TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Effectiveness of High and Low Intensity Intervention for Smoking Cessation During Pregnancy
Brief Summary: The aim of this clinical trial is to test whether offering pregnant smokers a high intensity intervention for smoking cessation increases the rate of smoking cessation at the third trimester of pregnancy, compared to low intensity intervention for smoking cessation that is the usual care, control condition.


Options:
A: Intervention Type: BEHAVIORAL; Name: Nicotine Replacement Therapy; Assigned to Arm(s): N/A
B: Arm Label: High intensity intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Higher intensity intervention | Arm Label: Low intensity intervention; Type: OTHER; Interventions: Behavioral: Low intensity intervention | Intervention Type: BEHAVIORAL; Name: Low intensity intervention; Assigned to Arm(s): Low intensity intervention | Intervention Type: BEHAVIORAL; Name: Higher intensity intervention; Assigned to Arm(s): High intensity intervention
C: Arm Label: Standard support; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Reactive (standard) telephone support | Arm Label: Proactive telephone support; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Proactive telephone support | Arm Label: Standard support & offer NRT; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Reactive (standard) telephone support, Drug: Offer of voucher for cost-free Nicotine Replacement Therapy | Arm Label: Proactive support & offer NRT; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Proactive telephone support, Drug: Offer of voucher for cost-free Nicotine Replacement Therapy | Intervention Type: BEHAVIORAL; Name: Proactive telephone support; Assigned to Arm(s): Proactive support & offer NRT, Proactive telephone support | Intervention Type: BEHAVIORAL; Name: Reactive (standard) telephone support; Assigned to Arm(s): Standard support, Standard support & offer NRT | Intervention Type: DRUG; Name: Offer of voucher for cost-free Nicotine Replacement Therapy; Assigned to Arm(s): Proactive support & offer NRT, Standard support & offer NRT
D: Arm Label: A; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Arm Label: B; Type: EXPERIMENTAL; Interventions: Drug: 2 mg nicotine polacrilex | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): A | Intervention Type: DRUG; Name: 2 mg nicotine polacrilex; Assigned to Arm(s): B

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Effectiveness of High and Low Intensity Intervention for Smoking Cessation During Pregnancy
Brief Summary: The aim of this clinical trial is to test whether offering pregnant smokers a high intensity intervention for smoking cessation increases the rate of smoking cessation at the third trimester of pregnancy, compared to low intensity intervention for smoking cessation that is the usual care, control condition.


Options:
A: Arm Label: MiQuit; Type: EXPERIMENTAL; Interventions: Behavioral: MiQuit | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: MiQuit; Assigned to Arm(s): MiQuit
B: Arm Label: High intensity intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Higher intensity intervention | Arm Label: Low intensity intervention; Type: OTHER; Interventions: Behavioral: Low intensity intervention | Intervention Type: BEHAVIORAL; Name: Low intensity intervention; Assigned to Arm(s): Low intensity intervention | Intervention Type: BEHAVIORAL; Name: Higher intensity intervention; Assigned to Arm(s): High intensity intervention
C: Arm Label: a self help smoking cessation guide; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Guia -a self help smoking cessation guide | Arm Label: couple-based counseling for smoking cessation plus Guia; Type: EXPERIMENTAL; Interventions: Behavioral: couple-based counseling for smoking cessation plus self-help smoking cessation guide | Intervention Type: BEHAVIORAL; Name: couple-based counseling for smoking cessation plus self-help smoking cessation guide; Assigned to Arm(s): couple-based counseling for smoking cessation plus Guia | Intervention Type: BEHAVIORAL; Name: Guia -a self help smoking cessation guide; Assigned to Arm(s): a self help smoking cessation guide
D: Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Computerized brief intervention (5As); Type: EXPERIMENTAL; Interventions: Behavioral: Computer-delivered brief intervention (5As) | Arm Label: Contingency Management Alone; Type: EXPERIMENTAL; Interventions: Behavioral: Contingency Management | Arm Label: Combined Brief Intervention and CM; Type: EXPERIMENTAL; Interventions: Behavioral: Computer-delivered brief intervention (5As), Behavioral: Contingency Management | Intervention Type: BEHAVIORAL; Name: Computer-delivered brief intervention (5As); Assigned to Arm(s): Combined Brief Intervention and CM, Computerized brief intervention (5As) | Intervention Type: BEHAVIORAL; Name: Contingency Management; Assigned to Arm(s): Combined Brief Intervention and CM, Contingency Management Alone

