TrialPanorama/Dataset huggingface dataset:
Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Effect of Music Therapy on Newborns
Brief Summary: The clinical study is evaluating the impact of music therapy on neonates, specifically infants with neonatal opioid withdrawal syndrome (NOWS). The goal is to study the effect of music therapy on an infant's behavioral (i.e feeding patterns, sleep patterns, severity of withdrawal) and physiological systems (i.e. heart rate, respiratory rate). The investigators are also studying the impact of music therapy on the infant's utilization of resources (i.e. total opioid usage and total length of stay).


Options:
A: Inclusion Criteria:

* Infants greater than or equal to 36 weeks EGA
* Intrauterine opioid exposure
* Primary diagnosis of NAS
* Parental permission to participate

Exclusion Criteria:

* Infants less than 36 weeks EGA
* Major congenital anomalies
* Latrogenic drug withdrawal
* Diagnosis of infection or respiratory distress
* Prior initiation of opioid replacement therapy
* Non-English speaking
* Infants with respiratory conditions
B: Inclusion Criteria:

* Full term healthy infants, needing a heel-prick for metabolic screening;
* Informed consent obtained from parents.

Exclusion Criteria:

- Presence of sedation or analgesia (other than non pharmacological analgesia given during the experimental procedure)
C: Inclusion Criteria:

1. Admitted to the NICU or newborn nursery
2. Corrected gestational age 34 weeks or older
3. No identified hearing disorder
4. Do not have a diagnosed developmental disability (i.e. Down Syndrome)
5. Do not have Fetal Alcohol Syndrome
6. Medically cleared to participate in the study
7. Parent or legal guardian able/willing to give consent \& complete surveys.

Exclusion Criteria:

1. Corrected gestational age \< 34 weeks old
2. Has an identified hearing disorder
3. Has diagnosed developmental disability (i.e. Down syndrome)
4. Has Fetal Alcohol Syndrome
5. Is not medically cleared to participate in the study
6. Parent or legal guardian unable/unwilling to give consent
D: Inclusion Criteria:

Infants who meet the following inclusion criteria will be eligible to participate in the study irrespective of race, religion, ethnicity, or gender:

* Admitted to the NICU immediately postpartum
* Gestational age 28 weeks or older
* No identified hearing disorder
* Do not have a diagnosed developmental disability (i.e. Down Syndrome)
* Do not have Fetal Alcohol Syndrome
* Medically cleared to participate in the study by nurse or neonatologist
* Parent or legal guardian able/willing to give consent \& complete the PBQ (Postpartum Bonding Questionnaire)

Exclusion Criteria:

* Admitted to the NICU at any time other than immediately postpartum
* Gestational age \<28 weeks old
* Has an identified hearing disorder
* Has diagnosed developmental disability (i.e. Down syndrome)
* Has Fetal Alcohol Syndrome
* Is not medically cleared to participate in the study by the nurse or neonatologist
* Parent or legal guardian unable/unwilling to give consent

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Outcome Following Truncation of Asparaginase in the NOPHO ALL2008 Protocol
Brief Summary: This study aimed to investigate the outcome of patients who had their asparaginase treatment truncated in the NOPHO ALL2008 protocol.


Options:
A: Inclusion Criteria:

* Histologically confirmed acute lymphoblastic leukemia (ALL)
* No secondary ALL
* More than 4 weeks since prior chemotherapy
* More than 4 weeks since prior steroids

Exclusion Criteria:

* Prior disease that would preclude treatment with chemotherapy
B: Inclusion Criteria:

* Confirmed diagnosis of ALL or lymphoblastic leukemia
* No prior therapy except short courses of corticosteroids, a single dose of IT cytarabine or emergent radiation to the mediastinum or other life-threatening masses

Exclusion Criteria:

* Have received more than 7 days of corticosteroids in the preceding 4 weeks or more than 28 days of corticosteroids in the preceding 6 months
* Have received any chemotherapy or radiotherapy for previous malignancy
* Receiving any other investigational agent
* Known to be HIV positive
* Uncontrolled intercurrent illness
* Pregnant or breastfeeding
* History of previous malignancy
C: Inclusion Criteria:

- Children treated according to the NOPHO ALL2008 protocol from the 1st of July 2008 - 28th of February 2016.

