Please select the outcome measures that correspond to the clinical trial below.
Title: Pomegranate Supplementation Accelerates the Recovery Kinetics of Muscle Damage, Muscle Soreness and Inflammatory Marker After Weightlifting Training Session.
Brief Summary: From the recent scientific literature in the field of biological response to physical exercise, a significant increase in muscle damage, soreness and inflammation were registered immediately and even 48 after resistance exercise. In the other hand, from the recent scientific literature in the field of nutrition it is well established that Pomegranate juice is a potent antioxidant that can help prevent or treat various disease risk factors. However, only few studies associated the effect of the pomegranate with the physical exercise. To the authors' knowledge, there are no studies investigated the acute and delayed effect of pomegranate supplementation in performance and muscle recovery after exercises involved muscle of whole body. Therefore, the aim of the present study was to investigate the effect of natural Pomegranate juice supplementation on the acute and delayed response of muscle soreness and biochemical parameters following weightlifting training session


Options:
A: PGC-1alpha mRNA expression in skeletal muscle PPARgamma mRNA expression in skeletal muscle Serum malondialdehyde concentration (after 4 weeks)
B: Change in physical performance from using Placebo to using Pomegranate juice (3min after Placebo and Pomegranate training sessions); Change in Acute Hematological responses from using Placebo to using Pomegranate juice (3min after Placebo and Pomegranate training sessions); Change in Acute Biochemical responses from using Placebo to using Pomegranate juice (3min after Placebo and Pomegranate training sessions); Change in Delayed Hematological responses from using Placebo to using Pomegranate juice (48h after Placebo and Pomegranate training sessions); Change in Delayed Biochemical responses from using Placebo to using Pomegranate juice (48h after Placebo and Pomegranate training sessions)
C: Change in reduced glutathione in blood (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in reduced glutathione in muscle (one hour before exercise, 2 hours post-exercise, 2 days post-exercise, 8 days post-exercise); Change in protein carbonyls in red blood cells and serum (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in protein carbonyls in muscle (one hour before exercise, 2 hours post-exercise, 2 days post-exercise, 8 days post-exercise); Change in thiobarbituric acid reactive substances in red blood cells and serum (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in thiobarbituric acid reactive substances in muscle (one hour before exercise, 2 hours post-exercise, 2 days post-exercise, 8 days post-exercise); Change in oxidized glutathione in red blood cells and blood (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in total antioxidant capacity in serum (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in oxidized glutathione in muscle (one hour before exercise, 2 hours post-exercise, 2 days post-exercise, 8 days post-exercise); Change in catalase activity in red blood cells and serum (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in glutathione peroxidase activity in red blood cells (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in creatine kinase activity in plasma (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in C-reactive protein in plasma (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in macrophage infiltration in muscle (one hour before exercise, 2 hours post-exercise, 2 days post-exercise, 8 days post-exercise); Change in white blood cell count in blood (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in neutrophil count in blood (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in fatty acid binding protein in plasma (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in cortisol concentration in blood (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in testosterone concentration in plasma (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in cytokine concentration in plasma (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in adhesion molecule concentration in blood (one hour before exercise, 5 minutes post-exercise, 2 hours post-exercise, daily for 8 days post-exercise); Change in intracellular signalling proteins in muscle (one hour before exercise, 2 hours post-exercise, 2 days post-exercise, 8 days post-exercise); Change in myogenic determination factor (MyoD) protein levels in muscle (one hour before exercise, 2 hours post-exercise, 2 days post-exercise, 8 days post-exercise); Change in tumor necrosis factor α in muscle (one hour before exercise, 2 hours post-exercise, 2 days post-exercise, 8 days post-exercise)
D: Improvement of muscle effort tolerance after antioxidant supplementation (duration study 3 years)

Answer: B