TrialPanorama/Dataset huggingface dataset:
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Zahra Teymuri, Zahedan University of Medical Sciences
Brief Summary: The purpose of this study was to evaluate the effects of stabilization exercises on pain, disability and pelvic floor muscles function in patients with lumbopelvic pain.


Options:
A: Inclusion Criteria:

* Pregnant women who are at least in their 20th week of gestation, living in the city of Pelotas (Brazil), whose deliveries are due to 2015 and belonging to the 2015 Birth Cohort.

Exclusion Criteria:

* Hypertension
* Diabetes
* Preterm birth history
* Miscarriage history
* Heart disease
* In vitro fertilization
* Twin pregnancy
* Persistent bleeding
* Body mass index above 35kg/m2
* Heavy smokers (above 20 cigarettes/day)
* Active women (\>150 min/week of physical activity).
B: Inclusion Criteria:

* Primiparous women who have not participated in a structured exercise program, including significant amounts of walking for the past six months are eligible for the trial.
* Other inclusion criteria are ability to read, write and speak Norwegian, and to be within their first 24 weeks of pregnancy.

Exclusion Criteria:

* Severe heart disease
* Pregnancy induced hypertension
* History of more than two miscarriages
* Persistent bleeding after week 12 of gestation
* Poorly controlled thyroid disease
* Poorly controlled pre-eclampsia and/or other diseases that could interfere with participation (Artal and O'Toole, 2003)
* In addition, all women who live to far from the university to be able to attend weekly training groups will be ineligible
C: Inclusion Criteria:

* age more than 18 years old
* pain located between costal margin to gluteal fold with or without radiation to lower limbs
* onset of pain during pregnancy or after delivery
* history of delivery at least 3 months ago.

Exclusion Criteria:

* known chronic rheumatologic or Orthopedic disorders
* systemic locomotor disease
* history of fracture, neoplasm,intervertebral disk pathology or radiculopathy, spondylolysis or spondylolysthesis
* contraindication of exercises, heart disease, diabetes, thrombophlebitis, uncontrolled epilepsy
* ongoing pregnancy
* treatment with specific stabilisation exercise during previous 3 months.
D: Inclusion Criteria:

* Being healthy and able to exercise following American College of Obstetricians and Gynecologists (ACOG) guidelines
* Being able to communicate in spanish
* Giving birth at Hospital Universitario de Torrejón, Hospital Universitario de Puerta de Hierro or Hospital Universitario Severo Ochoa (Madrid)

Exclusion Criteria:

* Multiparity
* Obstetrician complications
* Being interested in the study after 18 weeks
* Not having availability to attend to the physical exercise program
* Younger than 18 years old
* Older than 45 years old

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Efficacy of Glycine Powder Air-Polishing Combined With Scaling and Root Planing in the Treatment of Periodontitis and Halitosis: A Randomized Clinical Study
Brief Summary: The aim of this clinical study was to evaluate the clinical efficacy of using perio flow adjunctively with mechanical instrumentation on periodontal parameters and halitosis.

Sixty patients who presented with 4-6-mm probing pocket depth (PPD) were recruited for the study. Patients were randomly assigned to glycine powder air-polishing (GPAP) or control groups. For both groups PPDscores were recorded at the baseline and 1 month. Volatile sulphur compound (VSC) values were measured by a halimeter at the baseline, immediately after treatment, and at 7 days, 14 days and 1 month.


Options:
A: Inclusion Criteria:

* Clinical diagnosis of oral malodor
* At least 20 functional teeth
* No systemic diseases
* No severe dental diseases

Exclusion Criteria:

* Habit of smoking and betel quid chewing
* Oral malodor by food and other craniofacial abnormalities
* Current use of any kind of mouthwash
B: Inclusion Criteria:

* Clinical diagnosis of oral malodor
* Rinsing the mouthwash

Exclusion Criteria:

* oral malodor caused by foods
C: Inclusion Criteria:

* In the present trial, patients who had at least three teeth with 4-6-mm periodontal pockets.

