Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Local Anesthetic Use at Iliac Crest Bone Graft Site in Spinal Reconstructive Surgery
Brief Summary: The use of iliac crest bone graft (ICBG) remains the gold-standard in spinal reconstructive surgery for achieving fusion. Major complications from the harvesting of ICBG are rare, but chronic pain has been reported in 10-39%. Catheters implanted at the time of surgery have been used to provide local anesthetic at the harvest site for 24-48 hours after surgery. This has been shown to decrease chronic pain at 4 years post-operatively. A single application of local anesthetic at surgery has been shown to decrease pain at the harvest site for up to 5 days. No study has demonstrated a benefit to using a single application of local anesthetic at the ICBG site beyond 5 days. In current clinical practice, the use of a local anesthetic at the ICBG site is determined according to surgeon preference. The purpose of this study is to determine if a single application of bupivacaine at the ICBG site, as currently done in some cases, provides any pain relief beyond 5 days such as that demonstrated with longer infusions of local anesthetics.


Options:
A: Arm Label: Injection with Saline; Type: PLACEBO_COMPARATOR; Interventions: Procedure: Infiltration with Saline | Arm Label: Injection with Bupivacaine; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Infiltration with Bupivacaine | Intervention Type: PROCEDURE; Name: Infiltration with Saline; Assigned to Arm(s): Injection with Saline | Intervention Type: PROCEDURE; Name: Infiltration with Bupivacaine; Assigned to Arm(s): Injection with Bupivacaine
B: Arm Label: Patients who had inguinal herniorraphy.; Type: N/A; Interventions: Procedure: Inguinal herniorraphy. | Arm Label: Patients who had hysterectomy.; Type: N/A; Interventions: Procedure: Hysterectomy. | Arm Label: Patients who had thoracotomy.; Type: N/A; Interventions: Procedure: Thoracotomy . | Intervention Type: PROCEDURE; Name: Inguinal herniorraphy.; Assigned to Arm(s): Patients who had inguinal herniorraphy. | Intervention Type: PROCEDURE; Name: Hysterectomy.; Assigned to Arm(s): Patients who had hysterectomy. | Intervention Type: PROCEDURE; Name: Thoracotomy .; Assigned to Arm(s): Patients who had thoracotomy.
C: Arm Label: Bupivacaine; Type: ACTIVE_COMPARATOR; Interventions: Drug: Bupivacaine | Arm Label: Saline; Type: PLACEBO_COMPARATOR; Interventions: Other: Normal Saline | Intervention Type: DRUG; Name: Bupivacaine; Assigned to Arm(s): Bupivacaine | Intervention Type: OTHER; Name: Normal Saline; Assigned to Arm(s): Saline
D: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Procedure: perioperative epidural catheter | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Procedure: perioperative epidural catheter | Arm Label: 3; Type: ACTIVE_COMPARATOR; Interventions: Procedure: perioperative epidural catheter | Arm Label: 4; Type: ACTIVE_COMPARATOR; Interventions: Procedure: perioperative epidural catheter | Arm Label: 5; Type: PLACEBO_COMPARATOR; Interventions: Procedure: perioperative epidural catheter | Intervention Type: PROCEDURE; Name: perioperative epidural catheter; Assigned to Arm(s): 1, 2, 3, 4, 5

Answer: C