TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Preventing Postpartum Hemorrhage: Examining Two Strategies for PPH Prevention in Communities: Misoprostol and Oxytocin Uniject in Senegal
Brief Summary: This is a large, community-based, cluster-randomized trial to compare routine prophylactic use of 600 mcg oral misoprostol and 10 IU oxytocin delivered by UnijectTM intramuscularly during the third stage of labor


Options:
A: Arm Label: Misoprostol; Type: EXPERIMENTAL; Interventions: Drug: Misoprostol | Arm Label: UnijectTM; Type: EXPERIMENTAL; Interventions: Device: UnijectTM | Intervention Type: DRUG; Name: Misoprostol; Assigned to Arm(s): Misoprostol | Intervention Type: DEVICE; Name: UnijectTM; Assigned to Arm(s): UnijectTM
B: Arm Label: Saline group; Type: EXPERIMENTAL; Interventions: Drug: Oxytocin | Intervention Type: DRUG; Name: Oxytocin; Assigned to Arm(s): Saline group
C: Arm Label: Misoprostol; Type: EXPERIMENTAL; Interventions: Drug: Misoprostol | Arm Label: PLACEBO; Type: PLACEBO_COMPARATOR; Interventions: Drug: Misoprostol | Intervention Type: DRUG; Name: Misoprostol; Assigned to Arm(s): Misoprostol, PLACEBO
D: Arm Label: oxytocin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Oxytocin | Arm Label: oxytocin2; Type: ACTIVE_COMPARATOR; Interventions: Drug: Oxytocin | Arm Label: oxytocin3; Type: ACTIVE_COMPARATOR; Interventions: Drug: Oxytocin | Intervention Type: DRUG; Name: Oxytocin; Assigned to Arm(s): oxytocin, oxytocin2, oxytocin3

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Preventing Postpartum Hemorrhage: Examining Two Strategies for PPH Prevention in Communities: Misoprostol and Oxytocin Uniject in Senegal
Brief Summary: This is a large, community-based, cluster-randomized trial to compare routine prophylactic use of 600 mcg oral misoprostol and 10 IU oxytocin delivered by UnijectTM intramuscularly during the third stage of labor


Options:
A: Arm Label: Short infusion; Type: EXPERIMENTAL; Interventions: Drug: Carbetocin Short-infusion | Arm Label: Bolus application; Type: OTHER; Interventions: Drug: Carbetocin Bolus application | Intervention Type: DRUG; Name: Carbetocin Short-infusion; Assigned to Arm(s): Short infusion | Intervention Type: DRUG; Name: Carbetocin Bolus application; Assigned to Arm(s): Bolus application
B: Intervention Type: DRUG; Name: Misoprostol; Assigned to Arm(s): N/A
C: Arm Label: Misoprostol; Type: EXPERIMENTAL; Interventions: Drug: Misoprostol | Arm Label: Oxytocin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Oxytocin | Intervention Type: DRUG; Name: Misoprostol; Assigned to Arm(s): Misoprostol | Intervention Type: DRUG; Name: Oxytocin; Assigned to Arm(s): Oxytocin
D: Arm Label: Misoprostol; Type: EXPERIMENTAL; Interventions: Drug: Misoprostol | Arm Label: UnijectTM; Type: EXPERIMENTAL; Interventions: Device: UnijectTM | Intervention Type: DRUG; Name: Misoprostol; Assigned to Arm(s): Misoprostol | Intervention Type: DEVICE; Name: UnijectTM; Assigned to Arm(s): UnijectTM

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Safety and Effectiveness Study of Percutaneous Catheter-based Renal Sympathetic Denervation in Patients With Drug-resistant Hypertension and Symptomatic Atrial Fibrillation
Brief Summary: To study whether renal sympathetic denervation(RSD) is safe and effective in patients with drug-resistant hypertension and symptomatic atrial fibrillation.


Options:
A: Arm Label: Intervention arm; Type: EXPERIMENTAL; Interventions: Device: Boston Scientific Vessix Renal Denervation System | Arm Label: Control arm; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: Boston Scientific Vessix Renal Denervation System; Assigned to Arm(s): Intervention arm
B: Arm Label: Renal denervation; Type: EXPERIMENTAL; Interventions: Device: MDT-2211 Renal Denervation System | Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: MDT-2211 Renal Denervation System; Assigned to Arm(s): Renal denervation
C: Arm Label: renal sympathetic denervation; Type: EXPERIMENTAL; Interventions: Procedure: renal sympathetic denervation, Drug: drug, Procedure: Direct-Current Cardioversion | Arm Label: drug therapy; Type: ACTIVE_COMPARATOR; Interventions: Drug: drug | Intervention Type: PROCEDURE; Name: renal sympathetic denervation; Assigned to Arm(s): renal sympathetic denervation | Intervention Type: DRUG; Name: drug; Assigned to Arm(s): drug therapy, renal sympathetic denervation | Intervention Type: PROCEDURE; Name: Direct-Current Cardioversion; Assigned to Arm(s): renal sympathetic denervation
D: Intervention Type: DEVICE; Name: Symplicty(TM) Catheter System; Assigned to Arm(s): N/A

