Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Phase 3 Study of Hypertonic Resuscitation Following Traumatic Injury With Hypovolemic Shock
Brief Summary: The purpose of this study is to determine if hypertonic saline with and without dextran can improve overall survival in victims of trauma with shock.

Injury and lost blood from trauma can cause your body to be in shock (low blood pressure related to blood loss). This decreased blood flow can lead to organ damage. In order to restore the blood pressure and blood flow, the medics give fluids into the patients' veins as soon as possible. This is called "resuscitation." The resuscitation fluid most commonly used is "isotonic" or one that is the same concentration as the blood. The investigators are trying to determine if infusing a "hypertonic" fluid (or one more concentrated than the blood) can increase the blood pressure and restore blood flow more efficiently. The hypertonic fluids the investigators are using are called hypertonic saline with dextran (HSD) and hypertonic saline (no dextran). Hypertonic saline is a salt solution that is slightly more concentrated than your blood. Dextran is a sugar solution.


Options:
A: Arm Label: 7.5% hypertonic saline/6% dextran (HSD); Type: EXPERIMENTAL; Interventions: Drug: 7.5% Hypertonic Saline in 6% Dextran-70 (HSD) | Arm Label: 7.5% hypertonic saline (HS); Type: EXPERIMENTAL; Interventions: Drug: 7.5% Hypertonic Saline (HS) | Arm Label: 0.9% normal saline (NS); Type: PLACEBO_COMPARATOR; Interventions: Drug: 0.9% Normal Saline (NS) | Intervention Type: DRUG; Name: 7.5% Hypertonic Saline in 6% Dextran-70 (HSD); Assigned to Arm(s): 7.5% hypertonic saline/6% dextran (HSD) | Intervention Type: DRUG; Name: 7.5% Hypertonic Saline (HS); Assigned to Arm(s): 7.5% hypertonic saline (HS) | Intervention Type: DRUG; Name: 0.9% Normal Saline (NS); Assigned to Arm(s): 0.9% normal saline (NS)
B: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: 7.5% hypertonic saline/6% Dextran-70 (HSD) | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Drug: 7.5% hypertonic saline (HS) | Arm Label: 3; Type: PLACEBO_COMPARATOR; Interventions: Drug: 0.9% normal saline | Intervention Type: DRUG; Name: 7.5% hypertonic saline/6% Dextran-70 (HSD); Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: 7.5% hypertonic saline (HS); Assigned to Arm(s): 2 | Intervention Type: DRUG; Name: 0.9% normal saline; Assigned to Arm(s): 3
C: Arm Label: HES 130/0.4; Type: EXPERIMENTAL; Interventions: Drug: 6% Hydroxyethyl starch 130/0.4 | Arm Label: Ringer acetate; Type: ACTIVE_COMPARATOR; Interventions: Drug: Ringers acetate | Intervention Type: DRUG; Name: 6% Hydroxyethyl starch 130/0.4; Assigned to Arm(s): HES 130/0.4 | Intervention Type: DRUG; Name: Ringers acetate; Assigned to Arm(s): Ringer acetate
D: Arm Label: 1, Albumin and Crystalloids; Type: OTHER; Interventions: Other: Albumin and Crystalloids | Arm Label: 2, Crystalloids; Type: OTHER; Interventions: Other: Crystalloids | Intervention Type: OTHER; Name: Albumin and Crystalloids; Assigned to Arm(s): 1, Albumin and Crystalloids | Intervention Type: OTHER; Name: Crystalloids; Assigned to Arm(s): 2, Crystalloids

Answer: B