Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomised, Double Blind, Parallel Group Study to Assess the Efficacy and Safety of 12 Weeks of Once Daily, Orally Inhaled, Co-administration of Olodaterol 5µg (Delivered by the Respimat® Inhaler) and Tiotropium 18µg (Delivered by the HandiHaler®) Compared to Once Daily, Orally Inhaled, Co-administration of Placebo (Delivered by the Respimat® Inhaler) and Tiotropium 18µg (Delivered by the HandiHaler®) in Patients With Chronic Obstructive Pulmonary Disease (COPD)[ANHELTO TM 2]
Brief Summary: The overall objective of this study is to assess efficacy and safety of 12 weeks, once daily, orally inhaled co-administration of olodaterol 5 µg (delivered by the Respimat® Inhaler) and tiotropium (delivered by the Handihaler® as Spiriva Handihaler®), compared to tiotropium (Spiriva Handihaler®) monotherapy on lung function in patients with COPD.


Options:
A: Arm Label: tiotropium + olodaterol low dose; Type: EXPERIMENTAL; Interventions: Drug: tiotropium, Drug: olodaterol | Arm Label: tiotropium + olodaterol high dose; Type: EXPERIMENTAL; Interventions: Drug: tiotropium, Drug: olodaterol | Arm Label: tiotropium; Type: ACTIVE_COMPARATOR; Interventions: Drug: tiotropium | Arm Label: placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Intervention Type: DRUG; Name: tiotropium; Assigned to Arm(s): tiotropium + olodaterol high dose | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): placebo | Intervention Type: DRUG; Name: olodaterol; Assigned to Arm(s): tiotropium + olodaterol high dose | Intervention Type: DRUG; Name: tiotropium; Assigned to Arm(s): tiotropium + olodaterol low dose | Intervention Type: DRUG; Name: tiotropium; Assigned to Arm(s): tiotropium | Intervention Type: DRUG; Name: olodaterol; Assigned to Arm(s): tiotropium + olodaterol low dose
B: Arm Label: tiotropium + olodaterol low dose; Type: EXPERIMENTAL; Interventions: Drug: olodaterol, Drug: tiotropium | Arm Label: tiotropium + olodaterol high dose; Type: EXPERIMENTAL; Interventions: Drug: olodaterol, Drug: tiotropium | Arm Label: tiotropium; Type: ACTIVE_COMPARATOR; Interventions: Drug: tiotropium | Arm Label: placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Intervention Type: DRUG; Name: olodaterol; Assigned to Arm(s): tiotropium + olodaterol high dose, tiotropium + olodaterol low dose | Intervention Type: DRUG; Name: tiotropium; Assigned to Arm(s): tiotropium, tiotropium + olodaterol high dose, tiotropium + olodaterol low dose | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): placebo
C: Arm Label: Olodaterol andTiotropium; Type: EXPERIMENTAL; Interventions: Drug: Tiotropium, Drug: Olodaterol | Arm Label: Placebo and Tiotropium; Type: OTHER; Interventions: Drug: Tiotropium, Drug: Placebo matching Olodaterol | Intervention Type: DRUG; Name: Tiotropium; Assigned to Arm(s): Placebo and Tiotropium | Intervention Type: DRUG; Name: Placebo matching Olodaterol; Assigned to Arm(s): Placebo and Tiotropium | Intervention Type: DRUG; Name: Tiotropium; Assigned to Arm(s): Olodaterol andTiotropium | Intervention Type: DRUG; Name: Olodaterol; Assigned to Arm(s): Olodaterol andTiotropium
D: Arm Label: tiotropium+olodaterol low dose FDC; Type: EXPERIMENTAL; Interventions: Drug: tiotropium + olodaterol, Device: Respimat | Arm Label: tiotropium+olodaterol high dose FDC; Type: EXPERIMENTAL; Interventions: Drug: tiotropium + olodaterol, Device: Respimat | Arm Label: olodaterol; Type: ACTIVE_COMPARATOR; Interventions: Drug: olodaterol, Device: Respimat | Arm Label: tiotropium low dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: tiotropium, Device: Respimat | Arm Label: tiotropium high dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: tiotropium, Device: Respimat | Intervention Type: DRUG; Name: tiotropium + olodaterol; Assigned to Arm(s): tiotropium+olodaterol low dose FDC | Intervention Type: DRUG; Name: tiotropium; Assigned to Arm(s): tiotropium low dose | Intervention Type: DRUG; Name: olodaterol; Assigned to Arm(s): olodaterol | Intervention Type: DRUG; Name: tiotropium; Assigned to Arm(s): tiotropium high dose | Intervention Type: DRUG; Name: tiotropium + olodaterol; Assigned to Arm(s): tiotropium+olodaterol high dose FDC | Intervention Type: DEVICE; Name: Respimat; Assigned to Arm(s): olodaterol, tiotropium high dose, tiotropium low dose, tiotropium+olodaterol high dose FDC, tiotropium+olodaterol low dose FDC

Answer: C