Please select the eligibility criteria that correspond to the clinical trial below.
Title: Randomized Trial of Liaison Psychiatry in Primary Care
Brief Summary: This study will evaluate the effectiveness of a nurse-led case management intervention in improving disease control and depression symptoms in adults with diabetes and/or heart disease who are also depressed.


Options:
A: Inclusion Criteria:

* Diagnosis of diabetes and/or heart disease
* Poor disease control (defined as an HbA1c level of at least 8.5%, blood pressure greater than 140/90 mm Hg, LDL cholesterol greater than 130 mg/dL)
* Diagnosis of major depressive disorder

Exclusion Criteria:

* History of psychosis
* At high risk for suicide
* Cognitive impairment
* Current alcohol or substance abuse disorder
* Does not own a telephone
* Currently seeking psychiatric care
* Pregnant or breastfeeding
* Currently enrolled in a Group Health Cooperative disease management program
* Terminal illness
* Plans to leave Group Health Cooperative in less than a year
* Does not speak English
B: Inclusion Criteria:

* Patients who have experienced two weeks or more of depressed mood/ loss of interest in the past year
* Patients who have experienced one week or more of depressed mood or loss of interest in the past month
* Self defined race or ethnicity African American
* Able to give written consent

Exclusion Criteria:

* Current alcohol or drug abuse
* History of mania
* Grief reaction or bereavement within the past 2 months
* Pregnancy
* Life expectancy less than 1 year
* Non English speaking
* Current specialty mental health care (at least 2 visits in past 6 weeks and appt scheduled in future
* Plan to change health care or primary care Provider in next 12 months
* Active suicidal thoughts and plans
* Residing in US for less than 5 years
C: Inclusion Criteria:

1. Individuals with Chinese ethnicity, defined as people who self-identify as being Chinese based upon having either one or both parents being ethnic Chinese.
2. Monolingual Chinese American immigrants, defined as people who require or prefer to be interviewed in Chinese (including Cantonese, Taiwanese, Mandarin, and Toisanese dialects).
3. Men or women age 18 or older, who live in the greater Boston area.
4. Individuals who are competent to consent and have completed a written consent form.
5. Individuals who have a PCP.
6. Patients who screen positive for MDD, current according to the fourth version of the Diagnostic and Statistical Manual for Mental Disorders (DSM-IV) as diagnosed by the Mini International Neuropsychiatric Interview (MINI; Sheehan et al, 1998)
7. Individuals who are willing to receive phone interviews for monitoring of symptoms and for additional support (care management) if available.

Exclusion Criteria:

1. Patients with serious suicidal risk.
2. Patients with unstable medical illnesses requiring imminent hospitalization or rendering patients unsuitable for clinical interview.

d. Patients with comorbid severe mental disorders including:

1. Organic mental disorders.
2. Alcohol or substance abuse disorders active within the last year.
3. Schizophrenia.
4. Delusional disorder.
5. Psychotic disorders not elsewhere classified.
6. Bipolar disorder. e. Patients with history of treatment by a psychiatrist in the past 4 months.
D: Inclusion Criteria:

* Home address within 30 miles of Seattle
* Diagnosis of epilepsy (ICD-9 code 345.XX)
* Appointment in the UW REC or Neurology clinic in the past 2 years and currently enrolled in this clinic.
* Current age older than 18 years
* Diagnosis of major depression, minor depression or dysthymia
* Ability to speak/read English

Exclusion Criteria:

* Alcohol and/or substance abuse/dependence based on a score greater than 1 on 4-item validated CAGE-AID
* Cognitive impairment based on a score less than 3 on a 6-item validated cognitive screen
* Diagnosis of bipolar disorder, schizophrenia/schizoaffective disorder or other psychotic disorder
* Women who are pregnant or nursing
* Terminal medical illness
* Those currently seeing or planning to see a psychiatrist
* Those with suicidal ideation nearly every day

Answer: A