Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase 2a, Randomized, Controlled, Observer Blind, Age De-Escalation, Multicenter and Multinational Study of the Safety, Reactogenicity and Immunogenicity of the NVGH Glycoconjugate Vaccine Against S. Typhi in Adults, Children, Older Infants and Infants
Brief Summary: This phase 2 trial is aimed to obtain information on the safety and immunogenicity of the Vi-CRM197 in subjects from various age groups in India and Pakistan where Typhoid Fever is highly endemic and an efficacious vaccine against this disease is very much needed.


Options:
A: Arm Label: Vi-CRM, Adults; Type: EXPERIMENTAL; Interventions: Biological: Vi-CRM197 vaccine | Arm Label: Vi-PS, Adults; Type: ACTIVE_COMPARATOR; Interventions: Biological: Vi Polysaccharide (PS) vaccine | Arm Label: Vi-CRM, Children; Type: EXPERIMENTAL; Interventions: Biological: Vi-CRM197 vaccine | Arm Label: Vi-PS, Children; Type: ACTIVE_COMPARATOR; Interventions: Biological: Vi Polysaccharide (PS) vaccine, Biological: Pneumococcal conjugate vaccine | Arm Label: Vi-CRM, Older infants; Type: EXPERIMENTAL; Interventions: Biological: Vi-CRM197 vaccine | Arm Label: PNC13, Older infants; Type: ACTIVE_COMPARATOR; Interventions: Biological: Pneumococcal conjugate vaccine | Arm Label: Vi-CRM, Infants; Type: EXPERIMENTAL; Interventions: Biological: Vi-CRM197 vaccine | Arm Label: PNC13, Infants; Type: ACTIVE_COMPARATOR; Interventions: Biological: Pneumococcal conjugate vaccine | Intervention Type: BIOLOGICAL; Name: Vi-CRM197 vaccine; Assigned to Arm(s): Vi-CRM, Adults, Vi-CRM, Children, Vi-CRM, Infants, Vi-CRM, Older infants | Intervention Type: BIOLOGICAL; Name: Vi Polysaccharide (PS) vaccine; Assigned to Arm(s): Vi-PS, Adults, Vi-PS, Children | Intervention Type: BIOLOGICAL; Name: Pneumococcal conjugate vaccine; Assigned to Arm(s): PNC13, Infants, PNC13, Older infants, Vi-PS, Children
B: Arm Label: M01ZH09 vaccine; Type: EXPERIMENTAL; Interventions: Biological: M10ZH09 vaccine | Arm Label: Vaccine placebo; Type: PLACEBO_COMPARATOR; Interventions: Biological: Vaccine placebo (excipients only) | Arm Label: Ty21a vaccine; Type: OTHER; Interventions: Biological: Ty21a | Intervention Type: BIOLOGICAL; Name: Vaccine placebo (excipients only); Assigned to Arm(s): Vaccine placebo | Intervention Type: BIOLOGICAL; Name: Ty21a; Assigned to Arm(s): Ty21a vaccine | Intervention Type: BIOLOGICAL; Name: M10ZH09 vaccine; Assigned to Arm(s): M01ZH09 vaccine
C: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Biological: Typhoid Vi vaccine | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Biological: Hepatitis A vaccine | Intervention Type: BIOLOGICAL; Name: Typhoid Vi vaccine; Assigned to Arm(s): 1 | Intervention Type: BIOLOGICAL; Name: Hepatitis A vaccine; Assigned to Arm(s): 2
D: Arm Label: NVGH Vi-CRM197 conjugate vaccine 12.5 mcg; Type: EXPERIMENTAL; Interventions: Biological: NVGH Vi-CRM197 12.5 mcg | Arm Label: NVGH Vi-CRM197 conjugate vaccine 5 mcg; Type: EXPERIMENTAL; Interventions: Biological: NVGH Vi-CRM197 5.0 mcg | Arm Label: NVGH Vi-CRM197 conjugate vaccine 1.25 mcg; Type: EXPERIMENTAL; Interventions: Biological: NVGH Vi-CRM197 1.25 mcg | Arm Label: Typherix; Type: ACTIVE_COMPARATOR; Interventions: Biological: Vi-polysaccharide vaccine | Intervention Type: BIOLOGICAL; Name: NVGH Vi-CRM197 12.5 mcg; Assigned to Arm(s): NVGH Vi-CRM197 conjugate vaccine 12.5 mcg | Intervention Type: BIOLOGICAL; Name: NVGH Vi-CRM197 5.0 mcg; Assigned to Arm(s): NVGH Vi-CRM197 conjugate vaccine 5 mcg | Intervention Type: BIOLOGICAL; Name: NVGH Vi-CRM197 1.25 mcg; Assigned to Arm(s): NVGH Vi-CRM197 conjugate vaccine 1.25 mcg | Intervention Type: BIOLOGICAL; Name: Vi-polysaccharide vaccine; Assigned to Arm(s): Typherix

Answer: A