TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Multisite Randomized Trial of Battle Viro: A Mobile Gaming App to Improve ART Adherence for Youth
Brief Summary: Despite the need for consistent adherence to medical care, youth living with HIV have low rates of adherence to medications and treatment. There are few interventions to improve adherence to HIV medications and treatment for youth, and there is a great need for novel approaches that are engaging for this age group. The investigators developed an intervention that includes a mobile gaming app that is integrated with a 7-day electronic medication device and text messages. During gameplay, youth fight HIV in colorful organ systems. A small previous project found that the intervention helped youth who were newly starting medications for HIV by improving adherence and decreasing HIV virus in their bodies (viral load). This proposed project will test the intervention with larger number of youth (100) who are newly starting HIV treatment and medications in New England, Georgia, and in Mississippi. The investigators want to determine if adherence is improved and viral load is reduced in this larger sample.


Options:
A: Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Mobile phone reminder | Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Mobile phone reminder | Intervention Type: BEHAVIORAL; Name: Mobile phone reminder; Assigned to Arm(s): Control, Intervention
B: Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: miPlan intervention | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: miPlan intervention; Assigned to Arm(s): Intervention
C: Arm Label: Cell-phone assisted; Type: EXPERIMENTAL; Interventions: Device: Cell-phone | Arm Label: control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: Cell-phone; Assigned to Arm(s): Cell-phone assisted
D: Arm Label: Multilevel Gaming Adherence; Type: EXPERIMENTAL; Interventions: Behavioral: Multilevel Gaming Adherence Intervention | Arm Label: Treatment as Usual +; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Treatment as Usual + | Intervention Type: BEHAVIORAL; Name: Multilevel Gaming Adherence Intervention; Assigned to Arm(s): Multilevel Gaming Adherence | Intervention Type: BEHAVIORAL; Name: Treatment as Usual +; Assigned to Arm(s): Treatment as Usual +

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Multisite Randomized Trial of Battle Viro: A Mobile Gaming App to Improve ART Adherence for Youth
Brief Summary: Despite the need for consistent adherence to medical care, youth living with HIV have low rates of adherence to medications and treatment. There are few interventions to improve adherence to HIV medications and treatment for youth, and there is a great need for novel approaches that are engaging for this age group. The investigators developed an intervention that includes a mobile gaming app that is integrated with a 7-day electronic medication device and text messages. During gameplay, youth fight HIV in colorful organ systems. A small previous project found that the intervention helped youth who were newly starting medications for HIV by improving adherence and decreasing HIV virus in their bodies (viral load). This proposed project will test the intervention with larger number of youth (100) who are newly starting HIV treatment and medications in New England, Georgia, and in Mississippi. The investigators want to determine if adherence is improved and viral load is reduced in this larger sample.


Options:
A: Arm Label: Multilevel Gaming Adherence; Type: EXPERIMENTAL; Interventions: Behavioral: Multilevel Gaming Adherence Intervention | Arm Label: Treatment as Usual +; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Treatment as Usual + | Intervention Type: BEHAVIORAL; Name: Multilevel Gaming Adherence Intervention; Assigned to Arm(s): Multilevel Gaming Adherence | Intervention Type: BEHAVIORAL; Name: Treatment as Usual +; Assigned to Arm(s): Treatment as Usual +
B: Arm Label: Control; Type: SHAM_COMPARATOR; Interventions: Behavioral: Wise app with fitness reminders | Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Wise app with medication adherence reminders | Intervention Type: BEHAVIORAL; Name: Wise app with medication adherence reminders; Assigned to Arm(s): Intervention | Intervention Type: BEHAVIORAL; Name: Wise app with fitness reminders; Assigned to Arm(s): Control
C: Arm Label: SMS Reminder; Type: EXPERIMENTAL; Interventions: Other: SMS Reminder | Arm Label: Interactive Reminder; Type: EXPERIMENTAL; Interventions: Other: Interactive Reminder | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: SMS Reminder; Assigned to Arm(s): SMS Reminder | Intervention Type: OTHER; Name: Interactive Reminder; Assigned to Arm(s): Interactive Reminder
D: Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Other: EpxBreastfeeding, Other: Baby book survey | Arm Label: Control; Type: OTHER; Interventions: Other: Baby book survey | Intervention Type: OTHER; Name: EpxBreastfeeding; Assigned to Arm(s): Intervention | Intervention Type: OTHER; Name: Baby book survey; Assigned to Arm(s): Control, Intervention

