TrialPanorama/Dataset huggingface dataset:
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Brief Admission Skane: Can Brief Admission Replace General Admission for Individuals With Self-harm and Acute Risk of Suicide
Brief Summary: The purpose of the study is to test a standardized version of brief admission (BA) through randomized controlled trial (RCT). The main objective is to evaluate if BA can serve as a crisis management model for individuals with recurrent self-harm, including suicide attempts and at least three symptoms of Borderline Personality disorder. Participants will be allocated to BA + Treatment as Usual (TAU) or TAU.


Options:
A: Inclusion Criteria:

* An episode of self harm within 48 hours before being admitted at the department;

  * age of 16 to 64 years;
  * Resident in the trial site catchments area,
  * Ability to complete a baseline assessment;
  * Ability to provide at least 2 verifiable contacts to improve tracking for subsequent assessments; and ability to understand and provide informed consent.

Exclusion Criteria:

* • A medical disorder that would prevent participation in an outpatient clinical trial.

  * Temporary resident unlikely to be available for follow up.
  * Diagnosis of Alcohol and other drug dependence, schizophrenia or Bipolar Disorders.
B: Inclusion Criteria:

* Current episodes of self-harm and/or recurrent suicidality.
* Fulfilling at least three criteria for borderline personality disorder.
* Admitted to psychiatric hospital for acute care for at least 7 days or presenting to the psychiatric emergency department at least 3 times during the last six months.

Exclusion Criteria:

* No regular contact with outpatient psychiatric services.
* Homelessness. Housing crises are outside the scope of this RCT.
* Medical disorder from other organs that significantly contributes to inclusion criteria (e.g. if self-harm only occurs during episodes of hypoglycemia in a diabetic patient).
C: Inclusion Criteria:

* Ages 12 to18 years
* Youth presenting in the Emergency Department with acute suicidal ideation or suicide risk behaviour
* SIQ-Jr score ≥ 31
* Parent or caregiver able to communicate in English, or is willing to communicate using a hospital-organized translator, and willing to participate in study
* Living in the greater Toronto area and access to a telephone.

Exclusion Criteria:

* Active psychosis or hypomania/mania
* Moderate to severe intellectual disability, autism.
D: Inclusion Criteria:

* age ≥ 18 years
* DSM-IV-TR diagnoses of BPD and PTSD
* legal competence
* none or stable medication
* illegal drug abstinence for at least the last 6 months
* capacity to consent and contract

Exclusion Criteria:

* other severe mental disorders (e.g., bipolar disorder, acute psychosis)
* simultaneous consumption of drugs
* simultaneous participation in other treatment-studies
* pregnancy or breastfeeding
* lack of capability to negotiate a no-suicide agreement
* suicide attempt or attempts during the 8 weeks prior to start of treatment
* perpetrator-contact
* Body Mass Index (BMI) \< 16

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Brief Admission Skane: Can Brief Admission Replace General Admission for Individuals With Self-harm and Acute Risk of Suicide
Brief Summary: The purpose of the study is to test a standardized version of brief admission (BA) through randomized controlled trial (RCT). The main objective is to evaluate if BA can serve as a crisis management model for individuals with recurrent self-harm, including suicide attempts and at least three symptoms of Borderline Personality disorder. Participants will be allocated to BA + Treatment as Usual (TAU) or TAU.


Options:
A: Inclusion Criteria:

* Current episodes of self-harm and/or recurrent suicidality.
* Fulfilling at least three criteria for borderline personality disorder.
* Admitted to psychiatric hospital for acute care for at least 7 days or presenting to the psychiatric emergency department at least 3 times during the last six months.

Exclusion Criteria:

* No regular contact with outpatient psychiatric services.
* Homelessness. Housing crises are outside the scope of this RCT.
* Medical disorder from other organs that significantly contributes to inclusion criteria (e.g. if self-harm only occurs during episodes of hypoglycemia in a diabetic patient).
B: Inclusion Criteria:

* 18-65 years of age.
* Newly suicide attempt within one month of the inclusion date.
* A minimum of two characteristics in the DSM-IV Borderline Personality Disorder (BPD)
* Informed consent.

