Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Single-centre, Double-blind, Randomised, Two-stage, Parallel-group Study to Assess the Efficacy and Safety of the Fixed Dose Combination of Ibuprofen 400 mg and Caffeine 100 mg Versus Ibuprofen 400 mg, Caffeine 100 mg and Placebo in Patients With Postoperative Dental Pain
Brief Summary: The primary objective of this study is to compare the efficacy of a combination product containing ibuprofen 400 mg and caffeine 100 mg versus either ingredient alone as well as placebo for the treatment of post-surgical dental pain over an eight-hour period followed by a single dose of study medication (study stage 1). A secondary objective is to evaluate efficacy of multiple doses of the combination in comparison to ibuprofen alone over a 5-day post-surgical period (study stage 2).


Options:
A: Arm Label: Caffeine-Ibuprofen; Type: OTHER; Interventions: Drug: ibuprofen, Drug: caffeine | Arm Label: Placebo-Ibuprofen/Caffeine; Type: OTHER; Interventions: Drug: ibuprofen + caffeine, Drug: placebo | Arm Label: Ibuprofen/Caffeine-Ibuprofen/Caffeine; Type: OTHER; Interventions: Drug: ibuprofen + caffeine | Arm Label: Ibuprofen-Ibuprofen; Type: OTHER; Interventions: Drug: ibuprofen | Arm Label: Caffeine-Ibuprofen/Caffeine; Type: OTHER; Interventions: Drug: caffeine, Drug: ibuprofen + caffeine | Arm Label: Placebo-Ibuprofen; Type: OTHER; Interventions: Drug: placebo, Drug: ibuprofen | Intervention Type: DRUG; Name: ibuprofen + caffeine; Assigned to Arm(s): Placebo-Ibuprofen/Caffeine | Intervention Type: DRUG; Name: ibuprofen; Assigned to Arm(s): Ibuprofen-Ibuprofen | Intervention Type: DRUG; Name: ibuprofen; Assigned to Arm(s): Caffeine-Ibuprofen | Intervention Type: DRUG; Name: caffeine; Assigned to Arm(s): Caffeine-Ibuprofen/Caffeine | Intervention Type: DRUG; Name: ibuprofen + caffeine; Assigned to Arm(s): Ibuprofen/Caffeine-Ibuprofen/Caffeine | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Placebo-Ibuprofen | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Placebo-Ibuprofen/Caffeine | Intervention Type: DRUG; Name: caffeine; Assigned to Arm(s): Caffeine-Ibuprofen | Intervention Type: DRUG; Name: ibuprofen; Assigned to Arm(s): Placebo-Ibuprofen | Intervention Type: DRUG; Name: ibuprofen + caffeine; Assigned to Arm(s): Caffeine-Ibuprofen/Caffeine
B: Arm Label: Opioid; Type: ACTIVE_COMPARATOR; Interventions: Drug: opioid-containing analgesic | Arm Label: Non-Opioid; Type: ACTIVE_COMPARATOR; Interventions: Drug: two over-the-counter analgesics | Intervention Type: DRUG; Name: opioid-containing analgesic; Assigned to Arm(s): Opioid | Intervention Type: DRUG; Name: two over-the-counter analgesics; Assigned to Arm(s): Non-Opioid
C: Arm Label: Experimental group; Type: EXPERIMENTAL; Interventions: Drug: OxyCODONE 5 Mg (milligram) Oral Tablet, Drug: Ibuprofen 600 Mg (milligram) Oral Tablet, Drug: Acetaminophen 650 MG (milligram) Oral Tablet | Arm Label: Control group; Type: ACTIVE_COMPARATOR; Interventions: Drug: OxyCODONE 5 Mg (milligram) Oral Tablet, Drug: Acetaminophen 650 MG (milligram) Oral Tablet | Intervention Type: DRUG; Name: OxyCODONE 5 Mg (milligram) Oral Tablet; Assigned to Arm(s): Control group, Experimental group | Intervention Type: DRUG; Name: Ibuprofen 600 Mg (milligram) Oral Tablet; Assigned to Arm(s): Experimental group | Intervention Type: DRUG; Name: Acetaminophen 650 MG (milligram) Oral Tablet; Assigned to Arm(s): Control group, Experimental group
D: Arm Label: Morphine; Type: EXPERIMENTAL; Interventions: Drug: Morphine | Arm Label: Ibuprofen; Type: EXPERIMENTAL; Interventions: Drug: Ibuprofen | Intervention Type: DRUG; Name: Morphine; Assigned to Arm(s): Morphine | Intervention Type: DRUG; Name: Ibuprofen; Assigned to Arm(s): Ibuprofen

Answer: A