TrialPanorama/Dataset huggingface dataset:
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Clinical and Economic Assessment of an Opportunistic Screening Program for Pre-frailty State in Elderly Population.
Brief Summary: The study intervention improves functional capacity and delays frailty status in pre-frail elderly subjects.


Options:
A: Inclusion Criteria:

* More than 70 years consulting in primary care
* Non institutionalized
* Pre-frailty according to L.Fried criteria (1 or 2 criteria)
* Signed informed consent

Exclusion Criteria:

* Patient not able to stand by himself/herself
* Dementia
* Palliative care or life expectancy less than 6 months
* Blind patient
* unstable clinical situation
* Participation in other programs, studies or trials for elderly people
B: Inclusion Criteria:

* Community-dwelling older adults, men and women aged 60 and over who have fallen at least once in the last 12 months

Exclusion Criteria:

* A previous diagnosis of dementia or a cognitive decline;
* A previous stroke with a severe neurological impairment;
* A progressive neurological disease;
* A severe visual deficiency;
* Any acute illness that the physician considers as an exercise contra-indication;
* An acute vertigo or dizziness less than 3 months duration;
* Inability to keep on standing, even with the use of a walking aid or other device;
* Unable to communicate;
* Those who are engaged in a regular exercise program, including physical therapy, with a frequency of equal to or more than twice a week such as: muscle strengthening, balance or gait exercise, Tai Chi and Yoga
C: Inclusion Criteria:

* 55 years of age or older
* independent living within the city of Sault Ste. Marie, Ontario, Canada
* capable of providing informed consent

Exclusion Criteria:

* not at risk for falls
* unable to give informed consent
D: Inclusion Criteria:

* female
* age 70-80 years old
* lives at home independently
* has fallen at least once during the previous year
* no contraindication to exercise
* understands the procedures of the study
* has been informed of X-ray radiation doses of the DXA and pQCT investigations

Exclusion Criteria:

* moderate-to-vigorous exercise more than 2 hours per week
* regular use of vitamin D, or calcium + vitamin D supplements
* a recent fracture (during preceding 12 months)
* contraindication or inability to participate in the exercise program
* marked decline in the basic activities of daily living (ADL-test)
* cognitive impairments (Mini Mental State Examination, MMSE-test \< 18)
* persons with chronic disease conditions, such as Parkinson's disease

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Improving Consent and Survey Procedures for Young MSM in Web-based HIV Prevention
Brief Summary: A two-part study to test the efficacy of alternative consent procedures and the efficacy of alternative methods to improve survey completion.


Options:
A: Inclusion Criteria:

* Adolescents/young adults aged 11-21 years
* Physician diagnosis of CKD stage 1-4
* Currently prescribed an antihypertensive medication and anticipate staying on an antihypertensive through the study duration (switching medication classes is permitted)
* Must have daily access to a Wi-Fi-enabled electronic device (e.g. iOS, Android 4.2 or higher, phone, tablet, computer) to receive private health information.

Exclusion Criteria:

* Adolescents/young adults who are on dialysis or had a kidney transplant
* Sibling participating in the study, unable to comprehend spoken English
* Cognitive delay precluding completion of study procedures
* And prescribed a liquid form of an antihypertensive medication (cannot be monitored).
B: Inclusion Criteria:

* ages 18-34
* have had sex with another man in the past 12 months

Exclusion Criteria:

* female, transgender
* younger than 18 years old
* older than 34 years old
* have not had sex with a man in the past 12 months
C: Inclusion Criteria:

* Participants are taken from an established intervention study aiming at creating network for different groups of vulnerable children and youth aged 10-23 years. The groups comprise: children in foster care, former foster youth, children of mental ill parents, children of parents with alcohol abuse and children raised in violent families. Participants who have given informed consent to take part in the evaluation of the established intervention study and thereby agree to fill out questionnaires and report their unique personal identification number are eligible to take part in the study.

