Please select the eligibility criteria that correspond to the clinical trial below.
Title: Effects of a 5:2 Diet on Weight Loss and Cardiovascular Risk Factors in Obesity
Brief Summary: A randomized clinical trial comparing the effect on weight reduction and cardiometabolic risk factors of intermittent energy restriction and a isocaloric continuous energy restriction in obese subjects.


Options:
A: Inclusion Criteria:

* Female between 18 and 30 years of age
* Current university affiliation
* Weighing at least 110 pounds
* Generally healthy
* Resistance-trained
* Schedule availability to complete supervised resistance training
* Body fat percentage between 15 and 29%

Exclusion Criteria:

* Pregnant or trying to become pregnant
* Currently breastfeeding
* Any disease, condition or orthopedic limitation that would prevent safe participation in resistance training or time-restricted feeding
* Current smoker
* Presence of pacemaker or other electrical implant
* Allergic to dairy proteins
B: Inclusion Criteria:

* Age 20-65 years
* Body mass index (BMI) more than 23.0 kg/m² (overweight or obese for Asian populations, according to the World Health Organization)

Exclusion Criteria:

* Participants with weight gain more than 5kg in the last 3 months
* Participants with history of bariatric surgery
* Participants with secondary obesity, such as hypothyroidism
* Participants with uncontrolled hypertension or type 1 diabetes
* Participants who are taking anti-diabetic medications due to type 2 diabetes
* Participants with hepatic disease (AST or ALT ≥200 mg/dL)
* Participants with renal disease (serum creatinine ≥2.0 mg/dL)
* Participants with pancreatitis or related disorders
* Participants with acute infectious diseases (i.e., pneumonia, acute enteritis, or urinary infection)
* Participants with chronic inflammatory diseases (i.e., rheumatoid arthritis, or lupus)
* Participants with overeating behavior
* Participants with history of cardiovascular diseases
* Participants with history of cancer
* Participants who are taking anti-obesity, anti-diabetic, diuretic, central-nervous system, antidepressant, antipsychotic, or steroid medications
* Pregnant or lactating women
* Participants who intake more than 30 g of alcohol daily
* Night-time or shift-work workers
* Participants with chronic malabsorption syndrome or cholestasis
* Participants with other medical conditions that would preclude subjects from participating in exercise and physical test
C: Inclusion Criteria:

* Men and women between 21 to 70 years.
* BMI (BMI 30-45 kg/m2).
* stable weight within ±3 kg last 3 months.
* 1 additional metabolic syndrome risk component.

Exclusion Criteria:

* Diabetes if treated with insulin or incretin analogues.
* History of bariatric surgery.
* Use of antiobesity drugs or supplements.
* Eating disorder.
* Psychiatric illness that contributes to difficulties with study procedures.
* Alcohol or drug abuse.
D: Inclusion Criteria:

* Age between 18 to 65 years old
* BMI between 30.0 and 49.9 kg/m2
* Previously sedentary or lightly active

Exclusion Criteria:

* Diabetic
* History of binge eating disorder
* Taking weight loss-inducing medications
* Not weight stable for 3 months prior to the study (weight gain or loss \> 4 kg)
* Perimenopausal or have an irregular menstrual cycle (menses that does not appear every 27-32 days)
* Pregnant or trying to become pregnant
* Night shift worker
* Smokers

Answer: C