TrialPanorama/Dataset huggingface dataset:
Please select the eligibility criteria that correspond to the clinical trial below.
Title: A Randomized Controlled Trial To Compare The Initial Success Rate of Ultrasound Guided Versus Landmark Approach For Placement of Peripheral Intravenous Access Lines in Emergency Department Patients
Brief Summary: The primary objective of this randomized controlled trial (RCT) is to compare the success rate of obtaining peripheral vascular access with ultrasound guidance versus the traditional, landmark approach among patients with varying degrees of intravenous access difficulty. In addition to comparing overall initial success rates of the two methods, we will also compare the success rates by degree of intravenous access difficulty (3 main subject subgroups) and by operator experience (approximately 20 emergency department technicians).

The main hypothesis is that the initial success rate will be significantly higher (5% or greater) for ultrasound guided peripheral intravenous access compared to landmark approach among patients who are judged to have difficult intravenous access but no significant difference (i.e. \< 5%) among patients judged to have easy intravenous access.


Options:
A: Inclusion Criteria:

Age 18 years or older

Self-reported difficult IV Access Patient and any one of the following:

* Greater than 2 sticks in previous admission/hospital encounter
* History of rescue vascular access device (such as US-guided IV, PICC line, midline, or CVC)
* End-stage renal disease on dialysis
* History of IV Drug Use
* History of Sickle Cell Disease

Exclusion Criteria:

Age under 18 years old

* Voluntary withdrawal or refusal to participate
* Previous enrollment into the study
B: Inclusion Criteria:

* 18 years of age or older
* peripheral venous (PIV) access line ordered by a physician during their emergency department visit.

Exclusion Criteria:

* Non-English or non-spanish speaking
* already enrolled in a different study during the ED visit
* too sick, patient requires intravenous access quickly and can not take the time to enroll in study
C: Inclusion Criteria:

* Age over 18 years

Exclusion Criteria:

* Age \<18 years
* Patient disagreement with the insertion of peripheral venous catheter
* Disagreement of the patient with inclusion in a clinical trial
* Contraindication of ultrasound examination of the venous system
* Contraindication of the introduction of peripheral venous cannula on both upper limbs
* Necessity of securing other vein access than peripheral
* Contraindications of cannulation of peripheral vein
D: Inclusion Criteria:

* Admission to the Department of Infectious Disease or Department of Heart Disease.
* ≥18 years of age
* Expected requirement for iv. therapy \>5 days from the day of enrolment as evaluated by a specialist in infectious diseases.
* Mentally competency

Exclusion Criteria:

* Lack of patient consent
* Requirement for a CVC before study eligibility screening or anticipation of an absolute indication for CVC inserted within 24 hours of screening
* Personnel for insertion of midline catheter not available

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Optimizing Kidney Transplant Patients' Informed Consent for Increased Risk Donors
Brief Summary: The objective of this study is to evaluate kidney transplant candidates' comprehension about increased risk donor kidneys necessary for informed consent. We have developed a web-based tool that educates and assesses candidates' comprehension (Inform Me), as a supplement to current informed consent processes. We will then compare the effectiveness of the current informed consent processes supplemented by Inform Me, with the current consent processes alone for kidney transplant.


Options:
A: Inclusion Criteria:

* Diagnosis of end-stage renal disease (ESRD) and on dialysis for \< 1 year
* English-speaking
* Subjects coming in for transplant medical evaluation
* Age \> 18 years

Exclusion Criteria:

* Severe cognitive or visual impairment
B: Inclusion Criteria:

* Adults \>=18 years
* Admitted to the Hospital of the University of Pennsylvania for greater than 24 hours.

Exclusion Criteria:

* Dialysis order within 24 hours of admission
* Dialysis order prior to AKI onset
* Initial creatinine \>=4.0mg/dl
* Prior admission in which patient was randomized.
* Nephrectomy during the admission
* Admission to hospice service
* Admission to observation status
C: Inclusion Criteria:

* Patients with CKD Stage 3B 4 ESRD patients receiving ambulatory dialysis , Patients treated with Renal Transplantation
* In CKD patients stage 3B 4: nephrology care ≤ 3 years, for transplant patients: Renal Transplantation ≥ 3 months but ≤ 12 months
* Patients can use an IT tool or having in their entourage one who knows how to use

Exclusion Criteria:

* Acute Renal Failure at the time of inclusion
* Patient in transplant failure
* Patient with another organ transplant
* Patient whose life is at stake in the short term (Life expectancy \<1 year)
D: Inclusion Criteria:

* English-speaking
* 21 years or older
* Kidney Transplant candidates eligible: 1) completed the first phase of transplant evaluation education, and 2) wait-listed patients expected to receive a transplant within the next 6 months, returning for re-evaluation.

