TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Interventional Left Atrial Appendage Closure vs. Novel Anticoagulation Agents in High-risk Patients With Atrial Fibrillation (PRAGUE-17 Study)
Brief Summary: Atrial fibrillation (AF) is the most common cardiac arrhythmia with a prevalence of 1-2%. Without antithrombotic treatment, the annual risk of a cardioembolic event is 5-6%. The source of a cardioembolic event is a thrombus, which usually forms in the left atrial appendage (LAA). The prevention of cardioembolic events involves treatment with anticoagulant drugs, which were limited to, until recently, vitamin K antagonists (e.g. warfarin). Anticoagulant treatment with warfarin can lead to adverse bleeding events, some of which can be life threatening. Recently, two new options for thrombus prevention have been developed. The first is the novel anticoagulants (NOAC), which were associated with slightly better safety profiles due to a lower frequency of intracranial bleeding in large randomized trials . The second option involves interventional occlusion of the LAA. The aim of this project is to compare the LAA occlusion intervention to NOAC pharmacological treatment in a randomized multicenter study of AF patients at high risk of a cardioembolic event.


Options:
A: Arm Label: LAAO group; Type: EXPERIMENTAL; Interventions: Device: Left atrial appendage closure | Arm Label: NOAC group; Type: EXPERIMENTAL; Interventions: Drug: NOAC | Intervention Type: DRUG; Name: NOAC; Assigned to Arm(s): NOAC group | Intervention Type: DEVICE; Name: Left atrial appendage closure; Assigned to Arm(s): LAAO group
B: Arm Label: Edoxaban 60/30mg daily; Type: EXPERIMENTAL; Interventions: Drug: Edoxaban | Arm Label: Non-anticoagulant medical therapy; Type: ACTIVE_COMPARATOR; Interventions: Other: Non-anticoagulant medical therapy | Intervention Type: DRUG; Name: Edoxaban; Assigned to Arm(s): Edoxaban 60/30mg daily | Intervention Type: OTHER; Name: Non-anticoagulant medical therapy; Assigned to Arm(s): Non-anticoagulant medical therapy
C: Arm Label: Triple Pill (active treatment); Type: EXPERIMENTAL; Interventions: Drug: telmisartan 20mg, amlodipine 2.5mg, and indapamide 1.25mg | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: telmisartan 20mg, amlodipine 2.5mg, and indapamide 1.25mg; Assigned to Arm(s): Triple Pill (active treatment) | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
D: Arm Label: low weight molecular heparin; Type: EXPERIMENTAL; Interventions: Drug: Enoxaparin | Arm Label: standard therapy; Type: PLACEBO_COMPARATOR; Interventions: Other: Graduated compression stockings and/or intermittent pneumatic compression and/or early mobilization | Intervention Type: DRUG; Name: Enoxaparin; Assigned to Arm(s): low weight molecular heparin | Intervention Type: OTHER; Name: Graduated compression stockings and/or intermittent pneumatic compression and/or early mobilization; Assigned to Arm(s): standard therapy

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Conducting Outreach to Improve Cervical Cancer Screening Rates Among Underscreened Patients at an Urban Community Health Center
Brief Summary: The purpose of this project is to determine whether outreach to HIV-negative patients who are overdue for a Pap smear at a New England urban community health center can increase cervical cancer screening rates. It additionally seeks to determine which form of outreach - via letter, email, phone, or a mixture of those modalities- is most effective among these patients.


