Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Multi-center, Randomized, 12-week Treatment, Doubleblind Study to Assess the Efficacy and Safety of QMF149 (150/80 Microgram) Compared With MF Twisthaler® (200 Microgram) in Adult and Adolescent Patients With Asthma
Brief Summary: The purpose of the trial was to evaluate efficacy and safety of QMF149 150/80 microgram o.d.

delivered via Concept1 compared to MF 200 microgram o.d., delivered via Twisthaler® in terms of lung function and symptom control in poorly (ie inadequately) controlled asthma patients. This study was to assess contribution of LABA as an add-on therapy to low dose ICS monotherapy.


Options:
A: Arm Label: FF/UMEC/VI (100/31.25/25) mcg closed triple therapy; Type: EXPERIMENTAL; Interventions: Drug: FF/UMEC/VI (100/31.25/25) mcg, Drug: FF/VI (100/25) mcg, Drug: Fluticasone/salmeterol (FSC), Drug: Albuterol/salbutamol, Device: ELLIPTA DPI, Device: DISKUS DPI, Device: METERED-DOSE INHALER (MDI) | Arm Label: FF/UMEC/VI (100/62.5/25) mcg closed triple therapy; Type: EXPERIMENTAL; Interventions: Drug: FF/UMEC/VI (100/62.5/25) mcg, Drug: FF/VI (100/25) mcg, Drug: Fluticasone/salmeterol (FSC), Drug: Albuterol/salbutamol, Device: ELLIPTA DPI, Device: DISKUS DPI, Device: METERED-DOSE INHALER (MDI) | Arm Label: FF/UMEC/VI (200/31.25/25) mcg closed triple therapy; Type: EXPERIMENTAL; Interventions: Drug: FF/UMEC/VI (200/31.25/25) mcg, Drug: FF/VI (100/25) mcg, Drug: Fluticasone/salmeterol (FSC), Drug: Albuterol/salbutamol, Device: ELLIPTA DPI, Device: DISKUS DPI, Device: METERED-DOSE INHALER (MDI) | Arm Label: FF/UMEC/VI (200/62.5/25) mcg closed triple therapy; Type: EXPERIMENTAL; Interventions: Drug: FF/UMEC/VI (200/62.5/25) mcg, Drug: FF/VI (100/25) mcg, Drug: Fluticasone/salmeterol (FSC), Drug: Albuterol/salbutamol, Device: ELLIPTA DPI, Device: DISKUS DPI, Device: METERED-DOSE INHALER (MDI) | Arm Label: FF/VI (100/25) mcg dual combination therapy; Type: ACTIVE_COMPARATOR; Interventions: Drug: FF/VI (100/25) mcg, Drug: Fluticasone/salmeterol (FSC), Drug: Albuterol/salbutamol, Device: ELLIPTA DPI, Device: DISKUS DPI, Device: METERED-DOSE INHALER (MDI) | Arm Label: FF/VI (200/25) mcg dual combination therapy; Type: ACTIVE_COMPARATOR; Interventions: Drug: FF/VI (100/25) mcg, Drug: FF/VI (200/25) mcg, Drug: Fluticasone/salmeterol (FSC), Drug: Albuterol/salbutamol, Device: ELLIPTA DPI, Device: DISKUS DPI, Device: METERED-DOSE INHALER (MDI) | Intervention Type: DRUG; Name: FF/UMEC/VI (100/31.25/25) mcg; Assigned to Arm(s): FF/UMEC/VI (100/31.25/25) mcg closed triple therapy | Intervention Type: DRUG; Name: FF/UMEC/VI (100/62.5/25) mcg; Assigned to Arm(s): FF/UMEC/VI (100/62.5/25) mcg closed triple therapy | Intervention Type: DRUG; Name: FF/UMEC/VI (200/31.25/25) mcg; Assigned to Arm(s): FF/UMEC/VI (200/31.25/25) mcg closed triple therapy | Intervention Type: DRUG; Name: FF/UMEC/VI (200/62.5/25) mcg; Assigned to Arm(s): FF/UMEC/VI (200/62.5/25) mcg closed triple therapy | Intervention Type: DRUG; Name: FF/VI (100/25) mcg; Assigned to Arm(s): FF/UMEC/VI (100/31.25/25) mcg closed triple therapy, FF/UMEC/VI (100/62.5/25) mcg closed triple therapy, FF/UMEC/VI (200/31.25/25) mcg closed triple therapy, FF/UMEC/VI (200/62.5/25) mcg closed triple therapy, FF/VI (100/25) mcg dual combination therapy, FF/VI (200/25) mcg dual combination therapy | Intervention Type: DRUG; Name: FF/VI (200/25) mcg; Assigned to Arm(s): FF/VI (200/25) mcg dual combination therapy | Intervention Type: DRUG; Name: Fluticasone/salmeterol (FSC); Assigned to