Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Preventing Linear Growth Faltering and Reversal of Stunting Among Low Birth Weight Infants in Bangladesh: a Community-based Cluster Randomized Control Trial
Brief Summary: Low birth weight (LBW) infants are particularly vulnerable to frequent infections and consequent morbidity resulting in sub-optimal breastfeeding, limited ingestion of complementary foods and ultimately micronutrient deficiencies that result in post-natal linear growth faltering. The objective of this study is to facilitate improved feeding practices through the early reduction of infections using the innovative tools of water-based hand sanitizer (beginning at birth) and an improved micronutrient powder (I-MNP) (beginning at 6 months of age). A community-based cluster randomized controlled trial will be carried out in Bangladesh using a 2x2 factorial design. LBW infants (n=480) will be recruited at birth and allocated to either HS or No HS from 0 to 6 months. From 6 to 12 months, half of the children in each group will be randomized to receive I-MNP. All groups will receive nutrition and hygiene education from birth to 12 months. Recumbent length is the primary outcome; morbidity, dietary intake and hemoglobin will be assessed as secondary outcomes. By working with BRAC, the largest implementation agency in Bangladesh, there is the opportunity to translate the results directly and quickly into child health programs in Bangladesh.


Options:
A: Arm Label: Hand hygiene with Hand Sanitizer (HS); Type: EXPERIMENTAL; Interventions: Other: Hand Sanitizer | Arm Label: Hand hygiene with no Hand Sanitizer; Type: EXPERIMENTAL; Interventions: Other: Hand Sanitizer, Dietary Supplement: Improved Micronutrient Powder | Arm Label: Micronutrient Powder; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Improved Micronutrient Powder, Dietary Supplement: No Micronutrient Powder | Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Other: No hand sanitizer, Dietary Supplement: No Micronutrient Powder | Intervention Type: OTHER; Name: Hand Sanitizer; Assigned to Arm(s): Hand hygiene with Hand Sanitizer (HS), Hand hygiene with no Hand Sanitizer | Intervention Type: DIETARY_SUPPLEMENT; Name: Improved Micronutrient Powder; Assigned to Arm(s): Hand hygiene with no Hand Sanitizer, Micronutrient Powder | Intervention Type: OTHER; Name: No hand sanitizer; Assigned to Arm(s): Control | Intervention Type: DIETARY_SUPPLEMENT; Name: No Micronutrient Powder; Assigned to Arm(s): Control, Micronutrient Powder
B: Arm Label: Burundi: T24; Type: EXPERIMENTAL; Interventions: Other: Tubaramure (Burundi) | Arm Label: Burundi: TNFP; Type: EXPERIMENTAL; Interventions: Other: Tubaramure (Burundi) | Arm Label: Burundi: T18; Type: EXPERIMENTAL; Interventions: Other: Tubaramure (Burundi) | Arm Label: Burundi: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Guatemala: PROCOMIDA; Type: EXPERIMENTAL; Interventions: Other: Procomida (Guatemala) | Arm Label: Guatemala: no family ration; Type: EXPERIMENTAL; Interventions: Other: Procomida (Guatemala) | Arm Label: Guatemala: LNS; Type: EXPERIMENTAL; Interventions: Other: Procomida (Guatemala) | Arm Label: Guatemala: Sprinkles; Type: EXPERIMENTAL; Interventions: Other: Procomida (Guatemala) | Arm Label: Guatemala: reduced family ration; Type: EXPERIMENTAL; Interventions: Other: Procomida (Guatemala) | Arm Label: Guatemala: control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Tubaramure (Burundi); Assigned to Arm(s): Burundi: T18, Burundi: T24, Burundi: TNFP | Intervention Type: OTHER; Name: Procomida (Guatemala); Assigned to Arm(s): Guatemala: LNS, Guatemala: PROCOMIDA, Guatemala: Sprinkles, Guatemala: no family ration, Guatemala: reduced family ration
C: Arm Label: Vitamin/mineral fortificant with iron; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Sprinkles® | Arm Label: Vitamin/mineral fortificant without iron; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: vitamin/mineral fortificant without iron | Intervention Type: DIETARY_SUPPLEMENT; Name: Sprinkles®; Assigned to Arm(s): Vitamin/mineral fortificant with iron | Intervention Type: DIETARY_SUPPLEMENT; Name: vitamin/mineral fortificant without iron; Assigned to Arm(s): Vitamin/mineral fortificant without iron
D: Arm Label: MixMe powder (iron & micronutrients); Type: EXPERIMENTAL; Interventions: Dietary Supplement: fortification with iron and micronutrients | Arm Label: MixMe powder (micronutrients, no iron); Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: fortification with iron and micronutrients | Arm Label: Sprinkles (iron and micronutrients); Type: EXPERIMENTAL; Interventions: Dietary Supplement: Sprinkles | Arm Label: Sprinkles (micronutrients, no iron); Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Sprinkles | Intervention Type: DIETARY_SUPPLEMENT; Name: fortification with iron and micronutrients; Assigned to Arm(s): MixMe powder (iron & micronutrients), MixMe powder (micronutrients, no iron) | Intervention Type: DIETARY_SUPPLEMENT; Name: Sprinkles; Assigned to Arm(s): Sprinkles (iron and micronutrients), Sprinkles (micronutrients, no iron)

Answer: A