TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: STeroids to REduce Systemic Inflammation After Infant Heart Surgery (STRESS)
Brief Summary: This study's objective is to determine the pharmacokinetics (PK)/pharmacodynamics (PD), safety and efficacy of methylprednisolone in infants undergoing heart surgery with cardiopulmonary bypass. This is a prospective, double blind, multi-center, placebo-controlled safety and efficacy study. Blood samples will be collected from a subset of enrolled study participants to evaluate multiple dose methylprednisolone PK/PD. Participants will be randomized in a 1:1 fashion to intravenous methylprednisolone versus placebo. Study drug/placebo will be administered 8 to 12 hours before the anticipated start time of surgery and in the operating room at the time of initiation of cardiopulmonary bypass. Patients will be followed for primary and secondary outcomes for the duration of their hospitalization. Serious study drug-related adverse events will be collected for 7 days after the last dose of study drug.


Options:
A: Arm Label: Normal Saline; Type: PLACEBO_COMPARATOR; Interventions: Drug: Normal Saline | Arm Label: Hydrocortisone; Type: EXPERIMENTAL; Interventions: Drug: Hydrocortisone | Intervention Type: DRUG; Name: Hydrocortisone; Assigned to Arm(s): Hydrocortisone | Intervention Type: DRUG; Name: Normal Saline; Assigned to Arm(s): Normal Saline
B: Arm Label: Single dose steroid; Type: EXPERIMENTAL; Interventions: Drug: methylprednisolone (IVMP) | Arm Label: Two Dose steroid; Type: EXPERIMENTAL; Interventions: Drug: methylprednisolone (two doses IVMP) | Intervention Type: DRUG; Name: methylprednisolone (IVMP); Assigned to Arm(s): Single dose steroid | Intervention Type: DRUG; Name: methylprednisolone (two doses IVMP); Assigned to Arm(s): Two Dose steroid
C: Arm Label: Treatment; Type: EXPERIMENTAL; Interventions: Drug: Methylprednisolone | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Intervention Type: DRUG; Name: Methylprednisolone; Assigned to Arm(s): Treatment | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Placebo
D: Arm Label: Methylprednisolone Arm; Type: EXPERIMENTAL; Interventions: Drug: Methylprednisolone | Arm Label: Placebo Arm; Type: PLACEBO_COMPARATOR; Interventions: Drug: Isotonic saline | Intervention Type: DRUG; Name: Methylprednisolone; Assigned to Arm(s): Methylprednisolone Arm | Intervention Type: DRUG; Name: Isotonic saline; Assigned to Arm(s): Placebo Arm

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: CSP #599 - Transfusion Trigger After Operations in High Cardiac Risk Patients (TOP)
Brief Summary: The goal of the proposed study is to determine whether a liberal transfusion strategy (transfusion trigger at Hb \< 10 gm/dl) in Veterans at high cardiac risk who undergo major open vascular and general surgery operations is associated with decreased risk of adverse postoperative outcomes compared to a restrictive transfusion strategy (transfusion trigger at Hb \< 7 gm/dl).


Options:
A: Arm Label: Blood transfusion triggers of 24% hematocrit value; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Blood transfusion at hematocrit value less than 24% | Arm Label: Blood transfusion triggers of 28% hematocrit value; Type: ACTIVE_COMPARATOR; Interventions: Procedure: Blood transfusion at hematocrit value less than 28% | Intervention Type: PROCEDURE; Name: Blood transfusion at hematocrit value less than 24%; Assigned to Arm(s): Blood transfusion triggers of 24% hematocrit value | Intervention Type: PROCEDURE; Name: Blood transfusion at hematocrit value less than 28%; Assigned to Arm(s): Blood transfusion triggers of 28% hematocrit value
B: Arm Label: Liberal Transfusion Strategy; Type: ACTIVE_COMPARATOR; Interventions: Biological: Red blood cell transfusion | Arm Label: Restrictive Transfusion Strategy; Type: ACTIVE_COMPARATOR; Interventions: Biological: Red blood cell transfusion | Intervention Type: BIOLOGICAL; Name: Red blood cell transfusion; Assigned to Arm(s): Liberal Transfusion Strategy | Intervention Type: BIOLOGICAL; Name: Red blood cell transfusion; Assigned to Arm(s): Restrictive Transfusion Strategy
C: Arm Label: Liberal blood transfusion; Type: ACTIVE_COMPARATOR; Interventions: Biological: SAGM (Saline-Adenine-Glucose-Mannitol) blood transfusion | Arm Label: Restrictive blood transfusion; Type: ACTIVE_COMPARATOR; Interventions: Biological: SAGM (Saline-Adenine-Glucose-Mannitol) blood transfusion | Intervention Type: BIOLOGICAL; Name: SAGM (Saline-Adenine-Glucose-Mannitol) blood transfusion; Assigned to Arm(s): Liberal blood transfusion | Intervention Type: BIOLOGICAL; Name: SAGM (Saline-Adenine-Glucose-Mannitol) blood transfusion; Assigned to Arm(s): Restrictive blood transfusion
D: Arm Label: Restrictive; Type: EXPERIMENTAL; Interventions: Procedure: Blood Transfusion | Arm Label: Liberal; Type: EXPERIMENTAL; Interventions: Procedure: Blood Transfusion | Intervention Type: PROCEDURE; Name: Blood Transfusion; Assigned to Arm(s): Liberal, Restrictive

