TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Re-Entry MTC for Offenders With MICA Disorders
Brief Summary: The purpose of this study is to examine the transition of offenders with both mental illness and chemical abuse (MICA) disorders from prison to the community, where continued treatment is generally considered necessary to sustain gains made by prison treatment, and to achieve successful outcomes. The project will determine the effectiveness of a modified therapeutic community (Re-Entry MTC) approach as compared to the case management and parole supervision currently provided. The study will also assess the relative impact on treatment outcomes of the type of treatment received while in prison and of the progress achieved in re-entry treatment.


Options:
A: Arm Label: Intramuscular naltrexone; Type: ACTIVE_COMPARATOR; Interventions: Drug: Vivitrol- Intramuscular naltrexone (depot-formulation) | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Vivitrol- Intramuscular naltrexone (depot-formulation); Assigned to Arm(s): Intramuscular naltrexone | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
B: Arm Label: Re-entry Modified Therapeutic Community (Re-entry MTC); Type: EXPERIMENTAL; Interventions: Behavioral: Re-entry Modified Therapeutic Community (Re-entry MTC) | Arm Label: Parole Supervision and Case Management; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Parole Supervision and Case Management | Intervention Type: BEHAVIORAL; Name: Re-entry Modified Therapeutic Community (Re-entry MTC); Assigned to Arm(s): Re-entry Modified Therapeutic Community (Re-entry MTC) | Intervention Type: BEHAVIORAL; Name: Parole Supervision and Case Management; Assigned to Arm(s): Parole Supervision and Case Management
C: Intervention Type: BIOLOGICAL; Name: MN rgp120/HIV-1 and A244 rgp120/HIV-1; Assigned to Arm(s): N/A
D: Arm Label: Methylphenidate; Type: EXPERIMENTAL; Interventions: Drug: PR OROS Methylphenidate | Arm Label: Sugar pill; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: PR OROS Methylphenidate; Assigned to Arm(s): Methylphenidate | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Sugar pill

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Trial of Immunological Outcomes of Sublingual Immunotherapy for House Dust Mite (D. Pteronyssinus) Allergy
Brief Summary: Allergic diseases represent a major health issue worldwide. Mainstay treatment is allergen avoidance and pharmacotherapy for symptom relief. Allergen immunotherapy offers the advantages of specific treatment with long lasting efficacy, and can modify the course of disease. However, use of this treatment is restricted by the high risk of adverse events especially in asthmatics. Other, better tolerated, routes of allergen administration than the current conventional subcutaneous route (SCIT) have been investigated including sublingual (SLIT). However, the immune parameters of SLIT have not been examined. We propose conducting a randomised, placebo-controlled study of a commercially-available SLIT for house dust mite (HDM) allergy to investigate induction of relevant T cell regulatory immune mechanisms. The first year will be followed by an optional open label extension period. Immunoregulatory cytokine synthesis and T cell phenotype and function (real time PCR and flow cytometry) will be examined. This project will provide important fundamental knowledge on which to base improved and greater application of this potentially curative treatment for allergy. SLIT has the potential advantage of home administration and suitability for patients with asthma who are currently unable to access many of the allergen desensitising regimens.


Options:
A: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: MK-8237 6 Developmental Units (DU); Type: EXPERIMENTAL; Interventions: Drug: MK-8237 6 DU | Arm Label: MK-8237 12 DU; Type: EXPERIMENTAL; Interventions: Drug: MK-8237 12 DU | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo | Intervention Type: DRUG; Name: MK-8237 6 DU; Assigned to Arm(s): MK-8237 6 Developmental Units (DU) | Intervention Type: DRUG; Name: MK-8237 12 DU; Assigned to Arm(s): MK-8237 12 DU
B: Arm Label: Immunotherapy; Type: EXPERIMENTAL; Interventions: Biological: Grass pollen allergens in a water/glycerol solution | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: BIOLOGICAL; Name: Grass pollen allergens in a water/glycerol solution; Assigned to Arm(s): Immunotherapy | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
C: Intervention Type: DRUG; Name: ALK HDM tablet; Assigned to Arm(s): N/A
D: Arm Label: 1; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Drug: (agent for immunotherapy) Staloral | Intervention Type: DRUG; Name: (agent for immunotherapy) Staloral; Assigned to Arm(s): 2 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): 1