Exclusion Criteria:

* Based on the participants unique personal identification number (CPR-number in the Danish Civil Registration System) the Central Office of Civil Registration will provide us with addresses of the participants. Participants, who are not available in the Civil Register either because participants are dead, immigrated or have requested survey exemption, are excluded from the study. Participants who have reported incomplete identification number will also be excluded.
D: Inclusion Criteria:

* individuals (including institutionalized individuals) aged 16 years or older and resident in Denmark per 1 January 2017.

Exclusion Criteria:

-

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Sustained Aeration of Infant Lungs Trial
Brief Summary: This study is a 2-arm randomized, controlled, multi-center clinical trial to determine which of two strategies at birth are best to optimally aerate the lung of preterm infants. Specifically we will determine in 600 infants of 23-26 weeks gestational age (GA) requiring respiratory support at birth which of two lung opening strategies - either a standard PEEP/CPAP of 5-7 cm H2O in the delivery room (DR), as compared to early lung recruitment using Sustained Inflation (SI) in the DR, will result in a lower rate of the combined endpoint of death or bronchopulmonary dysplasia (BPD) at 36 weeks gestational age.

Hypotheses:

1. Early lung recruitment with SI superimposed upon standard PEEP/CPAP in the DR will reduce the need for mechanical ventilation in the first seven days of life, and reduce need for surfactant use; and
2. A policy of DR SI on standard PEEP/CPAP recruitment will confer better outcomes at 36 weeks post-menstrual age (PMA) than standard PEEP/CPAP


Options:
A: Inclusion Criteria:

Newborn infants with asystole Newborn infants with bradycardia

Exclusion Criteria:

-
B: Inclusion Criteria:

* Infants (term or preterm infants \>28 weeks' gestation) requiring CC in the delivery room will be eligible for the trial.

Exclusion Criteria:

* Infants will be excluded if they have a congenital abnormality or condition that might have an adverse effect on breathing or ventilation (e.g. congenital diaphragmatic hernia), or congenital heart disease requiring intervention in the neonatal period. Infants would be also excluded if their parents refused to give consent to this study.
C: Inclusion Criteria:

* Gestational age (GA) at least 23 weeks but less than 27 completed weeks by best obstetrical estimate
* Requiring resuscitation/respiratory intervention at birth -"apneic, labored breathing, gasping" (as defined in NRP 2011 AAP 6th Edition p.45)

Exclusion Criteria:

* Considered non-viable by the attending neonatologist
* Refusal of antenatal informed consent
* Known major anomalies, pulmonary hypoplasia
* Mothers who are unable to consent for their medical care and who do not have a surrogate guardian will not be approached for consent
D: Inclusion Criteria:

* Infants \<33 weeks gestation born in the Royal Alexandra Hospital who require respiratory support for resuscitation in the delivery room.

Exclusion Criteria:

* Infants will be excluded if they have a congenital abnormality or condition that might have an adverse effect on breathing or ventilation, e.g. congenital pulmonary or airway anomalies, congenital diaphragmatic hernia, or congenital heart disease requiring intervention in neonatal period. Infants will also be excluded if their parents refuse to give consent to this study.

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Enhancing Housing First Programs With a Social Network Substance Use Intervention
Brief Summary: Housing First programs are promising approaches to transitioning substance using chronically homeless adults to affordable housing. However, Housing First programs need to provide support to residents to adjust to their changing social environments. The proposed project fulfills a critical gap by developing an electronic tool for a social network intervention using motivational interviewing techniques as well as results of a pilot test of the tool. The hypothesis to be tested is that Housing First residents who are given the intervention will be significantly more motivated to change their drinking, drug use, sexual risk behaviors, and social networks compared to controls receiving usual care.


Options:
A: Inclusion Criteria:

* patient is 18 years or older
* Alcohol and/or Drug screening score that indicates at least mild problem severity.

