Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Effects of Maintenance Schedules Following Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease
Brief Summary: Chronic obstructive pulmonary disease (COPD), a preventable and treatable condition, is a major healthcare problem with huge human and economic costs. It affects 3 million people, results in 1.4 million consultations, causes 30,000 deaths, and costs £800M per year in the UK. Considerable research expenditure is devoted to finding new and expensive interventions. However pulmonary rehabilitation (PR) is an available therapeutic option with good evidence of benefit for patients in terms of quality of life and daily functioning.

The primary objective of the study is to evaluate the effectiveness and cost effectiveness of the addition of a maintenance programme following pulmonary rehabilitation in patients with COPD when compared to standard care.

The secondary objective is to identify baseline characteristics that will predict improvement in pulmonary rehabilitation programmes and adherence to maintenance strategies. By measuring a series of demographic, clinical, physiological, psychological and biochemical parameters the researchers hope to be able to predict those patients who are likely to receive the greatest benefit from pulmonary rehabilitation.

An additional objective will be to prepare a detailed maintenance programme manual. This will be available to other centres providing pulmonary rehabilitation at the conclusion of the study


Options:
A: Intervention Type: DEVICE; Name: Noninvasive positive pressure ventilation; Assigned to Arm(s): N/A
B: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo, Drug: Plus placebo laxative, Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine Sulfate (0, 0, 8 mg); Type: EXPERIMENTAL; Interventions: Drug: Placebo, Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Drug: Plus placebo laxative, Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (0, 8, 8 mg); Type: EXPERIMENTAL; Interventions: Drug: Placebo, Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Drug: Plus placebo laxative, Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (0, 8, 16 mg); Type: EXPERIMENTAL; Interventions: Drug: Placebo, Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Drug: Plus placebo laxative, Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (8, 8, 8 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (8, 8, 16 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (8, 16, 16 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (8, 16, 24 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (16, 16, 16 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (16, 16, 24 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (16, 24, 24 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Arm Label: Morphine sulfate (16, 24, 32 mg); Type: EXPERIMENTAL; Interventions: Drug: Morphine Sulfate, Drug: Plus laxative (Docusate with senna), Device: FitBit charge HR (Accelerometer) | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Morphine Sulfate (0, 0, 8 mg), Morphine sulfate (0, 8, 16 mg), Morphine sulfate (0, 8, 8 mg), Placebo | Intervention Type: DRUG; Name: Morphine Sulfate; Assigned to Arm(s): Morphine Sulfate (0, 0, 8 mg), Morphine sulfate (0, 8, 16 mg), Morphine sulfate (0, 8, 8 mg), Morphine sulfate (16, 16, 16 mg), Morphine sulfate (16, 16, 24 mg), Morphine sulfate (16, 24, 24 mg), Morphine sulfate (16, 24, 32 mg), Morphine sulfate (8, 16, 16 mg), Morphine sulfate (8, 16, 24 mg), Morphine sulfate (8, 8, 16 mg), Morphine sulfate (8, 8, 8 mg) | Intervention Type: DRUG; Name: Plus laxative (Docusate with senna); Assigned to Arm(s): Morphine Sulfate (0, 0, 8 mg), Morphine sulfate (0, 8, 16 mg), Morphine sulfate (0, 8, 8 mg), Morphine sulfate (16, 16, 16 mg), Morphine sulfate (16, 16, 24 mg), Morphine sulfate (16, 24, 24 mg), Morphine sulfate (16, 24, 32 mg), Morphine sulfate (8, 16, 16 mg), Morphine sulfate (8, 16, 24 mg), Morphine sulfate (8, 8, 16 mg), Morphine sulfate (8, 8, 8 mg) | Intervention Type: DRUG; Name: Plus placebo laxative; Assigned to Arm(s): Morphine Sulfate (0, 0, 8 mg), Morphine sulfate (0, 8, 16 mg), Morphine sulfate (0, 8, 8 mg), Placebo | Intervention Type: DEVICE; Name: FitBit charge HR (Accelerometer); Assigned to Arm(s): Morphine Sulfate (0, 0, 8 mg), Morphine sulfate (0, 8, 16 mg), Morphine sulfate (0, 8, 8 mg), Morphine sulfate (16, 16, 16 mg), Morphine sulfate (16, 16, 24 mg), Morphine sulfate (16, 24, 24 mg), Morphine sulfate (16, 24, 32 mg), Morphine sulfate (8, 16, 16 mg), Morphine sulfate (8, 16, 24 mg), Morphine sulfate (8, 8, 16 mg), Morphine sulfate (8, 8, 8 mg), Placebo
C: Arm Label: Pulmonary Rehabilitation Group; Type: EXPERIMENTAL; Interventions: Behavioral: Pulmonary Intervention | Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Pulmonary Intervention; Assigned to Arm(s): Pulmonary Rehabilitation Group
D: Arm Label: Tool + Self-management Support Program; Type: EXPERIMENTAL; Interventions: Device: Tool, Behavioral: Self-management Support Program | Arm Label: Self- management Support Program; Type: EXPERIMENTAL; Interventions: Behavioral: Self-management Support Program | Arm Label: Care as usual; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: Tool; Assigned to Arm(s): Tool + Self-management Support Program | Intervention Type: BEHAVIORAL; Name: Self-management Support Program; Assigned to Arm(s): Self- management Support Program, Tool + Self-management Support Program

Answer: C