Please select the eligibility criteria that correspond to the clinical trial below.
Title: Prostatic Artery Embolization vs. Conventional Transurethral Prostatectomy in the Treatment of Benign Prostatic Hyperplasia: A Prospective Randomized Trial
Brief Summary: Benign prostatic hyperplasia (BPH) is a prevalent entity, affecting over 50% of men older than 60 years. The clinical picture of the disease includes lower urinary tract symptoms such as interrupted and weak urinary stream, nocturia, urgency and leaking and even sexual dysfunction in some individuals. Medical therapy is usually the first-line treatment. However, the efficacy of drugs like alpha-blockers is limited, and as disease progresses more invasive treatment options have to be taken into consideration. In cases with moderate to severe lower urinary tract symptoms (LUTS) transurethral resection of the prostate (TUR-P) is the standard treatment. TURP, however, is limited to prostates smaller than 60-80ml and the procedure is associated with a complication rate. The cumulative short-term morbidity rate is around 11% and the necessity for surgical revision is as high as 6%. Bleeding requiring transfusions and transurethral resection syndrome represent potentially serious threats to elderly and frail patients. Prostatic artery embolization (PAE) has been suggested as a minimal invasive alternative procedure, which can be performed in an outpatient setting with rapid recovery and low morbidity.

The investigators hypothesize that PAE is non-inferior in the treatment of symptomatic BPH compared to conventional and established TUR-P.


Options:
A: Inclusion Criteria:

* Males age of 50 years or older diagnosed with symptomatic benign prostatic hyperplasia (BPH)

Exclusion Criteria:

* Size, volume,length of prostate
B: Inclusion Criteria:

• Men \>50 years old with moderate-severe BPH

Exclusion Criteria:

* Size, width of prostate
* Other medical condition or co-morbidity contraindicative for TURP or UroLift
C: Inclusion Criteria:

* Aged 40 years or older on the date of survey
* Able to read local language
* Able to access the internet and use a computer (with or without the help of an assisting person who may or may not be a family member)
* Provides of informed consent

Exclusion Criteria:

* Is pregnant
* Diagnosed as having urinary tract infection by a physician in the past one month which may be cured or persisting
D: Inclusion Criteria:

* Men older than 40
* Patient must be a candidate for TURP
* Refractory to medical therapy or patient is not willing to consider (further) medical treatment
* Patient has a prostate size of at least 25 ml and not more than 80 ml, measured by ultrasound
* IPSS ≥8
* QoL ≥3
* Qmax\<12 and/or urinary retention
* Written informed consent

Exclusion Criteria:

* Mild symptoms (IPSS \<8)
* Severe atherosclerosis
* Severe tortuosity in the aortic bifurcation or internal iliac arteries
* Acontractile detrusor
* Neurogenic lower urinary tract dysfunction
* Urethral stenosis
* Bladder diverticulum
* Bladder stone with surgical indication
* Allergy to intravenous contrast media
* Contraindication for MRI imaging
* Preinterventionally proven adenocarcinoma of the prostate
* Renal failure (GFR\<60ml/min)

Answer: D