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Effects of Levosimendan on Haemodynamics in Patients Undergoing Elective Aortic Valve Replacement (AVR)Together With Coronary Artery Bypass Grafting
Brief Summary: Patients undergoing aortic valve replacement (AVR) surgery with coronary artery bypass grafting (CABG) are at risk of left ventricular dysfunction. The aim of the study is to describe the haemodynamic effects of levosimendan in comparison to placebo in patients undergoing elective aortic valve replacement (AVR) together with coronary artery bypass grafting (CABG) surgery. The study is randomized, double-blinded, placebo-controlled and will be carried out in Heart Center.

Twenty four patients will be randomized into two groups of 12. The treatment group will receive 24 hour infusion of levosimendan preoperatively where as the placebo group will receive an identical infusion of thiamine coloured glucose. The splanchnic perfusion will be measured by the means of vena hepatica cannulation. CircMon B202 (JR Medical Ltd, Tallinn, Estonia) is used for the measurement of whole-body impedance cardiography derived heart rate, cardiac index, left cardiac work index, systemic vascular resistance index (SVRI), and extracellular water (ECW). Surgical procedure, anaesthesia and cardio protection will be carried out as in standard care. Echo cardiography will be done pre- and postoperatively. Haemodynamics will be recorded hourly and mixed venous saturation every fourth hour for 24 hours.


Options:
A: Arm Label: L; Type: EXPERIMENTAL; Interventions: Drug: levosimendan | Arm Label: P; Type: EXPERIMENTAL; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: levosimendan; Assigned to Arm(s): L | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): P
B: Arm Label: levosimendan; Type: EXPERIMENTAL; Interventions: Drug: levosimendan | Arm Label: placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Intervention Type: DRUG; Name: levosimendan; Assigned to Arm(s): levosimendan | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): placebo
C: Arm Label: Normal saline; Type: PLACEBO_COMPARATOR; Interventions: Drug: Normal saline | Arm Label: Milrinone; Type: ACTIVE_COMPARATOR; Interventions: Drug: Milrinone | Intervention Type: DRUG; Name: Milrinone; Assigned to Arm(s): Milrinone | Intervention Type: DRUG; Name: Normal saline; Assigned to Arm(s): Normal saline
D: Arm Label: Levosimendan; Type: EXPERIMENTAL; Interventions: Drug: Levosimendan | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Levosimendan; Assigned to Arm(s): Levosimendan | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Fluid and Nutrition in Elective Hip Surgery
Brief Summary: The purpose of this study is to determine whether fluid or glucose administration before hip replacement surgery minimizes postoperative muscle breakdown (catabolism), fatigue and disturbances in carbohydrate metabolism.