Exclusion Criteria:

* medical or psychiatric complications
* substance use is mild enough that further intervention is not warranted
* patient reports plans to leave the area within the next 12 months
* patient is unable to provide valid informed consent
B: Inclusion Criteria:

* HCV antibody positive
* age between 18 and 35 years old;
* reported injection drug use in the past 6 months
* willing to provide a blood sample for liver function testing

Exclusion Criteria:

* HIV antibody positive
* planned on moving from city within the next 12 months;
* unable to comprehend English well enough to complete English-only assessments and group sessions
C: Inclusion Criteria:

* New residents of Skid Row Housing Trust receiving permanent supportive housing

Exclusion Criteria:

* Age younger than 18
* Does not speak English
* Cognitively impaired either by identifying those having a diagnosis of dementia in the new resident intake interview or using the Short Blessed Scale Exam)
* Does not screen positive for past -year harmful AOD use using the AUDIT-C (a score \> 4 for men and \> 3 for women) and DAST (a score greater than 2).
D: Inclusion Criteria:

1. homeless males self-reporting gay or bisexual behaviors in the last 12 months
2. age 18-39
3. methamphetamine and/or cocaine/crack use currently or in the last three months
4. no self-reported participation in drug treatment in the last 30 days
5. willing to provide informed consent
6. willing to undergo hepatitis B and C and HIV antibody testing at baseline
7. found to be HBV antibody negative

Exclusion Criteria:

1. persons with Guillian Barre, or allergy to yeast or neomycin
2. monolingual speakers of languages other than English or Spanish
3. persons judged to be cognitively impaired by the nurse

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Comparative Study Between Duct to Mucosa and Invagination Pancreaticojejunostomy After Pancreaticoduodenectomy: A Prospective Randomized Study
Brief Summary: Postoperative pancreatic fistula (POPF) remains a challenge even at specialized centers, and also affect significantly the surgical outcomes . The incidence of POPF after pancreaticoduodenectomy among different studies, ranging from 5 to 30%.Morbidity and mortality after pancreaticoduodenectomy are usually related to surgical management of the pancreatic stump. The safe pancreatic reconstruction after pancreaticoduodenectomy continues to be a challenge at high volume centers. The variety of reconstruction is a reflection of the lack of ideal one.Duct to mucosa and invagination are two classic PJ techniques. Many studies compared both techniques, but their surgical outcomes still unclear.The aim of the study was to assess the effectiveness and surgical outcomes of both techniques of PJ after pancreaticoduodenectomy.


Options:
A: Inclusion Criteria:

Patients from whom we obtained written informed consent of this study

Exclusion Criteria:

* Patients with severe ischemic cardiac disease
* Patients with severe liver damage
* Patients requiring oxygen administration due to interstitial pneumonia or pulmonary fibrosis
* Patients requiring dialysis treatment due to chronic renal failure
* Patients who are considered as inappropriate by attending physician
B: Inclusion Criteria:

-Consecutive patients who were treated by pancreaticoduodenectomy

Exclusion Criteria:

* Any patients with locally advanced periampullary tumour, metastases
* Patients received neoadjuvant chemoradiotherapy
* Patients underwent pancreaticogastrostomy (PG)
* Patients with advanced liver cirrhosis (Child B or C)
* Malnutrition
* Coagulopathy
C: Inclusion Criteria:

* Patients must have undergone pancreaticoduodenectomy.
* Must have pancreatic remnant remaining in place (body and tail).
* Must be candidate for reconstruction by pancreaticojejunostomy by one of the two techniques described below.
* Must have an identifiable pancreatic duct which can be used for a duct-to-mucosa anastomosis.

Exclusion Criteria:

* Patients undergoing total pancreatectomy.
* Patients undergoing PD who have had previous left-sided pancreatic resection.
* Failure to sign informed consent.
* Failure to identify the pancreatic duct.
* Pregnant patients.
D: Inclusion Criteria:

* Informed consent
* 18-80 years old;
* Eastern Cooperative Oncology Group(ECOG) 0-2
* Patients must have undergone pancreaticoduodenectomy.
* Preoperative enhanced CT scan shows respectable or borderline resectable neoplasm
* Without distal metastasis

Exclusion Criteria:

* Patients who have had previous pancreatic body tail resection rese
* immunodeficiency, people infected with HIV
* patients with severe cardiopulmonary function, liver and renal function
* infection without control or active infections
* Pregnant patients.

