Please select the eligibility criteria that correspond to the clinical trial below.
Title: MOBILE Trial. Mechanical and Oral Antibiotic Bowel Preparation Versus no Bowel preparatIon for eLEctive Colectomy - a Multicenter, Prospective, Randomized, Controlled Trial.
Brief Summary: Enchanced recovery after surgery (ERAS) protocols aim to provide safer and quicker recovery postoperatively. One of the elements in ERAS protocols is that bowel is not prepared before colorectal surgery. However, several recent retrospective register studies have suggested that mechanical bowel preparation combined to oral antibiotics before colectomy reduces complications compared to no preparation at all. This trial compares these two strategies to find out whether complications can indeed be reduced by mechanically preparing the bowel with oral antibiotics.


Options:
A: Inclusion Criteria:

* Scheduled VA adult elective colorectal surgery patient

Exclusion Criteria:

* Non VA adults, emergent colorectal surgery, scheduled multiple surgery procedures,pts with other infections being treated
B: Inclusion criteria:

* Summary: All consecutive patients undergoing colorectal resection should be included.
* Age: Age 18 years or above.
* The general health condition of the patient permits general anesthesia (ASA- classification I-III).
* Absence of allergy to the oral antibiotics employed
* Timing: Elective procedures.
* Technique: Open, laparoscopic, laparoscopic-assisted or laparoscopic converted to open.
* Returns to theatre: Each patient should only be included in the study once. Return to theatre during the same admission or follow up should be collected as a complication.
* Included procedures: Any colorectal resection (See Appendix B).
* Mechanical Bowel Preparation: Any mechanical bowel preparation (as indicated by each centre).

Exclusion criteria:

* Emergency procedures
* Appendicectomy (unless procedure involves a right hemicolectomy)
* Primarily urological/gynecological or vascular procedure - e.g. ileal conduit, Hartmann's during ovarian surgery, resection during abdominal aortic aneurysm repair.
* Diagnostic laparotomy/laparoscopy without intestinal resection.
* Surgery involving multi-visceral surgery - e.g. pelvic exenteratio
* Controindication for mechanical preparation
* Allergy to used drugs (neomycin sulfate, amoxicillin-clavulanic acid)
* Patients who refuse to participate in the study
* Patients with intra-abdominal sepsis before surgery (abscess).
* Patients who received antibiotics for any reason within two weeks prior to surgery.
* Patients who do not comply strictly with the assigned prophylaxis regimen.
* Patients who cannot be followed at least 4 weeks after surgery.
C: Inclusion Criteria:

* Patients undergoing colon resection

Exclusion Criteria:

* Emergency surgery needed
* Bowel obstruction
* Colonoscopy scheduled to be undertaken peroperatively
* Other reason indicating mechanical preparation or contradicting it
* Allergy to used drugs (PEG, neomycin, metronidazole)
D: Inclusion Criteria:

* Elective colon and rectal cancer surgery with primary anastomosis
* Or elective colorectal surgery for suspected carcinoma
* No evidence of distant metastases (preoperative CT-abdomen and X-thorax or CTthorax)
* Procedure either with or without diverting stoma
* Both laparoscopic and open surgery
* Informed consent
* Aged 18 years or older

Exclusion Criteria:

* Previous colorectal malignancy
* Current malignancy which is now undergoing treatment
* Inflammatory bowel disease (Crohn's disease or ulcerative colitis)
* Previous surgery for diverticular disease
* Performance status ASA 4 or higher (American Society for Anaesthesiologists)
* Expected adverse reactions/allergies for study medication
* Prednisone use \> 5 mg per day
* Familial adenomatous polyposis coli (FAP; Lynch syndrome), Hereditary Non Polyposis Colorectal Cancer (HNPCC)
* Mental disorder/unable to give informed consent
* Pregnancy

Answer: C