TrialPanorama/Dataset huggingface dataset:
Please select the eligibility criteria that correspond to the clinical trial below.
Title: A Phase 3 Randomized, Double-blind, Placebo-controlled Study in Older Subjects to Assess Safety and the Reversal of Rivaroxaban Anticoagulation With Intravenously Administered Andexanet Alpha
Brief Summary: The purpose of this study is to evaluate the ability of Andexanet Alfa to reverse the anticoagulation effect of Rivaroxaban.


Options:
A: Inclusion Criteria:

* age at least 18 years
* undergoing first ever multivessel CABG-only surgery with at least 2 free grafts (e.g. Radial artery, saphenous vein, free internal mammary artery)
* undergoing CABG with cardiopulmonary bypass

Exclusion Criteria:

* clear indication for anticoagulation (e.g. prosthetic heart valve replacement, recurrent DVT)
* allergy or intolerance of fondaparinux or unfractionated heparin
* renal failure or other contraindication for coronary artery graft CT angiogram
* inability to provide informed consent
B: Inclusion Criteria:

* Reasonably healthy men and women aged 50 to 75

Exclusion Criteria:

* History of abnormal bleeding, active bleeding or risk factors for bleeding
* History of thrombosis or risk factors for thrombosis
* History of adult asthma or use of inhaled medications
C: Inclusion Criteria:

* Patients with confirmed symptomatic Pulmonary Embolism (PE) or Deep Vein Thrombosis (DVT) who have been treated with acenocoumarol, warfarin or SR34006 for six months
* Written informed consent

Exclusion Criteria:

* Legal age limitations (country specific)
* Indication for anticoagulation other than PE or DVT
* Creatinine clearance (CLcr) \<10 mL/min, severe hepatic disease, or bacterial endocarditis
* Participation in a pharmacotherapeutic study other than the Van Gogh-PE or DVT study within the prior 30 days
* Life expectancy \<3 months
* Patients in whom anticoagulation treatment for their index PE or DVT should be continued beyond 6 months
* Active bleeding or high risk for bleeding
* Uncontrolled hypertension: systolic blood pressure \>180 mm Hg or diastolic blood pressure \> 110 mm Hg
* Pregnancy, or childbearing potential without proper contraceptive measures, women who are breastfeeding.
D: Inclusion Criteria:

* Reasonably healthy men and women aged 50 to 75

Exclusion Criteria:

* History of abnormal bleeding, active bleeding or risk factors for bleeding
* History of thrombosis or risk factors for thrombosis
* History of adult asthma or use of inhaled medications

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Movement System Impairment Based Classification Versus General Exercise for Chronic Non-specific Low Back Pain: a Randomised Controlled Trial
Brief Summary: The objective of this study is to investigate the efficacy of a treatment based on Movement System Impairment based classification (MSI) model in patients with chronic non-specific low back pain.


Options:
A: Inclusion Criteria:

* Subjects of both genders between 18 and 65 years of age with chronic non-specific LBP (pain for more than 3 months) with a pain intensity of at least 3 points measured by a 0-10 points pain numerical rating scale
* Subjects must be able to stand and walk independently
* Subjects must be able to read in Portuguese

Exclusion Criteria:

* Subjects with any contraindication to physical exercise according to the guidelines of the American College of Sports Medicine
* Subjects with severe depression (measured by depression, anxiety and stress scale - DASS)
* Subjects with serious spinal pathologies (fractures, tumors, and inflammatory pathologies such as ankylosing spondylitis), nerve root compromise (disc herniation and spondylolisthesis with neurological compromise, spinal stenosis, and others), serious cardiorespiratory diseases, previous back surgery or pregnancy.
* Subjects that cannot be classified into any of the five categories of the Movement System Impairment model upon initial assessment
B: Inclusion Criteria:

* low back pain for more than 3 months
* patients willing to participate and could participate in an exercise program safely and without cognitive impairments that would limit their participation.

