TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Acute Hemodynamic Effects of Sildenafil in Patients With Severe Aortic Stenosis
Brief Summary: Pulmonary hypertension is common in patients with aortic stenosis and is associated with worse operative and long-term outcomes. Sildenafil has been shown to reduce pulmonary artery pressure and improve exercise performance in patients with left-sided heart failure, but this has not been tested in patients with aortic stenosis. We hypothesize that Sildenafil will produce a clinically significant decrease in pulmonary artery pressure in patients with severe aortic stenosis. The dose of Sildenafil that produces a significant decrease in pulmonary artery pressure will be safe and well tolerated in patients with and without a depressed ejection fraction.


Options:
A: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: Sildenafil citrate | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Sildenafil citrate; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): 2
B: Arm Label: Sildenafil; Type: ACTIVE_COMPARATOR; Interventions: Drug: Sildenafil Citrate | Arm Label: Placebo / Sildanafil; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Intervention Type: DRUG; Name: Sildenafil Citrate; Assigned to Arm(s): Sildenafil | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Placebo / Sildanafil
C: Arm Label: Sildenafil 40mg or 80mg; Type: EXPERIMENTAL; Interventions: Drug: Sildenafil | Intervention Type: DRUG; Name: Sildenafil; Assigned to Arm(s): Sildenafil 40mg or 80mg
D: Arm Label: Sildenafil; Type: EXPERIMENTAL; Interventions: Drug: sildenafil | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: sildenafil | Intervention Type: DRUG; Name: sildenafil; Assigned to Arm(s): Placebo, Sildenafil

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Efficacy and Learning Skill After OROS Methylphenidate Treatment in Adolescents With Attention-Deficit/Hyperactivity Disorder: A 12-week, Multi-center, Open-label Study
Brief Summary: The purpose of this study is to evaluate the efficacy, tolerability and effects of Osmotic Release Oral System (OROS) methylphenidate hydrochloride (HCl) on learning skill changes in Korean participants with Attention-Deficit Hyperactivity Disorder (ADHD).


Options:
A: Arm Label: OROS Methylphenidate HCl; Type: EXPERIMENTAL; Interventions: Drug: OROS Methylphenidate HCl | Intervention Type: DRUG; Name: OROS Methylphenidate HCl; Assigned to Arm(s): OROS Methylphenidate HCl
B: Arm Label: A; Type: N/A; Interventions: Drug: Atomoxetine | Arm Label: B; Type: N/A; Interventions: Drug: stimulants (any approved ADHD medication) | Intervention Type: DRUG; Name: Atomoxetine; Assigned to Arm(s): A | Intervention Type: DRUG; Name: stimulants (any approved ADHD medication); Assigned to Arm(s): B
C: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: Methylphenidate Transdermal System | Intervention Type: DRUG; Name: Methylphenidate Transdermal System; Assigned to Arm(s): 1
D: Arm Label: Methylphenidate transdermal system; Type: EXPERIMENTAL; Interventions: Drug: Methylphenidate Transdermal System | Intervention Type: DRUG; Name: Methylphenidate Transdermal System; Assigned to Arm(s): Methylphenidate transdermal system

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Hemostatic Effects of Ulinastatin and Tranexamic Acid in Cardiac Surgery With Cardiopulmonary Bypass: A Pilot Study
Brief Summary: Antifibrinolytic drugs are used to decrease perioperative bleeding and allogeneic transfusions. The extensively studied antifibrinolytic drug aprotinin is efficacious but expensive, and has been proved to link to higher risks of serious side effects including renal problems, myocardial events, and strokes in patients undergoing CABG. After the secession of aprotinin in 2007, a marked increase of blood loss and transfusions in cardiac surgery took place. An effective and secure hemostatic agent is badly needed. Ulinastatin, urinary trypsin inhibitor(UTI), is a secreted Kunitz-type protease inhibitor with a wide inhibition spectrum, including plasmin. Limited studies offered clues to its antifibrinolytic effect. Tranexamic acid has been applied for years with convinced efficacy and safety. The objective of the study is to evaluate the hemostatic effect of ulinastatin and tranexamic acid in cardiac surgery.


