TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Long-Term Integrated Telerehabilitation of COPD Patients. A Multi-Center Randomized Controlled Trial
Brief Summary: This research project aims to conduct a three-arm multi-center randomized controlled trial (RCT) on an innovative telerehabilitation intervention for patients with chronic obstructive pulmonary disease (COPD). The overall purpose of the RCT is to demonstrate whether long-term integrated telerehabilitation involving exercise training at home, telemonitoring, and education/self-management will prevent hospital readmissions, thus reducing healthcare costs, for patients with COPD, and will improve patient status and quality of life.


Options:
A: Arm Label: Minimal intervention; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Minimal intervention | Arm Label: Enhanced intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Enhanced Intervention | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Minimal intervention; Assigned to Arm(s): Minimal intervention | Intervention Type: BEHAVIORAL; Name: Enhanced Intervention; Assigned to Arm(s): Enhanced intervention
B: Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Bundle; Type: EXPERIMENTAL; Interventions: Behavioral: Bundle tool | Intervention Type: BEHAVIORAL; Name: Bundle tool; Assigned to Arm(s): Bundle
C: Arm Label: Telerehabilitation; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise training at home, Behavioral: Telemonitoring and education/self-management | Arm Label: Unsupervised exercise training at home; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise training at home | Arm Label: Usual care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Exercise training at home; Assigned to Arm(s): Telerehabilitation, Unsupervised exercise training at home | Intervention Type: BEHAVIORAL; Name: Telemonitoring and education/self-management; Assigned to Arm(s): Telerehabilitation
D: Arm Label: Pulmonary Rehabilitation Group; Type: EXPERIMENTAL; Interventions: Behavioral: Pulmonary Intervention | Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Pulmonary Intervention; Assigned to Arm(s): Pulmonary Rehabilitation Group

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Noninvasive Ventilation Strategies for Early Treatment of RDS in Preterm Infants: An RCT
Brief Summary: The purpose of this study is to determine whether two different strategies of Non Invasive Ventilation (NIV) have different effect on length and failure of NIV support in preterm infants with respiratory distress syndrome (RDS).


Options:
A: Arm Label: NCPAP; Type: ACTIVE_COMPARATOR; Interventions: Device: nasal intermittent positive pressure ventilation | Arm Label: NIPPV; Type: EXPERIMENTAL; Interventions: Device: nasal intermittent positive pressure ventilation | Intervention Type: DEVICE; Name: nasal intermittent positive pressure ventilation; Assigned to Arm(s): NCPAP, NIPPV
B: Arm Label: CPAP ventilation mode; Type: ACTIVE_COMPARATOR; Interventions: Procedure: CPAP ventilation mode | Arm Label: NIPPV ventilation mode; Type: EXPERIMENTAL; Interventions: Procedure: NIPPV ventilation mode | Intervention Type: PROCEDURE; Name: CPAP ventilation mode; Assigned to Arm(s): CPAP ventilation mode | Intervention Type: PROCEDURE; Name: NIPPV ventilation mode; Assigned to Arm(s): NIPPV ventilation mode
C: Arm Label: NIMV- nasal respiratory support; Type: EXPERIMENTAL; Interventions: Device: NIMV with SLE ventilator vs HFNC via Vapotherm | Arm Label: HFNC- nasal respiratory support with HFNC; Type: EXPERIMENTAL; Interventions: Device: NIMV with SLE ventilator vs HFNC via Vapotherm | Intervention Type: DEVICE; Name: NIMV with SLE ventilator vs HFNC via Vapotherm; Assigned to Arm(s): HFNC- nasal respiratory support with HFNC, NIMV- nasal respiratory support
D: Arm Label: NSIPPV group; Type: ACTIVE_COMPARATOR; Interventions: Device: NSIPPV | Arm Label: BiPAP group; Type: ACTIVE_COMPARATOR; Interventions: Device: BiPAP | Intervention Type: DEVICE; Name: NSIPPV; Assigned to Arm(s): NSIPPV group | Intervention Type: DEVICE; Name: BiPAP; Assigned to Arm(s): BiPAP group

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Noninvasive Ventilation Strategies for Early Treatment of RDS in Preterm Infants: An RCT
Brief Summary: The purpose of this study is to determine whether two different strategies of Non Invasive Ventilation (NIV) have different effect on length and failure of NIV support in preterm infants with respiratory distress syndrome (RDS).


