TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized, Double-blind, Multicenter, Active-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Subjects With Treatment-resistant Depression
Brief Summary: The purpose of this study is to compare the efficacy and safety of switching treatment-resistant depression (TRD) subjects from a prior antidepressant treatment (to which they have not responded) to either intranasal esketamine plus a new oral antidepressant or switching to a new oral antidepressant plus intranasal placebo.


Options:
A: Arm Label: sarcosine; Type: EXPERIMENTAL; Interventions: Drug: sarcosine | Arm Label: citalopram; Type: ACTIVE_COMPARATOR; Interventions: Drug: citalopram | Intervention Type: DRUG; Name: citalopram; Assigned to Arm(s): citalopram | Intervention Type: DRUG; Name: sarcosine; Assigned to Arm(s): sarcosine
B: Arm Label: Ketamine; Type: EXPERIMENTAL; Interventions: Drug: Ketamine | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Intervention Type: DRUG; Name: Ketamine; Assigned to Arm(s): Ketamine | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Placebo
C: Arm Label: Intranasal Esketamine plus oral antidepressant; Type: EXPERIMENTAL; Interventions: Drug: Esketamine, Drug: Duloxetine (Oral Antidepressant), Drug: Escitalopram (Oral antidepressant), Drug: Sertraline (Oral Antidepressant), Drug: Venlafaxine Extended Release (XR) (Oral Antidepressant) | Arm Label: Placebo plus oral antidepressant; Type: ACTIVE_COMPARATOR; Interventions: Drug: Placebo, Drug: Duloxetine (Oral Antidepressant), Drug: Escitalopram (Oral antidepressant), Drug: Sertraline (Oral Antidepressant), Drug: Venlafaxine Extended Release (XR) (Oral Antidepressant) | Intervention Type: DRUG; Name: Esketamine; Assigned to Arm(s): Intranasal Esketamine plus oral antidepressant | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo plus oral antidepressant | Intervention Type: DRUG; Name: Duloxetine (Oral Antidepressant); Assigned to Arm(s): Intranasal Esketamine plus oral antidepressant, Placebo plus oral antidepressant | Intervention Type: DRUG; Name: Escitalopram (Oral antidepressant); Assigned to Arm(s): Intranasal Esketamine plus oral antidepressant, Placebo plus oral antidepressant | Intervention Type: DRUG; Name: Sertraline (Oral Antidepressant); Assigned to Arm(s): Intranasal Esketamine plus oral antidepressant, Placebo plus oral antidepressant | Intervention Type: DRUG; Name: Venlafaxine Extended Release (XR) (Oral Antidepressant); Assigned to Arm(s): Intranasal Esketamine plus oral antidepressant, Placebo plus oral antidepressant
D: Arm Label: AZD6765 (150 mg) / Placebo; Type: EXPERIMENTAL; Interventions: Drug: AZD6765 | Arm Label: Placebo / AZD6765 (150 mg); Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo to AZD6765 | Intervention Type: DRUG; Name: AZD6765; Assigned to Arm(s): AZD6765 (150 mg) / Placebo | Intervention Type: DRUG; Name: Placebo to AZD6765; Assigned to Arm(s): Placebo / AZD6765 (150 mg)

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Treatment of Calcific Tendinitis of the Rotator Cuff - a Multi-centre, Randomized and Sham Controlled Trial (KALK Study)
Brief Summary: The purpose of this study is to determine whether the combination of removal of the calcification in calcific tendinitis of the shoulder (supraspinatus and/or infraspinatus tendon) by aspiration with a needle and syringe (barbotage) and a corticosteroid injection is more effective than corticosteroid or sham injection alone.


