TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Efficacy of Acupuncture for Chronic Low Back Pain
Brief Summary: This is a trial to clarify the extent to which acupuncture needling can diminish the effect of chronic back pain on patient functioning and symptoms.


Options:
A: Arm Label: Acupuncture 1; Type: EXPERIMENTAL; Interventions: Other: Acupuncture 1 | Arm Label: Acupuncture 2; Type: ACTIVE_COMPARATOR; Interventions: Other: Acupuncture 2 | Intervention Type: OTHER; Name: Acupuncture 1; Assigned to Arm(s): Acupuncture 1 | Intervention Type: OTHER; Name: Acupuncture 2; Assigned to Arm(s): Acupuncture 2
B: Arm Label: Usual care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: non needle control; Type: PLACEBO_COMPARATOR; Interventions: Procedure: Accupuncture | Arm Label: Acupuncture - Standardized Points; Type: SHAM_COMPARATOR; Interventions: Procedure: Accupuncture | Arm Label: Accupunture - Experimental Points; Type: EXPERIMENTAL; Interventions: Procedure: Accupuncture | Intervention Type: PROCEDURE; Name: Accupuncture; Assigned to Arm(s): Accupunture - Experimental Points, Acupuncture - Standardized Points, non needle control
C: Arm Label: Usual care; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Usual care | Arm Label: Integrative care; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Integrative care | Intervention Type: PROCEDURE; Name: Integrative care; Assigned to Arm(s): Integrative care | Intervention Type: PROCEDURE; Name: Usual care; Assigned to Arm(s): Usual care
D: Arm Label: French ear acupuncture; Type: EXPERIMENTAL; Interventions: Device: French ear acupuncture | Arm Label: Sham Ultrasound; Type: PLACEBO_COMPARATOR; Interventions: Other: Sham Ultrasound | Intervention Type: DEVICE; Name: French ear acupuncture; Assigned to Arm(s): French ear acupuncture | Intervention Type: OTHER; Name: Sham Ultrasound; Assigned to Arm(s): Sham Ultrasound

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Efficacy of Acupuncture for Chronic Low Back Pain
Brief Summary: This is a trial to clarify the extent to which acupuncture needling can diminish the effect of chronic back pain on patient functioning and symptoms.


Options:
A: Intervention Type: DRUG; Name: Monovalent Influenza Subunit Virion (H5N1) Vaccine, A/Indonesia/05/2005; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: VRC-AViDNA036-00-VP; Assigned to Arm(s): N/A
B: Arm Label: Vitamin E + selenium placebo; Type: EXPERIMENTAL; Interventions: Drug: Vitamin E, Other: selenium placebo | Arm Label: Selenium + vitamin E placebo; Type: EXPERIMENTAL; Interventions: Drug: Selenium, Other: Vitamin E placebo | Arm Label: Vitamin E + selenium; Type: EXPERIMENTAL; Interventions: Drug: Vitamin E, Drug: Selenium | Arm Label: Vitamin E placebo + selenium placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Vitamin E placebo, Other: selenium placebo | Intervention Type: DRUG; Name: Vitamin E; Assigned to Arm(s): Vitamin E + selenium, Vitamin E + selenium placebo | Intervention Type: DRUG; Name: Selenium; Assigned to Arm(s): Selenium + vitamin E placebo, Vitamin E + selenium | Intervention Type: OTHER; Name: Vitamin E placebo; Assigned to Arm(s): Selenium + vitamin E placebo, Vitamin E placebo + selenium placebo | Intervention Type: OTHER; Name: selenium placebo; Assigned to Arm(s): Vitamin E + selenium placebo, Vitamin E placebo + selenium placebo
C: Arm Label: Fecal Occult Blood Test; Type: ACTIVE_COMPARATOR; Interventions: Other: Fecal occult blood test | Arm Label: Virtual Colonoscopy; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Virtual colonoscopy | Arm Label: Optical Colonoscopy; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Optical colonoscopy | Intervention Type: OTHER; Name: Fecal occult blood test; Assigned to Arm(s): Fecal Occult Blood Test | Intervention Type: PROCEDURE; Name: Virtual colonoscopy; Assigned to Arm(s): Virtual Colonoscopy | Intervention Type: PROCEDURE; Name: Optical colonoscopy; Assigned to Arm(s): Optical Colonoscopy
D: Arm Label: Usual care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: non needle control; Type: PLACEBO_COMPARATOR; Interventions: Procedure: Accupuncture | Arm Label: Acupuncture - Standardized Points; Type: SHAM_COMPARATOR; Interventions: Procedure: Accupuncture | Arm Label: Accupunture - Experimental Points; Type: EXPERIMENTAL; Interventions: Procedure: Accupuncture | Intervention Type: PROCEDURE; Name: Accupuncture; Assigned to Arm(s): Accupunture - Experimental Points, Acupuncture - Standardized Points, non needle control

