Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Catheter Ablation vs Anti-arrhythmic Drug Therapy for Atrial Fibrillation Trial
Brief Summary: The (Catheter Ablation Versus Anti-arrhythmic Drug Therapy for Atrial Fibrillation Trial) CABANA Trial has the overall goal of establishing the appropriate roles for medical and ablative intervention for atrial fibrillation (AF). The CABANA Trial is designed to test the hypothesis that the treatment strategy of left atrial catheter ablation for the purpose of eliminating atrial fibrillation (AF) will be superior to current state-of-the-art therapy with either rate control or rhythm control drugs for decreasing the incidence of the composite endpoint of total mortality, disabling stroke, serious bleeding, or cardiac arrest in patients with untreated or incompletely treated AF.


Options:
A: Arm Label: Drug Treatment; Type: ACTIVE_COMPARATOR; Interventions: Device: Radiofrequency ablation, antiarrhythmic drugs, Drug: Amiodarone, flecainide, propafenone, quinidine, dofetilide, sotalol, cibenzoline, beta blocking and calcium channel blocking agents and antiarrhythmic drugs | Arm Label: ThermoCool Radiofrequency Catheter; Type: ACTIVE_COMPARATOR; Interventions: Device: Radiofrequency ablation, antiarrhythmic drugs, Device: ThermoCool Radiofrequency Catheter | Intervention Type: DEVICE; Name: Radiofrequency ablation, antiarrhythmic drugs; Assigned to Arm(s): Drug Treatment, ThermoCool Radiofrequency Catheter | Intervention Type: DRUG; Name: Amiodarone, flecainide, propafenone, quinidine, dofetilide, sotalol, cibenzoline, beta blocking and calcium channel blocking agents and antiarrhythmic drugs; Assigned to Arm(s): Drug Treatment | Intervention Type: DEVICE; Name: ThermoCool Radiofrequency Catheter; Assigned to Arm(s): ThermoCool Radiofrequency Catheter
B: Arm Label: Left Atrial Ablation; Type: ACTIVE_COMPARATOR; Interventions: Device: Left atrial ablation | Arm Label: Rate or Rhythm Control Therapy; Type: ACTIVE_COMPARATOR; Interventions: Drug: Rate or Rhythm Control Therapy | Intervention Type: DEVICE; Name: Left atrial ablation; Assigned to Arm(s): Left Atrial Ablation | Intervention Type: DRUG; Name: Rate or Rhythm Control Therapy; Assigned to Arm(s): Rate or Rhythm Control Therapy
C: Arm Label: No Amiodarone; Type: ACTIVE_COMPARATOR; Interventions: Other: No Amiodarone | Arm Label: Amiodarone; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: No Amiodarone; Assigned to Arm(s): No Amiodarone
D: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Ranolazine placebo, Drug: Dronedarone placebo | Arm Label: Ranolazine 750 mg; Type: EXPERIMENTAL; Interventions: Drug: Ranolazine, Drug: Dronedarone placebo | Arm Label: Dronedarone 225 mg; Type: EXPERIMENTAL; Interventions: Drug: Dronedarone, Drug: Ranolazine placebo | Arm Label: Ranolazine 750 mg + Dronedarone 225 mg; Type: EXPERIMENTAL; Interventions: Drug: Ranolazine, Drug: Dronedarone | Arm Label: Ranolazine 750 mg + Dronedarone 150 mg; Type: EXPERIMENTAL; Interventions: Drug: Ranolazine, Drug: Dronedarone | Intervention Type: DRUG; Name: Ranolazine; Assigned to Arm(s): Ranolazine 750 mg, Ranolazine 750 mg + Dronedarone 150 mg, Ranolazine 750 mg + Dronedarone 225 mg | Intervention Type: DRUG; Name: Dronedarone; Assigned to Arm(s): Dronedarone 225 mg, Ranolazine 750 mg + Dronedarone 150 mg, Ranolazine 750 mg + Dronedarone 225 mg | Intervention Type: DRUG; Name: Ranolazine placebo; Assigned to Arm(s): Dronedarone 225 mg, Placebo | Intervention Type: DRUG; Name: Dronedarone placebo; Assigned to Arm(s): Placebo, Ranolazine 750 mg

Answer: B