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Multisite Randomized Trial of Battle Viro: A Mobile Gaming App to Improve ART Adherence for Youth
Brief Summary: Despite the need for consistent adherence to medical care, youth living with HIV have low rates of adherence to medications and treatment. There are few interventions to improve adherence to HIV medications and treatment for youth, and there is a great need for novel approaches that are engaging for this age group. The investigators developed an intervention that includes a mobile gaming app that is integrated with a 7-day electronic medication device and text messages. During gameplay, youth fight HIV in colorful organ systems. A small previous project found that the intervention helped youth who were newly starting medications for HIV by improving adherence and decreasing HIV virus in their bodies (viral load). This proposed project will test the intervention with larger number of youth (100) who are newly starting HIV treatment and medications in New England, Georgia, and in Mississippi. The investigators want to determine if adherence is improved and viral load is reduced in this larger sample.


Options:
A: Arm Label: Cell-phone assisted; Type: EXPERIMENTAL; Interventions: Device: Cell-phone | Arm Label: control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: Cell-phone; Assigned to Arm(s): Cell-phone assisted
B: Arm Label: Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Reminders; Type: EXPERIMENTAL; Interventions: Behavioral: Reminders | Intervention Type: BEHAVIORAL; Name: Reminders; Assigned to Arm(s): Reminders
C: Arm Label: social networking on mobile phone; Type: EXPERIMENTAL; Interventions: Other: social networking on mobile phone | Arm Label: no social networking on mobile phone; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: social networking on mobile phone; Assigned to Arm(s): social networking on mobile phone
D: Arm Label: Multilevel Gaming Adherence; Type: EXPERIMENTAL; Interventions: Behavioral: Multilevel Gaming Adherence Intervention | Arm Label: Treatment as Usual +; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Treatment as Usual + | Intervention Type: BEHAVIORAL; Name: Multilevel Gaming Adherence Intervention; Assigned to Arm(s): Multilevel Gaming Adherence | Intervention Type: BEHAVIORAL; Name: Treatment as Usual +; Assigned to Arm(s): Treatment as Usual +

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized, Multicenter, Double-blind, Parallel-group, Active-control Study of the Efficacy and Safety of Sparsentan for the Treatment of Immunoglobulin A Nephropathy
Brief Summary: To determine the long-term (approximately 2 years) nephroprotective potential of treatment with sparsentan as compared to an angiotensin receptor blocker in patients with immunoglobulin A nephropathy (IgAN).


Options:
A: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Drug: supportive therapy with: ACE-inhibitor / ARB / Statin | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Drug: supportive and immunosuppressive therapy | Intervention Type: DRUG; Name: supportive therapy with: ACE-inhibitor / ARB / Statin; Assigned to Arm(s): A | Intervention Type: DRUG; Name: supportive and immunosuppressive therapy; Assigned to Arm(s): B
B: Intervention Type: DRUG; Name: Telmisartan; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Combination of Telmisartan and Ramipril; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Ramipril; Assigned to Arm(s): N/A
C: Arm Label: sparsentan; Type: EXPERIMENTAL; Interventions: Drug: sparsentan | Arm Label: irbesartan; Type: ACTIVE_COMPARATOR; Interventions: Drug: irbesartan | Arm Label: dapagliflozin + sparsentan (Sub study); Type: EXPERIMENTAL; Interventions: Drug: sparsentan, Drug: Dapagliflozin | Arm Label: sparsentan (Sub Study); Type: EXPERIMENTAL; Interventions: Drug: sparsentan | Intervention Type: DRUG; Name: sparsentan; Assigned to Arm(s): dapagliflozin + sparsentan (Sub study), sparsentan, sparsentan (Sub Study) | Intervention Type: DRUG; Name: irbesartan; Assigned to Arm(s): irbesartan | Intervention Type: DRUG; Name: Dapagliflozin; Assigned to Arm(s): dapagliflozin + sparsentan (Sub study)
D: Arm Label: Abelmoschus manihot (AM); Type: EXPERIMENTAL; Interventions: Drug: Abelmoschus manihot | Arm Label: Losartan; Type: EXPERIMENTAL; Interventions: Drug: Losartan | Intervention Type: DRUG; Name: Losartan; Assigned to Arm(s): Losartan | Intervention Type: DRUG; Name: Abelmoschus manihot; Assigned to Arm(s): Abelmoschus manihot (AM)