Options:
A: Arm Label: Ulinastatin; Type: EXPERIMENTAL; Interventions: Drug: Ulinastatin | Arm Label: Tranexamic Acid; Type: EXPERIMENTAL; Interventions: Drug: Tranexamic Acid | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Saline Solution | Intervention Type: DRUG; Name: Ulinastatin; Assigned to Arm(s): Ulinastatin | Intervention Type: DRUG; Name: Tranexamic Acid; Assigned to Arm(s): Tranexamic Acid | Intervention Type: DRUG; Name: Saline Solution; Assigned to Arm(s): Placebo
B: Arm Label: HOE 140; Type: EXPERIMENTAL; Interventions: Drug: HOE 140 | Arm Label: Aminocaproic Acid; Type: ACTIVE_COMPARATOR; Interventions: Drug: Aminocaproic Acid | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: HOE 140; Assigned to Arm(s): HOE 140 | Intervention Type: DRUG; Name: Aminocaproic Acid; Assigned to Arm(s): Aminocaproic Acid | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
C: Arm Label: Interventional group; Type: EXPERIMENTAL; Interventions: Device: hemoadsorber for removal of cytokines | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: hemoadsorber for removal of cytokines; Assigned to Arm(s): Interventional group
D: Arm Label: Off-pump coronary artery bypass graft; Type: N/A; Interventions: Procedure: Off-pump coronary artery bypass graft | Arm Label: Mini extracorporeal circulation bypass; Type: N/A; Interventions: Procedure: Mini extracorporeal circulation bypass | Intervention Type: PROCEDURE; Name: Off-pump coronary artery bypass graft; Assigned to Arm(s): Off-pump coronary artery bypass graft | Intervention Type: PROCEDURE; Name: Mini extracorporeal circulation bypass; Assigned to Arm(s): Mini extracorporeal circulation bypass

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized, Double-Blind, Placebo-Controlled Study to Explore the Efficacy, Safety, and Tolerability of JNJ-42160443 in Subjects With Interstitial Cystitis/ Painful Bladder Syndrome
Brief Summary: The purpose of this study is to evaluate the analgesic efficacy, safety, and tolerability of JNJ-42160443 compared to placebo in patients with moderate to severe, chronic bladder pain from interstitial cystitis and/or painful bladder syndrome.


Options:
A: Arm Label: AQX-1125; Type: EXPERIMENTAL; Interventions: Drug: AQX-1125 | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: AQX-1125; Assigned to Arm(s): AQX-1125 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
B: Arm Label: Botulinum toxin A; Type: EXPERIMENTAL; Interventions: Drug: Botulinum toxin A | Arm Label: Control arm-Normal saline instillation; Type: PLACEBO_COMPARATOR; Interventions: Drug: Normal saline instillation | Intervention Type: DRUG; Name: Botulinum toxin A; Assigned to Arm(s): Botulinum toxin A | Intervention Type: DRUG; Name: Normal saline instillation; Assigned to Arm(s): Control arm-Normal saline instillation
C: Arm Label: JNJ-42160443; Type: EXPERIMENTAL; Interventions: Drug: JNJ-42160443 | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo | Intervention Type: DRUG; Name: JNJ-42160443; Assigned to Arm(s): JNJ-42160443
D: Arm Label: Botulinum toxin; Type: ACTIVE_COMPARATOR; Interventions: Procedure: intratrigonal injection of botulinum toxin | Arm Label: cystoscopy with hydrodistension; Type: SHAM_COMPARATOR; Interventions: Procedure: cystoscopy | Intervention Type: PROCEDURE; Name: intratrigonal injection of botulinum toxin; Assigned to Arm(s): Botulinum toxin | Intervention Type: PROCEDURE; Name: cystoscopy; Assigned to Arm(s): cystoscopy with hydrodistension

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effect of Intravenous Bolus Infusion of Erythromycin Prior to Endoscopy in Patients Presenting With Variceal Bleeding: A Prospective, Randomized, Double- Blind ,Placebo Controlled, Trial
Brief Summary: Objectives:

Blood in stomach \& oesophagus in patients with variceal bleeding often obscures the endoscopic view \& makes endoscopic intervention difficult to perform. Erythromycin, a motilin agonist induces gastric emptying. The aim of this study was to assess the effect of Erythromycin on endoscopic visibility and its outcome.


