Please select the eligibility criteria that correspond to the clinical trial below.
Title: Subacute Stroke Recovery (Upper Extremity Motor Function): Bimanual Coordination Training
Brief Summary: The purpose of this study was to determine the effect of two amounts of treatment therapy on post stroke motor recovery in the arms. The therapy is bilateral movement training combined with electrical stimulation on the impaired limb.


Options:
A: Inclusion Criteria:

* first major unilateral hemispheric stroke,
* english speaking,
* adequate verbal communication,
* discharged home or residential care

Exclusion Criteria:

* serious comorbidities (eg. cancer, mobility limiting arthritis, leg amputation)
B: Inclusion Criteria:

* Between the ages of 40 - 85
* Had a stroke at least 12 months ago
* OR are a healthy adult who does not have a history of neurodegenerative disorders
* Have the ability to understand English

Exclusion Criteria:

* Contraindication to brain stimulation (such as a history of seizure or epilepsy)
* Contraindication to MRI (such as a pacemaker, metal in the eyes / brain or fear of enclosed spaces)
* Neurodegenerative disorder ( such as Parkinson disease, Alzheimers disease or Multiple Sclerosis)
* Contraindications to exercise
C: Inclusion Criteria:

* age between 18 and 86
* patient is contractually capable
* first-ever, ischemic stroke
* minimum time since stroke 9 months
* a paresis of the arm/hand muscles above 3 on the MRC scale

Exclusion Criteria:

* multiple cerebral lesions and associated residual deficits
* severe head trauma in the past
* seizures
* ferromagnetic implants in the head/neck region
* pacemaker
* a psychiatric disorder or neurological disease besides stroke
* intake of illegal drugs
* severe aphasia or cognitive deficits that impede contractual capability
* contraindications for reboxetine (seizures, glaucoma, prostate hyperplasia with urinary retention, cardiac arrhythmias, potential interactions with co-medication)
* pregnancy
* breast-feeding patients
D: Inclusion Criteria:

* an ability to complete 10º of wrist or finger extension from a 60 - 65 º flexed position
* score less than a 56 on the UE subscale of the Fugl-Meyer Assessment
* an ability to voluntarily activate slight movements in the wrist and fingers so that the EMG activity reaches a minimal level on the microprocessor for electrical stimulation to be activated
* unilateral, first stroke of ischemic or hemorrhagic origin in the carotid artery distribution
* free of major post stroke complications
* able to attend therapy 2 days/week or 4 days/week for 2 weeks
* score at least a 16 on the Mini Mental Status Examination
* able to discriminate sharp from dull and light touch using traditional sensation tests.

Exclusion Criteria:

* hemiparetic arm is insensate
* motor impairments from stroke on opposite side of body
* pre-existing neurological disorders such as Parkinson's disease, Multiple Sclerosis, or dementia
* Legal blindness or severe visual impairment; 5) Life expectancy less than one year
* Severe arthritis or orthopedic problems that limit passive ranges of motion of upper extremity (passive finger extension \< 40º; passive wrist extension \< 40º; passive elbow extension \<40º; shoulder flexion/abduction \< 80º)
* History of sustained alcoholism or drug abuse in the last six months
* Has pacemaker or other implanted device
* pregnant

Answer: D