TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomised Controlled Trial of a Fixed-dose Combination Polypill Medication (the Red Heart Pill) and Usual Care in Those at High Risk of Cardiovascular Disease.
Brief Summary: People with established cardiovascular disease need secondary prevention that addresses multiple risk factors. Complexity \& cost confer particularly difficult barriers to uptake of treatment; recovery from a stroke or heart attack typically necessitates multiple drugs for cholesterol, blood pressure and platelet function. A low-cost, fixed-dose, once-daily combination polypill, the Red Heart Pill, has been formulated by Dr Reddy's Laboratories. UMPIRE will evaluate whether provision of this polypill compared with usual medications improves adherence and clinical outcomes among high-risk patients in Europe and India. The results will be used to develop recommendations for equitable access.


Options:
A: Arm Label: Free combination; Type: ACTIVE_COMPARATOR; Interventions: Drug: perindopril, indapamide , amlodipine | Arm Label: Tripliam; Type: ACTIVE_COMPARATOR; Interventions: Drug: Tripliam (perindopril, indapamide, amlodipine) | Intervention Type: DRUG; Name: perindopril, indapamide , amlodipine; Assigned to Arm(s): Free combination | Intervention Type: DRUG; Name: Tripliam (perindopril, indapamide, amlodipine); Assigned to Arm(s): Tripliam
B: Arm Label: FDC Fixed Dose Combination; Type: EXPERIMENTAL; Interventions: Drug: FDC | Arm Label: Conventional treatment; Type: ACTIVE_COMPARATOR; Interventions: Drug: Separately drugs, simvastatin, aspirin and ramipril | Intervention Type: DRUG; Name: FDC; Assigned to Arm(s): FDC Fixed Dose Combination | Intervention Type: DRUG; Name: Separately drugs, simvastatin, aspirin and ramipril; Assigned to Arm(s): Conventional treatment
C: Arm Label: OM40/AML10; Type: EXPERIMENTAL; Interventions: Drug: Olmesartan medoxomil, Drug: Amlodipine | Arm Label: OM40/HCTZ25; Type: ACTIVE_COMPARATOR; Interventions: Drug: Olmesartan medoxomil, Drug: Hydrochlorothiazide | Arm Label: AML10/HCTZ25; Type: ACTIVE_COMPARATOR; Interventions: Drug: Amlodipine, Drug: Hydrochlorothiazide | Arm Label: OM40/AML10/HCTZ25; Type: ACTIVE_COMPARATOR; Interventions: Drug: Olmesartan medoxomil, Drug: Amlodipine, Drug: Hydrochlorothiazide | Intervention Type: DRUG; Name: Olmesartan medoxomil; Assigned to Arm(s): OM40/AML10, OM40/AML10/HCTZ25, OM40/HCTZ25 | Intervention Type: DRUG; Name: Amlodipine; Assigned to Arm(s): AML10/HCTZ25, OM40/AML10, OM40/AML10/HCTZ25 | Intervention Type: DRUG; Name: Hydrochlorothiazide; Assigned to Arm(s): AML10/HCTZ25, OM40/AML10/HCTZ25, OM40/HCTZ25
D: Arm Label: polypill; Type: EXPERIMENTAL; Interventions: Drug: polypill | Arm Label: Usual Care; Type: ACTIVE_COMPARATOR; Interventions: Drug: Usual cardiovascular medications | Intervention Type: DRUG; Name: polypill; Assigned to Arm(s): polypill | Intervention Type: DRUG; Name: Usual cardiovascular medications; Assigned to Arm(s): Usual Care

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomised Controlled Trial of a Fixed-dose Combination Polypill Medication (the Red Heart Pill) and Usual Care in Those at High Risk of Cardiovascular Disease.
Brief Summary: People with established cardiovascular disease need secondary prevention that addresses multiple risk factors. Complexity \& cost confer particularly difficult barriers to uptake of treatment; recovery from a stroke or heart attack typically necessitates multiple drugs for cholesterol, blood pressure and platelet function. A low-cost, fixed-dose, once-daily combination polypill, the Red Heart Pill, has been formulated by Dr Reddy's Laboratories. UMPIRE will evaluate whether provision of this polypill compared with usual medications improves adherence and clinical outcomes among high-risk patients in Europe and India. The results will be used to develop recommendations for equitable access.


