Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multi-center, Open-label, Prospective, Randomized, Parallel Group, Long-term Study Investigating a Standard Regimen in de Novo Kidney Transplant Patients Versus a CNI-free Regimen and a CNI-low Dose Regimen
Brief Summary: The purpose of this study is to compare renal function of immunosuppressive regimens with different relevance of the calcineurin inhibitor (CNI) cyclosporine: standard dose CNI, low dose CNI, CNI free in de novo kidney transplant patients after 12 months of therapy.


Options:
A: Arm Label: CNI standard regimen; Type: ACTIVE_COMPARATOR; Interventions: Drug: Myfortic, Drug: Sandimmun Optoral, Drug: Simulect® | Arm Label: CNI free regimen; Type: EXPERIMENTAL; Interventions: Drug: Everolimus, Drug: Myfortic, Drug: Sandimmun Optoral | Arm Label: CNI low regimen; Type: ACTIVE_COMPARATOR; Interventions: Drug: Everolimus, Drug: Sandimmun Optoral | Intervention Type: DRUG; Name: Everolimus; Assigned to Arm(s): CNI free regimen, CNI low regimen | Intervention Type: DRUG; Name: Myfortic; Assigned to Arm(s): CNI free regimen, CNI standard regimen | Intervention Type: DRUG; Name: Sandimmun Optoral; Assigned to Arm(s): CNI free regimen, CNI low regimen, CNI standard regimen | Intervention Type: DRUG; Name: Simulect®; Assigned to Arm(s): CNI standard regimen
B: Intervention Type: DRUG; Name: Everolimus; Assigned to Arm(s): N/A
C: Arm Label: Low-dose Everolimus Group; Type: EXPERIMENTAL; Interventions: Drug: Everolimus, Drug: Cyclosporine A (CsA), Drug: Basiliximab, Drug: Corticosteroids | Arm Label: High-dose Everolimus Group; Type: EXPERIMENTAL; Interventions: Drug: Everolimus, Drug: Cyclosporine A (CsA), Drug: Basiliximab, Drug: Corticosteroids | Arm Label: Control Group; Type: ACTIVE_COMPARATOR; Interventions: Drug: Mycophenolic Acid (MPA), Drug: Cyclosporine A (CsA), Drug: Basiliximab, Drug: Corticosteroids | Intervention Type: DRUG; Name: Everolimus; Assigned to Arm(s): High-dose Everolimus Group, Low-dose Everolimus Group | Intervention Type: DRUG; Name: Mycophenolic Acid (MPA); Assigned to Arm(s): Control Group | Intervention Type: DRUG; Name: Cyclosporine A (CsA); Assigned to Arm(s): Control Group, High-dose Everolimus Group, Low-dose Everolimus Group | Intervention Type: DRUG; Name: Basiliximab; Assigned to Arm(s): Control Group, High-dose Everolimus Group, Low-dose Everolimus Group | Intervention Type: DRUG; Name: Corticosteroids; Assigned to Arm(s): Control Group, High-dose Everolimus Group, Low-dose Everolimus Group
D: Arm Label: Calcineurin free; Type: EXPERIMENTAL; Interventions: Drug: Sirolimus, Drug: Prednisone, Drug: Mycophenolate mofetil, Procedure: Protocol biopsies | Arm Label: Calcineurin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Cyclosporine A, Drug: Prednisone, Drug: Mycophenolate mofetil, Procedure: Protocol biopsies | Intervention Type: DRUG; Name: Sirolimus; Assigned to Arm(s): Calcineurin free | Intervention Type: DRUG; Name: Cyclosporine A; Assigned to Arm(s): Calcineurin | Intervention Type: DRUG; Name: Prednisone; Assigned to Arm(s): Calcineurin, Calcineurin free | Intervention Type: DRUG; Name: Mycophenolate mofetil; Assigned to Arm(s): Calcineurin, Calcineurin free | Intervention Type: PROCEDURE; Name: Protocol biopsies; Assigned to Arm(s): Calcineurin, Calcineurin free

Answer: A