TrialPanorama/Dataset huggingface dataset:
Please select the outcome measures that correspond to the clinical trial below.
Title: Simplified Tai Chi for Reducing Fibromyalgia Pain
Brief Summary: Data from two recent Tai chi studies have found that Tai Chi yields symptomatic benefit in patients with fibromyalgia (FM). The purpose of this study is to confirm those findings in a larger randomized, controlled clinical trial in a community-based setting. We also sought to extend this line of inquiry by closely examining Tai chi's effect on physical function, specifically postural stability. Towards these ends, we conducted a single-blind, randomized controlled clinical trial of an FM modified 8-form Yang-style Tai chi program compared to standard education. Subjects in both conditions meet in small groups two times weekly for 60 minutes over 12 weeks.


Options:
A: Fibromyalgia Impact Questionnaire (Assessed following 12 week intervention)
B: Decrease of pain and use of specific medicine for fibromyalgia (16 weeks)
C: Pain severity (Week 3)
D: The primary outcome measure will be the change in mean daily pain diary score from baseline (average pain score over 7 days pre-treatment) to the final week of Qigong treatment. (7 days)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Simplified Tai Chi for Reducing Fibromyalgia Pain
Brief Summary: Data from two recent Tai chi studies have found that Tai Chi yields symptomatic benefit in patients with fibromyalgia (FM). The purpose of this study is to confirm those findings in a larger randomized, controlled clinical trial in a community-based setting. We also sought to extend this line of inquiry by closely examining Tai chi's effect on physical function, specifically postural stability. Towards these ends, we conducted a single-blind, randomized controlled clinical trial of an FM modified 8-form Yang-style Tai chi program compared to standard education. Subjects in both conditions meet in small groups two times weekly for 60 minutes over 12 weeks.


Options:
A: Pain (10 sessions, in 5 weeks, 2 times a week)
B: Visual Analog Scale for Pain (baseline, after 16 weeks and after 32 weeks)
C: Fibromyalgia Impact Questionnaire (Assessed following 12 week intervention)
D: Muscle function (2010-2013)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Simplified Tai Chi for Reducing Fibromyalgia Pain
Brief Summary: Data from two recent Tai chi studies have found that Tai Chi yields symptomatic benefit in patients with fibromyalgia (FM). The purpose of this study is to confirm those findings in a larger randomized, controlled clinical trial in a community-based setting. We also sought to extend this line of inquiry by closely examining Tai chi's effect on physical function, specifically postural stability. Towards these ends, we conducted a single-blind, randomized controlled clinical trial of an FM modified 8-form Yang-style Tai chi program compared to standard education. Subjects in both conditions meet in small groups two times weekly for 60 minutes over 12 weeks.


Options:
A: Fibromyalgia Impact Questionnaire (Assessed following 12 week intervention)
B: The primary outcome measure will be the change in mean daily pain diary score from baseline (average pain score over 7 days pre-treatment) to the final week of Qigong treatment. (7 days)
C: Quality of life is measured with the FIQ and the EuroQol-5D. (1, 2, 6 and 12 months later)
D: Change in Weekly Average Pain Intensity (Baseline and Week 21clinic visits)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Effect of METOprolol in CARDioproteCtioN During an Acute Myocardial InfarCtion. The ME"Effect of METOprolol in CARDioproteCtioN During an Acute Myocardial InfarCtion" (METOCARD-CNIC): A Randomized, Controlled Parallel-group, Observer-blinded Clinical Trial of Early Pre-reperfusion Metoprolol Administration in ST-segment Elevation Myocardial infarctionTOCARD-CNIC Trial.
Brief Summary: The purpose of this study is to test whether early pre-reperfusion metoprolol administration in patients suffering and acute myocardial infarction might reduce the size of myocardial necrosis.


