Please select the eligibility criteria that correspond to the clinical trial below.
Title: Very Intensive Variable Repetitive AmbulatioN Training
Brief Summary: The overall objective of this subproject is to evaluate the individual and paired contributions of intensity and variability of stepping training on lower extremity (LE) function, health and community participation in patients with chronic hemiparesis post-stroke.


Options:
A: Inclusion Criteria:

* subacute (\<6 months) stroke
* 18-75 years old
* history of history of unilateral, supratentorial, ischemic or hemorrhage stroke
* able to walk 10m without physical assistance
* gait speed less than or equal to .8m/s
* medical clearance

Exclusion Criteria:

* significant cardiorespiratory or metabolic disease that may limit exercise participation
* weight limit \> 250 lbs (limit of most counter-weight safety systems)
* history of previous orthopedic or neurological conditions which may impair walking.
* women of childbearing potential will not be excluded, although women who are pregnant will be excluded due to potential forces at trunk from the harness applied at the waist.
* subjects with scores \< 23 on the Mini Mental Status Exam

  * Exclusion for transcranial magnetic stimulation (TMS):
* pacemaker
* metal implants in the head region
* history of epilepsy or seizures
* skull fractures or skull deficits
* concussion within the last 6 months
* unexplained recurring headaches
* medications that lower seizure threshold
* pregnancy

  * Exclusion for the MRI:
* aneurysm clip or coil
* metal or wire implants
* heart valve prosthesis
B: Inclusion Criteria:

1. 3 to 24 months onset from a first-ever unilateral stroke
2. an initial UL subsection of the Fugl-Meyer Assessment score of 18 to 56 indicating moderate to severe and moderate UL movement impairment
3. no excessive spasticity in any of the joints of the affected UL (shoulder, elbow, wrist, fingers)
4. be able to follow study instructions and perform study tasks
5. without upper limb fracture within 3 months
6. lack of participation in any experimental rehabilitation or drug studies during the study period
7. willing to provide written informed consent

Exclusion Criteria:

1. subjects exhibiting physician-determined major medical problems or poor physical conditions that would interfere with participation
2. subjects with excessive pain in any joint that might limit participation
C: Inclusion Criteria:

* history unilateral stroke \> 6 months duration
* walks without physical assistance at speeds \< 1.0 m/s

Exclusion Criteria:

* no other cardiopulmonary, metabolic, neurological orthopedic injury that may contribute to walking outcomes
D: Inclusion Criteria:

1. First-ever stroke with the onset 10-90 days prior to the enrollment
2. Age: 20-80y
3. With a hemiplegic upper extremity with Brunnstrom stage in I\~IV
4. Able to understand simple orders (1-step orders, such as "raise your hand, touch your head....)
5. Totally independent in activity of daily life before the onset of stroke

Exclusion Criteria:

1. Incompliance to the assessments or interventions due to unstable medical condition, abnormal cognition, or other conditions.
2. Stroke of brainstem or cerebellum
3. Had received craniotomy or ventriculoperitoneal shunting
4. Needs of orthoses in walking before the onset of stroke
5. Had had motor dysfunctions (eg, amputation, cerebral palsy, poliomyelitis or other neuromuscular diseases) before the stroke.
6. Intracranial hemorrhage caused by artereovenous malformation, aneurysm, or tumor
7. Able to walk independently for more than 50 meters.

Answer: C