Exclusion Criteria:

* Severe depression.
* Bipolar disorder.
* Psychosis within the schizophrenic spectrum.
* Anorexia Nervosa.
* Substance abuse.
* Mental retardation.
* Dementia.
* Lack of informed consent
C: Inclusion Criteria:

* ≥ 5 nonsuicidal self-injury episodes past year
* ≥ 1 nonsuicidal self-injury episodes past month
* having at least one parent who committed to participate in the parent program

Exclusion Criteria:

* Severe suicidal ideation
* a diagnosis of psychotic or bipolar I disorder or ongoing (past month) substance dependence
* the presence of co-occurring psychological disorders that required immediate treatment (i.e., severe anorexia nervosa)
* insufficient understanding of the Swedish language
D: Inclusion Criteria:

* Active duty military
* 18 years or older
* Current suicidal ideation with intent to die and/or suicide attempt within past month
* Able to complete informed consent procedures

Exclusion Criteria:

* Psychiatric or medical condition that precludes informed consent or outpatient therapy

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Brief Admission Skane: Can Brief Admission Replace General Admission for Individuals With Self-harm and Acute Risk of Suicide
Brief Summary: The purpose of the study is to test a standardized version of brief admission (BA) through randomized controlled trial (RCT). The main objective is to evaluate if BA can serve as a crisis management model for individuals with recurrent self-harm, including suicide attempts and at least three symptoms of Borderline Personality disorder. Participants will be allocated to BA + Treatment as Usual (TAU) or TAU.


Options:
A: Inclusion Criteria:

* DSM-IV Borderline Personality Disorder;
* between 18 and 65 yrs of age

Exclusion Criteria:

* DSM-IV psychotic disorders,
* mental retardation,
* substance abuse in the forefront
B: Inclusion Criteria:

* 18-65 years of age.
* Newly suicide attempt within one month of the inclusion date.
* A minimum of two characteristics in the DSM-IV Borderline Personality Disorder (BPD)
* Informed consent.

Exclusion Criteria:

* Severe depression.
* Bipolar disorder.
* Psychosis within the schizophrenic spectrum.
* Anorexia Nervosa.
* Substance abuse.
* Mental retardation.
* Dementia.
* Lack of informed consent
C: In phase I

Inclusion Criteria:

1. With self-harm experience in the past month
2. Aged 20 years or over

Exclusion Criteria:

1. With severe hallucinations or delusions or medically unfit for interview
2. Limited hands movement (e.g. seriously wounded wrists)

In phase II

Inclusion Criteria:

1. Admitted to the ER following an episode of self-harm
2. Aged 20 years or over

Exclusion Criteria:

1. With severe hallucinations or delusions or medically unfit for interview
2. Limited hands movement (e.g. seriously wounded wrists)
D: Inclusion Criteria:

* Current episodes of self-harm and/or recurrent suicidality.
* Fulfilling at least three criteria for borderline personality disorder.
* Admitted to psychiatric hospital for acute care for at least 7 days or presenting to the psychiatric emergency department at least 3 times during the last six months.

Exclusion Criteria:

* No regular contact with outpatient psychiatric services.
* Homelessness. Housing crises are outside the scope of this RCT.
* Medical disorder from other organs that significantly contributes to inclusion criteria (e.g. if self-harm only occurs during episodes of hypoglycemia in a diabetic patient).

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Harvest for Health in Older Cancer Survivors
Brief Summary: Gardening interventions yield a multitude of measurable benefits that are evaluable within the context of a clinical trial. Harvest for Health forges new inroads in the delivery of holistic interventions to high risk populations, in this case, older cancer survivors. Since the intervention banks on an existing organization's infrastructure, it can easily be disseminated nationwide. The next step is to prove efficacy - an essential step in contributing to the science in this area, and one which is crucial for future dissemination.


