Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase III Trial Evaluating The Role Of Exemestane Plus GnRH Analogue As Adjuvant Therapy For Premenopausal Women With Endocrine Responsive Breast Cancer
Brief Summary: RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using triptorelin, exemestane, and tamoxifen may fight breast cancer by blocking the use of estrogen. It is not yet known whether giving triptorelin together with exemestane is more effective than triptorelin and tamoxifen in treating hormone-responsive breast cancer.

PURPOSE: This randomized phase III trial is studying triptorelin and exemestane to see how well they work compared to triptorelin and tamoxifen in treating premenopausal women with hormone-responsive breast cancer.


Options:
A: Arm Label: T+OFS; Type: ACTIVE_COMPARATOR; Interventions: Drug: tamoxifen, Drug: triptorelin | Arm Label: E+OFS; Type: EXPERIMENTAL; Interventions: Drug: exemestane, Drug: triptorelin | Intervention Type: DRUG; Name: exemestane; Assigned to Arm(s): E+OFS | Intervention Type: DRUG; Name: tamoxifen; Assigned to Arm(s): T+OFS | Intervention Type: DRUG; Name: triptorelin; Assigned to Arm(s): E+OFS, T+OFS
B: Arm Label: TAM+OFS(E) group; Type: EXPERIMENTAL; Interventions: Drug: goserelin, Drug: tamoxifen | Arm Label: TAM(D) group; Type: ACTIVE_COMPARATOR; Interventions: Drug: tamoxifen | Arm Label: Permanent postmenopausal(A) group; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: TAM(B); Type: ACTIVE_COMPARATOR; Interventions: Drug: tamoxifen | Arm Label: TAM+OFS (C); Type: EXPERIMENTAL; Interventions: Drug: goserelin, Drug: tamoxifen | Intervention Type: DRUG; Name: goserelin; Assigned to Arm(s): TAM+OFS (C), TAM+OFS(E) group | Intervention Type: DRUG; Name: tamoxifen; Assigned to Arm(s): TAM(B), TAM(D) group, TAM+OFS (C), TAM+OFS(E) group
C: Arm Label: Switch to Zoladex + AI for 3-2 years; Type: EXPERIMENTAL; Interventions: Drug: Zoladex+AI | Arm Label: TAM; Type: EXPERIMENTAL; Interventions: Drug: TAM | Intervention Type: DRUG; Name: Zoladex+AI; Assigned to Arm(s): Switch to Zoladex + AI for 3-2 years | Intervention Type: DRUG; Name: TAM; Assigned to Arm(s): TAM
D: Arm Label: Tamoxifen; Type: ACTIVE_COMPARATOR; Interventions: Other: Laboratory Biomarker Analysis, Other: Quality-of-Life Assessment, Drug: Tamoxifen | Arm Label: T+OFS; Type: EXPERIMENTAL; Interventions: Other: Laboratory Biomarker Analysis, Procedure: Oophorectomy, Other: Quality-of-Life Assessment, Radiation: Radiation Therapy, Drug: Tamoxifen, Drug: Triptorelin | Arm Label: E+OFS; Type: EXPERIMENTAL; Interventions: Drug: Exemestane, Other: Laboratory Biomarker Analysis, Procedure: Oophorectomy, Other: Quality-of-Life Assessment, Radiation: Radiation Therapy, Drug: Triptorelin | Intervention Type: DRUG; Name: Exemestane; Assigned to Arm(s): E+OFS | Intervention Type: OTHER; Name: Laboratory Biomarker Analysis; Assigned to Arm(s): E+OFS, T+OFS, Tamoxifen | Intervention Type: PROCEDURE; Name: Oophorectomy; Assigned to Arm(s): E+OFS, T+OFS | Intervention Type: OTHER; Name: Quality-of-Life Assessment; Assigned to Arm(s): E+OFS, T+OFS, Tamoxifen | Intervention Type: RADIATION; Name: Radiation Therapy; Assigned to Arm(s): E+OFS, T+OFS | Intervention Type: DRUG; Name: Tamoxifen; Assigned to Arm(s): T+OFS, Tamoxifen | Intervention Type: DRUG; Name: Triptorelin; Assigned to Arm(s): E+OFS, T+OFS

Answer: A