Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effect of 2 Versus 3 Pneumococcal Conjugate Vaccinations Prevnar on Nasopharyngeal Carriage, Transmission and Herd-immunity;a Randomized, Controlled Study
Brief Summary: Two( 2) or three (3) instead of four vaccinations before the age of 6 months with pneumococcal conjugate vaccine are presumed to protect children against invasive pneumococcal disease like meningitis, at least on the short term till 18-24 months of age. The current hypothesis in this study is 2 or 3 vaccinations will protect against IPD but will not alter pneumococcal nasopharyngeal carriage in infants, and consequently not change pneumococcal transmission and induce no herd-immunity. Furthermore, antibody development and memory may benefit from carriage of vaccine type S. pneumoniae


Options:
A: Arm Label: 10Pn3+1-6W-6M/053 Group; Type: EXPERIMENTAL; Interventions: Biological: Pneumococcal conjugate vaccine Synflorix (GSK1024850A) | Arm Label: 10Pn2+1-6W-6M/053 Group; Type: EXPERIMENTAL; Interventions: Biological: Pneumococcal conjugate vaccine Synflorix (GSK1024850A) | Arm Label: Ctrl3+1-6W-6M/053 Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: GSK Biologicals' Engerix TM vaccine (Hepatitis B vaccine) | Arm Label: Ctrl2+1-6W-6M/053 Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: GSK Biologicals' Engerix TM vaccine (Hepatitis B vaccine) | Arm Label: 10Pn7-11M/053 Group; Type: EXPERIMENTAL; Interventions: Biological: Pneumococcal conjugate vaccine Synflorix (GSK1024850A) | Arm Label: Ctrl7-11M/053 Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: GSK Biologicals' Engerix TM vaccine (Hepatitis B vaccine) | Arm Label: 10Pn12-18M/053 Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: Pneumococcal conjugate vaccine Synflorix (GSK1024850A) | Arm Label: Ctrl12-18M/053 Group; Type: EXPERIMENTAL; Interventions: Biological: GSK Biologicals' Havrix TM vaccine (Hepatitis A vaccine) | Intervention Type: BIOLOGICAL; Name: Pneumococcal conjugate vaccine Synflorix (GSK1024850A); Assigned to Arm(s): 10Pn12-18M/053 Group, 10Pn2+1-6W-6M/053 Group, 10Pn3+1-6W-6M/053 Group, 10Pn7-11M/053 Group | Intervention Type: BIOLOGICAL; Name: GSK Biologicals' Engerix TM vaccine (Hepatitis B vaccine); Assigned to Arm(s): Ctrl2+1-6W-6M/053 Group, Ctrl3+1-6W-6M/053 Group, Ctrl7-11M/053 Group | Intervention Type: BIOLOGICAL; Name: GSK Biologicals' Havrix TM vaccine (Hepatitis A vaccine); Assigned to Arm(s): Ctrl12-18M/053 Group
B: Arm Label: Synflorix + Infanrix hexa Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: GSK Biologicals´ Pneumococcal Conjugate Vaccine GSK1024850A (Synflorix™), Biological: Infanrix™ hexa. | Arm Label: Synflorix + Pediacel Group; Type: EXPERIMENTAL; Interventions: Biological: GSK Biologicals´ Pneumococcal Conjugate Vaccine GSK1024850A (Synflorix™), Biological: Pediacel™ | Arm Label: Prevenar + Pediacel Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: Pediacel™, Biological: Prevenar™ | Intervention Type: BIOLOGICAL; Name: GSK Biologicals´ Pneumococcal Conjugate Vaccine GSK1024850A (Synflorix™); Assigned to Arm(s): Synflorix + Infanrix hexa Group, Synflorix + Pediacel Group | Intervention Type: BIOLOGICAL; Name: Infanrix™ hexa.; Assigned to Arm(s): Synflorix + Infanrix hexa Group | Intervention Type: BIOLOGICAL; Name: Pediacel™; Assigned to Arm(s): Prevenar + Pediacel Group, Synflorix + Pediacel Group | Intervention Type: BIOLOGICAL; Name: Prevenar™; Assigned to Arm(s): Prevenar + Pediacel Group
C: Arm Label: Synflorix Group; Type: EXPERIMENTAL; Interventions: Biological: Pneumococcal conjugate vaccine GSK1024850A, Biological: Havrix, Biological: Infanrix hexa, Biological: GSK Biologicals' DTPa-IPV/Hib vaccine | Arm Label: Control Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: Havrix, Biological: Engerix-B, Biological: GSK Biologicals' DTPa-IPV/Hib vaccine | Intervention Type: BIOLOGICAL; Name: Pneumococcal conjugate vaccine GSK1024850A; Assigned to Arm(s): Synflorix Group | Intervention Type: BIOLOGICAL; Name: Havrix; Assigned to Arm(s): Control Group, Synflorix Group | Intervention Type: BIOLOGICAL; Name: Engerix-B; Assigned to Arm(s): Control Group | Intervention Type: BIOLOGICAL; Name: Infanrix hexa; Assigned to Arm(s): Synflorix Group | Intervention Type: BIOLOGICAL; Name: GSK Biologicals' DTPa-IPV/Hib vaccine; Assigned to Arm(s): Control Group, Synflorix Group
D: Arm Label: 2-dose; Type: EXPERIMENTAL; Interventions: Biological: PCV7 | Arm Label: 2+1-dose; Type: EXPERIMENTAL; Interventions: Biological: PCV7 | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BIOLOGICAL; Name: PCV7; Assigned to Arm(s): 2-dose | Intervention Type: BIOLOGICAL; Name: PCV7; Assigned to Arm(s): 2+1-dose

Answer: D