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Trial of Immunological Outcomes of Sublingual Immunotherapy for House Dust Mite (D. Pteronyssinus) Allergy
Brief Summary: Allergic diseases represent a major health issue worldwide. Mainstay treatment is allergen avoidance and pharmacotherapy for symptom relief. Allergen immunotherapy offers the advantages of specific treatment with long lasting efficacy, and can modify the course of disease. However, use of this treatment is restricted by the high risk of adverse events especially in asthmatics. Other, better tolerated, routes of allergen administration than the current conventional subcutaneous route (SCIT) have been investigated including sublingual (SLIT). However, the immune parameters of SLIT have not been examined. We propose conducting a randomised, placebo-controlled study of a commercially-available SLIT for house dust mite (HDM) allergy to investigate induction of relevant T cell regulatory immune mechanisms. The first year will be followed by an optional open label extension period. Immunoregulatory cytokine synthesis and T cell phenotype and function (real time PCR and flow cytometry) will be examined. This project will provide important fundamental knowledge on which to base improved and greater application of this potentially curative treatment for allergy. SLIT has the potential advantage of home administration and suitability for patients with asthma who are currently unable to access many of the allergen desensitising regimens.


Options:
A: Arm Label: SLIT; Type: EXPERIMENTAL; Interventions: Biological: sublingual immunotherapy | Arm Label: placebo; Type: PLACEBO_COMPARATOR; Interventions: Biological: placebo | Intervention Type: BIOLOGICAL; Name: sublingual immunotherapy; Assigned to Arm(s): SLIT | Intervention Type: BIOLOGICAL; Name: placebo; Assigned to Arm(s): placebo
B: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Drug: Staloral | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Drug: Staloral | Intervention Type: DRUG; Name: Staloral; Assigned to Arm(s): 1, 2
C: Arm Label: 1; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Drug: (agent for immunotherapy) Staloral | Intervention Type: DRUG; Name: (agent for immunotherapy) Staloral; Assigned to Arm(s): 2 | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): 1
D: Intervention Type: BIOLOGICAL; Name: Recombinant birch pollen; Assigned to Arm(s): N/A

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Randomized, Double-Blind, Active-Comparator-Controlled, Parallel-Group Study to Evaluate the Safety of Etoricoxib in Patients With Osteoarthritis or Rheumatoid Arthritis
Brief Summary: The study is designed to compare the risk of cardiovascular events (heart attacks, strokes) in patients receiving either etoricoxib or diclofenac. It will also compare the gastrointestinal tolerability of the two medicines. The study will be conducted in patients with either rheumatoid or osteo-arthritis.


Options:
A: Intervention Type: DRUG; Name: MK0663, etoricoxib; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Comparator: Diclofenac sodium; Assigned to Arm(s): N/A
B: Arm Label: A; Type: EXPERIMENTAL; Interventions: Drug: Celecoxib | Arm Label: B; Type: ACTIVE_COMPARATOR; Interventions: Drug: Diclofenac + Omeprazole | Intervention Type: DRUG; Name: Celecoxib; Assigned to Arm(s): A | Intervention Type: DRUG; Name: Diclofenac + Omeprazole; Assigned to Arm(s): B
C: Intervention Type: DRUG; Name: MK0663, etoricoxib; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Comparator: Diclofenac sodium; Assigned to Arm(s): N/A
D: Intervention Type: DRUG; Name: MK0663, etoricoxib; Assigned to Arm(s): N/A | Intervention Type: DRUG; Name: Comparator: Diclofenac sodium; Assigned to Arm(s): N/A

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: New Moves: Obesity Prevention Among Adolescent Girls
Brief Summary: The New Moves study will evaluate the impact of a school based program for inactive high school girls who are overweight or at risk for being overweight due to low levels of physical activity. The primary study hypothesis is that girls in the intervention schools will significantly decrease their percent body fat as compared to girls in the control schools. Secondary research hypotheses include that girls in the intervention condition will significantly increase their physical activity levels and improve the quality of their dietary intake.


