Please select the eligibility criteria that correspond to the clinical trial below.
Title: Prospective Clinical Evaluation of Early Weight-Bearing After Lapidus Arthrodesis Using the Phantom™ Intramedullary Nail
Brief Summary: The goal of this research study is to determine if union rates are affected by early weight-bearing after Lapidus Arthrodesis using the Phantom™ Intramedullary Nail.

The study hypothesis is that the union rate for those who undergo a Lapidus Arthrodesis procedure with the Phantom™ Intramedullary Nail and participate in an early weight-bearing protocol will be non-inferior to union rates previously published for this procedure.


Options:
A: Inclusion Criteria:

* The subject is at least 18 years of age with closed physeal plates at the time of screening.
* The intermetatarsal angle is greater than or equal to 10 degrees.
* The hallux valgus angle is greater than or equal to 25 degrees.
* The subject has foot pain/discomfort on the foot in question.
* The subject has activity limitations due to the foot in question.
* The subject agrees to comply with the requirements of the study and complete the study measures.
* The subject is willing and able to provide written informed consent.

Exclusion Criteria:

* The subject is pregnant.
* The subject is a current smoker.
* The subject has been clinically diagnosed with diabetes.
* The subject has been clinically diagnosed with peripheral neuropathy.
* The subject had been previously sensitized to titanium.
* The subject currently takes oral steroids or rheumatoid biologics.
* The subject has had previous surgery for hallux valgus on operative side.
* The subject has insufficient quantity or quality of bone to permit stabilization, conditions that retard healing (not including pathological fractures) and conditions causing poor blood supply such as peripheral vascular disease.
* The subject has a history of delayed or non-union for fracture or joint.
* The subject has an active, suspected or latent infection in the affected area.
* The subject will require a structural graft in the 1st TMT joint.
* The subject is scheduled to undergo a concomitant 2nd tarsometatarsal joint arthrodesis procedure.
* The subject is scheduled to undergo a same-day bilateral procedure.
* The subject cannot be scheduled for surgery within 3 months of the pre-operative exam.
* The subject has previously been enrolled into this study for a contralateral procedure.
* The subject is actively involved with a Workman's Compensation case.
* The subject is not expected to complete the study according to the investigation plan.
* The subject has been deemed physiologically or psychologically inadequate by the enrolling physician.
* The subject is: a prisoner, unable to understand what participation in the study entails, mentally incompetent, a known abuser of alcohol and/or drugs or anticipated to be non-compliant.
B: Inclusion Criteria:

* Spirometry-proven COPD
* Referred for 6-month outpatient pulmonary rehabilitation program

Exclusion Criteria:

* Orthopedic problems impairing daily activities
* Progressive neurological or neuromuscular disorders
* Psychiatric or cognitive disorders
* Patients on the waiting list for lung transplantation
C: Inclusion criteria:

All subjects must have a diagnosis of Chronic Obstructive Pulmonary Disease (COPD) according to Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) guideline criteria:

post-bronchodilator Forced Expiratory Volume in one Second/Forced Vital Capacity (FEV1/FVC) ratio \< 70% (visit 1).

Subjects must be GOLD Stage II and have a post-bronchodilator FEV1 \>50% and \< 80% of predicted normal (visit 1). Subjects must be current or ex-smokers with a smoking history of \>=10 pack years.

Subjects must have a Medical Research Council (MRC) dyspnea score \>= 2.

Exclusion criteria:

Subjects who have been treated with maintenance medications for chronic respiratory disease within six months prior to screening.

Subjects with significant diseases other than COPD. Subjects on chronic systemic corticosteroids.

Subjects with any upper and/or lower respiratory tract infection or COPD exacerbation in the 6 weeks prior to the initial visit 1 or during the screening period prior to visit 3 Subjects with a recent (past 6 months) myocardial infarction, any unstable or life threatening cardiac arrhythmia requiring intervention or change in drug therapy during the last year; or who have been hospitalized for cardiac failure during the past year.
D: Inclusion Criteria:

* Adults 40 years and above diagnosed with COPD according to GOLD criteria i.e. Forced expiratory volume in one second (FEV1)/ forced vital capacity (FVC) \< 0.70.
* Needs to understand Swedish or have access to anyone who understands Swedish.

Exclusion Criteria:

* Not COPD

Answer: A