Please select the eligibility criteria that correspond to the clinical trial below.
Title: Evaluation of the Effects of Ketamine in the Acute Phase of Suicidal Ideation: a Multicenter Randomized Double-blind Trial
Brief Summary: The primary objective of this study is to assess the efficacy of ketamine versus a placebo for the short-term (at 72h, i.e. 24h after the last perfusion) relief of suicidal ideation, measured using the BSS hetero questionnaire, in patients hospitalized for suicide risk.


Options:
A: Inclusion Criteria:

* French speaking patients freely hospitalized for prevention of suicide and who have a medium or high suicide risk score according to a MINI structured interview
* The patient is able to understand how the study is carried out and the tests performed
* The patient is deemed capable of giving his/her informed consent
* The patient has been correctly informed
* The patient must have given his/her informed and signed consent.
* The patient must be insured or beneficiary of a health insurance plan.
* Presence of suicidal ideation according to the SSI score (score \> 3)
* Negative pregnancy test for women of childbearing age

Exclusion Criteria:

* The patient is participating in another interventional study
* Within the past three months, the patient has participated in another interventional study
* The patient is in an exclusion period determined by a previous study
* The patient is under judicial protection
* The patient is an adult under guardianship
* The patient refuses to sign the consent
* The patient is not able to understand the informed consent
* Pregnancy or breastfeeding
* History of schizophrenia or other psychotic disorders
* Presence of psychotic symptoms at initial interview
* Schizoid or schizotypic personality disorder
* Positive urine screening for illicit substances, excluding cannabis
* Substance dependence in the preceding month (excluding nicotine or caffeine)
* Concomitant treatment with electroconvulsive therapy
* Unstable somatic pathology
* Clinically significant anomalies found during clinical examination, biological test or ECG
* Non-stabilized hypertension or hypertension \> 180/100
* Known or suspected contra-indication for ketamine (includes interactions): hypersensitivity to ketamine, hypertension, class IV cardiac insufficiency, history of stroke, hepatic or cutaneous porphyria, history of intracranial hypertension
B: Inclusion Criteria:

* Identifies as an African-American female
* Abusive relationship within the 12 months prior to study entry
* Suicide attempt within the 12 months prior to study entry
* Seeks services at Grady Health System

Exclusion Criteria:

* Score of less than 22 on Mini Mental Status Exam (MMSE)
* Score of less than 18 on Rapid Estimate of Adult Literacy in Medicine (REALM)
* Acutely psychotic
C: Inclusion criteria:

* Between 18 and 65 years
* Having signed informed consent
* Main diagnosis of major depressive episode (DSM-5 criteria)
* History of suicide attempt within the year
* Able to understand nature, aims, methodology of the study and agree to cooperate in clinical, radiological assessments.

Exclusion criteria:

* Current diagnosis of substance abuse or dependence in the last 6 months (including tobacco and alcohol)
* Current lifetime diagnosis of schizophrenia, or schizoaffective disorder
* Current diagnosis of manic, hypomanic according to DSM-5 criteria
* Contraindications for the use of MRI, : metallic artificial heart valve, pacemaker, ferromagnetic cerebrovascular clips, metallic foreign body including brain mobilized or intraocular ferromagnetic prosthesis impossibility of absolute immobility, claustrophobia.
* Lifetime history of traumatic brain injury with loss of consciousness
* Pregnancy
* Patient on protective measures (guardianship or trusteeship)
* Patient for which the maximum annual amount of allowances 4 500 euros has been reached
D: Inclusion Criteria:

* self-identify as African American or Black
* speak English
* present to medical and psychiatric emergency rooms at Grady Health System following a suicide attempt
* moderate level of intent associated with the attempt (SSI \>= 8 required)
* Mini Mental State Exam (MMSE) score \> 22

Exclusion Criteria:

* significant cognitive impairments (MMSE \< 22)
* active psychosis (diagnosed based on Psychotic Screen (PS))
* imminently life-threatening medical condition

Answer: A