Options:
A: Inclusion Criteria:

* Self-reported age ≥ 25
* Self identify as having at least one of their four grandparents as Ashkenazi Jewish
* Has medical insurance
* Able to understand and read the English-language
* Zip code falls within the catchment areas of the phase of the study (e.g. New York City, Boston, Philadelphia, Los Angeles) accessible to a BFOR designated provider

Exclusion Criteria:

* Under age 25
* No Ashkenazi Jewish ancestry
* Does not have insurance
* Has previously had medical BRCA testing ordered by a health care provider
B: Inclusion Criteria:

* Aged 15 or above
* Cantonese or Mandarin speakers

Exclusion Criteria:

* Unable to provide a consent form
* Speak language other than Cantonese and Mandarin
C: Inclusion Criteria:

* Residence in the following counties in Alabama: Autauga, Baldwin, Blount, Calhoun, Cherokee, Chilton, Coffee, Cullman, Dale, Dekalb, Elmore, Etowah. Houston, Jackson, Jefferson, Lauderdale, Lee, Limestone, Madison, Marshall, Mobile, Morgan, Montgomery, Pike, Randolph, Shelby, St. Clair, Tallapoosa, Tuscaloosa, Walker
* Diagnosed with one of the following cancers and completed primary treatment: localized larynx, gastric cardia, or cervix; localized or regionally-staged bladder, colorectum, fallopian tube, breast (female only), kidney and renal, melanoma, oral cavity, ovary, pharynx, prostate, soft tissue sarcoma, thyroid or uterus; or all stages: Hodgkin or Non-Hodgkin Lymphoma, Leukemia (CML CLL ALL) or testis.
* has at least one physical function limitation as measured by the SF-36 physical function subscale.

Exclusion Criteria:

* Currently tends an in-ground vegetable garden year round.
* Currently eats at least 2.5 cups of fruits and vegetable/day
* Currently obtains 150 or more of moderate-to-vigorous exercise per week
* Has a medical condition that precludes safe pursuit of gardening, i.e., severe orthopedic conditions, pending hip/knee replacement (within 6 mo.), paralysis, dementia, blindness, untreated stage 3 hypertension, or myocardial infarction, congestive heart failure, or conditions that required oxygen or hospitalization within 6 mo.
* unsuitable residence for gardening, i.e., no running water, inadequate sunshine.
* not able to speak or read English
D: Inclusion Criteria:

* Aged 6-24
* Own and use either an iPhone or Android smartphone
* Access to US Apple App Store or US GooglePlayStore

Exclusion Criteria:

* N/A

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: OPERAM: OPtimising thERapy to Prevent Avoidable Hospital Admissions in the Multimorbid Older People: a Cluster Randomised Controlled Trial
Brief Summary: The objective of this Randomised Controlled Trial (RCT) is to evaluate whether the Systematic Tool to Reduce Inappropriate Prescribing (STRIP) including STRIP assistant (STRIPA) implemented by an appropriately qualified team will lead to an improvement in clinical and economic outcomes among patients aged 70 years and more with multimorbidity and polypharmacy.


Options:
A: Inclusion Criteria:

* People 70 years of age or older
* Multimorbidity: 3 or more coexistent chronic conditions defined by 3 distinct International Classification of Diseases (ICD-10) codes with an estimated duration of 6 months or more or based on a clinical decision
* Polypharmacy i.e. five or more different regular drugs (defined as authorised medications with registration numbers) for more than 30 days.
* In inpatient: Estimated minimal length of stay within the cluster is sufficient to apply the intervention
* If outpatient: prescribing physician has GP function and has a planned appointment to conduct intervention

Exclusion Criteria:

* Inability to provide informed consent or to obtain informed consent from a proxy for patients with cognitive impairment
* Direct admission to palliative care (\< 24h after admission)
* Has passed or will pass a systematic structured drug review during this hospitalisation or within the last two months
B: Inclusion Criteria:

* age 18 years or older,
* diagnosis of T2DM and
* hospital discharge to the community.

