Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Tailored Tobacco Intervention
Brief Summary: The project is designed to examine the effectiveness of strategies to increase access to treatment for tobacco use and dependence among rural Veteran smokers. In addition, it will examine whether tailored treatment that is designed to address common comorbid conditions that are related to cigarette smoking enhances success with quitting relative to enhanced standard of care. The investigators hypothesize that participants assigned to the tailored tobacco cessation intervention will report greater cessation rates at six months. The investigators also anticipate more favorable outcomes on measures of depressive symptoms, alcohol use, and body weight.


Options:
A: Arm Label: Varenicline; Type: EXPERIMENTAL; Interventions: Drug: Varenicline(Chantix) | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Varenicline(Chantix); Assigned to Arm(s): Varenicline | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
B: Arm Label: Varenicline; Type: ACTIVE_COMPARATOR; Interventions: Drug: Varenicline | Arm Label: Sugar Pil; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Intervention Type: DRUG; Name: Varenicline; Assigned to Arm(s): Varenicline | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): Sugar Pil
C: Arm Label: Tailored intervention; Type: EXPERIMENTAL; Interventions: Drug: Nicotine replacement therapy - Transdermal nicotine patch, Drug: Nicotine replacement therapy - Nicotine gum, Drug: Nicotine replacement therapy - Nicotine lozenge, Drug: Bupropion, Drug: Varenicline, Drug: Combination pharmacotherapy - Transdermal nicotine patch + nicotine gum, Drug: Combination pharmacotherapy - Transdermal nicotine patch + nicotine lozenge, Drug: Combination pharmacotherapy - Transdermal nicotine patch + bupropion, Behavioral: Tailored behavioral intervention, Behavioral: Alcohol use risk reduction, Behavioral: Behavioral activation for depressive symptoms, Behavioral: Behavioral management of postcessation weight gain | Arm Label: Enhanced standard of care; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine replacement therapy - Transdermal nicotine patch, Drug: Nicotine replacement therapy - Nicotine gum, Drug: Nicotine replacement therapy - Nicotine lozenge, Drug: Bupropion, Drug: Varenicline, Drug: Combination pharmacotherapy - Transdermal nicotine patch + nicotine gum, Drug: Combination pharmacotherapy - Transdermal nicotine patch + nicotine lozenge, Drug: Combination pharmacotherapy - Transdermal nicotine patch + bupropion, Behavioral: Tobacco quitline referral | Intervention Type: DRUG; Name: Nicotine replacement therapy - Transdermal nicotine patch; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: DRUG; Name: Nicotine replacement therapy - Nicotine gum; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: DRUG; Name: Nicotine replacement therapy - Nicotine lozenge; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: DRUG; Name: Bupropion; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: DRUG; Name: Varenicline; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: DRUG; Name: Combination pharmacotherapy - Transdermal nicotine patch + nicotine gum; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: DRUG; Name: Combination pharmacotherapy - Transdermal nicotine patch + nicotine lozenge; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: DRUG; Name: Combination pharmacotherapy - Transdermal nicotine patch + bupropion; Assigned to Arm(s): Enhanced standard of care, Tailored intervention | Intervention Type: BEHAVIORAL; Name: Tobacco quitline referral; Assigned to Arm(s): Enhanced standard of care | Intervention Type: BEHAVIORAL; Name: Tailored behavioral intervention; Assigned to Arm(s): Tailored intervention | Intervention Type: BEHAVIORAL; Name: Alcohol use risk reduction; Assigned to Arm(s): Tailored intervention | Intervention Type: BEHAVIORAL; Name: Behavioral activation for depressive symptoms; Assigned to Arm(s): Tailored intervention | Intervention Type: BEHAVIORAL; Name: Behavioral management of postcessation weight gain; Assigned to Arm(s): Tailored intervention
D: Arm Label: NRT arm; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine Replacement Therapy (NRT) | Arm Label: NRT and HIV Tailored Quit Smoking Counseling; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nicotine Replacement Therapy (NRT), Behavioral: HIV Tailored Quit Smoking Counseling | Arm Label: Varenicline (VR) Arm; Type: ACTIVE_COMPARATOR; Interventions: Drug: Varenicline | Arm Label: Varenicline (VR) and HIV Tailored Quit Smoking Counseling; Type: ACTIVE_COMPARATOR; Interventions: Drug: Varenicline, Behavioral: HIV Tailored Quit Smoking Counseling | Intervention Type: DRUG; Name: Nicotine Replacement Therapy (NRT); Assigned to Arm(s): NRT and HIV Tailored Quit Smoking Counseling, NRT arm | Intervention Type: DRUG; Name: Varenicline; Assigned to Arm(s): Varenicline (VR) Arm, Varenicline (VR) and HIV Tailored Quit Smoking Counseling | Intervention Type: BEHAVIORAL; Name: HIV Tailored Quit Smoking Counseling; Assigned to Arm(s): NRT and HIV Tailored Quit Smoking Counseling, Varenicline (VR) and HIV Tailored Quit Smoking Counseling

Answer: C