Please select the eligibility criteria that correspond to the clinical trial below.
Title: Filipinos Fit and Trim Weight Loss for Diabetes Prevention Program
Brief Summary: Filipino Americans (FA) are the second largest (3.4 million) Asian group in the US. and have one of the highest prevalences of obesity and type 2 diabetes mellitus compared to non-Hispanic whites, African Americans and Hispanics. However, FA have been underrepresented in health related research, particularly in diabetes prevention. This proposed pilot study is the first clinical trial to assess preliminary estimates of the short-term effect of the novel social networking diabetes prevention program lifestyle intervention for this high-risk population.


Options:
A: Inclusion Criteria:

* Age: 18 - 65 years
* BMI: 30,0 - 39,9 kg/m2
* Owner of a smartphone
* Caucasian
* No severe diseases
* Informed written consent

Exclusion Criteria:

* Diabetes mellitus
* Severe cardiovascular and/or respiratory disease
* Untreated high blood pressure
* Severe kidney disease
* Active cancer (or in remission)
* Inflammatory bowel disease
* Severe chronic infections and/or inflammations
* Severe mental-health disorders
* Neurodegenerative disorders
* Endocrine diseases
* Lipedema
* Pregnancy and lactation
* Vigorous weight fluctuations (\> 5 kg) in the last 3 months
* Immobility
* Surgery in the last 3 months
* Participation in other intervention studies
* Carrier of pace makers
* Blood donation or transfusion in the last 3 months
B: Inclusion Criteria:: 1) BMI for Asians \> 23 kg/m2, 2) Age \> 24 years, 3) Diabetes risk test score52 \> 5 points, fasting plasma glucose test between 100 - 125 mg/dl, HbA1c \> 5.6% or oral glucose tolerance test (OGTT) between 140-200 mg/dl, 4) physically inactive based on Brief Physical Activity Recall Questionnaire,53 5) no cognitive impairment based on the Mini-Cog test,54 and 7) English speaking. Only one member per household will be allowed to enroll in the study. A smart phone will be provided if necessary.

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Exclusion Criteria:1) Physician diagnosed diabetes and confirmed by clinical data (e.g. documentation of fasting blood glucose \>126 mg/dL or a positive OGTT), 2) HbA1C \> 7.0%, 3) Glucose metabolism associated disease (Cushing's syndrome, Acromegaly, and Pheochromocytoma currently under treatment, chronic pancreatitis), 4) Thyroid disease - sub-optimally treated, 5) Known medical conditions or other physical problems needing special exercise program (e.g., prior myocardial infarction, history of angioplasty or angina, admission for hospital evaluation of chest pain, use of nitroglycerin for angina, asthma, chronic obstructive pulmonary disease, or uncontrolled hypertension), 6) Currently participating in a lifestyle modification program, 7) Planning a trip outside of the US during the 3-month study period, 8) Known eating disorder, 9) Planning to have gastric bypass surgery, 10) Taking antibiotics (including HIV-related agents), anti-tuberculosis agents (except tuberculosis prophylaxis)\], or prescription weight-loss drugs.

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C: Inclusion Criteria:

* child aged between 12.0 and 17.0 years,
* child BMI =/\> 98th percentile,
* first language is English (or fluent in English)
* parent/s willing to participate in the programme with their child
* completion of written informed consent and/or assent prior to any study-specific procedures

Exclusion Criteria:

* severe intellectual difficulties,
* obesity secondary to genetic condition,
* limitations to engaging in physical activity
* use of medication known to effect body weight;
* limitations to using a smartphone device
* known family issues that would affect general compliance and attendance at follow-up visits.
D: Inclusion Criteria:

* BMI\> = 25 mg / kg
* Holder smartphone
* Sign informed consent

Exclusion Criteria:

* Presence of physical or mental illnesses that prevent the realization of physical activity
* Be participating in another research project
* Pregnancy or lactation
* Patients who are on diet or drug treatment for weight loss
* History of myocardial infarction or stroke

Answer: B