Please select the eligibility criteria that correspond to the clinical trial below.
Title: Tailored Activity to Improve Affect in Dementia
Brief Summary: Specific Aims

1. Establish a preliminary effect size for the impact of the intervention on depressive affect and agitated behaviors in persons with dementia in 4 months
2. Evaluate acceptance of and engagement in activities in persons with dementia
3. Establish a preliminary effect size for the impact of the intervention on caregiver burden, depressive symptoms, and mastery at 4 months.
4. Evaluate caregiver skills acquisition, acceptance of and compliance to intervention techniques.


Options:
A: Inclusion Criteria:

Inclusion Criteria for Veterans with dementia include:

* English speaking
* diagnosed with dementia as above
* able to participate in at least two activities of daily living

  * ADLs - bathing
  * dressing
  * grooming
  * toileting
  * transferring from bed to chair
* not currently participating in any other dementia-related intervention.
* If the Veteran with dementia is on any of four classes of psychotropic medications:

  * antidepressant
  * benzodiazepines
  * antipsychotic
  * anti-convulsant
  * an anti-dementia medication (memantine or a cholinesterase inhibitor)
* We will require that he/she have been on a stable dose for 60 days prior to enrollment to minimize possible confounding effects of concomitant medications (the typical time frame used in clinical trials).
* Caregivers of Veterans must be:

  * English speaking
  * self-identify as the primary member of the family caring (hands-on or supervision) for the Veteran and 21 years of age or older (male or female)
  * living with the Veteran
  * accessible by telephone to schedule interview, intervention sessions and follow-up interviews
  * planning to live in area for 8 months (to reduce loss to follow-up)
  * indicate willingness to learn activity use
  * report one or more NPS in the Veteran in the past month
  * not currently participating in any other caregiver-related intervention.
* Finally, we will require that caregivers taking a psychotropic medication (antidepressant, benzodiazepines, antipsychotic, or anti-convulsant) at time of telephone screen be on a stable dose of the medication for 60 days prior to enrollment.

Exclusion Criteria:

* Non English speaking
* Non-Veteran
* No caregiver
* No diagnosis of dementia
B: Inclusion Criteria: Inclusion criteria pertain to both the person with dementia (PwD) and the caregiver (CG) such that if either is eligible but the other is not, the dyad is not enrolled.

* PwD and caregiver are English speaking
* Diagnosed with probable dementia
* PwD is able to participate in at least 2 activities of daily living (bathing, dressing, grooming, toileting, transferring from bed to chair)
* Person with dementia exhibits agitated or aggressive behaviors
* If PwD is on a psychotropic medication he/she must be on a stable dose for at least 60 days
* CG is at least 21 years old
* CG lives with or within 5 miles of the person with dementia
* CG is accessible by telephone to schedule interviews and sessions
* CG is planning to live in the area for at least 6 months
* If the CG is on a psychotropic medication he/she must be on a stable dose for at least 60 days

Exclusion Criteria:Exclusion criteria pertain to both the person with dementia and the caregiver such that if either is eligible but the other is not, the dyad is not enrolled.

* PwD has a history of schizophrenia or bipolar disorder
* Dementia is secondary to probable head trauma
* PwD is not responsive to environment (e.g., unable to understand short commands or recognize a person coming in/out of the room).
* the CG is currently involved in another clinical trial of psychosocial or educational interventions
* the CG is planning to place PwD in a nursing home within 6 months.
* dyads will be excluded if either CG or PwD: 1) has a terminal illness with life expectancy \< 6 months, 2) is in active treatment for cancer, or 3) has had \> 3 acute medical hospitalizations in past year.
C: Inclusion Criteria:

* Care Recipient
* English Speaking
* NINCDS-ADRDA diagnosis\[physician generated of dementia or mini-mental state examination score of less than or equal to 23;3\] Able to feel self; and participates in at least 2 other activities of daily living\[ADLs-Bathing, Dressing, Grooming, Toileting, Transferring from bed to chair\] As reported by caregiver.
* Caregiver
* English Speaking
* Family member 21 years of age or older \[male or female\]
* Lives with Care Recipient
* Has telephone in the home
* Plans to live in area for 8 months
* Indicated willingness to learn new approaches by which to engage care recipient in meaningful activities
* Provides 4 or more hours a day directly caring or providing for care recipient

Exclusion Criteria:

* Care Recipient
* Has Schizophrenia or Bi-Polar Disorder
* Their Dementia is secondary to probable head trauma
* Their MMSE score is equal to zero and they are bed bound, defined as confinement to bed or chair for at least 22 hours a day for at least 4 of 7 days
* They are not responsive to their environment
* Caregiver
* Are currently involved in another clinical trial of psycho-social or educational interventions for caregivers
* Are planning to place their family member in a nursing home within the next 8 months. Also, the care recipient/caregiver dyad will be excluded if either caregiver or care recipient: 1) has a terminal illness with life expectancy less than 8 months 2)is in active treatment for cancer or 3) has had greater than 3 acute medical hospitalizations within the past year.
D: Inclusion Criteria:

* Active client in publicly-funded home care program; Diagnosis of Alzheimer's disease or other dementia OR \>=4 errors on the Mental Status Questionnaire; speaks or understands English

Exclusion Criteria:

* Diagnosed schizophrenia or bipolar disorder; bedbound; participation in experimental drug study to treat agitation; home environment deemed unsafe or unsanitary.

Answer: C