Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A 52-Week, Multi-Centre, Randomised, Parallel-Group, Double-Blind, Active Controlled, Phase IV Study to Evaluate the Safety and Efficacy of Dapagliflozin or Dapagliflozin Plus Saxagliptin Compared With Sulphonylurea All Given as Add-on Therapy to Metformin in Adult Patients With Type 2 Diabetes Who Have Inadequate Glycaemic Control on Metformin Monotherapy
Brief Summary: This study is being carried out to see if dapagliflozin and dapagliflozin plus saxagliptin as an addition to metformin is effective and safe in treating patients with type 2 diabetes when compared to glimepiride (sulphonylurea) as an addition to metformin treatment.


Options:
A: Arm Label: Saxagliptin, 5 mg + insulin; Type: EXPERIMENTAL; Interventions: Drug: Saxagliptin, 5 mg + insulin | Arm Label: Placebo + insulin; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo + insulin | Intervention Type: DRUG; Name: Saxagliptin, 5 mg + insulin; Assigned to Arm(s): Saxagliptin, 5 mg + insulin | Intervention Type: DRUG; Name: Placebo + insulin; Assigned to Arm(s): Placebo + insulin
B: Arm Label: BI 10773 low dose; Type: EXPERIMENTAL; Interventions: Drug: BI 10773, Drug: Placebo (high dose) | Arm Label: BI 10773 high dose; Type: EXPERIMENTAL; Interventions: Drug: Placebo (low dose), Drug: BI 10773 | Arm Label: Metformin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Metformin | Intervention Type: DRUG; Name: Metformin; Assigned to Arm(s): Metformin | Intervention Type: DRUG; Name: BI 10773; Assigned to Arm(s): BI 10773 low dose | Intervention Type: DRUG; Name: Placebo (low dose); Assigned to Arm(s): BI 10773 high dose | Intervention Type: DRUG; Name: BI 10773; Assigned to Arm(s): BI 10773 high dose | Intervention Type: DRUG; Name: Placebo (high dose); Assigned to Arm(s): BI 10773 low dose
C: Arm Label: Ertuglifozin 5 mg; Type: EXPERIMENTAL; Interventions: Drug: Ertugliflozin 5 mg, Drug: Placebo to Ertugliflozin, Other: Glimepiride, Drug: Placebo to Glimepiride, Biological: Basal Insulin, Drug: Metformin | Arm Label: Ertugliflozin 15 mg; Type: EXPERIMENTAL; Interventions: Drug: Ertugliflozin 15 mg, Other: Glimepiride, Drug: Placebo to Glimepiride, Biological: Basal Insulin, Drug: Metformin | Arm Label: Placebo/Glimepiride; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo to Ertugliflozin, Other: Glimepiride, Biological: Basal Insulin, Drug: Metformin | Intervention Type: DRUG; Name: Ertugliflozin 5 mg; Assigned to Arm(s): Ertuglifozin 5 mg | Intervention Type: DRUG; Name: Ertugliflozin 15 mg; Assigned to Arm(s): Ertugliflozin 15 mg | Intervention Type: DRUG; Name: Placebo to Ertugliflozin; Assigned to Arm(s): Ertuglifozin 5 mg, Placebo/Glimepiride | Intervention Type: OTHER; Name: Glimepiride; Assigned to Arm(s): Ertugliflozin 15 mg, Ertuglifozin 5 mg, Placebo/Glimepiride | Intervention Type: DRUG; Name: Placebo to Glimepiride; Assigned to Arm(s): Ertugliflozin 15 mg, Ertuglifozin 5 mg | Intervention Type: BIOLOGICAL; Name: Basal Insulin; Assigned to Arm(s): Ertugliflozin 15 mg, Ertuglifozin 5 mg, Placebo/Glimepiride | Intervention Type: DRUG; Name: Metformin; Assigned to Arm(s): Ertugliflozin 15 mg, Ertuglifozin 5 mg, Placebo/Glimepiride
D: Arm Label: Dapagliflozin+metformin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Dapagliflozin, Drug: Placebo for saxagliptin, Drug: Placebo for glimepiride | Arm Label: Dapagliflozin+saxagliptin+metformin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Dapagliflozin, Drug: Saxagliptin, Drug: Placebo for glimepiride | Arm Label: Glimepiride+metformin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Glimepiride, Drug: Placebo for dapagliflozin, Drug: Placebo for saxagliptin | Intervention Type: DRUG; Name: Dapagliflozin; Assigned to Arm(s): Dapagliflozin+metformin, Dapagliflozin+saxagliptin+metformin | Intervention Type: DRUG; Name: Saxagliptin; Assigned to Arm(s): Dapagliflozin+saxagliptin+metformin | Intervention Type: DRUG; Name: Glimepiride; Assigned to Arm(s): Glimepiride+metformin | Intervention Type: DRUG; Name: Placebo for dapagliflozin; Assigned to Arm(s): Glimepiride+metformin | Intervention Type: DRUG; Name: Placebo for saxagliptin; Assigned to Arm(s): Dapagliflozin+metformin, Glimepiride+metformin | Intervention Type: DRUG; Name: Placebo for glimepiride; Assigned to Arm(s): Dapagliflozin+metformin, Dapagliflozin+saxagliptin+metformin

Answer: D