Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Operations and Pelvic Muscle Training in the Management of Apical Support Loss: The OPTIMAL Trial: A Randomized Trial of Sacrospinous Ligament Fixation (SSLF) Versus Uterosacral Ligament Suspension (ULS) With and Without Perioperative Behavioral Therapy/Pelvic Muscle Training
Brief Summary: Pelvic organ prolapse is common among women with a prevalence that has been estimated to be as high as 30%. Pelvic organ prolapse often involves a combination of support defects involving the anterior, posterior and/or apical vaginal segments. While the anterior vaginal wall is the segment most likely to demonstrate recurrent prolapse after reconstructive surgery, reoperations are highest among those who require apical suspension procedures with or without repair of other vaginal segments (12%-33%). Despite the substantial health impact, there is a paucity of high quality evidence to support different practices in the management of prolapse, particularly surgery. Thus, the objectives of the Operations and Pelvic Muscle Training in the Management of Apical Support Loss (OPTIMAL) Trial are:

1. to compare sacrospinous ligament fixation (SSLF) to uterosacral vaginal vault ligament suspension (ULS); and
2. to assess the role of perioperative behavioral therapy/pelvic muscle training (PMT) in women undergoing vaginal surgery for apical or uterine prolapse and stress urinary incontinence.


Options:
A: Arm Label: PFMT group; Type: ACTIVE_COMPARATOR; Interventions: Other: Exercises | Arm Label: HE + PFM group; Type: ACTIVE_COMPARATOR; Interventions: Other: Exercises | Arm Label: HE group; Type: ACTIVE_COMPARATOR; Interventions: Other: Exercises | Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Other: Exercises | Intervention Type: OTHER; Name: Exercises; Assigned to Arm(s): Control, HE + PFM group, HE group, PFMT group
B: Arm Label: Nitrofurantoin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nitrofurantoin | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Nitrofurantoin; Assigned to Arm(s): Nitrofurantoin | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
C: Arm Label: SSLF and PMT; Type: EXPERIMENTAL; Interventions: Procedure: SSLF, Behavioral: PMT | Arm Label: ULS and PMT; Type: EXPERIMENTAL; Interventions: Procedure: ULS, Behavioral: PMT | Arm Label: SSLF without PMT; Type: EXPERIMENTAL; Interventions: Procedure: SSLF | Arm Label: ULS without PMT; Type: EXPERIMENTAL; Interventions: Procedure: ULS | Intervention Type: PROCEDURE; Name: SSLF; Assigned to Arm(s): SSLF and PMT, SSLF without PMT | Intervention Type: PROCEDURE; Name: ULS; Assigned to Arm(s): ULS and PMT, ULS without PMT | Intervention Type: BEHAVIORAL; Name: PMT; Assigned to Arm(s): SSLF and PMT, ULS and PMT
D: Arm Label: Group A; Type: ACTIVE_COMPARATOR; Interventions: Other: No bowel prep | Arm Label: Group B; Type: ACTIVE_COMPARATOR; Interventions: Other: Clear liquid diet and 2 Fleet's enemas | Intervention Type: OTHER; Name: No bowel prep; Assigned to Arm(s): Group A | Intervention Type: OTHER; Name: Clear liquid diet and 2 Fleet's enemas; Assigned to Arm(s): Group B

Answer: C