Exclusion Criteria:

* acute infectious oral lesions,
* furcation defects,
* using antibiotics for any reason in the last 4 weeks,
* periodontal treatment in the last 6 months and
* pregnant or lactating patients.
D: Inclusion Criteria:

* Clinical diagnosis of oral malodor

Exclusion Criteria:

* Oral malodor caused by foods

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Care Optimization Through Patient and Hospital Engagement Clinical Trial for Heart Failure (CONNECT-HF)
Brief Summary: CONNECT-HF is a large-scale, pragmatic, cluster-randomized clinical trial to evaluate the effect of a customized, multifaceted, health system-level quality-improvement (QI) program compared with usual care on heart failure (HF) outcomes and HF quality-of-care metrics.


Options:
A: Inclusion Criteria:

* Age ≥ 18 years
* Acute HF as a primary cause of hospitalization

  * Hospitalizations for acute HF will be determined by local clinician-investigators but should include the following:
  * Symptoms (eg, dyspnea, fatigue), signs (eg, elevated jugular venous pressure, peripheral edema), or laboratory/imaging evidence of HF (eg, pulmonary congestion on chest x-ray, elevated natriuretic peptide levels) during the hospitalization and
  * Treatments aimed at acute HF (eg, intravenous diuretics, vasodilators, or inotropes)
* LVEF ≤ 40% based on last local measurement using echocardiography, multigated acquisition scan, computed tomography (CT) scanning, magnetic resonance imaging, or ventricular angiography
* Planned discharge to home or other supported care facility where patients are individually responsible for medication management

Exclusion Criteria:

* Prior heart transplant or current/planned left ventricular assistance device
* Chronic kidney disease requiring dialysis
* Terminal illness other than HF, such as malignancy, or with a life expectancy of less than 1 year as determined by the enrolling clinician-investigator
* Unable to participate in longitudinal follow-up, such as plans to move outside the US in the following year
B: Inclusion Criteria:

Nicaragua - adolescents aged 13-18 living in the 33 town districts of Managua with a population number that varies between 1400 and 4500 inhabitants and with more than 50 % poor people.

Bolivia and Ecuador: Students from conveniently selected secondary schools in Cochabamba (Bolivia) and Cuenca (Ecuador).
C: Inclusion Criteria:

1. Parent or guardian of an infant who is 12 months of age or younger
2. Speaks English or Spanish
3. Is 18 years of age or older

Exclusion Criteria:

1. Has plans to move out of Los Angeles county within the next 12 months
2. Has plans to change the primary care location for the index child within the next 12 months.
3. Parent or guardian is an employee of one of the primary care clinics that are part of the study.
D: Inclusion Criteria:

* all adult patients presenting for chronic or wellness care at the study practices

Exclusion Criteria:

* Acute illness

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Ideal Sedation for Stroke Thrombectomy
Brief Summary: The Ideal Sedation for Stroke Thrombectomy (ISST) registry will answer the key questions whether sedation with intubation and paralytics is feasible and whether it delays the time to recanalization in comparison with conscious sedation alone. As a pilot registry, it is anticipated to enroll 40 acute stroke patients requiring mechanical thrombectomy over 12-18 months. Following enrollment, data will be collected prospectively from medical records and from patients' visits.


Options:
A: Inclusion Criteria: All patients with ischemic stroke who:

* are greater than 18 years of age
* considered to be a candidate for endovascular therapy by the London Health Sciences Stroke team
* presenting within the first 8 hours after symptom onset EXCEPT THOSE for whom general anesthesia is thought to be clearly indicated or contraindicated, by the attending anesthesiologist.

Exclusion Criteria:

* Patients in whom the attending anesthesiologist considered that there was a clear indication for either GA or sedation
B: Inclusion Criteria:

* Acute anterior circulation ischemic stroke (terminal portion of the internal carotid artery, middle cerebral artery), with indication for radiological mechanical thrombectomy assessed by the neurology / neuroradiology team
* Over 18 years of age
* Benefiting from an affiliation to the French Social Security system
* Patient or familly informed consent. In case of patient incapacity and no family present, and due to the emergency of the procedure, the patient may be included on the sole decision of the investigator (emergency procedure with subsequent differed consent).

