Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Estradiol Metered-Dose Transdermal Spray (MDTS) in the Treatment of Vasomotor Symptoms in Postmenopausal Women
Brief Summary: Estradiol treatment is effective at reducing vasomotor symptoms (eg hot flushes) in postmenopausal women. This study will evaluate the safety and efficacy of Evamist.


Options:
A: Arm Label: Placebo transdermal three 90 μL sprays; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo transdermal three 90 μL sprays | Arm Label: Placebo transdermal two 90 μL sprays; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo transdermal two 90 μL sprays | Arm Label: Placebo transdermal one 90 μL spray; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo transdermal one 90 μL spray | Arm Label: Estradiol transdermal three 90 μL sprays; Type: ACTIVE_COMPARATOR; Interventions: Drug: Estradiol transdermal three 90 μL sprays | Arm Label: Estradiol transdermal two 90 μL sprays; Type: ACTIVE_COMPARATOR; Interventions: Drug: Estradiol transdermal spray, two 90 μL sprays | Arm Label: Estradiol transdermal one 90 μL spray; Type: ACTIVE_COMPARATOR; Interventions: Drug: Estradiol transdermal one 90 μL spray | Intervention Type: DRUG; Name: Estradiol transdermal one 90 μL spray; Assigned to Arm(s): Estradiol transdermal one 90 μL spray | Intervention Type: DRUG; Name: Estradiol transdermal spray, two 90 μL sprays; Assigned to Arm(s): Estradiol transdermal two 90 μL sprays | Intervention Type: DRUG; Name: Estradiol transdermal three 90 μL sprays; Assigned to Arm(s): Estradiol transdermal three 90 μL sprays | Intervention Type: DRUG; Name: Placebo transdermal two 90 μL sprays; Assigned to Arm(s): Placebo transdermal two 90 μL sprays | Intervention Type: DRUG; Name: Placebo transdermal three 90 μL sprays; Assigned to Arm(s): Placebo transdermal three 90 μL sprays | Intervention Type: DRUG; Name: Placebo transdermal one 90 μL spray; Assigned to Arm(s): Placebo transdermal one 90 μL spray
B: Intervention Type: DRUG; Name: estradiol gel; Assigned to Arm(s): N/A
C: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: bioidentical hormone (Biest) | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Drug: bioidentical hormone (Biest) | Arm Label: 3; Type: EXPERIMENTAL; Interventions: Drug: bioidentical hormone (Biest) | Arm Label: 4; Type: EXPERIMENTAL; Interventions: Drug: bioidentical hormone (Vivelle-Dot) | Intervention Type: DRUG; Name: bioidentical hormone (Biest); Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: bioidentical hormone (Biest); Assigned to Arm(s): 2 | Intervention Type: DRUG; Name: bioidentical hormone (Biest); Assigned to Arm(s): 3 | Intervention Type: DRUG; Name: bioidentical hormone (Vivelle-Dot); Assigned to Arm(s): 4
D: Arm Label: Arm 1; Type: ACTIVE_COMPARATOR; Interventions: Drug: Climara PRO (Estradiol / Levonorgestrel transdermal) | Arm Label: Arm 2; Type: ACTIVE_COMPARATOR; Interventions: Drug: Menostar (Estradiol transdermal) | Arm Label: Arm 3; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo transdermal | Intervention Type: DRUG; Name: Climara PRO (Estradiol / Levonorgestrel transdermal); Assigned to Arm(s): Arm 1 | Intervention Type: DRUG; Name: Menostar (Estradiol transdermal); Assigned to Arm(s): Arm 2 | Intervention Type: DRUG; Name: Placebo transdermal; Assigned to Arm(s): Arm 3

Answer: A