Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Efficacy, Safety, and Immunogenicity Study of GSK Biologicals' Herpes Zoster Vaccine GSK1437173A in Adults Aged 50 Years or Older
Brief Summary: The purpose of this observer-blind study is to evaluate the efficacy, safety and immunogenicity of GSK Biologicals' candidate Herpes Zoster (HZ) vaccine in adults aged ≥ 50 years.

Two studies \[ZOSTER-006 (NCT01165177) and ZOSTER-022 (NCT01165229)\] are being conducted concurrently to evaluate efficacy of GSK1437173A vaccine. A pooled analysis of data from both studies combined will be conducted contingent on each study achieving its objectives. The protocol posting of study ZOSTER-022 also deals with the outcome measures related to the pooled analysis.


Options:
A: Arm Label: Single Dose of Zostavax; Type: EXPERIMENTAL; Interventions: Biological: Zostavax | Arm Label: Zostavax - Day 0 and Month 1; Type: EXPERIMENTAL; Interventions: Biological: Zostavax | Arm Label: Zostavax - Day 0 and Month 3; Type: EXPERIMENTAL; Interventions: Biological: Zostavax | Intervention Type: BIOLOGICAL; Name: Zostavax; Assigned to Arm(s): Single Dose of Zostavax, Zostavax - Day 0 and Month 1, Zostavax - Day 0 and Month 3
B: Arm Label: GSK1437173A formulation 1 Group; Type: EXPERIMENTAL; Interventions: Biological: Herpes zoster vaccine GSK1437173A | Arm Label: GSK1437173A formulation 2 Group; Type: EXPERIMENTAL; Interventions: Biological: Herpes zoster vaccine GSK1437173A | Arm Label: GSK1437173A formulation 3 Group; Type: EXPERIMENTAL; Interventions: Biological: Herpes zoster vaccine GSK1437173A | Arm Label: Control Group; Type: PLACEBO_COMPARATOR; Interventions: Biological: Placebo | Intervention Type: BIOLOGICAL; Name: Herpes zoster vaccine GSK1437173A; Assigned to Arm(s): GSK1437173A formulation 1 Group, GSK1437173A formulation 2 Group, GSK1437173A formulation 3 Group | Intervention Type: BIOLOGICAL; Name: Placebo; Assigned to Arm(s): Control Group
C: Arm Label: GSK1437173A group; Type: EXPERIMENTAL; Interventions: Biological: Herpes Zoster Vaccine GSK1437173A | Arm Label: Placebo group; Type: PLACEBO_COMPARATOR; Interventions: Biological: Placebo | Intervention Type: BIOLOGICAL; Name: Herpes Zoster Vaccine GSK1437173A; Assigned to Arm(s): GSK1437173A group | Intervention Type: BIOLOGICAL; Name: Placebo; Assigned to Arm(s): Placebo group
D: Arm Label: GSK1437173A _LD Group; Type: EXPERIMENTAL; Interventions: Biological: Herpes Zoster vaccine GSK1437173A Low Dose | Arm Label: GSK1437173A _MD Group; Type: EXPERIMENTAL; Interventions: Biological: Herpes Zoster vaccine GSK1437173A Medium Dose | Arm Label: GSK1437173A _HD Group; Type: EXPERIMENTAL; Interventions: Biological: Herpes Zoster vaccine GSK1437173A High Dose | Arm Label: Placebo + GSK1437173A _HD Group; Type: PLACEBO_COMPARATOR; Interventions: Biological: Herpes Zoster vaccine GSK1437173A High Dose, Biological: Placebo | Arm Label: GSK1437173A_MODIFIED GROUP; Type: ACTIVE_COMPARATOR; Interventions: Biological: Herpes Zoster vaccine GSK1437173A Modified | Intervention Type: BIOLOGICAL; Name: Herpes Zoster vaccine GSK1437173A Low Dose; Assigned to Arm(s): GSK1437173A _LD Group | Intervention Type: BIOLOGICAL; Name: Herpes Zoster vaccine GSK1437173A Medium Dose; Assigned to Arm(s): GSK1437173A _MD Group | Intervention Type: BIOLOGICAL; Name: Herpes Zoster vaccine GSK1437173A High Dose; Assigned to Arm(s): GSK1437173A _HD Group, Placebo + GSK1437173A _HD Group | Intervention Type: BIOLOGICAL; Name: Herpes Zoster vaccine GSK1437173A Modified; Assigned to Arm(s): GSK1437173A_MODIFIED GROUP | Intervention Type: BIOLOGICAL; Name: Placebo; Assigned to Arm(s): Placebo + GSK1437173A _HD Group

Answer: C