TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Prophylactic Pregabalin to Decrease Pain During Medical Abortion: a Randomized Controlled Trial
Brief Summary: Medical abortion has been associated with significant pain. The objective of this trial is to determine whether one dose of pregabalin 300 mg, given during medical abortion in addition to the standard of care analgesics, will decrease experienced pain. Investigators will perform a randomized, double-blinded, placebo-controlled trial. Participant pain levels and side effects will be assessed at multiple time points, along with a measure of satisfaction.


Options:
A: Arm Label: Pregabalin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Pregabalin | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Pregabalin; Assigned to Arm(s): Pregabalin | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
B: Arm Label: Mifepristone at home 24 hours before miso dosing starts; Type: EXPERIMENTAL; Interventions: Drug: Mifepristone | Arm Label: Mifepristone and first dose of misoprostol simultaneously.; Type: EXPERIMENTAL; Interventions: Drug: Misoprostol | Intervention Type: DRUG; Name: Mifepristone; Assigned to Arm(s): Mifepristone at home 24 hours before miso dosing starts | Intervention Type: DRUG; Name: Misoprostol; Assigned to Arm(s): Mifepristone and first dose of misoprostol simultaneously.
C: Arm Label: Therapeutic; Type: ACTIVE_COMPARATOR; Interventions: Drug: Ibuprofen | Arm Label: Prophylactic; Type: ACTIVE_COMPARATOR; Interventions: Drug: Ibuprofen | Intervention Type: DRUG; Name: Ibuprofen; Assigned to Arm(s): Prophylactic, Therapeutic
D: Arm Label: ibuprofen; Type: EXPERIMENTAL; Interventions: Drug: ibuprofen | Arm Label: placebo; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: ibuprofen; Assigned to Arm(s): ibuprofen

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase 3 Randomized, Multicenter, Multinational, Double-blinded Study Comparing the Efficacy and Safety of Repeated Biweekly Infusions of Avalglucosidase Alfa (neoGAA, GZ402666) and Alglucosidase Alfa in Treatment naïve Patients With Late-onset Pompe Disease
Brief Summary: Primary Objective:

To determine the effect of avalglucosidase alfa treatment on respiratory muscle strength measured by percent (%) predicted forced vital capacity (FVC) in the upright position, as compared to alglucosidase alfa.

Secondary Objective:

To determine the safety and effect of avalglucosidase alfa treatment on functional endurance (6-minute walk test, inspiratory muscle strength (maximum inspiratory pressure), expiratory muscle strength (maximum expiratory pressure), lower extremity muscle strength (hand-held dynamometry), motor function (Quick Motor Function Test), and health-related quality of life (Short Form-12).


Options:
A: Arm Label: Clenbuterol; Type: EXPERIMENTAL; Interventions: Drug: Clenbuterol | Arm Label: Placebo Comparator; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Clenbuterol; Assigned to Arm(s): Clenbuterol | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo Comparator
B: Arm Label: avalglucosidase alfa (GZ402666); Type: EXPERIMENTAL; Interventions: Drug: Avalglucosidase alfa (GZ402666) | Arm Label: alglucosidase alfa (GZ419829); Type: ACTIVE_COMPARATOR; Interventions: Drug: Alglucosidase alfa (GZ419829) | Intervention Type: DRUG; Name: Avalglucosidase alfa (GZ402666); Assigned to Arm(s): avalglucosidase alfa (GZ402666) | Intervention Type: DRUG; Name: Alglucosidase alfa (GZ419829); Assigned to Arm(s): alglucosidase alfa (GZ419829)
C: Arm Label: alglucosidase alfa; Type: ACTIVE_COMPARATOR; Interventions: Biological: alglucosidase alfa | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: BIOLOGICAL; Name: alglucosidase alfa; Assigned to Arm(s): alglucosidase alfa | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
D: Arm Label: Alglucosidase Alfa/Alglucosidase Alfa; Type: EXPERIMENTAL; Interventions: Biological: alglucosidase alfa | Arm Label: Placebo/Alglucosidase Alfa; Type: EXPERIMENTAL; Interventions: Biological: alglucosidase alfa | Intervention Type: BIOLOGICAL; Name: alglucosidase alfa; Assigned to Arm(s): Alglucosidase Alfa/Alglucosidase Alfa, Placebo/Alglucosidase Alfa

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Impact of Text Messaging on Medication Adherence and Exercise Regimen Among Post-myocardial Infarction Patients
Brief Summary: The purpose of this study is to assess the impact of text message reminders on adherence to medications and exercise in patients recently discharged from the hospital after a myocardial infarction (MI).


