TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Standard vs. Washed Blood Cell Transfusions in Pediatric Cardiac Surgery: Impact on Post-operative Inflammation as Evidenced by the IL-6 to IL-10 Ratio.
Brief Summary: Background: Children having open heart surgery to repair congenital heart defects demonstrate a large inflammatory response to the heart-lung machine and to surgery itself. In general, the more intense their inflammatory response, the more critically ill they are following surgery. These children routinely require large numbers of blood transfusions during and following surgery as part of their medical management that adds to their heightened inflammatory state. Whether additional steps to "wash" blood products and remove the substances contributing to post-transfusion inflammation will limit this response, and improve the health of children following open heart surgery, remains to be studied.

Aims: To compare the inflammatory response in children having open heart surgery who receive washed versus unwashed blood transfusions.

Methods: We will randomly assign children having open heart surgery to one of two groups: group 1 will receive blood transfusions per the current standard of care, group 2 will receive blood transfusions that have been washed in addition to the current standard of care. We will then use blood tests to measure the inflammatory response in children of each group. We will compare the results to determine whether washing blood transfusions decreases inflammation and post-operative complications following open heart surgery.

Conclusion: We believe that washing blood transfusions given to children following open heart surgery will decrease their inflammatory response and improve their overall health.


Options:
A: Arm Label: Shorter-storage red blood cell units; Type: ACTIVE_COMPARATOR; Interventions: Biological: Red blood cell units stored <= 10 days | Arm Label: Longer-storage red blood cell units; Type: ACTIVE_COMPARATOR; Interventions: Biological: Red blood cell units stored >= 21 days | Intervention Type: BIOLOGICAL; Name: Red blood cell units stored <= 10 days; Assigned to Arm(s): Shorter-storage red blood cell units | Intervention Type: BIOLOGICAL; Name: Red blood cell units stored >= 21 days; Assigned to Arm(s): Longer-storage red blood cell units
B: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Biological: Standard leukoreduced irradiated blood cell transfusion | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Biological: Washed leukoreduced irradiated blood cell transfusions | Intervention Type: BIOLOGICAL; Name: Standard leukoreduced irradiated blood cell transfusion; Assigned to Arm(s): 1 | Intervention Type: BIOLOGICAL; Name: Washed leukoreduced irradiated blood cell transfusions; Assigned to Arm(s): 2
C: Intervention Type: PROCEDURE; Name: Red blood cell transfusion; Assigned to Arm(s): N/A
D: Intervention Type: PROCEDURE; Name: Cardiopulmonary Bypass with Two Different Intra-Operative Hematocrits; Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: Thoracic Surgery; Assigned to Arm(s): N/A

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Controlled Comparative Study of the Efficacy of SARNA Sensitive Lotion for Treatment of Uremic Pruritus in Adult Hemodialysis Patients
Brief Summary: The purpose of this research study is to evaluate the efficacy of SARNA Sensitive Lotion in the treatment of uremic pruritus in adult hemodialysis patients in a double-blind Controlled comparative trial.


Options:
A: Arm Label: CR845 0.5mcg/kg; Type: ACTIVE_COMPARATOR; Interventions: Drug: CR845 0.5 mcg/kg | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: CR845 0.5 mcg/kg; Assigned to Arm(s): CR845 0.5mcg/kg | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
B: Arm Label: Sarna Lotion; Type: EXPERIMENTAL; Interventions: Drug: Sarna | Arm Label: Placebo Cetaphil lotion; Type: PLACEBO_COMPARATOR; Interventions: Drug: Cetaphil | Intervention Type: DRUG; Name: Sarna; Assigned to Arm(s): Sarna Lotion | Intervention Type: DRUG; Name: Cetaphil; Assigned to Arm(s): Placebo Cetaphil lotion
C: Arm Label: CR845 0.5mcg/kg; Type: ACTIVE_COMPARATOR; Interventions: Drug: CR845 0.5 mcg/kg | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: CR845 0.5 mcg/kg; Assigned to Arm(s): CR845 0.5mcg/kg | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
D: Arm Label: a treatment group; Type: EXPERIMENTAL; Interventions: Drug: PG102P | Arm Label: a control group; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: PG102P; Assigned to Arm(s): a treatment group | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): a control group

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: International Study to Predict Optimised Treatment - in Depression
Brief Summary: The aim of this study is to identify genetic, physical (brain) and psychological (cognitive) markers (or combinations of them) that predict specific response to a range of antidepressants treatment (Escitalopram, Venlafaxine, Sertraline) in patients diagnosed with major depressive disorder. This study is focused on outcomes which may impact on how "personalised medicine" is implemented in depression.


