TrialPanorama/Dataset huggingface dataset:
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Feasibility Study of the PneumRx, Inc. Lung Volume Reduction Coil for the Treatment of Emphysema
Brief Summary: This is a multicenter single arm open label study. The primary objective is to evaluate the safety and effectiveness of the Lung Volume Reduction Coil (LVRC) for the treatment of patients with emphysema in multiple centers.


Options:
A: Inclusion Criteria:

* age \> 40 inhomogeneous emphysema FEV1 between 20-40% DLCO between 20-40% 6MWT \> 150 m

Exclusion Criteria:

* pregnant homogeneous disease FEV1 \< 20%
B: Inclusion Criteria:

* Greater than or equal to 35 years of age
* bilateral heterogenous emphysema
* Patient has stopped smoking for a minimum of 8 weeks
* Read, understood and signed the Informed consent form

Exclusion Criteria:

* Patient has a history of recurrent significant respirator infection
* Patient has an inability to walk \> 140 meters
* Patient has evidence of other disease that may compromise survival such as lung cancer, renal failure, etc
* Patient is pregnant or lactating
* Patient has clinical significant bronchiectasis
* Patient has had previous LVR surgery, lung transplant or lobectomy
* Patient has been involved in other pulmonary drug studies within 30 days prior to this study
C: Inclusion Criteria:

* Between 40 and 74 years of age
* Predominantly upper lobe emphysema and severe dyspnea
* Satisfies the criteria of the ATS/ERS Guidelines for Management of Stable COPD
* Physical ability to participate in the study by performing a 6-minute walk distance of \> 140m
* No cigarette smoking for 4 months and willing to abstain throughout the study
* Severe airflow obstruction defined by FEV1 45% of predicted
* Severe hyperinflation defined by: TLC \> 100% of predicted and RV \> 150% of predicted

Exclusion Criteria:

* Between 70 and 74 years of age and an FEV1 or DLCO \< 20% of predicted
* Severe gas exchange abnormalities
* Major medical disease that will limit evaluation, participation or follow-up
* Active asthma component to their disease
* Giant bulla (\> 1/3 volume of lung)
* Severe pulmonary hypertension
* Requirement for \> 6L02 to keep saturation \> 90% with exercise
* Evidence of systemic disease or neoplasia expected to compromise survival during the 6-month study period
D: Inclusion Criteria:

* Candidates have mostly upper lobe, severe emphysema.
* Must be able to participate in standard exercise testing.
* Willing to abstain from cigarette smoking for 4 months prior and during the entire trial.
* Willing to participate in a randomized, blinded study and complete the required follow-up visits during the study period.
* Willing to participate in multiple visits to a medical center for health assessment tests.
* Willing to have a minimum of one overnight stay in the hospital.

Exclusion Criteria:

* Evidence of another co-existing major medical disease.
* Unable to tolerate, flexible bronchoscopy procedures.
* Active asthma, chronic bronchitis.
* Diffuse emphysema pattern, alpha 1-antitrypsin deficiency.
* Has had prior lung volume reduction surgery.

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Tailored Youth Drug Intervention In Primary Care
Brief Summary: This study examines the impact of tailored computer-delivered and therapist-delivered brief motivations prevention/interventions both for adolescents who have not initiated marijuana use (prevention), and those who use marijuana (intervention). Key moderators of prevention/intervention effectiveness will be examined, including behavioral intentions, self-efficacy, stage of change, school involvement, susceptibility to peer pressure, and potential health consequences such as STD/HIV risk behaviors. This project will provide the critical first step toward the development and implementation of marijuana use prevention/intervention programs that have the potential to be delivered to a large segment of youth who seek care in our nation's primary care settings.


Options:
A: Inclusion Criteria:

* Child aged 13-17 years
* Receiving treatment at the approved medical Emergency Department
* Child living in a home with at least one parent or legal guardian

Exclusion Criteria:

* Children who are suicidal, in police custody, not alert/oriented, non-English speaking, in severe pain, or who have sustained severe trauma
* Children with a history of prior substance abuse treatment
B: Inclusion Criteria:

* All young people between the ages of 14 and 17 who were in the detention centers at which recruitment took place.

