Please select the eligibility criteria that correspond to the clinical trial below.
Title: Impact of Cardiovascular Rehabilitation on the Quality of Life of Adolescents and Young Adults With Congenital Heart Disease: A Randomized Controlled Multicentre Trial
Brief Summary: The investigators aim to measure the impact of a rehabilitation program in congenital cardiology in terms of health related quality of life. The orginality of the rehabilitation program consists in its design : initial hospitalizationfor a short period of time (5 days) at the rehabilitation center, followed by 11 weeks of rehabilitation at home under the supervision of a specialized sports trainer.


Options:
A: Inclusion Criteria:

1. Between the ages of 18-25 (if 18, must no longer be in high school and no longer living at home)
2. Are diagnosed with moderate or complex structural congenital heart disease
3. Live within 120 miles of Nationwide Children's Hospital

Exclusion Criteria:

1. Do no speak or write proficiently in English
2. Have cognitive impairments that would interfere with the completion of study procedures
3. Are diagnosed with a genetic syndrome (e.g., Downs, Marfans)
4. Have been engaged in a formal exercise program within the past 6 months
5. Underwent open-heart surgery or have had a transcatheter valve replacement in the last 3 months
6. Are otherwise prohibited by their cardiologist to engage in at least moderate levels of physical activity
7. Are unable to complete a treadmill-based exercise stress test
8. Are currently pregnant
9. Have contraindications for exercise based on an exercise stress test (e.g., exercise-induced arrhythmias or evidence of cardiac ischemia)
10. \>150 min/weekday of moderate-to-vigorous physical activity per the accelerometer
11. Do not have access or a device for videoconferencing with the coach
B: Inclusion Criteria:

* Patient aged 13 to 25 years included
* With a congenital heart diseases (CHD) as defined in the international CHD classification.
* Recent (\< 3 months) cardio-pulmonary exercise test (CPET)with maximum oxygen uptake (VO2max) \<80% of theoretical values and/or first ventilatory anaerovic threshold (VAT) \<55% of VO2max.
* Consent of the adult patient or the parents or legal guardians of the minor patient.
* Beneficiary of the social security scheme.

Exclusion Criteria:

* Uncontrolled arrhythmia.
* Cardiac surgery planned during the rehabilitation program.
* Severe musculoskeletal disorders.
* Severe intellectual disability that does not allow the quality of life questionnaire to be completed.
* Pregnancy.
* Patient who already underwent cardiac rehabilitation in the last 24 months.
* All medical contraindications to perform a cardiorespiratory stress test.
* Uncontrolled heart failure (NYHA IV)
* Obesity (BMI \> 30)
C: Inclusion Criteria:

* being diagnosed with CHD by a pediatric cardiologist and qualifying as having simple or moderate CHD complexity according to the 2008 American College of Cardiology/American Heart Association guidelines;
* having a regular pulse;
* being 15-24 years of age;
* being conversant in Mandarin and Taiwanese;
* possessing a smartphone with Internet connection;
* agreeing to wear an exercise-monitoring wristband to record physiological data;
* agreeing to engage in exercises designed to test cardiopulmonary endurance;
* agreeing to participate in the study and sign an informed consent form for a relevant interview. For participants under 20 years of age, guardian approval by signing a written consent form was required.

Exclusion Criteria:

* having cognitive impairment to the extent of being noncommunicative;
* having CHD complicated with other congenital abnormalities;
* having undergone a cardiac catheter-related intervention or surgery within the past 6 months;
* being pregnant
D: Inclusion Criteria:

* Boys and girls ages 10 to 17 years with repaired Tetralogy of Fallot, currently followed at The Hospital for Sick Children, Toronto, Ontario
* Participant fluent in English

Exclusion Criteria:

* Moderate-to-severe ventricular dysfunction at the latest echocardiogram (defined as the qualitative grade given on the echocardiogram done closest to the intervention)
* Previous history of or documented frequent premature atrial or ventricular contractions or runs or associated tachycardia at the latest exercise test
* Reside outside 50km radius from SickKids or \>1hour travel distance to SickKids
* Lack of internet and computer/laptop access
* Skeletal muscle or orthopedic pathologies
* Neurodevelopmental delay that would preclude participation in an exercise program
* History of syncope with exercise
* Planned surgery requiring admission to intensive care unit during the study intervention

Answer: B