Exclusion Criteria:

* Bilineage ALL
* Pre-treatment with glucocorticosteroids or other antileukemic agents for more than 1 week
* ALL predisposition syndromes
* Previous cancer
* Off protocol administration of additional chemotherapy during induction therapy
* Sexually active females not using contraception
D: DISEASE CHARACTERISTICS:

* Diagnosis of acute lymphoblastic leukemia (ALL)

  * No known mature B-cell ALL, defined by the presence of any of the following:

    * Surface immunoglobulin
    * L3 morphology
    * t(8;14)(q24;q32)
    * t(8;22)
    * t(2;8)
  * T-cell surface markers and t(8;14)(q24;q11) allowed
* No secondary ALL

PATIENT CHARACTERISTICS:

* No known HIV positivity
* Not pregnant or nursing
* Fertile patients must use effective contraception

PRIOR CONCURRENT THERAPY:

* No prior therapy except steroids of ≤ 1 week in duration and/or emergent radiation therapy to the mediastinum

  * Patients treated with steroids within the past 7 days will not receive steroid prophase during study treatment

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Ultrasound vs Palpation for Radial Artery Cannulation in Patients Undergoing Bariatic Surgery
Brief Summary: The primary purpose of this study is to compare the palpation technique with ultrasound guidance for radial artery cannulation for bariatic surgery.


Options:
A: Inclusion Criteria:

1. Age ≥ 18 years.
2. The distal and proximal radial artery must be palpable and non-occlusive flow must be confirmed by (Doppler) ultrasound.
3. Patient should be able to comply with the protocol.
4. Provide written informed consent before study participation

Exclusion Criteria:

1. Obligatory femoral or forearm radial access
2. Previous ipsilateral forearm radial artery occlusion.
3. Patient on therapeutic oral anticoagulation.
4. Very large hand/wrist anatomy that will preclude using the available hemostatic radial bands.
5. Enrolment in another study that competes or interferes with this study.
6. Poor clinical condition like cardiogenic shock, which prohibits pre- and post-procedural function tests.
7. Subject with planned complex PCI or procedure necessitating multiple intervention.
8. Any other condition or co-morbidity which, in the opinion of the investigator or operator, may pose a significant hazard to the subject if he or she is enrolled in the study.
9. History of stroke with residual deficit that affects hand function.
10. Previous radial artery catheterization within 1 year.
B: Inclusion Criteria:

* all patients with clear indication to radial artery catheterization like hemodynamic instability or the need of frequent arterial samples

Exclusion Criteria:

* refusal, Peripheral arterial diseases
C: Inclusion Criteria:

* All adult Patients worthy of radial artery cannulation, who consented

Exclusion Criteria:

* No consent
D: Inclusion Criteria:

* American Society of Anesthesiologists 1, 2, 3 BMI ≥ 30 bariatic surgery

Exclusion Criteria:

* refusal infection or surgery history in wrist

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Ultrasound vs Palpation for Radial Artery Cannulation in Patients Undergoing Bariatic Surgery
Brief Summary: The primary purpose of this study is to compare the palpation technique with ultrasound guidance for radial artery cannulation for bariatic surgery.


Options:
A: Inclusion Criteria:

1. Age ≥ 18 years.
2. The distal and proximal radial artery must be palpable and non-occlusive flow must be confirmed by (Doppler) ultrasound.
3. Patient should be able to comply with the protocol.
4. Provide written informed consent before study participation

Exclusion Criteria:

1. Obligatory femoral or forearm radial access
2. Previous ipsilateral forearm radial artery occlusion.
3. Patient on therapeutic oral anticoagulation.
4. Very large hand/wrist anatomy that will preclude using the available hemostatic radial bands.
5. Enrolment in another study that competes or interferes with this study.
6. Poor clinical condition like cardiogenic shock, which prohibits pre- and post-procedural function tests.
7. Subject with planned complex PCI or procedure necessitating multiple intervention.
8. Any other condition or co-morbidity which, in the opinion of the investigator or operator, may pose a significant hazard to the subject if he or she is enrolled in the study.
9. History of stroke with residual deficit that affects hand function.
10. Previous radial artery catheterization within 1 year.
B: Inclusion Criteria:

