Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized, Double-blind, Placebo-controlled, Parallel Group, Stratified, Multi-center, 12-Week Study Comparing the Safety and Efficacy of Fluticasone and Formoterol Combination (FlutiForm(tm) 100/10 µg or 250/10 µg Twice Daily) in a Single Inhaler (SkyePharma HFA pMDI) With the Administration of Placebo or Fluticasone (250 µg Twice Daily) and Formoterol (10 µg Twice Daily) Alone in Adolescent and Adult Patients With Moderate to Severe Asthma
Brief Summary: The purpose of this study is to compare the efficacy and safety of the fixed combination asthma drug FlutiForm with its two components administered alone, fluticasone propionate and formoterol fumarate, and with placebo in adult and adolescent patients with moderate to severe asthma.


Options:
A: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: Fluticasone propionate/Formoterol fumarate 250/10 | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Drug: Fluticasone propionate/Formoterol fumarate 100/10 | Arm Label: 3; Type: ACTIVE_COMPARATOR; Interventions: Drug: Fluticasone propionate 250 | Arm Label: 4; Type: ACTIVE_COMPARATOR; Interventions: Drug: Formoterol fumarate 10 | Arm Label: 5; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Fluticasone propionate/Formoterol fumarate 250/10; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): 5 | Intervention Type: DRUG; Name: Fluticasone propionate/Formoterol fumarate 100/10; Assigned to Arm(s): 2 | Intervention Type: DRUG; Name: Fluticasone propionate 250; Assigned to Arm(s): 3 | Intervention Type: DRUG; Name: Formoterol fumarate 10; Assigned to Arm(s): 4
B: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Drug: budesonide/formoterol (Symbicort) | Intervention Type: DRUG; Name: budesonide/formoterol (Symbicort); Assigned to Arm(s): 1
C: Arm Label: FF/VI 200/25mcg once daily; Type: EXPERIMENTAL; Interventions: Drug: GW685698/GW642444 | Arm Label: Fluticasone propionate 500mcg twice daily; Type: ACTIVE_COMPARATOR; Interventions: Drug: CCI18781 | Intervention Type: DRUG; Name: GW685698/GW642444; Assigned to Arm(s): FF/VI 200/25mcg once daily | Intervention Type: DRUG; Name: CCI18781; Assigned to Arm(s): Fluticasone propionate 500mcg twice daily
D: Arm Label: FF/UMEC/VI (100/31.25/25) mcg closed triple therapy; Type: EXPERIMENTAL; Interventions: Drug: FF/UMEC/VI (100/31.25/25) mcg, Drug: FF/VI (100/25) mcg, Drug: Fluticasone/salmeterol (FSC), Drug: Albuterol/salbutamol, Device: ELLIPTA DPI, Device: DISKUS DPI, Device: METERED-DOSE INHALER (MDI) | Arm Label: FF/UMEC/VI (100/62.5/25) mcg closed triple therapy; Type: EXPERIMENTAL; Interventions: Drug: FF/UMEC/VI (100/62.5/25) mcg, Drug: FF/VI (100/25) mcg, Drug: Fluticasone/salmeterol (FSC), Drug: Albuterol/salbutamol, Device: ELLIPTA DPI, Device: DISKUS DPI, Device: METERED-DOSE INHALER (MDI) | Arm Label: FF/UMEC/VI (200/31.25/25) mcg closed triple therapy; Type: EXPERIMENTAL; Interventions: Drug: FF/UMEC/VI (200/31.25/25) mcg, Drug: FF/VI (100/25) mcg, Drug: Fluticasone/salmeterol (FSC), Drug: Albuterol/salbutamol, Device: ELLIPTA DPI, Device: DISKUS DPI, Device: METERED-DOSE INHALER (MDI) | Arm Label: FF/UMEC/VI (200/62.5/25) mcg closed triple therapy; Type: EXPERIMENTAL; Interventions: Drug: FF/UMEC/VI (200/62.5/25) mcg, Drug: FF/VI (100/25) mcg, Drug: Fluticasone/salmeterol (FSC), Drug: Albuterol/salbutamol, Device: ELLIPTA DPI, Device: DISKUS DPI, Device: METERED-DOSE INHALER (MDI) | Arm