Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase III Multicentre, Double Blind, Placebo-controlled, Parallel Group 52-week Study to Assess the Efficacy and Safety of 2 Dose Regimens of Lyophilised CDP870 as Additional Medication to Methotrexate in the Treatment of Signs and Symptoms and Preventing Structural Damage in Patients With Active Rheumatoid Arthritis Who Have an Incomplete Response to Methotrexate
Brief Summary: Patients will be assigned to one of three treatment groups. Study medication is administered over a 52 week study duration.


Options:
A: Arm Label: Arm 1; Type: PLACEBO_COMPARATOR; Interventions: Drug: BMS-945429 Placebo, Biological: BMS-945429, Drug: Methotrexate, Drug: Adalimumab Placebo | Arm Label: Arm 2; Type: EXPERIMENTAL; Interventions: Biological: BMS-945429, Drug: Methotrexate, Drug: Adalimumab Placebo | Arm Label: Arm 3; Type: EXPERIMENTAL; Interventions: Biological: BMS-945429, Drug: Methotrexate, Drug: Adalimumab Placebo | Arm Label: Arm 4; Type: EXPERIMENTAL; Interventions: Biological: BMS-945429, Drug: Methotrexate, Drug: Adalimumab Placebo | Arm Label: Arm 5; Type: EXPERIMENTAL; Interventions: Biological: BMS-945429, Drug: Methotrexate Placebo, Drug: Methotrexate, Drug: Adalimumab Placebo | Arm Label: Arm 6; Type: EXPERIMENTAL; Interventions: Biological: BMS-945429, Drug: Methotrexate Placebo, Drug: Methotrexate, Drug: Adalimumab Placebo | Arm Label: Arm 7; Type: ACTIVE_COMPARATOR; Interventions: Drug: Methotrexate, Drug: Adalimumab | Intervention Type: DRUG; Name: BMS-945429 Placebo; Assigned to Arm(s): Arm 1 | Intervention Type: BIOLOGICAL; Name: BMS-945429; Assigned to Arm(s): Arm 4 | Intervention Type: BIOLOGICAL; Name: BMS-945429; Assigned to Arm(s): Arm 3, Arm 6 | Intervention Type: BIOLOGICAL; Name: BMS-945429; Assigned to Arm(s): Arm 1, Arm 4 | Intervention Type: BIOLOGICAL; Name: BMS-945429; Assigned to Arm(s): Arm 2, Arm 5 | Intervention Type: DRUG; Name: Methotrexate; Assigned to Arm(s): Arm 1 | Intervention Type: DRUG; Name: Methotrexate; Assigned to Arm(s): Arm 2, Arm 3, Arm 4, Arm 7 | Intervention Type: DRUG; Name: Methotrexate Placebo; Assigned to Arm(s): Arm 5, Arm 6 | Intervention Type: DRUG; Name: Methotrexate; Assigned to Arm(s): Arm 5, Arm 6 | Intervention Type: DRUG; Name: Adalimumab Placebo; Assigned to Arm(s): Arm 1, Arm 2, Arm 3, Arm 4, Arm 5, Arm 6 | Intervention Type: DRUG; Name: Adalimumab; Assigned to Arm(s): Arm 7
B: Arm Label: Atacicept 150 mg with loading dose; Type: EXPERIMENTAL; Interventions: Drug: Atacicept: with loading dose | Arm Label: Atacicept 150 mg without loading dose; Type: EXPERIMENTAL; Interventions: Drug: Atacicept | Arm Label: Adalimumab; Type: ACTIVE_COMPARATOR; Interventions: Biological: Adalimumab | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo matched to atacicept | Intervention Type: DRUG; Name: Placebo matched to atacicept; Assigned to Arm(s): Placebo | Intervention Type: DRUG; Name: Atacicept: with loading dose; Assigned to Arm(s): Atacicept 150 mg with loading dose | Intervention Type: DRUG; Name: Atacicept; Assigned to Arm(s): Atacicept 150 mg without loading dose | Intervention Type: BIOLOGICAL; Name: Adalimumab; Assigned to Arm(s): Adalimumab
C: Arm Label: Golimumab (CNTO 148) with Methotrexate (MTX); Type: EXPERIMENTAL; Interventions: Drug: Golimumab, Drug: MTX | Arm Label: Infliximab with MTX; Type: EXPERIMENTAL; Interventions: Drug: MTX, Drug: Infliximab | Arm Label: Placebo with MTX; Type: PLACEBO_COMPARATOR; Interventions: Drug: MTX, Drug: Placebo | Intervention Type: DRUG; Name: Golimumab; Assigned to Arm(s): Golimumab (CNTO 148) with Methotrexate (MTX) | Intervention Type: DRUG; Name: MTX; Assigned to Arm(s): Golimumab (CNTO 148) with Methotrexate (MTX), Infliximab with MTX, Placebo with MTX | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo with MTX | Intervention Type: DRUG; Name: Infliximab; Assigned to Arm(s): Infliximab with MTX
D: Intervention Type: DRUG; Name: Certolizumab pegol (CDP870); Assigned to Arm(s): N/A

Answer: D