* Admission of the first degree relatives of the patients and if the patient can give consent
* Patients over 18
* Non-pregnant patients
* Patients without inotropic/vasopressor support
* Patients who do not have contraindications for radial artery cannulation (thrombosis in the distal region, a focus of infection at the site of entry, lack of adequate collateral flow in the Allen test, peripheral vascular diseases \[eg, Raynaud's disease)\]

Exclusion Criteria:

* Patient/Patient's first degree relatives refuse to work
* Patients under 18
* Pregnant patients
* Patients with contraindications for radial artery cannulation (thrombosis in the distal region, a focus of infection at the site of entry, lack of adequate collateral flow in the Allen test, peripheral vascular diseases \[eg, Raynaud's disease)\]
* Patient's inotropic/vasopressor support
C: Inclusion Criteria:

* Elective cardiovascular surgery where RA catheterization is newly required.

Exclusion Criteria:

* skin infection or trauma
* Bilateral arteriovenous fistula for dialysis
* Severe peripheral vascular disease
* Severe arteriosclerosis or arterial atheroma
* Raynaud disease
* Shock
* Patients on ECMO or IABP support
* Morbid obesity
* Profound coagulopathy
* Negative results of modified Allen's test
D: Inclusion Criteria:

* American Society of Anesthesiologists 1, 2, 3 BMI ≥ 30 bariatic surgery

Exclusion Criteria:

* refusal infection or surgery history in wrist

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Ultrasound vs Palpation for Radial Artery Cannulation in Patients Undergoing Bariatic Surgery
Brief Summary: The primary purpose of this study is to compare the palpation technique with ultrasound guidance for radial artery cannulation for bariatic surgery.


Options:
A: Inclusion Criteria:

* Surgery under general anesthesia
* Requires invasive arterial blood pressure monitoring

Exclusion Criteria:

* Infection/hematoma/skin disease/arteriovenous fistula/recent catheterization scar in radial artery or posterior tibial artery
* Peripheral vascular disease
* Congenital aortic disease
B: Inclusion Criteria:

* Adult patients presenting for cardiac or peripheral catheterization with planned radial approach.
* Barbeau's or Allen's test indicating at least some degree of collateral circulation in palmar vessels
* Functional ultrasound equipment with ultrasound trained attending operator

Exclusion Criteria:

* Inability to provide informed consent
* Femoral access
* Emergency procedure (Shock, STEMI)
* End-stage renal disease on hemodialysis
* Previous ipsilateral puncture within 1 week
C: Inclusion Criteria:

* Patients undergoing cardiac surgery
* Age 19 or older
* Provided written informed consent

Exclusion Criteria:

* Suspected inability to comply with study procedures, including language difficulties or medical history and/or concomitant disease, as judged by the investigator
* Previous surgery at the site of proposed radial artery catheterization
* Any vascular condition that may preclude eligibility for radial artery line insertion as judged by the investigator
* Patients with ventricular assist devices
* Previous inclusion in this study
D: Inclusion Criteria:

* American Society of Anesthesiologists 1, 2, 3 BMI ≥ 30 bariatic surgery

Exclusion Criteria:

* refusal infection or surgery history in wrist

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Comparison of the Efficacy of Radial Artery Catheterization in Three Different Regions in Intensive Care Patients
Brief Summary: In this prospective, randomized, open-labeled study, the intensive care patients will be selected for ultrasound-guided cannulation of the radial artery in three different regions. Patients will be divided into three groups with simple randomization. The first group will be determined as 'G1' and the radial artery catheterization with ultrasound-guided short axis out of plane intervention will be performed over 2 cm of the wrist for this group. On the second group (G2), radial artery catheterization will be performed in the distal 3/4 area of the forearm with ultrasound-guided short axis out of plane intervention. On the third group (G3), radial arterial catheterization will be performed in the distal 1/2 area of the forearm with ultrasound-guided short axis out of plane interference. Whether there is a difference in the duration of use of arterial cannula, first entry success rates, duration of intervention, number of procedures, the number of cannulas used and the effects on early and late complications and advantages between the groups will be investigated.