Exclusion Criteria:

* No special classes of study participants, including fetuses, neonates, prisoners, institutionalized individuals, or other vulnerable populations will be included in the proposed study. Although pregnant women will be eligible for participation in the study, they are unlikely to be selected for kidney transplantation.

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: N/A
Brief Summary: The purpose of this study is to determine whether providing increased protein to premature infants in the first week of life allows for better growth during the hospital stay and improved developmental outcomes by age 2.


Options:
A: Inclusion Criteria:

* Infants ≤ 8 months of age
* Infants sensitised to cow's milk and diagnosed with IgE mediated cow's milk allergy confirmed by milk challenge or diagnosis of anaphylaxis to milk within the last 3 months

Exclusion Criteria:

* Infants less than 2500 g at birth
* Infants less than 37 weeks gestation
* Infants with severe concurrent illness
* Use of anti- histamines, systemic corticosteroids, systemic antibiotics or anti-mycotic drugs, and immuno-modulatory drugs
* Infants consuming less than 500ml per day of their usual formula at study entry
* Investigator's uncertainty about the willingness or ability of the subject to comply with the protocol requirements
* Participation in any other studies involving investigational or marketed products concomitantly or within two weeks prior to entry into the study
B: Mothers Inclusion Criteria:

* Healthy, 19-40 years of age
* Plan to exclusively breast-fed or formula-fed

Infants Exclusion Criteria:

* Gestational age \< 37 or \> 42 weeks
* Birth weight \< 2.5kg or \> 4 kg
* Having congenital diseases
* Having birth Asphyxia
* Having birth infections
C: Inclusion Criteria:

* birth weight 400 to 1250 grams
* 24 0/7 to 30 6/7 weeks gestational age

Exclusion Criteria:

* chromosomal, structural, metabolic, endocrine, or renal abnormalities that could affect growth
* infants \>18 hours of age
* infants in extremis who are unlikely to survive past 72 hours
D: Inclusion Criteria:

* mechanically ventilated neonates of all gestational ages and birth weights
* less than 1 month of postnatal age admitted to the NICU
* SNAP (Score of Neonatal Acute Physiology) \> 10
* projected requirement for continued parenteral nutrition of at least 1 week duration

Exclusion Criteria:

* renal or hepatic failure
* requiring insulin administration
* requiring extracorporeal life support
* known inherited metabolic disorders
* known uniformly fatal congenital anomalies

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: An Electronic Alert System for In-Hospital Acute Kidney Injury: A Randomized, Controlled Trial
Brief Summary: This study will randomize hospitalized patients with acute kidney injury (AKI) to usual care, or an electronic alert intervention. The electronic alert will be in the form of a text page that will be sent to the covering clinician and unit pharmacist once per patient with AKI at the time lab results are uploaded. The investigators hypothesize that such an alert will improve outcomes in these patients.


Options:
A: Inclusion Criteria:

* Diagnosis of end-stage renal disease (ESRD) and on dialysis for \< 1 year
* English-speaking
* Subjects coming in for transplant medical evaluation
* Age \> 18 years

Exclusion Criteria:

* Severe cognitive or visual impairment
B: Inclusion Criteria:

* Subjects with a history of kidney transplantation within the last 5 years
* Speaks English
* Can see to read
* Lives in the greater Chicago area and can attend a cognitive interview session
* 18-85 years old

Exclusion Criteria:

* Unable to speak English
* Cognitive impairment or neurologic disease
* Dementia or insufficient cognitive skills to follow instructions provided at a sixth grade language level
* Has had a skin cancer
C: Inclusion Criteria:

* enrolled in Kidney Function Program (KFP)
* previously received KFP-administered dialysis modality education
* personal access to a home computer (ie. either their own or a close friend/family member) with internet access
* most recent eGFR \< or = 20mL/min/1.73m2

Exclusion Criteria:

* inability to provide informed consent
* inability to use a home computer or internet
* inability to understand English (written or spoke)
* severe visual or auditory impairment
D: Inclusion Criteria:

* Adults \>=18 years
* Admitted to the Hospital of the University of Pennsylvania for greater than 24 hours.

