Please select the eligibility criteria that correspond to the clinical trial below.
Title: ResQ Trial: Comparison of Standard CPR Alone Versus Active Compression Decompression CPR Plus an ITD on Survival From Out-of-Hospital Cardiac Arrest
Brief Summary: The purpose of this study is to determine whether performing active compression decompression cardiopulmonary resuscitation (ACD-CPR) with an impedance threshold device (ITD) compared to conventional standard cardiopulmonary resuscitation (S-CPR) will impact the neurologic recovery and survival to hospital discharge following out-of-hospital cardiac arrest.


Options:
A: Inclusion Criteria:

* Patents aged 18 years (or local age of consent) or more who suffer non-traumatic arrest of presumed cardiac etiology in an out-of-hospital setting and who do not meet any of the exclusion criteria below.

Exclusion Criteria:

* Traumatic arrest (blunt, penetrating, burns)
* Arrest due to exsanguinations, strangulation, smoke inhalation, drug overdose, electrocution, hanging, drowning.
* Known or clinically apparent pregnancy
* Do Not Attempt to Resuscitate (DNAR) orders
* Apparent patient weight more than 225 kg (500 lbs)
* Wards of the state
* Prisoner
* CPR device other than AutoPulse
* Patients who are reached after 16 minutes after the time of emergency call (911). This exclusion is determined at the time of CRF abstraction, not during treatment of the patient.

  * If patient is unaccompanied, or accompanied by a person or persons unfamiliar with their his-tory, determination of these exclusion criteria will, perforce, be left to the best estimation of the rescue personnel. At no time, should an attempt to determine these criteria be allowed to delay the administration of life-saving treatment.

    * These criteria will be determined in the best estimation of the rescue personnel, or if the AutoPulse signals that the patient is outside the parameters for AutoPulse deployment.
B: Inclusion Criteria:

* Adult subjects initially presumed or known to be 18 years of age or older
* Subjects who present with out-of-hospital cardiac arrest from presumed cardiac etiology and who receive CPR by Emergency Medical Services (EMS) personnel for at least 1 minute
* Subjects whose airways are managed with a cuffed ET tube, combitube, or laryngeal mask airway or facemask

Exclusion Criteria:

* Adult subjects presumed or known to be less than 18 years of age
* Subjects with known or likely traumatic injuries causing cardiac arrest or cardiac arrest of presumed noncardiac origin
* Subjects with preexisting Do Not Resuscitate (DNR) orders
* Subjects with signs of obvious clinical death or conditions that preclude the use of CPR
* Family or legal representative request that the subject not be entered into the study
* Subjects experiencing in-hospital cardiac arrest
* Subjects with a recent sternotomy with wound not appearing completely healed (if unknown) or less than 6 months (if known)
* Subjects who received less than 1 minute of CPR by EMS personnel
* Subjects with a complete airway obstruction that cannot be cleared or in whom attempts at advanced airway management are unsuccessful
* Subjects intubated with a leaky or uncuffed advanced airway device or presence of stomas, tracheotomies, or tracheostomies
* Subjects who rearrest and are encountered by EMS within 365 days of the index cardiac arrest
C: Inclusion Criteria:

* All persons with out-of-hospital cardiac arrest who are attended by a vehicle involved in the randomization process and who are treated by the emergency medical service (EMS).

Exclusion Criteria:

* Persons under the age of 18
* Victims with traumatic arrest
* Less than the legal age of consent
* Resuscitation attempt discontinued because of do not resuscitate (DNR) orders or on request of authorized decision-maker
* Wards of the state, including prisoners
* Chest or abdominal surgery within 6 weeks
* Site specific exclusions
D: Inclusion Criteria:

* All persons of local age of consent or older who suffer non-traumatic cardiopulmonary arrest outside of the hospital in the study communities with defibrillation and/or delivery of chest compressions provided by emergency medical service (EMS) providers dispatched to the scene and do not meet any of the exclusion criteria.

Exclusion Criteria:

Common:

* Do not attempt resuscitation (DNAR) orders
* Blunt, penetrating, or burn-related injury
* Patients with exsanguinations
* Known prisoners
* Known pregnancy
* Non-ROC EMS agency/provider

For Analyzing Late versus Early

* EMS-witnessed arrests
* Non-EMS rhythm analysis (AED placed by police or lay responder is an exclusion but CPR by lay or other non-EMS responders is not)

For ITD:

* Tracheostomy present
* CPR performed with the mechanical compression "Autopulse" device.

Answer: B