TrialPanorama/Dataset huggingface dataset:
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: SystemCHANGE: An Intervention for Medication Adherence in Transplant Recipients
Brief Summary: With kidney transplant (KT) recipients as our exemplar population, our goal is to develop and test interventions that increase medication adherence (MA) in chronically ill adults. Among adult KT recipients, non-adherence to immunosuppressive medications (MNA) is the leading predictor of poor outcomes, including rejection, kidney loss, and death. An alarming one-third of KT patients experience MNA even though the problem is preventable. Adherence intervention studies have proven marginally effective for those with acute and chronic illnesses and ineffective for adult KT recipients. Using a randomized controlled trial design with an attention-control group, this R01 will test an innovative 6-month SystemCHANGE intervention to enhance immunosuppressive MA in adult non-adherent KT recipients. This intervention shows great promise for increasing MA with a large effect size of 1.4 in our pilot study. Grounded in the socio-ecological model, SystemCHANGE seeks to systematically improve MA behaviors by identifying and shaping routines, involving supportive others in routines, and using medication taking feedback through small patient-lead experiments to change and maintain behavior. The Medication Event Monitoring System cap, which contains microelectronics that record the date and time of the cap removal, will be used to measure MA. Persistence of the MA behavior change will be examined by evaluating the difference in MA between the two groups during the 6-month maintenance phase. Mediators and moderators of MA will be examined. Health outcomes will be compared and a cost-effectiveness analysis will be conducted.


Options:
A: Arm Label: Standard Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: mHealth; Type: EXPERIMENTAL; Interventions: Behavioral: mHealth | Intervention Type: BEHAVIORAL; Name: mHealth; Assigned to Arm(s): mHealth
B: Arm Label: SystemCHANGE; Type: EXPERIMENTAL; Interventions: Behavioral: SystemCHANGE | Arm Label: Patient-education attention-control; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Patient-education attention control | Intervention Type: BEHAVIORAL; Name: SystemCHANGE; Assigned to Arm(s): SystemCHANGE | Intervention Type: BEHAVIORAL; Name: Patient-education attention control; Assigned to Arm(s): Patient-education attention-control
C: Arm Label: Advagraf; Type: EXPERIMENTAL; Interventions: Drug: Advagraf | Arm Label: Prograf; Type: ACTIVE_COMPARATOR; Interventions: Drug: Prograf | Intervention Type: DRUG; Name: Advagraf; Assigned to Arm(s): Advagraf | Intervention Type: DRUG; Name: Prograf; Assigned to Arm(s): Prograf
D: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: behavioral adaptation and symptom management | Arm Label: 2; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: behavioral adaptation and symptom management; Assigned to Arm(s): 1

Answer: B
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Effect of a Hypocaloric Diet With Different Glycemic Indexes on Ghrelin and Leptin Levels, Metabolic Parameters, and Reproductive Outcomes in Overweight and Obese Infertile Women: A Randomized Clinical Trial
Brief Summary: Infertility has been currently recognized as a disorder related to obesity. Among several metabolic changes associated with obesity, insulin resistance appears to be linked to hormonal disorders that affect reproductive system. Leptin and ghrelin are hormones involved in energy balance regulation and are also associated with reproductive system regulation, but its relationship with infertility is scarce. The aim of this study is to determine the effect of a hypocaloric diet with different glycemic indexes on ghrelin and leptin levels, hormonal, metabolic and reproductive parameters in infertile overweight or obese women candidates to in vitro fertilization. The patients who meet the inclusion criteria and accept to participate in the study, will be allocated in one of the following groups: Hypocaloric Low Glycemic Index diet group; Hypocaloric Conventional diet group or Control group (maintenance of usual diet) and follow the study protocol for 12 week. Immediately after the end of the diet protocol, the patients will be submitted to the in vitro fertilization treatment.


