Please select the eligibility criteria that correspond to the clinical trial below.
Title: Community-based Rehabilitation Training After Stroke: a Pilot Randomised Controlled Trial
Brief Summary: A pilot study that will evaluate the feasibility and acceptability of procedures to inform the design and delivery of a definitive RCT of ReTrain (which would assess the clinical and cost effectiveness of ReTrain for stroke survivors).


Options:
A: Inclusion Criteria:

* patients with hemiplegia following a first unilateral stroke
* will score at least level 3 on the Functional Ambulation Category (FAC) (able to walk unaided on even ground but requiring verbal prompts and stand-by help without body contact)
* must have been independent walkers prior to insult without walking aids
* Subjects will have a Mini Mental State score of 22 or above

Exclusion Criteria:

* orthopaedic or other neurological conditions that could limit walking ability
* no gross visuospatial or visual field deficits
* no medical contraindications to walking
B: Inclusion Criteria:

* Primary clinical diagnosis of stroke (assessed by referring clinician/GP records)
* \>1 month (but no upper limit) since discharge from NHS physical rehabilitation services at randomisation
* Able to walk independently indoors with or without mobility aids, but has self-reported difficulty or requires help on stairs, slopes or uneven surfaces (assessed by recruiting team using standard tools)
* Willingness to be randomised to either control or ReTrain (and attend the training venue)
* Cognitive capacity and communication ability sufficient to participate in the study (assessed by recruiting team using standard tools).24 NB: Criterion (3) has been selected pragmatically to maximise eligibility while ensuring participants have a mobility deficit that could be addressed by the intervention. Eligible people with aphasia will not be excluded.

Exclusion Criteria:

* \<18 years old
* Contraindications to moderate to vigorous physical activity. Used in GP screening assessment form. (Adapted from ACSM guidelines 25) Contraindications include:

  * Acute or uncontrolled heart failure
  * Unstable or uncontrolled angina
  * Uncontrolled cardiac dysrhythmia causing symptoms or haemodynamic compromise
  * Symptomatic severe aortic stenosis
  * Current deep vein thrombosis, pulmonary embolus or pulmonary infarction
  * Acute myocarditis or pericarditis
  * Suspected or known dissecting aneurysm
  * Unstable / uncontrolled blood pressure
  * Systolic blood pressure \> 160
  * Diastolic blood pressure \> 100
  * Acute systemic infection
  * Uncontrolled diabetes
C: Inclusion Criteria:

* First CVA according to the WHO definition (A primary, first ever stroke ash revealed by rapidly developing clinical signs or focal or global disturbance or cerebral function, with symptoms lasting 24 hours or longer or leading to death, with no apparent cause other than or vascular origin.) This includes ischemic infarct or an intracerebral haemorrhage
* The offense can be maximum 3 up to 6 weeks after onset
* Patient must be able to follow simple verbal instructions
* To cycle during 1 minute at 20 Watt, 50RPM,
* Cardiac stable

Exclusion Criteria:

* Have another neurological impairments with permanent damage such as former cranial trauma, multiple sclerosis, epileptic status... which already present were for current CVA
* Having on CVA resembling symptoms as a result of subdural haemorrhage, a tumour, encephalitis or a trauma
* Barthel index \< 50 before the stroke onset
* Age \> 80 year
* No authorisation form of the patient or of the family
* Absolute contra-indications for effort test (ACC/AHA guidelines)
D: Inclusion Criteria:

* single unilateral stroke
* discharged from active rehabilitation
* the ability to walk independently, with or without using an aid or orthosis
* the ability to comprehend instruction

Exclusion Criteria:

* a history of serious cardiac disease (e.g. myocardial infarction, unstable angina) in the previous six months
* uncontrolled blood pressure
* significant neurological or musculoskeletal conditions in addition to stroke
* currently participating in another clinical trial (rehabilitation or pharmacological)

Answer: B