TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase II/III, Multicenter, Randomized, Double-Blind, Double-Dummy Study to Assess Similarity of the Efficacy, Pharmacokinetics, Safety and Immunogenicity of Abatacept Administered Subcutaneously or Intravenously in Japanese Subjects With Rheumatoid Arthritis, Receiving Background Methotrexate, and Experiencing an Inadequate Response to Methotrexate
Brief Summary: The purpose of this study is to assess the efficacy, pharmacokinetics, safety, and immunogenicity of abatacept after subcutaneous and intravenous administration in Japanese participants with active rheumatoid arthritis and inadequate response to methotrexate.


Options:
A: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: tocilizumab [RoActemra/Actemra] | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Drug: Methotrexate | Intervention Type: DRUG; Name: Methotrexate; Assigned to Arm(s): 2 | Intervention Type: DRUG; Name: tocilizumab [RoActemra/Actemra]; Assigned to Arm(s): 1
B: Intervention Type: DRUG; Name: Certolizumab Pegol; Assigned to Arm(s): N/A
C: Arm Label: Subcutaneous (SC) abatacept, 125 mg; Type: ACTIVE_COMPARATOR; Interventions: Drug: Subcutaneous (SC) abatacept | Arm Label: Intravenous (IV) abatacept, 125 mg; Type: ACTIVE_COMPARATOR; Interventions: Drug: Intravenous (IV) abatacept | Intervention Type: DRUG; Name: Intravenous (IV) abatacept; Assigned to Arm(s): Intravenous (IV) abatacept, 125 mg | Intervention Type: DRUG; Name: Subcutaneous (SC) abatacept; Assigned to Arm(s): Subcutaneous (SC) abatacept, 125 mg
D: Arm Label: Tocilizumab 4 mg/kg + Methotrexate; Type: EXPERIMENTAL; Interventions: Drug: tocilizumab [RoActemra/Actemra], Drug: Methotrexate | Arm Label: Tocilizumab 8 mg/kg + Methotrexate; Type: EXPERIMENTAL; Interventions: Drug: tocilizumab [RoActemra/Actemra], Drug: Methotrexate | Arm Label: Placebo + Methotrexate; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo, Drug: Methotrexate | Intervention Type: DRUG; Name: tocilizumab [RoActemra/Actemra]; Assigned to Arm(s): Tocilizumab 4 mg/kg + Methotrexate, Tocilizumab 8 mg/kg + Methotrexate | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo + Methotrexate | Intervention Type: DRUG; Name: Methotrexate; Assigned to Arm(s): Placebo + Methotrexate, Tocilizumab 4 mg/kg + Methotrexate, Tocilizumab 8 mg/kg + Methotrexate

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Domiciliary Diagnosis and Follow up in Obstructive Apnoea Syndrome
Brief Summary: The aim of the investigators study was to evaluate the effectiveness of a home programme (diagnosis and follow-up) in patients with Obstructive Sleep Apnea (OSA) syndrome treated with CPAP and to analyze the cost of this approach.


