Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Maternal Oral Vitamin D Supplementation Via Daily or Monthly Regimens and the Effect on Levels of Vitamin D in Human Milk and Infant Serum
Brief Summary: Adequate vitamin D is essential for proper infant growth and development. However, human milk is low in vitamin D, and most infants do not receive recommended supplementation. Our aim is to assess the feasibility of providing adequate vitamin D to breastfed infants through maternal vitamin D supplementation. Forty non-pregnant, lactating women at least 18 years of age with exclusively breastfed infants between the ages of 1 and 6 months will be randomized to receive oral vitamin D as either 5,000 IU daily for 28 days or 150,000 IU as a single dose. Maternal serum calcium, phosphorus, vitamin D and 25(OH)D; maternal urinary calcium; maternal milk vitamin D and 25(OH)D will be measured on days 0, 1, 3, 7, 14, and 28 of the study; and infant serum vitamin D and 25(OH)D will be measured on days 0 and 28.


Options:
A: Arm Label: Group A; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: Placebo | Arm Label: Group B; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Vitamin D3 | Arm Label: Group C; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Vitamin D3 | Arm Label: Group D; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Vitamin D3 | Arm Label: Group E; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Vitamin D3 | Intervention Type: DIETARY_SUPPLEMENT; Name: Vitamin D3; Assigned to Arm(s): Group B, Group C, Group D, Group E | Intervention Type: DIETARY_SUPPLEMENT; Name: Placebo; Assigned to Arm(s): Group A
B: Arm Label: Vitamin D 150,000 units once; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Vitamin D3 | Arm Label: Vitamin D 5000 units daily; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Vitamin D3 | Intervention Type: DIETARY_SUPPLEMENT; Name: Vitamin D3; Assigned to Arm(s): Vitamin D 150,000 units once | Intervention Type: DIETARY_SUPPLEMENT; Name: Vitamin D3; Assigned to Arm(s): Vitamin D 5000 units daily
C: Arm Label: choecalciferol; Type: EXPERIMENTAL; Interventions: Dietary Supplement: cholecalciferol | Arm Label: placebo; Type: PLACEBO_COMPARATOR; Interventions: Dietary Supplement: placebo | Intervention Type: DIETARY_SUPPLEMENT; Name: cholecalciferol; Assigned to Arm(s): choecalciferol | Intervention Type: DIETARY_SUPPLEMENT; Name: placebo; Assigned to Arm(s): placebo
D: Arm Label: Control 400 IU vitamin D3; Type: ACTIVE_COMPARATOR; Interventions: Drug: 400 IU Vitamin D3 (cholecalciferol) | Arm Label: 2400 IU vitamin D3 (cholecalciferol); Type: EXPERIMENTAL; Interventions: Drug: 2400 IU Vitamin D3 (cholecalciferol) | Arm Label: 6400 IU vitamin D3 (cholecalciferol); Type: EXPERIMENTAL; Interventions: Drug: 6400 IU Vitamin D3 (cholecalciferol) | Intervention Type: DRUG; Name: 400 IU Vitamin D3 (cholecalciferol); Assigned to Arm(s): Control 400 IU vitamin D3 | Intervention Type: DRUG; Name: 2400 IU Vitamin D3 (cholecalciferol); Assigned to Arm(s): 2400 IU vitamin D3 (cholecalciferol) | Intervention Type: DRUG; Name: 6400 IU Vitamin D3 (cholecalciferol); Assigned to Arm(s): 6400 IU vitamin D3 (cholecalciferol)

Answer: B