Please select the eligibility criteria that correspond to the clinical trial below.
Title: Impact of Transcranial Direct Current Stimulation (tDCS) on Locomotion and Bipedal Equilibrium in Hemiplegic Patients: a Crossover Randomized Controlled Trial
Brief Summary: The aim of this trial is to quantify the improvement of locomotion and equilibrium induced par tDCS in anode polarity position in post stroke hemiplegic patients.


Options:
A: Inclusion Criteria:

1. persons affected by first supratentorial stroke, whose onset time is 25±7 days;
2. upper limb hemiparesis;
3. cognitive and speech abilities sufficient to understand instructions and to provide informed consent;
4. absence of intense pain due to passive wrist mobilization assessed by VAS \< 3 (range 0-10);
5. ability to provide written informed consent.

Exclusion Criteria:

1. previous epilepsy seizures;
2. severe electroencephalographic anomalies;
3. previous neurosurgery interventions involving metallic elements placement;
4. ongoing anticonvulsant drugs treatment
5. inability to keep sitting posture;
6. severe sensory deficits;
7. general clinical complication preventing delivery of rehabilitation treatment.
B: Inclusion Criteria:

* Adults
* Unilateral stroke
* More than 6 months after stroke
* Ability to walk during 10 minutes without stopping
* Informed consent signed

Exclusion Criteria :

* Patient with pacemaker
* Claustrophobia (unable to perform a magnetic resonance imaging analysis)
* Patient with severe aphasia or severe cognitive disorder interfering the follow-up of the trial
* Neuro-orthopedic surgery history in the last 6 months on the studied paretic lower limb
* Epilepsy history in the last year
* Lack of medical insurance
* Adult patient under the care of a guardian
* Patient with progressive concomitant disease
* Patient with deep brain stimulation treatment (implantation of medical device)
* Patient with implantation of Intracranial metallic clip
* Patient with implantation of Intracranial stent
* Patient with implantation of ventriculoperitoneal derivation
* Patient with implantation of intracerebral or ocular prosthetic materials
* Patient with ferro-magnetic foreign object
* Patient with cochlear implant
* Patient with implantable cardioverter-defibrillator
C: Inclusion Criteria:

* stroke with at least slight deficit

Exclusion Criteria:

* epilepsy
* contraindication to tDCS and/or to fMRI
* presence of metal in the head
* unability to understand / complete behavioural tasks
* chronic intake of alcohol or recreative drugs
* major health condition
* presence of pacemaker
* pregnancy
D: Inclusion Criteria:

* first ever haemorrhagic or ischaemic subcortical stroke more than 9 months prior to study enrollment
* upper extremity impairment of 11-45 on the Fugl-Meyer assessment scale

Exclusion Criteria:

* epilepsy
* neglect
* cognitive impairment
* other neurological or psychiatric diseases
* severe arm pain
* spasticity score \>2 on the Modified Ashworth Scale in the shoulder or elbow
* contraindications to TMS or tDCS (cranial implants, ventricular shunts, pacemakers, intrathecal pumps)
* grip strength \<10kg as measured by a dynamometer
* participation in other interventions or trials targeting stroke motor recovery.

Answer: B