Please select the eligibility criteria that correspond to the clinical trial below.
Title: Title: Comparative Effectiveness of Pedometer-Based Walking Interventions: WalkMore
Brief Summary: The WalkMore study will help find out how walking interventions can help overweight/obese postmenopausal women with increased risk of cardiovascular disease lower their blood pressure.


Options:
A: Inclusion Criteria:

* Have PAD
* Potential participants with a resting ABI greater than or equal to 0.91 and less than or equal to 1.00 at their baseline visit will be eligible if their ABI drops by at least 20% after the heel-rise test. Potential participants with a resting baseline ABI greater than 0.91 who do not meet criteria for inclusion based on the heel-rise test can be eligible if they have data from a certified non-invasive vascular laboratory that demonstrates presence of lower extremity ischemia. However, more evidence than an abnormal PVR from the non-invasive vascular laboratory is required (for example, a toe brachial index pressure less than 0.60). Finally, potential participants who do not meet the above criteria for inclusion will be eligible if they have an angiogram demonstrating greater than 50% stenosis on one or more lower extremity arterial vessels.

Exclusion Criteria:

* Below or above knee amputation
* Wheelchair confinement
* Uses a walking aid other than a cane (e.g., walker)
* Unable to return to the medical center at the required visit frequency
* Greater than Class II New York Heart Association heart failure or angina (symptoms at rest or with minimal exertion)
* Any increase in angina pectoris symptoms during the 6 months before study entry or angina at rest
* Presence of a foot ulcer
* Lower extremity revascularization or major orthopedic surgery during the 3 months before study entry
* Heart attack or coronary artery bypass grafting during the 3 months before study entry
* Major medical illnesses, including treatment for cancer (except non-melanoma skin cancer) during the 12 months before study entry
* Planned lower extremity revascularization within the 12 months after study entry
* Current participation in another clinical trial
* Walking for exercise at a level comparable to that targeted in the study's intervention
* Completion of a cardiac rehabilitation program within 3 months before study entry
* Coronary ischemia during exercise, defined as ST segment depression greater than 1 mm during the baseline exercise treadmill test, with or without associated chest discomfort
* Left-bundle branch block or significant ST-T wave changes on the baseline ECG without a perfusion stress test, demonstrating no reversible ischemia within the 3 months before study entry
* Stopping during the treadmill exercise stress test because of chest pain, shortness of breath, hip or knee arthritis. These individuals will be interviewed by the principal investigator and will be excluded only if it is determined that their walking performance (based in part on the treadmill test) is limited by a comorbidity other than leg ischemia.
* Unable to walk at least 50 feet without stopping during the 6-minute walk test
* Stopping during the 6-minute walk test for symptoms other than ischemic leg symptoms
* Mini-Mental Status Examination (MMSE) score of less than 23 or psychiatric illness
* Failure to complete a study run-in period
* Parkinson's disease
* Requires oxygen with exertion.
B: Inclusion Criteria:

* Woman between 45-74 years of age
* Have not had a menstrual period for at least 12 months
* Are not regularly physically active (self-reported non-exerciser for previous 6 months)
* Have a body mass index (BMI) between 25-45 kg/m2
* Have high normal blood pressure or (systolic pressure of 130-179 mmHg or a diastolic pressure of 85-99 mmHg)
* Not limited in your ability to walk
* Understand these criteria
* Are willing to provide informed consent
* Willing to be randomized to either type of walking intervention or a control group being studied, and are willing to follow the protocol for the group to which they have been assigned

Exclusion Criteria:

* Have a past history and/or physical examination or laboratory findings of a medical condition including (but not limited to):
* Have any medical condition or disease that is life-threatening or that can interfere with or be aggravated by exercise
* Have been diagnosed with diabetes
* Blood pressure is greater than 179 mmHg systolic or 99 mmHg diastolic.
* Participating in another research study which may effect the results of WalkMore
C: Inclusion Criteria:

* physically inactive, i.e. takes less than 8,000 steps per day at baseline
* registered at the participating general practice,
* over 18 years of age,
* regular email user, and willing to use email for the purpose of the study,
* has a home computer with access to the Internet.

Exclusion Criteria:

* medical or psychiatric condition which the general practitioner considers as inappropriate for participating in the intervention (e.g., terminal illness, psychotic illness, chronic disorders or diseases that seriously influence the ability to be physically active, dementia or significant cognitive impairment, unable to move about independently),
* medical, personal of family condition which the general practitioner considers temporarily affects mean daily step count at baseline (e.g., acute illness, holiday or business trip),
* pregnant woman,
* currently engaging in regular sports or exercise (at least twice a week),
* failure to upload pedometer data to a website at baseline assessment,
* failure to give informed consent with the study.
D: Inclusion Criteria:

* Full-time employees living in Singapore
* Aged between 21-65

Exclusion Criteria:

* report difficulty doing 10 minutes of aerobic activities without stopping
* report difficulty walking up 10 stairs without stopping
* report difficulty performing basic activities of daily living
* have any medical conditions that limit their ability to walk as a means of physical activity
* self-identify medical conditions that limit ability to walk AND do not have medical consent
* answer 'YES' to any PAR-Q questions

Answer: B