Please select the eligibility criteria that correspond to the clinical trial below.
Title: Primary Care Internet Based Depression Prevention for Adolescents (Promoting AdolescenT Health-PATH)
Brief Summary: The purpose of this randomized multiple-site clinical study is to determine whether a revised CATCH-IT (Internet-based depression prevention program) is more effective than a general health education Internet intervention (Health Education)on teens ages 13-18 (inclusive). It is hypothesized that teens in CATCH-IT will exhibit lower levels of depressed mood and/or maintain lower depressive scores over 2 years long-term follow up as compared to teens in Health Education group.


Options:
A: Inclusion Criteria:

Adolescents:

(A) Youth ages 13 through 18 who are English speaking. (B) Youth must be experiencing elevated level of depressive symptoms on the Center for Epidemiologic Studies Depression (CES-D) scale (score \>/= 16). (C) Youth will be included if they have a past history of depression, anxiety, externalizing symptoms, or substance abuse. Youth presenting in partial remission from a major depressive episode at Baseline will be rescreened after 2 months utilizing the phone screen to ensure episode is fully remitted prior to randomization or access to study intervention. Those who do not fully remit after two months will be excluded.

Parents:

\*Parent of eligible adolescents

Physicians (PCP) or NP:

\*Physician in any of the study sites

Healthcare Professionals:

\*Primary care practice for a minimum of 6 months

Exclusion Criteria:

Adolescents:

* Current DSM-IV diagnosis of Major Depressive Disorder
* Current therapy for depression, or be taking antidepressants (e.g., SSRIs, TCAs, MAOIs, bupropion, nefazodone, mirtazapine, venlafaxine);
* Current CES-D score \>35;
* DSM-IV diagnosis of schizophrenia (current or past) or bipolar affective disorder;
* Current serious medical illness that causes significant disability or dysfunction;
* Significant reading impairment (a minimum sixth-grade reading level based on parental report), mental retardation, or developmental disabilities;
* Serious imminent suicidal risk (as determined by endorsement of current suicide on CES-D or in KSADS interview) or other conditions that may require immediate psychiatric hospitalization
* Psychotic features or disorders, or currently be receiving psychotropic medication
* Extreme, current drug/alcohol abuse (greater than or equal to 2 on the CRAFFT).

Parents:

* Ineligible child
* Non-English speaking

Physicians:

\*None

Healthcare Professionals:

\*None
B: Inclusion Criteria:

* At least one parent who meets diagnostic criteria for a current (or past, during the child's lifetime) diagnosis of depression
* The participating child is aged 8-17
* The participating child has an IQ of at least 85
* Both child and parent(s) have adequate German-language skills
* Both child and parents consent to intervention sessions being video-recorded

Exclusion Criteria:

* The participating parent(s) has current symptoms of bipolar disorder, psychotic symptoms, personality disorder, substance addiction, or is suicidal
* The participating child meets criteria for a current, or previous, episode of any psychiatric disorder
* The participating child is undergoing or has undergone treatment for depression
* The participating child or parent have serious symptoms of a disorder (or are in crisis) that may hamper their ability to take part in the study
C: Inclusion Criteria:

* age 15-21 years and
* two risk factors for developing depression in the next two years:

  * Center for Epidemiologic Studies-Depression (CES-D) score \> 12 and either a family history or past personal history of depression.
  * Exclusion criteria include meeting criteria or undergoing active treatment for M. depression, or having suicidal ideation

Exclusion Criteria:

* undergoing active treatment for M. depression, or having suicidal ideation
D: Inclusion Criteria:

* Aged 14 - 24 years of age
* Proficient English
* Patients must be deemed to have an emotional/mental health concern by their GP or be screened to have at least a mild mental health problem (a score of 16 or above) on the K10 Symptom Scale

Exclusion Criteria:

* Severe psychiatric or medical condition that prevents the person from complying with either the requirements of informed consent or the study protocol.
* Young people referred to a mental health specialist by their GP will be excluded only if they obtain a specialist appointment during the mobiletype study period (2 - 4 weeks).

Answer: A