TrialPanorama/Dataset huggingface dataset:
Please select the outcome measures that correspond to the clinical trial below.
Title: Effect of a Weight Management Program for Overweight and Obese Children: a Randomized Controlled Trial
Brief Summary: The purpose of this study, and its original contribution to research, is to determine the impact of a physical activity skill development and parent centered family weight management program on the weight, cardiovascular health, physical activity, dietary intake and sedentary behaviors of overweight and obese children.


Options:
A: BMI z score (24 months (end of intervention)); BMI z score (60 months of age (followup at 5 years of age)); BMI z score (Follow-up at 11 years of age)
B: To evaluate and compare in overweight children the effectiveness of the following interventions: a parent-centered dietary modification program; a physical activity skill development program; and a parent-centered dietary modification + physical activity skill development program.
C: Mother BMI (Baseline, 6 months, 12 months); Infant Weight (Baseline, 6 months, 12 months)
D: Effectiveness of a nutrition advice programme in exclusive breastfeeding. (1 year); Effectiveness of a nutrition advice programme in dietary intake (1 year); Effectiveness of a nutrition advice programme in dietary intake (4 years); Effectiveness of a nutrition advice programme in dietary intake (8 years); Effectiveness of a nutrition advice programme in dietary intake (12 years)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Effect of a Weight Management Program for Overweight and Obese Children: a Randomized Controlled Trial
Brief Summary: The purpose of this study, and its original contribution to research, is to determine the impact of a physical activity skill development and parent centered family weight management program on the weight, cardiovascular health, physical activity, dietary intake and sedentary behaviors of overweight and obese children.


Options:
A: Change from baseline in energy dense food consumption at 12 months (12 months); Change from baseline in nutrient dense food consumption at 12 months (12 months)
B: To evaluate and compare in overweight children the effectiveness of the following interventions: a parent-centered dietary modification program; a physical activity skill development program; and a parent-centered dietary modification + physical activity skill development program.
C: Primary Outcome Measure: BMI (6 months, 1 year, 2 year, 5 year)
D: body mass index (three years)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Effect of a Weight Management Program for Overweight and Obese Children: a Randomized Controlled Trial
Brief Summary: The purpose of this study, and its original contribution to research, is to determine the impact of a physical activity skill development and parent centered family weight management program on the weight, cardiovascular health, physical activity, dietary intake and sedentary behaviors of overweight and obese children.


Options:
A: Change in Child Physical Activity (Approximately 10-13 months. Baseline will be collected over a 2-month period, followed by a 9 month intervention. Then follow-up assessment will be collected over a 2 month period.); Change in Child Dietary Intake (Approximately 10-13 months. Baseline will be collected over a 2-month period, followed by a 9 month intervention. Then follow-up assessment will be collected over a 2 month period.)
B: Exhibited emotion, Feeding decisions, self-reported attitudes, beliefs and intentions; perceptual responses (At lab visit)
C: Change in Children´s Consumption of Foods From Baseline to 3 Months by Intervention Assignment (0, 3 months); Change in Children´s Time of Physical Activity From Baseline to 3 Months by Intervention Assignment (0, 3 months); Change in Score z of Body Mass Index From Baseline to 3 Months by Intervention Assignment (0, 3 month)
D: To evaluate and compare in overweight children the effectiveness of the following interventions: a parent-centered dietary modification program; a physical activity skill development program; and a parent-centered dietary modification + physical activity skill development program.

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Effect of a Weight Management Program for Overweight and Obese Children: a Randomized Controlled Trial
Brief Summary: The purpose of this study, and its original contribution to research, is to determine the impact of a physical activity skill development and parent centered family weight management program on the weight, cardiovascular health, physical activity, dietary intake and sedentary behaviors of overweight and obese children.


