TrialPanorama/Dataset huggingface dataset:
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Stroke - 65 Plus. Continued Active Life. A Randomised Controlled Trial of the Effect of a Novel Self-management Intervention Supporting Older Adults After Stroke
Brief Summary: Since august 2016, the researchers at a highly specialized neurorehabilitation hospital in a Danish region with 1.2 inhabitants have in cooperation with health professionals from a specialized neurorehabilitation in a Danish municipality with 336,000 inhabitants, worked through and is still working with an iterative process in the development of a novel self-management support intervention for elderly stroke individuals.The intervention is going to be implemented into the second phase- a randomized clinical controlled trial (RCT) in the project named 'Stroke - 65 plus. Continued active life'.


Options:
A: Inclusion Criteria:

* stroke survivors with rehabilitation needs discharge from rehabilitation hospital to home

Exclusion Criteria:

* do not understand danish Montreal Cognitive assessment (MOCA) below 20
B: Inclusion Criteria:

1. Ischemic or hemorrhagic stroke occurring at least 6 months prior to enrollment
2. MMSE score ≥ 19,MoCA\<26,able to follow the study instruction
3. Self- or informant-reported memory or cognitive complaints or CDR scale ≤ 0.5
4. Adequate cardiopulmonary function to perform aerobic exercise
5. Able to walk with or without assistive devices

Exclusion Criteria:

1. Unstable medical history (e.g., recent myocardial infarction) that might limit participation
2. Concomitant with other neurological disorders (e.g., Parkinson's disease, amyotrophic lateral sclerosis, multiple sclerosis)
3. Current participation in another interventional trial
C: Inclusion Criteria:

* age between 18-90 years old
* hemisyndrome (central paralysis of the upper extremity, and all degrees of weakness: M0 - M5 on the paresis scale) as a result of a first stroke
* sub-acute lesion not more than 6 weeks post ictus

Exclusion Criteria:

* insufficient state of consciousness
* severe aphasia
* severe cognitive deficits
* severe pathologies of the upper extremity of traumatic or rheumatic nature
* severe pain in the affected arm
* Patients with pacemakers and other active implants
D: Inclusion Criteria:

* patient at REHAB Basel
* brain-injury
* willing to participate in animal-assisted therapies
* physical and psychological resilience and ability to go/be transported outside to the "Therapie-Tiergarten"
* ability to get in contact with the animal autonomously

Exclusion Criteria:

* medical contraindications:allergies, phobias, etc.
* no willingness to participate in animal-assisted therapies
* patient might present a danger to the animals (aggressive behaviour)
* patient's medication changes radically during the time of data collection

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Treatment of Cervical Syndrome With Myofascial Therapies
Brief Summary: This study aimed to investigate the effects of myofascial release therapy (MRT) for improving pressure pain thresholds (PPTs), range of motion and pain in patients with mechanical neck pain (NP).


Options:
A: Inclusion Criteria:

* age between 18 and 75
* permanent neck pain for at least three months in a row
* a minimum of 40mm of neck pain on a 100mm visual analogue scale (VAS)
* having been in treatment to an orthopaedic or to a neurologist

Exclusion Criteria:

* neck pain caused by trauma, inflammatory or malignant disease, by congenital malformation of the spine or if pain was accompanied by radicular symptoms such as radiating pain, paresis, prickling or tingling.
* invasive treatments within the last 4 weeks, surgery to the spine within the last year, corticosteroid or opioid treatment.
* serious acute or chronic organic disease such as diabetes or cancer, mental disorders, pregnancy, and haemorrhagic tendency or anticoagulation treatment.
* non steroidal pain medication and physiotherapy were allowed if the treatment regimen was not altered for four weeks before and continued during the study.
B: Inclusion Criteria:

* Symptoms consistent with non-specific, uncomplicated neck pain of at least moderate level of pain
* Lives or works within Greater Seattle WA geographic area

Exclusion Criteria:

* Cervical Radiculopathy
* History of cancer (other than nonmelanoma skin cancer)
* Severe disk problems
* Unstable medical conditions
* Previous neck surgery
* Physically unable to get on and off of a massage table
* Has had massage within the last year
* Currently in litigation for neck pain
* Seeking other treatment for neck pain
* Potential contraindications for massage
* Unable to give informed consent
C: Inclusion Criteria:

* Patients of both sexes, aged between 20 and 60 years, in an active state of pain and diagnosed with muscle breakdown

Exclusion Criteria:

- Patients who are pregnant, have pacemakers and surgically operated in the area to be treated
D: Inclusion Criteria:

* Diagnosis of chronic mechanical neck pain.
* Flexion-rotation test positive (less of 32 degrees or 10 degrees difference between the two sides)
* Sign the informed consent form.