Options:
A: Arm Label: Walking/Running Program; Type: EXPERIMENTAL; Interventions: Behavioral: Walking/Running program | Arm Label: Classroom activity break program; Type: EXPERIMENTAL; Interventions: Behavioral: Classroom physical activity break program | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Walking/Running program; Assigned to Arm(s): Walking/Running Program | Intervention Type: BEHAVIORAL; Name: Classroom physical activity break program; Assigned to Arm(s): Classroom activity break program
B: Arm Label: Physical activity; Type: EXPERIMENTAL; Interventions: Behavioral: Physical activity | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Physical activity; Assigned to Arm(s): Physical activity
C: Arm Label: New Moves Intervention Group; Type: EXPERIMENTAL; Interventions: Behavioral: New Moves | Arm Label: control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: New Moves; Assigned to Arm(s): New Moves Intervention Group
D: Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: The StepSmart Challenge | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: The StepSmart Challenge; Assigned to Arm(s): Intervention

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: New Moves: Obesity Prevention Among Adolescent Girls
Brief Summary: The New Moves study will evaluate the impact of a school based program for inactive high school girls who are overweight or at risk for being overweight due to low levels of physical activity. The primary study hypothesis is that girls in the intervention schools will significantly decrease their percent body fat as compared to girls in the control schools. Secondary research hypotheses include that girls in the intervention condition will significantly increase their physical activity levels and improve the quality of their dietary intake.


Options:
A: Arm Label: Low intensity arm; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Dietary, physical activity and sleeping | Arm Label: High intensity arm; Type: EXPERIMENTAL; Interventions: Behavioral: Dietary, physical activity and sleeping | Intervention Type: BEHAVIORAL; Name: Dietary, physical activity and sleeping; Assigned to Arm(s): High intensity arm, Low intensity arm
B: Arm Label: New Moves Intervention Group; Type: EXPERIMENTAL; Interventions: Behavioral: New Moves | Arm Label: control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: New Moves; Assigned to Arm(s): New Moves Intervention Group
C: Arm Label: HIP; Type: EXPERIMENTAL; Interventions: Other: HIP | Arm Label: Non-HIP; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: HIP; Assigned to Arm(s): HIP
D: Intervention Type: BEHAVIORAL; Name: diet, reducing; Assigned to Arm(s): N/A

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: New Moves: Obesity Prevention Among Adolescent Girls
Brief Summary: The New Moves study will evaluate the impact of a school based program for inactive high school girls who are overweight or at risk for being overweight due to low levels of physical activity. The primary study hypothesis is that girls in the intervention schools will significantly decrease their percent body fat as compared to girls in the control schools. Secondary research hypotheses include that girls in the intervention condition will significantly increase their physical activity levels and improve the quality of their dietary intake.


Options:
A: Arm Label: School-based intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Trial of Activity for Adolescent Girls (TAAG) | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Trial of Activity for Adolescent Girls (TAAG); Assigned to Arm(s): School-based intervention
B: Intervention Type: BEHAVIORAL; Name: physical exercise; Assigned to Arm(s): N/A
C: Arm Label: After school sports; Type: EXPERIMENTAL; Interventions: Behavioral: After school sports program | Arm Label: After school health education; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: After school health education | Intervention Type: BEHAVIORAL; Name: After school sports program; Assigned to Arm(s): After school sports | Intervention Type: BEHAVIORAL; Name: After school health education; Assigned to Arm(s): After school health education
D: Arm Label: New Moves Intervention Group; Type: EXPERIMENTAL; Interventions: Behavioral: New Moves | Arm Label: control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: New Moves; Assigned to Arm(s): New Moves Intervention Group

