Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Impact of Humeral Component Version on Outcomes Following Reverse Total Shoulder Arthroplasty: A Prospective Randomized Controlled Trial
Brief Summary: The proposed study is a prospective, single-blinded, randomized trial to investigate the impact of humeral component version on shoulder range of motion and patient reported functional outcomes following reverse total shoulder arthroplasty.


Options:
A: Inclusion Criteria:

* To be eligible for inclusion, a primary anatomic total shoulder arthroplasty must be indicated for the patient.

Exclusion Criteria:

* Age less than 18.
B: Inclusion Criteria:

1. Patients with shoulder osteoarthritis with cartilage defect of the caput humeri and not the glenoid cavity
2. Aged 18 years or older and fit
3. Informed, written consent -

Exclusion Criteria:

1. Patients found unsuitable preoperatively for a resurfacing prosthesis
2. Patients aged 85 or older
3. Patients with rheumatoid arthritis
4. Patients who previously had undergone shoulder alloplasty or other major shoulder surgery (more than just diagnostic arthroscopy)
5. Patients unable to avoid NSAID after surgery
6. Patients requiring regular systemic steroid treatment
7. Female patients taking hormone substitution
8. Patients with metabolic bone disease
9. Severe shoulder instability with large rotator cuff defect ( will often necessitate special prosthesis components or even major soft-tissue surgery)
10. Female patients in the fertile age range who do not use safe anti-conception (oral contraception, intrauterine devices, depot gestagens, vaginal hormone rings) -
C: Inclusion Criteria:

1. Primary osteoarthritis of the shoulder of grade III or higher (Kellgren and Lawrence modified for the shoulder
2. Patients who have failed standard conservative management of their shoulder osteoarthritis

Exclusion Criteria:

1. Patients with secondary OA resulting from major joint trauma, infection, avascular necrosis, cuff tear arthropathy, chronic dislocation, massive rotator cuff tear, inflammatory arthropathy, Charcot's arthropathy or previous shoulder surgery (other than arthroscopic debridement)
2. Patients with preoperative CT scans of the shoulder which show insufficient glenoid bone stock that would not allow for implantation of a glenoid prosthesis
3. Active joint or systemic infection
4. Significant muscle paralysis
5. Major medical illness (life expectancy less then 2yrs or unacceptably high operative risk)
6. Unable to speak or read English/French
7. Psychiatric illness that precludes informed consent
8. Unwilling to be followed for 2 years
D: Inclusion Criteria:

* Patients undergoing primary reverse total shoulder arthroplasty
* Diagnosis of cuff tear arthropathy or primary OA with RCT
* Intact posterior rotator cuff and subscapularis preoperatively, as determined by surgeon-administered physical exam
* 18 years or older

Exclusion Criteria:

* Revision arthroplasty
* Diagnosis of rheumatoid arthritis, infection, acute trauma or instability
* Minors (under 18 years of age)

  * Prior open shoulder surgery
  * Concomitant latissimus dorsi transfer
  * Patients not undergoing a standard of care physical therapy protocol
  * Pregnant, patient-reported
  * Cognitively impaired

Answer: D