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: A Randomized, Double-Blind, Placebo-Controlled, Parallel, 3-Arm Study of the Safety and Anti-Pruritic Efficacy of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus
Brief Summary: The primary objectives of the study to evaluate the effects of two doses of nalbuphine HCl ER tablets on the change from baseline in the worst itch Numerical Rating Scale (NRS) in hemodialysis patients with moderate to severe uremic pruritus and to evaluate the safety and tolerability in the study population.


Options:
A: Inclusion Criteria:

* 18 yrs old or older
* moderate to severe pruritus
* end stage renal disease
* 3x weekly hemodialysis

Exclusion Criteria:

* pruritus not due to renal disease
* abnormal liver function
* Ca-P \> 80 mg/dl or HgB \<8.5 g/dl or PTH \> pg/mL
* Within four months spKt/V \< 1.05
B: Inclusion Criteria:

* Subject has been receiving in-center hemodialysis for ≥ 3 months and are currently on a schedule of 3 times a week.
* Subject self-categorized themselves on the Patient Assessed Disease Severity Scale during Screening
* Subject meets standard of care hemodialysis efficiency guidelines during the three months prior to completing Screening
* Have demonstrated pruritus intensity on the Itch NRS during screening
* Male or female who are at least 18 years old at the time of Screening

Exclusion Criteria:

* Subject had a significant alteration in dialysis regimen during the Screening Period
* Subject receiving or anticipated to be receiving nocturnal dialysis or home hemodialysis treatment during the study.
* Subject has pruritus that is believed to be caused by a condition unrelated to end-stage renal disease
* Has had a history of substance abuse within 6 months prior to completing Screening
* Subject has a known drug allergy to opioids
* Subject is a pregnant or lactating female.
C: Inclusion Criteria:

* Hemodialysis patients
* Suffering from pruritus for at least 6 weeks
* Have not responded to other drugs
* visual analogue scale (VAS) equal or more than 4

Exclusion Criteria:

* Liver disease
* Respiratory disease
* Dermatological disease
* Hemoglobin less than 10
* Cholestasis
* Malignancies
D: Inclusion Criteria:

* Willingness to sign an informed consent
* Stable haemodialysis treatment for more than 3 months, undergoing 2 to 3 times haemodialysis a week for 4 to 5 hours per session
* middle or large molecules retention defined as immunoreactive parathyroid hormone (iPTH) \> 400 pg/mL, β2MG\>5000 pg/ml、CRP\>10mg/l.
* Refractory pruritus, carpal tunnel syndrome, restless leg syndrome, hyperparathyroidism or other refratory complications.

Exclusion Criteria:

* Incapable or reluctant to sign the informed consent or comply the schedule.
* platelet (PLT) count\<60×109/L or disturbance in coagulation, tendency of severe bleeding or acute bleeding.
* Severe hypotension and heart or lung insufficiency
* Known hypersensitive or contradiction or intolerance to dialyzer or adsorbents
* Attend to other clinic trial now or in recent 30 days

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Pregnancy Outcomes in Women With Unexplained Recurrent Pregnancy Loss Treated With Low Dose Aspirin and Unfractionated Heparin
Brief Summary: Objective To determine maternal and fetal outcomes in women with Unexplained RPL managed with aspirin or unfractionated heparin (UFH) plus aspirin during pregnancy.

Design: prospective clinical controlled study. Setting: high-risk pregnancy unit- Benha university hospital. Methods: Pregnant women with unexplained recurrent miscarriage attending high-risk pregnancy unit. 200 selected patients with previous unexplained recurrent miscarriage are divided into 2 groups: group A (n = 100) receive low-dose aspirin (81 mg once daily orally) plus heparin (5000 IU) every 12 h with the ﬁrst positive pregnancy test while group B (n = 100) receive no thing .

