Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase 3 Randomized, Placebo-controlled, Double-blind Study of Apalutamide Plus Androgen Deprivation Therapy (ADT) Versus ADT in Subjects With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
Brief Summary: The purpose of this study is to determine if the addition of apalutamide to ADT provides superior efficacy in improving radiographic progression-free survival (rPFS) or overall survival (OS) for participants with mHSPC.


Options:
A: Arm Label: Abiraterone acetate + Prednisone + ADT; Type: EXPERIMENTAL; Interventions: Drug: Abiraterone acetate, Drug: Prednisone, Other: Androgen deprivation therapy (ADT) | Arm Label: Placebo + Androgen Deprivation Therapy (ADT); Type: PLACEBO_COMPARATOR; Interventions: Other: Androgen deprivation therapy (ADT), Drug: Abiraterone acetate Placebo, Drug: Prednisone Placebo | Intervention Type: DRUG; Name: Abiraterone acetate; Assigned to Arm(s): Abiraterone acetate + Prednisone + ADT | Intervention Type: DRUG; Name: Prednisone; Assigned to Arm(s): Abiraterone acetate + Prednisone + ADT | Intervention Type: OTHER; Name: Androgen deprivation therapy (ADT); Assigned to Arm(s): Abiraterone acetate + Prednisone + ADT, Placebo + Androgen Deprivation Therapy (ADT) | Intervention Type: DRUG; Name: Abiraterone acetate Placebo; Assigned to Arm(s): Placebo + Androgen Deprivation Therapy (ADT) | Intervention Type: DRUG; Name: Prednisone Placebo; Assigned to Arm(s): Placebo + Androgen Deprivation Therapy (ADT)
B: Arm Label: Arm A; Type: ACTIVE_COMPARATOR; Interventions: Other: Androgen Deprivation Therapy, Drug: Docetaxel | Arm Label: Arm B; Type: EXPERIMENTAL; Interventions: Drug: abiraterone acetate, Other: Androgen Deprivation Therapy, Drug: Docetaxel | Arm Label: Arm C; Type: EXPERIMENTAL; Interventions: Radiation: radiotherapy, Other: Androgen Deprivation Therapy, Drug: Docetaxel | Arm Label: Arm D; Type: EXPERIMENTAL; Interventions: Drug: abiraterone acetate, Radiation: radiotherapy, Other: Androgen Deprivation Therapy, Drug: Docetaxel | Intervention Type: DRUG; Name: abiraterone acetate; Assigned to Arm(s): Arm B, Arm D | Intervention Type: RADIATION; Name: radiotherapy; Assigned to Arm(s): Arm C, Arm D | Intervention Type: OTHER; Name: Androgen Deprivation Therapy; Assigned to Arm(s): Arm A, Arm B, Arm C, Arm D | Intervention Type: DRUG; Name: Docetaxel; Assigned to Arm(s): Arm A, Arm B, Arm C, Arm D
C: Arm Label: Apalutamide plus ADT; Type: EXPERIMENTAL; Interventions: Drug: Apalutamide, Drug: Androgen Deprivation Therapy (ADT) | Arm Label: Placebo plus ADT; Type: EXPERIMENTAL; Interventions: Drug: Placebo, Drug: Androgen Deprivation Therapy (ADT) | Intervention Type: DRUG; Name: Apalutamide; Assigned to Arm(s): Apalutamide plus ADT | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo plus ADT | Intervention Type: DRUG; Name: Androgen Deprivation Therapy (ADT); Assigned to Arm(s): Apalutamide plus ADT, Placebo plus ADT
D: Arm Label: Androgen-Deprivation Therapy and Docetaxel; Type: EXPERIMENTAL; Interventions: Drug: androgen-deprivation therapy, Drug: docetaxel | Arm Label: Androgen-Deprivation Therapy alone; Type: ACTIVE_COMPARATOR; Interventions: Drug: androgen-deprivation therapy | Intervention Type: DRUG; Name: androgen-deprivation therapy; Assigned to Arm(s): Androgen-Deprivation Therapy alone, Androgen-Deprivation Therapy and Docetaxel | Intervention Type: DRUG; Name: docetaxel; Assigned to Arm(s): Androgen-Deprivation Therapy and Docetaxel

Answer: C