TrialPanorama/Dataset huggingface dataset:
Please select the outcome measures that correspond to the clinical trial below.
Title: Effectiveness of a Resistance Training Program in the Workplace to Muscle Fatigue Control in Industrial Workers: Cluster Randomized Controlled Trial.
Brief Summary: Studies show that exercise resistance in workplace can reduce the symptoms of induced labor, however, the effectiveness of such programs depends on the characteristics of the training fatigue. Thus, it is expected that this study the intervention group with training heavy using progressive resistance exercise protocol will be better in reducing fatigue when compare with light training group.


Options:
A: Need for Recovery (up to 4 months); Fatigue (up to 4 months)
B: Physical Activity (Measured 5 times over 13 months, for seven days each time. Time points = baseline, 1-2weeks, 3 months, 6 months and 12 months)
C: muscle strength (3 months); Aerobic capacity (3 months)
D: Change in Body Weight (Baseline, 6 months, 12 months); Change in Waist Circumference (Baseline, 6 months,12 months)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Group Therapy for Adolescents With Attention-Deficit/Hyperactivity Disorder: a Randomized Multicenter Controlled Trial
Brief Summary: This is the first randomized controlled study that tests the efficacy of a cognitive-behavioral group therapy (CBT) on adolescents with ADHD who were in pharmacological treatment but still presented persistent symptoms.


Options:
A: Rule Violations During Direct Classroom Observation at Endpoint (Week 8) (Endpoint (Week 8))
B: Symptoms of Attention Deficit Hyperactivity Disorder as defined by DSMIV/V. (change from baseline on ADHD symptoms at 12 weeks)
C: change in ADHD-rating scale (baseline,after the training (12week))
D: Post-treatment ADHD symptoms (Post-treatment (after receiving 3 month treatment)); Post-treatment functional impairment (Post-treatment (after receiving 3 month treatment))

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: The Influence of Sit-stand Workstations Upon Total Physical Activity: a 12 Month Randomised Controlled Trial
Brief Summary: The purpose of this study is to examine the contribution of sit-stand workstations to total daily physical activity in a multi-component office-based 12 month intervention.


Options:
A: Physical Activity (Measured 5 times over 13 months, for seven days each time. Time points = baseline, 1-2weeks, 3 months, 6 months and 12 months)
B: Change from control week and intervention week in total energy expenditure (TEE) (week 1 and week 2); Resting energy expenditure (REE) (Baseline (day 0)); Change from control week and intervention week in physical activity energy expenditure (PAEE) (week 1 and week 2); Change from control week and intervention week in daily time spent in sedentary (SB) (week 1 and week 2); Change from control week and intervention week in light (LIPA), moderate and vigorous (MVPA) intensity activities (week 1 and week 2); Change from control week and intervention week in number of breaks in sedentary time (BST) (week 1 and week 2); Change from control week and intervention week in time spent sitting (TSS) (week 1 and week 2); Change from control week and intervention week in time spent standing (TSst) (week 1 and week 2); Change from control week and intervention week in time spent walking (TSW) (week 1 and week 2); Change from control week and intervention week in number of steps (week 1 and week 2)
C: Daily sitting time (baseline and 23 weeks)
D: sitting time (one week); self-reported context-specific sitting time (one week); standing time (one week); breaks from sitting (one week)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: The Influence of Sit-stand Workstations Upon Total Physical Activity: a 12 Month Randomised Controlled Trial
Brief Summary: The purpose of this study is to examine the contribution of sit-stand workstations to total daily physical activity in a multi-component office-based 12 month intervention.


