Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Continuous Saphenous Nerve Block (Adductor Channel) and Local Infiltration Analgesia (LIA) for Total Knee Arthroplasty
Brief Summary: Our study will compare the use of continuous saphenous nerve block performed at the adductor canal in addition to Local Infiltration Analgesia (LIA) versus a Sham block in addition to LIA for total knee replacement. The investigators hypothesize that the saphenous nerve block performed at the level of the adductor canal in addition to LIA provides better pain relief than the LIA alone without significantly compromising muscle strength and physiotherapy, enabling patients to mobilize early with reduced opioid consumption and les side effects.

The investigators will enroll a total of 40 patients (20 patients will receive continuous saphenous nerve block in addition to LIA and 20 will receive the sham block and LIA). Until discharge, the investigators will record patients' pain scores, opioid consumption, side effects and physical therapy progress.

If our study proves that the continuous saphenous nerve block in addition to LIA can effectively reduce postoperative pain scores to an acceptable level with better physical therapy progress and less opioid consumption, it could be seen as a more attractive alternative to LIA alone or other traditionally used methods of postoperative pain control that compromises muscle strength and physiotherapy.


Options:
A: Arm Label: Saline boluses in nerve catheter; Type: SHAM_COMPARATOR; Interventions: Procedure: Saline boluses in nerve catheter | Arm Label: Continuous saphenous nerve block; Type: ACTIVE_COMPARATOR; Interventions: Procedure: continuous saphenous nerve block | Intervention Type: PROCEDURE; Name: continuous saphenous nerve block; Assigned to Arm(s): Continuous saphenous nerve block | Intervention Type: PROCEDURE; Name: Saline boluses in nerve catheter; Assigned to Arm(s): Saline boluses in nerve catheter
B: Arm Label: Adductor-Canal-Blockade with Ropivacaine; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Adductor-Canal-Blockade with Ropivacaine | Arm Label: Adductor-Canal-blockade with saline; Type: PLACEBO_COMPARATOR; Interventions: Procedure: Adductor-Canal-blockade with saline | Intervention Type: PROCEDURE; Name: Adductor-Canal-Blockade with Ropivacaine; Assigned to Arm(s): Adductor-Canal-Blockade with Ropivacaine | Intervention Type: PROCEDURE; Name: Adductor-Canal-blockade with saline; Assigned to Arm(s): Adductor-Canal-blockade with saline
C: Arm Label: Epidural Catheter without Adductor Canal Nerve Block Catheter; Type: SHAM_COMPARATOR; Interventions: Device: Adductor Canal Nerve Block Sham Catheter, Drug: Bupivacaine | Arm Label: Epidural Catheter with Adductor Canal Nerve Block Catheter; Type: EXPERIMENTAL; Interventions: Device: Adductor Canal Nerve Block Catheter, Drug: Bupivacaine | Intervention Type: DEVICE; Name: Adductor Canal Nerve Block Catheter; Assigned to Arm(s): Epidural Catheter with Adductor Canal Nerve Block Catheter | Intervention Type: DEVICE; Name: Adductor Canal Nerve Block Sham Catheter; Assigned to Arm(s): Epidural Catheter without Adductor Canal Nerve Block Catheter | Intervention Type: DRUG; Name: Bupivacaine; Assigned to Arm(s): Epidural Catheter with Adductor Canal Nerve Block Catheter, Epidural Catheter without Adductor Canal Nerve Block Catheter
D: Arm Label: Femoral nerve block; Type: EXPERIMENTAL; Interventions: Procedure: Sono guided nerve block | Arm Label: Adductor canal block; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Sono guided nerve block | Intervention Type: PROCEDURE; Name: Sono guided nerve block; Assigned to Arm(s): Adductor canal block, Femoral nerve block

Answer: A