Options:
A: Inclusion Criteria:

* All adult Patients worthy of radial artery cannulation, who consented

Exclusion Criteria:

* No consent
B: Inclusion Criteria:

* Admission of the first degree relatives of the patients and if the patient can give consent
* Patients over 18
* Non-pregnant patients
* Patients without inotropic/vasopressor support
* Patients who do not have contraindications for radial artery cannulation (thrombosis in the distal region, a focus of infection at the site of entry, lack of adequate collateral flow in the Allen test, peripheral vascular diseases \[eg, Raynaud's disease)\]

Exclusion Criteria:

* Patient/Patient's first degree relatives refuse to work
* Patients under 18
* Pregnant patients
* Patients with contraindications for radial artery cannulation (thrombosis in the distal region, a focus of infection at the site of entry, lack of adequate collateral flow in the Allen test, peripheral vascular diseases \[eg, Raynaud's disease)\]
* Patient's inotropic/vasopressor support
C: Inclusion Criteria:

1. Patient referred for coronary angiography or percutaneous coronary intervention (PCI) in whom femoral access is planned.
2. Planned femoral access

Exclusion Criteria:

1. Age ≤ 18 years
2. STEMI
3. Absence of palpable femoral pulse
D: Inclusion Criteria:

* Adult patients presenting for cardiac or peripheral catheterization with planned radial approach.
* Barbeau's or Allen's test indicating at least some degree of collateral circulation in palmar vessels
* Functional ultrasound equipment with ultrasound trained attending operator

Exclusion Criteria:

* Inability to provide informed consent
* Femoral access
* Emergency procedure (Shock, STEMI)
* End-stage renal disease on hemodialysis
* Previous ipsilateral puncture within 1 week

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Neuraxial Preservative Free Morphine for Normal Spontaneous Vaginal Delivery: A Prospective Double Blind Randomized Control Trial
Brief Summary: Patients presenting for normal spontaneous vaginal delivery who have a neuraxial anesthestic will be randomized to receive preservative free morphine or saline placebo after delivery.


Options:
A: Inclusion Criteria:

1. Female.
2. Being 20-34 years of age.
3. First normal, healthy showing no symptoms of disorder. No history of toxemia of pregnancy, liver disease, kidney disease and gastrointestinal bleeding during pregnancy or after participating in a research project.
4. Healthy pregnant women.
5. No postpartum hemorrhage.
6. Agrees to consent form.
7. No need to take medication regularly.
8. No smoking, no drinking alcohol during pregnancy.

Exclusion Criteria:

1. Unable to travel conveniently.
2. Allergic to modern medicine or herbal remedies.
3. Have a gallstone problem.
B: Inclusion Criteria:

* Primiparous women (delivering their first baby) over the age of 19 who have delivered vaginally at Abbotsford Regional Hospital and Cancer Centre

Exclusion Criteria:

* multiparity (women who have delivered vaginally more than once), VBAC (Vaginal Birth after Cesarean Section), active sexually transmitted infection lesions, vulvar varicosities, third and forth degree perineal tear, hematoma, retained placenta/products, substance abuse, and other medical conditions requiring frequent analgesia
C: Inclusion Criteria:

* Pregnant women in labor

Exclusion Criteria:

* Not a candidate for neuraxial anesthesia
* Patient refusal
* Allergy to morphine
* Patients with chronic pain syndromes
D: Inclusion Criteria:

* parturients following normal vaginal birth or vacuum-assisted vaginal delivery
* reporting of perineal pain equal to or greater than 3 on a 0-10 scale

Exclusion Criteria:

* parturients following cesarean section
* lack of consent to take part in the study
* parturients interested in early discharge (within 48 hours of childbirth)
* girls under 18 years of age

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: AXS-05-MDD-301: A Randomized, Double-Blind, Placebo-Controlled Trial of AXS-05 in Subjects With Major Depressive Disorder
Brief Summary: A Phase 3, randomized, double-blind, placebo-controlled, multicenter trial of AXS-05 in patients with major depressive disorder (MDD).


Options:
A: Inclusion Criteria:

1. Able to give written informed consent and comply with the study protocol.
2. An established diagnosis of bipolar disorder (either type I or II) and have had at least 3 previous episodes of illness within the previous 5 years or 2 episodes in the last 12 months.

To be eligible for inclusion, each subject must meet each of the inclusion criteria at Screening (Visit 1) and must continue to fulfil these criteria at Baseline (Visit 2).

