TrialPanorama/Dataset huggingface dataset:
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Simplified Antibiotic Regimens for the Management of Sepsis in Young Infants in First-level Facilities: Randomized Controlled Trial
Brief Summary: This trial evaluates primary care clinic-based simplified antibiotic therapy options for young infants, 0-59 days old in high neonatal mortality settings in peri-urban Karachi where hospital referral is frequently refused by families.


Options:
A: Inclusion Criteria:

* participants consenting for the home-based care model area
* participants who consent for household adequacy survey
* participants who consent from clinic care model area
B: Inclusion Criteria:

* Infants 0-59 days old who are residents of catchment population of the study hospitals
* One or more of the following five signs: severe chest in-drawing, axillary temperature \>37.80C or \<35.50 C, lethargic or less than normal movement, and history of feeding problems (confirmed by poor suck on feeding assessment)
* Family refuses recommended hospitalization or hospitalization otherwise not feasible
* Informed consent by a legal guardian.

Exclusion Criteria:

* Very severe infection/disease characterized by presence of any of the following signs (unconscious, convulsions, unable to feed, apnea, unable to cry, cyanosis, bulging fontanel, major congenital malformations, major bleeding, surgical conditions needing hospital referral, persistent vomiting defined as vomiting following three attempts to feed the baby within ½ hour, and/or physician's suspicion of meningitis)
* Very low birth weight: weight \<1500
* Hospitalization for illness in the last two weeks
* Hospital born infants
* Previous inclusion in the study
C: Inclusion Criteria:

* Participants who give consent to be treated at Health Post by Health extension worker

Exclusion Criteria:

* If Newborn is Critically sick
D: Inclusion Criteria:

* Inclusion Criteria

  * Infants 0-59 days old who are residents of catchment population of the study hospitals or clinics
  * One or more of the following five signs: severe chest in-drawing, axillary temperature \>38.0C or \<35.50 C, movement only when stimulated, and history of feeding problems (confirmed by poor suck on feeding assessment)
  * Family refuses recommended hospitalization or hospitalization otherwise not feasible
  * Informed consent by a legal guardian.
* Exclusion Criteria:

Very severe infection/disease characterized by presence of any of the following signs (unconscious, convulsions, unable to feed, apnea, unable to cry, cyanosis, bulging fontanel, prolonged capillary refill, major congenital malformations, major bleeding, surgical conditions needing hospital referral, persistent vomiting defined as vomiting following three attempts to feed the baby within ½ hour)

* Very low birth weight: weight \<1500
* Hospitalization for illness in the last two weeks
* Previous inclusion in the study

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: A Computer-Assisted Brief Motivational Intervention for Smoking During Pregnancy: The Healthy Pregnancy Project (HPP)
Brief Summary: This study will develop:

1. Develop the computer-based brief intervention and Contingency Management (CM) components, with repeated feedback from experts, prenatal clinic staff, and participants.
2. Recruit 110 pregnant women who are actively smoking, and randomly assign recruited women to Brief Intervention, CM, combined, or control conditions.
3. Conduct follow-up evaluation at 12 weeks post-intervention to measure self-reported smoking, breath carbon monoxide (CO), and urinary cotinine levels.
4. Collect data regarding birth outcomes and evaluate the feasibility of various methods of post-partum follow-up.


Options:
A: Inclusion Criteria:

* at least 18 years
* pregnant, gestation \<= 27 weeks
* cigarette smoking in the past week (even if only one puff)

Exclusion Criteria:

* inability to speak or understand spoken English
* do not intend to carry pregnancy to full term
* frank psychosis
B: Inclusion Criteria:

* Current smoker of at least 10 cigarettes per week and at least 100 cigarettes over the course of a lifetime
* Residents of the study area in Nakhon Nayok province, which includes the six subdistricts of Klong Yai, Chumpon, Bueng San, Pak Phli, Khao Phoem, or Ongkharak

Exclusion Criteria:

* Pregnant
* Plans to leave the study area within the next 12 months
C: Inclusion Criteria:

