TrialPanorama/Dataset huggingface dataset:
Please select the outcome measures that correspond to the clinical trial below.
Title: Treatment of Uterine Myoma With 2.5 or 5 mg Mifepristone Daily During 3 Months With 9 Months Post-treatment Follow-up. Randomized Clinical Trial.
Brief Summary: Objectives: to evaluate the efficacy, safety and quality of life by using 2.5 and mifepristone 5 mg daily doses to treat uterine fibroids over 3 months with a 9 months follow-up period.

The hypothesis of the study is that the 2.5 mg dosage resulted in a lesser reduction in fibroid size but a similar improvement in quality of life when compared to the 5 mg dose.


Options:
A: Volume of the uterine leiomyomata with 2,5mg vs 5 mg daily of mifepristone after 3 months of treatment (3 months)
B: Percentage of Subjects With Reduction of Uterine Bleeding at Week 13 Visit Defined as Pictorial Blood-loss Assessment Chart (PBAC) Score < 75 at End-of-treatment Visit (Week 13 Visit) (3 months); Co-primary Safety Endpoint: Serum Estradiol Levels at End of Treatment Visit (Week 13 Visit) for PGL4001 Compared With GnRHagonist (Week 13 visit); Co-primary Safety Endpoint: % of Subjects Reporting Moderate or Severe Hot Flushes as Adverse Events Throughout the Treatment Period for PGL4001 Compared With GnRH-agonist (Up to week 17)
C: Myoma size (2004 to 2007)
D: percentage of subjects in amennorrhoea at the end of each PGL4001 treatment course received (From baseline to end of each PGL4001 treatment (3months treatment))

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Do Elastic Abdominal Binders Reduce Post Operative Pain and Blood Loss?
Brief Summary: This is a pilot study investigating the use of abdominal binders after cesarean sections. The researchers are testing whether elastic abdominal binders improve postoperative pain control and reduce postoperative blood loss. Blood loss and pain control are both concerns after giving birth. It is hoped that the use of an abdominal binder after giving birth will provide a non-pharmacologic way to to reduce blood loss and manage pain.


Options:
A: Lowest Pain Level Postoperative (24 hours postoperative); Average Pain Level Postoperative (24 hours postoperative); Worst Pain Level Postoperative (24 hours postoperative)
B: Pain, assessed by patients using a pain scale (72 hours or hospital stay)
C: Pain score by visual analogue scale (VAS) on movement at 48 hours postoperatively (48 hours)
D: Pain measurement (up to post operateive day 2); Patient Distress score (up to post operateive day 2)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Serious Illness Communication Project
Brief Summary: The purpose of the study is to evaluate the impact of implementing a "Serious Illness Conversation Guide" to guide patient/family-clinician discussions and planning about end-of-life care decisions. The goal of the intervention is to improve achievement of patient care priorities and peacefulness at the end of life for patients with serious and life-threatening illness and their families. We hypothesize that patients whose physician is trained to use and adheres to the elements of the Serious Illness Conversation Guide will demonstrate enhanced consistency between documented key priorities and care received, and will experience greater peace in the final month of life; similarly, their families will experience higher satisfaction with care.


Options:
A: Receipt of colorectal cancer screening exam (fecal occult blood test, flexible sigmoidoscopy, or colonoscopy) within 4 months following delivery of an electronic message within the personal health record
B: Enhanced goal-consistent care (up to 2 years); PEACE (up to 2 years)
C: N/A
D: Rate of appropriate thromboprophylaxis (During hospital stay (expected average duration of 1 week))

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Serious Illness Communication Project
Brief Summary: The purpose of the study is to evaluate the impact of implementing a "Serious Illness Conversation Guide" to guide patient/family-clinician discussions and planning about end-of-life care decisions. The goal of the intervention is to improve achievement of patient care priorities and peacefulness at the end of life for patients with serious and life-threatening illness and their families. We hypothesize that patients whose physician is trained to use and adheres to the elements of the Serious Illness Conversation Guide will demonstrate enhanced consistency between documented key priorities and care received, and will experience greater peace in the final month of life; similarly, their families will experience higher satisfaction with care.


Options:
A: preferences for CPR (within one hour after oncology visit)
B: Hospital Anxiety and Depression Scale (At 6 months)
C: Enhanced goal-consistent care (up to 2 years); PEACE (up to 2 years)
D: family decision-making self-efficacy (at 8 weeks after the intervention)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Serious Illness Communication Project
Brief Summary: The purpose of the study is to evaluate the impact of implementing a "Serious Illness Conversation Guide" to guide patient/family-clinician discussions and planning about end-of-life care decisions. The goal of the intervention is to improve achievement of patient care priorities and peacefulness at the end of life for patients with serious and life-threatening illness and their families. We hypothesize that patients whose physician is trained to use and adheres to the elements of the Serious Illness Conversation Guide will demonstrate enhanced consistency between documented key priorities and care received, and will experience greater peace in the final month of life; similarly, their families will experience higher satisfaction with care.


