TrialPanorama/Dataset huggingface dataset:
Please select the outcome measures that correspond to the clinical trial below.
Title: Pilot Test of Patient Decision Aid for Medication-Assisted Treatment for Opioid Use Disorder
Brief Summary: The aims of the current study phase (R21) are: Aim 1. Develop a patient decision aid (PtDA-MAT) by incorporating best available scientific evidence on MAT as well as feedback from patients and clinical providers related to clinical priorities, perceived utility, and acceptability; Aim 2. Conduct pilot testing of the PtDA-MAT in an iterative process guided by an expert panel and involving key stakeholders (e.g., patients, physicians, policymakers) and field-testing.


Options:
A: Treatment Retention (3 months)
B: Recruitment Rate (Up to one year from when the study starts enrolling participants)
C: PTSD Symptoms (Post-treatment, ten weeks); Depression Symptoms (Measured at Post-Treatment, at 10 weeks); State Anxiety (Measured at Post-Treatment, at 10 weeks)
D: Mean Heinrichs-Carpenter Quality of Life Scale Scores Over Time (Baseline, Month 6, month 12, month 18 and month 24)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Phase II Trial of Vaccination with Lysate-loaded, Mature Dendritic Cells Integrated Into Standard Radiochemotherapy in Newly Diagnosed Glioblastoma
Brief Summary: The primary objective of the study is to determine whether overall survival of newly diagnosed glioblastoma patients treated with lysate-loaded, mature dendritic cell vaccines as add-on to the standard of care consisting of resection, radiotherapy with concomitant temozolomide chemotherapy and subsequent adjuvant temozolomide chemotherapy is superior to the treatment with the standard of care alone.


Options:
A: Evaluation of the treatment impact on progression-free survival (5 years)
B: Median Overall Survival Time (From randomization to last follow-up. Maximum follow-up at time of analysis was 4.4 years.)
C: Overall survival (OS) (Day of surgery until death of any cause assessed up to 34 months)
D: Overall Survival (During treatment and every three months from end of treatment through end of study or approximately up to 5 years.)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: The Videolaryngoscopy in Small Infants (VISI) Trial
Brief Summary: Complications related to infant (≤ 1 year) airway management are under-appreciated because of few rigorous and targeted studies. Investigators have recently shown that multiple tracheal intubation (TI) attempts are a key risk factor for intubation-related complications in small children. Tracheal Intubation using Video laryngoscopy (VL) has become popular in anesthesiology practice because of several advantages over conventional direct laryngoscopy (DL). Studies show that VL improves the view of the airway compared to DL, requires fewer intubation attempts, but may take more time to intubate the trachea. This study compares first attempt success of VL to DL in infants presenting for elective surgery.


Options:
A: Endotracheal intubation success rate. (5 minutes)
B: Time to Intubation (Assessed intraoperatively at time of intubation)
C: Number of Participants With Success in the First Attempt (at the time of intubation)
D: Success rate (5 minutes)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: The Artificial Kidney Initiation in Kidney Injury 2 A Multi-Centre, Randomized, Controlled Trial
Brief Summary: The timing of renal replacement therapy (RRT) in the context of severe acute kidney injury (AKI) is one the most debated issues in critical care medicine. The Artificial Kidney Initiation in Kidney Injury (AKIKI) was the first large prospective multicenter randomized trial published on this topic. This study (published in the New England Journal of Medicine, July 2017) showed no significant difference between an early and delayed RRT initiation strategy in term of mortality. Nearly 50% of patients escaped RRT in the delayed strategy and this strategy was associated with less catheter-related infections and faster renal function recovery. Two (serum urea concentration \>40 mmol/l and oliguria/anuria for more than 72 hours) of the 5 criteria which mandated RRT in the delayed strategy are still open to debate since they have never been shown to put patient at danger. To go further into our investigation of RRT criteria, the investigators designed a study that would compare the "delayed strategy" used in AKIKI that can now be considered as "standard" with another in which RRT is delayed for a longer period in the absence of a life-threatening complication (such as hyperkalemia or severe overload pulmonary edema).