Exclusion Criteria:

* Age less than 14 or non-English speaking
C: Inclusion Criteria:

* adolescents (ages 12-18) presenting to the approved health clinics (except exclusions as noted below)
* ability to provide informed assent
* access to a parent or guardian for parental consent

Exclusion Criteria:

* adolescents who do not understand English
* adolescents deemed unable to provide informed consent by research staff (e.g., cognitive issues)
* adolescents who come to the clinic because of sexual assault or suicide attempt, or are presenting with high psychological distress requiring intensive attention
* prisoners
* adolescents who are deaf
* adolescents with a sibling or other household member in the study will be excluded from Phase II
D: Inclusion Criteria:

* adolescents (ages 14-18) presenting to the ED for a medical injury or illness (except exclusions as noted below)
* adolescents ability to provide informed assent/consent depending on age
* access to a parent or guardian to provide informed consent

Exclusion Criteria:

* adolescents who do not understand English
* prisoners
* adolescents classified by medical staff as "Level 1" trauma
* adolescents deemed unable to provide informed consent
* adolescents treated in the ED for suicide attempts
* adolescents triaged to the psychiatric ED

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: An Evaluation of Hydrocodone/Acetaminophen for Pain Control in First Trimester Surgical Abortion
Brief Summary: The purpose of this study is to determine whether preoperatively administered hydrocodone/acetaminophen (HC/APAP) reduces pain during a first trimester surgical abortion.


Options:
A: Inclusion Criteria:

* 18 years old or older,
* elective pregnancy termination at gestational age of less than 11 weeks,
* speak English
* candidate for an in-clinic procedure.
* desire local anesthesia, ibuprofen, Vicodin and Ativan (the usual treatment in our clinic) for managing pain

Exclusion Criteria:

* no medical problems preventing the use of nitrous oxide
* no allergies to nitrous oxide, lidocaine, vasopressin, ibuprofen, Vicodin or Ativan
* significant active upper respiratory infection
* chronic obstructive pulmonary disease (COPD)
* intoxication
* use of street drugs
B: Inclusion Criteria:

* Aged 18 years or older
* Voluntarily requesting surgical pregnancy termination
* Pregnancy with intrauterine gestational sac up to 10 weeks 6 days gestation, dated by ultrasound
* Eligible for suction curettage
* English or Spanish speaking
* Good general health
* Able and willing to give informed consent and agree to terms of the study

Exclusion Criteria:

* Gestational ages 11 weeks or more
* Incomplete abortion
* Premedication with misoprostol
* Use of any opioid medication within the past 7 days
* Use of heroin within the past 7 days
* Requested opioids or IV sedation prior to start of the procedure
* Patients who refuse ibuprofen or lorazepam
* Contraindications or allergies to HC/APAP, lidocaine, ibuprofen, or lorazepam
* Significant medical problem necessitating inpatient procedure
* Adnexal mass or tenderness on pelvic exam consistent with pelvic inflammatory disease
* Known hepatic disease
C: Inclusion Criteria:

* Women \>=18 years-old
* Presenting for a surgical abortion
* Fluency in English and able to provide informed consent
* Has a driver to take them home following the procedure

Exclusion Criteria:

* Allergy, sensitivity or contraindication to gabapentin
* Severe renal disease
* Currently using gabapentin or pregabalin
* Contraindication to outpatient abortion under local anesthesia
D: Inclusion Criteria:

* Women \>=18 years-old
* Presenting for a surgical abortion
* No contraindication to outpatient abortion
* No contraindication to gabapentin
* Fluency in English and able to provide informed consent

Exclusion Criteria:

* Allergy, sensitivity or contraindication to gabapentin
* Severe renal disease
* Currently using gabapentin or pregalabin

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Community-Based Lifestyle Promotion With Latino Women
Brief Summary: The overall goal of this randomized controlled trial is to evaluate the effects of a community-based lifestyle behavior intervention (LSBI) that is designed to improve dietary habits and physical activity (PA), and reduce weight of Latino women who are predominantly Spanish-speaking immigrants. It is hypothesized that middle-aged overweight/obese Latinas participating in a LSBI conducted by lay health advisors will demonstrate improved dietary habits, increased physical activity and a decrease in BMI compared to those in a control condition, Women in the LSBI also are expected to demonstrate improvements in selected physiologic outcomes (waist circumference, blood pressure \[BP\], measures of cholesterol and blood sugar).


Options:
A: Inclusion Criteria:

* Latina
* 35 to 64 years of age
* body mass index (BMI) \>25
* fluent in either Spanish or English.

Exclusion Criteria:

* pregnant or planning to get pregnant in next year
* history of myocardial infarction or stroke
* currently under treatment for cancer
* orthopedic or joint problems that would prohibit participation in physical activity
* insulin-dependent diabetes
B: Inclusion Criteria:

* Aged 18 -60
* BMI between 20 -38
* Willing to attend 10 weekly education sessions
* Able to speak and understand Spanish
* Have medical insurance

Exclusion Criteria:

* Fasting blood glucose about 126mg/dL unless physician attests fit to participate
* Pregnancy or trying to conceive, or breastfeeding
* Diabetic
* On therapeutic diets
* On medications that affect weight
* If spouse / cohabitant already in the study
* Not a farm worker working for the Reiter Affiliated Companies
C: Inclusion Criteria:

* At high risk for impending death in the next 12 months

Exclusion Criteria:

