Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomised, db, Placebo-controlled, Parallel Group Efficacy and Safety Study of BI 1356 (5mg), Administered Orally Once Daily for 18 Weeks Followed by a 34 Week Double-blind Extension Period (Placebo Patients Switched to Glimepiride) in Type 2 Diabetic Patients With Insufficient Glycaemic Control for Whom Metformin Therapy is Inappropriate (Intolerability or Contraindication)
Brief Summary: Efficacy of BI 1356 compared to placebo in patients for whom metformin therapy is inappropriate (intolerability, contraindication). The second part of the study looks at the safety of BI 1356 in this patient population with longer term treatment in comparison to a sulfonylurea drug (glimepiride)


Options:
A: Arm Label: Linagliptin; Type: EXPERIMENTAL; Interventions: Drug: Linagliptin | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Linagliptin Placebo | Arm Label: Glimepiride; Type: ACTIVE_COMPARATOR; Interventions: Drug: Glimepiride | Intervention Type: DRUG; Name: Linagliptin; Assigned to Arm(s): Linagliptin | Intervention Type: DRUG; Name: Linagliptin Placebo; Assigned to Arm(s): Placebo | Intervention Type: DRUG; Name: Glimepiride; Assigned to Arm(s): Glimepiride
B: Arm Label: metformin + glimepiride + pioglitazone + albiglutide placebo; Type: ACTIVE_COMPARATOR; Interventions: Drug: placebo to match albiglutide, Drug: metformin, Drug: glimepiride, Drug: pioglitazone | Arm Label: metformin + glimepiride + pioglitazone placebo + albiglutide; Type: EXPERIMENTAL; Interventions: Biological: albiglutide, Drug: metformin, Drug: glimepiride, Drug: placebo to match pioglitazone | Arm Label: met + glimepiride + pioglitazone placebo + albiglutide placebo; Type: ACTIVE_COMPARATOR; Interventions: Drug: placebo to match albiglutide, Drug: metformin, Drug: glimepiride, Drug: placebo to match pioglitazone | Intervention Type: DRUG; Name: placebo to match albiglutide; Assigned to Arm(s): met + glimepiride + pioglitazone placebo + albiglutide placebo, metformin + glimepiride + pioglitazone + albiglutide placebo | Intervention Type: BIOLOGICAL; Name: albiglutide; Assigned to Arm(s): metformin + glimepiride + pioglitazone placebo + albiglutide | Intervention Type: DRUG; Name: metformin; Assigned to Arm(s): met + glimepiride + pioglitazone placebo + albiglutide placebo, metformin + glimepiride + pioglitazone + albiglutide placebo, metformin + glimepiride + pioglitazone placebo + albiglutide | Intervention Type: DRUG; Name: glimepiride; Assigned to Arm(s): met + glimepiride + pioglitazone placebo + albiglutide placebo, metformin + glimepiride + pioglitazone + albiglutide placebo, metformin + glimepiride + pioglitazone placebo + albiglutide | Intervention Type: DRUG; Name: pioglitazone; Assigned to Arm(s): metformin + glimepiride + pioglitazone + albiglutide placebo | Intervention Type: DRUG; Name: placebo to match pioglitazone; Assigned to Arm(s): met + glimepiride + pioglitazone placebo + albiglutide placebo, metformin + glimepiride + pioglitazone placebo + albiglutide
C: Arm Label: placebo + pioglitazone (with or without metformin); Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Arm Label: albiglutide + pioglitazone (with or without metformin); Type: EXPERIMENTAL; Interventions: Biological: albiglutide | Intervention Type: BIOLOGICAL; Name: albiglutide; Assigned to Arm(s): albiglutide + pioglitazone (with or without metformin) | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): placebo + pioglitazone (with or without metformin)
D: Intervention Type: DRUG; Name: Rosiglitazone; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: glyburide; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: metformin; Assigned to Arm(s): N/A

Answer: A