Please select the eligibility criteria that correspond to the clinical trial below.
Title: Adherence to IDDM Regimen in Urban Youth
Brief Summary: The protocol is a randomized clinical trial providing Multisystemic Therapy (MST), an intensive home-based family psychotherapy intervention, to a group of urban adolescents with poorly controlled Type 1 diabetes and their families.


Options:
A: Inclusion Criteria:

* diagnosis of chronic daily headache based on definition of 15 or more headache days per month measured by a prospective daily headache diary
* females or males between the ages of 10-17
* PedMIDAS Disability Score \> 20, indicating at least moderate disruption in daily activities

Exclusion Criteria:

* medication overuse as defined in the ICHD-II criteria (NSAID or other simple analgesic on ≥ 15 days/ month for \>3 months; triptan intake in any formulation ≥ 10 days/month on a regular basis of ≥ 3 months)
* current treatment with amitriptyline
* no other current prophylactic antimigraine medication within a period equivalent to \< 5 half-lives of that medication before entering the screening phase
* other chronic pain condition such as juvenile primary fibromyalgia syndrome, complex regional pain syndrome-II
* abnormal findings on EKG
* current or past history of severe orthostatic intolerance or severe levels of orthostatic dysregulation (orthostatic hypotension or postural orthostatic tachycardia syndrome)
* significant documented developmental delay or impairments such as autism, cerebral palsy or mental retardation
* present or lifetime psychiatric diagnosis that meets DSM-IV criteria for bipolar disorder, major depressive disorder or psychosis
* PedMIDAS Disability Score of \> 140, indicating need for multi-systemic therapies to address very significant level of disability
* youth who are pregnant, or those females who are sexually active and not using a medically accepted form of contraception (barrier or hormonal methods) or do not agree to be abstinent during the study
* disallowed medications/products: opioids, antipsychotics, antimanics, barbiturates, benzodiazepines, muscle relaxants, sedatives, tramadol
B: Inclusion Criteria:

* a current hemoglobin A1c(HbA1c) of \>8.0%
* an average HbA1c of \>8.0% during the past year
* diagnosed with Type 1 diabetes for at least one year
* reside in the metro Detroit tri-county area

Exclusion Criteria:

* severe mental impairment/thought disorder
* non-English speaking patient/parent
* co-morbid major medical condition such as cystic fibrosis
C: Inclusion Criteria:

* patient age 11-18 years
* patient English speaking
* patient legal guardian willing to participate
* patient on oral IBD maintenance medication for 3 months or longer

Exclusion Criteria:

* history of significant parent-reported cognitive or developmental delay
D: Inclusion Criteria:

* between 11 and 18 years of age
* moderate to severe traumatic brain injury
* overnight hospital stay
* injury occurred within the last 12 months

Exclusion Criteria:

* younger than 11 and older than 18 years of age
* injury occurred more than 12 months ago
* teen does not live with parents or guardian
* English not spoken in the home
* injury is a result of child abuse as documented by medical record
* child or parent has history of hospitalization for a psychiatric problem
* documentation that the injury is a result of child abuse
* child suffered a non-blunt injury (e.g. projectile wounds, stroke, drowning, or other form of asphyxiation)
* child ever diagnosed with moderate or severe mental retardation, Autism, or a significant developmental disability (child must be able to talk)
* plans for the child to leave home during the coming 12 months.

Answer: B