Please select the eligibility criteria that correspond to the clinical trial below.
Title: Effectiveness of Mirror Therapy in Patients With Amputations of Lower Limbs of Vascular Origin
Brief Summary: The aim of this study is to assess the efficacy of the mirror therapy on phantom pain for patients with amputation after vascular etiology. the secondary aim are to measure the impact of the mirror therapy on quality of life, sleep disorders, and predictive factors for effectiveness. the design is a prospective study, randomised, blindly evaluated, monocentric. There will be 2 groups: 1) rehabilitation and gabapentine; 2) rehabilitation and gabapentine + mirror therapy during the first 4 weeks. The assessment are going to be preformed at the inclusion day and then every 2 weeks during 8 weeks. the primary evaluation criterion will be the phantom pain measured on a VAS. the delay for inclusion is 18 months in order ton include 40 patients. The length of the study is 20 months.


Options:
A: Inclusion Criteria:

1. Pain in the stump area ≥ 3 months, no intermittent
2. Have three months elapsed amputation,
3. Submit subjective sensation of phantom limb not blinking

Exclusion Criteria:

* Clinical signs of radiculopathy.
* Lumbar stenosis, fibromyalgia, spondylolisthesis.
* History of spinal surgery.
* Corticosteroid therapy in the past two weeks.
* Disease of the central nervous system or peripheral.
B: Inclusion Criteria:

* Subjects must be unilateral transtibial amputees (TTA) between the ages of 18 and 65 who have consistently used a prosthesis for at least one year.
* Subjects must be community ambulators at a K3 level,

  * which dictates that they have the ability or potential to walk with variable cadence,
  * to traverse most environmental barriers and may have vocational, therapeutic, or exercise activity that demands prosthetic utilization beyond simple locomotion.

Exclusion Criteria:

* History of surgical procedures on their intact limb.
* Subjects will be excluded from the study if they present with

  * cardiovascular,
  * neurological,
  * or balance disorders that can affect gait.
  * Rheumatoid arthritis,
  * knee joint replacement,
  * and the use of ambulatory aids will also exclude participation.
* Subjects with considerable pain in their knee joints, as measured by a visual analog scale will also be excluded due to the confounding effects of pain on gait patterns.
* A medical history screening will be used to identify subjects with pre-existing conditions that would compromise their gait.
C: Inclusion Criteria:

* Unilateral or bilateral lower limb amputation at transtibial or transfemoral level
* Ability to wear and use a prosthesis
* Designated K-level 2 - 4, or equivalent
* Prescription of definitive prosthesis
* Veterans Affairs participants must receive care through the Veterans Affairs or related remote-site clinic
* Age: 18-89 years-to reflect the age range of eligible participants at Department of Defense and Veterans Affairs study sites, including young, combat-injured Service Members and healthy older Veterans, aged 70-80.

Exclusion Criteria:

* Co-morbidities that limit prosthesis use, independently of prosthetic function, training, or motivation, such as stroke, obesity, severe traumatic brain injury, and neuralgia, which require interventions outside the scope of this study. Suitability to participate in the study will be determined by the individual's physician.
* Unable or unwilling to learn to use the smartphone app or to allow transmission of study data
* Unable or unwilling to provide informed consent
* Residing in an area with poor cell phone coverage
D: Inclusion Criteria:

* Patient over 18 years of age who signed the memorandum.
* Patient hospitalized in the service for setting up equipment.
* In the aftermath of a major amputation of the lower limb, of vascular origin.
* Patients with phantom pain greater than or equal to 30 Visual Analog Evaluation (EVA); Whether pharmacologically or not.

Exclusion Criteria:

* Refusal to participate in the study.
* Presence of cognitive or psychiatric disorders that compromise the realization of mirror therapy.
* Presence of neurological, rheumatological or orthopedic disorders that may prevent movement of the unaffected limb.

Answer: D