Options:
A: Arm Label: Fasting; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Fasting. | Arm Label: Water administration; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Water administration | Arm Label: carbohydrate drink; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: carbohydrate drink | Intervention Type: DIETARY_SUPPLEMENT; Name: Water administration; Assigned to Arm(s): Water administration | Intervention Type: DIETARY_SUPPLEMENT; Name: carbohydrate drink; Assigned to Arm(s): carbohydrate drink | Intervention Type: BEHAVIORAL; Name: Fasting.; Assigned to Arm(s): Fasting
B: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Other: Intravenous nutrition with glucose and amino acids | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Other: Intravenous nutrition with glucose and amino acids. | Intervention Type: OTHER; Name: Intravenous nutrition with glucose and amino acids; Assigned to Arm(s): 1 | Intervention Type: OTHER; Name: Intravenous nutrition with glucose and amino acids.; Assigned to Arm(s): 2
C: Arm Label: Test; Type: EXPERIMENTAL; Interventions: Dietary Supplement: PreOP Booster (oral nutritional supplement, food for special medical purposes) | Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: PreOP Booster (oral nutritional supplement, food for special medical purposes) | Intervention Type: DIETARY_SUPPLEMENT; Name: PreOP Booster (oral nutritional supplement, food for special medical purposes); Assigned to Arm(s): Control, Test
D: Arm Label: Aminolaban EN; Type: EXPERIMENTAL; Interventions: Drug: Aminoleban EN | Arm Label: Control; Type: NO_INTERVENTION; Interventions: Drug: Aminoleban EN | Intervention Type: DRUG; Name: Aminoleban EN; Assigned to Arm(s): Aminolaban EN, Control

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The ACTIVE Intervention to Improve Hospice Care
Brief Summary: The ACTIVE Intervention to Improve Hospice Caregiver Pain Management The major goal of this project is to implement and test this promising intervention in three hospice programs. The mixed methods evaluation of this randomized controlled trial (RCT) will provide evidence-based data for a tested intervention manual that hospice staff members can use to integrate the intervention into their practices.


Options:
A: Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Device: OptiMEDs | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: OptiMEDs; Assigned to Arm(s): Intervention
B: Arm Label: HearCARE (Consult+Engage); Type: ACTIVE_COMPARATOR; Interventions: Other: Consult Model, Other: Engage Model | Arm Label: Consult Model; Type: OTHER; Interventions: Other: Consult Model | Intervention Type: OTHER; Name: Consult Model; Assigned to Arm(s): Consult Model, HearCARE (Consult+Engage) | Intervention Type: OTHER; Name: Engage Model; Assigned to Arm(s): HearCARE (Consult+Engage)
C: Arm Label: Advance Care Planning Program; Type: EXPERIMENTAL; Interventions: Other: Implementation of a complex regional Advance Care Planning program | Arm Label: Care as usual; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Implementation of a complex regional Advance Care Planning program; Assigned to Arm(s): Advance Care Planning Program
D: Arm Label: Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: ACTIVE; Type: EXPERIMENTAL; Interventions: Behavioral: ACTIVE | Intervention Type: BEHAVIORAL; Name: ACTIVE; Assigned to Arm(s): ACTIVE

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The ACTIVE Intervention to Improve Hospice Care
Brief Summary: The ACTIVE Intervention to Improve Hospice Caregiver Pain Management The major goal of this project is to implement and test this promising intervention in three hospice programs. The mixed methods evaluation of this randomized controlled trial (RCT) will provide evidence-based data for a tested intervention manual that hospice staff members can use to integrate the intervention into their practices.


Options:
A: Intervention Type: PROCEDURE; Name: family conference with bereavement information leaflet; Assigned to Arm(s): N/A
B: Arm Label: Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: ACTIVE; Type: EXPERIMENTAL; Interventions: Behavioral: ACTIVE | Intervention Type: BEHAVIORAL; Name: ACTIVE; Assigned to Arm(s): ACTIVE
C: Arm Label: standard of care health decision making; Type: ACTIVE_COMPARATOR; Interventions: Other: standard of care | Arm Label: TAILORED intervention; Type: EXPERIMENTAL; Interventions: Other: TAILORED Patient Family Decision Making | Intervention Type: OTHER; Name: TAILORED Patient Family Decision Making; Assigned to Arm(s): TAILORED intervention | Intervention Type: OTHER; Name: standard of care; Assigned to Arm(s): standard of care health decision making
D: Arm Label: communication lecture; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: communication lecture | Arm Label: lecture plus CD-ROM; Type: EXPERIMENTAL; Interventions: Behavioral: lecture plus CD-ROM | Intervention Type: BEHAVIORAL; Name: communication lecture; Assigned to Arm(s): communication lecture | Intervention Type: BEHAVIORAL; Name: lecture plus CD-ROM; Assigned to Arm(s): lecture plus CD-ROM

