Please select the eligibility criteria that correspond to the clinical trial below.
Title: The Effect of Neoadjuvant Chemoradiotherapy on Exercise Capacity in Colrectal Cancer Patients
Brief Summary: Neoadjuvant chemoradiotherapy (NACRT) prior to surgery for lower gastrointestinal (colon and rectal) cancer is associated with improved survival, but also adversely affects physical fitness, potentially rendering patients unfit for major surgery or increasing the risk of adverse outcome (death and serious complications) after major surgery. The investigators aim to obtain pilot data showing that neoadjuvant chemoradiotherapy (NACRT)reduces objectively measured exercise capacity (fitness).


Options:
A: Inclusion Criteria:

* All patients listed to undergo neoadjuvant chemoradiotherapy for downstaging of colorectal cancer, with a view to undergo elective colorectal surgery at Aintree University Hospitals.

Exclusion Criteria:

* Unable to consent.
* Under 18 years of age.
* Significant ischaemic changes of \>1.5mm symptomatic and \> 2mm asymptomatic observed on routine cardiopulmonary exercise test.
* Any other absolute contraindications to CPET based on the ATS guidelines.
B: DISEASE CHARACTERISTICS:

* Survivor of breast, prostate, colon, lung, lymphoma, ovarian, bladder, or esophageal cancer with no evidence of disease
* At least moderate levels of fatigue and/or weakness
* Impaired mobility but ambulatory and medically able to participate in an exercise regimen

  * No impaired knee flexion, defined as \< 90º

PATIENT CHARACTERISTICS:

* Folstein Mini-Mental Status Examination score ≥ 23
* No extreme claustrophobia
* No diagnosed chronic fatigue syndrome/disorder
* No neurological impairments, including the following:

  * Central nervous system disorder (e.g., multiple sclerosis or Parkinson's disease)
  * Neurological insult (cerebrovascular attack) that manifests in a mobility disorder
* No myopathic disease (e.g., focal myopathy) that effects skeletal muscle structure/function
* No rheumatological disease that has an effect on muscle and/or mobility (e.g., polymyalgia rheumatica)

PRIOR CONCURRENT THERAPY:

* More than 6 months since prior regular aerobic or resistance exercise

  * Regular exercise defined as 2-3 times per week
* At least 6 months since prior cancer treatment (surgery, radiation, and/or chemotherapy )
* No concurrent cancer-related treatment other than hormonal therapy
C: Inclusion Criteria:

1. Male and female adult cancer patients 19 years of age or older
2. Patients receiving or planning to receive conventional treatment that includes at least one of chemotherapy, radiotherapy, hormone therapy or active surveillance within 28 days
3. Patients in any stage of cancer diagnoses of all tumour types and locations
4. Participants with internet access and willingness to participate in online communication
5. Participants with access to transportation and personal willingness to attend meetings in central Vancouver, Canada.
6. Participants fluent in the English language

Exclusion Criteria:

1. Patients with any physical limitation, risk of personal injury or under proscription of light to moderate physical activity
2. Patients with pre or post surgical interventions were excluded due to potential physical limitations or safety concerns with wound healing
3. Regular or experienced practitioners of yoga were excluded and defined as those patients reporting current or historical use of regular yoga (\>2 session per month in past 12 months)
4. Patients undergoing medical treatment for serious psychological disturbances that might have interfered with adherence to protocol and/or ability to provide informed consent were excluded (e.g. multiple personality disorders, severe depression, obsessive-compulsive disorder)
D: Inclusion Criteria:

* Newly diagnosed with breast cancer,
* colorectal cancer,
* lymphoma,
* prostate cancer or testicle cancer and scheduled for adjuvant and/or curative treatment in the form of chemotherapy, radiation therapy and/or hormonal therapy at the Department of Oncology and Medical physics, Haukeland University Hospital, (Dept. of Oncology) Bergen,
* residence in Rogaland, Hordaland and Sogn and fjordane county council,
* initial treatment for cancer

Exclusion Criteria:

* An ongoing psychiatric condition,
* language deficiencies in Norwegian,
* surgery for prostate cancer (only applies for prostate cancer) patients),
* men with breast cancer,
* live in nursing homes,
* previous cancer,
* treated for cancer earlier,
* already implemented oncological treatment,
* not self-reliant

Answer: A