TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multimodal Prehabilitation to Enhance Functional Recovery After Colorectal Surgery: a Randomized Controlled Trial
Brief Summary: Despite advances in surgical care, the incidence of postoperative complications and prolonged recovery following colorectal surgery remains high. Efforts to improve the recovery process have primarily focused on the intraoperative (eg, minimally invasive surgery, afferent neural blockade) and post-operative periods (eg, "fast track" early nutrition and mobilization. The pre-operative period may in fact be a better time to intervene in the factors that contribute to recovery. The process of enhancing functional capacity of the individual in anticipation of an upcoming stressor has been termed "prehabilitation". Based on the notion that preoperative exercise would have an impact on recovery of functional capacity after colorectal surgery, our group recently conducted a randomized controlled trial. Subgroup analysis identified that patients whose functional exercise capacity improved preoperatively, regardless of exercise technique, recovered well in the postoperative period. However, one-third of patients deteriorated preoperatively despite the exercise regimen, and these patients were also at greater risk for prolonged recovery after surgery. These results suggested that exercise alone is not sufficient to attenuate the stress response in all patients. In the present trial, the impact of a multimodal prehabilitation intervention composed of exercise, nutritional supplement and psychological well-being begun in the preoperative period will be compared to one begun in the postoperative period.


Options:
A: Arm Label: Pre-surgery physiotherapy; Type: OTHER; Interventions: Other: Pre-surgery physiotherapy | Arm Label: Waiting-list; Type: OTHER; Interventions: Other: Waiting-list | Intervention Type: OTHER; Name: Pre-surgery physiotherapy; Assigned to Arm(s): Pre-surgery physiotherapy | Intervention Type: OTHER; Name: Waiting-list; Assigned to Arm(s): Waiting-list
B: Intervention Type: BEHAVIORAL; Name: Prehabilitation; Assigned to Arm(s): N/A
C: Arm Label: multimodal prehabilitation begun preop; Type: EXPERIMENTAL; Interventions: Behavioral: multimodal prehabilitation | Arm Label: Multimodal prehabilitation begun postop; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: multimodal prehabilitation | Intervention Type: BEHAVIORAL; Name: multimodal prehabilitation; Assigned to Arm(s): multimodal prehabilitation begun preop | Intervention Type: BEHAVIORAL; Name: multimodal prehabilitation; Assigned to Arm(s): Multimodal prehabilitation begun postop
D: Arm Label: Pre and postoperative exercise; Type: EXPERIMENTAL; Interventions: Other: Physical activity | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Physical activity; Assigned to Arm(s): Pre and postoperative exercise

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: TAKE-IT: Teen Adherence in Kidney Transplant Effectiveness of Intervention Trial
Brief Summary: The broad aim of the proposed study is to improve medication adherence in adolescent kidney transplant recipients. The investigators hypothesize that a multi-component intervention will improve medication adherence in the adolescent kidney transplant population. The specific aims are to determine, in a randomized clinical trial, the efficacy of a structured, multi-component intervention in improving adherence to anti-rejection medications and graft outcomes, and to identify characteristics of healthcare systems that are independently associated with adherence.


Options:
A: Arm Label: Multi-component Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Action-focused problem-solving, Device: Electronic pillbox monitoring, dose reminders, and feedback | Arm Label: Attention control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Action-focused problem-solving; Assigned to Arm(s): Multi-component Intervention | Intervention Type: DEVICE; Name: Electronic pillbox monitoring, dose reminders, and feedback; Assigned to Arm(s): Multi-component Intervention
B: Arm Label: SMASK; Type: EXPERIMENTAL; Interventions: Behavioral: SMASK | Arm Label: EnhancedSC; Type: OTHER; Interventions: Behavioral: EnhancedSC | Intervention Type: BEHAVIORAL; Name: SMASK; Assigned to Arm(s): SMASK | Intervention Type: BEHAVIORAL; Name: EnhancedSC; Assigned to Arm(s): EnhancedSC
C: Arm Label: Standard Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: mHealth; Type: EXPERIMENTAL; Interventions: Behavioral: mHealth | Intervention Type: BEHAVIORAL; Name: mHealth; Assigned to Arm(s): mHealth
D: Arm Label: Advagraf; Type: EXPERIMENTAL; Interventions: Drug: Advagraf | Arm Label: Prograf; Type: ACTIVE_COMPARATOR; Interventions: Drug: Prograf | Intervention Type: DRUG; Name: Advagraf; Assigned to Arm(s): Advagraf | Intervention Type: DRUG; Name: Prograf; Assigned to Arm(s): Prograf

