Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Physical Training and Cancer- Effects and Understanding of Mechanisms for Prevent and Minimizing Cancer Related Fatigue, Improve Quality of Life and Disease Outcome
Brief Summary: Excessive tiredness (fatigue) is a common problem in cancer patients and can affect quality of life negatively. There is limited knowledge about the physical mechanisms that cause fatigue, and there is no medical treatment. Physical activity can reduce the inconvenience, but the investigators need to learn more about the type and intensity of exercise that works the best as well as how to motivate patients to exercise. The overall aim, is to evaluate the efficacy and cost-effectiveness of individually tailored high (H) and low/medium (LM) intensity physical training, with or without behavioural medicine (BM) support strategies, during adjuvant oncological treatment on; Cancer Related Fatigue (CRF),Quality of Life (QoL), mood disturbance, adherence to the cancer treatment, adverse effects, disease outcome, return to a daily life after completed treatment and return to work. The investigators will also describe changes in inflammatory markers and cytokines related to physical training and gene expressions following training to investigate whether these serve as mediators for the effects of physical training on CRF and QoL. This will be evaluated in newly diagnosed breast, colorectal and prostate cancer patients during adjuvant therapy at three different centres in Sweden; Uppsala, Lund/Malmö and Linköping. A 2x2 factorial design will be used, 600 patients will be randomised to H, H+BM, LM or LM+BM. Patients will train two times per week during 6 months. This project will give; new knowledge about aspects for individuals to gain improved well-being and quality of life, facilitated return to work, and possibly reduced risk of cancer recurrence. This in turn would result in lower burden on the health care system, reduced societal costs and have a positive impact on public health. Implementation of the results into clinical practice will be facilitated by the close collaboration between researchers and clinicians, and the fact that the study is performed in clinical settings.


Options:
A: Arm Label: Hatha yoga; Type: EXPERIMENTAL; Interventions: Behavioral: Hatha yoga | Arm Label: Usual care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Hatha yoga; Assigned to Arm(s): Hatha yoga
B: Arm Label: Rectal Cancer; Type: N/A; Interventions: N/A
C: Arm Label: High intensity; Type: EXPERIMENTAL; Interventions: Behavioral: high intensity exercise | Arm Label: Low/Medium intensity; Type: EXPERIMENTAL; Interventions: Behavioral: low/medium intensity exercise | Arm Label: High Intensity with BM; Type: EXPERIMENTAL; Interventions: Behavioral: high intensity exercise, Behavioral: Behavioral medicine strategies | Arm Label: Low/Medium intensity with BM; Type: EXPERIMENTAL; Interventions: Behavioral: low/medium intensity exercise, Behavioral: Behavioral medicine strategies | Intervention Type: BEHAVIORAL; Name: high intensity exercise; Assigned to Arm(s): High Intensity with BM, High intensity | Intervention Type: BEHAVIORAL; Name: low/medium intensity exercise; Assigned to Arm(s): Low/Medium intensity, Low/Medium intensity with BM | Intervention Type: BEHAVIORAL; Name: Behavioral medicine strategies; Assigned to Arm(s): High Intensity with BM, Low/Medium intensity with BM
D: Arm Label: Exercise; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise | Arm Label: Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Exercise; Assigned to Arm(s): Exercise

Answer: C