Options:
A: Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Low Intensity Information (DVD); Type: ACTIVE_COMPARATOR; Interventions: Behavioral: DVD | Arm Label: High Intensity Information (Promotora); Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Promotora | Intervention Type: BEHAVIORAL; Name: DVD; Assigned to Arm(s): Low Intensity Information (DVD) | Intervention Type: BEHAVIORAL; Name: Promotora; Assigned to Arm(s): High Intensity Information (Promotora)
B: Arm Label: CHWs facilitated Self-Sampling; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: CHW and Self-sampling for Cervical Cancer | Arm Label: Mailed Self-Sampler; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Mailed Self Sampler | Intervention Type: BEHAVIORAL; Name: CHW and Self-sampling for Cervical Cancer; Assigned to Arm(s): CHWs facilitated Self-Sampling | Intervention Type: BEHAVIORAL; Name: Mailed Self Sampler; Assigned to Arm(s): Mailed Self-Sampler
C: Arm Label: Usual care / opportunistic screening; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Letter and informational sheet; Type: EXPERIMENTAL; Interventions: Other: Letter and informational sheet | Arm Label: Email; Type: EXPERIMENTAL; Interventions: Other: Email | Arm Label: Phone; Type: EXPERIMENTAL; Interventions: Other: Phone | Arm Label: Multimodal; Type: EXPERIMENTAL; Interventions: Other: Multimodal | Intervention Type: OTHER; Name: Letter and informational sheet; Assigned to Arm(s): Letter and informational sheet | Intervention Type: OTHER; Name: Email; Assigned to Arm(s): Email | Intervention Type: OTHER; Name: Phone; Assigned to Arm(s): Phone | Intervention Type: OTHER; Name: Multimodal; Assigned to Arm(s): Multimodal
D: Arm Label: Early Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Lay health advisor visits and newsletter | Arm Label: Delayed Intervention; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Lay health advisor visits and newsletter; Assigned to Arm(s): Early Intervention

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Tailored Peer-Based Sleep Health Education and Social Support Among Blacks With Obstructive Sleep Apnea
Brief Summary: The primary purpose of this study is to ascertain the effectiveness of tailored, peer based sleep health education and social support in increasing adherence rates to recommended Obstructive Sleep Apnea (OSA) evaluation and treatment among blacks at risk of Obstructive Sleep Apnea.


Options:
A: Arm Label: OSA Health Education & Support Group; Type: EXPERIMENTAL; Interventions: Behavioral: Peer Based Sleep Health Education and Social Support | Arm Label: Attention Control Group; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Attention Control Group | Intervention Type: BEHAVIORAL; Name: Peer Based Sleep Health Education and Social Support; Assigned to Arm(s): OSA Health Education & Support Group | Intervention Type: BEHAVIORAL; Name: Attention Control Group; Assigned to Arm(s): Attention Control Group
B: Arm Label: 1; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Device: CPAP | Intervention Type: DEVICE; Name: CPAP; Assigned to Arm(s): 2
C: Arm Label: CPAP; Type: EXPERIMENTAL; Interventions: Device: CPAP, Other: Standard care for OSA | Arm Label: Standard care for OSA; Type: ACTIVE_COMPARATOR; Interventions: Other: Standard care for OSA | Intervention Type: DEVICE; Name: CPAP; Assigned to Arm(s): CPAP | Intervention Type: OTHER; Name: Standard care for OSA; Assigned to Arm(s): CPAP, Standard care for OSA
D: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Drug: Losartan | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Drug: Losartan | Arm Label: 3; Type: EXPERIMENTAL; Interventions: Drug: Losartan, Other: CPAP | Intervention Type: DRUG; Name: Losartan; Assigned to Arm(s): 1, 2, 3 | Intervention Type: OTHER; Name: CPAP; Assigned to Arm(s): 3

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Evaluation of a Transition Intervention for Family Caregivers of Persons With Alzheimer Disease and Multiple Chronic Conditions
Brief Summary: With the number of Canadians with Alzheimer's disease and related dementias (ADRD) growing, supporting family care partners of persons with ADRD is critical. Family caregivers provide about 90 per cent of in-home care for persons with ADRD, and the care is often difficult due to co-morbidities in persons with ADRD. Family caregivers of older persons with ADRD and multiple chronic conditions (MCC) experience significant, complex, distressing transitions such as changes to their environment, roles and relationships, physical and mental health, isolation, and taking on new tasks. An online Transition Toolkit (My Tools 4 Care) was developed for family caregivers of persons with ADRD and MCC living at home, to support caregivers through transitions and increase their self-efficacy, hope, and quality of life (QOL).

Through this pragmatic mixed methods randomized controlled trial the investigators expect to find that family caregivers receiving the online My Tools 4 Care Toolkit will show greater improvement in hope, self-efficacy and QOL, at no additional cost from a societal perspective, compared with those in an educational control group. Following baseline data collection 180 participants will be randomly assigned to one of the groups with repeated measures at one, three and six months.