Options:
A: number of RRT-free days (Day 28 after randomization)
B: Death from all causes at 30 days after randomisation (30 days)
C: Renal replacement therapy proportion (28 days)
D: Feasibility of protocol adherence (14 days)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Effect of Vaginal Douching With Betadine Versus Non Douching Before CS for Prevention of Post Operative Infections
Brief Summary: The present study was a prospective randomized controlled trial in which subjects received a vaginal preparation with povidone-iodine solution immediately prior to caesarean delivery or received no vaginal preparation


Options:
A: Number of cases of endometritis after cesarean section (15 days)
B: Postpartum endometritis (6 weeks after Cesarean section)
C: Surgical site infection (30 days)
D: Composite Postoperative Infectious Morbidity (30 days postoperatively)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Motor Control Exercise and Patient Education for the Management of Chronic Low Back Pain in a Low-Resource Rural Nigerian Community: A Pilot Randomized Controlled Trial.
Brief Summary: The main purpose of this pilot single-blind randomized clinical trial is to assess the feasibility of implementing motor control exercise and patient education for the management of chronic low back pain (CLBP) in a low resource rural Nigerian community.


Options:
A: Change from Baseline in Average Pain intensity in previous week (12 wks); Change from Baseline in Modified Roland Morris questionnaire for Back pain specific disability (12 wks)
B: Change of self-reported pain on 100mm Visual Analogue Scale (VAS) (Baseline (-4 days); Pre-Test (0 days); Post-Test (+25 days) and follow-up (+45 days)); Change of functional status recorded with the Oswestry Disability Index (ODI) (Baseline (-4 days); Pre-Test (0 days); Post-Test (+25 days) and follow-up (+45 days))
C: Change in pain Intensity (Baseline and 6 weeks after beginning treatment.); Change in functional disability (Baseline and 6 weeks after beginning treatment.)
D: Pain Intensity (2 months after randomisation); Disability (2 months after randomisation)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Efficacy of Ultrasound-Guided Erector Spinae Plan Block on Postoperative Pain After Laparoscopic Cholecystectomy Under General Anesthesia. Randomized, Controlled Trial
Brief Summary: Laparoscopic cholecystectomy is a widely employed procedure in ambulatory surgery. Pain after laparoscopic cholecystectomy arises significantly from port site incisions in the anterior abdominal wall. Innervation of the anterior abdominal wall is segmentally supplied by pain afferents in the plane of fascia between transversus abdominis and the internal oblique muscles. Opioids analgesia is used to control postoperative pain, but it carries the risk of increased nausea and vomiting, ileus and sedation that may delay hospital discharge.

Several techniques have been tried as.neuroaxial narcotics, intraperitoneal lavage of local anesthetic and transversus abdominis plan (TAP) block and successfully reduced opioid use and improve postoperative analgesia.

The ultrasound-guided erector spinae plan(ESP) block is a recently described technique which produces reliable unilateral analgesia at thoraco-lumbar dermatomes. ESP block carries the advantages of being simple, safe, easily recognizable by ultrasound, and a catheter can be threaded to extend the duration of analgesia.

Few case series reported the efficacy of (US)-guided ESP blocks in reducing postoperative pain and opioids consumption.

Because of that, the investigators aimed to test the hypothesis that US-guided ESP blocks can decrease opioid consumption during the first 24 h after of laparoscopic cholecystectomy in comparison with the conventional systemic analgesia.


Options:
A: Opioid consumption (Change from baseline opioid consumption at postoperative 1, 2, 4, 8, 16, 24 and 48 hours)
B: Visual analogue score (24 hours); Total morphine consumption (24 hours); First time to receive morphine (24 hours)
C: Morphine consumption (24 hour postoperatively)
D: Morphine consumption (24 hours postoperatively.)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Efficacy of Ultrasound-Guided Erector Spinae Plan Block on Postoperative Pain After Laparoscopic Cholecystectomy Under General Anesthesia. Randomized, Controlled Trial
Brief Summary: Laparoscopic cholecystectomy is a widely employed procedure in ambulatory surgery. Pain after laparoscopic cholecystectomy arises significantly from port site incisions in the anterior abdominal wall. Innervation of the anterior abdominal wall is segmentally supplied by pain afferents in the plane of fascia between transversus abdominis and the internal oblique muscles. Opioids analgesia is used to control postoperative pain, but it carries the risk of increased nausea and vomiting, ileus and sedation that may delay hospital discharge.

