Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase 1 Study To Evaluate The Safety, Tolerability, And Pharmacokinetics Of PNU-100480 (PF-02341272) After First Time Administration Of Ascending Oral Doses To Healthy Adult Subjects Under Fed And Fasted Conditions
Brief Summary: The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of PNU-100480 (PF-02341272) after a single dose in healthy adult volunteers.


Options:
A: Arm Label: Cohort 1; Type: EXPERIMENTAL; Interventions: Drug: PNU-100480, Drug: Placebo | Arm Label: Cohort 2; Type: EXPERIMENTAL; Interventions: Drug: PNU-100480, Drug: Placebo | Arm Label: Cohort 3; Type: EXPERIMENTAL; Interventions: Drug: PNU-100480, Drug: Placebo | Arm Label: Cohort 4; Type: EXPERIMENTAL; Interventions: Drug: PNU-100480, Drug: Placebo | Arm Label: Cohort 5; Type: EXPERIMENTAL; Interventions: Drug: PNU-100480, Drug: Placebo | Arm Label: Cohort 6 (optional); Type: EXPERIMENTAL; Interventions: Drug: PNU-100480, Drug: Placebo | Arm Label: Linezolid Cohort; Type: EXPERIMENTAL; Interventions: Drug: Linezolid | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 1 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Cohort 1 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 2 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Cohort 2 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 3 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Cohort 3 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 4 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Cohort 4 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 5 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Cohort 5 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 6 (optional) | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Cohort 6 (optional) | Intervention Type: DRUG; Name: Linezolid; Assigned to Arm(s): Linezolid Cohort
B: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: Moxifloxacin | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Drug: Moxifloxacin | Intervention Type: DRUG; Name: Moxifloxacin; Assigned to Arm(s): 1, 2
C: Arm Label: TMC207 Stage 1; Type: EXPERIMENTAL; Interventions: Drug: TMC207, Drug: Background regimen (BR) for MDR-TB (multi-drug resistant tuberculosis) | Arm Label: Placebo Stage 1; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo, Drug: Background regimen (BR) for MDR-TB (multi-drug resistant tuberculosis) | Arm Label: TMC207 Stage 2; Type: EXPERIMENTAL; Interventions: Drug: TMC207, Drug: Background regimen (BR) for MDR-TB (multi-drug resistant tuberculosis) | Arm Label: Placebo Stage 2; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo, Drug: Background regimen (BR) for MDR-TB (multi-drug resistant tuberculosis) | Intervention Type: DRUG; Name: TMC207; Assigned to Arm(s): TMC207 Stage 1, TMC207 Stage 2 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo Stage 1, Placebo Stage 2 | Intervention Type: DRUG; Name: Background regimen (BR) for MDR-TB (multi-drug resistant tuberculosis); Assigned to Arm(s): Placebo Stage 1, Placebo Stage 2, TMC207 Stage 1, TMC207 Stage 2
D: Arm Label: Cohort 1, Sequence 1; Type: EXPERIMENTAL; Interventions: Drug: PNU-100480, Drug: Placebo | Arm Label: Cohort 1, Sequence 2; Type: EXPERIMENTAL; Interventions: Drug: PNU-100480, Drug: Placebo | Arm Label: Cohort 1, Sequence 3; Type: EXPERIMENTAL; Interventions: Drug: PNU-100480, Drug: Placebo | Arm Label: Cohort 2, Sequence 1; Type: EXPERIMENTAL; Interventions: Drug: PNU-100480, Drug: Placebo | Arm Label: Cohort 2, Sequence 2; Type: EXPERIMENTAL; Interventions: Drug: PNU-100480, Drug: Placebo | Arm Label: Cohort 2, Sequence 3; Type: EXPERIMENTAL; Interventions: Drug: PNU-100480, Drug: Placebo | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 1, Sequence 1 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 1, Sequence 1 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Cohort 1, Sequence 1 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 1, Sequence 2 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 1, Sequence 2 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Cohort 1, Sequence 2 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 1, Sequence 3 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 1, Sequence 3 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Cohort 1, Sequence 3 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 2, Sequence 1 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 2, Sequence 1 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 2, Sequence 1 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Cohort 2, Sequence 1 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 2, Sequence 2 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 2, Sequence 2 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 2, Sequence 2 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Cohort 2, Sequence 2 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 2, Sequence 3 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 2, Sequence 3 | Intervention Type: DRUG; Name: PNU-100480; Assigned to Arm(s): Cohort 2, Sequence 3 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Cohort 2, Sequence 3

Answer: D