Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Glycaemic Response to Oral Nutrition Support During Haemodialysis
Brief Summary: Patients with kidney, or renal, failure require life-saving treatment with regular dialysis. Dialysis is a form of treatment that simulates some kidney functions; to remove harmful waste products and extra water from the blood. Almost one-third of people with kidney failure also have diabetes, as diabetes is one of the leading causes of kidney disease in the United Kingdom, usually due to poor blood sugar control over a long period of time. Malnutrition is common in patients needing dialysis due to kidney failure causing fatigue, taste changes and a build up of waste products, which can reduce appetite. Treatment of malnutrition involves increasing both the energy and protein intake from food and drinks, and milk-drink style specialist nutrition drinks are often given to dialysis patients due to their specific dietary needs. These nutrition drinks can increase blood sugar levels and optimal control for diabetes may be difficult. This research study aims to measure the blood sugar response to a "slow-release" sugar nutrition drink specifically designed for dialysis patients, which may result in a lower blood sugar level, compared to standard nutrition drinks, consumed during a dialysis session. 28 patients with diabetes and having regular dialysis treatment will enrol in the study. Patients will be asked to drink 1 of 3 different nutrition drinks, once a week for 3 weeks during their regular dialysis treatment. Blood sugar levels will be measured from the blood samples taken from the patient's circulation directly before it enters the dialysis machine over 3 hours and the maximum blood sugar reading and total blood sugar response will be measured. Differences between the 3 drinks will be tested statistically. The results will help to advise patients with diabetes and kidney failure on the most suitable type of nutrition drink to consume during dialysis.


Options:
A: Arm Label: treated group; Type: EXPERIMENTAL; Interventions: Other: training on ergonomic bicycle, Drug: Testosterone, Drug: Oral nutritional supplementation, Drug: n3 polyunsaturated fatty acid | Arm Label: control group; Type: OTHER; Interventions: Drug: Oral nutritional supplementation | Intervention Type: OTHER; Name: training on ergonomic bicycle; Assigned to Arm(s): treated group | Intervention Type: DRUG; Name: Testosterone; Assigned to Arm(s): treated group | Intervention Type: DRUG; Name: Oral nutritional supplementation; Assigned to Arm(s): control group, treated group | Intervention Type: DRUG; Name: n3 polyunsaturated fatty acid; Assigned to Arm(s): treated group
B: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Pro-Stat | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Pro-Stat | Arm Label: 3; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: 4; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DIETARY_SUPPLEMENT; Name: Pro-Stat; Assigned to Arm(s): 1, 2
C: Arm Label: modified carbohydrate drink; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Nepro HP (Abbott Nutrition) | Arm Label: macronutrient matched drink; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Fortisip compact protein 125 ml + Calogen 20ml (Nutricia) | Arm Label: standard drink; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Fortisip compact 125 ml (Nutricia) | Intervention Type: DIETARY_SUPPLEMENT; Name: Nepro HP (Abbott Nutrition); Assigned to Arm(s): modified carbohydrate drink | Intervention Type: DIETARY_SUPPLEMENT; Name: Fortisip compact protein 125 ml + Calogen 20ml (Nutricia); Assigned to Arm(s): macronutrient matched drink | Intervention Type: DIETARY_SUPPLEMENT; Name: Fortisip compact 125 ml (Nutricia); Assigned to Arm(s): standard drink
D: Arm Label: Standard Hemodialysis; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Hemodialysis with Nutrition Supplement; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Nepro | Arm Label: Nutrition Supplement; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Nepro | Intervention Type: DIETARY_SUPPLEMENT; Name: Nepro; Assigned to Arm(s): Hemodialysis with Nutrition Supplement, Nutrition Supplement

Answer: C