Options:
A: Arm Label: Experimental group; Type: EXPERIMENTAL; Interventions: Drug: Terlipressin | Arm Label: Control group; Type: ACTIVE_COMPARATOR; Interventions: Drug: Octreotide | Intervention Type: DRUG; Name: Terlipressin; Assigned to Arm(s): Experimental group | Intervention Type: DRUG; Name: Octreotide; Assigned to Arm(s): Control group
B: Arm Label: EVL plus Somatostatin; Type: EXPERIMENTAL; Interventions: Drug: Somatostatin | Arm Label: EVL plus Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Somatostatin; Assigned to Arm(s): EVL plus Somatostatin | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): EVL plus Placebo
C: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Emergency portacaval shunt | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Other: Emergency TIPS | Intervention Type: PROCEDURE; Name: Emergency portacaval shunt; Assigned to Arm(s): A | Intervention Type: OTHER; Name: Emergency TIPS; Assigned to Arm(s): B
D: Arm Label: Erythromycin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Erythromycin | Arm Label: Placebo Group endoscopic therapy; Type: NO_INTERVENTION; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Erythromycin; Assigned to Arm(s): Erythromycin | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo Group endoscopic therapy

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effect of Intravenous Bolus Infusion of Erythromycin Prior to Endoscopy in Patients Presenting With Variceal Bleeding: A Prospective, Randomized, Double- Blind ,Placebo Controlled, Trial
Brief Summary: Objectives:

Blood in stomach \& oesophagus in patients with variceal bleeding often obscures the endoscopic view \& makes endoscopic intervention difficult to perform. Erythromycin, a motilin agonist induces gastric emptying. The aim of this study was to assess the effect of Erythromycin on endoscopic visibility and its outcome.


Options:
A: Intervention Type: DRUG; Name: Macrolides (azithromycin or clarithromycin); Assigned to Arm(s): N/A
B: Arm Label: Erythromycin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Erythromycin | Arm Label: Placebo Group endoscopic therapy; Type: NO_INTERVENTION; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Erythromycin; Assigned to Arm(s): Erythromycin | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo Group endoscopic therapy
C: Arm Label: Azythromycin (APRIL) and Prednisolone (OCELOT); Type: EXPERIMENTAL; Interventions: Drug: Azithromycin, Drug: Prednisolone | Arm Label: Azythromycin (APRIL) and Placebo (OCELOT); Type: EXPERIMENTAL; Interventions: Drug: Azithromycin, Drug: Placebo Prednisolone | Arm Label: Placebo (APRIL) and Prednisolone (OCELOT); Type: EXPERIMENTAL; Interventions: Drug: Prednisolone, Other: Placebo Azithromycin | Arm Label: Placebo (APRIL) and Placebo (OCELOT); Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo Azithromycin, Drug: Placebo Prednisolone | Intervention Type: DRUG; Name: Azithromycin; Assigned to Arm(s): Azythromycin (APRIL) and Placebo (OCELOT), Azythromycin (APRIL) and Prednisolone (OCELOT) | Intervention Type: DRUG; Name: Prednisolone; Assigned to Arm(s): Azythromycin (APRIL) and Prednisolone (OCELOT), Placebo (APRIL) and Prednisolone (OCELOT) | Intervention Type: OTHER; Name: Placebo Azithromycin; Assigned to Arm(s): Placebo (APRIL) and Placebo (OCELOT), Placebo (APRIL) and Prednisolone (OCELOT) | Intervention Type: DRUG; Name: Placebo Prednisolone; Assigned to Arm(s): Azythromycin (APRIL) and Placebo (OCELOT), Placebo (APRIL) and Placebo (OCELOT)
D: Arm Label: Azithromycin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Azithromycin | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Azithromycin; Assigned to Arm(s): Azithromycin | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effect of Intravenous Bolus Infusion of Erythromycin Prior to Endoscopy in Patients Presenting With Variceal Bleeding: A Prospective, Randomized, Double- Blind ,Placebo Controlled, Trial
Brief Summary: Objectives:

Blood in stomach \& oesophagus in patients with variceal bleeding often obscures the endoscopic view \& makes endoscopic intervention difficult to perform. Erythromycin, a motilin agonist induces gastric emptying. The aim of this study was to assess the effect of Erythromycin on endoscopic visibility and its outcome.


