Please select the eligibility criteria that correspond to the clinical trial below.
Title: N/A
Brief Summary: Minor mental health problems, MMHP, like mild depression and anxiety, and medically unexplained symptoms, MUS, symptoms with no known underlying organic disease, are strongly associated to each other. MMHP and MUS have an impact on well-being and quality of life, lead to impaired social and cognitive function and could result in reduced work capacity. The investigators have designed the present study as a pragmatic trial to investigate the effectiveness of an integrative treatment model, therapeutic acupuncture, versus conventional treatment in patients with MMHP or MUS in primary care. The investigators examined whether the effects of the integrative treatment model differed from those achieved with therapeutic acupuncture or conventional treatment. Primary endpoints were anxiety and depression (assessed with the Hospital Anxiety and Depression scale), health-related quality of life (SF-36) and coping with stress, sense of coherence (SOC) during the eight weeks of treatment interventions.

Statistical power was calculated based on an expected 50% reduction in HAD anxiety and depression scores after eight weeks of integrative treatment; a 30% reduction in acupuncture; and 20% in conventional care. A total of 120 (40/arm) were needed to achieve a power of 83% at p \<0.05. Treatment effects were calculated as the difference between values at baseline, after four weeks and after the complete intervention period, i.e. after eight weeks. Nonparametric analyses were carried out to test differences between independent samples (Kruskal-Wallis and Mann-Whitney U) and related samples (Wilcoxon).


Options:
A: Inclusion Criteria:

* most recently experience an ischemic or hemorrhagic stroke, documented by cerebral computed topographic scanning or magnetic resonance imaging
* develop significant depression, with a HAMD-17 score of 16 or greater

Exclusion Criteria:

* presence of severe aphasia, especially fluent aphasia
* presence of severe cognitive dysfunction, indicated the Mini-mental State Examination (MMSE) score of \< 18
* had a history of psychiatric illness other than depression
* presence of another chronic disorder, including severe Parkinson's disease, cardiac disease, cancers, epilepsy, or chronic alcoholism
* impaired hepatic or renal function
* have bleeding tendency
B: Inclusion Criteria:

* one or more symptoms of emotional and physical fatigue
* worry
* anxiety
* depression
* sleep disturbances or somatic pain

Exclusion Criteria:

* 100% sick leave \> 2,5 years
* pregnancy
* cancer
* personality disorders
* substance use disorders or prescribed sedative drugs
C: Inclusion Criteria:

* Willing to give informed consent;
* Hong Kong resident;
* Age 18-65 years;
* Previous DSM-IV Major Depressive Disorder as confirmed with the Structured Clinical Interview for DSM-IV;
* Hamilton Depression Rating Scale scores of 18 or below for at screening and baseline visit;
* A chief complaint of insomnia;
* Able to comply with the trial protocol.

Exclusion Criteria:

* Any symptoms suggestive of specific sleep disorders, including loud snoring, periodic leg movement, parasomnia;
* A diagnosis of sleep apnea or periodic limb movement disorder (PLMD) as assessed by overnight polysomnography (PSG);
* Presence of suicidal risk;
* Previous history of schizophrenia, other psychotic disorders, and bipolar disorder;
* Pregnant, breast-feeding, or woman of childbearing potential not using adequate contraception;
* Infection or abscess close to the site of selected acupoints and in the investigator's opinion inclusion is unsafe.
D: Inclusion Criteria:

* Patients with documented stable, ischemic heart disease who have finished heart rehabilitation according to the National Guidelines \> 6 months ago Actual use of aspirin, statins, and blood pressure medication according to the National Guidelines
* Age \< 75 years
* Increased pressure pain sensitivity ≥60 as a sign of persistent stress

Exclusion Criteria:

* Previous diagnosed and treated psychiatric disease besides depression Other Chronic Disease with known significantly reduced life expectancy (as cancer or severe COPD)
* Other Chronic Disease with known significantly reduced Quality of Life as COPD, chronic pain conditions (but not diabetes or heart disease)
* Planned heart operation
* Changed Medication for the Heart (concerning Angina or Heart Failure) within one month
* Previous use of the Pressure Pain Sensitivity Device followed by treatment with Acupressure

Answer: B