Exclusion Criteria:

* past history of back surgery
* rheumatologic disorders
* spine infections
* spine exercise training in the 3 months before study onset.
C: Inclusion Criteria:

* Unspecific subacute, subacute remitting and chronic LBP
* Both sexes, 20-60 yrs of age
* LBP between 2-8 on a 11-pt numeric rating scale

Exclusion Criteria:

* Previous back surgery
* Sick listed more than one year
* Radiating pain below knee or motor deficits
* Systemic diseases and "red flags"
* Diagnosed psychiatric disease
* Ingoing insurance claim
* Pregnancy
D: Inclusion Criteria:

* Ages 18 - 35 years old (or emancipated minor)
* Participating in 91 W (combat medic) MOS training
* English speaking and reading

Exclusion Criteria:

* Currently seeking medical care for LBP
* Previous medical history that includes any surgery for LBP (examples include but are not limited to lumbar fusion, lumbar decompression, and lumbar discectomy)
* History of degenerative joint disease, arthritis, spine trauma or vertebral fractures, spondylolisthesis, and congenital spine disorders
* Currently unable to participate in AIT due to injury in foot, ankle, knee, hip, neck, shoulder, elbow, wrist, or hand injury.
* History of fracture (stress or traumatic) in proximal femur and/or pelvis
* Pregnancy (Note: Pregnancy will not result in termination from the study, even though it is an exclusion criteria at enrollment.)

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: A Cluster Randomized Trial to Evaluate the Increase in Usage of Evidence-based Practices for Stroke Treatment Using a Multifaceted Strategy
Brief Summary: Phase 1: An observational study ( registry) will be conducted with the objective of documenting the practice of stroke treatment in brazilian and latin american hospitals.

Phase 2: A cluster randomized trial aiming to evaluate the effect of a multifaceted strategy to increase evidence based treatments usage for stroke patients. The hospitals will be randomized into two groups: the multifaceted strategy group and the usual care group.


Options:
A: Patient Eligibility Criteria

Inclusion Criteria:

* Patients over 18 years old, diagnosed with ischemic stroke (including transient ischemic attack) with symptoms lasting up to 24 hours.

Exclusion Criteria:

* Patients with signs of hemorrhagic stroke, expansive lesions, central nervous system infections, and those coming from institutions that did not provide institutional approval form signed by the patients' guardians.

Cluster Eligibility Criteria

Inclusion Criteria:

* Hospitals with a emergency department, with available tomography, neurologist and alteplase

Exclusion Criteria:

* Hospitals that don't provide Institutional Authorization Form
B: Inclusion Criteria:

CHWs in districts with ICCM implementation

Exclusion Criteria:

CHWs in districts without ICCM implementation
C: Inclusion Criteria:

1. HIV-infected women (and their infants) who present to ANC or delivery with unknown HIV status;
2. HIV-infected women (and their infants) with previous history of ARV prophylaxis or treatment, but who are not on prophylaxis or treatment at the time of presentation for antenatal care or delivery.

Exclusion Criteria:

HIV-infected women with known status who are on ARV prophylaxis or treatment at the time of presentation to ANC.
D: Inclusion Criteria:

* all adult patients presenting for chronic or wellness care at the study practices

Exclusion Criteria:

* Acute illness

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Improving the Health of South African Women With Traumatic Stress in HIV Care
Brief Summary: In this study, the investigators propose to develop Improving AIDS Care after Trauma (ImpACT), an intervention based on theories of stress and coping and evidence-based treatment for traumatic stress. The intervention will target women in South Africa who have histories of sexual trauma and are newly initiating antiretroviral therapy (ART) in order to reduce avoidant coping and traumatic stress, improve care engagement, and reduce HIV risk behaviors.


Options:
A: Inclusion Criteria:

* 18 years of age or older
* Screens positive for IPV
* Literate in either English or Spanish

Exclusion Criteria:

* Less than 18 years of age
* pregnant at time of screening and consent
B: Inclusion Criteria:

* being victims of Intimate Partner Violence and seeking help at target clinics in order to reduce their psychological symptoms, currently living together with their partner/husband, meeting the set cut-off point on the PTSD scale according to DSM-IV.