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: CSP #599 - Transfusion Trigger After Operations in High Cardiac Risk Patients (TOP)
Brief Summary: The goal of the proposed study is to determine whether a liberal transfusion strategy (transfusion trigger at Hb \< 10 gm/dl) in Veterans at high cardiac risk who undergo major open vascular and general surgery operations is associated with decreased risk of adverse postoperative outcomes compared to a restrictive transfusion strategy (transfusion trigger at Hb \< 7 gm/dl).


Options:
A: Arm Label: Restrictive RBC Transfusion Group; Type: EXPERIMENTAL; Interventions: Biological: Restrictive RBC Transfusion | Arm Label: Liberal RBC Transfusion Group; Type: EXPERIMENTAL; Interventions: Biological: Liberal RBC Transfusion | Intervention Type: BIOLOGICAL; Name: Restrictive RBC Transfusion; Assigned to Arm(s): Restrictive RBC Transfusion Group | Intervention Type: BIOLOGICAL; Name: Liberal RBC Transfusion; Assigned to Arm(s): Liberal RBC Transfusion Group
B: Arm Label: Restrictive; Type: EXPERIMENTAL; Interventions: Procedure: Blood Transfusion | Arm Label: Liberal; Type: EXPERIMENTAL; Interventions: Procedure: Blood Transfusion | Intervention Type: PROCEDURE; Name: Blood Transfusion; Assigned to Arm(s): Liberal, Restrictive
C: Intervention Type: DRUG; Name: Red blood cell transfusion; Assigned to Arm(s): N/A
D: Arm Label: Liberal; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Liberal transfusion strategy | Arm Label: Restrictive; Type: EXPERIMENTAL; Interventions: Behavioral: Restrictive transfusion strategy | Intervention Type: BEHAVIORAL; Name: Liberal transfusion strategy; Assigned to Arm(s): Liberal | Intervention Type: BEHAVIORAL; Name: Restrictive transfusion strategy; Assigned to Arm(s): Restrictive

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: CSP #599 - Transfusion Trigger After Operations in High Cardiac Risk Patients (TOP)
Brief Summary: The goal of the proposed study is to determine whether a liberal transfusion strategy (transfusion trigger at Hb \< 10 gm/dl) in Veterans at high cardiac risk who undergo major open vascular and general surgery operations is associated with decreased risk of adverse postoperative outcomes compared to a restrictive transfusion strategy (transfusion trigger at Hb \< 7 gm/dl).


