TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Pilot Study Assessing the Feasibility of a Randomized Controlled Trial Evaluating Aspirin Versus Low-molecular-weight Heparin (LMWH) and Aspirin in Women With Antiphospholipid Syndrome and Pregnancy Loss
Brief Summary: The APPLE pilot trial is a feasibility study that is a multicentre, open-label, randomized controlled trial. Pregnant women with antiphospholipid syndrome (APS) and a history of late (≥10 weeks gestation) or recurrent early (2 \<10 weeks) pregnancy loss will be recruited.

Eligible and consenting subjects will be assigned to one of two study arms: open-label low-molecular-weight heparin (LMWH) prophylaxis until 37 weeks gestation AND low-dose aspirin (ASA) daily until delivery, or open-label low-dose aspirin daily from randomization until delivery.


Options:
A: Arm Label: Standard of Care Arm; Type: ACTIVE_COMPARATOR; Interventions: Drug: Low-molecular-weight heparin | Arm Label: Experimental Arm; Type: EXPERIMENTAL; Interventions: Drug: Aspirin 81 mg | Intervention Type: DRUG; Name: Aspirin 81 mg; Assigned to Arm(s): Experimental Arm | Intervention Type: DRUG; Name: Low-molecular-weight heparin; Assigned to Arm(s): Standard of Care Arm
B: Intervention Type: DRUG; Name: Low dose steroids; Assigned to Arm(s): N/A
C: Arm Label: Enoxaparin group; Type: ACTIVE_COMPARATOR; Interventions: Drug: Enoxaparin | Arm Label: Warfarin group; Type: ACTIVE_COMPARATOR; Interventions: Drug: Warfarin | Intervention Type: DRUG; Name: Enoxaparin; Assigned to Arm(s): Enoxaparin group | Intervention Type: DRUG; Name: Warfarin; Assigned to Arm(s): Warfarin group
D: Arm Label: enoxaparin fixed; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: enoxaparin adjusted; Type: EXPERIMENTAL; Interventions: Drug: enoxaparin | Intervention Type: DRUG; Name: enoxaparin; Assigned to Arm(s): enoxaparin adjusted

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Pilot Study Assessing the Feasibility of a Randomized Controlled Trial Evaluating Aspirin Versus Low-molecular-weight Heparin (LMWH) and Aspirin in Women With Antiphospholipid Syndrome and Pregnancy Loss
Brief Summary: The APPLE pilot trial is a feasibility study that is a multicentre, open-label, randomized controlled trial. Pregnant women with antiphospholipid syndrome (APS) and a history of late (≥10 weeks gestation) or recurrent early (2 \<10 weeks) pregnancy loss will be recruited.

Eligible and consenting subjects will be assigned to one of two study arms: open-label low-molecular-weight heparin (LMWH) prophylaxis until 37 weeks gestation AND low-dose aspirin (ASA) daily until delivery, or open-label low-dose aspirin daily from randomization until delivery.


Options:
A: Arm Label: Standard of Care Arm; Type: ACTIVE_COMPARATOR; Interventions: Drug: Low-molecular-weight heparin | Arm Label: Experimental Arm; Type: EXPERIMENTAL; Interventions: Drug: Aspirin 81 mg | Intervention Type: DRUG; Name: Aspirin 81 mg; Assigned to Arm(s): Experimental Arm | Intervention Type: DRUG; Name: Low-molecular-weight heparin; Assigned to Arm(s): Standard of Care Arm
B: Arm Label: Enoxaparin group; Type: ACTIVE_COMPARATOR; Interventions: Drug: Enoxaparin | Arm Label: Warfarin group; Type: ACTIVE_COMPARATOR; Interventions: Drug: Warfarin | Intervention Type: DRUG; Name: Enoxaparin; Assigned to Arm(s): Enoxaparin group | Intervention Type: DRUG; Name: Warfarin; Assigned to Arm(s): Warfarin group
C: Arm Label: ASA; Type: ACTIVE_COMPARATOR; Interventions: Drug: Aspirin | Arm Label: Klexane; Type: ACTIVE_COMPARATOR; Interventions: Drug: Klexane | Arm Label: Aspirin and Enoxaparine; Type: ACTIVE_COMPARATOR; Interventions: Drug: Klexane and ASA | Intervention Type: DRUG; Name: Aspirin; Assigned to Arm(s): ASA | Intervention Type: DRUG; Name: Klexane; Assigned to Arm(s): Klexane | Intervention Type: DRUG; Name: Klexane and ASA; Assigned to Arm(s): Aspirin and Enoxaparine
D: Arm Label: enoxaparin 40 mg plus low dose aspirin; Type: EXPERIMENTAL; Interventions: Drug: enoxaparin 40mg plus low dose aspirin | Arm Label: Heparin calcium 5,000 U twice daily plus low dose aspirin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Heparin calcium5,000 U twice daily plus low dose aspirin | Intervention Type: DRUG; Name: enoxaparin 40mg plus low dose aspirin; Assigned to Arm(s): enoxaparin 40 mg plus low dose aspirin | Intervention Type: DRUG; Name: Heparin calcium5,000 U twice daily plus low dose aspirin; Assigned to Arm(s): Heparin calcium 5,000 U twice daily plus low dose aspirin

