TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Computer-Assisted Guidance for Tobacco Dependence Interventions in Dental Offices
Brief Summary: Electronic dental records (EDR) are a potentially powerful tool to incorporate current scientific evidence into clinical practice by providing key information at the point of patient care. The investigators know that disseminating evidence-based guidelines is not sufficient to change clinical practice so innovative approaches need to be tested in dentistry. The composite expertise of the investigators and consultants on this project and a large group practice with multiple clinics utilizing one EDR are essential to address the aims of this study. This project will examine whether dentists and hygienists will assess interest in quitting and deliver a tobacco intervention more frequently when provided with computer assisted guidance compared to a control group. Specifically the investigators will measure the delivery of questions assessing willingness to change and appropriate interventions based on willingness to change by measuring the recording of these activities in the EDR and patient receipt of these recommendations through a phone survey. In addition, the study will do a qualitative assessment of the patient perceived value of the provider-patient encounter to further inform us about patient perception of this interaction. The investigators want to know if dental providers will utilize these tools during the dental encounter. If they are used, the investigators would propose further studies examining smoking cessation rates. The investigators were not able to measure cessation rates due to the short two year timeline of this funding mechanism. This tool has potential application for other clinical topics, which makes this approach very innovative when considering the translation of evidence into the unique clinical practice of dentistry.


Options:
A: Arm Label: Control (Usual care); Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Tobacco Cessation Tool (CATI Tool); Type: EXPERIMENTAL; Interventions: Behavioral: CATI Tool | Intervention Type: BEHAVIORAL; Name: CATI Tool; Assigned to Arm(s): Tobacco Cessation Tool (CATI Tool)
B: Arm Label: Implementation of intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Training in smoking cessation counseling | Arm Label: No implementation of the intervention; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Training in smoking cessation counseling; Assigned to Arm(s): Implementation of intervention
C: Intervention Type: BEHAVIORAL; Name: QuitLink (office support system for quit line referral); Assigned to Arm(s): N/A
D: Intervention Type: BEHAVIORAL; Name: Advice; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: Motivational Interviewing; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Nicotine Gum and Patch; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Bupropion; Assigned to Arm(s): N/A

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effects on the Septic Patient's Microcirculation of the Transfusion of Three Different Types of Concentrated Red Blood Cells.
Brief Summary: Aim of the study is to evaluate the effects, on microcirculation of septic patient, of three types of RBCs: 1- fresh standard RBCs (storage \<10 days); 2-leukodepleted RBCs and 3-old standard RBCs (storage \>15 days) respectively. Before and 1 hour after the transfusion, microcirculation is evaluated using Sidestream Dark Field Imaging (SDF) and Near InfraRed Spectroscopy (NIRS) with vascular occlusion test. We also monitor temperature, heart rate, mean blood pressure, hemochrome, blood gases, blood lactates and SOFA score.


Options:
A: Arm Label: Biological; Type: EXPERIMENTAL; Interventions: Biological: Transfusion | Arm Label: Standard PRBCs; Type: EXPERIMENTAL; Interventions: Biological: Transfusion | Intervention Type: BIOLOGICAL; Name: Transfusion; Assigned to Arm(s): Biological, Standard PRBCs
B: Arm Label: Fresh not-leukocyte-reduced RBCs; Type: ACTIVE_COMPARATOR; Interventions: Biological: Blood transfusion | Arm Label: Fresh RBCs leukocyte-reduced; Type: ACTIVE_COMPARATOR; Interventions: Biological: Blood transfusion | Arm Label: RBCs with storage longer than 15 days; Type: ACTIVE_COMPARATOR; Interventions: Biological: Blood transfusion | Intervention Type: BIOLOGICAL; Name: Blood transfusion; Assigned to Arm(s): Fresh RBCs leukocyte-reduced, Fresh not-leukocyte-reduced RBCs, RBCs with storage longer than 15 days
C: Arm Label: Shorter-storage red blood cell units; Type: ACTIVE_COMPARATOR; Interventions: Biological: Red blood cell units stored <= 10 days | Arm Label: Longer-storage red blood cell units; Type: ACTIVE_COMPARATOR; Interventions: Biological: Red blood cell units stored >= 21 days | Intervention Type: BIOLOGICAL; Name: Red blood cell units stored <= 10 days; Assigned to Arm(s): Shorter-storage red blood cell units | Intervention Type: BIOLOGICAL; Name: Red blood cell units stored >= 21 days; Assigned to Arm(s): Longer-storage red blood cell units
D: Arm Label: Prolonged RBC storage; Type: ACTIVE_COMPARATOR; Interventions: Biological: Prolonged RBC storage | Arm Label: Short RBC storage; Type: ACTIVE_COMPARATOR; Interventions: Biological: Short RBC storage | Intervention Type: BIOLOGICAL; Name: Prolonged RBC storage; Assigned to Arm(s): Prolonged RBC storage | Intervention Type: BIOLOGICAL; Name: Short RBC storage; Assigned to Arm(s): Short RBC storage