Exclusion Criteria:

* Presenting one or more positive safety cervical test .
* Carriers of pacemaker or defibrillators.
* Previous history of severe trauma to the cervical region of the spine.
* Inflammatory arthritis.
* Inability to maintain supine position.
* Inability to tolerate flexion-rotation test
* Poor Language and communication skills making difficult to understand the informed consent.
* Pending litigation or legal claim.

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: iLook Out for Child Abuse: An Innovative Learning Module for Childcare Providers
Brief Summary: This five-year study aims to improve childcare provider (CCP) reporting of suspected child abuse by means of an online learning module, iLook Out for Child Abuse. Using an interactive, video-based story-line (along with follow-up activities), iLookOut engages CCPs emotionally and intellectually to take the first step in addressing the epidemic of child abuse -which in the U.S. claims \>680,000 confirmed victims annually. The consequences of child abuse can be devastating and long-lasting. The purpose of this study is to establish an evidence-based intervention that can help those who care for young children recognize and report suspected child abuse before irreparable harm occurs.


Options:
A: Inclusion Criteria:

* Paid or volunteer staff at childcare facility

Exclusion Criteria:

* Younger than 18 years of age
B: Inclusion Criteria:

* Dental Interns enrolled in the Pediatric Dentistry and Dental Public Health Department, Faculty of Dentistry, Cairo University
* Participants of both genders
* Graduates of any dental school in Egypt

Exclusion Criteria:

* Participants who refused to sign the consent
* Participants who won't be able to have online access to the material
C: Inclusion Criteria:

* Works or volunteers at a childcare facility in Maine (i.e., home-based childcare, childcare center, Head Start facility, nursery school, pre-school)
* 18 years of age or older

Exclusion Criteria:

* Does not work or volunteer at a childcare facility in Maine
* Under 18 years of age
D: Inclusion Criteria:

* Working at the A\&E department of the UMC-Utrecht.

Exclusion Criteria:

* Absent during one of the two measurement periods.

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: System-integrated Technology-enabled Model of Care to Improve the Health of Stroke Patients in Rural China
Brief Summary: Despite the significant burden of stroke in rural China, secondary prevention of stroke is scarce. The aim of the study is to develop a system-integrated technology-enabled intervention (SINEMA) model for the secondary prevention of stroke in rural China and evaluate the effectiveness of the model compared with usual care. The hypothesis is that trained village doctors, equipped with digital health technology, can provide essential evidence-based care to stroke survivors in rural China.


Options:
A: Inclusion Criteria:

* Adults aged 30 yrs+ diagnosed with hypertension and /or diabetes who are able to give written consent (or verbal witnessed consent for illiterate patients).

Exclusion Criteria:

1. Patient requiring immediate referral to tertiary care due to accelerated hypertension, diabetic complications.
2. Patients with learning difficulties or vision/ hearing impairments but without a care giver making it impossible to use mobile phone.
3. Pregnant and lactating women.
B: Inclusion Criteria:

* the patient in the primary health care center

Exclusion Criteria:

* patients outside the research regions
C: Inclusion Criteria: those who

* are aged more than 18 years old;
* have a history of stroke (including ischemic and hemorrhagic stroke) diagnosed at county hospital or higher-level facilities, and currently in a clinically stable condition and not receiving acute stroke treatment;
* will live in this village for at least nine months during the next 12 months;
* have a basic communication ability (i.e. can understand simple instructions);
* give participant informed consent and are willing to participate in the study.

Exclusion Criteria: those who

* are unable to get out of bed without maximum assistance;
* have serious life-threatening disease such as cancers;
* who have an expected life span of less than 6 months.
D: Inclusion Criteria:

* District location in the Eastern region of Ghana.
* The districts should have an expected deliveries of ≥ 1,100 / year
* The District Health Management Team and the District Hospital Management Team must agree to participate in the study.

Exclusion Criteria:

* District location outside the Eastern region.
* The districts expected deliveries of \<1,100 / year
* The District Health Management Team and the District Hospital Management Team disagreeing to participate in the study.

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: System-integrated Technology-enabled Model of Care to Improve the Health of Stroke Patients in Rural China
Brief Summary: Despite the significant burden of stroke in rural China, secondary prevention of stroke is scarce. The aim of the study is to develop a system-integrated technology-enabled intervention (SINEMA) model for the secondary prevention of stroke in rural China and evaluate the effectiveness of the model compared with usual care. The hypothesis is that trained village doctors, equipped with digital health technology, can provide essential evidence-based care to stroke survivors in rural China.


Options:
A: Inclusion Criteria:

* diabetic, at least 18 years old, patient at a participating health clinic
B: Inclusion Criteria: those who

* are aged more than 18 years old;
* have a history of stroke (including ischemic and hemorrhagic stroke) diagnosed at county hospital or higher-level facilities, and currently in a clinically stable condition and not receiving acute stroke treatment;
* will live in this village for at least nine months during the next 12 months;
* have a basic communication ability (i.e. can understand simple instructions);
* give participant informed consent and are willing to participate in the study.