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Pilot Study Assessing the Feasibility of a Randomized Controlled Trial Evaluating Aspirin Versus Low-molecular-weight Heparin (LMWH) and Aspirin in Women With Antiphospholipid Syndrome and Pregnancy Loss
Brief Summary: The APPLE pilot trial is a feasibility study that is a multicentre, open-label, randomized controlled trial. Pregnant women with antiphospholipid syndrome (APS) and a history of late (≥10 weeks gestation) or recurrent early (2 \<10 weeks) pregnancy loss will be recruited.

Eligible and consenting subjects will be assigned to one of two study arms: open-label low-molecular-weight heparin (LMWH) prophylaxis until 37 weeks gestation AND low-dose aspirin (ASA) daily until delivery, or open-label low-dose aspirin daily from randomization until delivery.


Options:
A: Arm Label: Standard of Care Arm; Type: ACTIVE_COMPARATOR; Interventions: Drug: Low-molecular-weight heparin | Arm Label: Experimental Arm; Type: EXPERIMENTAL; Interventions: Drug: Aspirin 81 mg | Intervention Type: DRUG; Name: Aspirin 81 mg; Assigned to Arm(s): Experimental Arm | Intervention Type: DRUG; Name: Low-molecular-weight heparin; Assigned to Arm(s): Standard of Care Arm
B: Arm Label: enoxaparin 40 mg plus low dose aspirin; Type: EXPERIMENTAL; Interventions: Drug: enoxaparin 40mg plus low dose aspirin | Arm Label: Heparin calcium 5,000 U twice daily plus low dose aspirin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Heparin calcium5,000 U twice daily plus low dose aspirin | Intervention Type: DRUG; Name: enoxaparin 40mg plus low dose aspirin; Assigned to Arm(s): enoxaparin 40 mg plus low dose aspirin | Intervention Type: DRUG; Name: Heparin calcium5,000 U twice daily plus low dose aspirin; Assigned to Arm(s): Heparin calcium 5,000 U twice daily plus low dose aspirin
C: Arm Label: ASA; Type: ACTIVE_COMPARATOR; Interventions: Drug: Aspirin | Arm Label: Klexane; Type: ACTIVE_COMPARATOR; Interventions: Drug: Klexane | Arm Label: Aspirin and Enoxaparine; Type: ACTIVE_COMPARATOR; Interventions: Drug: Klexane and ASA | Intervention Type: DRUG; Name: Aspirin; Assigned to Arm(s): ASA | Intervention Type: DRUG; Name: Klexane; Assigned to Arm(s): Klexane | Intervention Type: DRUG; Name: Klexane and ASA; Assigned to Arm(s): Aspirin and Enoxaparine
D: Arm Label: Group A(heparin group); Type: ACTIVE_COMPARATOR; Interventions: Drug: Heparin | Arm Label: Group B; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: Heparin; Assigned to Arm(s): Group A(heparin group)

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Robotic-assisted Training After Upper Arm Fracture - a Multicentre, Controlled and Randomized Intervention Study
Brief Summary: In this study, patients with upper arm fracture will receive an additive robotic-assisted training using the Armeo®Spring robot for three weeks on the injured arm in addition to conventional physio- and occupational therapy. The supportive treatment and execution of specific exercises on the Armeo®Spring should lead to improved recovery of function and mobility of the upper arm compared to conservatively treated patients.


