TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Prospective Study Comparing Brand and Generic Immunosuppression on Transplant Outcomes, Adherence, & Immune Response
Brief Summary: As the patents for brand-name immunosuppressive medications expire, there is increasing interest in using generic immunosuppressive drugs. However, despite pharmacokinetic studies showing bioequivalence, questions remain regarding the clinical impact of use of generic immunosuppression.

The most important immunosuppressive agent in the modern transplant era is arguably tacrolimus, a calcineurin-inhibitor with a narrow therapeutic index. This study seeks to answer the question regarding the clinical impact of generic tacrolimus use as measured primarily by acute rejection, loss of graft function, and patient death through a randomized trial of 2 phases: Brand tacrolimus only, and Generic A tacrolimus only. Given that kidney transplantations are the most commonly performed transplants with well-defined measures of rejection and graft failure, this organs will be studied in a six-center study designed to accrue the target number of transplant recipients within the one-year study period.

The study has now been branched off into 2 phases. Phase 1: consists of randomization of patients onto brand and generic tacrolimus. This was completed once 40 brand patients were enrolled. Phase 2: consists of patients being enrolled only on generic tacrolimus (standard of care from subject's insurance). This will be completed once there is a total of 160 generic participants. 200 participants total in the study.


Options:
A: Arm Label: Tacrolimus BID; Type: ACTIVE_COMPARATOR; Interventions: Drug: Tacrolimus BID | Arm Label: Advagraf QD; Type: ACTIVE_COMPARATOR; Interventions: Drug: Advagraf QD | Intervention Type: DRUG; Name: Tacrolimus BID; Assigned to Arm(s): Tacrolimus BID | Intervention Type: DRUG; Name: Advagraf QD; Assigned to Arm(s): Advagraf QD
B: Arm Label: Intervention Group; Type: EXPERIMENTAL; Interventions: Behavioral: Behavioral Contract | Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Behavioral Contract; Assigned to Arm(s): Intervention Group
C: Arm Label: Brand Tacrolimus Only : Prograf; Type: OTHER; Interventions: Drug: Prograf | Arm Label: Generic A Only; Type: OTHER; Interventions: Drug: Tacrolimus | Intervention Type: DRUG; Name: Prograf; Assigned to Arm(s): Brand Tacrolimus Only : Prograf | Intervention Type: DRUG; Name: Tacrolimus; Assigned to Arm(s): Generic A Only
D: Arm Label: Medication Dosage Reminders; Type: EXPERIMENTAL; Interventions: Device: Vitality GlowCaps | Arm Label: Medicaiton Dosage Reminders + Coordinator Support; Type: EXPERIMENTAL; Interventions: Device: Vitality GlowCaps | Arm Label: Usual Care with GlowCap; Type: OTHER; Interventions: Device: Vitality GlowCaps | Intervention Type: DEVICE; Name: Vitality GlowCaps; Assigned to Arm(s): Medicaiton Dosage Reminders + Coordinator Support, Medication Dosage Reminders, Usual Care with GlowCap

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effectiveness of an Intervention for Improving Drug Prescription in Primary Care Patients With Multimorbidity and Polypharmacy: Study Protocol of a Cluster Randomized Clinical Trial (Multi-PAP Project)
Brief Summary: This study assesses the effectiveness of a complex intervention in young-old patients with multimorbidity and polypharmacy aimed at improving physician drug prescription in primary care, measured by means of the Medication Appropriateness Index (MAI)-score at six 6 (T1) and 12 (T2) months from baseline compared to usual care.


