TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Community-based Rehabilitation Training After Stroke: a Pilot Randomised Controlled Trial
Brief Summary: A pilot study that will evaluate the feasibility and acceptability of procedures to inform the design and delivery of a definitive RCT of ReTrain (which would assess the clinical and cost effectiveness of ReTrain for stroke survivors).


Options:
A: Intervention Type: OTHER; Name: Visumotor Upper Extremity Training; Assigned to Arm(s): N/A | Intervention Type: OTHER; Name: Anodal/Sham tDCS; Assigned to Arm(s): N/A
B: Arm Label: real tDCS; Type: EXPERIMENTAL; Interventions: Device: tDCS | Arm Label: sham tDCS; Type: SHAM_COMPARATOR; Interventions: Device: tDCS | Arm Label: no stimulation; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: tDCS; Assigned to Arm(s): real tDCS, sham tDCS
C: Arm Label: real-tDCS with MI-BCI; Type: ACTIVE_COMPARATOR; Interventions: Device: real-tDCS with MI-BCI | Arm Label: sham-tDCS with MI-BCI; Type: SHAM_COMPARATOR; Interventions: Device: real-tDCS with MI-BCI | Intervention Type: DEVICE; Name: real-tDCS with MI-BCI; Assigned to Arm(s): real-tDCS with MI-BCI, sham-tDCS with MI-BCI
D: Arm Label: Rehabilitation training; Type: EXPERIMENTAL; Interventions: Other: Rehabilitation | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Rehabilitation; Assigned to Arm(s): Rehabilitation training

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Community-based Rehabilitation Training After Stroke: a Pilot Randomised Controlled Trial
Brief Summary: A pilot study that will evaluate the feasibility and acceptability of procedures to inform the design and delivery of a definitive RCT of ReTrain (which would assess the clinical and cost effectiveness of ReTrain for stroke survivors).


Options:
A: Arm Label: OPC-Stroke, Usual care; Type: EXPERIMENTAL; Interventions: Other: OPC-Stroke, Other: Usual care | Arm Label: Usual care; Type: OTHER; Interventions: Other: Usual care | Intervention Type: OTHER; Name: OPC-Stroke; Assigned to Arm(s): OPC-Stroke, Usual care | Intervention Type: OTHER; Name: Usual care; Assigned to Arm(s): OPC-Stroke, Usual care, Usual care
B: Arm Label: APT-II group; Type: EXPERIMENTAL; Interventions: Behavioral: Attention Process Training-II | Arm Label: standard care group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Attention Process Training-II; Assigned to Arm(s): APT-II group
C: Arm Label: Guttmann, NeuroPersonalTrainer; Type: EXPERIMENTAL; Interventions: Other: Guttmann, NeuroPersonalTrainer | Arm Label: Ictus.online; Type: SHAM_COMPARATOR; Interventions: Other: Ictus.online | Intervention Type: OTHER; Name: Guttmann, NeuroPersonalTrainer; Assigned to Arm(s): Guttmann, NeuroPersonalTrainer | Intervention Type: OTHER; Name: Ictus.online; Assigned to Arm(s): Ictus.online
D: Arm Label: Rehabilitation training; Type: EXPERIMENTAL; Interventions: Other: Rehabilitation | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Rehabilitation; Assigned to Arm(s): Rehabilitation training

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Community-based Rehabilitation Training After Stroke: a Pilot Randomised Controlled Trial
Brief Summary: A pilot study that will evaluate the feasibility and acceptability of procedures to inform the design and delivery of a definitive RCT of ReTrain (which would assess the clinical and cost effectiveness of ReTrain for stroke survivors).