Exclusion Criteria: those who

* are unable to get out of bed without maximum assistance;
* have serious life-threatening disease such as cancers;
* who have an expected life span of less than 6 months.
C: Inclusion Criteria:

* individuals with diagnosis of Coronary Artery Disease (CAD) in Canadian Cardiovascular Society (CCS)'s functional classification of angina Class I or II
* patients who did not submit hospitalization for cardiovascular disease in the last year

Exclusion Criteria:

* patients who were not followed up in the health service to at least one year
* unstable patients requiring adjustments of medications or who are performing some diagnostic evaluation at discharge outpatient
D: Inclusion Criteria:

* Patients with a single non-emergent skin condition being referred to a VA Dermatology Clinic
* Must be a veteran at the study site

Exclusion Criteria:

* Full body examination requested
* Unable to read or speak English
* Emergent skin condition
* Pending dermatology appointment within 9 months
* Previous enrollment in the study
* Impending move from the area

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Chamas for Change: Validating an Integrated Community-based Strategy of Peer Support in Pregnancy and Infancy in Kenya
Brief Summary: This team has shown that chamas can be tailored to increase the uptake of health services in pregnancy and infancy, sustain themselves beyond the period of funding and become integrated within a county's health strategy. However, further investment is warranted to validate this intervention in a new region to ensure the positive effects on MNCH are a result of chamas and can be replicated. The purpose of this study is to demonstrate that chamas are an effective service-delivery platform for improving women's and children's health and well-being in western Kenya.


Options:
A: Inclusion Criteria:

* consenting pregnant clients, 20-40 weeks pregnant
* at least 18 years of age
* living within the catchment areas of the 84 mentor-mother CHWs taking part in this study
* enrolled in the Philani Mentor Mother Outreach Program

Exclusion Criteria:

* non-pregnant
* younger than 18 years of age
B: Inclusion Criteria:

* Pregnant; at least 28 weeks gestation
* HIV negative
* Daily access to a mobile phone
* Planning to stay in area for 6 months postpartum
* Able to read/write or has trusted person to help

Exclusion Criteria:

* Does not meet above criteria
C: Inclusion Criteria:

* Pregnant women \< 28 weeks, and their newborn infants following birth

Exclusion Criteria:

-
D: Note that this evaluation used administrative data - no participants were enrolled for the main part of this study. Participants were enrolled for the qualitative portions of the study.

Inclusion Criteria:

* Mothers who had an infant within the past 18 months during the intervention period (Oct 2013 - Mar 2014)
* Infants who were at least six weeks of age and under six months of age during the intervention period (Oct 2013 - Mar 2014)
* Qualitative activities included facility staff and mothers and caregivers whose infants were due for their 6 week immunization during the intervention period.

Exclusion Criteria:

* Mothers who did not have an infant within the past 18 months during the intervention period
* Infants who were less than six weeks of age during the intervention period or greater than six months of age throughout out the intervention period.
* Adults who were not mothers or caregivers with an infant due for his/her 6 week immunization during the intervention period were excluded from the qualitative activities.

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Respiratory Muscle Training in Patients With Cystic Fibrosis
Brief Summary: The present study aims at evaluating the effect of respiratory muscle training in adult patients with cystic fibrosis on lung function, exercise performance and quality of life.


Options:
A: Inclusion Criteria:

* In good health
* Living a sedentary lifestyle
B: Inclusion Criteria:

1. Male or female patients with a documented diagnosis of CF aged ≥18 years.
2. Written informed consent.
3. At least day 10 - 14 of IV antibiotic therapy during a hospital admission for a pulmonary exacerbation.
4. Patients must be able to perform acceptable spirometric manoeuvres, according to the American Thoracic Society/ERS (ATS/ERS) standards (Miller, Hankinson et. al. 2005).
5. Patient with an FEV1% predicted of ≥ 40%predicted (Stanojevic, Wade et al. 2008).
6. Patients who are productive of sputum from screening visit to study visit 1 (≥10g over 24 hours).
7. Patients who have been prescribed HTS (Nebusal 7%) and have successfully completed a challenge test.
8. Any other chronic medication must have commenced therapy 4 weeks prior to screening and be willing to continue this therapy for the entire duration of the study.

Exclusion Criteria:

1. Day 1-9 of IV antibiotic therapy during a hospital admission.
2. Patients who are colonized with Burkholderia cepacia complex.
3. Patient who are HTS naive.
4. Patients who have an intolerance to HTS.
5. Patients who are currently participating in another study or have participated in another study with an investigational drug within one month of screening.
6. Clinically significant disease or medical condition other than CF or CF-related conditions that, in the opinion of the Investigator, would compromise the safety of the patient or the quality of the data.