* Clinical diagnosis of cocaine/methamphetamine dependence
* Smoked cigarettes for at least 3 months
* Currently smoking \> 6 cigarettes/day
* Have an interest in quitting smoking
* Enrolled in outpatient treatment at a participating site

Exclusion Criteria:

* Clinical diagnosis of current alcohol or sedative dependence, bipolar disorder; or a life-time diagnosis of anorexia nervosa or bulimia
* Seeking/receiving treatment for opiate-agonist replacement therapy
* Medical conditions that could compromise participant safety
* Taking medications with known/potential interactions with bupropion
* Hypersensitivity to bupropion, nicotine, or menthol
* Pregnant or breastfeeding
* Abnormal ECG
* Recent smoking cessation treatment
* Use of tobacco products other than cigarettes in the past week
* Likely to enter residential/inpatient treatment within 10 weeks
* Have all stimulant-positive urine drug screens during screening/baseline
D: Inclusion Criteria:

* Enrolled full or part-time at one of the participating campuses
* Smoke at least 10 days per month
* Intending to be in school for the entire academic year (i.e., next 2 semesters)
* Willing to provide a baseline urine sample to verify smoking status
* Able to read English
* Access to working telephone for phone-based counseling and surveys
* Access to a computer with internet access
* Provide written informed consent

Exclusion Criteria:

* Prior to concurrent enrollment in this study through a different college campus or in a different academic year
* those who have used a cessation aid within the last 7 days
* pregnant or planning to become pregnant in next 3 months

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: A Computer-Assisted Brief Motivational Intervention for Smoking During Pregnancy: The Healthy Pregnancy Project (HPP)
Brief Summary: This study will develop:

1. Develop the computer-based brief intervention and Contingency Management (CM) components, with repeated feedback from experts, prenatal clinic staff, and participants.
2. Recruit 110 pregnant women who are actively smoking, and randomly assign recruited women to Brief Intervention, CM, combined, or control conditions.
3. Conduct follow-up evaluation at 12 weeks post-intervention to measure self-reported smoking, breath carbon monoxide (CO), and urinary cotinine levels.
4. Collect data regarding birth outcomes and evaluate the feasibility of various methods of post-partum follow-up.


Options:
A: Inclusion Criteria:

* Pregnant women
* current cigarette smoker (smoked \>1 cigarette in the past 7 days)
* 18 years old or older
* Willing to consider altering their smoking behavior during their pregnancy

Exclusion Criteria:

* More than 26 weeks' gestation at study entry
* No telephone access
* Not planning to live in New England for 1 year
* Unable to read and speak English
B: Inclusion Criteria:

* Pregnant women
* current cigarette smoker (smoked \>5 cigarettes in the past 7 days)
* 18 years old or older

Exclusion Criteria:

* More than 24 weeks' gestation at study entry
* No telephone access
* Not planning to live in Athens for 1 year
* Unable to read and speak Greek
* Alcoholics
* Use of drug substances
* Depression
C: Inclusion Criteria:

* at least 18 years
* pregnant, gestation \<= 27 weeks
* cigarette smoking in the past week (even if only one puff)

Exclusion Criteria:

* inability to speak or understand spoken English
* do not intend to carry pregnancy to full term
* frank psychosis
D: Inclusion Criteria:

* Pregnant and less than 25 weeks gestation
* Smoking at least 5 cigarettes per day pre-pregnancy
* Smoking at least 1 cigarette on a typical day during pregnancy
* Aged 16 or over
* Agrees to accept information to assist cessation
* Has own or has primary use of a mobile phone
* Familiar with sending and receiving text messages
* Able to understand written English (text messages are in English only) and consent issues explained in English.
* Able to give informed consent

Exclusion Criteria:

•Already enrolled in another text service to assist smoking cessation

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: A Reduced Carbohydrate Diet Intervention for PCOS
Brief Summary: Polycystic ovary syndrome (PCOS) affects 5-10% of women of reproductive age, and is associated with infertility, risk for obesity and type 2 diabetes, and impaired quality of life. The elevated insulin characteristic of PCOS is likely to play a major role in its symptoms. Manipulation of dietary carbohydrate quantity and quality (glycemic load; GL) may lower insulin and improve both reproductive and metabolic outcomes. The purpose of this study is to determine if a lower GL diet intervention is more effective than a standard (STD) diet in improving reproductive and metabolic outcomes of women with PCOS in the absence of weight loss.


