TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Role of Inflammatory and Stress Response in the Pathogenesis of Cognitive Dysfunction After Cardiac Surgery
Brief Summary: Postoperative cognitive dysfunction (POCD) is the most common complication after cardiac surgery. This prospective study was conducted to investigate the mechanisms of development of POCD following cardiac surgery taking into account surgical technique (with use or no use of extracorporeal circulation). The investigators focused on the role of inflammatory and stress response to surgical procedure as potential factors involved in the pathogenesis of cognitive dysfunction. Systematic inflammatory response in patients undergoing on-pump or off-pump surgery was analyzed by measuring serum levels of C reactive protein (CRP) and occurrence of systemic inflammatory response syndrome (SIRS). Stress response to surgery was evaluated following cortisol levels and its daily variations. The degree of cognitive dysfunction was assessed based on serum levels of S100β. The effect of dexamethasone on the levels of stress and inflammatory response biomarkers, serum levels of S100β, as well as on the development of POCD was compared with control group that received normal saline.


Options:
A: Arm Label: Xenon; Type: EXPERIMENTAL; Interventions: Drug: Xenon | Arm Label: Sevoflurane; Type: ACTIVE_COMPARATOR; Interventions: Drug: Sevoflurane | Intervention Type: DRUG; Name: Xenon; Assigned to Arm(s): Xenon | Intervention Type: DRUG; Name: Sevoflurane; Assigned to Arm(s): Sevoflurane
B: Arm Label: Study (CytoSorb); Type: EXPERIMENTAL; Interventions: Device: CytoSorb | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Corticosteroid; Type: ACTIVE_COMPARATOR; Interventions: Drug: Methylprednisolone | Intervention Type: DEVICE; Name: CytoSorb; Assigned to Arm(s): Study (CytoSorb) | Intervention Type: DRUG; Name: Methylprednisolone; Assigned to Arm(s): Corticosteroid
C: Arm Label: Dexamethasone; Type: EXPERIMENTAL; Interventions: Drug: Dexamethasone | Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Intervention Type: DRUG; Name: Dexamethasone; Assigned to Arm(s): Dexamethasone | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Control
D: Arm Label: 1; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: 2; Type: EXPERIMENTAL; Interventions: Drug: epoetinum | Intervention Type: DRUG; Name: epoetinum; Assigned to Arm(s): 2

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: The Role of Inflammatory and Stress Response in the Pathogenesis of Cognitive Dysfunction After Cardiac Surgery
Brief Summary: Postoperative cognitive dysfunction (POCD) is the most common complication after cardiac surgery. This prospective study was conducted to investigate the mechanisms of development of POCD following cardiac surgery taking into account surgical technique (with use or no use of extracorporeal circulation). The investigators focused on the role of inflammatory and stress response to surgical procedure as potential factors involved in the pathogenesis of cognitive dysfunction. Systematic inflammatory response in patients undergoing on-pump or off-pump surgery was analyzed by measuring serum levels of C reactive protein (CRP) and occurrence of systemic inflammatory response syndrome (SIRS). Stress response to surgery was evaluated following cortisol levels and its daily variations. The degree of cognitive dysfunction was assessed based on serum levels of S100β. The effect of dexamethasone on the levels of stress and inflammatory response biomarkers, serum levels of S100β, as well as on the development of POCD was compared with control group that received normal saline.


Options:
A: Arm Label: Treatment; Type: EXPERIMENTAL; Interventions: Drug: Methylprednisolone | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Intervention Type: DRUG; Name: Methylprednisolone; Assigned to Arm(s): Treatment | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Placebo
B: Arm Label: Single dose steroid; Type: EXPERIMENTAL; Interventions: Drug: methylprednisolone (IVMP) | Arm Label: Two Dose steroid; Type: EXPERIMENTAL; Interventions: Drug: methylprednisolone (two doses IVMP) | Intervention Type: DRUG; Name: methylprednisolone (IVMP); Assigned to Arm(s): Single dose steroid | Intervention Type: DRUG; Name: methylprednisolone (two doses IVMP); Assigned to Arm(s): Two Dose steroid
C: Arm Label: A; Type: PLACEBO_COMPARATOR; Interventions: Drug: Hydrocortisone | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Drug: Hydrocortisone | Intervention Type: DRUG; Name: Hydrocortisone; Assigned to Arm(s): A, B
D: Arm Label: Dexamethasone; Type: EXPERIMENTAL; Interventions: Drug: Dexamethasone | Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Intervention Type: DRUG; Name: Dexamethasone; Assigned to Arm(s): Dexamethasone | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Control

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized Community Trial of Physical Activity Intervention in Primary Healthcare to Improve Cardiovascular Risk Factors and Health-Related Quality of Life in Older Adults
Brief Summary: Community intervention trial, randomized, to promote regular PA and social and cultural support activities for 9 months in older-adult primary care users and assess their effects on cardiovascular risk factors and health-related quality of life.


