Please select the eligibility criteria that correspond to the clinical trial below.
Title: Closing Linear Incisions in Plastic Surgery: A Randomized Clinical Trial Comparing a New Coaptive Film Device Versus Standard Subcuticular Sutures for Scar Quality, Patient Comfort, and Closure Time
Brief Summary: Purpose: The aims of this randomized clinical trial are:

1. to assess scar quality from the patient and surgeon perspectives
2. to assess patient comfort in the days immediately following surgery
3. to assess the time taken to complete closure in the operating room.
4. the financial benefit or cost for the institution of using Steri Strip S will also be estimated.

Two closure methods will be compared, a new coaptive film device (Steri Strip S) versus standard subcuticular sutures. The linear incisions will include the standard incision segments utilized for an inverted-T closure for bilateral breast reduction and the transabdominal incision segments utilized for abdominoplasty or TRAM flap harvest.

Our hypothesis is that incisions segments closed with Steri Strip S compared to standard subcuticular closure, will yield scars of better cosmetic quality, in shorter time to closure, with novice and expert surgeons, for both bilateral breast reduction and abdominoplasty surgical procedures.


Options:
A: Inclusion Criteria:

* Both gender
* Appendicitis diagnosis
* Informed consent signed
* 0-60 age year old
* surgical confirmation of acute appendicitis
* Antibiotic prophylaxis

Exclusion Criteria:

* Appendicitis diagnosis in patients \>60 years old
* No antibiotic prophylaxis
* No informed consent signed
B: Inclusion Criteria:

* All women, \>=18 and \<= 85 years of age, undergoing surgery, via a midline laparotomy.
* Body mass index \>=30
* Benign or oncologic indications for surgery.
* Women of childbearing age will be required to have a negative human chorionic gonadotropin (HCG) test within seven days of surgery.
* Surgery will be supervised by one of the gynecologic oncology attendings at Washington University School of Medicine.
* Ability to understand and willingness to sign an IRB approved written informed consent document.

Exclusion Criteria:

* Women who are pregnant or breastfeeding
* Pfannenstiel or transverse abdominal incision
* Concomitant panniculectomy or plastic surgery
* Women \<18 years of age
* History of prior abdominal or pelvic radiation
* Inability to sign an informed consent form prior to registration on study
* Inability to understand spoken or written English
* Prisoner
* Mental incapacity
* A history of allergic reactions attributed to either Monocryl suture or stainless steel staples.
C: Inclusion Criteria:

* 18 years of age or older with written informed consent
* Scheduled for a modified radical mastectomy
* Surgical wound classified Class I/Clean using the CDC SSI Surgical Wound Classification

Exclusion Criteria:

* Unable to give consent and unlikely to comply with study requirements and complete the 90-day follow up visit
* Undergoing surgery for modified radical mastectomy with immediate breast reconstruction, cosmetic breast operations, reduction, expansion, insertion of prothesis, duct ectasia or infective breast disease or implant
* Surgical wounds classified as Class II, III or IV using CDC SSI Surgical Wound Classification
* Has inflammatory cancers or skin ulceration
* Has known allergy or intolerance to triclosan
* Has compromised wound healing or chronic immune deficiency, for example diabetes, prolonged steroid use, AIDS or substance abuse
* Has serious heart and/or lung disease
* Has skin scar history or family history
* Has direct relationship to or involvement in this or other studies under the direction of the investigator or center
* Received an experimental drug or device within 30 days prior to the planned start of treatment
D: Inclusion Criteria:

* Patients are eligible for enrollment if they agree to provide informed consent, are at least 18 years of age, in generally good health, and available for follow-up in the 5-7 month time frame.

Exclusion Criteria:

* Women known to be pregnant, minors, patients potentially incompetent to provide informed consent or complete the surveys described in our protocol will be excluded from this trial.

Answer: D