Options:
A: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Physical therapy method called Supervised Exercises | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Radial Extracorporeal Shockwave Therapy | Intervention Type: PROCEDURE; Name: Physical therapy method called Supervised Exercises; Assigned to Arm(s): A | Intervention Type: PROCEDURE; Name: Radial Extracorporeal Shockwave Therapy; Assigned to Arm(s): B
B: Arm Label: Active physiotherapy; Type: EXPERIMENTAL; Interventions: Procedure: Physiotherapy program | Arm Label: Placebo physiotherapy; Type: PLACEBO_COMPARATOR; Interventions: Procedure: Placebo physiotherapy treatment | Intervention Type: PROCEDURE; Name: Physiotherapy program; Assigned to Arm(s): Active physiotherapy | Intervention Type: PROCEDURE; Name: Placebo physiotherapy treatment; Assigned to Arm(s): Placebo physiotherapy
C: Arm Label: Arthroscopic Sub-acromial Decompression; Type: EXPERIMENTAL; Interventions: Procedure: Arthroscopic Sub-acromial Decompression Surgery | Arm Label: Shoulder Arthroscopy; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Shoulder Arthroscopy | Arm Label: Active Monitoring with Specialist Reassessment; Type: OTHER; Interventions: Other: Active Monitoring with Specialist Reassessment | Intervention Type: PROCEDURE; Name: Arthroscopic Sub-acromial Decompression Surgery; Assigned to Arm(s): Arthroscopic Sub-acromial Decompression | Intervention Type: PROCEDURE; Name: Shoulder Arthroscopy; Assigned to Arm(s): Shoulder Arthroscopy | Intervention Type: OTHER; Name: Active Monitoring with Specialist Reassessment; Assigned to Arm(s): Active Monitoring with Specialist Reassessment
D: Arm Label: Barbotage; Type: EXPERIMENTAL; Interventions: Procedure: Barbotage | Arm Label: Corticosteroid injection; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Corticosteroid injection | Arm Label: Lidocain injection (sham); Type: SHAM_COMPARATOR; Interventions: Procedure: Lidocain injection (sham) | Intervention Type: PROCEDURE; Name: Barbotage; Assigned to Arm(s): Barbotage | Intervention Type: PROCEDURE; Name: Corticosteroid injection; Assigned to Arm(s): Corticosteroid injection | Intervention Type: PROCEDURE; Name: Lidocain injection (sham); Assigned to Arm(s): Lidocain injection (sham)

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism (RESCUE)-Japan Randomized Controlled Trial
Brief Summary: The aim of this study is to clarify the efficacy of the endovascular treatment for acute ischemic stroke patients with large vessel occlusion and are not respond to intravenous recombinant tissue plasminogen activator (rt-PA) therapy.


Options:
A: Arm Label: Higher Systolic Blood Pressure (SBP) Target; Type: EXPERIMENTAL; Interventions: Drug: Nicardipine, Drug: Labetalol, Drug: Hydralazine | Arm Label: Lower SBP (<160 mmHg) Target; Type: EXPERIMENTAL; Interventions: Drug: Nicardipine, Drug: Labetalol, Drug: Hydralazine | Arm Label: Lower SBP (<140mmHg) Target; Type: EXPERIMENTAL; Interventions: Drug: Nicardipine, Drug: Labetalol, Drug: Hydralazine | Intervention Type: DRUG; Name: Nicardipine; Assigned to Arm(s): Higher Systolic Blood Pressure (SBP) Target, Lower SBP (<140mmHg) Target, Lower SBP (<160 mmHg) Target | Intervention Type: DRUG; Name: Labetalol; Assigned to Arm(s): Higher Systolic Blood Pressure (SBP) Target, Lower SBP (<140mmHg) Target, Lower SBP (<160 mmHg) Target | Intervention Type: DRUG; Name: Hydralazine; Assigned to Arm(s): Higher Systolic Blood Pressure (SBP) Target, Lower SBP (<140mmHg) Target, Lower SBP (<160 mmHg) Target
B: Arm Label: Intervention group; Type: EXPERIMENTAL; Interventions: Other: Intensive BP lowering | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Intensive BP lowering; Assigned to Arm(s): Intervention group
C: Arm Label: Low-dose rtPA (Recruitment completed in August 2015); Type: EXPERIMENTAL; Interventions: Drug: Low-dose rtPA | Arm Label: Standard-dose rtPA (Recruitment completed in August 2015); Type: ACTIVE_COMPARATOR; Interventions: Drug: Standard-dose rtPA | Arm Label: Early intensive BP lowering; Type: EXPERIMENTAL; Interventions: Other: Intensive blood pressure (BP) lowering | Arm Label: Control / guideline-based BP management; Type: ACTIVE_COMPARATOR; Interventions: Other: BP management policies | Intervention Type: DRUG; Name: Low-dose rtPA; Assigned to Arm(s): Low-dose rtPA (Recruitment completed in August 2015) | Intervention Type: DRUG; Name: Standard-dose rtPA; Assigned to Arm(s): Standard-dose rtPA (Recruitment completed in August 2015) | Intervention Type: OTHER; Name: Intensive blood pressure (BP) lowering; Assigned to Arm(s): Early intensive BP lowering | Intervention Type: OTHER; Name: BP management policies; Assigned to Arm(s): Control / guideline-based BP management
D: Arm Label: Group with endovascular treatment; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Rescue endovascular therapy | Arm Label: Group without endovascular treatment; Type: ACTIVE_COMPARATOR; Interventions: Procedure: No endovascular therapy | Intervention Type: PROCEDURE; Name: Rescue endovascular therapy; Assigned to Arm(s): Group with endovascular treatment | Intervention Type: PROCEDURE; Name: No endovascular therapy; Assigned to Arm(s): Group without endovascular treatment

