Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized Trial of Hypofractionated Radiotherapy Post-Lumpectomy in Women With Node Negative Breast Cancer
Brief Summary: To determine if hypofractionated radiotherapy to the whole breast (4,250 cGy/16 fractions over 22 days) is equally effective to standard fractionated radiotherapy (5,000 cGy/25 fractions over 35 days) in women with node negative breast cancer who have undergone lumpectomy.

The primary outcome is local breast recurrence and secondary outcomes include morbidity and cost effectiveness.


Options:
A: Arm Label: Hypofractionated whole breast radiation; Type: EXPERIMENTAL; Interventions: Radiation: Hypofractionated whole breast radiation schedule | Arm Label: Conventional whole breast radiation; Type: ACTIVE_COMPARATOR; Interventions: Radiation: Conventional whole breast radiation schedule | Intervention Type: RADIATION; Name: Conventional whole breast radiation schedule; Assigned to Arm(s): Conventional whole breast radiation | Intervention Type: RADIATION; Name: Hypofractionated whole breast radiation schedule; Assigned to Arm(s): Hypofractionated whole breast radiation
B: Arm Label: Arm I (HF-WBI); Type: EXPERIMENTAL; Interventions: Radiation: External Beam Radiation Therapy, Radiation: Hypofractionated Radiation Therapy, Other: Laboratory Biomarker Analysis, Other: Quality-of-Life Assessment, Other: Questionnaire Administration, Radiation: Whole Breast Irradiation | Arm Label: Arm II (CF-WBI); Type: ACTIVE_COMPARATOR; Interventions: Radiation: External Beam Radiation Therapy, Other: Laboratory Biomarker Analysis, Other: Quality-of-Life Assessment, Other: Questionnaire Administration, Radiation: Whole Breast Irradiation | Intervention Type: RADIATION; Name: External Beam Radiation Therapy; Assigned to Arm(s): Arm I (HF-WBI) | Intervention Type: RADIATION; Name: External Beam Radiation Therapy; Assigned to Arm(s): Arm II (CF-WBI) | Intervention Type: RADIATION; Name: Hypofractionated Radiation Therapy; Assigned to Arm(s): Arm I (HF-WBI) | Intervention Type: OTHER; Name: Laboratory Biomarker Analysis; Assigned to Arm(s): Arm I (HF-WBI), Arm II (CF-WBI) | Intervention Type: OTHER; Name: Quality-of-Life Assessment; Assigned to Arm(s): Arm I (HF-WBI), Arm II (CF-WBI) | Intervention Type: OTHER; Name: Questionnaire Administration; Assigned to Arm(s): Arm I (HF-WBI), Arm II (CF-WBI) | Intervention Type: RADIATION; Name: Whole Breast Irradiation; Assigned to Arm(s): Arm I (HF-WBI) | Intervention Type: RADIATION; Name: Whole Breast Irradiation; Assigned to Arm(s): Arm II (CF-WBI)
C: Arm Label: Conventional radiotherapy; Type: ACTIVE_COMPARATOR; Interventions: Radiation: Conventional radiotherapy | Arm Label: Tomotherapy; Type: EXPERIMENTAL; Interventions: Radiation: Tomotherapy | Intervention Type: RADIATION; Name: Conventional radiotherapy; Assigned to Arm(s): Conventional radiotherapy | Intervention Type: RADIATION; Name: Tomotherapy; Assigned to Arm(s): Tomotherapy
D: Arm Label: Arm 1: adriamycin + cyclophosphamide then taxol; Type: ACTIVE_COMPARATOR; Interventions: Drug: adriamycin, Drug: cyclophosphamide, Drug: taxol | Arm Label: Arm 2: adriamycin + cyclophosphamide then taxol + herceptin; Type: EXPERIMENTAL; Interventions: Biological: herceptin, Drug: adriamycin, Drug: cyclophosphamide, Drug: taxol | Intervention Type: BIOLOGICAL; Name: herceptin; Assigned to Arm(s): Arm 2: adriamycin + cyclophosphamide then taxol + herceptin | Intervention Type: DRUG; Name: adriamycin; Assigned to Arm(s): Arm 1: adriamycin + cyclophosphamide then taxol, Arm 2: adriamycin + cyclophosphamide then taxol + herceptin | Intervention Type: DRUG; Name: cyclophosphamide; Assigned to Arm(s): Arm 1: adriamycin + cyclophosphamide then taxol, Arm 2: adriamycin + cyclophosphamide then taxol + herceptin | Intervention Type: DRUG; Name: taxol; Assigned to Arm(s): Arm 1: adriamycin + cyclophosphamide then taxol, Arm 2: adriamycin + cyclophosphamide then taxol + herceptin

Answer: A