Arm(s): FF/UMEC/VI (100/31.25/25) mcg closed triple therapy, FF/UMEC/VI (100/62.5/25) mcg closed triple therapy, FF/UMEC/VI (200/31.25/25) mcg closed triple therapy, FF/UMEC/VI (200/62.5/25) mcg closed triple therapy, FF/VI (100/25) mcg dual combination therapy, FF/VI (200/25) mcg dual combination therapy | Intervention Type: DRUG; Name: Albuterol/salbutamol; Assigned to Arm(s): FF/UMEC/VI (100/31.25/25) mcg closed triple therapy, FF/UMEC/VI (100/62.5/25) mcg closed triple therapy, FF/UMEC/VI (200/31.25/25) mcg closed triple therapy, FF/UMEC/VI (200/62.5/25) mcg closed triple therapy, FF/VI (100/25) mcg dual combination therapy, FF/VI (200/25) mcg dual combination therapy | Intervention Type: DEVICE; Name: ELLIPTA DPI; Assigned to Arm(s): FF/UMEC/VI (100/31.25/25) mcg closed triple therapy, FF/UMEC/VI (100/62.5/25) mcg closed triple therapy, FF/UMEC/VI (200/31.25/25) mcg closed triple therapy, FF/UMEC/VI (200/62.5/25) mcg closed triple therapy, FF/VI (100/25) mcg dual combination therapy, FF/VI (200/25) mcg dual combination therapy | Intervention Type: DEVICE; Name: DISKUS DPI; Assigned to Arm(s): FF/UMEC/VI (100/31.25/25) mcg closed triple therapy, FF/UMEC/VI (100/62.5/25) mcg closed triple therapy, FF/UMEC/VI (200/31.25/25) mcg closed triple therapy, FF/UMEC/VI (200/62.5/25) mcg closed triple therapy, FF/VI (100/25) mcg dual combination therapy, FF/VI (200/25) mcg dual combination therapy | Intervention Type: DEVICE; Name: METERED-DOSE INHALER (MDI); Assigned to Arm(s): FF/UMEC/VI (100/31.25/25) mcg closed triple therapy, FF/UMEC/VI (100/62.5/25) mcg closed triple therapy, FF/UMEC/VI (200/31.25/25) mcg closed triple therapy, FF/UMEC/VI (200/62.5/25) mcg closed triple therapy, FF/VI (100/25) mcg dual combination therapy, FF/VI (200/25) mcg dual combination therapy
B: Arm Label: QMF149 150/80 μg; Type: EXPERIMENTAL; Interventions: Drug: QMF149 150/80 μg | Arm Label: MF 200 µg; Type: ACTIVE_COMPARATOR; Interventions: Drug: MF 200 μg | Intervention Type: DRUG; Name: QMF149 150/80 μg; Assigned to Arm(s): QMF149 150/80 μg | Intervention Type: DRUG; Name: MF 200 μg; Assigned to Arm(s): MF 200 µg
C: Arm Label: Fluticasone/ Formoterol (Flutiform); Type: EXPERIMENTAL; Interventions: Drug: Fluticasone/ Formoterol | Arm Label: Fluticasone/ salmeterol (Seretide); Type: ACTIVE_COMPARATOR; Interventions: Drug: fluticasone/ salmeterol | Intervention Type: DRUG; Name: Fluticasone/ Formoterol; Assigned to Arm(s): Fluticasone/ Formoterol (Flutiform) | Intervention Type: DRUG; Name: fluticasone/ salmeterol; Assigned to Arm(s): Fluticasone/ salmeterol (Seretide)
D: Arm Label: Fluticasone Furoate (FF); Type: ACTIVE_COMPARATOR; Interventions: Drug: FF | Arm Label: Fluticasone Furoate /Vilanterol (VI); Type: ACTIVE_COMPARATOR; Interventions: Drug: FF/VI | Arm Label: Fluticasone Furoate/GSK573719; Type: EXPERIMENTAL; Interventions: Drug: FF/GSK573719 | Intervention Type: DRUG; Name: FF/GSK573719; Assigned to Arm(s): Fluticasone Furoate/GSK573719 | Intervention Type: DRUG; Name: FF/GSK573719; Assigned to Arm(s): Fluticasone Furoate/GSK573719 | Intervention Type: DRUG; Name: FF/GSK573719; Assigned to Arm(s): Fluticasone Furoate/GSK573719 | Intervention Type: DRUG; Name: FF/GSK573719; Assigned to Arm(s): Fluticasone Furoate/GSK573719 | Intervention Type: DRUG; Name: FF/GSK573719; Assigned to Arm(s): Fluticasone Furoate/GSK573719 | Intervention Type: DRUG; Name: FF; Assigned to Arm(s): Fluticasone Furoate (FF) | Intervention Type: DRUG; Name: FF/VI; Assigned to Arm(s): Fluticasone Furoate /Vilanterol (VI)

Answer: B