Options:
A: Arm Label: Stroke Management Program (SMP); Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Stroke Management Program (SMP) | Arm Label: Stroke Monitoring Program (SMonP); Type: EXPERIMENTAL; Interventions: Behavioral: Stroke Monitoring Program (SMonP) | Arm Label: Stroke Supplementary Program (SSP); Type: EXPERIMENTAL; Interventions: Behavioral: Stroke Supplementary Program (SSP) | Intervention Type: BEHAVIORAL; Name: Stroke Management Program (SMP); Assigned to Arm(s): Stroke Management Program (SMP) | Intervention Type: BEHAVIORAL; Name: Stroke Monitoring Program (SMonP); Assigned to Arm(s): Stroke Monitoring Program (SMonP) | Intervention Type: BEHAVIORAL; Name: Stroke Supplementary Program (SSP); Assigned to Arm(s): Stroke Supplementary Program (SSP)
B: Arm Label: Cognitive training group; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Cognitive training | Arm Label: Aerobic exercise training group; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Aerobic exercise training | Arm Label: Sequential training group; Type: EXPERIMENTAL; Interventions: Behavioral: Sequential combination of aerobic exercise and cognitive training | Intervention Type: BEHAVIORAL; Name: Cognitive training; Assigned to Arm(s): Cognitive training group | Intervention Type: BEHAVIORAL; Name: Aerobic exercise training; Assigned to Arm(s): Aerobic exercise training group | Intervention Type: BEHAVIORAL; Name: Sequential combination of aerobic exercise and cognitive training; Assigned to Arm(s): Sequential training group
C: Arm Label: Rehabilitation training; Type: EXPERIMENTAL; Interventions: Other: Rehabilitation | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Rehabilitation; Assigned to Arm(s): Rehabilitation training
D: Arm Label: Fit For Function Program; Type: EXPERIMENTAL; Interventions: Other: Fit For Function Program | Arm Label: Standard YMCA membership; Type: ACTIVE_COMPARATOR; Interventions: Other: Standard YMCA membership | Intervention Type: OTHER; Name: Fit For Function Program; Assigned to Arm(s): Fit For Function Program | Intervention Type: OTHER; Name: Standard YMCA membership; Assigned to Arm(s): Standard YMCA membership

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Preparing Family Caregivers of Very Ill Patients for End-of-Life Decision Making
Brief Summary: The overarching goal of the project is to improve the process and experience of surrogate decision-making by family caregivers. Since feeling unprepared to make surrogate decisions is a major contributor to caregiver stress, the primary outcome is caregiver self-efficacy --i.e., caregivers' assessment of how well prepared they feel to serve effectively as a surrogate decision-maker. Through follow-on Renewal funding, we are now also qualitatively examining family caregivers' experience with surrogate decision-making.


Options:
A: Arm Label: SCC1--high intensity supervision; Type: EXPERIMENTAL; Interventions: Behavioral: safer conception counseling | Arm Label: SCC2-- low intensity supervision; Type: EXPERIMENTAL; Interventions: Behavioral: safer conception counseling | Arm Label: Usual care family planning services; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: safer conception counseling; Assigned to Arm(s): SCC1--high intensity supervision, SCC2-- low intensity supervision
B: Arm Label: Standard ACP/Patient Alone; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Standard advance care planning | Arm Label: Decision Aid/Patient Alone; Type: EXPERIMENTAL; Interventions: Behavioral: Making Your Wishes Known | Arm Label: Standard ACP/Together; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Standard advance care planning | Arm Label: Decision Aid/Together; Type: EXPERIMENTAL; Interventions: Behavioral: Making Your Wishes Known | Intervention Type: BEHAVIORAL; Name: Making Your Wishes Known; Assigned to Arm(s): Decision Aid/Patient Alone, Decision Aid/Together | Intervention Type: BEHAVIORAL; Name: Standard advance care planning; Assigned to Arm(s): Standard ACP/Patient Alone, Standard ACP/Together
C: Arm Label: Contraceptive Decision Support Tool; Type: EXPERIMENTAL; Interventions: Behavioral: Contraceptive Decision Support Tool | Arm Label: Usual Care (Control); Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Contraceptive Decision Support Tool; Assigned to Arm(s): Contraceptive Decision Support Tool
D: Arm Label: Patient decision aids; Type: EXPERIMENTAL; Interventions: Other: Patient decision aid | Arm Label: Usual care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Patient decision aid; Assigned to Arm(s): Patient decision aids

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: Purpose: to investigate the postoperative outcomes of Retrograde intrarenal surgery versus percutaneous nephrolithotomy in 2 to 4 cm kidney stones.


