Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effects of Transcranial DC Stimulation Coupled With Constraint Induced Movement Therapy on Motor Function in Stroke Patients
Brief Summary: The purpose of this study is to determine whether a painless and noninvasive procedure called transcranial direct current stimulation (tDCS) combined with a method of physical therapy called constraint-induced movement therapy improves motor function in patients with chronic stroke. Research in healthy subjects has shown that when tDCS is combined with motor learning tasks, there is an increase in learning as compared to motor learning tasks only. The tDCS procedure sessions will be compared to sham (fake) procedure sessions, which is also called placebo stimulation. This study is double blind, which means neither the subjects nor researchers analyzing motor function will know if participants are receiving real tDCS stimulation or placebo. Only the person performing the procedure will know which one participants are receiving. Only by comparing the tDCS procedure to a sham (placebo) procedure can we understand if the tDCS actually improves motor function.

We hypothesize that tDCS will enhance the effects of constraint-induced movement therapy on motor recovery in chronic stroke patients.


Options:
A: Arm Label: Sham tDCS and motor training: sham comparator; Type: SHAM_COMPARATOR; Interventions: Device: Sham tDCS | Arm Label: Anodal tDCS and motor training: experimental; Type: EXPERIMENTAL; Interventions: Device: anodal tDCS (device) Eldith DC-Stimulator | Intervention Type: DEVICE; Name: anodal tDCS (device) Eldith DC-Stimulator; Assigned to Arm(s): Anodal tDCS and motor training: experimental | Intervention Type: DEVICE; Name: Sham tDCS; Assigned to Arm(s): Sham tDCS and motor training: sham comparator
B: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Device: Active transcranial Direct Current Stimulation / Constraint Induced Movement Therapy | Arm Label: 2; Type: SHAM_COMPARATOR; Interventions: Device: Sham transcranial Direct Current Stimulation / Constraint Induced Movement Therapy | Intervention Type: DEVICE; Name: Active transcranial Direct Current Stimulation / Constraint Induced Movement Therapy; Assigned to Arm(s): 1 | Intervention Type: DEVICE; Name: Sham transcranial Direct Current Stimulation / Constraint Induced Movement Therapy; Assigned to Arm(s): 2
C: Arm Label: sham-tDCS + UE robot-assisted therapy; Type: SHAM_COMPARATOR; Interventions: Device: sham-tDCS + UE robot-assisted therapy | Arm Label: real-tDCS + UE robot-assisted therapy; Type: EXPERIMENTAL; Interventions: Device: real-tDCS + UE robot-assisted therapy | Intervention Type: DEVICE; Name: real-tDCS + UE robot-assisted therapy; Assigned to Arm(s): real-tDCS + UE robot-assisted therapy | Intervention Type: DEVICE; Name: sham-tDCS + UE robot-assisted therapy; Assigned to Arm(s): sham-tDCS + UE robot-assisted therapy
D: Arm Label: Sham; Type: SHAM_COMPARATOR; Interventions: Device: Sham | Arm Label: Conventional Paired tDCS; Type: ACTIVE_COMPARATOR; Interventions: Device: Conventional Paired tDCS | Arm Label: Conventional Unpaired tDCS; Type: ACTIVE_COMPARATOR; Interventions: Device: Conventional Unpaired tDCS | Arm Label: Late LTP-like Plasticity tDCS; Type: EXPERIMENTAL; Interventions: Device: Late LTP-like Plasticity tDCS | Intervention Type: DEVICE; Name: Sham; Assigned to Arm(s): Sham | Intervention Type: DEVICE; Name: Conventional Paired tDCS; Assigned to Arm(s): Conventional Paired tDCS | Intervention Type: DEVICE; Name: Conventional Unpaired tDCS; Assigned to Arm(s): Conventional Unpaired tDCS | Intervention Type: DEVICE; Name: Late LTP-like Plasticity tDCS; Assigned to Arm(s): Late LTP-like Plasticity tDCS

Answer: B