TrialPanorama/Dataset huggingface dataset:
Please select the outcome measures that correspond to the clinical trial below.
Title: Postoperative Myocardial Injury and Non-cardiac Complications After Major Abdominal Surgery in Patients at Risk for Coronary Artery Disease
Brief Summary: To determine whether perioperative myocardial injury is associated with adverse outcome in patients scheduled for major abdominal surgery.


Options:
A: quality of life (1 year); functional health (1 year); falls (1 year); cognition (1 year); emotional health (1 year); mental health (1 year); physical health (1 year); pain (1 year); intraoperative awareness (30-90 days); all-cause mortality (1 year); surgical wound infection (1 year); nerve injury (30-90 days); stroke (1 year); delirium (30-90days); Stomach Ulcer (30-90 days); Gastrointestinal Bleed (30-90 days); Pneumonia (1 year); Respiratory Failure (1 year); Respiratory Arrest (1 year); Pulmonary Embolism (1 year); Deep Vein Thrombosis (1 year); Angina (1 year); Atrial Fibrillation (1 year); Congestive Heart Failure (1 year); Cardiac Arrest (1 year); Heart Attack (1 year)
B: Change from baseline endothelial function (reactive hyperemia index) at 4 days postoperatively (baseline before operation, 4 hours postoperatively and daily assessments day 1-4 after surgery.)
C: Deaths in one year after non-cardiac surgery in patients with and without PMI (1 year)
D: Postoperative myocardial injury (7 days)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Assessment of Patterns of Patient-reported Outcomes in Adults With Congenital Heart Disease - International Study
Brief Summary: The purpose of this study is to examine the differences in perceived health, psychosocial functioning, behavioral outcomes and quality of life of adults with congenital heart disease who are living in different areas of the world, and how these differences can be understood (e.g., differences in sense of coherence or illness perceptions).


Options:
A: Quality of life score (PedsQL, 24 items), range score from 0 to 100, higher score indicating better quality of life. (follow up of patients over 12 months)
B: Patient-reported health status (EuroQol-5D) (Baseline); Patient-reported psychosocial functioning (Hospital Anxiety and Depression Scale) (Baseline); Patient-reported behavioral outcomes (Health Behavior Scale - Congenital Heart Disease) (Baseline); Patient-reported quality of life (Linear Analog Scale Quality of Life;Satisfaction with Life Scale) (Baseline)
C: Maximal inspiratory pressure in kilopascal (12 weeks)
D: Quality of Life questionnaire (one day)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Mindfulness-Based Stress Management Program and Omega-3 Fatty Acids to Maintain Healthy Mental State in Hospital Nurses: Multi-Center Factorial-Design Randomized Controlled Trial Happy Nurse Project
Brief Summary: The study is to explore the effectiveness of omega-3 fatty acids and mindfulness-based stress management program to maintain healthy mental state in hospital nurses. The participants will be junior nurses who work in inpatient wards and are not clinically depressed. The participants will be randomly allocated to four intervention arms: 1) Mindfulness-based stress management program plus omega-3 fatty acids pills ; 2) Mindfulness-based stress management program plus placebo pills; 3) Psychoeducation leaflet plus omega-3 fatty acids pills; and 4) Psychoeducation leaflet plus placebo pills. Thirty participants will be allocated to each arm. These interventions will terminate until three months from registration for each participant.

Information about depression and anxiety symptoms (primary outcome), insomnia, burnout, presenteeism, quality of life, sick leave, consultation about mental state of herself, and oxidative stress will be collected at 3 months, 6 months (primary time point) and 12 months from registration for each participant.


