Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Placebo-Controlled, Dose-Ranging Study of Quadrivalent HPV Virus-Like Particle (VLP) Vaccine in 16- to 23-Year-Old Women
Brief Summary: This study was conducted in 2 parts. Part A was a randomized, double-blind, placebo-controlled, multicenter, sequential dose-escalating evaluation. Part B was a randomized, double-blind (operating under in-house blinding procedures), placebo-controlled, multicenter, dose-ranging study.


Options:
A: Arm Label: Quadrivalent Human Papillomavirus (HPV) Vaccine; Type: EXPERIMENTAL; Interventions: Biological: Gardasil, human papillomavirus (type 6, 11, 16, 18) recombinant vaccine | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Biological: Matching Placebo | Intervention Type: BIOLOGICAL; Name: Gardasil, human papillomavirus (type 6, 11, 16, 18) recombinant vaccine; Assigned to Arm(s): Quadrivalent Human Papillomavirus (HPV) Vaccine | Intervention Type: BIOLOGICAL; Name: Matching Placebo; Assigned to Arm(s): Placebo
B: Arm Label: Quadrivalent HPV (Types 6,11,16,18) L1 VLP Vaccine; Type: EXPERIMENTAL; Interventions: Biological: Quadrivalent HPV (Types 6,11,16,18) L1 VLP Vaccine 20/40/40/20 | Arm Label: Quadrivalent HPV (Types 6,11,16,18) L1 VLP Vaccine 40/40/40/40; Type: EXPERIMENTAL; Interventions: Biological: Quadrivalent HPV (Types 6,11,16,18) L1 VLP Vaccine 40/40/40/40 | Arm Label: Quadrivalent HPV (Types 6,11,16,18) L1 VLP Vaccine 80/80/40/80; Type: EXPERIMENTAL; Interventions: Biological: Quadrivalent HPV (Types 6,11,16,18) L1 VLP Vaccine 80/80/40/80 | Arm Label: Placebo (mcg) (Aluminum Adjuvant) 225; Type: EXPERIMENTAL; Interventions: Biological: Placebo (mcg) (Aluminum Adjuvant)225 | Arm Label: Placebo (mcg) (Aluminum Adjuvant) 450; Type: EXPERIMENTAL; Interventions: Biological: Placebo (mcg) (Aluminum Adjuvant) 450 | Intervention Type: BIOLOGICAL; Name: Quadrivalent HPV (Types 6,11,16,18) L1 VLP Vaccine 20/40/40/20; Assigned to Arm(s): Quadrivalent HPV (Types 6,11,16,18) L1 VLP Vaccine | Intervention Type: BIOLOGICAL; Name: Quadrivalent HPV (Types 6,11,16,18) L1 VLP Vaccine 40/40/40/40; Assigned to Arm(s): Quadrivalent HPV (Types 6,11,16,18) L1 VLP Vaccine 40/40/40/40 | Intervention Type: BIOLOGICAL; Name: Quadrivalent HPV (Types 6,11,16,18) L1 VLP Vaccine 80/80/40/80; Assigned to Arm(s): Quadrivalent HPV (Types 6,11,16,18) L1 VLP Vaccine 80/80/40/80 | Intervention Type: BIOLOGICAL; Name: Placebo (mcg) (Aluminum Adjuvant)225; Assigned to Arm(s): Placebo (mcg) (Aluminum Adjuvant) 225 | Intervention Type: BIOLOGICAL; Name: Placebo (mcg) (Aluminum Adjuvant) 450; Assigned to Arm(s): Placebo (mcg) (Aluminum Adjuvant) 450
C: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Biological: Comparator: HPV 16 L1 Vaccine | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Biological: Comparator: Placebo | Intervention Type: BIOLOGICAL; Name: Comparator: HPV 16 L1 Vaccine; Assigned to Arm(s): 1 | Intervention Type: BIOLOGICAL; Name: Comparator: Placebo; Assigned to Arm(s): 2
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Biological: V501 | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Biological: Comparator: Placebo | Arm Label: 3; Type: EXPERIMENTAL; Interventions: Biological: Human Papillomavirus (HPV) 16 Monovalent | Intervention Type: BIOLOGICAL; Name: V501; Assigned to Arm(s): 1 | Intervention Type: BIOLOGICAL; Name: Comparator: Placebo; Assigned to Arm(s): 2 | Intervention Type: BIOLOGICAL; Name: Human Papillomavirus (HPV) 16 Monovalent; Assigned to Arm(s): 3

Answer: B