Options:
A: Arm Label: OSA Health Education & Support Group; Type: EXPERIMENTAL; Interventions: Behavioral: Peer Based Sleep Health Education and Social Support | Arm Label: Attention Control Group; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Attention Control Group | Intervention Type: BEHAVIORAL; Name: Peer Based Sleep Health Education and Social Support; Assigned to Arm(s): OSA Health Education & Support Group | Intervention Type: BEHAVIORAL; Name: Attention Control Group; Assigned to Arm(s): Attention Control Group
B: Arm Label: Enhanced education and Enhanced follow up; Type: EXPERIMENTAL; Interventions: Other: Enhanced education, Other: Usual follow up | Arm Label: Usual education and Usual follow up; Type: ACTIVE_COMPARATOR; Interventions: Other: Usual education, Other: Enhanced follow up | Arm Label: Enhanced education and Usual follow up; Type: EXPERIMENTAL; Interventions: Other: Enhanced education, Other: Enhanced follow up | Arm Label: Usual education with Enhanced follow up; Type: EXPERIMENTAL; Interventions: Other: Usual education, Other: Usual follow up | Intervention Type: OTHER; Name: Enhanced education; Assigned to Arm(s): Enhanced education and Enhanced follow up, Enhanced education and Usual follow up | Intervention Type: OTHER; Name: Usual education; Assigned to Arm(s): Usual education and Usual follow up, Usual education with Enhanced follow up | Intervention Type: OTHER; Name: Usual follow up; Assigned to Arm(s): Enhanced education and Enhanced follow up, Usual education with Enhanced follow up | Intervention Type: OTHER; Name: Enhanced follow up; Assigned to Arm(s): Enhanced education and Usual follow up, Usual education and Usual follow up
C: Arm Label: Primary.; Type: EXPERIMENTAL; Interventions: Device: Diagnosis, autoCPAP, follow up. | Arm Label: Hospital; Type: ACTIVE_COMPARATOR; Interventions: Device: Diagnosis, autoCPAP, follow up. | Intervention Type: DEVICE; Name: Diagnosis, autoCPAP, follow up.; Assigned to Arm(s): Hospital, Primary.
D: Arm Label: Domiciliary group; Type: ACTIVE_COMPARATOR; Interventions: Other: Diagnosis and monitoring of OSA patients | Arm Label: Hospital Group; Type: ACTIVE_COMPARATOR; Interventions: Other: Diagnosis and monitoring of OSA patients | Arm Label: Mixed Group; Type: ACTIVE_COMPARATOR; Interventions: Other: Diagnosis and monitoring of OSA patients | Intervention Type: OTHER; Name: Diagnosis and monitoring of OSA patients; Assigned to Arm(s): Domiciliary group, Hospital Group, Mixed Group

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Seasonal Impact of Iron Fortification on Malaria Incidence in Ghanaian Children
Brief Summary: Iron deficiency and iron deficiency anemia (IDA) are the most prevalent micronutrient deficiencies on a worldwide basis, especially in developing countries. The impact of severe IDA can have mortal consequences, since without adequate hemoglobin, the brain and body become deprived of oxygen and, if allowed to continue, death may ensue. It has been shown that iron supplementation in infants and young children can enhance child development, however, it may also result in increased rates of malaria in high burden areas.

The primary objective of this study is to determine the impact of providing encapsulated iron (as a powder added to complementary foods) on the susceptibility to clinical malaria among anemic and non-anemic infants and young children (6-24 months of age) living in a high malaria burden area.

The value of performing this research in Ghana is primarily that malaria and anemia remain the most important causes of death and morbidity.


Options:
A: Intervention Type: DRUG; Name: ferrous sulphate (drug); Assigned to Arm(s): N/A
B: Intervention Type: DRUG; Name: zinc sulphate dietary supplement; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: iron sulphate-folic acid dietary supplement; Assigned to Arm(s): N/A
C: Arm Label: Vitamin/mineral fortificant with iron; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Sprinkles® | Arm Label: Vitamin/mineral fortificant without iron; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: vitamin/mineral fortificant without iron | Intervention Type: DIETARY_SUPPLEMENT; Name: Sprinkles®; Assigned to Arm(s): Vitamin/mineral fortificant with iron | Intervention Type: DIETARY_SUPPLEMENT; Name: vitamin/mineral fortificant without iron; Assigned to Arm(s): Vitamin/mineral fortificant without iron
D: Arm Label: Symptomatic malaria infection; Type: OTHER; Interventions: Dietary Supplement: Fe-57 orally, Fe-58 intravenously | Arm Label: Asymptomatic malaria infection; Type: OTHER; Interventions: Dietary Supplement: Fe-57 orally, Fe-58 intravenously | Arm Label: Hookworm infection; Type: OTHER; Interventions: Dietary Supplement: Fe-57 orally, Fe-58 intravenously | Arm Label: Schistosoma haematobium infection; Type: OTHER; Interventions: Dietary Supplement: Fe-57 orally, Fe-58 intravenously | Intervention Type: DIETARY_SUPPLEMENT; Name: Fe-57 orally, Fe-58 intravenously; Assigned to Arm(s): Asymptomatic malaria infection, Hookworm infection, Schistosoma haematobium infection, Symptomatic malaria infection

