Please select the eligibility criteria that correspond to the clinical trial below.
Title: Special Turku Atherosclerosis Risk Factor Intervention Project for Children (STRIP)
Brief Summary: 1062 children at the age of 7 months and their families were randomized 1:1 in an intervention arm and a control arm. The intervention families has received child-oriented and individualized nutritional and life-style counseling that aims at decreasing child's exposure to the known environmental atherosclerosis risk factors. The controls children receive information as given at the well-baby clinics and in school health care of children and adolescents. The hypothesis is that the intervention children have healthier food habits and serum serum lipid and lipoprotein concentrations than the controls, fewer of them start smoking, and their physical activity level is higher than that of the controls.


Options:
A: Inclusion Criteria:

* patients admitted to our institution with a diagnosis of AMI (ST segment elevation\> 0.1mV)
* older than 30 years
* with more than 8 teeth in the mouth
* with advanced periodontal disease

Exclusion Criteria:

* acute or chronical infection
* impossibility of attending the following interviews and/or the periodontal treatment
* refusing to signing the consent form
* individuals with substance abuse
* anticonvulsants and immunosuppressant drugs users
* pregnant and \\ or lactating women.
B: Inclusion Criteria:

* Subjects will be female, postmenopausal and not receiving estrogen replacement therapy.
* Subjects will be 45-70 years old at the time of telephone screening.
* Subjects will have osteopenia (T-score of -1.0 to -2.5) of the lumbar spine or femoral neck as determined by dual-energy absorptiometry (DEXA) scans.
* Subjects will have a history of generalized moderate-advanced periodontitis and will be undergoing periodontal maintenance.
* Subjects will be in good general health and willing to sign the IRB-approved consent form.

Exclusion Criteria:

* Subjects will not have an allergy or hypersensitivity to tetracyclines.
* Subjects will not have diseases or take medications that affect the inflammatory or immune responses (e.g., chronic use of non-steroidal anti-inflammatory drugs) or bone remodeling (e.g., drugs such as prescription estrogens, bisphosphonates, calcitonin or steroids).
* Subjects will not have any medical condition requiring antibiotic premedication (e.g., prosthetic heart valves, prosthetic joints, and mitral valve prolapse with regurgitation) for routine dental therapy.
* Subjects cannot have diabetes mellitus.
* Subjects cannot have had active periodontal therapy (quadrant scaling and root planing or periodontal surgery) within the past year.
* Subjects cannot have osteoporosis (T-score greater than -2.5) of the lumbar spine or femoral neck.
C: Inclusion Criteria:

* children at the age of 7 months and their families, recruited from the general population

Exclusion Criteria:

* severe sickness
D: Inclusion Criteria:

* Subjects must be 25 years of age or older
* Three or more periodontal pockets with a probing depth (PD) \> 5mm
* Have at least 20 natural teeth
* Provide informed consent and willingness to cooperate with the study protocol

Exclusion Criteria:

* History of antibiotic use in the previous three months
* Pregnant or lactating females
* Treatment with antihypertensive, antilipemic, antiarrhythmic, and other cardiovascular drugs
* Systemic diseases such as diabetes, HIV/AIDS, liver disease, chronic renal failure, tuberculosis, and autoimmune diseases
* Previous history of cardiovascular disease: Acute myocardial infarct, stable angina, unstable angina, heart failure, atrial fibrillation, atrioventricular block, peripheral vascular disease, cerebrovascular accident
* Patients who received periodontal treatment within the last 3 months
* Patients who require antibiotic prophylaxis before examination or treatment
* Patients with mental retardation and dementia

Answer: C