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Double Blind Combination of Rituximab by Intravenous and Intrathecal Injection Versus Placebo in Patients With Low-Inflammatory Secondary Progressive Multiple Sclerosis (RIVITaLISe)
Brief Summary: Background:

- Secondary-progressive multiple sclerosis (SP-MS) is the chronic phase of multiple sclerosis (MS). The majority of people who have relapsing-remitting MS eventually develop SP-MS. There are currently no effective treatments for SP-MS. Researchers are interested in determining whether the drug rituximab, which is used to treat rheumatoid arthritis and some types of cancer, is able to target certain white blood cells that are thought to play a role in the progression of SP-MS. To ensure that the rituximab will reach the brain and spinal cord, participants will receive it by intravenous drip and by intrathecal injection (through a lumbar puncture into the cerebrospinal fluid).

Objectives:

- To evaluate the safety and effectiveness of combined intravenous and intrathecal rituximab in individuals with secondary-progressive multiple sclerosis.

Eligibility:

- Individuals between 18 and 65 years of age who have been diagnosed with SP-MS and have been off any form of immunosuppressive therapy for at least 3 months.

Design:

- The study will involve a 1-year pretreatment baseline series of visits, followed by a 2-year treatment period. Participants will provide blood samples throughout treatment as directed by the study researchers, and additional studies may be performed during the study period if participants consent to further investigation.


Options:
A: Arm Label: (Placebo and) Glatiramer Acetate; Type: ACTIVE_COMPARATOR; Interventions: Drug: Glatiramer Acetate, Other: Placebo | Arm Label: Rituximab and Glatiramer Acetate (R-GA); Type: EXPERIMENTAL; Interventions: Drug: Rituximab, Drug: Glatiramer Acetate | Intervention Type: DRUG; Name: Rituximab; Assigned to Arm(s): Rituximab and Glatiramer Acetate (R-GA) | Intervention Type: DRUG; Name: Glatiramer Acetate; Assigned to Arm(s): (Placebo and) Glatiramer Acetate, Rituximab and Glatiramer Acetate (R-GA) | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): (Placebo and) Glatiramer Acetate
B: Intervention Type: DRUG; Name: rituximab; Assigned to Arm(s): N/A
C: Arm Label: Rituximab; Type: EXPERIMENTAL; Interventions: Drug: Rituximab | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: normal saline | Arm Label: Baseline; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: Rituximab; Assigned to Arm(s): Rituximab | Intervention Type: OTHER; Name: normal saline; Assigned to Arm(s): Placebo
D: Arm Label: Cohort; Type: N/A; Interventions: Biological: Rituximab | Intervention Type: BIOLOGICAL; Name: Rituximab; Assigned to Arm(s): Cohort

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Prevention of Venous Thromboembolism Disease for Acutelly Ill Medical Patients Admitted to Hospital : Systematic Analysis of Thrombosis Risk Factors and Remember of Prevention Treatment Indications in Emergency Departments.
Brief Summary: The appropriate use of thromboprophylaxis in medical patients admitted to hospital can substantially reduce the overall burden of disease due to venous thromboembolism. However, the use of thromboprophylaxis in medical setting appears to be generally poor leaving at-risk patients unprotected.

We aim to analyse the incidence of symptomatic thromboembolic disease following hospitalisation in medical setting and the efficacy of a multicomponent prevention approach in emergency department including systematic evaluation of thrombosis risk factors and remembers of thrombophylaxis indications and modalities for acutely ill medical patients.

Design: cluster randomized interventional study - Observational study at patient level

Setting: 30 French emergency departments

Patients: Patients over 40 years old admitted in participating emergency departments and hospitalized for acute medical reasons.

Main judgment criteria: the rate of symptomatic thromboembolic events and severe haemorrhage during a formal 3-months follow-up after hospital admission in patients hospitalized at least 48 hours.