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: TAKE-IT: Teen Adherence in Kidney Transplant Effectiveness of Intervention Trial
Brief Summary: The broad aim of the proposed study is to improve medication adherence in adolescent kidney transplant recipients. The investigators hypothesize that a multi-component intervention will improve medication adherence in the adolescent kidney transplant population. The specific aims are to determine, in a randomized clinical trial, the efficacy of a structured, multi-component intervention in improving adherence to anti-rejection medications and graft outcomes, and to identify characteristics of healthcare systems that are independently associated with adherence.


Options:
A: Arm Label: Inform Me: web-based education tool; Type: EXPERIMENTAL; Interventions: Behavioral: Inform Me: web-based education tool | Arm Label: Control Standard of Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Inform Me: web-based education tool; Assigned to Arm(s): Inform Me: web-based education tool
B: Arm Label: Multi-component Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Action-focused problem-solving, Device: Electronic pillbox monitoring, dose reminders, and feedback | Arm Label: Attention control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Action-focused problem-solving; Assigned to Arm(s): Multi-component Intervention | Intervention Type: DEVICE; Name: Electronic pillbox monitoring, dose reminders, and feedback; Assigned to Arm(s): Multi-component Intervention
C: Arm Label: Alert; Type: EXPERIMENTAL; Interventions: Other: Alert | Arm Label: Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Alert; Assigned to Arm(s): Alert
D: Arm Label: Telehome Monitoring; Type: EXPERIMENTAL; Interventions: Device: Telehome Monitoring | Arm Label: Standard of Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: Telehome Monitoring; Assigned to Arm(s): Telehome Monitoring

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: TAKE-IT: Teen Adherence in Kidney Transplant Effectiveness of Intervention Trial
Brief Summary: The broad aim of the proposed study is to improve medication adherence in adolescent kidney transplant recipients. The investigators hypothesize that a multi-component intervention will improve medication adherence in the adolescent kidney transplant population. The specific aims are to determine, in a randomized clinical trial, the efficacy of a structured, multi-component intervention in improving adherence to anti-rejection medications and graft outcomes, and to identify characteristics of healthcare systems that are independently associated with adherence.


Options:
A: Arm Label: HED-Start Intervention arm; Type: EXPERIMENTAL; Interventions: Behavioral: HED-Start | Arm Label: Standard care arm; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: HED-Start; Assigned to Arm(s): HED-Start Intervention arm
B: Arm Label: Multi-component Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Action-focused problem-solving, Device: Electronic pillbox monitoring, dose reminders, and feedback | Arm Label: Attention control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Action-focused problem-solving; Assigned to Arm(s): Multi-component Intervention | Intervention Type: DEVICE; Name: Electronic pillbox monitoring, dose reminders, and feedback; Assigned to Arm(s): Multi-component Intervention
C: Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Behavioral Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Behavioral Interventions for Dialysis Facilities | Intervention Type: BEHAVIORAL; Name: Behavioral Interventions for Dialysis Facilities; Assigned to Arm(s): Behavioral Intervention
D: Arm Label: Standard of Care (Control); Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Patient-Guided; Type: EXPERIMENTAL; Interventions: Other: Patient-Guided | Arm Label: Educator-Guided; Type: EXPERIMENTAL; Interventions: Other: Patient-Guided, Other: Educator-Guided | Intervention Type: OTHER; Name: Patient-Guided; Assigned to Arm(s): Educator-Guided, Patient-Guided | Intervention Type: OTHER; Name: Educator-Guided; Assigned to Arm(s): Educator-Guided

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multicenter, Open Label Extension Study of 8 mg PEG-uricase in Subjects Who Completed Protocols C0405 or C0406 for Symptomatic Gout
Brief Summary: This is an open-label extension phase of two double-blind, placebo-controled Phase 3 protocols evaluating PEG-uricase in the treatment of hyperuricemic subjects with symptomatic gout. The purpose of this study is to provide a continuation of treatment to subjects completing the double-blind studies and obtain long-term safety and efficacy data.


