Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase 4, Randomized Study to Evaluate the Safety and the Humoral and Intestinal Immunogenicity of One or Two Additional Doses of Licensed Inactivated Polio Vaccines (IPVs) in Latin American Infants Previously Vaccinated With Bivalent Oral Polio Vaccines (bOPVs)
Brief Summary: This study is a Phase IV, open, randomized, multi-center, controlled vaccine trial conducted in healthy Latin American infants, utilizing one or two supplemental doses of IPV in children previously vaccinated with 3 doses of bOPV. We will examine the impact of supplemental IPV on stool shedding and humoral immunity, as well as intra-IPV manufacturer comparability, and safety.


Options:
A: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Biological: Oral polio vaccine | Arm Label: B; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BIOLOGICAL; Name: Oral polio vaccine; Assigned to Arm(s): A
B: Arm Label: Poliorix Group; Type: EXPERIMENTAL; Interventions: Biological: Poliorix™ | Arm Label: Control Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: Oral Poliovirus vaccine | Intervention Type: BIOLOGICAL; Name: Poliorix™; Assigned to Arm(s): Poliorix Group | Intervention Type: BIOLOGICAL; Name: Oral Poliovirus vaccine; Assigned to Arm(s): Control Group
C: Arm Label: IPV/IPV/IPV/Rotarix/mOPV type 2; Type: EXPERIMENTAL; Interventions: Biological: IPV, Biological: mOPV type 2, Biological: Rotarix | Arm Label: IPV/IPV/bOPV/Rotarix/mOPV type 2; Type: ACTIVE_COMPARATOR; Interventions: Biological: IPV, Biological: bOPV, Biological: mOPV type 2, Biological: Rotarix | Arm Label: IPV/bOPV/bOPV/Rotarix/mOPV type 2; Type: ACTIVE_COMPARATOR; Interventions: Biological: IPV, Biological: bOPV, Biological: mOPV type 2, Biological: Rotarix | Intervention Type: BIOLOGICAL; Name: IPV; Assigned to Arm(s): IPV/IPV/IPV/Rotarix/mOPV type 2, IPV/IPV/bOPV/Rotarix/mOPV type 2, IPV/bOPV/bOPV/Rotarix/mOPV type 2 | Intervention Type: BIOLOGICAL; Name: bOPV; Assigned to Arm(s): IPV/IPV/bOPV/Rotarix/mOPV type 2, IPV/bOPV/bOPV/Rotarix/mOPV type 2 | Intervention Type: BIOLOGICAL; Name: mOPV type 2; Assigned to Arm(s): IPV/IPV/IPV/Rotarix/mOPV type 2, IPV/IPV/bOPV/Rotarix/mOPV type 2, IPV/bOPV/bOPV/Rotarix/mOPV type 2 | Intervention Type: BIOLOGICAL; Name: Rotarix; Assigned to Arm(s): IPV/IPV/IPV/Rotarix/mOPV type 2, IPV/IPV/bOPV/Rotarix/mOPV type 2, IPV/bOPV/bOPV/Rotarix/mOPV type 2
