Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Multicenter, Randomized, Double-Blind Active-Controlled, Phase 3 Trial to Evaluate the Efficacy and Safety of Saxagliptin in Combination With Metformin IR as Initial Therapy Compared to Saxagliptin Monotherapy and to Metformin IR Monotherapy in Subjects With Type 2 Diabetes Who Have Inadequate Glycemic Control
Brief Summary: The purpose of this trial is to understand if adding saxagliptin to metformin therapy is safe and works better than taking either saxagliptin or metformin alone


Options:
A: Arm Label: metformin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Metformin | Arm Label: gastric banding; Type: EXPERIMENTAL; Interventions: Device: gastric banding | Intervention Type: DRUG; Name: Metformin; Assigned to Arm(s): metformin | Intervention Type: DEVICE; Name: gastric banding; Assigned to Arm(s): gastric banding
B: Arm Label: LY2189265 1.5 mg; Type: EXPERIMENTAL; Interventions: Drug: LY2189265, Drug: Metformin, Drug: Glimepiride | Arm Label: LY2189265 0.75 mg; Type: EXPERIMENTAL; Interventions: Drug: LY2189265, Drug: Metformin, Drug: Glimepiride | Arm Label: Insulin Glargine; Type: ACTIVE_COMPARATOR; Interventions: Drug: Insulin Glargine, Drug: Metformin, Drug: Glimepiride | Intervention Type: DRUG; Name: Insulin Glargine; Assigned to Arm(s): Insulin Glargine | Intervention Type: DRUG; Name: LY2189265; Assigned to Arm(s): LY2189265 0.75 mg, LY2189265 1.5 mg | Intervention Type: DRUG; Name: Metformin; Assigned to Arm(s): Insulin Glargine, LY2189265 0.75 mg, LY2189265 1.5 mg | Intervention Type: DRUG; Name: Glimepiride; Assigned to Arm(s): Insulin Glargine, LY2189265 0.75 mg, LY2189265 1.5 mg
C: Arm Label: Saxagliptin and Metformin (A); Type: EXPERIMENTAL; Interventions: Drug: Saxagliptin, Drug: Metformin, Drug: pioglitazone | Arm Label: Saxagliptin and Metformin (B); Type: EXPERIMENTAL; Interventions: Drug: Saxagliptin, Drug: Metformin, Drug: pioglitazone | Arm Label: Saxagliptin and Placebo (C); Type: EXPERIMENTAL; Interventions: Drug: Saxagliptin, Drug: Placebo, Drug: pioglitazone | Arm Label: Metformin and Placebo (D); Type: ACTIVE_COMPARATOR; Interventions: Drug: Metformin, Drug: Placebo, Drug: pioglitazone | Intervention Type: DRUG; Name: Saxagliptin; Assigned to Arm(s): Saxagliptin and Metformin (A), Saxagliptin and Placebo (C) | Intervention Type: DRUG; Name: Saxagliptin; Assigned to Arm(s): Saxagliptin and Metformin (B) | Intervention Type: DRUG; Name: Metformin; Assigned to Arm(s): Metformin and Placebo (D), Saxagliptin and Metformin (A), Saxagliptin and Metformin (B) | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Metformin and Placebo (D), Saxagliptin and Placebo (C) | Intervention Type: DRUG; Name: pioglitazone; Assigned to Arm(s): Metformin and Placebo (D), Saxagliptin and Metformin (A), Saxagliptin and Metformin (B), Saxagliptin and Placebo (C)
D: Arm Label: Metformin,lifestyle counselling; Type: ACTIVE_COMPARATOR; Interventions: Drug: rosiglitazone, Drug: metformin, Drug: Anti-diabetic medications | Intervention Type: DRUG; Name: rosiglitazone; Assigned to Arm(s): Metformin,lifestyle counselling | Intervention Type: DRUG; Name: metformin; Assigned to Arm(s): Metformin,lifestyle counselling | Intervention Type: DRUG; Name: Anti-diabetic medications; Assigned to Arm(s): Metformin,lifestyle counselling

Answer: C