Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Double-blind, Randomised, Placebo and Active Controlled, Parallel Group Study to Evaluate the Analgesic Effect of a Single Oral Administration of Four Different Combination Doses of DKP.TRIS With TRAM.HCL in Comparison With the Single Agents, on Moderate to Severe Pain Following Impacted Third Mandibular Molar Tooth Extraction
Brief Summary: The purpose of this study is to evaluate the analgesic efficacy of Dexketoprofen Trometamol and Tramadol Hydrochloride given in combinations and the analgesic efficacy of each single component in comparison to placebo on moderate to severe pain following impacted third mandibular molar tooth extraction. Ibuprofen will be used as an active control to validate the pain model.


Options:
A: Arm Label: DKP/TRAM followed by DKP/TRAM; Type: EXPERIMENTAL; Interventions: Drug: Dexketoprofen/Tramadol-single dose, Drug: Dexketoprofen/Tramadol-multiple doses | Arm Label: DKP followed by DKP; Type: ACTIVE_COMPARATOR; Interventions: Drug: Dexketoprofen-single dose, Drug: Dexketoprofen-multiple doses | Arm Label: TRAM followed by TRAM; Type: ACTIVE_COMPARATOR; Interventions: Drug: Tramadol-single dose, Drug: Tramadol-multiple doses | Arm Label: Placebo followed by DKP/TRAM; Type: OTHER; Interventions: Drug: Placebo, Drug: Dexketoprofen/Tramadol-multiple doses | Arm Label: Placebo followed by DKP; Type: OTHER; Interventions: Drug: Placebo, Drug: Dexketoprofen-multiple doses | Arm Label: Placebo followed by TRAM; Type: OTHER; Interventions: Drug: Placebo, Drug: Tramadol-multiple doses | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo followed by DKP, Placebo followed by DKP/TRAM, Placebo followed by TRAM | Intervention Type: DRUG; Name: Dexketoprofen-single dose; Assigned to Arm(s): DKP followed by DKP | Intervention Type: DRUG; Name: Tramadol-single dose; Assigned to Arm(s): TRAM followed by TRAM | Intervention Type: DRUG; Name: Dexketoprofen/Tramadol-single dose; Assigned to Arm(s): DKP/TRAM followed by DKP/TRAM | Intervention Type: DRUG; Name: Dexketoprofen-multiple doses; Assigned to Arm(s): DKP followed by DKP, Placebo followed by DKP | Intervention Type: DRUG; Name: Tramadol-multiple doses; Assigned to Arm(s): Placebo followed by TRAM, TRAM followed by TRAM | Intervention Type: DRUG; Name: Dexketoprofen/Tramadol-multiple doses; Assigned to Arm(s): DKP/TRAM followed by DKP/TRAM, Placebo followed by DKP/TRAM
B: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: Ibuprofen; Type: ACTIVE_COMPARATOR; Interventions: Drug: Ibuprofen | Arm Label: TRAM.HCl high dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: Tramadol Hydrochloride | Arm Label: TRAM.HCl low dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: Tramadol Hydrochloride | Arm Label: DKP-TRIS high dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: Dexketoprofen Trometamol | Arm Label: DKP-TRIS low dose; Type: ACTIVE_COMPARATOR; Interventions: Drug: Dexketoprofen Trometamol | Arm Label: DKP-TRIS low dose - TRAM.HCl low dose; Type: EXPERIMENTAL; Interventions: Drug: Dexketoprofen Trometamol + Tramadol Hydrochloride | Arm Label: DKP-TRIS low dose - TRAM.HCl high dose; Type: EXPERIMENTAL; Interventions: Drug: Dexketoprofen Trometamol + Tramadol Hydrochloride | Arm Label: DKP-TRIS high dose - TRAM.HCl low dose; Type: EXPERIMENTAL; Interventions: Drug: Dexketoprofen Trometamol + Tramadol Hydrochloride | Arm Label: DKP-TRIS high dose - TRAM.HCl high dose; Type: EXPERIMENTAL; Interventions: Drug: Dexketoprofen Trometamol + Tramadol Hydrochloride | Intervention Type: DRUG; Name: Dexketoprofen Trometamol; Assigned to Arm(s): DKP-TRIS low dose | Intervention Type: DRUG; Name: Dexketoprofen Trometamol; Assigned to Arm(s): DKP-TRIS high dose | Intervention Type: DRUG; Name: Tramadol Hydrochloride; Assigned to Arm(s): TRAM.HCl low dose | Intervention Type: DRUG; Name: Tramadol Hydrochloride; Assigned to Arm(s): TRAM.HCl high dose | Intervention Type: DRUG; Name: Ibuprofen; Assigned to Arm(s): Ibuprofen | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo | Intervention Type: DRUG; Name: Dexketoprofen Trometamol + Tramadol Hydrochloride; Assigned to Arm(s): DKP-TRIS low dose - TRAM.HCl low dose | Intervention Type: DRUG; Name: Dexketoprofen Trometamol + Tramadol Hydrochloride; Assigned to Arm(s): DKP-TRIS low dose - TRAM.HCl high dose | Intervention Type: DRUG; Name: Dexketoprofen Trometamol + Tramadol Hydrochloride; Assigned to Arm(s): DKP-TRIS high dose - TRAM.HCl low dose | Intervention Type: DRUG; Name: Dexketoprofen Trometamol + Tramadol Hydrochloride; Assigned to Arm(s): DKP-TRIS high dose - TRAM.HCl high dose
C: Arm Label: Dexketoprofen trometamol; Type: EXPERIMENTAL; Interventions: Drug: Dexketoprofen trometamol | Arm Label: Preoperative control; Type: PLACEBO_COMPARATOR; Interventions: Drug: Preoperative control | Intervention Type: DRUG; Name: Dexketoprofen trometamol; Assigned to Arm(s): Dexketoprofen trometamol | Intervention Type: DRUG; Name: Preoperative control; Assigned to Arm(s): Preoperative control
D: Arm Label: DKP/TRAM followed by DKP/TRAM; Type: EXPERIMENTAL; Interventions: Drug: Dexketoprofen/Tramadol-single dose, Drug: Dexketoprofen/Tramadol-multiple doses | Arm Label: DKP followed by DKP; Type: ACTIVE_COMPARATOR; Interventions: Drug: Dexketoprofen-single dose, Drug: Dexketoprofen-multiple doses | Arm Label: TRAM followed by TRAM; Type: ACTIVE_COMPARATOR; Interventions: Drug: Tramadol-single dose, Drug: Tramadol-multiple doses | Arm Label: Placebo followed by DKP/TRAM; Type: OTHER; Interventions: Drug: Placebo, Drug: Dexketoprofen/Tramadol-multiple doses | Arm Label: Placebo followed by DKP; Type: OTHER; Interventions: Drug: Placebo, Drug: Dexketoprofen-multiple doses | Arm Label: Placebo followed by TRAM; Type: OTHER; Interventions: Drug: Placebo, Drug: Tramadol-multiple doses | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo followed by DKP, Placebo followed by DKP/TRAM, Placebo followed by TRAM | Intervention Type: DRUG; Name: Tramadol-single dose; Assigned to Arm(s): TRAM followed by TRAM | Intervention Type: DRUG; Name: Dexketoprofen-single dose; Assigned to Arm(s): DKP followed by DKP | Intervention Type: DRUG; Name: Dexketoprofen/Tramadol-single dose; Assigned to Arm(s): DKP/TRAM followed by DKP/TRAM | Intervention Type: DRUG; Name: Tramadol-multiple doses; Assigned to Arm(s): Placebo followed by TRAM, TRAM followed by TRAM | Intervention Type: DRUG; Name: Dexketoprofen-multiple doses; Assigned to Arm(s): DKP followed by DKP, Placebo followed by DKP | Intervention Type: DRUG; Name: Dexketoprofen/Tramadol-multiple doses; Assigned to Arm(s): DKP/TRAM followed by DKP/TRAM, Placebo followed by DKP/TRAM

Answer: B