Exclusion Criteria:

* schizophrenia, epilepsy, mental retardation, drug abuse and mal-nourishment
C: Inclusion Criteria:

* Exposed to a traumatic event at an adult age
* Primary PTSD diagnosis according to the DSM-5 criteria
* At least one PTSD related problem (depressive, anxiety or sleep disorders, pain, psychosocial stressors, inadequate social support, substance use disorder)
* Being fluent in French.

Exclusion Criteria:

* Schizophrenia diagnostic, current or past psychotic episodes, bipolar disorder, organic cerebral disorder or intellectual deficiency
* Presence of a trouble linked to a substance developed prior to the traumatic event
* Physical condition preventing participation in the study (e.g. cerebral trauma)
* Presence of active suicide ideas.
D: Inclusion Criteria:

* HIV infected women who are newly initiating ART at the study clinic
* History of sexual trauma
* Meets criteria for traumatic stress

Exclusion Criteria:

* Immediate suicide risk

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Effect of Including Fitness Testing in Preventive Health Checks on Cardiorespiratory Fitness and Motivation to Change Physical Activity Behaviour
Brief Summary: The purpose of this study is to investigate if including fitness testing in preventive health checks increase cardiorespiratory fitness and motivation to change physical activity behavior compared with preventive health checks without fitness testing.


Options:
A: Inclusion Criteria:

* men aged 65-74 years old living in the central region of Denmark

Exclusion Criteria:

* men not aged 65-74 years
* men aged 65-74 years old not living in the central region of Denmark
B: Inclusion Criteria:

* Citizens in the municipality of Randers per 01.01.2012
* Randomized for the fourth group of five groups in total to be invited for a preventive health check as part of the health promotion program, Check your health prevention program, conducted in the years 2012 to 2017.

Exclusion Criteria:

* Terminal illness as reported by the citizens general practitioner.
C: Inclusion Criteria:

Screening study: Every one aged 40-69 years (UK and DK) or 50-69 years(NL). Treatment study: All with screen detected type 2 diabetes.

Exclusion Criteria:

Participants are excluded if they already have diabetes at time of screening, are pregnant or lactating or have a severe psychotic illness, are house bound or have an illness with a likely survival of less than one year.
D: Inclusion Criteria:

* Citizens in the municipality of Randers per 01.01.2012
* Randomized for the third group of five to be invited for a preventive health check as part of the health promotion program, Check your health prevention program, conducted in the years 2012 to 2017.
* Having received a preventive health check before November 30 2015.
* Having consented for data to be used scientifically.

Exclusion Criteria:

* Terminal illness as reported by the citizens general practitioner.

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Early Childhood Practitioner's Knowledge and Attitudes Regarding Reporting Child Abuse/Neglect-iLookOut
Brief Summary: Phase 1 was a randomized control trial that used a test-retest model to evaluate the impact of iLook Out for Child Abuse, an online, interactive learning module about reporting suspected child abuse. Delivered via a learning management system to early childhood professionals who work with infants and young children, this study assessed iLookOut's effect on 1) knowledge about reporting suspected child abuse; 2) attitudes toward reporting suspected child abuse; and 3) preparedness to protect children at risk.

Findings from Phase 1 were that iLookOut will improved knowledge, changed attitudes, and increase self-reported preparedness of early childhood providers to report suspected child abuse.

Phase 2 of this trial is an open-enrollment study that records pre-/post- data on the same measurements as Phase 1, and is available for use (free of charge) for all childcare providers in Pennsylvania at https://www.ilookoutforchildabuse.com.


Options:
A: Inclusion Criteria:

* Working at the A\&E department of the UMC-Utrecht.

