Please select the eligibility criteria that correspond to the clinical trial below.
Title: HeartHab: a Prospective Cross-over Trial Investigating the Effectiveness of an App Based Telerehabilitation Program on Exercise Capacity, Lifestyle and Risk Factors in Patients With Coronary Artery Disease
Brief Summary: The recurrence of major cardiac events after infarction is very high, in some populations up to 20% in the first year. Optimal secondary prevention as organized in cardiac rehabilitation centers is effective in reducing both morbidity and mortality. However, many studies have shown that the participation and adherence rate in CR-programs is low in most European countries. Therefore, novel ways of delivering secondary prevention using information technology and self-monitoring are being explored. Hence, this study will investigate the effectiveness of a mobile, patient tailored, app based multidisciplinary telerehabilitation program (HeartHab app) in improving exercise capacity, lifestyle and risk factors in patients with coronary artery disease in a post-rehabilitation setting.


Options:
A: Inclusion Criteria:

* Underactive adults (\< 60 minutes of moderate intensity exercise per week in the last month)
* Diagnosis of a physical/mobility disability by their physician
* Working age adult 18 to 70 yrs. of age
* No physician contraindications to exercise and written physician approval to participate in the study
* Not currently enrolled in a structured exercise program over the past 6 months
* Have the ability to use upper, lower or both sets of extremities to exercise
* Must have the ability to converse and read English

Exclusion Criteria:

* Medically unstable to perform home exercise as determined by their physician
* High level tetraplegia and unable to use arms or legs to exercise
* Cognitive impairment that may preclude self-directed daily activities
* No internet access.
B: Inclusion Criteria:

* History of coronary artery disease with or without intervention (PCI/CABG/conservative)
* History of a cardiac rehabilitation (CR) program
* Clinically stable without inducible ischemia or high risk ventricular arrhythmia, confirmed by the last available maximal ergospirometry test
* Age ≥18 years
* Willing and physically able to follow an app based telerehabilitation program and other study procedures in a four months follow-up period
* Evidence of a personally signed and dated informed consent, indicating that the subject (or legally-recognised representative) has been informed of all pertinent aspects of the study
* Possession of and/or able to use an Android smartphone
* Dutch speaking and understanding

Exclusion Criteria:

* Recent PCI or CABG procedure, and still included in a CR program
* Orthopedic, neurologic or any other pathologic condition which makes the patient physically unable to follow an app based telerehabilitation program
* Planned interventional procedure or surgery in the next four months
* Pregnant females
* Present cardiovascular complaints
* Participation in other cardiac rehabilitation program trials, focusing on exercise outcome
* Any condition which in the opinion of the investigator would make it unsafe or unsuitable for the patient to participate in this study or a life expectancy of less than 4 months based on investigators judgement
C: Inclusion Criteria:

* A confirmed diagnosis of MS
* Known to a MS consultant in NHS Ayrshire and Arran, Lothian or Plymouth Hospitals NHS Trust
* EDSS of 4 - 6.5
* Access to a personal computer/tablet or smart television with an email address and internet connection

Exclusion Criteria:

* Currently taking part in regular exercise (two or more times per week) and/or a regular physiotherapy programme
* Poor cognitive function as assessed by a Mini Mental State Examination Score (MMSE) \<24
* Any significant change in medication (within the last 3 months)
* Relapse within 3 months requiring treatment
* Other significant co-morbidities for which exercise is contra-indicated
* Unwilling to be randomised to intervention/control group
* Currently participating in another clinical trial (rehabilitation or pharmacological)
D: Inclusion Criteria:

* Women and men above 18 years
* Must have signed the "Informed Consent" document
* Must be able to understand study information
* Must live in Hjørring or Frederikshavn Kommune
* Must have mobile network
* Must be able to use IT or have a near person who can use IT
* Patients with clinical diagnosis of Heart Failure, Myocardial Infarction, Angina Pectoris, patients who have had Coronary-Artery Bypass Surgery.

Exclusion Criteria:

* Patients who, according to investigator, will not be able to participate in the study
* Lack of ability to speak and understand Danish
* Pregnancy or nursing
* Neurologic disease
* Use of wheelchair/lack of ability to walk
* Participation in other studies which can influence the outcomes of this study

Answer: B