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized Control Trial of Misoprostol vs. Placebo for Cervical Preparation in IUD Insertion for Nulliparous Women
Brief Summary: The purpose of this study is to evaluate if the use of misoprostol can make it easier for a provider, and less painful for a woman, to place an IUD if she has never had a child before.


Options:
A: Arm Label: LNG-IUS; Type: N/A; Interventions: Other: Evaluation of uterine size and posture with ultrasound, IUD insertion, one year follow-up. | Arm Label: Cu-IUD; Type: N/A; Interventions: Other: Evaluation of uterine size and posture with ultrasound, IUD insertion, one year follow-up. | Intervention Type: OTHER; Name: Evaluation of uterine size and posture with ultrasound, IUD insertion, one year follow-up.; Assigned to Arm(s): Cu-IUD, LNG-IUS
B: Arm Label: misoprostol; Type: EXPERIMENTAL; Interventions: Drug: Misoprostol | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Misoprostol; Assigned to Arm(s): misoprostol | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
C: Arm Label: misoprostol; Type: EXPERIMENTAL; Interventions: Drug: Misoprostol | Arm Label: placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Misoprostol; Assigned to Arm(s): misoprostol | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): placebo
D: Arm Label: Placebo gel; Type: PLACEBO_COMPARATOR; Interventions: Procedure: Placebo Gel | Arm Label: Nitroprusside Gel; Type: EXPERIMENTAL; Interventions: Procedure: Nitroprusside Gel | Intervention Type: PROCEDURE; Name: Nitroprusside Gel; Assigned to Arm(s): Nitroprusside Gel | Intervention Type: PROCEDURE; Name: Placebo Gel; Assigned to Arm(s): Placebo gel

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: Patients undergoing open appendectomy for acute appendicitis were enrolled in a randomized prospective study.


Options:
A: Arm Label: Post op care; Type: ACTIVE_COMPARATOR; Interventions: Other: Oxygen delivery, Other: Oxygen administration | Arm Label: Oxygen administration- different %; Type: ACTIVE_COMPARATOR; Interventions: Other: Oxygen administration | Intervention Type: OTHER; Name: Oxygen delivery; Assigned to Arm(s): Post op care | Intervention Type: OTHER; Name: Oxygen administration; Assigned to Arm(s): Oxygen administration- different %, Post op care
B: Arm Label: Liberal Oxygenation (LO) group; Type: ACTIVE_COMPARATOR; Interventions: Drug: Modulation of Inspired Fraction of Oxygen (FiO2) | Arm Label: Conservative Oxygenation (CO) group; Type: EXPERIMENTAL; Interventions: Drug: Modulation of Inspired Fraction of Oxygen (FiO2) | Intervention Type: DRUG; Name: Modulation of Inspired Fraction of Oxygen (FiO2); Assigned to Arm(s): Conservative Oxygenation (CO) group, Liberal Oxygenation (LO) group
C: Arm Label: Low oxygenation target; Type: EXPERIMENTAL; Interventions: Drug: Oxygen | Arm Label: High oxygenation target; Type: ACTIVE_COMPARATOR; Interventions: Drug: Oxygen | Intervention Type: DRUG; Name: Oxygen; Assigned to Arm(s): Low oxygenation target | Intervention Type: DRUG; Name: Oxygen; Assigned to Arm(s): High oxygenation target
D: Arm Label: Lower SpO2 Target; Type: ACTIVE_COMPARATOR; Interventions: Other: Lower SpO2 Target | Arm Label: Intermediate SpO2 Target; Type: ACTIVE_COMPARATOR; Interventions: Other: Intermediate SpO2 Target | Arm Label: Higher SpO2 Target; Type: ACTIVE_COMPARATOR; Interventions: Other: Higher SpO2 Target | Intervention Type: OTHER; Name: Lower SpO2 Target; Assigned to Arm(s): Lower SpO2 Target | Intervention Type: OTHER; Name: Intermediate SpO2 Target; Assigned to Arm(s): Intermediate SpO2 Target | Intervention Type: OTHER; Name: Higher SpO2 Target; Assigned to Arm(s): Higher SpO2 Target

