Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Sertraline for Alcohol Dependence and Depression
Brief Summary: This study will examine depressed alcoholic outpatients to assess whether combining naltrexone (Revia) and sertraline (Zoloft) will result in greater reductions in both drinking and depression over either medication alone or placebo. A secondary aim is to determine whether certain patient features will predict response to sertraline, naltrexone or the combination of the two drugs. Subjects will be randomized into treatment groups for 14 weeks. The followup phase includes two visits at 6 and 9 months after treatment.


Options:
A: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Other: active venlafaxine and active rTMS-repetitive transcranial magnetic stimulator, Inomed and Alpine Biomed | Arm Label: B; Type: EXPERIMENTAL; Interventions: Other: active rTMS -repetitive transcranial magnetic stimulator, Inomed and Alpine Biomed and sham venlafaxine | Arm Label: C; Type: SHAM_COMPARATOR; Interventions: Other: sham rTMS- repetitive transcranial magnetic stimulator, Inomed and Alpine Biomed and active venlafaxine | Intervention Type: OTHER; Name: active venlafaxine and active rTMS-repetitive transcranial magnetic stimulator, Inomed and Alpine Biomed; Assigned to Arm(s): A | Intervention Type: OTHER; Name: active rTMS -repetitive transcranial magnetic stimulator, Inomed and Alpine Biomed and sham venlafaxine; Assigned to Arm(s): B | Intervention Type: OTHER; Name: sham rTMS- repetitive transcranial magnetic stimulator, Inomed and Alpine Biomed and active venlafaxine; Assigned to Arm(s): C
B: Intervention Type: DRUG; Name: citalopram; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: BuproprionSR; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: buspirone; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Lithium; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: mirtazapine; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: nortriptyline; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: sertraline; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: tranylcypromine; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: VenlafaxineXR; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: Cognitive Therapy; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: T3 (Triiodothyronine); Assigned to Arm(s): N/A
C: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Drug: Escitalopram | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Drug: Sertraline | Arm Label: C; Type: ACTIVE_COMPARATOR; Interventions: Drug: Venlafaxine-XR | Arm Label: D; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: Escitalopram; Assigned to Arm(s): A | Intervention Type: DRUG; Name: Sertraline; Assigned to Arm(s): B | Intervention Type: DRUG; Name: Venlafaxine-XR; Assigned to Arm(s): C
D: Arm Label: Sertraline; Type: EXPERIMENTAL; Interventions: Drug: sertraline (Zoloft) | Arm Label: Naltrexone; Type: EXPERIMENTAL; Interventions: Drug: naltrexone (Revia) | Arm Label: Nal/Sert; Type: EXPERIMENTAL; Interventions: Drug: naltrexone (Revia), Drug: sertraline (Zoloft) | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: naltrexone (Revia); Assigned to Arm(s): Nal/Sert, Naltrexone | Intervention Type: DRUG; Name: sertraline (Zoloft); Assigned to Arm(s): Nal/Sert, Sertraline | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo

Answer: D