Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Tolerance and Effect of Antipsychotics in Children and Adolescents With Psychosis- An Investigator-initiated, Phase IV, Randomised Double-blind Multi-centre Trial of the Benefits and Harms of Aripiprazole Versus Quetiapine in Children and Adolescents With Psychosis
Brief Summary: The benefits and harms of antipsychotics are relatively well studied in adults. However, there is a lack of scientifically valid studies regarding the benefits and harms of antipsychotics in children and adolescents with psychosis.

The main objective of the TEA trial is to compare the efficacy and adverse reactions of two antipsychotics (quetiapine versus aripiprazole) in children and adolescents between 12-17 years of age with psychotic symptoms on psychopathology, cognitive deficits, and daily functioning. Furthermore, the trial will focus on adverse reaction profiles of the two antipsychotics as well as early predictors of later sustained clinical effects of these antipsychotics.


Options:
A: Arm Label: GC; Type: EXPERIMENTAL; Interventions: Behavioral: Genetic Counseling | Arm Label: EB; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Educational Booklet | Arm Label: WT; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Genetic Counseling; Assigned to Arm(s): GC | Intervention Type: BEHAVIORAL; Name: Educational Booklet; Assigned to Arm(s): EB
B: Arm Label: Assignment to FORNET; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: FORNET | Arm Label: Assignment to CBT; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: CBT | Arm Label: Waiting List Control Group (camp); Type: OTHER; Interventions: Other: Waiting List Control Group (camp) | Arm Label: Waiting List Control Group (no camp); Type: OTHER; Interventions: Other: Waiting List Control Group (no camp) | Intervention Type: BEHAVIORAL; Name: FORNET; Assigned to Arm(s): Assignment to FORNET | Intervention Type: BEHAVIORAL; Name: CBT; Assigned to Arm(s): Assignment to CBT | Intervention Type: OTHER; Name: Waiting List Control Group (camp); Assigned to Arm(s): Waiting List Control Group (camp) | Intervention Type: OTHER; Name: Waiting List Control Group (no camp); Assigned to Arm(s): Waiting List Control Group (no camp)
C: Arm Label: Aripirazole; Type: EXPERIMENTAL; Interventions: Drug: Aripiprazole | Arm Label: Quetiapine prolong; Type: EXPERIMENTAL; Interventions: Drug: Quetiapine | Intervention Type: DRUG; Name: Aripiprazole; Assigned to Arm(s): Aripirazole | Intervention Type: DRUG; Name: Quetiapine; Assigned to Arm(s): Quetiapine prolong
D: Arm Label: Prolonged Exposure (CBT); Type: EXPERIMENTAL; Interventions: Procedure: Cognitive Behavioral Therapy | Arm Label: Cognitive Therapy; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Cognitive Therapy | Arm Label: SSRI (escitalopram); Type: EXPERIMENTAL; Interventions: Drug: Escitalopram | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Arm Label: Waiting List; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: PROCEDURE; Name: Cognitive Behavioral Therapy; Assigned to Arm(s): Prolonged Exposure (CBT) | Intervention Type: PROCEDURE; Name: Cognitive Therapy; Assigned to Arm(s): Cognitive Therapy | Intervention Type: DRUG; Name: Escitalopram; Assigned to Arm(s): SSRI (escitalopram) | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Placebo

Answer: C