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism (RESCUE)-Japan Randomized Controlled Trial
Brief Summary: The aim of this study is to clarify the efficacy of the endovascular treatment for acute ischemic stroke patients with large vessel occlusion and are not respond to intravenous recombinant tissue plasminogen activator (rt-PA) therapy.


Options:
A: Arm Label: Trevo Thrombectomy Procedure; Type: EXPERIMENTAL; Interventions: Device: Trevo Thrombectomy Procedure, Other: Medical Management | Arm Label: Medical Management; Type: ACTIVE_COMPARATOR; Interventions: Other: Medical Management | Intervention Type: DEVICE; Name: Trevo Thrombectomy Procedure; Assigned to Arm(s): Trevo Thrombectomy Procedure | Intervention Type: OTHER; Name: Medical Management; Assigned to Arm(s): Medical Management, Trevo Thrombectomy Procedure
B: Arm Label: Best medical therapy; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Endovascular treatment; Type: EXPERIMENTAL; Interventions: Device: Endovascular Mechanical Thrombectomy | Intervention Type: DEVICE; Name: Endovascular Mechanical Thrombectomy; Assigned to Arm(s): Endovascular treatment
C: Arm Label: Group with endovascular treatment; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Rescue endovascular therapy | Arm Label: Group without endovascular treatment; Type: ACTIVE_COMPARATOR; Interventions: Procedure: No endovascular therapy | Intervention Type: PROCEDURE; Name: Rescue endovascular therapy; Assigned to Arm(s): Group with endovascular treatment | Intervention Type: PROCEDURE; Name: No endovascular therapy; Assigned to Arm(s): Group without endovascular treatment
D: Arm Label: intravenous tissue plasminogen activator; Type: EXPERIMENTAL; Interventions: Drug: Tissue Plasminogen Activator (Alteplase) | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Tissue Plasminogen Activator (Alteplase); Assigned to Arm(s): intravenous tissue plasminogen activator | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effect of Physical Exercise Program on Fetoplacental Growth: a Randomized Controlled Trial
Brief Summary: The aim of this study is to examine the effect of a supervised physical exercise program during pregnancy on fetoplacental growth.


Options:
A: Arm Label: Lifestyle intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Physical Exercise / Physical Activity | Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Physical Exercise / Physical Activity; Assigned to Arm(s): Lifestyle intervention
B: Arm Label: stabilization exercises; Type: EXPERIMENTAL; Interventions: Other: Stabilization exercise | Arm Label: control group; Type: EXPERIMENTAL; Interventions: Other: Control group | Intervention Type: OTHER; Name: Stabilization exercise; Assigned to Arm(s): stabilization exercises | Intervention Type: OTHER; Name: Control group; Assigned to Arm(s): control group
C: Arm Label: Exercise group; Type: EXPERIMENTAL; Interventions: Other: Exercise classes with pelvic floor muscle training | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Exercise classes with pelvic floor muscle training; Assigned to Arm(s): Exercise group
D: Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Exercise Group; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise Group | Intervention Type: BEHAVIORAL; Name: Exercise Group; Assigned to Arm(s): Exercise Group

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effect of Physical Exercise Program on Fetoplacental Growth: a Randomized Controlled Trial
Brief Summary: The aim of this study is to examine the effect of a supervised physical exercise program during pregnancy on fetoplacental growth.


