Please select the eligibility criteria that correspond to the clinical trial below.
Title: Evaluation of Closed Incision Negative Pressure Device (Prevena) to Prevent Vascular Wound Complications
Brief Summary: The purpose of this study is to determine if the application of a negative pressure dressing intraoperatively (Prevena; KCI, Inc) to vascular groin incisions decreases the wound complication rate in high risk patients.


Options:
A: Inclusion Criteria:

* Patients over 18 years old (men and women).
* To give his consent to participation in the study.
* To have surgical prosthetic repair of large incisional hernia (type W2 or W3).
* Patients admitted to the 6th floor, G tower (Unit of Abdominal Wall surgery).

Exclusion Criteria:

* Patients with immediate reintervention of abdominal surgery (less than 30 days from the first surgery).
* Patients after emergency surgery.
* Patients with biological prosthesis.
* Pregnancy and lactation.
* Hepatic cirrhosis.
B: Inclusion Criteria:

* 30 total patients undergoing panniculectomy alone following massive weight loss
* 30 total patients undergoing formal abdominoplasty (including undermining of skin flaps, rectus fascia plication and liposuction) following massive weight loss
* 30 total non-massive weight loss patients undergoing formal lipo-abdominoplasty
* 30 total patients undergoing ventral hernia repair using acellular dermal matrix
* 30 total patients undergoing bilateral breast reconstruction using acellular dermal matrix with 30 breasts randomized to conventional closed suction (one breast left vs right) and 30 breasts randomized to continuous negative pressure devices (=60 breasts total)

Exclusion Criteria:

* presence of necrotic tissue
* untreated osteomyelitis
* malignancy (except terminal patients for quality of life issues)
* untreated malnutrition
* use on exposed arteries, veins, or organs
* use on non-enteric and unexplored fistulas Special precaution will be taken when using the NPWT device in patients on anticoagulants, exhibiting otherwise difficult hemostasis, or non-adherent patients.
C: Inclusion Criteria:

* All patients undergoing a femoral incision during vascular reconstruction or repair will be considered for study

Exclusion Criteria:

* Emergency procedure
* Unable to give informed consent
D: Inclusion Criteria:

* Written informed consent
* Post-surgical subcutaneous abdominal wound healing impairment
* Minimum wound size eligible for the application of the randomized treatment- Inclusion, randomization, adequate wound pre-treatment (Debridement) and start of therapy within 48 hours after reopening of the wound, diagnosis for nonclosable wound or in case of spontaneous wound dehiscence

Exclusion Criteria:

* Age \< 18
* Noncompliance with study procedures, visit schedule and follow up
* Pregnancy
* Present or nonclosable defect of the abdominal fascia
* Any pre-existing or ongoing organ system failure, that cannot be stabilized or solved by appropriate medical treatment
* Necrotic tissue with eschar present
* Non-enteric and unexplored fistulas
* Malignancy of the wound
* Use of any other device based on the principle of negative pressure wound therapy on the study wound within ≤ 8 days prior to screening
* Competing therapies or procedures
* Simultaneous participation in other clinical trials

Answer: C