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: Patients undergoing open appendectomy for acute appendicitis were enrolled in a randomized prospective study.


Options:
A: Arm Label: Post op care; Type: ACTIVE_COMPARATOR; Interventions: Other: Oxygen delivery, Other: Oxygen administration | Arm Label: Oxygen administration- different %; Type: ACTIVE_COMPARATOR; Interventions: Other: Oxygen administration | Intervention Type: OTHER; Name: Oxygen delivery; Assigned to Arm(s): Post op care | Intervention Type: OTHER; Name: Oxygen administration; Assigned to Arm(s): Oxygen administration- different %, Post op care
B: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Other: Oxygen by mask | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Other: Oxygen by mask | Intervention Type: OTHER; Name: Oxygen by mask; Assigned to Arm(s): 1 | Intervention Type: OTHER; Name: Oxygen by mask; Assigned to Arm(s): 2
C: Intervention Type: OTHER; Name: Mild intraoperative hypercapnia (50 mmHg vs. 30 mmHg); Assigned to Arm(s): N/A | Intervention Type: OTHER; Name: Supplemental oxygen (80% vs. 30%); Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Dexamethasone; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): N/A
D: Arm Label: 80% oxygen group; Type: N/A; Interventions: Drug: Oxygen | Arm Label: 30% oxygen group; Type: N/A; Interventions: Drug: Oxygen | Intervention Type: DRUG; Name: Oxygen; Assigned to Arm(s): 30% oxygen group, 80% oxygen group

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Effect of Arthroscopic Partial Meniscectomy or Exercise Therapy as Treatment of Degenerative Meniscus Tears in Middle-aged Patients. A Randomized, Controlled Trial
Brief Summary: This study is conducted as a collaboration between NAR, Orthopedic Department, Oslo University Hospital,Ullevaal, Hjelp24Nimi Oslo, Martina Hansens Hospital Norway, and University of Southern Denmark, Odense, Denmark.

The investigators hypothesize that exercise is more effective than arthroscopic partial meniscectomy: a) on self-reported outcomes, functional performance and muscle strength in middle-aged patients subsequent to arthroscopic partial meniscectomy for a degenerative meniscus tear, and b) in preventing further development of knee osteoarthritis (OA).


Options:
A: Arm Label: Arthroscopy; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Knee arthroscopy | Arm Label: Exercise therapy; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: PROCEDURE; Name: Knee arthroscopy; Assigned to Arm(s): Arthroscopy
B: Arm Label: Operative (O); Type: ACTIVE_COMPARATOR; Interventions: Procedure: Operative (partial arthroscopy) | Arm Label: Conservative (K); Type: SHAM_COMPARATOR; Interventions: Procedure: Conservative (diagnostic arthroscopy) | Intervention Type: PROCEDURE; Name: Operative (partial arthroscopy); Assigned to Arm(s): Operative (O) | Intervention Type: PROCEDURE; Name: Conservative (diagnostic arthroscopy); Assigned to Arm(s): Conservative (K)
C: Arm Label: Arthroscopic partial meniscectomy; Type: EXPERIMENTAL; Interventions: Procedure: Arthroscopic partial menisectomy | Arm Label: Exercise Therapy; Type: EXPERIMENTAL; Interventions: Other: Supervised neuromuscular and strength training | Intervention Type: PROCEDURE; Name: Arthroscopic partial menisectomy; Assigned to Arm(s): Arthroscopic partial meniscectomy | Intervention Type: OTHER; Name: Supervised neuromuscular and strength training; Assigned to Arm(s): Exercise Therapy
D: Arm Label: Arthroscopy; Type: EXPERIMENTAL; Interventions: Procedure: Arthroscopic meniscal repair or resection | Arm Label: Exercise and Education; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Exercise and education | Intervention Type: PROCEDURE; Name: Arthroscopic meniscal repair or resection; Assigned to Arm(s): Arthroscopy | Intervention Type: BEHAVIORAL; Name: Exercise and education; Assigned to Arm(s): Exercise and Education

