Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Intermittent Preventive Treatment With Sulfadoxine/Pyrimethamine During Pregnancy Among HIV-Positive and HIV-Negative Women: 2-Dose Versus Monthly - Malawi
Brief Summary: In Malawi, the standard of care to prevent malaria during pregnancy at the time of the study was a two dose sulfadoxine-pyrimethamine intermittent protective treatment (SP IPT) regimen administered in the second and third trimester of pregnancy. In this investigation, this two dose strategy was compared to a monthly SP regimen. The objective for the study was to determine the efficacy of the different regimens for HIV positive and HIV negative women in the prevention of placental malaria.


Options:
A: Intervention Type: DRUG; Name: Monthly sulfadoxine/pyrimethamine; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: 2-dose sulfadoxine/pyrimethamine; Assigned to Arm(s): N/A
B: Arm Label: IPTp-DHA-PPQ; Type: EXPERIMENTAL; Interventions: Drug: Dihydroartemisinin-piperaquine (DHA-PPQ) | Arm Label: IPTp-Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo Oral Tablet | Intervention Type: DRUG; Name: Dihydroartemisinin-piperaquine (DHA-PPQ); Assigned to Arm(s): IPTp-DHA-PPQ | Intervention Type: DRUG; Name: Placebo Oral Tablet; Assigned to Arm(s): IPTp-Placebo
C: Arm Label: 3 dose SP pregnancy / 3 monthly DP infancy; Type: ACTIVE_COMPARATOR; Interventions: Drug: 3 dose sulfadoxine-pyrimethamine (SP) for adult women during pregnancy, Drug: 3-monthly dihydroartemisinin-piperaquine (DP) for infants | Arm Label: 3 dose DP pregnancy / 3 monthly DP infancy; Type: ACTIVE_COMPARATOR; Interventions: Drug: 3 dose dihydroartemisinin-piperaquine (DP) for adult women during pregnancy, Drug: 3-monthly dihydroartemisinin-piperaquine (DP) for infants | Arm Label: 3 dose DP pregnancy / monthly DP infancy; Type: ACTIVE_COMPARATOR; Interventions: Drug: 3 dose dihydroartemisinin-piperaquine (DP) for adult women during pregnancy, Drug: Monthly dihydroartemisinin-piperaquine (DP) for infants | Arm Label: monthly DP pregnancy / 3 monthly DP infancy; Type: ACTIVE_COMPARATOR; Interventions: Drug: Monthly dihydroartemisinin-piperaquine (DP) for adult women during pregnancy, Drug: 3-monthly dihydroartemisinin-piperaquine (DP) for infants | Arm Label: monthly DP pregnancy / monthly DP infancy; Type: ACTIVE_COMPARATOR; Interventions: Drug: Monthly dihydroartemisinin-piperaquine (DP) for adult women during pregnancy, Drug: Monthly dihydroartemisinin-piperaquine (DP) for infants | Intervention Type: DRUG; Name: Monthly dihydroartemisinin-piperaquine (DP) for adult women during pregnancy; Assigned to Arm(s): monthly DP pregnancy / 3 monthly DP infancy, monthly DP pregnancy / monthly DP infancy | Intervention Type: DRUG; Name: 3 dose dihydroartemisinin-piperaquine (DP) for adult women during pregnancy; Assigned to Arm(s): 3 dose DP pregnancy / 3 monthly DP infancy, 3 dose DP pregnancy / monthly DP infancy | Intervention Type: DRUG; Name: 3 dose sulfadoxine-pyrimethamine (SP) for adult women during pregnancy; Assigned to Arm(s): 3 dose SP pregnancy / 3 monthly DP infancy | Intervention Type: DRUG; Name: Monthly dihydroartemisinin-piperaquine (DP) for infants; Assigned to Arm(s): 3 dose DP pregnancy / monthly DP infancy, monthly DP pregnancy / monthly DP infancy | Intervention Type: DRUG; Name: 3-monthly dihydroartemisinin-piperaquine (DP) for infants; Assigned to Arm(s): 3 dose DP pregnancy / 3 monthly DP infancy, 3 dose SP pregnancy / 3 monthly DP infancy, monthly DP pregnancy / 3 monthly DP infancy
D: Arm Label: IPTp-DP; Type: EXPERIMENTAL; Interventions: Drug: IPTp-DP | Arm Label: ISTp-DP; Type: EXPERIMENTAL; Interventions: Drug: ISTp-DP | Arm Label: IPTp-SP; Type: ACTIVE_COMPARATOR; Interventions: Drug: IPTp-SP | Intervention Type: DRUG; Name: IPTp-SP; Assigned to Arm(s): IPTp-SP | Intervention Type: DRUG; Name: IPTp-DP; Assigned to Arm(s): IPTp-DP | Intervention Type: DRUG; Name: ISTp-DP; Assigned to Arm(s): ISTp-DP

Answer: A