Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Improving the Population-Wide Effectiveness of U.S. Tobacco Cessation Quitlines
Brief Summary: Research shows that smoking cessation is the most significant preventable health behavior change that a person can make to lower cancer risk. In addition, telephone quitlines are an effective, science-based smoking cessation treatment that is universally accessible to smokers in the U.S. However, little research has explored promising approaches that could increase quitline use, improve quit rates, and inform resource allocation for quitline services. The proposed study will test three promising enhancements to the standard quitline treatment that typically consists of counseling and, possibly 2 weeks of a NRT medication. These enhancements are: 1) combination nicotine replacement therapy as recommended by the United States Public Health Service Clinical Practice Guideline on Treating Tobacco Use and Dependence; 2) extended duration of cessation medication use; and 3) an innovative counseling addition - cognitive medication adherence counseling - to optimize adherence to cessation medication. In addition, the cost-effectiveness of each intervention will be calculated. The findings of the proposed research have broad potential application and relevance to state quitlines, quitline service providers, and other purchasers of quitline services such as employers and insurers. Additionally, the study findings can potentially inform other telephone health behavior counseling programs.


Options:
A: Arm Label: Group I (standard care); Type: ACTIVE_COMPARATOR; Interventions: Other: Laboratory Biomarker Analysis, Behavioral: Smoking Cessation Intervention | Arm Label: Group II (enhanced care); Type: EXPERIMENTAL; Interventions: Other: Laboratory Biomarker Analysis, Behavioral: Smoking Cessation Intervention, Other: Tobacco Cessation Counseling | Arm Label: Group III (intensive care); Type: EXPERIMENTAL; Interventions: Other: Laboratory Biomarker Analysis, Behavioral: Smoking Cessation Intervention, Behavioral: Telephone-Based Intervention, Other: Tobacco Cessation Counseling | Intervention Type: OTHER; Name: Laboratory Biomarker Analysis; Assigned to Arm(s): Group I (standard care), Group II (enhanced care), Group III (intensive care) | Intervention Type: BEHAVIORAL; Name: Smoking Cessation Intervention; Assigned to Arm(s): Group I (standard care), Group II (enhanced care), Group III (intensive care) | Intervention Type: BEHAVIORAL; Name: Telephone-Based Intervention; Assigned to Arm(s): Group III (intensive care) | Intervention Type: OTHER; Name: Tobacco Cessation Counseling; Assigned to Arm(s): Group II (enhanced care), Group III (intensive care)
B: Arm Label: 2 Weeks of Nicotine Patch Only, No CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch | Arm Label: 2 Weeks of Nicotine Patch Only plus CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch, Behavioral: CMAC | Arm Label: 2 Wks Nicotine Patch+Nic Gum, No CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch, Drug: Nicotine gum | Arm Label: 2 Wks Nicotine Patch+Nic Gum plus CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch, Drug: Nicotine gum, Behavioral: CMAC | Arm Label: 6 Weeks of Nicotine Patch Only, No CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch | Arm Label: 6 Weeks of Nicotine Patch Only plus CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch, Behavioral: CMAC | Arm Label: 6 Wks Nicotine Patch+Nic Gum, No CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch, Drug: Nicotine gum | Arm Label: 6 Wks Nicotine Patch+Nic Gum plus CMAC; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine patch, Drug: Nicotine gum, Behavioral: CMAC | Intervention Type: DRUG; Name: Nicotine patch; Assigned to Arm(s): 2 Weeks of Nicotine Patch Only plus CMAC, 2 Weeks of Nicotine Patch Only, No CMAC, 2 Wks Nicotine Patch+Nic Gum plus CMAC, 2 Wks Nicotine Patch+Nic Gum, No CMAC, 6 Weeks of Nicotine Patch Only plus CMAC, 6 Weeks of Nicotine Patch Only, No CMAC, 6 Wks Nicotine Patch+Nic Gum plus CMAC, 6 Wks Nicotine Patch+Nic Gum, No CMAC | Intervention Type: DRUG; Name: Nicotine gum; Assigned to Arm(s): 2 Wks Nicotine Patch+Nic Gum plus CMAC, 2 Wks Nicotine Patch+Nic Gum, No CMAC, 6 Wks Nicotine Patch+Nic Gum plus CMAC, 6 Wks Nicotine Patch+Nic Gum, No CMAC | Intervention Type: BEHAVIORAL; Name: CMAC; Assigned to Arm(s): 2 Weeks of Nicotine Patch Only plus CMAC, 2 Wks Nicotine Patch+Nic Gum plus CMAC, 6 Weeks of Nicotine Patch Only plus CMAC, 6 Wks Nicotine Patch+Nic Gum plus CMAC
C: Intervention Type: BEHAVIORAL; Name: smoking cessation intervention; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: varenicline; Assigned to Arm(s): N/A | Intervention Type: OTHER; Name: counseling intervention; Assigned to Arm(s): N/A | Intervention Type: OTHER; Name: internet-based intervention; Assigned to Arm(s): N/A
D: Arm Label: Intensive behavioral intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Positively Smoke Free | Arm Label: Standard care; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Standard care | Intervention Type: BEHAVIORAL; Name: Positively Smoke Free; Assigned to Arm(s): Intensive behavioral intervention | Intervention Type: BEHAVIORAL; Name: Standard care; Assigned to Arm(s): Standard care

Answer: B