Exclusion Criteria:

* cognitive disorders that would interfere with patient's participation,
* diagnosis of a terminal illness with a life expectancy \<1 month,
* discharge to a long-term care facility or
* inability to be followed-up.
C: Inclusion Criteria:

* more than 3 drugs over at least 3 months prior to recruitment
* german or french language (written and spoken)
* medicines use in self management

Exclusion Criteria:

* provision of Polymedication Check in the past
* living in a nursing home
* use of prefilled pill organiser or individually blistered medication
D: Inclusion Criteria:

* type 2 diabetes
* stated concern about diabetes and diabetes treatment
* poor glycemic control
* over 21 years of age

Exclusion Criteria:

* blind, deaf, otherwise unable to use the telephone or visual resources
* pregnant
* currently enrolled in other REACH Detroit research study
* in hospice care
* current radiation or chemotherapy

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Addressing Heightened Levels of Aggression in Traumatized Offenders With Psychotherapeutic Means: A Randomized Controlled Trial in Eastern DR Congo
Brief Summary: Heightened levels of aggression are fuelling violent incidents at all levels, especially in post-war regions. Narrative Exposure Therapy for Forensic Offender Rehabilitation (FORNET) aims to address trauma symptoms along with reactive and instrumental/appetitive aggression to encounter the downward cycle of perpetration and enforce a sustainable (re-)integration into civil life. In the present study, the investigators provide an adapted version of FORNET to former combatants in the North Kivu, Eastern DR Congo. Structured baseline, 3 and 6 month follow up interviews will be administered to assess the main outcome measures recent violent acts and appetitive aggression.


Options:
A: Inclusion Criteria:

* Patient at the participating primary care centers
* age 60 and older
* GHQ scores 4 or above
* Hindi MMSE scores 24 or higher
* no episodes of major depression or anxiety disorder within the past 12 months
* no current antidepressant pharmacotherapy

Exclusion Criteria:

* episode of major depression or anxiety disorder within the past 12 months
* current antidepressant pharmacotherapy
* younger than age 60
* Hindi MMSE scores less than 24
* GHQ scores less than 4
B: Eligibility criteria

* Former participant of an armed group in DR Congo
* Involvement in violent attacks

Inclusion Criteria:

* PTSD diagnosis or AAS sum score of 22 or higher

Exclusion Criteria:

* Acute intoxification (alcohol or other drugs)
* Acute psychotic symptoms
* Sign of cerebro-organic diseases
C: Inclusion Criteria:

1. Obesity (BMI \> 40 kg/m2)
2. Age: 18-65

Exclusion Criteria:

1. Diagnosis of obesity secondary to primary endocrine or systemic disease (e.g. Cushing's syndrome)
2. Evidence of clinically relevant thyroid disease
3. Chronic systematic inflammatory disease (e.g. rheumatoid arthritis)
4. Pregnancy
5. Treatment with anti-inflammatory drugs (e.g. corticosteroids)
6. Type 1 diabetes mellitus
D: Inclusion Criteria:

* 18 years or older
* Self-identified as LGBT+
* Lived in the study locale (city/region) for at least 6 months
* Plan to remain in the study locale (city/region) for at least 3 months

Exclusion Criteria:

* Located outside of Greater Toronto and Hamilton Area (Canada), Mumbai/Thane (India) or Bangkok metropolitan area (Thailand)

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Addressing Heightened Levels of Aggression in Traumatized Offenders With Psychotherapeutic Means: A Randomized Controlled Trial in Eastern DR Congo
Brief Summary: Heightened levels of aggression are fuelling violent incidents at all levels, especially in post-war regions. Narrative Exposure Therapy for Forensic Offender Rehabilitation (FORNET) aims to address trauma symptoms along with reactive and instrumental/appetitive aggression to encounter the downward cycle of perpetration and enforce a sustainable (re-)integration into civil life. In the present study, the investigators provide an adapted version of FORNET to former combatants in the North Kivu, Eastern DR Congo. Structured baseline, 3 and 6 month follow up interviews will be administered to assess the main outcome measures recent violent acts and appetitive aggression.


Options:
A: Inclusion Criteria:

* Refugee or asylum seeker from Afghanistan, speaking Dari
* reporting at least one traumatic event on a trauma list
* reporting difficulties in emotion regulation
* between the age of 15 and 21 years

Exclusion Criteria:

* Psychosis
* Serious suicidal ideations
* Currently receiving psychotherapy elsewhere
* Serious dissociation
B: Eligibility criteria

* Former participant of an armed group in DR Congo
* Involvement in violent attacks

Inclusion Criteria:

* PTSD diagnosis or AAS sum score of 22 or higher

Exclusion Criteria:

* Acute intoxification (alcohol or other drugs)
* Acute psychotic symptoms
* Sign of cerebro-organic diseases
C: Inclusion Criteria:

