Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized Controlled Study of YONDELIS (Trabectedin) or Dacarbazine for the Treatment of Advanced Liposarcoma or Leiomyosarcoma
Brief Summary: The purpose of this study is to evaluate whether overall survival for the trabectedin group is superior to the dacarbazine group for patients with advanced L-sarcoma (liposarcoma or leiomyosarcoma).


Options:
A: Intervention Type: BIOLOGICAL; Name: pegfilgrastim; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: doxorubicin hydrochloride; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: ifosfamide; Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: multimodality therapy; Assigned to Arm(s): N/A
B: Arm Label: Group 1; Type: EXPERIMENTAL; Interventions: Biological: dactinomycin, Drug: doxorubicin hydrochloride, Drug: etoposide, Drug: ifosfamide, Drug: vincristine sulfate, Procedure: conventional surgery, Radiation: radiation therapy | Arm Label: Group 2, arm I; Type: EXPERIMENTAL; Interventions: Biological: dactinomycin, Drug: doxorubicin hydrochloride, Drug: etoposide, Drug: ifosfamide, Drug: vincristine sulfate, Procedure: conventional surgery, Radiation: radiation therapy | Arm Label: Group 2, arm II; Type: EXPERIMENTAL; Interventions: Biological: dactinomycin, Drug: busulfan, Drug: doxorubicin hydrochloride, Drug: etoposide, Drug: ifosfamide, Drug: melphalan, Drug: vincristine sulfate, Procedure: autologous hematopoietic stem cell transplantation, Procedure: conventional surgery, Radiation: radiation therapy | Intervention Type: BIOLOGICAL; Name: dactinomycin; Assigned to Arm(s): Group 1, Group 2, arm I, Group 2, arm II | Intervention Type: DRUG; Name: busulfan; Assigned to Arm(s): Group 2, arm II | Intervention Type: DRUG; Name: doxorubicin hydrochloride; Assigned to Arm(s): Group 1, Group 2, arm I, Group 2, arm II | Intervention Type: DRUG; Name: etoposide; Assigned to Arm(s): Group 1, Group 2, arm I, Group 2, arm II | Intervention Type: DRUG; Name: ifosfamide; Assigned to Arm(s): Group 1, Group 2, arm I, Group 2, arm II | Intervention Type: DRUG; Name: melphalan; Assigned to Arm(s): Group 2, arm II | Intervention Type: DRUG; Name: vincristine sulfate; Assigned to Arm(s): Group 1, Group 2, arm I, Group 2, arm II | Intervention Type: PROCEDURE; Name: autologous hematopoietic stem cell transplantation; Assigned to Arm(s): Group 2, arm II | Intervention Type: PROCEDURE; Name: conventional surgery; Assigned to Arm(s): Group 1, Group 2, arm I, Group 2, arm II | Intervention Type: RADIATION; Name: radiation therapy; Assigned to Arm(s): Group 1, Group 2, arm I, Group 2, arm II
C: Arm Label: Regimen A; Type: EXPERIMENTAL; Interventions: Biological: filgrastim, Drug: cyclophosphamide, Drug: doxorubicin hydrochloride, Drug: etoposide, Drug: ifosfamide, Drug: vincristine sulfate, Procedure: adjuvant therapy, Procedure: conventional surgery, Procedure: neoadjuvant therapy, Radiation: brachytherapy, Radiation: radiation therapy | Arm Label: Regimen B; Type: EXPERIMENTAL; Interventions: Biological: filgrastim, Drug: cyclophosphamide, Drug: doxorubicin hydrochloride, Drug: etoposide, Drug: ifosfamide, Drug: vincristine sulfate, Procedure: adjuvant therapy, Procedure: conventional surgery, Procedure: neoadjuvant therapy, Radiation: brachytherapy, Radiation: radiation therapy | Intervention Type: BIOLOGICAL; Name: filgrastim; Assigned to Arm(s): Regimen A, Regimen B | Intervention Type: DRUG; Name: cyclophosphamide; Assigned to Arm(s): Regimen A, Regimen B | Intervention Type: DRUG; Name: doxorubicin hydrochloride; Assigned to Arm(s): Regimen A, Regimen B | Intervention Type: DRUG; Name: etoposide; Assigned to Arm(s): Regimen A, Regimen B | Intervention Type: DRUG; Name: ifosfamide; Assigned to Arm(s): Regimen A, Regimen B | Intervention Type: DRUG; Name: vincristine sulfate; Assigned to Arm(s): Regimen A, Regimen B | Intervention Type: PROCEDURE; Name: adjuvant therapy; Assigned to Arm(s): Regimen A, Regimen B | Intervention Type: PROCEDURE; Name: conventional surgery; Assigned to Arm(s): Regimen A, Regimen B | Intervention Type: PROCEDURE; Name: neoadjuvant therapy; Assigned to Arm(s): Regimen A, Regimen B | Intervention Type: RADIATION; Name: brachytherapy; Assigned to Arm(s): Regimen A, Regimen B | Intervention Type: RADIATION; Name: radiation therapy; Assigned to Arm(s): Regimen A, Regimen B
D: Arm Label: Trabectedin; Type: EXPERIMENTAL; Interventions: Drug: Trabectedin | Arm Label: Dacarbazine; Type: ACTIVE_COMPARATOR; Interventions: Drug: Dacarbazine | Intervention Type: DRUG; Name: Trabectedin; Assigned to Arm(s): Trabectedin | Intervention Type: DRUG; Name: Dacarbazine; Assigned to Arm(s): Dacarbazine

Answer: D