Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Randomized Controlled Trial of the Impact of Treating Moderately Malnourished Women in Pregnancy
Brief Summary: Malnutrition during pregnancy is more common in poor women in the developing world due to inadequate dietary intake combined with increased nutrient requirements; pregnancy risk is more consequential than among other demographic groups with increased risk of maternal and infant mortality and the lifelong effects of fetal malnutrition. The benefits of treating moderate malnutrition during pregnancy remain largely undocumented. This study tests the hypothesis that providing either a fortified flour or fortified paste-based supplementary food designed to replete the nutrient deficits during pregnancy will result in improved maternal nutritional recovery rates and higher infant birth weights and lengths. This study is a randomized, controlled clinical trial of 3 supplementary foods in 1800 moderately malnourished Malawian women who are pregnant. Subjects will receive one of 3 food rations: 1) a ready-to-use supplementary food formulated to deliver about 200% of the recommended daily allowance (RDA) of most micronutrients in pregnancy (RUSF-P), 2) corn soy blend with a multiple micronutrient tablet chosen to deliver about 200% of the RDA of most micronutrients (CSB-P) or 3), the standard of care which is a corn soy blend with supplementary iron and folic acid (CSB), delivering between 0-350% of the RDA. Subjects will receive the supplementary food until they recover from MAM. The outcome of the pregnancy and maternal nutritional status will be followed until 3 months after delivery.


Options:
A: Intervention Type: DRUG; Name: Aspirin; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Folate; Assigned to Arm(s): N/A
B: Arm Label: Zinc-fortified bread (10 mg zinc/d); Type: EXPERIMENTAL; Interventions: Dietary Supplement: Zinc-fortified bread, Dietary Supplement: Placebo supplement | Arm Label: Zinc fortified bread (20 mg zinc/d); Type: EXPERIMENTAL; Interventions: Dietary Supplement: Zinc-fortified bread, Dietary Supplement: Placebo supplement | Arm Label: Zinc supplemented group; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Zinc supplement, Dietary Supplement: Non-fortified bread | Arm Label: Non-fortified group; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Non-fortified bread, Dietary Supplement: Placebo supplement | Intervention Type: DIETARY_SUPPLEMENT; Name: Zinc-fortified bread; Assigned to Arm(s): Zinc fortified bread (20 mg zinc/d), Zinc-fortified bread (10 mg zinc/d) | Intervention Type: DIETARY_SUPPLEMENT; Name: Zinc supplement; Assigned to Arm(s): Zinc supplemented group | Intervention Type: DIETARY_SUPPLEMENT; Name: Non-fortified bread; Assigned to Arm(s): Non-fortified group, Zinc supplemented group | Intervention Type: DIETARY_SUPPLEMENT; Name: Placebo supplement; Assigned to Arm(s): Non-fortified group, Zinc fortified bread (20 mg zinc/d), Zinc-fortified bread (10 mg zinc/d)
C: Arm Label: corn-soy-blend; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: corn-soy blend, Dietary Supplement: iron, Dietary Supplement: folic acid | Arm Label: corn-soy-blend + multiple micronutrients; Type: EXPERIMENTAL; Interventions: Dietary Supplement: corn-soy blend, Dietary Supplement: UNIMMAP | Arm Label: ready-to-use supplementary food; Type: EXPERIMENTAL; Interventions: Dietary Supplement: ready-to-use supplementary food | Intervention Type: DIETARY_SUPPLEMENT; Name: ready-to-use supplementary food; Assigned to Arm(s): ready-to-use supplementary food | Intervention Type: DIETARY_SUPPLEMENT; Name: corn-soy blend; Assigned to Arm(s): corn-soy-blend, corn-soy-blend + multiple micronutrients | Intervention Type: DIETARY_SUPPLEMENT; Name: iron; Assigned to Arm(s): corn-soy-blend | Intervention Type: DIETARY_SUPPLEMENT; Name: folic acid; Assigned to Arm(s): corn-soy-blend | Intervention Type: DIETARY_SUPPLEMENT; Name: UNIMMAP; Assigned to Arm(s): corn-soy-blend + multiple micronutrients
D: Arm Label: Dietary supplement; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Corn Soya Blend+ | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DIETARY_SUPPLEMENT; Name: Corn Soya Blend+; Assigned to Arm(s): Dietary supplement

Answer: C