Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Development and Evaluation of a Diabetes-specific Cognitive Behavioural Treatment (DS-CBT) for Diabetic Patients With Subthreshold Depression
Brief Summary: This work is supported by the "Kompetenznetz Diabetes mellitus (Competence Network for Diabetes mellitus)" funded by the Federal Ministry of Education and Research (FKZ 01GI0809).

Approximately one third of diabetic patients has elevated depressive symptoms. The majority of these patients are suffering from a subthreshold depression. In spite of the fact that subthreshold depression has an equivalent negative impact on the prognosis of diabetes as clinical depression, there is no specific intervention tool. The main objective of this project is to develop a diabetes specific cognitive behavioural treatment (DS-CBT) for diabetic patients with subthreshold depression. In a randomized trail DS-CBT is compared to standard diabetes education. A total of 188 diabetic patients will be recruited and randomly assigned to the two treatment conditions. The expected main outcome is the reduction of subthreshold depression under DS-CBT in a 12 month follow up. Secondary variables are improvement of glycaemic control, quality of life, diabetes self-management as well as reduction of health care costs and modification of inflammatory parameters.


Options:
A: Arm Label: Diabetes-Specific CBT (DS-CBT); Type: EXPERIMENTAL; Interventions: Behavioral: Diabetes-Specific CBT (DS-CBT) | Arm Label: Standard Diabetes Education; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Standard Diabetes Education | Intervention Type: BEHAVIORAL; Name: Diabetes-Specific CBT (DS-CBT); Assigned to Arm(s): Diabetes-Specific CBT (DS-CBT) | Intervention Type: BEHAVIORAL; Name: Standard Diabetes Education; Assigned to Arm(s): Standard Diabetes Education
B: Arm Label: Deprexis; Type: EXPERIMENTAL; Interventions: Behavioral: Deprexis | Arm Label: Wait-list; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Deprexis, Behavioral: Wait-list | Intervention Type: BEHAVIORAL; Name: Deprexis; Assigned to Arm(s): Deprexis, Wait-list | Intervention Type: BEHAVIORAL; Name: Wait-list; Assigned to Arm(s): Wait-list
C: Arm Label: SSRI + placebo; Type: ACTIVE_COMPARATOR; Interventions: Drug: SSRI + placebo | Arm Label: Escitalopram + Bupropion SR; Type: ACTIVE_COMPARATOR; Interventions: Drug: Escitalopram + Bupropion SR | Arm Label: Venlafaxine XR + Mirtazapine; Type: ACTIVE_COMPARATOR; Interventions: Drug: Venlafaxine XR + Mirtazapine | Intervention Type: DRUG; Name: SSRI + placebo; Assigned to Arm(s): SSRI + placebo | Intervention Type: DRUG; Name: Escitalopram + Bupropion SR; Assigned to Arm(s): Escitalopram + Bupropion SR | Intervention Type: DRUG; Name: Venlafaxine XR + Mirtazapine; Assigned to Arm(s): Venlafaxine XR + Mirtazapine
D: Arm Label: Nurse case management and self-management support; Type: EXPERIMENTAL; Interventions: Other: Nurse case management and self-management support | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Nurse case management and self-management support; Assigned to Arm(s): Nurse case management and self-management support

Answer: A