Options:
A: Arm Label: Immediately Receive Tool; Type: EXPERIMENTAL; Interventions: Behavioral: Immediately Receive Tool | Arm Label: One Month Delay; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: One Month Delay | Intervention Type: BEHAVIORAL; Name: Immediately Receive Tool; Assigned to Arm(s): Immediately Receive Tool | Intervention Type: BEHAVIORAL; Name: One Month Delay; Assigned to Arm(s): One Month Delay
B: Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: My Tools 4 Care | Arm Label: Educational Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: My Tools 4 Care; Assigned to Arm(s): Intervention
C: Arm Label: iSupport for dementia - European-Portuguese version; Type: EXPERIMENTAL; Interventions: Behavioral: iSupport for dementia - European-Portuguese version | Arm Label: Education-only e-book; Type: ACTIVE_COMPARATOR; Interventions: Other: e-book (comparator) | Intervention Type: BEHAVIORAL; Name: iSupport for dementia - European-Portuguese version; Assigned to Arm(s): iSupport for dementia - European-Portuguese version | Intervention Type: OTHER; Name: e-book (comparator); Assigned to Arm(s): Education-only e-book
D: Arm Label: Active treatment; Type: EXPERIMENTAL; Interventions: Behavioral: Video-based coping skills training with telephone coaching | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Video-based coping skills training with telephone coaching; Assigned to Arm(s): Active treatment

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Clinical Evaluation of the Eclipse™ System, a Vaginal Bowel Control (VBC) Therapy for Fecal Incontinence in Women
Brief Summary: Multi-center, prospective, within-subject control, open label clinical trial to evaluate the durability of the safety and effectiveness of the Eclipse™ System after 3 and 12 months of use.


Options:
A: Arm Label: Treatment; Type: EXPERIMENTAL; Interventions: Device: Eclipse™ System | Intervention Type: DEVICE; Name: Eclipse™ System; Assigned to Arm(s): Treatment
B: Arm Label: Salpingectomy group; Type: EXPERIMENTAL; Interventions: Procedure: Salpingectomy | Arm Label: No Salpingectomy Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: PROCEDURE; Name: Salpingectomy; Assigned to Arm(s): Salpingectomy group
C: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Arm Label: Iltamiocel; Type: EXPERIMENTAL; Interventions: Biological: Iltamiocel | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Placebo | Intervention Type: BIOLOGICAL; Name: Iltamiocel; Assigned to Arm(s): Iltamiocel
D: Arm Label: Salpingectomy with delayed oophorectomy; Type: EXPERIMENTAL; Interventions: Procedure: Salpingectomy with delayed oophorectomy | Arm Label: Risk-reducing salpingo-oophorectomy; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Risk-reducing salpingo-oophorectomy | Intervention Type: PROCEDURE; Name: Salpingectomy with delayed oophorectomy; Assigned to Arm(s): Salpingectomy with delayed oophorectomy | Intervention Type: PROCEDURE; Name: Risk-reducing salpingo-oophorectomy; Assigned to Arm(s): Risk-reducing salpingo-oophorectomy

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Program SI! for Cardiovascular Health Promotion for Elementary Students Aged 6 to 11: a Cluster Randomized Trial
Brief Summary: The objective of the study is to evaluate the effects of Program SI! for Elementary in different times of exposure for childrens and their immediate environment (teachers and parents). For this purpose, 48 public schools from the Community of Madrid-South Area (Spain) were randomly assigned to Program SI! during 3 or 6 academic years (intervention group) or keep their normal curriculum (control group). The main outcome is 3-year, and 6-year changes from baseline of questionnaire scoring of children, their parents and teachers in regards to a healthy lifestyle. For children were included 3-year, and 6-year changes of cardiovascular markers derived from blood pressure and anthropometry.