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Preventing Obesity in the Worksite: A Multi-Message, Multi-"Step" Approach
Brief Summary: The purpose of this research study is to develop, implement, and evaluate a multi-component obesity prevention program in a workplace setting. A quasi-experimental design will be utilized, with hospital employees receiving the intervention and clinic employees serving as the comparison group. It is hypothesized that the intervention group will see greater changes in healthier eating, increased participation in physical activity, and reduced risk for obesity (weight, BMI, waist circumference).


Options:
A: Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Intervention | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Intervention; Assigned to Arm(s): Intervention
B: Arm Label: Directive; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Directive smoking cessation coaching | Arm Label: Nondirective; Type: EXPERIMENTAL; Interventions: Behavioral: Nondirective smoking cessation coaching | Intervention Type: BEHAVIORAL; Name: Nondirective smoking cessation coaching; Assigned to Arm(s): Nondirective | Intervention Type: BEHAVIORAL; Name: Directive smoking cessation coaching; Assigned to Arm(s): Directive
C: Intervention Type: BEHAVIORAL; Name: Financial incentives; Assigned to Arm(s): N/A
D: Arm Label: weight gain prevention intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Weight Gain Prevention Intervention | Arm Label: No treatment comparison group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Weight Gain Prevention Intervention; Assigned to Arm(s): weight gain prevention intervention

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Preventing Cholestasis in Premature Infants Using SMOFLipid®
Brief Summary: Preterm infants of extreme low birth weight (ELBW, \< 1000 gram birth weight) cannot immediately be nourished with mother´s or formula milk and are typically dependent on parenteral nutrition (PN) for a prolonged period of time. This puts them at risk for liver complications of PN, namely parenteral nutrition associated cholestasis (PNAC).

Intravenous lipid emulsions (ILE) based on soy bean oil are standard of care for provision of energy and essential fatty acids in preterm infants. However, they might be implicated in the pathogenesis of PNAC.

ILEs based on pure fish oil are proposed for therapy of PNAC. Recently a lipid emulsion containing 15 % fish oil together with soy bean, olive and MCT oil has become available in Europe (SMOFLIPID®). Such a balanced lipid emulsion might be more favourable than the standard soy bean oil emulsion (Intralipid®) concerning the development of PNAC. Furthermore ILEs containing fish oil might exert a positive effect on neurodevelopment. However, there are no data so far.

The study aims to evaluate the fish oil containing ILE "SMOFlipid®" for its protective effect against PNAC in ELBW infants compared to standard treatment with the soy bean based ILE "Intralipid®". Furthermore neurodevelopment at 12 and 24 months of corrected gestational age will be investigated.


Options:
A: Arm Label: Smoflipid; Type: EXPERIMENTAL; Interventions: Drug: SMOFLIPID | Arm Label: Intralipid; Type: ACTIVE_COMPARATOR; Interventions: Drug: INTRALIPID | Intervention Type: DRUG; Name: SMOFLIPID; Assigned to Arm(s): Smoflipid | Intervention Type: DRUG; Name: INTRALIPID; Assigned to Arm(s): Intralipid
B: Arm Label: 1) Intralipid; Type: ACTIVE_COMPARATOR; Interventions: Drug: Intralipid 20% | Arm Label: 2) SMOFlipid; Type: EXPERIMENTAL; Interventions: Drug: SMOFlipid 20% | Intervention Type: DRUG; Name: Intralipid 20%; Assigned to Arm(s): 1) Intralipid | Intervention Type: DRUG; Name: SMOFlipid 20%; Assigned to Arm(s): 2) SMOFlipid
C: Arm Label: SMOFlipid; Type: EXPERIMENTAL; Interventions: Other: SMOFlipid | Arm Label: Lipofundin; Type: OTHER; Interventions: Other: Lipofundin | Intervention Type: OTHER; Name: SMOFlipid; Assigned to Arm(s): SMOFlipid | Intervention Type: OTHER; Name: Lipofundin; Assigned to Arm(s): Lipofundin
D: Arm Label: Olive oil lipid emulsion; Type: EXPERIMENTAL; Interventions: Drug: ClinOleic | Arm Label: MCT/LCT lipid emulsion; Type: EXPERIMENTAL; Interventions: Drug: Lipofundin | Arm Label: LCT lipid emulsion; Type: EXPERIMENTAL; Interventions: Drug: Intralipid | Intervention Type: DRUG; Name: ClinOleic; Assigned to Arm(s): Olive oil lipid emulsion | Intervention Type: DRUG; Name: Lipofundin; Assigned to Arm(s): MCT/LCT lipid emulsion | Intervention Type: DRUG; Name: Intralipid; Assigned to Arm(s): LCT lipid emulsion