Options:
A: Arm Label: Conservative /Physiotherapy; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Surgery with LCP T plate; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Surgical treatment with LCP | Intervention Type: PROCEDURE; Name: Surgical treatment with LCP; Assigned to Arm(s): Surgery with LCP T plate
B: Arm Label: Operative treatment; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Operative treatment with Reversed Total Shoulder Prosthesis | Arm Label: Non-Operative treatment; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: PROCEDURE; Name: Operative treatment with Reversed Total Shoulder Prosthesis; Assigned to Arm(s): Operative treatment
C: Arm Label: Angular stable plate Philos; Type: ACTIVE_COMPARATOR; Interventions: Device: Reverse total shoulder arthroplasty | Arm Label: Reverse Total Shoulder Artroplasty; Type: EXPERIMENTAL; Interventions: Device: Reverse total shoulder arthroplasty | Intervention Type: DEVICE; Name: Reverse total shoulder arthroplasty; Assigned to Arm(s): Angular stable plate Philos, Reverse Total Shoulder Artroplasty
D: Arm Label: Intervention Armeo®Spring; Type: ACTIVE_COMPARATOR; Interventions: Other: Intervention Armeo®Spring | Arm Label: Control group; Type: ACTIVE_COMPARATOR; Interventions: Other: Control Group | Intervention Type: OTHER; Name: Intervention Armeo®Spring; Assigned to Arm(s): Intervention Armeo®Spring | Intervention Type: OTHER; Name: Control Group; Assigned to Arm(s): Control group

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Patient Aligned Care Team (PACT) Intensive Management (PIM) Project
Brief Summary: Purpose: Implement a Patient Aligned Care Team (PACT) model that identifies and proactively manages Veterans at the highest risk for hospital admission and death while the patient is still in the ambulatory care setting.

Goal:

* Reduce emergency department and urgent care utilization, hospitalization, and mortality in complex, high risk patients
* Improve Veteran and staff satisfaction

Objectives:

* Maintain the patient in the home setting as much as possible
* Secure appropriate home environment to facilitate health and well-being
* Utilize comprehensive team-based care
* Engage appropriate Veteran Health Administration (VHA) programs to provide interdisciplinary, coordinated, and timely management of complex medical issues


Options:
A: Arm Label: Usual Care; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Usual care | Arm Label: Counseling; Type: EXPERIMENTAL; Interventions: Behavioral: physical activity counseling | Intervention Type: BEHAVIORAL; Name: physical activity counseling; Assigned to Arm(s): Counseling | Intervention Type: BEHAVIORAL; Name: Usual care; Assigned to Arm(s): Usual Care
B: Arm Label: Usual care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Coaching program; Type: EXPERIMENTAL; Interventions: Other: Coaching program | Intervention Type: OTHER; Name: Coaching program; Assigned to Arm(s): Coaching program
C: Arm Label: Intervention--PACT Intensive Management; Type: EXPERIMENTAL; Interventions: Behavioral: PACT Intensive Management | Arm Label: Usual care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: PACT Intensive Management; Assigned to Arm(s): Intervention--PACT Intensive Management
D: Arm Label: Group 1; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Group 2; Type: EXPERIMENTAL; Interventions: Behavioral: COPD Self-management Education | Intervention Type: BEHAVIORAL; Name: COPD Self-management Education; Assigned to Arm(s): Group 2

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Early Initiation of Extracorporeal Life Support in Refractory OHCA (INCEPTION)
Brief Summary: Despite adequate conventional cardiopulmonary resuscitation (CCPR) and attempted defibrillation, a considerable number of patients in cardiac arrest fail to achieve sustained return of spontaneous circulation. The INCEPTION trial is a multicenter, randomized controlled trial that will explore extracorporeal cardiopulmonary resuscitation (ECPR) in patients in refractory out-of-hospital cardiac arrest (OHCA) presenting with ventricular fibrillation or tachycardia. It aims to determine the effect on survival and neurological outcome. Additionally, it will evaluate the feasibility and cost-effectiveness of ECPR.


