Please select the eligibility criteria that correspond to the clinical trial below.
Title: Association of Intravenous Ketamine With Thoracic Epidural Analgesia: Effects on Pain and Respiratory Function Following Thoracotomy.
Brief Summary: Thoracotomy for lung resection is deemed painful. Ketamine is now a renewed interest in preventing acute postoperative pain. A previous study performed in the service testing the association ketamine/morphine versus morphine PCA, postoperative, for patients who do not benefit from postoperative epidural thoracic surgery, has demonstrated a reduction of postoperative pain associated with a reduction of nocturnal arterial desaturation following surgery when ketamine was added to morphine.


Options:
A: Inclusion Criteria:

* Adult ASA I - II patients, scheduled for unilateral mastectomy or tumorectomy associated with axillary lymph node dissection

Exclusion Criteria:

* Patients receiving opioid or any other analgesic treatment for chronic pain before surgery, patients with known allergy to local anaesthetics, and patients with acquired or genetic haemostatic abnormality
B: Inclusion Criteria:

* Male and females 18-85 years old scheduled to use PCA with morphine for postoperative pain control
* HIV-negative
* Classification American Society of Anesthesiologists (ASA) I: without systemic disease
* Classification ASA II or III (moderate systemic disease or severe systemic disease that limits activity without disability)
* Scheduled for major abdominal and urologic surgery (no emergency surgery)

Exclusion Criteria:

* regular use of opioid analgesics;
* History of abuse of drugs and / or alcohol;
* Postoperative hospitalization in intensive care with sedation and / or mechanical ventilation;
* severe renal impairment (creatinine\> 2 g / dl, creatinine clearance \<30 ml / h) and / or hepatic impairment (cholinesterase \<2000 IU);
* Cardiac disorders (arrhythmias, heart failure);
* Neurological disorders (epilepsy);
* Cognitive disorders, mental retardation, psychiatric disorders;
* Changes in the normal coagulation or coagulopathy (INR\> 2, PTT\> 44 sec);
* Platelet count less than 100.000/mm3;
* BMI\> 30;
* Allergy to study drugs.
* diabetes type I/II
C: Inclusion Criteria:

* Subject between 18 and 85 years
* subject of both sexes
* subject operated in the service of thoracic surgery of a lobectomy by thoracotomie lateral or postlaterale subject
* subject operated in settled surgery

Exclusion Criteria:

* Against indication in the epidural insanity,
* confusionnel, patient psychotic
* treatment in the long price by medicine which can interfere on the pain (morphine, antidepressants, psychotropic treatment)
D: Inclusion Criteria:

* Age \>18, Visual Analog. Scale (VAS) pain score \>70mm which was frequent or continuous one week before scheduled major (above or below knee) amputation, and patient consent.

Exclusion Criteria:

* No written patient consent
* Age \< 18 years
* Age \> 82 years
* Antiplatelet medication
* Mental status not acceptable
* Exclusion criteria were age \>85
* Emergency amputation
* Ipsilateral re-amputation
* Foot or toe amputation
* Inability to complete a detailed pain questionnaire
* History of chronic pain or substance abuse
* Active psychiatric disease requiring treatment
* Any contraindication to epidural catheter placement (anticoagulation, anti-platelet medications, previous lumbar spine surgery).

Answer: C