Options:
A: Inclusion Criteria:

* PCOS
* Anovulatory infertility
* Obesity (BMI \>30)

Exclusion Criteria:

* Age \<18 or \>35 years
* Neoplastic, metabolic, hepatic, renal, and cardiovascular disorders or other concurrent medical illnesses
* Hypothyroidism, hyperprolactinemia, Cushing's syndrome, and non-classical congenital adrenal hyperplasia
* Current or previous (within the last six months) use of oral contraceptives, glucocorticoids, antiandrogens, ovulation induction agents, antidiabetic and anti-obesity drugs or other drugs know to affect sex hormone levels, carbohydrate metabolism, or appetite
* Organic pelvic diseases, previous pelvic surgery, suspected peritoneal factor infertility, tubal or male factor infertility or sub-fertility
B: Inclusion Criteria:

* To get the diagnosis polycystic ovary syndrome (PCOS), ultrasonography should reveal at least 1 ovary with PCO according to the Rotterdam diagnostic criteria as well as one of the following two symptoms:

  1. Anovulation/oligoovulation defined as ≥ 35 days during the last year
  2. Clinical signs of hyperandrogenism (hirsutism, acne)

Exclusion Criteria:

* Cardiovascular disease
* Diabetes mellitus
* Other endocrine disease (congenital adrenal hyperplasia, androgen producing tumour, Cushing's syndrome)
* Estrogen/gestagen treatment during the last 3 months
* Breast-feeding the last 6 months
* Antiandrogen treatment the last 3 months
C: Inclusion Criteria:

* Diagnosed with PCOS
* Body mass index 18.5-35 kg/m2

Exclusion Criteria:

* Cushing's syndrome
* Type 1 or 2 diabetes
* Self-reported claustrophobia
* Androgenic tumors or adrenal hyperplasia
* Hyperprolactinemia
* Implanted metal items
* Use of metformin or other diabetes drug
* Women using oral contraceptives will not be excluded, but will be required to discontinue use of these agents 3 months prior to testing.
D: Inclusion Criteria:

* Woman (European Caucasian)
* PCOS
* BMI = or \> 35

Exclusion Criteria:

* Cushing syndrome
* Adrenal hyperplasia
* Androgen-producing tumors
* Anovulation caused by hyperprolactinemia
* Pregnancy, breast feeding
* Use of oral contraceptives/hormone treatment/insulin-sensitizing agents

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Impact of Decision Aids to Enhance Shared Decision Making for Diabetes
Brief Summary: The proposed trial seeks to determine the impact of patient decision aids versus usual care on measures of patient involvement in decision-making, diabetes care processes, medication adherence, glycemic and cardiovascular risk factor control, and resource utilization in nonurban practices in the Midwestern United States. Upon completion of this trial, the investigators will have new knowledge about both the effectiveness of diabetes decision aids in nonacademic nonurban practices and about the processes that promote or inhibit the successful implementation of patient decision aids in such practices.


Options:
A: Inclusion Criteria:

* African American
* Uncontrolled Hypertension
* at least 3 practice visits in the past 2 years
* One lipid panel since 2005

Exclusion Criteria:

* No recent lipid panel
* Kept less than 60% of primary care visits in the prior 2 years
B: Inclusion Criteria:

* Primary care provider is participating in trial
* Are an adult (≥ 18 years) with type 2 diabetes
* English speaking
* Recognize their primary care provider as their main diabetes care provider
* Declare being available for follow-up for six months after treatment decision

Exclusion Criteria:

- Have major barriers to provide written informed consent and to participate in shared decision making (i.e., severe vision or hearing impairment, cognitive impairment, non-English speaking)

Additional Inclusion Criteria for Diabetes Medication:

* Have a clinical diagnosis of type 2 diabetes for one year or more (c-peptide test is not required)
* Use 0, 1, or 2 oral hypoglycemic agents at maximum doses
* Have stable but inadequate glycemic control or worsening glycemic control as identified by their most recent HbA1c measure (within 12 months of the time of eligibility over 7.3%
* Be identified by provider as a medically-appropriate candidate for diabetes medications, (i.e., have not contraindications to taking the medications, e.g., allergy).