Options:
A: Arm Label: Multi-PAP intervention; Type: EXPERIMENTAL; Interventions: Other: Multi-PAP, Other: Usual care | Arm Label: Usual care; Type: ACTIVE_COMPARATOR; Interventions: Other: Usual care | Intervention Type: OTHER; Name: Multi-PAP; Assigned to Arm(s): Multi-PAP intervention | Intervention Type: OTHER; Name: Usual care; Assigned to Arm(s): Multi-PAP intervention, Usual care
B: Intervention Type: PROCEDURE; Name: Therapeutic education; Assigned to Arm(s): N/A
C: Arm Label: Medication therapy management; Type: EXPERIMENTAL; Interventions: Other: Medication therapy management | Intervention Type: OTHER; Name: Medication therapy management; Assigned to Arm(s): Medication therapy management
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Health Literacy-Focused High Blood Pressure Intervention | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Health Literacy-Focused High Blood Pressure Intervention | Intervention Type: BEHAVIORAL; Name: Health Literacy-Focused High Blood Pressure Intervention; Assigned to Arm(s): 1, 2

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effectiveness of an Intervention for Improving Drug Prescription in Primary Care Patients With Multimorbidity and Polypharmacy: Study Protocol of a Cluster Randomized Clinical Trial (Multi-PAP Project)
Brief Summary: This study assesses the effectiveness of a complex intervention in young-old patients with multimorbidity and polypharmacy aimed at improving physician drug prescription in primary care, measured by means of the Medication Appropriateness Index (MAI)-score at six 6 (T1) and 12 (T2) months from baseline compared to usual care.


Options:
A: Arm Label: Multi-PAP intervention; Type: EXPERIMENTAL; Interventions: Other: Multi-PAP, Other: Usual care | Arm Label: Usual care; Type: ACTIVE_COMPARATOR; Interventions: Other: Usual care | Intervention Type: OTHER; Name: Multi-PAP; Assigned to Arm(s): Multi-PAP intervention | Intervention Type: OTHER; Name: Usual care; Assigned to Arm(s): Multi-PAP intervention, Usual care
B: Arm Label: Multidisciplinary medication review; Type: EXPERIMENTAL; Interventions: Procedure: Multidisciplinary medication review | Arm Label: usual care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: PROCEDURE; Name: Multidisciplinary medication review; Assigned to Arm(s): Multidisciplinary medication review
C: Arm Label: I; Type: EXPERIMENTAL; Interventions: Other: Drug review 80+ -To reduce usage of hospital care | Arm Label: C; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Drug review 80+ -To reduce usage of hospital care; Assigned to Arm(s): I
D: Intervention Type: BEHAVIORAL; Name: Comprehensive pharmacy care program; Assigned to Arm(s): N/A

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effectiveness of an Intervention for Improving Drug Prescription in Primary Care Patients With Multimorbidity and Polypharmacy: Study Protocol of a Cluster Randomized Clinical Trial (Multi-PAP Project)
Brief Summary: This study assesses the effectiveness of a complex intervention in young-old patients with multimorbidity and polypharmacy aimed at improving physician drug prescription in primary care, measured by means of the Medication Appropriateness Index (MAI)-score at six 6 (T1) and 12 (T2) months from baseline compared to usual care.


Options:
A: Arm Label: Optimization of drug prescribing; Type: EXPERIMENTAL; Interventions: Other: Optimization of drug prescribing | Arm Label: No intervention; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Optimization of drug prescribing; Assigned to Arm(s): Optimization of drug prescribing
B: Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Intervention arm; Type: EXPERIMENTAL; Interventions: Other: Optimization strategy (complex intervention) | Intervention Type: OTHER; Name: Optimization strategy (complex intervention); Assigned to Arm(s): Intervention arm
C: Arm Label: Multi-PAP intervention; Type: EXPERIMENTAL; Interventions: Other: Multi-PAP, Other: Usual care | Arm Label: Usual care; Type: ACTIVE_COMPARATOR; Interventions: Other: Usual care | Intervention Type: OTHER; Name: Multi-PAP; Assigned to Arm(s): Multi-PAP intervention | Intervention Type: OTHER; Name: Usual care; Assigned to Arm(s): Multi-PAP intervention, Usual care
D: Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Other: Deprescribing opportunities | Intervention Type: OTHER; Name: Deprescribing opportunities; Assigned to Arm(s): Intervention

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Treatment of Intracerebral Hemorrhage in Patients on Non-vitamin K Antagonist Oral Anticoagulants (NOAC) With Tranexamic Acid
Brief Summary: Novel, non-vitamin K antagonist oral anticoagulants (NOAC) target selected players in the coagulation cascade as the direct thrombin inhibitor dabigatran and the factor Xa-inhibitors apixaban and rivaroxaban. Intracerebral hemorrhage (ICH) is the most feared complication of NOAC treatment (NOAC-ICH).

