TrialPanorama/Dataset huggingface dataset:
Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Effect of Remote Ischaemic Preconditioning and Glyceryl Trinitrate on Peri-operative Myocardial Injury in Cardiac Bypass Surgery Patients (ERIC-GTN Study)
Brief Summary: The purpose of this study is to determine whether Glyceryl Trinitrate (GTN) reduces injury to the heart during heart-lung bypass surgery in combination with the newer technique of remote ischaemic preconditioning (RIPC).


Options:
A: Inclusion Criteria:

* Age \> 18 years all patients admitted for on- pump CABG and/or valve surgery
* Able to give consent

Exclusion Criteria:

* Allergies to excipients of IMP and placebo
* Chronic Renal failure (eGFR\<30 ml/min/kg)
* Severe liver disease
* Peripheral arterial disease
* Pregnant or lactating women
B: Inclusion Criteria:

* Adult patients undergoing elective CABG surgery

Exclusion Criteria:

* \<18 years old
* Significant renal or hepatic disease
* Previous acute myocardial infarction (within 4 weeks)
C: Inclusion Criteria:

* patients undergoing heart surgery on cardiopulmonary bypass

Exclusion Criteria:

* age \< 18
* Emergency cases
* left ventricular ejection fraction less than 30%
* current atrial fibrillation
* Inability to give informed consent
* preoperative use of inotropics or mechanical assist device
* severe liver, renal and pulmonary disease
* recent myocardial infarction (within 7 days)
* recent systemic infection or sepsis (within 7 days)
* severe stroke (within 2 months)
* peripheral vascular disease affecting upper limbs
* previous serious psychiatric disorders (e.g. schizophrenia, dementia)
* concomitant carotid endarterectomy
* rare surgeries: cardiac transplantation, correction of complicated congenital anomalies, pulmonary thromboembolectomy, off-pump surgery, minimal-invasive operation without sternotomy
D: Inclusion Criteria:

1. Patients undergoing CABG with or without valve surgery using blood cardioplegia
2. Patients aged 18 years and above
3. Patients with an additive Euroscore greater than or equal to 5

Exclusion Criteria:

1. Cardiogenic shock
2. Cardiac arrest on current admission
3. Pregnancy
4. Significant peripheral arterial disease affecting the upper limbs
5. Patients with significant hepatic dysfunction (Prothrombin\>2.0 ratio)
6. Patients with significant pulmonary disease (FEV1\<40% predicted)
7. Patients with known renal failure with a GFR\<30 mL/min/1.73 m2
8. Patients on glibenclamide or nicorandil, as these medications may interfere with RIC
9. Patients recruited into another study which may impact on the ERICCA study

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Open Abdomen: Vacuum Pack Versus Sylo Bag and Mesh Protocol - A Randomized Trial
Brief Summary: The open abdomen is a valid and accepted surgical tactic for the trauma and acute care patient. There have been many mechanisms described for its management, but the most accepted strategy is the vacuum pack. At our hospital the investigators have used for many years a double sylo bag, one underneath the fascia and the other sutured to the skin, at the initial operation. At subsequent surgeries once the abdomen is clean the investigators leave the same subfascial sylo bag and use a prolene mesh attached to the fascia. Every day the investigators try to tighten the mesh with sutures until the abdomen can be closed. This study´s objective is to compare our double sylo bag- mesh protocol with the vacuum pack to determine which is related to a higher fascial closure rate.


Options:
A: Inclusion Criteria:

* Presence of purulent, feculent, or enteric spillage over at least 2 intra-peritoneal quadrants intra-operatively;
* Septic shock, or
* Predisposition-Infection-Response-Organ Dysfunction Score \> 3, or
* World-Society-of-Emergency-Surgery-Sepsis-Severity-Score \> 8

Exclusion Criteria:

* Pregnant;
* Confirmed or strongly suspected severe IAH (IAP\>20 mmHg);
* No intentional of providing ongoing care;
* pancreatitis as the source of peritonitis;
* uncontrolled bleeding
B: Inclusion Criteria:

* No age limit
* Indication to Open Abdomen
* Informed consent

Exclusion Criteria:

* Informed consent refusal
* No indication to Open Abdomen
C: Inclusion Criteria:

