Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Randomized Phase III Trial Comparing an Association of Hormonal Treatment and Docetaxel Versus the Hormonal Treatment Alone in Metastatic Prostate Cancers
Brief Summary: RATIONALE: Androgens can cause the growth of prostate cancer cells. Drugs, such as goserelin, may stop the adrenal glands from making androgens. Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving hormone therapy together with docetaxel may be an effective treatment for prostate cancer. It is not yet known whether giving hormone therapy together with docetaxel is more effective than hormone therapy alone in treating prostate cancer.

PURPOSE: This randomized phase III trial is studying hormone therapy and docetaxel to see how well they work compared to hormone therapy alone in treating patients with metastatic prostate cancer.


Options:
A: Arm Label: Abiraterone acetate + Prednisone + ADT; Type: EXPERIMENTAL; Interventions: Drug: Abiraterone acetate, Drug: Prednisone, Other: Androgen deprivation therapy (ADT) | Arm Label: Placebo + Androgen Deprivation Therapy (ADT); Type: PLACEBO_COMPARATOR; Interventions: Other: Androgen deprivation therapy (ADT), Drug: Abiraterone acetate Placebo, Drug: Prednisone Placebo | Intervention Type: DRUG; Name: Abiraterone acetate; Assigned to Arm(s): Abiraterone acetate + Prednisone + ADT | Intervention Type: DRUG; Name: Prednisone; Assigned to Arm(s): Abiraterone acetate + Prednisone + ADT | Intervention Type: OTHER; Name: Androgen deprivation therapy (ADT); Assigned to Arm(s): Abiraterone acetate + Prednisone + ADT, Placebo + Androgen Deprivation Therapy (ADT) | Intervention Type: DRUG; Name: Abiraterone acetate Placebo; Assigned to Arm(s): Placebo + Androgen Deprivation Therapy (ADT) | Intervention Type: DRUG; Name: Prednisone Placebo; Assigned to Arm(s): Placebo + Androgen Deprivation Therapy (ADT)
B: Arm Label: Androgen-Deprivation Therapy and Docetaxel; Type: EXPERIMENTAL; Interventions: Drug: androgen-deprivation therapy, Drug: docetaxel | Arm Label: Androgen-Deprivation Therapy alone; Type: ACTIVE_COMPARATOR; Interventions: Drug: androgen-deprivation therapy | Intervention Type: DRUG; Name: androgen-deprivation therapy; Assigned to Arm(s): Androgen-Deprivation Therapy alone, Androgen-Deprivation Therapy and Docetaxel | Intervention Type: DRUG; Name: docetaxel; Assigned to Arm(s): Androgen-Deprivation Therapy and Docetaxel
C: Arm Label: Arm I; Type: EXPERIMENTAL; Interventions: Drug: docetaxel, Drug: prednisone | Arm Label: Arm II; Type: EXPERIMENTAL; Interventions: Drug: docetaxel, Drug: prednisone | Intervention Type: DRUG; Name: docetaxel; Assigned to Arm(s): Arm I, Arm II | Intervention Type: DRUG; Name: prednisone; Assigned to Arm(s): Arm I, Arm II
D: Arm Label: Hormonotherapy + chemotherapy; Type: EXPERIMENTAL; Interventions: Drug: antiandrogen therapy, Drug: docetaxel, Drug: goserelin acetate, Procedure: orchiectomy | Arm Label: Hormonotherapy alone; Type: ACTIVE_COMPARATOR; Interventions: Drug: antiandrogen therapy, Drug: goserelin acetate, Procedure: orchiectomy | Intervention Type: DRUG; Name: antiandrogen therapy; Assigned to Arm(s): Hormonotherapy + chemotherapy, Hormonotherapy alone | Intervention Type: DRUG; Name: docetaxel; Assigned to Arm(s): Hormonotherapy + chemotherapy | Intervention Type: DRUG; Name: goserelin acetate; Assigned to Arm(s): Hormonotherapy + chemotherapy, Hormonotherapy alone | Intervention Type: PROCEDURE; Name: orchiectomy; Assigned to Arm(s): Hormonotherapy + chemotherapy, Hormonotherapy alone

Answer: D