Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized, Double-Blind, Placebo-Controlled Trial to Compare the Duration of Analgesic Efficacy and Safety of Naproxen Sodium Tablets and Ibuprofen Tablets in Postsurgical Dental Pain
Brief Summary: To compare the duration of analgesic efficacy as determined by the time to rescue medication of a single oral dose of naproxen sodium 440 mg (2 x 220 mg tablets) relative to ibuprofen 400 mg (2 x 200 mg tablets) and placebo over 24 hours in subjects experiencing moderate to severe post-impaction surgery dental pain.

To compare the overall analgesic effect (SPID 0-24) of a single dose of naproxen sodium 440 mg (2 x 220 mg tablets) relative to ibuprofen 400 mg (2 x 200 mg tablets) and placebo.

To compare the overall relief from pain (TOTPAR 0-24) of a single dose of naproxen sodium 440 mg (2 x 220 mg tablets) relative to ibuprofen 400 mg (2 x 200 mg tablets) and placebo.


Options:
A: Arm Label: Treatment with Ibuprofen; Type: EXPERIMENTAL; Interventions: Drug: Ibuprofen | Arm Label: Treatment with Acetaminophen; Type: ACTIVE_COMPARATOR; Interventions: Drug: Acetaminophen | Intervention Type: DRUG; Name: Ibuprofen; Assigned to Arm(s): Treatment with Ibuprofen | Intervention Type: DRUG; Name: Acetaminophen; Assigned to Arm(s): Treatment with Acetaminophen
B: Arm Label: intravenous ibuprofen; Type: ACTIVE_COMPARATOR; Interventions: Drug: Intravenous ibuprofen | Arm Label: normal saline; Type: PLACEBO_COMPARATOR; Interventions: Other: Normal saline as placebo comparator | Intervention Type: OTHER; Name: Normal saline as placebo comparator; Assigned to Arm(s): normal saline | Intervention Type: DRUG; Name: Intravenous ibuprofen; Assigned to Arm(s): intravenous ibuprofen
C: Arm Label: Naproxen Sodium (Aleve, BAY117031); Type: EXPERIMENTAL; Interventions: Drug: Naproxen Sodium (Aleve, BAY117031) | Arm Label: Ibuprofen (Advil); Type: ACTIVE_COMPARATOR; Interventions: Drug: Ibuprofen (Advil) | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Naproxen Sodium (Aleve, BAY117031); Assigned to Arm(s): Naproxen Sodium (Aleve, BAY117031) | Intervention Type: DRUG; Name: Ibuprofen (Advil); Assigned to Arm(s): Ibuprofen (Advil) | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
D: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: Ibuprofen; Type: ACTIVE_COMPARATOR; Interventions: Drug: Ibuprofen | Arm Label: TRAM.HCl high dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: Tramadol Hydrochloride | Arm Label: TRAM.HCl low dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: Tramadol Hydrochloride | Arm Label: DKP-TRIS high dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: Dexketoprofen Trometamol | Arm Label: DKP-TRIS low dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: Dexketoprofen Trometamol | Arm Label: DKP-TRIS low dose - TRAM.HCl low dose; Type: EXPERIMENTAL; Interventions: Drug: Dexketoprofen Trometamol + Tramadol Hydrochloride | Arm Label: DKP-TRIS low dose - TRAM.HCl high dose; Type: EXPERIMENTAL; Interventions: Drug: Dexketoprofen Trometamol + Tramadol Hydrochloride | Arm Label: DKP-TRIS high dose - TRAM.HCl low dose; Type: EXPERIMENTAL; Interventions: Drug: Dexketoprofen Trometamol + Tramadol Hydrochloride | Arm Label: DKP-TRIS high dose - TRAM.HCl high dose; Type: EXPERIMENTAL; Interventions: Drug: Dexketoprofen Trometamol + Tramadol Hydrochloride | Intervention Type: DRUG; Name: Dexketoprofen Trometamol; Assigned to Arm(s): DKP-TRIS low dose | Intervention Type: DRUG; Name: Dexketoprofen Trometamol; Assigned to Arm(s): DKP-TRIS high dose | Intervention Type: DRUG; Name: Tramadol Hydrochloride; Assigned to Arm(s): TRAM.HCl low dose | Intervention Type: DRUG; Name: Tramadol Hydrochloride; Assigned to Arm(s): TRAM.HCl high dose | Intervention Type: DRUG; Name: Ibuprofen; Assigned to Arm(s): Ibuprofen | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo | Intervention Type: DRUG; Name: Dexketoprofen Trometamol + Tramadol Hydrochloride; Assigned to Arm(s): DKP-TRIS low dose - TRAM.HCl low dose | Intervention Type: DRUG; Name: Dexketoprofen Trometamol + Tramadol Hydrochloride; Assigned to Arm(s): DKP-TRIS low dose - TRAM.HCl high dose | Intervention Type: DRUG; Name: Dexketoprofen Trometamol + Tramadol Hydrochloride; Assigned to Arm(s): DKP-TRIS high dose - TRAM.HCl low dose | Intervention Type: DRUG; Name: Dexketoprofen Trometamol + Tramadol Hydrochloride; Assigned to Arm(s): DKP-TRIS high dose - TRAM.HCl high dose

Answer: C