Please select the eligibility criteria that correspond to the clinical trial below.
Title: Psychosocial Research to Improve Drug Treatment in Pregnancy (PRIDE-P)
Brief Summary: The purpose of this study is... To assess whether a behavioral treatment that combines motivational enhancement and cognitive skills training therapy (MET-CBT) is more effective than brief advice in: 1) decreasing use of a full range of psychoactive substances (e.g. marijuana, cocaine, methamphetamines, alcohol, nicotine, opioids) in pregnant substance using and dependent women; 2) decreasing HIV risk behavior; 3) improving birth outcomes (longer gestations and greater birth weight).


Options:
A: Main Study:

Inclusion Criteria:

* adolescents ages 12 to 17
* used any illicit drugs (other than alcohol and tobacco) in the 30-day period
* live with or intend to live with a formal or informal family

Exclusion Criteria:

* suicidal or homicidal ideation.

Follow Up Study:

Inclusion Criteria:

* youth must have signed consent during the main study to be approached for future research
* currently 18 years old or older
B: Inclusion Criteria:

* Individuals diagnosed with one or more substance use disorders (alcohol, cannabis, and or stimulant abuse/dependence) and an independent co-occurring depressive disorder (major depression or dysthymia) will be included.

Exclusion Criteria:

* Individuals with substance induced mood disorders and individuals experiencing persistent psychotic symptoms.
* Those with life threatening or unstable medical illness, neurological disorders, or inability to read will be excluded.
* Individuals currently prescribed steroids, disulfiram, or long acting benzodiazepines will be excluded.
C: Inclusion Criteria:

* Ages 18 to 65 years
* Must be able to give informed consent
* Must live in the area for the next 3 months
* Depression subscale of the Hospital Anxiety and Depression Scale, HADS-D score ≥ 8
* Fagerstrom score \> 3
* Must be sedentary, have not participated regularly in aerobic physical exercise (for at least 20 minutes per day, 3 days per week) for the past six months.
* Must be able to exercise at 60% maximum heart rate (MHR) (cleared by a physician)

Exclusion Criteria:

* Cannot read or write fluently in the French language
* Pregnancy or plans to attempt pregnancy
* 60 minutes or more per week of moderate or vigorous physical activity
* Currently in a quit smoking program
* Currently using NRT of any kind or using any other quit smoking method or treatment
* Poor willingness or inability to comply with protocol requirements

Medical problems:

* Cancer treatment within the past 6 monthsPsychiatric Problems
* Currently suicidal or psychotic, (or suicidal/psychotic in last 6 months)
* Taking these specific medications for psychiatric problems: Mood stabilizer (Lithium, Depakote, Neurontin), Antipsychotics (Haldol, Clozaril, Risperdal)
* Currently diagnosis of a bipolar disorder as assessed by MINI 5.0
* Currently diagnosis of a alcohol dependence as assessed by MINI 5.0
D: Inclusion Criteria:

Pregnant women, age 16 or older, alcohol or illicit drug use in the past 30 days -

Exclusion Criteria:

Nonfluent in English or Spanish, pending incarceration, psychotic, cognitively unable to give informed consent, actively suicidal or homicidal, already engaged in addictions treatment, primarily addicted to nicotine or heroin.

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Answer: D