Options:
A: Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Behavioral: Placebo | Arm Label: Intensive Dietary Intervention; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Intensive Dietary Intervention | Intervention Type: BEHAVIORAL; Name: Intensive Dietary Intervention; Assigned to Arm(s): Intensive Dietary Intervention | Intervention Type: BEHAVIORAL; Name: Placebo; Assigned to Arm(s): Placebo
B: Arm Label: liraglutide; Type: EXPERIMENTAL; Interventions: Drug: liraglutide | Arm Label: metformin and liraglutide; Type: EXPERIMENTAL; Interventions: Drug: metformin and liraglutide | Intervention Type: DRUG; Name: liraglutide; Assigned to Arm(s): liraglutide | Intervention Type: DRUG; Name: metformin and liraglutide; Assigned to Arm(s): metformin and liraglutide
C: Arm Label: Low Glycemic Index Diet Group; Type: EXPERIMENTAL; Interventions: Other: Low Glycemic Index Diet Group | Arm Label: Conventional Diet Group; Type: ACTIVE_COMPARATOR; Interventions: Other: Conventional Diet Group | Arm Label: Control Group; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Low Glycemic Index Diet Group; Assigned to Arm(s): Low Glycemic Index Diet Group | Intervention Type: OTHER; Name: Conventional Diet Group; Assigned to Arm(s): Conventional Diet Group
D: Intervention Type: DRUG; Name: pioglitazone; Assigned to Arm(s): N/A

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Do You Really Expect Me to Get MST Care in a VA Where Everyone is Male? Innovative Delivery of Evidence Based Psychotherapy to Women With Military Sexual Trauma (MST)
Brief Summary: The purpose of this study is to determine whether a scientifically validated treatment for Posttraumatic Stress Disorder (PTSD) called Prolonged Exposure (PE) can be delivered effectively to Veterans with Military Sexual Trauma (MST) related PTSD using videoconferencing technology, which allows a therapist and patient who are not in the same room as one another to communicate. The investigators are interested in learning if this form of mental health service delivery is an acceptable alternative to traditional face-to-face therapy delivered with the therapist in the same room as the patient. This study is being conducted at the Charleston VA Medical Center and surrounding Community-Based Outpatient Clinics (CBOCs), and will involve approximately 100 female participants.


Options:
A: Arm Label: Arm 1; Type: EXPERIMENTAL; Interventions: Behavioral: Cognitive Processing Therapy | Arm Label: Arm 2; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Present-Centered Therapy | Intervention Type: BEHAVIORAL; Name: Cognitive Processing Therapy; Assigned to Arm(s): Arm 1 | Intervention Type: BEHAVIORAL; Name: Present-Centered Therapy; Assigned to Arm(s): Arm 2
B: Arm Label: Online intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Online intervention | Arm Label: Psycho-educational website; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Psycho-educational website | Intervention Type: BEHAVIORAL; Name: Online intervention; Assigned to Arm(s): Online intervention | Intervention Type: BEHAVIORAL; Name: Psycho-educational website; Assigned to Arm(s): Psycho-educational website
C: Arm Label: STAIR stands for Skills Training in Affective and Interpersonal Regulation; Type: EXPERIMENTAL; Interventions: Behavioral: Skills Training in Affective and Interpersonal Regulation | Arm Label: Present Centered Therapy; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Present Centered Therapy | Intervention Type: BEHAVIORAL; Name: Skills Training in Affective and Interpersonal Regulation; Assigned to Arm(s): STAIR stands for Skills Training in Affective and Interpersonal Regulation | Intervention Type: BEHAVIORAL; Name: Present Centered Therapy; Assigned to Arm(s): Present Centered Therapy
D: Arm Label: PE-HBT; Type: EXPERIMENTAL; Interventions: Behavioral: PE | Arm Label: PE-SD; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: PE | Intervention Type: BEHAVIORAL; Name: PE; Assigned to Arm(s): PE-HBT, PE-SD

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Improving Engagement to HIV Prevention and Care in North West, South Africa
Brief Summary: This study will evaluate the efficacy of two strategies for enhancing overall preventive behaviors, retention in HIV care, and adherence to medication for HIV positive individuals in South Africa: short message service (SMS) text messaging and peer navigation services.