Exclusion Criteria:

* Dialysis order within 24 hours of admission
* Dialysis order prior to AKI onset
* Initial creatinine \>=4.0mg/dl
* Prior admission in which patient was randomized.
* Nephrectomy during the admission
* Admission to hospice service
* Admission to observation status

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Effect of Sit-Stand Workstations on Physical Activity in Sedentary Office Workers: A Randomized Crossover Trial
Brief Summary: The purpose of this study was to determine whether the installation of sit-stand work stations could lead to decreased sedentary time and increased physical activity during the workday among sedentary office workers.


Options:
A: Inclusion Criteria:

1. Males or females 50 -70 years of age
2. Able to attend 4 measurement visits with study staff in 3 consecutive weeks
3. Spend at least 8 hours per day sitting
4. Willing and able to wear study device for 21 days
5. Able to read and write in English
6. Able to provide written informed consent

Exclusion Criteria:

1. Do not sit for at least 8 hours per day
2. Unable to attend 4 visits
3. Diagnosis of serious chronic condition that would limit the ability to stand
B: Inclusion Criteria:

* Employee of Janssen Pharmaceutics Belgium
* Physically inactive lifestyle (not reaching 150 minutes of moderate-to-vigorous physical activity a week)
* PAR-Q questionnaire all answers negative, if one or more answers are positive a permission of a physician is necessary

Exclusion Criteria:

* none
C: Inclusion Criteria:

Worksite-level inclusion criteria:

* Size: Small to moderate size worksite (20-60 employees)
* Schedule: \>80% of employees full time
* Occupation: Seated office work, primarily computer- and- telephone-based work, little movement or walking
* Wellness environment: Not currently undergoing a wellness program aimed at increasing activity at work
* Workstations: Willing to have sit-stand workstations installed at a worksite
* Willing to be randomized: Willing to be randomized to either intervention conditions

Member-level inclusion criteria:

* Age: 18 years and older
* Health status: Generally good health and able to safely increase LPA and reduce sitting time
* Employment status: Any sedentary job, sitting most of the say, little standing or walking
* Occupation: Traditional sitting desk, willing to have a sit-stand workstation installed at desk
* Workstation: traditional sitting desk;willing to have a sit-stand workstation installed at desk

Exclusion Criteria:

* contraindication to prolonged standing at work
D: Inclusion Criteria:

* Mostly sedentary (sitting ≥ 4 hour) during the workday.
* Age ≥ 18
* Anticipated using a single computer workstation for 20 hours or more per week

Exclusion Criteria:

* Unable to stand for at least two hours per workday (two hours over the whole workday, not consecutively)
* Reported severe musculoskeletal symptoms, specifically lower extremity or lower back pain.
* Diagnosed with or under treatment for diabetes, heart disease, cancer, orthostatic hypertension, varicose vein, autoimmune disease, or other chronic diseases.
* Pregnant women

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Effect of Sit-Stand Workstations on Physical Activity in Sedentary Office Workers: A Randomized Crossover Trial
Brief Summary: The purpose of this study was to determine whether the installation of sit-stand work stations could lead to decreased sedentary time and increased physical activity during the workday among sedentary office workers.


Options:
A: Inclusion Criteria:

* Mostly sedentary (sitting ≥ 4 hour) during the workday.
* Age ≥ 18
* Anticipated using a single computer workstation for 20 hours or more per week

Exclusion Criteria:

* Unable to stand for at least two hours per workday (two hours over the whole workday, not consecutively)
* Reported severe musculoskeletal symptoms, specifically lower extremity or lower back pain.
* Diagnosed with or under treatment for diabetes, heart disease, cancer, orthostatic hypertension, varicose vein, autoimmune disease, or other chronic diseases.
* Pregnant women
B: Inclusion Criteria:

* Participants were required to be sedentary, between 18-65 years old, have a BMI above 25.0 kg/m2 and physical inactive (not meeting the MVPA recommendations and not exceed 6000 steps/day). In addition subjects had to be free of any major disease with a general healthy status warranted.