* Critically ill/injured requiring intensive care unit admission
* Decision regarding the need to utilize an open abdomen technique after the first laparotomy
* Age \> 18
* Non-pregnant

Exclusion Criteria:

* Decision to formally close the abdomen after the initial laparotomy
* Patients receiving intra-peritoneal chemotherapy
* Pregnancy
* Age \< 18
D: Inclusion Criteria:

* Open Abdomen

Exclusion Criteria:

* Patients that die in the first 48 hours after the initial intervention

Answer: D
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Post-abortion Care and Contraceptive Counselling by Midwives or Physicians - a Randomized Controlled Trial in Kisumu, Western Kenya
Brief Summary: The aim of this project is to study the safety, efficacy and effectiveness of medical treatment of incomplete abortion provided to women by physicians or midwives in Kisumu, Kenya.

In Kenya, Post Abortion Care (PAC), provided by physicians, nurse-midwives and clinical officers, has been integrated at private reproductive health facilities since 1998. Misoprostol as treatment of incomplete abortion was launched I Nyanza Province in April, 2012. The involvement of midwives in medical (Misoprostol) treatment of incomplete abortion has, however, not been systematically evaluated. There is a need to determine whether midwives and physician can perform medical treatment of incomplete abortion equally safe and effective in Kenya. The results will thus provide evidence-based information that can contribute to the development of strategies to increase women's access to Post Abortion Care in Kenya as well as in other low-income contexts.


Options:
A: Inclusion Criteria:

* Uterine size no larger than 12 weeks LMP at time of presentation for care.
* Past or present history of vaginal bleeding during pregnancy.
* Open cervical os.
* If ultrasound used evidence of incomplete abortion with substantial debris in the uterus.
* All women would have been advised to have surgical evacuation of the uterus if misoprostol was not available.
* General good health.
* Willing to provide contact information for purposes of follow-up.
* Also in Egypt: 21 years of age or over or parental permission (there is no minimum age requirement in Niger, Mauritania and Senegal).

Exclusion Criteria:

* Contraindications to study drug
* Signs of severe infection, defined as at least one of the following: 1) foul smelling discharge, 2) fever \> 38 degrees C , 3) uterine tenderness
* Hemodynamic disturbances (pulse \>110/min and systolic bp \<100)
* Have an IUD in place; (the IUD may be removed making the woman eligible)
* Suspected ectopic pregnancy
B: Inclusion Criteria:

* Women presenting with vaginal bleeding in the first trimester of pregnancy and diagnosed to have incomplete abortion

Exclusion Criteria:

* Women with unstable hemodynamic status and shock, signs of sepsis.
C: Inclusion Criteria:

* 14 and 24 weeks of gestation
* Both nulliparous and multiparous women
* An unfavorable cervix (Bishop's score less than 8)

Exclusion Criteria:

* Known contraindications to the use of prostaglandins (e.g. asthma)
* Previous uterine scar (previous cesarean or myomectomy where the endometrial cavity was entered)
D: Inclusion Criteria:

* bleeding and contractions during pregnancy

Exclusion Criteria:

* women with known allergy to misoprostol,
* a uterine size more than 12 weeks of gestation,
* suspected ectopic pregnancy,
* unstable hemodynamic status and chock,
* signs of pelvic infection and/or sepsis.

Answer: B
Please select the eligibility criteria that correspond to the clinical trial below.
Title: The PREMOD Trial: A Randomized Controlled Trial of Umbilical Cord Milking vs. Delayed Cord Clamping in Premature Infants
Brief Summary: Premature babies can be very sick and have bleeding in the brain. Giving babies more blood before cutting the umbilical cord by delayed cord clamping or umbilical cord milking has been shown to reduce the risk of bleeding in the brain. This may be related to improving perfusion to the brain. However, some studies suggest that delayed cord clamping may not increase hemoglobin or blood volume in babies delivered by cesarean section. Milking the umbilical cord may give more blood in babies delivered by Cesarean Section may improve perfusion and reduce bleeding in the brain.