Several techniques have been tried as.neuroaxial narcotics, intraperitoneal lavage of local anesthetic and transversus abdominis plan (TAP) block and successfully reduced opioid use and improve postoperative analgesia.

The ultrasound-guided erector spinae plan(ESP) block is a recently described technique which produces reliable unilateral analgesia at thoraco-lumbar dermatomes. ESP block carries the advantages of being simple, safe, easily recognizable by ultrasound, and a catheter can be threaded to extend the duration of analgesia.

Few case series reported the efficacy of (US)-guided ESP blocks in reducing postoperative pain and opioids consumption.

Because of that, the investigators aimed to test the hypothesis that US-guided ESP blocks can decrease opioid consumption during the first 24 h after of laparoscopic cholecystectomy in comparison with the conventional systemic analgesia.


Options:
A: Morphine consumption (24 hours postoperatively.)
B: Morphine consumption (postoperative first 24 hour)
C: pain score 3 hours postoperatively (3 hours after surgery); pain score 6 hours postoperatively (6 hours after surgery); pain score 12 hours postoperatively (12 hours after surgery); pain score 24 hours postoperatively (24 hours after surgery); pain score on arrival to Post-Anesthesia Care Unit (PACU) (immediately postoperatively); pain score at discharge from Post-Anesthesia Care Unit (PACU), ranging from 0 to 10, where 0 means "no pain" and 10 means "worst pain imaginable" (immediately postoperatively)
D: Pain scores (1st, 2nd, 4th, 8th, 16th, 24th and 48th hours after surgery)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: m-Health to Increase Service Utilization in Recently Incarcerated Homeless Adults
Brief Summary: There is a significant revolving door of incarceration among homeless adults, a population with substantial health disparities. Homeless adults who receive the professional coordination of individualized care (i.e., case management) during the period following their release from jail experience fewer mental health and substance use problems, are more likely to obtain stable housing, and are less likely to be re-incarcerated. The proposed study will use mobile technology to address these barriers and fill gaps in the understanding of the causes of the revolving door of homeless incarceration. This research represents a step toward integrated service connection and healthcare service provision for one of the most underserved, high need, and understudied populations in the United States. Smart phone apps that increase the use of available healthcare services and identify predictors of key outcomes (e.g., homelessness, re-arrest, medication compliance) could be used to reach hard to reach populations with histories of significant and persistent health disparities (e.g., homeless adults).


Options:
A: Number of Case Management Sessions Completed (6-month follow-up)
B: Treatment Progress (6 months)
C: Discussion-opportunity about risk of partner abuse during physician-patient medical encounter (audiotaped data); Detection of partner abuse during physician-patient medical encounter (audio taped data)
D: Three consecutive weeks of negative urine tests (benzoyl ecgonine) for cocaine use (no slips allowed). (These must be the last three weeks (7,8,9) of the trial.)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: A Phase 3 Randomized, Double-blind, Active-controlled, Parallel-group, Multi-center Study in Hemodialysis Participants With Anemia of Chronic Kidney Disease to Evaluate the Efficacy, Safety and Pharmacokinetics of Three-times Weekly Dosing of Daprodustat Compared to Recombinant Human Erythropoietin, Following a Switch From Recombinant Human Erythropoietin or Its Analogs
Brief Summary: This Phase 3 study in hemodialysis-dependent subjects with anemia will evaluate the efficacy and safety of daprodustat administered three-times weekly compared to epoetin alfa, the current standard of care. This study includes a 4 week Screening Period, a 52 week Treatment Period and a 4 to 6 week follow-up period. Each subject will remain in the study for up to 62 weeks. Approximately 402 subjects will be randomized to receive either daprodustat three times weekly or epoetin alfa three-times weekly or once weekly, depending on dose level.


