Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Comparative Study of Influenza Vaccines in Adults - FLU-VACS
Brief Summary: The purpose of this study is to compare 2 licensed flu vaccines to each other and to placebo (inactive substance). The study will be conducted among healthy adult participants aged 18-49 years and is expected to last 3 years. During year 1, participants will be assigned to receive 1 of the 2 licensed flu vaccines or placebo, given as either nasal spray (live-attenuated vaccine or placebo) or injection (inactivated vaccine or placebo). Participants will receive the same assigned vaccine or placebo during year 2. During year 3, participants will be followed, but will not receive flu vaccine. Each year blood samples will be collected before and 1 month after each vaccination and at the end of each flu season in order to measure how the body responds to the vaccine and how well participants were protected from the flu. During the flu season, participants with flu-like illness will provide information on symptoms and provide a throat swab to test for virus identification.


Options:
A: Arm Label: A; Type: EXPERIMENTAL; Interventions: Biological: VAX125 | Intervention Type: BIOLOGICAL; Name: VAX125; Assigned to Arm(s): A
B: Arm Label: pandemic vaccine 1; Type: EXPERIMENTAL; Interventions: Biological: pandemic vaccine 1 | Arm Label: pandemic vaccine 2; Type: EXPERIMENTAL; Interventions: Biological: pandemic vaccine 2 | Arm Label: pandemic vaccine 5; Type: EXPERIMENTAL; Interventions: Biological: pandemic vaccine 5 | Arm Label: pandemic vaccine 6; Type: EXPERIMENTAL; Interventions: Biological: pandemic vaccine 6 | Arm Label: pandemic vaccine 9; Type: EXPERIMENTAL; Interventions: Biological: pandemic vaccine 9 | Arm Label: pandemic vaccine 10; Type: EXPERIMENTAL; Interventions: Biological: pandemic vaccine 10 | Arm Label: pandemic vaccine 11; Type: EXPERIMENTAL; Interventions: Biological: pandmeic vaccine 11 | Arm Label: pandemic vaccine 12; Type: EXPERIMENTAL; Interventions: Biological: pandmeic vaccine 12 | Arm Label: pandemic vaccine 13; Type: EXPERIMENTAL; Interventions: Biological: pandmic vaccine 13 | Arm Label: placebo group 14; Type: PLACEBO_COMPARATOR; Interventions: Biological: placebo group 14 | Intervention Type: BIOLOGICAL; Name: pandemic vaccine 1; Assigned to Arm(s): pandemic vaccine 1 | Intervention Type: BIOLOGICAL; Name: pandemic vaccine 2; Assigned to Arm(s): pandemic vaccine 2 | Intervention Type: BIOLOGICAL; Name: pandemic vaccine 5; Assigned to Arm(s): pandemic vaccine 5 | Intervention Type: BIOLOGICAL; Name: pandemic vaccine 6; Assigned to Arm(s): pandemic vaccine 6 | Intervention Type: BIOLOGICAL; Name: pandemic vaccine 9; Assigned to Arm(s): pandemic vaccine 9 | Intervention Type: BIOLOGICAL; Name: pandemic vaccine 10; Assigned to Arm(s): pandemic vaccine 10 | Intervention Type: BIOLOGICAL; Name: pandmeic vaccine 11; Assigned to Arm(s): pandemic vaccine 11 | Intervention Type: BIOLOGICAL; Name: pandmeic vaccine 12; Assigned to Arm(s): pandemic vaccine 12 | Intervention Type: BIOLOGICAL; Name: pandmic vaccine 13; Assigned to Arm(s): pandemic vaccine 13 | Intervention Type: BIOLOGICAL; Name: placebo group 14; Assigned to Arm(s): placebo group 14
C: Arm Label: Group 4: Placebo: Intramuscular; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Arm Label: Group 3: Placebo: Nasal; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Arm Label: Group 1: FluMist™; Type: EXPERIMENTAL; Interventions: Biological: Cold-adapted live attenuated influenza virus vaccine, trivalent | Arm Label: Group 2: Fluzone®/Fluvirin; Type: EXPERIMENTAL; Interventions: Biological: Trivalent inactivated influenza vaccine | Intervention Type: BIOLOGICAL; Name: Cold-adapted live attenuated influenza virus vaccine, trivalent; Assigned to Arm(s): Group 1: FluMist™ | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Group 4: Placebo: Intramuscular | Intervention Type: BIOLOGICAL; Name: Trivalent inactivated influenza vaccine; Assigned to Arm(s): Group 2: Fluzone®/Fluvirin | Intervention Type: BIOLOGICAL; Name: Trivalent inactivated influenza vaccine; Assigned to Arm(s): Group 2: Fluzone®/Fluvirin | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Group 3: Placebo: Nasal
D: Arm Label: split-virion, non-adjuvanted H1N1 vaccine of 15 μg; Type: EXPERIMENTAL; Interventions: Biological: split-virion, non-adjuvanted H1N1 vaccine of 15 μg | Intervention Type: BIOLOGICAL; Name: split-virion, non-adjuvanted H1N1 vaccine of 15 μg; Assigned to Arm(s): split-virion, non-adjuvanted H1N1 vaccine of 15 μg

Answer: C