Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Vitamin D and Omega-3 Trial (VITAL)
Brief Summary: The VITamin D and OmegA-3 TriaL (VITAL) is a randomized clinical trial in 25,871 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or omega-3 fatty acids (Omacor® fish oil, 1 gram) reduces the risk of developing cancer, heart disease, and stroke in people who do not have a prior history of these illnesses. The 5-year intervention phase (study pill-taking, median 5.3 years) has ended; post-intervention observational follow-up of study participants is ongoing.


Options:
A: Arm Label: Vitamin D + fish oil; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: vitamin D3, Drug: omega-3 fatty acids (fish oil) | Arm Label: Vitamin D + fish oil placebo; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: vitamin D3, Dietary Supplement: Fish oil placebo | Arm Label: Vitamin D placebo + fish oil; Type: ACTIVE_COMPARATOR; Interventions: Drug: omega-3 fatty acids (fish oil), Dietary Supplement: Vitamin D3 placebo | Arm Label: Vitamin D placebo + fish oil placebo; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Vitamin D3 placebo, Dietary Supplement: Fish oil placebo | Intervention Type: DIETARY_SUPPLEMENT; Name: vitamin D3; Assigned to Arm(s): Vitamin D + fish oil, Vitamin D + fish oil placebo | Intervention Type: DRUG; Name: omega-3 fatty acids (fish oil); Assigned to Arm(s): Vitamin D + fish oil, Vitamin D placebo + fish oil | Intervention Type: DIETARY_SUPPLEMENT; Name: Vitamin D3 placebo; Assigned to Arm(s): Vitamin D placebo + fish oil, Vitamin D placebo + fish oil placebo | Intervention Type: DIETARY_SUPPLEMENT; Name: Fish oil placebo; Assigned to Arm(s): Vitamin D + fish oil placebo, Vitamin D placebo + fish oil placebo
B: Arm Label: Omega-3 supplements; Type: EXPERIMENTAL; Interventions: Drug: Omega-3 supplements | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Omega-3 supplements; Assigned to Arm(s): Omega-3 supplements | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
C: Arm Label: Fish oil Active; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Omega-3 fish oil | Arm Label: Fish oil Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Corn Oil (Fish oil Placebo) | Arm Label: Losartan Active; Type: ACTIVE_COMPARATOR; Interventions: Drug: Losartan | Arm Label: Losartan Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Cellulose Based (Losartan Placebo) | Arm Label: Fish oil Active + Losartan Active; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Omega-3 fish oil, Drug: Losartan | Arm Label: Fish oil Active + Losartan Placebo; Type: OTHER; Interventions: Dietary Supplement: Omega-3 fish oil, Other: Cellulose Based (Losartan Placebo) | Arm Label: Fish oil Placebo + Losartan Active; Type: OTHER; Interventions: Drug: Losartan, Other: Corn Oil (Fish oil Placebo) | Arm Label: Fish oil Placebo + Losartan Placebo; Type: OTHER; Interventions: Other: Corn Oil (Fish oil Placebo), Other: Cellulose Based (Losartan Placebo) | Intervention Type: DIETARY_SUPPLEMENT; Name: Omega-3 fish oil; Assigned to Arm(s): Fish oil Active, Fish oil Active + Losartan Active, Fish oil Active + Losartan Placebo | Intervention Type: DRUG; Name: Losartan; Assigned to Arm(s): Fish oil Active + Losartan Active, Fish oil Placebo + Losartan Active, Losartan Active | Intervention Type: OTHER; Name: Corn Oil (Fish oil Placebo); Assigned to Arm(s): Fish oil Placebo, Fish oil Placebo + Losartan Active, Fish oil Placebo + Losartan Placebo | Intervention Type: OTHER; Name: Cellulose Based (Losartan Placebo); Assigned to Arm(s): Fish oil Active + Losartan Placebo, Fish oil Placebo + Losartan Placebo, Losartan Placebo
D: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Drug: Zodin (drug) | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Drug: Olive oil (placebo) | Intervention Type: DRUG; Name: Zodin (drug); Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: Olive oil (placebo); Assigned to Arm(s): 2

Answer: A