Options:
A: Arm Label: Microperc surgery; Type: EXPERIMENTAL; Interventions: Procedure: Microperc surgery | Arm Label: FURS; Type: ACTIVE_COMPARATOR; Interventions: Procedure: FURS | Intervention Type: PROCEDURE; Name: Microperc surgery; Assigned to Arm(s): Microperc surgery | Intervention Type: PROCEDURE; Name: FURS; Assigned to Arm(s): FURS
B: Arm Label: RIRS; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Retrograde intrarenal surgery | Arm Label: PCNL; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Percutaneous nephrolithotomy | Intervention Type: PROCEDURE; Name: Percutaneous nephrolithotomy; Assigned to Arm(s): PCNL | Intervention Type: PROCEDURE; Name: Retrograde intrarenal surgery; Assigned to Arm(s): RIRS
C: Arm Label: RIRS (retrograde intrarenal surgery); Type: EXPERIMENTAL; Interventions: Procedure: RIRS, Device: Rigid and flexible ureteroscope, Device: Holmium laser, Device: Basket for fragment removal, Procedure: General or spinal anesthesia, Device: X-ray | Arm Label: ESWL (extracorporeal shockwaves lithotripsy); Type: EXPERIMENTAL; Interventions: Procedure: ESWL, Device: Lithotripter, Drug: Intravenous pain medication, Device: X-ray, Device: Ultrasound | Intervention Type: PROCEDURE; Name: RIRS; Assigned to Arm(s): RIRS (retrograde intrarenal surgery) | Intervention Type: PROCEDURE; Name: ESWL; Assigned to Arm(s): ESWL (extracorporeal shockwaves lithotripsy) | Intervention Type: DEVICE; Name: Rigid and flexible ureteroscope; Assigned to Arm(s): RIRS (retrograde intrarenal surgery) | Intervention Type: DEVICE; Name: Lithotripter; Assigned to Arm(s): ESWL (extracorporeal shockwaves lithotripsy) | Intervention Type: DEVICE; Name: Holmium laser; Assigned to Arm(s): RIRS (retrograde intrarenal surgery) | Intervention Type: DEVICE; Name: Basket for fragment removal; Assigned to Arm(s): RIRS (retrograde intrarenal surgery) | Intervention Type: PROCEDURE; Name: General or spinal anesthesia; Assigned to Arm(s): RIRS (retrograde intrarenal surgery) | Intervention Type: DRUG; Name: Intravenous pain medication; Assigned to Arm(s): ESWL (extracorporeal shockwaves lithotripsy) | Intervention Type: DEVICE; Name: X-ray; Assigned to Arm(s): ESWL (extracorporeal shockwaves lithotripsy), RIRS (retrograde intrarenal surgery) | Intervention Type: DEVICE; Name: Ultrasound; Assigned to Arm(s): ESWL (extracorporeal shockwaves lithotripsy)
D: Arm Label: PCNL Group; Type: ACTIVE_COMPARATOR; Interventions: Procedure: PCNL | Arm Label: mini-PCNL Group; Type: ACTIVE_COMPARATOR; Interventions: Procedure: mini-PCNL | Arm Label: RIRS Group; Type: ACTIVE_COMPARATOR; Interventions: Procedure: RIRS | Intervention Type: PROCEDURE; Name: PCNL; Assigned to Arm(s): PCNL Group | Intervention Type: PROCEDURE; Name: mini-PCNL; Assigned to Arm(s): mini-PCNL Group | Intervention Type: PROCEDURE; Name: RIRS; Assigned to Arm(s): RIRS Group

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: Purpose: to investigate the postoperative outcomes of Retrograde intrarenal surgery versus percutaneous nephrolithotomy in 2 to 4 cm kidney stones.


