Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Improving the Population-Wide Effectiveness of U.S. Tobacco Cessation Quitlines
Brief Summary: Research shows that smoking cessation is the most significant preventable health behavior change that a person can make to lower cancer risk. In addition, telephone quitlines are an effective, science-based smoking cessation treatment that is universally accessible to smokers in the U.S. However, little research has explored promising approaches that could increase quitline use, improve quit rates, and inform resource allocation for quitline services. The proposed study will test three promising enhancements to the standard quitline treatment that typically consists of counseling and, possibly 2 weeks of a NRT medication. These enhancements are: 1) combination nicotine replacement therapy as recommended by the United States Public Health Service Clinical Practice Guideline on Treating Tobacco Use and Dependence; 2) extended duration of cessation medication use; and 3) an innovative counseling addition - cognitive medication adherence counseling - to optimize adherence to cessation medication. In addition, the cost-effectiveness of each intervention will be calculated. The findings of the proposed research have broad potential application and relevance to state quitlines, quitline service providers, and other purchasers of quitline services such as employers and insurers. Additionally, the study findings can potentially inform other telephone health behavior counseling programs.


Options:
A: Arm Label: Nicotine patch plus placebo gum; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Cognitive Behavior Therapy for alcohol and smoking cessation, Drug: Nicoderm CQ nicotine patch, Drug: Placebo gum | Arm Label: Nicotine patch plus active gum; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Cognitive Behavior Therapy for alcohol and smoking cessation, Drug: Nicoderm CQ nicotine patch, Drug: Nicotine gum - Nicorette® | Intervention Type: BEHAVIORAL; Name: Cognitive Behavior Therapy for alcohol and smoking cessation; Assigned to Arm(s): Nicotine patch plus active gum, Nicotine patch plus placebo gum | Intervention Type: DRUG; Name: Nicoderm CQ nicotine patch; Assigned to Arm(s): Nicotine patch plus active gum, Nicotine patch plus placebo gum | Intervention Type: DRUG; Name: Placebo gum; Assigned to Arm(s): Nicotine patch plus placebo gum | Intervention Type: DRUG; Name: Nicotine gum - Nicorette®; Assigned to Arm(s): Nicotine patch plus active gum
B: Arm Label: 2 Weeks of Nicotine Patch Only, No CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch | Arm Label: 2 Weeks of Nicotine Patch Only plus CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch, Behavioral: CMAC | Arm Label: 2 Wks Nicotine Patch+Nic Gum, No CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch, Drug: Nicotine gum | Arm Label: 2 Wks Nicotine Patch+Nic Gum plus CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch, Drug: Nicotine gum, Behavioral: CMAC | Arm Label: 6 Weeks of Nicotine Patch Only, No CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch | Arm Label: 6 Weeks of Nicotine Patch Only plus CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch, Behavioral: CMAC | Arm Label: 6 Wks Nicotine Patch+Nic Gum, No CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch, Drug: Nicotine gum | Arm Label: 6 Wks Nicotine Patch+Nic Gum plus CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch, Drug: Nicotine gum, Behavioral: CMAC | Intervention Type: DRUG; Name: Nicotine patch; Assigned to Arm(s): 2 Weeks of Nicotine Patch Only plus CMAC, 2 Weeks of Nicotine Patch Only, No CMAC, 2 Wks Nicotine Patch+Nic Gum plus CMAC, 2 Wks Nicotine Patch+Nic Gum, No CMAC, 6 Weeks of Nicotine Patch Only plus CMAC, 6 Weeks of Nicotine Patch Only, No CMAC, 6 Wks Nicotine Patch+Nic Gum plus CMAC, 6 Wks Nicotine Patch+Nic Gum, No CMAC | Intervention Type: DRUG; Name: Nicotine gum; Assigned to Arm(s): 2 Wks Nicotine Patch+Nic Gum plus CMAC, 2 Wks Nicotine Patch+Nic Gum, No CMAC, 6 Wks Nicotine Patch+Nic Gum plus CMAC, 6 Wks Nicotine Patch+Nic Gum, No CMAC | Intervention Type: BEHAVIORAL; Name: CMAC; Assigned to Arm(s): 2 Weeks of Nicotine Patch Only plus CMAC, 2 Wks Nicotine Patch+Nic Gum plus CMAC, 6 Weeks of Nicotine Patch Only plus CMAC, 6 Wks Nicotine Patch+Nic Gum plus CMAC
C: Arm Label: Effectiveness of Nicotine patch only; Type: EXPERIMENTAL; Interventions: Drug: Nicotine Patch | Arm Label: Effectiveness of Combination NRT; Type: EXPERIMENTAL; Interventions: Drug: Nicotine lozenge, Drug: Nicotine Patch | Arm Label: Effectiveness of Varenicline [Chantix]; Type: EXPERIMENTAL; Interventions: Drug: Varenicline | Intervention Type: DRUG; Name: Varenicline; Assigned to Arm(s): Effectiveness of Varenicline [Chantix] | Intervention Type: DRUG; Name: Nicotine lozenge; Assigned to Arm(s): Effectiveness of Combination NRT | Intervention Type: DRUG; Name: Nicotine Patch; Assigned to Arm(s): Effectiveness of Combination NRT, Effectiveness of Nicotine patch only
D: Arm Label: Extended Patch Treatment; Type: EXPERIMENTAL; Interventions: Drug: 24-weeks of nicotine patch | Arm Label: Standard Patch Treatment; Type: ACTIVE_COMPARATOR; Interventions: Drug: Standard Patch Treatment | Intervention Type: DRUG; Name: Standard Patch Treatment; Assigned to Arm(s): Standard Patch Treatment | Intervention Type: DRUG; Name: 24-weeks of nicotine patch; Assigned to Arm(s): Extended Patch Treatment

Answer: B