Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Fluid Lavage of Open Wounds (FLOW): A Multi-center, Blinded, Factorial Trial Comparing Alternative Irrigating Solutions and Pressures in Patients With Open Fractures
Brief Summary: Open fracture wounds are a constant challenge to orthopaedic surgeons, with infections a common complication. There is currently little evidence as to which is the most effective way to wash out these wounds. This study is a multi-center, prospective, randomized study. The infection rates will be compared between irrigation using high pressure versus low pressure versus gravity flow, and also saline versus a soap solution as the irrigation solution. The results from this study will help to determine the best method of washing out open fractures wounds. In this study, all open wounds will be washed out using methods commonly used by orthopaedic surgeons


Options:
A: Arm Label: High dose manipulation; Type: EXPERIMENTAL; Interventions: Procedure: Spinal Manipulation, Procedure: Pulsed Ultrasound | Arm Label: Moderate dose manipulation; Type: EXPERIMENTAL; Interventions: Procedure: Spinal Manipulation, Procedure: Light Massage, Procedure: Pulsed Ultrasound | Arm Label: Low dose manipulation; Type: EXPERIMENTAL; Interventions: Procedure: Spinal Manipulation, Procedure: Light Massage, Procedure: Pulsed Ultrasound | Arm Label: High dose masssage; Type: OTHER; Interventions: Procedure: Light Massage, Procedure: Pulsed Ultrasound | Intervention Type: PROCEDURE; Name: Spinal Manipulation; Assigned to Arm(s): High dose manipulation, Low dose manipulation, Moderate dose manipulation | Intervention Type: PROCEDURE; Name: Light Massage; Assigned to Arm(s): High dose masssage, Low dose manipulation, Moderate dose manipulation | Intervention Type: PROCEDURE; Name: Pulsed Ultrasound; Assigned to Arm(s): High dose manipulation, High dose masssage, Low dose manipulation, Moderate dose manipulation
B: Arm Label: Saline, gravity flow; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Saline Solution, Procedure: Gravity Flow Irrigation | Arm Label: Saline, Low Pressure; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Saline Solution, Procedure: Low Pressure Irrigation | Arm Label: Saline, High Pressure; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Saline Solution, Procedure: High Pressure | Arm Label: Soap, Gravity Flow; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Soap solution, Procedure: Gravity Flow Irrigation | Arm Label: Soap, low pressure; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Soap solution, Procedure: Low Pressure Irrigation | Arm Label: Soap, high pressure; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Soap solution, Procedure: High Pressure | Intervention Type: PROCEDURE; Name: Saline Solution; Assigned to Arm(s): Saline, High Pressure, Saline, Low Pressure, Saline, gravity flow | Intervention Type: PROCEDURE; Name: Soap solution; Assigned to Arm(s): Soap, Gravity Flow, Soap, high pressure, Soap, low pressure | Intervention Type: PROCEDURE; Name: Gravity Flow Irrigation; Assigned to Arm(s): Saline, gravity flow, Soap, Gravity Flow | Intervention Type: PROCEDURE; Name: Low Pressure Irrigation; Assigned to Arm(s): Saline, Low Pressure, Soap, low pressure | Intervention Type: PROCEDURE; Name: High Pressure; Assigned to Arm(s): Saline, High Pressure, Soap, high pressure
C: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Brief Intervention | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Behavioral: Cognitive Behavioural Therapy | Arm Label: 3; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Seal oil | Arm Label: 4; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Soy oil | Intervention Type: BEHAVIORAL; Name: Brief Intervention; Assigned to Arm(s): 1 | Intervention Type: BEHAVIORAL; Name: Cognitive Behavioural Therapy; Assigned to Arm(s): 2 | Intervention Type: DIETARY_SUPPLEMENT; Name: Seal oil; Assigned to Arm(s): 3 | Intervention Type: DIETARY_SUPPLEMENT; Name: Soy oil; Assigned to Arm(s): 4
D: Intervention Type: BEHAVIORAL; Name: Cognitive-behavioral rehabilitation; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: Traditional primary care; Assigned to Arm(s): N/A

Answer: B