Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: BEACOPP (4 Cycles Escalated + 4 Cycles Baseline) Versus ABVD (8 Cycles) In Stage III & IV Hodgkin's Lymphoma
Brief Summary: RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective in treating stage III or stage IV Hodgkin's lymphoma.

PURPOSE: Randomized phase III trial to compare the effectiveness of two combination chemotherapy regimens in treating patients who have stage III or stage IV Hodgkin's lymphoma.


Options:
A: Arm Label: Arm B; Type: EXPERIMENTAL; Interventions: Drug: Bleomycin, Drug: Etoposide, Drug: Doxorubicin, Drug: Cyclophosphamide, Drug: Vincristine, Drug: Procarbazine, Drug: Prednisone | Arm Label: Arm A; Type: ACTIVE_COMPARATOR; Interventions: Drug: Doxorubicin, Drug: Bleomycin, Drug: Vinblastine, Drug: Dacarbazine | Intervention Type: DRUG; Name: Bleomycin; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Etoposide; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Doxorubicin; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Cyclophosphamide; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Vincristine; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Procarbazine; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Prednisone; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Doxorubicin; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: Bleomycin; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: Vinblastine; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: Dacarbazine; Assigned to Arm(s): Arm A
B: Arm Label: Arm I; Type: ACTIVE_COMPARATOR; Interventions: Biological: bleomycin sulfate, Drug: dacarbazine, Drug: doxorubicin hydrochloride, Drug: vinblastine sulfate | Arm Label: Arm II; Type: ACTIVE_COMPARATOR; Interventions: Drug: dacarbazine, Drug: doxorubicin hydrochloride, Drug: vinblastine sulfate | Arm Label: BEACOPP-14 chemotherapy; Type: EXPERIMENTAL; Interventions: Biological: bleomycin sulfate, Biological: filgrastim, Biological: pegfilgrastim, Drug: cyclophosphamide, Drug: doxorubicin hydrochloride, Drug: etoposide, Drug: prednisolone, Drug: procarbazine hydrochloride, Drug: vincristine sulfate | Arm Label: BEACOPP-escalated chemotherapy; Type: EXPERIMENTAL; Interventions: Biological: bleomycin sulfate, Biological: filgrastim, Biological: pegfilgrastim, Drug: cyclophosphamide, Drug: doxorubicin hydrochloride, Drug: etoposide, Drug: prednisolone, Drug: procarbazine hydrochloride, Drug: vincristine sulfate | Intervention Type: BIOLOGICAL; Name: bleomycin sulfate; Assigned to Arm(s): Arm I, BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: BIOLOGICAL; Name: filgrastim; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: BIOLOGICAL; Name: pegfilgrastim; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: cyclophosphamide; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: dacarbazine; Assigned to Arm(s): Arm I, Arm II | Intervention Type: DRUG; Name: doxorubicin hydrochloride; Assigned to Arm(s): Arm I, Arm II, BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: etoposide; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: prednisolone; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: procarbazine hydrochloride; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: vinblastine sulfate; Assigned to Arm(s): Arm I, Arm II | Intervention Type: DRUG; Name: vincristine sulfate; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy
C: Arm Label: ABVD; Type: ACTIVE_COMPARATOR; Interventions: Biological: bleomycin sulfate, Drug: ABVD regimen, Drug: dacarbazine, Drug: doxorubicin hydrochloride, Drug: vinblastine sulfate | Arm Label: BEACOPP; Type: EXPERIMENTAL; Interventions: Biological: bleomycin sulfate, Biological: filgrastim, Biological: pegfilgrastim, Drug: BEACOPP regimen, Drug: cyclophosphamide, Drug: doxorubicin hydrochloride, Drug: etoposide, Drug: prednisone, Drug: procarbazine hydrochloride, Drug: vincristine sulfate | Intervention Type: BIOLOGICAL; Name: bleomycin sulfate; Assigned to Arm(s): ABVD, BEACOPP | Intervention Type: BIOLOGICAL; Name: filgrastim; Assigned to Arm(s): BEACOPP | Intervention Type: BIOLOGICAL; Name: pegfilgrastim; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: ABVD regimen; Assigned to Arm(s): ABVD | Intervention Type: DRUG; Name: BEACOPP regimen; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: cyclophosphamide; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: dacarbazine; Assigned to Arm(s): ABVD | Intervention Type: DRUG; Name: doxorubicin hydrochloride; Assigned to Arm(s): ABVD, BEACOPP | Intervention Type: DRUG; Name: etoposide; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: prednisone; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: procarbazine hydrochloride; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: vinblastine sulfate; Assigned to Arm(s): ABVD | Intervention Type: DRUG; Name: vincristine sulfate; Assigned to Arm(s): BEACOPP
D: Intervention Type: BIOLOGICAL; Name: bleomycin sulfate; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: doxorubicin hydrochloride; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: mechlorethamine hydrochloride; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: prednisone; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: procarbazine hydrochloride; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: vinblastine sulfate; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: vincristine sulfate; Assigned to Arm(s): N/A | Intervention Type: RADIATION; Name: radiation therapy; Assigned to Arm(s): N/A

Answer: C