TrialPanorama/Dataset huggingface dataset:
Please select the eligibility criteria that correspond to the clinical trial below.
Title: A Multi-Centre Trial Evaluating Efficacy and Safety of Prophylactic Administration of Concizumab in Patients With Severe Haemophilia A Without Inhibitors
Brief Summary: This trial is conducted in Asia, Europe and the United States of America (USA). The aim of the trial is to assess the efficacy of concizumab administered s.c. (subcutaneously, under the skin) once daily in preventing bleeding episodes in patients with severe haemophilia A without inhibitors.


Options:
A: Inclusion Criteria:

* Male, aged 12 to 65 years
* Severe hemophilia A
* History of more than 150 exposure days (ED) with clotting factor concentrates
* Currently receiving episodic treatment with FVIII; no regular prophylaxis for more than 6 consecutive months in the past 5 years
* No current Factor VIII inhibitor or history of inhibitor
* Willing to use electronic patient diary

Exclusion Criteria:

* Presence of another bleeding disease that is different from hemophilia A
* Thrombocytopenia
* Abnormal renal function
* Presence of active liver disease
* Known hypersensitivity to FVIII
B: Key Inclusion Criteria:

* Subjects who have completed previous rFVIIIFc studies (NCT01181128, NCT02083965, NCT01458106 and NCT02502149)
* Ability to understand purposes and risks of the study and to provide signed and dated informed consent (or assent, as applicable).

Key Exclusion Criteria:

* Confirmed positive high-titer inhibitor (≥5.00 BU/mL).

NOTE: Other protocol defined Inclusion/Exclusion criteria may apply
C: Key Inclusion Criteria:

* Severe hemophilia A defined as \<1 IU/dL (\<1%) endogenous FVIII
* Male \<12 years of age and weight ≥13 kg
* History of at least 50 documented prior exposure days to FVIII
* No current, or history of, inhibitor development to FVIII

Key Exclusion Criteria:

* Other coagulation disorders in addition to Hemophilia A
* History of anaphylaxis associated with any FVIII or IV immunoglobulin administration

NOTE: Other protocol-defined Inclusion/Exclusion criteria may apply.
D: Inclusion Criteria: - Informed consent obtained before any trial-related activities. Trial-related activities are any procedures that are carried out as part of the trial, including activities to determine the suitability for the trial - Male patients aged 18 years or older at the time of signing informed consent, diagnosed with severe haemophilia A (FVIII activity below 1%), based on medical records or results at screening Exclusion Criteria: - Known or suspected hypersensitivity to trial product(s) or related products - Known inherited or acquired bleeding disorder other than haemophilia A - Presence of inhibitors (neutralising antibodies) to Factor VIII (equal to or above 0.6 Bethesda Units) at screening measured by the Nijmegen method

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Effectiveness of an Eye-Cervical Re-education Program (ECRP) to Decrease Pain and Increase Mobility in the Cervical Area Compared to a Combined Physiotherapy Protocol (CPP) in Patients With Chronic Neck Pain Symptoms.
Brief Summary: The aim of the present study is to value the effectiveness of an Eye-Cervical Re-education Program (ECRP) to decrease pain and increase mobility in the cervical area compared to a Combined Physiotherapy Protocol (CPP) in patients with chronic neck pain symptoms.


Options:
A: Inclusion Criteria:

* Patients with at least two weeks of neck pain
* Last episode starts at a maximum of one year ago
* Age between 18 and 70 years
* Patient is willing to undergo the treatment
* Neck pain is mechanical and can be provocated by movements or postures of the neck
* Neck pain is the main problem to treat
* Neck pain may also give pain in the upper arm or cervicogenic headaches

Exclusion Criteria:

* Appearance of "red flags"
* Cervical surgery in the past
* Pregnancy
* Whiplash trauma
* Health conditions with may disturb the treatment or makes it impossible to undergo the treatment.
* Not enough understanding of the Dutch questionnaires
* Undergoing treatments like physical therapy, manual therapy, osteopathy, chiropraxis, acupuncture, other types of exercise therapy during the last three months
B: Inclusion Criteria:

* Women aged between 18 and 65 years.
* Office workers working full time and performing at least 4 hours of computer work daily participated in this study
* \>15 on the Neck Disability Index (=NDI)
* Neck-shoulder pain related to trigger points

