Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Effects of a Rhythm and Music-based Therapy Program and Therapeutic Riding in Late Recovery Phase Following Stroke
Brief Summary: The initiative to the study is based on the fact that various forms of enriched environments and multimodal stimulation are found to have positive influences on motivation and psychosocial well-being and have been shown to facilitate multiple processes in the brain leading to structural regeneration and functional recovery. Since there is a lack of rehabilitation programs that encompass all dimensions of a stroke survivor's life researchers agree upon the need for a rehabilitation program that addresses both the social and physical needs of the patients. The aim with the project is to investigate whether it is possible to improve the life situation among patients with a history of stroke through a rhythm and music method and therapeutic riding. To get insights in the underlying mechanisms our research also focuses on relevant physiological, neurobiological and psychosocial mechanisms induced by the interventions. The hypothesis is that both treatment methods will mainly enhance participants' degree of participation.

The study is a randomized controlled trial where about 123 participants (50-75 years old) who had their stroke incident 1 - 5 years ago will be consecutively included and randomly allocated to the following three groups: a) Ronnie Gardiner Rhythm Music Method (RGRM) b) therapeutic riding c) a control group receiving RGRM after 9 months. Treatment proceeds during 12 weeks and evaluation takes place pre- and post intervention, and 12 and 24 weeks after the treatment is finalized. The evaluation consists of a thorough neuropsychological assessment, a physiotherapeutic assessment, sampling of blood and questionnaires covering mental, psychosocial, physical and psychological well-being. Interviews are also conducted in order to map the participants' experiences from the two treatment programs. Specially designed interviews are also planned to be carried through with participants having aphasia.

So far, there is only empirical support suggesting that RGRM has positive effects for individuals with a history of stroke making it significant to carry out research with the aim to contribute to strengthening the evidence of the method. A positive outcome would increase the scientific basis for this alternative treatment thus facilitating further research and implementation in everyday clinical practice.


Options:
A: Inclusion Criteria:

* Aged 50 - 75 years
* Disability grade 2 or 3 on MRS\*)
* Being in the late-phase of stroke (1 - 5 years after an ischemic or hemorrhagic stroke)
* Ability to understand written and oral information and instructions in Swedish
* Having an own housing
* Ability to travel to the place of intervention and evaluation
* No need for personal assistance in activities of daily living while participating in the treatment (going to the toilet, transport/transportation services for disabled, walking)

Exclusion Criteria:

* Disability rated ˂ 2 or ˃ 3 on MRS\*)
* Pronounced fear of horses or allergy constituting a risk for the patients to participate in the therapeutic riding
* Heart conditions that constitutes a risk for the individual to participate in the interventions
* Non-controlled epileptic seizures constituting a risk for the patients to participate in the intervention
* Lack of cognitive and/or verbal ability that makes it difficult for the individual to understand instructions and/or evaluation
* Total paralysis of the affected arm
* Injury or disease that makes the individual not suitable for the trial
* Weight ˃ 95 kg (in order to spare the horses)
* Having more than a half-time employment
* Injury, disease or addiction that make the individual not suitable for the trial
* Participation in RGRM or therapeutic riding during the year prior to inclusion
* Having an additional stroke within the past year (TIA is however accepted)
* Lack of willingness to participate in both treatment methods
* Living ˃ 80 km from Gothenburg
* Dependent on transportation services for disabled across the community border which is not allowed according to the regulation
B: Inclusion Criteria:

* Symptomatic ischemic stroke with clinical syndrome of stroke and a corresponding ischemic lesion.
* MRI or CT results compatible with clinical diagnosis of acute ischemic stroke
* NIH Stroke Scale Score on admission 1 to 14, both inclusive
* Modified Rankin Scale before stroke 0 to 2, inclusive
* Randomization within 3 months after stroke onset (goal: 80% within 3 weeks)
* Sufficient communication possible
* Informed consent given by the patient and/or the patient's legally acceptable representative

Exclusion Criteria:

* Substantial cognitive decline (Mini Mental State Examination (MMSE) score \> 24) or pre-existing dementia or Parkinson disease
* Persistent disturbed level of consciousness
* Persistent aphasia
* Pre-existing significant psychiatric diseases (i.e. Schizophrenia, Major Depression, Bipolar Disorders, all according to DSMIV); Patients with minor Depression (DSM IV) can be included
* Severe sensory impairment making neuropsychological testing impossible
* Severe comorbidity (e.g. unstable or severe cardiovascular or pulmonal disease, neoplasm, severe liver or renal insufficiency and symptomatic stenosis of the ipsilateral carotid artery, cancer...)
* Unreliability for follow up
* Unwillingness or inability to participate or to sign the informed consent
C: Inclusion

* mild to moderate stroke
* traumatic brain-injury
* deficits in attention defined by the APT test
* lower average and above for reasoning skills
* lower average and above for abstract thinking
* good understanding of the Swedish language

Exclusion

* moderate to severe aphasia
* ongoing psychiatric illness
* history of severe somatic disorder causing anoxic periods
* ongoing substance abuse
* severe pain severe memory disorders,
* neglect
* visual field defects
* motor disability interfering with participation
D: Inclusion Criteria:

* Aged 18 years of age or greater
* Admitted to out-patient rehabilitation post ischemic stroke

Exclusion Criteria:

* more than 6 months post stroke onset
* those not requiring occupational therapy
* hemorrhagic stroke
* neurological diagnoses other than stroke
* major psychiatric illness
* moderate or severe aphasia (NIH Stroke Scale aphasia rating of 2 or more)
* dementia (Mini Mental State Exam scores of 24 or less)

Answer: A