Options:
A: Percent of children overweight or obese (BMI ≥ 85th%) at 2 years of life (2 years)
B: Change in child's fruit and vegetable intake as measured by short dietary screener (Baseline to 4 months, 12 month follow-up, 16-month follow-up, 24-month follow-up, and 28-month follow-up); Change in child's fruit and vegetable intake as measured by 24-hour dietary recall (Baseline to 4 months, 16-month follow-up, and 28-month follow-up); Change in child's intake of sugar-sweetened beverages and processed snacks as measured by short dietary questionnaire (Baseline to 4 months, 12-month follow-up, 16-month follow-up, 24-month follow-up, and 28-month follow-up); Change in child's intake of sugar-sweetened beverages and processed snacks as measured by 24-hour dietary recall (Baseline to 4 months, 16-month follow-up, and 28-month follow-up); Change in child's caloric intake as a percent of estimated energy requirements (Baseline to 4 months, 16-month follow-up, and 28-month follow-up); Change in child's dermal carotenoid levels (Baseline to 4 months, 16-month follow-up, and 28-month follow-up); Change in child's diet quality (Baseline to 4 months, 16-month follow-up, and 28-month follow-up)
C: Absolute change in mean accelerometry counts over 6 days (baseline, end of intervention, six months after end of intervention)
D: To evaluate and compare in overweight children the effectiveness of the following interventions: a parent-centered dietary modification program; a physical activity skill development program; and a parent-centered dietary modification + physical activity skill development program.

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Effect of a Weight Management Program for Overweight and Obese Children: a Randomized Controlled Trial
Brief Summary: The purpose of this study, and its original contribution to research, is to determine the impact of a physical activity skill development and parent centered family weight management program on the weight, cardiovascular health, physical activity, dietary intake and sedentary behaviors of overweight and obese children.


Options:
A: Total Body Bone Mineral Density (TBBMD) (Baseline, 1 year, and 2 years)
B: To evaluate and compare in overweight children the effectiveness of the following interventions: a parent-centered dietary modification program; a physical activity skill development program; and a parent-centered dietary modification + physical activity skill development program.
C: Daily physical activity > 60 minutes (4 years)
D: Cardiovascular disease risk factors (obesity, blood pressure, blood lipid & lipoprotein) (6 Months)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Effect of a Weight Management Program for Overweight and Obese Children: a Randomized Controlled Trial
Brief Summary: The purpose of this study, and its original contribution to research, is to determine the impact of a physical activity skill development and parent centered family weight management program on the weight, cardiovascular health, physical activity, dietary intake and sedentary behaviors of overweight and obese children.


Options:
A: Change in glycemic control, change in dietary intake (18 months)
B: Fruit and Vegetable Consumption, servings per week (3 weeks); Perceived Behavioral Control scale score (3 weeks); Attitudes scale score (3 weeks); Intrinsic Motivation scale score (3 weeks); Fruit and vegetable consumption, servings per week (5 weeks); Perceived Behavioral Control scale score (5 weeks); Attitudes scale score (5 weeks); Intrinsic Motivation scale score (5 weeks)
C: To evaluate and compare in overweight children the effectiveness of the following interventions: a parent-centered dietary modification program; a physical activity skill development program; and a parent-centered dietary modification + physical activity skill development program.
D: Growth trajectories (using BMI, waist circumference), body composition (3 months)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Effect of a Weight Management Program for Overweight and Obese Children: a Randomized Controlled Trial
Brief Summary: The purpose of this study, and its original contribution to research, is to determine the impact of a physical activity skill development and parent centered family weight management program on the weight, cardiovascular health, physical activity, dietary intake and sedentary behaviors of overweight and obese children.


Options:
A: To evaluate and compare in overweight children the effectiveness of the following interventions: a parent-centered dietary modification program; a physical activity skill development program; and a parent-centered dietary modification + physical activity skill development program.
B: BMI and aerobic fitness (1 schoolyear)
C: Change in Prevalence of Overweight and Obesity Using Body Mass Index Percentile for Age and Sex (Baseline, 24 months); Change in Waist Circumference (Baseline, 78 months); Prevalence of Acanthosis Nigricans (Baseline, 24 months); Change in Prevalence of Overweight and Obesity Using Body Mass Index Percentile for Age and Sex (Baseline, 78 months); Change in Waist Circumference (Baseline, 24 months); Prevalence of Acanthosis Nigricans (Baseline, 78 months)
D: Change in Weight Status (baseline and 2 year follow-up)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Effect of a Weight Management Program for Overweight and Obese Children: a Randomized Controlled Trial
Brief Summary: The purpose of this study, and its original contribution to research, is to determine the impact of a physical activity skill development and parent centered family weight management program on the weight, cardiovascular health, physical activity, dietary intake and sedentary behaviors of overweight and obese children.