* Patient not having decision-making capacity
D: Inclusion Criteria:

* Subjects with a history of kidney transplantation within the last 5 years
* Speaks English
* Can see to read
* Lives in the greater Chicago area and can attend a cognitive interview session
* 18-85 years old

Exclusion Criteria:

* Unable to speak English
* Cognitive impairment or neurologic disease
* Dementia or insufficient cognitive skills to follow instructions provided at a sixth grade language level
* Has had a skin cancer

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Does Schooling Protect Young Women From HIV?
Brief Summary: This study is designed to evaluate a two-year randomized intervention in Malawi that provides cash transfers to current schoolgirls (and young women who have recently dropped out of school) to stay in (and return to) school in order to understand the possible effects of such programs on the sexual behavior of the beneficiaries and their subsequent HIV risk.


Options:
A: Inclusion Criteria:

* Households with residential or mailing address in Hampden County, Massachusetts
* Receiving SNAP benefits in July 2011

Exclusion Criteria:

* Child-only cases (households not including at least one member aged 16 or older eligible to serve as SNAP head of household)
* Cases with benefits signed over to residential or treatment facilities
B: Inclusion Criteria:

* Mother of child between the ages of 3 and 12 months and her child

Exclusion Criteria:

* N/A
C: Inclusion Criteria:

-All households with children under 5 years in the study communities are eligible for socio-economic and health outcome evaluation.

Exclusion Criteria:

-All households are eligible to participate in the intervention. However, for the purposes of the study, households with no children under the age of 5 will not be selected for data collection purposes.
D: Inclusion Criteria:

* female
* 13-22 years old
* never married

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Does Schooling Protect Young Women From HIV?
Brief Summary: This study is designed to evaluate a two-year randomized intervention in Malawi that provides cash transfers to current schoolgirls (and young women who have recently dropped out of school) to stay in (and return to) school in order to understand the possible effects of such programs on the sexual behavior of the beneficiaries and their subsequent HIV risk.


Options:
A: Inclusion Criteria:

* Live in a community that does not receive benefits from other federal food aid programs, have less than 2,500 inhabitants and a high level of marginalization. Marginalization is a term used in Mexico for the multidimensional assessment of poverty in a community. It takes into account housing quality (including the percent of households without piped water, without sewage and without electricity), income (proportion of household below two times the minimum wage), education (including illiteracy) and urbanization.
* Households within these communities were eligible if they fell below the "needs" poverty line as defined by the Mexican Ministry of Social Development. This corresponds to an income level sufficient to cover basic needs in food consumption, health and education.
B: Inclusion Criteria:

* Poor or very poor household (HEA criteria)
* Having at least one children under 1 year old at the time of inclusion

Exclusion Criteria:

* Medium or rich economic status (HEA criteria)
* no child under one year old at the time of inclusion
* not living in one of the 32 selected villages in the Tapoa province
C: Inclusion Criteria:

* female
* 13-22 years old
* never married
D: Inclusion Criteria:

* Living in the catchment area of one of the 20 outpatient therapeutic program site participating in this cluster randomized trial;
* 6-59 months of age;
* Weight for Height Zscore \<-3 SD (WHO Growth Standards 2006) and/or Mid-Upper Arm Circumference \<115mm and/or with bilateral edema;
* No major clinical complications;
* Positive appetite test;
* Accept to participate at the study.

Exclusion Criteria:

* Not living in the catchment area of the outpatient therapeutic program site of the cluster randomized trial;
* Weight-for-Height Z-score ≥-3 (WHO Growth Standards 2006) and Mid-Upper Arm Circumference ≥115mm without bilateral edema;
* Major clinical complications;
* Failure to appetite test;
* Refuse to participate at the study.

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Does Schooling Protect Young Women From HIV?
Brief Summary: This study is designed to evaluate a two-year randomized intervention in Malawi that provides cash transfers to current schoolgirls (and young women who have recently dropped out of school) to stay in (and return to) school in order to understand the possible effects of such programs on the sexual behavior of the beneficiaries and their subsequent HIV risk.


Options:
A: Inclusion Criteria:

A household will be defined as vulnerable and thereby eligible for inclusion in the programme if there are children \<18 years resident in the household at baseline AND

* household is in the poorest quintile of households (20%) at baseline OR
* household contains one or more orphans at baseline OR
* the household head is under 18 years of age at baseline OR
* household contains a chronically ill member OR
* household contains a disabled member

A household will be defined as individuals that live within the same homestead and eat from the same pot.

Exclusion Criteria:

Households already receiving cash transfers for orphans or vulnerable children (OVC) will not be eligible to enroll in the pilot programme.