Options:
A: Arm Label: CCPR protocol; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: ECPR protocol; Type: EXPERIMENTAL; Interventions: Procedure: Extracorporeal cardiopulmonary resuscitation (ECPR) | Intervention Type: PROCEDURE; Name: Extracorporeal cardiopulmonary resuscitation (ECPR); Assigned to Arm(s): ECPR protocol
B: Arm Label: One single arm; Type: EXPERIMENTAL; Interventions: Device: ECCO2R will be initiated during the 2-hour run-in time, Other: Neuromuscular blocking agents (NMBA), Device: Ventilation, Other: Level of carbon dioxide released at the end of expiration, Other: Respiratory Rate, Other: Sweep gas flow, Other: Ventilation will be adapted, Other: Respiratory rate will be adapted | Intervention Type: DEVICE; Name: ECCO2R will be initiated during the 2-hour run-in time; Assigned to Arm(s): One single arm | Intervention Type: OTHER; Name: Neuromuscular blocking agents (NMBA); Assigned to Arm(s): One single arm | Intervention Type: DEVICE; Name: Ventilation; Assigned to Arm(s): One single arm | Intervention Type: OTHER; Name: Level of carbon dioxide released at the end of expiration; Assigned to Arm(s): One single arm | Intervention Type: OTHER; Name: Respiratory Rate; Assigned to Arm(s): One single arm | Intervention Type: OTHER; Name: Sweep gas flow; Assigned to Arm(s): One single arm | Intervention Type: OTHER; Name: Ventilation will be adapted; Assigned to Arm(s): One single arm | Intervention Type: OTHER; Name: Respiratory rate will be adapted; Assigned to Arm(s): One single arm
C: Arm Label: One Group; Type: N/A; Interventions: N/A
D: Arm Label: Moderate hypothermia; Type: EXPERIMENTAL; Interventions: Other: moderate hypothermia | Arm Label: Normothermia; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: moderate hypothermia; Assigned to Arm(s): Moderate hypothermia

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Early Initiation of Extracorporeal Life Support in Refractory OHCA (INCEPTION)
Brief Summary: Despite adequate conventional cardiopulmonary resuscitation (CCPR) and attempted defibrillation, a considerable number of patients in cardiac arrest fail to achieve sustained return of spontaneous circulation. The INCEPTION trial is a multicenter, randomized controlled trial that will explore extracorporeal cardiopulmonary resuscitation (ECPR) in patients in refractory out-of-hospital cardiac arrest (OHCA) presenting with ventricular fibrillation or tachycardia. It aims to determine the effect on survival and neurological outcome. Additionally, it will evaluate the feasibility and cost-effectiveness of ECPR.


Options:
A: Arm Label: CCPR protocol; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: ECPR protocol; Type: EXPERIMENTAL; Interventions: Procedure: Extracorporeal cardiopulmonary resuscitation (ECPR) | Intervention Type: PROCEDURE; Name: Extracorporeal cardiopulmonary resuscitation (ECPR); Assigned to Arm(s): ECPR protocol
B: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Device: Intraaortic Balloon Pump | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Device: Left Ventricular Assist Device Impella LP 2.5 | Intervention Type: DEVICE; Name: Left Ventricular Assist Device Impella LP 2.5; Assigned to Arm(s): 2 | Intervention Type: DEVICE; Name: Intraaortic Balloon Pump; Assigned to Arm(s): 1
C: Arm Label: Treatment; Type: EXPERIMENTAL; Interventions: Device: HeartNet Ventricular Support System | Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Drug: Optimal Medical/Device Therapy | Intervention Type: DEVICE; Name: HeartNet Ventricular Support System; Assigned to Arm(s): Treatment | Intervention Type: DRUG; Name: Optimal Medical/Device Therapy; Assigned to Arm(s): Control
D: Arm Label: Conventional circulatory support; Type: PLACEBO_COMPARATOR; Interventions: Device: Conventional circulatory support | Arm Label: Impella; Type: ACTIVE_COMPARATOR; Interventions: Device: Impella CP | Intervention Type: DEVICE; Name: Conventional circulatory support; Assigned to Arm(s): Conventional circulatory support | Intervention Type: DEVICE; Name: Impella CP; Assigned to Arm(s): Impella

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: HeartHab: a Prospective Cross-over Trial Investigating the Effectiveness of an App Based Telerehabilitation Program on Exercise Capacity, Lifestyle and Risk Factors in Patients With Coronary Artery Disease
Brief Summary: The recurrence of major cardiac events after infarction is very high, in some populations up to 20% in the first year. Optimal secondary prevention as organized in cardiac rehabilitation centers is effective in reducing both morbidity and mortality. However, many studies have shown that the participation and adherence rate in CR-programs is low in most European countries. Therefore, novel ways of delivering secondary prevention using information technology and self-monitoring are being explored. Hence, this study will investigate the effectiveness of a mobile, patient tailored, app based multidisciplinary telerehabilitation program (HeartHab app) in improving exercise capacity, lifestyle and risk factors in patients with coronary artery disease in a post-rehabilitation setting.


