory intervention in addition to gym lessons can enhance preschoolers physical activity compared to gym lessons alone.


Options:
A: Absolute change in mean accelerometry counts over 6 days (baseline, end of intervention, six months after end of intervention)
B: BMI variation from baseline (12 months)
C: Intake of nutrients; Serum lipid and lipoprotein concentrations; Growth and development; Smoking; Physical activity level and fitness; Intima-media thickness of arteries and rate of NO-induced vasodilatation
D: BMI z score (24 months (end of intervention)); BMI z score (60 months of age (followup at 5 years of age)); BMI z score (Follow-up at 11 years of age)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: N/A
Brief Summary: The aim of this study is to test whether a parent-focused participatory intervention in addition to gym lessons can enhance preschoolers physical activity compared to gym lessons alone.


Options:
A: Body mass index (2005, 2006, 2007, 2008); nutrition behavior (2005, 2006, 2007, 2008); physical activity (2005, 2006, 2007, 2008)
B: Change in intake of the target vegetable (Change in intake of the target vegetable from Baseline to day 14)
C: Change in children's Knowledge, attitude, habit (KAH) scores (baseline and 5 months)
D: Absolute change in mean accelerometry counts over 6 days (baseline, end of intervention, six months after end of intervention)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: N/A
Brief Summary: The aim of this study is to test whether a parent-focused participatory intervention in addition to gym lessons can enhance preschoolers physical activity compared to gym lessons alone.


Options:
A: Exclusive Breastfeeding at Four Months of Age (Six months after the beginning of the study)
B: Change in physical activity (Participants' physical activity will be measure over the course of 5 consecutive school days pre-intervention and 5 consecutive school days post-intervention)
C: Body mass index (2005, 2006, 2007, 2008); nutrition behavior (2005, 2006, 2007, 2008); physical activity (2005, 2006, 2007, 2008)
D: Absolute change in mean accelerometry counts over 6 days (baseline, end of intervention, six months after end of intervention)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: N/A
Brief Summary: The aim of this study is to test whether a parent-focused participatory intervention in addition to gym lessons can enhance preschoolers physical activity compared to gym lessons alone.


Options:
A: Child percent body fat after the 8-month intervention period, controlling for baseline percent body fat. Percent body fat will be calculated using Dezenberg's equation which takes into account child height, weight, gender, race, and tricep skinfolds. (baseline, 8 months and 14 months)
B: Physical Activity Level (The intervention spans a period of 6 months. Outcomes are measured before and after intervention.); Physical Literacy (The intervention spans a period of 6 months. Outcomes are measured before and after intervention.); Dietary Intake (The intervention spans a period of 6 months. Outcomes are measured before and after intervention.)
C: fasting blood glucose (Baseline to 10 months postpartum); weight (body mass index) (Baseline to 10 months postpartum)
D: Absolute change in mean accelerometry counts over 6 days (baseline, end of intervention, six months after end of intervention)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: N/A
Brief Summary: The aim of this study is to test whether a parent-focused participatory intervention in addition to gym lessons can enhance preschoolers physical activity compared to gym lessons alone.


Options:
A: Absolute change in mean accelerometry counts over 6 days (baseline, end of intervention, six months after end of intervention)
B: Change in Body Mass Index Z-score (9 months)
C: Body mass index BMI: derived from measured body height (m) and body weight (kg) as body weight / height² (At age 11 years and 18 years)
D: Change in Prevalence of Overweight and Obesity Using Body Mass Index Percentile for Age and Sex (Baseline, 24 months); Change in Waist Circumference (Baseline, 78 months); Prevalence of Acanthosis Nigricans (Baseline, 24 months); Change in Prevalence of Overweight and Obesity Using Body Mass Index Percentile for Age and Sex (Baseline, 78 months); Change in Waist Circumference (Baseline, 24 months); Prevalence of Acanthosis Nigricans (Baseline, 78 months)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: N/A
Brief Summary: The aim of this study is to test whether a parent-focused participatory intervention in addition to gym lessons can enhance preschoolers physical activity compared to gym lessons alone.


Options:
A: Vitamin D plasma concentrations (12 months)
B: Increase physical activity (2010); Increase the intake of fiber (2010); Decrease fat intake (2010); Decrease television and other screen time (2010); Decrease obesity (2010)
C: Absolute change in mean accelerometry counts over 6 days (baseline, end of intervention, six months after end of intervention)
D: Fruit and Vegetable Consumption, servings per week (3 weeks); Perceived Behavioral Control scale score (3 weeks); Attitudes scale score (3 weeks); Intrinsic Motivation scale score (3 weeks); Fruit and vegetable consumption, servings per week (5 weeks); Perceived Behavioral Control scale score (5 weeks); Attitudes scale score (5 weeks); Intrinsic Motivation scale score (5 weeks)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: N/A
Brief Summary: The aim of this study is to test whether a parent-focused participatory intervention in addition to gym lessons can enhance preschoolers physical activity compared to gym lessons alone.