Exclusion Criteria:

* Following treatments for their complaints
* Systemic diseases
* Neurological symptoms
* Traumatic origin of the complaints
* Pregnancy
C: Inclusion Criteria:

* chronic neck pain (\> 30 days)
* neck disability index \>10
* not physical active on a daily basis

Exclusion Criteria:

* past history of whiplash injury or cervical surgery
* pain radiates to the upper limb with neurological deficit (reduced reflex, sensation, muscle strength)
* complain of vertigo
* cervical spine diseases: Spondylosis, Spondylolisthesis
D: Inclusion Criteria:

* Inclusion criteria were: to show symptoms and clinical signs of neck pain, have a medical diagnosis, meet the following lines according to the classification proposed by the Working Group "Bone and Joint Decade 2000-2010" (Axis 1:Health problem receiving health care, Axis II: tertiary care; healthcare in a private Physiotherapy center, Axis III: Grades I and II, Axis IV: Long term, more than three months, Line V: isolated, periodic or permanent Crises) and cervical pain of a mechanical origin, due to repetitive motion or maintenance of positions for long periods.

Exclusion Criteria:

* Dizziness syndrome, microwave contraindications and analgesic currents (therapeutic procedures used), post-traumatic, rheumatologic, neurological, infectious or tumor cervical pain.

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Guided Meditation as an Adjunct to Enhance Postoperative Recovery: A Feasibility Study
Brief Summary: The primary purpose of this trial is to test the feasibility of implementing a meditation program in the perioperative period.


Options:
A: Inclusion Criteria:

* Adults with overweight or obesity (estimated by BMI ≥ 25 and classified by the International Obesity Task Force, IOTF);
* Have asked for enrollment in nutritional treatment for weight loss in primary care units from Donostia-San Sebastian;
* Willingness to participate in the study.

Exclusion Criteria:

* Diagnosed with eating disorders; such as, Binge Eating Disorder, Anorexia or Bulimia;
* Diagnosed with any psychiatric disorder or intellectual disability that doesn't allow to carry out the intervention;
* Not to know sufficiently the language the intervention is carried out.
B: Inclusion Criteria:

1. 18 years of age or older
2. Undergoing any of the following types of cardiac surgery: CABG with or without valve surgery (aortic and/or mitral); isolated valve surgery; isolated aortic surgery
3. Surgery scheduled for at least 14 days after enrollment

Exclusion Criteria:

1. Urgent and/or emergent surgery
2. Non-English speaking
3. Cognitive impairment as defined by total MoCA score \< 10
4. Baseline DASS-21 depression score \>10
5. Pre-existing history of psychiatric illness as documented in the medical record or divulged in history taking in pre-enrollment patient interview, such as anxiety, depression, or bipolar disorder
6. History of cerebrovascular accident or recent history (\< 3 months) of seizures
7. History of dementia, Parkinson's disease, Alzheimer's disease, or other forms of cognitive decline
8. Current use of cognition enhancing drugs
9. Current management for chronic pain
10. Currently enrolled in another interventional study that could impact the primary outcome, as determined by the PI
11. Educational attainment below high school level or equivalent
12. Significant visual impairment
C: Inclusion Criteria:

* 25 to 60 years old
* Healthy individuals who have intentionally lost at least 5% of their body weight over the past year
* BMI \>20.5 kg/m2 at study entry and \>25 in past 2 years

Exclusion Criteria:

* Weight-loss surgery or medications
* Serious Psychiatric or medical conditions
* Substance abuse
* Ineligible for MRI
* Pregnant
* Eating disorder
D: Inclusion Criteria:

* Referral to DSME class at VA Pittsburgh Healthcare System University Drive Campus (VAPHS UD)
* Diagnosis of type 1 or type 2 diabetes
* Hemoglobin A1C \>7.0%
* Problem Areas in "Diabetes Scale (PAID) -5" score =/ \>3 or "Diabetes Distress Scale -2" =/\>2 score indicating the presence of Diabetes-related Distress

Exclusion Criteria:

* Documented cognitive impairment that would interfere with the ability to comprehend the informed consent and actively participate in the study
* Previous attendance of VA DSME class within the past 12 months
* Currently active mindfulness practice

