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Question: What are the three synthetic types of vitamin K?

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Context 1: Vitamin K - Wikipedia
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This article needs more medical references for verification or relies too heavily on primary sources  Please review the contents of the article and add the appropriate references if you can  Unsourced or poorly sourced material may be challenged and removed  (November 2015)
This article is about the family of vitamers  For vitamin K1 the form usually used as a supplement, see Phytomenadione 
Vitamin K structures  MK-4 and MK-7 are both subtypes of K2 
Vitamin K deficiency, Warfarin overdose
Vitamin K is a group of structurally similar, fat-soluble vitamins the human body requires for complete synthesis of certain proteins that are prerequisites for blood coagulation and which the body also needs for controlling binding of calcium in bones and other tissues  The vitamin K-related modification of the proteins allows them to bind calcium ions, which they cannot do otherwise  Without vitamin K, blood coagulation is seriously impaired, and uncontrolled bleeding occurs  Low levels of vitamin K also weaken bones and promote calcification of arteries and other soft tissues[citation needed] 
Chemically, the vitamin K family comprises 2-methyl-1,4-naphthoquinone (3-) derivatives  Vitamin K includes two natural vitamers: vitamin K1 and vitamin K2 [1] Vitamin K2, in turn, consists of a number of related chemical subtypes, with differing lengths of carbon side chains made of isoprenoid groups of atoms 
Vitamin K1, also known as phylloquinone, is made by plants, and is found in highest amounts in green leafy vegetables because it is directly involved in photosynthesis  It may be thought of as the plant form of vitamin K  It is active as a vitamin in animals and performs the classic functions of vitamin K, including its activity in the production of blood-clotting proteins  Animals may also convert it to vitamin K2 
Bacteria in the gut flora can also convert K1 into vitamin K2  In addition, bacteria typically lengthen the isoprenoid side chain of vitamin K2 to produce a range of vitamin K2 forms, most notably the MK-7 to MK-11 homologues of vitamin K2  All forms of K2 other than MK-4 can only be produced by bacteria, which use these forms in anaerobic respiration  The MK-7 and other bacterially derived forms of vitamin K2 exhibit vitamin K activity in animals, but MK-7's extra utility over MK-4, if any, is unclear and is a matter of investigation 
Three synthetic types of vitamin K are known: vitamins K3, K4, and K5  Although the natural K1 and all K2 homologues and synthetic K4 and K5 have proven nontoxic, the synthetic form K3 (menadione) has shown toxicity [2]
1 2 Cardiovascular health
1 4 Coumarin poisoning
4 1 Conversion of vitamin K1 to vitamin K2
4 2 Vitamin K2
6 Absorption and dietary need
7 Dietary reference intake
10 Biochemistry
10 1 Function in animals
10 2 Gamma-carboxyglutamate proteins
10 3 Methods of assessment
10 4 Function in bacteria
11 Injection in newborns
11 3 Controversy
A review of 2014 concluded that there is positive evidence that monotherapy using MK-4, one of the forms of Vitamin K2, reduces fracture incidence in post-menopausal women with osteoporosis, and suggested further research on the combined use of MK-4 with bisphosphonates  In contrast, an earlier review article of 2013 concluded that there is no good evidence that vitamin K supplementation helps prevent osteoporosis or fractures in postmenopausal women [3]
A Cochrane systematic review of 2006 suggested that supplementation with Vitamin K1 and with MK4 reduces bone loss; in particular, a strong effect of MK-4 on incident fractures among Japanese patients was emphasized [4]
A review article of 2016 suggested to consider, as one of several measures for bone health, increasing the intake of foods rich in vitamins K1 and K2 [5]
Cardiovascular health[edit]
Adequate intake of vitamin K is associated with the inhibition of arterial calcification and stiffening,[6] but there have been few interventional studies and no good evidence that vitamin K supplementation is of any benefit in the primary prevention of cardiovascular disease [7]
One 10-year population study, the Rotterdam Study, did show a clear and significant inverse relationship between the highest intake levels of menaquinone (mainly MK-4 from eggs and meat, and MK-8 and MK-9 from cheese) and cardiovascular disease and all-cause mortality in older men and women [8]
Vitamin K has been promoted in supplement form with claims it can slow tumor growth; there is however no good medical evidence that supports such claims [9]
Coumarin poisoning[edit]
Vitamin K is part of the suggested treatment regime for poisoning by rodenticide (coumarin poisoning) [10]
Although allergic reaction from supplementation is possible, no known toxicity is associated with high doses of the phylloquinone (vitamin K1) or menaquinone (vitamin K2) forms of vitamin K, so no tolerable upper intake level (UL) has been set [11]
Blood clotting (coagulation) studies in humans using 45 mg per day of vitamin K2 (as MK-4)[12] and even up to 135 mg per day (45 mg three times daily) of K2 (as MK-4),[13] showed no increase in blood clot risk  Even doses in rats as high as 250 mg/kg, body weight did not alter the tendency for blood-clot formation to occur [14]
Unlike the safe natural forms of vitamin K1 and vitamin K2 and their various isomers, a synthetic form of vitamin K, vitamin K3 (menadione), is demonstrably toxic at high levels  The U S  FDA has banned this form from over-the-counter sale in the United States because large doses have been shown to cause allergic reactions, hemolytic anemia, and cytotoxicity in liver cells [2]
Phylloquinone (K1)[15][16] or menaquinone (K2) are capable of reversing the anticoagulant activity of the anticoagulant warfarin (tradename Coumadin)  Warfarin works by blocking recycling of vitamin K, so that the body and tissues have lower levels of active vitamin K, and thus a deficiency of vitamin K 
Supplemental vitamin K (for which oral dosing is often more active than injectable dosing in human adults) reverses the vitamin K deficiency caused by warfarin, and therefore reduces the intended anticoagulant action of warfarin and related drugs [17] Sometimes small amounts of vitamin K are given orally to patients taking warfarin so that the action of the drug is more predictable [17] The proper anticoagulant action of the drug is a function of vitamin K intake and drug dose, and due to differing absorption must be individualized for each patient [citation needed] The action of warfarin and vitamin K both require two to five days after dosing to have maximum effect, and neither warfarin or vitamin K shows much effect in the first 24 hours after they are given [18]
The newer anticoagulants dabigatran and rivaroxaban have different mechanisms of action that do not interact with vitamin K, and may be taken with supplemental vitamin K [19][20]
Vitamin K2 (menaquinone)  In menaquinone, the side chain is composed of a varying number of isoprenoid residues  The most common number of these residues is four, since animal enzymes normally produce menaquinone-4 from plant phylloquinone 
A sample of phytomenadione for injection, also called phylloquinone
The three synthetic forms of vitamin K are vitamins K3 (menadione), K4, and K5, which are used in many areas, including the pet food industry (vitamin K3) and to inhibit fungal growth (vitamin K5) [21]
Conversion of vitamin K1 to vitamin K2[edit]
Vitamin K1 (phylloquinone) – both forms of the vitamin contain a functional naphthoquinone ring and an aliphatic side chain  Phylloquinone has a phytyl side chain 
The MK-4 form of vitamin K2 is produced by conversion of vitamin K1 in the testes, pancreas, and arterial walls [22] While major questions still surround the biochemical pathway for this transformation, the conversion is not dependent on gut bacteria, as it occurs in germ-free rats[23][24] and in parenterally-administered K1 in rats [25][26] In fact, tissues that accumulate high amounts of MK-4 have a remarkable capacity to convert up to 90% of the available K1 into MK-4 [27][28] There is evidence that the conversion proceeds by removal of the phytyl tail of K1 to produce menadione as an intermediate, which is then condensed with an activated geranylgeranyl moiety (see also prenylation) to produce vitamin K2 in the MK-4 (menatetrione) form [29]
Vitamin K2[edit]
Main article: Vitamin K2
Vitamin K2 (menaquinone) includes several subtypes  The two subtypes most studied are menaquinone-4 (menatetrenone, MK-4) and menaquinone-7 (MK-7) 
Vitamin K1, the precursor of most vitamin K in nature, is a stereoisomer of phylloquinone, an important chemical in green plants, where it functions as an electron acceptor in photosystem I during photosynthesis  For this reason, vitamin K1 is found in large quantities in the photosynthetic tissues of plants (green leaves, and dark green leafy vegetables such as romaine lettuce, kale and spinach), but it occurs in far smaller quantities in other plant tissues (roots, fruits, etc )  Iceberg lettuce contains relatively little  The function of phylloquinone in plants appears to have no resemblance to its later metabolic and biochemical function (as "vitamin K") in animals, where it performs a completely different biochemical reaction 
