TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Prospective, Randomized, Double-Blind, Controlled Study on the Clinical Effects of Hyperbaric Therapy in Autistic Children
Brief Summary: Autism is a neurodevelopmental disorder currently affecting as many as 1 out of 166 children in the United States. Autism is considered by many to be a permanent condition with little hope for improvement. Treatment for autism is centered on special schooling and behavioral therapy; medical science currently has little to offer. Recent research has discovered that some autistic individuals have decreased blood flow to the brain, evidence of gastrointestinal and brain inflammation, increased markers of oxidative stress, and a relative mitochondrial dysfunction. Hyperbaric oxygen therapy (HBOT) can compensate for decreased blood flow by increasing the oxygen content of plasma and body tissues and can even normalize oxygen levels in ischemic tissue. In addition, animal studies have shown that HBOT has potent anti-inflammatory effects and reduces oxidative stress. Furthermore, recent evidence demonstrates that HBOT increases the production of mitochondria and mobilizes stem cells from human bone marrow, which may aid recovery in neurodegenerative diseases. Based upon these findings, it is hypothesized that HBOT will improve symptoms in autistic individuals.

Our recent retrospective case series demonstrated that HBOT may improve symptoms in autistic children. We recently completed a prospective pilot trial using HBOT in 18 children which demonstrated significant clinical improvements in autistic children on several standardized scales. Most of the scales were parent-rated, although some were rated by teachers. However, parents were not blinded to the fact that their children received HBOT and evaluation of the children was through parent-rated scales, either of which could lead to bias. There was no placebo or control group. Therefore, the improvements found in this prospective study could have been due merely to chance or the natural development of the children. To determine if HBOT improves symptoms in autistic children, a double-blind controlled study is needed.


Options:
A: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Other: Hyperbaric Oxygen Treatment (HBOT) | Intervention Type: OTHER; Name: Hyperbaric Oxygen Treatment (HBOT); Assigned to Arm(s): 1
B: Intervention Type: DEVICE; Name: Hyperbaric Oxygen Therapy; Assigned to Arm(s): N/A
C: Arm Label: Treatment- HBOT; Type: EXPERIMENTAL; Interventions: Procedure: Hyperbaric Oxygen Therapy (HBOT) | Arm Label: control-HBOT; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: PROCEDURE; Name: Hyperbaric Oxygen Therapy (HBOT); Assigned to Arm(s): Treatment- HBOT
D: Intervention Type: PROCEDURE; Name: Hyperbaric Therapy; Assigned to Arm(s): N/A

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Gabapentin Extended Release (G-ER) Tablets in the Treatment of Patients With Postherpetic Neuralgia
Brief Summary: Gabapentin and pregabalin are treatments for some types of neuropathic pain, including postherpetic neuralgia (PHN). However, these treatments usually need to be taken 3 times a day for effective pain control. The purpose of this study is to determine whether a new gabapentin tablet, which only needs to be taken once or twice a day, is safe and effective for the treatment of postherpetic neuralgia.


Options:
A: Arm Label: gabapentin; Type: EXPERIMENTAL; Interventions: Drug: gabapentin | Arm Label: placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: placebo | Intervention Type: DRUG; Name: gabapentin; Assigned to Arm(s): gabapentin | Intervention Type: OTHER; Name: placebo; Assigned to Arm(s): placebo
B: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: GEn 1200mg/day; Type: EXPERIMENTAL; Interventions: Drug: GEn 1200mg/day | Arm Label: GEn 2400mg/day; Type: EXPERIMENTAL; Interventions: Drug: GEn 2400mg/day | Arm Label: GEn 3600mg/day; Type: EXPERIMENTAL; Interventions: Drug: GEn 3600mg/day | Intervention Type: DRUG; Name: GEn 1200mg/day; Assigned to Arm(s): GEn 1200mg/day | Intervention Type: DRUG; Name: GEn 2400mg/day; Assigned to Arm(s): GEn 2400mg/day | Intervention Type: DRUG; Name: GEn 3600mg/day; Assigned to Arm(s): GEn 3600mg/day | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
C: Intervention Type: DRUG; Name: Gabapentin extended-release tablets; Assigned to Arm(s): N/A
D: Arm Label: GEn 1200mg/day; Type: EXPERIMENTAL; Interventions: Drug: GEn 1200mg/day | Arm Label: GEn 3600mg/day; Type: EXPERIMENTAL; Interventions: Drug: GEn 3600mg/day | Intervention Type: DRUG; Name: GEn 1200mg/day; Assigned to Arm(s): GEn 1200mg/day | Intervention Type: DRUG; Name: GEn 3600mg/day; Assigned to Arm(s): GEn 3600mg/day

