Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Neoadjuvant Docetaxel+Cisplatin and 5-fluorouracil (TPF) Followed by Radiotherapy+Concomitant Chemo or Cetuximab Versus Radiotherapy+Concomitant Chemo or Cetuximab in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck. A Randomized Phase III Factorial Study.
Brief Summary: This is a randomized multicenter open label phase III factorial trial evaluating the 3 years OS in patients with locally advanced squamous cell carcinoma of head and neck treated with locoregional treatment (radiotherapy plus concomitant chemotherapy or cetuximab) with or without neoadjuvant chemotherapy.


Options:
A: Arm Label: RT+CDDP/5-FU; Type: ACTIVE_COMPARATOR; Interventions: Drug: RT+CDDP/5-FU | Arm Label: RT+CETUXIMAB; Type: EXPERIMENTAL; Interventions: Drug: RT+CETUXIMAB | Arm Label: INDUCTION CTx(TPF)+(RT+CDDP/5-FU); Type: ACTIVE_COMPARATOR; Interventions: Drug: INDUCTION CTx(TPF)+(RT+CDDP/5-FU) | Arm Label: INDUCTION CTx(TPF)+(RT+CETUXIMAB); Type: EXPERIMENTAL; Interventions: Drug: INDUCTION CTx(TPF)+(RT+CETUXIMAB) | Intervention Type: DRUG; Name: RT+CDDP/5-FU; Assigned to Arm(s): RT+CDDP/5-FU | Intervention Type: DRUG; Name: RT+CETUXIMAB; Assigned to Arm(s): RT+CETUXIMAB | Intervention Type: DRUG; Name: INDUCTION CTx(TPF)+(RT+CDDP/5-FU); Assigned to Arm(s): INDUCTION CTx(TPF)+(RT+CDDP/5-FU) | Intervention Type: DRUG; Name: INDUCTION CTx(TPF)+(RT+CETUXIMAB); Assigned to Arm(s): INDUCTION CTx(TPF)+(RT+CETUXIMAB)
B: Arm Label: ARM A; Type: EXPERIMENTAL; Interventions: Drug: docetaxel - cisplatin - 5-fluorouracil, Radiation: radiotherapy, Drug: cetuximab | Arm Label: ARM B; Type: ACTIVE_COMPARATOR; Interventions: Drug: cisplatin, Radiation: radiotherapy | Intervention Type: DRUG; Name: docetaxel - cisplatin - 5-fluorouracil; Assigned to Arm(s): ARM A | Intervention Type: RADIATION; Name: radiotherapy; Assigned to Arm(s): ARM A | Intervention Type: DRUG; Name: cetuximab; Assigned to Arm(s): ARM A | Intervention Type: DRUG; Name: cisplatin; Assigned to Arm(s): ARM B | Intervention Type: RADIATION; Name: radiotherapy; Assigned to Arm(s): ARM B
C: Arm Label: Reduced RT + Pacitaxel/Cisplatin; Type: EXPERIMENTAL; Interventions: Drug: Paclitaxel/Cisplatin, Radiation: Reduced RT | Arm Label: Standard RT + 5-Fluorouracil/Cisplatin; Type: ACTIVE_COMPARATOR; Interventions: Drug: 5-FU/Cisplatin, Radiation: Standard RT | Intervention Type: DRUG; Name: Paclitaxel/Cisplatin; Assigned to Arm(s): Reduced RT + Pacitaxel/Cisplatin | Intervention Type: RADIATION; Name: Reduced RT; Assigned to Arm(s): Reduced RT + Pacitaxel/Cisplatin | Intervention Type: DRUG; Name: 5-FU/Cisplatin; Assigned to Arm(s): Standard RT + 5-Fluorouracil/Cisplatin | Intervention Type: RADIATION; Name: Standard RT; Assigned to Arm(s): Standard RT + 5-Fluorouracil/Cisplatin
D: Arm Label: Arm I; Type: PLACEBO_COMPARATOR; Interventions: Procedure: conventional surgery, Radiation: radiation therapy | Arm Label: Arm II; Type: ACTIVE_COMPARATOR; Interventions: Biological: cetuximab, Procedure: conventional surgery, Radiation: radiation therapy | Intervention Type: BIOLOGICAL; Name: cetuximab; Assigned to Arm(s): Arm II | Intervention Type: PROCEDURE; Name: conventional surgery; Assigned to Arm(s): Arm I, Arm II | Intervention Type: RADIATION; Name: radiation therapy; Assigned to Arm(s): Arm I, Arm II

Answer: A