Please select the eligibility criteria that correspond to the clinical trial below.
Title: Diet and Prevention of Ischemic Heart Disease: a Translational Approach
Brief Summary: The objective of this study is to test the effect of substitution dietary guidelines that are specifically aimed at the prevention of ischemic heart disease (IHD) on the dietary intake in the general Danish population.


Options:
A: Inclusion Criteria:

* healthy men and women aged 30 to 65 years who has one or more self-assessed ischemic heart disease risk factors at screening: physical inactivity, overweight or obese (BMI ≥ 25/m2 ), waist circumference (≥ 80 cm for women, ≥ 94 cm for men). In addition, the participants should have the motivation and willingness to be randomized to any of the three groups, and to do their best to follow the given protocol .

Exclusion Criteria:

* no internet access or no access to a computer, smoking, pregnancy, or breast-feeding or planning to become pregnant within the next 12 months, a history of cardiovascular disease, type 2 diabetes, chronic disease / disorders that may affect the results of the study, substance abuse within the past 12 months, regular alcohol consumption \> 21 units / week for men or \> 14 units/ week for women, allergy or intolerance to food groups in the dietary guidelines, supplements with mega doses of nutrients that can have potential impact on ischemic heart disease risk markers (eg . fish oils).
B: Inclusion Criteria:

* Subject enrolled in the cohort Nutriep assembled in 2005-2007
* Moderate or severe NAFLD

Exclusion Criteria:

* Middle NAFLD
* Not enrolled in the Nutriep cohort
* Pregnancy
C: Inclusion Criteria:

* Age: 16-35 years
* Body mass index (kg/m2): 28-36

Exclusion Criteria:

* Body weight fluctuations \> 3 kg over the previous 2 months
* Smoking

Presence of:

* Cardiovascular diseases, cancer tumours, kidney or lever diseases, infections or endocrinological diseases, malabsorption disorders
* Systolic blood pressure \> 180 mmHg and/or diastolic blood pressure \> 100 mmHg
* Hypercholesterolemia with changes in pharmacological treatment within the last 2 months
* Regular use of medicine other than birth pills, any psychological disorders, known or presumed abuse of alcohol, allergies to any food, special diets (eg. vegetarian) or particular dislikes
* Pregnancy, lactating or planning pregnancy within 18 month from enrolment
D: Inclusion criteria:

* Students in Zhejiang University or working stuff in the Chinese PLA General Hospital
* 18 ≤ age ≤ 35
* Body Mass Index \< 28\*
* Are willing to eat all of the study foods even when full
* Are willing to eat only foods provided
* Are willing to avoid strenuous activity during the 6-mo intervention Exclusion criteria：
* Systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg
* Total cholesterol ≥ 239 mg/dL
* Low-density lipoprotein cholesterol ≥ 159 mg/dL
* Triglycerides ≥ 199 mg/dL
* Blood glucose ≥ 110 mg/dL
* Change in body weight exceeding ± 10% during the prior year
* Energy intake is too low or too high
* Unwillingness or special requirement for diet that could not be modified
* Poor adherence during the recruiting meeting or unsatisfactory completion of keeping food diary or filling questionnaire at any time before randomization
* Eating disorder or any psychosocial or scheduling factors that could impede study outcomes
* Have a history of diagnosed CVD, diabetes, cancer or inflammatory diseases
* Have a history of a mental illness
* Have diagnosed endocrine, pulmonary or hematological disease
* Have diagnosed bowel disease or malabsorption that would prevent the participants from complying with the dietary restrictions of the feeding trial
* Renal or liver insufficiency
* Other chronic disease thought to interfere with the effect of the diet or with participation or adherence
* Current use of supplements or anti-inflammation medications or medications affecting glucose, lipid metabolism and blood pressure
* Smoking or alcoholic beverage intake \>1 times per week
* Current or planned pregnancy prior to end of study, or breast-feeding
* Irregular menstrual cycles
* Have birth control medication

Answer: A