Exclusion Criteria:

* Taking any medication or dietary supplements that may interfere with body composition or energy expenditure regulation, performing more than 5000 steps/day and meeting actual MVPA recommendations
C: Inclusion Criteria:

* Office workers with mainly sedentary tasks
* BMI 25-40

Exclusion Criteria:

* Severe depression and/or anxiety
* Exhaustion disorder
* Diabetes Mellitus
* Severe cardiovascular disease
* Severe kidney disease
* Musculoskeletal disorders that prohibit walking on a treadmill
* Contraindications for physical activity
* Thyroidea illness
* Pregnancy

For fMRI-study, additional exclusion criteria are:

* Implanted metal- or electrical devices
* Pregnancy
* Extraneous metal pieces in the body
D: Inclusion Criteria:

* We will recruit overweight/obese (body mass index 25.0-40.0 kg/m2) adults (18-65 years) working in full-time (minimum 35 hours/week), sedentary (self-report sitting \>75% work time) occupations at an independent work site.

Exclusion Criteria:

* Working in an office that will not meet the space or electrical requirements of the active workstation, acute or chronic illness not under treatment of a provider, orthopedic limitations that prohibit physical activity, current or planned pregnancy, hospitalization from a physical or mental disorder in the past six months and/or taking medication that may impair physical activity

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Effect of Sit-Stand Workstations on Physical Activity in Sedentary Office Workers: A Randomized Crossover Trial
Brief Summary: The purpose of this study was to determine whether the installation of sit-stand work stations could lead to decreased sedentary time and increased physical activity during the workday among sedentary office workers.


Options:
A: Inclusion Criteria:

* full-time member of staff
* access to a work telephone and desktop computer with internet

Exclusion Criteria:

* have a cardiovascular or metabolic disease
* taking any medication
* pregnant
* planned absence \> 1 week during the trial
B: Inclusion Criteria:

* regional Northern California KP employees

Exclusion Criteria:

* none
C: Inclusion Criteria:

* Mostly sedentary (sitting ≥ 4 hour) during the workday.
* Age ≥ 18
* Anticipated using a single computer workstation for 20 hours or more per week

Exclusion Criteria:

* Unable to stand for at least two hours per workday (two hours over the whole workday, not consecutively)
* Reported severe musculoskeletal symptoms, specifically lower extremity or lower back pain.
* Diagnosed with or under treatment for diabetes, heart disease, cancer, orthostatic hypertension, varicose vein, autoimmune disease, or other chronic diseases.
* Pregnant women
D: Inclusion Criteria:

* Office employees (university administrative and academic staff) with low and moderate physical activity levels (0 to 3,000 MET·min·wk-1 according to the International Physical Activity Questionnaire)

Exclusion Criteria:

* Highly active office employees (\>3,000 MET·min·wk-1 according to the International Physical Activity Questionnaire)

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Evaluation of Two Community Based Screening Strategies for Severe Acute Malnutrition in Children Aged 6-59 Months in the Mirria District, Niger
Brief Summary: The objective of this study is to determine the efficacity of a community strategy for screening children 06-59 months old for Severe Acute Malnutrition (SAM) conducted by their mothers' compared with a community screening strategy conducted by Community Health Workers.


Options:
A: Inclusion Criteria:

* Age 6-36 months at the time of enrollment
* Live within the study area for the duration of the intervention and follow-up period

Exclusion Criteria:

* Unavailable for enrollment on 3 separate household visits
* Parental refusal to give informed consent
B: Inclusion Criteria:

* Resident of one of the 11 catchment areas
* Seeks routine health care from a health facility in Neno District

Exclusion Criteria:

* Not a resident and/or does not reside predominantly in Neno District
C: Inclusion Criteria:

* living in one of the study cluster (villages)
* no story of allergy to any of the study drugs
* history of fever or body temperature \>= 38.5°C

Exclusion Criteria:

* signs of severity/complications like impaired consciousness, convulsions, fast breathing etc
D: Inclusion Criteria:

* children aged 06-59 months at the time of the study
* children who live in a village in the health district participating in the study

Exclusion Criteria:

* children whose legal guardian refuses to participate in the study

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Safety and Efficacy of Misoprostol Versus Oxytocin for Prevention of Post Partum Hemorrhage
Brief Summary: Post partum Hemorrhage (PPH) is one of three main causes of death in pregnant women. Oxytocin is widely used for prevention of PPH. Some studies suggested misoprostol as an alternative treatment when Oxytocin isn't available. The aim of this study is to compare the safety and efficacy of Oxytocin and misoprostol for prevention of PPH.


