TrialPanorama/Dataset huggingface dataset:
Please select the eligibility criteria that correspond to the clinical trial below.
Title: A Prospective, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Multinational Study Of Efficacy And Safety Of Varenicline Tartrate For Smoking Cessation
Brief Summary: To investigate safety and efficacy of varenicline tartrate in helping people quit smoking


Options:
A: Inclusion Criteria:

* Current cigarette smokers between the ages of 18 and 75 years, who are motivated to stop smoking

Exclusion Criteria:

* Patients currently suffering from depression, or have been diagnosed with depression in the last 12 months, or subjects with past or present history of psychosis, panic disorder, or bipolar disorder
* Any subject with known severe chronic obstructive pulmonary disease (COPD)
B: Inclusion Criteria:

* Diagnosis of Schizophrenia, Schizoaffective Disorder, or Bipolar Disorder
* Enrolled in services at the research site for a minimum of 3 months
* Regular smoker (approximately 10 cigarettes for the past 5 years) with a history of at least 1 quit attempt
* Fluent in English

Exclusion Criteria:

* Regular use of e-cigarettes in the past month
* Current interest/plan to quit smoking
* Regular use of nicotine replacement therapy to quit smoking or use of bupropion or varenicline to quit smoking
* Use of emergency room or hospitalization for psychiatric reasons in the past 30 days
C: Inclusion Criteria:

* resident into the Abruzzo and Lazio Region
* aged between 30 and 75 years;
* smoker of e-cigarettes (inhaling at least 50 puffs per week) containing nicotine since six or more months (E-cigarettes only Group);
* smoker of at least one traditional cigarette per day since six or more months (Traditional cigarettes only Group);
* smoker of both electronic and traditional cigarettes (at least one per day) since six or more months (Mixed Group).

Exclusion Criteria:

* illicit drug use,
* breastfeeding or pregnancy,
* major depression or other psychiatric conditions,
* severe allergies,
* active antihypertensive medication,
* angina pectoris,
* past episodes of major cardiovascular diseases (myocardial infarction, stroke/TIA, congestive heart failure, COPD, cancer of the lung, esophagus, larynx, oral cavity, bladder, pancreas, kidney, stomach, cervix, and myeloid leukemia.
D: Inclusion Criteria:

* smoking at least 10 cigarettes/day in the month prior to admission
* patient has been diagnosed with acute coronary syndrome (includes patients admitted for unstable angina or acute myocardial infarction), elective percutaneous coronary intervention, or coronary artery bypass surgery at any point in time
* motivated to stop smoking
* geographically available for follow-up visits (i.e., live within 1 hour of the study centre)

Exclusion Criteria:

* have been using NRT, Zyban (or Wellbutrin), and/or Champix for more than 72 hours
* have serious cardiac arrhythmias (e.g., tachycardia), vasospastic disease (e.g., Buerger's disease, Prinzmetal's variant angina)
* have severe renal impairment or are on dialysis
* unable to read and understand English
* patient is pregnant or breastfeeding or planning on becoming pregnant during the study period

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: A Prospective, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Multinational Study Of Efficacy And Safety Of Varenicline Tartrate For Smoking Cessation
Brief Summary: To investigate safety and efficacy of varenicline tartrate in helping people quit smoking


Options:
A: Inclusion Criteria:

* Subjects must have smoked an average of at least 15 cigarettes per day during the past year and over the month prior to the screening visit, with no period of abstinence greater than 3 months in the past year.

Exclusion Criteria:

* Subjects with clinically significant cardiovascular disease in the past 6 months.
B: Inclusion Criteria:

* Current cigarette smoker
* Averages at least 10 cigarettes/day for 5 or more years
* DSM-IV diagnosis of Nicotine Dependence
* Breath carbon monoxide \> 6 ppm
* Motivated to quit: score \> 8 on Contemplation Ladder
* Age \> 18 years

Exclusion Criteria:

* Current illicit substance use
* Other tobacco use (e.g., cigar, pipe)
* History of psychosis
* Past or current cardiovascular disease
* Impaired renal functioning
* Pregnancy
* Nursing
* Current treatment for smoking cessation
* Clinically significant depressive symptoms (CES-D \> 16)
* Current suicidal ideation
C: Inclusion Criteria:

* Male and female cigarette smokers over the age of 18 years who are not willing/able to quit smoking within the next month but who are willing to attempt to reduce their smoking to work toward a quit attempt within the next 3 months.
* Subjects must have smoked an average of at least 10 cigarettes per day during the past year and during the month prior to the screening visit, with no continuous period of abstinence greater than 3 months in the past year and who have an exhaled carbon monoxide (CO) \>10 ppm at screening.
* Subjects with mild to moderate depression or anxiety may be included if their condition is stable.