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Safety and Effectiveness Study of Percutaneous Catheter-based Renal Sympathetic Denervation in Patients With Drug-resistant Hypertension and Symptomatic Atrial Fibrillation
Brief Summary: To study whether renal sympathetic denervation(RSD) is safe and effective in patients with drug-resistant hypertension and symptomatic atrial fibrillation.


Options:
A: Arm Label: Renal sympathetic denervation; Type: EXPERIMENTAL; Interventions: Device: Renal sympathetic denervation (Symplicity ablation catheter, Medtronic Inc. Minneapolis, Minnesota, USA) | Arm Label: Sham procedure; Type: SHAM_COMPARATOR; Interventions: Other: Sham procedure | Intervention Type: DEVICE; Name: Renal sympathetic denervation (Symplicity ablation catheter, Medtronic Inc. Minneapolis, Minnesota, USA); Assigned to Arm(s): Renal sympathetic denervation | Intervention Type: OTHER; Name: Sham procedure; Assigned to Arm(s): Sham procedure
B: Arm Label: Denervation; Type: EXPERIMENTAL; Interventions: Device: Ardian Symplicity™ Catheter | Intervention Type: DEVICE; Name: Ardian Symplicity™ Catheter; Assigned to Arm(s): Denervation
C: Arm Label: PV isolation; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Circumferential PV isolation | Arm Label: PV isolation+renal denervation; Type: ACTIVE_COMPARATOR; Interventions: Procedure: PV isolation+renal denervation | Intervention Type: PROCEDURE; Name: Circumferential PV isolation; Assigned to Arm(s): PV isolation | Intervention Type: PROCEDURE; Name: PV isolation+renal denervation; Assigned to Arm(s): PV isolation+renal denervation
D: Arm Label: renal sympathetic denervation; Type: EXPERIMENTAL; Interventions: Procedure: renal sympathetic denervation, Drug: drug, Procedure: Direct-Current Cardioversion | Arm Label: drug therapy; Type: ACTIVE_COMPARATOR; Interventions: Drug: drug | Intervention Type: PROCEDURE; Name: renal sympathetic denervation; Assigned to Arm(s): renal sympathetic denervation | Intervention Type: DRUG; Name: drug; Assigned to Arm(s): drug therapy, renal sympathetic denervation | Intervention Type: PROCEDURE; Name: Direct-Current Cardioversion; Assigned to Arm(s): renal sympathetic denervation

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Impact of Insecticide Resistance in Anopheles Arabiensis on the Effectiveness of Malaria Vector Control in Sudan
Brief Summary: The purpose of the study is to determine whether long lasting insecticidal nets and indoor residual insecticide spraying, alone or in combination, are effective for controlling insecticide resistant anopheles mosquitoes for malaria prevention.