Options:
A: Physical Activity (Measured 5 times over 13 months, for seven days each time. Time points = baseline, 1-2weeks, 3 months, 6 months and 12 months)
B: To assess the effectiveness of a 6-month primary care intervention to reduce diary hours of Sitting time in overweight and obese patients, as well as to increase their weekly caloric spend (Baseline-6-9-12 and 18 month)
C: Change in Occupational Physical Activity From Baseline to 16 Weeks (Baseline and 16 weeks)
D: Change from control week and intervention week in total energy expenditure (TEE) (week 1 and week 2); Resting energy expenditure (REE) (Baseline (day 0)); Change from control week and intervention week in physical activity energy expenditure (PAEE) (week 1 and week 2); Change from control week and intervention week in daily time spent in sedentary (SB) (week 1 and week 2); Change from control week and intervention week in light (LIPA), moderate and vigorous (MVPA) intensity activities (week 1 and week 2); Change from control week and intervention week in number of breaks in sedentary time (BST) (week 1 and week 2); Change from control week and intervention week in time spent sitting (TSS) (week 1 and week 2); Change from control week and intervention week in time spent standing (TSst) (week 1 and week 2); Change from control week and intervention week in time spent walking (TSW) (week 1 and week 2); Change from control week and intervention week in number of steps (week 1 and week 2)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: The Influence of Sit-stand Workstations Upon Total Physical Activity: a 12 Month Randomised Controlled Trial
Brief Summary: The purpose of this study is to examine the contribution of sit-stand workstations to total daily physical activity in a multi-component office-based 12 month intervention.


Options:
A: Changes in Mediterranean diet scale (6, 12, and 24 months)
B: Physical Activity (Measured 5 times over 13 months, for seven days each time. Time points = baseline, 1-2weeks, 3 months, 6 months and 12 months)
C: Weight Loss (1 year)
D: Change in employer practices in health benefits, policies and programs (15 month follow-up survey)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: The Influence of Sit-stand Workstations Upon Total Physical Activity: a 12 Month Randomised Controlled Trial
Brief Summary: The purpose of this study is to examine the contribution of sit-stand workstations to total daily physical activity in a multi-component office-based 12 month intervention.


Options:
A: Mean Change in Light-intensity Physical Activity at Work From Baseline to 12 Months (1 year); Mean Change in Sitting Time at Work From Baseline to 12 Months (1 year)
B: Average steps per day (6 weeks)
C: non-exercise activity (Measured constantly during the entire control period and measured constantly during the entire intervention period and the two periods were compared to determine change in non-exercise activity)
D: Physical Activity (Measured 5 times over 13 months, for seven days each time. Time points = baseline, 1-2weeks, 3 months, 6 months and 12 months)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Evaluation of a Patient-Centered Medication Therapy Management Intervention to Reduce Inappropriate Anticholinergic Prescribing in the Elderly
Brief Summary: This will be an eight-week, prospective, placebo-controlled, randomized trial to evaluate a patient-centered team (pharmacist-physician) intervention to improve medication appropriateness and reduce the use of inappropriate anticholinergic medications in elderly patients enrolled in the Sanders-Brown Alzheimer's Disease Center (ADC) cohort.


Options:
A: Change in appropriateness of anticholinergic medication prescribing practices. (Two years)
B: Proportion of older ED patients who receive a potentially inappropriate medication (During discharge home from the ED)
C: N/A
D: Health-related quality of life as measured with 15D (16 weeks)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Evaluation of a Patient-Centered Medication Therapy Management Intervention to Reduce Inappropriate Anticholinergic Prescribing in the Elderly
Brief Summary: This will be an eight-week, prospective, placebo-controlled, randomized trial to evaluate a patient-centered team (pharmacist-physician) intervention to improve medication appropriateness and reduce the use of inappropriate anticholinergic medications in elderly patients enrolled in the Sanders-Brown Alzheimer's Disease Center (ADC) cohort.