Options:
A: Arm Label: RIRS; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Retrograde intrarenal surgery | Arm Label: PCNL; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Percutaneous nephrolithotomy | Intervention Type: PROCEDURE; Name: Percutaneous nephrolithotomy; Assigned to Arm(s): PCNL | Intervention Type: PROCEDURE; Name: Retrograde intrarenal surgery; Assigned to Arm(s): RIRS
B: Arm Label: Microperc surgery; Type: EXPERIMENTAL; Interventions: Procedure: Microperc surgery | Arm Label: FURS; Type: ACTIVE_COMPARATOR; Interventions: Procedure: FURS | Intervention Type: PROCEDURE; Name: Microperc surgery; Assigned to Arm(s): Microperc surgery | Intervention Type: PROCEDURE; Name: FURS; Assigned to Arm(s): FURS
C: Arm Label: Tamsulosin; Type: ACTIVE_COMPARATOR; Interventions: Drug: tamsulosin | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Intervention Type: DRUG; Name: tamsulosin; Assigned to Arm(s): Tamsulosin | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Placebo
D: Arm Label: 1 ESWL; Type: N/A; Interventions: N/A | Arm Label: 2 PCNL; Type: N/A; Interventions: N/A

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: Purpose: to investigate the postoperative outcomes of Retrograde intrarenal surgery versus percutaneous nephrolithotomy in 2 to 4 cm kidney stones.


Options:
A: Arm Label: RIRS; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Retrograde intrarenal surgery | Arm Label: PCNL; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Percutaneous nephrolithotomy | Intervention Type: PROCEDURE; Name: Percutaneous nephrolithotomy; Assigned to Arm(s): PCNL | Intervention Type: PROCEDURE; Name: Retrograde intrarenal surgery; Assigned to Arm(s): RIRS
B: Arm Label: tranexamic acid local; Type: ACTIVE_COMPARATOR; Interventions: Drug: Tranexamic acid injection | Arm Label: tranexamic acid IV; Type: ACTIVE_COMPARATOR; Interventions: Drug: Tranexamic acid injection | Intervention Type: DRUG; Name: Tranexamic acid injection; Assigned to Arm(s): tranexamic acid IV, tranexamic acid local
C: Arm Label: Microperc surgery; Type: EXPERIMENTAL; Interventions: Procedure: Microperc surgery | Arm Label: FURS; Type: ACTIVE_COMPARATOR; Interventions: Procedure: FURS | Intervention Type: PROCEDURE; Name: Microperc surgery; Assigned to Arm(s): Microperc surgery | Intervention Type: PROCEDURE; Name: FURS; Assigned to Arm(s): FURS
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: Tranexamic Acid | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Tranexamic Acid; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): 2

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effectiveness of Community-based Football Compared With Usual Care on Quality of Life in Men With Prostate Cancer: the FC Prostate Community Randomized Controlled Trial
Brief Summary: Prostate cancer is the most common malignancy in men. Three million are currently living in the United States with the disease and this number is expected to rise to four million in 2024. Most live many years with the disease and experience significant morbidity both due to disease progression and treatment toxicity. Exercise has shown to improve QoL and reduce treatment toxicity. Moreover epidemiological evidence has suggested that physical activity improves survival.

Football has been shown to induce positive effects on body composition and bone markers in a subgroup of prostate cancer patients, those receiving androgen deprivation therapy.

The objective is to examine the effectiveness of football in prostate cancer survivors.


