Please select the eligibility criteria that correspond to the clinical trial below.
Title: ACtive Care After Transplantation, a Lifestyle Intervention in Renal Transplant Recipients
Brief Summary: The aim of the present study is to compare the outcomes of standard care to the effects of exercise alone, and exercise combined with nutrition counseling, on post-transplantation weight gain and quality of life in renal transplant recipients (RTR). The primary outcome is subdomain physical functioning of quality of life, (SF-36 PFS).

Secondary outcomes include other evaluations of quality of life (SF-36, KDQOL-SF, EQ-5D), objective measures of physical functioning (aerobic capacity and muscle strength), level of physical activity, gain in adiposity (body fat percentage by bio-electrical impedance assessment, BMI, waist circumference), and cardiometabolic risk factors (blood pressure, lipids, glucose metabolism). Additionally it is planned to study data on renal function, medical history, medication, psychological factors (motivation, kinesiophobia, coping style), nutrition knowledge, nutrition intake, nutrition status, fatigue, work participation, process evaluation and cost-effectiveness.


Options:
A: Inclusion Criteria:

* Diabetes mellitus
* CKD Stages 2-4
* BMI \> 30
* Persistent proteinuria (urine protein/creatinine \> 200 mg/g for \> 3 mo)
* On treatment with ACE inhibitor or ARB
* On treatment with aspirin
* On treatment with statin (if LDL \> 100)

Exclusion Criteria:

* Symptomatic neuropathy/retinopathy
* Positive stress test due to coronary arterial disease
* Symptomatic cardiovascular disease
* Congestive heart failure (New York Heart Association Class III or IV)
* Chronic obstructive pulmonary disease (FEV1 \< 50% predicted and/or requires supplemental oxygen support during exercise)
* Complaints of angina during the stress test
* Cerebrovascular disease/cognitive impairment
* Renal transplant
* Inability to walk on the treadmill
* Any unforeseen illness or disability that would preclude exercise testing or training
* Participation in a formal exercise program within the previous 12 weeks
B: Inclusion Criteria:

* Age ≥ 18 years;
* Informed Consent;
* \>1 year after transplantation
* Medical approvement for participation in the study by the nephrologist.

Exclusion Criteria:

* Psychopathology;
* Severe cognitive disorders;
* Negative advice of the nephrologist and/or cardiologist.
C: Inclusion Criteria:

* Biopsy-proven IgA nephropathy
* body mass index more than 23 Kg/m2
* 24 hours urine protein more than 1 g
* estimated GFR more than 20 ml/min

Exclusion Criteria:

* pregnancy and lactation
* rapidly renal function decline
* crescent formation in renal biopsy more than 10%
D: Inclusion Criteria:

* BMI\>27
* age\>40
* History of CHD or diabetes in any age or BMI level

Exclusion Criteria:

* Pregnant or lactating women.
* Active drug or alcohol use or dependence that, in the opinion of the site investigator, would interfere with adherence to study requirements.
* Serum creatinine \> 3 mg/dl.
* Liver dysfunction ( ³ 2 fold level of ALT and AST enzymes).
* Participation in another trial in which active intervention is being received.
* Any intestinal problem that would prevent the patient from eating one of the test diets (for example, gastric stapling that might prevent consumption of vegetables).

Answer: B