Exclusion Criteria:

* Altered vigilance defined by score ≥ 2 at item 1a "level of consciousness" of the NIHSS score
* Altered previous autonomy, defined by a modified Rankin score (mRS)\> 1
* Acute ischemic stroke of posterior circulation or anterior cerebral artery
* Associated brain haemorrhage
* Pregnant or nursing women
* Patient under law protection
* Stroke complicating another acute illness or postoperative stroke.
C: Inclusion Criteria:

* Age ≥ 18 years
* Suitable for intra-arterial treatment for acute stroke up to 8 hours from onset of symptoms
* Clinical equipoise for best mode of sedation

Exclusion Criteria:

* Any known allergy to either proposed medication and its alternative
* Any patient that has been intubated prior to randomization
* Posterior circulation strokes
* Age ≤ 18
* Pregnant female
D: Inclusion Criteria:

* NIHSS\>10
* mRS=\<2
* groin puncture\<6hours from stroke onset
* occlusion of ICA, ICA-T, M1, M2

Exclusion Criteria:

* MRI contraindications
* GCS\<9
* intubated prior to arrival
* posterior circulation stroke
* allergy to anestetics

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Effects of Electronic Cigarette Smoking on the Arterial Wall and Endothelial Glycocalyx Properties of Smokers
Brief Summary: Electronic cigarette is proposed as a bridge to smoking cessation. In this study we examine its effects on aortic elasticity, glycocalyx integrity, and exhaled carbon monoxide (CO) concentration and platelet function, both acutely and after 1 month of use.


Options:
A: Inclusion Criteria:

Subjects must meet all of the following inclusion criteria to be eligible for enrolment into the study:

1. Able to comply with the study procedures
2. Male or female healthy smokers aged ≥19
3. Smoking at least 10 cigarettes a day
4. Smoking for at least one year
5. Not currently attempting to quit smoking or wishing to do so in the next 30 days (this will be verified at screening by the answer ''NO'' to both questions ''Do you intend to quit in the next 30 days?'' and ''Are you interested in taking part in one of our smoking cessation programs?'')
6. Female smokers not planning to become pregnant are using an acceptable form of contraception.

Exclusion Criteria:

The presence of any of the following will exclude a subject from study enrolment:

1. Use of smokeless tobacco, or any other tobacco products (including e-cigarettes, cigars, chewing tobacco, snus, etc.) within the last 3 months, at baseline and during the whole study.
2. Use of nicotine replacement therapy or other smoking cessation therapies within the last 3 months and at baseline.
3. Self-reported pregnancy, planned pregnancy or breastfeeding.
4. Tobacco industry employees and 1st degree relatives will be excluded in order to safeguard independence of the study

   -
B: Inclusion Criteria:

* Healthy male and female adolescents (12 - 16 years inclusive) with a total body weight greater than 30 kg who currently smoke an average of at least 3 cigarettes per day.

Exclusion Criteria:

* Male and female subjects with a positive urine drug screen and female subjects with a positive pregnancy test.
C: Inclusion Criteria:

* Active conventional cigarette smoker

Exclusion Criteria:

* Health condition adversely affected by smoking, history or presence of cardiovascular disease
D: Inclusion Criteria:

* daily smoker
* 5+ cigarettes per day for at least one year
* expired carbon monoxide level of 5+ ppm

Exclusion Criteria:

* current use of smoking cessation pharmacotherapies
* current or history of psychotic disorder
* current major depressive disorder
* history of suicidal ideation in the previous 3 months
* unstable medical condition
* pregnant, nursing, or planning to become pregnant
* planning to move from study area within 18 months

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Interventions to Promote Healthy Eating and Physical Activity in Lebanese School Children Targeting Overweight and Obesity.
Brief Summary: Evaluate the feasibility and effectiveness of a multi-component school-based intervention to promote healthy eating and physical activity with school children ages 9 to 11 years in Lebanon.


Options:
A: Inclusion Criteria:

* Schoolchildren
* Aged 9 to 11 years

Exclusion Criteria:

- no exclusion criteria
B: Inclusion Criteria:

* Schools must have at least one full classrooms for the 3rd year of preschool.
* The approval of boards of governors will be necessary to participate in the intervention and in the measurements at the beginning and end of academic year.
* Children's parents or legal representatives will sign an informed consent to participate.
* Children's parents will be invited to collaborate by filling in questionnaires with regard to family leisure habits, sleeping, eating and getting around town.