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: ACTIVITAL: Health Promotion Intervention in Ecuadorian Adolescents to Promote Healthy Dietary and Physical Activity Patterns.
Brief Summary: Worldwide, low-income and middle-income countries are undergoing rapid demographic and nutritional changes. Populations tend to move from their traditional food habits towards dietary patterns characterized by a more energy-dense diet, while urbanization and technology (work, transport) play a role in the reduction of their physical activity. This shift towards energy-dense diets and lower levels of physical activity are key determinants of chronic diseases. Nowadays, childhood overweight and obesity are becoming a major threat to public health all in low-income and middle-income countries. Clearly, not properly addressing this health problem will only aggravate the already enormous impact of chronic diseases on the social and economic development of these countries. This study aims to develop a culturally relevant school-based prevention intervention among Ecuadorian adolescents (11-13 years old) in Cuenca. The intervention will target behavioural nutrition and physical activity. Intervention strategies will be developed based on theoretical behavioural change models integrated in two complementary frameworks, i.e. (i) the Intervention Mapping protocol, and (ii) the Comprehensive Participatory Planning and Evaluation protocol.

The study includes two phases:

1. A formative research, which will be conducted in order to understand the causality of the school environment and unhealthy eating and low physical activity levels in school-going adolescents, aged 12-13 years old.
2. A paired, cluster-randomized controlled trial including 1400 adolescents (12-13 years old) from 10 pairs of schools (i.e. clusters). Within each pair of clusters, one cluster will be randomly assigned to the intervention and the other to the control group.


Options:
A: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Other: Experimental | Arm Label: 2; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Experimental; Assigned to Arm(s): 1
B: Arm Label: "Fortaleça sua Saúde" program; Type: EXPERIMENTAL; Interventions: Behavioral: "Fortaleça sua Saúde" program | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: "Fortaleça sua Saúde" program; Assigned to Arm(s): "Fortaleça sua Saúde" program
C: Arm Label: HEALTH[e]TEEN; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: HEALTH[e]TEEN | Arm Label: HEALTH[e]TEEN + CST; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: HEALTH[e]TEEN + CST | Intervention Type: BEHAVIORAL; Name: HEALTH[e]TEEN; Assigned to Arm(s): HEALTH[e]TEEN | Intervention Type: BEHAVIORAL; Name: HEALTH[e]TEEN + CST; Assigned to Arm(s): HEALTH[e]TEEN + CST
D: Arm Label: New Moves Intervention Group; Type: EXPERIMENTAL; Interventions: Behavioral: New Moves | Arm Label: control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: New Moves; Assigned to Arm(s): New Moves Intervention Group

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Phase II Trial of Subcutaneous Methylnaltrexone in the Treatment of Severe Opioid-induced Constipation in Cancer Patients
Brief Summary: The purpose of this study is to evaluate the efficacy of methylnaltrexone in relieving opioid-induced constipation in cancer patients at various stages of disease.