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Gabapentin Extended Release (G-ER) Tablets in the Treatment of Patients With Postherpetic Neuralgia
Brief Summary: Gabapentin and pregabalin are treatments for some types of neuropathic pain, including postherpetic neuralgia (PHN). However, these treatments usually need to be taken 3 times a day for effective pain control. The purpose of this study is to determine whether a new gabapentin tablet, which only needs to be taken once or twice a day, is safe and effective for the treatment of postherpetic neuralgia.


Options:
A: Intervention Type: DRUG; Name: Gabapentin extended-release tablets; Assigned to Arm(s): N/A
B: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: Gabapentin Extended Release tablets | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Gabapentin Extended Release tablets; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): 2
C: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: Pregabalin; Type: OTHER; Interventions: Drug: Pregabalin | Arm Label: GEn 1200mg/day; Type: EXPERIMENTAL; Interventions: Drug: GEn 1200mg/day | Arm Label: GEn 2400mg/day; Type: EXPERIMENTAL; Interventions: Drug: GEn 2400mg/day | Arm Label: GEn 3600mg/day; Type: EXPERIMENTAL; Interventions: Drug: GEn 3600mg/day | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo | Intervention Type: DRUG; Name: GEn 1200mg/day; Assigned to Arm(s): GEn 1200mg/day | Intervention Type: DRUG; Name: GEn 2400mg/day; Assigned to Arm(s): GEn 2400mg/day | Intervention Type: DRUG; Name: GEn 3600mg/day; Assigned to Arm(s): GEn 3600mg/day | Intervention Type: DRUG; Name: Pregabalin; Assigned to Arm(s): Pregabalin
D: Arm Label: Pregabalin; Type: ACTIVE_COMPARATOR; Interventions: Drug: pregabalin | Arm Label: Duloxetine; Type: EXPERIMENTAL; Interventions: Drug: duloxetine hydrochloride | Arm Label: Gabapentin + Duloxetine; Type: EXPERIMENTAL; Interventions: Drug: duloxetine hydrochloride, Drug: gabapentin | Intervention Type: DRUG; Name: duloxetine hydrochloride; Assigned to Arm(s): Duloxetine, Gabapentin + Duloxetine | Intervention Type: DRUG; Name: pregabalin; Assigned to Arm(s): Pregabalin | Intervention Type: DRUG; Name: gabapentin; Assigned to Arm(s): Gabapentin + Duloxetine

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: Behavioral intervention at Kindergarten setting aiming at increased fruit and vegetable consumption, decreased intake of high energy foods, snacks, sweets, increased intake of water/low energy drinks, decreased intake of high energy drinks. Physical activity should be more than 1 hour/day and TV/media consumption less than 1 hour/day.

Main questions are:

Do children differ in intervention and control kindergartens according to their nutrition behaviour? Do children in the intervention kindergartens have a higher physical training than such in the control kindergartens? Data were collected with a standardised questionnaire.

Do children differ in intervention and control kindergartens according to their body mass index?


