Please select the eligibility criteria that correspond to the clinical trial below.
Title: Evaluation of the Effects of a Water Cure on Gonarthrosis: Randomized Clinical Study Including Water Cure Versus Continuation of the Usual Treatment
Brief Summary: The main objective of this study is to evaluate the therapeutic effect of a thermal treatment on gonarthrosis, with an increase of the number of patients presenting a clinically significant improvement.


Options:
A: Inclusion Criteria:

* Medial knee osteoarthritis
* Pain
* No foot problems
* Lives in Boston, Massachusetts Metro area
B: Inclusion Criteria:

* Radiographic evidence of hip or knee osteoarthritis
* Current / persistent joint symptoms (pain, aching, stiffness)

Exclusion Criteria:

* Other rheumatic disease (i.e., rheumatoid arthritis, fibromyalgia)
* Hospitalization for stroke or cardiovascular event within past 3 months
* Metastatic cancer
* Active diagnosis of psychosis
* Terminal illness
* On waiting list for arthroplasty
* Resident of nursing home
* Severely impaired in hearing or speech (participants must be able to respond to phone calls)
* Significant cognitive dysfunction
* No access to a telephone
* Current participation in another interventional study for osteoarthritis
C: Inclusion Criteria:

* ACR criteria: knee pain and one of the tree following conditions: Age \> 50 years, Morning stiffness\< 30 minutes and articular crackling.
* osteophytes visible on knee radiography.
* knee radiography less than 3 years old: face, schuss, axial of kneecap cliché.
* Actual gonarthrosis intensity on Visual Analogic Scale \> or = 30mm.

Exclusion Criteria:

* arthrosis limited to the femoro-patellar compartments.
* severe depressive syndrome, psychosis.
* Thermal cure less than 6 month before.
* Contra-indication or predictable inability to tolerate thermal cure.
* Profession lied to hydrotherapy.
* previous knee treatments:

  * massage, physiotherapy and acupuncture since less than 1 month;
  * infiltration since less than 3 months;
  * NSAI since less than 5 days;
  * analgesic since less than 12 hours;
  * modification in the medicinal anti-arthrosis treatment since less than 3 months.
D: Inclusion Criteria:

* a diagnosis of primary OA of the knee according to the ACR criteria, including radiologic evidence of OA
* age \>40 years
* symptomatic disease for at least 6 months prior to enrollment
* persistent pain despite receiving the maximum tolerated doses of conventional medical therapy, including acetaminophen (4 gm/day) and/or a nonsteroidal antiinflammatory drug (NSAID), with persistent pain defined as a minimum mean score of 25 mm on the visual analog scales (VAS) for global pain (0-100-mm range for each) daily pain during the month prior to study enrollment
* ability to attend followup appointments

Exclusion Criteria:

* secondary causes of OA
* local or systemic infection
* diabetes mellitus
* systemic arthritis
* allergy to anesthetic agent or contrast material
* coagulopathy
* anticoagulant therapy
* had previous IA steroid injection
* avascular necrosis of bone
* patients who are on specific OA pharmacological therapy (NSAIDS, opioids) for more than 2 weeks prior enrollment

Answer: C