Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Randomized Phase II/III Trial of Paclitaxel Plus Carboplatin With or Without Bevacizumab (NSC #704865) in Patients With Advanced Nonsquamous NSCLC
Brief Summary: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies, such as bevacizumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or deliver cancer-killing substances to them. Combining chemotherapy with a monoclonal antibody may kill more tumor cells. This randomized phase II/III trial is to see if combination chemotherapy works better with or without bevacizumab in treating patients who have advanced, metastatic, or recurrent non-small cell lung cance


Options:
A: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: Cisplatin, Drug: Gemcitabine, Drug: bevacizumab [Avastin] | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Drug: Cisplatin, Drug: Gemcitabine, Drug: bevacizumab [Avastin] | Arm Label: 3; Type: PLACEBO_COMPARATOR; Interventions: Drug: Cisplatin, Drug: Gemcitabine, Drug: Placebo | Intervention Type: DRUG; Name: Cisplatin; Assigned to Arm(s): 1, 2, 3 | Intervention Type: DRUG; Name: Gemcitabine; Assigned to Arm(s): 1, 2, 3 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): 3 | Intervention Type: DRUG; Name: bevacizumab [Avastin]; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: bevacizumab [Avastin]; Assigned to Arm(s): 2
B: Arm Label: Arm I (paclitaxel and carboplatin); Type: EXPERIMENTAL; Interventions: Drug: paclitaxel, Drug: carboplatin, Other: laboratory biomarker analysis | Arm Label: Arm II (paclitaxel, carboplatin, and bevacizumab); Type: EXPERIMENTAL; Interventions: Drug: paclitaxel, Drug: carboplatin, Biological: bevacizumab, Other: laboratory biomarker analysis | Intervention Type: DRUG; Name: paclitaxel; Assigned to Arm(s): Arm I (paclitaxel and carboplatin), Arm II (paclitaxel, carboplatin, and bevacizumab) | Intervention Type: DRUG; Name: carboplatin; Assigned to Arm(s): Arm I (paclitaxel and carboplatin), Arm II (paclitaxel, carboplatin, and bevacizumab) | Intervention Type: BIOLOGICAL; Name: bevacizumab; Assigned to Arm(s): Arm II (paclitaxel, carboplatin, and bevacizumab) | Intervention Type: OTHER; Name: laboratory biomarker analysis; Assigned to Arm(s): Arm I (paclitaxel and carboplatin), Arm II (paclitaxel, carboplatin, and bevacizumab)
C: Arm Label: Pemetrexed + Cisplatin; Type: EXPERIMENTAL; Interventions: Drug: Pemetrexed, Drug: Cisplatin | Arm Label: Pemetrexed + Carboplatin; Type: EXPERIMENTAL; Interventions: Drug: Pemetrexed, Drug: Carboplatin | Intervention Type: DRUG; Name: Pemetrexed; Assigned to Arm(s): Pemetrexed + Carboplatin, Pemetrexed + Cisplatin | Intervention Type: DRUG; Name: Cisplatin; Assigned to Arm(s): Pemetrexed + Cisplatin | Intervention Type: DRUG; Name: Carboplatin; Assigned to Arm(s): Pemetrexed + Carboplatin
D: Arm Label: Pembrolizumab; Type: EXPERIMENTAL; Interventions: Drug: Pembrolizumab | Arm Label: Paclitaxel+Carboplatin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Paclitaxel, Drug: Carboplatin, Drug: Pemetrexed | Arm Label: Pemetrexed+Carboplatin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Carboplatin, Drug: Pemetrexed | Arm Label: Pemetrexed+Cisplatin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Pemetrexed, Drug: Cisplatin | Arm Label: Gemcitabine+Carboplatin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Carboplatin, Drug: Gemcitabine | Arm Label: Gemcitabine+Cisplatin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Cisplatin, Drug: Gemcitabine | Intervention Type: DRUG; Name: Pembrolizumab; Assigned to Arm(s): Pembrolizumab | Intervention Type: DRUG; Name: Paclitaxel; Assigned to Arm(s): Paclitaxel+Carboplatin | Intervention Type: DRUG; Name: Carboplatin; Assigned to Arm(s): Gemcitabine+Carboplatin, Paclitaxel+Carboplatin, Pemetrexed+Carboplatin | Intervention Type: DRUG; Name: Pemetrexed; Assigned to Arm(s): Paclitaxel+Carboplatin, Pemetrexed+Carboplatin, Pemetrexed+Cisplatin | Intervention Type: DRUG; Name: Cisplatin; Assigned to Arm(s): Gemcitabine+Cisplatin, Pemetrexed+Cisplatin | Intervention Type: DRUG; Name: Gemcitabine; Assigned to Arm(s): Gemcitabine+Carboplatin, Gemcitabine+Cisplatin

Answer: B