Vitamin K (in animals) is involved in the carboxylation of certain glutamate residues in proteins to form gamma-carboxyglutamate (Gla) residues  The modified residues are often (but not always) situated within specific protein domains called Gla domains  Gla residues are usually involved in binding calcium, and are essential for the biological activity of all known Gla proteins [30]
At this time[update], 17 human proteins with Gla domains have been discovered, and they play key roles in the regulation of three physiological processes:
Blood coagulation: prothrombin (factor II), factors VII, IX, and X, and proteins C, S, and Z[31]
Bone metabolism: osteocalcin, also called bone Gla protein (BGP), matrix Gla protein (MGP),[32] periostin,[33] and the recently discovered Gla-rich protein (GRP) [34][35]
Vascular biology: growth arrest-specific protein 6 (Gas6)[36]
Unknown function: proline-rich γ-carboxyglutamyl proteins (PRGPs) 1 and 2, and transmembrane γ-carboxy glutamyl proteins (TMGs) 3 and 4 [37]
Like other lipid-soluble vitamins (A, D and E), vitamin K is stored in the fatty tissue of the human body 
Absorption and dietary need[edit]
Previous theory held that dietary deficiency is extremely rare unless the small intestine was heavily damaged, resulting in malabsorption of the molecule  Another at-risk group for deficiency were those subject to decreased production of K2 by normal intestinal microbiota, as seen in broad spectrum antibiotic use [38] Taking broad-spectrum antibiotics can reduce vitamin K production in the gut by nearly 74% in people compared with those not taking these antibiotics [39] Diets low in vitamin K also decrease the body's vitamin K concentration [40] Those with chronic kidney disease are at risk for vitamin K deficiency, as well as vitamin D deficiency, and particularly those with the apoE4 genotype [41] Additionally, in the elderly there is a reduction in vitamin K2 production [42]
The National Academy of Medicine (NAM) updated an estimate of what constitutes an adequate intake (AI) for vitamin K in 2001  The NAM does not distinguish between K1 and K2 – both are counted as vitamin K  At that time there was not sufficient evidence to set the more rigorous estimated average requirement (EAR) or recommended dietary allowance (RDA) given for most of the essential vitamins and minerals  The current daily AIs for vitamin K for adult women and men are 90 μg and 120 μg respectively  The AI for pregnancy and lactation is 90 μg  For infants up to 12 months the AI is 2–2 5 μg, and for children aged 1 to 18 years the AI increases with age from 30 to 75 μg  As for safety, the FNB also sets tolerable upper intake levels (known as ULs) for vitamins and minerals when evidence is sufficient  In the case of vitamin K no UL is set, as evidence for adverse effects is not sufficient  Collectively EARs, RDAs, AIs and ULs are referred to as dietary reference intakes [43] The European Food Safety Authority reviewed the same safety question and did not set an UL [44]
For U S  food and dietary supplement labeling purposes, the amount in a serving is expressed as a percentage of daily value (%DV)  For vitamin K labeling purposes the daily value was 80 μg, but as of May 2016 it has been revised upwards to 120 μg  A table of the pre-change adult daily values is provided at reference daily intake  Food and supplement companies have until 28 July 2018 to comply with the change 
See also: Vitamin K2 § Dietary sources
K1 (μg)[45]
Kale, cooked
Collards, cooked
Collards, raw
Swiss chard, cooked
Swiss chard, raw
Turnip greens, raw
Romaine lettuce, raw
Table from "Important information to know when you are taking: Warfarin (Coumadin) and Vitamin K", Clinical Center, National Institutes of Health Drug Nutrient Interaction Task Force [46]
Vitamin K1 is found chiefly in leafy green vegetables such as dandelion greens (which contain 778 4 μg per 100 g, or 741% of the recommended daily amount), spinach, swiss chard, lettuce and Brassica vegetables (such as cabbage, kale, cauliflower, broccoli, and brussels sprouts) and often the absorption is greater when accompanied by fats such as butter or oils; some fruits, such as avocados, kiwifruit and grapes, are also high in vitamin K  By way of reference, two tablespoons of parsley contains 153% of the recommended daily amount of vitamin K [47] Some vegetable oils, notably soybean oil, contain vitamin K, but at levels that would require relatively large calorie consumption to meet the USDA-recommended levels [48] colonic bacteria synthesize a significant portion of humans' vitamin K needs; newborns often receive a vitamin K shot at birth to tide them over until their colons become colonized at five to seven days of age from the consumption of breast milk 
The tight binding of vitamin K1 to thylakoid membranes in chloroplasts makes it less bioavailable  For example, cooked spinach has a 5% bioavailability of phylloquinone, however, fat added to it increases bioavailability to 13% due to the increased solubility of vitamin K in fat [49]
Main article: Vitamin K deficiency
Average diets are usually not lacking in vitamin K, and primary deficiency is rare in healthy adults  Newborn infants are at an increased risk of deficiency  Other populations with an increased prevalence of vitamin K deficiency include those who suffer from liver damage or disease (e g  alcoholics), cystic fibrosis, or inflammatory bowel diseases, or have recently had abdominal surgeries  Secondary vitamin K deficiency can occur in people with bulimia, those on stringent diets, and those taking anticoagulants  Other drugs associated with vitamin K deficiency include salicylates, barbiturates, and cefamandole, although the mechanisms are still unknown  Vitamin K1 deficiency can result in coagulopathy, a bleeding disorder [50]Symptoms of K1 deficiency include anemia, bruising, nosebleeds and bleeding of the gums in both sexes, and heavy menstrual bleeding in women 
Osteoporosis[51][52] and coronary heart disease[53][54] are strongly associated with lower levels of K2 (menaquinone)  Vitamin K2 (as menaquinones MK-4 through MK-10) intake level is inversely related to severe aortic calcification and all-cause mortality [8]
Function in animals[edit]
Mechanism of action of vitamin K1 
The function of vitamin K2 in the animal cell is to add a carboxylic acid functional group to a glutamate (Glu) amino acid residue in a protein, to form a gamma-carboxyglutamate (Gla) residue  This is a somewhat uncommon posttranslational modification of the protein, which is then known as a "Gla protein"  The presence of two −COOH (carboxylic acid) groups on the same carbon in the gamma-carboxyglutamate residue allows it to chelate calcium ions  The binding of calcium ions in this way very often triggers the function or binding of Gla-protein enzymes, such as the so-called vitamin K-dependent clotting factors discussed below 
Within the cell, vitamin K undergoes electron reduction to a reduced form called vitamin K hydroquinone, catalyzed by the enzyme vitamin K epoxide reductase (VKOR) [55] Another enzyme then oxidizes vitamin K hydroquinone to allow carboxylation of Glu to Gla; this enzyme is called gamma-glutamyl carboxylase[56][57] or the vitamin K-dependent carboxylase  The carboxylation reaction only proceeds if the carboxylase enzyme is able to oxidize vitamin K hydroquinone to vitamin K epoxide at the same time  The carboxylation and epoxidation reactions are said to be coupled  Vitamin K epoxide is then reconverted to vitamin K by VKOR  The reduction and subsequent reoxidation of vitamin K coupled with carboxylation of Glu is called the vitamin K cycle [58] Humans are rarely deficient in vitamin K1 because, in part, vitamin K1 is continuously recycled in cells [59]
Warfarin and other 4-hydroxycoumarins block the action of VKOR [60] This results in decreased concentrations of vitamin K and vitamin K hydroquinone in tissues, such that the carboxylation reaction catalyzed by the glutamyl carboxylase is inefficient  This results in the production of clotting factors with inadequate Gla  Without Gla on the amino termini of these factors, they no longer bind stably to the blood vessel endothelium and cannot activate clotting to allow formation of a clot during tissue injury  As it is impossible to predict what dose of warfarin will give the desired degree of clotting suppression, warfarin treatment must be carefully monitored to avoid overdose 
Gamma-carboxyglutamate proteins[edit]
Main article: Gla domain
The following human Gla-containing proteins ("Gla proteins") have been characterized to the level of primary structure: blood coagulation factors II (prothrombin), VII, IX, and X, anticoagulant proteins C and S, and the factor X-targeting protein Z  The bone Gla protein osteocalcin, the calcification-inhibiting matrix Gla protein (MGP), the cell growth regulating growth arrest specific gene 6 protein (Gas6), and the four transmembrane Gla proteins (TMGPs), the function of which is at present unknown  Gas6 can function as a growth factor to activate the Axl receptor tyrosine kinase and stimulate cell proliferation or prevent apoptosis in some cells  In all cases in which their function was known, the presence of the Gla residues in these proteins turned out to be essential for functional activity 