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Test the Safety and Efficacy of Lipitor (Atorvastatin) in Reducing the Progression of Carotid IMT in Early Childhood SLE
Brief Summary: The purpose of this study is:

1. To assess the efficacy of a lipid-lowering agent (atorvastatin) on the development of atherosclerosis that predisposes children with SLE to cardiovascular events in adulthood.
2. To assess the safety of intermediate-term (36 months) treatment of children and young adults with atorvastatin.
3. To further characterize the course of SLE in children and young adults, by establishing a cohort of pediatric SLE patients to be followed prospectively.
4. To establish a mechanism for conducting clinical trials in rare pediatric rheumatic diseases using the Children's Arthritis and Rheumatology Research Alliance (CARRA).


Options:
A: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: Atorvastatin | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Atorvastatin; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): 2
B: Intervention Type: DRUG; Name: Atorvastatin; Assigned to Arm(s): N/A
C: Arm Label: Cohort 1; Type: EXPERIMENTAL; Interventions: Drug: REGN727, Drug: Placebo | Arm Label: Cohort 2; Type: EXPERIMENTAL; Interventions: Drug: REGN727, Drug: Placebo | Arm Label: Cohort 3; Type: EXPERIMENTAL; Interventions: Drug: REGN727, Drug: Placebo | Arm Label: Cohort 4; Type: EXPERIMENTAL; Interventions: Drug: REGN727, Drug: Placebo | Intervention Type: DRUG; Name: REGN727; Assigned to Arm(s): Cohort 1, Cohort 2, Cohort 3, Cohort 4 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Cohort 1, Cohort 2, Cohort 3, Cohort 4
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: Atorvastatin | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo atorvastatin | Intervention Type: DRUG; Name: Atorvastatin; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: Placebo atorvastatin; Assigned to Arm(s): 2

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: CARE: A Randomized Trial of Colpopexy and Urinary Reduction Efforts
Brief Summary: Pelvic organ prolapse occurs when the muscles holding pelvic organs (e.g., the uterus or bladder) weaken and the organs fall or slide down into the vagina. Pelvic organ prolapse can be corrected with surgery. However, women who have this surgery may develop urinary incontinence. This study will determine how doctors can predict this problem and whether an additional surgical procedure at the time of prolapse surgery can prevent the development of urinary incontinence.


Options:
A: Arm Label: Anterior colporrhaphy; Type: ACTIVE_COMPARATOR; Interventions: Procedure: anterior vaginal repair (colporrhaphy), Procedure: abdominal paravaginal defect repair | Arm Label: Paravaginal defect repair; Type: ACTIVE_COMPARATOR; Interventions: Procedure: anterior vaginal repair (colporrhaphy), Procedure: abdominal paravaginal defect repair | Intervention Type: PROCEDURE; Name: anterior vaginal repair (colporrhaphy); Assigned to Arm(s): Anterior colporrhaphy, Paravaginal defect repair | Intervention Type: PROCEDURE; Name: abdominal paravaginal defect repair; Assigned to Arm(s): Anterior colporrhaphy, Paravaginal defect repair
B: Arm Label: Polypropylene Mesh; Type: ACTIVE_COMPARATOR; Interventions: Device: Polypropylene mesh (Polyform by Boston Scientific) | Arm Label: Anterior Colporrhaphy; Type: PLACEBO_COMPARATOR; Interventions: Procedure: Anterior Colporrhaphy | Arm Label: Porcine Dermis; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Porcine Dermis (Pelvicol by CRBard) | Intervention Type: DEVICE; Name: Polypropylene mesh (Polyform by Boston Scientific); Assigned to Arm(s): Polypropylene Mesh | Intervention Type: PROCEDURE; Name: Porcine Dermis (Pelvicol by CRBard); Assigned to Arm(s): Porcine Dermis | Intervention Type: PROCEDURE; Name: Anterior Colporrhaphy; Assigned to Arm(s): Anterior Colporrhaphy
C: Arm Label: Abdominal Sacral Colpopexy with no Burch colposuspension; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Abdominal Sacral Colpopexy with Burch Colposuspension; Type: EXPERIMENTAL; Interventions: Procedure: Burch urethropexy at time of sacrocolpopexy | Intervention Type: PROCEDURE; Name: Burch urethropexy at time of sacrocolpopexy; Assigned to Arm(s): Abdominal Sacral Colpopexy with Burch Colposuspension
D: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Anterior colporrhaphy | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Procedure: Anterior PROLIFT | Intervention Type: PROCEDURE; Name: Anterior colporrhaphy; Assigned to Arm(s): 1 | Intervention Type: PROCEDURE; Name: Anterior PROLIFT; Assigned to Arm(s): 2

