Please select the eligibility criteria that correspond to the clinical trial below.
Title: A Randomized Trial Examining the Effectiveness of Mobile-Based Asthma Action Plans vs. Paper Asthma Action Plans
Brief Summary: The purpose of this study is to see if using a mobile phone application asthma action plan will help improve asthma management.


Options:
A: Inclusion Criteria:

* Asthma
* Receives asthma care at a clinic in Western Washington
* Has access to the internet at home

Exclusion Criteria:

* Does not speak or read English
B: Inclusion Criteria:

* Age ≥ 12 and ≤ 17 years.
* Access to Apple or Android based smart phone
* Mild to severe persistent asthma or poorly controlled asthma (see definitions below).

  o A different assessment of eligibility will be performed depending on whether or not the parent reports use of a preventive asthma medication at baseline. This is consistent with 2007 National Asthma Education Prevention Program recommendations that make a strong distinction between classifying asthma severity (for children not using preventive medications) and assessing control (for children using preventive medications). If a child has used a preventive medication in the past, but reports no use of the medication in the prior 3 months, we will assess severity.)
* Children not using a preventive medication at baseline: Assess for mild persistent to severe persistent asthma. Any 1 of the following, during the prior 4 weeks (as defined by parent interview in the waiting room) will determine severity:

  * An average of \>2 days per week with asthma symptoms
  * \>2 days per week with rescue medication use
  * ≥2 nights per month awakened with nighttime symptoms
  * Minor limitation of activity
  * ≥2 episodes of asthma during the past year that have required systemic corticosteroids
* Children using a preventive medication at baseline: Assess for poorly controlled asthma. Any 1 of the following, during the prior 4 weeks (as defined by parent interview in the waiting room) will determine control:

  * An average of \>2 days per week with asthma symptoms
  * \>2 days per week with rescue medication use
  * ≥2 nights per month awakened with nighttime symptoms
  * Some limitation of activity
  * ≥2 episodes of asthma during the past year that have required systemic corticosteroids.

Exclusion Criteria:

* Significant underlying respiratory disease other than asthma (such as cystic fibrosis or chronic lung disease) that could potentially interfere with asthma-related outcome measures.
* Significant co-morbid conditions (such as moderate to severe developmental delay, i.e. special education classroom or diagnosis) that could preclude participation in an education-based intervention.
* Inability to speak or understand English (child or parent).
* Children in foster care or other situations in which consent cannot be obtained from a guardian.
* Prior enrollment in the study.
C: Inclusion Criteria:

* 3-12 year old children with asthma requiring daily corticosteroid

Exclusion Criteria:

* sibling already in study
* physician excludes from participation
* non English Speaking
D: Inclusion Criteria:

* Patient's written informed consent obtained prior to any study-related procedures
* Male or female patient aged 18 years and above
* Patient with established diagnosis of asthma for at least 6 months
* Patient on maintenance therapy (Fixed dose combination ICS/LABA) with high dose of ICS
* Patient with ACT score \<20 at screening and at randomization
* Non- or ex-smoker who smoked ≤ 10 Pack-years prior to screening
* Patient must have their own Android® or iPhone operating system (IOS) smartphone
* Ability to use the pMDI device correctly

Exclusion Criteria:

* Patient with an asthma exacerbation or respiratory tract infection requiring systemic steroids and/or antibiotics within 1 to 3 month prior to screening
* Patient with a history of near-fatal asthma
* Clinically relevant and uncontrolled cardiac, hepatic, renal, gastrointestinal, endocrine, metabolic, neurologic, psychiatric or any other disorder that would put the safety of the subject at risk through participation, or which would affect the analysis
* Patient not able to be compliant with the study requirements.
* Patient with a BMI \> 40
* Patient working on night shifts
* Patient participating in the clinical phase of an interventional trial or have done so within the last 30 days prior to screening.
* Patient who has an already planned major surgery or hospitalization
* Female patient who is pregnant or lactating or who plans to become pregnant in the next 4 months.
* Patient with a history of hypersensitivity to any of the components of Foster pMDI

Answer: B