Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Project 3: Identifying Optimal Strategies of Increasing Smokers' Adherence to Cessation Medications
Brief Summary: Many smokers fail to take their smoking cessation medication as recommended. This research is designed to identify treatments that improve the use of cessation medications and to determine whether an increase in medication use results in increased cessation success. This research will also identify treatments that help people stay quit after a quit attempt and will pioneer more efficient research methods.


Options:
A: Arm Label: Standard support; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Reactive (standard) telephone support | Arm Label: Proactive telephone support; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Proactive telephone support | Arm Label: Standard support & offer NRT; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Reactive (standard) telephone support, Drug: Offer of voucher for cost-free Nicotine Replacement Therapy | Arm Label: Proactive support & offer NRT; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Proactive telephone support, Drug: Offer of voucher for cost-free Nicotine Replacement Therapy | Intervention Type: BEHAVIORAL; Name: Proactive telephone support; Assigned to Arm(s): Proactive support & offer NRT, Proactive telephone support | Intervention Type: BEHAVIORAL; Name: Reactive (standard) telephone support; Assigned to Arm(s): Standard support, Standard support & offer NRT | Intervention Type: DRUG; Name: Offer of voucher for cost-free Nicotine Replacement Therapy; Assigned to Arm(s): Proactive support & offer NRT, Standard support & offer NRT
B: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Other: Varenicline plus Motivational Interviewing counseling | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Other: Varenicline without counseling | Intervention Type: OTHER; Name: Varenicline plus Motivational Interviewing counseling; Assigned to Arm(s): 1 | Intervention Type: OTHER; Name: Varenicline without counseling; Assigned to Arm(s): 2
C: Arm Label: Group I (standard care); Type: ACTIVE_COMPARATOR; Interventions: Other: Laboratory Biomarker Analysis, Behavioral: Smoking Cessation Intervention | Arm Label: Group II (enhanced care); Type: EXPERIMENTAL; Interventions: Other: Laboratory Biomarker Analysis, Behavioral: Smoking Cessation Intervention, Other: Tobacco Cessation Counseling | Arm Label: Group III (intensive care); Type: EXPERIMENTAL; Interventions: Other: Laboratory Biomarker Analysis, Behavioral: Smoking Cessation Intervention, Behavioral: Telephone-Based Intervention, Other: Tobacco Cessation Counseling | Intervention Type: OTHER; Name: Laboratory Biomarker Analysis; Assigned to Arm(s): Group I (standard care), Group II (enhanced care), Group III (intensive care) | Intervention Type: BEHAVIORAL; Name: Smoking Cessation Intervention; Assigned to Arm(s): Group I (standard care), Group II (enhanced care), Group III (intensive care) | Intervention Type: BEHAVIORAL; Name: Telephone-Based Intervention; Assigned to Arm(s): Group III (intensive care) | Intervention Type: OTHER; Name: Tobacco Cessation Counseling; Assigned to Arm(s): Group II (enhanced care), Group III (intensive care)
D: Arm Label: 1, 26Wks, Counseling, CAM, AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling, Behavioral: Cognitive Medication Adherence Counseling (CAM), Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback, Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 2, 26Wks, Counseling, CAM, AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling, Behavioral: Cognitive Medication Adherence Counseling (CAM), Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 3, 26Wks, Counseling, CAM, No AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling, Behavioral: Cognitive Medication Adherence Counseling (CAM), Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback | Arm Label: 4, 26Wks, Counseling, CAM, No AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling, Behavioral: Cognitive Medication Adherence Counseling (CAM) | Arm Label: 5, 26Wks, Counseling, No CAM, AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling, Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback, Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 6, 26Wks, Counseling, No CAM, AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling, Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 7, 26Wks, Counseling, No CAM, No AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling, Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback | Arm Label: 8, 26Wks, Counseling, No CAM, No AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling | Arm Label: 9, 26Wks, No Counseling, CAM, AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Cognitive Medication Adherence Counseling (CAM), Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback, Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 10, 26Wks, No Counseling, CAM, AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Cognitive Medication Adherence Counseling (CAM), Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 11, 26Wks, No Counseling, CAM, No AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Cognitive Medication Adherence Counseling (CAM), Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback | Arm Label: 12, 26Wks, No Counseling, CAM, No AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Cognitive Medication Adherence Counseling (CAM) | Arm Label: 13, 26Wks, No Counseling, No CAM, AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback, Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 14, 26Wks, No Counseling, No CAM, AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 15, 26Wks, No Counseling, No CAM, No AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback | Arm Label: 16, 26Wks, No Counseling, No CAM, No AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Long Term Combination Nicotine Replacement Therapy (patch + gum) | Arm Label: 17, 8Wks, Counseling, CAM, AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling, Behavioral: Cognitive Medication Adherence Counseling (CAM), Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback, Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 18, 8Wks, Counseling, CAM, AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling, Behavioral: Cognitive Medication Adherence Counseling (CAM), Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 19, 8Wks, Counseling, CAM, No AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling, Behavioral: Cognitive Medication Adherence Counseling (CAM), Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback | Arm Label: 20, 8Wks, Counseling, CAM, No AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling, Behavioral: Cognitive Medication Adherence Counseling (CAM) | Arm Label: 21, 8Wks, Counseling, No CAM, AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling, Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback, Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 22, 8Wks, Counseling, No CAM, AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling, Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 23, 8Wks, Counseling, No CAM, No AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling, Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback | Arm Label: 24, 8Wks, Counseling, No CAM, No AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Intensive Maintenance Counseling | Arm Label: 25, 8Wks, No Counseling, CAM, AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Cognitive Medication Adherence Counseling (CAM), Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback, Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 26, 8Wks, No Counseling, CAM, AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Cognitive Medication Adherence Counseling (CAM), Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 27, 8Wks, No Counseling, CAM, No AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Cognitive Medication Adherence Counseling (CAM), Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback | Arm Label: 28, 8Wks, No Counseling, CAM, No AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Cognitive Medication Adherence Counseling (CAM) | Arm Label: 29, 8Wks, No Counseling, No CAM, AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback, Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 30, 8Wks, No Counseling, No CAM, AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Automated Adherence Prompting Phone Calls | Arm Label: 31, 8Wks, No Counseling, No CAM, No AutoCalls, Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum), Behavioral: Electronic Medication Monitoring Device (the Helping Hand) + Feedback | Arm Label: 32, 8Wks, No Counseling, No CAM, No AutoCalls, No Feedback; Type: EXPERIMENTAL; Interventions: Drug: Short Term Combination Nicotine Replacement Therapy (patch + gum) | Intervention Type: DRUG; Name: Short Term Combination Nicotine Replacement Therapy (patch + gum); Assigned to Arm(s): 17, 8Wks, Counseling, CAM, AutoCalls, Feedback, 18, 8Wks, Counseling, CAM, AutoCalls, No Feedback, 19, 8Wks, Counseling, CAM, No AutoCalls, Feedback, 20, 8Wks, Counseling, CAM, No AutoCalls, No Feedback, 21, 8Wks, Counseling, No CAM, AutoCalls, Feedback, 22, 8Wks, Counseling, No CAM, AutoCalls, No Feedback, 23, 8Wks, Counseling, No CAM, No AutoCalls, Feedback, 24, 8Wks, Counseling, No CAM, No AutoCalls, No Feedback, 25, 8Wks, No Counseling, CAM, AutoCalls, Feedback, 26, 8Wks, No Counseling, CAM, AutoCalls, No Feedback, 27, 8Wks, No Counseling, CAM, No AutoCalls, Feedback, 28, 8Wks, No Counseling, CAM, No AutoCalls, No Feedback, 29, 8Wks, No Counseling, No CAM, AutoCalls, Feedback, 30, 8Wks, No Counseling, No CAM, AutoCalls, No Feedback, 