Options:
A: Intervention Type: DRUG; Name: Ebixa (memantine hydrochloride); Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Cipralex (escitalopram); Assigned to Arm(s): N/A
B: Arm Label: Sertraline; Type: EXPERIMENTAL; Interventions: Drug: sertraline (Zoloft) | Arm Label: Naltrexone; Type: EXPERIMENTAL; Interventions: Drug: naltrexone (Revia) | Arm Label: Nal/Sert; Type: EXPERIMENTAL; Interventions: Drug: naltrexone (Revia), Drug: sertraline (Zoloft) | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: naltrexone (Revia); Assigned to Arm(s): Nal/Sert, Naltrexone | Intervention Type: DRUG; Name: sertraline (Zoloft); Assigned to Arm(s): Nal/Sert, Sertraline | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
C: Arm Label: Escitalopram plus acamprosate; Type: EXPERIMENTAL; Interventions: Drug: acamprosate, Drug: escitalopram, Behavioral: Medical management | Arm Label: Escitalopram plus placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: escitalopram, Behavioral: Medical management, Drug: Placebo | Intervention Type: DRUG; Name: acamprosate; Assigned to Arm(s): Escitalopram plus acamprosate | Intervention Type: DRUG; Name: escitalopram; Assigned to Arm(s): Escitalopram plus acamprosate, Escitalopram plus placebo | Intervention Type: BEHAVIORAL; Name: Medical management; Assigned to Arm(s): Escitalopram plus acamprosate, Escitalopram plus placebo | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Escitalopram plus placebo
D: Arm Label: A; Type: ACTIVE_COMPARATOR; Interventions: Drug: Escitalopram | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Drug: Sertraline | Arm Label: C; Type: ACTIVE_COMPARATOR; Interventions: Drug: Venlafaxine-XR | Arm Label: D; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: Escitalopram; Assigned to Arm(s): A | Intervention Type: DRUG; Name: Sertraline; Assigned to Arm(s): B | Intervention Type: DRUG; Name: Venlafaxine-XR; Assigned to Arm(s): C

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Incidence of Intra-Operative Awareness in China and Analysis of Relevant Factors: a Multicentre Study
Brief Summary: Medical literature about awareness during general anesthesia is rare in China, and some small sampled studies in China showed a significantly higher incidence (1.5～6%) of intra-operative awareness compared with western countries. The investigators sponsored this multicenter, large sampled, prospective study to determine the incidence of intra-operative awareness in China, and the preservation effect of BIS monitor on the incidence of awareness.


Options:
A: Arm Label: BIS Monitor guided algorithm; Type: EXPERIMENTAL; Interventions: Device: BIS Monitor guided algorithm | Arm Label: Volatile anesthetic guided algorithm; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Volatile anesthetic guided algorithm | Intervention Type: DEVICE; Name: BIS Monitor guided algorithm; Assigned to Arm(s): BIS Monitor guided algorithm | Intervention Type: BEHAVIORAL; Name: Volatile anesthetic guided algorithm; Assigned to Arm(s): Volatile anesthetic guided algorithm
B: Arm Label: anesthesia monitoring; Type: EXPERIMENTAL; Interventions: Device: bispectral index monitoring | Arm Label: no bispectral index monitoring; Type: EXPERIMENTAL; Interventions: Device: bispectral index monitoring | Intervention Type: DEVICE; Name: bispectral index monitoring; Assigned to Arm(s): anesthesia monitoring, no bispectral index monitoring
C: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Bispectral index protocol | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: End tidal anesthetic gas-guided | Intervention Type: BEHAVIORAL; Name: Bispectral index protocol; Assigned to Arm(s): 1 | Intervention Type: BEHAVIORAL; Name: End tidal anesthetic gas-guided; Assigned to Arm(s): 2
D: N/A