Options:
A: Child BMI
B: Child BMI Z-score (Pre-intervention); Child BMI Z-score (post-intervention); Child BMI Z-score (6-months post-intervention); Child BMI Z-score (12-months post-intervention)
C: To evaluate and compare in overweight children the effectiveness of the following interventions: a parent-centered dietary modification program; a physical activity skill development program; and a parent-centered dietary modification + physical activity skill development program.
D: Absolute change in mean accelerometry counts over 6 days (baseline, end of intervention, six months after end of intervention)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: A Multicenter, Randomized, Double-blind, Placebo-controlled, Dose-ranging, Parallel Group Phase II Study to Evaluate the Safety, Efficacy and Pharmacokinetics of the Oral Neurokinin-1 Receptor Antagonist, GW679769, When Administered With Intravenous Ondansetron Hydrochloride for the Prevention of Post-operative Nausea and Vomiting (PONV) and Post-discharge Nausea and Vomiting (PDNV) in Female Subjects With Known Risk Factors for PONV Who Are Undergoing Surgical Procedures Associated With an Increased Emetogenic Risk
Brief Summary: This study is looking at a range of doses of this NK-1 receptor antagonist drug, for both safety and effectiveness in prevention PONV


Options:
A: Prevention of PONV in the 24 hours following end of surgery; Tolerability (24 hours)
B: Number of subjects who achieve a complete response (defined as no vomiting, no retching, no rescue therapy, and no premature discontinuation from the study) during the first 24 hour evaluation period following emergence from anesthesia
C: incidence and severity of postoperative nausea and vomiting (upto 2 days after surgery)
D: severity of nasea (immediated postop to 48hrs after surgery)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Vasoconstrictors as Alternatives to Albumin After Large Volume Paracentesis in Cirrhosis
Brief Summary: This clinical trial compares a combination of two drugs that constrict blood vessels (Octreotide LAR and Midodrine) to albumin after large volume paracentesis. Subjects have cirrhosis and ascites.


Options:
A: Time to Recurrence of Ascites. (Variable depending on the patient, average 10 days)
B: To evaluate complications (renal failure, hepatic encephalopathy, hyponatremia, infection and gastrointestinal bleeding) in patients with cirrhosis awaiting for liver transplant. (When 97 patients are included (% of the whole population))
C: Number of patients with control of ascites (3 months)
D: Paracentesis free survival (6 months)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Efficacy of Tailored Cognitive-Behavioral Therapy for Chronic Back Pain
Brief Summary: This clinical trial compares two psychological treatments for back pain.


Options:
A: Multiple standardized measures of key domains of the chronic pain experience (12 weeks)
B: Back pain-related dysfunction (26 weeks); Bothersomeness of back pain (26 weeks)
C: Pain (Baseline and change after 15 weeks, 6 months, 1 year, 2 years follow up. The outcome measures is going to report a change over time.)
D: SF-36, Roland Morris Disability Questionnaire, Quebec back pain disability (before intervention)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Integrated CBT for Substance Use and Depressive Disorders
Brief Summary: The purpose of this study is to determine whether Integrated Cognitive Behavioral Therapy or Twelve Step Facilitation Therapy is most effective for treatment of dually diagnosed veterans with depressive and substance use disorders.


Options:
A: N/A
B: Expired Carbon Monoxide (Baseline and treatment phases, 2-mont and 6-month follow up.)
C: Increase in parental competence at nine intervals over 39 month study period (birth-3 year postpartum)
D: Alcohol consumption (12 weeks); Time to lapse (12 weeks); amount of alcohol consumption (12 weeks)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Linezolid vs Vancomycin/Cefazolin in the Treatment of Hemodialysis Patients With Catheter-Related Gram-Positive Bloodstream Infections
Brief Summary: This study will treat hemodialysis patients who have a central catheter that is thought to be infected with a specific bacteria (Gram positive bacteria).