Options:
A: Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Intervention group; Type: EXPERIMENTAL; Interventions: Behavioral: Lifestyle intervention | Intervention Type: BEHAVIORAL; Name: Lifestyle intervention; Assigned to Arm(s): Intervention group
B: Arm Label: Train-the-Trainers Arm; Type: EXPERIMENTAL; Interventions: Behavioral: Healthy Caregivers- Healthy Children Toolkit | Arm Label: Attention Control Arm; Type: OTHER; Interventions: Behavioral: Safety Curriculum | Intervention Type: BEHAVIORAL; Name: Healthy Caregivers- Healthy Children Toolkit; Assigned to Arm(s): Train-the-Trainers Arm | Intervention Type: BEHAVIORAL; Name: Safety Curriculum; Assigned to Arm(s): Attention Control Arm
C: Arm Label: Treatment; Type: EXPERIMENTAL; Interventions: Other: Childhood Obesity | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Childhood Obesity; Assigned to Arm(s): Treatment
D: Intervention Type: BEHAVIORAL; Name: attitude change; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: adiposity prevention program; Assigned to Arm(s): N/A

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: Behavioral intervention at Kindergarten setting aiming at increased fruit and vegetable consumption, decreased intake of high energy foods, snacks, sweets, increased intake of water/low energy drinks, decreased intake of high energy drinks. Physical activity should be more than 1 hour/day and TV/media consumption less than 1 hour/day.

Main questions are:

Do children differ in intervention and control kindergartens according to their nutrition behaviour? Do children in the intervention kindergartens have a higher physical training than such in the control kindergartens? Data were collected with a standardised questionnaire.

Do children differ in intervention and control kindergartens according to their body mass index?


Options:
A: Arm Label: Immediate Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Healthy Eating and Physical Activity | Arm Label: Delayed Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Healthy Eating and Physical Activity | Intervention Type: BEHAVIORAL; Name: Healthy Eating and Physical Activity; Assigned to Arm(s): Delayed Intervention, Immediate Intervention
B: Intervention Type: BEHAVIORAL; Name: attitude change; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: adiposity prevention program; Assigned to Arm(s): N/A
C: Arm Label: parent-targeted intervention; Type: EXPERIMENTAL; Interventions: Behavioral: multi-component/setting parent-targeted intervention | Arm Label: Primary Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: multi-component/setting parent-targeted intervention; Assigned to Arm(s): parent-targeted intervention
D: Arm Label: Standard HVP Curriculum; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Standard HVP Curriculum | Arm Label: Obesity Prevention; Type: EXPERIMENTAL; Interventions: Behavioral: Standard HVP Curriculum, Behavioral: Obesity Prevention | Intervention Type: BEHAVIORAL; Name: Standard HVP Curriculum; Assigned to Arm(s): Obesity Prevention, Standard HVP Curriculum | Intervention Type: BEHAVIORAL; Name: Obesity Prevention; Assigned to Arm(s): Obesity Prevention

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: Behavioral intervention at Kindergarten setting aiming at increased fruit and vegetable consumption, decreased intake of high energy foods, snacks, sweets, increased intake of water/low energy drinks, decreased intake of high energy drinks. Physical activity should be more than 1 hour/day and TV/media consumption less than 1 hour/day.

Main questions are:

Do children differ in intervention and control kindergartens according to their nutrition behaviour? Do children in the intervention kindergartens have a higher physical training than such in the control kindergartens? Data were collected with a standardised questionnaire.

Do children differ in intervention and control kindergartens according to their body mass index?


Options:
A: Arm Label: Intervention arm; Type: EXPERIMENTAL; Interventions: Behavioral: Healthy Start | Arm Label: Control arm; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Healthy Start; Assigned to Arm(s): Intervention arm
B: Arm Label: Treatment; Type: EXPERIMENTAL; Interventions: Other: Childhood Obesity | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Childhood Obesity; Assigned to Arm(s): Treatment
C: Intervention Type: BEHAVIORAL; Name: attitude change; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: adiposity prevention program; Assigned to Arm(s): N/A
D: Arm Label: motivational counseling; Type: EXPERIMENTAL; Interventions: Behavioral: motivational counseling | Arm Label: Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: motivational counseling; Assigned to Arm(s): motivational counseling

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: Behavioral intervention at Kindergarten setting aiming at increased fruit and vegetable consumption, decreased intake of high energy foods, snacks, sweets, increased intake of water/low energy drinks, decreased intake of high energy drinks. Physical activity should be more than 1 hour/day and TV/media consumption less than 1 hour/day.