Options:
A: Professional identity (We will measure the score of professional identity before intervention and immediately after intervention.); Career self-efficacy (We will measure the score of career self-efficacy before intervention and immediately after intervention.)
B: Perceived Stress Scale (At the end of five days retreat); Self-compassion (At the end of five days retreat)
C: Blindly-rated depression and anxiety severity: Hospital Anxiety and Depression Scale (HADS) (26 weeks)
D: Daily Depression (Change in daily depression assessed daily for seven days during week 2 and week 16 of the study.); Depression I (Change in depression over 4-month period.); Depression II (Change in depression over 4-month period.); Daily Social Connection (Change in daily social connection assessed daily for seven days during week 2 and week 16 of the study.); Daily Belonging (Change in loneliness over 4-month period.); Loneliness (Change in loneliness over 4-month period.)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Mindfulness-Based Stress Management Program and Omega-3 Fatty Acids to Maintain Healthy Mental State in Hospital Nurses: Multi-Center Factorial-Design Randomized Controlled Trial Happy Nurse Project
Brief Summary: The study is to explore the effectiveness of omega-3 fatty acids and mindfulness-based stress management program to maintain healthy mental state in hospital nurses. The participants will be junior nurses who work in inpatient wards and are not clinically depressed. The participants will be randomly allocated to four intervention arms: 1) Mindfulness-based stress management program plus omega-3 fatty acids pills ; 2) Mindfulness-based stress management program plus placebo pills; 3) Psychoeducation leaflet plus omega-3 fatty acids pills; and 4) Psychoeducation leaflet plus placebo pills. Thirty participants will be allocated to each arm. These interventions will terminate until three months from registration for each participant.

Information about depression and anxiety symptoms (primary outcome), insomnia, burnout, presenteeism, quality of life, sick leave, consultation about mental state of herself, and oxidative stress will be collected at 3 months, 6 months (primary time point) and 12 months from registration for each participant.


Options:
A: Blindly-rated depression and anxiety severity: Hospital Anxiety and Depression Scale (HADS) (26 weeks)
B: Degree of occupational stress (Change from baseline at 4 weeks (EG4) or 8 weeks (EG8 or CG)); Degree of occupational stress (Change from baseline at 4 weeks (EG4) or 8 weeks (EG8 or CG)); Degree of burnout (Change from baseline at 4 weeks (EG4) or 8 weeks (EG8 or CG)); Degree of Self-Compassion (Change from baseline at 4 weeks (EG4) or 8 weeks (EG8 or CG))
C: Pre-/post-intervention changes in mRNA transcript abundance across the entire transcriptome of circulating immune cells in the intervention group relative to the control group. (6 weeks); Pre-/post-intervention changes in IL-6 (6 weeks); Pre-/post-intervention changes in IL-8 (6 weeks); Pre-/post-intervention changes in IL-10 (6 weeks); Pre-/post-intervention changes in TNF-α (6 weeks); Pre-/post-intervention changes in IFN-γ (6 weeks); Pre-/post-intervention changes in peripheral blood mononuclear cell (PBMC) telomerase activity (6 weeks)
D: Change on Perceived Stress Scale 14 (PSS-14) (Change from baseline on PSS-14 (3 or 6 weeks depending on the study condition)); Change on Perceived Stress Scale 14 (PSS-14) (Change from baseline on PSS-14 (6 months)); Change on Perceived Stress Scale 14 (PSS-14) (Change from baseline on PSS-14 (12 months)); Change on Oldenburg Burnout Inventory (OLBI) (Change from baseline on OLBI (3 or 6 weeks depending on the study condition)); Change on Oldenburg Burnout Inventory (OLBI) (Change from baseline on OLBI (6 months)); Change on Oldenburg Burnout Inventory (OLBI) (Change from baseline on OLBI (12 months))

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Mindfulness-Based Stress Management Program and Omega-3 Fatty Acids to Maintain Healthy Mental State in Hospital Nurses: Multi-Center Factorial-Design Randomized Controlled Trial Happy Nurse Project
Brief Summary: The study is to explore the effectiveness of omega-3 fatty acids and mindfulness-based stress management program to maintain healthy mental state in hospital nurses. The participants will be junior nurses who work in inpatient wards and are not clinically depressed. The participants will be randomly allocated to four intervention arms: 1) Mindfulness-based stress management program plus omega-3 fatty acids pills ; 2) Mindfulness-based stress management program plus placebo pills; 3) Psychoeducation leaflet plus omega-3 fatty acids pills; and 4) Psychoeducation leaflet plus placebo pills. Thirty participants will be allocated to each arm. These interventions will terminate until three months from registration for each participant.

