Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A PHASE 4, MULTICENTER, OPEN-LABEL SAFETY STUDY OF CRISABOROLE OINTMENT 2% IN CHILDREN AGED 3 MONTHS TO LESS THAN 24 MONTHS WITH MILD TO MODERATE ATOPIC DERMATITIS
Brief Summary: This 4-week study will evaluate the safety, pharmacokinetics (PK), and efficacy of crisaborole ointment 2%, applied twice daily (BID) in subjects who are 3 months to less than 24 months of age with mild-to-moderate AD.


Options:
A: Arm Label: 1. Protopic Exposure; Type: N/A; Interventions: N/A
B: Arm Label: Crisaborole ointment 2%; Type: EXPERIMENTAL; Interventions: Drug: Crisaborole ointment 2% | Intervention Type: DRUG; Name: Crisaborole ointment 2%; Assigned to Arm(s): Crisaborole ointment 2%
C: Arm Label: Double Blind (DB): Vehicle BID; Type: PLACEBO_COMPARATOR; Interventions: Drug: Vehicle Cream BID | Arm Label: DB: Triamcinolone (TAC) 0.1% BID/Vehicle Cream BID; Type: ACTIVE_COMPARATOR; Interventions: Drug: Triamcinolone 0.1% Cream BID, Drug: Vehicle Cream BID | Arm Label: DB: Ruxolitinib 0.15% Once Daily (QD); Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 0.15% Cream QD | Arm Label: DB: Ruxolitinib 0.5% QD; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 0.5% Cream QD | Arm Label: DB: Ruxolitinib 1.5% QD; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 1.5% Cream QD | Arm Label: DB: Ruxolitinib 1.5% BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 1.5% Cream BID | Arm Label: Open-Label (OL): Vehicle BID to Ruxolitinib 1.5% BID; Type: PLACEBO_COMPARATOR; Interventions: Drug: Ruxolitinib 1.5% Cream BID | Arm Label: OL: TAC BID/Vehicle BID to Ruxolitinib 1.5% BID; Type: ACTIVE_COMPARATOR; Interventions: Drug: Ruxolitinib 1.5% Cream BID | Arm Label: OL: Ruxolitinib 0.15% QD to Ruxolitinib 1.5% BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 1.5% Cream BID | Arm Label: OL: Ruxolitinib 0.5% QD to Ruxolitinib 1.5% BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 1.5% Cream BID | Arm Label: OL: Ruxolitinib 1.5% QD to Ruxolitinib 1.5% BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 1.5% Cream BID | Arm Label: OL: Ruxolitinib 1.5% BID to Ruxolitinib 1.5% BID; Type: EXPERIMENTAL; Interventions: Drug: Ruxolitinib 1.5% Cream BID | Intervention Type: DRUG; Name: Ruxolitinib 0.15% Cream QD; Assigned to Arm(s): DB: Ruxolitinib 0.15% Once Daily (QD) | Intervention Type: DRUG; Name: Ruxolitinib 0.5% Cream QD; Assigned to Arm(s): DB: Ruxolitinib 0.5% QD | Intervention Type: DRUG; Name: Ruxolitinib 1.5% Cream QD; Assigned to Arm(s): DB: Ruxolitinib 1.5% QD | Intervention Type: DRUG; Name: Ruxolitinib 1.5% Cream BID; Assigned to Arm(s): DB: Ruxolitinib 1.5% BID, OL: Ruxolitinib 0.15% QD to Ruxolitinib 1.5% BID, OL: Ruxolitinib 0.5% QD to Ruxolitinib 1.5% BID, OL: Ruxolitinib 1.5% BID to Ruxolitinib 1.5% BID, OL: Ruxolitinib 1.5% QD to Ruxolitinib 1.5% BID, OL: TAC BID/Vehicle BID to Ruxolitinib 1.5% BID, Open-Label (OL): Vehicle BID to Ruxolitinib 1.5% BID | Intervention Type: DRUG; Name: Triamcinolone 0.1% Cream BID; Assigned to Arm(s): DB: Triamcinolone (TAC) 0.1% BID/Vehicle Cream BID | Intervention Type: DRUG; Name: Vehicle Cream BID; Assigned to Arm(s): DB: Triamcinolone (TAC) 0.1% BID/Vehicle Cream BID, Double Blind (DB): Vehicle BID
D: Arm Label: Treatment group A; Type: EXPERIMENTAL; Interventions: Drug: Tofacitinib ointment 20mg/g | Arm Label: Treatment B; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo ointment (Vehicle) | Intervention Type: DRUG; Name: Tofacitinib ointment 20mg/g; Assigned to Arm(s): Treatment group A | Intervention Type: DRUG; Name: Placebo ointment (Vehicle); Assigned to Arm(s): Treatment B

Answer: B