Options:
A: Arm Label: Liberal Group; Type: EXPERIMENTAL; Interventions: Other: Haemoglobin 9.5 g/dL | Arm Label: Restrictive group; Type: ACTIVE_COMPARATOR; Interventions: Other: Haemoglobine 7.5g/dL | Intervention Type: OTHER; Name: Haemoglobin 9.5 g/dL; Assigned to Arm(s): Liberal Group | Intervention Type: OTHER; Name: Haemoglobine 7.5g/dL; Assigned to Arm(s): Restrictive group
B: Arm Label: Allowed drop in hemoglobin to 4.5-5.5 mmol/L; Type: ACTIVE_COMPARATOR; Interventions: Other: Allowed drop in hemoglobin to 4.5-5.5 mmol/L | Arm Label: Allowed drop in hemoglobin to 5.6-6.5 mmol/L; Type: EXPERIMENTAL; Interventions: Other: Allowed drop in hemoglobin to level between 5.6-6.5 mmol/L | Intervention Type: OTHER; Name: Allowed drop in hemoglobin to 4.5-5.5 mmol/L; Assigned to Arm(s): Allowed drop in hemoglobin to 4.5-5.5 mmol/L | Intervention Type: OTHER; Name: Allowed drop in hemoglobin to level between 5.6-6.5 mmol/L; Assigned to Arm(s): Allowed drop in hemoglobin to 5.6-6.5 mmol/L
C: Arm Label: Blood transfusion; Type: EXPERIMENTAL; Interventions: Biological: Blood transfusion | Intervention Type: BIOLOGICAL; Name: Blood transfusion; Assigned to Arm(s): Blood transfusion
D: Arm Label: Restrictive; Type: EXPERIMENTAL; Interventions: Procedure: Blood Transfusion | Arm Label: Liberal; Type: EXPERIMENTAL; Interventions: Procedure: Blood Transfusion | Intervention Type: PROCEDURE; Name: Blood Transfusion; Assigned to Arm(s): Liberal, Restrictive

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Phase II Randomised, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Orally Administered BI 409306 During a 52-week Treatment Period as an Early Intervention in Patients With Attenuated Psychosis Syndrome.
Brief Summary: This is a study in people between 16 and 30 years of age who have a specific type of mental illness called attenuated psychosis syndrome (APS). The purpose of this study is to find out whether BI 409306 helps reduce the symptoms of APS.

Participants are in the study for 1 year and 2 months. During this time, they visit the study site about 15 times and get about 10 phone calls. Participants are put into 2 groups by chance. They get either BI 409306 or placebo. Placebo tablets look like BI 409306 tablets but do not contain any medicine. Participants take a BI 409306 or placebo tablet two times a day.

During the study, participants answer questions in interviews and complete questionnaires so the doctors can check whether the APS symptoms change. The doctors also check the general health of the participants.


Options:
A: Arm Label: Standard treatment + cognitive remediation; Type: EXPERIMENTAL; Interventions: Behavioral: Cognitive remediation, Behavioral: Standard treatment | Arm Label: Standard treatment; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Standard treatment | Intervention Type: BEHAVIORAL; Name: Cognitive remediation; Assigned to Arm(s): Standard treatment + cognitive remediation | Intervention Type: BEHAVIORAL; Name: Standard treatment; Assigned to Arm(s): Standard treatment, Standard treatment + cognitive remediation
B: Arm Label: A; Type: EXPERIMENTAL; Interventions: Drug: Omega 3 fatty acids | Arm Label: B; Type: PLACEBO_COMPARATOR; Interventions: Drug: Omega 3 fatty acids | Intervention Type: DRUG; Name: Omega 3 fatty acids; Assigned to Arm(s): A, B
C: Intervention Type: BEHAVIORAL; Name: Integrated treatment, family involvement; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: Social skills training; Assigned to Arm(s): N/A
D: Arm Label: BI 409306; Type: EXPERIMENTAL; Interventions: Drug: BI 409306 | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: BI 409306; Assigned to Arm(s): BI 409306 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Does the Enhanced Rehabilitation Programs Facilitate the Motor Recovery After Stroke? A Multicenter Randomized Controlled Study (TIARAS Trial)
Brief Summary: Study purpose This study will explore whether an additional rehabilitation program that focus on either upper or lower extremity training facilitate the recovery in upper or lower extremity.

The recovery in both neurological status and motor functions will be explored.


