Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: An RCT to Determine if APBI, Utilizing 3D CRT, is as Effective as Whole Breast Irradiation Following Breast Conserving Surgery in Women With Ductal Carcinoma in Situ or Invasive Breast Cancer With Negative Axillary Lymph Nodes
Brief Summary: To determine if Accelerated Partial Breast Irradiation, using 3D CRT, is as effective as Whole Breast Irradiation following breast conserving surgery in women with an new histological diagnosis of ductal carcinoma in situ only or invasive breast cancer without evidence of metastatic disease. Effectiveness will be determined by the rate of ipsilateral breast tumour recurrence.

General objective is to improve the convenience and quality of life of female patients who receive breast irradiation.


Options:
A: Arm Label: APBI utilizing 3D-CRT radiation; Type: EXPERIMENTAL; Interventions: Radiation: APBI utilizing 3D-CRT radiation | Arm Label: Whole breast irradiation; Type: OTHER; Interventions: Radiation: Whole breast irradiation | Intervention Type: RADIATION; Name: APBI utilizing 3D-CRT radiation; Assigned to Arm(s): APBI utilizing 3D-CRT radiation | Intervention Type: RADIATION; Name: Whole breast irradiation; Assigned to Arm(s): Whole breast irradiation
B: Arm Label: Whole breast irradiation (WBI); Type: ACTIVE_COMPARATOR; Interventions: Radiation: Whole breast irradiation (WBI) | Arm Label: Partial breast irradiation (APBI); Type: EXPERIMENTAL; Interventions: Radiation: Accelerated partial breast irradiation (APBI) | Intervention Type: RADIATION; Name: Accelerated partial breast irradiation (APBI); Assigned to Arm(s): Partial breast irradiation (APBI) | Intervention Type: RADIATION; Name: Whole breast irradiation (WBI); Assigned to Arm(s): Whole breast irradiation (WBI)
C: Arm Label: Group 1: WBI; Type: ACTIVE_COMPARATOR; Interventions: Radiation: whole breast irradiation | Arm Label: Group 2: PBI; Type: EXPERIMENTAL; Interventions: Radiation: 3-dimensional conformal accelerated partial breast irradiation, Radiation: brachytherapy, Radiation: MammoSite or other single-entry intracavitary device | Intervention Type: RADIATION; Name: 3-dimensional conformal accelerated partial breast irradiation; Assigned to Arm(s): Group 2: PBI | Intervention Type: RADIATION; Name: brachytherapy; Assigned to Arm(s): Group 2: PBI | Intervention Type: RADIATION; Name: whole breast irradiation; Assigned to Arm(s): Group 1: WBI | Intervention Type: RADIATION; Name: MammoSite or other single-entry intracavitary device; Assigned to Arm(s): Group 2: PBI
D: Arm Label: Standard or Hypofractionated radiotherapy; Type: ACTIVE_COMPARATOR; Interventions: Radiation: Whole Breast Irradiation + Boost or Hypofractionated irradiation | Arm Label: Accelerated Partial Breast Irradiation (APBI); Type: EXPERIMENTAL; Interventions: Radiation: Accelerated partial breast irradiation | Intervention Type: RADIATION; Name: Whole Breast Irradiation + Boost or Hypofractionated irradiation; Assigned to Arm(s): Standard or Hypofractionated radiotherapy | Intervention Type: RADIATION; Name: Accelerated partial breast irradiation; Assigned to Arm(s): Accelerated Partial Breast Irradiation (APBI)

Answer: A