Please select the eligibility criteria that correspond to the clinical trial below.
Title: Efficacy and Safety of Hourly Titrated Misoprostol Versus Vaginal Dinoprostone and Misoprostol for Cervical Ripening and Labor Induction: Randomized Clinical Trial
Brief Summary: This study evaluates the efficacy and safety of the administration of oral misoprostol versus vaginal dinoprostone and vaginal misoprostol for cervical ripening and labor induction.


Options:
A: Inclusion Criteria:

* Women over 18
* single pregnancy
* cephalic presentation
* intact membranes
* unfavorable cervix ( less than 6 Bishop )
* CTGR not reactive decelerative
* Signed informed consent by the patient.

Exclusion Criteria:

* prior Cesarean section or previous uterine surgery .
* Allergy or intolerance to any of the study drugs
* stillbirth
* uterine growth restricted fetuses
* contraindication for vaginal delivery
* Anterior placenta
* Multiparity
* moderate to severe heart disease
* hypertensive disorders of pregnancy
* Suspected chorioamnionitis
* Coagulation disorders
* history of epileptic seizures
* liver or kidney disease
* Cognitive impairment or bad knowledge of Spanish
B: Inclusion Criteria:

* Indication for labour induction
* Term pregnancy with alive fetus
* Bishop score less than six

Exclusion Criteria:

* Age less than 18 years
* Previous uterine scar
* Nonvertex presentation
* Non-reassuring fetal status
* Fetal anomalies
* Fetal growth restriction
* Genital bleeding
* Tumors, malformations and/or ulcers of vulva, perineum or vagina
C: Inclusion Criteria:

* age 18 years old or more
* singleton pregnancy at 37 weeks gestation or more
* cephalic presentation
* reassuring fetal heart rate pattern
* admission for labor induction due to medical or obstetrical conditions
* bishop score less than 6
* giving consent and having signed the consent form for this study

Exclusion Criteria:

* parity more than 3
* estimated fetal weight more than 3,500 grams
* non-reassuring fetal heart rate pattern
* having contraindication for vaginal delivery
* previous uterine scar
* suspected abruptio placenta with non-reassuring fetal heart rate pattern
* abnormal bleeding per vagina, except bloody show
* PROM
* having underlying cardiac, hepatic, or renal diseases
* having history of allergy to misoprostol or prostaglandin analogues
* cervical dilatation 3 centimeters or more
* uterine contraction 3 times or more in 10 minute
D: Inclusion Criteria:

* A medical indication for induction of labor at a gestational age between 37 +0 and 38 +6 weeks OR an elective or medical indication for induction of labor at a gestational age greater than or equal to 39 + 0 completed weeks
* Participant age of greater than or equal to14 years old
* Singleton pregnancy
* Modified Bishop score of less than or equal to 6
* Vertex fetal presentation by examination or ultrasound
* Any membrane status

Exclusion Criteria:

* Elective inductions between 37 +0 and 38 +6 completed weeks are specifically excluded
* Known intrauterine fetal demise
* Any uterine scar including prior cesarean section and myomectomy
* Known major fetal congenital malformations that may impact neonatal health
* Other evidence of fetal compromise (such as Category 2 or 3 tracing) before the induction begins
* Prior induction/cervical ripening methods utilized during this pregnancy
* Allergy to misoprostol
* Known untreated cervical infection (e.g. Gonorrhea, Chlamydia)
* Planned cesarean section due to maternal or fetal condition
* Any other contraindication to labor induction or misoprostol therapy

Answer: A