Options:
A: The number of major catheter-related infections (CRI) defined as either catheter-related clinical sepsis without bloodstream infection or catheter-related bloodstream infection (CRBSI), during the ICU stay (after renal replacement therapy session)
B: Success Rate (90 days)
C: Number of Participants With Microbiological Response at Test-of-Cure (TOC) Visit (Short term follow-up (STFU) visit for TOC (2 to 3 weeks after the last dose of study medication))
D: The catheters dysfunction rate (as partial or complete occlusion or infection associated with dialysis catheter)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Safety and Efficacy of Low Carbohydrate Diet in Obesity and Type 2 DM: RCT
Brief Summary: This study is designed to address the hypothesis that in obese patients with type 2 diabetes mellitus (DM), a low carbohydrate diet not specifically restricted in calories compared to low fat, caloric restricted diet over 24 months will cause 5% greater reduction in body weight in patients with obesity and type 2 DM, be safe, and will not have any detrimental effects on serum lipid concentrations.


Options:
A: Percent Change in Body Weight From Baseline to 48 Weeks (Baseline, 48 weeks)
B: weight loss
C: Changes in adipose tissue (Baseline and 3 months and 6 months)
D: N/A

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Efficacy of Antidepressants in Chronic Back Pain
Brief Summary: The purpose of this study is to determine whether gabapentin is efficacious as an analgesic for chronic low back pain.


Options:
A: Transformed Descriptor Differential Scale-Pain Intensity Scores Adjusted for Time (Baseline to Week 12 with Interim Measurement at Weeks 1, 2, 3, 4, 5, 7 and 9)
B: Area of pin-prick hyperalgesia (Change from baseline visit to day 14 of treatment sessions); Area of touch-evoked allodynia (Change from baseline visit to day 14 of treatment sessions)
C: Mean Change in Baseline Observation Carried Forward (BOCF) Average Daily Pain Score (10 weeks)
D: The primary study objective is to assess the relative efficacy of G-ER versus placebo in reducing the average daily pain score from the baseline week to the final week of the efficacy treatment period (Treatment Week 10) in patients with PHN; Daily pain scores will be measured using an electronic diary.

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Divalproex Sodium in the Treatment of PTSD: A Placebo-Controlled Study
Brief Summary: The purposes of this study are:

* To study the efficacy of divalproex in the treatment of PTSD;
* To study the plasma GABA (gamma aminobutyric acid) levels before and after treatment with divalproex in PTSD.


Options:
A: Clinician Administered Posttraumatic Stress Disorder Scale (12 week)
B: Clinician Administered PTSD Scale (CAPS) (8weeks)
C: PTSD Symptoms (Post-treatment, ten weeks); Depression Symptoms (Measured at Post-Treatment, at 10 weeks); State Anxiety (Measured at Post-Treatment, at 10 weeks)
D: Clinician-Administered PTSD Scale (CAPS) for DSM-IV (Session of Week 0); Clinician-Administered PTSD Scale (CAPS) for DSM-IV (Session of Week 7); Clinician-Administered PTSD Scale (CAPS) for DSM-IV (Session of Week 26)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: A 12 Month Double-blind, Randomized, Parallel-group, Placebo-controlled, Multi-center Trial to Investigate the Efficacy and Safety of Vagifem Low Dose (10 mcg 17beta-estradiol Vaginal Tablet) for the Treatment of Postmenopausal Atrophic Vaginitis Symptoms
Brief Summary: This trial is conducted in North America. The purpose of this study is to determine if Vagifem Low Dose is an effective and safe treatment for patients suffering from postmenopausal atrophic vaginitis.