Options:
A: Arm Label: Multilevel Gaming Adherence; Type: EXPERIMENTAL; Interventions: Behavioral: Multilevel Gaming Adherence Intervention | Arm Label: Treatment as Usual +; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Treatment as Usual + | Intervention Type: BEHAVIORAL; Name: Multilevel Gaming Adherence Intervention; Assigned to Arm(s): Multilevel Gaming Adherence | Intervention Type: BEHAVIORAL; Name: Treatment as Usual +; Assigned to Arm(s): Treatment as Usual +
B: Arm Label: Intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Contraceptive instant messages, Other: Mobile phone app | Arm Label: Control; Type: PLACEBO_COMPARATOR; Interventions: Other: Mobile phone app | Intervention Type: BEHAVIORAL; Name: Contraceptive instant messages; Assigned to Arm(s): Intervention | Intervention Type: OTHER; Name: Mobile phone app; Assigned to Arm(s): Control, Intervention
C: Arm Label: Standard of Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: SMS text message; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: SMS text message | Arm Label: SMS text message + Peer Navigation; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: SMS text message + Peer Navigation | Intervention Type: BEHAVIORAL; Name: SMS text message; Assigned to Arm(s): SMS text message | Intervention Type: BEHAVIORAL; Name: SMS text message + Peer Navigation; Assigned to Arm(s): SMS text message + Peer Navigation
D: Arm Label: Smartphone-enabled app for linkage to care; Type: EXPERIMENTAL; Interventions: Other: Smartphone application, Device: Smartphone | Arm Label: Standard of care; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: OTHER; Name: Smartphone application; Assigned to Arm(s): Smartphone-enabled app for linkage to care | Intervention Type: DEVICE; Name: Smartphone; Assigned to Arm(s): Smartphone-enabled app for linkage to care

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Improving Engagement to HIV Prevention and Care in North West, South Africa
Brief Summary: This study will evaluate the efficacy of two strategies for enhancing overall preventive behaviors, retention in HIV care, and adherence to medication for HIV positive individuals in South Africa: short message service (SMS) text messaging and peer navigation services.


Options:
A: Arm Label: Control Arm; Type: ACTIVE_COMPARATOR; Interventions: Other: Standard of Care Treatment | Arm Label: Mobile Health Messaging Arm; Type: EXPERIMENTAL; Interventions: Behavioral: Mobile Health Messaging application, Other: Standard of Care Treatment | Arm Label: Focus Group Arm; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Mobile Health Messaging application; Assigned to Arm(s): Mobile Health Messaging Arm | Intervention Type: OTHER; Name: Standard of Care Treatment; Assigned to Arm(s): Control Arm, Mobile Health Messaging Arm
B: Arm Label: Two-way SMS dialogue; Type: EXPERIMENTAL; Interventions: Behavioral: Two-way SMS Dialogue | Arm Label: One-way SMS Messaging; Type: EXPERIMENTAL; Interventions: Behavioral: One-way SMS Messaging | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Two-way SMS Dialogue; Assigned to Arm(s): Two-way SMS dialogue | Intervention Type: BEHAVIORAL; Name: One-way SMS Messaging; Assigned to Arm(s): One-way SMS Messaging
C: Arm Label: Standard of Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: SMS text message; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: SMS text message | Arm Label: SMS text message + Peer Navigation; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: SMS text message + Peer Navigation | Intervention Type: BEHAVIORAL; Name: SMS text message; Assigned to Arm(s): SMS text message | Intervention Type: BEHAVIORAL; Name: SMS text message + Peer Navigation; Assigned to Arm(s): SMS text message + Peer Navigation
D: Arm Label: SmartMoms-Clinic; Type: EXPERIMENTAL; Interventions: Behavioral: SmartMoms | Arm Label: SmartMoms-Phone; Type: EXPERIMENTAL; Interventions: Behavioral: SmartMoms | Arm Label: Physician Directed; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: SmartMoms; Assigned to Arm(s): SmartMoms-Clinic, SmartMoms-Phone

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Improving Engagement to HIV Prevention and Care in North West, South Africa
Brief Summary: This study will evaluate the efficacy of two strategies for enhancing overall preventive behaviors, retention in HIV care, and adherence to medication for HIV positive individuals in South Africa: short message service (SMS) text messaging and peer navigation services.