Options:
A: Arm Label: Over-the-scope Clips; Type: EXPERIMENTAL; Interventions: Device: Over-the-scope Clips | Arm Label: standard treatment; Type: ACTIVE_COMPARATOR; Interventions: Device: Hemo-clipping, Device: thermo-coagulation, Drug: Epinephrine | Intervention Type: DEVICE; Name: Over-the-scope Clips; Assigned to Arm(s): Over-the-scope Clips | Intervention Type: DEVICE; Name: Hemo-clipping; Assigned to Arm(s): standard treatment | Intervention Type: DEVICE; Name: thermo-coagulation; Assigned to Arm(s): standard treatment | Intervention Type: DRUG; Name: Epinephrine; Assigned to Arm(s): standard treatment
B: Arm Label: TC-325; Type: EXPERIMENTAL; Interventions: Device: Endoscopic Application of a Hemostatic Powder TC-325 | Arm Label: standard treatment; Type: ACTIVE_COMPARATOR; Interventions: Device: Hemo-clipping, Drug: Epinephrine, Device: thermo-coagulation | Intervention Type: DEVICE; Name: Endoscopic Application of a Hemostatic Powder TC-325; Assigned to Arm(s): TC-325 | Intervention Type: DEVICE; Name: Hemo-clipping; Assigned to Arm(s): standard treatment | Intervention Type: DRUG; Name: Epinephrine; Assigned to Arm(s): standard treatment | Intervention Type: DEVICE; Name: thermo-coagulation; Assigned to Arm(s): standard treatment
C: Arm Label: Erythromycin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Erythromycin | Arm Label: Placebo Group endoscopic therapy; Type: NO_INTERVENTION; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Erythromycin; Assigned to Arm(s): Erythromycin | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo Group endoscopic therapy
D: Arm Label: Urgent endoscopy; Type: ACTIVE_COMPARATOR; Interventions: Other: Urgent endoscopy | Arm Label: Early endoscopy; Type: PLACEBO_COMPARATOR; Interventions: Other: Early endoscopy | Intervention Type: OTHER; Name: Urgent endoscopy; Assigned to Arm(s): Urgent endoscopy | Intervention Type: OTHER; Name: Early endoscopy; Assigned to Arm(s): Early endoscopy

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Study of the Benefit of Exercise and Aminoacid Supplements in Cirrhotic Patients
Brief Summary: This is a pilot study including 20 cirrhotic patients that will be randomized to receive during 3 months leucine vs leucine plus a programme of physical exercise specially designed for cirrhotic patients. The hypothesis is that physical exercise in cirrhotic patients could increase muscle mass (and therefore glutamine synthetase activity leading to a higher blood ammonium clearance) and quality of life. Safety of physical exercise in cirrhotic patients will be strictly assessed.


Options:
A: Arm Label: Exercise + Leucine; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Leucine supplements | Arm Label: Leucine without exercise; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Leucine supplements | Intervention Type: DIETARY_SUPPLEMENT; Name: Leucine supplements; Assigned to Arm(s): Exercise + Leucine, Leucine without exercise
B: Arm Label: Home based aerobic exercise; Type: EXPERIMENTAL; Interventions: Behavioral: Home based Aerobic exercise training | Arm Label: Usual Care group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Home based Aerobic exercise training; Assigned to Arm(s): Home based aerobic exercise
C: Arm Label: 1; Type: N/A; Interventions: N/A | Arm Label: 2; Type: N/A; Interventions: N/A
D: Arm Label: Physical training - No encephalopathy; Type: EXPERIMENTAL; Interventions: Other: Physical training, Other: Diet intervention | Arm Label: Control - No encephalopathy; Type: ACTIVE_COMPARATOR; Interventions: Other: Diet intervention | Arm Label: Physical training - Early encephalopathy; Type: EXPERIMENTAL; Interventions: Other: Physical training, Other: Diet intervention | Arm Label: Control - Early encephalopathy; Type: ACTIVE_COMPARATOR; Interventions: Other: Diet intervention | Intervention Type: OTHER; Name: Physical training; Assigned to Arm(s): Physical training - Early encephalopathy, Physical training - No encephalopathy | Intervention Type: OTHER; Name: Diet intervention; Assigned to Arm(s): Control - Early encephalopathy, Control - No encephalopathy, Physical training - Early encephalopathy, Physical training - No encephalopathy