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: New Moves: Obesity Prevention Among Adolescent Girls
Brief Summary: The New Moves study will evaluate the impact of a school based program for inactive high school girls who are overweight or at risk for being overweight due to low levels of physical activity. The primary study hypothesis is that girls in the intervention schools will significantly decrease their percent body fat as compared to girls in the control schools. Secondary research hypotheses include that girls in the intervention condition will significantly increase their physical activity levels and improve the quality of their dietary intake.


Options:
A: Arm Label: New Moves Intervention Group; Type: EXPERIMENTAL; Interventions: Behavioral: New Moves | Arm Label: control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: New Moves; Assigned to Arm(s): New Moves Intervention Group
B: Arm Label: Arm 1; Type: EXPERIMENTAL; Interventions: Behavioral: Primary (Environmental) Weight Gain Prevention | Arm Label: Arm 2; Type: EXPERIMENTAL; Interventions: Behavioral: Primary (Environmental) Weight Gain Prevention, Behavioral: Secondary (Behavioral) Weight Gain Prevention | Arm Label: Arm 3; Type: EXPERIMENTAL; Interventions: Behavioral: Control | Intervention Type: BEHAVIORAL; Name: Primary (Environmental) Weight Gain Prevention; Assigned to Arm(s): Arm 1, Arm 2 | Intervention Type: BEHAVIORAL; Name: Secondary (Behavioral) Weight Gain Prevention; Assigned to Arm(s): Arm 2 | Intervention Type: BEHAVIORAL; Name: Control; Assigned to Arm(s): Arm 3
C: Arm Label: Intervention group; Type: EXPERIMENTAL; Interventions: Behavioral: Sleep hygiene counseling | Arm Label: Control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Sleep hygiene counseling; Assigned to Arm(s): Intervention group
D: Arm Label: BALANCE; Type: EXPERIMENTAL; Interventions: Behavioral: BALANCE | Intervention Type: BEHAVIORAL; Name: BALANCE; Assigned to Arm(s): BALANCE

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: New Moves: Obesity Prevention Among Adolescent Girls
Brief Summary: The New Moves study will evaluate the impact of a school based program for inactive high school girls who are overweight or at risk for being overweight due to low levels of physical activity. The primary study hypothesis is that girls in the intervention schools will significantly decrease their percent body fat as compared to girls in the control schools. Secondary research hypotheses include that girls in the intervention condition will significantly increase their physical activity levels and improve the quality of their dietary intake.


Options:
A: Arm Label: Volunteering; Type: EXPERIMENTAL; Interventions: Behavioral: Volunteering | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Volunteering; Assigned to Arm(s): Volunteering
B: Arm Label: COPE/Healthy Lifestyles TEEN Program; Type: EXPERIMENTAL; Interventions: Behavioral: COPE/Healthy Lifestyles TEEN Program. | Arm Label: Healthy Teens Attention Control Program; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Healthy Teens Attention Control Program | Intervention Type: BEHAVIORAL; Name: COPE/Healthy Lifestyles TEEN Program.; Assigned to Arm(s): COPE/Healthy Lifestyles TEEN Program | Intervention Type: BEHAVIORAL; Name: Healthy Teens Attention Control Program; Assigned to Arm(s): Healthy Teens Attention Control Program
C: Arm Label: New Moves Intervention Group; Type: EXPERIMENTAL; Interventions: Behavioral: New Moves | Arm Label: control group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: New Moves; Assigned to Arm(s): New Moves Intervention Group
D: Arm Label: Gardening; Type: EXPERIMENTAL; Interventions: Other: Garden | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Garden; Assigned to Arm(s): Gardening

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Anabolic Steroids and Exercise in Hemodialysis Patients
Brief Summary: This is a study to find out whether an exercise program during dialysis or a drug called nandrolone decanoate can increase muscle size and strenght in patients on dialysis.