Gla proteins are known to occur in a wide variety of vertebrates: mammals, birds, reptiles, and fish  The venom of a number of Australian snakes acts by activating the human blood-clotting system  In some cases, activation is accomplished by snake Gla-containing enzymes that bind to the endothelium of human blood vessels and catalyze the conversion of procoagulant clotting factors into activated ones, leading to unwanted and potentially deadly clotting 
Another interesting class of invertebrate Gla-containing proteins is synthesized by the fish-hunting snail Conus geographus [61] These snails produce a venom containing hundreds of neuroactive peptides, or conotoxins, which is sufficiently toxic to kill an adult human  Several of the conotoxins contain two to five Gla residues [62]
Methods of assessment[edit]
Vitamin K status can be assessed by:
The prothrombin time (PT) test measures the time required for blood to clot  A blood sample is mixed with citric acid and put in a fibrometer; delayed clot formation indicates a deficiency  This test is insensitive to mild deficiency, as the values do not change until the concentration of prothrombin in the blood has declined by at least 50% [63]
Undercarboxylated prothrombin (PIVKA-II); in a study of 53 newborns, found "PT (prothrombin time) is a less sensitive marker than PIVKA II",[64] and as indicated above, PT is unable to detect subclinical deficiencies that can be detected with PIVKA-II testing 
Plasma phylloquinone was found to be positively correlated with phylloquinone intake in elderly British women, but not men,[65] but an article by Schurgers et al  reported no correlation between FFQ[further explanation needed] and plasma phylloquinone [66]
Urinary γ-carboxyglutamic acid responds to changes in dietary vitamin K intake  Several days are required before any change can be observed  In a study by Booth et al , increases of phylloquinone intakes from 100 μg to between 377 and 417 μg for five days did not induce a significant change  Response may be age-specific [67]
Undercarboxylated osteocalcin (UcOc) levels have been inversely correlated with stores of vitamin K[68] and bone strength in developing rat tibiae  Another study following 78 post-menopausal Korean women found a supplement regimen of vitamins K and D, and calcium, but not a regimen of vitamin D and calcium, was inversely correlated with reduced UcOc levels [69]
Function in bacteria[edit]
Many bacteria, such as Escherichia coli found in the large intestine, can synthesize vitamin K2 (menaquinone-7 or MK-7, up to MK-11),[70] but not vitamin K1 (phylloquinone)  In these bacteria, menaquinone transfers two electrons between two different small molecules, during oxygen-independent metabolic energy production processes (anaerobic respiration) [71] For example, a small molecule with an excess of electrons (also called an electron donor) such as lactate, formate, or NADH, with the help of an enzyme, passes two electrons to menaquinone  The menaquinone, with the help of another enzyme, then transfers these two electrons to a suitable oxidant, such fumarate or nitrate (also called an electron acceptor)  Adding two electrons to fumarate or nitrate converts the molecule to succinate or nitrite plus water, respectively 
Some of these reactions generate a cellular energy source, ATP, in a manner similar to eukaryotic cell aerobic respiration, except the final electron acceptor is not molecular oxygen, but fumarate or nitrate  In aerobic respiration, the final oxidant is molecular oxygen (O2), which accepts four electrons from an electron donor such as NADH to be converted to water  E  coli, as facultative anaerobes, can carry out both aerobic respiration and menaquinone-mediated anaerobic respiration 
Injection in newborns[edit]
The blood clotting factors of newborn babies are roughly 30–60% that of adult values; this may be due to the reduced synthesis of precursor proteins and the sterility of their guts  Human milk contains 1–4 μg/L of vitamin K1, while formula-derived milk can contain up to 100 μg/L in supplemented formulas  Vitamin K2 concentrations in human milk appear to be much lower than those of vitamin K1  Occurrence of vitamin K deficiency bleeding in the first week of the infant's life is estimated at 0 25–1 7%, with a prevalence of 2–10 cases per 100,000 births [72] Premature babies have even lower levels of the vitamin, so they are at a higher risk from this deficiency 
Bleeding in infants due to vitamin K deficiency can be severe, leading to hospitalization, blood transfusions, brain damage, and death  Supplementation can prevent most cases of vitamin K deficiency bleeding in the newborn  Intramuscular administration is more effective in preventing late vitamin K deficiency bleeding than oral administration [73][74]
As a result of the occurrences of vitamin K deficiency bleeding, the Committee on Nutrition of the American Academy of Pediatrics has recommended 0 5–1 mg of vitamin K1 be administered to all newborns shortly after birth [74]
In the UK vitamin K supplementation is recommended for all newborns within the first 24 hours [75] This is usually given as a single intramuscular injection of 1 mg shortly after birth but as a second-line option can be given by three oral doses over the first month [76]
Controversy arose in the early 1990s regarding this practice, when two studies suggested a relationship between parenteral administration of vitamin K and childhood cancer,[77] however, poor methods and small sample sizes led to the discrediting of these studies, and a review of the evidence published in 2000 by Ross and Davies found no link between the two [78] Doctors reported emerging concerns in 2013,[79] after treating children for serious bleeding problems  They cited lack-of newborn vitamin K administration, as the reason that the problems occurred, and recommended that breastfed babies could have an increased risk unless they receive a preventative dose 
In the early 1930s, Danish scientist Henrik Dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted diet [80] He initially replicated experiments reported by scientists at the Ontario Agricultural College (OAC) [81] McFarlane, Graham and Richardson, working on the chick feed program at OAC, had used chloroform to remove all fat from chick chow  They noticed that chicks fed only fat-depleted chow developed hemorrhages and started bleeding from tag sites [82] Dam found that these defects could not be restored by adding purified cholesterol to the diet  It appeared that – together with the cholesterol – a second compound had been extracted from the food, and this compound was called the coagulation vitamin  The new vitamin received the letter K because the initial discoveries were reported in a German journal, in which it was designated as Koagulationsvitamin  Edward Adelbert Doisy of Saint Louis University did much of the research that led to the discovery of the structure and chemical nature of vitamin K [83] Dam and Doisy shared the 1943 Nobel Prize for medicine for their work on vitamin K (K1 and K2) published in 1939  Several laboratories synthesized the compound(s) in 1939 [84]
For several decades, the vitamin K-deficient chick model was the only method of quantifying vitamin K in various foods: the chicks were made vitamin K-deficient and subsequently fed with known amounts of vitamin K-containing food  The extent to which blood coagulation was restored by the diet was taken as a measure for its vitamin K content  Three groups of physicians independently found this: Biochemical Institute, University of Copenhagen (Dam and Johannes Glavind), University of Iowa Department of Pathology (Emory Warner, Kenneth Brinkhous, and Harry Pratt Smith), and the Mayo Clinic (Hugh Butt, Albert Snell, and Arnold Osterberg) [85]
The first published report of successful treatment with vitamin K of life-threatening hemorrhage in a jaundiced patient with prothrombin deficiency was made in 1938 by Smith, Warner, and Brinkhous [86]
The precise function of vitamin K was not discovered until 1974, when three laboratories (Stenflo et al ,[87] Nelsestuen et al ,[88] and Magnusson et al [89]) isolated the vitamin K-dependent coagulation factor prothrombin (factor II) from cows that received a high dose of a vitamin K antagonist, warfarin  It was shown that, while warfarin-treated cows had a form of prothrombin that contained 10 glutamate (Glu) amino acid residues near the amino terminus of this protein, the normal (untreated) cows contained 10 unusual residues that were chemically identified as γ-carboxyglutamate (Gla)  The extra carboxyl group in Gla made clear that vitamin K plays a role in a carboxylation reaction during which Glu is converted into Gla 
The biochemistry of how vitamin K is used to convert Glu to Gla has been elucidated over the past thirty years in academic laboratories throughout the world 