Outcome of NOAC-ICH can be devastating and is a major cause of death and disability. There is no proven treatment for NOAC-ICH. Hematoma expansion (HE) is associated with unfavorable outcome. Tranexamic acid (TA) is an anti-fibrinolytic drug that is used in a number of bleeding conditions other than ICH.


Options:
A: Arm Label: Tranexamic Acid; Type: ACTIVE_COMPARATOR; Interventions: Drug: Tranexamic Acid | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Tranexamic Acid; Assigned to Arm(s): Tranexamic Acid | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
B: Arm Label: Prothrombin complex concentrate (PCC); Type: EXPERIMENTAL; Interventions: Drug: Prothrombin complex concentrate (PCC); fresh frozen plasma (FFP) | Arm Label: Fresh frozen plasma (FFP); Type: EXPERIMENTAL; Interventions: Drug: Prothrombin complex concentrate (PCC); fresh frozen plasma (FFP) | Intervention Type: DRUG; Name: Prothrombin complex concentrate (PCC); fresh frozen plasma (FFP); Assigned to Arm(s): Fresh frozen plasma (FFP), Prothrombin complex concentrate (PCC)
C: Arm Label: Group 1-Recombinant activated factor VII; Type: ACTIVE_COMPARATOR; Interventions: Drug: recombinant activated factor VII | Arm Label: Group 2 - Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Arm Label: Group 3 - Observation Only Arm; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: recombinant activated factor VII; Assigned to Arm(s): Group 1-Recombinant activated factor VII | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Group 2 - Placebo
D: Arm Label: Tranexamic acid; Type: EXPERIMENTAL; Interventions: Drug: Tranexamic acid | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Saline 0.9% | Intervention Type: DRUG; Name: Tranexamic acid; Assigned to Arm(s): Tranexamic acid | Intervention Type: DRUG; Name: Saline 0.9%; Assigned to Arm(s): Placebo

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Long-acting Naltrexone for Pre-release Prisoners: A Randomized Trial of Mobile Treatment
Brief Summary: This proposed five-year study will focus on whether the addition of providing XR-NTX treatment at a patients' place of residence will increase adherence and thus efficacy of the medication.Following initial screening, informed consent, and medical examination, pre-release prisoners at each facility will be block randomized (N=240) within gender to either: Condition 1. XR-NTX-OTx (n=120): One injection of XR-NTX in prison, followed by six monthly injections post-release in the community at an opioid treatment program; or Condition 2. XR-NTX+MMTx (n=120): One injection of XR-NTX in prison, followed by six monthly injections post-release in the community at the patient's place of residence.


Options:
A: Arm Label: Extended-Release Naltrexone; Type: ACTIVE_COMPARATOR; Interventions: Drug: Extended-Release Naltrexone | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Extended-Release Naltrexone | Intervention Type: DRUG; Name: Extended-Release Naltrexone; Assigned to Arm(s): Extended-Release Naltrexone, Placebo
B: Arm Label: Interim; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Interim | Arm Label: Comprehensive; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Comprehensive | Arm Label: Restored; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Restored | Intervention Type: BEHAVIORAL; Name: Interim; Assigned to Arm(s): Interim | Intervention Type: BEHAVIORAL; Name: Comprehensive; Assigned to Arm(s): Comprehensive | Intervention Type: BEHAVIORAL; Name: Restored; Assigned to Arm(s): Restored
C: Arm Label: Extended-release naltrexone (XR-NTX); Type: ACTIVE_COMPARATOR; Interventions: Drug: Extended-Release Naltrexone | Arm Label: Motivational Enhancement Counseling Only; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Motivational Enhancement Counseling | Intervention Type: DRUG; Name: Extended-Release Naltrexone; Assigned to Arm(s): Extended-release naltrexone (XR-NTX) | Intervention Type: BEHAVIORAL; Name: Motivational Enhancement Counseling; Assigned to Arm(s): Motivational Enhancement Counseling Only
D: Arm Label: Vivitrol at place of residence; Type: EXPERIMENTAL; Interventions: Drug: XR-NTX, Other: place of residence | Arm Label: Vivitrol at opioid treatment program; Type: ACTIVE_COMPARATOR; Interventions: Drug: XR-NTX, Other: opioid treatment program | Intervention Type: DRUG; Name: XR-NTX; Assigned to Arm(s): Vivitrol at opioid treatment program, Vivitrol at place of residence | Intervention Type: OTHER; Name: place of residence; Assigned to Arm(s): Vivitrol at place of residence | Intervention Type: OTHER; Name: opioid treatment program; Assigned to Arm(s): Vivitrol at opioid treatment program

