Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Adjunctive Antimicrobial Therapy of Periodontitis: Long-Term Effects on Disease Progression and Oral Microbiological Colonization
Brief Summary: The purpose of this study is to determine the size of the benefit of an adjunctive empiric antibiotic therapy compared to standard mechanical debridement and oral hygiene instructions in a representative sample of German periodontitis patients.


Options:
A: Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Procedure: Scaling and root planing (SRP), Other: Placebo 400 (14 days), Other: Placebo 500 | Arm Label: MTZ 250 (7 days); Type: ACTIVE_COMPARATOR; Interventions: Procedure: Scaling and root planing (SRP), Drug: Metronidazole 250 (7 days), Drug: Amoxicillin, Other: Placebo 250 (7 days) | Arm Label: MTZ 400 (7 days); Type: ACTIVE_COMPARATOR; Interventions: Procedure: Scaling and root planing (SRP), Drug: Metronidazole 400 (7 days), Drug: Amoxicillin, Other: Placebo 400 (7 days) | Arm Label: MTZ 250 (14 days); Type: ACTIVE_COMPARATOR; Interventions: Procedure: Scaling and root planing (SRP), Drug: Metronidazole 250 (14 days), Drug: Amoxicillin | Arm Label: MTZ 400 (14 days); Type: ACTIVE_COMPARATOR; Interventions: Procedure: Scaling and root planing (SRP), Drug: Metronidazole 400 (14 days), Drug: Amoxicillin | Intervention Type: PROCEDURE; Name: Scaling and root planing (SRP); Assigned to Arm(s): Control, MTZ 250 (14 days), MTZ 250 (7 days), MTZ 400 (14 days), MTZ 400 (7 days) | Intervention Type: DRUG; Name: Metronidazole 250 (7 days); Assigned to Arm(s): MTZ 250 (7 days) | Intervention Type: DRUG; Name: Metronidazole 400 (7 days); Assigned to Arm(s): MTZ 400 (7 days) | Intervention Type: DRUG; Name: Metronidazole 250 (14 days); Assigned to Arm(s): MTZ 250 (14 days) | Intervention Type: DRUG; Name: Metronidazole 400 (14 days); Assigned to Arm(s): MTZ 400 (14 days) | Intervention Type: DRUG; Name: Amoxicillin; Assigned to Arm(s): MTZ 250 (14 days), MTZ 250 (7 days), MTZ 400 (14 days), MTZ 400 (7 days) | Intervention Type: OTHER; Name: Placebo 250 (7 days); Assigned to Arm(s): MTZ 250 (7 days) | Intervention Type: OTHER; Name: Placebo 400 (7 days); Assigned to Arm(s): MTZ 400 (7 days) | Intervention Type: OTHER; Name: Placebo 400 (14 days); Assigned to Arm(s): Control | Intervention Type: OTHER; Name: Placebo 500; Assigned to Arm(s): Control
B: Arm Label: test; Type: EXPERIMENTAL; Interventions: Drug: Amoxicillin and Metronidazole | Arm Label: control; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Amoxicillin and Metronidazole; Assigned to Arm(s): test | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): control
C: Arm Label: Scaling and root planing alone; Type: PLACEBO_COMPARATOR; Interventions: Procedure: Scaling and root planing | Arm Label: SRP + Metronidazole; Type: ACTIVE_COMPARATOR; Interventions: Drug: Metronidazole | Arm Label: SRP + MET + Amoxicillin + Doxycycline; Type: ACTIVE_COMPARATOR; Interventions: Drug: Amoxicillin, Drug: Doxycycline | Intervention Type: PROCEDURE; Name: Scaling and root planing; Assigned to Arm(s): Scaling and root planing alone | Intervention Type: DRUG; Name: Metronidazole; Assigned to Arm(s): SRP + Metronidazole | Intervention Type: DRUG; Name: Amoxicillin; Assigned to Arm(s): SRP + MET + Amoxicillin + Doxycycline | Intervention Type: DRUG; Name: Doxycycline; Assigned to Arm(s): SRP + MET + Amoxicillin + Doxycycline
D: Arm Label: YH14642 A-I; Type: EXPERIMENTAL; Interventions: Drug: YH14642 500mg Tab | Arm Label: YH14642 A-II; Type: EXPERIMENTAL; Interventions: Drug: YH14642 500mg Tab | Arm Label: YH14642 A-III; Type: EXPERIMENTAL; Interventions: Drug: YH14642 500mg Tab | Arm Label: Active Comparator B; Type: ACTIVE_COMPARATOR; Interventions: Drug: INSADOL[Zea mays L. extract] 35mg Tab | Arm Label: Active Comparator C; Type: ACTIVE_COMPARATOR; Interventions: Drug: DENTISTA[Doxycycline hyclate] 20mg Cap | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: YH14642 500mg Tab; Assigned to Arm(s): YH14642 A-I | Intervention Type: DRUG; Name: YH14642 500mg Tab; Assigned to Arm(s): YH14642 A-II | Intervention Type: DRUG; Name: YH14642 500mg Tab; Assigned to Arm(s): YH14642 A-III | Intervention Type: DRUG; Name: INSADOL[Zea mays L. extract] 35mg Tab; Assigned to Arm(s): Active Comparator B | Intervention Type: DRUG; Name: DENTISTA[Doxycycline hyclate] 20mg Cap; Assigned to Arm(s): Active Comparator C | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo

Answer: B