Options:
A: Arm Label: Medication text message; Type: EXPERIMENTAL; Interventions: Behavioral: Text message reminder for medication adherence | Arm Label: Exercise text message; Type: EXPERIMENTAL; Interventions: Behavioral: Text message reminder for exercise regimen | Arm Label: Usual care, medication adherence; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Usual care, exercise regimen; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Text message reminder for medication adherence; Assigned to Arm(s): Medication text message | Intervention Type: BEHAVIORAL; Name: Text message reminder for exercise regimen; Assigned to Arm(s): Exercise text message
B: Arm Label: Center-based cardiac rehabilitation; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Center-based cardiac rehabilitation | Arm Label: Home-based training with telemonitoring guidance; Type: EXPERIMENTAL; Interventions: Behavioral: Home-based training with telemonitoring guidance | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Center-based cardiac rehabilitation; Assigned to Arm(s): Center-based cardiac rehabilitation | Intervention Type: BEHAVIORAL; Name: Home-based training with telemonitoring guidance; Assigned to Arm(s): Home-based training with telemonitoring guidance
C: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Rehabilitation in institution | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Rehabilitation at home, Behavioral: Out-patient rehabilitation at the hospital | Intervention Type: BEHAVIORAL; Name: Rehabilitation in institution; Assigned to Arm(s): 1 | Intervention Type: BEHAVIORAL; Name: Rehabilitation at home; Assigned to Arm(s): 2 | Intervention Type: BEHAVIORAL; Name: Out-patient rehabilitation at the hospital; Assigned to Arm(s): 2
D: Arm Label: Telerehabilitation group; Type: EXPERIMENTAL; Interventions: Other: Telerehabilitation group | Arm Label: Centre - based rehabilitation group; Type: ACTIVE_COMPARATOR; Interventions: Other: Centre - based rehabilitation group | Arm Label: Usual care group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Telerehabilitation group; Assigned to Arm(s): Telerehabilitation group | Intervention Type: OTHER; Name: Centre - based rehabilitation group; Assigned to Arm(s): Centre - based rehabilitation group

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Impact of Text Messaging on Medication Adherence and Exercise Regimen Among Post-myocardial Infarction Patients
Brief Summary: The purpose of this study is to assess the impact of text message reminders on adherence to medications and exercise in patients recently discharged from the hospital after a myocardial infarction (MI).


Options:
A: Arm Label: SMS Short Message Service Arm plus Prescription; Type: EXPERIMENTAL; Interventions: Behavioral: SMS- Short Messaging Service | Arm Label: Standard Prescriptions and Counselling; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: SMS- Short Messaging Service; Assigned to Arm(s): SMS Short Message Service Arm plus Prescription
B: Arm Label: Intervention SMS; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Intervention SMS | Arm Label: Control SMS; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Control SMS | Intervention Type: BEHAVIORAL; Name: Intervention SMS; Assigned to Arm(s): Intervention SMS | Intervention Type: BEHAVIORAL; Name: Control SMS; Assigned to Arm(s): Control SMS
C: Arm Label: Experimental; Type: EXPERIMENTAL; Interventions: Behavioral: Mobile phone text message | Arm Label: No Intervention; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Mobile phone text message; Assigned to Arm(s): Experimental
D: Arm Label: Medication text message; Type: EXPERIMENTAL; Interventions: Behavioral: Text message reminder for medication adherence | Arm Label: Exercise text message; Type: EXPERIMENTAL; Interventions: Behavioral: Text message reminder for exercise regimen | Arm Label: Usual care, medication adherence; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Usual care, exercise regimen; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Text message reminder for medication adherence; Assigned to Arm(s): Medication text message | Intervention Type: BEHAVIORAL; Name: Text message reminder for exercise regimen; Assigned to Arm(s): Exercise text message

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multicentre Controlled, Randomized Clinical Trial to Compare the Efficacy and Safety of Ambulatory Treatment of Mild Acute Diverticulitis Without Antibiotics With the Standard Treatment With Antibiotics
Brief Summary: Patients with mild acute diverticulitis (modified Neff 0 grade), following the inclusion criteria and giving informed consent, will be included in the study protocol and will be randomly assigned to one of the treatment arms: symptomatic treatment with NSAID plus antibiotic vs symptomatic treatment with NSAID only. They will be followed-up at 48 hours, 7 days, 30 days and 3 months from the onset of the episode.


