Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Prospective Randomized Comparison of ABVD Versus BEACOPP Chemotherapy With or Without Radiotherapy for Advanced Stage or Unfavorable Hodgkin's Lymphoma (HL)
Brief Summary: The choice of a preferred first-line treatment requires balancing the desire for optimal disease control with the occurrence of early and late treatment-related effects. To fully assess this balance, the treatment decision process should ideally take into account the outcome following a consistent second-line therapy, in particular when tolerated, widely applicable and highly effective salvage regimens exist, like in Hodgkin lymphoma failing initial chemotherapy.


Options:
A: Arm Label: Arm B; Type: EXPERIMENTAL; Interventions: Drug: Bleomycin, Drug: Etoposide, Drug: Doxorubicin, Drug: Cyclophosphamide, Drug: Vincristine, Drug: Procarbazine, Drug: Prednisone | Arm Label: Arm A; Type: ACTIVE_COMPARATOR; Interventions: Drug: Doxorubicin, Drug: Bleomycin, Drug: Vinblastine, Drug: Dacarbazine | Intervention Type: DRUG; Name: Bleomycin; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Etoposide; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Doxorubicin; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Cyclophosphamide; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Vincristine; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Procarbazine; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Prednisone; Assigned to Arm(s): Arm B | Intervention Type: DRUG; Name: Doxorubicin; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: Bleomycin; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: Vinblastine; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: Dacarbazine; Assigned to Arm(s): Arm A
B: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Drug: BEACOPP escalated | Arm Label: B; Type: EXPERIMENTAL; Interventions: Drug: Rituximab, Drug: BEACOPP escalated | Arm Label: C; Type: ACTIVE_COMPARATOR; Interventions: Drug: BEACOPP escalated | Arm Label: D; Type: EXPERIMENTAL; Interventions: Drug: BEACOPP escalated | Intervention Type: DRUG; Name: Rituximab; Assigned to Arm(s): B | Intervention Type: DRUG; Name: BEACOPP escalated; Assigned to Arm(s): A, B, C, D
C: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Drug: Adriamycin, Drug: Bleomycin, Drug: Vinblastine, Drug: DTIC, Radiation: radiation therapy | Arm Label: C; Type: EXPERIMENTAL; Interventions: Drug: Adriamycin, Drug: Bleomycin, Drug: Etoposide, Drug: Procarbazine, Drug: Prednisone, Drug: Vincristine, Radiation: radiation therapy | Arm Label: B; Type: EXPERIMENTAL; Interventions: Drug: Adriamycin, Drug: Bleomycin, Drug: Vinblastine, Drug: DTIC, Radiation: radiation therapy | Arm Label: D; Type: EXPERIMENTAL; Interventions: Drug: Adriamycin, Drug: Bleomycin, Drug: Etoposide, Drug: Procarbazine, Drug: Prednisone, Drug: Vincristine, Radiation: radiation therapy | Intervention Type: DRUG; Name: Adriamycin; Assigned to Arm(s): A, B, C, D | Intervention Type: DRUG; Name: Bleomycin; Assigned to Arm(s): A, B, C, D | Intervention Type: DRUG; Name: Vinblastine; Assigned to Arm(s): A, B | Intervention Type: DRUG; Name: DTIC; Assigned to Arm(s): A, B | Intervention Type: DRUG; Name: Etoposide; Assigned to Arm(s): C, D | Intervention Type: DRUG; Name: Procarbazine; Assigned to Arm(s): C, D | Intervention Type: DRUG; Name: Prednisone; Assigned to Arm(s): C, D | Intervention Type: DRUG; Name: Vincristine; Assigned to Arm(s): C, D | Intervention Type: RADIATION; Name: radiation therapy; Assigned to Arm(s): A, B, C, D
D: Arm Label: Arm I; Type: ACTIVE_COMPARATOR; Interventions: Biological: bleomycin sulfate, Drug: dacarbazine, Drug: doxorubicin hydrochloride, Drug: vinblastine sulfate | Arm Label: Arm II; Type: ACTIVE_COMPARATOR; Interventions: Drug: dacarbazine, Drug: doxorubicin hydrochloride, Drug: vinblastine sulfate | Arm Label: BEACOPP-14 chemotherapy; Type: EXPERIMENTAL; Interventions: Biological: bleomycin sulfate, Biological: filgrastim, Biological: pegfilgrastim, Drug: cyclophosphamide, Drug: doxorubicin hydrochloride, Drug: etoposide, Drug: prednisolone, Drug: procarbazine hydrochloride, Drug: vincristine sulfate | Arm Label: BEACOPP-escalated chemotherapy; Type: EXPERIMENTAL; Interventions: Biological: bleomycin sulfate, Biological: filgrastim, Biological: pegfilgrastim, Drug: cyclophosphamide, Drug: doxorubicin hydrochloride, Drug: etoposide, Drug: prednisolone, Drug: procarbazine hydrochloride, Drug: vincristine sulfate | Intervention Type: BIOLOGICAL; Name: bleomycin sulfate; Assigned to Arm(s): Arm I, BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: BIOLOGICAL; Name: filgrastim; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: BIOLOGICAL; Name: pegfilgrastim; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: cyclophosphamide; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: dacarbazine; Assigned to Arm(s): Arm I, Arm II | Intervention Type: DRUG; Name: doxorubicin hydrochloride; Assigned to Arm(s): Arm I, Arm II, BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: etoposide; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: prednisolone; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: procarbazine hydrochloride; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy | Intervention Type: DRUG; Name: vinblastine sulfate; Assigned to Arm(s): Arm I, Arm II | Intervention Type: DRUG; Name: vincristine sulfate; Assigned to Arm(s): BEACOPP-14 chemotherapy, BEACOPP-escalated chemotherapy

Answer: A