* Of Burmese origin
* Currently living in one of 20 target communities in Tak province, Thailand
* Primary caregiver to at least one child aged 8 to 12 years
* Child aged 8 to 12 years
* Participating in the family intervention

Exclusion Criteria:

* Children living in orphanages, boarding houses, factories or other institutions
* Persons with severe cognitive or physical disability who are impaired and unable to understand and give informed consent
D: Inclusion Criteria:

* Youth found to exhibit significant trauma symptomatology as evidenced by a score of 38 or above on the previously validated PTSD-RI symptom scale (Murray, et al. 2011) (trauma severity is the main study outcome) will be invited to join the trial. Youth must live in Lusaka, Zambia.

Exclusion Criteria:

* Youth currently receiving psychiatric care
* Youth who are actively suicidal
* Persons who are not mentally competent to give assent or whose legal guardians are not mentally competent to give consent to participate in the intervention

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Effects of Aspartame on Appetite, Body Composition and Oral Glucose Tolerance
Brief Summary: Assess the impact of chronic use of aspartame on glycemia, appetite and body composition.


Options:
A: Inclusion Criteria:

* Body mass index 18.5-29.9 kg∙m-2
* Age 18-65 years
* Able and willing to provide informed consent and safely comply with study procedures
* Females to maintain record of regular menstrual cycle phase/contraceptive use
* No anticipated changes in physical activity during the first 4 weeks of the study (e.g. holidays or training programmes)

Exclusion Criteria:

* Any reported condition or behaviour deemed either to pose undue personal risk to the participant or introduce bias
* Any diagnosed metabolic disease (e.g. type 1 or type 2 diabetes)
* Any reported use of substances which may pose undue personal risk to the participants or introduce bias into the experiment
* Lifestyle not conforming to standard sleep-wake cycle (e.g. shift worker)
* Any reported recent (\<6 months) change in body mass (± 3%)
* Use of antibiotic medication in the last 3 months
* Use of prebiotic or probiotic products in the last month
B: Inclusion Criteria:

* Age between 20-50 years;
* BMI between 28-36 kg/m2;
* Weight stabile 3 months prior to the study inclusion;
* Less than 10 hours of weekly exercise

Exclusion Criteria:

* Diabetes
* Allergic to phenylalanine or milk
* Smoking
* Pregnancy or breast-feeding
C: Inclusion Criteria:

* BMI 18-25
* Fasting blood sugar between 72 and 108 mg/dl via capillary finger-stick.

Exclusion Criteria:

-
D: Men and women, age 25 and older who were generally healthy except for higher than optimal or mildly elevated blood pressure.

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Code Blue Outcomes & Process Improvement Through Leadership Optimization Using Teleintensivists-Simulation
Brief Summary: This multicenter randomized trial will employ in-situ cardiac arrest simulations ("mock codes") to test whether using telemedicine technology to add an intensive care physician as the "copilot" for cardiac arrest resuscitation teams influences chest compression quality, resuscitation protocol adherence, team function, and provider experience.


Options:
A: Inclusion Criteria:

* 18 year old adult
* member of Mayo care team in the Midwest

Exclusion Criteria:

-Unable to provide consent
B: Inclusion:

* Emergency physicians
* Academic appointment of Instructor or Assistant Professor
* Work greater than 80% of their time in a residency and fellowship program approved by the Accreditation Council of Graduate Medical Education (ACGME), the American Osteopathic Association (AOA), or the Royal College of Physicians and Surgeons of Canada (RCPSC) will be invited to participate in the study.

Exclusion:

* Mayo Clinic emergency physicians are not eligible for this study.
C: Inclusion criteria (on-site cardiac arrest team):

* Are 18 years of age or older

Inclusion criteria (teleintensivist cardiac arrest team copilot):

* Are 18 years of age or older
* Are a board-certified or board-eligible critical care physician
* Provide clinical care through the Intermountain Healthcare Telecritical Care program

Exclusion criteria (both groups):

* Are under 18 years of age
* Are a member of the study research team
D: Inclusion Criteria: Postgraduate trainees in PGY 3 or higher -

Exclusion Criteria: Program director does not allow participation

-

Answer: C