Please select the eligibility criteria that correspond to the clinical trial below.
Title: Physical Fitness Training in Subacute Stroke (PHYS-Stroke)
Brief Summary: The aim of this study is to investigate whether a 4-week physical fitness training (target intervention) in stroke patients (subacute stage) increase the walking speed and activities of daily living compared with a control intervention (relaxation exercises). The target or control intervention is performed in addition to standard rehabilitation treatment.


Options:
A: Inclusion Criteria:

* ischemic or hemorrhagic stroke
* within 1 month of discharge from hospital
* able to stand up from a chair with or without gait aid and walk at least 5 metres
* able to understand 2-step commands

Exclusion Criteria:

* Have other neurological problems besides stroke or medically unstable.
B: Inclusion Criteria:

* Within 3 years of stroke onset
* Living in the community, operationally defined as living in one's own home, or the home of a friend, relative, or caregiver
* Walking speed 0.6-1.1 m/s determined during 10-meter walk test
* Walk without the assistance of another person
* Medically stable and approved for participation by study physician
* Intact global cognition indicated by score \> 23 on Montreal Cognitive Assessment
* Living in the community prior to stroke

Exclusion Criteria:

* Pre-existing neurological disorders (e.g., Parkinson's disease, Multiple Sclerosis, dementia, traumatic brain injury)
* Previous stroke with residual motor deficit
* Uncontrolled hypertension
* Inability to follow 3-step command
* Primary uncontrolled hearing impairment
* Severe uncontrolled visual impairment
* Any speech-language impairment affecting ability to respond verbally to auditory stimuli
* Timed Up and Go test \> 15 seconds
* Lower extremity amputation
* Any orthopedic problem affecting gait
* Concurrent participation in another clinical trial
C: Inclusion Criteria:

* Post stroke survivors of single unilateral stroke
* discharged from rehabilitation
* the ability to walk independently, with or without using an aid or orthosis
* sufficient cognitive ability,
* the ability to comprehend instruction

Exclusion Criteria:

* history of serious cardiac disease (e.g. myocardial infarction, unstable angina)
* uncontrolled blood pressure
* significant neurological or musculoskeletal conditions in addition to stroke
D: Inclusion Criteria for patients:

* diagnosis of stroke within 5-45 days after stroke
* age \>= 18 years
* able to sit for at least 30 seconds
* Barthel index \< =65 at inclusion
* considered able to perform aerobic exercise as determined by responsible physician
* Written informed consent of the patient

Exclusion Criteria:

* Patient considered unable to comply with study requirements
* stroke due to intracranial hemorrhage primarily due to bleeding from ruptured aneurysm or arteriovenous malformation
* patients with progressive stroke
* unable to perfom the required exercises due to

  1. medical problems
  2. musculo-skeletal problems
  3. neurological problems
* required help to at least 1 persons to walk before stroke due to neurological or non-neurological co-morbidities
* life expectancy of less than 1 year as determined by responsible physician
* alcohol or drug addiction within the last 6 months
* significant current psychiatric illness as defined as medication-refractory of bipolar affective disorder, psychosis, schizophrenia or suicidality
* current participation in another intervention study

Answer: D