Options:
A: Arm Label: Football; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Football | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Football; Assigned to Arm(s): Football
B: Arm Label: Arm I (strength training); Type: EXPERIMENTAL; Interventions: Behavioral: Exercise Intervention, Other: Questionnaire Administration | Arm Label: Arm II (tai chi); Type: EXPERIMENTAL; Interventions: Behavioral: Exercise Intervention, Other: Questionnaire Administration | Arm Label: Arm III (control); Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Exercise Intervention, Other: Questionnaire Administration | Intervention Type: BEHAVIORAL; Name: Exercise Intervention; Assigned to Arm(s): Arm I (strength training) | Intervention Type: BEHAVIORAL; Name: Exercise Intervention; Assigned to Arm(s): Arm II (tai chi) | Intervention Type: BEHAVIORAL; Name: Exercise Intervention; Assigned to Arm(s): Arm III (control) | Intervention Type: OTHER; Name: Questionnaire Administration; Assigned to Arm(s): Arm I (strength training), Arm II (tai chi), Arm III (control)
C: Intervention Type: BEHAVIORAL; Name: Strength training; Assigned to Arm(s): N/A
D: Arm Label: Exercising Together; Type: EXPERIMENTAL; Interventions: Behavioral: Randomized Exercise Intervention | Arm Label: Usual Care; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Randomized Exercise Intervention | Intervention Type: BEHAVIORAL; Name: Randomized Exercise Intervention; Assigned to Arm(s): Exercising Together | Intervention Type: BEHAVIORAL; Name: Randomized Exercise Intervention; Assigned to Arm(s): Usual Care

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Efficacy of Ketamine in Refractory Convulsive Status Epilepticus in Children: a Multicenter, Randomized, Controlled, Open-label, No-profit, With Sequential Design Study.
Brief Summary: To evaluate the efficacy of intravenous administration of ketamine in the treatment of refractory convulsive status epilepticus in children compared to administration of midazolam at high doses, thiopental and / or propofol.


Options:
A: Arm Label: 1 drug; Type: ACTIVE_COMPARATOR; Interventions: Drug: Diclofenac, Paracetamol, Ibuprofen | Arm Label: 2 drug; Type: PLACEBO_COMPARATOR; Interventions: Drug: Diclofenac, Paracetamol, Ibuprofen | Arm Label: 3 drug; Type: ACTIVE_COMPARATOR; Interventions: Drug: Diclofenac, Paracetamol, Ibuprofen | Arm Label: 4 drug; Type: ACTIVE_COMPARATOR; Interventions: Drug: Diclofenac, Paracetamol, Ibuprofen | Arm Label: 5 drug; Type: PLACEBO_COMPARATOR; Interventions: Drug: Diclofenac, Paracetamol, Ibuprofen | Intervention Type: DRUG; Name: Diclofenac, Paracetamol, Ibuprofen; Assigned to Arm(s): 1 drug, 2 drug, 3 drug, 4 drug, 5 drug
B: Arm Label: Intranasal Midazolam 0.2mg/kg; Type: ACTIVE_COMPARATOR; Interventions: Drug: Midazolam | Arm Label: Rectal Diazepam 0.3-0.5 mg/kg; Type: ACTIVE_COMPARATOR; Interventions: Drug: Diazepam | Intervention Type: DRUG; Name: Midazolam; Assigned to Arm(s): Intranasal Midazolam 0.2mg/kg | Intervention Type: DRUG; Name: Diazepam; Assigned to Arm(s): Rectal Diazepam 0.3-0.5 mg/kg
C: Arm Label: ketamine up to 100 mcg/kg/min; Type: EXPERIMENTAL; Interventions: Drug: Ketamine | Arm Label: midazolam & thiopental & propofol; Type: ACTIVE_COMPARATOR; Interventions: Drug: Ketamine | Intervention Type: DRUG; Name: Ketamine; Assigned to Arm(s): ketamine up to 100 mcg/kg/min, midazolam & thiopental & propofol
D: Intervention Type: DRUG; Name: intranasal lorazepam; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: intramuscular paraldehyde; Assigned to Arm(s): N/A

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen
Brief Summary: This study randomizes postmenopausal women with symptomatic pelvic organ prolapse planning native tissue transvaginal surgical repair to 6-8 weeks of preoperative and 1-year continued postoperative vaginal estrogen cream compared to placebo cream. This clinical trial and basic science investigation are designed to understand the mechanisms by which local estrogen treatment affects connective tissues of the pelvic floor and determine whether its use before and after prolapse repair will (i) improve success rates of the surgical intervention and minimize prolapse recurrence and (ii) impact favorably upon symptoms of other pelvic floor disorders.


