Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effects of Combined High Intensity Aerobic Interval Training Program and Mediterranean Diet Recommendations in Post-Myocardial Infarct Patients: INTERFARCT Controlled Trial
Brief Summary: Acute myocardial infarction (MI) continues remains to be a major cause of death and disability worldwide. Exercise therapy has long been used for rehabilitation purposes and the benefit of regular physical exercise is also well established. The intensity of aerobic exercise training is a key issue in cardiac rehabilitation programmes.Endurance aerobic training is typically performed as continuous training at moderate to-high exercise intensity in steady-state conditions of aerobic energetic yield. However, interval training (i.e., repeated bouts of short-duration, high to severe- or severe to extreme-intensity exercise, separated by brief periods of lower-intensity) has been proposed to be more effective than continuous exercise for improving exercise capacity. Adding to that, health-related adaptations to low-volume and high intensity interval training have been presented.

On the other hand, the Mediterranean Diet has been widely reported to be a model of healthy eating for its contribution to a favourable health status and a better quality of life, reducing in overall mortality from cardiovascular diseases.

Considering all the above mentioned in MI population, the principal objective for the INTERFARCT study will be to assess the effects of different programs of high intensity aerobic interval training and Mediterranean Diet recommendations in the clinical condition, cardio-respiratory fitness, biomarkers, ventricular function and perception of quality of life after myocardial infarction.

Methods/Design: One hundred and fifty people after suffering acute MI will perform different assessments to evaluate clinical history, physical, biochemical and nutritional condition, and quality of life before and after 16-week of follow-up. All participants will receive Mediterranean diet recommendations and will be randomly assigned to attention control group (diet and physical activity recommendations) or exercise groups (diet recommendations plus high-intensity aerobic interval exercise). Participants assigned to an exercise group will train 2 days/week under supervision (day 1-treadmill and day 2-bike protocol). There will be two aerobic exercise groups: 1) high-intensity interval training and high-volume (HV-HIIT) group, and 2) high-intensity interval training and low-volume (LV-HIIT) group.


Options:
A: Arm Label: Usual care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Usual care + letters; Type: EXPERIMENTAL; Interventions: Behavioral: Usual care + letters | Arm Label: Usual care + letters + automated calls; Type: EXPERIMENTAL; Interventions: Behavioral: Usual care + letters + automated calls | Intervention Type: BEHAVIORAL; Name: Usual care + letters; Assigned to Arm(s): Usual care + letters | Intervention Type: BEHAVIORAL; Name: Usual care + letters + automated calls; Assigned to Arm(s): Usual care + letters + automated calls
B: Arm Label: Weight Loss; Type: EXPERIMENTAL; Interventions: Other: Weight Loss | Arm Label: Interval Training; Type: EXPERIMENTAL; Interventions: Other: Interval Training | Intervention Type: OTHER; Name: Interval Training; Assigned to Arm(s): Interval Training | Intervention Type: OTHER; Name: Weight Loss; Assigned to Arm(s): Weight Loss
C: Arm Label: 12 week exercise training; Type: EXPERIMENTAL; Interventions: Behavioral: Structured exercise training | Arm Label: Conventional Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Structured exercise training; Assigned to Arm(s): 12 week exercise training
D: Arm Label: Attention Control Group (AC); Type: ACTIVE_COMPARATOR; Interventions: Other: Mediterranean Diet Recommendations, Other: Physical Activity Recommendations | Arm Label: HV-HIIT; Type: EXPERIMENTAL; Interventions: Other: HIGH VOLUME (HV) Supervised exercise, Other: Mediterranean Diet Recommendations | Arm Label: LV-HIIT; Type: EXPERIMENTAL; Interventions: Other: Mediterranean Diet Recommendations, Other: LOW VOLUME (LW) Supervised exercise | Intervention Type: OTHER; Name: HIGH VOLUME (HV) Supervised exercise; Assigned to Arm(s): HV-HIIT | Intervention Type: OTHER; Name: Mediterranean Diet Recommendations; Assigned to Arm(s): Attention Control Group (AC), HV-HIIT, LV-HIIT | Intervention Type: OTHER; Name: Physical Activity Recommendations; Assigned to Arm(s): Attention Control Group (AC) | Intervention Type: OTHER; Name: LOW VOLUME (LW) Supervised exercise; Assigned to Arm(s): LV-HIIT

Answer: D