Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized, Double Blinded, Multi-center Phase III Confirmatory Study to Assess the Immunogenicity and Safety of NBP608 Compared to Zostavax in Healthy Adult Aged 50 and Over
Brief Summary: This study assesses non-inferiority by comparing GMR(Geometric Mean Ratio) of NBP608 to Zostavax which are evaluated by gpELISA (Glycoprotein Enzyme Linked Immunosorbent Assay). Total of 824 healthy subjects (412 subjects per treatment arm) aged 50 and over are enrolled, and each subject is administered with single dose of vaccine which is randomly assigned.


Options:
A: Arm Label: Co-Ad Group; Type: EXPERIMENTAL; Interventions: Biological: Herpes Zoster vaccine GSK 1437173A, Biological: Licensed pneumococcal polysaccharide conjugate vaccine (23-valent, adsorbed), Pneumovax 23™ | Arm Label: Control Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: Herpes Zoster vaccine GSK 1437173A, Biological: Licensed pneumococcal polysaccharide conjugate vaccine (23-valent, adsorbed), Pneumovax 23™ | Intervention Type: BIOLOGICAL; Name: Herpes Zoster vaccine GSK 1437173A; Assigned to Arm(s): Co-Ad Group, Control Group | Intervention Type: BIOLOGICAL; Name: Licensed pneumococcal polysaccharide conjugate vaccine (23-valent, adsorbed), Pneumovax 23™; Assigned to Arm(s): Co-Ad Group, Control Group
B: Arm Label: Full Dose Subcutaneous; Type: ACTIVE_COMPARATOR; Interventions: Biological: ZOSTAVAX™ (Zoster Vaccine Live) Full Dose Subcutaneous, Biological: Intradermal Placebo | Arm Label: 1/3 Dose Subcutaneous; Type: EXPERIMENTAL; Interventions: Biological: ZOSTAVAX™ (Zoster Vaccine Live) 1/3 Dose Subcutaneous, Biological: Intradermal Placebo | Arm Label: Full Dose Intradermal; Type: EXPERIMENTAL; Interventions: Biological: ZOSTAVAX™ (Zoster Vaccine Live) Full Dose Intradermal, Biological: Full Dose Intradermal Placebo | Arm Label: 1/3 Dose Intradermal; Type: EXPERIMENTAL; Interventions: Biological: ZOSTAVAX™ (Zoster Vaccine Live) Partial Doses Intradermal, Biological: Intradermal Placebo | Arm Label: 1/10 Dose Intradermal; Type: EXPERIMENTAL; Interventions: Biological: ZOSTAVAX™ (Zoster Vaccine Live) Partial Doses Intradermal, Biological: Intradermal Placebo | Arm Label: 1/27 Dose Intradermal; Type: EXPERIMENTAL; Interventions: Biological: ZOSTAVAX™ (Zoster Vaccine Live) Partial Doses Intradermal, Biological: Intradermal Placebo | Intervention Type: BIOLOGICAL; Name: ZOSTAVAX™ (Zoster Vaccine Live) Full Dose Subcutaneous; Assigned to Arm(s): Full Dose Subcutaneous | Intervention Type: BIOLOGICAL; Name: ZOSTAVAX™ (Zoster Vaccine Live) 1/3 Dose Subcutaneous; Assigned to Arm(s): 1/3 Dose Subcutaneous | Intervention Type: BIOLOGICAL; Name: ZOSTAVAX™ (Zoster Vaccine Live) Full Dose Intradermal; Assigned to Arm(s): Full Dose Intradermal | Intervention Type: BIOLOGICAL; Name: ZOSTAVAX™ (Zoster Vaccine Live) Partial Doses Intradermal; Assigned to Arm(s): 1/10 Dose Intradermal, 1/27 Dose Intradermal, 1/3 Dose Intradermal | Intervention Type: BIOLOGICAL; Name: Full Dose Intradermal Placebo; Assigned to Arm(s): Full Dose Intradermal | Intervention Type: BIOLOGICAL; Name: Intradermal Placebo; Assigned to Arm(s): 1/10 Dose Intradermal, 1/27 Dose Intradermal, 1/3 Dose Intradermal, 1/3 Dose Subcutaneous, Full Dose Subcutaneous
C: Arm Label: NBP608; Type: EXPERIMENTAL; Interventions: Biological: NBP608 | Arm Label: Zostavax; Type: ACTIVE_COMPARATOR; Interventions: Biological: Zostavax | Intervention Type: BIOLOGICAL; Name: NBP608; Assigned to Arm(s): NBP608 | Intervention Type: BIOLOGICAL; Name: Zostavax; Assigned to Arm(s): Zostavax
D: Arm Label: Co-Ad Group; Type: EXPERIMENTAL; Interventions: Biological: Herpes Zoster vaccine GSK 1437173A, Biological: GSK Biologicals' quadrivalent seasonal influenza vaccine FLU-D-QIV GSK2321138A | Arm Label: Control Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: Herpes Zoster vaccine GSK 1437173A, Biological: GSK Biologicals' quadrivalent seasonal influenza vaccine FLU-D-QIV GSK2321138A | Intervention Type: BIOLOGICAL; Name: Herpes Zoster vaccine GSK 1437173A; Assigned to Arm(s): Co-Ad Group, Control Group | Intervention Type: BIOLOGICAL; Name: GSK Biologicals' quadrivalent seasonal influenza vaccine FLU-D-QIV GSK2321138A; Assigned to Arm(s): Co-Ad Group, Control Group

Answer: C