Options:
A: Mean Hemoglobin (Hgb) During the Primary Efficacy Evaluation Period (Weeks 40 to 52) (Weeks 40 to 52)
B: Mean Change From Baseline in Hemoglobin (Hgb) During Evaluation Period (Week 28 to Week 52) (Baseline (Pre-dose on Day 1) and evaluation period (Week 28 to Week 52))
C: Change in local laboratory hemoglobin level from baseline to the average during the last 4 weeks treatment period (Baseline and weeks 14 to 17)
D: Mean Change From Baseline in Hemoglobin Levels Over the Evaluation Period (Week 28 to Week 52) (Baseline (Pre-dose on Day 1) and evaluation period (Week 28 to Week 52))

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Effects of Congruent and In-congruent Experiential Learning on Intake of a Novel Vegetable in Preschool Children
Brief Summary: The aim of this cluster randomized control trial is to test the efficacy of providing experience of a target novel vegetable within the context of an interactive story time to increase intake of the target novel vegetable in preschool aged children (aged 2-5 years).


Options:
A: Change in self-reported nutrition practices (baseline, post 3-months, post 12-months)
B: Body mass index (2005, 2006, 2007, 2008); nutrition behavior (2005, 2006, 2007, 2008); physical activity (2005, 2006, 2007, 2008)
C: Change in EPAO-SR Scores from Baseline to Post-intervention (Measures collected at baseline (2-4 weeks prior to the intervention) and post-intervention (1-3 weeks following the intervention))
D: Change in intake of the target vegetable (Change in intake of the target vegetable from Baseline to day 14)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Effects of Congruent and In-congruent Experiential Learning on Intake of a Novel Vegetable in Preschool Children
Brief Summary: The aim of this cluster randomized control trial is to test the efficacy of providing experience of a target novel vegetable within the context of an interactive story time to increase intake of the target novel vegetable in preschool aged children (aged 2-5 years).


Options:
A: 1-year, and 3-year changes from baseline in questionaires scores for knowledge, attitudes, and habits of children, parents and teachers in regards to a healthy lifestyle. (3 years)
B: Change in intake of the target vegetable (Change in intake of the target vegetable from Baseline to day 14)
C: Fruit and Vegetable Consumption, servings per week (3 weeks); Perceived Behavioral Control scale score (3 weeks); Attitudes scale score (3 weeks); Intrinsic Motivation scale score (3 weeks); Fruit and vegetable consumption, servings per week (5 weeks); Perceived Behavioral Control scale score (5 weeks); Attitudes scale score (5 weeks); Intrinsic Motivation scale score (5 weeks)
D: Change from baseline in energy dense food consumption at 12 months (12 months); Change from baseline in nutrient dense food consumption at 12 months (12 months)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Effects of Congruent and In-congruent Experiential Learning on Intake of a Novel Vegetable in Preschool Children
Brief Summary: The aim of this cluster randomized control trial is to test the efficacy of providing experience of a target novel vegetable within the context of an interactive story time to increase intake of the target novel vegetable in preschool aged children (aged 2-5 years).


Options:
A: Change in children's Knowledge, attitude, habit (KAH) scores (baseline and 5 months)
B: Change in intake of the target vegetable (Change in intake of the target vegetable from Baseline to day 14)
C: BMI and aerobic fitness (1 schoolyear)
D: Change of BMI Z-score for preschoolers (Baseline to 6 month (Midline) Follow-up or 1 year (Post Intervention) Follow-up)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Effects of Congruent and In-congruent Experiential Learning on Intake of a Novel Vegetable in Preschool Children
Brief Summary: The aim of this cluster randomized control trial is to test the efficacy of providing experience of a target novel vegetable within the context of an interactive story time to increase intake of the target novel vegetable in preschool aged children (aged 2-5 years).


Options:
A: Change in EPAO-SR Scores from Baseline to Post-intervention (Measures collected at baseline (2-4 weeks prior to the intervention) and post-intervention (1-3 weeks following the intervention))
B: Change in intake of the target vegetable (Change in intake of the target vegetable from Baseline to day 14)
C: Change in Percentage of Children Meeting Physical Activity Policy (Spring of Year 1, Year 2, and Year 3)
D: N/A

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Effect of Banning Menthol Flavorant on Cigarette and E-Cigarette Use
Brief Summary: In this pilot study, menthol cigarette smokers will be randomized to one of three experimental marketplaces: 1) a condition simulating a ban on menthol cigarettes but not menthol e-cigarettes (condition A); 2) a condition simulating a ban on both menthol cigarettes and menthol e-cigarettes (Condition B); and 3) a condition in which menthol is not banned for either product (Condition C - the control condition). All conditions would have medicinal nicotine available if subjects decide to quit tobacco products entirely. At visits occurring every two weeks over a 6 week period, subjects will receive "credits" that they could exchange for any product available in their randomized marketplace condition. Outcomes include the amount of each tobacco product used.