Additional Exclusion Criteria for Diabetes Medication:

- Use insulin therapy.

Additional Inclusion Criteria for Cardiovascular Medication:

* Have a clinical diagnosis of type 2 diabetes for any duration (c-peptide test is not required).
* Be identified by provider as a medically-appropriate candidate for statins, (i.e., have not contraindications to taking the medications, e.g., allergy).

Additional Exclusion Criteria for Cardiovascular Medication:

- Use a statin currently.
C: Inclusion Criteria:

* all citizens living in Randers Municipality aged 30-49 on 1 January 2012, identified in the Danish Civil Registers (DCR) and randomised for health check in 2013 or 2017.

Exclusion Criteria:

* Terminal illness, reported by their GP is exclusion criteria for receiving invitation.
D: Inclusion Criteria:

* All patients in primary care referred to Diabetes Educator

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Treating Overweight Youth: A Family Based Approach in Primary Care
Brief Summary: The goal of this study is to test, in the primary care setting, the efficacy of an innovative intervention program for children aged 2-5 years with a BMI over the 85th percentile and one overweight parent (BMI \>27 kg/m2.


Options:
A: Inclusion Criteria:

* 2-5 year old with a BMI greater than the 85th% for age and sex
* one overweight parent (BMI\>27kg/m2)
* child with normal developmental milestones
* history of adherence to 90% of scheduled primary care visits
* parent must be at 5th grade reading and speaking of English language or the spanish language
* no plans on moving out of the area for the 2 years subsequent to enrollment

Exclusion Criteria:

* child with a height 2 SD below the mean for age and sex and/or pathological growth velocity
* SGA
* any chronic disorders influencing energy intake and/or growth
* any orthopedic disorder preventing the child or the parent from ambulation normally and performing the activity prescribed by the program
* any medication known to have the potential of affecting weight changes
* parent or child with psychiatric and/or eating disorder
* participating mother who is pregnant or planning a pregnancy
* parent being acquainted with the parent of a previously randomized study participant
B: Inclusion Criteria:

* one parent of a 3-6 year old child with a BMI greater than or equal to the 85th percentile
* Internet access
* English speaking

Exclusion Criteria:

* Children with a developmental disorder
* Children with a chronic underlying disease that may contribute to obesity
* Children taking medication that may interfere with a healthy weight
C: Inclusion Criteria:

* 85th - 97th percentile BMI
* parent/care giver ability to converse in English
* working telephone

Exclusion Criteria:

* child under current subspecialty care for overweight/obesity
* child currently taking weight-altering medication (at enrollment)
D: Inclusion Criteria:

* Age 2.0 through 5.9 years receiving primary care in a multi-site group practice
* BMI \> 95th percentile for age and sex, or 85th - 95th percentile if at least one parent is overweight

Exclusion Criteria:

* Child currently enrolled in a formal weight management program
* Child is in foster care
* Chronic conditions that may limit our ability to measure height and weight or that may interfere with their growth, physical activity, or dietary recommendations

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Activity, Gait, and Efficacy (AGE II): Functional Limitations and Quality of Life
Brief Summary: The purpose of this study is to test the effectiveness of a DVD-delivered, home-based, six-month physical activity intervention for older adults.

A comparative effectiveness study of the FlexToBa DVD exercise program will be conducted in 2014.


