Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Virtual Reality Attention Training in Stroke Patients
Brief Summary: Hemispatial neglect is a post-stroke condition in which patients fail to detect stimuli presented on the side of space opposite to the damaged brain hemisphere (contralesional space). To date, there is no established effective treatment for this condition. A virtual reality (VR) behavioral training for the attention deficits characteristic of patients with hemispatial neglect was developed. Patients are stimulated in the visual and auditory modality to orient towards the contralesional side and are rewarded for detecting targets on this side in this training. In the current study the researchers aim to answer two main questions: 1) how feasible is a VR game-based intervention in stroke patients? and 2) what is the efficacy of the virtual reality game-based intervention in reducing the attention deficits characteristic of hemispatial neglect? To answer these questions a randomized partially double-blind placebo-controlled crossover study will be conducted. Two within-subject conditions will be compared: in the active condition patients will play a VR game in which multisensory stimulation is progressively presented in the neglected region (the location where previously presented targets were missed by the patient) and in the placebo condition patients will play a VR game in which the stimulation is presented in the center of of the VR environment. Neglect symptoms will be measured on a two-daily basis to establish the trend of symptom recovery through time. The hypothesis states that symptoms will recover more quickly when patients receive the active version of the VR intervention compared to the placebo version of the VR intervention.


Options:
A: Arm Label: Sham tDCS plus RTP; Type: SHAM_COMPARATOR; Interventions: Device: Sham tDCS | Arm Label: Active tDCS plus RTP; Type: ACTIVE_COMPARATOR; Interventions: Device: Active tDCS | Intervention Type: DEVICE; Name: Sham tDCS; Assigned to Arm(s): Sham tDCS plus RTP | Intervention Type: DEVICE; Name: Active tDCS; Assigned to Arm(s): Active tDCS plus RTP
B: Arm Label: Group A; Type: EXPERIMENTAL; Interventions: Behavioral: Active Intervention, Behavioral: Placebo Intervention | Arm Label: Group B; Type: EXPERIMENTAL; Interventions: Behavioral: Active Intervention, Behavioral: Placebo Intervention | Intervention Type: BEHAVIORAL; Name: Active Intervention; Assigned to Arm(s): Group A, Group B | Intervention Type: BEHAVIORAL; Name: Placebo Intervention; Assigned to Arm(s): Group A, Group B
C: Arm Label: Vibration to upper posterior neck muscles; Type: EXPERIMENTAL; Interventions: Other: Vibration to upper posterior neck muscles | Arm Label: Standard of care; Type: ACTIVE_COMPARATOR; Interventions: Other: Standard of Care | Intervention Type: OTHER; Name: Vibration to upper posterior neck muscles; Assigned to Arm(s): Vibration to upper posterior neck muscles | Intervention Type: OTHER; Name: Standard of Care; Assigned to Arm(s): Standard of care
D: Arm Label: Prism Adaptation Treatment; Type: EXPERIMENTAL; Interventions: Behavioral: Prism Adaptation Treatment | Arm Label: Control: Standard Rehabilitation Care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Prism Adaptation Treatment; Assigned to Arm(s): Prism Adaptation Treatment

Answer: B