Main questions are:

Do children differ in intervention and control kindergartens according to their nutrition behaviour? Do children in the intervention kindergartens have a higher physical training than such in the control kindergartens? Data were collected with a standardised questionnaire.

Do children differ in intervention and control kindergartens according to their body mass index?


Options:
A: Arm Label: Basic WISE strategy; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: WISE (We Inspire Smart Eating) | Arm Label: Enhanced WISE strategy; Type: EXPERIMENTAL; Interventions: Behavioral: WISE (We Inspire Smart Eating) | Intervention Type: BEHAVIORAL; Name: WISE (We Inspire Smart Eating); Assigned to Arm(s): Basic WISE strategy, Enhanced WISE strategy
B: Arm Label: Train-the-Trainers Arm; Type: EXPERIMENTAL; Interventions: Behavioral: Healthy Caregivers- Healthy Children Toolkit | Arm Label: Attention Control Arm; Type: OTHER; Interventions: Behavioral: Safety Curriculum | Intervention Type: BEHAVIORAL; Name: Healthy Caregivers- Healthy Children Toolkit; Assigned to Arm(s): Train-the-Trainers Arm | Intervention Type: BEHAVIORAL; Name: Safety Curriculum; Assigned to Arm(s): Attention Control Arm
C: Arm Label: Usual Head Start Exposure; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Parents of Preschoolers Series (POPS); Type: EXPERIMENTAL; Interventions: Behavioral: Parents of Preschoolers Series | Arm Label: POPS + Incredible Years Series (IYS); Type: EXPERIMENTAL; Interventions: Behavioral: Parents of Preschoolers Series, Behavioral: Incredible Years Series | Intervention Type: BEHAVIORAL; Name: Parents of Preschoolers Series; Assigned to Arm(s): POPS + Incredible Years Series (IYS), Parents of Preschoolers Series (POPS) | Intervention Type: BEHAVIORAL; Name: Incredible Years Series; Assigned to Arm(s): POPS + Incredible Years Series (IYS)
D: Intervention Type: BEHAVIORAL; Name: attitude change; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: adiposity prevention program; Assigned to Arm(s): N/A

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: Behavioral intervention at Kindergarten setting aiming at increased fruit and vegetable consumption, decreased intake of high energy foods, snacks, sweets, increased intake of water/low energy drinks, decreased intake of high energy drinks. Physical activity should be more than 1 hour/day and TV/media consumption less than 1 hour/day.

Main questions are:

Do children differ in intervention and control kindergartens according to their nutrition behaviour? Do children in the intervention kindergartens have a higher physical training than such in the control kindergartens? Data were collected with a standardised questionnaire.

Do children differ in intervention and control kindergartens according to their body mass index?


Options:
A: Arm Label: Individualized dietetic intervention; Type: OTHER; Interventions: Behavioral: Individualized dietetic intervention-eating habits | Intervention Type: BEHAVIORAL; Name: Individualized dietetic intervention-eating habits; Assigned to Arm(s): Individualized dietetic intervention
B: Arm Label: intervention 1; Type: EXPERIMENTAL; Interventions: Behavioral: classroom curriculum, Behavioral: In-service training for Head Start teachers/aides, Behavioral: Training for Head Start food service, Behavioral: Family intervention component, Behavioral: Food source, Behavioral: Health care providers, Behavioral: CHILE Head Start Intervention | Arm Label: control 2; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: classroom curriculum; Assigned to Arm(s): intervention 1 | Intervention Type: BEHAVIORAL; Name: In-service training for Head Start teachers/aides; Assigned to Arm(s): intervention 1 | Intervention Type: BEHAVIORAL; Name: Training for Head Start food service; Assigned to Arm(s): intervention 1 | Intervention Type: BEHAVIORAL; Name: Family intervention component; Assigned to Arm(s): intervention 1 | Intervention Type: BEHAVIORAL; Name: Food source; Assigned to Arm(s): intervention 1 | Intervention Type: BEHAVIORAL; Name: Health care providers; Assigned to Arm(s): intervention 1 | Intervention Type: BEHAVIORAL; Name: CHILE Head Start Intervention; Assigned to Arm(s): intervention 1
C: Arm Label: Lifestyle counseling; Type: EXPERIMENTAL; Interventions: Behavioral: Lifestyle counseling | Intervention Type: BEHAVIORAL; Name: Lifestyle counseling; Assigned to Arm(s): Lifestyle counseling
D: Intervention Type: BEHAVIORAL; Name: attitude change; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: adiposity prevention program; Assigned to Arm(s): N/A

