Please select the eligibility criteria that correspond to the clinical trial below.
Title: Pilot Study to Test the Efficacy of a Worksite Intervention for Reducing Daily Sedentary Time and Improving Risk Factors for Cardiometabolic Disease Among Sedentary, Overweight, Full-time Working Adults
Brief Summary: The primary aim of this pilot study is to test the efficacy of a worksite intervention for reducing daily sedentary time and improving risk factors for cardiometabolic disease (e.g., measures of adiposity, anthropometrics, cardiorespiratory fitness) among sedentary, overweight, full-time working adults as compared to a waitlist control. A secondary aim will be to test pedal time at work as a measure of compliance with the intervention.


Options:
A: Inclusion Criteria:

* Adults between 21 and 65 years
* Sedentary (engaging in moderate intensity physical activity for less than 60 minutes per week)
* Working full time (35+ hours/week) at a sedentary desk dependant occupation
* Overweight (Body Mass Index \> 25.0 kg/m2 but less than 40.0 kg/2)
* Apparently healthy as assessed by a health history screening survey
* Devoid of overt complicated or acute cardiovascular, metabolic, respiratory, or neurological diseases
* Free from exercise/physical activity limitations

Exclusion Criteria:

* Adults with significant health problems exacerbated by exercise, such as uncontrolled hypertension, diabetes, orthopedic limitations, etc. will be excluded from the study. Note, with physician approval and adequate control of these health problems, these conditions will not necessarily preclude participation.
* Being unable to exercise
B: Inclusion Criteria:

* Diagnosed with RA (defined by the American College Rheumatology (ACR) criteria)
* Over the age of 18 years
* Self-reported sitting time for five hours or more per day (measured by Physical Activity Scale, PAS 2.1)
* Physical function score \<2.5 (measured by Health Assessment Questionnaire, HAQ)
* Informed consent
* Understand and speak Danish
* Access to mobile phone.

Exclusion Criteria:

* Severe physical disabilities (HAQ-score \> 2.5) which would prevent them from reducing daily sitting time (e.g. use of wheelchair);
* Pregnancy
* Vigorous physical activity for more than eight hours a week (measured by PAS 2,1).
C: Inclusion Criteria:

* Age 18-35 years
* Intending to be available for a 24 month intervention

Exclusion Criteria:

* Unable to provide informed consent
* BMI \< 18.5 kg/m2, \>/=35 kg/m2
* Household member on study staff
* Past or planned (within the next 24 months) weight loss surgery (e.g. gastric bypass, lap band, or liposuction); current participation in a commercial weight loss program (e.g. Weight Watcher's, Jenny Craig); current or planned enrollment in another diet/physical activity/weight loss intervention study
* Regular use of systemic steroids, prescription weight loss drugs, and/or diabetes medications (oral or injected). "Regular use" is defined as "taking this medication most days of the week for the previous month"
* Current treatment for an eating disorder
* Cardiovascular event (heart attack, stroke, episode of heart failure, or revascularization procedure) within the last 6 months
* Current treatment for malignancy (other than non-melanoma skin cancer)
* Investigator discretion
* Currently pregnant or gave birth within the last 6 months, currently lactating or breastfeeding within the last 3 months, actively planning pregnancy within the next 24 months.
* Systolic BP at screening \>/= 160 mmHg or diastolic BP \>/= 100 mmHg. If BP exceeds this level, participants can return for re-screening after being evaluated and treated for hypertension.
* Weight loss of more than 15 lbs over the past three months
* Trying to gain weight.
D: Inclusion Criteria:

* Participants were required to be sedentary, between 18-65 years old, have a BMI above 25.0 kg/m2 and physical inactive (not meeting the MVPA recommendations and not exceed 6000 steps/day). In addition subjects had to be free of any major disease with a general healthy status warranted.

Exclusion Criteria:

* Taking any medication or dietary supplements that may interfere with body composition or energy expenditure regulation, performing more than 5000 steps/day and meeting actual MVPA recommendations

Answer: A