Options:
A: Inclusion Criteria:

* Singleton or multiples pregnancies in patients admitted for medically indicated delivery or in advanced spontaneous preterm labor with imminent delivery at 23 0/7 - 31 6/7 weeks gestation

Exclusion Criteria:

* Planned vaginal breech delivery
* Major fetal abnormalities (defined as those that are lethal or require prenatal or postnatal surgery)
* Fetal death in utero
* Red cell isoimmunization
* Patients who are incapable of informed consent (unconscious, severely ill, mentally handicapped), or are unwilling to undergo randomization
* Placenta accreta or abruption
B: Inclusion Criteria:

* Late preterm or term pregnancy (gestational age 34 to 41 weeks)
* Vaginal delivery

Exclusion Criteria:

* Serious congenital malformation, syndrome or other congenital disease that can affect the outcome measures
C: Inclusion Criteria:

* Singleton pregnancies
* Signed consent to participate in the trial

Exclusion Criteria:

* Major fetal anomaly or known fetal chromosomal abnormalities
* Multiple gestation
* Mothers with pregestational and gestational diabetes
* Refusal to participate in the trial
D: Inclusion Criteria:

* Pregnant women delivering at study site hospital

Exclusion Criteria:

* Delivery by Cesarean section
* Pregnancy ≤ 36 or ≥ 42 weeks gestation
* Multiple gestation
* Diagnosis of any of the following in the current pregnancy: hemorrhage requiring clinic/hospital admission, placental abnormalities, fetal anomalies, Down's syndrome of the fetus
* Diagnosis of pre-eclampsia or eclampsia in current or previous pregnancies
* Diagnosis at any time for the mother of any of the following: Diabetes, hypertension, cardiopathies, chronic renal disease
* Infant with major congenital malformation
* Infant birth weight less than 2500 g
* Mother not planning to breast feed for at least 6 months
* Mother smoked during current pregnancy
* Unwilling to return for follow-up study visits at the hospital

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: TeleLifestyleCoaching Use of Telemedicine for Weight Loss and Care of Weight Associated Illnesses
Brief Summary: Lifestyle changes often fail due to loss of motivation. Telemedicine and personal coaching have the potential to support lifestyle change and weight loss. Therefore, the aim of our randomized controlled trial was to examine the effect of telemedicine with and without coaching in comparison to a control group on weight loss in overweight participants.


Options:
A: Inclusion Criteria:

* BMI ≥27 kg/m2

Exclusion Criteria:

* Hypoglycemia inducing medication
* severe disease with hospital stay during the last 3 months
* smoking cessation for less then 3 months
* planned smoking cessation during study phase
* acute infects
* chronic diseases
B: Inclusion Criteria:

* Adults between 21 and 65 years
* Sedentary (engaging in moderate intensity physical activity for less than 60 minutes per week)
* Working full time (35+ hours/week) at a sedentary desk dependant occupation
* Overweight (Body Mass Index \> 25.0 kg/m2 but less than 40.0 kg/2)
* Apparently healthy as assessed by a health history screening survey
* Devoid of overt complicated or acute cardiovascular, metabolic, respiratory, or neurological diseases
* Free from exercise/physical activity limitations

Exclusion Criteria:

* Adults with significant health problems exacerbated by exercise, such as uncontrolled hypertension, diabetes, orthopedic limitations, etc. will be excluded from the study. Note, with physician approval and adequate control of these health problems, these conditions will not necessarily preclude participation.
* Being unable to exercise
C: Inclusion Criteria:

* regional Northern California KP employees

Exclusion Criteria:

* none
D: Inclusion Criteria:

* Dutch speaking
* Age range: 18 - 65 years old
* Access to the Internet at work or at home

Answer: A
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Shoes for Kids on the Island of Pemba (SKIP): A Pragmatic, Cluster Randomised Controlled Trial to Test if Shoes Reduce Hookworm Infection and Transmission in School-aged Children on Pemba Island, Zanzibar
Brief Summary: Small association studies have hypothesised that shoes protect against hookworm infection. The purpose of this pragmatic study was determine, under field conditions, whether school-age children on Pemba Island, Zanzibar, would wear shoes and if shoes protected them against hookworm infection.