Options:
A: Arm Label: polypill; Type: EXPERIMENTAL; Interventions: Drug: polypill | Arm Label: Usual Care; Type: ACTIVE_COMPARATOR; Interventions: Drug: Usual cardiovascular medications | Intervention Type: DRUG; Name: polypill; Assigned to Arm(s): polypill | Intervention Type: DRUG; Name: Usual cardiovascular medications; Assigned to Arm(s): Usual Care
B: Intervention Type: BEHAVIORAL; Name: Set of supportive tools/measures vs. standard care; Assigned to Arm(s): N/A
C: Arm Label: CHESS + Case Mgt; Type: EXPERIMENTAL; Interventions: Behavioral: CHESS Internet telehealth | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: CHESS Internet telehealth; Assigned to Arm(s): CHESS + Case Mgt
D: Intervention Type: BEHAVIORAL; Name: Comprehensive pharmacy care program; Assigned to Arm(s): N/A

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomised Controlled Trial of a Fixed-dose Combination Polypill Medication (the Red Heart Pill) and Usual Care in Those at High Risk of Cardiovascular Disease.
Brief Summary: People with established cardiovascular disease need secondary prevention that addresses multiple risk factors. Complexity \& cost confer particularly difficult barriers to uptake of treatment; recovery from a stroke or heart attack typically necessitates multiple drugs for cholesterol, blood pressure and platelet function. A low-cost, fixed-dose, once-daily combination polypill, the Red Heart Pill, has been formulated by Dr Reddy's Laboratories. UMPIRE will evaluate whether provision of this polypill compared with usual medications improves adherence and clinical outcomes among high-risk patients in Europe and India. The results will be used to develop recommendations for equitable access.


Options:
A: Arm Label: polypill; Type: EXPERIMENTAL; Interventions: Drug: polypill | Arm Label: Usual Care; Type: ACTIVE_COMPARATOR; Interventions: Drug: Usual cardiovascular medications | Intervention Type: DRUG; Name: polypill; Assigned to Arm(s): polypill | Intervention Type: DRUG; Name: Usual cardiovascular medications; Assigned to Arm(s): Usual Care
B: Intervention Type: DRUG; Name: Aspirin; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Clopidogrel; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Simvastatin; Assigned to Arm(s): N/A
C: Intervention Type: DRUG; Name: Aggrenox bid (ASA 25mg/Dipyridamole ER 200mg); Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: ASA 100 mg qd; Assigned to Arm(s): N/A
D: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Drug: Best medical therapy | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Device: STARFlex septal closure system | Intervention Type: DEVICE; Name: STARFlex septal closure system; Assigned to Arm(s): 2 | Intervention Type: DRUG; Name: Best medical therapy; Assigned to Arm(s): 1

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomised Controlled Trial Comparing TVT, Pelvicol and Autologous Fascial Slings for the Treatment of Stress Urinary Incontinence in Women
Brief Summary: The purpose of this trial was to discover which type of operation for stress urinary incontinence in women offered better results: autologous slings, TVT or Pelvicol slings.


Options:
A: Arm Label: 2; Type: N/A; Interventions: Procedure: AFS and TVT | Intervention Type: PROCEDURE; Name: AFS and TVT; Assigned to Arm(s): 2
B: Arm Label: Burch; Type: OTHER; Interventions: Procedure: Burch Modified Tanagho | Arm Label: Sling; Type: OTHER; Interventions: Procedure: Autologous Fascia Sling | Intervention Type: PROCEDURE; Name: Burch Modified Tanagho; Assigned to Arm(s): Burch | Intervention Type: PROCEDURE; Name: Autologous Fascia Sling; Assigned to Arm(s): Sling
C: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Procedure: retropubic mid-urethral sling (TVT) | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Procedure: transobturator mid-urethral sling (TVT-O and the Monarc) | Intervention Type: PROCEDURE; Name: retropubic mid-urethral sling (TVT); Assigned to Arm(s): 1 | Intervention Type: PROCEDURE; Name: transobturator mid-urethral sling (TVT-O and the Monarc); Assigned to Arm(s): 2
D: Arm Label: Autologous Fascial Sling; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Autologous fascial sling | Arm Label: TVT; Type: ACTIVE_COMPARATOR; Interventions: Procedure: TVT | Arm Label: Pelvicol; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Pelvicol | Intervention Type: PROCEDURE; Name: Autologous fascial sling; Assigned to Arm(s): Autologous Fascial Sling | Intervention Type: PROCEDURE; Name: TVT; Assigned to Arm(s): TVT | Intervention Type: PROCEDURE; Name: Pelvicol; Assigned to Arm(s): Pelvicol