Exclusion Criteria:

* Children with severe Spanish language learning difficulties.
* Children with serious physical or mental disorders identified by parents or teachers that would impede participation in the programme's activities
* Children diagnoses of chronic disorders, such as heart disease, diabetes or asthma, which in the opinion of their paediatricians would prevent their participation in the programme's activities (MOVI-da10!).
C: Inclusion Criteria:

Child in pre-school class in schools in disadvantaged areas

Exclusion Criteria:

None
D: Inclusion Criteria:

* Healthy pupils of primary schools (5th grade) and secondary schools (10th grade)

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Influence of Manual Fascial Manipulation on the Function of the Pelvic Floor in Pregnant Women
Brief Summary: Pregnancy and vaginal delivery are considered as the main risk factors for damage to the pelvic floor. There are various ways to measure the strength of the pelvic floor and to evaluate functional problems. Manual mobilization of the pelvic floor is a well-known treatment modality, however, ample knowledge exists on the efficacy of physiotherapy and exercise for improvement of pelvic floor function and strength. The aim of this study is to analyze the influence of pelvic floor fascial mobilization (PFFM) technique on the function and strength of the pelvic floor muscles as well as parameters presumed to be influenced by the strength of the pelvic floor in pregnant women.


Options:
A: Inclusion Criteria:

* 58 consenting pregnant for the first time aged between 20 and 35 years, with no experience of urinary loss episodes before gestation will be assessed.

Exclusion Criteria:

* Women who had more than one previous pregnancy
B: Inclusion Criteria:

* complaints of urinary leakage \> 3 in last month (not stress incontinence)
* functionally independent subjects

Exclusion Criteria:

* urinary tract infection
* urogenital prolapse
* unstable diabetes
* neurological or psychiatric disease
* narrow angle glaucoma
* after colposuspension or sling surgery
* Mini Mental State Examination \<24
C: Inclusion criteria:

1. Age 20-45 years old
2. Gestational age 24-30 weeks gestation
3. Singleton pregnancy
4. Expected second-4ourth delivery

Exclusion criteria

1. First delivery
2. Gestational age at more than 30 weeks gestation at enrollment
3. Premature contractions
4. Cervical insufficiency
5. Placenta previa
6. Placenta accrete
7. Multifetal pregnancy
8. Maternal chronic illness including connective tissue disease, neurological illness
D: Inclusion Criteria:

* Being healthy and able to exercise following American College of Obstetricians and Gynecologists (ACOG) guidelines
* Being able to communicate in spanish
* Giving birth at Hospital Universitario de Fuenlabrada

Exclusion Criteria:

* Multiparity
* Obstetrician complications
* Being interested in the study after 18 weeks
* Not being regular in physical exercise program
* Younger than 18 years old

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Corneal Collagen Crosslinking to Increase the Resistance of the Graft Used as a Support for the Boston Keratoprosthesis Type I Against Corneal Melting
Brief Summary: The purpose of this study is to demonstrate the safety and efficacy of the corneal collagen crosslinking with riboflavin and ultraviolet A in aim to increase the resistance of the graft used as a support for the Boston keratoprosthesis (KPro) type I against corneal melting (keratolysis or sterile necrosis).


Options:
A: Inclusion Criteria:

* Candidate for KPro type I
* Capacity to give written consent
* Ability to be followed for the duration of the study

Exclusion Criteria:

* Participation in another interventional study
* Failure to wear a therapeutic contact lens due to abnormalities of the eyelids.
* Inability to give written consent

Contraindications to the KPro type I:

* Severe dryness with keratinization of the ocular surface
* Intraocular tumor
* Terminal glaucoma
* Inoperable retinal detachment
* Phthisis bulbi
B: Inclusion Criteria:

* 18 years of age or older
* A diagnosis of keratoconus or a diagnosis of corneal ectasia after corneal refractive surgery
* Vision with contact lenses or glasses is worse than 20/20
* Corneal thickness greater than 375 microns at the thinnest point

