Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Exposure, Safety and Local Tolerance Study Comparing the Relative Bioavailability of Oral Methotrexate and the VIBEX™ MTX Device in Adult Subjects With Rheumatoid Arthritis
Brief Summary: Relative Bioavailability Comparison study


Options:
A: Arm Label: 10 mg Methotrexate (MTX); Type: EXPERIMENTAL; Interventions: Drug: MTX | Arm Label: 15 mg MTX; Type: EXPERIMENTAL; Interventions: Drug: MTX | Arm Label: 20 mg MTX; Type: EXPERIMENTAL; Interventions: Drug: MTX | Arm Label: 25 mg MTX; Type: EXPERIMENTAL; Interventions: Drug: MTX | Intervention Type: DRUG; Name: MTX; Assigned to Arm(s): 10 mg Methotrexate (MTX), 15 mg MTX, 20 mg MTX, 25 mg MTX
B: Arm Label: Arm 1; Type: ACTIVE_COMPARATOR; Interventions: Drug: Etanercept, Drug: methotrexate, Drug: Placebo, triple | Arm Label: Arm 2; Type: ACTIVE_COMPARATOR; Interventions: Drug: methotrexate, Drug: Sulfasalazine, Drug: Hydroxychloroquine, Drug: Placebo, etanercept | Intervention Type: DRUG; Name: Etanercept; Assigned to Arm(s): Arm 1 | Intervention Type: DRUG; Name: methotrexate; Assigned to Arm(s): Arm 1, Arm 2 | Intervention Type: DRUG; Name: Sulfasalazine; Assigned to Arm(s): Arm 2 | Intervention Type: DRUG; Name: Hydroxychloroquine; Assigned to Arm(s): Arm 2 | Intervention Type: DRUG; Name: Placebo, triple; Assigned to Arm(s): Arm 1 | Intervention Type: DRUG; Name: Placebo, etanercept; Assigned to Arm(s): Arm 2
C: Arm Label: Group 1: Placebo + Methotrexate; Type: EXPERIMENTAL; Interventions: Drug: Placebo injections, Drug: Methotrexate capsules, Biological: Golimumab 50 mg injections, Biological: Golimumab 100 mg injections | Arm Label: Group 2: Golimumab 100 mg + Placebo; Type: EXPERIMENTAL; Interventions: Drug: Placebo capsules, Drug: Methotrexate capsules, Biological: Golimumab 50 mg injections, Biological: Golimumab 100 mg injections | Arm Label: Group 3: Golimumab 50 mg + Methotrexate; Type: EXPERIMENTAL; Interventions: Drug: Methotrexate capsules, Biological: Golimumab 50 mg injections, Biological: Golimumab 100 mg injections | Arm Label: Group 4: Golimumab 100 mg + Methotrexate; Type: EXPERIMENTAL; Interventions: Drug: Methotrexate capsules, Biological: Golimumab 50 mg injections, Biological: Golimumab 100 mg injections | Intervention Type: DRUG; Name: Placebo injections; Assigned to Arm(s): Group 1: Placebo + Methotrexate | Intervention Type: DRUG; Name: Placebo capsules; Assigned to Arm(s): Group 2: Golimumab 100 mg + Placebo | Intervention Type: DRUG; Name: Methotrexate capsules; Assigned to Arm(s): Group 1: Placebo + Methotrexate, Group 2: Golimumab 100 mg + Placebo, Group 3: Golimumab 50 mg + Methotrexate, Group 4: Golimumab 100 mg + Methotrexate | Intervention Type: BIOLOGICAL; Name: Golimumab 50 mg injections; Assigned to Arm(s): Group 1: Placebo + Methotrexate, Group 2: Golimumab 100 mg + Placebo, Group 3: Golimumab 50 mg + Methotrexate, Group 4: Golimumab 100 mg + Methotrexate | Intervention Type: BIOLOGICAL; Name: Golimumab 100 mg injections; Assigned to Arm(s): Group 1: Placebo + Methotrexate, Group 2: Golimumab 100 mg + Placebo, Group 3: Golimumab 50 mg + Methotrexate, Group 4: Golimumab 100 mg + Methotrexate
D: Arm Label: Arm 1; Type: PLACEBO_COMPARATOR; Interventions: Drug: BMS-945429 Placebo, Biological: BMS-945429, Drug: Methotrexate, Drug: Adalimumab Placebo | Arm Label: Arm 2; Type: EXPERIMENTAL; Interventions: Biological: BMS-945429, Drug: Methotrexate, Drug: Adalimumab Placebo | Arm Label: Arm 3; Type: EXPERIMENTAL; Interventions: Biological: BMS-945429, Drug: Methotrexate, Drug: Adalimumab Placebo | Arm Label: Arm 4; Type: EXPERIMENTAL; Interventions: Biological: BMS-945429, Drug: Methotrexate, Drug: Adalimumab Placebo | Arm Label: Arm 5; Type: EXPERIMENTAL; Interventions: Biological: BMS-945429, Drug: Methotrexate Placebo, Drug: Methotrexate, Drug: Adalimumab Placebo | Arm Label: Arm 6; Type: EXPERIMENTAL; Interventions: Biological: BMS-945429, Drug: Methotrexate Placebo, Drug: Methotrexate, Drug: Adalimumab Placebo | Arm Label: Arm 7; Type: ACTIVE_COMPARATOR; Interventions: Drug: Methotrexate, Drug: Adalimumab | Intervention Type: DRUG; Name: BMS-945429 Placebo; Assigned to Arm(s): Arm 1 | Intervention Type: BIOLOGICAL; Name: BMS-945429; Assigned to Arm(s): Arm 4 | Intervention Type: BIOLOGICAL; Name: BMS-945429; Assigned to Arm(s): Arm 3, Arm 6 | Intervention Type: BIOLOGICAL; Name: BMS-945429; Assigned to Arm(s): Arm 1, Arm 4 | Intervention Type: BIOLOGICAL; Name: BMS-945429; Assigned to Arm(s): Arm 2, Arm 5 | Intervention Type: DRUG; Name: Methotrexate; Assigned to Arm(s): Arm 1 | Intervention Type: DRUG; Name: Methotrexate; Assigned to Arm(s): Arm 2, Arm 3, Arm 4, Arm 7 | Intervention Type: DRUG; Name: Methotrexate Placebo; Assigned to Arm(s): Arm 5, Arm 6 | Intervention Type: DRUG; Name: Methotrexate; Assigned to Arm(s): Arm 5, Arm 6 | Intervention Type: DRUG; Name: Adalimumab Placebo; Assigned to Arm(s): Arm 1, Arm 2, Arm 3, Arm 4, Arm 5, Arm 6 | Intervention Type: DRUG; Name: Adalimumab; Assigned to Arm(s): Arm 7

Answer: A