Options:
A: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Device: NIPPV | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Device: nCPAP | Intervention Type: DEVICE; Name: nCPAP; Assigned to Arm(s): B | Intervention Type: DEVICE; Name: NIPPV; Assigned to Arm(s): A
B: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Procedure: Biphasic Infant flow NCPAP | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Procedure: CPAP | Intervention Type: PROCEDURE; Name: Biphasic Infant flow NCPAP; Assigned to Arm(s): 1 | Intervention Type: PROCEDURE; Name: CPAP; Assigned to Arm(s): 2
C: Arm Label: NSIPPV group; Type: ACTIVE_COMPARATOR; Interventions: Device: NSIPPV | Arm Label: BiPAP group; Type: ACTIVE_COMPARATOR; Interventions: Device: BiPAP | Intervention Type: DEVICE; Name: NSIPPV; Assigned to Arm(s): NSIPPV group | Intervention Type: DEVICE; Name: BiPAP; Assigned to Arm(s): BiPAP group
D: Arm Label: NCPAP; Type: ACTIVE_COMPARATOR; Interventions: Device: nasal intermittent positive pressure ventilation | Arm Label: NIPPV; Type: EXPERIMENTAL; Interventions: Device: nasal intermittent positive pressure ventilation | Intervention Type: DEVICE; Name: nasal intermittent positive pressure ventilation; Assigned to Arm(s): NCPAP, NIPPV

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized, Double-Blind, Placebo-Controlled Study to Demonstrate the Efficacy and Long-Term Safety of Dupilumab in Adult Patients With Moderate-to-Severe Atopic Dermatitis
Brief Summary: The primary objective of the study was to demonstrate the efficacy of Dupilumab administered concomitantly with topical corticosteroid (TCS) through Week 16 in adult participants with moderate-to-severe atopic dermatitis (AD) compared to placebo administered concomitantly with TCS.


Options:
A: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: Dupilumab 300 mg; Type: EXPERIMENTAL; Interventions: Drug: Dupilumab | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo | Intervention Type: DRUG; Name: Dupilumab; Assigned to Arm(s): Dupilumab 300 mg
B: Arm Label: Placebo qw; Type: EXPERIMENTAL; Interventions: Drug: Placebo (for Dupilumab), Other: Topical Corticosteroid (TCS) | Arm Label: Dupilumab 300 mg q2w; Type: EXPERIMENTAL; Interventions: Drug: Dupilumab, Drug: Placebo (for Dupilumab), Other: Topical Corticosteroid (TCS) | Arm Label: Dupilumab 300 mg qw; Type: EXPERIMENTAL; Interventions: Drug: Dupilumab, Other: Topical Corticosteroid (TCS) | Intervention Type: DRUG; Name: Dupilumab; Assigned to Arm(s): Dupilumab 300 mg q2w, Dupilumab 300 mg qw | Intervention Type: DRUG; Name: Placebo (for Dupilumab); Assigned to Arm(s): Dupilumab 300 mg q2w, Placebo qw | Intervention Type: OTHER; Name: Topical Corticosteroid (TCS); Assigned to Arm(s): Dupilumab 300 mg q2w, Dupilumab 300 mg qw, Placebo qw
C: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Drug: Prednisolone | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Drug: Ciclosporine A | Intervention Type: DRUG; Name: Prednisolone; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: Ciclosporine A; Assigned to Arm(s): 2
D: Arm Label: 20 mg BID; Type: EXPERIMENTAL; Interventions: Drug: Apremilast | Arm Label: 30 mg BID; Type: EXPERIMENTAL; Interventions: Drug: Apremilast | Intervention Type: DRUG; Name: Apremilast; Assigned to Arm(s): 20 mg BID, 30 mg BID

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Effect of n-3 Fatty Acid Supplementation on the Expression of Sirt-1, Adiponectin Receptor 1 (AdipoR1) & Adiponectin Receptor 2 (AdipoR2) Genes of PBMC and Circulatory Levels of Resistin,Monocyte Chemotactic Protein (MCP-1) and Adiponectin of type2 Diabetes Patient
Brief Summary: The aim of this study is to determine the effects of supplementation with n-3 fatty acid or placebo for 10 weeks on the expression of Sirt-1, AdipoR1 \& AdipoR2 genes in the peripheral blood mononuclear cell (PBMC) and circulatory levels of Resistin, MCP-1 and Adiponectin of type2 diabetes patient