Options:
A: Arm Label: A - coded unit ID; Type: EXPERIMENTAL; Interventions: Other: clinical decision support | Arm Label: B - coded unit ID; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: clinical decision support; Assigned to Arm(s): A - coded unit ID
B: Arm Label: Electronic Decision Support; Type: EXPERIMENTAL; Interventions: Behavioral: Decision Support for ARI Management | Arm Label: Paper Decision Support; Type: EXPERIMENTAL; Interventions: Behavioral: Decision Support for ARI Management | Arm Label: Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Decision Support for ARI Management; Assigned to Arm(s): Electronic Decision Support, Paper Decision Support
C: Intervention Type: BEHAVIORAL; Name: smoking cessation intervention; Assigned to Arm(s): N/A | Intervention Type: OTHER; Name: counseling intervention; Assigned to Arm(s): N/A
D: Arm Label: Intervention group; Type: N/A; Interventions: Behavioral: reminders | Arm Label: current practice group; Type: N/A; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: reminders; Assigned to Arm(s): Intervention group

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Prevention of Venous Thromboembolism Disease for Acutelly Ill Medical Patients Admitted to Hospital : Systematic Analysis of Thrombosis Risk Factors and Remember of Prevention Treatment Indications in Emergency Departments.
Brief Summary: The appropriate use of thromboprophylaxis in medical patients admitted to hospital can substantially reduce the overall burden of disease due to venous thromboembolism. However, the use of thromboprophylaxis in medical setting appears to be generally poor leaving at-risk patients unprotected.

We aim to analyse the incidence of symptomatic thromboembolic disease following hospitalisation in medical setting and the efficacy of a multicomponent prevention approach in emergency department including systematic evaluation of thrombosis risk factors and remembers of thrombophylaxis indications and modalities for acutely ill medical patients.

Design: cluster randomized interventional study - Observational study at patient level

Setting: 30 French emergency departments

Patients: Patients over 40 years old admitted in participating emergency departments and hospitalized for acute medical reasons.

Main judgment criteria: the rate of symptomatic thromboembolic events and severe haemorrhage during a formal 3-months follow-up after hospital admission in patients hospitalized at least 48 hours.


Options:
A: Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Educational Reminder | Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Educational Reminder | Intervention Type: BEHAVIORAL; Name: Educational Reminder; Assigned to Arm(s): Control, Intervention
B: Arm Label: LTC Osteoporosis Toolkit Only; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Educ sessions & LTC Osteoporosis toolkit; Type: ACTIVE_COMPARATOR; Interventions: Other: Educ sessions & LTC Osteoporosis toolkit | Intervention Type: OTHER; Name: Educ sessions & LTC Osteoporosis toolkit; Assigned to Arm(s): Educ sessions & LTC Osteoporosis toolkit
C: Arm Label: 1- Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: 2 - Automated Mailing; Type: EXPERIMENTAL; Interventions: Behavioral: Automated Mailing | Arm Label: 3 - Automated Mailing Plus Assisted; Type: EXPERIMENTAL; Interventions: Behavioral: Automated Mailing Plus Assisted | Arm Label: 4 - Auto Plus Assisted Plus Navigation; Type: EXPERIMENTAL; Interventions: Behavioral: Auto Plus Assisted Plus Navigation | Intervention Type: BEHAVIORAL; Name: Automated Mailing; Assigned to Arm(s): 2 - Automated Mailing | Intervention Type: BEHAVIORAL; Name: Automated Mailing Plus Assisted; Assigned to Arm(s): 3 - Automated Mailing Plus Assisted | Intervention Type: BEHAVIORAL; Name: Auto Plus Assisted Plus Navigation; Assigned to Arm(s): 4 - Auto Plus Assisted Plus Navigation
D: Arm Label: Intervention group; Type: N/A; Interventions: Behavioral: reminders | Arm Label: current practice group; Type: N/A; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: reminders; Assigned to Arm(s): Intervention group

Answer: D