Options:
A: PROMIS Physical Functioning (6 months); PROMIS Satisfaction With Social Roles (6 months); PROMIS Anxiety (6 months); PROMIS Depression (6 months); PROMIS Fatigue (6 months)
B: Mean Patient-centered Communication in Advanced Cancer Score (3 years)
C: Enhanced goal-consistent care (up to 2 years); PEACE (up to 2 years)
D: Patient and family ratings on the "End-of-Life domain" of the Quality of Communication Questionaire (QOC) (4/1/2007-3/31/2012)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Serious Illness Communication Project
Brief Summary: The purpose of the study is to evaluate the impact of implementing a "Serious Illness Conversation Guide" to guide patient/family-clinician discussions and planning about end-of-life care decisions. The goal of the intervention is to improve achievement of patient care priorities and peacefulness at the end of life for patients with serious and life-threatening illness and their families. We hypothesize that patients whose physician is trained to use and adheres to the elements of the Serious Illness Conversation Guide will demonstrate enhanced consistency between documented key priorities and care received, and will experience greater peace in the final month of life; similarly, their families will experience higher satisfaction with care.


Options:
A: The primary effect outcome measurement is the number and type of referred patients with psychosocial problems to psychosocial caregivers and type of referrals with respect to psychosocial problems. (Is measured at three (T3) and twelve (T4) months after first measurement)
B: Enhanced goal-consistent care (up to 2 years); PEACE (up to 2 years)
C: To investigate whether the use of QOL questionnaires during the assessment and management of lung cancer patients results in improved quality of life
D: Subscale quality of life of the questionnaire: EORTC QLQ C30 (After each treatment completion, during follow up; first year every 3 months, second year every 6 months)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Impact of Resistance Training During Hospitalization in COPD Patients: a Randomized and Controlled Trial
Brief Summary: The purpose of this study is to determine whether resistance exercise are effective in combating the decline in muscle strength during an exacerbation of Chronic Obstructive Pulmonary Disease (COPD).


Options:
A: Changes from baseline in the St. George's Respiratory Questionnaire for COPD patients (SGRQ-C) total score at week 6 and 12 (Week 0, 6 and 12)
B: Daily number of steps (changes from baseline to 3 months)
C: The benefits of resistance training during exacerbation of COPD on peripheral muscle strength during hospitalization (Will be evaluated on the second day of hospitalization, the day of hospital discharge (this time interval must be longer than five days))
D: 6-Minute Walking Distance (Baseline and 8 weeks follow-up)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Impact of Resistance Training During Hospitalization in COPD Patients: a Randomized and Controlled Trial
Brief Summary: The purpose of this study is to determine whether resistance exercise are effective in combating the decline in muscle strength during an exacerbation of Chronic Obstructive Pulmonary Disease (COPD).


Options:
A: The benefits of resistance training during exacerbation of COPD on peripheral muscle strength during hospitalization (Will be evaluated on the second day of hospitalization, the day of hospital discharge (this time interval must be longer than five days))
B: Reduction in the decline of muscle force during the exacerbation. (discharge Day 9)
C: Non-outpatient COPD related hospital attendance (A+E attendance, inpatient admission or death) (3-months)
D: To determine the impact of the intervention initiated after hospital discharge from a COPD exacerbation on the rate of COPD related re-hospitalizations in the intervention versus the control group . (12 months); To determine the impact of the intervention initiated after hospital discharge from a COPD exacerbation on the rate of the composite outcome, COPD related hospitalizations or death in the intervention versus the control group. (12 months)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: DETermination of the Role of OXygen in Suspected Acute Myocardial Infarction (DETO2X-AMI) Based on the SWEDEHEART Registry
Brief Summary: The use of supplemental oxygen in the setting of suspected acute myocardial infarction (AMI) is manifested in international treatment guidelines and established in prehospital and hospital clinical routine throughout the world.

However, to date there is no conclusive evidence from adequately designed and powered trials supporting this practice. Existing data is conflicting and failing to clarify the role of supplemental oxygen in AMI.

The DETO2X-AMI trial is designed to shed light on this important issue.


Options:
A: 90-days mortality (90 days)
B: 1-year all-cause mortality (1 year)
C: oxygen saturation ≥90% (baseline)
D: Death (Day 28)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: DETermination of the Role of OXygen in Suspected Acute Myocardial Infarction (DETO2X-AMI) Based on the SWEDEHEART Registry
Brief Summary: The use of supplemental oxygen in the setting of suspected acute myocardial infarction (AMI) is manifested in international treatment guidelines and established in prehospital and hospital clinical routine throughout the world.

