Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A 26-week, Randomized, Double Blind, Parallel-group Multicenter Study to Assess the Efficacy and Safety of QVA149 (110/50 μg o.d.) vs Tiotropium (18 µg o.d.) + Salmeterol/Fluticasone Propionate FDC (50/500 µg b.i.d.) in Patients With Moderate to Severe COPD
Brief Summary: This study will evaluate the efficacy and safety of QVA149 (110/50 μg o.d.) vs tiotropium (18 µg o.d.) + salmeterol/fluticasone propionate FDC (50/500 µg b.i.d.) in patients with moderate to severe COPD


Options:
A: Arm Label: BGF (PT010) MDI 320/14.4/9.6 μg; Type: EXPERIMENTAL; Interventions: Drug: BGF MDI 320/14.4/9.6 μg | Arm Label: BGF (PT010) MDI 160/14.4/9.6 μg; Type: EXPERIMENTAL; Interventions: Drug: BGF MDI 160/14.4/9.6 μg | Arm Label: BFF (PT009) MDI 320/9.6 μg; Type: EXPERIMENTAL; Interventions: Drug: BFF MDI 320/9.6 μg | Arm Label: GFF (PT003) MDI 14.4/9.6 μg; Type: EXPERIMENTAL; Interventions: Drug: GFF MDI 14.4/9.6 μg | Intervention Type: DRUG; Name: BGF MDI 320/14.4/9.6 μg; Assigned to Arm(s): BGF (PT010) MDI 320/14.4/9.6 μg | Intervention Type: DRUG; Name: GFF MDI 14.4/9.6 μg; Assigned to Arm(s): GFF (PT003) MDI 14.4/9.6 μg | Intervention Type: DRUG; Name: BGF MDI 160/14.4/9.6 μg; Assigned to Arm(s): BGF (PT010) MDI 160/14.4/9.6 μg | Intervention Type: DRUG; Name: BFF MDI 320/9.6 μg; Assigned to Arm(s): BFF (PT009) MDI 320/9.6 μg
B: Arm Label: BGF MDI (PT010) 320/14.4/9.6 μg ex-actuator; Type: EXPERIMENTAL; Interventions: Drug: BGF MDI 320/14.4/9.6 μg | Arm Label: GFF MDI (PT003) 14.4/9.6 μg ex-actuator; Type: EXPERIMENTAL; Interventions: Drug: GFF MDI (PT003) 14.4/9.6 μg | Arm Label: BFF MDI (PT009) 320/9.6 μg ex-actuator; Type: EXPERIMENTAL; Interventions: Drug: BFF MDI (PT009) 320/9.6 μg | Arm Label: Symbicort; Type: ACTIVE_COMPARATOR; Interventions: Drug: Symbicort® Turbuhaler® (TBH) Inhalation Powder | Intervention Type: DRUG; Name: BGF MDI 320/14.4/9.6 μg; Assigned to Arm(s): BGF MDI (PT010) 320/14.4/9.6 μg ex-actuator | Intervention Type: DRUG; Name: GFF MDI (PT003) 14.4/9.6 μg; Assigned to Arm(s): GFF MDI (PT003) 14.4/9.6 μg ex-actuator | Intervention Type: DRUG; Name: BFF MDI (PT009) 320/9.6 μg; Assigned to Arm(s): BFF MDI (PT009) 320/9.6 μg ex-actuator | Intervention Type: DRUG; Name: Symbicort® Turbuhaler® (TBH) Inhalation Powder; Assigned to Arm(s): Symbicort
C: Arm Label: CHF 5993 + Ultibro matched placebo; Type: EXPERIMENTAL; Interventions: Drug: CHF 5993 + Ultibro matched placebo, Procedure: Central spirometry, Other: COPD assessment test, Procedure: Local laboratory Assessments, Other: Saint George's Respiratory Questionnaire, Other: EXACT-pro questionnaire | Arm Label: Ultibro + CHF 5993 matched placebo; Type: ACTIVE_COMPARATOR; Interventions: Drug: Ultibro + CHF 5993 matched placebo, Procedure: Central spirometry, Other: COPD assessment test, Procedure: Local laboratory Assessments, Other: Saint George's Respiratory Questionnaire, Other: EXACT-pro questionnaire | Intervention Type: DRUG; Name: CHF 5993 + Ultibro matched placebo; Assigned to Arm(s): CHF 5993 + Ultibro matched placebo | Intervention Type: DRUG; Name: Ultibro + CHF 5993 matched placebo; Assigned to Arm(s): Ultibro + CHF 5993 matched placebo | Intervention Type: PROCEDURE; Name: Central spirometry; Assigned to Arm(s): CHF 5993 + Ultibro matched placebo, Ultibro + CHF 5993 matched placebo | Intervention Type: OTHER; Name: COPD assessment test; Assigned to Arm(s): CHF 5993 + Ultibro matched placebo, Ultibro + CHF 5993 matched placebo | Intervention Type: PROCEDURE; Name: Local laboratory Assessments; Assigned to Arm(s): CHF 5993 + Ultibro matched placebo, Ultibro + CHF 5993 matched placebo | Intervention Type: OTHER; Name: Saint George's Respiratory Questionnaire; Assigned to Arm(s): CHF 5993 + Ultibro matched placebo, Ultibro + CHF 5993 matched placebo | Intervention Type: OTHER; Name: EXACT-pro questionnaire; Assigned to Arm(s): CHF 5993 + Ultibro matched placebo, Ultibro + CHF 5993 matched placebo
D: Arm Label: QVA149; Type: EXPERIMENTAL; Interventions: Drug: QVA149 | Arm Label: Tiotropium + salmeterol/fluticasone; Type: ACTIVE_COMPARATOR; Interventions: Drug: Tiotropium, Drug: Salmeterol/fluticasone | Intervention Type: DRUG; Name: QVA149; Assigned to Arm(s): QVA149 | Intervention Type: DRUG; Name: Tiotropium; Assigned to Arm(s): Tiotropium + salmeterol/fluticasone | Intervention Type: DRUG; Name: Salmeterol/fluticasone; Assigned to Arm(s): Tiotropium + salmeterol/fluticasone

Answer: D