Exclusion Criteria:

* Absent during one of the two measurement periods.
B: Inclusion Criteria:

* Dental Interns enrolled in the Pediatric Dentistry and Dental Public Health Department, Faculty of Dentistry, Cairo University
* Participants of both genders
* Graduates of any dental school in Egypt

Exclusion Criteria:

* Participants who refused to sign the consent
* Participants who won't be able to have online access to the material
C: Inclusion Criteria:

* Paid or volunteer staff at childcare facility

Exclusion Criteria:

* Younger than 18 years of age
D: Inclusion Criteria:

* Works or volunteers at a childcare facility in Maine (i.e., home-based childcare, childcare center, Head Start facility, nursery school, pre-school)
* 18 years of age or older

Exclusion Criteria:

* Does not work or volunteer at a childcare facility in Maine
* Under 18 years of age

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Study of Management and Coaching in Atrial Fibrillation
Brief Summary: The purpose of this study is to evaluate the effect of a cognitive behavior therapy distress management program targeting wellbeing in patients with atrial fibrillation and their relatives.


Options:
A: Inclusion Criteria:

* Any condition indicated for cardiac rehabilitation: Acute coronary syndrome, percutaneous coronary intervention, coronary artery bypass graft +/- valve surgery or procedure (e.g., TAVI), heart transplant, ventricular assist device, heart failure, arrhythmia, rhythm device (i.e. implantable cardioverter-defibrillator, cardiac resynchronization therapy, pacemaker), congenital heart disease, minor non-disabling stroke or transient ischemic attack (i.e., can ambulate), peripheral vascular disease
* Proficiency in English language

Exclusion Criteria:

* Any musculoskeletal, neuromuscular, visual, cognitive or non-dysphoric psychiatric condition, or any serious or terminal illness not otherwise specified which would preclude CR eligibility based on CR guidelines
* Being discharged to long-term care
* Inability to ambulate (i.e. walk unaided at 2mph)
B: Inclusion Criteria:

* Patients diagnosed with atrial fibrillation.
* Relative to patient with atrial fibrillation.
* To be over 18 years old .

Exclusion Criteria:

* Unwillingness to participate in the study.
* Other complicating illness'.
* Language difficulties that prevent answering surveys.
* Participation in another study.
* Accommodation outside the hospital's catchment area.
C: Inclusion Criteria:

* All participants will have a diagnosis of CAD
* To be eligible they must be between the ages of 30-75 years of age-to ensure we are targeting those most likely to benefit from improving control to these medications
* Patients must have been prescribed a statin by their provider and a documented poor adherence as measured by a 16-month medication adherence rate (Medication Possession Ratio) of \<80%

Exclusion Criteria:

* Due to the use of the medication adherence reminder device, patients must speak English
* Have a home address
* Telephone number
* Be willing and able to identify a friend or family member
* The investigators will exclude atients with active substance abuse, significant hearing loss, or reduced cognitive ability as determined from the patient's problem list
D: Inclusion Criteria:

* Active diagnosis of ischemic heart disease in the year prior to inclusion in the study; have Internet at home or phone
* be able to follow the requirements of the study
* having signed informed consent for participation in the study.

Exclusion Criteria:

* low probability of cooperation in the study
* bystanders or displaced status
* institutionalized, with a terminal illness, physical or mental disability that prevents respond to questionnaires properly.

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Study of Management and Coaching in Atrial Fibrillation
Brief Summary: The purpose of this study is to evaluate the effect of a cognitive behavior therapy distress management program targeting wellbeing in patients with atrial fibrillation and their relatives.


Options:
A: Inclusion Criteria:

* The inclusion criteria included type 2 diabetes (as defined by the American Diabetes Association), a baseline glycosylated hemoglobin (HbA1c) value of 7-9%, and no previous exercise training in the past 6 months. All participants were free from diabetic nephropathy, diabetic retinopathy, severe diabetic neurophathy, severe cardiovascular and cerebrovascular diseases.