However, to date there is no conclusive evidence from adequately designed and powered trials supporting this practice. Existing data is conflicting and failing to clarify the role of supplemental oxygen in AMI.

The DETO2X-AMI trial is designed to shed light on this important issue.


Options:
A: N/A
B: Surgical wound infection (14 days after surgery)
C: Mortality in ICU (30 days)
D: 1-year all-cause mortality (1 year)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: DETermination of the Role of OXygen in Suspected Acute Myocardial Infarction (DETO2X-AMI) Based on the SWEDEHEART Registry
Brief Summary: The use of supplemental oxygen in the setting of suspected acute myocardial infarction (AMI) is manifested in international treatment guidelines and established in prehospital and hospital clinical routine throughout the world.

However, to date there is no conclusive evidence from adequately designed and powered trials supporting this practice. Existing data is conflicting and failing to clarify the role of supplemental oxygen in AMI.

The DETO2X-AMI trial is designed to shed light on this important issue.


Options:
A: A single SPECT scan will be used to determine whether or not the treatment results in a significant reduction in infarct size in the treatment group. The scan is performed 14 days post-event. (14 +/- 7 days); Safety will be determined by comparing 30-day MACE (Major Adverse Cardiac Events) rates, where MACE is comprised by the combined incidence of death, stroke, repeat MI, and target vessel revascularization. (30 days)
B: Myocardial Infarct Size (At 72 hours post infarct)
C: 1-year all-cause mortality (1 year)
D: Chest pain measured with VAS (1 h)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Efficacy of Conservative Versus Surgical Therapy for Carpal Tunnel Syndrome: a Randomised Clinical Trial
Brief Summary: It is a randomized clinical trial comparing surgical and conservative (physical therapy) treatments for women with carpal tunnel syndrome (CTS). The purpose of the study is to determine the efficacy of physical therapy versus endoscopic surgery in pain and disability in women with carpal tunnel syndrome at medium and long-term follow-up periods. We hypothesized that proper physical therapy approach can be equally effective than surgical intervention for improving pain and function in patients with carpal tunnel syndrome.


Options:
A: Carpal Tunnel Syndrome Assessment Questionnaire- function scale (12 months)
B: Percentage of Participants Achieving Sustained Remission Rate At Week 104 (Week 104)
C: Changes in the intensity of pain symptoms between baseline and follow-up periods (Baseline and 1, 3, 6 and 12 months after the intervention)
D: Number of Patients Who Have Had Carpal Tunnel Release Surgery on the Study Hand (5 to 7 years); Symptom Severity Score (5-7 years)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Contingency Management for Smoking Cessation in Homeless Smokers
Brief Summary: The purpose of this study is to examine the effectiveness of an internet-based contingency management program for smoking cessation in persons who are homeless. Thirty homeless smokers will be enrolled in the study. Participants will receive payment based on their own low carbon monoxide readings, which indicate being quit from smoking. Participants will be prescribed nicotine replacement (patches and either gum or lozenge)and bupropion. All participants will receive a four sessions of smoking cessation counseling, and will be trained to perform carbon monoxide monitoring with a device provided by the study. They will also be provided with a mobile phone equipped with a video camera, and will use this equipment at home to monitor their carbon monoxide . Participants will record videos of themselves taking a carbon monoxide reading and displaying the results, and will upload the videos to a secured website that is only accessible by the research team members and the participant. Payment will be based on providing carbon monoxide readings that indicate abstinence.

The study is designed to address the following aims:

Specific Aim 1: To evaluate whether it is feasible to use internet-based contingency management for helping smokers who are homeless stop smoking.

Specific Aim 2: To evaluate how effective internet-based contingency managementis on decreasing smoking in smokers who are homeless.


Options:
A: 90 day continuous abstinence (90 days); 7 day abstinence (7 days)
B: A Serious Quit Attempt in Which the Participant Intends to Permanently Stop Smoking (From study enrollment through six month follow-up); A 24 Hour Serious Quit Attempt in Which the Participant Intends to Permanently Stop Smoking (From study enrollment through six month follow-up)
C: Quit Attempt(s) (Any time within 26 weeks)
D: Breath carbon monoxide (Throughout study - one year)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: A Randomized Study Evaluating the Role of Ultra-sound Guidance When Drawing Radial Arterial Blood Samples
Brief Summary: Previous studies have demonstrated that an experienced ultrasound operator is able to efficiently perform radial arterial puncture on patients where an initial operator failed to puncture arteries via simple palpation.

The objective of this study is to compare "difficult-to-puncture" patients randomized into two groups: one group where ultrasound is used to aid artery localisation, and one group where only palpation is used.


