Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Evaluation of Effectiveness of GSK Biologicals' Pneumococcal Conjugate Vaccine 1024850A Against Invasive Disease
Brief Summary: The aim of this study is to assess the effectiveness of GSK Biologicals' pneumococcal conjugate vaccine (GSK1024850A), administered according to different vaccination schedules, against invasive disease caused by S. pneumoniae or H. influenzae as well as vaccine impact on the occurrence of hospital-diagnosed pneumonia cases, tympanostomy tube placement and outpatient antimicrobial prescriptions.

This study will also explore vaccine impact on occurrence of respiratory tract infections (RTIs), including acute otitis media (AOM) in a subset of children in Turku area.


Options:
A: Arm Label: Synflorix + Infanrix hexa Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: GSK Biologicals´ Pneumococcal Conjugate Vaccine GSK1024850A (Synflorix™), Biological: Infanrix™ hexa. | Arm Label: Synflorix + Pediacel Group; Type: EXPERIMENTAL; Interventions: Biological: GSK Biologicals´ Pneumococcal Conjugate Vaccine GSK1024850A (Synflorix™), Biological: Pediacel™ | Arm Label: Prevenar + Pediacel Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: Pediacel™, Biological: Prevenar™ | Intervention Type: BIOLOGICAL; Name: GSK Biologicals´ Pneumococcal Conjugate Vaccine GSK1024850A (Synflorix™); Assigned to Arm(s): Synflorix + Infanrix hexa Group, Synflorix + Pediacel Group | Intervention Type: BIOLOGICAL; Name: Infanrix™ hexa.; Assigned to Arm(s): Synflorix + Infanrix hexa Group | Intervention Type: BIOLOGICAL; Name: Pediacel™; Assigned to Arm(s): Prevenar + Pediacel Group, Synflorix + Pediacel Group | Intervention Type: BIOLOGICAL; Name: Prevenar™; Assigned to Arm(s): Prevenar + Pediacel Group
B: Arm Label: 10Pn3+1-6W- 6M/043 Group; Type: EXPERIMENTAL; Interventions: Biological: Pneumococcal conjugate vaccine GSK1024850A | Arm Label: 10Pn2+1-6W-6M/043 Group; Type: EXPERIMENTAL; Interventions: Biological: Pneumococcal conjugate vaccine GSK1024850A | Arm Label: Ctrl-6W-6M/043 Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: GSK Biologicals' Engerix TM vaccine (Hepatitis B vaccine) | Arm Label: 10Pn7-11M/043 Group; Type: EXPERIMENTAL; Interventions: Biological: Pneumococcal conjugate vaccine GSK1024850A | Arm Label: Ctrl7-11M/043 Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: GSK Biologicals' Engerix TM vaccine (Hepatitis B vaccine) | Arm Label: 10Pn12-18M/043 Group; Type: EXPERIMENTAL; Interventions: Biological: Pneumococcal conjugate vaccine GSK1024850A | Arm Label: Ctrl12-18M/043 Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: GSK Biologicals' Havrix TM vaccine (Hepatitis A vaccine) | Intervention Type: BIOLOGICAL; Name: Pneumococcal conjugate vaccine GSK1024850A; Assigned to Arm(s): 10Pn12-18M/043 Group, 10Pn2+1-6W-6M/043 Group, 10Pn3+1-6W- 6M/043 Group, 10Pn7-11M/043 Group | Intervention Type: BIOLOGICAL; Name: GSK Biologicals' Engerix TM vaccine (Hepatitis B vaccine); Assigned to Arm(s): Ctrl-6W-6M/043 Group, Ctrl7-11M/043 Group | Intervention Type: BIOLOGICAL; Name: GSK Biologicals' Havrix TM vaccine (Hepatitis A vaccine); Assigned to Arm(s): Ctrl12-18M/043 Group
C: Arm Label: 10Pn3+1-6W-6M/053 Group; Type: EXPERIMENTAL; Interventions: Biological: Pneumococcal conjugate vaccine Synflorix (GSK1024850A) | Arm Label: 10Pn2+1-6W-6M/053 Group; Type: EXPERIMENTAL; Interventions: Biological: Pneumococcal conjugate vaccine Synflorix (GSK1024850A) | Arm Label: Ctrl3+1-6W-6M/053 Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: GSK Biologicals' Engerix TM vaccine (Hepatitis B vaccine) | Arm Label: Ctrl2+1-6W-6M/053 Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: GSK Biologicals' Engerix TM vaccine (Hepatitis B vaccine) | Arm Label: 10Pn7-11M/053 Group; Type: EXPERIMENTAL; Interventions: Biological: Pneumococcal conjugate vaccine Synflorix (GSK1024850A) | Arm Label: Ctrl7-11M/053 Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: GSK Biologicals' Engerix TM vaccine (Hepatitis B vaccine) | Arm Label: 10Pn12-18M/053 Group; Type: ACTIVE_COMPARATOR; Interventions: Biological: Pneumococcal conjugate vaccine Synflorix (GSK1024850A) | Arm Label: Ctrl12-18M/053 Group; Type: EXPERIMENTAL; Interventions: Biological: GSK Biologicals' Havrix TM vaccine (Hepatitis A vaccine) | Intervention Type: BIOLOGICAL; Name: Pneumococcal conjugate vaccine Synflorix (GSK1024850A); Assigned to Arm(s): 10Pn12-18M/053 Group, 10Pn2+1-6W-6M/053 Group, 10Pn3+1-6W-6M/053 Group, 10Pn7-11M/053 Group | Intervention Type: BIOLOGICAL; Name: GSK Biologicals' Engerix TM vaccine (Hepatitis B vaccine); Assigned to Arm(s): Ctrl2+1-6W-6M/053 Group, Ctrl3+1-6W-6M/053 Group, Ctrl7-11M/053 Group | Intervention Type: BIOLOGICAL; Name: GSK Biologicals' Havrix TM vaccine (Hepatitis A vaccine); Assigned to Arm(s): Ctrl12-18M/053 Group
D: Arm Label: 2-dose; Type: EXPERIMENTAL; Interventions: Biological: PCV7 | Arm Label: 2+1-dose; Type: EXPERIMENTAL; Interventions: Biological: PCV7 | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BIOLOGICAL; Name: PCV7; Assigned to Arm(s): 2-dose | Intervention Type: BIOLOGICAL; Name: PCV7; Assigned to Arm(s): 2+1-dose

Answer: B