D: Arm Label: G1: Sanofi bOPV Control; Type: EXPERIMENTAL; Interventions: Biological: Bivalent Oral Polio Vaccine (bOPV), Biological: Monovalent Oral Polio Vaccine Type 2 (mOPV2) | Arm Label: G2: Sanofi bOPV Control; Type: EXPERIMENTAL; Interventions: Biological: Bivalent Oral Polio Vaccine (bOPV), Biological: Monovalent Oral Polio Vaccine Type 2 (mOPV2) | Arm Label: G3: Trivalent OPV Control; Type: EXPERIMENTAL; Interventions: Biological: Trivalent Oral Polio Vaccine (tOPV), Biological: Monovalent Oral Polio Vaccine Type 2 (mOPV2) | Arm Label: G4: Sanofi bOPV, Sanofi IPV; Type: EXPERIMENTAL; Interventions: Biological: Bivalent Oral Polio Vaccine (bOPV), Biological: Monovalent Oral Polio Vaccine Type 2 (mOPV2), Biological: Sanofi-Pasteur IPV (Sanofi IPV) | Arm Label: G5: Sanofi bOPV, Sanofi 2 IPV; Type: EXPERIMENTAL; Interventions: Biological: Bivalent Oral Polio Vaccine (bOPV), Biological: Monovalent Oral Polio Vaccine Type 2 (mOPV2), Biological: Sanofi-Pasteur IPV (Sanofi IPV) | Arm Label: G6: Sanofi bOPV, GSK IPV; Type: EXPERIMENTAL; Interventions: Biological: Bivalent Oral Polio Vaccine (bOPV), Biological: Monovalent Oral Polio Vaccine Type 2 (mOPV2), Biological: Glaxo SmithKline IPV (GSK IPV) | Arm Label: G7: Sanofi bOPV, GSK 2 IPV; Type: EXPERIMENTAL; Interventions: Biological: Bivalent Oral Polio Vaccine (bOPV), Biological: Monovalent Oral Polio Vaccine Type 2 (mOPV2), Biological: Glaxo SmithKline IPV (GSK IPV) | Arm Label: G8: Sanofi bOPV, SII IPV; Type: EXPERIMENTAL; Interventions: Biological: Bivalent Oral Polio Vaccine (bOPV), Biological: Monovalent Oral Polio Vaccine Type 2 (mOPV2), Biological: Serum Institute of India IPV (SII IPV) | Arm Label: G9: Sanofi bOPV, SII 2 IPV; Type: EXPERIMENTAL; Interventions: Biological: Bivalent Oral Polio Vaccine (bOPV), Biological: Monovalent Oral Polio Vaccine Type 2 (mOPV2), Biological: Serum Institute of India IPV (SII IPV) | Intervention Type: BIOLOGICAL; Name: Bivalent Oral Polio Vaccine (bOPV); Assigned to Arm(s): G1: Sanofi bOPV Control, G2: Sanofi bOPV Control, G4: Sanofi bOPV, Sanofi IPV, G5: Sanofi bOPV, Sanofi 2 IPV, G6: Sanofi bOPV, GSK IPV, G7: Sanofi bOPV, GSK 2 IPV, G8: Sanofi bOPV, SII IPV, G9: Sanofi bOPV, SII 2 IPV | Intervention Type: BIOLOGICAL; Name: Trivalent Oral Polio Vaccine (tOPV); Assigned to Arm(s): G3: Trivalent OPV Control | Intervention Type: BIOLOGICAL; Name: Monovalent Oral Polio Vaccine Type 2 (mOPV2); Assigned to Arm(s): G1: Sanofi bOPV Control, G2: Sanofi bOPV Control, G3: Trivalent OPV Control, G4: Sanofi bOPV, Sanofi IPV, G5: Sanofi bOPV, Sanofi 2 IPV, G6: Sanofi bOPV, GSK IPV, G7: Sanofi bOPV, GSK 2 IPV, G8: Sanofi bOPV, SII IPV, G9: Sanofi bOPV, SII 2 IPV | Intervention Type: BIOLOGICAL; Name: Sanofi-Pasteur IPV (Sanofi IPV); Assigned to Arm(s): G4: Sanofi bOPV, Sanofi IPV, G5: Sanofi bOPV, Sanofi 2 IPV | Intervention Type: BIOLOGICAL; Name: Glaxo SmithKline IPV (GSK IPV); Assigned to Arm(s): G6: Sanofi bOPV, GSK IPV, G7: Sanofi bOPV, GSK 2 IPV | Intervention Type: BIOLOGICAL; Name: Serum Institute of India IPV (SII IPV); Assigned to Arm(s): G8: Sanofi bOPV, SII IPV, G9: Sanofi bOPV, SII 2 IPV

Answer: D