Exclusion Criteria:

* Severity of their bipolar disorder is such that participation in a clinical trial is not appropriate because of the risk of imminent self-harm or psychiatric admission,
* A concurrent medical condition (intracranial brain lesion),
* Medication (steroids) that may be accounting for the mood episodes,
* Participant is taking omega-3 PUFA supplements at the time of study entry or in the previous 12 weeks
* Individuals who are participating in another study where they are receiving a different investigational agent during the course, or within the 12 week period prior to their inclusion in this study.
B: Key Inclusion Criteria:

* Age 18 - 65
* Currently meets DSM-5 criteria for MDD
* Body Mass Index between 18 and 40 kg/m\^2, inclusive

Key Exclusion Criteria:

* Suicide risk
* History of treatment resistance in current depressive episode
* History of electroconvulsive therapy, vagus nerve stimulation, transcranial magnetic stimulation or any experimental central nervous system treatment during the current episode or in the past 6 months
* Pregnant, breastfeeding, or planning to become pregnant or breastfeed during the study
C: Inclusion Criteria:

* Satisfy DSM-IV-TR criteria for Major Depressive Episode
* 18 years or over
* Does not have a diagnosis of schizophrenia, schizoaffective disorder, rapid cycling bipolar disorder, or current psychotic symptoms
* No known sensitivity to ketamine
* No ECT in the last 3 months
* No drug or alcohol abuse in the last 12 months
* Able to give informed consent
* Score at least 24 on Mini Mental State Examination
D: Inclusion Criteria:

* BMI 18-30 Non-smoker for at least 4 weeks

Exclusion Criteria:

* Any clinically relevant acute or chronic disease
* History of substance abuse Hypersensitivity to ketamine

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: PREMOM II: Pregnancy Remote Monitoring of Women with Gestational Hypertensive Disorders
Brief Summary: The goal of this project is thoroughly evaluate the added value of telemonitoring (TM) program for women at risk for gestational hypertensive disorders (GHD), by investigating it impact on prenatal follow-up, health outcomes for mother and child, costs and satisfaction, and by specifically investigating what are the major contributors to this added value.

A substudy (CAPROM) will be conducted at the Department of Obstetrics \& Gynecology at Ziekenhuis Oost-Limburg (ZOL) in collaboration with the Department of Physiology of Hasselt University in the framework of the Limburg Clinical Research Center (LCRC). CAPROM aims at evaluating the relationship between longitudinal (clinical) blood pressure measurements and changes in (subclinical) cardiovascular (CV) hemodynamics throughout pregnancy, as well as their responses to antihypertensive medication. To this end, CV profiling will be performed longitudinally on pregnant women at risk for developing GHD being included in the TM group of the PREMOM II study (group 1) or being followed-up via TM as part of their usual care (group 2). A separate ICF is signed for inclusion in the CAPROM substudy. The results of the CAPROM study will be performed by a researcher who is not involved in the PREMOM II main study. In addition, results of the CV profiling will not be communicated to the clinical decision makers of PREMOM II.


Options:
A: Inclusion Criteria:

* Written, signed and dated informed consent
* ≥ 18 years of age
* BMI \>40 kg/m2
* Has a clinically indicated radial artery line already in situ or who agree to placement of an arterial line
* Systolic blood pressure \>160 mm Hg
* Gestational age greater than or equal to 24 weeks
* Parturients admitted for induction of labor

Exclusion Criteria:

* Parturients admitted in labor
B: Inclusion Criteria:

* at least 5 months pregnant

Exclusion Criteria:

* Unable to provide consent.
C: Inclusion Criteria:

* women with a diagnosis of hypertension in pregnancy

Exclusion Criteria:

* non-pregnant and normotensive pregnancy women
D: Inclusion Criteria:

* a risk \> 1/100 on the Fetal Medicine Foundation (FMF) tool, which is used from the following website: https://fetalmedicine.org/research/assess/preeclampsia/first-trimester
* CAPROM substudy: Pregnant women at risk for the development of GHD being followed-up via TM as part of the PREMOM II study (group 1) or usual care (group 2)

Exclusion Criteria:

* congenital malformations of the newborn,
* pregnant women who doesn't have a Smartphone,
* pregnant women \< 18 years old,
* pregnant women who doesn't understand the Dutch/French/English language. -

Answer: D