Exclusion Criteria:

* Eyes classified as either normal, atypical normal, or keratoconus suspect on the severity grading scheme.
* Corneal pachymetry ≤ 350 microns at the thinnest point measured by Pentacam in the eye(s) to be treated.
* Previous ocular condition (other than refractive error) in the eye(s) to be treated that may predispose the eye for future complications
* Clinically significant corneal scarring in the CXL treatment zone
* Pregnancy (including plan to become pregnant) or lactation during the course of the study
* A known sensitivity to study medications
* Patients with nystagmus or any other condition that would prevent a steady gaze during the CXL treatment or other diagnostic tests.
* Patients with a current condition that, in the investigator's opinion, would interfere with or prolong epithelial healing.
C: Inclusion Criteria:

* Ulcer size more than 5 mm
* Ulcer depth upto 70% of stromal depth
* Corneal thickness of 400 microns and above

Exclusion Criteria:

* Corneal thickness of below 400 microns
* Ulcers involving the limbus
* Pregnant women
* Children below the age of 18 years
D: Inclusion Criteria:

* fungal keratitis documented by culture or confocal scanning without any previous treatment

Exclusion Criteria:

* Previous treatment
* Thinning at presentation
* Perforation
* Associated with other microbial or viral keratitis

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Combined Mechanical and Oral Antibiotic Bowel Preparation Versus Oral Antibiotics Alone for the Reduction of Surgical Site Infection Following Elective Colorectal Resection
Brief Summary: This randomized clinical trial studies how well neomycin and metronidazole hydrochloride with or without polyethylene glycol work in reducing infection in patients undergoing elective colorectal surgery. Polyethylene glycol, may draw water from the body into the colon, flushing out the contents of the colon. Antibiotics, like neomycin and metronidazole hydrochloride, may stop bacteria from growing. It is not yet known whether it's better to give preoperative neomycin and metronidazole hydrochloride with or without polyethylene glycol in reducing surgical site infection after colorectal surgery.


Options:
A: Inclusion Criteria:

* undergoing elective colon surgery for benign or malignant disease
* over the age of 18 years
* provides informed consent.

Exclusion Criteria:

* known anaphylaxis to neomycin or metronidazole
* pregnancy or lactation
* chronic renal failure (serum creatinine \> 220 umol/L).
B: Inclusion Criteria:

* Patients undergoing ileocolic resections, partial and total colectomies, and rectal resections for neoplasm, inflammatory bowel disease, or diverticulitis
* Subjects with the mental capacity to give informed consent

Exclusion Criteria:

* Patients undergoing emergent colorectal resections
* Patients who are decisionally-impaired and lack the mental capacity to give informed consent
C: Inclusion Criteria:

The main inclusion criterion was elective colorectal surgery with primary anastomosis

Exclusion Criteria:

Exclusion criteria were an acute laparotomy, laparoscopic colorectal surgery, contraindications for the use of mechanical bowel preparation, an a priori deviating (ileo) stoma, and age less than 18 years old.
D: Inclusion Criteria:

* Age \> 18
* Laparoscopic or non-laparoscopic elective colorectal surgery

Exclusion Criteria:

* Non elective colorectal surgery (emergent surgery and/or reintervention or revision of a previous colorectal procedure)
* Significant concomitant surgical procedure (e.g., liver resection for metastasis)
* Bacterial infection at the time of surgery or antimicrobial therapy up to 2 weeks before surgery
* Inflammatory bowel disease
* Severe obesity (defined as a BMI \>35 kg/m2)
* Known history of hypersensitivity to β-lactams and imidazoles
* Preoperative severe impairment in renal function (creatinine clearance (MDRD) \< 30 ml/min)
* Patients with known colonization with multidrug-resistant digestive bacteria, especially multidrug-resistant gram-negative bacteria (requiring specific infection control measures)
* Allergy to lactose, galactose intolerance, Lapp lactase deficiency or glucose/galactose malabsorption (rare metabolic disease)
* Pregnant women, breastfeeding women, women of childbearing age without effective contraceptive- Refusal to participate or inability to provide informed consent

Answer: B