Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Effect and Mechanism of wCST-LL Based Precision Rehabilitation Nursing on Motor Dysfunction After Acute Stroke
Brief Summary: Ischemic stroke is the main cause of disability in the world. More than 70% of stroke patients show various degrees of neural function impairment. Motor rehabilitation in acute phase is beneficial for improving patient's structure and function of corticospinal tract. However, it is difficult to obtain effective rehabilitation during the acute phase of stroke because of the insufficiency of professional rehabilitation therapists in stroke wards in China.The present study is to verify that nursing-directed rehabilitation can compensate for the shortage of professional rehabilitation therapists. Our previous study indicated that nursing-directed motor function rehabilitation provided more obvious effect on stroke patients with a weighted corticospinal tract lesion load (wCST-LL) smaller than 2ml. We assume that implementing rehabilitation nursing based on the wCST-LL can realize nursing-directed, wCST-LL-based precision motor rehabilitation during acute phase of ischemic stroke.The present study is to conduct randomized clinical trial to confirm the effect of nursing-directed precision rehabilitation for motor function in acute stroke patients grouped by wCST-LL, and to evaluate the effect of this precision rehabilitation by using functional scale, and to explore the histopathologic mechanism of the precision rehabilitation nursing by mean of neuroelectrophysiology and neuroimaging examination. This study might provide theoretical support for motor rehabilitation in patients during acute phase of stroke.


Options:
A: Arm Label: Active tDCS + robotic therapy + physical therapy; Type: ACTIVE_COMPARATOR; Interventions: Device: Robotic Therapy, Device: Active tDCS, Other: Physical Therapy | Arm Label: sham tDCS + robotic therapy + physical therapy; Type: ACTIVE_COMPARATOR; Interventions: Device: Robotic Therapy, Device: Sham tDCS, Other: Physical Therapy | Arm Label: sham tDCS + physical therapy + occupational therapy; Type: EXPERIMENTAL; Interventions: Device: Sham tDCS, Other: Physical Therapy, Other: Occupational Therapy | Intervention Type: DEVICE; Name: Robotic Therapy; Assigned to Arm(s): Active tDCS + robotic therapy + physical therapy, sham tDCS + robotic therapy + physical therapy | Intervention Type: DEVICE; Name: Active tDCS; Assigned to Arm(s): Active tDCS + robotic therapy + physical therapy | Intervention Type: DEVICE; Name: Sham tDCS; Assigned to Arm(s): sham tDCS + physical therapy + occupational therapy, sham tDCS + robotic therapy + physical therapy | Intervention Type: OTHER; Name: Physical Therapy; Assigned to Arm(s): Active tDCS + robotic therapy + physical therapy, sham tDCS + physical therapy + occupational therapy, sham tDCS + robotic therapy + physical therapy | Intervention Type: OTHER; Name: Occupational Therapy; Assigned to Arm(s): sham tDCS + physical therapy + occupational therapy
B: Arm Label: Usual care; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Usual Care | Arm Label: FAST protocol; Type: EXPERIMENTAL; Interventions: Behavioral: FAST protocol | Intervention Type: BEHAVIORAL; Name: Usual Care; Assigned to Arm(s): Usual care | Intervention Type: BEHAVIORAL; Name: FAST protocol; Assigned to Arm(s): FAST protocol
C: Arm Label: Active low-frequency rTMS/sham tDCS; Type: EXPERIMENTAL; Interventions: Device: Repetitive Transcranial Magnetic Stimulation (rTMS), Device: Transcranial Direct Current Stimulation (tDCS) | Arm Label: Active high-frequency rTMS/sham tDCS; Type: EXPERIMENTAL; Interventions: Device: Repetitive Transcranial Magnetic Stimulation (rTMS), Device: Transcranial Direct Current Stimulation (tDCS) | Arm Label: Sham rTMS/active anodal tDCS; Type: EXPERIMENTAL; Interventions: Device: Repetitive Transcranial Magnetic Stimulation (rTMS), Device: Transcranial Direct Current Stimulation (tDCS) | Arm Label: Sham rTMS/active cathodal tDCS; Type: EXPERIMENTAL; Interventions: Device: Repetitive Transcranial Magnetic Stimulation (rTMS), Device: Transcranial Direct Current Stimulation (tDCS) | Arm Label: Sham rTMS/Sham tDCS; Type: SHAM_COMPARATOR; Interventions: Device: Repetitive Transcranial Magnetic Stimulation (rTMS), Device: Transcranial Direct Current Stimulation (tDCS) | Intervention Type: DEVICE; Name: Repetitive Transcranial Magnetic Stimulation (rTMS); Assigned to Arm(s): Active high-frequency rTMS/sham tDCS, Active low-frequency rTMS/sham tDCS, Sham rTMS/Sham tDCS, Sham rTMS/active anodal tDCS, Sham rTMS/active cathodal tDCS | Intervention Type: DEVICE; Name: Transcranial Direct Current Stimulation (tDCS); Assigned to Arm(s): Active high-frequency rTMS/sham tDCS, Active low-frequency rTMS/sham tDCS, Sham rTMS/Sham tDCS, Sham rTMS/active anodal tDCS, Sham rTMS/active cathodal tDCS
D: Arm Label: Experimental group; Type: EXPERIMENTAL; Interventions: Other: functional rehabilitation nursing program | Arm Label: control group; Type: EXPERIMENTAL; Interventions: Other: control group | Intervention Type: OTHER; Name: functional rehabilitation nursing program; Assigned to Arm(s): Experimental group | Intervention Type: OTHER; Name: control group; Assigned to Arm(s): control group

Answer: D