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: CARE: A Randomized Trial of Colpopexy and Urinary Reduction Efforts
Brief Summary: Pelvic organ prolapse occurs when the muscles holding pelvic organs (e.g., the uterus or bladder) weaken and the organs fall or slide down into the vagina. Pelvic organ prolapse can be corrected with surgery. However, women who have this surgery may develop urinary incontinence. This study will determine how doctors can predict this problem and whether an additional surgical procedure at the time of prolapse surgery can prevent the development of urinary incontinence.


Options:
A: Arm Label: Abdominal Sacral Colpopexy with no Burch colposuspension; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Abdominal Sacral Colpopexy with Burch Colposuspension; Type: EXPERIMENTAL; Interventions: Procedure: Burch urethropexy at time of sacrocolpopexy | Intervention Type: PROCEDURE; Name: Burch urethropexy at time of sacrocolpopexy; Assigned to Arm(s): Abdominal Sacral Colpopexy with Burch Colposuspension
B: Arm Label: Abdominal Sacral Colpopexy with no Burch colposuspension; Type: N/A; Interventions: N/A | Arm Label: Abdominal Sacral Colpopexy with Burch Colposuspension; Type: N/A; Interventions: N/A
C: Intervention Type: PROCEDURE; Name: sacral colpopexy; Assigned to Arm(s): N/A
D: Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Procedure: robotic laparoscopic sacrocolpopexy | Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Laparoscopic Sacral Colpopexy | Intervention Type: PROCEDURE; Name: robotic laparoscopic sacrocolpopexy; Assigned to Arm(s): 2 | Intervention Type: PROCEDURE; Name: Laparoscopic Sacral Colpopexy; Assigned to Arm(s): 1

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: CARE: A Randomized Trial of Colpopexy and Urinary Reduction Efforts
Brief Summary: Pelvic organ prolapse occurs when the muscles holding pelvic organs (e.g., the uterus or bladder) weaken and the organs fall or slide down into the vagina. Pelvic organ prolapse can be corrected with surgery. However, women who have this surgery may develop urinary incontinence. This study will determine how doctors can predict this problem and whether an additional surgical procedure at the time of prolapse surgery can prevent the development of urinary incontinence.


Options:
A: Arm Label: Abdominal Sacral Colpopexy with no Burch colposuspension; Type: N/A; Interventions: N/A | Arm Label: Abdominal Sacral Colpopexy with Burch Colposuspension; Type: N/A; Interventions: N/A
B: Arm Label: Abdominal Sacral Colpopexy with no Burch colposuspension; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Abdominal Sacral Colpopexy with Burch Colposuspension; Type: EXPERIMENTAL; Interventions: Procedure: Burch urethropexy at time of sacrocolpopexy | Intervention Type: PROCEDURE; Name: Burch urethropexy at time of sacrocolpopexy; Assigned to Arm(s): Abdominal Sacral Colpopexy with Burch Colposuspension
C: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Procedure: retropubic mid-urethral sling (TVT) | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Procedure: transobturator mid-urethral sling (TVT-O and the Monarc) | Intervention Type: PROCEDURE; Name: retropubic mid-urethral sling (TVT); Assigned to Arm(s): 1 | Intervention Type: PROCEDURE; Name: transobturator mid-urethral sling (TVT-O and the Monarc); Assigned to Arm(s): 2
D: Arm Label: Burch; Type: OTHER; Interventions: Procedure: Burch Modified Tanagho | Arm Label: Sling; Type: OTHER; Interventions: Procedure: Autologous Fascia Sling | Intervention Type: PROCEDURE; Name: Burch Modified Tanagho; Assigned to Arm(s): Burch | Intervention Type: PROCEDURE; Name: Autologous Fascia Sling; Assigned to Arm(s): Sling