Options:
A: Arm Label: Conventional Olyset LLIN; Type: EXPERIMENTAL; Interventions: Other: Conventional Olyset LLIN | Arm Label: Olyset Plus LLIN; Type: EXPERIMENTAL; Interventions: Other: Olyset Plus LLIN | Arm Label: Conventional Olyset LLIN and IRS; Type: EXPERIMENTAL; Interventions: Other: Conventional Olyset LLIN, Other: IRS | Arm Label: Olyset Plus LLIN and IRS; Type: EXPERIMENTAL; Interventions: Other: Olyset Plus LLIN, Other: Conventional Olyset LLIN | Intervention Type: OTHER; Name: Olyset Plus LLIN; Assigned to Arm(s): Olyset Plus LLIN, Olyset Plus LLIN and IRS | Intervention Type: OTHER; Name: Conventional Olyset LLIN; Assigned to Arm(s): Conventional Olyset LLIN, Conventional Olyset LLIN and IRS, Olyset Plus LLIN and IRS | Intervention Type: OTHER; Name: IRS; Assigned to Arm(s): Conventional Olyset LLIN and IRS
B: Arm Label: LLIN plus IRS; Type: EXPERIMENTAL; Interventions: Other: Indoor residual spraying with bendiocarb, Other: LLIN by universal coverage campaign | Arm Label: LLIN only; Type: ACTIVE_COMPARATOR; Interventions: Other: LLIN by universal coverage campaign | Intervention Type: OTHER; Name: Indoor residual spraying with bendiocarb; Assigned to Arm(s): LLIN plus IRS | Intervention Type: OTHER; Name: LLIN by universal coverage campaign; Assigned to Arm(s): LLIN only, LLIN plus IRS
C: Arm Label: Universal coverage of Long Lasting Insecticidal Nets (LLIN); Type: ACTIVE_COMPARATOR; Interventions: Device: Long Lasting Insecticidal Nets (LLIN) | Arm Label: LLIN Plus Indoor Residual Spraying; Type: EXPERIMENTAL; Interventions: Other: Indoor residual insecticide spraying (IRS), Device: Long Lasting Insecticidal Nets (LLIN) | Intervention Type: OTHER; Name: Indoor residual insecticide spraying (IRS); Assigned to Arm(s): LLIN Plus Indoor Residual Spraying | Intervention Type: DEVICE; Name: Long Lasting Insecticidal Nets (LLIN); Assigned to Arm(s): LLIN Plus Indoor Residual Spraying, Universal coverage of Long Lasting Insecticidal Nets (LLIN)
D: Arm Label: IRS; Type: EXPERIMENTAL; Interventions: Other: Actellic CS | Arm Label: non-IRS; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Actellic CS; Assigned to Arm(s): IRS

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Surgical Site Infection Rates of Two Different Skin Closure Methods Used in Obese Patients After Cesarean Delivery
Brief Summary: The aim of this study is to determine the surgical site infection rate and patient satisfaction for subcuticular versus interrupted mattress suture in closure of skin at Cesarean delivery in obese patients.


Options:
A: Arm Label: Stainless Steel Staples; Type: ACTIVE_COMPARATOR; Interventions: Device: Stainless steel staples | Arm Label: 4-0 monofilament Sutures; Type: EXPERIMENTAL; Interventions: Device: 4-0 monofilament suture | Intervention Type: DEVICE; Name: 4-0 monofilament suture; Assigned to Arm(s): 4-0 monofilament Sutures | Intervention Type: DEVICE; Name: Stainless steel staples; Assigned to Arm(s): Stainless Steel Staples
B: Arm Label: Interrupted suturing Group; Type: ACTIVE_COMPARATOR; Interventions: Other: Interrupted suturing | Arm Label: Subcuticular suturing Group; Type: ACTIVE_COMPARATOR; Interventions: Other: Subcuticular suturing | Intervention Type: OTHER; Name: Interrupted suturing; Assigned to Arm(s): Interrupted suturing Group | Intervention Type: OTHER; Name: Subcuticular suturing; Assigned to Arm(s): Subcuticular suturing Group
C: Arm Label: Staple Closure; Type: EXPERIMENTAL; Interventions: Procedure: Staple Closure | Arm Label: Running Subcuticular Closure; Type: EXPERIMENTAL; Interventions: Procedure: Running Subcuticular Closure | Arm Label: Vertical Mattress Closure; Type: EXPERIMENTAL; Interventions: Procedure: Vertical Mattress Closure | Intervention Type: PROCEDURE; Name: Staple Closure; Assigned to Arm(s): Staple Closure | Intervention Type: PROCEDURE; Name: Vertical Mattress Closure; Assigned to Arm(s): Vertical Mattress Closure | Intervention Type: PROCEDURE; Name: Running Subcuticular Closure; Assigned to Arm(s): Running Subcuticular Closure
D: Arm Label: Chinese Silk Suture; Type: ACTIVE_COMPARATOR; Interventions: Device: silk suture | Arm Label: VICRYL* Plus Suture; Type: EXPERIMENTAL; Interventions: Device: VICRYL* Plus suture | Intervention Type: DEVICE; Name: silk suture; Assigned to Arm(s): Chinese Silk Suture | Intervention Type: DEVICE; Name: VICRYL* Plus suture; Assigned to Arm(s): VICRYL* Plus Suture

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Utility of a Clinically Relevant Decision Aid, for Parents Facing Extremely Premature Delivery
Brief Summary: The purpose of this study is to assess in a pilot randomized controlled trial the following PICOT question: In parents facing extreme premature delivery, does the use of an existing validated visual decision aid as compared to standard counseling, reduce the primary outcome of parental decisional conflict? Furthermore, is such a decision aid understood and applicable across differing populations of different ethnic backgrounds and social classes?


