Please select the eligibility criteria that correspond to the clinical trial below.
Title: The "START" (a Streamlined ART Initiation Strategy) Study
Brief Summary: START is clinic-level (not individual-patient) intervention to catalyze the process of ART initiation among HIV-infected adults who meet CD4-based criteria for combination ART (e.g., adults with a CD4 T cell level \< 350/ul). The three START components are: (1) real-time point-of-care CD4 testing using the Alere PIMA platform to ascertain treatment eligibility in real time at first presentation to care, (2) targeted knowledge transfer (i.e., dissemination) of recent scientific evidence regarding effects rapid ART initiation on survival to front line health care workers; and 3) feedback and reporting to clinic and providers. There three components represent empirically validated steps in the PRECEED implementation model.


Options:
A: Inclusion Criteria:

* Adult patients (\>18 years)
* Tested HIV-positive at study site's outpatient testing service or antenatal clinic on day of study enrollment or previously tested HIV-positive but making first visit to study site for HIV-related care or antenatal care for the current pregnancy
* Eligible for antiretroviral therapy under prevailing South African guidelines

Exclusion Criteria:

* Currently or previously on ART (three-drug combination; previous PMTCT regimen exposure for an earlier pregnancy is not an exclusion criterion)
* Stated intention to seek further HIV or antenatal care at another site, not at the study site
* Not physically or emotionally able to participate in the study, in the opinion of the investigators
* Not willing or able to provide written informed consent to participate in the study
* Previously screened for the same study
B: Inclusion Criteria:

* 18 years of age or older
* Testing HIV positive at the largest-volume HIV point of testing (other than prevention of mother-to-child transmission or tuberculosis) at SU with written proof of test result
* Agreeing to be referred to the HIV care services associated with the SU
* Agreeing to provide locator information
* Agreeing to adhere to study procedures, including a baseline interview, interviews 1 and 12 months after study enrollment, and extraction of data from the HIV care and treatment electronic database
* Able to provide informed consent

Exclusion Criteria:

* Being pregnant at study enrollment
* Planning on leaving the community where they currently reside in the next 12 months
* Enrolled in HIV care in the past 6 months at any clinic
* Initiated ART (for any duration) in the past 6 months at any clinic
* Currently on ART
* Does not speak or understand Portuguese or Xitswa/Matswa
C: Inclusion Criteria:

* All MJAP-supported clinics in Kampala and Mbarara Districts

Exclusion Criteria:

* None.
D: Inclusion Criteria:

* HIV infection newly diagnosed during community-based HTC-campaigns
* Never been on triple-ART
* Lives and/or works in the district of Butha-Buthe and declares to seek follow-up at one of the 6 health facilities involved in the study
* Signed written informed consent

Exclusion Criteria:

* Pregnant or breast-feeding
* Already enrolled in chronic care for another disease, such as tuberculosis or diabetes
* Clinical WHO-stage 4 or active tuberculosis
* Positive cryptococcal antigen test

Answer: C