Options:
A: Arm Label: Robot-Low; Type: EXPERIMENTAL; Interventions: Other: Robot-Low | Arm Label: Robot-High; Type: EXPERIMENTAL; Interventions: Other: Robot-High | Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Other: Control | Intervention Type: OTHER; Name: Robot-Low; Assigned to Arm(s): Robot-Low | Intervention Type: OTHER; Name: Robot-High; Assigned to Arm(s): Robot-High | Intervention Type: OTHER; Name: Control; Assigned to Arm(s): Control
B: Arm Label: group 1: standard physiotherapy; Type: PLACEBO_COMPARATOR; Interventions: Procedure: standard physiotherapy | Arm Label: group 2: experimental physiotherapy; Type: EXPERIMENTAL; Interventions: Procedure: experimental physiotherapy | Intervention Type: PROCEDURE; Name: standard physiotherapy; Assigned to Arm(s): group 1: standard physiotherapy | Intervention Type: PROCEDURE; Name: experimental physiotherapy; Assigned to Arm(s): group 2: experimental physiotherapy
C: Arm Label: enhanced upper-extremity program, EUEP; Type: EXPERIMENTAL; Interventions: Other: UFT | Arm Label: enhanced lower-extremity program,ELLP); Type: EXPERIMENTAL; Interventions: Other: LFT | Intervention Type: OTHER; Name: UFT; Assigned to Arm(s): enhanced upper-extremity program, EUEP | Intervention Type: OTHER; Name: LFT; Assigned to Arm(s): enhanced lower-extremity program,ELLP)
D: Arm Label: usual management; Type: OTHER; Interventions: Other: no physical activity | Arm Label: physical training; Type: EXPERIMENTAL; Interventions: Other: physical activity | Intervention Type: OTHER; Name: no physical activity; Assigned to Arm(s): usual management | Intervention Type: OTHER; Name: physical activity; Assigned to Arm(s): physical training

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Randomized Controlled Trial to Improve Multisensory Neural Processing, Language & Motor Outcomes in Preterm Infants
Brief Summary: Every year, almost all of ½ million infants born prematurely in the US and 15 million worldwide suffer from abnormal brain maturation resulting from interactions between immaturity and atypical sensory experiences after birth. This study uses rigorous scientific methods to measure the effects and determine the mechanisms of action of a parent-supported multisensory neurorehabilitative intervention for preterm infants, adaptable to a wide variety of neonatal environments, even when parents cannot be at their child's bedside. The intervention aims to improve brain multisensory processing, reactions to sensory stimulation in the home and long term language and motor development.


Options:
A: Arm Label: MT during and after NICU; Type: EXPERIMENTAL; Interventions: Behavioral: MT during NICU, Behavioral: MT after NICU, Other: Standard care | Arm Label: MT during NICU; Type: EXPERIMENTAL; Interventions: Behavioral: MT during NICU, Other: Standard care | Arm Label: MT after NICU; Type: EXPERIMENTAL; Interventions: Behavioral: MT after NICU, Other: Standard care | Arm Label: No MT; Type: EXPERIMENTAL; Interventions: Other: Standard care | Intervention Type: BEHAVIORAL; Name: MT during NICU; Assigned to Arm(s): MT during NICU, MT during and after NICU | Intervention Type: BEHAVIORAL; Name: MT after NICU; Assigned to Arm(s): MT after NICU, MT during and after NICU | Intervention Type: OTHER; Name: Standard care; Assigned to Arm(s): MT after NICU, MT during NICU, MT during and after NICU, No MT
B: Arm Label: Multisensory Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Therapist skin-to-skin Care, Device: Contingent parent's voice exposure, Behavioral: Parental skin-to-skin care, Device: Recorded parent's voice | Arm Label: Standard of Care; Type: OTHER; Interventions: Behavioral: Parental skin-to-skin care, Device: Recorded parent's voice | Intervention Type: BEHAVIORAL; Name: Therapist skin-to-skin Care; Assigned to Arm(s): Multisensory Intervention | Intervention Type: DEVICE; Name: Contingent parent's voice exposure; Assigned to Arm(s): Multisensory Intervention | Intervention Type: BEHAVIORAL; Name: Parental skin-to-skin care; Assigned to Arm(s): Multisensory Intervention, Standard of Care | Intervention Type: DEVICE; Name: Recorded parent's voice; Assigned to Arm(s): Multisensory Intervention, Standard of Care
C: Arm Label: music therapy; Type: EXPERIMENTAL; Interventions: Procedure: Music Therapy | Arm Label: control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: PROCEDURE; Name: Music Therapy; Assigned to Arm(s): music therapy
D: Arm Label: Maternal voice; Type: EXPERIMENTAL; Interventions: Other: Maternal voice | Arm Label: control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Maternal voice; Assigned to Arm(s): Maternal voice

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Randomized Controlled Trial to Improve Multisensory Neural Processing, Language & Motor Outcomes in Preterm Infants
Brief Summary: Every year, almost all of ½ million infants born prematurely in the US and 15 million worldwide suffer from abnormal brain maturation resulting from interactions between immaturity and atypical sensory experiences after birth. This study uses rigorous scientific methods to measure the effects and determine the mechanisms of action of a parent-supported multisensory neurorehabilitative intervention for preterm infants, adaptable to a wide variety of neonatal environments, even when parents cannot be at their child's bedside. The intervention aims to improve brain multisensory processing, reactions to sensory stimulation in the home and long term language and motor development.