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Pharmacovigilance Study on the Safety of Integrated Treatment of Trachoma and Lymphatic Filariasis in Children and Adults Living in the Sikasso Region of Mali
Brief Summary: The purpose of this study is to determine whether the triple co administration of albendazole, ivermectin and azithromycine is as safe as the current treatment scheme that consists to treat with albendazole plus ivermectin together and a week later to treat with azithromycin in areas co endemic for lymphatic filariasis and trachoma.


Options:
A: Arm Label: Biannual mass oral azithromycin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Azithromycin | Arm Label: Biannual mass oral placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Azithromycin; Assigned to Arm(s): Biannual mass oral azithromycin | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Biannual mass oral placebo
B: Intervention Type: DRUG; Name: Mass treatment with oral azithromycin to an entire village; Assigned to Arm(s): N/A
C: Intervention Type: DRUG; Name: triple co administration at once of the combination of Albendazole + ivermectin + azithromycin; Assigned to Arm(s): N/A
D: Arm Label: J; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: K; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: L; Type: OTHER; Interventions: Drug: mass treatment with oral azithromycin | Arm Label: M; Type: OTHER; Interventions: Drug: mass treatment with oral azithromycin | Arm Label: N; Type: EXPERIMENTAL; Interventions: Drug: mass treatment with oral azithromycin | Arm Label: O; Type: EXPERIMENTAL; Interventions: Drug: mass treatment with oral azithromycin | Intervention Type: DRUG; Name: mass treatment with oral azithromycin; Assigned to Arm(s): L, M, N, O

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Intensified Secondary Prevention Intending a Reduction of Recurrent Events in TIA and Minor Stroke Patients (INSPiRE-TMS) A Randomized Trial Comparing a Patient Centered Support Program Versus Conventional Car
Brief Summary: Patients after TIA or Stroke are at high risk of experiencing a new stroke or myocardial infarction. Poor adherence to evidence based secondary prevention regimens is frequently seen. Support programs for patients may not only improve adherence to recommended therapies but also reduce the recurrence rate of stroke and heart attack. The investigators hypothesize that compared to regular care, a structured and patient centered secondary prevention program will lead to a relative risk reduction of at least 28% of recurrent vascular events.


Options:
A: Arm Label: SystemCHANGE Group Lifestyle counseling; Type: EXPERIMENTAL; Interventions: Behavioral: SystemCHANGE Group Lifestyle counseling | Arm Label: Phone Lifestyle Counseling; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Phone Lifestyle Counseling | Intervention Type: BEHAVIORAL; Name: SystemCHANGE Group Lifestyle counseling; Assigned to Arm(s): SystemCHANGE Group Lifestyle counseling | Intervention Type: BEHAVIORAL; Name: Phone Lifestyle Counseling; Assigned to Arm(s): Phone Lifestyle Counseling
B: Intervention Type: DRUG; Name: Optimal treatment; Assigned to Arm(s): N/A
C: Arm Label: Regular care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Support program; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Patient centered structured support program | Intervention Type: BEHAVIORAL; Name: Patient centered structured support program; Assigned to Arm(s): Support program
D: Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Intervention - a validated home BP monitor and support from the specialist nurse | Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Control - usual care (BP monitoring by their practice) | Intervention Type: BEHAVIORAL; Name: Intervention - a validated home BP monitor and support from the specialist nurse; Assigned to Arm(s): Intervention | Intervention Type: BEHAVIORAL; Name: Control - usual care (BP monitoring by their practice); Assigned to Arm(s): Control

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Intensified Secondary Prevention Intending a Reduction of Recurrent Events in TIA and Minor Stroke Patients (INSPiRE-TMS) A Randomized Trial Comparing a Patient Centered Support Program Versus Conventional Car
Brief Summary: Patients after TIA or Stroke are at high risk of experiencing a new stroke or myocardial infarction. Poor adherence to evidence based secondary prevention regimens is frequently seen. Support programs for patients may not only improve adherence to recommended therapies but also reduce the recurrence rate of stroke and heart attack. The investigators hypothesize that compared to regular care, a structured and patient centered secondary prevention program will lead to a relative risk reduction of at least 28% of recurrent vascular events.