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Pilot Trial of the Mini-AFTERc Intervention to Manage Fear of Cancer Recurrence in Breast Cancer Patients
Brief Summary: People treated for breast cancer often live with an ongoing fear that the cancer will recur. This fear may develop and impact on their mental health and quality of life. The Mini-AFTERc study is a pilot trial of a brief cognitive behavioural communication intervention, designed to reduce fear of cancer recurrence (FCR) in breast cancer patients. This pilot trial aims to determine the acceptability and practicality of introducing the Mini-AFTERc intervention into everyday practice, and inform the development of a full randomised controlled trial.


Options:
A: Intervention Type: BEHAVIORAL; Name: Community Interlink Program; Assigned to Arm(s): N/A
B: Arm Label: breast cancer radiation therapy; Type: N/A; Interventions: N/A
C: Arm Label: Intervention group; Type: EXPERIMENTAL; Interventions: Behavioral: Mini-AFTERc | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Mini-AFTERc; Assigned to Arm(s): Intervention group
D: Arm Label: Survivorship Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Survivorship Intervention | Arm Label: Facing Forward; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Facing Forward | Intervention Type: BEHAVIORAL; Name: Survivorship Intervention; Assigned to Arm(s): Survivorship Intervention | Intervention Type: BEHAVIORAL; Name: Facing Forward; Assigned to Arm(s): Facing Forward

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Day 3 vs Day 5 Embryo Transfer for Patients With Low Embryo Numbers Going Through in Vitro Fertilization (PILOT STUDY)
Brief Summary: The purpose of this small-scale pilot study (10 patients) is to test the study protocol for an RCT comparing IVF outcomes between day 3 and day 5 embryo transfer in patients with five or fewer embryos in a fresh embryo transfer in vitro fertilization (IVF) cycle. Information derived from this RCT would allow us to maximize the chances of success for these patients undergoing IVF.


Options:
A: Arm Label: freeze all embryos following PGD; Type: EXPERIMENTAL; Interventions: Procedure: elective cryopreservation of available embryos after PGD | Arm Label: elective fresh embryo transfer; Type: ACTIVE_COMPARATOR; Interventions: Procedure: PGD and elective fresh embryo transfer plus cryopreservation of supernumerary available embryos after PGD | Intervention Type: PROCEDURE; Name: elective cryopreservation of available embryos after PGD; Assigned to Arm(s): freeze all embryos following PGD | Intervention Type: PROCEDURE; Name: PGD and elective fresh embryo transfer plus cryopreservation of supernumerary available embryos after PGD; Assigned to Arm(s): elective fresh embryo transfer
B: Arm Label: Control arm; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Fresh embryo transfer | Arm Label: Intervention arm; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Frozen embryo transfer | Intervention Type: PROCEDURE; Name: Fresh embryo transfer; Assigned to Arm(s): Control arm | Intervention Type: PROCEDURE; Name: Frozen embryo transfer; Assigned to Arm(s): Intervention arm
C: Arm Label: day 3 embryo transfer; Type: EXPERIMENTAL; Interventions: Procedure: day 3 uterine transfer | Arm Label: day 5 embryo transfer; Type: EXPERIMENTAL; Interventions: Procedure: day 5 uterine transfer | Intervention Type: PROCEDURE; Name: day 3 uterine transfer; Assigned to Arm(s): day 3 embryo transfer | Intervention Type: PROCEDURE; Name: day 5 uterine transfer; Assigned to Arm(s): day 5 embryo transfer
D: Arm Label: Blastocyst; Type: EXPERIMENTAL; Interventions: Procedure: Embryo transfer | Arm Label: Cleavage; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Embryo transfer | Intervention Type: PROCEDURE; Name: Embryo transfer; Assigned to Arm(s): Blastocyst, Cleavage