Options:
A: Intervention Type: BEHAVIORAL; Name: Sensitizing parents; Assigned to Arm(s): N/A
B: Arm Label: Multisensory Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Therapist skin-to-skin Care, Device: Contingent parent's voice exposure, Behavioral: Parental skin-to-skin care, Device: Recorded parent's voice | Arm Label: Standard of Care; Type: OTHER; Interventions: Behavioral: Parental skin-to-skin care, Device: Recorded parent's voice | Intervention Type: BEHAVIORAL; Name: Therapist skin-to-skin Care; Assigned to Arm(s): Multisensory Intervention | Intervention Type: DEVICE; Name: Contingent parent's voice exposure; Assigned to Arm(s): Multisensory Intervention | Intervention Type: BEHAVIORAL; Name: Parental skin-to-skin care; Assigned to Arm(s): Multisensory Intervention, Standard of Care | Intervention Type: DEVICE; Name: Recorded parent's voice; Assigned to Arm(s): Multisensory Intervention, Standard of Care
C: Arm Label: Implement Family Integrated Care; Type: EXPERIMENTAL; Interventions: Other: Implement Family Integrated Care | Arm Label: Monitor Standard Practices; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Implement Family Integrated Care; Assigned to Arm(s): Implement Family Integrated Care
D: Arm Label: Term group; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Usual care program group; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Clinic-based interveniton program group; Type: EXPERIMENTAL; Interventions: Behavioral: clinic-based intervention program and home-based intervention program | Arm Label: Home-based interveniton program group; Type: EXPERIMENTAL; Interventions: Behavioral: clinic-based intervention program and home-based intervention program | Intervention Type: BEHAVIORAL; Name: clinic-based intervention program and home-based intervention program; Assigned to Arm(s): Clinic-based interveniton program group, Home-based interveniton program group

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effectiveness of MOVI Interventions on Improving Adiposity, Cognition and Motor Competence by Increasing Aerobic Cardiorespiratory Fitness: MOVI-da10!
Brief Summary: Project which objective is to test the effectiveness of a classroom-based physical activity intervention (MOVI-da10!) on improving, body composition, cardio-respiratory fitness and executive function.


Options:
A: Arm Label: Internet-supported FeetEnergy approach; Type: EXPERIMENTAL; Interventions: Behavioral: Internet-supported FeetEnergy approach | Arm Label: Usual health education; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Usual health education | Intervention Type: BEHAVIORAL; Name: Internet-supported FeetEnergy approach; Assigned to Arm(s): Internet-supported FeetEnergy approach | Intervention Type: BEHAVIORAL; Name: Usual health education; Assigned to Arm(s): Usual health education
B: Arm Label: MOVI-KIDS Program; Type: EXPERIMENTAL; Interventions: Behavioral: MOVI-KIDS | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: MOVI-KIDS; Assigned to Arm(s): MOVI-KIDS Program
C: Arm Label: Physical activity intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Physical activity intervention | Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Usual practice | Intervention Type: BEHAVIORAL; Name: Physical activity intervention; Assigned to Arm(s): Physical activity intervention | Intervention Type: BEHAVIORAL; Name: Usual practice; Assigned to Arm(s): Control
D: Arm Label: MOVI-da 10! active breaks; Type: EXPERIMENTAL; Interventions: Behavioral: MOVI-da10! active breaks | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: MOVI-da10! integrated physical activity; Type: EXPERIMENTAL; Interventions: Behavioral: MOVI-da10! integrated physical activity | Intervention Type: BEHAVIORAL; Name: MOVI-da10! active breaks; Assigned to Arm(s): MOVI-da 10! active breaks | Intervention Type: BEHAVIORAL; Name: MOVI-da10! integrated physical activity; Assigned to Arm(s): MOVI-da10! integrated physical activity

Answer: D