Please select the eligibility criteria that correspond to the clinical trial below.
Title: REVITIVE for the Treatment of Patients With Venous Insufficiency
Brief Summary: To investigate the efficacy of an electrical stimulation (using the REVITIVE IX device) in treating patients with venous insufficiency.


Options:
A: Inclusion Criteria:

* Ability to understand the study and provide meaningful written informed consent for the study.
* Willing, able, and committed to participate in the procedures for the full length of the study.
* All ethnic groups, male or female above the age of 18 years.
* Diagnosis of chronic venous insufficiency (C2-C5 CEAP classified)
* Be of non-childbearing potential; or using adequate contraception and have a negative urine pregnancy test result within 24 hours if appropriate before using the device.
* Blood pressure currently under moderate control (\<160/100mmHg)
* No current foot ulceration.

Exclusion Criteria:

* Has insufficient ability to understand the subject information sheet, consent form and verbal instruction.
* Has an unstable condition (eg psychiatric disorder, a recent history of substance abuse or otherwise thought to be unreliable or incapable of complying wight he requirements of the clinical investigational plan (CIP).
* Has any metal implants.
* Pregnant.
* Has a cardiac pacemaker, AICD or other implanted electrical device.
* Has an existing DVT.
* Has an acute medical condition other than chronic venous insufficiency.
* Has recent lower limb injury or lower back pain.
* Has current foot ulceration or other skin ulcers.
* Has cardiovascular disease.
* Has foot deformities.
* Has any disorder that, in the opinion of the investigator, might interfere with the conduct of the study.
* Has an ABPI \< 0.8.
B: Inclusion Criteria:

* Diagnosis of venous insufficiency between 18-75 years with duplex ultrasound imaging
* CEAP classification used in venous insufficiency is C2-C3-C4-C5
* Having written and verbal communication in Turkish

Exclusion Criteria:

* Acute deep vein thrombosis
* The presence of ulceration
* Being in class III and IV according to the New York Heart Association classification
* Presence of respiratory failure
* Undergoing chemotherapy due to the presence of any cancer
* Being in the process of treatment for neurological, orthopedic or rheumatologic diseases including lower extremity
C: Inclusion Criteria:

* A radiologically confirmed, acute, proximal first lower extremity DVT
* 4 to 8 weeks after starting anticoagulation
* Out-patient ambulatory status

Exclusion Criteria:

* Contraindication to increasing activity such as patients with juvenile arthritis, poor balance, congestive heart failure, etc.
D: Inclusion Criteria:

* patients aged 18 to 80 years with chronic venous insufficiency regardless of etiology stages 3 or 4 according to the CEAP classification (Clinical severity, Etiology or cause, Anatomy, Pathophysiology)
* Patients available to participate in a 3 weeks session in the spa center and to be followed for 6 months

Exclusion Criteria:

* pregnant women,
* contra-indication for the spa treatment (chronic infectious diseases, cancer, heart failure, serious liver or kidney disease, open leg ulcer, psychiatric disorders, immune deficiency, phlebitis, erysipelas or history of erysipelas);
* surgery in the next three months,
* spa treatment in the previous 6 months,
* professional involvement with a spa resort

Answer: A