Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Adverse Metabolic Effects of Dietary Sugar: Ad Libitum vs Energy-balanced Diets
Brief Summary: It is not known whether consumption of excessive amounts of sugar can increase risk factors for cardiovascular disease or diabetes in the absence of increased food (caloric) intake and weight gain, nor whether the negative effects of sugar consumption are made worse when accompanied by weight gain. This study will investigate the effects of excess sugar when consumed with an energy-balanced diet that prevents weight gain, and the effects of excess sugar when consumed with a diet that can cause weight gain. The results will determine whether excess sugar consumption and excess caloric intake that lead to weight gain have independent and additive effects on risk factors for cardiovascular disease or diabetes, and will have the potential to influence dietary guidelines and public health policy.


Options:
A: Arm Label: Enhanced Portfolio plus structured exercise; Type: EXPERIMENTAL; Interventions: Behavioral: Enhanced portfolio plus structured exercise | Arm Label: High fiber diet plus routine exercise; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: High fiber diet plus routine exercise | Intervention Type: BEHAVIORAL; Name: Enhanced portfolio plus structured exercise; Assigned to Arm(s): Enhanced Portfolio plus structured exercise | Intervention Type: BEHAVIORAL; Name: High fiber diet plus routine exercise; Assigned to Arm(s): High fiber diet plus routine exercise
B: Arm Label: Low-fat dairy; Type: EXPERIMENTAL; Interventions: Other: Low-fat dairy | Arm Label: Sugar-sweetened beverages; Type: PLACEBO_COMPARATOR; Interventions: Other: Sugar-sweetened beverages | Intervention Type: OTHER; Name: Low-fat dairy; Assigned to Arm(s): Low-fat dairy | Intervention Type: OTHER; Name: Sugar-sweetened beverages; Assigned to Arm(s): Sugar-sweetened beverages
C: Arm Label: HFCS-EB; Type: EXPERIMENTAL; Interventions: Other: high fructose corn syrup, Other: Energy-balanced diet | Arm Label: Asp-EB; Type: PLACEBO_COMPARATOR; Interventions: Other: aspartame, Other: Energy-balanced diet | Arm Label: HFCS-AL; Type: EXPERIMENTAL; Interventions: Other: high fructose corn syrup, Other: Ad libitum diet | Arm Label: Asp-AL; Type: PLACEBO_COMPARATOR; Interventions: Other: aspartame, Other: Ad libitum diet | Intervention Type: OTHER; Name: high fructose corn syrup; Assigned to Arm(s): HFCS-AL, HFCS-EB | Intervention Type: OTHER; Name: aspartame; Assigned to Arm(s): Asp-AL, Asp-EB | Intervention Type: OTHER; Name: Energy-balanced diet; Assigned to Arm(s): Asp-EB, HFCS-EB | Intervention Type: OTHER; Name: Ad libitum diet; Assigned to Arm(s): Asp-AL, HFCS-AL
D: Arm Label: Sugar-sweetened beverage (SSB); Type: ACTIVE_COMPARATOR; Interventions: Other: Sugar-sweetened beverage (SSB) | Arm Label: Non-nutritive sweetened beverage (NSB); Type: EXPERIMENTAL; Interventions: Other: Non-nutritive sweetened beverages (NSB) | Arm Label: Water; Type: EXPERIMENTAL; Interventions: Other: Water | Intervention Type: OTHER; Name: Sugar-sweetened beverage (SSB); Assigned to Arm(s): Sugar-sweetened beverage (SSB) | Intervention Type: OTHER; Name: Non-nutritive sweetened beverages (NSB); Assigned to Arm(s): Non-nutritive sweetened beverage (NSB) | Intervention Type: OTHER; Name: Water; Assigned to Arm(s): Water

Answer: C