Options:
A: Arm Label: Soybean oil soft gels; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Soybean oil soft gels | Arm Label: Fish oil omega-3 EPA-rich soft gels; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Fish oil omega-3 EPA-rich soft gels | Intervention Type: DIETARY_SUPPLEMENT; Name: Soybean oil soft gels; Assigned to Arm(s): Soybean oil soft gels | Intervention Type: DIETARY_SUPPLEMENT; Name: Fish oil omega-3 EPA-rich soft gels; Assigned to Arm(s): Fish oil omega-3 EPA-rich soft gels
B: Arm Label: n-3 Fatty Acid Supplemetation; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: n-3 Fatty Acid | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Placebo | Intervention Type: DIETARY_SUPPLEMENT; Name: n-3 Fatty Acid; Assigned to Arm(s): n-3 Fatty Acid Supplemetation | Intervention Type: DIETARY_SUPPLEMENT; Name: Placebo; Assigned to Arm(s): Placebo
C: Arm Label: Infliximab; Type: EXPERIMENTAL; Interventions: Drug: Infliximab | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Infliximab; Assigned to Arm(s): Infliximab | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Omega-3 fatty acids | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Omega-3 fatty acids | Intervention Type: DIETARY_SUPPLEMENT; Name: Omega-3 fatty acids; Assigned to Arm(s): 1, 2

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effects of Clinical Music Improvisation on Resiliency in Adults Undergoing Infusion Therapy
Brief Summary: This study will investigate the impact of music therapy on newly diagnosed patients with cancer undergoing chemotherapy. Measurements used at baseline, middle and end of first cycle will be the Resiliency Scale (Wagnild and Young 1993); The HADS scale (hospital anxiety depression scale, Zigmond and Snaith 1983 )and and The CAS scale for pain (Color Analysis Scale).


Options:
A: Arm Label: Clinical Improvisation Instrumental Music Therapy; Type: EXPERIMENTAL; Interventions: Other: Clinical Improvisation Instrumental Music Therapy | Arm Label: Clinical Vocal Improvisation; Type: EXPERIMENTAL; Interventions: Other: Clinical Vocal Improvisation | Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Clinical Improvisation Instrumental Music Therapy; Assigned to Arm(s): Clinical Improvisation Instrumental Music Therapy | Intervention Type: OTHER; Name: Clinical Vocal Improvisation; Assigned to Arm(s): Clinical Vocal Improvisation
B: Arm Label: e-Psychotherapy; Type: EXPERIMENTAL; Interventions: Behavioral: e-CBT | Arm Label: Treatment as Usual; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: e-CBT; Assigned to Arm(s): e-Psychotherapy
C: Arm Label: Intervention - CBT; Type: EXPERIMENTAL; Interventions: Behavioral: Brief Cognitive Behavioral Therapy | Arm Label: Routine Care Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Brief Cognitive Behavioral Therapy; Assigned to Arm(s): Intervention - CBT
D: Arm Label: Music Group; Type: EXPERIMENTAL; Interventions: Behavioral: Guided Imagery and Music | Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Guided Imagery and Music; Assigned to Arm(s): Music Group

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effects of Clinical Music Improvisation on Resiliency in Adults Undergoing Infusion Therapy
Brief Summary: This study will investigate the impact of music therapy on newly diagnosed patients with cancer undergoing chemotherapy. Measurements used at baseline, middle and end of first cycle will be the Resiliency Scale (Wagnild and Young 1993); The HADS scale (hospital anxiety depression scale, Zigmond and Snaith 1983 )and and The CAS scale for pain (Color Analysis Scale).


Options:
A: Arm Label: Experimental Group; Type: EXPERIMENTAL; Interventions: Other: Music Intervention | Arm Label: Waitlist Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Music Intervention; Assigned to Arm(s): Experimental Group
B: Arm Label: Clinical Improvisation Instrumental Music Therapy; Type: EXPERIMENTAL; Interventions: Other: Clinical Improvisation Instrumental Music Therapy | Arm Label: Clinical Vocal Improvisation; Type: EXPERIMENTAL; Interventions: Other: Clinical Vocal Improvisation | Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Clinical Improvisation Instrumental Music Therapy; Assigned to Arm(s): Clinical Improvisation Instrumental Music Therapy | Intervention Type: OTHER; Name: Clinical Vocal Improvisation; Assigned to Arm(s): Clinical Vocal Improvisation
C: Arm Label: Control; Type: OTHER; Interventions: Behavioral: Sleep hygiene advice | Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Sleep hygiene advice, Behavioral: Bedtime music listening | Intervention Type: BEHAVIORAL; Name: Sleep hygiene advice; Assigned to Arm(s): Control, Intervention | Intervention Type: BEHAVIORAL; Name: Bedtime music listening; Assigned to Arm(s): Intervention
D: Arm Label: Experimental: Tailored Music; Type: EXPERIMENTAL; Interventions: Behavioral: Tailored music listening intervention | Arm Label: 4-week Wait-list control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Tailored music listening intervention; Assigned to Arm(s): Experimental: Tailored Music

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Integrative Medicine Group Visits: A Patient-Centered Approach to Reducing Chronic Pain and Depression in a Disparate Urban Population
Brief Summary: The purpose of this study is to determine whether Integrative Medicine Group Visits (IMGV) are effective for treating patients with chronic pain and depression.


