Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Randomized, Double-blind, Placebo-controlled, Multicenter Study Comparing Ciprofloxacin DPI 32.5 mg BID (Twice a Day) Intermittently Administered for 28 Days on / 28 Days Off or 14 Days on / 14 Days Off Versus Placebo to Evaluate the Time to First Pulmonary Exacerbation and Frequency of Exacerbations in Subjects With Non-Cystic Fibrosis Bronchiectasis.
Brief Summary: The purpose of this study is to evaluate if the time to first pulmonary exacerbation of bronchiectasis or its frequency can be prolonged by inhalation of ciprofloxacin for 28 days every other 28 days or for 14 days every other 14 days over 48 weeks.


Options:
A: Arm Label: Ciprofloxacin DPI 28 Days on/off (Cipro 28); Type: EXPERIMENTAL; Interventions: Drug: Ciprofloxacin (BAYQ3939) dry powder for inhalation | Arm Label: Ciprofloxacin DPI 14 Days on/off (Cipro 14); Type: EXPERIMENTAL; Interventions: Drug: Ciprofloxacin (BAYQ3939) dry powder for inhalation | Arm Label: Placebo 28 Days on/off (Placebo 28); Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: Placebo 14 Days on/off (Placebo 14); Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Ciprofloxacin (BAYQ3939) dry powder for inhalation; Assigned to Arm(s): Ciprofloxacin DPI 28 Days on/off (Cipro 28) | Intervention Type: DRUG; Name: Ciprofloxacin (BAYQ3939) dry powder for inhalation; Assigned to Arm(s): Ciprofloxacin DPI 14 Days on/off (Cipro 14) | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo 28 Days on/off (Placebo 28) | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo 14 Days on/off (Placebo 14)
B: Arm Label: Ciprofloxacin dispersion for inhalation; Type: EXPERIMENTAL; Interventions: Drug: Ciprofloxacin dispersion for inhalation | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Ciprofloxacin dispersion for inhalation; Assigned to Arm(s): Ciprofloxacin dispersion for inhalation | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
C: Arm Label: Cohort A (3 capsules o.d.): TIP; Type: EXPERIMENTAL; Interventions: Drug: TIP | Arm Label: Cohort A (3 capsules o.d.): TIP/PBO; Type: EXPERIMENTAL; Interventions: Drug: TIP and placebo | Arm Label: Cohort A (3 capsules o.d.): PBO; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: Cohort B (5 capsules o.d.): TIP; Type: EXPERIMENTAL; Interventions: Drug: TIP | Arm Label: Cohort B (5 capsules o.d.): TIP/PBO; Type: EXPERIMENTAL; Interventions: Drug: TIP and placebo | Arm Label: Cohort B (5 capsules o.d.): PBO; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: Cohort C (4 capsules b.i.d.): TIP; Type: EXPERIMENTAL; Interventions: Drug: TIP | Arm Label: Cohort C (4 capsules b.i.d.): TIP/PBO; Type: EXPERIMENTAL; Interventions: Drug: TIP and placebo | Arm Label: Cohort C (4 capsules b.i.d.): PBO; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: TIP; Assigned to Arm(s): Cohort A (3 capsules o.d.): TIP, Cohort B (5 capsules o.d.): TIP, Cohort C (4 capsules b.i.d.): TIP | Intervention Type: DRUG; Name: TIP and placebo; Assigned to Arm(s): Cohort A (3 capsules o.d.): TIP/PBO, Cohort B (5 capsules o.d.): TIP/PBO, Cohort C (4 capsules b.i.d.): TIP/PBO | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Cohort A (3 capsules o.d.): PBO, Cohort B (5 capsules o.d.): PBO, Cohort C (4 capsules b.i.d.): PBO
D: Arm Label: Ciprofloxacin dispersion for inhalation; Type: EXPERIMENTAL; Interventions: Drug: Ciprofloxacin dispersion for inhalation | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Ciprofloxacin dispersion for inhalation; Assigned to Arm(s): Ciprofloxacin dispersion for inhalation | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo

Answer: A