Options:
A: Intervention Type: DRUG; Name: nandrolone decanoate; Assigned to Arm(s): N/A | Intervention Type: BEHAVIORAL; Name: resistance exercise training; Assigned to Arm(s): N/A
B: Arm Label: Vadadustat; Type: EXPERIMENTAL; Interventions: Drug: Vadadustat | Arm Label: Darbepoetin alfa; Type: ACTIVE_COMPARATOR; Interventions: Drug: Darbepoetin alfa | Intervention Type: DRUG; Name: Vadadustat; Assigned to Arm(s): Vadadustat | Intervention Type: DRUG; Name: Darbepoetin alfa; Assigned to Arm(s): Darbepoetin alfa
C: Arm Label: HD treated with standard dialysate; Type: ACTIVE_COMPARATOR; Interventions: Device: Standard dialysate (StDi) | Arm Label: post-dilution oHDF with standard dialysate; Type: ACTIVE_COMPARATOR; Interventions: Device: Standard dialysate (StDi) | Arm Label: pre-dilution oHDF with citrate dialysate; Type: EXPERIMENTAL; Interventions: Device: Citrate dialysate (CiDi) | Arm Label: HD treated with citrate dialysate; Type: EXPERIMENTAL; Interventions: Device: Citrate dialysate (CiDi) | Arm Label: post-dilution oHDF with citrate dialysate; Type: EXPERIMENTAL; Interventions: Device: Citrate dialysate (CiDi) | Arm Label: pre-dilution oHDF with standard dialysate; Type: ACTIVE_COMPARATOR; Interventions: Device: Standard dialysate (StDi) | Intervention Type: DEVICE; Name: Citrate dialysate (CiDi); Assigned to Arm(s): HD treated with citrate dialysate, post-dilution oHDF with citrate dialysate, pre-dilution oHDF with citrate dialysate | Intervention Type: DEVICE; Name: Standard dialysate (StDi); Assigned to Arm(s): HD treated with standard dialysate, post-dilution oHDF with standard dialysate, pre-dilution oHDF with standard dialysate
D: Arm Label: Self Management Strategies; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Self-management | Arm Label: Dietary Information; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Dietary Information | Intervention Type: BEHAVIORAL; Name: Self-management; Assigned to Arm(s): Self Management Strategies | Intervention Type: BEHAVIORAL; Name: Dietary Information; Assigned to Arm(s): Dietary Information

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Procalcitonin-Guided Antimicrobial Discontinuation Strategy in Critically Ill Patients With Suspected or Confirmed Bacterial Sepsis
Brief Summary: The current study aims to validate the diagnostic use of PCT assessing its capability to individualize and shorten the duration of antibiotic therapy in critically ill patients with suspected or confirmed sepsis.

In particular, no well-designed intervention study has properly examined the following hypothesis: A PCT-guided antibiotic discontinuation strategy enables to reduce antibiotic treatment duration in critically ill patients with suspected or documented sepsis, without harming patient safety.


Options:
A: Intervention Type: PROCEDURE; Name: PCT measurement; Assigned to Arm(s): N/A
B: Arm Label: 1; Type: EXPERIMENTAL; Interventions: Procedure: Procalcitonin guided strategy | Intervention Type: PROCEDURE; Name: Procalcitonin guided strategy; Assigned to Arm(s): 1
C: Intervention Type: BEHAVIORAL; Name: No antibiotics if se-procalcitonin is below stated limit; Assigned to Arm(s): N/A
D: Arm Label: PCT guided; Type: EXPERIMENTAL; Interventions: Procedure: Earlier therapeutic changes regarding infection | Arm Label: Control; Type: SHAM_COMPARATOR; Interventions: Procedure: Earlier therapeutic changes regarding infection | Intervention Type: PROCEDURE; Name: Earlier therapeutic changes regarding infection; Assigned to Arm(s): Control, PCT guided

Answer: A