Options:
A: Arm Label: Decision Aid; Type: OTHER; Interventions: Other: Decision Aid | Arm Label: Standard; Type: OTHER; Interventions: Other: Standard | Intervention Type: OTHER; Name: Decision Aid; Assigned to Arm(s): Decision Aid | Intervention Type: OTHER; Name: Standard; Assigned to Arm(s): Standard
B: Arm Label: Counseling; Type: EXPERIMENTAL; Interventions: Behavioral: Extra counseling | Arm Label: Standard care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Extra counseling; Assigned to Arm(s): Counseling
C: Arm Label: Standard ACP/Patient Alone; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Standard advance care planning | Arm Label: Decision Aid/Patient Alone; Type: EXPERIMENTAL; Interventions: Behavioral: Making Your Wishes Known | Arm Label: Standard ACP/Together; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Standard advance care planning | Arm Label: Decision Aid/Together; Type: EXPERIMENTAL; Interventions: Behavioral: Making Your Wishes Known | Intervention Type: BEHAVIORAL; Name: Making Your Wishes Known; Assigned to Arm(s): Decision Aid/Patient Alone, Decision Aid/Together | Intervention Type: BEHAVIORAL; Name: Standard advance care planning; Assigned to Arm(s): Standard ACP/Patient Alone, Standard ACP/Together
D: Arm Label: FRAX + Decision Aid; Type: EXPERIMENTAL; Interventions: Behavioral: FRAX + Decision Aid | Arm Label: Usual care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: FRAX estimated fracture risk; Type: EXPERIMENTAL; Interventions: Behavioral: FRAX estimated fracture risk | Intervention Type: BEHAVIORAL; Name: FRAX + Decision Aid; Assigned to Arm(s): FRAX + Decision Aid | Intervention Type: BEHAVIORAL; Name: FRAX estimated fracture risk; Assigned to Arm(s): FRAX estimated fracture risk

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Acute Effects of Exercise on the Cortical Silent Period in Prostate Cancer Patients
Brief Summary: In Canadian men, prostate cancer (PCa) is the most prevalent form of cancer and the third leading cause of cancer-related death. Unfortunately, PCa survivors are often burdened with feelings of anxiety and depression associated with the disease and associated treatments. Short-term exercise interventions (8-24 weeks) have improved psychosocial well-being in this population, but the impact of single bouts of exercise and related psychological or neurological changes have never been studied. The primary objective of the proposed study is to examine the effect of an acute bout of exercise on neurophysiological and psychological indicators of well-being in a randomized controlled trial (RCT) of 36 men with PCa. Participants will be randomly assigned to the intervention (60 min exercise) or control (60 min of television) and will undergo a brief neurological test (cortical silent period) and psychological questionnaires before and after their group assignment.


Options:
A: Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Exercise; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise | Intervention Type: BEHAVIORAL; Name: Exercise; Assigned to Arm(s): Exercise
B: Arm Label: Linear Aerobic Training; Type: EXPERIMENTAL; Interventions: Behavioral: Linear Aerobic Training, Other: Cardiopulmonary exercise test (CPET), Other: Blood draws | Arm Label: Nonlinear Aerobic Training; Type: EXPERIMENTAL; Interventions: Behavioral: Nonlinear Aerobic Training, Other: Cardiopulmonary exercise test (CPET), Other: Blood draws | Arm Label: Progressive Stretching Group (Attention control); Type: EXPERIMENTAL; Interventions: Behavioral: Progressive Stretching, Other: Cardiopulmonary exercise test (CPET), Other: Blood draws | Intervention Type: BEHAVIORAL; Name: Linear Aerobic Training; Assigned to Arm(s): Linear Aerobic Training | Intervention Type: BEHAVIORAL; Name: Nonlinear Aerobic Training; Assigned to Arm(s): Nonlinear Aerobic Training | Intervention Type: BEHAVIORAL; Name: Progressive Stretching; Assigned to Arm(s): Progressive Stretching Group (Attention control) | Intervention Type: OTHER; Name: Cardiopulmonary exercise test (CPET); Assigned to Arm(s): Linear Aerobic Training, Nonlinear Aerobic Training, Progressive Stretching Group (Attention control) | Intervention Type: OTHER; Name: Blood draws; Assigned to Arm(s): Linear Aerobic Training, Nonlinear Aerobic Training, Progressive Stretching Group (Attention control)
C: Arm Label: Exercise; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise | Arm Label: Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Exercise; Assigned to Arm(s): Exercise
D: Arm Label: Patients Pre and Post-chemotherapy; Type: N/A; Interventions: N/A

