Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Double Blind Cross-over Randomized Controlled Trial Comparing Letrozole Versus Clomifene Citrate for Ovulation Induction in Women With Polycystic Ovarian Syndrome
Brief Summary: The primary aim of the study is to assess the efficacy of letrozole as an ovulation induction agent and to test the hypothesis that letrozole will generate better pregnancy rates with fewer multiple pregnancies and higher live birth rate than the current standard agent, clomifene citrate in anovular infertile women with polycystic ovarian syndrome.


Options:
A: Arm Label: Clomiphene citrate; Type: ACTIVE_COMPARATOR; Interventions: Drug: Clomifene citrate | Arm Label: Letrozole; Type: ACTIVE_COMPARATOR; Interventions: Drug: Letrozole | Intervention Type: DRUG; Name: Letrozole; Assigned to Arm(s): Letrozole | Intervention Type: DRUG; Name: Clomifene citrate; Assigned to Arm(s): Clomiphene citrate
B: Arm Label: arm 1:letrozole-pioglitazone -metformin group; Type: ACTIVE_COMPARATOR; Interventions: Drug: induction of ovulation using letrozole-pioglitazone-metformin, Radiation: transvaginal ultrasound, Other: body mass index (BMI) calculation, Other: day 3: follicle stimulating hormone (FSH), luteinizing hormone (LH), thyroid stimulating hormone (TSH), total testosterone, Other: pretreatment blood urea and serum creatinine, Other: serum estradiol (E2) on day 12, Other: serum progesterone on day 21, Other: blood urea and serum creatinine every month | Arm Label: arm 2: clomiphene citrate-pioglitazone-metformin; Type: ACTIVE_COMPARATOR; Interventions: Drug: induction of ovulation using clomiphene citrate-pioglitazone-metformin, Radiation: transvaginal ultrasound, Other: body mass index (BMI) calculation, Other: day 3: follicle stimulating hormone (FSH), luteinizing hormone (LH), thyroid stimulating hormone (TSH), total testosterone, Other: pretreatment blood urea and serum creatinine, Other: serum estradiol (E2) on day 12, Other: serum progesterone on day 21, Other: blood urea and serum creatinine every month | Intervention Type: DRUG; Name: induction of ovulation using letrozole-pioglitazone-metformin; Assigned to Arm(s): arm 1:letrozole-pioglitazone -metformin group | Intervention Type: DRUG; Name: induction of ovulation using clomiphene citrate-pioglitazone-metformin; Assigned to Arm(s): arm 2: clomiphene citrate-pioglitazone-metformin | Intervention Type: RADIATION; Name: transvaginal ultrasound; Assigned to Arm(s): arm 1:letrozole-pioglitazone -metformin group, arm 2: clomiphene citrate-pioglitazone-metformin | Intervention Type: OTHER; Name: body mass index (BMI) calculation; Assigned to Arm(s): arm 1:letrozole-pioglitazone -metformin group, arm 2: clomiphene citrate-pioglitazone-metformin | Intervention Type: OTHER; Name: day 3: follicle stimulating hormone (FSH), luteinizing hormone (LH), thyroid stimulating hormone (TSH), total testosterone; Assigned to Arm(s): arm 1:letrozole-pioglitazone -metformin group, arm 2: clomiphene citrate-pioglitazone-metformin | Intervention Type: OTHER; Name: pretreatment blood urea and serum creatinine; Assigned to Arm(s): arm 1:letrozole-pioglitazone -metformin group, arm 2: clomiphene citrate-pioglitazone-metformin | Intervention Type: OTHER; Name: serum estradiol (E2) on day 12; Assigned to Arm(s): arm 1:letrozole-pioglitazone -metformin group, arm 2: clomiphene citrate-pioglitazone-metformin | Intervention Type: OTHER; Name: serum progesterone on day 21; Assigned to Arm(s): arm 1:letrozole-pioglitazone -metformin group, arm 2: clomiphene citrate-pioglitazone-metformin | Intervention Type: OTHER; Name: blood urea and serum creatinine every month; Assigned to Arm(s): arm 1:letrozole-pioglitazone -metformin group, arm 2: clomiphene citrate-pioglitazone-metformin
C: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Drug: Clomiphene citrate | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Drug: Letrozole | Intervention Type: DRUG; Name: Clomiphene citrate; Assigned to Arm(s): A | Intervention Type: DRUG; Name: Letrozole; Assigned to Arm(s): B
D: Arm Label: Pre-treatment acupuncture + letrozole; Type: EXPERIMENTAL; Interventions: Other: Pre-treatment acupuncture, Drug: Letrozole | Arm Label: Letrozole; Type: ACTIVE_COMPARATOR; Interventions: Drug: Letrozole | Intervention Type: OTHER; Name: Pre-treatment acupuncture; Assigned to Arm(s): Pre-treatment acupuncture + letrozole | Intervention Type: DRUG; Name: Letrozole; Assigned to Arm(s): Letrozole, Pre-treatment acupuncture + letrozole

Answer: A