^ "Vitamin K Overview"  University of Maryland Medical Center  ^ a b Higdon, Jane (Feb 2008)  "Vitamin K"  Linus Pauling Institute, Oregon State University  Retrieved 12 Apr 2008  ^ Hamidi, M  S ; Gajic-Veljanoski, O ; Cheung, A  M  (2013)  "Vitamin K and bone health"  Journal of Clinical Densitometry (Review)  16 (4): 409–413  doi:10 1016/j jocd 2013 08 017  PMID 24090644  ^ Cockayne, S ; Adamson, J ; Lanham-New, S ; Shearer, M  J ; Gilbody, S; Torgerson, D  J  (Jun 2006)  "Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials"  Archives of Internal Medicine (Review)  166 (12): 1256–1261  doi:10 1001/archinte 166 12 1256  PMID 16801507  ^ O'Keefe, J  H ; Bergman, N ; Carrera Bastos, P ; Fontes Villalba, M ; Di Nicolantonio, J  J ; Cordain, L  (2016)  "Nutritional strategies for skeletal and cardiovascular health: hard bones, soft arteries, rather than vice versa"  Open Heart (Review)  3 (1): e000325  doi:10 1136/openhrt-2015-000325  PMC 4809188  PMID 27042317  ^ Maresz, K  (Feb 2015)  "Proper Calcium Use: Vitamin K2 as a Promoter of Bone and Cardiovascular Health"  Integrative Medicine (Review)  14 (1): 34–39  PMC 4566462  PMID 26770129  ^ Hartley, L ; Clar, C ; Ghannam, O ; Flowers, N ; Stranges, S ; Rees, K  (Sep 2015)  "Vitamin K for the primary prevention of cardiovascular disease"  The Cochrane Database of Systematic Reviews (Systematic review)  9 (9): CD011148  doi:10 1002/14651858 CD011148 pub2  PMID 26389791  ^ a b Geleijnse, J  M ; Vermeer, C ; Grobbee, D  E ; Schurgers, L  J ; Knapen, M  H ; van der Meer, I  M ; Hofman, A ; Witteman, J  C  (Nov 2004)  "Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study"  Journal of Nutrition  134 (11): 3100–3105  PMID 15514282  ^ Ades, T  B , ed  (2009)  "Vitamin K"  American Cancer Society Complete Guide to Complementary and Alternative Cancer Therapies (2nd ed )  American Cancer Society  pp  558–563  ISBN 978-0-944235-71-3  ^ Lung, D  (Dec 2015)  Tarabar, A , ed  "Rodenticide Toxicity Treatment & Management"  Medscape  WebMD  ^ Rasmussen, S  E ; Andersen, N  L ; Dragsted, L  O ; Larsen, J  C  (Mar 2006)  "A safe strategy for addition of vitamins and minerals to foods"  European Journal of Nutrition  45 (3): 123–135  doi:10 1007/s00394-005-0580-9  PMID 16200467  ^ Ushiroyama, T ; Ikeda, A ; Ueki, M (Mar 2002)  "Effect of continuous combined therapy with vitamin K2 and vitamin D3 on bone mineral density and coagulofibrinolysis function in postmenopausal women"  Maturitas  41 (3): 211–221  doi:10 1016/S0378-5122(01)00275-4  PMID 11886767  ^ Asakura, H ; Myou, S ; Ontachi, Y ; Mizutani, T ; Kato, M ; Saito, M ; Morishita, E ; Yamazaki, M ; Nakao, S  (Dec 2001)  "Vitamin K administration to elderly patients with osteoporosis induces no hemostatic activation, even in those with suspected vitamin K deficiency"  Osteoporosis International  12 (12): 996–1000  doi:10 1007/s001980170007  PMID 11846334  ^ Ronden, J  E ; Groenen-van Dooren, M  M ; Hornstra, G ; Vermeer, C  (Jul 1997)  "Modulation of arterial thrombosis tendency in rats by vitamin K and its side chains"  Atherosclerosis  132 (1): 61–67  doi:10 1016/S0021-9150(97)00087-7  PMID 9247360  ^ Ansell, J ; Hirsh, J ; Poller, L ; Bussey, H ; Jacobson, A ; Hylek, E (Sep 2004)  "The pharmacology and management of the vitamin K antagonists: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy"  Chest  126 (3 Suppl ): 204S–233S  doi:10 1378/chest 126 3_suppl 204S  PMID 15383473  ^ Crowther, M  A ; Douketis, J  D ; Schnurr, T ; Steidl, L ; Mera, V ; Ultori, C ; Venco, A ; Ageno, W  (Aug 2002)  "Oral vitamin K lowers the international normalized ratio more rapidly than subcutaneous vitamin K in the treatment of warfarin-associated coagulopathy  A randomized, controlled trial"  Annals of Internal Medicine  137 (4): 251–254  doi:10 7326/0003-4819-137-4-200208200-00009  PMID 12186515  ^ a b "Important Information to Know When You Are Taking: Warfarin (Coumadin) and Vitamin K" (PDF)  National Institute of Health Clinical Center Drug-Nutrient Interaction Task Force  Retrieved 17 Apr 2015  ^ "Guidelines For Warfarin Reversal With Vitamin K" (PDF)  American Society of Health-System Pharmacists  Retrieved 17 Apr 2015  ^ "Pradaxa Drug Interactions"  Pradaxapro com  19 Mar 2012  Retrieved 21 Apr 2013  ^ Bauersachs, R ; Berkowitz, S  D ; Brenner, B ; Buller, H  R ; Decousus, H ; Gallus, A  S ; Lensing, A  W ; Misselwitz, F ; Prins, M  H ; Raskob, G  E ; Segers, A ; Verhamme, P ; Wells, P ; Agnelli, G ; Bounameaux, H ; Cohen, A ; Davidson, B  L ; Piovella, F ; Schellong, S  (Dec 2010)  "Oral rivaroxaban for symptomatic venous thromboembolism"  New England Journal of Medicine  363 (26): 2499–2510  doi:10 1056/NEJMoa1007903  PMID 21128814  ^ McGee, W  (1 Feb 2007)  "Vitamin K"  MedlinePlus  Retrieved 2 Apr 2009  ^ Shearer, M  J ; Newman, P  (Oct 2008)  "Metabolism and cell biology of vitamin K"  Thrombosis and Haemostasis  100 (4): 530–547  doi:10 1160/TH08-03-0147  PMID 18841274  ^ Davidson, R  T ; Foley, A  L ; Engelke, J  A ; Suttie, J  W  (Feb 1998)  "Conversion of dietary phylloquinone to tissue menaquinone-4 in rats is not dependent on gut bacteria"  Journal of Nutrition  128 (2): 220–223  PMID 9446847  ^ Ronden, J  E ; Drittij-Reijnders, M  J ; Vermeer, C ; Thijssen, H  H  (Jan 1998)  "Intestinal flora is not an intermediate in the phylloquinone–menaquinone-4 conversion in the rat"  Biochimica et Biophysica Acta  1379 (1): 69–75  doi:10 1016/S0304-4165(97)00089-5  PMID 9468334  ^ Thijssen, H   H ; Drittij-Reijnders, M  J  (Sep 1994)  "Vitamin K distribution in rat tissues: dietary phylloquinone is a source of tissue menaquinone-4"  The British Journal of Nutrition  72 (3): 415–425  doi:10 1079/BJN19940043  PMID 7947656  ^ Will, B  H ; Usui, Y ; Suttie, J  W  (Dec 1992)  "Comparative metabolism and requirement of vitamin K in chicks and rats"  Journal of Nutrition  122 (12): 2354–2360  PMID 1453219  ^ Davidson, R  T ; Foley, A  L ; Engelke, J  A ; Suttie, J  W  (Feb 1998)  "Conversion of dietary phylloquinone to tissue menaquinone-4 in rats is not dependent on gut bacteria"  Journal of Nutrition  128 (2): 220–223  PMID 9446847  ^ Ronden, J  E ; Drittij-Reijnders, M  J ; Vermeer, C ; Thijssen, H  H  (Jan 1998)  "Intestinal flora is not an intermediate in the phylloquinone-menaquinone-4 conversion in the rat"  Biochimica et Biophysica Acta  1379 (1): 69–75  doi:10 1016/S0304-4165(97)00089-5  PMID 9468334  ^ Al Rajabi, Ala (2011)  The Enzymatic Conversion of Phylloquinone to Menaquinone-4 (PhD thesis)  Tufts University, Friedman School of Nutrition Science and Policy  ^ Furie, B ; Bouchard, B  A ; Furie, B  C  (Mar 1999)  "Vitamin K-dependent biosynthesis of gamma-carboxyglutamic acid"  Blood  93 (6): 1798–1808  PMID 10068650  ^ Mann, K  G  (Aug 1999)  "Biochemistry and physiology of blood coagulation"  Thrombosis and Haemostasis  82 (2): 165–174  PMID 10605701  ^ Price, P  A  (1988)  "Role of vitamin-K-dependent proteins in bone metabolism"  Annual Review of Nutrition  8: 565–583  doi:10 1146/annurev nu 08 070188 003025  PMID 3060178  ^ Coutu, D  L ; Wu, J  H ; Monette, A ; Rivard, G  E ; Blostein, M  D ; Galipeau, J (Jun 2008)  "Periostin, a member of a novel family of vitamin K-dependent proteins, is expressed by mesenchymal stromal cells"  Journal of Biological Chemistry  283 (26): 17991–18001  doi:10 1074/jbc M708029200  PMID 18450759  ^ Viegas, C  S ; Simes, D  C ; Laizé, V ; Williamson, M  K ; Price, P  A ; Cancela, M  L  (Dec 2008)  "Gla-rich protein (GRP), a new vitamin K-dependent protein identified from sturgeon cartilage and highly conserved in vertebrates"  Journal of Biological Chemistry  283 (52): 36655–36664  doi:10 1074/jbc M802761200  PMC 2605998  PMID 18836183  ^ Viegas, C  S ; Cavaco, S ; Neves, P  L ; Ferreira, A ; João, A ; Williamson, M  K ; Price, P  A ; Cancela, M  L ; Simes, D  C  (Dec 2009)  "Gla-rich protein is a novel vitamin K-dependent protein present in serum that accumulates at sites of pathological calcifications"  American Journal of Pathology  175 (6): 2288–2298  doi:10 2353/ajpath 2009 090474  PMC 2789615  PMID 19893032  ^ Hafizi, S ; Dahlbäck, B  (Dec 2006)  "Gas6 and protein S  Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily"  The FEBS Journal  273 (23): 5231–5244  doi:10 1111/j 1742-4658 2006 05529 x  PMID 17064312  ^ Kulman, J  D ; Harris, J  E ; Xie, L ; Davie, E  W  (May 2007)  "Proline-rich Gla protein 2 is a cell-surface vitamin K-dependent protein that binds to the transcriptional coactivator Yes-associated protein"  Proceedings of the National Academy of Sciences of the United States of America  104 (21): 8767–8772  doi:10 1073/pnas 0703195104  PMC 1885577  PMID 17502622  ^ "Vitamin K"  MedlinePlus  US National Library of Medicine, National Institutes of Health  Sep 2016  Retrieved 26 May 2009  ^ Conly, J; Stein, K  (Dec 1994)  "Reduction of vitamin K2 concentrations in human liver associated with the use of broad spectrum antimicrobials"  Clinical and Investigative Medicine  17 (6): 531–539  PMID 7895417  ^ Ferland, G ; Sadowski, J  A ; O'Brien, M  E  (Apr 1993)  "Dietary induced subclinical vitamin K deficiency in normal human subjects"  Journal of Clinical Investigation  91 (4): 1761–1768  doi:10 1172/JCI116386  PMC 288156  PMID 8473516  ^ Holden, R  M ; Morton, A  R ; Garland, J  S ; Pavlov, A ; Day, A  G ; Booth, S  L  (Apr 2010)  "Vitamins K and D status in stages 3-5 chronic kidney disease"  Clinical Journal of the American Society of Nephrology  5 (4): 590–597  doi:10 2215/CJN 06420909  PMC 2849681  PMID 20167683  ^ Hodges, S  J ; Pilkington, M  J ; Shearer, M  J ; Bitensky, L ; Chayen, J (Jan 1990)  "Age-related changes in the circulating levels of congeners of vitamin K2, menaquinone-7 and menaquinone-8"  Clinical Science  78 (1): 63–66  PMID 2153497  ^ "Vitamin K"  Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc (PDF)  National Academy Press  2001  p  162–196  ^ Tolerable Upper Intake Levels For Vitamins And Minerals (PDF), European Food Safety Authority, 2006 ^ a b Rhéaume-Bleue, p  42
