Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Foley OR MisO for the Management of Induction (FOR MOMI) Trial
Brief Summary: The percentage of women undergoing an induction of labor (IOL) is estimated to be 20% and continues to rise. Simultaneously, the cesarean delivery (CD) rate has continued to increase (2). Induction is a known risk factor for CD. Despite numerous studies evaluating time periods to define a failed IOL, there are no guidelines or accepted definitions of when to call an IOL failed given the incremental gain in vaginal delivery when IOL is prolonged. While decreasing the CD rate is an important primary focus in obstetrics, attention must also be paid to the overall length of labor given that prolonged labor is associated with adverse maternal and neonatal outcomes. Furthermore, a prolonged labor is associated with an increase in direct hospital costs and healthcare utilization. The use of cervical ripening agents, such as vaginal prostaglandin and mechanical dilators, has been demonstrated to reduce labor time and CD rate. In addition to specific individual agents, certain dosing and regimens for IOL and active labor have been compared to evaluate whether a particular dose or regimen can decrease the length of labor and decrease the CD rate. Most of these regimens; however, focus on individual induction agents and few have compared the efficacy of using more than one agent simultaneously. Given the associated risks of prolonged labor and limited data evaluating the use of combined cervical ripening agents, our objective is to evaluate the difference in time to delivery among women who undergo an IOL with four different methods.


Options:
A: Arm Label: Nulliparous - Foley only; Type: ACTIVE_COMPARATOR; Interventions: Device: Transcervical Foley catheter | Arm Label: Nulliparous - Foley and oxytocin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Oxytocin, Device: Transcervical Foley catheter | Arm Label: Multi(primi)parous - Foley only; Type: ACTIVE_COMPARATOR; Interventions: Device: Transcervical Foley catheter | Arm Label: Multi(primi)parous - Foley and oxytocin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Oxytocin, Device: Transcervical Foley catheter | Intervention Type: DRUG; Name: Oxytocin; Assigned to Arm(s): Multi(primi)parous - Foley and oxytocin, Nulliparous - Foley and oxytocin | Intervention Type: DEVICE; Name: Transcervical Foley catheter; Assigned to Arm(s): Multi(primi)parous - Foley and oxytocin, Multi(primi)parous - Foley only, Nulliparous - Foley and oxytocin, Nulliparous - Foley only
B: Arm Label: weighted bag; Type: ACTIVE_COMPARATOR; Interventions: Other: weighted bag | Arm Label: leg taping; Type: ACTIVE_COMPARATOR; Interventions: Other: leg taping | Intervention Type: OTHER; Name: weighted bag; Assigned to Arm(s): weighted bag | Intervention Type: OTHER; Name: leg taping; Assigned to Arm(s): leg taping
C: Arm Label: Cervical foley & Misoprostol; Type: EXPERIMENTAL; Interventions: Device: Cervical Foley & Misoprostol | Arm Label: Misoprostol only; Type: EXPERIMENTAL; Interventions: Drug: Misoprostol Alone | Arm Label: Cervical foley alone; Type: EXPERIMENTAL; Interventions: Device: Cervical Foley Alone | Arm Label: Cervical foley & Pitocin; Type: EXPERIMENTAL; Interventions: Device: Cervical Foley & Pitocin | Intervention Type: DEVICE; Name: Cervical Foley & Misoprostol; Assigned to Arm(s): Cervical foley & Misoprostol | Intervention Type: DRUG; Name: Misoprostol Alone; Assigned to Arm(s): Misoprostol only | Intervention Type: DEVICE; Name: Cervical Foley Alone; Assigned to Arm(s): Cervical foley alone | Intervention Type: DEVICE; Name: Cervical Foley & Pitocin; Assigned to Arm(s): Cervical foley & Pitocin
D: Arm Label: folye catheter plus vaginal IMN; Type: EXPERIMENTAL; Interventions: Device: foley catheter, Drug: Vaginal IMN | Arm Label: Misoprostol vaginally; Type: ACTIVE_COMPARATOR; Interventions: Drug: Misoprostol | Intervention Type: DEVICE; Name: foley catheter; Assigned to Arm(s): folye catheter plus vaginal IMN | Intervention Type: DRUG; Name: Misoprostol; Assigned to Arm(s): Misoprostol vaginally | Intervention Type: DRUG; Name: Vaginal IMN; Assigned to Arm(s): folye catheter plus vaginal IMN

Answer: C