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Increasing Activity in Peripheral Arterial Disease
Brief Summary: Lower extremity peripheral arterial disease (PAD) is a disease in which fatty build-up, or plaque, accumulates in the arteries of the legs. People with lower extremity PAD often experience leg pain while walking, which is caused by reduced blood flow to the legs. Regular walking has significant benefits for people with blood flow problems in their legs, but previous studies have shown that most men and women with PAD do not walk for exercise on a regular basis. A group home-based walking program may help people with PAD to walk more often and improve their lower extremity functioning. This study will evaluate the effectiveness of a home-based group mediated cognitive behavioral (GMCB) exercise program in helping people with lower extremity PAD to increase their walking frequency and improve their lower leg functioning.


Options:
A: Arm Label: AIT: aerobic interval training; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Aerobic interval training | Arm Label: MIT, moderate intensity training; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: moderate intensity training | Arm Label: Recommendation of regular exercise; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Recommendation of regular exercise | Intervention Type: BEHAVIORAL; Name: Aerobic interval training; Assigned to Arm(s): AIT: aerobic interval training | Intervention Type: BEHAVIORAL; Name: moderate intensity training; Assigned to Arm(s): MIT, moderate intensity training | Intervention Type: BEHAVIORAL; Name: Recommendation of regular exercise; Assigned to Arm(s): Recommendation of regular exercise
B: Arm Label: Intensive exercise; Type: EXPERIMENTAL; Interventions: Other: Intensive exercise | Arm Label: Lifestyle counseling; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Regular exercise; Type: EXPERIMENTAL; Interventions: Other: Conventional exercise | Intervention Type: OTHER; Name: Intensive exercise; Assigned to Arm(s): Intensive exercise | Intervention Type: OTHER; Name: Conventional exercise; Assigned to Arm(s): Regular exercise
C: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Group mediated cognitive behavioral (GMCB) sessions | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Other: Health education sessions | Intervention Type: BEHAVIORAL; Name: Group mediated cognitive behavioral (GMCB) sessions; Assigned to Arm(s): 1 | Intervention Type: OTHER; Name: Health education sessions; Assigned to Arm(s): 2
D: Arm Label: Exercise training; Type: EXPERIMENTAL; Interventions: Behavioral: Exercise training for 6 months | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Exercise training for 6 months; Assigned to Arm(s): Exercise training

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Increasing Activity in Peripheral Arterial Disease
Brief Summary: Lower extremity peripheral arterial disease (PAD) is a disease in which fatty build-up, or plaque, accumulates in the arteries of the legs. People with lower extremity PAD often experience leg pain while walking, which is caused by reduced blood flow to the legs. Regular walking has significant benefits for people with blood flow problems in their legs, but previous studies have shown that most men and women with PAD do not walk for exercise on a regular basis. A group home-based walking program may help people with PAD to walk more often and improve their lower extremity functioning. This study will evaluate the effectiveness of a home-based group mediated cognitive behavioral (GMCB) exercise program in helping people with lower extremity PAD to increase their walking frequency and improve their lower leg functioning.


Options:
A: Intervention Type: PROCEDURE; Name: Exercise therapy; Assigned to Arm(s): N/A | Intervention Type: DEVICE; Name: Accelerometer (PAM; Personal Activity Monitor); Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: Oral Exercise Therapy advise; Assigned to Arm(s): N/A
B: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Group mediated cognitive behavioral (GMCB) sessions | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Other: Health education sessions | Intervention Type: BEHAVIORAL; Name: Group mediated cognitive behavioral (GMCB) sessions; Assigned to Arm(s): 1 | Intervention Type: OTHER; Name: Health education sessions; Assigned to Arm(s): 2
C: Arm Label: Best medical treatment; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Supervised exercise training; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Supervised exercise training | Intervention Type: BEHAVIORAL; Name: Supervised exercise training; Assigned to Arm(s): Supervised exercise training
D: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Supervised Exercise Therapy, Drug: Cilostazol | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Device: Stent, Drug: Cilostazol | Arm Label: 3; Type: ACTIVE_COMPARATOR; Interventions: Device: Stent, Behavioral: Supervised Exercise Therapy | Intervention Type: DEVICE; Name: Stent; Assigned to Arm(s): 2, 3 | Intervention Type: BEHAVIORAL; Name: Supervised Exercise Therapy; Assigned to Arm(s): 1, 3 | Intervention Type: DRUG; Name: Cilostazol; Assigned to Arm(s): 1, 2