^ "Important information to know when you are taking: Warfarin (Coumadin) and Vitamin K" (PDF)  National Institutes of Health Clinical Center  ^ "Nutrition Facts and Information for Parsley, raw"  Nutritiondata com  Retrieved 21 Apr 2013  ^ "Nutrition facts, calories in food, labels, nutritional information and analysis"  Nutritiondata com  13 Feb 2008  Retrieved 21 Apr 2013  ^ "Vitamin K"  Vivo colostate edu  2 Jul 1999  Retrieved 21 Apr 2013  ^ "Vitamin K"  Micronutrient Data Centre  ^ Ikeda, Y ; Iki, M ; Morita, A ; Kajita, E ; Kagamimori, S ; Kagawa, Y ; Yoneshima, H  (May 2006)  "Intake of fermented soybeans, natto, is associated with reduced bone loss in postmenopausal women: Japanese Population-Based Osteoporosis (JPOS) Study"  Journal of Nutrition  136 (5): 1323–1328  PMID 16614424  ^ Katsuyama, H ; Ideguchi, S ; Fukunaga, M ; Saijoh, K ; Sunami, S  (Jun 2002)  "Usual dietary intake of fermented soybeans (Natto) is associated with bone mineral density in premenopausal women"  Journal of Nutritional Science and Vitaminology  48 (3): 207–215  doi:10 3177/jnsv 48 207  PMID 12350079  ^ Sano, M ; Fujita, H ; Morita, I ; Uematsu, H ; Murota, S  (Dec 1999)  "Vitamin K2 (menatetrenone) induces iNOS in bovine vascular smooth muscle cells: no relationship between nitric oxide production and gamma-carboxylation"  Journal of Nutritional Science and Vitaminology  45 (6): 711–723  doi:10 3177/jnsv 45 711  PMID 10737225  ^ Gast, G  C ; de Roos, N  M ; Sluijs, I ; Bots, M  L ; Beulens, J  W ; Geleijnse, J  M ; Witteman, J  C ; Grobbee, D  E ; Peeters, P  H ; van der Schouw, Y  T  (Sep 2009)  "A high menaquinone intake reduces the incidence of coronary heart disease"  Nutrition, Metabolism, and Cardiovascular Diseases  19 (7): 504–510  doi:10 1016/j numecd 2008 10 004  PMID 19179058  ^ Oldenburg, J ; Bevans, C  G ; Müller, C  R ; Watzka, M  (2006)  "Vitamin K epoxide reductase complex subunit 1 (VKORC1): the key protein of the vitamin K cycle"  Antioxidants & Redox Signaling  8 (3–4): 347–353  doi:10 1089/ars 2006 8 347  PMID 16677080  ^ Suttie, J  W  (1985)  "Vitamin K-dependent carboxylase"  Annual Review of Biochemistry  54: 459–477  doi:10 1146/annurev bi 54 070185 002331  PMID 3896125  ^ Presnell, S  R ; Stafford, D  W  (Jun 2002)  "The vitamin K-dependent carboxylase"  Thrombosis and Haemostasis  87 (6): 937–946  PMID 12083499  ^ Stafford, D  W  (Aug 2005)  "The vitamin K cycle"  Journal of Thrombosis and Haemostasis  3 (8): 1873–1878  doi:10 1111/j 1538-7836 2005 01419 x  PMID 16102054  ^ Rhéaume-Bleue, p  79 
^ Whitlon, D  S ; Sadowski, J  A ; Suttie, J  W  (Apr 1978)  "Mechanism of coumarin action: significance of vitamin K epoxide reductase inhibition"  Biochemistry  17 (8): 1371–1377  doi:10 1021/bi00601a003  PMID 646989  ^ Terlau, H ; Olivera, B  M  (Jan 2004)  "Conus venoms: a rich source of novel ion channel-targeted peptides"  Physiological Reviews  84 (1): 41–68  doi:10 1152/physrev 00020 2003  PMID 14715910  ^ Buczek, O ; Bulaj, G ; Olivera, BM (Dec 2005)  "Conotoxins and the posttranslational modification of secreted gene products"  Cellular and Molecular Life Sciences  62 (24): 3067–3079  doi:10 1007/s00018-005-5283-0  PMID 16314929  ^ "Prothrombin Time"  WebMD  ^ Dituri, F ; Buonocore, G ; Pietravalle, A ; Naddeo, F ; Cortesi, M; Pasqualetti, P; Tataranno M  L ; R , Agostino (Sep 2012)  "PIVKA-II plasma levels as markers of subclinical vitamin K deficiency in term infants"  Journal of Maternal, Fetal & Neonatal Medicine  25 (9): 1660–1663  doi:10 3109/14767058 2012 657273  PMID 22280352  ^ Thane, C  W ; Bates, C  J ; Shearer, M  J ; Unadkat, N; Harrington, D  J ; Paul, A  A ; Prentice, A ; Bolton-Smith, C  (Jun 2002)  "Plasma phylloquinone (vitamin K1) concentration and its relationship to intake in a national sample of British elderly people"  British Journal of Nutrition  87 (6): 615–622  doi:10 1079/BJNBJN2002582  PMID 12067432  ^ McKeown, N  M ; Jacques, P  F ; Gundberg, C  M ; Peterson, J  W ; Tucker, K  L ; Kiel, D  P ; Wilson, P  W ; Booth, SL (Jun 2002)  "Dietary and nondietary determinants of vitamin K biochemical measures in men and women" (PDF)  Journal of Nutrition  132 (6): 1329–1334  PMID 12042454  ^ Yamano, M ; Yamanaka, Y ; Yasunaga, K ; Uchida, K  (Sep 1989)  "Effect of vitamin K deficiency on urinary gamma-carboxyglutamic acid excretion in rats"  Nihon Ketsueki Gakkai Zasshi  52 (6): 1078–1086  PMID 2588957  ^ Matsumoto, T ; Miyakawa, T ; Yamamoto, D  (Mar 2012)  "Effects of vitamin K on the morphometric and material properties of bone in the tibiae of growing rats"  Metabolism  61 (3): 407–414  doi:10 1016/j metabol 2011 07 018  PMID 21944271  ^ Je, S -H ; Joo, N -S ; Choi, B -H ; Kim, K -M ; Kim, B -T ; Park, S -B ; Cho, D -Y ; Kim, K -N ; Lee, D -J  (Aug 2011)  "Vitamin K supplement along with vitamin D and calcium reduced serum concentration of undercarboxylated osteocalcin while increasing bone mineral density in Korean postmenopausal women over sixty-years-old"  Journal of Korean Medical Science  26 (8): 1093–1098  doi:10 3346/jkms 2011 26 8 1093  PMC 3154347  PMID 21860562  ^ Bentley, R ; Meganathan, R  (Sep 1982)  "Biosynthesis of vitamin K (menaquinone) in bacteria" (PDF)  Microbiological Reviews  46 (3): 241–280  PMC 281544  PMID 6127606  ^ Haddock, B  A ; Jones, C  W  (Mar 1977)  "Bacterial respiration" (PDF)  Bacteriological Reviews  41 (1): 47–99  PMC 413996  PMID 140652  ^ Shearer, M  J  (Jan 1995)  "Vitamin K"  Lancet  345 (8944): 229–234  doi:10 1016/S0140-6736(95)90227-9  PMID 7823718  ^ Greer, J  P ; Foerster, J ; Lukens, J  N ; Rodgers, G  M ; Paraskevas, F ; Glader, B  (eds )  Wintrobe's Clinical Hematology (11th ed )  Philadelphia, Pennsylvania: Lippincott, Williams and Wilkens  ^ a b American Academy of Pediatrics Committee on Fetus Newborn  (Jul 2003)  "Controversies concerning vitamin K and the newborn  American Academy of Pediatrics Committee on Fetus and Newborn" (PDF)  Pediatrics  112 (1 1): 191–192  doi:10 1542/peds 112 1 191  PMID 12837888  ^ Logan, S ; Gilbert, R  (1998)  "Vitamin K For Newborn Babies" (PDF)  Department of Health  Retrieved 12 Oct 2014  ^ "Postnatal care: Routine postnatal care of women and their babies [CG37]"  www nice org uk  NICE  Jul 2006  Retrieved 12 Oct 2014  ^ Parker, L ; Cole, M ; Craft, A  W ; Hey, E  N  (1998)  "Neonatal vitamin K administration and childhood cancer in the north of England: retrospective case-control study"  BMJ (Clinical Research Edition)  316 (7126): 189–193  doi:10 1136/bmj 316 7126 189  PMC 2665412  PMID 9468683  ^ McMillan, D  D  (1997)  "Routine administration of vitamin K to newborns"  Paediatric Child Health  2 (6): 429–431  ^ "Newborns get rare disorder after parents refused shots"  Having four cases since February just at Vanderbilt was a little bit concerning to me ^ Dam, C  P  H  (1935)  "The Antihaemorrhagic Vitamin of the Chick: Occurrence And Chemical Nature"  Nature  135 (3417): 652–653  doi:10 1038/135652b0  ^ Dam, C  P  H  (1941)  "The discovery of vitamin K, its biological functions and therapeutical application" (PDF)  Nobel Prize Laureate Lecture  ^ McAlister, V  C  (2006)  "Control of coagulation: a gift of Canadian agriculture" (PDF)  Clinical and Investigative Medicine  29 (6): 373–377  ^ MacCorquodale, D  W ; Binkley, S  B ; Thayer, S  A ; Doisy, E  A  (1939)  "On the constitution of Vitamin K1"  Journal of the American Chemical Society  61 (7): 1928–1929  doi:10 1021/ja01876a510  ^ Fieser, L  F  (1939)  "Synthesis of Vitamin K1"  Journal of the American Chemical Society  61 (12): 3467–3475  doi:10 1021/ja01267a072  ^ Dam, C  P  H  (12 Dec 1946)  "The discovery of vitamin K, its biological functions and therapeutical application" (PDF)  Nobel Prize lecture  ^ Warner, E  D ; Brinkhous, K  M ; Smith, H  P  (1938)  "Bleeding Tendency of Obstructive Jaundice"  Proceedings of the Society of Experimental Biology and Medicine  37 (4): 628–630  doi:10 3181/00379727-37-9668P  ^ Stenflo, J; Fernlund, P ; Egan, W ; Roepstorff, P  (Jul 1974)  "Vitamin K dependent modifications of glutamic acid residues in prothrombin"  Proceedings of the National Academy of Sciences of the United States of America  71 (7): 2730–2733  doi:10 1073/pnas 71 7 2730  PMC 388542  PMID 4528109  ^ Nelsestuen, G  L ; Zytkovicz, T  H ; Howard, J  B  (Oct 1974)  "The mode of action of vitamin K  Identification of gamma-carboxyglutamic acid as a component of prothrombin" (PDF)  Journal of Biological Chemistry  249 (19): 6347–6350  PMID 4214105  ^ Magnusson, S ; Sottrup-Jensen, L ; Petersen, T  E ; Morris, H  R ; Dell, A  (Aug 1974)  "Primary structure of the vitamin K-dependent part of prothrombin"  FEBS Letters  44 (2): 189–193  doi:10 1016/0014-5793(74)80723-4  PMID 4472513  Bibliography[edit]
Rhéaume-Bleue, Kate (2012)  Vitamin K2 and the Calcium Paradox  John Wiley & Sons, Canada  ISBN 1-118-06572-7  External links[edit]
"Vitamin K: Another Reason to Eat Your Greens"  v
TPP / ThDP (B1)
FMN, FAD (B2)
NAD+, NADH, NADP+, NADPH (B3)
Coenzyme A (B5)
PLP / P5P (B6)
THFA / H4FA, DHFA / H2FA, MTHF (B9)
AdoCbl, MeCbl (B12)
Phylloquinone (K1), Menaquinone (K2)
non-vitamins
Coenzyme B
Heme / Haem (A, B, C, O)
Molybdopterin/Molybdenum cofactor
THMPT / H4MPT
Fe2+, Fe3+
vitamins: see vitamins
Antihemorrhagics (B02)
(coagulation)
Phytomenadione (K1)
Menadione (K3)
intrinsic: IX/Nonacog alfa
VIII/Moroctocog alfa/Turoctocog alfa
extrinsic: VII/Eptacog alfa
common: X
II/Thrombin
I/Fibrinogen
XIII/Catridecacog
combinations: Prothrombin complex concentrate (II, VII, IX, X, protein C and S)
Carbazochrome
thrombopoietin receptor agonist (Romiplostim
Eltrombopag)
