Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effect of Micronutrients and Exercise During Pregnancy on Factors Related With Non-Transmissible Chronic Diseases
Brief Summary: At the moment, most of efforts to prevent non-transmissible chronic diseases at population level have been centered in promoting healthful behaviors like physical activity, consumption of fruits and vegetables, and discouraging from the consumption of tobacco and alcohol in adult population, but the results have been little hopeful. In the last years, manifold studies have indicated the relation between metabolic alterations and of the fetal growth with the development of non-transmissible chronic diseases in adult age. More recently, it has been proposed that maternal factors (endothelial function, oxidative stress and alterations in adipokines) and placental ones (mitochondrial dysfunction) are the precursory mechanisms of fetal metabolic alterations and of the later development of non-transmissible chronic diseases. Also, it has been suggested that possibly supplementation with micronutrients and the physical exercise during the gestation can regulate these maternal and placental factors. For the reasons just mentioned, it is necessary to clarify if these proposed factors are related to fetal metabolic alterations and if the supplementation during the gestation with micronutrients and/or the physical exercise can regulate them, which would be an early and novel alternative to fortify the prevention of non-transmissible chronic diseases in the population.

Purpose

1. To evaluate the effect of associated both the maternal and placental metabolic factors to non-transmissible chronic diseases in newborn.
2. To evaluate the effect of the physical exercise and the complementation with micronutrients during the pregnancy either in the endothelial function, the levels of adipokines, the oxidative stress of the mother and the newborn, as in the placental mitochondrial function and the anthropometry of newborn.


Options:
A: Arm Label: A; Type: EXPERIMENTAL; Interventions: Procedure: Sleep deprivation, Procedure: Light therapy, Procedure: Diurnal rhythms, Drug: duloxetine | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Exercise, Drug: duloxetine | Intervention Type: PROCEDURE; Name: Sleep deprivation; Assigned to Arm(s): A | Intervention Type: PROCEDURE; Name: Light therapy; Assigned to Arm(s): A | Intervention Type: PROCEDURE; Name: Diurnal rhythms; Assigned to Arm(s): A | Intervention Type: BEHAVIORAL; Name: Exercise; Assigned to Arm(s): B | Intervention Type: DRUG; Name: duloxetine; Assigned to Arm(s): A | Intervention Type: DRUG; Name: duloxetine; Assigned to Arm(s): B
B: Arm Label: 1; Type: OTHER; Interventions: Behavioral: Regular aerobic physical exercise | Arm Label: 2; Type: OTHER; Interventions: Dietary Supplement: Micronutrients | Arm Label: 3; Type: OTHER; Interventions: Behavioral: Regular aerobic physical exercise, Dietary Supplement: Micronutrients | Arm Label: 4; Type: PLACEBO_COMPARATOR; Interventions: Other: Activities of daily living + placebo | Intervention Type: BEHAVIORAL; Name: Regular aerobic physical exercise; Assigned to Arm(s): 1, 3 | Intervention Type: DIETARY_SUPPLEMENT; Name: Micronutrients; Assigned to Arm(s): 2, 3 | Intervention Type: OTHER; Name: Activities of daily living + placebo; Assigned to Arm(s): 4
C: Arm Label: Enhanced Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Staged Care Management; Type: EXPERIMENTAL; Interventions: Behavioral: Medication Care Management (MCM), Behavioral: Cognitive-Behavioral Therapy (CBT) | Intervention Type: BEHAVIORAL; Name: Medication Care Management (MCM); Assigned to Arm(s): Staged Care Management | Intervention Type: BEHAVIORAL; Name: Cognitive-Behavioral Therapy (CBT); Assigned to Arm(s): Staged Care Management
D: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Weight loss treatment, Behavioral: Health education counseling | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Behavioral: Weight loss treatment, Behavioral: Behavior therapy for depression | Intervention Type: BEHAVIORAL; Name: Weight loss treatment; Assigned to Arm(s): 1, 2 | Intervention Type: BEHAVIORAL; Name: Behavior therapy for depression; Assigned to Arm(s): 2 | Intervention Type: BEHAVIORAL; Name: Health education counseling; Assigned to Arm(s): 1

Answer: B