Please select the eligibility criteria that correspond to the clinical trial below.
Title: Breast Cancer and Exercise Trial in Alberta: The BETA Trial
Brief Summary: The Breast Cancer and Exercise Trial (BETA Trial) is a randomized controlled trial aimed at understanding what dose (or volume) of exercise will best reduce the risk for breast cancer, particularly among women who are between the ages of 50-74. The primary aim is to compare the effects of a high versus moderate volume exercise intervention on specific biological intermediate endpoints for breast cancer in a group of previously inactive postmenopausal women


Options:
A: Inclusion Criteria:

Community-dwelling older persons aged 65 or above.

Able to walk without help of another person during 2 minutes, and without major physical limitations, defined as a score on the Short Physical Performance Battery (Guralnik et al., 1995) of 4 or above. The use of an assistive device will be permitted.

Insufficiently active and/or Self-report sitting too much during a usual day. Answer yes to the following question: 'Do you perform regular physical activity (PA) at least 30 minutes five or more days of the week (please only refer to physical activity that makes the participant run out of breath while doing it or it doesn't allow him/her to maintain a conversation while doing the activity (do not count regular walking)?'

And/or answer yes to question: 'For most days, do you feel you sit for too long (6-8 hours or more a day)? Some examples might include when watching TV, working the computer / laptop or when doing sitting-based hobbies such as sewing'.

Exclusion Criteria:

Dementia assessed with the six-Item Screener. Participants with three or more errors should be excluded.

Unstable medical conditions (e.g. elevated blood pressure after medication) or with symptomatic cardiovascular disease.

Any medical condition which may interfere with the study design (e.g. end-stage disease).

Refuse to wear an accelerometer (primary outcome)

Unable to attend during the study period (80% of the total sessions).

Had participated in an ERS in the 6 months prior the study.
B: Inclusion Criteria:

* Age: 50- 74 years, postmenopausal women
* No previous cancer diagnosis
* Physically fit to undertake exercise program
* Pass the Physical Activity Readiness
* Medical Exam,acceptable heart and lung function during a sub-maximal treadmill test
* Body mass index : 22 - 40
* Non-users of exogenous hormones or drugs related to estrogen metabolism, breast tissue growth
* Non-Smoker and non-excessive alcohol drinkers
* Residents of Calgary and Edmonton able to attend fitness facility regularly.

Exclusion Criteria:

* \< 50 years of age
* Diabetes
* Deemed too fit or too unfit on sub-maximal treadmill test
* Non English Speaking
* \> 4 consecutive weeks absence during the intervention period
C: Inclusion Criteria:

* BMI between 25-50
* Watch at least 3 hours of TV per day or 21 hours per week.
* Between the ages of 21-65 years.
* Willing to have study staff enter home several times.
* Willing to have TV viewing time reduced.

Exclusion Criteria:

* Live greater than 45 minutes from UVM campus.
* Enrolled in a weight loss study
* Pregnant or planning to become pregnant during active study protocol.
* Breastfeeding for 6 months or less.
D: Inclusion Criteria:

* Adults between 21 and 65 years
* Sedentary (engaging in moderate intensity physical activity for less than 60 minutes per week)
* Working full time (35+ hours/week) at a sedentary desk dependant occupation
* Overweight (Body Mass Index \> 25.0 kg/m2 but less than 40.0 kg/2)
* Apparently healthy as assessed by a health history screening survey
* Devoid of overt complicated or acute cardiovascular, metabolic, respiratory, or neurological diseases
* Free from exercise/physical activity limitations

Exclusion Criteria:

* Adults with significant health problems exacerbated by exercise, such as uncontrolled hypertension, diabetes, orthopedic limitations, etc. will be excluded from the study. Note, with physician approval and adequate control of these health problems, these conditions will not necessarily preclude participation.
* Being unable to exercise

Answer: B