Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Field Efficacy Of Insecticide Treated Uniforms And Skin Repellents To Reduce Malaria Incidence In Military Personnel On Active Duty In Regions Of Hyperendemicity
Brief Summary: Purpose

While there is strong evidence that permethrin treated clothing prevents insect bites there is insufficient evidence from trials to demonstrate a reduction in infections. The evidence that topical insect repellants prevent malaria is more robust, but studies in civilian suffer from poor compliance. It is not known if there is an added benefit from combining the two. The effectiveness of permethrin-treated uniforms with and without DEET lotion are compared in a 2x2 design in Mgambo Jeshi la Kujenga Taifa (JKT) military camp in Tanga region.

The four arms are: 1) combined intervention group receiving permethrin treated uniform (PTU) and 30% DEET (diethyl toluamide) liposome formula; 2) permethrin intervention group receiving PTU and placebo lotion; 3) DEET intervention group receiving untreated army combat uniform (ACU) and 30% DEET liposome formula; 4) placebo group receiving untreated ACU and placebo lotion. Both participants and investigators will be blinded to treatment allocation.

The outcome measure is the incidence of Plasmodium falciparum malaria infection measured by Polymerase Chain Reaction every month by active case detection.


Options:
A: Arm Label: Topical Repellent & LLIN; Type: EXPERIMENTAL; Interventions: Other: Mosquito topical repellent | Arm Label: Long Lasting Insecticidal Nets; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Mosquito topical repellent; Assigned to Arm(s): Topical Repellent & LLIN
B: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo lotion, Other: Army combat uniform | Arm Label: Combo; Type: ACTIVE_COMPARATOR; Interventions: Other: Ultra 30 Insect Repellent Lotion (30% Lipo DEET), Other: Permethrin Factory-Treated Army Combat Uniforms | Arm Label: Permethrin; Type: ACTIVE_COMPARATOR; Interventions: Other: Permethrin Factory-Treated Army Combat Uniforms, Other: Placebo lotion | Arm Label: DEET; Type: ACTIVE_COMPARATOR; Interventions: Other: Ultra 30 Insect Repellent Lotion (30% Lipo DEET), Other: Army combat uniform | Intervention Type: OTHER; Name: Ultra 30 Insect Repellent Lotion (30% Lipo DEET); Assigned to Arm(s): Combo, DEET | Intervention Type: OTHER; Name: Permethrin Factory-Treated Army Combat Uniforms; Assigned to Arm(s): Combo, Permethrin | Intervention Type: OTHER; Name: Placebo lotion; Assigned to Arm(s): Permethrin, Placebo | Intervention Type: OTHER; Name: Army combat uniform; Assigned to Arm(s): DEET, Placebo
C: Arm Label: 20% deet insect repellent; Type: EXPERIMENTAL; Interventions: Drug: 20% deet insect repellent | Arm Label: lotion without repellent active; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo control | Intervention Type: DRUG; Name: 20% deet insect repellent; Assigned to Arm(s): 20% deet insect repellent | Intervention Type: DRUG; Name: placebo control; Assigned to Arm(s): lotion without repellent active
D: Arm Label: Personal protection package; Type: EXPERIMENTAL; Interventions: Combination Product: Personal protection package | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: COMBINATION_PRODUCT; Name: Personal protection package; Assigned to Arm(s): Personal protection package

Answer: B