Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: This study is designed to test:

1. in patients with negative positron-emission tomography (PET) after 2 cycles of BEACOPPesc chemotherapy: whether the number of cycles can be reduced without compromising progression free survival (PFS) (2 further cycles vs. 6 further cycles)
2. for patients with positive PET after 2 cycles: whether intensifying BEACOPPesc chemotherapy by adding Rituximab improves PFS.


Options:
A: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Drug: Adriamycin, Drug: Bleomycin, Drug: Vinblastine, Drug: DTIC, Radiation: radiation therapy | Arm Label: C; Type: EXPERIMENTAL; Interventions: Drug: Adriamycin, Drug: Bleomycin, Drug: Etoposide, Drug: Procarbazine, Drug: Prednisone, Drug: Vincristine, Radiation: radiation therapy | Arm Label: B; Type: EXPERIMENTAL; Interventions: Drug: Adriamycin, Drug: Bleomycin, Drug: Vinblastine, Drug: DTIC, Radiation: radiation therapy | Arm Label: D; Type: EXPERIMENTAL; Interventions: Drug: Adriamycin, Drug: Bleomycin, Drug: Etoposide, Drug: Procarbazine, Drug: Prednisone, Drug: Vincristine, Radiation: radiation therapy | Intervention Type: DRUG; Name: Adriamycin; Assigned to Arm(s): A, B, C, D | Intervention Type: DRUG; Name: Bleomycin; Assigned to Arm(s): A, B, C, D | Intervention Type: DRUG; Name: Vinblastine; Assigned to Arm(s): A, B | Intervention Type: DRUG; Name: DTIC; Assigned to Arm(s): A, B | Intervention Type: DRUG; Name: Etoposide; Assigned to Arm(s): C, D | Intervention Type: DRUG; Name: Procarbazine; Assigned to Arm(s): C, D | Intervention Type: DRUG; Name: Prednisone; Assigned to Arm(s): C, D | Intervention Type: DRUG; Name: Vincristine; Assigned to Arm(s): C, D | Intervention Type: RADIATION; Name: radiation therapy; Assigned to Arm(s): A, B, C, D
B: Arm Label: ABVD; Type: ACTIVE_COMPARATOR; Interventions: Biological: bleomycin sulfate, Drug: ABVD regimen, Drug: dacarbazine, Drug: doxorubicin hydrochloride, Drug: vinblastine sulfate | Arm Label: BEACOPP; Type: EXPERIMENTAL; Interventions: Biological: bleomycin sulfate, Biological: filgrastim, Biological: pegfilgrastim, Drug: BEACOPP regimen, Drug: cyclophosphamide, Drug: doxorubicin hydrochloride, Drug: etoposide, Drug: prednisone, Drug: procarbazine hydrochloride, Drug: vincristine sulfate | Intervention Type: BIOLOGICAL; Name: bleomycin sulfate; Assigned to Arm(s): ABVD, BEACOPP | Intervention Type: BIOLOGICAL; Name: filgrastim; Assigned to Arm(s): BEACOPP | Intervention Type: BIOLOGICAL; Name: pegfilgrastim; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: ABVD regimen; Assigned to Arm(s): ABVD | Intervention Type: DRUG; Name: BEACOPP regimen; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: cyclophosphamide; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: dacarbazine; Assigned to Arm(s): ABVD | Intervention Type: DRUG; Name: doxorubicin hydrochloride; Assigned to Arm(s): ABVD, BEACOPP | Intervention Type: DRUG; Name: etoposide; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: prednisone; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: procarbazine hydrochloride; Assigned to Arm(s): BEACOPP | Intervention Type: DRUG; Name: vinblastine sulfate; Assigned to Arm(s): ABVD | Intervention Type: DRUG; Name: vincristine sulfate; Assigned to Arm(s): BEACOPP
C: Arm Label: Arm B; Type: EXPERIMENTAL; Interventions: Drug: Bleomycin, Drug: Etoposide, Drug: Doxorubicin, Drug: Cyclophosphamide, Drug: Vincristine, Drug: Procarbazine, Drug: Prednisone | Arm Label: Arm A; Type: ACTIVE_COMPARATOR; Interventions: Drug: Doxorubicin, Drug: Bleomycin, Drug: Vinblastine, Drug: Dacarbazine | Intervention Type: DRUG; Name: Bleomycin; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Etoposide; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Doxorubicin; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Cyclophosphamide; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Vincristine; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Procarbazine; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Prednisone; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Doxorubicin; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: Bleomycin; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: Vinblastine; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: Dacarbazine; Assigned to Arm(s): Arm A
D: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Drug: BEACOPP escalated | Arm Label: B; Type: EXPERIMENTAL; Interventions: Drug: Rituximab, Drug: BEACOPP escalated | Arm Label: C; Type: ACTIVE_COMPARATOR; Interventions: Drug: BEACOPP escalated | Arm Label: D; Type: EXPERIMENTAL; Interventions: Drug: BEACOPP escalated | Intervention Type: DRUG; Name: Rituximab; Assigned to Arm(s): B | Intervention Type: DRUG; Name: BEACOPP escalated; Assigned to Arm(s): A, B, C, D

Answer: D