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: A Study of the Management of the Patient's Disease Based on the Life Log Data of Patients With Lifestyle-related Diseases Through a Wearable Device
Brief Summary: In order to study the effectiveness of personalized healthcare intervention for lifestyle-related diseases, investigators designed this study using mobile application and clinical feedback from clinicians


Options:
A: DISEASE CHARACTERISTICS:

* Overdue for colorectal cancer screening (identified using automated extracts from the electronic medical record), as defined by the following criteria:

  * No fecal occult blood test within the past 12 months
  * No flexible sigmoidoscopy within the past 5 years
  * No colonoscopy within the past 10 years
* Receiving primary care at a Harvard Vanguard Medical Associates (HVMA) center
* Registered to use the HVMA patient portal (MyHealth) AND has an active MyHealth account

PATIENT CHARACTERISTICS:

* Not specified

PRIOR CONCURRENT THERAPY:

* See Disease Characteristics
B: Inclusion Criteria:

* Speaks English or Spanish
* Admitted to unit where study is ongoing

Exclusion Criteria:

* Does not pass Mini-mental status exam
C: Inclusion Criteria:

* \>= 18 years of age
* Have a designated Palo Alto Medical Foundation Primary Care Provider (PCP)
* Seen in primary or specialty care at the Palo Alto Division at least once in the preceding 24 months
* Diagnosis of diabetes
* Baseline A1C \>= 7.5%

Exclusion Criteria:

* Initial diagnosis of diabetes within the last 12 months
* Diagnosis of Type 1 diabetes
* Inability to speak and read in English
* Lack of regular access to a computer with Internet and email capabilities
* Unwilling to perform any self-monitoring at home, including blood glucose and blood pressure%
* Pregnant, planning to become pregnant, or lactating
* Currently enrolled in a care management program at Palo Alto Medical Foundation or elsewhere
* PCP determination that the study is inappropriate or unsafe for the patient
* Investigator discretion for clinical safety or protocol adherence reasons
D: Inclusion Criteria:

* Study participants must agree to support by him/herself at enroll time
* Patients without severe cardiopulmonary disease, cancer, or other acute diseases
* Patients must be over BMI \> 23 kg/m2

Exclusion Criteria:

* Patient who did not agree with this study
* Patients with severe cardiopulmonary disease, cancer, or other acute diseases
* Patients who were pregnant

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: iCanCope With Sickle Cell Disease: A Mobile Pain Management Intervention for Adolescents
Brief Summary: The project will test a tailored web and smartphone-based application (iCanCope with SCD) to improve pain self-management and functioning in youth (aged 12-18) with sickle cell disease. The program will include goal setting, peer-based social support, and pain self-management training. The investigators will determine initial program effectiveness through a pilot three-site randomized controlled trial in 160 youth randomized to treatment compared to attention control.


Options:
A: Inclusion Criteria:

* aged between 12-18 years
* diagnosed with any type of SCD
* able to speak and read English
* score at least 4 (indicating some days with pain interference over the past month) on the Sickle Cell Pain Burden Interview
* willing and able to complete online measures

Exclusion Criteria:

* significant cognitive limitations that would impair their ability to use and understand the iCanCope with SCD program, as per their healthcare provider or parent
* have previously received more than 4 sessions of outpatient psychological therapy for pain management in the 6 months prior to the time of screening.
B: Inclusion Criteria:

* Age 8-18 years
* Diagnosis of childhood fibromyalgia or chronic musculoskeletal pain (ACR criteria)

Exclusion Criteria:

* Co-morbidity with cardiac, pulmonary or metabolic disease.
* Children who engage in more than 3 hours of structured extracurricular physical activity programs weekly, unless a physiotherapy pool program with emphasis on joint range of motion and stretching.
* Children who are unable to cooperate with testing procedures.
C: Inclusion Criteria:

* adolescents 12 to 18 years
* diagnosed with JIA,
* able to speak and read English or French
* able to complete baseline online outcome measures.

Exclusion Criteria:

* cognitive impairment
* major co-morbid illnesses (medical or psychiatric) which may impact their ability to understand and use the web-based program.
D: Inclusion Criteria:

* Pain in neck or back equal to or greater than 3 on an 11-box numerical rating scale for more than three days.

Exclusion Criteria:

* If a serious pathology or injury is suspected, the child will be referred to a secondary care sports injury center for diagnostic work-up and/or imaging.
* Handicaps which prevents normal physical activity.