Options:
A: Arm Label: Integrative Medicine Group Visits; Type: EXPERIMENTAL; Interventions: Behavioral: Integrative Medicine Group Visits | Arm Label: Standard of Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Integrative Medicine Group Visits; Assigned to Arm(s): Integrative Medicine Group Visits
B: Arm Label: CBT plus relaxation response; Type: EXPERIMENTAL; Interventions: Behavioral: Relaxation response and cognitive behavioral therapy | Arm Label: Relaxation Response; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Relaxation response | Arm Label: Education; Type: PLACEBO_COMPARATOR; Interventions: Other: RA education | Intervention Type: BEHAVIORAL; Name: Relaxation response and cognitive behavioral therapy; Assigned to Arm(s): CBT plus relaxation response | Intervention Type: BEHAVIORAL; Name: Relaxation response; Assigned to Arm(s): Relaxation Response | Intervention Type: OTHER; Name: RA education; Assigned to Arm(s): Education
C: Intervention Type: BEHAVIORAL; Name: cognitive-behavioral therapy; Assigned to Arm(s): N/A
D: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Psychoeducative program in fibromyalgic patients | Intervention Type: BEHAVIORAL; Name: Psychoeducative program in fibromyalgic patients; Assigned to Arm(s): 1

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized, Multi-center, Open-label, Phase 3 Study of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib in Combination With Obinutuzumab Versus Chlorambucil in Combination With Obinutuzumab in Subjects With Treatment-naïve Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Brief Summary: The primary objective of this study is to evaluate the efficacy of ibrutinib in combination with obinutuzumab compared to chlorambucil in combination with obinutuzumab based on the Independent Review Committee (IRC) assessment of progression free survival (PFS). Efficacy will be evaluated according to 2008 International Workshop for Chronic Lymphocytic Leukemia (IWCLL) criteria with the modification for treatment-related lymphocytosis, in subjects with treatment-naive CLL or SLL.


Options:
A: Arm Label: IBR + OB; Type: EXPERIMENTAL; Interventions: Drug: Ibrutinib, Drug: Obinutuzumab | Arm Label: CLB + OB; Type: EXPERIMENTAL; Interventions: Drug: Obinutuzumab, Drug: Chlorambucil | Intervention Type: DRUG; Name: Ibrutinib; Assigned to Arm(s): IBR + OB | Intervention Type: DRUG; Name: Obinutuzumab; Assigned to Arm(s): CLB + OB, IBR + OB | Intervention Type: DRUG; Name: Chlorambucil; Assigned to Arm(s): CLB + OB
B: Arm Label: Idelalisib + rituximab; Type: ACTIVE_COMPARATOR; Interventions: Drug: Idelalisib, Drug: Rituximab | Arm Label: Placebo + rituximab; Type: PLACEBO_COMPARATOR; Interventions: Drug: Rituximab, Drug: Placebo to match idelalisib | Intervention Type: DRUG; Name: Idelalisib; Assigned to Arm(s): Idelalisib + rituximab | Intervention Type: DRUG; Name: Rituximab; Assigned to Arm(s): Idelalisib + rituximab, Placebo + rituximab | Intervention Type: DRUG; Name: Placebo to match idelalisib; Assigned to Arm(s): Placebo + rituximab
C: Arm Label: Lenalidomide; Type: EXPERIMENTAL; Interventions: Drug: Lenalidomide | Intervention Type: DRUG; Name: Lenalidomide; Assigned to Arm(s): Lenalidomide
D: Arm Label: Bendamustine, rituximab, lenalidomide; Type: EXPERIMENTAL; Interventions: Drug: Bendamustine, Drug: Rituximab, Drug: Lenalidomide | Intervention Type: DRUG; Name: Bendamustine; Assigned to Arm(s): Bendamustine, rituximab, lenalidomide | Intervention Type: DRUG; Name: Rituximab; Assigned to Arm(s): Bendamustine, rituximab, lenalidomide | Intervention Type: DRUG; Name: Lenalidomide; Assigned to Arm(s): Bendamustine, rituximab, lenalidomide

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Reducing Symptoms of Depression and Anxiety in Adolescents With Inflammatory Bowel Disease in Order to Improve Quality of Life and the Clinical Course of Disease.
Brief Summary: The presented study aims to reduce symptoms of depression and anxiety in adolescents with inflammatory bowel disease and increased symptoms of anxiety and depression by using the disease specific CBT program (PASCET-PI)in order to improve quality of life and to improve the clinical course of disease.


