Please select the eligibility criteria that correspond to the clinical trial below.
Title: Intensified Secondary Prevention Intending a Reduction of Recurrent Events in TIA and Minor Stroke Patients (INSPiRE-TMS) A Randomized Trial Comparing a Patient Centered Support Program Versus Conventional Car
Brief Summary: Patients after TIA or Stroke are at high risk of experiencing a new stroke or myocardial infarction. Poor adherence to evidence based secondary prevention regimens is frequently seen. Support programs for patients may not only improve adherence to recommended therapies but also reduce the recurrence rate of stroke and heart attack. The investigators hypothesize that compared to regular care, a structured and patient centered secondary prevention program will lead to a relative risk reduction of at least 28% of recurrent vascular events.


Options:
A: Inclusion Criteria Stroke:

* Physician-confirmed diagnosis of stroke (\> 6 weeks)
* Body mass index between 23 to 45 kg/m2
* Age 30 to 75 years

Exclusion Criteria Stroke:

* Pregnant or plans to become pregnant in the next 6 months
* Current participation in a face-to-face weight management program
* Uncontrolled diabetes (hospitalization within the prior 6 months)
* Serious mental illness
* Thyroid and adrenal gland diseases
* Inability to walk 3 meters with or without a cane or walker
* Severe cardiopulmonary disease that limits engagement in physical activity (e.g., myocardial infarction, congestive heart failure, coronary artery bypass grafting or valve replacement during the past three months, serious cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, and pulmonary embolus) or abnormal blood pressure or heart rate response after the 6-Minute Walking Test (e.g., a drop in systolic blood pressure of \>10mmHg from baseline)
* Severe cognitive deficits (Screening questioanire called the Short Orientation Memory-Concentration \< 12)
* Currently taking oral corticosteroids, antipsychotic (except for depression medication), or medications specifically for weight loss
* 3 or more falls in the past month
* Bulimia
* Unable to speak English over the phone
* Able to eat independently and is not on a special diet because of difficulty in swallowing
* Unstable weight (gained or lost \>10lbs in the last two months)

Inclusion Criteria MS or RA:

* Physician-confirmed diagnosis of multiple sclerosis or rheumatoid arthritis
* Body mass index between 23 to 45 kg/m2

Exclusion Criteria MS or RA:

* Pregnant or plans to become pregnant in the next 6 months
* Current participation in a face-to-face weight management program
* Uncontrolled diabetes (hospitalization within the prior 6 months)
* Serious mental illness
* Inability to walk 3 meters with or without a cane or walker
* Severe cardiopulmonary disease that limits engagement in physical activity
* Severe cognitive deficits (Short Orientation Memory-Concentration \< 12)
* Currently taking oral corticosteroids, antipsychotic (except for depression medication), or medications specifically for weight loss
* 3 or more falls in the past month
* Bulimia
* Unable to speak English
* Uncontrolled thyroid or adrenal disease (change in type and dosage of medication within the prior 3 months)
B: Inclusion Criteria:

Ischemic stroke Kaiser-Permanente Health Plan Member with Pharmacy Benefit Discharged alive to home

Exclusion Criteria:

tpA patients Hemorrhagic stroke TIA Significant comorbidities
C: Inclusion Criteria:

* Acute cerebrovascular event (either TIA or minor Stroke within 14 days before study inclusion) according to the following definitions:
* TIA (clinical restitution within 24 hours and ABCD2-Score ≥3) or visible DWI-lesion in MRI
* Minor stroke (mRankin ≤2 at time of inclusion)
* Patients with at least one of the following treatable risk factors:
* Arterial Hypertension
* Diabetes mellitus
* Atrial Fibrillation
* Smoking
* Written informed consent prior to study inclusion
* Realistic perspective in keeping the outpatient appointments

Exclusion Criteria:

* Distance from home to study center not in suitable range for keeping the outpatient appointments
* cognitive impairment jeopardizing adherence to the support program
* Modified Rankin Score \>2 at time of study inclusion
* Malignant disease with life expectancy of less than 3 years
* relevant alcohol or other substance abuse (except for nicotine)
* Stroke or TIA etiology without options for evidence based secondary prevention (e.g. dissection or vasculitis)
D: Inclusion Criteria:

* Stroke or TIA in last 9 months
* Blood pressure above 140/85 when measured more than 1 week after stroke or on anti hypertensive medication

Exclusion Criteria:

* Severe illness likely to dominate pattern of care
* Already using home blood pressure monitor
* Non-English speaking
* Severe cognitive impairment (AMTS\<7)
* Known secondary hypertension

Answer: C