Options:
A: Arm Label: Standard of Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: SMS text message; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: SMS text message | Arm Label: SMS text message + Peer Navigation; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: SMS text message + Peer Navigation | Intervention Type: BEHAVIORAL; Name: SMS text message; Assigned to Arm(s): SMS text message | Intervention Type: BEHAVIORAL; Name: SMS text message + Peer Navigation; Assigned to Arm(s): SMS text message + Peer Navigation
B: Arm Label: Controls; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Reminders alone; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Reminders alone | Arm Label: Reminders + compliance-linked incentives; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Reminders alone, Behavioral: Compliance-linked incentives | Intervention Type: BEHAVIORAL; Name: Reminders alone; Assigned to Arm(s): Reminders + compliance-linked incentives, Reminders alone | Intervention Type: BEHAVIORAL; Name: Compliance-linked incentives; Assigned to Arm(s): Reminders + compliance-linked incentives
C: Arm Label: Control, standard care for HPV vaccine; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: Intervention, computer reminder system; Type: EXPERIMENTAL; Interventions: Behavioral: Computer reminder system | Intervention Type: BEHAVIORAL; Name: Computer reminder system; Assigned to Arm(s): Intervention, computer reminder system
D: Arm Label: Motivational SMS; Type: EXPERIMENTAL; Interventions: Behavioral: Motivational SMS | Arm Label: Travel Voucher; Type: EXPERIMENTAL; Interventions: Behavioral: Motivational SMS, Behavioral: Travel Voucher | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Motivational SMS; Assigned to Arm(s): Motivational SMS, Travel Voucher | Intervention Type: BEHAVIORAL; Name: Travel Voucher; Assigned to Arm(s): Travel Voucher

Answer: A
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Improving Engagement to HIV Prevention and Care in North West, South Africa
Brief Summary: This study will evaluate the efficacy of two strategies for enhancing overall preventive behaviors, retention in HIV care, and adherence to medication for HIV positive individuals in South Africa: short message service (SMS) text messaging and peer navigation services.


Options:
A: Arm Label: Connected to Care; Type: EXPERIMENTAL; Interventions: Behavioral: Connected to Care | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: Connected to Care; Assigned to Arm(s): Connected to Care
B: Arm Label: Phone counseling intervention; Type: EXPERIMENTAL; Interventions: Behavioral: Nurse-delivered mobile phone counseling intervention, Behavioral: Treatment as Usual | Arm Label: Treatment as Usual; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: Treatment as Usual | Intervention Type: BEHAVIORAL; Name: Nurse-delivered mobile phone counseling intervention; Assigned to Arm(s): Phone counseling intervention | Intervention Type: BEHAVIORAL; Name: Treatment as Usual; Assigned to Arm(s): Phone counseling intervention, Treatment as Usual
C: Arm Label: Standard of Care; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: SMS text message; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: SMS text message | Arm Label: SMS text message + Peer Navigation; Type: ACTIVE_COMPARATOR; Interventions: Behavioral: SMS text message + Peer Navigation | Intervention Type: BEHAVIORAL; Name: SMS text message; Assigned to Arm(s): SMS text message | Intervention Type: BEHAVIORAL; Name: SMS text message + Peer Navigation; Assigned to Arm(s): SMS text message + Peer Navigation
D: Arm Label: MiQuit; Type: EXPERIMENTAL; Interventions: Behavioral: MiQuit | Arm Label: Control; Type: NO_INTERVENTION; Interventions: N/A | Intervention Type: BEHAVIORAL; Name: MiQuit; Assigned to Arm(s): MiQuit

Answer: C
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: A Japan Post-Marketing, Randomized, Double-Blind, Parallel-Group, Flexible Dose Comparative Study to Assess the Non-Inferiority of Duloxetine Compared With Pregabalin in Patients With Diabetic Peripheral Neuropathic Pain
Brief Summary: The main purpose of this study is to evaluate the effectiveness and safety of the study drug known as duloxetine in participants with diabetic peripheral neuropathic pain.


