Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Effects of Long Term Inhalation of Hypertonic Saline in Subjects With Cystic Fibrosis
Brief Summary: The effect of long term inhalation of hypertonic saline in subjects with cystic fibrosis on lung function, incidence of respiratory tract infections, quality of life, quantitative microbiology and sputum cytokine profile. The hypothesis is that regular inhalation of nebulised hypertonic saline will have a beneficial effect on lung function and other clinical outcomes with no adverse effects on infection and inflammation in adults and children with cystic fibrosis.


Options:
A: Arm Label: All meds but depression, 1x daily use, RxTimerCap; Type: EXPERIMENTAL; Interventions: Behavioral: RxTimerCap | Arm Label: All meds but depression, 1x daily use, Take-N-Slide; Type: EXPERIMENTAL; Interventions: Behavioral: Take-N-Slide | Arm Label: All meds but depression, 1x daily use, pillbox; Type: EXPERIMENTAL; Interventions: Behavioral: Pillbox | Arm Label: All meds but depression, 1x daily use, control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: All meds but depression, ≥1 med >1 daily use, RxTimerCap; Type: EXPERIMENTAL; Interventions: Behavioral: RxTimerCap | Arm Label: All meds but depression, ≥1 med >1 daily use, pillbox; Type: EXPERIMENTAL; Interventions: Behavioral: Pillbox | Arm Label: All meds but depression, ≥1 med >1 daily use, control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Only depression meds, 1x daily use, RxTimerCap; Type: EXPERIMENTAL; Interventions: Behavioral: RxTimerCap | Arm Label: Only depression meds, 1x daily use, Take-N-Slide; Type: EXPERIMENTAL; Interventions: Behavioral: Take-N-Slide | Arm Label: Only depression meds, 1x daily use, pillbox; Type: EXPERIMENTAL; Interventions: Behavioral: Pillbox | Arm Label: Only depression meds, 1x daily use, control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Only depression meds, ≥1 med >1 daily use, RxTimerCap; Type: EXPERIMENTAL; Interventions: Behavioral: RxTimerCap | Arm Label: Only depression meds, ≥1 med >1 daily use, pillbox; Type: EXPERIMENTAL; Interventions: Behavioral: Pillbox | Arm Label: Only depression meds, ≥1 med >1 daily use, control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: RxTimerCap; Assigned to Arm(s): All meds but depression, 1x daily use, RxTimerCap, All meds but depression, ≥1 med >1 daily use, RxTimerCap, Only depression meds, 1x daily use, RxTimerCap, Only depression meds, ≥1 med >1 daily use, RxTimerCap | Intervention Type: BEHAVIORAL; Name: Take-N-Slide; Assigned to Arm(s): All meds but depression, 1x daily use, Take-N-Slide, Only depression meds, 1x daily use, Take-N-Slide | Intervention Type: BEHAVIORAL; Name: Pillbox; Assigned to Arm(s): All meds but depression, 1x daily use, pillbox, All meds but depression, ≥1 med >1 daily use, pillbox, Only depression meds, 1x daily use, pillbox, Only depression meds, ≥1 med >1 daily use, pillbox
B: Arm Label: Placebo (pooled two times a day [BID]/three times a day [TID]); Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo two times a day (BID)/three times a day (TID) | Arm Label: AZLI (pooled two times a day [BID]/three times a day [TID]); Type: EXPERIMENTAL; Interventions: Drug: AZLI 75 mg two times a day (BID)/three times a day (TID) | Intervention Type: DRUG; Name: AZLI 75 mg two times a day (BID)/three times a day (TID); Assigned to Arm(s): AZLI (pooled two times a day [BID]/three times a day [TID]) | Intervention Type: DRUG; Name: Placebo two times a day (BID)/three times a day (TID); Assigned to Arm(s): Placebo (pooled two times a day [BID]/three times a day [TID])
C: Intervention Type: DRUG; Name: hypertonic saline; Assigned to Arm(s): N/A
D: Arm Label: Exercise Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise Intervention | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Exercise Intervention; Assigned to Arm(s): Exercise Intervention

Answer: C