Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: N/A
Brief Summary: This study will examine the effect of a culturally-safe two-way supportive text message intervention to reduce HIV vulnerability among young Indigenous people who use illicit drugs in a community-based setting.

The study is nested within The Cedar Project, an ongoing cohort study addressing HIV and Hepatitis C vulnerability among young Indigenous people who use drugs in Vancouver and Prince George, British Columbia, Canada. Indigenous collaborators and investigators, collectively known as the Cedar Project Partnership, govern the entire research process.

A stratified Zelen pre-randomized design will be used to identify a random selection of cohort members to be offered the Cedar Project mHealth intervention with consent. Participants in the intervention arm will receive a package of supports, including a mobile phone and long-distance plan, weekly two-way supportive text messaging via the WelTel platform, and support from Cedar Advocates. Those drawn from the cohort study population as the comparison group will continue on in the usual Cedar Project study under its existing informed consent with no change whatsoever to their participation in the overall study.

The main outcome is an HIV propensity score, assessed at six months and one year. Secondary outcomes include HIV risk, resilience, access to drug-related services, psychological distress, and connection to culture measured at six months and one year. Primary analysis is by intention to treat.


Options:
A: Arm Label: Fixed SMS, real-time monitoring; Type: EXPERIMENTAL; Interventions: Device: Fixed SMS, real-time monitoring | Arm Label: Triggered SMS, real-time monitoring; Type: EXPERIMENTAL; Interventions: Device: Triggered SMS, real-time monitoring | Arm Label: control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: Fixed SMS, real-time monitoring; Assigned to Arm(s): Fixed SMS, real-time monitoring | Intervention Type: DEVICE; Name: Triggered SMS, real-time monitoring; Assigned to Arm(s): Triggered SMS, real-time monitoring
B: Arm Label: Motivational SMS; Type: EXPERIMENTAL; Interventions: Behavioral: Motivational SMS | Arm Label: Travel Voucher; Type: EXPERIMENTAL; Interventions: Behavioral: Motivational SMS, Behavioral: Travel Voucher | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Motivational SMS; Assigned to Arm(s): Motivational SMS, Travel Voucher | Intervention Type: BEHAVIORAL; Name: Travel Voucher; Assigned to Arm(s): Travel Voucher
C: Arm Label: The Cedar Project mHealth Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: The Cedar Project mHealth intervention | Arm Label: Comparison group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: The Cedar Project mHealth intervention; Assigned to Arm(s): The Cedar Project mHealth Intervention
D: Arm Label: SmartMoms-Clinic; Type: EXPERIMENTAL; Interventions: Behavioral: SmartMoms | Arm Label: SmartMoms-Phone; Type: EXPERIMENTAL; Interventions: Behavioral: SmartMoms | Arm Label: Physician Directed; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: SmartMoms; Assigned to Arm(s): SmartMoms-Clinic, SmartMoms-Phone

Answer: C