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Increasing Activity in Peripheral Arterial Disease
Brief Summary: Lower extremity peripheral arterial disease (PAD) is a disease in which fatty build-up, or plaque, accumulates in the arteries of the legs. People with lower extremity PAD often experience leg pain while walking, which is caused by reduced blood flow to the legs. Regular walking has significant benefits for people with blood flow problems in their legs, but previous studies have shown that most men and women with PAD do not walk for exercise on a regular basis. A group home-based walking program may help people with PAD to walk more often and improve their lower extremity functioning. This study will evaluate the effectiveness of a home-based group mediated cognitive behavioral (GMCB) exercise program in helping people with lower extremity PAD to increase their walking frequency and improve their lower leg functioning.


Options:
A: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Walking Exercise | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Behavioral: Walking Exercise | Arm Label: 3; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Control--Resistance Training | Intervention Type: BEHAVIORAL; Name: Walking Exercise; Assigned to Arm(s): 1, 2 | Intervention Type: BEHAVIORAL; Name: Control--Resistance Training; Assigned to Arm(s): 3
B: Arm Label: Intermittent claudication; Type: N/A; Interventions: N/A
C: Arm Label: A: GM-CSF + supervised treadmill exercise therapy; Type: EXPERIMENTAL; Interventions: Behavioral: Supervised Treadmill Exercise Therapy, Drug: granulocyte macrophage colony stimulating factor (GM-CSF) | Arm Label: B: GM-CSF + attention control group; Type: ACTIVE_COMPARATOR; Interventions: Other: Health education sessions (Control), Drug: granulocyte macrophage colony stimulating factor (GM-CSF) | Arm Label: C: placebo + supervised exercise therapy; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Supervised Treadmill Exercise Therapy | Arm Label: D: placebo + attention control group; Type: PLACEBO_COMPARATOR; Interventions: Other: Health education sessions (Control) | Intervention Type: BEHAVIORAL; Name: Supervised Treadmill Exercise Therapy; Assigned to Arm(s): A: GM-CSF + supervised treadmill exercise therapy, C: placebo + supervised exercise therapy | Intervention Type: OTHER; Name: Health education sessions (Control); Assigned to Arm(s): B: GM-CSF + attention control group, D: placebo + attention control group | Intervention Type: DRUG; Name: granulocyte macrophage colony stimulating factor (GM-CSF); Assigned to Arm(s): A: GM-CSF + supervised treadmill exercise therapy, B: GM-CSF + attention control group
D: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Behavioral: Group mediated cognitive behavioral (GMCB) sessions | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Other: Health education sessions | Intervention Type: BEHAVIORAL; Name: Group mediated cognitive behavioral (GMCB) sessions; Assigned to Arm(s): 1 | Intervention Type: OTHER; Name: Health education sessions; Assigned to Arm(s): 2

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Veterans Walk to Beat Back Pain
Brief Summary: The objective of this study was to assess whether an Internet-mediated pedometer based intervention would increase walking and improve function among individuals with chronic back pain.