Information about depression and anxiety symptoms (primary outcome), insomnia, burnout, presenteeism, quality of life, sick leave, consultation about mental state of herself, and oxidative stress will be collected at 3 months, 6 months (primary time point) and 12 months from registration for each participant.


Options:
A: Perceived Stress (3 months post-intervention)
B: Rate of participant recruitment (1 year); Rate of retention (1 year); Completeness of data entry (1 year); Cost of interventions (1 year); Unexpected costs (1 year)
C: Resilience - Brief Resilience Scale (BRS) (20 weeks); General Health - General Health Questionnaire (GHQ-12). (20 weeks)
D: Blindly-rated depression and anxiety severity: Hospital Anxiety and Depression Scale (HADS) (26 weeks)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Mindfulness-Based Stress Management Program and Omega-3 Fatty Acids to Maintain Healthy Mental State in Hospital Nurses: Multi-Center Factorial-Design Randomized Controlled Trial Happy Nurse Project
Brief Summary: The study is to explore the effectiveness of omega-3 fatty acids and mindfulness-based stress management program to maintain healthy mental state in hospital nurses. The participants will be junior nurses who work in inpatient wards and are not clinically depressed. The participants will be randomly allocated to four intervention arms: 1) Mindfulness-based stress management program plus omega-3 fatty acids pills ; 2) Mindfulness-based stress management program plus placebo pills; 3) Psychoeducation leaflet plus omega-3 fatty acids pills; and 4) Psychoeducation leaflet plus placebo pills. Thirty participants will be allocated to each arm. These interventions will terminate until three months from registration for each participant.

Information about depression and anxiety symptoms (primary outcome), insomnia, burnout, presenteeism, quality of life, sick leave, consultation about mental state of herself, and oxidative stress will be collected at 3 months, 6 months (primary time point) and 12 months from registration for each participant.


Options:
A: Blindly-rated depression and anxiety severity: Hospital Anxiety and Depression Scale (HADS) (26 weeks)
B: Professional Quality of Life Scale-IV (ProQoL), "change" is being assessed. (Change from Baseline up to 1 year); Perceived Stress Scale, "change" is being assessed. (Change from Baseline up to 1 year); Resilience Scale for Adults, "change" is being assessed. (Change from Baseline up to 1 year)
C: CAPS-5 (Clinician Administered PTSD Scale) (12 months)
D: Suicidal behavior and ideation (Weeks 4, 12, and 24)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Mindfulness-Based Stress Management Program and Omega-3 Fatty Acids to Maintain Healthy Mental State in Hospital Nurses: Multi-Center Factorial-Design Randomized Controlled Trial Happy Nurse Project
Brief Summary: The study is to explore the effectiveness of omega-3 fatty acids and mindfulness-based stress management program to maintain healthy mental state in hospital nurses. The participants will be junior nurses who work in inpatient wards and are not clinically depressed. The participants will be randomly allocated to four intervention arms: 1) Mindfulness-based stress management program plus omega-3 fatty acids pills ; 2) Mindfulness-based stress management program plus placebo pills; 3) Psychoeducation leaflet plus omega-3 fatty acids pills; and 4) Psychoeducation leaflet plus placebo pills. Thirty participants will be allocated to each arm. These interventions will terminate until three months from registration for each participant.

Information about depression and anxiety symptoms (primary outcome), insomnia, burnout, presenteeism, quality of life, sick leave, consultation about mental state of herself, and oxidative stress will be collected at 3 months, 6 months (primary time point) and 12 months from registration for each participant.


Options:
A: Change in Aggression (baseline, post-intervention (week 8), 3-month followup, 6-month followup)
B: Blindly-rated depression and anxiety severity: Hospital Anxiety and Depression Scale (HADS) (26 weeks)
C: Change in Stress (baseline, 8wks (post-intervention),12-month follow-up)
D: Changes in PTSD symptoms(PCL) (Pre-treatment(baseline), after first deployment, 10 days after combat, 4 months after combat); Probable PTSD diagnosis(CAPS) (Four months after combat)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Improving Mental Health Outcomes: Building an Adaptive Implementation
Brief Summary: The overarching goal of this study is to build the most cost-effective adaptive implementation intervention involving a site-level implementation intervention strategy: Replicating Effective Programs (REP), and the augmentation of REP using either External Facilitation or a combination of an External and Internal Facilitation to improve patient outcomes and the uptake of an evidence-based program for mood disorders (Life Goals-LG) in community settings.


