Please select the eligibility criteria that correspond to the clinical trial below.
Title: Risk Reduction for Drug Use and Sexual Revictimization
Brief Summary: The investigator proposes to evaluate Risk Reduction through Family Therapy (RRFT), which integrates: 1) an ecologically-based intervention for treatment of substance abuse behaviors in high risk adolescents, 2) exposure-based cognitive-behavioral therapy for sexually assaulted youth, and 3) psychoeducation strategies for prevention of risky sexual behaviors and revictimization. The principal purpose of this research proposal is to evaluate the efficacy of RRFT in reducing the risk of drug abuse and other risky behaviors, PTSD, and revictimization among adolescents who have been sexually assaulted. The Research Plan will be conducted based on Stage 1a and Stage 1b from NIDA's Behavioral Therapies Development Program as described in Rounsaville, Carroll, \& Onken (2001). The final phase of the research will involve conducting a pilot randomized controlled trial of RRFT in a sample of adolescents, comparing primary outcome measures of youth receiving RRFT to youth receiving usual care in the community. Participants will be adolescents (12-17 years) who have experienced a sexual assault. Assessment of substance use and other risk behaviors, trauma-related psychopathology, and incidents of revictimization will be collected at pre- and post- treatment, as well as 6-week and 3-month follow-ups. Hierarchical Linear Modeling will be the primary method used to test study hypotheses. Development and evaluation of the proposed intervention will have significant implications for addressing public health problems in adolescent substance abuse and related high risk behaviors.


Options:
A: Inclusion Criteria:

1. Latino adults
2. 18 years of age or older
3. Current smoker with a history of smoking an average of at least 1 cigarette per day during the last year
4. Overweight/obese (BMI greater than or equal to 25)
5. Functioning telephone number
6. Valid home address
7. Ability to engage in low to moderate physical activity as determined by the Physical Activity Readiness Questionnaire (PAR-Q)
8. Blood Pressure readings \<140/90 mm Hg as defined by the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; Pressure readings \>/=140/90 mm Hg will be deemed ineligible to participate and excluded from the study. They will be referred to their family physician or community services. Those ineligible based on their initial blood pressure reading are allowed to participate if they provide a letter from a physician who will continue to monitor the participant during the research study.
9. Can speak, read, and understand Spanish and/or English

Exclusion Criteria:

1. Pregnancy or lactation
2. Participants who were recruited for the pilot and focus groups are not eligible for the randomized trial.
3. Contraindication for nicotine patch use
4. Regular use of tobacco products
5. Current use of tobacco cessation medications
6. Currently enrolled in another smoking cessation study
7. Another household member enrolled in the study
8. Scores below 38 on the Short Assessment of Health Literacy for Spanish Adults (SAHLSA)
9. Active substance abuse or dependence
10. Scores below the 6th grade literacy level on the Rapid Estimate of Adult Literacy in Medicine (REALM)
B: Inclusion Criteria:

* memorable sexual assault

Exclusion Criteria:

* active psychosis
* active suicidality
C: Inclusion Criteria:

* Women \<29 weeks gestation
* No previous live births
* At least 2 socio-demographic risk characteristics; e.g. unmarried, \<12 years of education, unemployed.
D: Inclusion Criteria:

* adolescents (ages 14-18) presenting to the ED for a medical injury or illness (except exclusions as noted below)
* adolescents ability to provide informed assent/consent depending on age
* access to a parent or guardian to provide informed consent

Exclusion Criteria:

* adolescents who do not understand English
* prisoners
* adolescents classified by medical staff as "Level 1" trauma
* adolescents deemed unable to provide informed consent
* adolescents treated in the ED for suicide attempts
* adolescents triaged to the psychiatric ED

Answer: B