Exclusion Criteria:

* Subjects with a history of a suicide attempt or any suicidal behavior in the past two years.
* Subjects with severe depression or anxiety.
* Subjects with psychosis, panic disorder, bipolar disorder, post traumatic stress disorder (PTSD), or schizophrenia.
* Subjects with alcohol or substance abuse or dependence (except nicotine) unless in full remission for at least 12 months.
D: Inclusion Criteria:

* Current cigarette smokers between the ages of 18 and 75 years, who are motivated to stop smoking

Exclusion Criteria:

* Patients currently suffering from depression, or have been diagnosed with depression in the last 12 months, or subjects with past or present history of psychosis, panic disorder, or bipolar disorder
* Any subject with known severe chronic obstructive pulmonary disease (COPD)

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: A Prospective, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Multinational Study Of Efficacy And Safety Of Varenicline Tartrate For Smoking Cessation
Brief Summary: To investigate safety and efficacy of varenicline tartrate in helping people quit smoking


Options:
A: Inclusion Criteria:

* Current cigarette smoker
* Averages at least 10 cigarettes/day for 5 or more years
* DSM-IV diagnosis of Nicotine Dependence
* Breath carbon monoxide \> 6 ppm
* Motivated to quit: score \> 8 on Contemplation Ladder
* Age \> 18 years

Exclusion Criteria:

* Current illicit substance use
* Other tobacco use (e.g., cigar, pipe)
* History of psychosis
* Past or current cardiovascular disease
* Impaired renal functioning
* Pregnancy
* Nursing
* Current treatment for smoking cessation
* Clinically significant depressive symptoms (CES-D \> 16)
* Current suicidal ideation
B: Inclusion Criteria:

* Smokers seeking treatment
* Aged 18 and over
* Consenting to take part in the trial

Exclusion Criteria:

* Pregnant or breastfeeding
* End-stage renal disease
* Used varenicline in the past 6 months
* Unable to fill in questionnaires in English
* Current psychiatric illness
* Current serious illness including uncontrolled hypertension and recent cardiac event
* Sensitivity to varenicline currently enrolled in other research projects.
C: Inclusion Criteria:

* Subjects must have smoked an average of at least 10 cigarettes per day during the past year and over the month prior to the screening visit, with no period of abstinence greater than 3 months in the past year.

Exclusion Criteria:

* Subjects with clinically significant cardiovascular disease in the past 6 months.
D: Inclusion Criteria:

* Current cigarette smokers between the ages of 18 and 75 years, who are motivated to stop smoking

Exclusion Criteria:

* Patients currently suffering from depression, or have been diagnosed with depression in the last 12 months, or subjects with past or present history of psychosis, panic disorder, or bipolar disorder
* Any subject with known severe chronic obstructive pulmonary disease (COPD)

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Reducing Unsafe Drinking in HIV Primary Care
Brief Summary: The main aim of this study is to test an intervention to reduce unsafe drinking among HIV-positive primary care patients. The intervention consists of a brief motivational interview, which is combined with daily alcohol monitoring through the use of an interactive voice response system IVR (automated telephone system). Subjects who receive the enhanced motivational interview are expected to show greater improvements in drinking than individuals who receive the standard motivational interview or view a DVD on HIV self-care.


Options:
A: Inclusion Criteria:

* Male and females 18 years of age or older.
* Participants have had 4 or more drinks on any day in the prior 30 days assessed via standardized questions.
* Participants are referred to a study MI counselor by clinic staff as needing an intervention for drinking
* Participants agree to random assignment and provide informed consent

Exclusion Criteria:

* Participants who are currently psychotic, suicidal or homicidal.
* Participants who have definite plans to leave the greater New York metropolitan area within the study period.
* Participants who demonstrate gross cognitive impairment as evidenced on the Halstead-Reitain Trails (A).
* Participants who do not speak English or Spanish, or have hearing impairments that preclude use of the telephone.
B: Inclusion Criteria: 1

* 12-18
* speak English

Exclusion Criteria:

* cognitive impairment
C: Inclusion Criteria:

* patients 18-60 presenting to the ED for medical care
* ability to provide informed consent
* Additional criteria for intervention: past extramedical opioid use

Exclusion Criteria:

* patients who do not understand English
* prisoners
* patients classified by medical staff as a "Level 1" trauma (e.g., in need of immediate lifesaving procedures)
* patients deemed unable to provide informed consent
* patients treated in the ED for suicide attempt or sexual assault
D: Inclusion Criteria:

* Prescription drug abuse
* Prescription drug dependence
* Regular prescription drug consumption (\>60 times/last three months)

Exclusion Criteria:

* Current treatment for substance abuse problems
* Terminal illness

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Reducing Unsafe Drinking in HIV Primary Care
Brief Summary: The main aim of this study is to test an intervention to reduce unsafe drinking among HIV-positive primary care patients. The intervention consists of a brief motivational interview, which is combined with daily alcohol monitoring through the use of an interactive voice response system IVR (automated telephone system). Subjects who receive the enhanced motivational interview are expected to show greater improvements in drinking than individuals who receive the standard motivational interview or view a DVD on HIV self-care.


