Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Effects of Supplementing Glutamine on the Gastric Emptying Time of a Preoperative Metabolic Conditioning Drink in Healthy Volunteers: a Randomized Crossover Pilot Study
Brief Summary: Surgical patients are usually starved for 8 hours before operation in order to ensure the stomach is empty and thus reduce the chances of vomiting during the anaesthetic. Recent studies have shown that this period of starvation is harmful as it 'weakens' the body before operation. To avoid the harmful effects of starvation, patients are now given carbohydrate (sugar-containing) drinks 2 to 4 hours before surgery. These drinks have been shown to make patients feel better, reduce sickness after the anaesthetic/surgery and result in a quicker recovery from operation. The optimum time of giving these drinks to patients before operation is unknown. Previous studies have shown that the drinks empty from the stomach within 2 - 4 hours depending on their ingredients. The investigators would like to study the effects of adding protein and fat to these drinks on how quickly the drinks empty from the stomach. This study will investigate the hormone responses of the body following intake of 3 different drinks in order to determine the mechanisms that underlie the control of stomach emptying. This information will also allow us to improve the design of these drinks and this could help patients who undergo surgery who receive them.


Options:
A: Arm Label: Test; Type: EXPERIMENTAL; Interventions: Dietary Supplement: PreOP Booster (oral nutritional supplement, food for special medical purposes) | Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: PreOP Booster (oral nutritional supplement, food for special medical purposes) | Intervention Type: DIETARY_SUPPLEMENT; Name: PreOP Booster (oral nutritional supplement, food for special medical purposes); Assigned to Arm(s): Control, Test
B: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Other: Standard ERAS group | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Drug: Post operative laxation (Magnesium Oxide) | Arm Label: 3; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Preoperative metabolic conditioning postoperative nutritional supplementation | Arm Label: 4; Type: EXPERIMENTAL; Interventions: Drug: Post operative laxation (Magnesium Oxide), Dietary Supplement: Preoperative metabolic conditioning postoperative nutritional supplementation | Intervention Type: DRUG; Name: Post operative laxation (Magnesium Oxide); Assigned to Arm(s): 2, 4 | Intervention Type: DIETARY_SUPPLEMENT; Name: Preoperative metabolic conditioning postoperative nutritional supplementation; Assigned to Arm(s): 3, 4 | Intervention Type: OTHER; Name: Standard ERAS group; Assigned to Arm(s): 1
C: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Other: Intravenous nutrition with glucose and amino acids | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Other: Intravenous nutrition with glucose and amino acids. | Intervention Type: OTHER; Name: Intravenous nutrition with glucose and amino acids; Assigned to Arm(s): 1 | Intervention Type: OTHER; Name: Intravenous nutrition with glucose and amino acids.; Assigned to Arm(s): 2
D: Arm Label: Nutricia PreOp + Lipid; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Nutricia PreOp nutritional supplement, Dietary Supplement: Lipid | Arm Label: Nutrica PreOP + Glutamine; Type: ACTIVE_COMPARATOR; Interventions: Dietary Supplement: Nutricia PreOp nutritional supplement, Dietary Supplement: Glutamine | Arm Label: Nutricia PreOP; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Nutricia PreOp nutritional supplement | Intervention Type: DIETARY_SUPPLEMENT; Name: Nutricia PreOp nutritional supplement; Assigned to Arm(s): Nutrica PreOP + Glutamine, Nutricia PreOP, Nutricia PreOp + Lipid | Intervention Type: DIETARY_SUPPLEMENT; Name: Lipid; Assigned to Arm(s): Nutricia PreOp + Lipid | Intervention Type: DIETARY_SUPPLEMENT; Name: Glutamine; Assigned to Arm(s): Nutrica PreOP + Glutamine

Answer: D