Options:
A: Arm Label: Self Monitoring of Software Application; Type: OTHER; Interventions: Device: Self Monitoring Software Application | Arm Label: No Intervention; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: Self Monitoring Software Application; Assigned to Arm(s): Self Monitoring of Software Application
B: Arm Label: Treadmill group; Type: ACTIVE_COMPARATOR; Interventions: Other: Exercise training | Arm Label: Exercise groups; Type: ACTIVE_COMPARATOR; Interventions: Other: Exercise training | Arm Label: home-based exercise; Type: ACTIVE_COMPARATOR; Interventions: Other: Exercise training | Intervention Type: OTHER; Name: Exercise training; Assigned to Arm(s): Exercise groups, Treadmill group, home-based exercise
C: Arm Label: AB sequence; Type: EXPERIMENTAL; Interventions: Other: Usual care followed by the use of HeartHab application | Arm Label: BA sequence; Type: EXPERIMENTAL; Interventions: Other: Use of HeartHab application followed by usual care | Intervention Type: OTHER; Name: Use of HeartHab application followed by usual care; Assigned to Arm(s): BA sequence | Intervention Type: OTHER; Name: Usual care followed by the use of HeartHab application; Assigned to Arm(s): AB sequence
D: Arm Label: Telerehabilitation group; Type: EXPERIMENTAL; Interventions: Other: Telerehabilitation group | Arm Label: Centre - based rehabilitation group; Type: ACTIVE_COMPARATOR; Interventions: Other: Centre - based rehabilitation group | Arm Label: Usual care group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Telerehabilitation group; Assigned to Arm(s): Telerehabilitation group | Intervention Type: OTHER; Name: Centre - based rehabilitation group; Assigned to Arm(s): Centre - based rehabilitation group

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: HeartHab: a Prospective Cross-over Trial Investigating the Effectiveness of an App Based Telerehabilitation Program on Exercise Capacity, Lifestyle and Risk Factors in Patients With Coronary Artery Disease
Brief Summary: The recurrence of major cardiac events after infarction is very high, in some populations up to 20% in the first year. Optimal secondary prevention as organized in cardiac rehabilitation centers is effective in reducing both morbidity and mortality. However, many studies have shown that the participation and adherence rate in CR-programs is low in most European countries. Therefore, novel ways of delivering secondary prevention using information technology and self-monitoring are being explored. Hence, this study will investigate the effectiveness of a mobile, patient tailored, app based multidisciplinary telerehabilitation program (HeartHab app) in improving exercise capacity, lifestyle and risk factors in patients with coronary artery disease in a post-rehabilitation setting.


Options:
A: Arm Label: OPTICARE-A; Type: EXPERIMENTAL; Interventions: Other: rehabilitation+telephonic coaching | Arm Label: OPTICARE-B; Type: ACTIVE_COMPARATOR; Interventions: Other: OPTICARE-B | Arm Label: OPTICARE-C; Type: EXPERIMENTAL; Interventions: Other: OPTICARE-C | Intervention Type: OTHER; Name: rehabilitation+telephonic coaching; Assigned to Arm(s): OPTICARE-A | Intervention Type: OTHER; Name: OPTICARE-B; Assigned to Arm(s): OPTICARE-B | Intervention Type: OTHER; Name: OPTICARE-C; Assigned to Arm(s): OPTICARE-C
B: Arm Label: Extended behavioral intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Extended behavioral intervention | Arm Label: Usual care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Extended behavioral intervention; Assigned to Arm(s): Extended behavioral intervention
C: Arm Label: Exercise; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Exercise; Assigned to Arm(s): Exercise
D: Arm Label: AB sequence; Type: EXPERIMENTAL; Interventions: Other: Usual care followed by the use of HeartHab application | Arm Label: BA sequence; Type: EXPERIMENTAL; Interventions: Other: Use of HeartHab application followed by usual care | Intervention Type: OTHER; Name: Use of HeartHab application followed by usual care; Assigned to Arm(s): BA sequence | Intervention Type: OTHER; Name: Usual care followed by the use of HeartHab application; Assigned to Arm(s): AB sequence

Answer: D