Options:
A: Inclusion Criteria:

* Resident of Ontario
* 19 years of age or over
* Have consumed alcohol in the one month prior to the telephone survey.
* Have consumed alcohol in the one month prior to the telephone survey.
* A score of 8 or over on the Alcohol Use Disorders Identification Test (AUDIT)
* Indicate an interest in receiving self-help materials
* Have home access to the Internet
* Are willing to participate in follow-up at six and twelve month intervals

Exclusion Criteria:

* None
B: Inclusion Criteria:

* Male and females 18 years of age or older.
* Participants have had 4 or more drinks on any day in the prior 30 days assessed via standardized questions.
* Participants are referred to a study MI counselor by clinic staff as needing an intervention for drinking
* Participants agree to random assignment and provide informed consent

Exclusion Criteria:

* Participants who are currently psychotic, suicidal or homicidal.
* Participants who have definite plans to leave the greater New York metropolitan area within the study period.
* Participants who demonstrate gross cognitive impairment as evidenced on the Halstead-Reitain Trails (A).
* Participants who do not speak English or Spanish, or have hearing impairments that preclude use of the telephone.
C: Inclusion Criteria:

* age \>21 years
* frequent alcohol use
* willing to use a cell phone and breathalyzer for 28 days
* have a valid photo ID (driver's license, passport, state ID)
* are willing to sign an off-campus property transfer form and return study equipment in four weeks

Exclusion Criteria:

* desire for, or have received, treatment for alcohol use in the past 6 months
* non-English speaking
D: Inclusion Criteria:

* membership in the included student unions

Exclusion Criteria:

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Reducing Unsafe Drinking in HIV Primary Care
Brief Summary: The main aim of this study is to test an intervention to reduce unsafe drinking among HIV-positive primary care patients. The intervention consists of a brief motivational interview, which is combined with daily alcohol monitoring through the use of an interactive voice response system IVR (automated telephone system). Subjects who receive the enhanced motivational interview are expected to show greater improvements in drinking than individuals who receive the standard motivational interview or view a DVD on HIV self-care.


Options:
A: Inclusion Criteria:

* Male and females 18 years of age or older.
* Participants have had 4 or more drinks on any day in the prior 30 days assessed via standardized questions.
* Participants are referred to a study MI counselor by clinic staff as needing an intervention for drinking
* Participants agree to random assignment and provide informed consent

Exclusion Criteria:

* Participants who are currently psychotic, suicidal or homicidal.
* Participants who have definite plans to leave the greater New York metropolitan area within the study period.
* Participants who demonstrate gross cognitive impairment as evidenced on the Halstead-Reitain Trails (A).
* Participants who do not speak English or Spanish, or have hearing impairments that preclude use of the telephone.
B: Inclusion Criteria:

* have type 2 diabetes
* have a HbA1c equal to or \> 8.0%
* must speak English, Spanish, or Cantonese.

Exclusion Criteria:

* Dementia
* Psychosis/Schizophrenia
* End Stage Renal Disease
C: Inclusion Criteria:

* age 18 years or older
* hospitalized for heart failure within the past 30 days
* access to telephone line

Exclusion Criteria:

* not expected to survive 6 months due to irreversible, life-threatening condition
* has or scheduled for cardiac transplant or LVAD
* scheduled for CABG or PCI within 90 days
* severe valvular disease
* Folstein MMSE score less than 20
* resident of a nursing home
* currently a prisoner
* does not speak English or Spanish
D: Inclusion Criteria:

* age equal to or greater than 18 years
* receiving primary care at DHS safety net clinics
* having a current diagnosis of type 2 diabetes mellitus (non-gestational).
* have a working telephone or cellular phone.

Exclusion Criteria:

* current suicidal ideation;
* inability to speak either English or Spanish;
* a score of 2 or greater on the CAGE (4M) alcohol assessment;
* having schizophrenia, schizoaffective disorder, manic-depressive, or needing lithium;
* and cognitive impairment precluding ability to give informed consent or participating in the intervention, i.e., Short Portable Mental Status Questionnaire(SPMSQ) score of 6 or more errors.

Provider and administrator inclusion criteria are: practicing or managing at one of the eight study sites; involved with diabetes or depression care

No specific exclusion criteria will be applied to providers and administrators.

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Prevention of Low Back Pain in the Military. A Randomized Clinical Trial
Brief Summary: We are studying whether specific back exercise and education programs effectively limit the development of chronic low back pain in Soldiers in the United States Army. These programs represent the current best evidence for prevention of low back pain from an exercise and education perspective. This innovative study will investigate whether a combination of evidence-based exercise and education programs effectively decreases the impact of chronic low back pain, when compared to individual evidence-based exercise and education programs, or a traditionally implemented exercise program.


