Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Effects of Shifting Sedentary Behaviors to Light Activities on Energy Expenditure: A Randomized Controlled Trial in Sedentary Adults
Brief Summary: The main purposes of this randomized cross-over trial are to test if a 3h/day reduction of time spent in sedentary behaviour (SB) through breaking up hourly and shifting it for standing and walking behaviours would substantially increase total (TEE) and PA energy expenditure (PAEE) compared to a week of habitual prolonged SB, in male and female overweight/obese inactive (which do not attained MVPA recommendations) and sedentary desk workers. Specifically using an experiment design our main aims are: a) to determine the impact of reducing SB on TEE and PAEE; b) to analyse the independent effects of interrupting SB through breaks and the overall reduction in SB on TEE and PAEE; c) To analyse the determinants for the overall reduction in SB; d) If the changes occurred in TEE and PAEE were dependent on specific covariates.


Options:
A: Inclusion Criteria:

* Participants were required to be sedentary, between 18-65 years old, have a BMI above 25.0 kg/m2 and physical inactive (not meeting the MVPA recommendations and not exceed 6000 steps/day). In addition subjects had to be free of any major disease with a general healthy status warranted.

Exclusion Criteria:

* Taking any medication or dietary supplements that may interfere with body composition or energy expenditure regulation, performing more than 5000 steps/day and meeting actual MVPA recommendations
B: Inclusion Criteria:

1. Type 2 diabetes
2. Age 40 to 80 years at screening
3. BMI \>27\<40 kg/m2
4. Sedentary for at least 6 months
5. Treated with prescribed diet and/or OHA and insulin
6. Able to walk for 1.6 Km unaided.
7. Eligible after positive outcome of cardiac evaluation

Exclusion Criteria:

1. All patients with a history of central nervous dysfunction such as hemiparesis, myelopathies, cerebral ataxia, significant musculoskeletal deformities such as an amputation, dysmetria or scoliosis, patients with movement abnormalities or arthritis limited by pain when exercising
2. A history of clinical evidence of severe cardiovascular disease which may limit or be a contraindication for exercise
3. Clinical evidence of vestibular dysfunction
4. Angina and related symptoms
5. Postural hypotension defined as a fall in arterial blood pressure when changing position of \>20 mmHg (systole) or \>10 mmHg (diastole
6. History of plantar sores
C: Inclusion Criteria:

* Diagnosed with RA (defined by the American College Rheumatology (ACR) criteria)
* Over the age of 18 years
* Self-reported sitting time for five hours or more per day (measured by Physical Activity Scale, PAS 2.1)
* Physical function score \<2.5 (measured by Health Assessment Questionnaire, HAQ)
* Informed consent
* Understand and speak Danish
* Access to mobile phone.

Exclusion Criteria:

* Severe physical disabilities (HAQ-score \> 2.5) which would prevent them from reducing daily sitting time (e.g. use of wheelchair);
* Pregnancy
* Vigorous physical activity for more than eight hours a week (measured by PAS 2,1).
D: Inclusion Criteria:

* Kaiser Permanente Washington enrollees
* Men and women
* Age 60 - 89
* BMI 30 - 50 (calculated based on most recent height ever and most recent weight taken within previous 18 months)
* Primary care within Integrated Group Practice
* Continuously enrolled at Kaiser Permanente Washington for previous 12 months
* No record of death
* Not on the No Contact list
* Speaks and writes English
* Able to hold a conversation by phone (no hearing or other limitations)
* Self-reported sitting time of 6 hours/day or more
* Self-reported ability to stand with or without an assistive device
* Self-reported ability to walk one block with or without an assistive device
* Available for the study duration
* Able to come to Kaiser Permanente Washington Health Research Institute's research clinic for measurement visits
* Willing to wear study activity monitors

Exclusion Criteria:

* Resides in long-term care, hospice care, or skilled nursing facility (previous 12 months)
* Wheelchair bound
* Diagnosis of dementia, serious mental health disorder, or substance use disorder (previous 24 months)
* Use of an assistive device

Answer: A