Tetragalacturonic acid hydroxymethylester
Epinephrine/Adrenalone
amino acids (Aminocaproic acid
Aminomethylbenzoic acid)
serpins (Aprotinin
Alfa1 antitrypsin
Camostat) 
Context 2: The Official 2006 NBA Draft Early-Entry List  30 International Players, 62 underclassmen and one lone 5th year high school player make up this year's list, for a total of 93 early-entrants  Extensive commentary and early draft status projections are included   For comparison, in 2005, 108 players declared (61 NCAA, 12 high school, 35 internationals), up from 94 in 2004, and 73 in 2003 
There were no major surprises on the early-entry list, besides a few mid-major, Division II and NAIA players that decided to enter, as well as 5th year high school player Clarence Holloway  Amongst the International players, Hrvoje Peric, Renaldas Seibutis, and Kyrylo Fesenko are considered mild surprises who could end up cracking the 2nd round  NCAA Lottery prospects Joakim Noah, Al Horford, Corey Brewer, Josh McRoberts, Brandon Rush and Tyler Hansbrough decided to sit this one out as expected, as did Marco Belinelli, Uros Tripkovic and Goran Dragic on the international front 
Akbar Abdul-Ahad 6-0, PG, Idaho State Junior No Undrafted Averaged under 6 points in 20 minutes per game playing in the Big Sky  Being the first player on the NBA Draft Early-Entry list will likely go down as the highlight of his basketball career 
Arron Afflalo, 6-5, SG, UCLA Sophomore No Undrafted Afflalo initially told the LA media hes returning to school, but after a deep run in the NCAA tournament-- more in spite of his play than because of it--Afflalo will be testing the waters  Afflalo has very average size, athleticism, perimeter shooting and ball-handling skills  Hes clearly receiving bad advice on where his stock lies 
LaMarcus Aldridge, 6-11, PF/C, Texas Sophomore Yes Top 5 pick Aldridge made his announcement official to enter the draft some weeks ago  He will hire an agent soon (Arn Tellem?) and is considered a lock for the top 5 and a strong candidate for #1 overall 
Morris Almond, 6-6, SG, Rice Junior No ??? Almond announced hell be entering the draft, without an agent  He might be the best scorer in the NCAA youve never heard about  His stats are terrific, despite being the sole focal point of opposing defenses, and hes capable of scoring in a variety of ways, particularly with his jumper  Hes hoping for an invite to Orlando 
Renaldo Balkman, 6-8, PF, South Carolina Junior No Undrafted After winning the NIT MVP award, Balkman has decided to see where he stands in the eyes of the NBA by testing the waters  Hes likely to find them downright freezing, as hes a skinny and undersized power forward with little to no skills who came off the bench for a very average team 
Larry Blair,6-1, SG, Liberty Junior No Undrafted The 22 point per game scorer Blair is attempting to get some exposure for himself by testing the waters 
Will Blalock, Iowa State, 5-11, PG, Junior No Second round pick? Declared for the draft together with Curtis_Stinson after Iowa States coach was fired  Size is a big question mark  Will likely hope to attend the pre-draft camp in Orlando and try to show scouts hes a 1st rounder  Likely returns for his senior year 
Jahsha Bluntt, 6-6, SG, Deleware State Junior No Undrafted Puts up fairly average numbers (14 6 ppg, 41% FG) in one of the worst conferences in America  Looking for exposure at the Orlando pre-draft camp but its highly unlikely to receive it 
Josh Boone, 6-10, PF/C, UConn Junior No First round pick? Boone announced hell be entering the draft without an agent  An up and down season has left his stock in the air, and will likely force him to prove himself at the Orlando pre-draft camp  Would greatly benefit from a productive senior season as an offensive focal point now that UConn has lost almost all of its firepower from last year 
Ronnie Brewer, 6-6, PG/SG, Arkansas Junior No Lottery pick? After initially wavering a bit on his decision, Brewer announced hell be entering the draft without an agent in a press conference  Brewer is considered a likely late lottery pick to mid-first rounder pick, as his physical attributes and array of versatile skills on both ends of the floor are highly sought after 
Bobby Brown, 6-1, PG, Cal-State Fullerton Junior No First round pick? DraftExpress exclusively reported that Brown will be testing the waters  Still considered a bit of a sleeper because of the school he plays for, he will not be hiring an agent at this point  Some scouts are very high on his quickness and perimeter shooting ability and feel he will help his stock tremendously in private workouts 
Shannon Brown, 6-4, SG, Michigan State Junior No First round pick? As exclusively reported by DraftExpress, Brown will be testing the waters  He will likely conduct a number of workouts and attend the Orlando pre-draft camp to attempt and gauge where his stock lies  Scouts compare him to Celtic guard Tony Allen, but with a better attitude  Hes a very borderline first rounder in a draft that is stacked with shooting guards 
Derek Burditt, 6-7, SG, Blinn Junior College Sophomore No Undrafted Unknown Junior College prospect  Not ranked as one of the top 25 JUCO players in the country, averaged around 17 points per game  Not burning his draft card as hes not yet an NCAA player, so really doesnt have much to lose, or gain 
Leroy Dawson, 6-2, SG, Emporia State Junior No Undrafted Anonymous Division II player from the MIAA conference  2nd team all conference, averaged 20 points per game  Like MANY on this list, only declaring because he can and has nothing to lose 
Travis DeGroot, 6-4, SG, Delta State Junior No Undrafted Plays in a strong Division II conference, but is at best only the 3rd best prospect on his own team after Jasper Johnson and Jeremy Richardson, and is therefore not a prospect at all 
Guillermo Diaz, 6-2, PG/SG, Miami Junior Yes First round pick? As reported by DraftExpress all year long, Diaz decided to forgo his senior year of college by hiring an agent, Miami based Jason Levien  One of the top athletes and shooters in the draft, which makes for an intriguing combination 
Cem Dinc, 6-10, SF/PF, Indiana Freshman No Undrafted As exclusively reported by DraftExpress, Dinc will be testing the waters  The coach that recruited him and then never played him, Mike Davis, resigned, so it would not shock anyone to see Dinc return to play in Europe and become automatically eligible next year after pulling out of this years draft 
Quincy Douby, 6-3, PG/SG, Rutgers Junior No First round pick As exclusively reported by DraftExpress, Douby sent out his paperwork to enter the draft  NBA scouts are all over the board on him, with some saying they consider him a 2nd round pick and others saying they would not be surprised if he ended up in the lottery  Terrific shooter and shot creator, averaged 28 ppg in the Big East conference  A real sleeper who will likely play in Orlando 
Mike Efevberha, 6-5, SG, Cal State Northridge Junior ??? Undrafted Ramona Shelburne of the LA Daily News reported that Efevberha will be testing the waters  Efevberha was the leading scorer in the country until he had a falling out with his coach and saw his playing time reduced significantly  Hell likely be looking for an invite to the Orlando pre-draft camp, and does not appear to be likely to head back to school 
Carl Elliot, 6-4, PG, George Washington Junior No Undrafted Elliot is using his use it or lose it draft card as a junior to get some exposure for himself through workouts and try to figure out where he stands in the eyes of the NBA  Elliot has excellent size for the PG position, but is still lacking plenty of all-around polish  His senior year will be essential to his development as a player  Reportedly has a family to support, which makes his decision tough considering how old he is already, despite only being a junior 
Jordan Farmar, 6-2, PG, UCLA Sophomore No First round pick? Farmar was the engine that led his team to the Finals of the NCAA tournament, and the only player that showed up once they got there  He is one of the top playmakers in the country, a Steve Nash type point guard, but his average athleticism, defense and outside shooting means hes only a bubble first-rounder  DraftExpress has been on his bandwagon since day one at UCLA, but is the NBA on it too?
Nick Fazekas, 6-11, PF, Nevada Junior No First round pick? Fazekas announced hell be entering the draft without an agent and will likely return to Nevada if it looks like hes not going to be a first round pick  If hes not a first rounder this year, its hard to imagine him ever being one since there isnt much left for him to accomplish individually in the NCAA  An interesting candidate for the pre-draft camp in Orlando 
Thomas Gardner, 6-5, SG, Missouri Junior No Second round pick? The St  Louis Post Dispatch reported that Gardner will enter the draft  Firing of underachieving Missouri coach Quin Snyder appeared to be the straw the broke the camels back  Gardner will have to hope to get invited to Orlando, but moving into the first round appears unlikely without an incredible performance there 
Rudy Gay, 6-8, SF, UConn Sophomore Yes Top 10 pick Gay announced hes leaving UConn at a press conference on campus, with Coach Calhoun by his side  He will hire an agent eventually  Size, length, incredible talent and athleticism means he might have the most upside of any player in this draft  Does he have the fire to capitalize on it though?
