Please select the eligibility criteria that correspond to the clinical trial below.
Title: Community-based Rehabilitation Training After Stroke: a Pilot Randomised Controlled Trial
Brief Summary: A pilot study that will evaluate the feasibility and acceptability of procedures to inform the design and delivery of a definitive RCT of ReTrain (which would assess the clinical and cost effectiveness of ReTrain for stroke survivors).


Options:
A: Inclusion Criteria:

* first hospitalization with a diagnosis of stroke (previous experience of adjustment to stroke may influence outcomes),
* discharge from acute care hospital, inpatient rehabilitation or outpatient occupational therapy to a non-institutionalized setting,
* FIM scores at rehabilitation discharge of at least 3 for expression, comprehension, memory and problem-solving (to ensure potential participants' ability to participate in coaching process) and
* live within the City of Ottawa.

Exclusion Criteria:

* Those discharged from acute or inpatient rehabilitation and are referred to outpatient stroke rehabilitation for occupational therapy will be excluded until they complete their outpatient occupational therapy (due to potential overlap of client goals while in outpatient occupational therapy)
* have other degenerative neurological diagnoses (such as Parkinson's, Multiple Sclerosis) or
* have a current major depressive or psychotic disorder.
B: Inclusion Criteria:

Patients will be enrolled according to the following criteria:

* MCI defined according to Winblad et al. criteria;
* Evidence of impairment across attention neuropsychological tests;
* Evidence on MRI of subcortical vascular lesions: moderate to severe age-related white matter changes (WMC) according to a modified version of the Fazekas scale.

Exclusion Criteria:

* Age \< 18 years
C: Inclusion Criteria:

* to be over 18 years old,
* to have been diagnosed with stroke
* an occurrence of the injury of 12 month period ore more (chronic stage)
* cognitive impairment confirmed by pre-intervention neuropsychological assessment

Exclusion Criteria:

* diagnosis of language deficits or aphasia
* motor impairment concerning upper limbs that may incapacitate them for the use of the computer
* severe alteration of the visual field or perceptual problems
* health status that may require further intervention or admission to a medical center during the study;
* neurological or psychiatric history
* substance abuse.
D: Inclusion Criteria:

* Primary clinical diagnosis of stroke (assessed by referring clinician/GP records)
* \>1 month (but no upper limit) since discharge from NHS physical rehabilitation services at randomisation
* Able to walk independently indoors with or without mobility aids, but has self-reported difficulty or requires help on stairs, slopes or uneven surfaces (assessed by recruiting team using standard tools)
* Willingness to be randomised to either control or ReTrain (and attend the training venue)
* Cognitive capacity and communication ability sufficient to participate in the study (assessed by recruiting team using standard tools).24 NB: Criterion (3) has been selected pragmatically to maximise eligibility while ensuring participants have a mobility deficit that could be addressed by the intervention. Eligible people with aphasia will not be excluded.

Exclusion Criteria:

* \<18 years old
* Contraindications to moderate to vigorous physical activity. Used in GP screening assessment form. (Adapted from ACSM guidelines 25) Contraindications include:

  * Acute or uncontrolled heart failure
  * Unstable or uncontrolled angina
  * Uncontrolled cardiac dysrhythmia causing symptoms or haemodynamic compromise
  * Symptomatic severe aortic stenosis
  * Current deep vein thrombosis, pulmonary embolus or pulmonary infarction
  * Acute myocarditis or pericarditis
  * Suspected or known dissecting aneurysm
  * Unstable / uncontrolled blood pressure
  * Systolic blood pressure \> 160
  * Diastolic blood pressure \> 100
  * Acute systemic infection
  * Uncontrolled diabetes

Answer: D