Options:
A: Arm Label: New Moves Intervention Group; Type: EXPERIMENTAL; Interventions: Behavioral: New Moves | Arm Label: control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: New Moves; Assigned to Arm(s): New Moves Intervention Group
B: Arm Label: A Intervention group; Type: EXPERIMENTAL; Interventions: Behavioral: Increased physical education in primary school (daily) | Arm Label: B Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Increased physical education in primary school (daily); Assigned to Arm(s): A Intervention group
C: Arm Label: Physical activity intervention group; Type: EXPERIMENTAL; Interventions: Behavioral: Physical Activity | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Physical Activity; Assigned to Arm(s): Physical activity intervention group
D: Arm Label: Program SI! for Elementary 6 levels; Type: EXPERIMENTAL; Interventions: Behavioral: PSIE13, Behavioral: PSIE46 | Arm Label: Normal curriculum; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Program SI! for Elementary first levels; Type: EXPERIMENTAL; Interventions: Behavioral: PSIE13 | Arm Label: Program SI! for Elementary last levels; Type: EXPERIMENTAL; Interventions: Behavioral: PSIE46 | Intervention Type: BEHAVIORAL; Name: PSIE13; Assigned to Arm(s): Program SI! for Elementary 6 levels, Program SI! for Elementary first levels | Intervention Type: BEHAVIORAL; Name: PSIE46; Assigned to Arm(s): Program SI! for Elementary 6 levels, Program SI! for Elementary last levels

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Text Message Reminders for Influenza Vaccine in Pregnancy
Brief Summary: Influenza virus accounts for numerous cases (epidemics) of respiratory illnesses each year worldwide and affects people of all ages. These epidemics typically occur in the winter months, and can result in substantial morbidity and mortality in persons at risk. Pregnant women may be more susceptible to morbidity and mortality associated with influenza infection. This increased risk may result from several factors including increased heart rate, stroke volume, and oxygen consumption, decreased lung capacity, and changes in immunologic function. Immunization of women during pregnancy can help to prevent infection in the woman herself and may also offer protection to the infant in two ways: by the passage of antibodies from mother to the fetus during pregnancy, and by preventing infection in the mother and therefore decreasing the infant's exposure risk after birth. In Canada, the National Advisory Committee on Immunization (NACI) recommends the vaccine for pregnant women who are expected to deliver during influenza season because they will become household contacts of their newborn. Ideal timing of vaccination occurs in October or November since influenza outbreaks typically occur throughout the winter months. Despite the Canadian and American guidelines for influenza vaccination during pregnancy, it is unclear how many women are offered and/or actually receive the vaccine while pregnant. There is, however, evidence that women will accept the vaccine if offered. Specifically, in the Women's Health Care Centre at St. Michael's Hospital, it was found that 42% of women not only accepted but also received the influenza vaccination when offered. Innovative techniques will be required to continue to increase vaccination rates among vulnerable populations, including pregnant women. The purpose of the present study is to determine if the use of electronic reminders (text messages) increases the likelihood of receiving the influenza vaccine among pregnant women.


Options:
A: Arm Label: Intense follow up; Type: EXPERIMENTAL; Interventions: Behavioral: intense follow up | Arm Label: standard follow-up; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: intense follow up; Assigned to Arm(s): Intense follow up
B: N/A
C: Arm Label: Nutrition messages; Type: EXPERIMENTAL; Interventions: Behavioral: SMS | Arm Label: General health messages; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: SMS | Intervention Type: BEHAVIORAL; Name: SMS; Assigned to Arm(s): General health messages, Nutrition messages
D: Arm Label: Standard Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Text Messages; Type: EXPERIMENTAL; Interventions: Other: Daily Text Messages | Intervention Type: OTHER; Name: Daily Text Messages; Assigned to Arm(s): Text Messages

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Text Message Reminders for Influenza Vaccine in Pregnancy
Brief Summary: Influenza virus accounts for numerous cases (epidemics) of respiratory illnesses each year worldwide and affects people of all ages. These epidemics typically occur in the winter months, and can result in substantial morbidity and mortality in persons at risk. Pregnant women may be more susceptible to morbidity and mortality associated with influenza infection. This increased risk may result from several factors including increased heart rate, stroke volume, and oxygen consumption, decreased lung capacity, and changes in immunologic function. Immunization of women during pregnancy can help to prevent infection in the woman herself and may also offer protection to the infant in two ways: by the passage of antibodies from mother to the fetus during pregnancy, and by preventing infection in the mother and therefore decreasing the infant's exposure risk after birth. In Canada, the National Advisory Committee on Immunization (NACI) recommends the vaccine for pregnant women who are expected to deliver during influenza season because they will become household contacts of their newborn. Ideal timing of vaccination occurs in October or November since influenza outbreaks typically occur throughout the winter months. Despite the Canadian and American guidelines for influenza vaccination during pregnancy, it is unclear how many women are offered and/or actually receive the vaccine while pregnant. There is, however, evidence that women will accept the vaccine if offered. Specifically, in the Women's Health Care Centre at St. Michael's Hospital, it was found that 42% of women not only accepted but also received the influenza vaccination when offered. Innovative techniques will be required to continue to increase vaccination rates among vulnerable populations, including pregnant women. The purpose of the present study is to determine if the use of electronic reminders (text messages) increases the likelihood of receiving the influenza vaccine among pregnant women.