During the trial, households that do not qualify at baseline but whose conditions later change such that they become eligible to participate in the pilot will not be able to enroll.
B: Inclusion Criteria:

* Households in pre-selected neighborhoods in Carchi and Sucumbios with high poverty status according to the proxy means test.
* For hemoglobin measurements, children residing in these households that are 6 months-5 years old, and adolescent girls 10-16 years old

Exclusion Criteria:

* Households that receive the Bono de Desarrollo Humano
* Children ages 6 months - 5 years who are severely sick
C: Inclusion Criteria:

* Living in the catchment area of one of the 20 outpatient therapeutic program site participating in this cluster randomized trial;
* 6-59 months of age;
* Weight for Height Zscore \<-3 SD (WHO Growth Standards 2006) and/or Mid-Upper Arm Circumference \<115mm and/or with bilateral edema;
* No major clinical complications;
* Positive appetite test;
* Accept to participate at the study.

Exclusion Criteria:

* Not living in the catchment area of the outpatient therapeutic program site of the cluster randomized trial;
* Weight-for-Height Z-score ≥-3 (WHO Growth Standards 2006) and Mid-Upper Arm Circumference ≥115mm without bilateral edema;
* Major clinical complications;
* Failure to appetite test;
* Refuse to participate at the study.
D: Inclusion Criteria:

* female
* 13-22 years old
* never married

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Does Schooling Protect Young Women From HIV?
Brief Summary: This study is designed to evaluate a two-year randomized intervention in Malawi that provides cash transfers to current schoolgirls (and young women who have recently dropped out of school) to stay in (and return to) school in order to understand the possible effects of such programs on the sexual behavior of the beneficiaries and their subsequent HIV risk.


Options:
A: Inclusion Criteria:

* female
* 13-22 years old
* never married
B: Inclusion Criteria:

A household will be defined as vulnerable and thereby eligible for inclusion in the programme if there are children \<18 years resident in the household at baseline AND

* household is in the poorest quintile of households (20%) at baseline OR
* household contains one or more orphans at baseline OR
* the household head is under 18 years of age at baseline OR
* household contains a chronically ill member OR
* household contains a disabled member

A household will be defined as individuals that live within the same homestead and eat from the same pot.

Exclusion Criteria:

Households already receiving cash transfers for orphans or vulnerable children (OVC) will not be eligible to enroll in the pilot programme.

During the trial, households that do not qualify at baseline but whose conditions later change such that they become eligible to participate in the pilot will not be able to enroll.
C: Inclusion Criteria:

* Households in pre-selected neighborhoods in Carchi and Sucumbios with high poverty status according to the proxy means test.
* For hemoglobin measurements, children residing in these households that are 6 months-5 years old, and adolescent girls 10-16 years old

Exclusion Criteria:

* Households that receive the Bono de Desarrollo Humano
* Children ages 6 months - 5 years who are severely sick
D: Inclusion Criteria:

* Living in the catchment area of one of the 20 outpatient therapeutic program site participating in this cluster randomized trial;
* 6-59 months of age;
* Weight for Height Zscore \<-3 SD (WHO Growth Standards 2006) and/or Mid-Upper Arm Circumference \<115mm and/or with bilateral edema;
* No major clinical complications;
* Positive appetite test;
* Accept to participate at the study.

Exclusion Criteria:

* Not living in the catchment area of the outpatient therapeutic program site of the cluster randomized trial;
* Weight-for-Height Z-score ≥-3 (WHO Growth Standards 2006) and Mid-Upper Arm Circumference ≥115mm without bilateral edema;
* Major clinical complications;
* Failure to appetite test;
* Refuse to participate at the study.

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Does Schooling Protect Young Women From HIV?
Brief Summary: This study is designed to evaluate a two-year randomized intervention in Malawi that provides cash transfers to current schoolgirls (and young women who have recently dropped out of school) to stay in (and return to) school in order to understand the possible effects of such programs on the sexual behavior of the beneficiaries and their subsequent HIV risk.


Options:
A: Inclusion Criteria:

* female
* 13-22 years old
* never married
B: Inclusion Criteria:

* Grade 6 or 7 student at a participating school
* Written parent or guardian consent to participate
* Self-identifies as African American or black

Exclusion Criteria:

- Those not meeting inclusion criteria were excluded.
C: Inclusion Criteria:

* Enrolled in collaborating adolescent substance abuse treatment program (i.e., Daytop's Brooklyn Outreach Center, Bronx Outreach Center or Queens Outreach Center)
* 12-18 years of age
* Within first 30 days of substance abuse treatment (current treatment episode)
* Not yet received formal HIV prevention intervention during current treatment episode

Exclusion Criteria:

* Plans to move out of the area within the next 5 months
* Insufficient ability to understand and provide informed consent/assent to participate
* Insufficient ability to use English to participate in the consent process, the interventions and/or assessments
D: Inclusion Criteria:

* Adolescent girls in Standard 7

Exclusion Criteria:

* None

Answer: A