Options:
A: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Physical training | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: No training | Intervention Type: BEHAVIORAL; Name: Physical training; Assigned to Arm(s): 1 | Intervention Type: BEHAVIORAL; Name: No training; Assigned to Arm(s): 2
B: Arm Label: Intensive exercise; Type: EXPERIMENTAL; Interventions: Other: Intensive exercise | Arm Label: Lifestyle counseling; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Regular exercise; Type: EXPERIMENTAL; Interventions: Other: Conventional exercise | Intervention Type: OTHER; Name: Intensive exercise; Assigned to Arm(s): Intensive exercise | Intervention Type: OTHER; Name: Conventional exercise; Assigned to Arm(s): Regular exercise
C: Arm Label: Physical, social and cultural activities; Type: EXPERIMENTAL; Interventions: Behavioral: Physical, social and cultural activities | Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Physical, social and cultural activities; Assigned to Arm(s): Physical, social and cultural activities
D: Arm Label: Basic Pedometry Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Basic Intervention | Arm Label: Enhanced Pedometry Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Enhanced Pedometry | Arm Label: Control Group; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Control Group | Intervention Type: BEHAVIORAL; Name: Basic Intervention; Assigned to Arm(s): Basic Pedometry Intervention | Intervention Type: BEHAVIORAL; Name: Enhanced Pedometry; Assigned to Arm(s): Enhanced Pedometry Intervention | Intervention Type: BEHAVIORAL; Name: Control Group; Assigned to Arm(s): Control Group

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Physiology and Therapeutic Management of Neonatal Abstinence Syndrome
Brief Summary: The overall purpose of this project is to to quantify the physiology of neonatal drug withdrawal and develop non-pharmacological techniques to help improve the therapeutic management of Neonatal Abstinence Syndrome (NAS).


Options:
A: Arm Label: SVS vs Control; Type: EXPERIMENTAL; Interventions: Device: Stochastic Vibrotactile Stimulation (SVS), Other: Control | Intervention Type: DEVICE; Name: Stochastic Vibrotactile Stimulation (SVS); Assigned to Arm(s): SVS vs Control | Intervention Type: OTHER; Name: Control; Assigned to Arm(s): SVS vs Control
B: Arm Label: Song of Kin; Type: EXPERIMENTAL; Interventions: Behavioral: Song of Kin | Arm Label: Gato box; Type: EXPERIMENTAL; Interventions: Other: Gato box | Arm Label: Ocean disc; Type: EXPERIMENTAL; Interventions: Other: Ocean disc | Arm Label: Contingent singing; Type: EXPERIMENTAL; Interventions: Other: Contingent singing | Arm Label: Tonal Vocal holding; Type: EXPERIMENTAL; Interventions: Other: Tonal Vocal holding | Arm Label: Muted shaker; Type: EXPERIMENTAL; Interventions: Other: Muted shaker | Intervention Type: BEHAVIORAL; Name: Song of Kin; Assigned to Arm(s): Song of Kin | Intervention Type: OTHER; Name: Gato box; Assigned to Arm(s): Gato box | Intervention Type: OTHER; Name: Ocean disc; Assigned to Arm(s): Ocean disc | Intervention Type: OTHER; Name: Contingent singing; Assigned to Arm(s): Contingent singing | Intervention Type: OTHER; Name: Tonal Vocal holding; Assigned to Arm(s): Tonal Vocal holding | Intervention Type: OTHER; Name: Muted shaker; Assigned to Arm(s): Muted shaker
C: Arm Label: Clonidine treatment; Type: EXPERIMENTAL; Interventions: Drug: Clonidine HCL | Intervention Type: DRUG; Name: Clonidine HCL; Assigned to Arm(s): Clonidine treatment
D: Arm Label: Buprenorphine; Type: EXPERIMENTAL; Interventions: Drug: Buprenorphine | Arm Label: Methadone; Type: ACTIVE_COMPARATOR; Interventions: Drug: Methadone | Intervention Type: DRUG; Name: Methadone; Assigned to Arm(s): Methadone | Intervention Type: DRUG; Name: Buprenorphine; Assigned to Arm(s): Buprenorphine

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Physiology and Therapeutic Management of Neonatal Abstinence Syndrome
Brief Summary: The overall purpose of this project is to to quantify the physiology of neonatal drug withdrawal and develop non-pharmacological techniques to help improve the therapeutic management of Neonatal Abstinence Syndrome (NAS).