Options:
A: Arm Label: q2 RCT; Type: EXPERIMENTAL; Interventions: Biological: pegloticase | Arm Label: q4 RCT; Type: EXPERIMENTAL; Interventions: Biological: pegloticase | Arm Label: Placebo in RCT; Type: EXPERIMENTAL; Interventions: Biological: pegloticase | Intervention Type: BIOLOGICAL; Name: pegloticase; Assigned to Arm(s): Placebo in RCT, q2 RCT, q4 RCT
B: Arm Label: Febuxostat 40 mg QD; Type: EXPERIMENTAL; Interventions: Drug: Febuxostat | Arm Label: Febuxostat 80 mg QD; Type: EXPERIMENTAL; Interventions: Drug: Febuxostat | Arm Label: Allopurinol 200 mg or 300 mg QD; Type: ACTIVE_COMPARATOR; Interventions: Drug: Allopurinol | Intervention Type: DRUG; Name: Febuxostat; Assigned to Arm(s): Febuxostat 40 mg QD | Intervention Type: DRUG; Name: Febuxostat; Assigned to Arm(s): Febuxostat 80 mg QD | Intervention Type: DRUG; Name: Allopurinol; Assigned to Arm(s): Allopurinol 200 mg or 300 mg QD
C: Arm Label: q2 wks; Type: EXPERIMENTAL; Interventions: Biological: pegloticase | Arm Label: q4 wks; Type: EXPERIMENTAL; Interventions: Biological: pegloticase | Arm Label: placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: placebo | Intervention Type: OTHER; Name: placebo; Assigned to Arm(s): placebo | Intervention Type: BIOLOGICAL; Name: pegloticase; Assigned to Arm(s): q2 wks, q4 wks
D: Intervention Type: DRUG; Name: Oxypurinol; Assigned to Arm(s): N/A

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Low Molecular Weight Heparin (Enoxaparin Sodium) and Standard Unfractionated Heparin for Hemodialysis Anticoagulation
Brief Summary: Low-molecular weight heparins (LMWHs) as well as Unfractionated heparin (UFH) is used as anticoagulation during hemodialysis (HD) therapy. In this study the investigators have compared clinical efficacy and safety of LMWH and UFH, and their effect on lipid profile.


Options:
A: Arm Label: A; Type: EXPERIMENTAL; Interventions: Drug: law molecular weigth heparin | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Drug: unfractioned heparin | Intervention Type: DRUG; Name: law molecular weigth heparin; Assigned to Arm(s): A | Intervention Type: DRUG; Name: unfractioned heparin; Assigned to Arm(s): B
B: Arm Label: Tinzaparin; Type: EXPERIMENTAL; Interventions: Drug: Tinzaparin, Drug: Placebo (for Unfractionated Heparin) | Arm Label: Unfractionated Heparin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Unfractionated Heparin, Drug: Placebo (for Tinzaparin) | Intervention Type: DRUG; Name: Tinzaparin; Assigned to Arm(s): Tinzaparin | Intervention Type: DRUG; Name: Unfractionated Heparin; Assigned to Arm(s): Unfractionated Heparin | Intervention Type: DRUG; Name: Placebo (for Tinzaparin); Assigned to Arm(s): Unfractionated Heparin | Intervention Type: DRUG; Name: Placebo (for Unfractionated Heparin); Assigned to Arm(s): Tinzaparin
C: Arm Label: enoxaparin; Type: EXPERIMENTAL; Interventions: Drug: low molecular weight heparin (enoxaparin sodium) | Arm Label: standard unfractionated heparin; Type: ACTIVE_COMPARATOR; Interventions: Drug: standard unfractionated heparin | Intervention Type: DRUG; Name: low molecular weight heparin (enoxaparin sodium); Assigned to Arm(s): enoxaparin | Intervention Type: DRUG; Name: standard unfractionated heparin; Assigned to Arm(s): standard unfractionated heparin
D: Arm Label: Apixaban 2.5 mg twice daily and standard of care; Type: ACTIVE_COMPARATOR; Interventions: Drug: Apixaban 2.5 milligram Oral Tablet | Arm Label: Standard of care and no anticoagulation; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: Apixaban 2.5 milligram Oral Tablet; Assigned to Arm(s): Apixaban 2.5 mg twice daily and standard of care

