Please select the eligibility criteria that correspond to the clinical trial below.
Title: Nutrition, Allergy, Mucosal Immunology and Intestinal Microbiota (NAMI): Pre-, Peri- and Postnatal Programming and Origins of Disease: Early Targeting the Epidemics of Allergy and Overweight
Brief Summary: Combined programme: Nutrition, Allergy, Mucosal immunology and Intestinal microbiota (NAMI) was created with the objective to reverse the rising trend of chronic inflammatory diseases, such as allergic disease and obesity, by control of the internal and external environments of the infant. To approach this problem, the project aims to characterize

* how immunology is regulated during pregnancy and early infancy,
* how the immune interaction between mother and child is influenced by nutritional and microbial factors, and
* how the regulation is related to disease risk.


Options:
A: Postmenopausal women, aged 50 to 69 years, who consumed 38 percent or more of total calories as fat at baseline.
B: Inclusion Criteria:

* Pregnant women from families with at least one family member having an allergic disease

Exclusion Criteria:

* Women presenting severe immunological or other chronic diseases (rheumatoid arthritis, diabetes, inflammatory bowel disease, thyroid diseases, malignancies etc.)
* Women who cannot be expected to comply with treatment
* Women currently participating or having participated in other clinical trial during the last 2 months prior to the beginning of the intervention.
C: Inclusion Criteria:

* BMI\>27
* age\>40
* History of CHD or diabetes in any age or BMI level

Exclusion Criteria:

* Pregnant or lactating women.
* Active drug or alcohol use or dependence that, in the opinion of the site investigator, would interfere with adherence to study requirements.
* Serum creatinine \> 3 mg/dl.
* Liver dysfunction ( ³ 2 fold level of ALT and AST enzymes).
* Participation in another trial in which active intervention is being received.
* Any intestinal problem that would prevent the patient from eating one of the test diets (for example, gastric stapling that might prevent consumption of vegetables).
D: Inclusion Criteria:

* Ethnicity: All ethnic groups
* Body mass index (BMI) 18.5-39.9 kg/m2
* Suboptimally controlled asthma:
* Diagnosis of asthma on the current medical problem list
* Currently prescribed at least 1 medication for the treatment of asthma
* Physiological evidence of asthma with demonstrable reversibility of airway obstruction, or a specialist's confirmation of asthma diagnosis based on chart review
* Documented history of high asthma-related emergency and/or inpatient encounters or reliever medication usage
* Asthma Control Test: total score \<20 or item score \<3 for any of the first 4 questions regarding symptoms (3-6x/week or more), nighttime awakening (1x/week or more), interference with normal activity (at least some of the time), and rescue medication use for symptom relief (2-3x/week or more)
* Kaiser member for ≥1 year
* PCP approval of study screening
* Able and willing to enroll and provide written informed consent

Exclusion Criteria:

* Intermittent asthma, defined as either seasonal asthma or (daytime asthma symptoms \<2x/week and nocturnal symptoms \<2x/month and no use of long-term control medications)
* Primary diagnosis of COPD (emphysema or chronic bronchitis) on the current medical problem list or suggested by baseline spirometry and smoking history
* Previous diabetes (other than during pregnancy) or diabetes diagnosed as a result of fasting blood glucose or hemoglobin A1c levels obtained at screening
* Previous cardiovascular disease: e.g., coronary heart disease, cerebrovascular disease, peripheral vascular disease, heart failure, or aortic aneurysm
* Diagnosis of cancer (other than non-melanoma skin cancer) that is/was active or treated with radiation or chemotherapy within the past 2 years
* Inflammatory bowel disease, colostomy, malabsorption, or major gastrointestinal resection
* Diagnosis of bipolar or psychotic disorder or hospitalization for psychological or emotional problems within the last 2 years
* Diagnosis of a terminal illness and/or in hospice care
* Fasting LDL cholesterol \>190 mg/dL, triglycerides \>500 mg/dl, fasting blood glucose \>125 mg/dl
* Significant liver enzyme abnormality as indicated by AST or ALT more than 2 times the upper limit of normal or a clinical diagnosis of hepatitis
* Renal insufficiency (GFR\<60 ml/min)
* Current use of insulin or oral hypoglycemic agents
* Use of oral corticosteroids \>5 days/month on average
* Current use of medications for treatment of psychosis or manic-depressive illness
* Current use of prescription or non-prescription weight-loss products or any dietary/herbal supplements and unwillingness to discontinue;
* Inability to speak, read, or understand English at the 6th-grade level or above
* Inability to perform pulmonary function tests by spirometry in a consistent manner
* DASH concordance index \>60%
* Unwillingness to modify current diet
* Current or planned participation in a structured program that overtly focuses on diet and nutrition
* Planning to undergo bariatric surgery during the study period
* Actively attempting to lose weight, or weight change \>15 lbs during prior 3 months
* Consumption of \>21 alcoholic drinks per week, or \>=6 drinks on one occasion twice or more per week, or alcoholism as determined by the Alcohol Use Disorders Identification Test
* Pregnant, lactating, or planning to become pregnant during the study period
* No longer a Kaiser patient or planning to transfer care out of Kaiser or to move out of the area during the study period
* Family/household member of another study participant or of a study staff member
* Enrolled or planning to enroll in another research study that would limit full participation in the study or confound the interpretation of the study's findings
* Investigator discretion for safety or protocol adherence reasons

Answer: B