Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Comparative Effectiveness & Long Term Health Study in Wisconsin Smokers
Brief Summary: The overall purpose of this research is two-fold. First, the two smoking cessation medication treatments with the strongest evidence of effectiveness have never been directly compared. This research will determine how these two treatments compare in effectiveness in a head-to-head trial, and which types of smokers benefit most from each. Second, much of the data on smoking and health come from studies from many years ago. Today's smokers differ from earlier smokers in many ways that could influence the impact of smoking on health (e.g., weight, sex, diet, socio-economic status); the proposed work will determine how smoking cessation affects cardiovascular and pulmonary health in today's smokers.


Options:
A: Arm Label: Champix; Type: EXPERIMENTAL; Interventions: Drug: Champix | Arm Label: Long & Combination patch treatment; Type: EXPERIMENTAL; Interventions: Drug: Transdermal Nicoderm patch combined with gum or inhaler | Arm Label: Standard patch treatment; Type: EXPERIMENTAL; Interventions: Drug: Transdermal Nicoderm patch | Intervention Type: DRUG; Name: Champix; Assigned to Arm(s): Champix | Intervention Type: DRUG; Name: Transdermal Nicoderm patch combined with gum or inhaler; Assigned to Arm(s): Long & Combination patch treatment | Intervention Type: DRUG; Name: Transdermal Nicoderm patch; Assigned to Arm(s): Standard patch treatment
B: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Procedure: Dose adjustment of nicotine replacement therapies | Arm Label: 2; Type: OTHER; Interventions: Drug: nicotine patch | Intervention Type: PROCEDURE; Name: Dose adjustment of nicotine replacement therapies; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: nicotine patch; Assigned to Arm(s): 2
C: Arm Label: Gradual reduction; Type: EXPERIMENTAL; Interventions: Behavioral: Reduction Phone Counseling, Drug: Pre-Quit Nicotine Lozenges, Drug: Post-Quit Nicotine Lozenges | Arm Label: Abrupt cessation; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Abrupt Phone Counseling, Drug: Post-Quit Nicotine Lozenges | Arm Label: Minimal intervention; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Minimal Abrupt Phone Counseling, Drug: Post-Quit Nicotine Lozenges | Intervention Type: BEHAVIORAL; Name: Reduction Phone Counseling; Assigned to Arm(s): Gradual reduction | Intervention Type: BEHAVIORAL; Name: Abrupt Phone Counseling; Assigned to Arm(s): Abrupt cessation | Intervention Type: BEHAVIORAL; Name: Minimal Abrupt Phone Counseling; Assigned to Arm(s): Minimal intervention | Intervention Type: DRUG; Name: Pre-Quit Nicotine Lozenges; Assigned to Arm(s): Gradual reduction | Intervention Type: DRUG; Name: Post-Quit Nicotine Lozenges; Assigned to Arm(s): Abrupt cessation, Gradual reduction, Minimal intervention
D: Arm Label: Effectiveness of Nicotine patch only; Type: EXPERIMENTAL; Interventions: Drug: Nicotine Patch | Arm Label: Effectiveness of Combination NRT; Type: EXPERIMENTAL; Interventions: Drug: Nicotine lozenge, Drug: Nicotine Patch | Arm Label: Effectiveness of Varenicline [Chantix]; Type: EXPERIMENTAL; Interventions: Drug: Varenicline | Intervention Type: DRUG; Name: Varenicline; Assigned to Arm(s): Effectiveness of Varenicline [Chantix] | Intervention Type: DRUG; Name: Nicotine lozenge; Assigned to Arm(s): Effectiveness of Combination NRT | Intervention Type: DRUG; Name: Nicotine Patch; Assigned to Arm(s): Effectiveness of Combination NRT, Effectiveness of Nicotine patch only

Answer: D