Options:
A: Arm Label: Song of Kin; Type: EXPERIMENTAL; Interventions: Behavioral: Song of Kin | Arm Label: Gato box; Type: EXPERIMENTAL; Interventions: Other: Gato box | Arm Label: Ocean disc; Type: EXPERIMENTAL; Interventions: Other: Ocean disc | Arm Label: Contingent singing; Type: EXPERIMENTAL; Interventions: Other: Contingent singing | Arm Label: Tonal Vocal holding; Type: EXPERIMENTAL; Interventions: Other: Tonal Vocal holding | Arm Label: Muted shaker; Type: EXPERIMENTAL; Interventions: Other: Muted shaker | Intervention Type: BEHAVIORAL; Name: Song of Kin; Assigned to Arm(s): Song of Kin | Intervention Type: OTHER; Name: Gato box; Assigned to Arm(s): Gato box | Intervention Type: OTHER; Name: Ocean disc; Assigned to Arm(s): Ocean disc | Intervention Type: OTHER; Name: Contingent singing; Assigned to Arm(s): Contingent singing | Intervention Type: OTHER; Name: Tonal Vocal holding; Assigned to Arm(s): Tonal Vocal holding | Intervention Type: OTHER; Name: Muted shaker; Assigned to Arm(s): Muted shaker
B: Arm Label: sublingual buprenorphine; Type: EXPERIMENTAL; Interventions: Drug: sublingual buprenorphine | Arm Label: oral morphine; Type: ACTIVE_COMPARATOR; Interventions: Drug: oral morphine | Intervention Type: DRUG; Name: sublingual buprenorphine; Assigned to Arm(s): sublingual buprenorphine | Intervention Type: DRUG; Name: oral morphine; Assigned to Arm(s): oral morphine
C: Arm Label: Low lactose formula; Type: ACTIVE_COMPARATOR; Interventions: Other: Low lactose or regular formula | Arm Label: Regular formula; Type: ACTIVE_COMPARATOR; Interventions: Other: Low lactose or regular formula | Intervention Type: OTHER; Name: Low lactose or regular formula; Assigned to Arm(s): Low lactose formula, Regular formula
D: Arm Label: SVS vs Control; Type: EXPERIMENTAL; Interventions: Device: Stochastic Vibrotactile Stimulation (SVS), Other: Control | Intervention Type: DEVICE; Name: Stochastic Vibrotactile Stimulation (SVS); Assigned to Arm(s): SVS vs Control | Intervention Type: OTHER; Name: Control; Assigned to Arm(s): SVS vs Control

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Physiology and Therapeutic Management of Neonatal Abstinence Syndrome
Brief Summary: The overall purpose of this project is to to quantify the physiology of neonatal drug withdrawal and develop non-pharmacological techniques to help improve the therapeutic management of Neonatal Abstinence Syndrome (NAS).


Options:
A: Arm Label: Standard therapy plus Aromatherapy; Type: EXPERIMENTAL; Interventions: Drug: lavender and chamomile essential oils | Arm Label: Standard therapy ALONE; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DRUG; Name: lavender and chamomile essential oils; Assigned to Arm(s): Standard therapy plus Aromatherapy
B: Arm Label: Oral glucose solution + maternal holding; Type: EXPERIMENTAL; Interventions: Other: Oral glucose solution + maternal holding | Arm Label: Breastfeeding; Type: EXPERIMENTAL; Interventions: Other: Breastfeeding | Arm Label: Oral glucose solution; Type: ACTIVE_COMPARATOR; Interventions: Other: Oral glucose solution | Arm Label: Oral expressed breastmilk; Type: ACTIVE_COMPARATOR; Interventions: Other: Oral expressed breastmilk | Intervention Type: OTHER; Name: Oral glucose solution + maternal holding; Assigned to Arm(s): Oral glucose solution + maternal holding | Intervention Type: OTHER; Name: Breastfeeding; Assigned to Arm(s): Breastfeeding | Intervention Type: OTHER; Name: Oral glucose solution; Assigned to Arm(s): Oral glucose solution | Intervention Type: OTHER; Name: Oral expressed breastmilk; Assigned to Arm(s): Oral expressed breastmilk
C: Arm Label: Stochastic Vibrotactile Stimulation (SVS); Type: EXPERIMENTAL; Interventions: Device: Stochastic Vibrotactile Stimulation (SVS) | Arm Label: Treatment as Usual (TAU); Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: DEVICE; Name: Stochastic Vibrotactile Stimulation (SVS); Assigned to Arm(s): Stochastic Vibrotactile Stimulation (SVS)
D: Arm Label: SVS vs Control; Type: EXPERIMENTAL; Interventions: Device: Stochastic Vibrotactile Stimulation (SVS), Other: Control | Intervention Type: DEVICE; Name: Stochastic Vibrotactile Stimulation (SVS); Assigned to Arm(s): SVS vs Control | Intervention Type: OTHER; Name: Control; Assigned to Arm(s): SVS vs Control