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A PHASE 3B MULTICENTER, DOUBLE-BLIND, RANDOMIZED WITHDRAWAL EFFICACY AND SAFETY STUDY OF PREGABALIN IN THE TREATMENT OF PATIENTS WITH INADEQUATELY TREATED PAINFUL DIABETIC PERIPHERAL NEUROPATHY
Brief Summary: Patients will be switched from their current medication for painful diabetic peripheral neuropathy to evaluate the safety and efficacy of pregabalin as compared to placebo. All patients will receive pregabalin, and half of patients will receive placebo at some point during the study.


Options:
A: Arm Label: pregabalin (Lyrica); Type: EXPERIMENTAL; Interventions: Drug: pregabalin (Lyrica) | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: pregabalin (Lyrica); Assigned to Arm(s): pregabalin (Lyrica) | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
B: Intervention Type: DRUG; Name: Pregabalin; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Duloxetine; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Amitriptyline; Assigned to Arm(s): N/A
C: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Drug: Comparator: pregabalin | Arm Label: B; Type: PLACEBO_COMPARATOR; Interventions: Drug: Comparator: Placebo (unspecified) | Intervention Type: DRUG; Name: Comparator: pregabalin; Assigned to Arm(s): A | Intervention Type: DRUG; Name: Comparator: Placebo (unspecified); Assigned to Arm(s): B
D: Intervention Type: DRUG; Name: pregabalin; Assigned to Arm(s): N/A

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Chiropractic and Exercise Management of Spinal Dysfunction in Seniors
Brief Summary: This study will compare the effectiveness of chiropractic and exercise treatment in the short- and long-term, when managing chronic neck and back disability in seniors over the age of 65 years.


Options:
A: Arm Label: 9 months of chiropractic care and exercise; Type: EXPERIMENTAL; Interventions: Other: chiropractic, Behavioral: exercise | Arm Label: 3 months of chiropractic care and exercise; Type: ACTIVE_COMPARATOR; Interventions: Other: chiropractic, Behavioral: exercise | Intervention Type: OTHER; Name: chiropractic; Assigned to Arm(s): 3 months of chiropractic care and exercise, 9 months of chiropractic care and exercise | Intervention Type: BEHAVIORAL; Name: exercise; Assigned to Arm(s): 3 months of chiropractic care and exercise, 9 months of chiropractic care and exercise
B: Intervention Type: PROCEDURE; Name: Chiropractic spinal manipulation; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Acetaminophen; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: Self-care; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Non-Steroidal anti-inflammatory drugs (NSAIDS); Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Tylenol with codeine; Assigned to Arm(s): N/A
C: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Other: manual therapy, Other: exercise | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Other: exercise | Intervention Type: OTHER; Name: manual therapy; Assigned to Arm(s): 1 | Intervention Type: OTHER; Name: exercise; Assigned to Arm(s): 1, 2
D: Arm Label: 1; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Other: spinal manipulation | Arm Label: 3; Type: EXPERIMENTAL; Interventions: Other: Spinal manipulation + exercises | Intervention Type: OTHER; Name: spinal manipulation; Assigned to Arm(s): 2 | Intervention Type: OTHER; Name: Spinal manipulation + exercises; Assigned to Arm(s): 3

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Meditation and Exercise for Prevention of Acute Respiratory Infection
Brief Summary: The overarching goal of this project is to determine whether mind-body practices such as meditation or exercise can reduce the public health burden of acute respiratory infection. A major secondary goal is to determine whether mindfulness meditation or moderately strenuous exercise can enhance immune processes such as antibody response to influenza vaccination (flu shots). Finally, we want to investigate the influence of stress, optimism, anxiety and positive and negative emotion on immunity and resistance to respiratory infection.