Options:
A: Amount of Tobacco Product Used (6 weeks)
B: Continuous smoking abstinence (1) (6 months post quit date)
C: smoking cessation (52 weeks)
D: Number of Participants Completing Continuous Four-week Abstinence From Smoking Between the 8-week and 11-week Post Quit Day Visits (Period between 8-week and 11-week visits post target Quit Day)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Effect of Banning Menthol Flavorant on Cigarette and E-Cigarette Use
Brief Summary: In this pilot study, menthol cigarette smokers will be randomized to one of three experimental marketplaces: 1) a condition simulating a ban on menthol cigarettes but not menthol e-cigarettes (condition A); 2) a condition simulating a ban on both menthol cigarettes and menthol e-cigarettes (Condition B); and 3) a condition in which menthol is not banned for either product (Condition C - the control condition). All conditions would have medicinal nicotine available if subjects decide to quit tobacco products entirely. At visits occurring every two weeks over a 6 week period, subjects will receive "credits" that they could exchange for any product available in their randomized marketplace condition. Outcomes include the amount of each tobacco product used.


Options:
A: Amount of Tobacco Product Used (6 weeks)
B: 7-day Point Prevalence All Tobacco Abstinence (12 weeks - end of treatment)
C: Change in pulmonary health (dry cough, breath shortness, mouth irritation) index (baseline, 6 months, 12 months)
D: Change in sputum eosinophile-% from >1% to normal or neutrophile-% from >61% to normal, from baseline (week 0) to week 12. (Time frame for primary outcome: 0-12 weeks (total study duration 24 weeks))

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: EFFICACY OF MOBILE PHONE REMINDERS (AND PHOTOVOICE) IN IMPROVING CHILDHOOD IMMUNIZATION UPTAKE AND REDUCING INCIDENCE OF VACCINE-PREVENTABLE DISEASES - A RANDOMIZED CONTROLLED TRIAL AMONG POSTPARTUM MOTHERS AND CAREGIVERS IN NIGERIA
Brief Summary: This study aims to implement and test the efficacy of photovoice, Short Messaging Service (SMS) and phone call reminders in improving childhood immunization coverage (uptake, timeliness and completion rates) and reducing incidence of vaccine-preventable diseases (VPDs) among infants in Nigeria


Options:
A: Change in Exclusive Breastfeeding Rate (2 weeks after birth); Change in Exclusive Breastfeeding Rate (3 months after birth); Change in Exclusive Breastfeeding Rate (6 months after birth)
B: Immunization coverage (12 months); Timeliness of receipt of scheduled immunization (12 months)
C: Viral load (6 months post-randomization)
D: Acceptability of at least one method of effective contraception (4 months)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: EFFICACY OF MOBILE PHONE REMINDERS (AND PHOTOVOICE) IN IMPROVING CHILDHOOD IMMUNIZATION UPTAKE AND REDUCING INCIDENCE OF VACCINE-PREVENTABLE DISEASES - A RANDOMIZED CONTROLLED TRIAL AMONG POSTPARTUM MOTHERS AND CAREGIVERS IN NIGERIA
Brief Summary: This study aims to implement and test the efficacy of photovoice, Short Messaging Service (SMS) and phone call reminders in improving childhood immunization coverage (uptake, timeliness and completion rates) and reducing incidence of vaccine-preventable diseases (VPDs) among infants in Nigeria


Options:
A: Viral load (6 months post-randomization)
B: Immunization coverage (12 months); Timeliness of receipt of scheduled immunization (12 months)
C: Count of Women Who Have Excess Gestational Weight Gain (Approximately 6 months (from 10-13 weeks gestation to 35-36 weeks gestation))
D: The Number of Condomless Sex Acts at 3-months Post-intervention (3-months post-intervention); Percent of Boys Reporting Abstinence at 3-months Post-intervention (3-months post-intervention)

Answer: B