Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Prospective, Controlled, Randomized Study of Intraoperative Colonic Irrigation vs. Stent Placement in Obstructive Left-Sided Colonic Cancer
Brief Summary: INTRODUCTION: There are several alternatives for one-stage emergency treatment of obstructive left-sided colonic cancer (OLCC): subtotal colectomy, intraoperative colon lavage (IOCL) with primary anastomosis, and the placement of a stent as a temporary measure prior to scheduled surgery. At present, it is not clear whether emergency perioperative lavage or the placement of a stent is the better technique. The hypothesis is that IOCL and primary anastomosis is equal safe or even safer than placement of a stent as a temporary measure prior to scheduled surgery, less length of stay and less cost.

OBJECTIVE: To establish which of these two techniques is more efficient in OLCC from the point of view of morbimortality, economic cost, and long-term survival.

MATERIAL AND METHODS:

Prospective, controlled, randomized study of patients diagnosed with OLCC. Patients were divided into two groups: group 1: stent and deferred surgery; group 2: emergency IOCL. A simple randomization system was used. The estimated sample size required per group was 21 patients. Demographic variables, risk prediction models, postoperative morbimortality, staging, complications due to the placement of stent, surgical time, clinical follow-up, health costs and follow-up of survival were recorded.


Options:
A: Arm Label: intraoperative colon lavage; Type: EXPERIMENTAL; Interventions: Procedure: intraoperative colon lavage with primary anastomosis | Arm Label: stent and deferred surgery; Type: ACTIVE_COMPARATOR; Interventions: Procedure: intraoperative colon lavage with primary anastomosis | Intervention Type: PROCEDURE; Name: intraoperative colon lavage with primary anastomosis; Assigned to Arm(s): intraoperative colon lavage, stent and deferred surgery
B: Arm Label: Irrigation; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Normal Saline Irrigation | Arm Label: No Irrigation; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: PROCEDURE; Name: Normal Saline Irrigation; Assigned to Arm(s): Irrigation
C: Arm Label: local instillation of morphine 5 mg; Type: ACTIVE_COMPARATOR; Interventions: Drug: local instillation of morphine to surgical wound | Arm Label: local instillation of morphine 10 mg; Type: ACTIVE_COMPARATOR; Interventions: Drug: local instillation of morphine to surgical wound | Arm Label: local instillation of morphine 15 mg; Type: ACTIVE_COMPARATOR; Interventions: Drug: local instillation of morphine to surgical wound | Arm Label: local instillation of local anesthetics; Type: PLACEBO_COMPARATOR; Interventions: Drug: local instillation of morphine to surgical wound | Intervention Type: DRUG; Name: local instillation of morphine to surgical wound; Assigned to Arm(s): local instillation of local anesthetics, local instillation of morphine 10 mg, local instillation of morphine 15 mg, local instillation of morphine 5 mg
D: Arm Label: SILS; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Single Incision Laparoscopic Appendectomy | Arm Label: 3 port; Type: ACTIVE_COMPARATOR; Interventions: Procedure: 3 port laparoscopic appendectomy | Intervention Type: PROCEDURE; Name: Single Incision Laparoscopic Appendectomy; Assigned to Arm(s): SILS | Intervention Type: PROCEDURE; Name: 3 port laparoscopic appendectomy; Assigned to Arm(s): 3 port

Answer: A