Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Biobehavioral Bases & Management of Metabolic Syndrome
Brief Summary: The metabolic syndrome is increasingly being recognized as a major threat to good health - especially cardiovascular health - and its frequency appears to be increasing in relation to the current epidemic of obesity. The objective of this study is to determine whether a program of enhanced lifestyle intervention can, compared to standard care, reduce the frequency and severity of the metabolic syndrome as assessed by clinical, metabolic, inflammatory and vascular outcome measures. EC will consist of a 17-session structured, lifestyle intervention plan, directed at achieving weight reduction and increasing physical activity change through education, behavior modification and stress management, and conducted in groups. It will comprise a 3-month Core Curriculum of 8 sessions, followed by a Maintenance phase with 9 monthly sessions delivered by lifestyle counselors, experienced in breaking through barriers in working with socioeconomically disadvantaged members of minority groups. All participants will have baseline, 6-monthly and 1-year assessments. This project, Project 2, entitled Community Health Approaches to Reducing Risk in the Metabolic Syndrome (CHARMS), seeks to study psychosocial and behavioral (lifestyle) variables that may contribute to the progression or amelioration of atherosclerotic processes underlying the pathogenesis of coronary heart disease (CHD).


Options:
A: Arm Label: Liraglutide 3.0mg (week0-56)/Liraglutide 3.0mg (week56-68); Type: EXPERIMENTAL; Interventions: Drug: liraglutide | Arm Label: Liraglutide 3.0mg (week0-56)/Liraglutide Placebo (week56-68); Type: EXPERIMENTAL; Interventions: Drug: placebo | Arm Label: Liraglutide Placebo, no Pre-diabetes; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Arm Label: Liraglutide 3.0mg, Pre-diabetes; Type: EXPERIMENTAL; Interventions: Drug: liraglutide | Arm Label: Liraglutide Placebo, Pre-diabetes; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Intervention Type: DRUG; Name: liraglutide; Assigned to Arm(s): Liraglutide 3.0mg (week0-56)/Liraglutide 3.0mg (week56-68) | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Liraglutide 3.0mg (week0-56)/Liraglutide Placebo (week56-68), Liraglutide Placebo, no Pre-diabetes | Intervention Type: DRUG; Name: liraglutide; Assigned to Arm(s): Liraglutide 3.0mg, Pre-diabetes | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Liraglutide Placebo, Pre-diabetes
B: Arm Label: Intermittent Calorie Restriction; Type: EXPERIMENTAL; Interventions: Other: Calorie Restriction | Arm Label: Continuous Calorie Restriction; Type: EXPERIMENTAL; Interventions: Other: Calorie Restriction | Arm Label: Healthy Nutrition; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Calorie Restriction; Assigned to Arm(s): Continuous Calorie Restriction, Intermittent Calorie Restriction
C: Arm Label: Daily energy restriction; Type: EXPERIMENTAL; Interventions: Other: Energy restriction | Arm Label: Energy balance diet; Type: ACTIVE_COMPARATOR; Interventions: Other: Energy balance diet | Arm Label: Periodic fasting with weight loss; Type: EXPERIMENTAL; Interventions: Other: Periodic fasting, Other: Energy restriction | Arm Label: Periodic fasting without weight loss; Type: EXPERIMENTAL; Interventions: Other: Periodic fasting, Other: Energy balance diet | Intervention Type: OTHER; Name: Periodic fasting; Assigned to Arm(s): Periodic fasting with weight loss, Periodic fasting without weight loss | Intervention Type: OTHER; Name: Energy restriction; Assigned to Arm(s): Daily energy restriction, Periodic fasting with weight loss | Intervention Type: OTHER; Name: Energy balance diet; Assigned to Arm(s): Energy balance diet, Periodic fasting without weight loss
D: Arm Label: Lifestyle counseling; Type: EXPERIMENTAL; Interventions: Behavioral: CHARMS | Intervention Type: BEHAVIORAL; Name: CHARMS; Assigned to Arm(s): Lifestyle counseling

Answer: D