Options:
A: Reduction in symptoms of psychosis (6 months)
B: Health-related Quality of Life - Mental Health Component Score (Change from Baseline in Quality of Life at 12-months); Reduced Mood Disorder Symptoms (Change from Baseline in Mood Disorder Symptoms at 12-months)
C: Recovery from Common Mental Disorder (defined by ICD10) (6 months)
D: Change in PTSD Symptom Severity (PDS) (Baseline, 6 months)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Home and Community Management of Fevers/Malaria and Pneumonia in Children Under-five: a Cluster Randomised Controlled Trial of an Integrated Approach in a Rural District of Burkina Faso
Brief Summary: A well-implemented community-based program of early and appropriate treatment of fevers/malaria episodes and pneumonia,will improve child survival as measured by a reduction of the less than five mortality rate.


Options:
A: Number of death in children aged 6 to 59 months (12 months)
B: Appropriateness of treatment (36 months)
C: Number of patients with fever prescribed artemether-lumefantrine for the treatment of malaria in respective study groups (28 days)
D: Percentage of change in number of children under five in intervention area who receive appropriate Integrated Community Case Management Treatment from a Community Health Worker for presumed pneumonia. (March 2013 - November 2014 (8 months)); Percentage of change in number of children under five in intervention area who receive appropriate Integrated Community Case Management Treatment from a Community Health Worker for diarrhea (March 2013 - November 2014 (8 months)); Percentage of change in number of children under five in intervention area who receive Integrated Community Case Management Treatment from a Community Health Worker for fever. (March 2013 - November 2014 (8 months))

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Home and Community Management of Fevers/Malaria and Pneumonia in Children Under-five: a Cluster Randomised Controlled Trial of an Integrated Approach in a Rural District of Burkina Faso
Brief Summary: A well-implemented community-based program of early and appropriate treatment of fevers/malaria episodes and pneumonia,will improve child survival as measured by a reduction of the less than five mortality rate.


Options:
A: Absolute change pre/post intervention (VHV ICCM training) in proportion of U5s receiving (a) antimalarial for fever (b) ORS/Zn for diarrhea (c) Abx for pneumonia (pre- (Dec 2010) post- (Dec 2012) intervention (2 years))
B: Percentage of change in number of children under five in intervention area who receive appropriate Integrated Community Case Management Treatment from a Community Health Worker for presumed pneumonia. (March 2013 - November 2014 (8 months)); Percentage of change in number of children under five in intervention area who receive appropriate Integrated Community Case Management Treatment from a Community Health Worker for diarrhea (March 2013 - November 2014 (8 months)); Percentage of change in number of children under five in intervention area who receive Integrated Community Case Management Treatment from a Community Health Worker for fever. (March 2013 - November 2014 (8 months))
C: Difference in the under-five child mortality rate between the two study arms (36 months)
D: Number of death in children aged 6 to 59 months (12 months)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Home and Community Management of Fevers/Malaria and Pneumonia in Children Under-five: a Cluster Randomised Controlled Trial of an Integrated Approach in a Rural District of Burkina Faso
Brief Summary: A well-implemented community-based program of early and appropriate treatment of fevers/malaria episodes and pneumonia,will improve child survival as measured by a reduction of the less than five mortality rate.