Options:
A: Arm Label: Rééducation; Type: EXPERIMENTAL; Interventions: Other: Pelvic floor muscle training with physiotherapist, Other: Written information about kegel exercises | Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Other: Written information about kegel exercises | Intervention Type: OTHER; Name: Pelvic floor muscle training with physiotherapist; Assigned to Arm(s): Rééducation | Intervention Type: OTHER; Name: Written information about kegel exercises; Assigned to Arm(s): Control, Rééducation
B: Arm Label: Pelvic floor training; Type: ACTIVE_COMPARATOR; Interventions: Other: Pelvic floor training | Arm Label: Literature-only group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Pelvic floor training; Assigned to Arm(s): Pelvic floor training
C: Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Exercise Group; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise Group | Intervention Type: BEHAVIORAL; Name: Exercise Group; Assigned to Arm(s): Exercise Group
D: Arm Label: Perineal muscle training; Type: EXPERIMENTAL; Interventions: Behavioral: Perineal muscle training | Arm Label: Usual prental care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Perineal muscle training; Assigned to Arm(s): Perineal muscle training

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: An Innovative Caregiver Tool to Assess and Manage Behavioral Symptoms of Dementia
Brief Summary: Behavioral symptoms that commonly occur with dementia are associated with increased health care utilization and can lead to challenges for the person living with dementia and their caregivers. Caregivers need knowledge and skills to monitor these behaviors, to identify what triggers them, and to learn how to use proven, practical medication-free strategies to prevent and manage the behaviors. The purpose of this study is to develop and test the WeCareAdvisor, a customized, internet-based computer tool for family caregivers that helps them to assess, manage and track behavioral symptoms and their contributing factors (e.g., pain, sleep disturbance), and that provides tailored strategies for in-home, medication-free behavior management. This study is a collaboration between researchers at the University of Michigan and Johns Hopkins University.


Options:
A: Arm Label: Immediately Receive Tool; Type: EXPERIMENTAL; Interventions: Behavioral: Immediately Receive Tool | Arm Label: One Month Delay; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: One Month Delay | Intervention Type: BEHAVIORAL; Name: Immediately Receive Tool; Assigned to Arm(s): Immediately Receive Tool | Intervention Type: BEHAVIORAL; Name: One Month Delay; Assigned to Arm(s): One Month Delay
B: Arm Label: Behavioral Activation; Type: EXPERIMENTAL; Interventions: Behavioral: Behavioral activation, Other: Psychoeducation | Arm Label: Psychoeducation; Type: ACTIVE_COMPARATOR; Interventions: Other: Psychoeducation | Intervention Type: BEHAVIORAL; Name: Behavioral activation; Assigned to Arm(s): Behavioral Activation | Intervention Type: OTHER; Name: Psychoeducation; Assigned to Arm(s): Behavioral Activation, Psychoeducation
C: Arm Label: intervention; Type: EXPERIMENTAL; Interventions: Other: structured support groups | Arm Label: control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: structured support groups; Assigned to Arm(s): intervention
D: Arm Label: Care Notebook; Type: OTHER; Interventions: Behavioral: Care Notebook | Arm Label: Care Notebook + Parent Navigator; Type: EXPERIMENTAL; Interventions: Behavioral: Parent Navigator, Behavioral: Care Notebook | Intervention Type: BEHAVIORAL; Name: Parent Navigator; Assigned to Arm(s): Care Notebook + Parent Navigator | Intervention Type: BEHAVIORAL; Name: Care Notebook; Assigned to Arm(s): Care Notebook, Care Notebook + Parent Navigator

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: An Innovative Caregiver Tool to Assess and Manage Behavioral Symptoms of Dementia
Brief Summary: Behavioral symptoms that commonly occur with dementia are associated with increased health care utilization and can lead to challenges for the person living with dementia and their caregivers. Caregivers need knowledge and skills to monitor these behaviors, to identify what triggers them, and to learn how to use proven, practical medication-free strategies to prevent and manage the behaviors. The purpose of this study is to develop and test the WeCareAdvisor, a customized, internet-based computer tool for family caregivers that helps them to assess, manage and track behavioral symptoms and their contributing factors (e.g., pain, sleep disturbance), and that provides tailored strategies for in-home, medication-free behavior management. This study is a collaboration between researchers at the University of Michigan and Johns Hopkins University.