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Enhancement of Presence, Compassion and Resilience Bringing the Practice of Mindfulness Into Nature - Preventing Mental Fatigue in Healthcare Professionals.
Brief Summary: The purpose of the study is to determine whether a five day mindfulness retreat in nature can increase measures of attention and self-compassion, and reduce stress among bachelor students at Danish Universities and University Colleges. Secondary whether the expression of inflammatory markers can be reduced .

It is the hypothesis that perceived stress is reduced and the expression of genetic markers of inflammation is reduced after a five day mindfulness retreat.


Options:
A: Intervention Type: BEHAVIORAL; Name: Problem-Solving Skills Training; Assigned to Arm(s): N/A
B: Arm Label: Mindfulness in nature; Type: EXPERIMENTAL; Interventions: Behavioral: Mindfulness | Arm Label: Mindfulness indoor; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Mindfulness | Arm Label: Wait list control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Mindfulness; Assigned to Arm(s): Mindfulness in nature, Mindfulness indoor
C: Arm Label: Mobile Video Counseling; Type: EXPERIMENTAL; Interventions: Behavioral: Stress management counseling | Arm Label: Offline Counseling; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Stress management counseling | Arm Label: Selfcare; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Stress management counseling; Assigned to Arm(s): Mobile Video Counseling, Offline Counseling
D: Arm Label: ACT; Type: EXPERIMENTAL; Interventions: Other: Acceptance and Commitment Therapy (ACT) | Arm Label: WPI; Type: EXPERIMENTAL; Interventions: Other: workplace intervention (WPI) | Arm Label: ACT and WPI; Type: EXPERIMENTAL; Interventions: Other: Acceptance and Commitment Therapy (ACT), Other: workplace intervention (WPI) | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Acceptance and Commitment Therapy (ACT); Assigned to Arm(s): ACT, ACT and WPI | Intervention Type: OTHER; Name: workplace intervention (WPI); Assigned to Arm(s): ACT and WPI, WPI

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Enhancement of Presence, Compassion and Resilience Bringing the Practice of Mindfulness Into Nature - Preventing Mental Fatigue in Healthcare Professionals.
Brief Summary: The purpose of the study is to determine whether a five day mindfulness retreat in nature can increase measures of attention and self-compassion, and reduce stress among bachelor students at Danish Universities and University Colleges. Secondary whether the expression of inflammatory markers can be reduced .

It is the hypothesis that perceived stress is reduced and the expression of genetic markers of inflammation is reduced after a five day mindfulness retreat.


