Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Community Clinic Test of Youth Anxiety and Depression Study
Brief Summary: Structured, manualized treatments have been developed for numerous mental health problems and disorders among children and adolescents, and a number of these have shown strong beneficial effects in clinical trials. Such findings have led to proposals that the empirically supported treatments be used to improve outcomes of conventional clinic treatment, which some research suggests may not be very effective. But can these lab-tested treatments actually work in service-oriented clinics with referred youth? Available evidence cannot tell us, because the therapists, conditions, and clientele in the laboratory efficacy tests tend to differ so markedly from those of clinical practice. To assess the clinical potential of efficacy-tested treatments, we need effectiveness research that tests these treatments in the crucible of clinical practice. To help begin this process, the proposed research focuses on a specific treatment program for a specific cluster of disorders: Kendall's (1994) cognitive-behavioral "Coping Cat" program for child and adolescent anxiety disorders. The program has shown unusually positive effects across a series of clinical trials in the U.S. and Australia, but it has never been tested in real-world clinical conditions. The proposed study will test the effectiveness of the treatment with clinic-referred youth, treated in community clinics, with the treatment carried out by clinic staff therapists. Some 128 youth, aged 9-14, referred for anxiety and diagnosed with anxiety disorders, will be randomly assigned to receive either the usual treatment in the clinic, or the Kendall program, carried out by clinic staff who have been trained to proficiency. Therapists for the two treatment conditions will also be chosen randomly, from a pool of volunteers. Outcome assessment at immediate post-treatment, 1-year, and 2-year follow-ups, will test effects across many outcomes. It is hypothesized that outcomes for youths treated using the cognitive-behavioral treatment will be superior to those treated using usual care.


Options:
A: Arm Label: Sertraline; Type: ACTIVE_COMPARATOR; Interventions: Drug: Sertraline (SRT) | Arm Label: CBT; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Cognitive Behavioral Therapy (CBT) | Arm Label: SRT + CBT; Type: ACTIVE_COMPARATOR; Interventions: Drug: Sertraline (SRT), Behavioral: Cognitive Behavioral Therapy (CBT) | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Sertraline (SRT); Assigned to Arm(s): SRT + CBT, Sertraline | Intervention Type: BEHAVIORAL; Name: Cognitive Behavioral Therapy (CBT); Assigned to Arm(s): CBT, SRT + CBT | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
B: Arm Label: Cognitive-Behavioral Therapy; Type: EXPERIMENTAL; Interventions: Behavioral: Cognitive-Behavioral Therapy | Arm Label: Wait-list; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Wait-list | Intervention Type: BEHAVIORAL; Name: Cognitive-Behavioral Therapy; Assigned to Arm(s): Cognitive-Behavioral Therapy | Intervention Type: BEHAVIORAL; Name: Wait-list; Assigned to Arm(s): Wait-list
C: Arm Label: Cognitive-behavioral therapy: Anxiety; Type: EXPERIMENTAL; Interventions: Behavioral: Cognitive behavioral therapy for youth anxiety | Arm Label: Usual care: Anxiety; Type: OTHER; Interventions: Other: Usual clinic care | Arm Label: Cognitive behavioral therapy: depression; Type: EXPERIMENTAL; Interventions: Behavioral: Cognitive behavioral treatment for youth depression | Arm Label: Usual care: Depression; Type: OTHER; Interventions: Other: Usual clinic care | Intervention Type: BEHAVIORAL; Name: Cognitive behavioral therapy for youth anxiety; Assigned to Arm(s): Cognitive-behavioral therapy: Anxiety | Intervention Type: OTHER; Name: Usual clinic care; Assigned to Arm(s): Usual care: Anxiety, Usual care: Depression | Intervention Type: BEHAVIORAL; Name: Cognitive behavioral treatment for youth depression; Assigned to Arm(s): Cognitive behavioral therapy: depression
D: Arm Label: Active Treatment: CBT; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: CBT | Arm Label: Experimental Treatment: SPACE; Type: EXPERIMENTAL; Interventions: Behavioral: Parent-Based Treatment of Child and Adolescent Anxiety Disorders | Intervention Type: BEHAVIORAL; Name: Parent-Based Treatment of Child and Adolescent Anxiety Disorders; Assigned to Arm(s): Experimental Treatment: SPACE | Intervention Type: BEHAVIORAL; Name: CBT; Assigned to Arm(s): Active Treatment: CBT

Answer: C