Please select the eligibility criteria that correspond to the clinical trial below.
Title: Preventing Overweight Using Novel Dietary Strategies (Pounds Lost)
Brief Summary: The purpose of this study is to test the effectiveness for weight loss and weight maintenance of four diets differing in macronutrient composition: moderate in fat (40 percent energy) with two different protein levels (15 percent and 25 percent), and low in fat (20 percent energy), also with 15 percent and 25 percent protein levels. The study is only accepting participants in the Boston, Massachusetts or Baton Rouge, Louisiana area. For further enrollment information in Boston or Baton Rouge, see Eligibility Criteria or Design Narrative.


Options:
A: Inclusion criteria:

* Students in Zhejiang University or working stuff in the Chinese PLA General Hospital
* 18 ≤ age ≤ 35
* Body Mass Index \< 28\*
* Are willing to eat all of the study foods even when full
* Are willing to eat only foods provided
* Are willing to avoid strenuous activity during the 6-mo intervention Exclusion criteria：
* Systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg
* Total cholesterol ≥ 239 mg/dL
* Low-density lipoprotein cholesterol ≥ 159 mg/dL
* Triglycerides ≥ 199 mg/dL
* Blood glucose ≥ 110 mg/dL
* Change in body weight exceeding ± 10% during the prior year
* Energy intake is too low or too high
* Unwillingness or special requirement for diet that could not be modified
* Poor adherence during the recruiting meeting or unsatisfactory completion of keeping food diary or filling questionnaire at any time before randomization
* Eating disorder or any psychosocial or scheduling factors that could impede study outcomes
* Have a history of diagnosed CVD, diabetes, cancer or inflammatory diseases
* Have a history of a mental illness
* Have diagnosed endocrine, pulmonary or hematological disease
* Have diagnosed bowel disease or malabsorption that would prevent the participants from complying with the dietary restrictions of the feeding trial
* Renal or liver insufficiency
* Other chronic disease thought to interfere with the effect of the diet or with participation or adherence
* Current use of supplements or anti-inflammation medications or medications affecting glucose, lipid metabolism and blood pressure
* Smoking or alcoholic beverage intake \>1 times per week
* Current or planned pregnancy prior to end of study, or breast-feeding
* Irregular menstrual cycles
* Have birth control medication
B: Inclusion Criteria:

* Only accepting participants in the Boston, Massachusetts or Baton Rouge, Louisiana area
* Between the ages of 30 - 70
* Willing to modify eating pattern according to instructions
* Overweight or obese and in good health with a BMI of 25-40
* Committed to a long-term weight loss and maintenance program
* Willing to attend multiple weight loss group sessions
* Willing to increase activity level

Exclusion Criteria:

* Pregnant, planning to become pregnant, or are breastfeeding
* Unwilling to participate in the schedule of group sessions and individual visits
* Unstable or recent onset of heart disease or any other serious illness
* Cannot change diet due to medical or other reasons
* Planning to leave the area prior to the anticipated end of participation
* Current participation in another clinical trial with an intervention that affects weight change
* Have diabetes that is treated with insulin or hypoglycemic oral medicines
* Diagnosis of psychiatric or emotional problems within 6 months of study
* Currently have an eating disorder
* Have hypothyroidism
* Have an unstable weight
C: Inclusion Criteria:

* Men or women age 30-65,
* BMI in the range 28-35 kg/m2 for women and 28-40kg/m2 for men.
* At least one of the following components of the metabolic syndrome; fasting triglycerides \> 1,7, fasting glucose 6,0-6,9, HDL-cholesterol \<1,03 (males) or \<1,29 (females), Blood pressure \>130/85 (with or without treatment), diet-treated diabetes mellitus or drug treated hypertension.
* Stable weight range of 4 kg or less the last 12 weeks,
* No major change in physical activity the last 12 weeks

Exclusion Criteria:

* Any symptomatic cardiovascular disease
* Diabetes requiring drug treatment
* Currently on special diet
* Hepatic/renal dysfunction
* Hypothyroidism (unstable)
* GI disorder impairing compliance with diet recommendation,
* History of unstable psychiatric or medical disorder,
* Need of lipid lowering drug,
* Alcohol or drug abuse,
* Participation in drug trial the last 30 days,
* Use of drugs for weight reduction last 12 weeks, pregnancy or planned pregnancy,
* Obesity of known endocrine origin, history of obesity surgery,
* Uncontrolled hypertension (\>160/100),
* Previous participation in \>3 weight reduction programs, or within last 12 months,
* Not willing to be randomized,
* Individual judged to be unable to follow instructions and procedures of the study
D: Inclusion Criteria:

* Subject enrolled in the cohort Nutriep assembled in 2005-2007
* Moderate or severe NAFLD

Exclusion Criteria:

* Middle NAFLD
* Not enrolled in the Nutriep cohort
* Pregnancy

Answer: B