   -
C: Inclusion Criteria:

* Patients with a clinical diagnosis of cystic fibrosis
* Patients in steady state

Exclusion Criteria:

* Patients during exacerbation
* Patients treated by oral corticotherapy (\>0.5 mg/kg/j during \>7 days) during the past 2 months
* Pregnant patients
D: Inclusion Criteria:

* Cystic fibrosis diagnosis
* Stable clinical condition (no exacerbation in last 4 weeks)

Exclusion Criteria:

* Documented diagnosis of vestibular, neurological or orthopedic disorders which may affect balance and mobility
* Subjects previously involved in exercise training or physiotherapy programs

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Evaluation of the Build Our Kids' Success (BOKS) Before-school Physical Activity Program
Brief Summary: BOKS, Build Our Kids' Success, is a before-school physical activity program that has been implemented in over 2,000 elementary and middle schools. Students participate in the program for 12 weeks, two or three mornings per week for about 1 hour per session. This study if a non-randomized control trial seeking to 1) examine the extent to which participation in the before-school BOKS program improves, health, well-being, and performance, and 2) compare the results of a two-day-per-week versus a three-day-per-week program.


Options:
A: Inclusion Criteria:

* Student of the New Haven School District--State of Connecticut
* Enrolled in 12 eligible schools participating in study
* Child between the ages of 9 and 14 or in grades 5-8 as of the fall of 2011
* Primary Language of communication is English

Exclusion Criteria:

* Not enrolled in one of 12 participating schools
* Not in target grade (5-8) as of the fall 2011
B: Inclusion Criteria:

grade of 1 to 5 in primary schools and grade of 6 to 8 and 10 to 11 in secondary schools.

Exclusion Criteria:

Suffering or any history of disabilities, cardiovascular diseases, asthma, metabolic diseases, etc.
C: Inclusion Criteria:

* Participating school
* Child age 5-14 years

Exclusion Criteria:

* No valid parental consent
* Missing group assignment
D: Inclusion Criteria:

* Elementary school students in K-3 grade in the Bronx, New York

Exclusion Criteria:

* Inability to participate in basic exercise program
* Students whose parents signed the opt-out letter

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: A Multi-Centre, Randomised, Open-Label, Controlled Trial Evaluating the Efficacy and Safety of Prophylactic Administration of Concizumab in Haemophilia A and B Patients With Inhibitors
Brief Summary: This trial is conducted in Africa, Asia, Europe and North America. The aim of the trial is to assess the efficacy of concizumab administered s.c. (subcutaneously, under the skin) once daily in preventing bleeding episodes in haemophilia A and B patients with inhibitors.


Options:
A: Key Inclusion Criteria:

* Severe hemophilia A defined as \<1 IU/dL (\<1%) endogenous FVIII
* Male \<12 years of age and weight ≥13 kg
* History of at least 50 documented prior exposure days to FVIII
* No current, or history of, inhibitor development to FVIII

Key Exclusion Criteria:

* Other coagulation disorders in addition to Hemophilia A
* History of anaphylaxis associated with any FVIII or IV immunoglobulin administration

NOTE: Other protocol-defined Inclusion/Exclusion criteria may apply.
B: Inclusion Criteria: - Informed consent obtained before any trial related activities. Trial related activities are any procedures that are carried out as part of the trial, including activities to determine the suitability for the trial - Male haemophilia A or B patients with inhibitors aged 18 years or older at the time of signing informed consent - Patients currently in need of treatment with bypassing agents Exclusion Criteria: - Known or suspected hypersensitivity to trial product(s) or related products - Known inherited or acquired bleeding disorder other than haemophilia - Ongoing or planned immune tolerance induction therapy or prophylaxis with FVIII or FIX
C: Inclusion Criteria:

* Males, age 18 to 65 years.
* Subjects with Severe Hemophilia A with a documented plasma FVIII level of \< 1%
* ≥ 150 exposure days with FVIII concentrate(s) as supported by medical records

Exclusion Criteria:

* Evidence of current or past inhibitor antibody:
* History of any congenital or acquired coagulation disorders other than hemophilia A.
* Platelet count \<75,000/mm\*3.
* Abnormal renal function (serum creatinine \>2 x the upper limit of the normal range).
* Active liver disease verified by medical history or persistently elevated alanine aminotransferase or aspartate aminotransferase \>5 x the upper limit of the normal range or severe liver disease as evidenced by, but not limited to any of the following: International Normalized Ratio \>1.4, hypoalbuminemia, portal vein hypertension including presence of otherwise unexplained splenomegaly and history of esophageal varices.
D: Inclusion Criteria:

* Diagnosed with hemophilia A
* factor level less than 2%

Exclusion Criteria:

* More than 2 bleeds into the same joint

Answer: B