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Red Blood Cell Transfusion Decision Based on Arterial-venous Oxygen Difference Can Reduce Mortality in Critically Ill Patients
Brief Summary: Anemia is common in intensive care unit (ICU) patients and often appears early in the ICU course. The optimal management red blood cells RBC transfusion in critically ill patients remains controversial and clinical studies in this field have usually been based on transfusion thresholds. In the "TRICC" Trial, patients assigned to a restrictive transfusion strategy (transfusion if Hb\<7 g/dL) had similar mortality to patients transfused if Hb\<10 g/dL. Notably, none of the large RCT tried to focus on a personalize RBC transfusion protocol, i.e. a transfusion protocol which address the individual need for transfusion basing on physiological approach. We therefore hypothesized that patients with high extraction of oxygen could benefit more of RBCs transfusion regardless their hemoglobin levels.


Options:
A: Arm Label: Liberal Transfusion Strategy; Type: ACTIVE_COMPARATOR; Interventions: Other: Red blood cell transfusion | Arm Label: Restrictive Transfusion Strategy; Type: ACTIVE_COMPARATOR; Interventions: Other: Red blood cell transfusion | Intervention Type: OTHER; Name: Red blood cell transfusion; Assigned to Arm(s): Liberal Transfusion Strategy | Intervention Type: OTHER; Name: Red blood cell transfusion; Assigned to Arm(s): Restrictive Transfusion Strategy
B: Arm Label: Appropriate transfusion policy; Type: N/A; Interventions: N/A | Arm Label: Non-Appropriate transfusion policy; Type: N/A; Interventions: N/A
C: Arm Label: Liberal (10 g/dL) Transfusion Strategy; Type: EXPERIMENTAL; Interventions: Biological: Liberal (10 g/dL) Transfusion Strategy | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Biological: Restrictive (Symptomatic) Transfusion Strategy | Intervention Type: BIOLOGICAL; Name: Liberal (10 g/dL) Transfusion Strategy; Assigned to Arm(s): Liberal (10 g/dL) Transfusion Strategy | Intervention Type: BIOLOGICAL; Name: Restrictive (Symptomatic) Transfusion Strategy; Assigned to Arm(s): 2
D: Arm Label: Restrictive Red blood cell Transfusion; Type: EXPERIMENTAL; Interventions: Other: Red blood cell Transfusion | Arm Label: Liberal Red blood Cell Transfusion; Type: ACTIVE_COMPARATOR; Interventions: Other: Red blood cell Transfusion | Intervention Type: OTHER; Name: Red blood cell Transfusion; Assigned to Arm(s): Liberal Red blood Cell Transfusion, Restrictive Red blood cell Transfusion

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: One Plus One Equals Two - Will That do? A Randomized Controlled Trial to Evaluate Collegial Midwifery Practice to Prevent Perineal Trauma
Brief Summary: A new clinical practice to reduce perineal trauma has been adopted by many maternity wards in Sweden. This practice involves collegial midwifery assistance during the second stage of labor and the birth of the baby. The midwife responsible for the birth is the primary carer of the woman and the second midwife observes the birth or assists the primary midwife if asked to. The hypothesis is that the presence and support of an extra midwife will reduce severe perineal trauma (trauma to the anal sphincter (OASI)).

The objective of this trial is to evaluate whether collegial midwifery assistance during the second stage reduces perineal trauma grade III-IV.