Reggie George, 6-10, PF, Robert Morris Chicago (NAIA) Junior No Undrafted Transfer from Iowa State had a nice season in the NAIA and is looking to capitalize on it by gaining some exposure for himself 
Daniel Gibson, 6-2, PG/SG, Texas Sophomore ??? Second round pick As exclusively reported by DraftExpress, Gibson will be entering the draft  There appears to be a conflict between Gibson and Texas regarding what his role will be next year, specifically whether or not hell be playing the point, meaning its unclear whether or not hell be returning  Gibson will likely go to Orlando to help him decide what his next step is  Showing off some PG skills will be essential there 
Aaron Gray, 7-0, Center, Pitt Junior No First round pick? After a disappointing end to his season, being outplayed by Patrick OBryant in the NCAA tournament, Gray has put that behind him and entered his name in the draft without an agent  Hes yet another underclassmen with huge questions marks about his pro potential that will likely have to go to the Orlando pre-draft camp to show he is worthy of a first round pick  Made some great strides this year, but still has a ways to go, especially conditioning-wise 
LeShawn Hammett 6-0, PG, St  Francis Junior No Undrafted Undersized combo guard played only 7 minutes in the mighty Northeast Conference before being suspended indefinitely for conduct detrimental to team  The NBA is clearly the only goal left for him to achieve 
Brandon Heath, 6-3, PG/SG, San Diego State Junior No Second round pick? Streaky shooting combo guard Heath announced the he will test the NBA draft process this summer, and is hoping for an invite to the Orlando pre-draft camp  MWC player of the year; has a lot of wrinkles to his game that need to be ironed out before he can legitimately think about the NBA 
Tedric Hill, 6-10, PF, Gulf Coast Community College Sophomore Yes Undrafted Ineligible to return to school after flunking out of college once again  Has bounced around over the past few years, and received some early hype from wannabe draftniks such as Gregg Doyel (CBS-Sportsline) and Sam Smith (Chicago Tribune) who compare him to Kevin Garnett  Very athletic we're told, but has absolutely no idea how to play the game  Has no chance of being drafted without an amazing showing at the Orlando pre-draft camp 
Clarence Holloway 7-0, Center, IMG Academy (Prep School) 5th year High School No Undrafted Lone high school player in this years age-limit depleted draft  Former Louisville commit never got eligible for college and was always considered too slow and heavy to make much of an impact anyway  Reportedly lost weight and improved his grades this past year at IMG and is currently being recruited by UConn, Kansas State and Oklahoma, amongst others 
Ekene Ibekwe, 6-9, PF, Maryland Junior No Undrafted Sources told DraftExpress exclusively that Ibekwe will be testing the waters  Likely only making this move because he can, as his chances of being drafted are very low  Athletic and long, but still lacking any type of polish 
Donald Jeffers, 6-8, PF, Roxbury Community College Sophomore No Undrafted Anonymous junior college player 
Alexander Johnson, 6-9, PF, Florida State Junior Yes First round pick? Sources told DraftExpress, that Johnson will be hiring an agent, mainly because he is already 23 years old  Hes considered intriguing because of his strength, raw offensive tools and freakish athleticism at the 4 position, and could work his way into the 1st round with strong workouts 
David Johnson, 6-7, PF, Clinton Junior College Sophomore No Undrafted 6-7 JUCO power forward who averaged 2 points and 3 rebounds per game 
Trey Johnson, 6-5, SG, Jackson State Junior No Undrafted Small school prolific scorer and one of the most accurate perimeter shooters in the country will attempt to draw some more attention to himself by testing the waters this summer  Johnson is hoping for a chance to prove himself in the Orlando pre-draft camp in June 
Coby Karl, 6-4, PG/SG, Boise State Junior No Undrafted Son of Denver Nuggets head Coach George Karl put up nice numbers (17 ppg, 5 rebs, 4 assists, 39 5% 3P) in the underrated WAC conference  Had surgery in March to remove a cancerous lump from his thyroid 
Mark Konecny, 6-10, Center, Lambuth (NAIA) Junior No Undrafted Transfer from Syracuse with mediocre production is looking for any type of exposure he can get before he graduates next season 
Kyle Lowry, 6-1, PG, Villanova Sophomore No First round pick NCAA tournament performance showed that he definitely needs another year, but regardless, Lowry is in  For now its without an agent  Considering the lack of quality point guard prospects in this draft, Lowry is likely a first round pick  Says he will attend the Orlando pre-draft camp if invited 
Aleks Maric, 6-11, Center, Nebraska Sophomore No Undrafted As exclusively reported by DraftExpress, Maric will be testing the waters  What may have played a role in this is the fact that the assistant coach that recruited him at Nebraska, Scott Spinelli, just moved on to Wichita State  Maric is considered a very average athlete who is still very raw and is therefore likely to go undrafted should he decide to stay in  Thanks to his Croatian passport, there is money waiting for him overseas if he chooses to take it 
Japhet McNeil, 5-10, PG, East Carolina Junior No Undrafted Severely undersized PG averaged 4 points and 5 6 assists in watered down Conference USA 
Paul Millsap, 6-8, PF, Louisiana Tech Junior Yes First round pick? As expected, Millsap has declared his intentions to enter the NBA draft, and according to sources hired an agent as well  Millsap has likely achieved just about everything he can in college at this point, and will land somewhere in the 20-40 part of the draft depending on workouts and measurements 
Matt Mitchell, 6-0, PG, Southern University-New Orleans Junior No Undrafted Anonymous NAIA player 
Adam Morrison, 6-8, SF, Gonzaga Junior Yes Top 5 pick As DraftExpress exclusively reported that Morrison will be declaring for the draft and hiring Chicago based agent Mark Bartelstein  Morrison, the top scorer in college basketball, is expected to be a top 5 pick and potentially the #1 pick overall  Questions linger about his athleticism and defense, but no one questions his passion, talent or feel for the game 
Patrick O'Bryant, 7-0, Center, Bradley Sophomore Likely First round pick NBA sources in Portsmouth told DraftExpress exclusively that OBryant will be testing the waters without an agent, but is likely to go all the way once he hears that hes a lock for the 1st round  His steady improvement, strong sophomore season, outstanding NCAA tournament and considerable upside means hes probably gone  O'Bryant since confirmed both DraftExpresss reports, particularly the one about hiring an agent in the Tri-State area (Andy Miller) should he decide to go all the way 
Evan Patterson, 6-7, SF, Texas Wesleyan Junior No Undrafted Mediocre numbers (11 ppg, 2 rebs) in a mediocre Southland conference 
Danilo Pinnock, 6-5, SG, George Washington Junior No Undrafted The extremely athletic Pinnock has told GWs student paper hell be testing the waters  Pinnock will attempt to capitalize on his teams success this year by potentially attending the NBA pre-draft camp in Orlando  Pinnock will have to show better ball-handling and perimeter shooting ability than he did during the regular season 
Leon Powe, 6-7, PF, Cal Sophomore No Second round pick Powe announced hell be testing the waters in a statement released by Cal  Where he ends up being projected depends heavily on how his knee checks out  Powe is already considered a serious tweener by NBA scouts, and had a hard time this season gaining back much of the explosiveness he had earlier in his career  Could realistically go undrafted should he decide to stay in 
Richard Roby, 6-5, SG, Colorado Sophomore Likely Second round pick As first indicated by DraftExpress Roby has decided to test the waters  Disappeared against any major competition he went up against, particularly towards the end of the season  Roby will likely have to put on weight in the next few months and show off his perimeter stroke in the Orlando pre-draft camp  Sources tell us that he is on the verge of making a huge mistake by hiring an agent



ground_truth: Vitamins K3, K4, and K5.

prompt_front: Now, answer the following question based on the text below, only give me the answer and do not output any other words.

Question: How many underclassmen are on the NBA Draft Early-Entry List?

Read the following text and answer briefly.