Options:
A: To evaluate and compare in overweight children the effectiveness of the following interventions: a parent-centered dietary modification program; a physical activity skill development program; and a parent-centered dietary modification + physical activity skill development program.
B: Absolute change in mean accelerometry counts over 6 days (baseline, end of intervention, six months after end of intervention)
C: Change in Weight Status (baseline and 2 year follow-up)
D: Change in Nutrition and Physical Activity Policies (Baseline, Year 1, Year 2)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: N/A
Brief Summary: The aim of this study is to test whether a parent-focused participatory intervention in addition to gym lessons can enhance preschoolers physical activity compared to gym lessons alone.


Options:
A: To evaluate and compare in overweight children the effectiveness of the following interventions: a parent-centered dietary modification program; a physical activity skill development program; and a parent-centered dietary modification + physical activity skill development program.
B: Child BMI Z-score (Pre-intervention); Child BMI Z-score (post-intervention); Child BMI Z-score (6-months post-intervention); Child BMI Z-score (12-months post-intervention)
C: Absolute change in mean accelerometry counts over 6 days (baseline, end of intervention, six months after end of intervention)
D: Child BMI Percentile (2 years after recruitment)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Linking Hospitalized Injection Drug Users to Buprenorphine
Brief Summary: This study tests whether starting Suboxone (buprenorphine) during a medical hospitalization, and then providing an appointment (a "link") for after discharge to maintenance buprenorphine in an outpatient setting will reduce HIV risk behavior in individuals who inject opioids.


Options:
A: opiate use
B: Opiate abstinence
C: opioid use (baseline, 1-month, 3-months, 6-months); HIV risk behavior (baseline, 1-month, 3-months, 6-months)
D: percentage of subjects abstinent from all opioids through the final day of detoxification (up to 12-week trial)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Linking Hospitalized Injection Drug Users to Buprenorphine
Brief Summary: This study tests whether starting Suboxone (buprenorphine) during a medical hospitalization, and then providing an appointment (a "link") for after discharge to maintenance buprenorphine in an outpatient setting will reduce HIV risk behavior in individuals who inject opioids.


Options:
A: opioid use (baseline, 1-month, 3-months, 6-months); HIV risk behavior (baseline, 1-month, 3-months, 6-months)
B: Opiate abstinence
C: OOWS Score (Change from baseline in OOWS score at 180 minutes (15 minutes post naloxone administration))
D: Percentage of patients in each group successfully inducted onto Vivitrol (Completion of 7-day detoxification)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: School Children and Adolescents as Health Experts - Step 3
Brief Summary: The purpose of the study is to determine whether a school based health promotion program in secondary schools is effective with respect to an increase of physical activity, physical fitness and health.


Options:
A: Change in body mass index (BMI). (Baseline through Follow-up: Grades 5-6-7-8)
B: Change in minutes spent in moderate to vigorous physical activity in after school programs from baseline to end of intervention (7 months) and 1 year after end of intervention. (Baseline, end of intervention (7 months), 1 year after intervention)
C: Daily physical activity > 60 minutes (4 years)
D: Executive function (One year)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: School Children and Adolescents as Health Experts - Step 3
Brief Summary: The purpose of the study is to determine whether a school based health promotion program in secondary schools is effective with respect to an increase of physical activity, physical fitness and health.


Options:
A: Body mass index (BMI) >= 85th percentile, adjusted for gender and age (baseline, end of 7th grade, end of study); Fasting glucose (mg/dL) (baseline, end of study); Fasting insulin (mU/mL) (baseline, end of study)
B: MET-weighted MVPA: Daily Minutes of Moderate-to-vigorous Physical Activity (MVPA) Weighted by Metabolic Equivalent of Task (MET) (Post-2 year intervention); MET-weighted MVPA: Daily Minutes of Moderate-to-vigorous Physical Activity (MVPA) Weighted by Metabolic Equivalent of Task (MET) (Post-3 year intervention)
C: HIV-1 seroincidence; HSV2 seroprevalence
D: Daily physical activity > 60 minutes (4 years)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: School Children and Adolescents as Health Experts - Step 3
Brief Summary: The purpose of the study is to determine whether a school based health promotion program in secondary schools is effective with respect to an increase of physical activity, physical fitness and health.


Options:
A: Body mass index (BMI) >= 85th percentile, adjusted for gender and age (baseline, end of 7th grade, end of study); Fasting glucose (mg/dL) (baseline, end of study); Fasting insulin (mU/mL) (baseline, end of study)
B: Percent Body Fat (Baseline and One year)
C: Daily physical activity > 60 minutes (4 years)
D: N/A

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: School Children and Adolescents as Health Experts - Step 3
Brief Summary: The purpose of the study is to determine whether a school based health promotion program in secondary schools is effective with respect to an increase of physical activity, physical fitness and health.


