Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Direct Current Stimulation Versus Sham for Treatment of Fibromyalgia: a Double Blinded Randomized Controlled Trial
Brief Summary: The aim of this study is to assess the effectiveness of transcranial direct current stimulation (tDCS) in treating fibromyalgia.

Participants will be randomly assigned to one of the two groups: Group I (Intervention group) tDCS (2mA for 25 minutes on 5 consecutive days/week for 2 weeks with the anode centered over M1 bilaterally Anodal tDCS for 20 minutes at 1.5 mA (15 s ramp in and 15 s ramp out) will be applied daily for 10 consecutive days (5 sessions/week) . The anodal electrode (24 cm² with current density of 0.08 mA (2mA/24 cm²) will be placed over the left primary motor area in group I, and the reference electrode (24 cm² will be fixed over the contralateral arm (extracephalic).

Daily tDCS was given to prolong and stabilize these long-lasting after-effects. Group II will receive sham tDCS will be applied using the above described parameters in group I. For sham tDCS, the placement of the electrodes, current intensity, and ramp time was identical to real tDCS stimulation group; however, the stimulation lasted only for 30 Sec. However, since none of the patients have been experienced tDCS previously, they were unaware of which stimulation is real and which sham is. The investigator responsible for delivering tDCS had no contact with the patients. All study participants will be followed up by the same evaluation sheet and by an evaluator who are blinded to the type of intervention she /he has received.Evaluation will be done pre assessment, post 5 sessions, post 10 sessions, post one month and post 2 months by using wide spread pain index (WPI) \& symptoms severity of fibromyalgia, measuring visual analogue scale (VAS), Depression and anxiety will be assessed using Hamilton Depression Scale (HDS) and anxiety scale, pain sensitivity threshold by using Electronic Von Frey unit EVF4 . Determination of human beta-endorphin level before start sessions and after end 10 sessions.


Options:
A: Arm Label: Active tDCS; Type: EXPERIMENTAL; Interventions: Device: Active tDCS | Arm Label: Sham tDCS; Type: SHAM_COMPARATOR; Interventions: Device: Sham tDCS | Intervention Type: DEVICE; Name: Active tDCS; Assigned to Arm(s): Active tDCS | Intervention Type: DEVICE; Name: Sham tDCS; Assigned to Arm(s): Sham tDCS
B: Arm Label: Group I; Type: ACTIVE_COMPARATOR; Interventions: Device: Real tDCS | Arm Label: Group II; Type: SHAM_COMPARATOR; Interventions: Device: Sham tDCS | Intervention Type: DEVICE; Name: Real tDCS; Assigned to Arm(s): Group I | Intervention Type: DEVICE; Name: Sham tDCS; Assigned to Arm(s): Group II
C: Arm Label: 1; Type: PLACEBO_COMPARATOR; Interventions: Other: Transcranial stimulation | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Other: Transcranial stimulation | Intervention Type: OTHER; Name: Transcranial stimulation; Assigned to Arm(s): 1 | Intervention Type: OTHER; Name: Transcranial stimulation; Assigned to Arm(s): 2
D: Arm Label: Both Sham rTMS and Neuroacupuncture; Type: SHAM_COMPARATOR; Interventions: Device: Sham rTMS, Device: Sham Neuroacupuncture | Arm Label: Active rTMS and sham Neuroacupuncture; Type: SHAM_COMPARATOR; Interventions: Device: Active rTMS, Device: Sham Neuroacupuncture | Arm Label: Sham rTMS and Active Neuroacupuncture; Type: SHAM_COMPARATOR; Interventions: Device: Sham rTMS, Device: Active Neuroacupuncture | Arm Label: Both Active rTMS and Neuroacupuncture; Type: ACTIVE_COMPARATOR; Interventions: Device: Active rTMS, Device: Active Neuroacupuncture | Intervention Type: DEVICE; Name: Active rTMS; Assigned to Arm(s): Active rTMS and sham Neuroacupuncture, Both Active rTMS and Neuroacupuncture | Intervention Type: DEVICE; Name: Sham rTMS; Assigned to Arm(s): Both Sham rTMS and Neuroacupuncture, Sham rTMS and Active Neuroacupuncture | Intervention Type: DEVICE; Name: Active Neuroacupuncture; Assigned to Arm(s): Both Active rTMS and Neuroacupuncture, Sham rTMS and Active Neuroacupuncture | Intervention Type: DEVICE; Name: Sham Neuroacupuncture; Assigned to Arm(s): Active rTMS and sham Neuroacupuncture, Both Sham rTMS and Neuroacupuncture

Answer: B