Options:
A: Arm Label: Peer-Led Stroke Recurrence Prevention Education; Type: EXPERIMENTAL; Interventions: Behavioral: Prevent Return of Stroke | Arm Label: Usual Care (Delayed Intervention); Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Prevent Return of Stroke | Intervention Type: BEHAVIORAL; Name: Prevent Return of Stroke; Assigned to Arm(s): Peer-Led Stroke Recurrence Prevention Education | Intervention Type: BEHAVIORAL; Name: Prevent Return of Stroke; Assigned to Arm(s): Usual Care (Delayed Intervention)
B: Arm Label: PREVENT program; Type: EXPERIMENTAL; Interventions: Behavioral: PREVENT program | Arm Label: Usual Care; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Usual Care | Intervention Type: BEHAVIORAL; Name: PREVENT program; Assigned to Arm(s): PREVENT program | Intervention Type: BEHAVIORAL; Name: Usual Care; Assigned to Arm(s): Usual Care
C: Arm Label: Regular care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Support program; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Patient centered structured support program | Intervention Type: BEHAVIORAL; Name: Patient centered structured support program; Assigned to Arm(s): Support program
D: Arm Label: Intervention for diet, exercise; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Educational intervention for diet and physical activity | Arm Label: Control; Type: OTHER; Interventions: Behavioral: Educational message on skin cancer awareness | Intervention Type: BEHAVIORAL; Name: Educational intervention for diet and physical activity; Assigned to Arm(s): Intervention for diet, exercise | Intervention Type: BEHAVIORAL; Name: Educational message on skin cancer awareness; Assigned to Arm(s): Control

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Surgical Replacement and Transcatheter Aortic Valve Implantation (SURTAVI)
Brief Summary: The purpose of the study is to investigate the safety and efficacy of transcatheter aortic valve implantation (TAVI) in patients with severe, symptomatic Aortic Stenosis (AS) at intermediate surgical risk by randomizing patients to either Surgical Aortic Valve Replacement (SAVR) or TAVI with the Medtronic CoreValve® System.

Single Arm: The purpose of this trial is to evaluate the safety and effectiveness of transcatheter aortic valve implementation (TAVI) in patients with severe symptomatic Aortic Stenosis (AS) at intermediate surgical risk with TAVI. This is a non-randomized phase of the pivotal clinical trial.


Options:
A: Arm Label: A; Type: EXPERIMENTAL; Interventions: Procedure: CA-TAVR, Device: Amplatzer Duct Occluder | Intervention Type: PROCEDURE; Name: CA-TAVR; Assigned to Arm(s): A | Intervention Type: DEVICE; Name: Amplatzer Duct Occluder; Assigned to Arm(s): A
B: Arm Label: Surgical aortic valve replacement (SAVR); Type: ACTIVE_COMPARATOR; Interventions: Procedure: SAVR | Arm Label: Transcatheter aortic valve replacement (TAVR); Type: EXPERIMENTAL; Interventions: Device: SAPIEN 3 THV | Intervention Type: PROCEDURE; Name: SAVR; Assigned to Arm(s): Surgical aortic valve replacement (SAVR) | Intervention Type: DEVICE; Name: SAPIEN 3 THV; Assigned to Arm(s): Transcatheter aortic valve replacement (TAVR)
C: Arm Label: Medtronic CoreValve® System TAVI; Type: EXPERIMENTAL; Interventions: Device: Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI), Device: Medtronic CoreValve® Evolut R System Transcatheter Aortic Valve Implantation (TAVI) | Arm Label: SAVR; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Surgical Aortic Valve Replacement (SAVR) | Intervention Type: DEVICE; Name: Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI); Assigned to Arm(s): Medtronic CoreValve® System TAVI | Intervention Type: PROCEDURE; Name: Surgical Aortic Valve Replacement (SAVR); Assigned to Arm(s): SAVR | Intervention Type: DEVICE; Name: Medtronic CoreValve® Evolut R System Transcatheter Aortic Valve Implantation (TAVI); Assigned to Arm(s): Medtronic CoreValve® System TAVI
D: Arm Label: PIIA - SAPIEN XT; Type: EXPERIMENTAL; Interventions: Device: TAVR Implantation with SAPIEN XT | Arm Label: Control: SAVR; Type: ACTIVE_COMPARATOR; Interventions: Device: SAVR Implantation | Intervention Type: DEVICE; Name: TAVR Implantation with SAPIEN XT; Assigned to Arm(s): PIIA - SAPIEN XT | Intervention Type: DEVICE; Name: SAVR Implantation; Assigned to Arm(s): Control: SAVR