Options:
A: Successful medication discontinuation (4 months)
B: Total standardized daily dose (TSDD) - from medical records (12 months); Total standardized daily dose (TSDD) - self-report medication inventory (12 months)
C: Change From Baseline to End of Treatment (EOT) in Mean Number of Micturitions Per 24 Hours (Baseline and EOT (up to 12 weeks)); Change From Baseline to EOT in Mean Number of Incontinence Episodes Per 24 Hours (Baseline and EOT (up to 12 weeks))
D: Change in appropriateness of anticholinergic medication prescribing practices. (Two years)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Ensayo clínico Comparando Recuperación Postoperatoria Tras Protocolo FAST- TRACK Vs. Manejo Clásico en Cáncer de Ovario Avanzado
Brief Summary: The concept of Fast-trak or Enhanced Recovery After Surgery ( ERAS) represents a new approach to the management of patients undergoing major surgery that re-examine traditional practices, replacing them if necessary with the best evidence based practices, creating a multimodal perioperative care pathway designed to achieve early recovery. In Colorectal Cancer Surgery , as well as in a number of other procedures it has been shown to reduce Hospitalization by more than 30% without increasing the rate complications or readmissions.

However information on the results of Fast-track protocols when applied to Gynecological patients is sparse, being especially notorious the lack of data regarding the efficacy of Fast-track in the management of Advanced Gynecological cancer.

Hypothesis: the application of a Fast-Track protocol in the management of patients with advanced Ovarian Cancer( Stage III, IV and relapses) may improve the postoperatory recovery of these patients allowing for an early discharge and significant cost reduction, when compared with de usual management, without increasing the number readmission or surgery related complications.


Options:
A: Shorter Length Of Hospitalization (LOH) (Up to 4 weeks after surgery)
B: median length of stay (participants will be followed for the duration of hospital stay, an expected average of 2 weeks.)
C: Hospital Stay (1 Month)
D: Length of Hospitalization Post-operation (up to 12 months); The Total Cost (RMB) (12 month)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Integrated Care for Inflammatory Bowel Disease Patients in the Netherlands With the Novel Telemedicine Tool myIBDcoach: a Randomized Controlled Trial
Brief Summary: Inflammatory bowel diseases (IBD) is an invalidating disease mainly diagnosed in young people. The disease is characterized by a heterogenic phenotype and the disease course by flares and remissions. As in most chronic diseases the economic burden of IBD is important due to direct health care costs and disability. Health care reorganization for IBD patients in the Netherlands is necessary for several reasons. First chronic (sub)clinical mucosal inflammation results in irreversible bowel damage and complications and none of the presently available drugs is effective for all patients and many drugs have possible severe side effects. To prevent complications of the disease and side effects IBD should be monitored carefully. In the Netherlands however there is a shortage of gastroenterologists where the incidence of IBD is rising. Secondly evidence exists that direct involvement of health care workers, patient empowerment and integrated care can improve the outcome of chronic diseases. Thirdly many clinically relevant aspects (e.g. malnutrition) of this complex disease are not systematically followed in routine care. Finally the government demands registration of efficacy endpoints for expensive drugs in the near future. Therefore the investigators developed a web-based Telemedicine tool for IBD patients in collaboration with the Dutch IBD patient's organization (CCUVN). "myIBcoach" contains E-learning modules, monitors disease activity, disability, quality of life, adherence, infections, smoking status, side effects, stress and malnutrition on fixed time points with validated questionnaires, allows the patient to communicate with health care workers and gives feedback to the back office and the patient. A feasibility study in 30 IBD patients in 3 centres showed a high satisfaction and compliance of IBD-patients and health care workers with this telemedicine tool.

The aim of this study is to compare standard care for IBD patients in 3 hospitals with a care via the telemedicine tool myIBDcoach.


