Please select the eligibility criteria that correspond to the clinical trial below.
Title: Randomized Clinical Trial in Juvenile Fibromyalgia
Brief Summary: Juvenile fibromyalgia is a chronic pain condition that can cause considerable suffering and difficulty in an adolescent's day-to-day activities. The purpose of this study is to determine whether coping skills training, when combined with usual medical care, can reduce pain and disability in adolescents with fibromyalgia.

Study hypotheses: 1) Adolescents who receive coping skills training combined with their usual medical care will show significantly greater reductions in functional disability, pain, and depressive symptoms at the end of the acute treatment phase than adolescents who receive fibromyalgia education with their usual medical care. 2) Adolescents who receive coping skills training with their usual medical care will show significantly lower levels of functional disability, pain, and depressive symptoms at the end of a six-month maintenance phase than adolescents who receive fibromyalgia education with their usual medical care.


Options:
A: Inclusion Criteria:

* Diagnosis of JPFS based upon widespread pain for over 3 months, at least 5 tender points, and associated features such as sleep difficulty, fatigue, and abdominal discomfort
* Average pain intensity greater than 4 on the Visual Analog Scale
* Functional disability score greater than 7
* Stable medications for 8 weeks prior to study entry

Exclusion Criteria:

* Other chronic rheumatic diseases, such as juvenile rheumatoid arthritis or lupus
* Significant developmental delay or impairments, such as autism, cerebral palsy, or mental retardation
* Present or lifetime psychiatric diagnosis that meets DSM-IV criteria for panic disorder, bipolar disorder, major depressive disorder, or psychosis
* Opioid medications are disallowed when used on an ongoing basis for treatment of fibromyalgia pain
B: Inclusion Criteria:

* Youth between the ages of 12 and 18 with type 1 diabetes characterized by an HbA1c value great than 9%
* Caregivers willing to participate
* Family members reading English at 5th grade level
* Willing to be randomized.

Exclusion Criteria:

* Youth with intellectual disability
* Parent or youth who doesn't speak English
C: Inclusion Criteria:

* Patients between 10-25 years with diagnosed IBD
* Informed consent or assent by patients and (if necessary) parents

Exclusion Criteria:

* IBD patients with parental report of mental retardation
* IBD patients receiving psychopharmacological treatment (antidepressants or benzodiazepines) for depression or anxiety
* No mastery of the Dutch language
* IBD patients with diagnosed: Bipolar disorder, Schizophrenia/psychotic disorder, Autism spectrum disorders, Obsessive-compulsive disorder, Posttraumatic stress disorder/Acute stress disorder, or Substance use disorder
* Physician reported substance abuse (alcohol, drugs) in the past month
* Clinician reported Selective mutism
* IBD patients already participating in an (psychological of psychopharmacological) intervention study
* IBD patients who received 8 sessions of manualized cognitive behavioral therapy last year
* current psychological treatment
D: Inclusion Criteria:

* Step One

  1. Ages 11 to 17 inclusive.
  2. Capable of completing CDI
  3. English-speaking.
  4. Meeting diagnostic criteria for IBD (The date of diagnosis = date of the first diagnostic test confirming IBD)
  5. Absence of mental retardation by history
  6. Having at least one appointment at the gastroenterology clinic at CHP.
* Step Two: Assessment

  1) CDI and/or CDI-P equal to or more than 9 at Step 1
* At Intervention Phase

  1. CDI score equal to or more than 9 AND/OR CDI-P score equal to or more than 9 at T0.
  2. Absence of recent suicide attempt (within one month of study enrollment) or depression severity requiring acute psychiatric hospitalization),
  3. Age 11-17 years inclusive,
  4. Presence of at least one biological parent.

Exclusion Criteria:

1. Current major depression or dysthymia by Diagnostic and Statistical Manual (DSM)-IV criteria
2. History or current episode of bipolar disorder, eating disorder, or psychotic disorder by DSM-IV criteria.
3. Mental retardation by history
4. Antidepressant or stimulant medications within one month of assessment
5. Suicidality with plan or of severity requiring immediate psychiatric hospitalization or significant act involving intentional self-harm, e.g. cutting or overdose, resulting in medical attention.
6. Unacceptable risk for dangerousness to others as indicated by homicidal (or other violent) ideation, intent or plan or action, or use of illegal weapons.
7. Current pregnancy by history.
8. Substance abuse within one month of enrollment other than nicotine dependence.
9. Current treatment with cognitive behavioral therapy (CBT) or failure of previous CBT trial for depression judged adequate by at least 12 treatment sessions over a period of less than 1 year conducted by an appropriately trained mental health provider.

Answer: A