Options:
A: Infarct size evaluated primarily by area of delayed enhancement on cardiac magnetic resonance imaging. (5-7 days after reperfusion)
B: All cause mortality (6-year); Composite of death, myocardial infarction, acute coronary syndrome, heart failure hospitalization (6-year)
C: All causes mortality at each follow-up period (6 months, each year)
D: major cardiovascular events (defined as cardiovascular death, nonfatal myocardial infarction, or nonfatal cardiac arrest) (30 days)

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Enhancing Smoker Utilization of the Minnesota Quitline Through Support Persons
Brief Summary: This study will develop an intervention for adults who want to support a smoker. The goal of the intervention is for the support person to motivate \& encourage their smoker to call the state Quitline funded by Minnesota ClearWay. The study will examine the efficacy of a telephone based intervention for support persons compared to a self-help intervention (written materials only).


Options:
A: 7-day point prevalence abstinence (Measured at Months 3, 6, and 12)
B: proportion of smokers in each group who call the Minnesota Quitline, and changes in supportive behaviors among the support persons as measured by the Support Provided Measure. (6 months)
C: Biochemically-validated 7-day point prevalence tobacco abstinence at end of pregnancy
D: 7-Day Point Prevalence Abstinence From Smoking by Intervention (26 weeks after the target quit smoking date); 7-Day Point Prevalence Abstinence From Smoking by Nicotine Replacement Therapy (NRT) Group (26 weeks after the target quit smoking date)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Assessment of the Relationship Between Salivary Phosphorus and Level of Kidney Function
Brief Summary: The specific purpose of this study is to describe the relationship between salivary phosphorus and kidney function, specifically as it relates to serum phosphorus, FGF23, PTH, vitamin D status and urinary excretion of phosphorus.


Options:
A: Total phosphorus bound and entrapped per piece of chewing gum (60 minutes)
B: Correlation between fasting salivary phosphorus and estimated glomerular filtration rate (single value between 7-11 am); Correlation between post meal salivary phosphorus and estimated glomerular filtration rate (single value after meal between 1-4 pm)
C: FGF23 serum level (Change over 2 weeks of treatment)
D: Change in Serum Phosphorus Levels From Week 24 to Week 27 (Week 24, Week 27)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Assessment of the Relationship Between Salivary Phosphorus and Level of Kidney Function
Brief Summary: The specific purpose of this study is to describe the relationship between salivary phosphorus and kidney function, specifically as it relates to serum phosphorus, FGF23, PTH, vitamin D status and urinary excretion of phosphorus.


Options:
A: Calcium Balance (2 weeks)
B: To determine if the dietary protein source affects fasting serum and urinary phosphorus excretion in patients with CKD stages 3 and 4. (6 months after baseline)
C: Correlation between fasting salivary phosphorus and estimated glomerular filtration rate (single value between 7-11 am); Correlation between post meal salivary phosphorus and estimated glomerular filtration rate (single value after meal between 1-4 pm)
D: The change in plasma phosphorus after 8 weeks of niacinamide versus placebo (8 weeks)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Internet-Based Intervention to Improve Mental Health Outcomes for Abused Women
Brief Summary: The purpose for this trial is to test the effectiveness of the first interactive internet-based safety decision aid on abused women's exposure to repeat intimate partner violence (IPV) and mental health outcomes. An improved safety decision-making process (e.g., knowing the advantages and disadvantages of the relationship, having enough information to make a decision) will increase safety-seeking behaviors which in turn will decrease exposure to repeat IPV and improve mental health outcomes. Findings from the development and initial test of our computerized safety decision aid suggests that it offered abused women privacy to consider personalized safety options, informed them about danger in their relationship and would be used again if they had access to it through a safe internet site.

The investigators are conducting a five year experimental trial in four states (Oregon, Maryland, Missouri, and Arizona) to address the following aims:

1. Test the effectiveness of an interactive internet-based safety decision aid on abused women's safety seeking behaviors and exposure to violence compared to women assigned to control websites. The investigators hypothesize that at three, six, and 12 months post-baseline the intervention group will have increased safety seeking behaviors and reduced IPV exposure in comparison to the control group.
2. Test the effectiveness of an interactive internet-based safety decision aid on abused women's mental health compared to women assigned to control websites. The investigators hypothesize that at three, six, and 12 months post-baseline the intervention group will have improved mental health in comparison to the control group.
3. Test if the effect of an interactive internet-based safety decision aid on abused women's mental health and exposure to violence is mediated by the safety decision making process and safety-seeking behaviors. The investigators hypothesize that the intervention group will have a better decision making process and have greater safety seeking behavior over the year in comparison to the control group, and that this better decision process and increased safety seeking behavior will mediate improvement in mental health and exposure to violence at 12 months post baseline.