Options:
A: Arm Label: Immediately Receive Tool; Type: EXPERIMENTAL; Interventions: Behavioral: Immediately Receive Tool | Arm Label: One Month Delay; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: One Month Delay | Intervention Type: BEHAVIORAL; Name: Immediately Receive Tool; Assigned to Arm(s): Immediately Receive Tool | Intervention Type: BEHAVIORAL; Name: One Month Delay; Assigned to Arm(s): One Month Delay
B: Arm Label: Behavioral Activation; Type: EXPERIMENTAL; Interventions: Behavioral: Behavioral activation, Other: Psychoeducation | Arm Label: Psychoeducation; Type: ACTIVE_COMPARATOR; Interventions: Other: Psychoeducation | Intervention Type: BEHAVIORAL; Name: Behavioral activation; Assigned to Arm(s): Behavioral Activation | Intervention Type: OTHER; Name: Psychoeducation; Assigned to Arm(s): Behavioral Activation, Psychoeducation
C: Arm Label: positive affect intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Positive Affect | Arm Label: wait list control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Positive Affect; Assigned to Arm(s): positive affect intervention
D: Arm Label: Usual Care; Type: ACTIVE_COMPARATOR; Interventions: Other: light support, Other: 3 preventive home visits by a nurse | Arm Label: UP Protocol; Type: EXPERIMENTAL; Interventions: Other: Case Manager, Other: 3 preventive home visits by a nurse | Arm Label: UP-TECH Protocol; Type: EXPERIMENTAL; Interventions: Other: Case Manager, Other: Assistive Technologies, Other: 3 preventive home visits by a nurse | Intervention Type: OTHER; Name: Case Manager; Assigned to Arm(s): UP Protocol, UP-TECH Protocol | Intervention Type: OTHER; Name: Assistive Technologies; Assigned to Arm(s): UP-TECH Protocol | Intervention Type: OTHER; Name: light support; Assigned to Arm(s): Usual Care | Intervention Type: OTHER; Name: 3 preventive home visits by a nurse; Assigned to Arm(s): UP Protocol, UP-TECH Protocol, Usual Care

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase III, Open-Label, Randomized Study of Atezolizumab (Anti-PD-L1 Antibody) in Combination With Bevacizumab Versus Sunitinib in Patients With Untreated Advanced Renal Cell Carcinoma
Brief Summary: This multi-center, randomized, open-label study will evaluate the efficacy and safety of atezolizumab plus bevacizumab versus sunitinib in participants with inoperable, locally advanced, or metastatic RCC who have not received prior systemic active or experimental therapy, either in the adjuvant or metastatic setting.


Options:
A: Arm Label: Atezolizumab + Bevacizumab; Type: EXPERIMENTAL; Interventions: Drug: Atezolizumab (MPDL3280A), an engineered anti-PD-L1 antibody, Drug: Bevacizumab | Arm Label: Sunitinib; Type: ACTIVE_COMPARATOR; Interventions: Drug: Sunitinib | Intervention Type: DRUG; Name: Atezolizumab (MPDL3280A), an engineered anti-PD-L1 antibody; Assigned to Arm(s): Atezolizumab + Bevacizumab | Intervention Type: DRUG; Name: Bevacizumab; Assigned to Arm(s): Atezolizumab + Bevacizumab | Intervention Type: DRUG; Name: Sunitinib; Assigned to Arm(s): Sunitinib
B: Arm Label: A; Type: OTHER; Interventions: Drug: axitinib | Arm Label: B; Type: OTHER; Interventions: Drug: axitinib | Arm Label: C; Type: OTHER; Interventions: Drug: axitinib | Intervention Type: DRUG; Name: axitinib; Assigned to Arm(s): A | Intervention Type: DRUG; Name: axitinib; Assigned to Arm(s): B | Intervention Type: DRUG; Name: axitinib; Assigned to Arm(s): C
C: Arm Label: LY2510924 + Sunitinib; Type: EXPERIMENTAL; Interventions: Drug: LY2510924, Drug: Sunitinib | Arm Label: Sunitinib; Type: ACTIVE_COMPARATOR; Interventions: Drug: Sunitinib | Intervention Type: DRUG; Name: LY2510924; Assigned to Arm(s): LY2510924 + Sunitinib | Intervention Type: DRUG; Name: Sunitinib; Assigned to Arm(s): LY2510924 + Sunitinib, Sunitinib
D: Arm Label: A; Type: EXPERIMENTAL; Interventions: Drug: Axitinib (AG-013736) | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Drug: Sorafenib | Intervention Type: DRUG; Name: Axitinib (AG-013736); Assigned to Arm(s): A | Intervention Type: DRUG; Name: Sorafenib; Assigned to Arm(s): B

Answer: A