Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Primaquine's Gametocytocidal Efficacy in Malaria Asymptomatic Carriers Treated With Dihydroartemisinin-piperaquine in The Gambia
Brief Summary: In this study, the investigators are interested to know if lower doses of Primaquine together with dihydroartemisinin-piperaquine can produce a similar effect of clearing both sexual and asexual parasites in asymptomatic carriers compared to the recommended dose of primaquine but with a decreased risk of haemolysis.

Children (\> 1 year) and adults with normal Glucose-6-phosphate dehydrogenase enzyme levels but with asexual Plasmodium falciparum parasites on the day of screening will be invited to take part in this study.


Options:
A: Arm Label: artemether-lumefantrine+placebo; Type: ACTIVE_COMPARATOR; Interventions: Drug: Placebo (For artemether-lumefantrine arm) | Arm Label: artemether-lumefantrine+primaquine; Type: EXPERIMENTAL; Interventions: Drug: Primaquine (For artemether-lumefantrine+primaquine arm) | Intervention Type: DRUG; Name: Primaquine (For artemether-lumefantrine+primaquine arm); Assigned to Arm(s): artemether-lumefantrine+primaquine | Intervention Type: DRUG; Name: Placebo (For artemether-lumefantrine arm); Assigned to Arm(s): artemether-lumefantrine+placebo
B: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Drug: sulfadoxine-pyrimethamine (SP) plus artesunate (AS) | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Drug: primaquine (PQ) plus SP+AS | Intervention Type: DRUG; Name: sulfadoxine-pyrimethamine (SP) plus artesunate (AS); Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: primaquine (PQ) plus SP+AS; Assigned to Arm(s): 2
C: Arm Label: Eurartesim (control); Type: OTHER; Interventions: Drug: DHA-PPQ | Arm Label: Primaquine 0.75mg base/kg; Type: EXPERIMENTAL; Interventions: Drug: DHA-PPQ, Drug: PQ (0.75) | Arm Label: Primaquine 0.4mg base /kg; Type: EXPERIMENTAL; Interventions: Drug: DHA-PPQ, Drug: PQ (0.4) | Arm Label: Primaquine 0.2mg base/kg; Type: EXPERIMENTAL; Interventions: Drug: DHA-PPQ, Drug: PQ (0.2) | Intervention Type: DRUG; Name: DHA-PPQ; Assigned to Arm(s): Eurartesim (control), Primaquine 0.2mg base/kg, Primaquine 0.4mg base /kg, Primaquine 0.75mg base/kg | Intervention Type: DRUG; Name: PQ (0.75); Assigned to Arm(s): Primaquine 0.75mg base/kg | Intervention Type: DRUG; Name: PQ (0.4); Assigned to Arm(s): Primaquine 0.4mg base /kg | Intervention Type: DRUG; Name: PQ (0.2); Assigned to Arm(s): Primaquine 0.2mg base/kg
D: Arm Label: dihydroartemisinin-piperaquine only; Type: ACTIVE_COMPARATOR; Interventions: Drug: dihydroartemisinin-piperaquine | Arm Label: DP and 0.125 mg/kg primaquine; Type: EXPERIMENTAL; Interventions: Drug: dihydroartemisinin-piperaquine, Drug: 0.125 mg/kg Primaquine | Arm Label: DP and 0.5 mg/kg primaquine; Type: EXPERIMENTAL; Interventions: Drug: dihydroartemisinin-piperaquine, Drug: 0.5 mg/kg Primaquine | Arm Label: DP and 0.25 mg/kg primaquine; Type: EXPERIMENTAL; Interventions: Drug: dihydroartemisinin-piperaquine, Drug: 0.25 mg/kg Primaquine | Arm Label: DP and 0.0625 mg/kg primaquine; Type: EXPERIMENTAL; Interventions: Drug: dihydroartemisinin-piperaquine, Drug: 0.0625 mg/kg Primaquine | Intervention Type: DRUG; Name: dihydroartemisinin-piperaquine; Assigned to Arm(s): DP and 0.0625 mg/kg primaquine, DP and 0.125 mg/kg primaquine, DP and 0.25 mg/kg primaquine, DP and 0.5 mg/kg primaquine, dihydroartemisinin-piperaquine only | Intervention Type: DRUG; Name: 0.125 mg/kg Primaquine; Assigned to Arm(s): DP and 0.125 mg/kg primaquine | Intervention Type: DRUG; Name: 0.5 mg/kg Primaquine; Assigned to Arm(s): DP and 0.5 mg/kg primaquine | Intervention Type: DRUG; Name: 0.25 mg/kg Primaquine; Assigned to Arm(s): DP and 0.25 mg/kg primaquine | Intervention Type: DRUG; Name: 0.0625 mg/kg Primaquine; Assigned to Arm(s): DP and 0.0625 mg/kg primaquine

Answer: C