Options:
A: Inclusion Criteria:

* Primary care patients aged 18 and older, of participating physicians within 5 internal medicine practices in Boston
* Registered users of patient-provider internet portal called PatientSite
* Screened positive for depression, chronic pain, or lower extremity mobility difficulty

Exclusion Criteria:

* Current treatment for screened condition by medical or surgical specialist or other appropriate licensed health professional such as a physical therapist or mental health counselor
B: Inclusion Criteria:

* Female, having wide spread pain like FMS (IPCS codes CD-10, 79.0 - coded) for at least three months ,\> 18 years, able to understand Norwegian; able to use the webenabled mobile phone.

Exclusion Criteria:

* substantial psychological problems in need of treatment with intensive psychotherapy.
C: Inclusion Criteria:

* Ages 18 - 35 years old (or emancipated minor)
* Participating in 91 W (combat medic) MOS training
* English speaking and reading

Exclusion Criteria:

* Currently seeking medical care for LBP
* Previous medical history that includes any surgery for LBP (examples include but are not limited to lumbar fusion, lumbar decompression, and lumbar discectomy)
* History of degenerative joint disease, arthritis, spine trauma or vertebral fractures, spondylolisthesis, and congenital spine disorders
* Currently unable to participate in AIT due to injury in foot, ankle, knee, hip, neck, shoulder, elbow, wrist, or hand injury.
* History of fracture (stress or traumatic) in proximal femur and/or pelvis
* Pregnancy (Note: Pregnancy will not result in termination from the study, even though it is an exclusion criteria at enrollment.)
D: Inclusion Criteria:

* arthritic condition (osteoarthritis, rheumatoid arthritis or fibromyalgia)
* internet access and ability to use computer

Exclusion Criteria:

* active treatment for cancer
* taken small group arthritis self-management program

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Prevention of Low Back Pain in the Military. A Randomized Clinical Trial
Brief Summary: We are studying whether specific back exercise and education programs effectively limit the development of chronic low back pain in Soldiers in the United States Army. These programs represent the current best evidence for prevention of low back pain from an exercise and education perspective. This innovative study will investigate whether a combination of evidence-based exercise and education programs effectively decreases the impact of chronic low back pain, when compared to individual evidence-based exercise and education programs, or a traditionally implemented exercise program.


Options:
A: Inclusion Criteria:

1. Working age up to and including 59 years.
2. Sick-listed full-time for BNP for at least 42 days and at most 730 days.
3. Able to manage tolerably well to fill in forms.

Exclusion Criteria:

1. Temporary disability pension or disability pension being paid or in preparation.
2. A primary need of action by a hospital specialist.
3. Pregnancy and diseases which would probably make rehabilitation impracticable (for example, advanced pulmonary disease).
4. Whiplash-associated disorders as a primary obstacle to working.
5. Previous rehabilitation at the rehabilitation centre.
6. Other multidisciplinary rehabilitation going on or planned.
B: Inclusion Criteria:

* Ages 18 - 35 years old (or emancipated minor)
* Participating in 91 W (combat medic) MOS training
* English speaking and reading

Exclusion Criteria:

* Currently seeking medical care for LBP
* Previous medical history that includes any surgery for LBP (examples include but are not limited to lumbar fusion, lumbar decompression, and lumbar discectomy)
* History of degenerative joint disease, arthritis, spine trauma or vertebral fractures, spondylolisthesis, and congenital spine disorders
* Currently unable to participate in AIT due to injury in foot, ankle, knee, hip, neck, shoulder, elbow, wrist, or hand injury.
* History of fracture (stress or traumatic) in proximal femur and/or pelvis
* Pregnancy (Note: Pregnancy will not result in termination from the study, even though it is an exclusion criteria at enrollment.)
C: Inclusion Criteria:

* Daily LBP, dominating over possible pain in leg or other joints/muscles
* Pain og \> 4 (scale 0-10) for more than 4 months

Exclusion Criteria:

* Cancer, inflammatory disease, previous back surgery, pregnancy
D: Inclusion Criteria:

1. Low Back Pain lasting more than 12 weeks with or with out pain radiating into the leg(s)
2. Age 18 - 60 years

Exclusion Criteria:

1. Serious spinal pathology

   1. Malignancy
   2. Osteoporosis,
   3. Fresh vertebral fracture
   4. Newly operation on the back
   5. Stenosis of the lumbar spine
   6. Unstable spondylolistesis
   7. Infections in the back
2. Neurological dysfunction of the thoracic or abdominal muscles
3. Pregnancy/breastfeeding
4. Mental illness
5. Health conditions which prohibit intensive training.
6. Languish problems/ dyslexia

Answer: B