You are given a scientific article and a question. Answer the question as concisely as you can, using a single phrase or sentence if possible. If the question cannot be answered based on the information in the article, write "unanswerable". If the question is a yes/no question, answer "yes", "no", or "unanswerable". Do not provide any explanation.

Introduction
In recent years, there has been a movement to leverage social medial data to detect, estimate, and track the change in prevalence of disease. For example, eating disorders in Spanish language Twitter tweets BIBREF0 and influenza surveillance BIBREF1 . More recently, social media has been leveraged to monitor social risks such as prescription drug and smoking behaviors BIBREF2 , BIBREF3 , BIBREF4 as well as a variety of mental health disorders including suicidal ideation BIBREF5 , attention deficient hyperactivity disorder BIBREF6 and major depressive disorder BIBREF7 . In the case of major depressive disorder, recent efforts range from characterizing linguistic phenomena associated with depression BIBREF8 and its subtypes e.g., postpartum depression BIBREF5 , to identifying specific depressive symptoms BIBREF9 , BIBREF10 e.g., depressed mood. However, more research is needed to better understand the predictive power of supervised machine learning classifiers and the influence of feature groups and feature sets for efficiently classifying depression-related tweets to support mental health monitoring at the population-level BIBREF11 .
This paper builds upon related works toward classifying Twitter tweets representing symptoms of major depressive disorder by assessing the contribution of lexical features (e.g., unigrams) and emotion (e.g., strongly negative) to classification performance, and by applying methods to eliminate low-value features.
METHODS
Specifically, we conducted a feature ablation study to assess the informativeness of each feature group and a feature elimination study to determine the optimal feature sets for classifying Twitter tweets. We leveraged an existing, annotated Twitter dataset that was constructed based on a hierarchical model of depression-related symptoms BIBREF12 , BIBREF13 . The dataset contains 9,473 annotations for 9,300 tweets. Each tweet is annotated as no evidence of depression (e.g., “Citizens fear an economic depression") or evidence of depression (e.g., “depressed over disappointment"). If a tweet is annotated evidence of depression, then it is further annotated with one or more depressive symptoms, for example, depressed mood (e.g., “feeling down in the dumps"), disturbed sleep (e.g., “another restless night"), or fatigue or loss of energy (e.g., “the fatigue is unbearable") BIBREF10 . For each class, every annotation (9,473 tweets) is binarized as the positive class e.g., depressed mood=1 or negative class e.g., not depressed mood=0.
Features
Furthermore, this dataset was encoded with 7 feature groups with associated feature values binarized (i.e., present=1 or absent=0) to represent potentially informative features for classifying depression-related classes. We describe the feature groups by type, subtype, and provide one or more examples of words representing the feature subtype from a tweet:
lexical features, unigrams, e.g., “depressed”;
syntactic features, parts of speech, e.g., “cried” encoded as V for verb;
emotion features, emoticons, e.g., :( encoded as SAD;
demographic features, age and gender e.g., “this semester” encoded as an indicator of 19-22 years of age and “my girlfriend” encoded as an indicator of male gender, respectively;
sentiment features, polarity and subjectivity terms with strengths, e.g., “terrible” encoded as strongly negative and strongly subjective;
personality traits, neuroticism e.g., “pissed off” implies neuroticism;
LIWC Features, indicators of an individual's thoughts, feelings, personality, and motivations, e.g., “feeling” suggestions perception, feeling, insight, and cognitive mechanisms experienced by the Twitter user.
A more detailed description of leveraged features and their values, including LIWC categories, can be found in BIBREF10 .
Based on our prior initial experiments using these feature groups BIBREF10 , we learned that support vector machines perform with the highest F1-score compared to other supervised approaches. For this study, we aim to build upon this work by conducting two experiments: 1) to assess the contribution of each feature group and 2) to determine the optimal percentile of top ranked features for classifying Twitter tweets in the depression schema hierarchy.
Feature Contribution
Feature ablation studies are conducted to assess the informativeness of a feature group by quantifying the change in predictive power when comparing the performance of a classifier trained with the all feature groups versus the performance without a particular feature group. We conducted a feature ablation study by holding out (sans) each feature group and training and testing the support vector model using a linear kernel and 5-fold, stratified cross-validation. We report the average F1-score from our baseline approach (all feature groups) and report the point difference (+ or -) in F1-score performance observed by ablating each feature set.
By ablating each feature group from the full dataset, we observed the following count of features - sans lexical: 185, sans syntactic: 16,935, sans emotion: 16,954, sans demographics: 16,946, sans sentiment: 16,950, sans personality: 16,946, and sans LIWC: 16,832. In Figure 1, compared to the baseline performance, significant drops in F1-scores resulted from sans lexical for depressed mood (-35 points), disturbed sleep (-43 points), and depressive symptoms (-45 points). Less extensive drops also occurred for evidence of depression (-14 points) and fatigue or loss of energy (-3 points). In contrast, a 3 point gain in F1-score was observed for no evidence of depression. We also observed notable drops in F1-scores for disturbed sleep by ablating demographics (-7 points), emotion (-5 points), and sentiment (-5 points) features. These F1-score drops were accompanied by drops in both recall and precision. We found equal or higher F1-scores by removing non-lexical feature groups for no evidence of depression (0-1 points), evidence of depression (0-1 points), and depressive symptoms (2 points).