Options:
A: Arm Label: Care as usual; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Cognitive Behavioral Therapy; Type: EXPERIMENTAL; Interventions: Behavioral: Cognitive behavioral therapy | Intervention Type: BEHAVIORAL; Name: Cognitive behavioral therapy; Assigned to Arm(s): Cognitive Behavioral Therapy
B: Intervention Type: DRUG; Name: citalopram; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: BuproprionSR; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: buspirone; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Lithium; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: mirtazapine; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: nortriptyline; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: sertraline; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: tranylcypromine; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: VenlafaxineXR; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: Cognitive Therapy; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: T3 (Triiodothyronine); Assigned to Arm(s): N/A
C: Arm Label: Cognitive Behavioral Therapy; Type: EXPERIMENTAL; Interventions: Behavioral: Cognitive Behavioral Therapy | Arm Label: Standard of Community Care Treatment; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Standard of Community Care Treatment | Intervention Type: BEHAVIORAL; Name: Cognitive Behavioral Therapy; Assigned to Arm(s): Cognitive Behavioral Therapy | Intervention Type: BEHAVIORAL; Name: Standard of Community Care Treatment; Assigned to Arm(s): Standard of Community Care Treatment
D: Arm Label: Clinic; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: BFST | Arm Label: Skype; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: BFST | Intervention Type: BEHAVIORAL; Name: BFST; Assigned to Arm(s): Clinic, Skype

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Higher Response of Vascular Endothelial Growth Factor and Angiotensin-II to Human Chorionic Gonadotropin in Women With Polycystic Ovary Syndrome
Brief Summary: This research is to investigate the response of vascular active factors, vascular endothelial growth factor (VEGF) and angiotensin-Ⅱ (AT-Ⅱ) to ovary stimulation during 24h in patients with polycystic ovary syndrome (PCOS).Controled prospective clinical study involved 60 women undergoing in vitro fertilization. Fifty-two patients with PCOS and 8 control cases were stimulated with human chorionic gonadotropin (HCG) during the early follicular phase of the menstrual cycle (4st to 7th days of the cycle).The blood was sampled before the injection (0 hour) and at the 3, 6, 12, 18 and 24 hours points after the stimulation. VEGF, AT-Ⅱ were measured by radioimmunoassay.


Options:
A: Arm Label: Letrozole -Berberine; Type: EXPERIMENTAL; Interventions: Drug: Letrozole -Berberine | Arm Label: Letrozole; Type: ACTIVE_COMPARATOR; Interventions: Drug: Letrozole | Arm Label: Berberine; Type: ACTIVE_COMPARATOR; Interventions: Drug: Berberine | Intervention Type: DRUG; Name: Letrozole -Berberine; Assigned to Arm(s): Letrozole -Berberine | Intervention Type: DRUG; Name: Letrozole; Assigned to Arm(s): Letrozole | Intervention Type: DRUG; Name: Berberine; Assigned to Arm(s): Berberine
B: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Drug: Clomiphene citrate | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Drug: Letrozole | Intervention Type: DRUG; Name: Clomiphene citrate; Assigned to Arm(s): A | Intervention Type: DRUG; Name: Letrozole; Assigned to Arm(s): B
C: Arm Label: Crispbread; Type: EXPERIMENTAL; Interventions: Behavioral: Crispbread | Arm Label: Liquid meal replacement; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Crispbread | Intervention Type: BEHAVIORAL; Name: Crispbread; Assigned to Arm(s): Crispbread, Liquid meal replacement
D: Arm Label: Group 1; Type: EXPERIMENTAL; Interventions: Drug: HCG | Arm Label: Group 2; Type: EXPERIMENTAL; Interventions: Drug: HCG | Arm Label: Group 3; Type: EXPERIMENTAL; Interventions: Drug: HCG | Arm Label: Group 4; Type: EXPERIMENTAL; Interventions: Drug: HCG | Intervention Type: DRUG; Name: HCG; Assigned to Arm(s): Group 1, Group 2, Group 3, Group 4

Answer: D