Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized, Double-Blind (Sponsor Open), Placebo Controlled, Dose Escalating, Parallel Group, Multi-Centre Study To Investigate The Safety, Toleration, Pharmacokinetics And Pharmacodynamics Of Single And Multiple Intravenous/Sub-Cutaneous Doses Of PF-00547659 In Patients With Active Ulcerative Colitis.
Brief Summary: study to investigate the safety and efficacy properties of PF-00547659 in patients with active ulcerative colitis


Options:
A: Arm Label: Abatacept (ABA); Type: EXPERIMENTAL; Interventions: Drug: abatacept (ABA) | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Arm Label: abatacept; Type: OTHER; Interventions: Drug: abatacept | Intervention Type: DRUG; Name: abatacept (ABA); Assigned to Arm(s): Abatacept (ABA) | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Placebo | Intervention Type: DRUG; Name: abatacept; Assigned to Arm(s): abatacept
B: Arm Label: Vedolizumab; Type: EXPERIMENTAL; Interventions: Drug: vedolizumab | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Intervention Type: DRUG; Name: vedolizumab; Assigned to Arm(s): Vedolizumab | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Placebo
C: Arm Label: Mesalamin; Type: EXPERIMENTAL; Interventions: Drug: Mesalamin | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Mesalamin | Intervention Type: DRUG; Name: Mesalamin; Assigned to Arm(s): Mesalamin, Placebo
D: Arm Label: 0.03 mg/kg or placebo iv; Type: OTHER; Interventions: Biological: Single dose-group A | Arm Label: 0.1 mg/kg or placebo iv; Type: OTHER; Interventions: Biological: Single dose-group A, Biological: Multiple dose- Group B | Arm Label: 0.3 mg/kg or placebo iv; Type: OTHER; Interventions: Biological: Single dose-group A, Biological: Multiple dose- Group B | Arm Label: 1.0 mg/kg or placebo iv; Type: EXPERIMENTAL; Interventions: Biological: Single dose-group A | Arm Label: 3.0 mg/kg or placebo sc; Type: OTHER; Interventions: Biological: Single dose-group A | Arm Label: 10 mg/kg or placebo iv; Type: OTHER; Interventions: Biological: Single dose-group A | Arm Label: 0.3 mg/kg or placebo sc; Type: OTHER; Interventions: Biological: Single dose-group A, Biological: Multiple dose-Group B | Arm Label: 0.1 mg/kg or placebo iv (multiple dose); Type: OTHER; Interventions: Biological: Multiple dose- Group B | Arm Label: 0.3 mg/kg or placebo iv (multiple dose); Type: OTHER; Interventions: Biological: Multiple dose- Group B | Arm Label: 3.0 mg/kg or placebo iv; Type: OTHER; Interventions: Biological: Multiple dose- Group B | Arm Label: 0.1 mg/kg or placebo sc; Type: OTHER; Interventions: Biological: Multiple dose- Group B | Arm Label: 0.3 mg/kg or placebo sc (multiple dose); Type: OTHER; Interventions: Biological: Multiple dose-Group B | Intervention Type: BIOLOGICAL; Name: Single dose-group A; Assigned to Arm(s): 0.03 mg/kg or placebo iv | Intervention Type: BIOLOGICAL; Name: Single dose-group A; Assigned to Arm(s): 0.1 mg/kg or placebo iv | Intervention Type: BIOLOGICAL; Name: Multiple dose- Group B; Assigned to Arm(s): 0.1 mg/kg or placebo iv (multiple dose) | Intervention Type: BIOLOGICAL; Name: Single dose-group A; Assigned to Arm(s): 0.3 mg/kg or placebo iv | Intervention Type: BIOLOGICAL; Name: Multiple dose- Group B; Assigned to Arm(s): 0.3 mg/kg or placebo iv (multiple dose) | Intervention Type: BIOLOGICAL; Name: Single dose-group A; Assigned to Arm(s): 1.0 mg/kg or placebo iv | Intervention Type: BIOLOGICAL; Name: Single dose-group A; Assigned to Arm(s): 3.0 mg/kg or placebo sc | Intervention Type: BIOLOGICAL; Name: Single dose-group A; Assigned to Arm(s): 10 mg/kg or placebo iv | Intervention Type: BIOLOGICAL; Name: Single dose-group A; Assigned to Arm(s): 0.3 mg/kg or placebo sc | Intervention Type: BIOLOGICAL; Name: Multiple dose-Group B; Assigned to Arm(s): 0.3 mg/kg or placebo sc | Intervention Type: BIOLOGICAL; Name: Multiple dose- Group B; Assigned to Arm(s): 0.1 mg/kg or placebo iv | Intervention Type: BIOLOGICAL; Name: Multiple dose- Group B; Assigned to Arm(s): 0.3 mg/kg or placebo iv | Intervention Type: BIOLOGICAL; Name: Multiple dose- Group B; Assigned to Arm(s): 3.0 mg/kg or placebo iv | Intervention Type: BIOLOGICAL; Name: Multiple dose- Group B; Assigned to Arm(s): 0.1 mg/kg or placebo sc | Intervention Type: BIOLOGICAL; Name: Multiple dose-Group B; Assigned to Arm(s): 0.3 mg/kg or placebo sc (multiple dose)

Answer: D