Options:
A: Arm Label: Mindfulness in nature; Type: EXPERIMENTAL; Interventions: Behavioral: Mindfulness | Arm Label: Mindfulness indoor; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Mindfulness | Arm Label: Wait list control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Mindfulness; Assigned to Arm(s): Mindfulness in nature, Mindfulness indoor
B: Arm Label: Face-to-face group-based mindfulness; Type: EXPERIMENTAL; Interventions: Behavioral: Face-to-face group-based mindfulness | Arm Label: Internet-based mindfulness; Type: EXPERIMENTAL; Interventions: Behavioral: Internet-based mindfulness | Arm Label: Waiting-list control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Face-to-face group-based mindfulness; Assigned to Arm(s): Face-to-face group-based mindfulness | Intervention Type: BEHAVIORAL; Name: Internet-based mindfulness; Assigned to Arm(s): Internet-based mindfulness
C: Arm Label: Mental Training for Surgeons; Type: EXPERIMENTAL; Interventions: Behavioral: Mindfulness Based Stress Reduction - modified | Arm Label: The Mind of a Surgeon; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Active listening and reading | Intervention Type: BEHAVIORAL; Name: Mindfulness Based Stress Reduction - modified; Assigned to Arm(s): Mental Training for Surgeons | Intervention Type: BEHAVIORAL; Name: Active listening and reading; Assigned to Arm(s): The Mind of a Surgeon
D: Arm Label: Experimental; Type: EXPERIMENTAL; Interventions: Behavioral: Smartphone-delivered Intervention (SmartQuit) | Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: : Smartphone-delivered Intervention (Standard of care app) | Intervention Type: BEHAVIORAL; Name: Smartphone-delivered Intervention (SmartQuit); Assigned to Arm(s): Experimental | Intervention Type: BEHAVIORAL; Name: : Smartphone-delivered Intervention (Standard of care app); Assigned to Arm(s): Control

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Self-Monitoring Assessment in Real Time: 2-SMART
Brief Summary: The purpose of the study is to test the effectiveness of two different methods of mobile dietary self-monitoring for weight loss. Both of these interventions will provide weight loss information through twice weekly audio podcasts. In addition to the podcasts, participants will be asked to track their diet using an assigned mobile applications (for their smartphone), which will be randomly assigned.


Options:
A: Arm Label: Sequential Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: self-monitoring of body weight, Behavioral: self-monitoring of diet, Behavioral: weekly personalized feedback + lessons + action plans | Arm Label: Simultaneous Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: self-monitoring of body weight, Behavioral: self-monitoring of diet, Behavioral: weekly personalized feedback + lessons + action plans | Arm Label: Control (diet-tracking only); Type: EXPERIMENTAL; Interventions: Behavioral: self-monitoring of diet | Intervention Type: BEHAVIORAL; Name: self-monitoring of body weight; Assigned to Arm(s): Sequential Intervention, Simultaneous Intervention | Intervention Type: BEHAVIORAL; Name: self-monitoring of diet; Assigned to Arm(s): Control (diet-tracking only), Sequential Intervention, Simultaneous Intervention | Intervention Type: BEHAVIORAL; Name: weekly personalized feedback + lessons + action plans; Assigned to Arm(s): Sequential Intervention, Simultaneous Intervention
B: Arm Label: fitbit ultra; Type: EXPERIMENTAL; Interventions: Behavioral: fitbit Ultra | Arm Label: Pedometer; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Pedometer | Intervention Type: BEHAVIORAL; Name: fitbit Ultra; Assigned to Arm(s): fitbit ultra | Intervention Type: BEHAVIORAL; Name: Pedometer; Assigned to Arm(s): Pedometer
C: Arm Label: Photo App; Type: EXPERIMENTAL; Interventions: Behavioral: Photo App, Behavioral: Podcasts | Arm Label: Diet App; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Diet App, Behavioral: Podcasts | Intervention Type: BEHAVIORAL; Name: Photo App; Assigned to Arm(s): Photo App | Intervention Type: BEHAVIORAL; Name: Diet App; Assigned to Arm(s): Diet App | Intervention Type: BEHAVIORAL; Name: Podcasts; Assigned to Arm(s): Diet App, Photo App
D: Arm Label: Online dietician lifestyle counseling; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Online dietetic lifestyle counseling | Arm Label: Usual care; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Usual care | Intervention Type: BEHAVIORAL; Name: Online dietetic lifestyle counseling; Assigned to Arm(s): Online dietician lifestyle counseling | Intervention Type: BEHAVIORAL; Name: Usual care; Assigned to Arm(s): Usual care

Answer: C