Unsurprisingly, lexical features (unigrams) were the largest contributor to feature counts in the dataset. We observed that lexical features are also critical for identifying depressive symptoms, specifically for depressed mood and for disturbed sleep. For the classes higher in the hierarchy - no evidence of depression, evidence of depression, and depressive symptoms - the classifier produced consistent F1-scores, even slightly above the baseline for depressive symptoms and minor fluctuations of change in recall and precision when removing other feature groups suggesting that the contribution of non-lexical features to classification performance was limited. However, notable changes in F1-score were observed for the classes lower in the hierarchy including disturbed sleep and fatigue or loss of energy. For instance, changes in F1-scores driven by both recall and precision were observed for disturbed sleep by ablating demographics, emotion, and sentiment features, suggesting that age or gender (“mid-semester exams have me restless”), polarity and subjective terms (“lack of sleep is killing me”), and emoticons (“wide awake :(”) could be important for both identifying and correctly classifying a subset of these tweets.
Feature Elimination
Feature elimination strategies are often taken 1) to remove irrelevant or noisy features, 2) to improve classifier performance, and 3) to reduce training and run times. We conducted an experiment to determine whether we could maintain or improve classifier performances by applying the following three-tiered feature elimination approach:
Reduction We reduced the dataset encoded for each class by eliminating features that occur less than twice in the full dataset.
Selection We iteratively applied Chi-Square feature selection on the reduced dataset, selecting the top percentile of highest ranked features in increments of 5 percent to train and test the support vector model using a linear kernel and 5-fold, stratified cross-validation.
Rank We cumulatively plotted the average F1-score performances of each incrementally added percentile of top ranked features. We report the percentile and count of features resulting in the first occurrence of the highest average F1-score for each class.
All experiments were programmed using scikit-learn 0.18.
The initial matrices of almost 17,000 features were reduced by eliminating features that only occurred once in the full dataset, resulting in 5,761 features. We applied Chi-Square feature selection and plotted the top-ranked subset of features for each percentile (at 5 percent intervals cumulatively added) and evaluated their predictive contribution using the support vector machine with linear kernel and stratified, 5-fold cross validation.
In Figure 2, we observed optimal F1-score performance using the following top feature counts: no evidence of depression: F1: 87 (15th percentile, 864 features), evidence of depression: F1: 59 (30th percentile, 1,728 features), depressive symptoms: F1: 55 (15th percentile, 864 features), depressed mood: F1: 39 (55th percentile, 3,168 features), disturbed sleep: F1: 46 (10th percentile, 576 features), and fatigue or loss of energy: F1: 72 (5th percentile, 288 features) (Figure 1). We note F1-score improvements for depressed mood from F1: 13 at the 1st percentile to F1: 33 at the 20th percentile.
We observed peak F1-score performances at low percentiles for fatigue or loss of energy (5th percentile), disturbed sleep (10th percentile) as well as depressive symptoms and no evidence of depression (both 15th percentile) suggesting fewer features are needed to reach optimal performance. In contrast, peak F1-score performances occurred at moderate percentiles for evidence of depression (30th percentile) and depressed mood (55th percentile) suggesting that more features are needed to reach optimal performance. However, one notable difference between these two classes is the dramatic F1-score improvements for depressed mood i.e., 20 point increase from the 1st percentile to the 20th percentile compared to the more gradual F1-score improvements for evidence of depression i.e., 11 point increase from the 1st percentile to the 20th percentile. This finding suggests that for identifying depressed mood a variety of features are needed before incremental gains are observed.
RESULTS
From our annotated dataset of Twitter tweets (n=9,300 tweets), we conducted two feature studies to better understand the predictive power of several feature groups for classifying whether or not a tweet contains no evidence of depression (n=6,829 tweets) or evidence of depression (n=2,644 tweets). If there was evidence of depression, we determined whether the tweet contained one or more depressive symptoms (n=1,656 tweets) and further classified the symptom subtype of depressed mood (n=1,010 tweets), disturbed sleep (n=98 tweets), or fatigue or loss of energy (n=427 tweets) using support vector machines. From our prior work BIBREF10 and in Figure 1, we report the performance for prediction models built by training a support vector machine using 5-fold, stratified cross-validation with all feature groups as a baseline for each class. We observed high performance for no evidence of depression and fatigue or loss of energy and moderate performance for all remaining classes.
Discussion
We conducted two feature study experiments: 1) a feature ablation study to assess the contribution of feature groups and 2) a feature elimination study to determine the optimal percentile of top ranked features for classifying Twitter tweets in the depression schema hierarchy.
Future Work
Our next step is to address the classification of rarer depressive symptoms suggestive of major depressive disorder from our dataset and hierarchy including inappropriate guilt, difficulty concentrating, psychomotor agitation or retardation, weight loss or gain, and anhedonia BIBREF15 , BIBREF16 . We are developing a population-level monitoring framework designed to estimate the prevalence of depression (and depression-related symptoms and psycho-social stressors) over millions of United States-geocoded tweets. Identifying the most discriminating feature sets and natural language processing classifiers for each depression symptom is vital for this goal.
Conclusions
In summary, we conducted two feature study experiments to assess the contribution of feature groups and to determine the optimal percentile of top ranked features for classifying Twitter tweets in the depression schema hierarchy. From these experiments, we conclude that simple lexical features and reduced feature sets can produce comparable results to the much larger feature dataset.
Acknowledgments
Research reported in this publication was supported by the National Library of Medicine of the [United States] National Institutes of Health under award numbers K99LM011393 and R00LM011393. This study was granted an exemption from review by the University of Utah Institutional Review Board (IRB 00076188). Note that in order to protect tweeter anonymity, we have not reproduced tweets verbatim. Example tweets shown were generated by the researchers as exemplars only. Finally, we would like to thank the anonymous reviewers of this paper for their valuable comments.
Please answer the question based on the text provided above. How is the dataset annotated?

Answer: no evidence of depression, depressed mood, disturbed sleep, fatigue or loss of energy The annotations are based on evidence of depression and further annotated by the depressive symptom if there is evidence of depression