Options:
A: Adherence (beginning at baseline - week 20)
B: Changes in the paediatric IBD-specific health-related quality of life (QOL) scores. (6 monthly over 2 years)
C: Clinical Remission (6 months); Clinical Remission (6 months)
D: Outpatient hospital visits (1 year); Satisfaction (1 year)

Answer: D
Please select the outcome measures that correspond to the clinical trial below.
Title: Integrated Care for Inflammatory Bowel Disease Patients in the Netherlands With the Novel Telemedicine Tool myIBDcoach: a Randomized Controlled Trial
Brief Summary: Inflammatory bowel diseases (IBD) is an invalidating disease mainly diagnosed in young people. The disease is characterized by a heterogenic phenotype and the disease course by flares and remissions. As in most chronic diseases the economic burden of IBD is important due to direct health care costs and disability. Health care reorganization for IBD patients in the Netherlands is necessary for several reasons. First chronic (sub)clinical mucosal inflammation results in irreversible bowel damage and complications and none of the presently available drugs is effective for all patients and many drugs have possible severe side effects. To prevent complications of the disease and side effects IBD should be monitored carefully. In the Netherlands however there is a shortage of gastroenterologists where the incidence of IBD is rising. Secondly evidence exists that direct involvement of health care workers, patient empowerment and integrated care can improve the outcome of chronic diseases. Thirdly many clinically relevant aspects (e.g. malnutrition) of this complex disease are not systematically followed in routine care. Finally the government demands registration of efficacy endpoints for expensive drugs in the near future. Therefore the investigators developed a web-based Telemedicine tool for IBD patients in collaboration with the Dutch IBD patient's organization (CCUVN). "myIBcoach" contains E-learning modules, monitors disease activity, disability, quality of life, adherence, infections, smoking status, side effects, stress and malnutrition on fixed time points with validated questionnaires, allows the patient to communicate with health care workers and gives feedback to the back office and the patient. A feasibility study in 30 IBD patients in 3 centres showed a high satisfaction and compliance of IBD-patients and health care workers with this telemedicine tool.

The aim of this study is to compare standard care for IBD patients in 3 hospitals with a care via the telemedicine tool myIBDcoach.


Options:
A: Outpatient hospital visits (1 year); Satisfaction (1 year)
B: Improvement in Quality Indicators (adapted from the American Gastroenterological Association (AGA) outpatient IBD quality metrics and other consensus recommendations) (up to 2 years)
C: Overall length of stay (1 year); Percentage of patients undergoing colectomy (1 year)
D: Harvey Bradshaw Index (12 months); Inflammatory Bowel Disease Questionnaire (12 months)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Study on the Effectiveness of Occupational Therapy Intervention in Complex Patients.
Brief Summary: To date, there are no studies that demonstrate that the intervention of Occupational Therapy (OT) in patients considered to be complex, regardless of diagnosis, could improve clinical and functional outcome for the patient.

For this reason, we intend to undertake a study that will allow us to deepen the knowledge about the impact of the OT on in-hospital patients considered "complex" according to the assessment by the Rehabilitation Complexity Scale (RCS ).

Our hypothesis is that the intervention of OT can improve their care by qualified and focused on the needs of the person interventions.


