Please select the eligibility criteria that correspond to the clinical trial below.
Title: Enhancing Conservative Treatment for Urge Incontinence
Brief Summary: The primary objective of this project is to evaluate whether enhancing drug therapy with components of behavioral training, including pelvic floor muscle rehabilitation, results in better outcomes than drug therapy alone for urge incontinence in community-dwelling women.


Options:
A: Inclusion Criteria:

* complaints of urinary leakage \> 3 in last month (not stress incontinence)
* functionally independent subjects

Exclusion Criteria:

* urinary tract infection
* urogenital prolapse
* unstable diabetes
* neurological or psychiatric disease
* narrow angle glaucoma
* after colposuspension or sling surgery
* Mini Mental State Examination \<24
B: Inclusion Criteria:

* Pre-pregnancy body mass index of 28 or more
* 18 years or more
* singleton live fetus at the routine ultrasound scan

Exclusion Criteria:

* high risk for preterm labor or diseases that could interfere with participation
C: Inclusion Criteria:

* Urgency urinary incontinence or mixed urinary incontinence, established via telephone interview
* Urinary leakage twice a week or more often
* Duration of urinary leakage with urgency for at least 12 months
* Ability to read and write Swedish
* Asset to a smartphone (minimum iOS\* 8.0 for Apple, 4.0.3 for Androids
* Possibility to send and receive email and asset to printer
* Motivation and time to perform a 15 weeks long treatment programme with focus on self-care and behavioural training (mainly pelvic floor muscle training and bladder training).
* Accept to be randomized to one of two groups; a treatment app group or an information app Group

  * iOS=mobile operating system including iPhone, iPad and iPod touch

Exclusion Criteria:

* Participation in our previous internet or smartphone study
* Ongoing pregnancy
* Former incontinence surgery
* Known malignancy in lower abdomen
* Unassessed difficulties in emptying bladder
* Visual blood in urine
* Three or more urinary tract infections during the last 12 months
* One or more pyelonephritis during the last three years
* Painful micturition
* Painful urgency
* Intermenstrual bleeding
* Neurological disease such as multiple sclerosis or Parkinsons disease
* Previous stroke
* Diabetes mellitus
* Maximum voided volume of less than 150 ml (micturition chart)
* Regular use of any mobile app for pelvic floor muscle training during the last month
* Usage of antimuscarinic drugs or mirabegron during the last month
D: Inclusion Criteria:

Participants in this study were ambulatory, community-dwelling women (veterans and nonveterans) with persistent urge or predominantly urge incontinence.

Participants must:

1. Be ambulatory.
2. Be able to come to the clinic for treatment.
3. Report urge incontinence.
4. Report incontinence occurring at least twice per week on average.
5. Report incontinence persisting for at least three months.
6. Not have received behavioral therapy in the University of Alabama at Birmingham (UAB) Continence Clinic or Department of Veterans Affairs (VA) Continence Clinic.
7. In the clinical interview, the subject must report involuntary loss of urine associated with a strong desire to void and that the condition has persisted for at least three months.
8. At least two urge accidents on the 7-day baseline bladder diary, and the number of urge accidents must exceed the number of other types of accidents.
9. On urodynamic evaluation, there must be cystometric evidence of bladder dysfunction, either: detrusor instability or maximal cystometric capacity is less than 400 ml.

Exclusion Criteria:

1. Continual leakage.
2. Urinary tract infection (defined as growth of greater than 10,000 colonies per ml of a urinary pathogen on urine culture).
3. Fecal impaction.
4. Uncontrolled metabolic problem.
5. Post-void residual volume \> 150 ml.
6. Hematuria on microscopic examination in the absence of infection. A urologic consultation will be recommended and enrollment will depend on agreement between the urologist and geriatrician (co-PI) that entry into treatment protocol is not contraindicated.
7. Severe uterine prolapse (prolapse reaching the vaginal introitus).
8. Decompensated congestive heart failure, diagnosed by history or physical exam.
9. Impaired mental status. (\<24 on Folstein's Mini-Mental State Exam).
10. Uncontrolled narrow angle glaucoma.
11. Gastric retention (by medical history).
12. Hypersensitivity to oxybutynin.
13. Current use of anticholinergic agents for detrusor instability. Subjects on these medications will be asked to discontinue them for the duration of the study. Evaluation will be delayed until the drug(s) have been discontinued for 2 weeks.
14. If on diuretic, dose stable for less than three months.

Answer: D