Please select the eligibility criteria that correspond to the clinical trial below.
Title: Impact and Safety of a Physical Training Program on Health-related Quality of Life in Patients With Cirrhosis and Portal Hypertension
Brief Summary: Physical training improves quality of life (QOL) in non-hepatic diseases. It is possible that the same effect happens in patients with cirrhosis and portal hypertension. Hepatic encephalopathy may also benefit from physical activity by increasing ammonia metabolism. The intention of this study is to assess if patients can improve their QOL and hepatic encephalopathy during a physical training program, and to address its safety.


Options:
A: Inclusion Criteria:

* Diagnosis of chronic kidney disease and receiving dialysis treatment
* Previous experience of at least 2 or more muscle cramps per month in at least 3 of the last 6 months
* Men or women aged 18 years and older
* Capacity to provide informed consent

Exclusion Criteria:

* Patients less than 18 years of age
* Women who are pregnant and the human fetus
* Serious, uncontrolled disease (including serious psychological disorders) likely to interfere with the study and/or likely to cause death within the study duration
* Participation in another clinical during the last 12 weeks
* Known allergic reactions against any component of the study drug or its comparator(s)
* Known contraindication to any component of the study drug or its comparator(s)
* Concurrent diseases which exclude the administration of therapy as outlined by the study protocol
* Subjects who, in the opinion of the investigator, are not likely to complete the study for whatever reason.
B: Inclusion Criteria:

* Biopsy-proven or clinically evident cirrhosis
* Able to perform exercise

Exclusion Criteria:

* Overt hepatic encephalopathy grades 3 or 4
* Cardiovascular complications (pulmonary hypertension, heart failure)
* Diabetes mellitus and microangiopathic complications, or under treatment with insulin
* Renal failure
* Portal hypertension with high risk for variceal bleeding
* Hepatocellular carcinoma
C: Inclusion Criteria:

* For patients to be included in our study, they had to experience regular episodes of NLC and are in good mental health.
* The participants had to agree to the study protocol and complete the program.
* After eligibility was verified, written informed consent was obtained.

Exclusion Criteria:

* Older adults taking quinine or sleep medication and those with orthopedic problems or with severe medical problems and co morbidity, which can cause muscular spasms and/or cramps.
D: Inclusion Criteria:

* Age \>18 years.
* Diagnosis of post thrombotic syndrome.
* Median life expectancy of greater than 2 years.
* Previous history of lower extremity deep venous thrombosis.

Exclusion Criteria:

* Acute venous thrombosis of the lower extremity within the last 180 days.
* Unable to participate in lymphedema therapy due to monetary, physical or transportation limitations.
* Uncontrolled illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements.
* Pregnant women and women in their first post-partum month.

Answer: B