Exclusion Criteria:

* Participants were excluded if they dropped out or completed less than 80% of the training schedule.
B: Inclusion Criteria:

* Self-identifies as African American
* Resides in Washington, DC or surrounding communities
* Has stage I hypertension, defined as systolic blood pressure between 140 and 159 mm Hg and/or diastolic blood pressure between 90 and 99 mm Hg, on average, without taking antihypertensive medications in the sympatholytic class (e.g., beta blockers, alpha antagonists, central nervous system agonists)

Exclusion Criteria:

* Blood pressure levels of less than 140/90 mm Hg or greater than 160/100 mm Hg
* History of clinical cardiovascular disease (e.g., heart attack, angina, intermittent claudication, congestive heart failure, stroke)
* Long-term kidney failure
* Any other life-threatening illness (e.g., advanced cancer)
* History of major psychiatric disorder (e.g., psychosis, dementia, substance abuse disorder)
C: Inclusion Criteria:

1. Age 20 to 75 years
2. Hypertension by ABPM at baseline (daytime \> 135/85 mmHg or 24-hour ABPM \> 130/80 mmHg)

Exclusion Criteria:

1. Use of antihypertensive within 6 months of the screening ABPM.
2. Screening office BP \> 180/100 and ABPM \> 160/100 mmHg.
3. Diabetes
4. Secondary hypertension
5. Renal disease (GFR \< 60 ml/min or overt nephropathy)
6. History of heart attack
7. Stroke or TIA or
8. Re-vascularization procedure.
9. Active malignant disease (except non-melanoma skin cancer)
10. Epileptic seizure 6 months before the screening visit.
11. Congestive heart failure
12. Severe liver disease
13. Pregnancy or lactation period
14. Participation in a clinical trial or receipt of investigational compound or treatment in the 3 months prior to the initial screening visit.
15. Planned elective surgery during the study period except for cataract surgery
D: Inclusion Criteria:

* Patients diagnosed with atrial fibrillation.
* Relative to patient with atrial fibrillation.
* To be over 18 years old .

Exclusion Criteria:

* Unwillingness to participate in the study.
* Other complicating illness'.
* Language difficulties that prevent answering surveys.
* Participation in another study.
* Accommodation outside the hospital's catchment area.

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Alcohol, Suicide, and HIV Prevention for Teens in Mental Health Treatment
Brief Summary: This study examines whether an integrated alcohol/substance abuse, suicide, and HIV prevention protocol is associated with lower onset and frequency of alcohol and other drug use, suicidal behavior, and high risk sexual behavior among adolescents receiving community based mental health care.


Options:
A: Inclusion Criteria:

* ages 13-18
* English speaking adolescent and at least one English speaking parent
* receiving mental health treatment
* living with a parent or guardian willing to participate

Exclusion Criteria:

* Active Alcohol or Marijuana Dependence Diagnosis
* HIV infection
* Pregnant
* Current psychosis
* Cognitively unable to give assent
B: Inclusion Criteria:

* Aged 18 and over
* Have a history of self-harm
* Good verbal and written understanding of English

Exclusion Criteria:

* Aged under 18 years of age
* No history of self-harm
* Poor verbal and written understanding of English
* Not currently resident of an inpatient facility for mental illness
C: Inclusion Criteria:

* Suicide attempt or repetitive self-harm in the 3 months before study entry

Exclusion Criteria:

* Psychosis
* Substance dependency
* Immediate risk of out-of-home placement
* Symptoms/conditions that would interfere with assessment and/or intervention protocols
D: Inclusion Criteria:

* Informed Consent as documented by signature (Appendix Informed Consent Form)
* Age 18 or older
* Attempted suicide no longer than 6 months before inclusion
* Treatment in and outpatient clinic of the University Hospital of Psychiatry Zurich, a daycare clinic or on a ward of the University Hospital of Psychiatry Zurich
* Able and willing to comply with all study requirements, especially being able to participate and understand psychotherapy sessions

Exclusion Criteria:

* Acute psychosis with delusion and/or hallucination
* Dementia
* Insufficient ability to communicate in German language
* Chronic self-harming behaviour without a direct intention of suicide (Wolfersdorf \& Etzersdorfer, 2011)
* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant,
* Current electroconvulsive therapy (do to interference between cognitive side effects and psychotherapeutic intervention)
* Participation in another study with investigational drug within the 30 days preceding and during the present study,
* Previous enrolment into the current study,
* Enrolment of the investigator, his/her family members, employees and other dependent persons,

Answer: A