Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomised, Double-blind, Parallel Group Study to Assess the Efficacy and Safety of 52 Weeks of Once Daily Treatment of Orally Inhaled Tiotropium + Olodaterol Fixed Dose Combination (2.5 µg / 5 µg; 5 µg / 5 µg) (Delivered by the Respimat® Inhaler) Compared With the Individual Components (2.5 µg and 5 µg Tiotropium, 5 µg Olodaterol) (Delivered by the Respimat® Inhaler) in Patients With Chronic Obstructive Pulmonary Disease (COPD). [TOnado TM 1]
Brief Summary: The overall objective of this study is to assess the efficacy and safety of 52 weeks once daily treatment with orally inhaled tiotropium + olodaterol FDC (delivered by the RESPIMAT Inhaler) compared with the individual components ( tiotropium, olodaterol) (delivered by the RESPIMAT Inhaler) in patients with Chronic Obstructive Pulmonary Disease (COPD).


Options:
A: Arm Label: placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo to tiotropium + olodaterol | Arm Label: tiotropium + olodaterol high dose with BM; Type: EXPERIMENTAL; Interventions: Drug: tiotropium +olodaterol | Arm Label: tiotropium; Type: ACTIVE_COMPARATOR; Interventions: Drug: tiotropium | Arm Label: tiotropium + olodaterol with exercise training and BM; Type: EXPERIMENTAL; Interventions: Drug: tiotropium+olodaterol | Intervention Type: DRUG; Name: placebo to tiotropium + olodaterol; Assigned to Arm(s): placebo | Intervention Type: DRUG; Name: tiotropium+olodaterol; Assigned to Arm(s): tiotropium + olodaterol with exercise training and BM | Intervention Type: DRUG; Name: tiotropium +olodaterol; Assigned to Arm(s): tiotropium + olodaterol high dose with BM | Intervention Type: DRUG; Name: tiotropium; Assigned to Arm(s): tiotropium
B: Arm Label: Olodaterol and Tiotropium; Type: EXPERIMENTAL; Interventions: Drug: Olodaterol, Drug: Tiotropium | Arm Label: Placebo and Tiotropium; Type: OTHER; Interventions: Drug: Tiotropium, Drug: Placebo matching Olodaterol | Intervention Type: DRUG; Name: Tiotropium; Assigned to Arm(s): Placebo and Tiotropium | Intervention Type: DRUG; Name: Placebo matching Olodaterol; Assigned to Arm(s): Placebo and Tiotropium | Intervention Type: DRUG; Name: Olodaterol; Assigned to Arm(s): Olodaterol and Tiotropium | Intervention Type: DRUG; Name: Tiotropium; Assigned to Arm(s): Olodaterol and Tiotropium
C: Arm Label: tiotropium+olodaterol low dose FDC; Type: EXPERIMENTAL; Interventions: Drug: tiotropium + olodaterol, Device: Respimat | Arm Label: tiotropium+olodaterol high dose FDC; Type: EXPERIMENTAL; Interventions: Drug: tiotropium + olodaterol, Device: Respimat | Arm Label: olodaterol; Type: ACTIVE_COMPARATOR; Interventions: Drug: olodaterol, Device: Respimat | Arm Label: tiotropium low dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: tiotropium, Device: Respimat | Arm Label: tiotropium high dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: tiotropium, Device: Respimat | Intervention Type: DRUG; Name: tiotropium + olodaterol; Assigned to Arm(s): tiotropium+olodaterol low dose FDC | Intervention Type: DRUG; Name: tiotropium; Assigned to Arm(s): tiotropium low dose | Intervention Type: DRUG; Name: olodaterol; Assigned to Arm(s): olodaterol | Intervention Type: DRUG; Name: tiotropium; Assigned to Arm(s): tiotropium high dose | Intervention Type: DRUG; Name: tiotropium + olodaterol; Assigned to Arm(s): tiotropium+olodaterol high dose FDC | Intervention Type: DEVICE; Name: Respimat; Assigned to Arm(s): olodaterol, tiotropium high dose, tiotropium low dose, tiotropium+olodaterol high dose FDC, tiotropium+olodaterol low dose FDC
D: Arm Label: GFF MDI (PT003); Type: EXPERIMENTAL; Interventions: Drug: GFF MDI (PT003) | Arm Label: Placebo MDI; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo MDI | Intervention Type: DRUG; Name: GFF MDI (PT003); Assigned to Arm(s): GFF MDI (PT003) | Intervention Type: DRUG; Name: Placebo MDI; Assigned to Arm(s): Placebo MDI

Answer: C