Please select the eligibility criteria that correspond to the clinical trial below.
Title: Interactive Exoskeleton Robot for Walking - Ankle Joint
Brief Summary: A novel interactive exoskeleton robotic system with embedded force and motion sensors will be developed to facilitate walking of stroke patients with hemiparesis. The robot will synchronise with the gait pattern of the stroke patient to provide assistance in ankle dorsiflexion during swing phase. It is hypothesised that the robot can facilitate stable and longer walking distance for stroke patients with drop foot problem. It can be applied on unilateral side, which is suitable for stroke patients with hemiparesis. The whole system design is lightweight, compact, comfortable, and user-friendly in hospital or at home settings.


Options:
A: Inclusion Criteria:

* Elderly adults

  1. Age: between 65 and 84 years
  2. elderly adults who had no neurological or musculoskeletal abnormalities affecting gait
  3. Ability to walk at least 10m regardless of assist devices
  4. High levels of physical performance (SPPB \> 7)
  5. Subject is willing to be randomized to the control group or the treatment group
* Stroke

  1. Age: between 50 and 84 years
  2. ≥ 3 months post stroke
  3. Ability to walk at least 10m regardless of assist devices
  4. Adequate gait function (FAC \> 3)
  5. Physician approval for patient participation
  6. Subject is willing to be randomized to the control group or the treatment group

Exclusion Criteria:

* Elderly adults

  1. History of any diseases (eg. lower extremity orthopedic diseases, neurologic disorders, cardiovascular disease, heart failure, uncontrolled hypertension that affect walking capacity, efficiency, and endurance)
  2. Severe visual impairment or dizziness that increases the risk of falls
* Stroke

  1. Serious cardiac conditions (hospitalization for myocardial infarction or heart surgery within 3 months, history of congestive heart failure, documented serious and unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina or dyspnea at rest or during activities of daily living)
  2. Advanced liver, kidney, cardiac, or pulmonary disease
  3. History of concussion in last 6 months
  4. History of unexplained, recurring headaches, epilepsy/seizures/skull fractures or skull deficits
  5. Preexisting neurological disorders such as Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS), dementia
B: Inclusion Criteria:

* Patients with infratentorial stroke
* Cognitively intact enough to understand and follow the instructions from the investigator

Exclusion Criteria:

* chronic neurological pathology
* orthopedic injuries
* femur lengths of less than 34cm
* severely limited range of lower extremity joint motion
* medical instability
C: Inclusion Criteria:

* Have been admitted to a hospital unit for stroke treatment
* Stroke within last 3 months
* One-sided hemiparesis
* 19 years or older
* Requires 2-person assist to walk
* Able to communicate and follow instructions
* Prescribed to receive physiotherapy care

Exclusion Criteria:

* Stroke of non-vascular origin (e.g. tumour, infection)
* Significant musculoskeletal or other neurological condition
* Co-morbidities that would preclude activity
* Pregnant
* Unable to walk prior to stroke
* \<60 inches or \>74 inches in height
* \>220 pounds in weight
* Joint contractures or spasticity that would limit safe use of the Ekso exoskeleton
D: Inclusion Criteria:

1. Ischemic or hemorrphagic stroke with drop foot problem.
2. Sufficient cognition to follow simple instructions and to understand the content and purpose of the study. (Mini-Mental State Examination \> 21)
3. Capable of standing and walking independently for an extended period of time. (Functional Ambulation Category \> 3, Berg Balance Scale \> 40)

Exclusion Criteria:

1. Any medical or psychological dysfunctions that would affect their ability to comply with test study protocol, such as lower back pain, neuralgia, rotational vertigo, muscloskeletal disorders, injuries, and pregnancy.
2. Any severe contractures in hip, knee, or ankle joint that would preclude passive range of motion in the lower extremity.
3. Participation in any therapeutic treatment ("outside therapy") performed with the lower extremity during the planned study, including the baseline and the follow-up.

Answer: D