Options:
A: Arm Label: Oxycodone Hydrochloride Tablets; Type: ACTIVE_COMPARATOR; Interventions: Drug: Oxycodone | Arm Label: Oxycodone Naloxone Tablets; Type: EXPERIMENTAL; Interventions: Drug: Oxycodone/Naloxone | Intervention Type: DRUG; Name: Oxycodone; Assigned to Arm(s): Oxycodone Hydrochloride Tablets | Intervention Type: DRUG; Name: Oxycodone/Naloxone; Assigned to Arm(s): Oxycodone Naloxone Tablets
B: Arm Label: Targinact® (oxycodon/naloxon); Type: N/A; Interventions: Drug: Targinact® (oxycodon/naloxon) | Intervention Type: DRUG; Name: Targinact® (oxycodon/naloxon); Assigned to Arm(s): Targinact® (oxycodon/naloxon)
C: Arm Label: Arm 1; Type: EXPERIMENTAL; Interventions: Drug: SC Methylnaltrexone | Arm Label: Arm 3; Type: PLACEBO_COMPARATOR; Interventions: Drug: SC Placebo | Arm Label: Arm 2; Type: EXPERIMENTAL; Interventions: Drug: SC Methylnaltrexone | Intervention Type: DRUG; Name: SC Methylnaltrexone; Assigned to Arm(s): Arm 1 | Intervention Type: DRUG; Name: SC Placebo; Assigned to Arm(s): Arm 3 | Intervention Type: DRUG; Name: SC Methylnaltrexone; Assigned to Arm(s): Arm 2
D: Arm Label: Methylnaltrexone bromide; Type: EXPERIMENTAL; Interventions: Drug: Methylnaltrexone bromide | Intervention Type: DRUG; Name: Methylnaltrexone bromide; Assigned to Arm(s): Methylnaltrexone bromide

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Phase II Trial of Subcutaneous Methylnaltrexone in the Treatment of Severe Opioid-induced Constipation in Cancer Patients
Brief Summary: The purpose of this study is to evaluate the efficacy of methylnaltrexone in relieving opioid-induced constipation in cancer patients at various stages of disease.


Options:
A: Arm Label: Oxycodone Hydrochloride Tablets; Type: ACTIVE_COMPARATOR; Interventions: Drug: Oxycodone | Arm Label: Oxycodone Naloxone Tablets; Type: EXPERIMENTAL; Interventions: Drug: Oxycodone/Naloxone | Intervention Type: DRUG; Name: Oxycodone; Assigned to Arm(s): Oxycodone Hydrochloride Tablets | Intervention Type: DRUG; Name: Oxycodone/Naloxone; Assigned to Arm(s): Oxycodone Naloxone Tablets
B: Arm Label: Arm 1; Type: EXPERIMENTAL; Interventions: Drug: SC Methylnaltrexone | Arm Label: Arm 3; Type: PLACEBO_COMPARATOR; Interventions: Drug: SC Placebo | Arm Label: Arm 2; Type: EXPERIMENTAL; Interventions: Drug: SC Methylnaltrexone | Intervention Type: DRUG; Name: SC Methylnaltrexone; Assigned to Arm(s): Arm 1 | Intervention Type: DRUG; Name: SC Placebo; Assigned to Arm(s): Arm 3 | Intervention Type: DRUG; Name: SC Methylnaltrexone; Assigned to Arm(s): Arm 2
C: Arm Label: 'Oxycodone/Naloxone'; Type: EXPERIMENTAL; Interventions: Drug: Oxycodone/Naloxone | Arm Label: Oxycodone; Type: ACTIVE_COMPARATOR; Interventions: Drug: Oxycodone(single compound) | Intervention Type: DRUG; Name: Oxycodone/Naloxone; Assigned to Arm(s): 'Oxycodone/Naloxone' | Intervention Type: DRUG; Name: Oxycodone(single compound); Assigned to Arm(s): Oxycodone
D: Arm Label: Methylnaltrexone bromide; Type: EXPERIMENTAL; Interventions: Drug: Methylnaltrexone bromide | Intervention Type: DRUG; Name: Methylnaltrexone bromide; Assigned to Arm(s): Methylnaltrexone bromide

Answer: D