Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effective Aids Treatment and Support in the Free State (FEATS): Adherence and Nutritional Support for Effective and Sustainable Antiretroviral Treatment in Resource Constrained Settings
Brief Summary: The aim of this study is to investigate the benefits of ARV treatment to patients, to the family members of patients on ARV treatment, and to communities at large. The study also aims to investigate the impact of a peer adherence support and a nutritional intervention on measures of treatment success. To this end, 648 patients who had commenced ARV treatment in the past month at twelve selected health care facilities will be recruited into the study. In addition, 204 randomly sampled households from the communities served by the twelve selected clinics will be recruited into the study. Trained enumerators will at baseline conduct semi-structured interviews with patients and households. Following the baseline survey, patients recruited into the study will be randomly assigned to one of three groups:

* Patients receiving ARV treatment and the associated support currently provided in the public sector ARV treatment programme.
* Patients receiving (a) plus bi-weekly visits by an experienced ARV patient who has been trained as a peer adherence supporter
* Patients receiving (a) and (b) plus a weekly nutritional supplement in the form of two 400g cans of meatballs and spaghetti in tomato sauce The group of 'comparison' households comprises the fourth group. Trained enumerators will conduct follow-up interviews with all patients and households at approximately six- and at twelve-months respectively. In addition, the ARV coordinator and other providers working in the ARV treatment programme at each of the twelve selected health care facilities will be interviewed by trained enumerators, at baseline and again at six- and at twelve-months. Clinical data will be obtained from patient files at baseline and at completion of the study. Using these data, various outcomes of importance to the study will be compared between the four study groups, using experimental and non-experimental methods.


Options:
A: Arm Label: Step-by-Step; Type: EXPERIMENTAL; Interventions: Behavioral: Step-by-Step | Arm Label: Enhanced care as usual; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Enhanced care as usual | Intervention Type: BEHAVIORAL; Name: Step-by-Step; Assigned to Arm(s): Step-by-Step | Intervention Type: BEHAVIORAL; Name: Enhanced care as usual; Assigned to Arm(s): Enhanced care as usual
B: Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Psychosocial support training for school teachers | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Psychosocial support training for school teachers; Assigned to Arm(s): Intervention
C: Arm Label: Livestock microfinance; Type: EXPERIMENTAL; Interventions: Behavioral: Livestock Microfinance | Arm Label: Delayed Control Group; Type: ACTIVE_COMPARATOR; Interventions: Other: Delayed Control Group | Intervention Type: BEHAVIORAL; Name: Livestock Microfinance; Assigned to Arm(s): Livestock microfinance | Intervention Type: OTHER; Name: Delayed Control Group; Assigned to Arm(s): Delayed Control Group
D: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Drug: ARV treatment | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: ARV peer adherence support (PAS), Drug: ARV treatment | Arm Label: 3; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: ARV peer adherence support (PAS), Dietary Supplement: Nutritional support, Drug: ARV treatment | Arm Label: 4; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: ARV peer adherence support (PAS); Assigned to Arm(s): 2, 3 | Intervention Type: DIETARY_SUPPLEMENT; Name: Nutritional support; Assigned to Arm(s): 3 | Intervention Type: DRUG; Name: ARV treatment; Assigned to Arm(s): 1, 2, 3

Answer: D