Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A 12-month, Open Label, Randomised, Effectiveness Study to Evaluate Fluticasone Furoate (FF, GW685698)/Vilanterol (VI, GW642444) Inhalation Powder Delivered Once Daily Via a Novel Dry Powder Inhaler Compared With Usual Maintenance Therapy in Subjects With Asthma
Brief Summary: This study is designed to compare the effectiveness and safety of Fluticasone Furoate/Vilanterol Inhalation Powder (100mcg Fluticasone Furoate ((FF), GW685698)/25mcg Vilanterol ((VI), GW642444) or 200mcg Fluticasone Furoate ((FF), GW685698)/25mcg Vilanterol ((VI), GW642444) ) delivered once daily via a Novel Dry Powder Inhaler (NDPI) compared with the existing asthma maintenance therapy over twelve months in subjects diagnosed with asthma. This is a Phase III multi-centre, randomised open label study. Subjects who meet the eligibility criteria are randomised and will enter a 12 month treatment period.


Options:
A: Arm Label: FF/VI; Type: EXPERIMENTAL; Interventions: Drug: fluticasone furoate + vilanterol, Drug: inhaled corticosteroid with or without a long acting beta2-agonist | Arm Label: ICS or ICS/LABA maintenance therapy; Type: ACTIVE_COMPARATOR; Interventions: Drug: inhaled corticosteroid with or without a long acting beta2-agonist | Intervention Type: DRUG; Name: fluticasone furoate + vilanterol; Assigned to Arm(s): FF/VI | Intervention Type: DRUG; Name: inhaled corticosteroid with or without a long acting beta2-agonist; Assigned to Arm(s): FF/VI, ICS or ICS/LABA maintenance therapy
B: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo, Drug: Fluticasone Furoate, Drug: Albuterol/salbutamol | Arm Label: UMEC 62.5 mcg; Type: EXPERIMENTAL; Interventions: Drug: UMEC, Drug: Fluticasone Furoate, Drug: Albuterol/salbutamol | Arm Label: UMEC 31.25 mcg; Type: EXPERIMENTAL; Interventions: Drug: UMEC, Drug: Fluticasone Furoate, Drug: Albuterol/salbutamol | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo | Intervention Type: DRUG; Name: UMEC; Assigned to Arm(s): UMEC 31.25 mcg, UMEC 62.5 mcg | Intervention Type: DRUG; Name: Fluticasone Furoate; Assigned to Arm(s): Placebo, UMEC 31.25 mcg, UMEC 62.5 mcg | Intervention Type: DRUG; Name: Albuterol/salbutamol; Assigned to Arm(s): Placebo, UMEC 31.25 mcg, UMEC 62.5 mcg
C: Arm Label: QVM149 150/50/160 µg o.d.; Type: EXPERIMENTAL; Interventions: Drug: QVM149 150/50/160 | Arm Label: QVM149 150/50/80 µg o.d.; Type: EXPERIMENTAL; Interventions: Drug: QVM149 150/50/80 | Arm Label: QMF149 150/320 µg o.d.; Type: ACTIVE_COMPARATOR; Interventions: Drug: QMF149 150/320 | Arm Label: QMF149 150/160 µg o.d.; Type: ACTIVE_COMPARATOR; Interventions: Drug: QMF149 150/160 | Arm Label: Salmeterol/fluticasone 50/500 μg b.i.d.; Type: ACTIVE_COMPARATOR; Interventions: Drug: salmeterol/fluticasone | Intervention Type: DRUG; Name: QVM149 150/50/160; Assigned to Arm(s): QVM149 150/50/160 µg o.d. | Intervention Type: DRUG; Name: QVM149 150/50/80; Assigned to Arm(s): QVM149 150/50/80 µg o.d. | Intervention Type: DRUG; Name: QMF149 150/320; Assigned to Arm(s): QMF149 150/320 µg o.d. | Intervention Type: DRUG; Name: QMF149 150/160; Assigned to Arm(s): QMF149 150/160 µg o.d. | Intervention Type: DRUG; Name: salmeterol/fluticasone; Assigned to Arm(s): Salmeterol/fluticasone 50/500 μg b.i.d.
D: Arm Label: Fluticasone furoate/Vilanterol (GW642444); Type: EXPERIMENTAL; Interventions: Drug: Fluticasone furoate/Vilanterol Inhalation Powder | Arm Label: Fluticasone Furoate; Type: EXPERIMENTAL; Interventions: Drug: Fluticasone Furoate Inhalation Powder | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo Inhaltion Powder | Intervention Type: DRUG; Name: Fluticasone furoate/Vilanterol Inhalation Powder; Assigned to Arm(s): Fluticasone furoate/Vilanterol (GW642444) | Intervention Type: DRUG; Name: Fluticasone Furoate Inhalation Powder; Assigned to Arm(s): Fluticasone Furoate | Intervention Type: DRUG; Name: Placebo Inhaltion Powder; Assigned to Arm(s): Placebo

Answer: A