Main outcome measures: Maternal outcomes included thromboembolic and haemorrhagic complications and pregnancy-induced hypertension .Prematurity, intrauterine growth restriction and neonatal death were considered as maternal and fetal complications


Options:
A: Inclusion Criteria:

* history of two or more unexplained consecutive pregnancy losses prior to 32 weeks
* presence of one of the panel of autoantibodies/thrombophilia markers
* confirmed pregnancy

Exclusion Criteria:

* SLE
* known peptic ulcer disease
* sensitivity to ASA or heparin
* previous thrombotic event
* geographic distance from clinic
* failure to consent
B: Inclusion Criteria:

* Habenox 1: Three or more consecutive abortions of first trimester (ad h 12+6 wks) or two second trimester abortions (ad h 13 wks-23+6 wks) or one third trimester abortion (24 weeks or more) with one first-second trimester abortions and one thrombophiliatest positive: F V Leiden (heterozygote) or protein C or S deficiency, or anticardiolipin antibodies (low to moderate level), prothrombin gene mutation, or high level of F VIII.
* HABENOX 2: The thrombophilic tests above are negative.
* HABENOX 3:positive combined thrombophilia, F V Leiden (homozygote), anticardiolipin antibodies (high level \>40) , lupusanticoagulant, or AT III deficiency.

Exclusion Criteria:

* History of DVT or pulmonary embolism.
* Significant bleeding history.
C: Inclusion Criteria:

* patients with unexplained recurrent pregnancy loss (RPL)

Exclusion Criteria:

* previous history of Diabetes Mellitus or thyroid dysfunction or cardiac disease
* Thrombocytopenia (\<100000/ml)
* bleeding tendencies
* ectopic pregnancy
* past history of vascular thrombosis
* uterine anomalies
* multiple gestation
D: Inclusion Criteria:

* gestational age before 20th
* low risk pregnancy

Exclusion Criteria:

* high magnesium serum

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Nutrition and Physical Activity Policies, Obesogenic Behaviors and Weight Outcomes
Brief Summary: The investigators long-term goal is to advance the adoption and successful implementation of policies that promote PA and nutrition in after school programs (ASP) nationwide. The investigators objective here is two fold. First, the investigators will test the effectiveness of two promising strategies designed to 1) increase the amount of PA children accumulate while attending an ASP and 2) promote changes in the nutritional quality of the snacks served. This represents a fundamental step in establishing practice-based guidelines (best practices) for the uptake and achievement of public health policy goals (CA and Harvard). Second, the investigators will examine the barriers and facilitators to implementing these strategies. The expected outcome of this study is evidence supporting best practices for ASPs to employ to meet policy goals.


Options:
A: Inclusion Criteria:

Programs that:

* Operate immediately after the school day
* Operate every day of the school year for a minimum of 2 hours
* Serve a minimum of 30 children of elementary age (6-12 years)
* Operate in a school, community or faith Setting
* Provide a snack
* Provide homework assistance/completion time
* Provide enrichment
* Provide opportunities for physical activity
* All children enrolled, staff, and afterschool program (ASP) leaders in the ASPs were eligible to participate in the study.

Exclusion Criteria:

* Programs that:
* Were singularly focused
* Programs that were physical activity focused

Children that:

* Have any physical and/or orthopedic impairment that would limit a child's ability to participate in regular physical activity.
B: Inclusion Criteria:

* student's informed consent and an approval from his/her parent

Exclusion Criteria:

* no informed consent from the student and no approval from his/her parent
C: Inclusion Criteria:

grade of 1 to 5 in primary schools and grade of 6 to 8 and 10 to 11 in secondary schools.

Exclusion Criteria:

Suffering or any history of disabilities, cardiovascular diseases, asthma, metabolic diseases, etc.
D: Inclusion Criteria:

* Participating schools need to meet the following eligibility criteria: (1) were within provincial jurisdiction, (2) had a minimum of 200 students per school, (3) offered grades 1 through 6.

Exclusion Criteria:

* Children will be excluded if consent was not received from parents or if they had a condition that limited participation in physical activity.

Answer: A