Please select the eligibility criteria that correspond to the clinical trial below.
Title: Optimizing Sedentary Behavior Interventions to Affect Acute Physiological
Brief Summary: An emerging body of epidemiological evidence suggests that various forms of sedentary behavior, including TV viewing, occupational sitting, and total daily sitting, may be associated with all-cause and cardiovascular mortality, overweight and obesity, type 2 diabetes, depression and psychological well-being. Importantly, many of these associations were independent of participation in moderate to vigorous intensity physical activity. We propose a pilot study to assess the feasibility, acceptability and preliminary efficacy of two interventions targeting sedentary behavior. Since it is currently unknown what component of sedentary behavior exposure presents the greatest risk to health, we propose separate interventions to reduce overall sedentary time and to promote breaks in sedentary time.


Options:
A: Inclusion Criteria:

* Mostly sedentary (sitting ≥ 4 hour) during the workday.
* Age ≥ 18
* Anticipated using a single computer workstation for 20 hours or more per week

Exclusion Criteria:

* Unable to stand for at least two hours per workday (two hours over the whole workday, not consecutively)
* Reported severe musculoskeletal symptoms, specifically lower extremity or lower back pain.
* Diagnosed with or under treatment for diabetes, heart disease, cancer, orthostatic hypertension, varicose vein, autoimmune disease, or other chronic diseases.
* Pregnant women
B: Inclusion Criteria:

* Adults between 21 and 65 years
* Sedentary (engaging in moderate intensity physical activity for less than 60 minutes per week)
* Working full time (35+ hours/week) at a sedentary desk dependant occupation
* Overweight (Body Mass Index \> 25.0 kg/m2 but less than 40.0 kg/2)
* Apparently healthy as assessed by a health history screening survey
* Devoid of overt complicated or acute cardiovascular, metabolic, respiratory, or neurological diseases
* Free from exercise/physical activity limitations

Exclusion Criteria:

* Adults with significant health problems exacerbated by exercise, such as uncontrolled hypertension, diabetes, orthopedic limitations, etc. will be excluded from the study. Note, with physician approval and adequate control of these health problems, these conditions will not necessarily preclude participation.
* Being unable to exercise
C: Inclusion Criteria:

Worksite-level inclusion criteria:

* Size: Small to moderate size worksite (20-60 employees)
* Schedule: \>80% of employees full time
* Occupation: Seated office work, primarily computer- and- telephone-based work, little movement or walking
* Wellness environment: Not currently undergoing a wellness program aimed at increasing activity at work
* Workstations: Willing to have sit-stand workstations installed at a worksite
* Willing to be randomized: Willing to be randomized to either intervention conditions

Member-level inclusion criteria:

* Age: 18 years and older
* Health status: Generally good health and able to safely increase LPA and reduce sitting time
* Employment status: Any sedentary job, sitting most of the say, little standing or walking
* Occupation: Traditional sitting desk, willing to have a sit-stand workstation installed at desk
* Workstation: traditional sitting desk;willing to have a sit-stand workstation installed at desk

Exclusion Criteria:

* contraindication to prolonged standing at work
D: Inclusion Criteria:

1. Males or females 50 -70 years of age
2. Able to attend 4 measurement visits with study staff in 3 consecutive weeks
3. Spend at least 8 hours per day sitting
4. Willing and able to wear study device for 21 days
5. Able to read and write in English
6. Able to provide written informed consent

Exclusion Criteria:

1. Do not sit for at least 8 hours per day
2. Unable to attend 4 visits
3. Diagnosis of serious chronic condition that would limit the ability to stand

Answer: D