Label: FF/VI (100/25) mcg dual combination therapy; Type: ACTIVE_COMPARATOR; Interventions: Drug: FF/VI (100/25) mcg, Drug: Fluticasone/salmeterol (FSC), Drug: Albuterol/salbutamol, Device: ELLIPTA DPI, Device: DISKUS DPI, Device: METERED-DOSE INHALER (MDI) | Arm Label: FF/VI (200/25) mcg dual combination therapy; Type: ACTIVE_COMPARATOR; Interventions: Drug: FF/VI (100/25) mcg, Drug: FF/VI (200/25) mcg, Drug: Fluticasone/salmeterol (FSC), Drug: Albuterol/salbutamol, Device: ELLIPTA DPI, Device: DISKUS DPI, Device: METERED-DOSE INHALER (MDI) | Intervention Type: DRUG; Name: FF/UMEC/VI (100/31.25/25) mcg; Assigned to Arm(s): FF/UMEC/VI (100/31.25/25) mcg closed triple therapy | Intervention Type: DRUG; Name: FF/UMEC/VI (100/62.5/25) mcg; Assigned to Arm(s): FF/UMEC/VI (100/62.5/25) mcg closed triple therapy | Intervention Type: DRUG; Name: FF/UMEC/VI (200/31.25/25) mcg; Assigned to Arm(s): FF/UMEC/VI (200/31.25/25) mcg closed triple therapy | Intervention Type: DRUG; Name: FF/UMEC/VI (200/62.5/25) mcg; Assigned to Arm(s): FF/UMEC/VI (200/62.5/25) mcg closed triple therapy | Intervention Type: DRUG; Name: FF/VI (100/25) mcg; Assigned to Arm(s): FF/UMEC/VI (100/31.25/25) mcg closed triple therapy, FF/UMEC/VI (100/62.5/25) mcg closed triple therapy, FF/UMEC/VI (200/31.25/25) mcg closed triple therapy, FF/UMEC/VI (200/62.5/25) mcg closed triple therapy, FF/VI (100/25) mcg dual combination therapy, FF/VI (200/25) mcg dual combination therapy | Intervention Type: DRUG; Name: FF/VI (200/25) mcg; Assigned to Arm(s): FF/VI (200/25) mcg dual combination therapy | Intervention Type: DRUG; Name: Fluticasone/salmeterol (FSC); Assigned to Arm(s): FF/UMEC/VI (100/31.25/25) mcg closed triple therapy, FF/UMEC/VI (100/62.5/25) mcg closed triple therapy, FF/UMEC/VI (200/31.25/25) mcg closed triple therapy, FF/UMEC/VI (200/62.5/25) mcg closed triple therapy, FF/VI (100/25) mcg dual combination therapy, FF/VI (200/25) mcg dual combination therapy | Intervention Type: DRUG; Name: Albuterol/salbutamol; Assigned to Arm(s): FF/UMEC/VI (100/31.25/25) mcg closed triple therapy, FF/UMEC/VI (100/62.5/25) mcg closed triple therapy, FF/UMEC/VI (200/31.25/25) mcg closed triple therapy, FF/UMEC/VI (200/62.5/25) mcg closed triple therapy, FF/VI (100/25) mcg dual combination therapy, FF/VI (200/25) mcg dual combination therapy | Intervention Type: DEVICE; Name: ELLIPTA DPI; Assigned to Arm(s): FF/UMEC/VI (100/31.25/25) mcg closed triple therapy, FF/UMEC/VI (100/62.5/25) mcg closed triple therapy, FF/UMEC/VI (200/31.25/25) mcg closed triple therapy, FF/UMEC/VI (200/62.5/25) mcg closed triple therapy, FF/VI (100/25) mcg dual combination therapy, FF/VI (200/25) mcg dual combination therapy | Intervention Type: DEVICE; Name: DISKUS DPI; Assigned to Arm(s): FF/UMEC/VI (100/31.25/25) mcg closed triple therapy, FF/UMEC/VI (100/62.5/25) mcg closed triple therapy, FF/UMEC/VI (200/31.25/25) mcg closed triple therapy, FF/UMEC/VI (200/62.5/25) mcg closed triple therapy, FF/VI (100/25) mcg dual combination therapy, FF/VI (200/25) mcg dual combination therapy | Intervention Type: DEVICE; Name: METERED-DOSE INHALER (MDI); Assigned to Arm(s): FF/UMEC/VI (100/31.25/25) mcg closed triple therapy, FF/UMEC/VI (100/62.5/25) mcg closed triple therapy, FF/UMEC/VI (200/31.25/25) mcg closed triple therapy, FF/UMEC/VI (200/62.5/25) mcg closed triple therapy, FF/VI (100/25) mcg dual combination therapy, FF/VI (200/25) mcg dual combination therapy

Answer: A