Please select the eligibility criteria that correspond to the clinical trial below.
Title: Monitoring Adherence Using Mobile Technology
Brief Summary: This study plans to learn more about how children use their asthma medicines. The investigators would like to see if special electronic monitoring devices that connect to smartphones and computers can help children to better manage their asthma


Options:
A: Inclusion Criteria:

* age 6-17 years and their parents
* either 2 emergency department visits/prednisone bursts in the last 12 months or at least 1 asthma related hospitalization in the last 12 months
* requiring daily controller therapy with either inhaled corticosteroids or combination corticosteroids/long acting beta agonist (LABA).
* Patients using metered dose inhaler therapy would be eligible. Patients may also be on leukotriene antagonists,
* Must be made aware that they will have to read and accept to the terms of the User Agreement prior to enrollment in the study. If they do not agree they will not be able to continue participation. The User agreement will be read agreed to electronically when they begin using the device, however a paper version will be provided at the time of consent upon request.

Exclusion Criteria:

* Primary language other than English or Spanish
* Presence of other significant chronic lung disease including cystic fibrosis, interstitial lung disease, tracheostomy status.
* Patients using diskus therapy.
* Patients only on leukotriene antagonists.
B: Inclusion Criteria:

* provider-diagnosed persistent asthma
* prescription of an ICS in accordance in NHLBI Expert Panel Report 3 guidelines for at least 30 days prior to enrollment
* Asthma Control Test (ACT) score less than 20 (indicating lack of current control)
* no provider-diagnosed exacerbation in the 30 days prior to enrollment
* possession of a text-enabled cell phone and a plan to keep it throughout the study period
* agreement by parents (or participants over 18 years old) to any charges levied by their cell phone carrier for text messages associated with the study if they do not have an unlimited texting plan
* speak and read English

Exclusion Criteria:

* another chronic lung disease (which would complicate measurement of asthma control)
* cognitive or psychiatric disorder that the treating clinician judges would impair study participation
* use of Advair diskus for their ICS (for which no reliable electronic monitor exists)
* current enrollment in another asthma intervention study
C: Inclusion Criteria:

* Patients prescribed therapy equivalent to step 3 or higher on the Asthma Management Guidelines for at least 3 months
* At least one exacerbation in the previous year with systemic glucocorticoids
* Uncontrolled/Partially Controlled Asthma by GINA guidelines

Exclusion Criteria:

* Allergy to salmeterol/fluticasone
* Patients Controlled by GINA guidelines
D: Inclusion Criteria:

Only individuals with persistent asthma will be considered for this study. These definitions are made based on definitions from the National Committee for Quality Assurance (NCQA) and include individuals who meet either criteria A or B:

* A: (Four or more prescription medications used for asthma treatment in 1 year) OR (One or more visits to the emergency room with a principal diagnosis of asthma in 1 year) OR (One or more inpatient hospital visits with a principal diagnosis of asthma in 1 year)
* B: (Four or more outpatient visits with any diagnosis of asthma) AND (two or more claims for a prescription drug used for asthma treatment in 1 year)

Other Inclusion Criteria:

* Speaks and reads English fluently
* Member of Highmark
* Has access to the Internet at home or at work
* Has a valid e-mail address
* No history of more than 20 pack-years of cigarette smoking
* Enrolled in a Highmark health plan offering that includes prescription drug coverage

Exclusion Criteria:

* Does not speak English
* Does not have Internet access at home or work
* Smoked more than 20 pack-years (to exclude possible chronic obstructive pulmonary disease \[COPD\])
* Does not currently have asthma
* Pregnant
* Unwilling to consent

Answer: A