Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Pseudo-randomised, Double-blinded Placebo-controlled Trial of Chloroquine or Sulphadoxine-pyrimethamine Alone or in Combination With Primaquine or Artesunate for the Treatment of Uncomplicated Falciparum Malaria in Pakistan
Brief Summary: This study is an evaluation of the benefit of adding artesunate to existing first and second line antimalarial therapies in Pakistan.

A placebo controlled trial was carried out to assess two potential benefits of Artesunate Combination Therapy (ACT): efficacy and potential for transmission reduction.


Options:
A: Arm Label: CQ; Type: EXPERIMENTAL; Interventions: Drug: Chloroquine (CQ) | Arm Label: CQ+PQ; Type: EXPERIMENTAL; Interventions: Drug: Chloroquine (CQ), Drug: primaquine (PQ) | Arm Label: CQ + AS; Type: EXPERIMENTAL; Interventions: Drug: artesunate (AS), Drug: Chloroquine (CQ) | Arm Label: SP; Type: EXPERIMENTAL; Interventions: Drug: sulphadoxine-pyrimethamine (SP) | Arm Label: SP + PQ; Type: EXPERIMENTAL; Interventions: Drug: sulphadoxine-pyrimethamine (SP), Drug: primaquine (PQ) | Arm Label: SP + AS; Type: EXPERIMENTAL; Interventions: Drug: artesunate (AS), Drug: sulphadoxine-pyrimethamine (SP) | Intervention Type: DRUG; Name: artesunate (AS); Assigned to Arm(s): CQ + AS, SP + AS | Intervention Type: DRUG; Name: sulphadoxine-pyrimethamine (SP); Assigned to Arm(s): SP, SP + AS, SP + PQ | Intervention Type: DRUG; Name: Chloroquine (CQ); Assigned to Arm(s): CQ, CQ + AS, CQ+PQ | Intervention Type: DRUG; Name: primaquine (PQ); Assigned to Arm(s): CQ+PQ, SP + PQ
B: Arm Label: dihydroartemisinin-piperaquine only; Type: ACTIVE_COMPARATOR; Interventions: Drug: dihydroartemisinin-piperaquine | Arm Label: DP and 0.125 mg/kg primaquine; Type: EXPERIMENTAL; Interventions: Drug: dihydroartemisinin-piperaquine, Drug: 0.125 mg/kg Primaquine | Arm Label: DP and 0.5 mg/kg primaquine; Type: EXPERIMENTAL; Interventions: Drug: dihydroartemisinin-piperaquine, Drug: 0.5 mg/kg Primaquine | Arm Label: DP and 0.25 mg/kg primaquine; Type: EXPERIMENTAL; Interventions: Drug: dihydroartemisinin-piperaquine, Drug: 0.25 mg/kg Primaquine | Arm Label: DP and 0.0625 mg/kg primaquine; Type: EXPERIMENTAL; Interventions: Drug: dihydroartemisinin-piperaquine, Drug: 0.0625 mg/kg Primaquine | Intervention Type: DRUG; Name: dihydroartemisinin-piperaquine; Assigned to Arm(s): DP and 0.0625 mg/kg primaquine, DP and 0.125 mg/kg primaquine, DP and 0.25 mg/kg primaquine, DP and 0.5 mg/kg primaquine, dihydroartemisinin-piperaquine only | Intervention Type: DRUG; Name: 0.125 mg/kg Primaquine; Assigned to Arm(s): DP and 0.125 mg/kg primaquine | Intervention Type: DRUG; Name: 0.5 mg/kg Primaquine; Assigned to Arm(s): DP and 0.5 mg/kg primaquine | Intervention Type: DRUG; Name: 0.25 mg/kg Primaquine; Assigned to Arm(s): DP and 0.25 mg/kg primaquine | Intervention Type: DRUG; Name: 0.0625 mg/kg Primaquine; Assigned to Arm(s): DP and 0.0625 mg/kg primaquine
C: Arm Label: Arm 1; Type: EXPERIMENTAL; Interventions: Drug: chlorproguanil-dapsone-artesunate, Drug: chlorproguanil-dapsone | Intervention Type: DRUG; Name: chlorproguanil-dapsone-artesunate; Assigned to Arm(s): Arm 1 | Intervention Type: DRUG; Name: chlorproguanil-dapsone; Assigned to Arm(s): Arm 1
D: Arm Label: dihydroartemisinin-piperaquine; Type: ACTIVE_COMPARATOR; Interventions: Drug: dihydroartemisinin-piperaquine | Arm Label: Dihydroartemisininpiperaquine primaquine; Type: ACTIVE_COMPARATOR; Interventions: Drug: dihydroartemisinin-piperaquine + primaquine | Intervention Type: DRUG; Name: dihydroartemisinin-piperaquine; Assigned to Arm(s): dihydroartemisinin-piperaquine | Intervention Type: DRUG; Name: dihydroartemisinin-piperaquine + primaquine; Assigned to Arm(s): Dihydroartemisininpiperaquine primaquine

Answer: A