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Wise App Trial for Improving Health Outcomes in People Living With HIV
Brief Summary: The overall goal of this study is to design a user-centered design app linked to a smart pill box for people living with HIV (PLWH) and evaluate its effects in a randomized controlled trial. The proposed trial is scientifically significant in representing a principled and systematic effort to test the efficacy of a smartphone intervention linked to a smart pill box for antiretroviral (ART) adherence in PLWH in the United States (US). Guided by a strong theoretical framework building on earlier user-centered design work and integrating a real-time monitoring device, this work has the potential to improve ART adherence in PLWH and have a sustainable public health impact.


Options:
A: Inclusion Criteria:

In the Randomized Controlled Trial we will recruit a minimum of 4000 women, aged 30 and older living in the province of Jujuy, Argentina.

Inclusion criteria are:

1. Having performed self-collection of HPV-testing.
2. Mentally competent to understand the consent form.
3. Able to communicate with study staff.
4. Being able to provide a mobile phone telephone number.

Exclusion Criteria:

* Current pregnancy.
* Women with Mental disability.
B: Inclusion Criteria:

* Newly diagnosed HIV positive clients presenting at selected public health facilities, irrespective of CD4 count
* Access to an Android smartphone with data
* Willing to pay the (very small) cost to access their laboratory result
* Age - 18 years and older
* Proof of ID/passport/refugee number (for identification/security, and to confirm the single patient identifier)
* Can read English or Zulu
* Ability and willingness to sign informed consent

Exclusion Criteria:

* Clients presenting for antenatal care services, as these women will be enrolled in the national MomConnect program
* Refusal to participate
C: Inclusion Criteria:

* Have a diagnosis of HIV
* Report past 30 days adherence of 80% or less as measured using the Visual Analogue Scale (VAS), or have a viral load of over 400 copies/mL
* Be able to communicate and read in English or Spanish
* Live in the US
* Have a smartphone
* Be taking ART medications

Exclusion Criteria:

* Participation in any other mobile app study for PLWH, including text messaging studies
* Diagnosis of a clinical problem that would preclude someone from using a smartphone
D: Inclusion Criteria:

* African American or Latina female and sexually active with a male partner(s) within the past 6 months,
* age 15 to 29 years
* present for contraception initiation
* English speaking

Exclusion Criteria:

* not currently pregnant or intending pregnancy within the next 6 months
* and not currently using LARC
* not highly intending LARC at enrollment

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Wise App Trial for Improving Health Outcomes in People Living With HIV
Brief Summary: The overall goal of this study is to design a user-centered design app linked to a smart pill box for people living with HIV (PLWH) and evaluate its effects in a randomized controlled trial. The proposed trial is scientifically significant in representing a principled and systematic effort to test the efficacy of a smartphone intervention linked to a smart pill box for antiretroviral (ART) adherence in PLWH in the United States (US). Guided by a strong theoretical framework building on earlier user-centered design work and integrating a real-time monitoring device, this work has the potential to improve ART adherence in PLWH and have a sustainable public health impact.


Options:
A: Inclusion Criteria:

* Newly diagnosed HIV positive clients presenting at selected public health facilities, irrespective of CD4 count
* Access to an Android smartphone with data
* Willing to pay the (very small) cost to access their laboratory result
* Age - 18 years and older
* Proof of ID/passport/refugee number (for identification/security, and to confirm the single patient identifier)
* Can read English or Zulu
* Ability and willingness to sign informed consent

Exclusion Criteria:

* Clients presenting for antenatal care services, as these women will be enrolled in the national MomConnect program
* Refusal to participate
B: Inclusion Criteria:

* Have a diagnosis of HIV
* Report past 30 days adherence of 80% or less as measured using the Visual Analogue Scale (VAS), or have a viral load of over 400 copies/mL
* Be able to communicate and read in English or Spanish
* Live in the US
* Have a smartphone
* Be taking ART medications

Exclusion Criteria:

* Participation in any other mobile app study for PLWH, including text messaging studies
* Diagnosis of a clinical problem that would preclude someone from using a smartphone
C: Inclusion Criteria:

* Pregnant; at least 28 weeks gestation
* HIV negative
* Daily access to a mobile phone
* Planning to stay in area for 6 months postpartum
* Able to read/write or has trusted person to help