Options:
A: Percentage of change in number of children under five in intervention area who receive appropriate Integrated Community Case Management Treatment from a Community Health Worker for presumed pneumonia. (March 2013 - November 2014 (8 months)); Percentage of change in number of children under five in intervention area who receive appropriate Integrated Community Case Management Treatment from a Community Health Worker for diarrhea (March 2013 - November 2014 (8 months)); Percentage of change in number of children under five in intervention area who receive Integrated Community Case Management Treatment from a Community Health Worker for fever. (March 2013 - November 2014 (8 months))
B: The coverage of the therapeutic nutritional program in the control and intervention health districts (12 months)
C: Brief Psychiatric Rating Scale, Expanded Version (BPRS-E) (12 months post-randomisation (18 months for secondary outcome))
D: Number of death in children aged 6 to 59 months (12 months)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: A Phase III, Open Label, Randomized Study of AZD9291 Versus Platinum-Based Doublet Chemotherapy for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Whose Disease Has Progressed With Previous Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy and Whose Tumours Harbour a T790M Mutation Within the Epidermal Growth Factor Receptor Gene (AURA3).
Brief Summary: A Phase III, Open Label, Randomized Study of Osimertinib versus Platinum-Based Doublet Chemotherapy for Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer whose Disease has Progressed with Previous Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy and whose Tumours harbour a T790M mutation within the Epidermal Growth Factor Receptor Gene


Options:
A: Progression Free Survival (PFS) by Investigator Assessment (RECIST tumour assessments every 6 weeks from randomisation until objective disease progression up to 19 months (at the time of the primary PFS analysis).)
B: Progression Free Survival (2-7 months)
C: Overall survival
D: Progression Free Survival (PFS) (Randomization to the first date of measured PD or death up to 37.32 months)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: A Community Paramedicine Initiative for Older Adults Living in Subsidized Housing (CHAP-EMS/Renamed to CP@Clinic)
Brief Summary: Older adults living in subsidized housing report poorer health. Their age and low income make it harder for them to use community services. Many older adults have heart disease and diabetes, which lead to frequent emergency calls and hospital admissions. To decrease the costs of treating heart disease and diabetes through emergency and hospitalization, improved screening and health education is needed. Our program will take place in communal areas within housing buildings of older adults and deliver a heart disease, diabetes, and falls risk check-up with health education. This is expected to improve the health of older adults leading to fewer emergency calls and hospital visits.


Options:
A: Change in HADS-A score from baseline to three months follow-up (Three months)
B: Depressive Symptoms (CES-D Score) (Baseline, 12 month FU)
C: Change in Canadian Diabetes Risk (CANRISK) Score (Baseline and 1 year); Change in Blood Pressure (Baseline and after each assessment (up to one year)); Change in health perceptions, behaviours, and knowledge of resources (Baseline and 1 year); Change in Health Care Utilization (Baseline and 1 year); Change in rate of EMS Calls (Baseline and 1 year)
D: Health Care Consumption (1 year); Dependence in Activities of Daily Living (1 year); Satisfaction With Health and Social Care (1 year)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: A Community Paramedicine Initiative for Older Adults Living in Subsidized Housing (CHAP-EMS/Renamed to CP@Clinic)
Brief Summary: Older adults living in subsidized housing report poorer health. Their age and low income make it harder for them to use community services. Many older adults have heart disease and diabetes, which lead to frequent emergency calls and hospital admissions. To decrease the costs of treating heart disease and diabetes through emergency and hospitalization, improved screening and health education is needed. Our program will take place in communal areas within housing buildings of older adults and deliver a heart disease, diabetes, and falls risk check-up with health education. This is expected to improve the health of older adults leading to fewer emergency calls and hospital visits.


Options:
A: Quick Inventory of Depressive Symptoms (Measured at Month 7)
B: Change in patient perception of personal self-efficacy at 6 months (6 months); Change in patient perception of self-management practice at 6 months (6 months); Change in patient perception of health behaviours at 6 months (6 months); Change in patient perception of activation at 6 month (6 months); Change in patient perception of psychological distress at 6 months (6 months)
C: Comorbidities treatment (6 months later); Auto-DAS: Patient education to calculate his Disease Activity Score (6 months after)
D: Change in Canadian Diabetes Risk (CANRISK) Score (Baseline and 1 year); Change in Blood Pressure (Baseline and after each assessment (up to one year)); Change in health perceptions, behaviours, and knowledge of resources (Baseline and 1 year); Change in Health Care Utilization (Baseline and 1 year); Change in rate of EMS Calls (Baseline and 1 year)

Answer: D