Options:
A: Overweight and obesity according to IOTF references (0-1-2 years)
B: Growth trajectories (using BMI, waist circumference), body composition (3 months)
C: NeuroCognitive Assessment (Change from baseline, 36 - 40 weeks); Structural Magnetic Resonance Imaging (Change from baseline, 36 - 40 weeks); Functional Magnetic Resonance Imaging (Change from baseline, 36 - 40 weeks); Academic Achievement (Change from baseline, 36 - 40 weeks); Eye Tracking (Change from baseline, 36 - 40 weeks); Task Performance (Change from baseline, 36 - 40 weeks)
D: Daily physical activity > 60 minutes (4 years)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Comparative Follow-up Schedule With Home Monitoring
Brief Summary: The study investigates whether home monitoring follow-up of Pace-Maker patients is as efficient as conventional method in terms of Significant Serious Adverse Event (SSAE).


Options:
A: Number of patients with serious adverse events detected during and at the end of an 18 months follow-up period is compared for the two groups (18 months)
B: Dyspnea; Exercise adherence and performance; Pulmonary exacerbations
C: Percentage of subjects with average day-time ambulatory blood pressure <135/85 mmHg (6 months); Percentage of subjects with average day-time ambulatory blood pressure <135/85 mmHg (12 months)
D: BP control at primary care visit; Systolic and diastolic BPs as recorded at each primary care provider visit during 24 month enrollment period.

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Effect of Aerobic Training on Psychosocial Morbidity, Symptoms, Airway Inflammation and Autonomic Modulation in Asthmatic Patients
Brief Summary: The investigators hypothesize that aerobic training can reduce anxiety, depression and airway inflammation and those benefits may be related to changes in autonomic system.


Options:
A: Bronchial hyperresponsiveness (Before and after 3 months of intervetion)
B: Clinical Control (Before and after 3 months of intervention)
C: Asthma control Questionnaire (Juniper) (Within 1 week of completion of the intervention (i.e., after 12 weeks))
D: psychosocial morbidity and airway inflammation (3 months)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Post-Operative Crohn's Disease Endoscopic Recurrence "POCER" Study: Endoscopic Guided Therapeutic Intervention & Determination of Cause
Brief Summary: This randomised, controlled study aims to evaluate the impact of endoscopic assessment, and adjustment of therapy, after surgery in patients with Crohn's disease. The primary endpoint is the severity of endoscopic recurrence. In addition, tissue will be collected for microbiological and immunological analysis.


Options:
A: remission without corticosteroids and without surgical resection (month 6 and 12 after inclusion)
B: Endoscopic recurrence of disease (18 months)
C: Percentage of Participants With Mucosal Healing and No Deep Ulcerations (48 weeks after Randomization)
D: Endoscopic remission (Week 102)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Post-Operative Crohn's Disease Endoscopic Recurrence "POCER" Study: Endoscopic Guided Therapeutic Intervention & Determination of Cause
Brief Summary: This randomised, controlled study aims to evaluate the impact of endoscopic assessment, and adjustment of therapy, after surgery in patients with Crohn's disease. The primary endpoint is the severity of endoscopic recurrence. In addition, tissue will be collected for microbiological and immunological analysis.


Options:
A: Clinical remission (CDAI<150). (56 weeks)
B: Percentage of Subjects Achieving Clinical Remission (Week 156)
C: Number of Participants Who Had Clinical Remission at Week 52 of Double-blind Treatment (Week 52 of double-blind treatment)
D: Endoscopic recurrence of disease (18 months)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Post-Operative Crohn's Disease Endoscopic Recurrence "POCER" Study: Endoscopic Guided Therapeutic Intervention & Determination of Cause
Brief Summary: This randomised, controlled study aims to evaluate the impact of endoscopic assessment, and adjustment of therapy, after surgery in patients with Crohn's disease. The primary endpoint is the severity of endoscopic recurrence. In addition, tissue will be collected for microbiological and immunological analysis.


Options:
A: Number of endoscopic recurrences (52 weeks after the begin of the study)
B: The primary endpoint was therapeutic failure at one year, defined as CDAI score ≥200 and an increase of ≥60 points from baseline, or study drug discontinuation due to lack of efficacy or intolerable adverse drug reaction. (12 months)
C: Endoscopic recurrence of disease (18 months)
D: Endoscopic remission (Week 102)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Preoperative Methylprednisolone in Endovascular Aortic Repair - a Randomized Double Blind Placebo Controlled Clinical Trial
Brief Summary: The purpose of this study is to attenuate the systemic inflammatory response after Endovascular repair of abdominal aortic aneurysms, by administration of a single preoperative dosage of Methylprednisolone.


Options:
A: Incidence of Low Cardiac Output Syndrome (LCOS) (first 48 hours after cardiac intensive care unit (CICU) admission post-op)
B: Difference in occurrence of postoperative cognitive dysfunction between control and intervention group at six days after surgery as determined by using a validated battery of cognitive tests (9 days)
C: Primary Endpoint: Number of Participants With Low Cardiac Output Syndrome (LCOS) or Death at 36 Hours From Admission to the Intensive Care Unit (ICU) After Surgery. (36 hours)
D: Systemic inflammatory response syndrome - SIRS (Within 5 postoperative days)

Answer: D