Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Immunogenicity of the Human Rotavirus Vaccine (Rotarix™) at Varying Schedules, Doses, and Ages in Rural Ghana
Brief Summary: The purpose of this study is to determine whether giving the Human Rotavirus Vaccine on alternate dosing schedules will enhance the immune response to the vaccine in a low-resource, high-burden country in Africa. Alternate dosing schedules studied include giving the 2-dose vaccine schedule at a slightly older age and giving an additional dose of the vaccine.


Options:
A: Intervention Type: BIOLOGICAL; Name: Rotavirus (vaccine); Assigned to Arm(s): N/A
B: Arm Label: Bivalent OPV 2 week interval; Type: ACTIVE_COMPARATOR; Interventions: Biological: Bivalent OPV 2 week interval | Arm Label: Bivalent OPV 4 week interval; Type: ACTIVE_COMPARATOR; Interventions: Biological: Bivalent OPV 4 week interval | Arm Label: Monovalent OPV 2week interval; Type: ACTIVE_COMPARATOR; Interventions: Biological: Monovalent OPV 2 week interval | Arm Label: Monovalent OPV 4 week interval; Type: ACTIVE_COMPARATOR; Interventions: Biological: Monovalent OPV 4 week interval | Arm Label: Trivalent OPV 4 week interval; Type: ACTIVE_COMPARATOR; Interventions: Biological: Trivalent OPV 4 week interval | Intervention Type: BIOLOGICAL; Name: Bivalent OPV 2 week interval; Assigned to Arm(s): Bivalent OPV 2 week interval | Intervention Type: BIOLOGICAL; Name: Bivalent OPV 4 week interval; Assigned to Arm(s): Bivalent OPV 4 week interval | Intervention Type: BIOLOGICAL; Name: Monovalent OPV 2 week interval; Assigned to Arm(s): Monovalent OPV 2week interval | Intervention Type: BIOLOGICAL; Name: Monovalent OPV 4 week interval; Assigned to Arm(s): Monovalent OPV 4 week interval | Intervention Type: BIOLOGICAL; Name: Trivalent OPV 4 week interval; Assigned to Arm(s): Trivalent OPV 4 week interval
C: Arm Label: Rotavirus Vaccine at age 6 & 10 weeks; Type: ACTIVE_COMPARATOR; Interventions: Biological: Human Rotavirus Vaccine | Arm Label: Rotavirus vaccine at age 10 & 14 weeks; Type: EXPERIMENTAL; Interventions: Biological: Human Rotavirus Vaccine | Arm Label: Rotavirus vaccine at age 6,10,&14 weeks; Type: EXPERIMENTAL; Interventions: Biological: Human Rotavirus Vaccine | Intervention Type: BIOLOGICAL; Name: Human Rotavirus Vaccine; Assigned to Arm(s): Rotavirus Vaccine at age 6 & 10 weeks, Rotavirus vaccine at age 10 & 14 weeks, Rotavirus vaccine at age 6,10,&14 weeks
D: Arm Label: Group A (without rotavirus vaccine); Type: ACTIVE_COMPARATOR; Interventions: Biological: measles vaccine (MV), Biological: yellow fever vaccine (YFV), Biological: meningitis conjugate vaccine (PsA-TT-5μg) | Arm Label: Group B (with rotavirus vaccine); Type: EXPERIMENTAL; Interventions: Biological: pentavalent rotavirus vaccine (PRV), Biological: measles vaccine (MV), Biological: yellow fever vaccine (YFV), Biological: meningitis conjugate vaccine (PsA-TT-5μg) | Intervention Type: BIOLOGICAL; Name: pentavalent rotavirus vaccine (PRV); Assigned to Arm(s): Group B (with rotavirus vaccine) | Intervention Type: BIOLOGICAL; Name: measles vaccine (MV); Assigned to Arm(s): Group A (without rotavirus vaccine), Group B (with rotavirus vaccine) | Intervention Type: BIOLOGICAL; Name: yellow fever vaccine (YFV); Assigned to Arm(s): Group A (without rotavirus vaccine), Group B (with rotavirus vaccine) | Intervention Type: BIOLOGICAL; Name: meningitis conjugate vaccine (PsA-TT-5μg); Assigned to Arm(s): Group A (without rotavirus vaccine), Group B (with rotavirus vaccine)

Answer: C