Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase III Randomised, Double-blind, Active-controlled Parallel Group Efficacy and Safety Study of BI 10773 Compared to Glimepiride Administered Orally During 104 Weeks With a 104 Week Extension Period in Patients With Type 2 Diabetes Mellitus and Insufficient Glycaemic Control Despite Metformin Treatment
Brief Summary: This is a pivotal phase III study, mandatory to seek approval by regulatory authorities for BI 10773 as an anti-diabetic agent compared to an active comparator in patients with type 2 diabetes mellitus and insufficient glycaemic control.


Options:
A: Arm Label: metformin + glimepiride + pioglitazone + albiglutide placebo; Type: ACTIVE_COMPARATOR; Interventions: Drug: placebo to match albiglutide, Drug: metformin, Drug: glimepiride, Drug: pioglitazone | Arm Label: metformin + glimepiride + pioglitazone placebo + albiglutide; Type: EXPERIMENTAL; Interventions: Biological: albiglutide, Drug: metformin, Drug: glimepiride, Drug: placebo to match pioglitazone | Arm Label: met + glimepiride + pioglitazone placebo + albiglutide placebo; Type: ACTIVE_COMPARATOR; Interventions: Drug: placebo to match albiglutide, Drug: metformin, Drug: glimepiride, Drug: placebo to match pioglitazone | Intervention Type: DRUG; Name: placebo to match albiglutide; Assigned to Arm(s): met + glimepiride + pioglitazone placebo + albiglutide placebo, metformin + glimepiride + pioglitazone + albiglutide placebo | Intervention Type: BIOLOGICAL; Name: albiglutide; Assigned to Arm(s): metformin + glimepiride + pioglitazone placebo + albiglutide | Intervention Type: DRUG; Name: metformin; Assigned to Arm(s): met + glimepiride + pioglitazone placebo + albiglutide placebo, metformin + glimepiride + pioglitazone + albiglutide placebo, metformin + glimepiride + pioglitazone placebo + albiglutide | Intervention Type: DRUG; Name: glimepiride; Assigned to Arm(s): met + glimepiride + pioglitazone placebo + albiglutide placebo, metformin + glimepiride + pioglitazone + albiglutide placebo, metformin + glimepiride + pioglitazone placebo + albiglutide | Intervention Type: DRUG; Name: pioglitazone; Assigned to Arm(s): metformin + glimepiride + pioglitazone + albiglutide placebo | Intervention Type: DRUG; Name: placebo to match pioglitazone; Assigned to Arm(s): met + glimepiride + pioglitazone placebo + albiglutide placebo, metformin + glimepiride + pioglitazone placebo + albiglutide
B: Arm Label: Canagliflozin 300 mg; Type: EXPERIMENTAL; Interventions: Drug: Canagliflozin 300 mg, Drug: Metformin, Drug: Sulphonylurea | Arm Label: Sitagliptin 100 mg; Type: ACTIVE_COMPARATOR; Interventions: Drug: Sitagliptin 100 mg, Drug: Metformin, Drug: Sulphonylurea | Intervention Type: DRUG; Name: Sitagliptin 100 mg; Assigned to Arm(s): Sitagliptin 100 mg | Intervention Type: DRUG; Name: Canagliflozin 300 mg; Assigned to Arm(s): Canagliflozin 300 mg | Intervention Type: DRUG; Name: Metformin; Assigned to Arm(s): Canagliflozin 300 mg, Sitagliptin 100 mg | Intervention Type: DRUG; Name: Sulphonylurea; Assigned to Arm(s): Canagliflozin 300 mg, Sitagliptin 100 mg
C: Arm Label: Liraglutide; Type: EXPERIMENTAL; Interventions: Drug: liraglutide | Arm Label: Exenatide; Type: ACTIVE_COMPARATOR; Interventions: Drug: exenatide | Intervention Type: DRUG; Name: liraglutide; Assigned to Arm(s): Liraglutide | Intervention Type: DRUG; Name: exenatide; Assigned to Arm(s): Exenatide
D: Arm Label: BI 10773 dose plus metformin; Type: EXPERIMENTAL; Interventions: Drug: BI 10773, Drug: Placebo | Arm Label: Glimepiride 1-4 mg plus metformin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Glimepiride, Drug: Placebo | Intervention Type: DRUG; Name: BI 10773; Assigned to Arm(s): BI 10773 dose plus metformin | Intervention Type: DRUG; Name: Glimepiride; Assigned to Arm(s): Glimepiride 1-4 mg plus metformin | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Glimepiride 1-4 mg plus metformin | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): BI 10773 dose plus metformin

Answer: D