Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Phase III Trial Comparing Nicotine Inhaler Versus Bupropion Versus Nicotine Inhaler Plus Bupropion For Smoking Cessation Efficacy And Relapse Prevention
Brief Summary: RATIONALE: Use of a nicotine inhaler and/or bupropion may be effective in helping people stop smoking and prevent them from starting smoking again. It is not yet known whether a nicotine inhaler or bupropion are more effective alone or combined for stopping smoking.

PURPOSE: Randomized phase III trial to compare the effectiveness of the nicotine inhaler or bupropion alone to that of the nicotine inhaler combined with bupropion in helping people to stop smoking and prevent starting smoking again.


Options:
A: Arm Label: Arm I: nicotine inhaler cartridges; Type: EXPERIMENTAL; Interventions: Drug: nicotine | Arm Label: Arm II: bupropion; Type: EXPERIMENTAL; Interventions: Drug: bupropion hydrochloride | Arm Label: Arm III: nicotine inhaler cartridges; Type: EXPERIMENTAL; Interventions: Drug: nicotine | Arm Label: Arm IV: bupropion; Type: EXPERIMENTAL; Interventions: Drug: bupropion hydrochloride | Arm Label: Arm V: placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: placebo | Arm Label: Arm VI: nicotine inhaler cartridges; Type: EXPERIMENTAL; Interventions: Drug: nicotine | Arm Label: Arm VII: placebo inhaler; Type: PLACEBO_COMPARATOR; Interventions: Other: placebo | Arm Label: Arm VIII: nicotine inhaler cartridges; Type: EXPERIMENTAL; Interventions: Drug: nicotine | Arm Label: Arm IX: placebo inhaler cartridges; Type: PLACEBO_COMPARATOR; Interventions: Other: placebo | Arm Label: Arm X: bupropion; Type: EXPERIMENTAL; Interventions: Drug: bupropion hydrochloride | Arm Label: Arm XI: placebo; Type: PLACEBO_COMPARATOR; Interventions: Other: placebo | Arm Label: Arm XII: nicotine inhaler cartridges; Type: EXPERIMENTAL; Interventions: Drug: nicotine | Arm Label: Arm XIII: placebo inhaler cartridges; Type: PLACEBO_COMPARATOR; Interventions: Other: placebo | Arm Label: Arm XIV: nicotine inhaler cartridges; Type: EXPERIMENTAL; Interventions: Drug: nicotine | Arm Label: Arm XV: placebo inhaler cartridges; Type: PLACEBO_COMPARATOR; Interventions: Other: placebo | Intervention Type: OTHER; Name: placebo; Assigned to Arm(s): Arm IX: placebo inhaler cartridges, Arm V: placebo, Arm VII: placebo inhaler, Arm XI: placebo, Arm XIII: placebo inhaler cartridges, Arm XV: placebo inhaler cartridges | Intervention Type: DRUG; Name: bupropion hydrochloride; Assigned to Arm(s): Arm II: bupropion, Arm IV: bupropion, Arm X: bupropion | Intervention Type: DRUG; Name: nicotine; Assigned to Arm(s): Arm I: nicotine inhaler cartridges, Arm III: nicotine inhaler cartridges, Arm VI: nicotine inhaler cartridges, Arm VIII: nicotine inhaler cartridges, Arm XII: nicotine inhaler cartridges, Arm XIV: nicotine inhaler cartridges
B: Arm Label: Extended treatment; Type: EXPERIMENTAL; Interventions: Drug: varenicline, Behavioral: Individual smoking cessation counseling | Arm Label: Standard treatment; Type: ACTIVE_COMPARATOR; Interventions: Drug: varenicline, Behavioral: Individual smoking cessation counseling | Intervention Type: DRUG; Name: varenicline; Assigned to Arm(s): Extended treatment, Standard treatment | Intervention Type: DRUG; Name: varenicline; Assigned to Arm(s): Extended treatment, Standard treatment | Intervention Type: BEHAVIORAL; Name: Individual smoking cessation counseling; Assigned to Arm(s): Extended treatment, Standard treatment
C: Arm Label: Active bupropion-Active gum; Type: ACTIVE_COMPARATOR; Interventions: Drug: bupropion + nicotine gum | Arm Label: Active bupropion-Placebo gum; Type: ACTIVE_COMPARATOR; Interventions: Drug: Active bupropion-Placebo gum | Arm Label: Placebo medication-Placebo gum; Type: ACTIVE_COMPARATOR; Interventions: Drug: Placebo bupropion-Placebo gum | Intervention Type: DRUG; Name: bupropion + nicotine gum; Assigned to Arm(s): Active bupropion-Active gum | Intervention Type: DRUG; Name: Active bupropion-Placebo gum; Assigned to Arm(s): Active bupropion-Placebo gum | Intervention Type: DRUG; Name: Placebo bupropion-Placebo gum; Assigned to Arm(s): Placebo medication-Placebo gum
D: Arm Label: varenicline; Type: ACTIVE_COMPARATOR; Interventions: Drug: varenicline | Arm Label: placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Intervention Type: DRUG; Name: varenicline; Assigned to Arm(s): varenicline | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): placebo

Answer: A