Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Age-dependent Effects of Flavanol Metabolism and Absorption on Vascular Status After Acute and Chronic Application.
Brief Summary: Epidemiological studies suggest that certain foods rich in flavanols, including cocoa products, red wine, and tea, are associated with decreased cardiovascular mortality and morbidity. Dietary interventional studies have corroborated this finding and showed that flavanols can acutely and after sustained ingestion improve surrogate markers of cardiovascular risk including endothelial function. Endothelial dysfunction is the key event in the development and progression of cardiovascular disease. Aging is the major non-modifiable cardiovascular risk factor associated with progressive decline in endothelial function, vascular stiffening and increase in blood pressure. We hypothesize that flavanols can counteract age-dependent vascular changes by interacting with key mechanisms, most prominently endothelial function.


Options:
A: Arm Label: Intervention A; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Flavonoid enrichment (cocoa / soy compounds) | Arm Label: Intervention B; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Flavonoid enrichment (cocoa / soy compounds) | Intervention Type: DIETARY_SUPPLEMENT; Name: Flavonoid enrichment (cocoa / soy compounds); Assigned to Arm(s): Intervention A | Intervention Type: DIETARY_SUPPLEMENT; Name: Flavonoid enrichment (cocoa / soy compounds); Assigned to Arm(s): Intervention B
B: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Nestlé Noir intense 40 grx2 | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Nestlé Placebo Chocolate 40 grx2 | Intervention Type: DIETARY_SUPPLEMENT; Name: Nestlé Noir intense 40 grx2; Assigned to Arm(s): 1 | Intervention Type: DIETARY_SUPPLEMENT; Name: Nestlé Placebo Chocolate 40 grx2; Assigned to Arm(s): 2
C: Arm Label: flavanol rich intervention; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Flavanol rich intervention | Arm Label: flavanol free intervention; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Flavanol free control | Intervention Type: DIETARY_SUPPLEMENT; Name: Flavanol rich intervention; Assigned to Arm(s): flavanol rich intervention | Intervention Type: DIETARY_SUPPLEMENT; Name: Flavanol free control; Assigned to Arm(s): flavanol free intervention
D: Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Other: Control breakfast, Other: High glycemic index breakfast, Other: Low glycemic index breakfast | Arm Label: Intervention 1; Type: EXPERIMENTAL; Interventions: Other: Control breakfast, Other: High glycemic index breakfast, Other: Low glycemic index breakfast | Arm Label: Intervention 2; Type: EXPERIMENTAL; Interventions: Other: Control breakfast, Other: High glycemic index breakfast, Other: Low glycemic index breakfast | Intervention Type: OTHER; Name: Control breakfast; Assigned to Arm(s): Control, Intervention 1, Intervention 2 | Intervention Type: OTHER; Name: High glycemic index breakfast; Assigned to Arm(s): Control, Intervention 1, Intervention 2 | Intervention Type: OTHER; Name: Low glycemic index breakfast; Assigned to Arm(s): Control, Intervention 1, Intervention 2

Answer: C