Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized Controlled Clinical Trial Evaluating the Efficacy of Silverlon® in Preventing Surgical Site Infection Following Colorectal Surgery
Brief Summary: This clinical study is a prospective, randomized, controlled trial of patients undergoing elective colorectal surgical procedures that receive an abdominal skin incision of at least 6 cm. Treatment with Silverlon® will be compared to standard postoperative dressings of 4x4 Gauze and paper tape. Patients will be randomized with a 1:1 treatment allocation ratio to receive either 1) Silverlon® or 2) standard postsurgical dressing. Neither the Investigators nor the participants will be blinded to the treatment modality after randomization.

Silver has long been known to have antimicrobial properties. It interacts with structural proteins and DNA, inhibiting bacterial replication and causing fatal structural changes within the cell wall. It has broad antimicrobial activities and unlike antibiotics, it is rarely associated with microbial resistance. Silverlon® is a silver-nylon dressing specifically designed for surgical wounds to prevent the development of surgical site infections. It is an easy to use product with no known microbial resistance or adverse effects. The efficacy of Silverlon® in preventing surgical site infections has been shown in several retrospective studies but as of yet has not been tested in a prospective fashion. The objective of this study is to perform a prospective, randomized, clinical trial directly comparing the incidence of surgical site infections in patients treated with Silverlon® to standard postoperative dressing following elective colorectal surgery


Options:
A: Arm Label: Silverlon Dressing; Type: EXPERIMENTAL; Interventions: Other: Silverlon | Arm Label: Standard of Care Dressing; Type: ACTIVE_COMPARATOR; Interventions: Other: Standard of Care Dressing | Intervention Type: OTHER; Name: Silverlon; Assigned to Arm(s): Silverlon Dressing | Intervention Type: OTHER; Name: Standard of Care Dressing; Assigned to Arm(s): Standard of Care Dressing
B: Arm Label: ionic silver-containing dressing; Type: EXPERIMENTAL; Interventions: Procedure: ionic silver-containing dressing | Arm Label: Mupirocin ointment application; Type: EXPERIMENTAL; Interventions: Procedure: Mupirocin ointment application | Arm Label: Conventional dressing; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: PROCEDURE; Name: ionic silver-containing dressing; Assigned to Arm(s): ionic silver-containing dressing | Intervention Type: PROCEDURE; Name: Mupirocin ointment application; Assigned to Arm(s): Mupirocin ointment application
C: Arm Label: I-ZIP Ocular Bandage; Type: EXPERIMENTAL; Interventions: Device: I-ZIP Ocular Bandage | Arm Label: Oasis 24 hour Soft Shield Collagen Corneal Shield; Type: ACTIVE_COMPARATOR; Interventions: Device: Oasis 24 Hour Soft Shield Collagen Corneal Shield | Intervention Type: DEVICE; Name: I-ZIP Ocular Bandage; Assigned to Arm(s): I-ZIP Ocular Bandage | Intervention Type: DEVICE; Name: Oasis 24 Hour Soft Shield Collagen Corneal Shield; Assigned to Arm(s): Oasis 24 hour Soft Shield Collagen Corneal Shield
D: Arm Label: Mepore Self-adhesive absorbent dressing; Type: ACTIVE_COMPARATOR; Interventions: Device: Mepore Self-adhesive absorbent dressing | Arm Label: AQUAGEL Ag Hydrofiber Wound Dressing; Type: EXPERIMENTAL; Interventions: Device: AQUAGEL Ag Hydrofiber Wound Dressing | Intervention Type: DEVICE; Name: AQUAGEL Ag Hydrofiber Wound Dressing; Assigned to Arm(s): AQUAGEL Ag Hydrofiber Wound Dressing | Intervention Type: DEVICE; Name: Mepore Self-adhesive absorbent dressing; Assigned to Arm(s): Mepore Self-adhesive absorbent dressing

Answer: A