Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Impact of Dietary Flavanols on Vascular Health in a General Population of Healthy Middle-aged Europeans: a Randomized Controlled Study
Brief Summary: Atherosclerosis progressively occurs with increasing age in the general population. So far most dietary intervention studies with flavanols were performed over short time frames and in small groups of young healthy and older patients with manifest cardiovascular disease, respectively. Vascular health is defined as absence of vascular disease and the presence of optimal parameters that determine the development and progression of arteriosclerosis (endothelial function, blood pressure, plasma lipids, and glucose). It is not clear whether flavanols can improve parameters of vascular health, most importantly endothelial function, when given repetitively to healthy middle aged and which factors affect the efficacy of flavanol interventions.


Options:
A: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Nestlé Noir intense 40 grx2 | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Nestlé Placebo Chocolate 40 grx2 | Intervention Type: DIETARY_SUPPLEMENT; Name: Nestlé Noir intense 40 grx2; Assigned to Arm(s): 1 | Intervention Type: DIETARY_SUPPLEMENT; Name: Nestlé Placebo Chocolate 40 grx2; Assigned to Arm(s): 2
B: Arm Label: flavanol rich intervention; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Flavanol (410 mg) | Arm Label: flavanol free intervention; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Control (no flavanols) | Intervention Type: DIETARY_SUPPLEMENT; Name: Flavanol (410 mg); Assigned to Arm(s): flavanol rich intervention | Intervention Type: DIETARY_SUPPLEMENT; Name: Control (no flavanols); Assigned to Arm(s): flavanol free intervention
C: Arm Label: flavanol rich intervention; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Flavanol rich intervention | Arm Label: flavanol free intervention; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Flavanol free control | Intervention Type: DIETARY_SUPPLEMENT; Name: Flavanol rich intervention; Assigned to Arm(s): flavanol rich intervention | Intervention Type: DIETARY_SUPPLEMENT; Name: Flavanol free control; Assigned to Arm(s): flavanol free intervention
D: Arm Label: Theobromine drink; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Theobromine | Arm Label: Cocoa drink; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Cocoa | Arm Label: Placebo drink; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Placebo | Arm Label: Cocoa and theobromine drink; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Cocoa and theobromine | Intervention Type: DIETARY_SUPPLEMENT; Name: Theobromine; Assigned to Arm(s): Theobromine drink | Intervention Type: DIETARY_SUPPLEMENT; Name: Cocoa; Assigned to Arm(s): Cocoa drink | Intervention Type: DIETARY_SUPPLEMENT; Name: Cocoa and theobromine; Assigned to Arm(s): Cocoa and theobromine drink | Intervention Type: DIETARY_SUPPLEMENT; Name: Placebo; Assigned to Arm(s): Placebo drink

Answer: B