This study will provide much needed new information about safety planning's impact on making difficult safety decisions, exposure to violence, and mental health effects.


Options:
A: Severity of Violence Against Women (6 months); Women's Experience with Battering (6 months); Safety Behavior Checklist (6 months); Decisional Conflict Scale (6 months)
B: Reduction of risk behaviors:; Active smoking; Environmental Tobacco Smoke Exposure; Depression; Intimate Partner Violence
C: condom use (4.5 months)
D: Drug abstinence

Answer: A
Please select the outcome measures that correspond to the clinical trial below.
Title: Internet-Based Intervention to Improve Mental Health Outcomes for Abused Women
Brief Summary: The purpose for this trial is to test the effectiveness of the first interactive internet-based safety decision aid on abused women's exposure to repeat intimate partner violence (IPV) and mental health outcomes. An improved safety decision-making process (e.g., knowing the advantages and disadvantages of the relationship, having enough information to make a decision) will increase safety-seeking behaviors which in turn will decrease exposure to repeat IPV and improve mental health outcomes. Findings from the development and initial test of our computerized safety decision aid suggests that it offered abused women privacy to consider personalized safety options, informed them about danger in their relationship and would be used again if they had access to it through a safe internet site.

The investigators are conducting a five year experimental trial in four states (Oregon, Maryland, Missouri, and Arizona) to address the following aims:

1. Test the effectiveness of an interactive internet-based safety decision aid on abused women's safety seeking behaviors and exposure to violence compared to women assigned to control websites. The investigators hypothesize that at three, six, and 12 months post-baseline the intervention group will have increased safety seeking behaviors and reduced IPV exposure in comparison to the control group.
2. Test the effectiveness of an interactive internet-based safety decision aid on abused women's mental health compared to women assigned to control websites. The investigators hypothesize that at three, six, and 12 months post-baseline the intervention group will have improved mental health in comparison to the control group.
3. Test if the effect of an interactive internet-based safety decision aid on abused women's mental health and exposure to violence is mediated by the safety decision making process and safety-seeking behaviors. The investigators hypothesize that the intervention group will have a better decision making process and have greater safety seeking behavior over the year in comparison to the control group, and that this better decision process and increased safety seeking behavior will mediate improvement in mental health and exposure to violence at 12 months post baseline.

This study will provide much needed new information about safety planning's impact on making difficult safety decisions, exposure to violence, and mental health effects.


Options:
A: Mean Number of Skin Examinations Without Partner Over 4 Months (4 months); Mean Number of Skin Examinations With Partner Over 4 Months (4 months); Mean Number of Times Reviewed Skin Self Examination Guidelines Over 4 Months (4 months)
B: Severity of Violence Against Women (6 months); Women's Experience with Battering (6 months); Safety Behavior Checklist (6 months); Decisional Conflict Scale (6 months)
C: preferences (at time of interview)
D: Patient Adherence (Test Completion) (12 months post-intervention)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Effects of Two Hypocaloric Diets on Weight Loss and Inflammatory Markers
Brief Summary: The investigators evaluated whether an energy-restricted protein diet with low glycaemic index carbohydrates and soluble fibers (LC-P-LGI) would be more effective than a conventional diet (LC-CONV) on weight-loss and related metabolic variables.


Options:
A: weight change (Change from baseline to 24 months)
B: Change in insulin sensitivity between the two dietary arms (at 3-, 12- and 24 months); Change in BMI z-score between the two dietary groups (3-, 12-, and 24 months)
C: N/A
D: Insulin sensitivity (IVGTT and minimal model)

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: A 60-DAY, Open-label, Randomized Study to Evaluate the Efficacy and Safety of Eligen® B12 OR Intramuscularly Administered B12 in Subjects With Low Serum Cobalamin With a 30 Day Extension to 90 Days of Dosing
Brief Summary: The purpose of this study is to compare the efficacy and safety profile of a new oral vitamin B12 formulation (Eligen® B12) with intramuscular B12 in restoring normal B12 (cobalamin) concentrations in subjects with low cobalamin levels (\<350 pg/mL).