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Acute Effects of Exercise on the Cortical Silent Period in Prostate Cancer Patients
Brief Summary: In Canadian men, prostate cancer (PCa) is the most prevalent form of cancer and the third leading cause of cancer-related death. Unfortunately, PCa survivors are often burdened with feelings of anxiety and depression associated with the disease and associated treatments. Short-term exercise interventions (8-24 weeks) have improved psychosocial well-being in this population, but the impact of single bouts of exercise and related psychological or neurological changes have never been studied. The primary objective of the proposed study is to examine the effect of an acute bout of exercise on neurophysiological and psychological indicators of well-being in a randomized controlled trial (RCT) of 36 men with PCa. Participants will be randomly assigned to the intervention (60 min exercise) or control (60 min of television) and will undergo a brief neurological test (cortical silent period) and psychological questionnaires before and after their group assignment.


Options:
A: Arm Label: Exercise; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Physical exercise, Other: best supportive care | Arm Label: No exercise; Type: OTHER; Interventions: Other: best supportive care | Intervention Type: BEHAVIORAL; Name: Physical exercise; Assigned to Arm(s): Exercise | Intervention Type: OTHER; Name: best supportive care; Assigned to Arm(s): Exercise, No exercise
B: Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Exercise; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise | Intervention Type: BEHAVIORAL; Name: Exercise; Assigned to Arm(s): Exercise
C: Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Study Group; Type: EXPERIMENTAL; Interventions: Other: Domiciliary exercises for the upper limbs | Intervention Type: OTHER; Name: Domiciliary exercises for the upper limbs; Assigned to Arm(s): Study Group
D: Arm Label: Training Group; Type: EXPERIMENTAL; Interventions: Other: Exercise | Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Exercise; Assigned to Arm(s): Training Group

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Physiological Effect of Sulforaphane Obtained From Broccoli Sprouts Homogenates (BSH) on the HbF and Anti-oxidative Capacity of Human Sickle Red Blood Cells (SS RBC)
Brief Summary: The overall purpose of this study is to obtain a better understanding of the biological response of red blood cells to sulforaphane contained in fresh broccoli sprouts that have been put through a blending process. This study will use commercially available fresh broccoli sprouts certified by Brassica Protection Products LLC (BroccoSprouts®). This product can also be purchased at some local grocery stores in the produce section. It is believed that NRF2, a transcription factor encoded by the NFE2L2 gene, plays a role in the regulation of defense against oxidative stress. The detrimental accelerated breakdown of sickle cell disease (SCD) red blood cells (SS RBC) is partially due to reduced anti-oxidative capacity. Previous analysis of SS RBC microRNAs revealed that a reduced level of NRF2, the master regulator of anti-oxidative stress capacity, contributes to reduced resistance to oxidative stress and increased hemolysis; NRF2 also induces fetal hemoglobin (HbF), which is known to prevent SS RBC sickling.

First, erythroid progenitors from normal and SCD subjects will be tested ex-vivo to find out how sulforaphane, a natural NRF2 activator, affects the oxidative stress capacity, HbF expression, and microRNA expression of red cells.

Second, a pilot clinical trial will be conducted to determine the safety and physiological effects of 3 weeks of daily consumption of broccoli sprout homogenate in a cohort of Hb SS/SB0 thalassemia adult SCD patients. During this study, subjects RBCs will be assayed for changes in anti-oxidative stress capacity and microRNA composition in mature SCD red blood cells.


Options:
A: Arm Label: Broccoli sprout homogenate ingestion; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Broccosprouts® (Brassica Protection Products LLC) homogenate | Intervention Type: DIETARY_SUPPLEMENT; Name: Broccosprouts® (Brassica Protection Products LLC) homogenate; Assigned to Arm(s): Broccoli sprout homogenate ingestion
B: Arm Label: Hydroxyurea; Type: ACTIVE_COMPARATOR; Interventions: Drug: Hydroxyurea | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Hydroxyurea; Assigned to Arm(s): Hydroxyurea | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
C: Arm Label: Intrevention arm; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Gum Arabic | Intervention Type: DIETARY_SUPPLEMENT; Name: Gum Arabic; Assigned to Arm(s): Intrevention arm
D: Arm Label: Cannabis; Type: EXPERIMENTAL; Interventions: Drug: Cannabis | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Cannabis | Intervention Type: DRUG; Name: Cannabis; Assigned to Arm(s): Cannabis, Placebo

Answer: A