Options:
A: Arm Label: Usual Care; Type: ACTIVE_COMPARATOR; Interventions: Other: Usual Care | Arm Label: Standardized Rehabilitation; Type: OTHER; Interventions: Other: Standardized Rehabilitation | Intervention Type: OTHER; Name: Standardized Rehabilitation; Assigned to Arm(s): Standardized Rehabilitation | Intervention Type: OTHER; Name: Usual Care; Assigned to Arm(s): Usual Care
B: Arm Label: Mindfulness Meditation; Type: EXPERIMENTAL; Interventions: Other: Mindfulness Meditation | Arm Label: Exercise; Type: EXPERIMENTAL; Interventions: Other: Exercise | Arm Label: Wait-list control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Mindfulness Meditation; Assigned to Arm(s): Mindfulness Meditation | Intervention Type: OTHER; Name: Exercise; Assigned to Arm(s): Exercise
C: Arm Label: Meditation; Type: EXPERIMENTAL; Interventions: Behavioral: Meditation | Arm Label: Exercise; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise | Arm Label: Waiting list control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Meditation; Assigned to Arm(s): Meditation | Intervention Type: BEHAVIORAL; Name: Exercise; Assigned to Arm(s): Exercise
D: Arm Label: Physical Activity; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Physical Activity | Arm Label: Successful Aging; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Successful Aging | Intervention Type: BEHAVIORAL; Name: Physical Activity; Assigned to Arm(s): Physical Activity | Intervention Type: BEHAVIORAL; Name: Successful Aging; Assigned to Arm(s): Successful Aging

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Nurse Managed Upper Body Strength Training in COPD
Brief Summary: This is a four month exercise training program for people with chronic obstructive pulmonary disease (COPD)with a 12 month follow-up.


Options:
A: Arm Label: 18 mcg tiotropium; Type: ACTIVE_COMPARATOR; Interventions: Drug: Tiotropium | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: Tiotropium; Assigned to Arm(s): 18 mcg tiotropium | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
B: Arm Label: Pedometer-based activity promotion; Type: EXPERIMENTAL; Interventions: Behavioral: Pedometer-based activity promotion, Other: Pulmonary rehabilitation (Standard care) | Arm Label: Short patient education and exercise; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Short patient education and exercise, Other: Pulmonary rehabilitation (Standard care) | Intervention Type: BEHAVIORAL; Name: Pedometer-based activity promotion; Assigned to Arm(s): Pedometer-based activity promotion | Intervention Type: BEHAVIORAL; Name: Short patient education and exercise; Assigned to Arm(s): Short patient education and exercise | Intervention Type: OTHER; Name: Pulmonary rehabilitation (Standard care); Assigned to Arm(s): Pedometer-based activity promotion, Short patient education and exercise
C: Intervention Type: DEVICE; Name: Noninvasive positive pressure ventilation; Assigned to Arm(s): N/A
D: Arm Label: Upper Body Strength Training with Self-Efficacy; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise-specific self-efficacy, Behavioral: upper body strength training | Arm Label: Upper body strength training; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: upper body strength training | Arm Label: Chair exercise; Type: SHAM_COMPARATOR; Interventions: Behavioral: Gentle chair exercise | Intervention Type: BEHAVIORAL; Name: Exercise-specific self-efficacy; Assigned to Arm(s): Upper Body Strength Training with Self-Efficacy | Intervention Type: BEHAVIORAL; Name: Gentle chair exercise; Assigned to Arm(s): Chair exercise | Intervention Type: BEHAVIORAL; Name: upper body strength training; Assigned to Arm(s): Upper Body Strength Training with Self-Efficacy, Upper body strength training

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Sequenced Atypical Antipsychotics Therapy With Intensive or Basic Psychosocial Intervention for First-episode Schizophrenia: An Effectiveness Study
Brief Summary: Schizophrenia is not a curable but a treatable disease by antipsychotics. Kinds of atypical antipsychotics are widely used since 1990s' in China. Although their efficacy for acute phase are all better than typicals, individulized regimen of them for first-episode schizophrenia and their effectiveness in real naturalistic clinical settings still remain unclear. And those patients also need more comprehensive intervention such as psychosocial programs to improve their function. This protocol is to conduct a study in several sites of China to investigate the effectiveness of comprehensive intervention combining sequenced atypical antipsychotic therapy and intensive psychosocial intervention for first-episode schizophrenic patients. In addition, this protocol also aims at collecting such information as molecular genetics, neurochemical test, neucognitive performance and neuroimaging for outcome analysis.