Options:
A: Serum vitamin B12 (1,2 and 3 months after administration of medicine)
B: Change from Cobalamin level standardization (1 year)
C: Serum Cobalamin Normalization (61 days)
D: To investigate the quality of the metabolic control of diabetes and related variables (daily dose of insulin, body weight).

Answer: C
Please select the outcome measures that correspond to the clinical trial below.
Title: Center for Achieving and Sustaining Improved Health in Harlem: Patient Education to Reduce Postpartum Depressive Symptoms Among Minority Women
Brief Summary: Postpartum depressive symptoms are a major health problem that affects hundreds of women annually. The investgators propose to test an intervention to reduce postpartum depressive symptoms and prevent elevated levels of depressive symptoms in postpartum mothers by preparing and educating women about specific situational triggers of depressive symptoms, by bolstering personal and social resources, by enhancing self-management skills to buffer postpartum demands, and by increasing access to existing healthcare and community resources available to postpartum mothers.


Options:
A: Number of Participants Breastfeeding Their Infants at 1 Month (1 month); Number of Participants Breastfeeding Their Infants at 3 Months (3 months); Number of Participants Breastfeeding Their Infants at 6 Months (6 months); Number of Participants Breastfeeding Their Infants at 9 Months (9 months); Number of Participants Breastfeeding Their Infants at 12 Months (12 months)
B: The primary outcome measure is to evaluate the effectiveness in a randomized controlled trial of a patient education intervention to reduce depressive symptoms among Black and Hispanic postpartum women. (Measured at baseline); The primary outcome measure is to evaluate the effectiveness in a randomized controlled trial of a patient education intervention to reduce depressive symptoms among Black and Hispanic postpartum women. (Measured at 3 weeks postpartum); The primary outcome measure is to evaluate the effectiveness in a randomized controlled trial of a patient education intervention to reduce depressive symptoms among Black and Hispanic postpartum women. (Measured at 3 months postpartum); The primary outcome measure is to evaluate the effectiveness in a randomized controlled trial of a patient education intervention to reduce depressive symptoms among Black and Hispanic postpartum women. (Measured at 6 months postpartum)
C: Percent of infants breastfed exclusively (4 weeks of age); Daily volume of formula supplement received by mixed feeders (at 4 weeks of age)
D: Mean weight-for-length z-score at 15 months of age (15 months of age)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Center for Achieving and Sustaining Improved Health in Harlem: Patient Education to Reduce Postpartum Depressive Symptoms Among Minority Women
Brief Summary: Postpartum depressive symptoms are a major health problem that affects hundreds of women annually. The investgators propose to test an intervention to reduce postpartum depressive symptoms and prevent elevated levels of depressive symptoms in postpartum mothers by preparing and educating women about specific situational triggers of depressive symptoms, by bolstering personal and social resources, by enhancing self-management skills to buffer postpartum demands, and by increasing access to existing healthcare and community resources available to postpartum mothers.


Options:
A: Number of significantly improved child and maternal outcomes (2 Years)
B: The primary outcome measure is to evaluate the effectiveness in a randomized controlled trial of a patient education intervention to reduce depressive symptoms among Black and Hispanic postpartum women. (Measured at baseline); The primary outcome measure is to evaluate the effectiveness in a randomized controlled trial of a patient education intervention to reduce depressive symptoms among Black and Hispanic postpartum women. (Measured at 3 weeks postpartum); The primary outcome measure is to evaluate the effectiveness in a randomized controlled trial of a patient education intervention to reduce depressive symptoms among Black and Hispanic postpartum women. (Measured at 3 months postpartum); The primary outcome measure is to evaluate the effectiveness in a randomized controlled trial of a patient education intervention to reduce depressive symptoms among Black and Hispanic postpartum women. (Measured at 6 months postpartum)
C: Mothers' scores on a postnatal depression scale (baseline, and when the child is 3, 6 and 12 months old) (baseline, and when the child is 3, 6 and 12 months old); Parental competencies (when the child is 3, 12 and 18 months old) (when the child is 3, 12 and 18 months old); Child mental health (when the child is 18 and 24 months old) (when the child is 18 and 24 months old)
D: Maternal life-course (reflected in reduced total public benefit expenditures for SNAP, AFDC/TANF, and Medicaid). (through first child age 18); Cognitive, language, and academic functioning among first-born children. (at youth age 18); Youth depression and anxiety (at youth age 18); Youth gang membership, arrests, convictions, and self-reported antisocial behavior, especially for crimes involving interpersonal violence. (at youth age 18); Youth risk for HIV infection, pregnancies, births, use of substances, and SUDs. (at youth age 18.)