Exclusion Criteria:

* Does not meet above criteria
D: Inclusion Criteria:

* Gender: Female
* Age Limit: 18-20
* Must have daily access to a smartphone that receives text messages and can access to the Internet
* Must speak English or Spanish
* Must live in the United States or a U.S. territory

Exclusion Criteria:

* Currently pregnant or trying to get pregnant

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Wise App Trial for Improving Health Outcomes in People Living With HIV
Brief Summary: The overall goal of this study is to design a user-centered design app linked to a smart pill box for people living with HIV (PLWH) and evaluate its effects in a randomized controlled trial. The proposed trial is scientifically significant in representing a principled and systematic effort to test the efficacy of a smartphone intervention linked to a smart pill box for antiretroviral (ART) adherence in PLWH in the United States (US). Guided by a strong theoretical framework building on earlier user-centered design work and integrating a real-time monitoring device, this work has the potential to improve ART adherence in PLWH and have a sustainable public health impact.


Options:
A: Inclusion Criteria:

* Have a diagnosis of HIV
* Report past 30 days adherence of 80% or less as measured using the Visual Analogue Scale (VAS), or have a viral load of over 400 copies/mL
* Be able to communicate and read in English or Spanish
* Live in the US
* Have a smartphone
* Be taking ART medications

Exclusion Criteria:

* Participation in any other mobile app study for PLWH, including text messaging studies
* Diagnosis of a clinical problem that would preclude someone from using a smartphone
B: Inclusion Criteria:

* the mother has access to a cell phone (either her own phone or the phone of a household member)
* the mother lives in the uptake area of the health center.

Exclusion Criteria:

* the mother does not have access to a mobile phone.
C: Inclusion Criteria:

* Living with HIV
* Reads English and speaks English or a local language (e.g., Twi)
* On antiretroviral therapy
* Access to mobile phone throughout study period
* Able to give consent and not impaired by cognitive or medical limitations as per clinical assessment
* Not involved with another HIV prevention or adherence study
* Evidence of a detectable viral load

Exclusion Criteria:

* None
D: Inclusion Criteria:

* Parents of adolescents aged 10 - 17 who have had at least 1 dose of HPV
* Patients aged 18 - 21 who have had at least 1 dose of HPV

Exclusion Criteria:

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: RCT: Effect of Coaching on Mid-Career Physician Well-Being, Job Satisfaction, and Fulfillment
Brief Summary: The study will assess the effect of individualized professional coaching for mid-career family medicine and general internal medicine physicians on burnout, job satisfaction, and professional fulfillment.


Options:
A: Inclusion Criteria:

* University students with a standard deviation score below the sample mean on the Connor-Davidson Resilience Scale (CDRISC-25).
* Adequate knowledge to understand and read Spanish and/or be Spanish-speaking.
* Internet access and computer skills.

Exclusion Criteria:

* University students who are on a waiting list for psychotherapy or who are or have been undergoing psychotherapy in the last 12 months.
* Individuals with a current or past psychotic or bipolar disorder.
* Individuals at risk of suicide.
B: Inclusion Criteria:

* Workers over the age of 19 and under 65
* In the Perceived Stress Scale 14 points or more
* If you are currently taking medication due to psychiatric illnesses such as depression, anxiety disorder, insomnia, etc., if the stabilizer is expected to have no change in drug dose during the clinical trial
* If you understand the protocol and voluntarily agree to participate
* If you have an Android phone

Exclusion Criteria:

* Age under 19, adult over 65
* If you have dementia, intellectual disability, or other cognitive impairment
* If you have convulsive disorder, stroke, or other neurological disorder
* If you have psychosis such as schizophrenia or bipolar disorder or you have a history
* If you have a disease that can affect the reliability of HRV test, such as heart disease or lung disease.
* Has received non-pharmacological psychiatric or counseling treatment within the current or last 6 months.
C: Inclusion Criteria:

* Medical doctors across all specialties and professional grades who have a regular contact with patients and works in the United Kingdom.
D: Inclusion Criteria

1. General internal medicine and family physicians
2. In practice for 5-30 years

Exclusion Criteria:

1. physicians who specialize in areas other than general internal medicine and family medicine
2. physicians who have been in practice less than 5 years or more than 30 years

Answer: D