Options:
A: Arm Label: A; Type: EXPERIMENTAL; Interventions: Drug: aripiprazole | Arm Label: B; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Intervention Type: DRUG; Name: aripiprazole; Assigned to Arm(s): A | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): B
B: Intervention Type: DRUG; Name: Risperidone; Assigned to Arm(s): N/A
C: Intervention Type: DRUG; Name: aripiprazole; Assigned to Arm(s): N/A
D: Arm Label: Risperidone, Intensive; Type: EXPERIMENTAL; Interventions: Drug: risperidone | Arm Label: risperidone, basic; Type: ACTIVE_COMPARATOR; Interventions: Drug: risperidone | Arm Label: olanzapine, intensive; Type: EXPERIMENTAL; Interventions: Drug: olanzapine | Arm Label: olanzapine, basic; Type: ACTIVE_COMPARATOR; Interventions: Drug: olanzapine | Arm Label: aripiprazole, intensive; Type: EXPERIMENTAL; Interventions: Drug: Aripiprazole | Arm Label: aripiprazole, basiv; Type: ACTIVE_COMPARATOR; Interventions: Drug: Aripiprazole | Intervention Type: DRUG; Name: risperidone; Assigned to Arm(s): Risperidone, Intensive, risperidone, basic | Intervention Type: DRUG; Name: olanzapine; Assigned to Arm(s): olanzapine, basic, olanzapine, intensive | Intervention Type: DRUG; Name: Aripiprazole; Assigned to Arm(s): aripiprazole, basiv, aripiprazole, intensive

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Randomized Trial of Intensive Physical Therapy for Patients With Acute Respiratory Failure
Brief Summary: Acute respiratory failure is a heterogeneous disorder that results in more than 300,000 Americans requiring admission to an intensive care unit for invasive mechanical ventilatory support each year. Though acute respiratory failure is a pulmonary disorder, patients who survive their hospitalization are not limited by respiratory symptoms after discharge. Rather persistent neuromuscular weakness is the primary disorder that adversely alters their quality of life and ability to function on a daily basis. In this application the investigators plan to conduct a randomized clinical trial called the Do It Now study (Diagnosis and Treatment of Neuromuscular Weakness) to determine the effectiveness of an intensive physical therapy program for patients recovering from acute respiratory failure. This trial will establish the efficacy of the physical therapy programs that is currently performed for patients with acute respiratory failure in a non-evidence based manner across the United States.


Options:
A: Arm Label: Intervention; Type: ACTIVE_COMPARATOR; Interventions: Other: High-protein diet and resistance training | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: High-protein diet and resistance training; Assigned to Arm(s): Intervention
B: Arm Label: Intensive physical therapy; Type: EXPERIMENTAL; Interventions: Procedure: intensive physical therapy | Arm Label: control group; Type: ACTIVE_COMPARATOR; Interventions: Procedure: control group | Intervention Type: PROCEDURE; Name: intensive physical therapy; Assigned to Arm(s): Intensive physical therapy | Intervention Type: PROCEDURE; Name: control group; Assigned to Arm(s): control group
C: Arm Label: Experimental group; Type: EXPERIMENTAL; Interventions: Other: Experimental group | Arm Label: Control group; Type: ACTIVE_COMPARATOR; Interventions: Other: Control group | Intervention Type: OTHER; Name: Experimental group; Assigned to Arm(s): Experimental group | Intervention Type: OTHER; Name: Control group; Assigned to Arm(s): Control group
D: Arm Label: Exercise; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Exercise | Arm Label: Control group; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Control | Intervention Type: BEHAVIORAL; Name: Exercise; Assigned to Arm(s): Exercise | Intervention Type: BEHAVIORAL; Name: Control; Assigned to Arm(s): Control group

Answer: B