Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Phase II Randomised Study Comparing the Tolerance of PICC Line (Peripherally Inserted Central Catheter) and Implanted Port for Adjuvant Chemotherapy in HER2-negative Early Breast Cancer
Brief Summary: Adjuvant chemotherapy is frequently proposed to patients presenting early breast cancer, in case of high risk of recurrence (large tumors, node involvement, high grade...). Due to its toxicity toward veins, chemotherapy must be administered through a central venous device. Today, one can use either an implanted port or a PICC line (Peripherally Inserted Central Catheter). A PICC line is easier to implant and to explant, but has to be flushed every week and may impact daily life (no swimming, some clothes may not fit). On the other hand, a port is subcutaneous and lets patients lead a normal life, but its implant and explant require a cutaneous incision with possible complications (bleeding, pain, infection). For both venous devices, complications such as thrombosis or infection may happen. Published data comparing the two devices are heterogeneous and do not often distinguish patients treated for different diseases at various stages. Empirically in daily practice, for long term use (\>6 months) a port is usually preferred, whereas for short-term treatments (\<6 weeks) a PICC line is used. In the case of Her2 negative early breast cancer, adjuvant chemotherapy usually lasts 4 to 5 months. There is no scientific evidence for preferring one device to the other for these patients.

The aim of this study is to prospectively compare the patients' satisfaction and tolerance of each of the two devices.


Options:
A: Arm Label: PICC line; Type: EXPERIMENTAL; Interventions: Device: Use of a PICC line for chemo administration (PowerPICC SOLO²) | Arm Label: Implanted Port; Type: ACTIVE_COMPARATOR; Interventions: Device: implanted port for chemo administration (X-port isp), Device: Use of a PICC line for chemo administration (PowerPICC SOLO²) | Intervention Type: DEVICE; Name: implanted port for chemo administration (X-port isp); Assigned to Arm(s): Implanted Port | Intervention Type: DEVICE; Name: Use of a PICC line for chemo administration (PowerPICC SOLO²); Assigned to Arm(s): Implanted Port, PICC line
B: Arm Label: Standard technique; Type: ACTIVE_COMPARATOR; Interventions: Other: Standard technique | Arm Label: Ultrasound-guided technique; Type: EXPERIMENTAL; Interventions: Other: Ultrasound-guided technique | Intervention Type: OTHER; Name: Ultrasound-guided technique; Assigned to Arm(s): Ultrasound-guided technique | Intervention Type: OTHER; Name: Standard technique; Assigned to Arm(s): Standard technique
C: Arm Label: Grade 1 Vein Visualization; Type: OTHER; Interventions: Other: IV placement using ultrasound guidance vs traditional method | Arm Label: Grade 2A Vein Visualization; Type: OTHER; Interventions: Other: IV placement using ultrasound guidance vs traditional method | Arm Label: Grade 2b Vein Visualization; Type: OTHER; Interventions: Other: IV placement using ultrasound guidance vs traditional method | Arm Label: Grade 3 Vein Visualization; Type: OTHER; Interventions: Other: IV placement using ultrasound guidance vs traditional method | Intervention Type: OTHER; Name: IV placement using ultrasound guidance vs traditional method; Assigned to Arm(s): Grade 1 Vein Visualization, Grade 2A Vein Visualization, Grade 2b Vein Visualization, Grade 3 Vein Visualization
D: Arm Label: Long Axis approach; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Intravenous access method | Arm Label: Short axis approach; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Intravenous access method | Intervention Type: PROCEDURE; Name: Intravenous access method; Assigned to Arm(s): Long Axis approach, Short axis approach

Answer: A