Please select the eligibility criteria that correspond to the clinical trial below.
Title: Phase 2 Study of Very Early Supported Discharge From a Stroke Unit in
Brief Summary: Stroke is a generic term for cerebral infarction and cerebral haemorrhage and accounts for more patient days than any other single condition in Swedish health care. The Swedish guidelines for stroke treatment, issued by the national board for health and welfare, recommend early supported discharge for people with mild to moderate stroke. This is based on studies in which mean hospitalization was 18 days. The average length of stay in Sweden is 12 days. Policy makers would, however, like to shorten length of stay even further, and many patients are anxious to get home. Where and how to get support at home after discharge varies.

This study is a randomized controlled trial in which half of the subjects are randomly allocated to very early supported discharge and the other half receives usual treatment. The investigators believe that patients discharged very early with support will experience less anxiety compared with controls. The investigators believe that early supported discharge is safe and that there is no difference between groups in bodily function. In order to test differences between the groups, the study requires approximately 110 subjects.

Everyone who comes to the stroke unit at the hospital with a mild to moderate stroke can be recruited to the study. The intervention is having a team from the stroke unit visiting the patient's home and train him/her according to the individualized goals. The controls are discharged according to routine with support from primary care if needed. Assessments are made by therapists who are not involved in the training upon returning home, at 1 month, 3 to 12 months. The assessments include anxiety, motor activity, gait and balance, and ADL. Interviews will be done to highlight the subject's own experience.

It is important to evaluate new methods and organizational changes prior to their implementation in health care. The investigators hope to show that very early supported discharge with rehabilitation is safe and provides confidence and less anxiety. Then it is possible to introduce a method that simultaneously improves patient outcome and increases availability of hospital beds.


Options:
A: Inclusion Criteria:

* Diagnosis of AP based on 2 out of 3 findings: characteristic abdominal pain, amylase and/or lipase levels ≥3 times the upper limit of normal, and/or abdominal imaging demonstrating changes of acute pancreatitis
* Presentation within 48 hours of symptom onset
* Imrie's scores of ≤5 and HAP score ≤2 within 24 hours of presentation to the hospital
* Lack of hemoconcentration (hematocrit ≥44%) on presentation since hemoconcentration has been shown to be a risk factor for pancreatic necrosis.

Exclusion Criteria:

* The presence of organ failure by the Atlanta criteria on the first day of presentation
* The presence of clinical signs and/or symptoms of sepsis
* Alcoholic acute pancreatitis
* A history of abdominal imaging demonstrating a dilated pancreatic duct and/or pancreatic calcifications
* Coagulopathy (international normalized ratio \>1, and/or platelet count \<50,000/mm3
* Comorbidities requiring hospitalization regardless of the presence of AP e.g. acute myocardial infarction, malignancy, cirrhosis, chronic kidney disease, and chronic pulmonary disease)
B: Inclusion Criteria:

* Living in own home in the community of Bergen, Norway
* Inclusion within 1-7 days (24-168 hours) after debut of symptoms
* Inclusion within 6-120 hours after admission to Department of Neurology
* NIHSS score 2-26 at inclusion OR NIHSS score \< 2 if Modified Rankin Scale is 2 or higher when being 0 before the stroke
* The patient must be awake and informed consent must be given by patient or relatives

Exclusion Criteria:

* Serious psychic illness
* Serious drug abuse
* Serious medical conditions that can influence the patients' cerebrovascular disease or rehabilitation
* Poor knowledge of the Norwegian language
C: Inclusion Criteria:

* Confirmed stroke according to WHO´s criteria
* \> 18 years of age
* Living within 30 min from the stroke unit
* On day 2 NIHSS (National institute of health stroke scale) (22) of 0-16 points and Barthel 50-100 points.
* MoCA index \< 26 if Barthel = 100.

Exclusion Criteria:

* NIHSS \> 16
* Barthel \< 50
* Life expectancy \< 1 year (as with severe malignancy)
* Does not speak or communicate in Swedish prior to the incidence
D: Inclusion Criteria:

* The consecutive outpatients subjects diagnosed of PE at 10 different Spanish hospitals.
* A score of 2 or under in our prediction rule (risk score for short-term)
* Signed written Informed consent

Exclusion Criteria:

* A score over 2 in our prediction rule
* Patients with a PE requiring thrombolysis or surgical thrombectomy
* Patients with right ventricular dyskinesia in echocardiography at 48 hours from heparin therapy. (It is not necessary echocardiography for the model of discharge at 5 days)
* Troponin level over 0,1 g/L
* Patiens requiring oxygen therapy or under 93% in oxygen saturation level.
* Patients requiring intravenous analgesic therapy
* Patients with some medical or surgical conditions requiring to stay at hospital
* Patients with advanced chronic cardiovascular diseases (dyspnea III-IV NYHA)
* Patients with advanced chronic respiratory diseases (several COPD criteria of GOLD with FEV1\< 50%)
* Documented congenital or acquired bleeding tendency /disorder (s)
* Documented current ulceration or angiodysplastic gastrointestinal disease
* Hemorrhagic stroke or recent (\< 3 months prior to randomization) brain, spinal, or ophthalmological surgery.
* Recent surgery \< 3 days
* Pregnancy
* Several Obesity (CMI over 30)
* Patients could not complete the treatment at home.
* Exclusion criteria related to study procedures
* Life expectancy \< 3 months

Answer: C