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Prospective Study of RBC Transfusion in Children With Severe Anemia
Brief Summary: The hypothesis of this study is that prolonged-storage RBCs are not inferior to short-storage RBCs for the time required to clear elevated blood lactate levels in children with severe anemia.


Options:
A: Arm Label: Short storage; Type: EXPERIMENTAL; Interventions: Biological: Blood transfusion | Arm Label: Long storage arm; Type: ACTIVE_COMPARATOR; Interventions: Biological: Blood transfusion | Intervention Type: BIOLOGICAL; Name: Blood transfusion; Assigned to Arm(s): Long storage arm, Short storage
B: Arm Label: Shorter-storage red blood cell units; Type: ACTIVE_COMPARATOR; Interventions: Biological: Red blood cell units stored <= 10 days | Arm Label: Longer-storage red blood cell units; Type: ACTIVE_COMPARATOR; Interventions: Biological: Red blood cell units stored >= 21 days | Intervention Type: BIOLOGICAL; Name: Red blood cell units stored <= 10 days; Assigned to Arm(s): Shorter-storage red blood cell units | Intervention Type: BIOLOGICAL; Name: Red blood cell units stored >= 21 days; Assigned to Arm(s): Longer-storage red blood cell units
C: Arm Label: Fresh transfusion; Type: OTHER; Interventions: Procedure: Fresh transfusion, Procedure: Old transfusion | Arm Label: Old transfusion; Type: EXPERIMENTAL; Interventions: Procedure: Fresh transfusion, Procedure: Old transfusion | Intervention Type: PROCEDURE; Name: Fresh transfusion; Assigned to Arm(s): Fresh transfusion, Old transfusion | Intervention Type: PROCEDURE; Name: Old transfusion; Assigned to Arm(s): Fresh transfusion, Old transfusion
D: Arm Label: Short-storage RBC; Type: ACTIVE_COMPARATOR; Interventions: Biological: RBC transfusion | Arm Label: Prolonged-storage RBC; Type: ACTIVE_COMPARATOR; Interventions: Biological: RBC transfusion | Intervention Type: BIOLOGICAL; Name: RBC transfusion; Assigned to Arm(s): Prolonged-storage RBC, Short-storage RBC

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Prospective Study of RBC Transfusion in Children With Severe Anemia
Brief Summary: The hypothesis of this study is that prolonged-storage RBCs are not inferior to short-storage RBCs for the time required to clear elevated blood lactate levels in children with severe anemia.


Options:
A: Arm Label: Short-storage RBC; Type: ACTIVE_COMPARATOR; Interventions: Biological: RBC transfusion | Arm Label: Prolonged-storage RBC; Type: ACTIVE_COMPARATOR; Interventions: Biological: RBC transfusion | Intervention Type: BIOLOGICAL; Name: RBC transfusion; Assigned to Arm(s): Prolonged-storage RBC, Short-storage RBC
B: Arm Label: Low transfusion threshold; Type: EXPERIMENTAL; Interventions: Biological: Red blood cell transfusion | Arm Label: High transfusion threshold; Type: ACTIVE_COMPARATOR; Interventions: Biological: Red blood cell transfusion | Intervention Type: BIOLOGICAL; Name: Red blood cell transfusion; Assigned to Arm(s): High transfusion threshold, Low transfusion threshold
C: Arm Label: Restrictive Red blood cell Transfusion; Type: EXPERIMENTAL; Interventions: Other: Red blood cell Transfusion | Arm Label: Liberal Red blood Cell Transfusion; Type: ACTIVE_COMPARATOR; Interventions: Other: Red blood cell Transfusion | Intervention Type: OTHER; Name: Red blood cell Transfusion; Assigned to Arm(s): Liberal Red blood Cell Transfusion, Restrictive Red blood cell Transfusion
D: Intervention Type: DRUG; Name: Red blood cell transfusion; Assigned to Arm(s): N/A

Answer: A