Options:
A: Time Needed to Correctly Insert the Arterial or Midline Catheter. (Immediately following intervention (within 2 hours))
B: Is only one puncture attempt necessary to attain the radial artery? yes/no (maximum two hours)
C: Quick Disabilities of the Arm Shoulder and Hand (DASH) Questionnaire Score (0-100) (1 year); Thumb and Forefinger Pinch Strength Test (1 year); Hand Grip Strength Test (1 month)
D: Only one attempt at arterial puncture was necessary (yes/no) (Day 0 - end of procedure)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: A Randomized Study Evaluating the Role of Ultra-sound Guidance When Drawing Radial Arterial Blood Samples
Brief Summary: Previous studies have demonstrated that an experienced ultrasound operator is able to efficiently perform radial arterial puncture on patients where an initial operator failed to puncture arteries via simple palpation.

The objective of this study is to compare "difficult-to-puncture" patients randomized into two groups: one group where ultrasound is used to aid artery localisation, and one group where only palpation is used.


Options:
A: Arterial catheterization time (Interval between contact of the ultrasound transducer with the skin and confirmation of an arterial waveform on the monitor, an expected average of 200 seconds)
B: Time Needed to Correctly Insert the Arterial or Midline Catheter. (Immediately following intervention (within 2 hours))
C: Only one attempt at arterial puncture was necessary (yes/no) (Day 0 - end of procedure)
D: Duration of Use of Arterial Cannula (During Procedure)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: A Randomized Study Evaluating the Role of Ultra-sound Guidance When Drawing Radial Arterial Blood Samples
Brief Summary: Previous studies have demonstrated that an experienced ultrasound operator is able to efficiently perform radial arterial puncture on patients where an initial operator failed to puncture arteries via simple palpation.

The objective of this study is to compare "difficult-to-puncture" patients randomized into two groups: one group where ultrasound is used to aid artery localisation, and one group where only palpation is used.


Options:
A: Only one attempt at arterial puncture was necessary (yes/no) (Day 0 - end of procedure)
B: Is only one puncture attempt necessary to attain the radial artery? yes/no (maximum two hours)
C: Arterial catheterization time (Interval between contact of the ultrasound transducer with the skin and confirmation of an arterial waveform on the monitor, an expected average of 200 seconds)
D: Number of Attempts (Immediately during procedure. (up to 30 minutes))

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Improving the Delivery of Intensive Gait Training in the Clinical Setting to Augment Community Ambulation
Brief Summary: The purpose of this study is to demonstrate the efficacy of intensive locomotor interventions early post stroke. An intensive locomotor training (LT) program will be compared to an active control, conventional physical therapy. It is proposed that an early and intensive stepping paradigm that is not typically employed early in physical therapy will lead to superior outcomes and improved community mobility. A randomized, blinded, controlled trial will test subjects with moderate to severe locomotor dysfunction in individuals post-stroke to compare walking-related outcomes after intensive gait training (including treadmill, overground, stair training, and skilled walking training) to outcomes after conventional physical therapy.


Options:
A: Fugl-Meyer Assessment (upper extremity subscale) (0-, 4- week)
B: Ambulatory function measured by the Six Minute Walk Test (Rehabilitation discharge (average 4-5 weeks post admission))
C: Change in 10 meter walk test (Pre Test, 4 weeks, 8 weeks, 3 month follow up)
D: Box and Block Test; Data Collected = Number of Blocks Moved (Baseline/pretest; posttest given between days 17-22 (posttest days 3 -8)); Fugl-Meyer Upper Extremity Motor Test (Baseline/pretest; posttest given between days 17-22 (posttest days 3 -8)); Fractionated Reaction Time (Baseline/pretest; posttest given between days 17-22 (posttest days 3-8))

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Improving the Delivery of Intensive Gait Training in the Clinical Setting to Augment Community Ambulation
Brief Summary: The purpose of this study is to demonstrate the efficacy of intensive locomotor interventions early post stroke. An intensive locomotor training (LT) program will be compared to an active control, conventional physical therapy. It is proposed that an early and intensive stepping paradigm that is not typically employed early in physical therapy will lead to superior outcomes and improved community mobility. A randomized, blinded, controlled trial will test subjects with moderate to severe locomotor dysfunction in individuals post-stroke to compare walking-related outcomes after intensive gait training (including treadmill, overground, stair training, and skilled walking training) to outcomes after conventional physical therapy.


Options:
A: modified Rankin Score (3 months)
B: Change in 10 meter walk test (Pre Test, 4 weeks, 8 weeks, 3 month follow up)
C: Change from baseline in Cognitive Function at 3 months (Baseline, Month 3); Change from baseline in Functional Performance at 3 months (Baseline, Month 3); Change from baseline in Muscle Function at 3 months (Baseline, Month 3)
D: Change in the Reintegration to Normal Living Index (RNL) from baseline (baseline, 12 weeks, 24 weeks)

Answer: B