Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: Hypothesis: Use of Bifidobacterium animalis subsp. lactis can effectively prevent common nosocomial (gastrointestinal and respiratory) infections. Nosocomial infection will be defined as infections which develop more than 48 hours after admission and they are not present or incubating on admission

This study is a prospective, randomized, double blind, placebo- controlled parallel study in children hospitalized at Children's hospital Zagreb.

The study will investigate the effect of supplementation with the probiotic strain Bifidobacterium animalis subsp. lactis on the incidence and duration of gastrointestinal and respiratory infections.

The test product is a sachet containing 1 gram of powder. The test product will contain minimum 1 billion CFU (colony forming units) probiotic per serving.

The placebo product is an identical product except for the absence of probiotics.

The study includes an intervention period lasting the length of the hospital stay.

The study product will be consumed daily in the morning together with breakfast.

The consumption of the study products will be taken under the surveillance of the physician.

Data on infections will be diagnosed by a physician and recorded in a CRF. The incidence of infections will be analyzed based on the information recorded in the CRF.


Options:
A: Arm Label: Cow's Milk; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Cow's milk | Arm Label: Follow-On Formula; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Follow-On Formula | Intervention Type: DIETARY_SUPPLEMENT; Name: Cow's milk; Assigned to Arm(s): Cow's Milk | Intervention Type: DIETARY_SUPPLEMENT; Name: Follow-On Formula; Assigned to Arm(s): Follow-On Formula
B: Arm Label: 1; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Placebo | Arm Label: Active 1; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Lactobacillus acidophilus NCFM | Arm Label: Active 2; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Combination of Lactobacillus acidophilus and Bifidobacterium lactis | Intervention Type: DIETARY_SUPPLEMENT; Name: Placebo; Assigned to Arm(s): 1 | Intervention Type: DIETARY_SUPPLEMENT; Name: Lactobacillus acidophilus NCFM; Assigned to Arm(s): Active 1 | Intervention Type: DIETARY_SUPPLEMENT; Name: Combination of Lactobacillus acidophilus and Bifidobacterium lactis; Assigned to Arm(s): Active 2
C: Arm Label: 1; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: low calcium milk of 180 ml | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: regular milk of 180 ml | Arm Label: 3; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: regular milk of 180 ml + probiotics | Arm Label: 4; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: regular milk of 180 ml + probiotics | Intervention Type: DIETARY_SUPPLEMENT; Name: low calcium milk of 180 ml; Assigned to Arm(s): 1 | Intervention Type: DIETARY_SUPPLEMENT; Name: regular milk of 180 ml; Assigned to Arm(s): 2 | Intervention Type: DIETARY_SUPPLEMENT; Name: regular milk of 180 ml + probiotics; Assigned to Arm(s): 3 | Intervention Type: DIETARY_SUPPLEMENT; Name: regular milk of 180 ml + probiotics; Assigned to Arm(s): 4
D: Arm Label: Bifidobacterium animalis subsp. lactis; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Bifidobacterium animalis subsp. lactis | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: N/A | Intervention Type: DIETARY_SUPPLEMENT; Name: Bifidobacterium animalis subsp. lactis; Assigned to Arm(s): Bifidobacterium animalis subsp. lactis

Answer: D