Please select the eligibility criteria that correspond to the clinical trial below.
Title: Mindfulness Based Relapse Prevention: Efficacy and Mechanisms
Brief Summary: The broad, long-term objective of the proposed randomized clinical trial is to evaluate the efficacy, moderators and mechanisms of change of two cognitive-behavioral aftercare treatments for alcohol and other drug (AOD) use disorders in preventing AOD relapse compared to treatment as usual (TAU) offered in the community. The two cognitive-behavioral aftercare treatments are relapse prevention (RP) and Mindfulness-Based Relapse Prevention (MBRP), which integrates mindfulness meditation and RP aftercare components.


Options:
A: Inclusion Criteria:

* completion or scheduled completion (i.e., within 2 weeks) of Inpatient or Intensive Outpatient treatment
* fluency in English
* enrollment in a substance abuse aftercare program
* medical clearance by referring provider
* willingness to accept random assignment to treatment condition

Exclusion Criteria:

* already participated in the pilot MBRP trial conducted by this research team
* participation in the comorbid disorders or relapse prevention groups offered at partner agency
* comorbid psychosis (including schizophrenia, schizoaffective or other schizophreniform disorder)and/or dementia, acute suicidality/intent to harm others, severe cognitive impairment, and high risk of withdrawal or medical complications stemming from relapse which would require a higher level of care.
B: Inclusion Criteria:

* Age 18-60+
* Current chronic pain condition
* Current use of prescription opioid agonist or mixed agonist-antagonist analgesics for \>90 days

Exclusion Criteria:

* Prior experience with Mindfulness-Based Stress Reduction, Mindfulness-Based Cognitive Therapy, or Mindfulness-Based Relapse Prevention
* Active suicidality, schizophrenia, psychotic disorder, and/or severe substance dependence (other than opioid dependence)
* Opioid misuse as determined by Current Opioid Misuse Measure
C: Inclusion Criteria:

* Latino migrants
* Must speak English or Spanish
* 18-70 years of age
* Screen positive to at least one substance use and one mental health problem

Exclusion Criteria:

* Current or recent (last 3 months) substance use treatment (more than 1 visit with a provider at a behavioral health clinic)
* Planning to receive behavioral health services (i.e., have an appointment scheduled in the next 2 months)
* Evidence that the patient lacks capacity to consent to the study
* Evidence of current suicidal risk or harm to others (affirmative responses to questions 4 and/or 5 on Paykel suicide questionnaire)- patient can be rescreened in 30 days
D: Inclusion Criteria:

1. Age: 18 to 29 years
2. Tobacco use of at least 10 cigarettes per day for at least 6 months
3. Alcohol use of 5 or more binges/month (Binge = 5 or more drinks for males, 4 or more for females)

Exclusion Criteria:

1. Baseline (orientation meeting) CO level \< 10
2. Self report of pre-existing bipolar disorder, schizophrenia, other delusional disorder
3. Self report of pre-existing diagnosis of personality disorder (e.g. borderline, antisocial, schizoaffective personality disorders)
4. Self report of alcohol use of 4 drinks or more on 6 or more nights per week.

Answer: A