Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Surfactant Positive Airway Pressure and Pulse Oximetry Trial (SUPPORT) in Extremely Low Birth Weight Infants
Brief Summary: This study compared the use of continuous positive airway pressure initiated at birth with the early administration of surfactant administered through a tube in the windpipe within 1 hour of birth for premature infants born at 24 to 27 weeks gestation. In addition, these infants within 2 hours of birth, had a special pulse oximeter placed to continuously monitor their oxygen saturation in two different target ranges (85-89% or 91-95%). This study helped determine whether or not these two management strategies affect chronic lung disease and survival of premature infants.


Options:
A: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Device: Surfactant administered via Laryngeal Mask Airway (LMA) | Arm Label: 2; Type: OTHER; Interventions: Other: standard of care (nasal CPAP and supplemental oxygen) | Intervention Type: DEVICE; Name: Surfactant administered via Laryngeal Mask Airway (LMA); Assigned to Arm(s): 1 | Intervention Type: OTHER; Name: standard of care (nasal CPAP and supplemental oxygen); Assigned to Arm(s): 2
B: Arm Label: Supraglottic airway; Type: EXPERIMENTAL; Interventions: Device: Supraglottic airway | Arm Label: Face-mask; Type: ACTIVE_COMPARATOR; Interventions: Device: Face-mask | Intervention Type: DEVICE; Name: Supraglottic airway; Assigned to Arm(s): Supraglottic airway | Intervention Type: DEVICE; Name: Face-mask; Assigned to Arm(s): Face-mask
C: Arm Label: Surfactant and Low Oxygen; Type: EXPERIMENTAL; Interventions: Drug: Surfactant, Drug: Supplemental oxygen with target saturation of 85 to 89% | Arm Label: Surfactant and High Oxygen; Type: EXPERIMENTAL; Interventions: Drug: Surfactant, Drug: Supplemental oxygen with target saturation of 91 to 95% | Arm Label: CPAP and Low Oxygen; Type: EXPERIMENTAL; Interventions: Device: Continuous Positive Airway Pressure (CPAP), Drug: Supplemental oxygen with target saturation of 85 to 89% | Arm Label: CPAP and High Oxygen; Type: EXPERIMENTAL; Interventions: Device: Continuous Positive Airway Pressure (CPAP), Drug: Supplemental oxygen with target saturation of 91 to 95% | Intervention Type: DRUG; Name: Surfactant; Assigned to Arm(s): Surfactant and High Oxygen, Surfactant and Low Oxygen | Intervention Type: DEVICE; Name: Continuous Positive Airway Pressure (CPAP); Assigned to Arm(s): CPAP and High Oxygen, CPAP and Low Oxygen | Intervention Type: DRUG; Name: Supplemental oxygen with target saturation of 85 to 89%; Assigned to Arm(s): CPAP and Low Oxygen, Surfactant and Low Oxygen | Intervention Type: DRUG; Name: Supplemental oxygen with target saturation of 91 to 95%; Assigned to Arm(s): CPAP and High Oxygen, Surfactant and High Oxygen
D: Arm Label: Endotracheal intubation; Type: ACTIVE_COMPARATOR; Interventions: Device: Endotracheal intubation, Drug: remifentanil | Arm Label: Laryngeal mask airway; Type: EXPERIMENTAL; Interventions: Device: Laryngeal mask airway | Intervention Type: DEVICE; Name: Endotracheal intubation; Assigned to Arm(s): Endotracheal intubation | Intervention Type: DEVICE; Name: Laryngeal mask airway; Assigned to Arm(s): Laryngeal mask airway | Intervention Type: DRUG; Name: remifentanil; Assigned to Arm(s): Endotracheal intubation

Answer: C