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Community-Academic Partnership to Improve Asthma Management in Latino Children
Brief Summary: This study compares an asthma self-management intervention, delivered to the family and tailored to their needs and cultural beliefs, to standard asthma education in high-risk Puerto Rican children in elementary school. The primary outcomes are asthma medication adherence and trigger reduction.


Options:
A: Intervention Type: DEVICE; Name: electronic medication monitoring system; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: parent-adolescent communication and problem-solving skills; Assigned to Arm(s): N/A
B: Arm Label: community health worker; Type: EXPERIMENTAL; Interventions: Behavioral: community health worker | Arm Label: mailed information; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: mailed information | Intervention Type: BEHAVIORAL; Name: community health worker; Assigned to Arm(s): community health worker | Intervention Type: BEHAVIORAL; Name: mailed information; Assigned to Arm(s): mailed information
C: Arm Label: mailed information; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: mailed information | Arm Label: community health worker; Type: EXPERIMENTAL; Interventions: Behavioral: community health worker | Intervention Type: BEHAVIORAL; Name: community health worker; Assigned to Arm(s): community health worker | Intervention Type: BEHAVIORAL; Name: mailed information; Assigned to Arm(s): mailed information
D: Arm Label: Nurse group; Type: EXPERIMENTAL; Interventions: Behavioral: Self management education | Arm Label: Lay educator group; Type: EXPERIMENTAL; Interventions: Behavioral: Self management education | Intervention Type: BEHAVIORAL; Name: Self management education; Assigned to Arm(s): Lay educator group, Nurse group

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Community-Academic Partnership to Improve Asthma Management in Latino Children
Brief Summary: This study compares an asthma self-management intervention, delivered to the family and tailored to their needs and cultural beliefs, to standard asthma education in high-risk Puerto Rican children in elementary school. The primary outcomes are asthma medication adherence and trigger reduction.


Options:
A: Arm Label: community health worker; Type: EXPERIMENTAL; Interventions: Behavioral: community health worker | Arm Label: mailed information; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: mailed information | Intervention Type: BEHAVIORAL; Name: community health worker; Assigned to Arm(s): community health worker | Intervention Type: BEHAVIORAL; Name: mailed information; Assigned to Arm(s): mailed information
B: Arm Label: Interventional group: Period 2; Type: EXPERIMENTAL; Interventions: Drug: salmeterol/fluticasone propionate 50/250 µg + 3 training sessions of compliance enhancement training | Arm Label: Control group: Period 2; Type: ACTIVE_COMPARATOR; Interventions: Drug: salmeterol/fluticasone propionate 50/250 µg | Arm Label: Subjects receiving salmeterol/fluticasone propionate: Period 1; Type: EXPERIMENTAL; Interventions: Drug: salmeterol/fluticasone propionate 50/250 µg | Intervention Type: DRUG; Name: salmeterol/fluticasone propionate 50/250 µg + 3 training sessions of compliance enhancement training; Assigned to Arm(s): Interventional group: Period 2 | Intervention Type: DRUG; Name: salmeterol/fluticasone propionate 50/250 µg; Assigned to Arm(s): Control group: Period 2, Subjects receiving salmeterol/fluticasone propionate: Period 1
C: Arm Label: mailed information; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: mailed information | Arm Label: community health worker; Type: EXPERIMENTAL; Interventions: Behavioral: community health worker | Intervention Type: BEHAVIORAL; Name: community health worker; Assigned to Arm(s): community health worker | Intervention Type: BEHAVIORAL; Name: mailed information; Assigned to Arm(s): mailed information
D: Arm Label: Active Feedback; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Active Feedback | Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Active Feedback | Intervention Type: BEHAVIORAL; Name: Active Feedback; Assigned to Arm(s): Active Feedback, Control

Answer: C