Options:
A: Inclusion Criteria:

Village level:

* Little existing sanitation coverage (\<10%)
* WaterAid and implementing partners expects normal scale up
* Stable and reasonably acceptable water supply
* No other WASH interventions planned or anticipated in next 30 months
* Reasonable year-round access by road to permit household visits by surveillance staff

Household level:

* Presence of a child\<4 or a pregnant woman
* Consent to participate
* Reside permanently in the village
B: Inclusion Criteria:

* Households in participating villages will be eligible to participate in the study if they have at least one child under 5 years.

Exclusion Criteria:

* None
C: Inclusion Criteria:

* school-aged children attending one of the 12 schools identified for the study

Exclusion Criteria:

* lack of consent from family
* allergy to Albendazole
D: Study Population Description:

The subject population will be young children and their mothers/guardians living in several contiguous districts of Western Province, in the rural areas outside the towns of Bungoma and Kakamega. Communities must meet the following criteria:

* Located in a rural area (defined as villages with \<25% residents living in rental houses, \<2 gas/petrol stations and \<10 shops)
* Not enrolled in ongoing WASH or nutrition programs
* No chlorine dispensers at water sources installed by programs separate from the present study
* Majority (\>80%) of households do not have access to piped water into the home
* At least six eligible pregnant women in the cluster at baseline.

From enrolled communities, household compounds will be enrolled if they meet the following criteria.

Inclusion Criteria:

1. One or more women who self-identify as pregnant at the time of the baseline survey
2. The woman plans to stay in the community for the next 12 months.

Exclusion Criteria:

(1) The study excludes households who do not own their home to help mitigate attrition during follow-up.

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: N/A
Brief Summary: Aim was to investigate efficacy of current treatments - water, chewing gum, and olive oil, in resolving postoperative ileus.


Options:
A: Inclusion Criteria:

* All out-patients \> 19 years old presenting for capsule endoscopy

Exclusion Criteria:

* Patients on narcotics
* Patients on motility enhancing and/or slowing drugs should stop these at least 5 days prior to the procedure or be excluded from the study.
* Patients, who have proven or suspected obstruction of the bowel.
* Patients, who have had prior small bowel and/or gastric surgery.
* Patients with an ileostomy.
* Patients who have a known and/or have a history of swallowing disorder
* Patients with diabetes and/or hypo-/hyper- thyroidism
* Patients in whom the capsule become impacted at a stricture (these patients will be taken out of the study and given the necessary medical/surgical treatment).
B: Inclusion Criteria:

* 18 years or older
* Undergoing benign gynecologic surgery via an exploratory laparotomy
* Capable of giving consent

Exclusion Criteria:

* Oromaxillary or mental disturbances that would make chewing gum dangerous with regards to mastication or aspiration
* Intubated or unconscious when leaving the OR
* Bowel resection performed at the time of surgery
* Active bowel disease (IBD, appendicitis, etc)
* Gynecologic malignancy
C: Inclusion Criteria:

* Patients underwent abdominal surgery for non neoplastic diseases

Exclusion Criteria:

* Metastatic disease
* History of inflammatory bowel disease
* Postoperative fever
* Gastrointestinal fistula
* Mint or olive allergy; and/or
* Earlier abdominal radiation
D: Inclusion Criteria:

* Patients scheduled for elective open or laparoscopic colectomy
* Age equal or greater than 18 years
* Informed consent

Exclusion Criteria:

* Participation in concurrent intervention trials
* Need for a stoma
* Known hypersensitivity or allergy to coffee
* Expected lack of compliance
* Impaired mental state or language problems
* change in surgical procedure

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Randomized, Placebo Controlled Trial of Indomethacin for Tocolysis
Brief Summary: Indomethacin for tocolysis for 48 hours vs placebo


Options:
A: Inclusion Criteria:

* Gestational age of 24+0 to 34+6weeks
* singleton and twin pregnancies
* preterm labor with more than 4 times of uterine contraction for 20 minutes or more than 8 times for 1 hour on external tocography
* cervical dilatation of 0 to 3cm and cervical ripening more than 25%, or cervical length in sonography below 2cm

Exclusion Criteria:

* triplet etc
* preterm premature rupture of membrane
* cervical dilatation more than 3cm
* history of cerclage operation during this pregnancy
* placenta previa
* severe hypertensive diseases in pregnancy
* history of administration of any tocolytics 12 hours before enrollment
* fever more than 38.0'c
B: Inclusion Criteria:

* pregnancy week 24-33
* Singleton pregnancy
* After successful treatment to stop PTL

Exclusion Criteria:

* Contraindications for Nifedipine extended release treatment.
C: Inclusion Criteria:

* Preterm labor as defined by regular uterine contractions (at least 6/hour) with cervical change of at least 1 cm or cervical shortening on transvaginal ultrasound less than 25mm of functional length
* Gestational age 23w0d to 31w6d weeks
* Singleton
* ≥ 18 years old
* Able to consent in English

Exclusion Criteria:

* Major congenital anomalies associated with an increased risk of newborn death
* Multiple fetal gestation (2+)
* Known intrauterine fetal demise
* Non-reassuring fetal status requiring delivery
* Preterm premature rupture of membranes (PPROM)
* Suspected or known intrauterine infection
* Placenta previa
* Maternal allergy or contraindication to indomethacin (peptic ulcer disease, thrombocytopenia, coagulopathy, renal or hepatic dysfunction)
* Inevitable delivery (cervix ≥6cm dilated)
D: Inclusion Criteria:

* Women included in the study were diagnosed as preterm labor defined according to American Academy of Pediatrics and the American College of Obstetricians and Gynecologists (2012) with regular contractions before 37 weeks that are associated with cervical change .

Regular uterine contractions means at least 4 in 20 minutes or 8 in 60 minutes) and cervical changes are either cervical dilation more than 1 cm, and/or cervical effacement ≥ 80%. Threatened preterm labour was defined as contractions without any appreciable cervical changes. Women included were between 18 and 40 years old at gestational age between 28 and 34 weeks

Exclusion Criteria:

* Women with failed tocolytic treatment to stop uterine contractions,
* those with established preterm labor (cervical dilatation ≥ 4 cm),
* multifetal pregnancy
* fetal anomalies
* those with contraindication of continuation of pregnancy (antepartum hemorrhage, premature rupture of membranes, evidence of intrauterine infections or non reassuring fetal heart rate tracing)

Answer: C
Please select the eligibility criteria that correspond to the clinical trial below.
Title: Effectiveness of an Educational Group Intervention in Primary Care to Maintain Exclusive Breastfeeding. Cluster Randomised Clinical Trial. PROLACT Study.
Brief Summary: Hypothesis: An educational intervention increases the proportion of mother-infant pairs using exclusive breastfeeding


Options:
A: Inclusion Criteria:

* 18 years or older, over 25 weeks pregnant, planning to breastfeed, lives with co-parent who is willing to participate, first time mother or mother who has not previously breastfed,

Exclusion Criteria:

* does not have access to the internet and telephone, does not reads and speaks English, does not lives in Ontario, Canada, is expecting more than one child with this pregnancy
B: Inclusion Criteria:

* Have just given birth (\<48 hours)
* Intention to breastfeed for 6 weeks
* Has daily access to a computer with internet
* Access to a phone
* Read and speak English
* Delivered a healthy singleton infant born \>37 weeks gestational age

Exclusion Criteria:

* Infants with congenital anomalies
* Mothers with major mental health issues (i.e Schizophrenia, Mania, Bipolar Disorder)
* Complications during delivery requiring intervention
* Mothers with major health issues that are not associated with pregnancy as determined by principal investigator (i.e. infection illness such as HIV+, hepatitis, diabetes, history of seizures, current diagnosis of cancer).
C: Inclusion Criteria:

* Female 18 years old or older,
* mother-infant pairs using exclusive breastfeeding,
* Signed Informed Consent

Exclusion Criteria:

* Any medical conditions that prevents breastfeeding
* infant should be not older than four weeks
D: Inclusion Criteria:

Aged 20 years and above. During the first or second trimester of pregnancy. Willing to breastfeed after delivery Singleton pregnancy. Participants are able to attend the breastfeeding class.

Exclusion Criteria:

Chronic medical conditions. Abnormal fetal screening. Preterm delivery before 37 weeks gestational weeks.

Answer: C