Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Pilot Study of Central Meditation and Imagery Therapy for Borderline Personality Disorder
Brief Summary: Borderline personality disorder is a severe psychiatric disorder marked by emotional instability, difficulty with interpersonal relationships, and self-harming behaviors. Despite receiving psychotherapy for borderline personality disorder, studies show that patient recovery is slow, and there is a high rate of self injury and suicide attempts early in treatment. There is thus a clear need to provide therapies to augment psychotherapy. We will conduct a pilot trial to determine whether a 6-week Central Meditation and Imagery Therapy (CMIT) is feasible for subjects with borderline personality disorder to undergo when added on to psychotherapy treatment. CMIT is a non-validated therapy that combines principles of mindfulness with meditation techniques and guided imagery. Sessions led by a trained clinician in a group setting once a week, and participants are asked to complete daily home practice.

The trial will involve 16 participants, all currently undergoing psychotherapy for borderline personality disorder. Participants will be randomly assigned to either a CMIT group that lasts 6 weeks, or a wait list group. Those in the wait list group will be able to receive CMIT after 6 weeks. All participants will continue to receive psychotherapy throughout the trial.

During the trial, we will also obtain preliminary data to help understand whether CMIT may result in psychological benefits for participants. This will include measuring the pulse in order to determine variation in beat to beat intervals of the heart during psychological tests, and filling out questionnaires before and after participation in CMIT.


Options:
A: Arm Label: F-SPS Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: F-SPS+UC | Arm Label: Enhanced Usual Care (EUC); Type: ACTIVE_COMPARATOR; Interventions: Behavioral: EUC | Intervention Type: BEHAVIORAL; Name: F-SPS+UC; Assigned to Arm(s): F-SPS Intervention | Intervention Type: BEHAVIORAL; Name: EUC; Assigned to Arm(s): Enhanced Usual Care (EUC)
B: Arm Label: Compassion meditation (CM); Type: EXPERIMENTAL; Interventions: Behavioral: Compassion meditation (CM) | Arm Label: Support group (SG); Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Support group (SG) | Intervention Type: BEHAVIORAL; Name: Compassion meditation (CM); Assigned to Arm(s): Compassion meditation (CM) | Intervention Type: BEHAVIORAL; Name: Support group (SG); Assigned to Arm(s): Support group (SG)
C: Arm Label: Brexpiprazole 2-3 Milligrams Per Day; Type: EXPERIMENTAL; Interventions: Drug: Brexpiprazole | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: Placebo | Intervention Type: DRUG; Name: Brexpiprazole; Assigned to Arm(s): Brexpiprazole 2-3 Milligrams Per Day | Intervention Type: OTHER; Name: Placebo; Assigned to Arm(s): Placebo
D: Arm Label: meditation; Type: EXPERIMENTAL; Interventions: Behavioral: Central Meditation and Imagery Therapy | Arm Label: wait list; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Central Meditation and Imagery Therapy; Assigned to Arm(s): meditation

Answer: D