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Center for Achieving and Sustaining Improved Health in Harlem: Patient Education to Reduce Postpartum Depressive Symptoms Among Minority Women
Brief Summary: Postpartum depressive symptoms are a major health problem that affects hundreds of women annually. The investgators propose to test an intervention to reduce postpartum depressive symptoms and prevent elevated levels of depressive symptoms in postpartum mothers by preparing and educating women about specific situational triggers of depressive symptoms, by bolstering personal and social resources, by enhancing self-management skills to buffer postpartum demands, and by increasing access to existing healthcare and community resources available to postpartum mothers.


Options:
A: Percent of infants breastfed exclusively (4 weeks of age); Daily volume of formula supplement received by mixed feeders (at 4 weeks of age)
B: The primary outcome measure is to evaluate the effectiveness in a randomized controlled trial of a patient education intervention to reduce depressive symptoms among Black and Hispanic postpartum women. (Measured at baseline); The primary outcome measure is to evaluate the effectiveness in a randomized controlled trial of a patient education intervention to reduce depressive symptoms among Black and Hispanic postpartum women. (Measured at 3 weeks postpartum); The primary outcome measure is to evaluate the effectiveness in a randomized controlled trial of a patient education intervention to reduce depressive symptoms among Black and Hispanic postpartum women. (Measured at 3 months postpartum); The primary outcome measure is to evaluate the effectiveness in a randomized controlled trial of a patient education intervention to reduce depressive symptoms among Black and Hispanic postpartum women. (Measured at 6 months postpartum)
C: Use of unplanned maternal and child healthcare services (inpatient, Emergency Department (ED), urgent/acute care, primary care, and mental health) in the first 14 days after delivery (3 years)
D: Neonatal mortality rate

Answer: B
Please select the outcome measures that correspond to the clinical trial below.
Title: Randomized, Double-blind, Placebo-controlled, Parallel Group Study to Assess the Efficacy, Safety, and Tolerability of SAR231893/REGN668 Administered Subcutaneously Once Weekly for 12 Weeks in Patients With Persistent Moderate to Severe Eosinophilic Asthma Who Are Partially Controlled/Uncontrolled by Inhaled Corticosteroid Plus Long-acting beta2 Agonist Therapy
Brief Summary: Primary Objective:

To investigate the effects of Dupilumab (SAR231893/REGN668) administered subcutaneously (SC) once weekly (qw) for 12 weeks as compared to placebo on reducing the incidence of asthma exacerbation in participants with persistent moderate to severe eosinophilic asthma.

Secondary Objectives:

* To assess the safety and tolerability of Dupilumab administered SC qw for 12 weeks in participants with persistent moderate to severe eosinophilic asthma.
* To assess Dupilumab serum concentrations following qw SC dosing for 12 weeks in participants with persistent moderate to severe eosinophilic asthma.


Options:
A: Percentage of Participants With Asthma Exacerbation (Baseline up to Week 12)
B: Number of severe asthma patients eligible for one or more biologic treatments for asthma (Day 1)
C: Change From Baseline in the Expression of FcεRI Receptors of Blood Basophils (Baseline and 16 weeks); Change From Baseline in the Expression of FcεRI Receptors of Dendritic Cells (Baseline and 16 weeks)
D: Percentage of Participants With First Clinically Significant Exacerbation in Part C (Weeks 12, 24, 36 and 52)

Answer: A