Options:
A: Arm Label: Perineal device used; Type: OTHER; Interventions: Device: Perineal protection device | Arm Label: No intervention; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: Perineal protection device; Assigned to Arm(s): Perineal device used
B: Arm Label: hands on; Type: EXPERIMENTAL; Interventions: Procedure: hands on | Arm Label: hands off; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: PROCEDURE; Name: hands on; Assigned to Arm(s): hands on
C: Arm Label: Two midwives; Type: EXPERIMENTAL; Interventions: Behavioral: Two midwives | Arm Label: One midwife; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Two midwives; Assigned to Arm(s): Two midwives
D: Arm Label: I; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Ritgens maneuver | Arm Label: II; Type: OTHER; Interventions: Procedure: Standard care (Manual support of the perineum) | Intervention Type: PROCEDURE; Name: Ritgens maneuver; Assigned to Arm(s): I | Intervention Type: PROCEDURE; Name: Standard care (Manual support of the perineum); Assigned to Arm(s): II

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Shared Decision Making and Patient Engagement Program During AECOPD Hospitalization
Brief Summary: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Patients require good communication with the physician to improve control illness. Shared decision making is a promising opportunity for chronic disease management due to the relative cost, medicine optimization and decreases hospital admissions/re-admissions


Options:
A: Arm Label: Intervention; Type: ACTIVE_COMPARATOR; Interventions: Other: Active implementation of a guideline for chronic disease | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: External control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Active implementation of a guideline for chronic disease; Assigned to Arm(s): Intervention
B: Arm Label: Experimental group; Type: EXPERIMENTAL; Interventions: Other: Shared decision making | Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Shared decision making; Assigned to Arm(s): Experimental group
C: Arm Label: Group A; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Support, management, educational, counselling, follow-up | Arm Label: Group B; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Support, management, educational, counselling, follow-up | Arm Label: Group C; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Support, management, educational, counselling, follow-up; Assigned to Arm(s): Group A, Group B
D: Arm Label: Intervention Arm; Type: EXPERIMENTAL; Interventions: Behavioral: Opinion leader educational letter | Arm Label: Control/Standard Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Opinion leader educational letter; Assigned to Arm(s): Intervention Arm

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: STroke Secondary Prevention With Catheter ABLation and EDoxaban for Patients With Non-valvular Atrial Fibrillation: STABLED Study
Brief Summary: Catheter ablation (CA) has been reported to reduce risk of stroke in patients with nonvalvular atrial fibrillation (NVAF) in retrospective studies, but risk and benefit of CA has not been well elucidated in NVAF with recent cerebral infarction in prospective randomized trials.


Options:
A: Arm Label: Cohort 1; Type: N/A; Interventions: N/A | Arm Label: Cohort 2; Type: N/A; Interventions: N/A | Arm Label: Cohort 3; Type: N/A; Interventions: N/A | Arm Label: Cohort 4; Type: N/A; Interventions: N/A | Arm Label: Cohort 5; Type: N/A; Interventions: N/A
B: Arm Label: Study Arm; Type: ACTIVE_COMPARATOR; Interventions: Drug: Coumadin | Arm Label: Control Arm; Type: ACTIVE_COMPARATOR; Interventions: Drug: Coumadin | Intervention Type: DRUG; Name: Coumadin; Assigned to Arm(s): Study Arm | Intervention Type: DRUG; Name: Coumadin; Assigned to Arm(s): Control Arm | Intervention Type: DRUG; Name: Coumadin; Assigned to Arm(s): Control Arm, Study Arm
C: Arm Label: Bridging anti-coagulation; Type: ACTIVE_COMPARATOR; Interventions: Drug: low molecular weight heparin or unfractionated heparin | Arm Label: Continued oral anti-coagulation; Type: EXPERIMENTAL; Interventions: Drug: Warfarin or coumadin | Intervention Type: DRUG; Name: low molecular weight heparin or unfractionated heparin; Assigned to Arm(s): Bridging anti-coagulation | Intervention Type: DRUG; Name: Warfarin or coumadin; Assigned to Arm(s): Continued oral anti-coagulation
D: Arm Label: Standard medical therapy group; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Catheter ablation group; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Catheter ablation | Intervention Type: PROCEDURE; Name: Catheter ablation; Assigned to Arm(s): Catheter ablation group

Answer: D