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Use of Transcranial Direct Current Stimulation in the Recovery of Postural Control in Stroke
Brief Summary: This study investigates if transcranial Direct Current Stimulation (tDCS) is effective in the recovery of postural control in stroke rehabilitation.


Options:
A: Arm Label: High Intensity; Type: EXPERIMENTAL; Interventions: Behavioral: Bilateral movements and neuromuscular electrical stimulation | Arm Label: Low Intensity; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Bilateral movements and neuromuscular electrical stimulation | Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Bilateral movements and sham electrical stimulation | Intervention Type: BEHAVIORAL; Name: Bilateral movements and neuromuscular electrical stimulation; Assigned to Arm(s): High Intensity | Intervention Type: BEHAVIORAL; Name: Bilateral movements and neuromuscular electrical stimulation; Assigned to Arm(s): Low Intensity | Intervention Type: BEHAVIORAL; Name: Bilateral movements and sham electrical stimulation; Assigned to Arm(s): Control
B: Arm Label: Standard Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Implicit Learning Approach; Type: EXPERIMENTAL; Interventions: Other: Implicit Learning Approach | Intervention Type: OTHER; Name: Implicit Learning Approach; Assigned to Arm(s): Implicit Learning Approach
C: Arm Label: SHAM TDCS; Type: SHAM_COMPARATOR; Interventions: Device: Application of Transcranial direct current stimulation (TDCS) | Arm Label: True TDCS; Type: ACTIVE_COMPARATOR; Interventions: Device: Transcranial Direct current stimulation | Intervention Type: DEVICE; Name: Application of Transcranial direct current stimulation (TDCS); Assigned to Arm(s): SHAM TDCS | Intervention Type: DEVICE; Name: Transcranial Direct current stimulation; Assigned to Arm(s): True TDCS
D: Arm Label: Prism adaptation + anodal tDCS; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Prism Adaptation, Device: Anodal tDCS | Arm Label: Prism Adaptation + Sham tDCS; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Prism Adaptation, Device: Sham tDCS | Arm Label: Prism adaptation + no tDCS; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Prism Adaptation | Intervention Type: BEHAVIORAL; Name: Prism Adaptation; Assigned to Arm(s): Prism Adaptation + Sham tDCS, Prism adaptation + anodal tDCS, Prism adaptation + no tDCS | Intervention Type: DEVICE; Name: Anodal tDCS; Assigned to Arm(s): Prism adaptation + anodal tDCS | Intervention Type: DEVICE; Name: Sham tDCS; Assigned to Arm(s): Prism Adaptation + Sham tDCS

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Use of Transcranial Direct Current Stimulation in the Recovery of Postural Control in Stroke
Brief Summary: This study investigates if transcranial Direct Current Stimulation (tDCS) is effective in the recovery of postural control in stroke rehabilitation.