Options:
A: Inclusion Criteria:

* Ability to speak and read English
* Current patient of a physician participating in this study (if selecting a new physician, may deliberately select one that is involved in the study, in order to participate)
* Ability to complete all written surveys
* Accessible for follow-up telephone surveys
* Ability to undergo exercise testing

Exclusion Criteria:

* Currently participating in another research study
* Planning to move out of the Philadelphia area
* Unable to walk without pain
* Pregnant or planning to become pregnant in the year following study entry
* Excessive drinking
* Coronary heart disease
* Congestive heart failure
* Peripheral vascular disease
* Cerebrovascular disease
* Chronic obstructive pulmonary disease
* Arrhythmia
* Recurrent seizures
* Dizziness
* Balance problems
* Psychoses
B: Inclusion Criteria:

* Sedentary lifestyle at work and/or during leisure time
* Intend to be physically active
* Female, age \>25 to 69
* Access to a home telephone or a mobile phone
* Speak and read English

Exclusion Criteria:

* Known medical conditions or other physical problems that need special attention in an exercise program
* Plan a trip abroad during the first 4 months of the study period.
* Pregnant/Delivered a baby during the last 6 months
* Known severe hearing or speech problem
* Body Mass Index (BMI) \> 43.0 kg/m2
* Currently participate in lifestyle modification programs or research studies that may potentially confound the results of the study
* History of bariatric surgery or future plans for bariatric surgery in the next 12 months
C: Inclusion Criteria:

* Pakistani background
* 25-55 year old
* Physically inactive

Exclusion Criteria:

* Diabetes
* heart condition
* medication that could affect the results
D: Inclusion Criteria:

* being non-active, defined as reporting not engaging in regular activity (30 minutes accumulated per day) on more than two days of the week in the prior six months;
* aged 65 - 85 years;
* capable of participation in a program of flexibility,
* toning and balance without exacerbating any pre-existing conditions;
* able to obtain medical clearance for physical activity.

Exclusion Criteria:

* self-reported physical activity on a regular basis within the last six months (2 times or more per week);
* any physical disability that strictly prohibits stretching, strengthening and balance exercises;
* no regular access to a television;
* unable to successfully answer 21 out of 39 questions on the Telephone Interview of Cognitive Status questionnaire (TICS-M).

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Activity, Gait, and Efficacy (AGE II): Functional Limitations and Quality of Life
Brief Summary: The purpose of this study is to test the effectiveness of a DVD-delivered, home-based, six-month physical activity intervention for older adults.

A comparative effectiveness study of the FlexToBa DVD exercise program will be conducted in 2014.


Options:
A: Inclusion Criteria:

* Pakistani background
* 25-55 year old
* Physically inactive

Exclusion Criteria:

* Diabetes
* heart condition
* medication that could affect the results
B: Inclusion Criteria:

* Adults between the ages of 50 and 70;
* Have HealthPartners insurance for 11 out of the past 12 months;
* Engage in moderate physical activity for a total of 30 minutes at least two days per week;
* Have increased activity level in the past year.

Exclusion Criteria:

* Modified Charlson scores \>=3 (calculated using prior year diagnoses);
* Nonskin cancer;
* Congestive heart failure;
* Coronary heart disease;
* Psychotic Illness;
* Substance abuse;
* Terminal illness.
C: Inclusion Criteria:

* being non-active, defined as reporting not engaging in regular activity (30 minutes accumulated per day) on more than two days of the week in the prior six months;
* aged 65 - 85 years;
* capable of participation in a program of flexibility,
* toning and balance without exacerbating any pre-existing conditions;
* able to obtain medical clearance for physical activity.

Exclusion Criteria:

* self-reported physical activity on a regular basis within the last six months (2 times or more per week);
* any physical disability that strictly prohibits stretching, strengthening and balance exercises;
* no regular access to a television;
* unable to successfully answer 21 out of 39 questions on the Telephone Interview of Cognitive Status questionnaire (TICS-M).
D: Inclusion Criteria:

* Sedentary lifestyle at work and/or during leisure time
* Intend to be physically active
* Female, age \>25 to 69
* Access to a home telephone or a mobile phone
* Speak and read English

Exclusion Criteria:

* Known medical conditions or other physical problems that need special attention in an exercise program
* Plan a trip abroad during the first 4 months of the study period.
* Pregnant/Delivered a baby during the last 6 months
* Known severe hearing or speech problem
* Body Mass Index (BMI) \> 43.0 kg/m2
* Currently participate in lifestyle modification programs or research studies that may potentially confound the results of the study
* History of bariatric surgery or future plans for bariatric surgery in the next 12 months

Answer: C