Options:
A: Co-Primary Efficacy Endpoint: Frequency of Moderate to Severe Vasomotor Symptoms (MITT-VMS) (Baseline and Week 4); Co-Primary Efficacy Endpoint: Frequency of Moderate to Severe Vasomotor Symptoms (MITT-VMS) (Baseline and Week 12); Co-Primary Efficacy Endpoint: Severity of Moderate to Severe Vasomotor Symptoms (MITT-VMS) (Baseline and Week 4); Co-Primary Efficacy Endpoint: Severity of Moderate to Severe Vasomotor Symptoms (MITT-VMS) (Baseline and Week 12); Primary Safety Endpoint: Endometrial Protection - Hyperplasia (Baseline and Month 12)
B: To evaluate the effects of Bazedoxifene/Conjugate Estrogens (CE) combinations on the incidence of endometrial hyperplasia in postmenopausal women. (one year)
C: Clinical symptoms (after 12 months)
D: Relief of vaginal symptoms (following 12 weeks of treatment.)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: A Strategy Study of Immediate Versus Deferred Initiation of Antiretroviral Therapy for AIDS Disease-Free Survival in HIV-Infected Persons Treated for Tuberculosis With CD4 Less Than 250 Cells/mm^3
Brief Summary: The purpose of this study is to determine the best time to begin anti-HIV treatment in individuals who have HIV and tuberculosis (TB).

Study hypothesis: Immediate antiretroviral therapy (ART), initiated after approximately 2 weeks of TB treatment, will reduce the frequency of other AIDS-defining illnesses and death in HIV-infected participants being treated for TB by at least 40% at week 48 when compared to deferred ART, initiated at after 8-12 weeks of TB treatment.


Options:
A: Mortality (2 years)
B: Survival (At 36 months)
C: Retention in care with undetectable viral load (12 months after HIV testing)
D: Percent of Participants Who Survived Without AIDS Progression. (Through week 48)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Exercise Dose and Insulin Sensitivity in Obese Children
Brief Summary: The study is a behavioral clinical trial of aerobic exercise to determine dose-response effects on risk for type 2 diabetes, fatness, fitness, blood cholesterol levels, and other cardiovascular risk factors in overweight elementary schoolchildren.

The hypothesis is that the more exercise a child does, the more benefit he or she will gain in reducing the risk of diabetes and other cardiovascular diseases.

An ancillary study examined effects on cognition and achievement.


Options:
A: body mass index trajectory (change) (baseline, 1, 2 and 3 years)
B: Body mass index (One school year)
C: Insulin area under the curve (oral glucose tolerance test) (10-15 weeks); Body composition (% body fat, visceral fat) (10-15 weeks); Aerobic fitness (10-15 weeks); Cognition (Executive function) (10-15 weeks)
D: Our outcome measure was reduction of screen time (4 waves of data)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Exercise Dose and Insulin Sensitivity in Obese Children
Brief Summary: The study is a behavioral clinical trial of aerobic exercise to determine dose-response effects on risk for type 2 diabetes, fatness, fitness, blood cholesterol levels, and other cardiovascular risk factors in overweight elementary schoolchildren.

The hypothesis is that the more exercise a child does, the more benefit he or she will gain in reducing the risk of diabetes and other cardiovascular diseases.

An ancillary study examined effects on cognition and achievement.


Options:
A: BMI will be assessed during lifestyle intervention in (1) children and adolescents and (2) adults vs. placebo (21 months)
B: Body fat percentage (One year (interim analysis))
C: Our outcome measure was reduction of screen time (4 waves of data)
D: Insulin area under the curve (oral glucose tolerance test) (10-15 weeks); Body composition (% body fat, visceral fat) (10-15 weeks); Aerobic fitness (10-15 weeks); Cognition (Executive function) (10-15 weeks)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Improving Diabetes Through Primary Care Translation (IMPACT)
Brief Summary: The goal of our research program is to successfully translate empirical knowledge regarding diabetes treatment and management into sustainable clinical practice. The study hypothesis is that implementation of a multicomponent intervention will result in meaningful improvement in clinical performance measures at the clinic that include average A1c (Hemoglobin A1c), average systolic blood pressure, and national clinical performance measures at a reasonable cost to the health system.


Options:
A: Death or non-fatal myocardial infarction (Up to 10 months)
B: N/A
C: Change from baseline in blood glucose level (Baseline and 12 months); Change from baseline in blood pressure (Baseline and 12 months); Change from baseline in body mass index (Baseline and 12 months)
D: Percentage of Subjects Who Reach Optimal Long-acting Insulin Dose (12 weeks)

Answer: B