Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Evaluate Triple-Drug Therapy With Diethylcarbamize (DEC), Albendazole (ALB) and Ivermectin (IVM) That Could Accelerate LF Elimination Outside of Africa
Brief Summary: This study will determine if a combination of 3 drugs used to treat the infection that cause lymphatic filariasis (LF) due to Wuchereria bancrofti infection are more effective in killing or sterilizing the adult worms compared to just 2 of the 3 drugs that usually given to treat this infection. The three drugs used together are called albendazole (ALB), ivermectin (IVM) and diethylcarbamazine (DEC). The usual treatment in Papua New Guinea (PNG) for lymphatic filariasis are DEC and ALB. A combination of these 3 drugs has not been previously used to treat LF.


Options:
A: Arm Label: albendazole 400mg and ivermectin 200mcg/kg; Type: ACTIVE_COMPARATOR; Interventions: Drug: Albendazole 400mg and ivermectin 200mcg/kg | Arm Label: Albendazole 800mg and ivermectin 400mcg/kg; Type: ACTIVE_COMPARATOR; Interventions: Drug: Albendazole and ivermectin | Arm Label: Albendazole 400mg and ivermectin 200mcg/kg; Type: ACTIVE_COMPARATOR; Interventions: Drug: Albendazole 400mg and ivermectin 200mcg/kg | Arm Label: Albendazole 800mg and ivermectin 400mcg /kg bi-annually; Type: ACTIVE_COMPARATOR; Interventions: Drug: albendazole 800mg and ivermectin 400mcg/kg bi-annually | Intervention Type: DRUG; Name: Albendazole 400mg and ivermectin 200mcg/kg; Assigned to Arm(s): Albendazole 400mg and ivermectin 200mcg/kg, albendazole 400mg and ivermectin 200mcg/kg | Intervention Type: DRUG; Name: Albendazole and ivermectin; Assigned to Arm(s): Albendazole 800mg and ivermectin 400mcg/kg | Intervention Type: DRUG; Name: Albendazole 400mg and ivermectin 200mcg/kg; Assigned to Arm(s): Albendazole 400mg and ivermectin 200mcg/kg, albendazole 400mg and ivermectin 200mcg/kg | Intervention Type: DRUG; Name: albendazole 800mg and ivermectin 400mcg/kg bi-annually; Assigned to Arm(s): Albendazole 800mg and ivermectin 400mcg /kg bi-annually
B: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Drug: albendazole + ivermectin + praziquantel | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Drug: albendazole + ivermectin + (1 week later) praziquantel | Intervention Type: DRUG; Name: albendazole + ivermectin + praziquantel; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: albendazole + ivermectin + (1 week later) praziquantel; Assigned to Arm(s): 2
C: Arm Label: DEC + ALB sequential; Type: EXPERIMENTAL; Interventions: Drug: Diethylcarbamazine, Drug: Albendazole | Arm Label: DEC + ALB co-admin; Type: EXPERIMENTAL; Interventions: Drug: Diethylcarbamazine, Drug: Albendazole | Arm Label: DEC + DOXY co-admin; Type: EXPERIMENTAL; Interventions: Drug: Diethylcarbamazine, Drug: Doxycycline | Arm Label: Diethylcarbamazine (DEC); Type: ACTIVE_COMPARATOR; Interventions: Drug: Diethylcarbamazine | Intervention Type: DRUG; Name: Diethylcarbamazine; Assigned to Arm(s): DEC + ALB co-admin, DEC + ALB sequential, DEC + DOXY co-admin, Diethylcarbamazine (DEC) | Intervention Type: DRUG; Name: Albendazole; Assigned to Arm(s): DEC + ALB co-admin, DEC + ALB sequential | Intervention Type: DRUG; Name: Doxycycline; Assigned to Arm(s): DEC + DOXY co-admin
D: Arm Label: standard treatment; Type: ACTIVE_COMPARATOR; Interventions: Drug: Diethylcarbamazine, Drug: Albendazole | Arm Label: DEC 6 mg/kg + Alb 400 mg x 1; Type: EXPERIMENTAL; Interventions: Drug: Diethylcarbamazine, Drug: Albendazole | Arm Label: DEC + ALB + IVM; Type: EXPERIMENTAL; Interventions: Drug: Diethylcarbamazine, Drug: Albendazole, Drug: Ivermectin | Intervention Type: DRUG; Name: Diethylcarbamazine; Assigned to Arm(s): DEC + ALB + IVM, DEC 6 mg/kg + Alb 400 mg x 1, standard treatment | Intervention Type: DRUG; Name: Albendazole; Assigned to Arm(s): DEC + ALB + IVM, DEC 6 mg/kg + Alb 400 mg x 1, standard treatment | Intervention Type: DRUG; Name: Ivermectin; Assigned to Arm(s): DEC + ALB + IVM

Answer: D