Options:
A: Arm Label: PFMT plus routine pessary management; Type: ACTIVE_COMPARATOR; Interventions: Other: PFMT | Arm Label: Lifestyle; Type: ACTIVE_COMPARATOR; Interventions: Other: PFMT | Intervention Type: OTHER; Name: PFMT; Assigned to Arm(s): Lifestyle, PFMT plus routine pessary management
B: Arm Label: Premarin cream 0.5gm; Type: ACTIVE_COMPARATOR; Interventions: Drug: Vaginal conjugated estrogen cream 0.5gm | Arm Label: Premarin cream 1.0gm; Type: ACTIVE_COMPARATOR; Interventions: Drug: Vaginal conjugated estrogen cream 1.0gm | Arm Label: No intervention; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: Vaginal conjugated estrogen cream 0.5gm; Assigned to Arm(s): Premarin cream 0.5gm | Intervention Type: DRUG; Name: Vaginal conjugated estrogen cream 1.0gm; Assigned to Arm(s): Premarin cream 1.0gm
C: Arm Label: Estrogen Cream; Type: EXPERIMENTAL; Interventions: Drug: Conjugated Estrogens Cream | Arm Label: Placebo Cream; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo Cream | Intervention Type: DRUG; Name: Conjugated Estrogens Cream; Assigned to Arm(s): Estrogen Cream | Intervention Type: DRUG; Name: Placebo Cream; Assigned to Arm(s): Placebo Cream
D: Arm Label: Treatment group; Type: ACTIVE_COMPARATOR; Interventions: Drug: Premarin vaginal cream | Arm Label: Control group; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo cream | Intervention Type: DRUG; Name: Premarin vaginal cream; Assigned to Arm(s): Treatment group | Intervention Type: DRUG; Name: Placebo cream; Assigned to Arm(s): Control group

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: COBALT: Evaluation of CAR19 T-cells as an Optimal Bridge to Allogeneic Transplantation
Brief Summary: The purpose of this study is to administer novel cluster of differentiation antigen 19 (CD19) specific Chimeric Antigen Receptor T-cells (CAR19 T-cells) to patients with relapsed or resistant Diffuse Large B Cell Lymphoma (DLBCL) to assess the safety and efficacy of this strategy as a bridge to allogeneic transplantation.


Options:
A: Arm Label: anti-CD19 and anti-CD20 dual specific CAR-T Cells; Type: EXPERIMENTAL; Interventions: Biological: Autologous humanized anti-CD19 and anti-CD20 dual specific CAR-T Cells | Intervention Type: BIOLOGICAL; Name: Autologous humanized anti-CD19 and anti-CD20 dual specific CAR-T Cells; Assigned to Arm(s): anti-CD19 and anti-CD20 dual specific CAR-T Cells
B: Arm Label: Tisagenlecleucel; Type: EXPERIMENTAL; Interventions: Biological: Tisagenlecleucel, Drug: Lymphodepleting chemotherapy | Intervention Type: BIOLOGICAL; Name: Tisagenlecleucel; Assigned to Arm(s): Tisagenlecleucel | Intervention Type: DRUG; Name: Lymphodepleting chemotherapy; Assigned to Arm(s): Tisagenlecleucel
C: Arm Label: Dose Escalation; Type: EXPERIMENTAL; Interventions: Combination Product: CLBR001 and SWI019 | Intervention Type: COMBINATION_PRODUCT; Name: CLBR001 and SWI019; Assigned to Arm(s): Dose Escalation
D: Arm Label: CAR19 T-cells; Type: EXPERIMENTAL; Interventions: Procedure: Leukapheresis, Drug: Cyclophosphamide, Drug: Fludarabine, Biological: CAR19 T-Cells | Intervention Type: PROCEDURE; Name: Leukapheresis; Assigned to Arm(s): CAR19 T-cells | Intervention Type: DRUG; Name: Cyclophosphamide; Assigned to Arm(s): CAR19 T-cells | Intervention Type: DRUG; Name: Fludarabine; Assigned to Arm(s): CAR19 T-cells | Intervention Type: BIOLOGICAL; Name: CAR19 T-Cells; Assigned to Arm(s): CAR19 T-cells

Answer: D