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Aphasia Telerehabilitation Post Stroke
Brief Summary: This study aims at contributing with scientific evidence to the field of aphasia telerehabilitation. In Norway today, there is an unmet need for language training in post stroke aphasia and not all patients are offered language training. Early start of aphasia rehabilitation and satisfying intensity do not seem to be standard clinical practice. Language training by telemedicine could improve this situation, and this study seeks to answer the question whether aphasia rehabilitation delivered by videoconference can improve language function in aphasia post stroke.


Options:
A: Arm Label: Case management; Type: EXPERIMENTAL; Interventions: Behavioral: Case management | Arm Label: usual care; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Case management | Intervention Type: BEHAVIORAL; Name: Case management; Assigned to Arm(s): Case management | Intervention Type: BEHAVIORAL; Name: Case management; Assigned to Arm(s): usual care
B: Arm Label: In-person behavioral intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Brief pleasurable events/behavioral therapy | Arm Label: Telephone behavioral intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Brief pleasurable events/behavioral therapy | Arm Label: Standard care; Type: ACTIVE_COMPARATOR; Interventions: Other: Standard care | Intervention Type: BEHAVIORAL; Name: Brief pleasurable events/behavioral therapy; Assigned to Arm(s): In-person behavioral intervention, Telephone behavioral intervention | Intervention Type: OTHER; Name: Standard care; Assigned to Arm(s): Standard care
C: Arm Label: Aphasia telerehabilitation; Type: EXPERIMENTAL; Interventions: Other: Aphasia telerehabilitation, Other: Standard face-to-face aphasia rehabilitation | Arm Label: Control; Type: ACTIVE_COMPARATOR; Interventions: Other: Standard face-to-face aphasia rehabilitation | Intervention Type: OTHER; Name: Aphasia telerehabilitation; Assigned to Arm(s): Aphasia telerehabilitation | Intervention Type: OTHER; Name: Standard face-to-face aphasia rehabilitation; Assigned to Arm(s): Aphasia telerehabilitation, Control
D: Arm Label: Usual Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: SCM; Type: EXPERIMENTAL; Interventions: Other: SCM | Arm Label: SCM and VSSP; Type: EXPERIMENTAL; Interventions: Other: SCM and VSSP | Intervention Type: OTHER; Name: SCM; Assigned to Arm(s): SCM | Intervention Type: OTHER; Name: SCM and VSSP; Assigned to Arm(s): SCM and VSSP

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Comparison of Short Interval vs. Routine Postpartum Visit on Contraceptive Initiation
Brief Summary: The current postpartum care model of a single visit 4-6 weeks after delivery does not optimally address contraceptive needs. By this visit, many women have resumed sexual activity, potentially putting them at risk for unintended and rapid repeat pregnancy. In addition, many women with pregnancy-related Medicaid lose insurance coverage at this time, making it difficult to obtain long-acting reversible contraception (LARC) if desired. Therefore, an earlier postpartum visit may remove barriers to improve access to LARC thereby, reducing unintended and rapid repeat pregnancy. Our primary objective is to determine whether an additional 3-week postpartum visit, compared to usual postpartum care, will affect the initiation of LARC by 6 weeks postpartum.