Options:
A: Arm Label: Mirror therapy with tDCS; Type: EXPERIMENTAL; Interventions: Behavioral: Mirror Therapy with tDCS | Arm Label: Mirror Therapy; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Mirror Therapy | Arm Label: Control Intervention; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Control Intervention | Arm Label: Mirror Therapy with sham-tDCS; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Mirror Therapy with sham-tDCS | Intervention Type: BEHAVIORAL; Name: Mirror Therapy with tDCS; Assigned to Arm(s): Mirror therapy with tDCS | Intervention Type: BEHAVIORAL; Name: Mirror Therapy with sham-tDCS; Assigned to Arm(s): Mirror Therapy with sham-tDCS | Intervention Type: BEHAVIORAL; Name: Mirror Therapy; Assigned to Arm(s): Mirror Therapy | Intervention Type: BEHAVIORAL; Name: Control Intervention; Assigned to Arm(s): Control Intervention
B: Arm Label: real-tDCS with MI-BCI; Type: ACTIVE_COMPARATOR; Interventions: Device: real-tDCS with MI-BCI | Arm Label: sham-tDCS with MI-BCI; Type: SHAM_COMPARATOR; Interventions: Device: real-tDCS with MI-BCI | Intervention Type: DEVICE; Name: real-tDCS with MI-BCI; Assigned to Arm(s): real-tDCS with MI-BCI, sham-tDCS with MI-BCI
C: Arm Label: SHAM TDCS; Type: SHAM_COMPARATOR; Interventions: Device: Application of Transcranial direct current stimulation (TDCS) | Arm Label: True TDCS; Type: ACTIVE_COMPARATOR; Interventions: Device: Transcranial Direct current stimulation | Intervention Type: DEVICE; Name: Application of Transcranial direct current stimulation (TDCS); Assigned to Arm(s): SHAM TDCS | Intervention Type: DEVICE; Name: Transcranial Direct current stimulation; Assigned to Arm(s): True TDCS
D: Arm Label: hemiplegic patient; Type: EXPERIMENTAL; Interventions: Device: transcranial Direct current stimulation | Arm Label: patient control; Type: SHAM_COMPARATOR; Interventions: Device: transcranial Direct current stimulation | Intervention Type: DEVICE; Name: transcranial Direct current stimulation; Assigned to Arm(s): hemiplegic patient, patient control

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Evaluation of Diagnostic Value of 3-T MRI in Suspected Prostate Cancer
Brief Summary: The purpose of the study is to evaluate the usefulness of 3-T magnetic resonance imaging (MRI) in the evaluation of suspected prostate cancer. Men with suspected prostate cancer based on serum prostate-specific antigen antigen (PSA) value are included. Men are randomized to pre-biopsy MRI or no MRI groups in ratio 1:1. Standard transrectal ultrasound guided biopsies will be taken in addition to extra biopsies from lesions suspicious based on MRI evaluation. Hypothesis is that more prostate cancers will be found after MRI evaluation.


Options:
A: Arm Label: Prostate biopsy; Type: OTHER; Interventions: Procedure: Prostate biopsy | Intervention Type: PROCEDURE; Name: Prostate biopsy; Assigned to Arm(s): Prostate biopsy
B: Arm Label: MRI done; Type: EXPERIMENTAL; Interventions: Device: magnetic resonance imaging, Siemens | Arm Label: no MRI; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: magnetic resonance imaging, Siemens; Assigned to Arm(s): MRI done
C: Arm Label: MRI-arm; Type: EXPERIMENTAL; Interventions: Device: MRI, Procedure: MRI-targeted biopsy | Arm Label: TRUS-biopsy arm; Type: ACTIVE_COMPARATOR; Interventions: Procedure: TRUS-biopsy | Intervention Type: DEVICE; Name: MRI; Assigned to Arm(s): MRI-arm | Intervention Type: PROCEDURE; Name: MRI-targeted biopsy; Assigned to Arm(s): MRI-arm | Intervention Type: PROCEDURE; Name: TRUS-biopsy; Assigned to Arm(s): TRUS-biopsy arm
D: Intervention Type: OTHER; Name: biologic sample preservation procedure; Assigned to Arm(s): N/A | Intervention Type: OTHER; Name: laboratory biomarker analysis; Assigned to Arm(s): N/A | Intervention Type: OTHER; Name: study of socioeconomic and demographic variables; Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: diffusion-weighted magnetic resonance imaging; Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: dynamic contrast-enhanced magnetic resonance imaging; Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: multiparametric magnetic resonance imaging; Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: quality-of-life assessment; Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: transperineal prostate biopsy; Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: transrectal prostate biopsy; Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: ultrasound-guided prostate biopsy; Assigned to Arm(s): N/A

Answer: B