Options:
A: Arm Label: Education and Standard Care; Type: ACTIVE_COMPARATOR; Interventions: Other: Education and standard care | Arm Label: Internet Mediated Enhanced Pedometer; Type: EXPERIMENTAL; Interventions: Other: Education and standard care, Behavioral: Internet mediated enhanced pedometer intervention | Intervention Type: OTHER; Name: Education and standard care; Assigned to Arm(s): Education and Standard Care, Internet Mediated Enhanced Pedometer | Intervention Type: BEHAVIORAL; Name: Internet mediated enhanced pedometer intervention; Assigned to Arm(s): Internet Mediated Enhanced Pedometer
B: Arm Label: Motor Control Exercise Plus Patient Education; Type: EXPERIMENTAL; Interventions: Behavioral: Motor Control Exercise, Behavioral: Patient Education | Arm Label: Motor Control Exercise; Type: EXPERIMENTAL; Interventions: Behavioral: Motor Control Exercise | Arm Label: Patient Education; Type: EXPERIMENTAL; Interventions: Behavioral: Patient Education | Intervention Type: BEHAVIORAL; Name: Motor Control Exercise; Assigned to Arm(s): Motor Control Exercise, Motor Control Exercise Plus Patient Education | Intervention Type: BEHAVIORAL; Name: Patient Education; Assigned to Arm(s): Motor Control Exercise Plus Patient Education, Patient Education
C: Arm Label: Exercise and advise to stay active; Type: ACTIVE_COMPARATOR; Interventions: Other: Exercise | Arm Label: Rest and use of flexible lumbar belt; Type: EXPERIMENTAL; Interventions: Other: Restitution | Intervention Type: OTHER; Name: Exercise; Assigned to Arm(s): Exercise and advise to stay active | Intervention Type: OTHER; Name: Restitution; Assigned to Arm(s): Rest and use of flexible lumbar belt
D: Intervention Type: PROCEDURE; Name: Mod. functional restoration-Individ. dynamic back-muscle; Assigned to Arm(s): N/A

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Veterans Walk to Beat Back Pain
Brief Summary: The objective of this study was to assess whether an Internet-mediated pedometer based intervention would increase walking and improve function among individuals with chronic back pain.


Options:
A: Intervention Type: PROCEDURE; Name: management of therapy complications; Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: pain therapy; Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: psychosocial assessment and care; Assigned to Arm(s): N/A | Intervention Type: PROCEDURE; Name: quality-of-life assessment; Assigned to Arm(s): N/A
B: Arm Label: web page; Type: ACTIVE_COMPARATOR; Interventions: Other: Webpage | Arm Label: Webpage and situational feedback; Type: EXPERIMENTAL; Interventions: Other: Webpage and situation feedback | Intervention Type: OTHER; Name: Webpage; Assigned to Arm(s): web page | Intervention Type: OTHER; Name: Webpage and situation feedback; Assigned to Arm(s): Webpage and situational feedback
C: Arm Label: Education and Standard Care; Type: ACTIVE_COMPARATOR; Interventions: Other: Education and standard care | Arm Label: Internet Mediated Enhanced Pedometer; Type: EXPERIMENTAL; Interventions: Other: Education and standard care, Behavioral: Internet mediated enhanced pedometer intervention | Intervention Type: OTHER; Name: Education and standard care; Assigned to Arm(s): Education and Standard Care, Internet Mediated Enhanced Pedometer | Intervention Type: BEHAVIORAL; Name: Internet mediated enhanced pedometer intervention; Assigned to Arm(s): Internet Mediated Enhanced Pedometer
D: Arm Label: Core stabilization and psychosocial education; Type: EXPERIMENTAL; Interventions: Behavioral: Core stabilization and psychosocial education | Arm Label: Core stabilization exercise only; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Core stabilization exercise only | Arm Label: Psychosocial education class only.; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Psychosocial education class only | Arm Label: Traditional Army training; Type: OTHER; Interventions: Behavioral: Traditional Army training | Intervention Type: BEHAVIORAL; Name: Traditional Army training; Assigned to Arm(s): Traditional Army training | Intervention Type: BEHAVIORAL; Name: Core stabilization exercise only; Assigned to Arm(s): Core stabilization exercise only | Intervention Type: BEHAVIORAL; Name: Psychosocial education class only; Assigned to Arm(s): Psychosocial education class only. | Intervention Type: BEHAVIORAL; Name: Core stabilization and psychosocial education; Assigned to Arm(s): Core stabilization and psychosocial education

Answer: C