Options:
A: Inclusion Criteria:

* were women with singleton pregnancy
* with cephalic presentation
* who had NVD spontaneously or by induction

Exclusion Criteria:

* placenta previa
* placental detachment
* coagulation problems
* previous CS
* macrosomia
* Polyhydramnios
* and uncontrolled asthma
B: Inclusion Criteria:

* Women\>18 years,
* during first stage of normal labor,
* at 36 to 42 weeks,
* with epidural analgesia and informed signed consent

Exclusion Criteria:

* Cesarean section delivery,
* clotting disorders,
* prostaglandin allergy,
* absent consent.
C: Inclusion Criteria:

* having a singleton pregnancy above 37th gestational week
* normal live vaginal delivery with cephalic presentation
* being in active labor

Exclusion Criteria:

* Fetal demise
* multiple pregnancy
* known coagulation disorder
* presentation anomalies
* placental pathology
* liver disease
* thrombocytopenia
* hypertension or being currently on anticoagulants
* having a cesarean section, operative delivery or deep vaginal tear
* chorioamnionitis
* developing HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count) or DIC (disseminated intravascular coagulation) before delivery
D: Inclusion Criteria:

* Women who have given birth to 1 or more live-born infants (para 1 or more)
* Vaginal delivery

Exclusion Criteria:

* Refusal or inability to give informed consent
* Delivery regarded as abortion according to local gestational age limits
* Inability to take misoprostol sublingually
* Cesarean section
* Assisted vaginal delivery

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Medicines Advice Service: A Randomised Controlled Trial of a Pharmacy-based Telephone Intervention to Support Patients Taking Medication for a Long-term Condition
Brief Summary: The purpose of this study is to find out whether talking to a pharmacist on the telephone can help to support people taking medicine for a long-term condition.


Options:
A: Inclusion Criteria:

* Blood pressure inadequate control (systolic blood pressure ≥ 160 or diastolic blood pressure ≥ 100 mmHg) or
* Diabetes mellitus inadequate Control( ≥ 200 mg/dL) or hypoglycemia moderate or severe
* Be referred to clinical care.

Exclusion Criteria:

* \< 18 years
* Not resident of Porto Alegre
* Diabetes mellitus type I
* Unable to answer the questionnaire or to sign the informed consent form
* Hospital admission
* Death
B: Inclusion criteria:

* Accessed via EHR, were: \>=10 chronic prescription medications
* History of acute myocardial infarction or congestive heart failure
* Admission from skilled nursing facility
* History of transplant, or active anticoagulant, insulin, or narrow therapeutic index medications.

Exclusion criteria:(supersedes inclusion criteria)

* Admitted to pediatric, trauma or transplant services with pharmacists
C: Inclusion Criteria:

Age: 18 years or older

* Patients receiving ambulatory treatment for hypertension in a hospital setting
* The patient or a carer usually dispenses the patient's medications
* Patient lives in the Southern Region of Denmark
* Written consent

Exclusion Criteria:

* Lives in a care home or institution
* Receive dose dispensed medicine from a pharmacy
* Medicine is dispensed by a nurse in the patient's home
* Correctional mental health patients
D: Inclusion Criteria:

* Patients prescribed medication(s) for at least one of the following conditions: type 2 diabetes, hyperlipidemia

Exclusion Criteria:

* Patients living outside of England
* Patients with no access to a telephone
* Patients under the age of 18
* Patients unable to give written informed consent
* Patients on drugs for dementia
* Patients showing signs of dementia or cognitive impairment in conversation
* Patients with substantial hearing or sight impairment
* Patients whose medications are ordered by a caregiver/family member
* Patients with insufficient English to take part in the telephone intervention
* Patients living with someone already taking part in the study
* Patients newly prescribed a medication for the conditions listed in the inclusion criteria

Answer: D