Options:
A: Arm Label: New breastfeeding programme; Type: EXPERIMENTAL; Interventions: Other: New Breastfeeding Counselling | Arm Label: Treatment as usual; Type: ACTIVE_COMPARATOR; Interventions: Other: Treatment as usual | Intervention Type: OTHER; Name: New Breastfeeding Counselling; Assigned to Arm(s): New breastfeeding programme | Intervention Type: OTHER; Name: Treatment as usual; Assigned to Arm(s): Treatment as usual
B: Intervention Type: BEHAVIORAL; Name: Home Nurse Visit; Assigned to Arm(s): N/A
C: Arm Label: 3-week visit; Type: EXPERIMENTAL; Interventions: Other: 3-week visit | Arm Label: usual care; Type: ACTIVE_COMPARATOR; Interventions: Other: usual care | Intervention Type: OTHER; Name: 3-week visit; Assigned to Arm(s): 3-week visit | Intervention Type: OTHER; Name: usual care; Assigned to Arm(s): usual care
D: Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Relaxation; Type: EXPERIMENTAL; Interventions: Behavioral: Relaxation | Intervention Type: BEHAVIORAL; Name: Relaxation; Assigned to Arm(s): Relaxation

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Comparison of Short Interval vs. Routine Postpartum Visit on Contraceptive Initiation
Brief Summary: The current postpartum care model of a single visit 4-6 weeks after delivery does not optimally address contraceptive needs. By this visit, many women have resumed sexual activity, potentially putting them at risk for unintended and rapid repeat pregnancy. In addition, many women with pregnancy-related Medicaid lose insurance coverage at this time, making it difficult to obtain long-acting reversible contraception (LARC) if desired. Therefore, an earlier postpartum visit may remove barriers to improve access to LARC thereby, reducing unintended and rapid repeat pregnancy. Our primary objective is to determine whether an additional 3-week postpartum visit, compared to usual postpartum care, will affect the initiation of LARC by 6 weeks postpartum.


Options:
A: Arm Label: 3-week visit; Type: EXPERIMENTAL; Interventions: Other: 3-week visit | Arm Label: usual care; Type: ACTIVE_COMPARATOR; Interventions: Other: usual care | Intervention Type: OTHER; Name: 3-week visit; Assigned to Arm(s): 3-week visit | Intervention Type: OTHER; Name: usual care; Assigned to Arm(s): usual care
B: Intervention Type: BEHAVIORAL; Name: Home Nurse Visit; Assigned to Arm(s): N/A
C: Arm Label: mci guidance & peer social support; Type: EXPERIMENTAL; Interventions: Behavioral: mci guidance peer support | Arm Label: peer social support; Type: SHAM_COMPARATOR; Interventions: Behavioral: mci guidance peer support | Intervention Type: BEHAVIORAL; Name: mci guidance peer support; Assigned to Arm(s): mci guidance & peer social support, peer social support
D: Arm Label: Postpartum Visit 3-4 Weeks; Type: EXPERIMENTAL; Interventions: Behavioral: Postpartum Visit 3-4 Weeks | Arm Label: Postpartum Visit 6-8 Weeks; Type: EXPERIMENTAL; Interventions: Behavioral: Postpartum Visit 6-8 Weeks | Intervention Type: BEHAVIORAL; Name: Postpartum Visit 3-4 Weeks; Assigned to Arm(s): Postpartum Visit 3-4 Weeks | Intervention Type: BEHAVIORAL; Name: Postpartum Visit 6-8 Weeks; Assigned to Arm(s): Postpartum Visit 6-8 Weeks

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Stroke Avoidance for Children in REpublica Dominicana (SACRED): A Prospective Research Study to Reduce Stroke in Children With Sickle Cell Anemia
Brief Summary: Prospective screening and treatment study for children with Sickle Cell Anemia and increased stroke risk living in the Dominican Republic.


Options:
A: Intervention Type: PROCEDURE; Name: blood transfusion; Assigned to Arm(s): N/A
B: Arm Label: Longitudinal Portion; Type: EXPERIMENTAL; Interventions: Procedure: TCD examination | Arm Label: Treatment Phase; Type: EXPERIMENTAL; Interventions: Drug: Hydroxyurea, Procedure: TCD examination | Intervention Type: DRUG; Name: Hydroxyurea; Assigned to Arm(s): Treatment Phase | Intervention Type: PROCEDURE; Name: TCD examination; Assigned to Arm(s): Longitudinal Portion, Treatment Phase
C: Arm Label: Hydroxyurea Treatment; Type: EXPERIMENTAL; Interventions: Drug: Hydroxyurea | Intervention Type: DRUG; Name: Hydroxyurea; Assigned to Arm(s): Hydroxyurea Treatment
D: Arm Label: Transfusion Group; Type: ACTIVE_COMPARATOR; Interventions: Procedure: transfusion therapy | Arm Label: Observation Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: PROCEDURE; Name: transfusion therapy; Assigned to Arm(s): Transfusion Group

Answer: B