Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Phase I Placebo-Controlled Study of the Infectivity, Safety and Immunogenicity of a Single Dose of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine, D46/NS2/N/ΔM2-2-HindIII, Lot RSV#011B, Delivered as Nose Drops to RSV-Seronegative Infants 6 to 24 Months of Age
Brief Summary: The purpose of this study was to evaluate the safety, infectivity, and immunogenicity of a single dose of a recombinant live-attenuated respiratory syncytial virus (RSV) vaccine in RSV-seronegative infants and children 6 to 24 months of age.

This study was a companion study to CIR 313.


Options:
A: Arm Label: Group A; Type: EXPERIMENTAL; Interventions: Biological: Low dose RSV-F Vaccine with Adjuvant | Arm Label: Group B; Type: EXPERIMENTAL; Interventions: Biological: Low dose RSV-F Vaccine with Adjuvant, Biological: Placebo | Arm Label: Group C; Type: EXPERIMENTAL; Interventions: Biological: Low dose RSV-F Vaccine without Adjuvant | Arm Label: Group D; Type: EXPERIMENTAL; Interventions: Biological: Low dose RSV-F Vaccine without Adjuvant, Biological: Placebo | Arm Label: Group E; Type: EXPERIMENTAL; Interventions: Biological: High dose RSV-F Vaccine with Adjuvant | Arm Label: Group F; Type: EXPERIMENTAL; Interventions: Biological: High dose RSV-F Vaccine with Adjuvant, Biological: Placebo | Arm Label: Group G; Type: EXPERIMENTAL; Interventions: Biological: High dose RSV-F Vaccine without Adjuvant | Arm Label: Group H; Type: EXPERIMENTAL; Interventions: Biological: High dose RSV-F Vaccine without Adjuvant, Biological: Placebo | Arm Label: Group J; Type: EXPERIMENTAL; Interventions: Biological: Low dose RSV-F Vaccine with Adjuvant [Bedside Mixing] | Arm Label: Group K; Type: PLACEBO_COMPARATOR; Interventions: Biological: Placebo | Intervention Type: BIOLOGICAL; Name: Low dose RSV-F Vaccine with Adjuvant; Assigned to Arm(s): Group A, Group B | Intervention Type: BIOLOGICAL; Name: Low dose RSV-F Vaccine without Adjuvant; Assigned to Arm(s): Group C, Group D | Intervention Type: BIOLOGICAL; Name: High dose RSV-F Vaccine with Adjuvant; Assigned to Arm(s): Group E, Group F | Intervention Type: BIOLOGICAL; Name: High dose RSV-F Vaccine without Adjuvant; Assigned to Arm(s): Group G, Group H | Intervention Type: BIOLOGICAL; Name: Low dose RSV-F Vaccine with Adjuvant [Bedside Mixing]; Assigned to Arm(s): Group J | Intervention Type: BIOLOGICAL; Name: Placebo; Assigned to Arm(s): Group B, Group D, Group F, Group H, Group K
B: Arm Label: RSV D46/NS2/N/ΔM2-2-HindIII Vaccine; Type: EXPERIMENTAL; Interventions: Biological: D46/NS2/N/ΔM2-2-HindIII | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Biological: Placebo | Intervention Type: BIOLOGICAL; Name: D46/NS2/N/ΔM2-2-HindIII; Assigned to Arm(s): RSV D46/NS2/N/ΔM2-2-HindIII Vaccine | Intervention Type: BIOLOGICAL; Name: Placebo; Assigned to Arm(s): Placebo
C: Arm Label: Treatment Group A; Type: PLACEBO_COMPARATOR; Interventions: Biological: Formulation buffer | Arm Label: Treatment Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: RSV F vaccine with adjuvant | Intervention Type: BIOLOGICAL; Name: RSV F vaccine with adjuvant; Assigned to Arm(s): Treatment Group | Intervention Type: BIOLOGICAL; Name: Formulation buffer; Assigned to Arm(s): Treatment Group A
D: Arm Label: Vitamin D and gargling; Type: EXPERIMENTAL; Interventions: Dietary Supplement: cholecalciferol (vitamin D3), Behavioral: Gargling | Arm Label: Vitamin D and general health advice; Type: EXPERIMENTAL; Interventions: Dietary Supplement: cholecalciferol (vitamin D3) | Arm Label: Placebo and general health advice; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Placebo | Arm Label: Placebo and gargling; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Gargling, Dietary Supplement: Placebo | Intervention Type: DIETARY_SUPPLEMENT; Name: cholecalciferol (vitamin D3); Assigned to Arm(s): Vitamin D and gargling, Vitamin D and general health advice | Intervention Type: BEHAVIORAL; Name: Gargling; Assigned to Arm(s): Placebo and gargling, Vitamin D and gargling | Intervention Type: DIETARY_SUPPLEMENT; Name: Placebo; Assigned to Arm(s): Placebo and gargling, Placebo and general health advice

Answer: B