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Joint Attention Intervention With Caregivers and Their Children With Autism
Brief Summary: Toddlers with autism have poor joint attention skills. Joint attention skills include pointing to objects, following another person's gaze, and responding to invitations to join in a social interaction. Improved joint attention skills may lead to better verbal ability as the child ages. This study teaches caregivers how to help their toddlers with autism develop joint attention skills.


Options:
A: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Intensive behavioral therapy | Arm Label: 2; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Intensive behavioral therapy; Assigned to Arm(s): 1
B: Intervention Type: BEHAVIORAL; Name: Caregiver joint attention intervention; Assigned to Arm(s): N/A
C: Intervention Type: BEHAVIORAL; Name: Joint attention intervention; Assigned to Arm(s): N/A
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Social skills training targeting children with autism | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Behavioral: Social skills training of peers without autism | Arm Label: 3; Type: EXPERIMENTAL; Interventions: Behavioral: Combination treatment of social skills/education about autism | Arm Label: 4; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Usual training | Intervention Type: BEHAVIORAL; Name: Social skills training targeting children with autism; Assigned to Arm(s): 1 | Intervention Type: BEHAVIORAL; Name: Social skills training of peers without autism; Assigned to Arm(s): 2 | Intervention Type: BEHAVIORAL; Name: Combination treatment of social skills/education about autism; Assigned to Arm(s): 3 | Intervention Type: BEHAVIORAL; Name: Usual training; Assigned to Arm(s): 4

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Joint Attention Intervention With Caregivers and Their Children With Autism
Brief Summary: Toddlers with autism have poor joint attention skills. Joint attention skills include pointing to objects, following another person's gaze, and responding to invitations to join in a social interaction. Improved joint attention skills may lead to better verbal ability as the child ages. This study teaches caregivers how to help their toddlers with autism develop joint attention skills.


Options:
A: Intervention Type: BEHAVIORAL; Name: Joint attention intervention; Assigned to Arm(s): N/A
B: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Early intervention blending several tx approaches, w/ focus | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Early intervention blending several treatment approaches | Intervention Type: BEHAVIORAL; Name: Early intervention blending several tx approaches, w/ focus; Assigned to Arm(s): 1 | Intervention Type: BEHAVIORAL; Name: Early intervention blending several treatment approaches; Assigned to Arm(s): 2
C: Intervention Type: BEHAVIORAL; Name: Caregiver joint attention intervention; Assigned to Arm(s): N/A
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Intensive behavioral therapy | Arm Label: 2; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Intensive behavioral therapy; Assigned to Arm(s): 1

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multisite Controlled Secretin Trial in Autism
Brief Summary: Many drugs used to treat autism target specific symptoms, such as hyperactivity and aggressiveness. Few drugs target the core autistic symptoms of impaired social interaction and communication. This study will evaluate two forms of the drug secretin for the treatment of core autistic symptoms.


Options:
A: Arm Label: Lurasidone 20 mg; Type: EXPERIMENTAL; Interventions: Drug: Lurasidone 20 mg daily | Arm Label: Lurasidone 60 mg; Type: EXPERIMENTAL; Interventions: Drug: Lurasidone | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Lurasidone 20 mg daily; Assigned to Arm(s): Lurasidone 20 mg | Intervention Type: DRUG; Name: Lurasidone; Assigned to Arm(s): Lurasidone 60 mg | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
B: Intervention Type: DRUG; Name: secretin, synthetic porcine; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: secretin, biologically derived porcine; Assigned to Arm(s): N/A
C: Arm Label: sapropterin, 100 mg capsules; Type: EXPERIMENTAL; Interventions: Drug: sapropterin | Arm Label: Placebo, matching active drug; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: sapropterin; Assigned to Arm(s): sapropterin, 100 mg capsules | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo, matching active drug
D: Intervention Type: DRUG; Name: Risperidone; Assigned to Arm(s): N/A

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multisite Controlled Secretin Trial in Autism
Brief Summary: Many drugs used to treat autism target specific symptoms, such as hyperactivity and aggressiveness. Few drugs target the core autistic symptoms of impaired social interaction and communication. This study will evaluate two forms of the drug secretin for the treatment of core autistic symptoms.


