Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase 1, Multi-Center, Double-Blind, Single and Double Dose-Escalation Study to Evaluate the Safety, Tolerability, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of LymphoStat-B™ (Monoclonal Anti-BLyS Antibody) in Subjects With Systemic Lupus Erythematosus
Brief Summary: The purpose of thie study is to evaluate the safety, tolerability, immunogenicity, pharmacokinetics and pharmacodynamics of belimumab (LymphoStat-B™)in subjects with SLE.


Options:
A: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Biological: Placebo | Arm Label: Belimumab 1 mg/kg; Type: EXPERIMENTAL; Interventions: Biological: belimumab | Arm Label: Belimumab 4 mg/kg; Type: EXPERIMENTAL; Interventions: Biological: belimumab | Arm Label: Beimumab 10 mg/kg; Type: EXPERIMENTAL; Interventions: Biological: belimumab | Arm Label: Belimumab 20 mg/kg; Type: EXPERIMENTAL; Interventions: Biological: belimumab | Intervention Type: BIOLOGICAL; Name: belimumab; Assigned to Arm(s): Belimumab 1 mg/kg | Intervention Type: BIOLOGICAL; Name: belimumab; Assigned to Arm(s): Belimumab 4 mg/kg | Intervention Type: BIOLOGICAL; Name: belimumab; Assigned to Arm(s): Beimumab 10 mg/kg | Intervention Type: BIOLOGICAL; Name: belimumab; Assigned to Arm(s): Belimumab 20 mg/kg | Intervention Type: BIOLOGICAL; Name: Placebo; Assigned to Arm(s): Placebo
B: Arm Label: Placebo plus SOC; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: Belimumab 1 mg/kg plus SOC; Type: EXPERIMENTAL; Interventions: Drug: Belimumab 1 mg/kg | Arm Label: Belimumab 4 mg/kg plus SOC; Type: EXPERIMENTAL; Interventions: Drug: Belimumab 4 mg/kg | Arm Label: Belimumab 10 mg/kg plus SOC; Type: EXPERIMENTAL; Interventions: Drug: Belimumab 10 mg/kg | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo plus SOC | Intervention Type: DRUG; Name: Belimumab 1 mg/kg; Assigned to Arm(s): Belimumab 1 mg/kg plus SOC | Intervention Type: DRUG; Name: Belimumab 4 mg/kg; Assigned to Arm(s): Belimumab 4 mg/kg plus SOC | Intervention Type: DRUG; Name: Belimumab 10 mg/kg; Assigned to Arm(s): Belimumab 10 mg/kg plus SOC
C: Arm Label: Belimumab 10 mg/kg; Type: EXPERIMENTAL; Interventions: Biological: Belimumab | Intervention Type: BIOLOGICAL; Name: Belimumab; Assigned to Arm(s): Belimumab 10 mg/kg
D: Arm Label: Belimumab + Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Belimumab, Drug: Rituximab-placebo, Drug: Standard therapy (Excluding Immunosuppressants), Drug: Steroid Taper | Arm Label: Belimumab + Rituximab; Type: EXPERIMENTAL; Interventions: Drug: Belimumab, Drug: Rituximab, Drug: Standard therapy (Excluding Immunosuppressants), Drug: Steroid Taper | Arm Label: Belimumab + Standard therapy; Type: OTHER; Interventions: Drug: Belimumab, Drug: Standard therapy (Including Immunosuppressants), Drug: Steroid Taper | Intervention Type: DRUG; Name: Belimumab; Assigned to Arm(s): Belimumab + Placebo, Belimumab + Rituximab, Belimumab + Standard therapy | Intervention Type: DRUG; Name: Rituximab; Assigned to Arm(s): Belimumab + Rituximab | Intervention Type: DRUG; Name: Rituximab-placebo; Assigned to Arm(s): Belimumab + Placebo | Intervention Type: DRUG; Name: Standard therapy (Including Immunosuppressants); Assigned to Arm(s): Belimumab + Standard therapy | Intervention Type: DRUG; Name: Standard therapy (Excluding Immunosuppressants); Assigned to Arm(s): Belimumab + Placebo, Belimumab + Rituximab | Intervention Type: DRUG; Name: Steroid Taper; Assigned to Arm(s): Belimumab + Placebo, Belimumab + Rituximab, Belimumab + Standard therapy

Answer: A