31, 8Wks, No Counseling, No CAM, No AutoCalls, Feedback, 32, 8Wks, No Counseling, No CAM, No AutoCalls, No Feedback | Intervention Type: DRUG; Name: Long Term Combination Nicotine Replacement Therapy (patch + gum); Assigned to Arm(s): 1, 26Wks, Counseling, CAM, AutoCalls, Feedback, 10, 26Wks, No Counseling, CAM, AutoCalls, No Feedback, 11, 26Wks, No Counseling, CAM, No AutoCalls, Feedback, 12, 26Wks, No Counseling, CAM, No AutoCalls, No Feedback, 13, 26Wks, No Counseling, No CAM, AutoCalls, Feedback, 14, 26Wks, No Counseling, No CAM, AutoCalls, No Feedback, 15, 26Wks, No Counseling, No CAM, No AutoCalls, Feedback, 16, 26Wks, No Counseling, No CAM, No AutoCalls, No Feedback, 2, 26Wks, Counseling, CAM, AutoCalls, No Feedback, 3, 26Wks, Counseling, CAM, No AutoCalls, Feedback, 4, 26Wks, Counseling, CAM, No AutoCalls, No Feedback, 5, 26Wks, Counseling, No CAM, AutoCalls, Feedback, 6, 26Wks, Counseling, No CAM, AutoCalls, No Feedback, 7, 26Wks, Counseling, No CAM, No AutoCalls, Feedback, 8, 26Wks, Counseling, No CAM, No AutoCalls, No Feedback, 9, 26Wks, No Counseling, CAM, AutoCalls, Feedback | Intervention Type: BEHAVIORAL; Name: Intensive Maintenance Counseling; Assigned to Arm(s): 1, 26Wks, Counseling, CAM, AutoCalls, Feedback, 17, 8Wks, Counseling, CAM, AutoCalls, Feedback, 18, 8Wks, Counseling, CAM, AutoCalls, No Feedback, 19, 8Wks, Counseling, CAM, No AutoCalls, Feedback, 2, 26Wks, Counseling, CAM, AutoCalls, No Feedback, 20, 8Wks, Counseling, CAM, No AutoCalls, No Feedback, 21, 8Wks, Counseling, No CAM, AutoCalls, Feedback, 22, 8Wks, Counseling, No CAM, AutoCalls, No Feedback, 23, 8Wks, Counseling, No CAM, No AutoCalls, Feedback, 24, 8Wks, Counseling, No CAM, No AutoCalls, No Feedback, 3, 26Wks, Counseling, CAM, No AutoCalls, Feedback, 4, 26Wks, Counseling, CAM, No AutoCalls, No Feedback, 5, 26Wks, Counseling, No CAM, AutoCalls, Feedback, 6, 26Wks, Counseling, No CAM, AutoCalls, No Feedback, 7, 26Wks, Counseling, No CAM, No AutoCalls, Feedback, 8, 26Wks, Counseling, No CAM, No AutoCalls, No Feedback | Intervention Type: BEHAVIORAL; Name: Cognitive Medication Adherence Counseling (CAM); Assigned to Arm(s): 1, 26Wks, Counseling, CAM, AutoCalls, Feedback, 10, 26Wks, No Counseling, CAM, AutoCalls, No Feedback, 11, 26Wks, No Counseling, CAM, No AutoCalls, Feedback, 12, 26Wks, No Counseling, CAM, No AutoCalls, No Feedback, 17, 8Wks, Counseling, CAM, AutoCalls, Feedback, 18, 8Wks, Counseling, CAM, AutoCalls, No Feedback, 19, 8Wks, Counseling, CAM, No AutoCalls, Feedback, 2, 26Wks, Counseling, CAM, AutoCalls, No Feedback, 20, 8Wks, Counseling, CAM, No AutoCalls, No Feedback, 25, 8Wks, No Counseling, CAM, AutoCalls, Feedback, 26, 8Wks, No Counseling, CAM, AutoCalls, No Feedback, 27, 8Wks, No Counseling, CAM, No AutoCalls, Feedback, 28, 8Wks, No Counseling, CAM, No AutoCalls, No Feedback, 3, 26Wks, Counseling, CAM, No AutoCalls, Feedback, 4, 26Wks, Counseling, CAM, No AutoCalls, No Feedback, 9, 26Wks, No Counseling, CAM, AutoCalls, Feedback | Intervention Type: BEHAVIORAL; Name: Electronic Medication Monitoring Device (the Helping Hand) + Feedback; Assigned to Arm(s): 1, 26Wks, Counseling, CAM, AutoCalls, Feedback, 11, 26Wks, No Counseling, CAM, No AutoCalls, Feedback, 13, 26Wks, No Counseling, No CAM, AutoCalls, Feedback, 15, 26Wks, No Counseling, No CAM, No AutoCalls, Feedback, 17, 8Wks, Counseling, CAM, AutoCalls, Feedback, 19, 8Wks, Counseling, CAM, No AutoCalls, Feedback, 21, 8Wks, Counseling, No CAM, AutoCalls, Feedback, 23, 8Wks, Counseling, No CAM, No AutoCalls, Feedback, 25, 8Wks, No Counseling, CAM, AutoCalls, Feedback, 27, 8Wks, No Counseling, CAM, No AutoCalls, Feedback, 29, 8Wks, No Counseling, No CAM, AutoCalls, Feedback, 3, 26Wks, Counseling, CAM, No AutoCalls, Feedback, 31, 8Wks, No Counseling, No CAM, No AutoCalls, Feedback, 5, 26Wks, Counseling, No CAM, AutoCalls, Feedback, 7, 26Wks, Counseling, No CAM, No AutoCalls, Feedback, 9, 26Wks, No Counseling, CAM, AutoCalls, Feedback | Intervention Type: BEHAVIORAL; Name: Automated Adherence Prompting Phone Calls; Assigned to Arm(s): 1, 26Wks, Counseling, CAM, AutoCalls, Feedback, 10, 26Wks, No Counseling, CAM, AutoCalls, No Feedback, 13, 26Wks, No Counseling, No CAM, AutoCalls, Feedback, 14, 26Wks, No Counseling, No CAM, AutoCalls, No Feedback, 17, 8Wks, Counseling, CAM, AutoCalls, Feedback, 18, 8Wks, Counseling, CAM, AutoCalls, No Feedback, 2, 26Wks, Counseling, CAM, AutoCalls, No Feedback, 21, 8Wks, Counseling, No CAM, AutoCalls, Feedback, 22, 8Wks, Counseling, No CAM, AutoCalls, No Feedback, 25, 8Wks, No Counseling, CAM, AutoCalls, Feedback, 26, 8Wks, No Counseling, CAM, AutoCalls, No Feedback, 29, 8Wks, No Counseling, No CAM, AutoCalls, Feedback, 30, 8Wks, No Counseling, No CAM, AutoCalls, No Feedback, 5, 26Wks, Counseling, No CAM, AutoCalls, Feedback, 6, 26Wks, Counseling, No CAM, AutoCalls, No Feedback, 9, 26Wks, No Counseling, CAM, AutoCalls, Feedback

Answer: D