Options:
A: Arm Label: Sugar pill; Type: PLACEBO_COMPARATOR; Interventions: Drug: Milnacipran | Arm Label: Milnacipran; Type: ACTIVE_COMPARATOR; Interventions: Drug: Milnacipran | Intervention Type: DRUG; Name: Milnacipran; Assigned to Arm(s): Milnacipran, Sugar pill
B: Arm Label: Duloxetine 60 mg; Type: EXPERIMENTAL; Interventions: Drug: Duloxetine 60 mg | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: Duloxetine 60 mg; Assigned to Arm(s): Duloxetine 60 mg | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
C: Arm Label: desvenlafaxine succinate sustained-release (DVS SR) 50mg; Type: EXPERIMENTAL; Interventions: Drug: DVS SR | Arm Label: desvenlafaxine succinate sustained-release (DVS SR) 100mg; Type: EXPERIMENTAL; Interventions: Drug: DVS SR | Arm Label: desvenlafaxine succinate sustained-release (DVS SR) 200mg; Type: EXPERIMENTAL; Interventions: Drug: DVS SR | Arm Label: desvenlafaxine succinate sustained-release (DVS SR) 400mg; Type: EXPERIMENTAL; Interventions: Drug: DVS SR | Arm Label: Placebo; Type: PLACEBO_COMPARATOR; Interventions: Drug: Placebo | Intervention Type: DRUG; Name: DVS SR; Assigned to Arm(s): desvenlafaxine succinate sustained-release (DVS SR) 100mg, desvenlafaxine succinate sustained-release (DVS SR) 200mg, desvenlafaxine succinate sustained-release (DVS SR) 400mg, desvenlafaxine succinate sustained-release (DVS SR) 50mg | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Placebo
D: Arm Label: Duloxetine; Type: EXPERIMENTAL; Interventions: Drug: Duloxetine, Drug: Placebo | Arm Label: Pregabalin; Type: ACTIVE_COMPARATOR; Interventions: Drug: Pregabalin, Drug: Placebo | Intervention Type: DRUG; Name: Duloxetine; Assigned to Arm(s): Duloxetine | Intervention Type: DRUG; Name: Pregabalin; Assigned to Arm(s): Pregabalin | Intervention Type: DRUG; Name: Placebo; Assigned to Arm(s): Duloxetine, Pregabalin

Answer: D
Please select the arm or intervention descriptions that belong to the clinical trial below.
Title: Multimodal Therapeutic Approach by Exercise, Oral Nutritional Supplementation, Omega 3 and Androgen in Undernourished Maintenance Hemodialysis Patients (AMERICANO)
Brief Summary: The aim of the study is to evaluate a 3 months integrated multimodal therapeutic approach including exercise training program with ergocycle during dialysis sessions, oral nutritional supplementation, omega 3 and androgen, on effort tolerance and quality of life of under-nourish maintenance hemodialysis Chronic Kidney Disease (CKD) patient.


Options:
A: Arm Label: Ceprolac; Type: EXPERIMENTAL; Interventions: Dietary Supplement: Ceprolac | Arm Label: Dietary counseling (DC); Type: PLACEBO_COMPARATOR; Interventions: Other: Dietary counseling (DC) | Intervention Type: DIETARY_SUPPLEMENT; Name: Ceprolac; Assigned to Arm(s): Ceprolac | Intervention Type: OTHER; Name: Dietary counseling (DC); Assigned to Arm(s): Dietary counseling (DC)
B: Arm Label: 1; Type: NO_INTERVENTION; Interventions: N/A | Arm Label: 2; Type: ACTIVE_COMPARATOR; Interventions: Drug: nutritional supplementation | Arm Label: 3; Type: ACTIVE_COMPARATOR; Interventions: Drug: nutritional supplementation, Behavioral: exercise | Intervention Type: DRUG; Name: nutritional supplementation; Assigned to Arm(s): 2, 3 | Intervention Type: BEHAVIORAL; Name: exercise; Assigned to Arm(s): 3
C: Arm Label: treated group; Type: EXPERIMENTAL; Interventions: Other: training on ergonomic bicycle, Drug: Testosterone, Drug: Oral nutritional supplementation, Drug: n3 polyunsaturated fatty acid | Arm Label: control group; Type: OTHER; Interventions: Drug: Oral nutritional supplementation | Intervention Type: OTHER; Name: training on ergonomic bicycle; Assigned to Arm(s): treated group | Intervention Type: DRUG; Name: Testosterone; Assigned to Arm(s): treated group | Intervention Type: DRUG; Name: Oral nutritional supplementation; Assigned to Arm(s): control group, treated group | Intervention Type: DRUG; Name: n3 polyunsaturated fatty acid; Assigned to Arm(s): treated group
D: Arm Label: 1; Type: ACTIVE_COMPARATOR; Interventions: Drug: Nepro nutritional supplement | Arm Label: 2; Type: PLACEBO_COMPARATOR; Interventions: Drug: placebo | Intervention Type: DRUG; Name: Nepro nutritional supplement; Assigned to Arm(s): 1 | Intervention Type: DRUG; Name: placebo; Assigned to Arm(s): 2

Answer: C