Please select the eligibility criteria that correspond to the clinical trial below.
Title: Family Management of Childhood Diabetes Study
Brief Summary: This is a multi-center, randomized controlled trial to test whether a clinic-integrated, low intensity, multi-component behavioral intervention is effective in preventing the deterioration in glycemic control, treatment adherence, and quality of life that commonly occur during late childhood and early adolescence in youth with type 1 diabetes. The study will also examine mechanisms and processes that influence the effectiveness of family management of diabetes during this developmental period.


Options:
A: Inclusion Criteria:

* type 1 diabetes with duration at least 12 months
* between ages 12-16 years at registration
* poor glycemic control (A1c 8.0-13.0%)
* parent/guardian willing to also participate
* not planning on moving in the following 18 months

Exclusion Criteria:

* pregnant (if female)
* diabetes type 2 or gestational
* Pre-existing systemic chronic disease (drug abuse, cancer, certain psychiatric conditions)
B: Inclusion Criteria:

* Moderate to severe TBI that occurred within the last 24 months
* Overnight hospital stay
* English-speaking
* Parent must be willing to provide informed consent

Exclusion Criteria:

* Child does not live with parents or guardian
* Child or parent has history of hospitalization for psychiatric problem
* Child suffered a non-blunt injury (e.g., projectile wound, stroke, drowning, or other form of asphyxiation)
* Diagnosed with moderate or severe mental retardation, autism, or a significant developmental disability
C: Child Inclusion Criteria:

* Age 9.0 to \<14.5.
* Type 1 diabetes diagnosis (diagnosed by ADA criteria) for a minimum of 1 year for the main subgroup or 3 months for the recent onset subgroup.
* Insulin dose greater than or equal to 0.5 u/kg/day for the main subgroup or 0.2 u/kg/day for the recent onset subgroup; with 2 or more daily injections or use of insulin pump.
* Most recent A1c is \>6.0% and \<13.0%; \<12.0% for those diagnosed for less than 1 year.
* Willing to provide informed assent.

Parent/Family Environment Inclusion Criteria

* Child lives in geographically stable home, no multiple foster homes, boarding school, or institutions expected in next 2 years.
* The same 1 or 2 adult caregivers have accompanied the child to every diabetes clinic visit in the past year, and at least 1 caregiver agrees to participate in all aspects of the protocol (single-parent families, blended families, and separated parents will be eligible).
* Home has telephone access.
* Child had at least 2 clinic visits within last 12 months.
* Parent and child willing to come to clinic every 3 months for duration (2 years) of study.
* If a family has more than one eligible child, all qualifying children who provide consent/assent will participate in assessment and intervention or control activities; however, only the oldest qualifying child will be included in statistical analyses.

Child Exclusion Criteria:

* Presence of a major chronic diseases (except well-controlled thyroid, asthma, celiac).
* Presence of a major visual/auditory impairments.
* Child is in a self-contained special education class throughout the school day.
* Record of inpatient hospitalization for mental disorder in past six months including substance abuse rehabilitation, eating disorder units or day treatment programs. Current diagnosis of eating disorder. History of anti-psychotic medications for the past 6 months.
* Diagnosis of mental retardation.
* Unable to read and write English at 2nd grade level.
* Children who are currently enrolled in any intervention study are not eligible for enrollment. Those who have been in an intervention arm of a trial of a behavioral, psychological or psychoeducational intervention and concluded their study follow-up within the past 12 months are also ineligible to participate. However, children who were in a standard care control group in an intervention study are eligible once they have completed all scheduled study follow-ups. Children cannot enroll in another intervention study during the course of this study. Enrollment of children who are currently participating in another observational study will be at the discretion of the site principal investigator.

Parent/Family Environment Exclusion Criteria

* Family has plans to re-locate out of area within the next 2 years of the study.
* Participating caretaker is currently undergoing treatment for substance abuse.
* Participating caretaker has been hospitalized in past 6 months for mental disorder.
* Participating caretaker has history of psychosis.
* Families who are currently enrolled in any intervention study are not eligible for enrollment. Those who have been in an intervention arm of a trial of a behavioral, psychological or psychoeducational intervention and concluded their study follow-up within the past 12 months are also ineligible to participate. However, families who were in a standard care control group in an intervention study are eligible once they have completed all scheduled study follow-ups. Families cannot enroll in another intervention study during the course of this study. Enrollment of families who are currently participating in another observational study will be at the discretion of the site principal investigator.

The family must reside within 90 miles (one-way) of the clinic (main or satellite), or agree to meet at a mutually agreed upon closer location for conduct of the home assessment.
D: Inclusion Criteria:

* Physician diagnosis of asthma for at least a year
* At least one acute exacerbation of asthma in past 12 months that required a visit to the emergency department, hospitalization or an unscheduled office visit for acute care and/or a course of oral steroids.
* Taking daily controller medications or symptoms consistent with persistent asthma

Exclusion Criteria:

* No phone
* Unable to speak English
* Child has another disease that requires regular monitoring by pediatrician
* A sibling is already enrolled in the study
* Child's primary asthma provider is an asthma specialist

Answer: C