Options:
A: Arm Label: Symptomatic treatment with NSAID; Type: EXPERIMENTAL; Interventions: Drug: Ibuprofen, Drug: Acetaminophen | Arm Label: Antibiotic+symptomatic treatment with NSAID; Type: ACTIVE_COMPARATOR; Interventions: Drug: Ibuprofen, Drug: Acetaminophen, Drug: Amoxicillin/clavulanic acid | Intervention Type: DRUG; Name: Ibuprofen; Assigned to Arm(s): Antibiotic+symptomatic treatment with NSAID, Symptomatic treatment with NSAID | Intervention Type: DRUG; Name: Acetaminophen; Assigned to Arm(s): Antibiotic+symptomatic treatment with NSAID, Symptomatic treatment with NSAID | Intervention Type: DRUG; Name: Amoxicillin/clavulanic acid; Assigned to Arm(s): Antibiotic+symptomatic treatment with NSAID
B: Arm Label: Antibiotic; Type: ACTIVE_COMPARATOR; Interventions: Drug: Antibiotic | Arm Label: No antibiotic; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: Antibiotic; Assigned to Arm(s): Antibiotic
C: Arm Label: Conservative strategy with antibiotics; Type: ACTIVE_COMPARATOR; Interventions: Drug: Amoxicillin-clavulanate | Arm Label: Liberal strategy without antibiotics; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: Amoxicillin-clavulanate; Assigned to Arm(s): Conservative strategy with antibiotics
D: Arm Label: Cephalosporin + Metronidazole; Type: ACTIVE_COMPARATOR; Interventions: Drug: Cephalosporin + Metronidazole | Arm Label: No antibiotic; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: Cephalosporin + Metronidazole; Assigned to Arm(s): Cephalosporin + Metronidazole

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Integrated Primary Care for Chronic Lung Diseases in Less Developed Countries: Pragmatic Trial of the Practical Approach to Care Kit in Brazil (PACK Brazil)
Brief Summary: This study will evaluate a complex intervention based on a patient management tool (PMT), combined with educational outreach to primary care doctors, nurses and other health workers, in the Brazilian city of Florianopolis. The intervention is aimed at improving the quality of respiratory care and respiratory health outcomes, and comorbid conditions, in adults with asthma and chronic obstructive pulmonary disease (COPD). The effectiveness of the intervention will be assessed by randomly allocating 48 primary care clinics to receive the intervention or not, and comparing patient and clinic level endpoints that reflect the health and quality of care provided over the following year. About 1250 patients known to have been diagnosed with asthma and 700 with COPD in participating clinics and will be included in the study. The primary endpoints for patients with asthma and COPD, respectively, will be composite scores indicating appropriate prescribing and diagnostic testing. The third primary endpoint, among all adult clinic users, will be rates of new diagnoses of asthma and COPD in each clinic. Secondary endpoints will include the individual components of the composite scores, health measures (hospital admissions and deaths), and indicators of appropriate management of comorbid conditions such as cardiovascular risk factors. Eligible patients will be identified and outcomes measured using electronic medical records.


Options:
A: Arm Label: Usual information policy; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Antibiotic therapy guidelines; Type: OTHER; Interventions: Other: Mailing of antibiotic therapy guidelines to the sentinel physicians | Intervention Type: OTHER; Name: Mailing of antibiotic therapy guidelines to the sentinel physicians; Assigned to Arm(s): Antibiotic therapy guidelines
B: Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Outreach education training | Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: No outreach education training | Intervention Type: BEHAVIORAL; Name: Outreach education training; Assigned to Arm(s): Intervention | Intervention Type: BEHAVIORAL; Name: No outreach education training; Assigned to Arm(s): Control
C: Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Outreach education training | Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: No outreach education training | Intervention Type: BEHAVIORAL; Name: Outreach education training; Assigned to Arm(s): Intervention | Intervention Type: BEHAVIORAL; Name: No outreach education training; Assigned to Arm(s): Control
D: Arm Label: A; Type: EXPERIMENTAL; Interventions: Device: half-yearly monitoring routine | Arm Label: B; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: half-yearly monitoring routine; Assigned to Arm(s): A

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: REACH Lifestyle Program for Older Adults
Brief Summary: The purpose of this study is to test feasibility for the delivery and perceptions of a lifestyle model for middle-aged and older adults by involving participants in its development. The goal of the program is to reduce sedentary behaviour, increase physical activity, and increase strength and balance. An optional walking program will be run in parallel to emphasize the importance of moving more. Participants will be asked to fill out questionnaires on course delivery, content and effect throughout the program and 2-3 recorded interviews throughout the study. We will collect measurements of physical performance before and after the program.