Options:
A: Paced auditory Serial Attention Test (PASAT) (change from baseline after each 3 treatment sessions, change from baseline after 20 hours of training, change from baseline after 6 months and change from baseline after 1 year); Work Ability Index (WAI) (change from baseline after 20 hours of training, change from baseline after 3 months and change from baseline after 1 year)
B: Conners Continuous Performance Test (CPT-II) (1 day); Rey Auditory Verbal Learning Test (RAVLT) (1 day); Spanish phonemic fluency test- PMR (1 day); Digit Span forward Subtest from the Wechsler Adult Intelligence Scale (WAIS-III) (1 day); Digit Span backward Subtest from the Wechsler Adult Intelligence Scale (WAIS-III) (1 day); Letter-Number Sequencing Subtest from the Wechsler Adult Intelligence Scale (WAIS-III) (1 day); Rating Scale for Attentional Behavior (RSAB) (1 week); Prospective and Retrospective Memory Questionnaire (PRMQ) (1 week); Behavior Rating Inventory of Executive Function-Adult Version (BRIEF-A) (1 week)
C: Canadian Occupational Performance Measure (COPM) (enrollment)
D: Motor impairment of the upper limb (Change from Baseline in motor impairment of the upper limb at 4 weeks)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Role of Midodrine and Tolvaptan in Patients With Cirrhosis With Refractory or Recurrent Ascites
Brief Summary: The development of ascites in the natural history of cirrhosis heralds a worsening of the prognosis to 50% survival at 2 years, and this deteriorates to 30-50% at 1 year when the ascites becomes refractory to medical therapy. Hemodynamic alterations and their relation to neurohumoral systems are essential in pathophysiology of ascites formation. The theory that best explain the ascites formation and sodium retention in cirrhotics is portal hypertension leading to splanchnic arterial vasodilatation leading to underfilling of arterial circulation which is sensed by the arterial and the cardiopulmonary receptors leading to sympathetic nervous system activation and activation of the anti-natriuretic factors (RAAS and arginine vasopressin), resulting in sodium and water retention. The therapeutic options available for patients with refractory ascites are serial therapeutic paracentesis, liver transplantation and transjugular intrahepatic portosystemic shunts.Vasopressin V2 receptor antagonists antagonize the antidiuretic effects of vasopressin at the V2 receptor located in the renal collecting duct, they increase free water clearance, and thus may be helpful in mobilizing excess water in conditions associated with water retention including cirrhosis. The use of V2 receptor antagonists in cirrhosis with ascites has been shown to be safe and efficacious. Midodrine, an alpha adreno receptor agonist by causing splanchnic vasoconstriction has been used in hepatorenal syndrome (HRS) and for control of ascites in patients with refractory or recurrent ascites. It is possible that vasoconstrictors and aquaretics (V2 receptor antagonists) by acting at different sites in combination may reverse some of the pathogenic events that results in refractory or recurrent ascites.There are no reports on the use of combination of midodrine and tolvaptan in the patients with cirrhosis with ascites. Therefore, we plan to study the role of midodrine, tolvaptan and their combination on systemic hemodynamics, renal functions and control of ascites in patients with cirrhosis and refractory or recurrent ascites.


Options:
A: Mortality (18 months)
B: Time to Recurrence of Ascites. (Variable depending on the patient, average 10 days)
C: Number of patients with control of ascites (3 months)
D: Survival at one year (one year)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: An Educational Intervention to Improve the Use of Antibiotics in Portuguese Health Professional: Cluster-randomized Trial
Brief Summary: This is a cluster randomised controlled trial covering all general practitioners working in the National Health System (SNS) and all pharmacists working in community pharmacies in the area covered by the Health Region Administration of Center (ARS-C) . A specific educative intervention, designed from gaps detected in knowledge and attitudes with respect to antibiotics and resistance, will be carried out on the intervention group. The control group will not receive any specific intervention.

Hypotheses:

1. The attitudes and knowledge towards antibiotics generate habits of prescription by physicians
2. The attitudes and knowledge towards to antibiotics generate propensity to dispense antibiotics without prescription by pharmacists
3. The identification of the attitudes, knowledge and factors that generate habits of inadequate prescription will allow the design of specific educative interventions to improve the use of antibiotics
4. The identification of the attitudes, knowledge and factors that generate propensity to dispense antibiotics without prescription will allow the design of specific educative interventions to antibiotic use
5. The interventions designed from gaps detected in knowledge and attitudes with respect to antibiotics and resistance will improve the prescription and dispensation of antibiotics by physicians and pharmacists, respectively.
6. The intervention will collaborate in the control of the bacterial resistance.


Options:
A: Proportion of febrile patients receiving treatment as recommended in clinical guidelines for uncomplicated malaria (As patients exit the health facility)
B: General practitioners'adherence to treatment recommendations (3-6 months after end of intervention)
C: Episiotomies; Oxytocin use in third stage of labor
D: Change From Baseline Antibiotic Consumption at 18 Months, in Primary Care (up to 18 months); Antibiotic Monthly Sales Data and Quality Indicators Monthly Prescribing Rates. (May 2012- September 2014)

Answer: D