Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Early Salvage With High Dose Chemotherapy and Stem Cell Transplantation in Advanced Stage Hodgkin's Lymphoma Patients With Positive PET After Two Courses of ABVD (PET-2 Positive) and Comparison of RT Versus no RT in PET-2 Negative Patients
Brief Summary: The purpose of this study is to define an improvement in patients:

* To evaluate if patients resistant to the initial treatment for residual PET-positive masses after the first two courses of ABVD (PET-2 positive), can be salvaged by early shift to high-dose chemotherapy supported by stem cell rescue
* To analyse if patients achieving early complete response (PET-2 negative), can be spared the adjuvant radiotherapy on areas of initial bulky disease, at the end of the planned six courses of ABVD. To answer this question, PET-2 negative patients will be randomized between radiotherapy versus no radiotherapy at the end of ABVD therapy.


Options:
A: Arm Label: Treatment (chemotherapy and F-18 PET/CT); Type: EXPERIMENTAL; Interventions: Biological: Bleomycin Sulfate, Drug: Doxorubicin Hydrochloride, Drug: Procarbazine Hydrochloride, Drug: Vinblastine Sulfate, Drug: Dacarbazine, Drug: Cyclophosphamide, Drug: Etoposide phosphate, Drug: prednisone, Drug: Radiation Therapy, Radiation: Fludeoxyglucose F-18, Procedure: computed tomography, Procedure: Positron Emission Tomography | Intervention Type: BIOLOGICAL; Name: Bleomycin Sulfate; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: Doxorubicin Hydrochloride; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: Procarbazine Hydrochloride; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: Vinblastine Sulfate; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: Dacarbazine; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: Cyclophosphamide; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: Etoposide phosphate; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: prednisone; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: DRUG; Name: Radiation Therapy; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: RADIATION; Name: Fludeoxyglucose F-18; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: PROCEDURE; Name: computed tomography; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT) | Intervention Type: PROCEDURE; Name: Positron Emission Tomography; Assigned to Arm(s): Treatment (chemotherapy and F-18 PET/CT)
B: Arm Label: Arm I; Type: ACTIVE_COMPARATOR; Interventions: Radiation: Involved Field Radiotherapy | Arm Label: Arm II; Type: EXPERIMENTAL; Interventions: Other: No further treatment | Intervention Type: RADIATION; Name: Involved Field Radiotherapy; Assigned to Arm(s): Arm I | Intervention Type: OTHER; Name: No further treatment; Assigned to Arm(s): Arm II
C: Arm Label: PET pos; Type: EXPERIMENTAL; Interventions: Drug: ESCALATED BEACOPP | Arm Label: PET negative; Type: OTHER; Interventions: Drug: CONVENTIONAL ABVD | Intervention Type: DRUG; Name: ESCALATED BEACOPP; Assigned to Arm(s): PET pos | Intervention Type: DRUG; Name: CONVENTIONAL ABVD; Assigned to Arm(s): PET negative
D: Arm Label: Arm A; Type: OTHER; Interventions: Drug: ABVD | Arm Label: Arm B; Type: OTHER; Interventions: Drug: ABVD and Radiotherapy | Intervention Type: DRUG; Name: ABVD; Assigned to Arm(s): Arm A | Intervention Type: DRUG; Name: ABVD and Radiotherapy; Assigned to Arm(s): Arm B

Answer: D