Please select the eligibility criteria that correspond to the clinical trial below.
Title: LA Health: A Prospective Study of Primary and Secondary Obesity Prevention in Children and Adolescents
Brief Summary: There is a worldwide pandemic of obesity with far-reaching consequences for the health of our nation. Obesity is the second leading cause of preventable death in the United States. Prevention of obesity, especially in children, has been deemed by public health policy makers to be one of the most important objectives for our country.


Options:
A: School inclusion criteria:

* Public middle schools in which a majority of students lived in the surrounding community
* Enrollment of at least 90 8th-grade girls
* Yearly withdrawal rates less than 28%
* At least one semester of physical education required for each grade
* Willingness to sign a memorandum of understanding and accept random assignment of the school

Student exclusion criteria:

* Limited English-speaking skills
* Unable to participate in physical education classes due to a medical condition or disability
* Contraindications for participating in a submaximal exercise test
B: Inclusion Criteria:

* Normal, Overweight and Obese Children: Investigators will attempt to obtain a natural selection of normal weight children (age- \& sex-specific BMI \< 85th percentile based on CDC BMI growth charts (40) and overweight and obese children (BMI ≥ 85th percentile). Based on preliminary data from these areas, investigators expect that at least 50% of the sample will be overweight or obese. There will not be an upper BMI limit.

Gender \& Age: Investigators will attempt to enroll equal numbers of female and male students in 3rd through 5th grades (8-12 years of age).

Latino origin: This study will include all ethnicities, however the selected schools are \>90% Latino.

Exclusion Criteria:

* The following criteria are exclusionary: presently taking medication(s) or diagnosed with any disease that could influence dietary intake or body composition; previously diagnosed with any major illness since birth (e.g. chronic birth asphyxia, cancer, etc.); any physical, cognitive, or psychological disability that would prevent participation in the study. Participants testing positive for diabetes (as determined from the fasting blood draw) will be referred for treatment. (Note: subjects with pre-diabetes will be eligible for the study). Although participant data may be excluded based on the above exclusion criteria, participation in the program classes may be allowed. Individual cases will be reviewed as they arise.
C: Inclusion Criteria:

* Being one of the LA GEAR UP middle schools or a feeder elementary school
* Having an enrollment of at least 100 students per school
* All students in grades 4-6 of participating schools

Exclusion Criteria:

-
D: Inclusion Criteria:

* Middle school student body is at least 50% minority (defined as African American, Hispanic/Latino, and/or Native American) and/or greater than 50% eligible for free or reduced lunch.
* Middle school annual school-wide attrition from all causes is \<= 25% (estimate determined from data provided by the school).
* Middle school expected cohort size at end of study is at least 50 per school determined by applying 50% anticipated enrollment rate and annual school-wide attrition rate over 3 years.
* Student able to participate in the school's standard PE program.
* Student's parent/guardian has provided informed consent for the child to participate in data collection and evaluation procedures.
* Student has provided informed assent to participate in data collection and evaluation procedures.

Exclusion Criteria: (none specified)

Answer: C