Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Effect of Exercise Training on Cardiac Structure and Function
Brief Summary: Exercise training, as part of cardiac rehabilitation, is effective in improving functional capacity and quality of life in patients with coronary artery disease. Other cardiovascular and non-cardiovascular benefits have been reported, namely in glucose metabolism, skeletal muscle function, oxidative stress, vascular function, pulmonary circulation, ischaemia-reperfusion lesion and ventricular remodelling.

However, the benefit of exercise training on systolic and diastolic function is controversial especially after acute myocardial infarction where no longitudinal study has evaluated diastolic function using modern echocardiographic parameters.

The hypothesis is that a structured program of exercise training can improve systolic and diastolic function in patients after myocardial infarction.


Options:
A: Inclusion Criteria:

1. Men and women admitted for an IHD event (acute coronary syndrome or revascularization procedure) who are at low or moderate risk.91
2. Regular Internet access (home, work or other environment).
3. Over 18 years of age.
4. Permission of the attending physician.
5. Able to read, write and understand English without difficulty.
6. No physical limitations to regular activity.

Exclusion Criteria:

1. Previous experience with a cardiac rehabilitation program.
2. Patients with depression, uncontrolled diabetes and other significant co-morbidities that may interfere with effective IHD management.
3. Those patients, who in the mind of the attending physician, are unsuitable for participation.
4. Those unable to provide informed consent.
5. Pregnant women.
6. High-risk patients for safety considerations (future studies will include high-risk patients).
B: Inclusion Criteria:

* Successful PCI with stent implantation,
* Able to participate in the training program,
* No planned further revascularisation

Exclusion Criteria:

* CAGB,
* Inflammatory diseases other than CAD,
* Heart failure,
* Severe kidney failure,
* Inability to participate in the training program
C: Inclusion Criteria:

* Women and men
* Aged \>75 years
* Candidates to a 4-week
* In-Hospital comprehensive CR after ACS
* PCI
* Cardiac surgery

Exclusion Criteria:

* Any medical condition that would make physical exercise unsafe (unstable angina, sustained ventricular arrhythmias, AF with elevated ventricular response, symptomatic COPD, uncontrolled arterial hypertension, uncontrolled diabetes, hyperthyroidism) or that would limit physical capacity (severe anemia (Hb\<10 gr/dl), moderate-to-severe chronic renal failure (creatinine \>2.5 mg/dl), severe arthritis, peripheral artery disease (Fontaine \>IIb), metastatic cancer)
* Symptomatic (NYHA II-IV) chronic heart failure
* Moderate-to-severe left ventricular systolic dysfunction (left ventricular ejection fraction \<35%)
* BADL disability
* Denied informed consent
D: Inclusion Criteria:

* Patients one month after myocardial infarction
* Older 18 years

Exclusion Criteria:

* Age above 75 years,
* Inability to exercise,
* Hemodinamically significant valvular disease,
* Moderate to severe chronic lung disease (vital capacity and/or forced expiratory volume in 1 s \<80% of age-dependent predicted value),
* Atrial fibrillation
* Exercise induced myocardial ischemia
* Anaemia (haemoglobin \<12 g/dl).

Answer: D