Options:
A: Arm Label: Memantine; Type: EXPERIMENTAL; Interventions: Drug: Memantine | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: Memantine; Assigned to Arm(s): Memantine | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Placebo
B: Intervention Type: DRUG; Name: Intramuscular Olanzepine 10 mg; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Intramuscular Haloperidol 5-10 mg + Promethazine 25-50 mg; Assigned to Arm(s): N/A
C: Intervention Type: DRUG; Name: secretin, synthetic porcine; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: secretin, biologically derived porcine; Assigned to Arm(s): N/A
D: Arm Label: Aripiprazole; Type: EXPERIMENTAL; Interventions: Drug: Aripiprazole | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebos | Intervention Type: DRUG; Name: Aripiprazole; Assigned to Arm(s): Aripiprazole | Intervention Type: DRUG; Name: Placebos; Assigned to Arm(s): Placebo

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multisite Controlled Secretin Trial in Autism
Brief Summary: Many drugs used to treat autism target specific symptoms, such as hyperactivity and aggressiveness. Few drugs target the core autistic symptoms of impaired social interaction and communication. This study will evaluate two forms of the drug secretin for the treatment of core autistic symptoms.


Options:
A: Arm Label: Placebo for AChEI and Choline; Type: PLACEBO_COMPARATOR; Interventions: Drug: Indistinguishable placebo tablets, matching both donepezil and choline | Arm Label: AChEI and Choline; Type: EXPERIMENTAL; Interventions: Drug: Acetyl-Choline Esterase Inhibitors and Choline supplements | Intervention Type: DRUG; Name: Acetyl-Choline Esterase Inhibitors and Choline supplements; Assigned to Arm(s): AChEI and Choline | Intervention Type: DRUG; Name: Indistinguishable placebo tablets, matching both donepezil and choline; Assigned to Arm(s): Placebo for AChEI and Choline
B: Intervention Type: DRUG; Name: secretin, synthetic porcine; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: secretin, biologically derived porcine; Assigned to Arm(s): N/A
C: Arm Label: Arbaclofen; Type: ACTIVE_COMPARATOR; Interventions: Drug: Arbaclofen | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Intervention Type: DRUG; Name: Arbaclofen; Assigned to Arm(s): Arbaclofen | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Placebo
D: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: Divalproex Sodium; Type: EXPERIMENTAL; Interventions: Drug: Divalproex sodium | Intervention Type: DRUG; Name: Divalproex sodium; Assigned to Arm(s): Divalproex Sodium | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Low-Dose Doxycycline Effects on Osteopenic Bone Loss
Brief Summary: The primary purpose of this clinical trial is to determine whether low-dose doxycycline can reduce alveolar bone density loss in postmenopausal osteopenic women with periodontitis and not on hormone replacement therapy (i.e., estrogen deficient).


Options:
A: Intervention Type: BEHAVIORAL; Name: Nutritional and life style counseling; Assigned to Arm(s): N/A
B: Arm Label: low-dose doxycycline; Type: EXPERIMENTAL; Interventions: Drug: 20 mg doxycycline hyclate | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: 20 mg doxycycline hyclate; Assigned to Arm(s): low-dose doxycycline | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
C: Arm Label: Comprehensive treatment; Type: EXPERIMENTAL; Interventions: Device: Subgingival scaling and root planing | Arm Label: Community treatment; Type: OTHER; Interventions: Device: Oral prophylaxis | Intervention Type: DEVICE; Name: Subgingival scaling and root planing; Assigned to Arm(s): Comprehensive treatment | Intervention Type: DEVICE; Name: Oral prophylaxis; Assigned to Arm(s): Community treatment
D: Arm Label: One-Stage Full-Mouth Disinfection; Type: EXPERIMENTAL; Interventions: Procedure: One-Stage Full-Mouth Disinfection | Arm Label: Periodontal care; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Periodontal care | Intervention Type: PROCEDURE; Name: One-Stage Full-Mouth Disinfection; Assigned to Arm(s): One-Stage Full-Mouth Disinfection | Intervention Type: PROCEDURE; Name: Periodontal care; Assigned to Arm(s): Periodontal care

Answer: B