Options:
A: Arm Label: Sedentary behaviour reduction (behaviour change techniques); Type: EXPERIMENTAL; Interventions: Behavioral: Sedentary behaviour reduction using motivational interviewing, education, individualised feedback, goal-setting, self-monitoring, environmental modification, and supportive phone calls | Arm Label: Usual care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Sedentary behaviour reduction using motivational interviewing, education, individualised feedback, goal-setting, self-monitoring, environmental modification, and supportive phone calls; Assigned to Arm(s): Sedentary behaviour reduction (behaviour change techniques)
B: Arm Label: REACH Participant Course; Type: EXPERIMENTAL; Interventions: Behavioral: REACH | Intervention Type: BEHAVIORAL; Name: REACH; Assigned to Arm(s): REACH Participant Course
C: Arm Label: Intervention group; Type: EXPERIMENTAL; Interventions: Behavioral: MyPlan 2.0 | Arm Label: Waiting-list control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: MyPlan 2.0; Assigned to Arm(s): Intervention group
D: Arm Label: Exercise programme only; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: SMS reminder; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise programme plus SMS reminders | Intervention Type: BEHAVIORAL; Name: Exercise programme plus SMS reminders; Assigned to Arm(s): SMS reminder

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Carbohydrate-restricted Diet to Reverse Fatty Liver in Adolescents With Obesity
Brief Summary: The purpose of this study is to determine the effects of a low carbohydrate diet vs a low fat diet on improvement in aminotransferases, hepatic fat infiltration, markers of inflammation, insulin resistance, and body composition in obese adolescents with non-alcoholic fatty liver disease (NAFLD).


Options:
A: Arm Label: Lifestyle counseling; Type: OTHER; Interventions: Other: multidisciplinary intervention | Intervention Type: OTHER; Name: multidisciplinary intervention; Assigned to Arm(s): Lifestyle counseling
B: Arm Label: Intensive exercise; Type: EXPERIMENTAL; Interventions: Other: Intensive exercise | Arm Label: Lifestyle counseling; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Regular exercise; Type: EXPERIMENTAL; Interventions: Other: Conventional exercise | Intervention Type: OTHER; Name: Intensive exercise; Assigned to Arm(s): Intensive exercise | Intervention Type: OTHER; Name: Conventional exercise; Assigned to Arm(s): Regular exercise
C: Arm Label: Carbohydrate-restricted diet; Type: EXPERIMENTAL; Interventions: Other: Carbohydrate-restricted diet | Arm Label: Control, low-fat diet; Type: ACTIVE_COMPARATOR; Interventions: Other: Control, low-fat diet | Intervention Type: OTHER; Name: Carbohydrate-restricted diet; Assigned to Arm(s): Carbohydrate-restricted diet | Intervention Type: OTHER; Name: Control, low-fat diet; Assigned to Arm(s): Control, low-fat diet
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Low glycemic load diet | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Low fat diet | Intervention Type: BEHAVIORAL; Name: Low glycemic load diet; Assigned to Arm(s): 1 | Intervention Type: BEHAVIORAL; Name: Low fat diet; Assigned to Arm(s): 2

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Pharmacist-delivered Multifaceted Intervention to Enhance Medication Adherence Among Post-acute Coronary Syndrome Patients in Vietnam: A Randomised Controlled Trial
Brief Summary: Adherence to treatment in post-acute coronary syndrome patients has been found to be poor in several studies. Pharmacists play a significant role in enhancing medication adherence and reducing rates of mortality and re-admission to hospital by performing medication reconciliation and tailoring, and patient education. The purpose of this study is to determine the effect of pharmacist-delivered multifaceted intervention on medication adherence and clinical outcomes of post-acute coronary syndrome patients. The study will be designed as a randomised controlled trial with blinded outcome assessors. The population includes patients who survive during hospitalisation with discharge diagnosis of acute coronary syndrome. Pharmacist-delivered multifaceted intervention consists of two counselling sessions within 1 week before and after hospital discharge including medication reconciliation and tailoring, and support with pill organiser and drug information leaflet. Primary outcome measure is the proportion of patients adherent to medication at 1 month after discharge. Secondary outcome measures are the proportions of patients (1) adherent to medication at 3 months after discharge, (2) readmitted to hospital and (3) dying within 3 months after discharge. The investigators also measure (4) the change in quality of life and (5) beliefs about medicines from baseline at 3 months.


Options:
A: Arm Label: Intervention group; Type: EXPERIMENTAL; Interventions: Behavioral: Pharmacist-delivered multifaceted intervention | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Pharmacist-delivered multifaceted intervention; Assigned to Arm(s): Intervention group
B: Arm Label: Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: C-TraIn; Type: EXPERIMENTAL; Interventions: Other: Care Transitions Innovation (C-TraIn) | Intervention Type: OTHER; Name: Care Transitions Innovation (C-TraIn); Assigned to Arm(s): C-TraIn
C: Arm Label: MI + IVR; Type: EXPERIMENTAL; Interventions: Behavioral: MI + IVR | Arm Label: Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: MI + IVR; Assigned to Arm(s): MI + IVR
D: Arm Label: Minimal intervention; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Minimal intervention | Arm Label: Enhanced intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Enhanced Intervention | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Minimal intervention; Assigned to Arm(s): Minimal intervention | Intervention Type: BEHAVIORAL; Name: Enhanced Intervention; Assigned to Arm(s): Enhanced intervention

Answer: A