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: Behavioral intervention at Kindergarten setting aiming at increased fruit and vegetable consumption, decreased intake of high energy foods, snacks, sweets, increased intake of water/low energy drinks, decreased intake of high energy drinks. Physical activity should be more than 1 hour/day and TV/media consumption less than 1 hour/day.

Main questions are:

Do children differ in intervention and control kindergartens according to their nutrition behaviour? Do children in the intervention kindergartens have a higher physical training than such in the control kindergartens? Data were collected with a standardised questionnaire.

Do children differ in intervention and control kindergartens according to their body mass index?


Options:
A: Arm Label: Parenting Insight; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Parenting Insights | Arm Label: Child Safety Insights; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Child Safety Insights | Intervention Type: BEHAVIORAL; Name: Child Safety Insights; Assigned to Arm(s): Child Safety Insights | Intervention Type: BEHAVIORAL; Name: Parenting Insights; Assigned to Arm(s): Parenting Insight
B: Arm Label: Group One (Two-year Intervention, 2016 Enrollment); Type: EXPERIMENTAL; Interventions: Behavioral: CO-CSA plus Nutrition Education | Arm Label: Group Two (Delayed Two-year Intervention, 2016 Enrollment); Type: EXPERIMENTAL; Interventions: Behavioral: CO-CSA plus Nutrition Education | Arm Label: Group Three (One-year Intervention, 2017 Enrollment); Type: EXPERIMENTAL; Interventions: Behavioral: CO-CSA plus Nutrition Education | Arm Label: Group Four (Delayed One-year Intervention, 2017 Enrollment); Type: EXPERIMENTAL; Interventions: Behavioral: CO-CSA plus Nutrition Education | Intervention Type: BEHAVIORAL; Name: CO-CSA plus Nutrition Education; Assigned to Arm(s): Group Four (Delayed One-year Intervention, 2017 Enrollment), Group One (Two-year Intervention, 2016 Enrollment), Group Three (One-year Intervention, 2017 Enrollment), Group Two (Delayed Two-year Intervention, 2016 Enrollment)
C: Arm Label: National Vaccine Program Plus Radio; Type: EXPERIMENTAL; Interventions: Behavioral: Appropriate complementary feeding messages | Arm Label: Comparison (no intervention); Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Appropriate complementary feeding messages; Assigned to Arm(s): National Vaccine Program Plus Radio
D: Intervention Type: BEHAVIORAL; Name: attitude change; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: adiposity prevention program; Assigned to Arm(s): N/A

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: Behavioral intervention at Kindergarten setting aiming at increased fruit and vegetable consumption, decreased intake of high energy foods, snacks, sweets, increased intake of water/low energy drinks, decreased intake of high energy drinks. Physical activity should be more than 1 hour/day and TV/media consumption less than 1 hour/day.

Main questions are:

Do children differ in intervention and control kindergartens according to their nutrition behaviour? Do children in the intervention kindergartens have a higher physical training than such in the control kindergartens? Data were collected with a standardised questionnaire.

Do children differ in intervention and control kindergartens according to their body mass index?


Options:
A: Intervention Type: BEHAVIORAL; Name: Targeted parental instruction for positive lifestyle change with follow-up calls.; Assigned to Arm(s): N/A
B: Intervention Type: BEHAVIORAL; Name: attitude change; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: adiposity prevention program; Assigned to Arm(s): N/A
C: Intervention Type: BEHAVIORAL; Name: Nutritional and life style counseling; Assigned to Arm(s): N/A
D: Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Intervention group; Type: EXPERIMENTAL; Interventions: Behavioral: Lifestyle intervention | Intervention Type: BEHAVIORAL; Name: Lifestyle intervention; Assigned to Arm(s): Intervention group

Answer: B