Options:
A: N/A
B: Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Intervention (text); Type: EXPERIMENTAL; Interventions: Behavioral: SmokefreeMOM Text | Arm Label: Intervention Plus (text+quitline); Type: EXPERIMENTAL; Interventions: Behavioral: SmokefreeMOM Text | Intervention Type: BEHAVIORAL; Name: SmokefreeMOM Text; Assigned to Arm(s): Intervention (text), Intervention Plus (text+quitline)
C: Arm Label: WelTel SMS service; Type: EXPERIMENTAL; Interventions: Behavioral: WelTel SMS service | Arm Label: Standard care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: WelTel SMS service; Assigned to Arm(s): WelTel SMS service
D: Arm Label: mHealth; Type: EXPERIMENTAL; Interventions: Other: mHealth | Arm Label: No mHealth; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: mHealth; Assigned to Arm(s): mHealth

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Community-based Rehabilitation Training After Stroke: a Pilot Randomised Controlled Trial
Brief Summary: A pilot study that will evaluate the feasibility and acceptability of procedures to inform the design and delivery of a definitive RCT of ReTrain (which would assess the clinical and cost effectiveness of ReTrain for stroke survivors).


Options:
A: Arm Label: TheraTogs; Type: EXPERIMENTAL; Interventions: Device: TheraTogs | Arm Label: Cane walking; Type: ACTIVE_COMPARATOR; Interventions: Device: Cane walking | Intervention Type: DEVICE; Name: TheraTogs; Assigned to Arm(s): TheraTogs | Intervention Type: DEVICE; Name: Cane walking; Assigned to Arm(s): Cane walking
B: Arm Label: Rehabilitation training; Type: EXPERIMENTAL; Interventions: Other: Rehabilitation | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Rehabilitation; Assigned to Arm(s): Rehabilitation training
C: Arm Label: Control group; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Follow-up control group | Arm Label: Aerobic exercise group; Type: EXPERIMENTAL; Interventions: Behavioral: Aerobic exercise group, Behavioral: Follow-up first aerobic exercise group, Behavioral: Follow-up second aerobic exercise group | Arm Label: Follow-up first aerobic exercise group; Type: EXPERIMENTAL; Interventions: Behavioral: Follow-up first aerobic exercise group | Arm Label: Follow-up control group; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Control group, Behavioral: Follow-up control group | Arm Label: Follow-up second aerobic exercise group; Type: EXPERIMENTAL; Interventions: Behavioral: Follow-up second aerobic exercise group | Intervention Type: BEHAVIORAL; Name: Aerobic exercise group; Assigned to Arm(s): Aerobic exercise group | Intervention Type: BEHAVIORAL; Name: Control group; Assigned to Arm(s): Follow-up control group | Intervention Type: BEHAVIORAL; Name: Follow-up first aerobic exercise group; Assigned to Arm(s): Aerobic exercise group, Follow-up first aerobic exercise group | Intervention Type: BEHAVIORAL; Name: Follow-up control group; Assigned to Arm(s): Control group, Follow-up control group | Intervention Type: BEHAVIORAL; Name: Follow-up second aerobic exercise group; Assigned to Arm(s): Aerobic exercise group, Follow-up second aerobic exercise group
D: Arm Label: Intervention; Type: ACTIVE_COMPARATOR; Interventions: Other: STARFISH | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: STARFISH; Assigned to Arm(s): Intervention

Answer: B