Context 2: 
Rajon Rondo, 6-2, PG, Kentucky Sophomore Yes First round pick As expected, Rondo has decided to enter the NBA draft, and has also hired an agent, Bill Duffy  Despite an inconsistent sophomore season, most scouts weve spoken to still had him as at least the #2 point guard on their board because of his intriguing upside  Workouts will be huge for him 
Blake Schilb, 6-7, SG/SF, Loyola Chicago Junior No Undrafted Declared his intentions to enter the draft, without an agent, and is hoping for an invite to Orlando  Schlib is sorely lacking in the quickness and explosiveness departments that scouts demand from swingman prospects, but he makes up for it with his skill set to a certain extent  Regardless, sources tell us he wont be invited to Orlando, meaning he has to go back to school 
Mustafa Shakur, 6-4, PG, Arizona Junior No Second round pick? According to the Arizona Star, Shakur will likely enter his name in the draft, without an agent  Lute Olson confirmed it, saying he is not concerned about it  Shakur is hoping for an Orlando invite to show what he thinks he couldnt at Point Guard U 
Cedric Simmons, 6-9, PF/C, NC State Sophomore No First round pick? Simmons is reportedly "exploring his options," in regards to the 2006 NBA draft, but will do so without an agent  Nice size, frame, length, athleticism and defensive skills make him a very intriguing prospect 
Marcus Slaughter, 6-8, PF, San Diego State Junior Yes Second round pick? After burning his lone draft card a year early last June, despite being considered a marginal prospect, Slaughter has announced that he will be hiring agent Dan Fegan and forfeiting his remaining college eligibility  Slaughters father thinks that There was nothing else for Marcus to do at San Diego State  Many would disagree with that 
Curtis Stinson, 6-3, PG/SG, Iowa State Junior Yes Second round pick After swearing up and down last month that he has no intention on entering the draft, Stinson did just that  His coach Wayne Morgan, who he was very close to, was fired, resulting in him hiring agent Kevin Bradbury  The 23 year old combo guard will have to go to the Orlando pre-draft camp and impress if he wants to come close to being a 1st rounder 
Tyrus Thomas, 6-9, PF, LSU Freshman Yes Top 5 pick As DraftExpress exclusively reported Thomas called a press conference to announce his intentions to enter the 2006 NBA draft, as well as hire agents Brian Elfus and Mike Siegel  SEC Freshman of the year could be the most athletic player in the draft, as well as the player with the most overall upside 
PJ Tucker, 6-5, SF, Texas Junior No Second round pick As reported all year long by DraftExpress, Tucker will be entering the draft without an agent  Considering that hes a 6-5 combo forward with tremendous skills, his stock widely fluctuates depending on who is being asked  Phenomenal basketball player, but is severely lacking in 2-3 inches of height  Will likely need a strong showing at the Orlando pre-draft camp to have a legitimate shot at the 1st round  Some scouts compare him to Bonzi Wells 
Junior No Undrafted Undersized Division II post player has no chance of being drafted despite 20+8 averages 
Ian Vouyoukas, 6-10, Center, St  Louis Junior ??? Undrafted Vouyoukas declared his intentions to enter the draft, supposedly without an agent  Sources in Europe tell us he is likely to return to Greece to take a large contract offer from a first division team once he realizes he has no chance of being drafted  Vouyoukas is a nice mid-major big man who has improved somewhat in his junior season, but does not possess the necessary combination of athleticism and size required of an NBA center 
Darius Washington, 6-2, PG, Memphis Sophomore Likely First round pick? DraftExpress exclusively reported that Washington will be in the draft  It appears that hell be hiring an agent as well, despite not being anywhere near a lock for the first round 
Albert Weber, 6-3, SG, Connors State Sophomore No Undrafted Transfer from Alabama led his conference in scoring and is considered one of the top Junior College players in the country  Not officialy an NCAA player yet, and has not committed to any school yet, so really doesn't stand much to lose (or gain) from this move 
Marcus Williams, 6-3, PG, UConn Junior Yes Late Lottery-Mid-First As expected, Williams is expected to announce that hes hired Calvin Andrews of BDA Sports Management as his agent at a press conference next week  A strong junior season and outstanding NCAA tournament, establishing himself as one of the purest playmakers in the nation, means hes likely one of the first PGs taken 
Andriy Agafonov, 6-8, PF, Khimik 1986 Ukraine Undrafted Ukrainian power forward played 15 minutes and scored 6 points with 4 4 rebounds per game playing for FIBA EuroCup participants, and is declaring in hopes of getting his name out as he has one more draft card to burn after this before becoming automatically eligible 
Nemanja Aleksandrov, 7-0, SF/PF, KK Reflex 1987 Serbia & Montenegro ??? American agent has been telling us all year that hes likely to enter  Still hasnt played a game this year after taking slow recovery process from torn ACL  Once regarded as a prodigy and potential #1 overall pick, but injuries mean he hasnt played in nearly two years and is now considered damaged goods  Might just look for an attractive team to guarantee him in the 2nd round and develop him in the NBDL 
Pape-Philippe Amagou, 6-1, PG, Le Mans 1985 France ??? Amagous American agent has informed us that he will enter the NBA Draft this year, and participate in the Reebok Eurocamp in Treviso  Shares playmaking duties and spotlight with fellow early-entrant Yannick Bokolo 
Andrea Bargnani, 7-0, PF, Benetton Treviso 1985 Italy Top 5 pick Bargnani's Italian agent Stefano Meller told DraftExpress in Portsmouth that the Italian star power forward will definitely be entering the NBA draft  Bargnani is in the process of hiring an American agent and the only question is how long will it take for him to make it over to the US after Benetton finishes up in the Italian playoffs, which could last as far as mid-June  He is expected to be a top 5 pick with a shot at going #1 depending on how the lottery plays out  Considered a phenomenal talent thanks to his excellent size, perimeter skills and athleticism relative to height 
Yannick Bokolo, 6-3, PG/SG, Le Mans 1985 France ??? Terrific athlete who is still making the transition to playing the point full time 
Carlos Cedeno, 6-5, SG, Guaiqueries 1985 Venezuela Undrafted Relatively unknown Venezuelan player  Has some international experience at the junior levels 
Tadija Dragicevic, 6-8, PF, Red Star Belgrade 1986 Serbia & Montenegro Undrafted Undersized power forward barely played in the Adriatic League this past season 
Lior Eliyahu, 6-9, SF/PF, Galil Elyon 1985 Israel Second round pick? Prolific and athletic Israeli combo forward will be entering the NBA draft this year looking for certain guarantees from an NBA team in the 1st or 2nd round  Eliyahu is still in the Israeli army and will stay overseas for another year regardless of what happens  He'll be represented by the American agency Entersport in the United States  A midseason injury set him back from being the top Israeli player in the league despite his youth 
Rudy Fernández, 6-5, SG, DKV Joventut 1985 Spain First round pick? Has some minor buyout issues to deal with to make sure he can stay in the draft  Excellent season in Spain has him projected as a pretty solid first round pick  Improved outside shooting, and still the same excellent athlete, passer, defender and all-around player hes always been  Still very skinny too 
Kyrylo Fesenko, 6-11, PF, Azovmash 1986 Ukraine Second Round Pick More to come 
Rafael Hettsheimeir, 6-9, Center, Akasvayu Girona 1986 Brazil Undrafted Undersized Brazilian center did not overly impress at the Nike Hoop Summit, showing that he will likely lack mobility until he takes off some weight 
Marko Lekic, 6-11, PF, Atlas 1985 Serbia & Montenegro ??? American agent Marc Cornstein, Lekic told us hell be putting his name in the draft this year once again  Still a bit of an unknown, numbers are fairly average in the Serbian YUBA league 
Damir Markota, 6-11, SF/PF, Cibona Zagreb 1985 Croatia Second round pick American agent Marc Cornstein told us Markota will definitely be putting his name in the draft once again  He had a breakout season in the Euroleague and Adriatic league before a groin injury slowed him down and eventually forced him to have minor surgery  Likely wont be able to come to the States until very late in the process  Does not have a buyout 
Mickael Mokongo, 5-11, PG, Chalon 1986 France ??? DraftExpress was exclusively informed hell be in the draft  Considered a talented athlete, but lack of size and the fact that he missed a large chunk of the season due to injury means his draft stock is very much up in the air still 
Brad Newley, 6-6, SG, 1985 Australia Second round pick Newely has told the Australian media that hes entering the draft  Hired Philadelphia based agent Leon Rose  Scouts who saw him play in Argentina last summer like his athleticism  Desperately lacking exposure, but agent appears to be unwilling to provide him with it 
Oleksiy Pecherov, 6-11, PF, Racing Basket 1985 Ukraine Second round pick DraftExpress received indication that Pecherov will be entering his name in the draft after a nice 2nd half regular season in France  Pecherov has his draft card in hand one year before he becomes automatically eligible, meaning he has nothing to lose  Has some nice skills facing the basket, but is still very soft and underdeveloped 
Hrvoje Peric, 6-8, SF, KK Split 1985 Croatia Second round pick? Good athlete who is still coming into his own as a basketball player  Did not play in the Adriatic League this season  Definitely needs at least another year in Europe, but could use the exposure that declaring for the draft provides 
Kosta Perovic, 7-2, Center, Partizan 1985 Serbia & Montenegro Undrafted? DraftExpress has been told that Partizan needs Perovic to be drafted this year to relieve them of his 500,000$ salary next year as well as help them financially with buyout money for their budget  Unfortunately this is happening about 3 years too late as weve seen little to no improvement from Perovic over that span 
Georgios Printezis, 6-9, PF, Olympiakos 1985 Greece Undrafted Greek power forward played 9 minutes and scored 4 points per game playing for a Euroleague team, and is declaring in hopes of getting his name out before he becomes automatically eligible next year 
Milovan Rakovic, 6-10, PF, Atlas 1985 Serbia & Montenegro ??? American agent Marc Cornstein told us Rakovic will be putting his name in the draft  Still an unknown player, puts up nice numbers on occasion in the fairly weak Serbian YUBA league 
Alexandr Rindin, 7-5, Center, Gala Baku 1985 Azerbaijan Undrafted Huge body, complete unknown  5 points, 5 rebounds per game in FIBA Europe Cup 
Sergio Rodríguez, 6-3, PG, Estudiantes 1986 Spain First round pick Rodríguezs agent in the States told DraftExpress exclusively hell be in the draft, likely for good if he gets a commitment in the 1st round  A disappointing start to his season both in Spain and the ULEB cup made this European prodigy point guard fall on most teams draft boards, but Rodríguez picked things up substantially towards the end of the year and is now playing terrific basketball  Weak NCAA PG crop could put him in the lottery with good workouts 
Dusan Sakota, 6-10, SF/PF, Panathinaikos 1986 Greece Undrafted Fairly unathletic perimeter oriented big man was in the draft last year already  Plays for one of the best teams in Europe and rarely sees the floor for meaningful minutes 
Renaldas Seibutis 6-5, SG, Olympiakos 1985 Lithuania Undrafted One of the most productive players in Europe in his age group considering the level he plays at  Important cog on an excellent team, but lacks athleticism and isnt as good of a shooter as you would hope at this point in his career 
Saer Sene, 7-0, Center, Pepinster 1986? Senegal First round pick? Freakishly long and athletic African prospect who played extremely well at the Nike Hoop Summit  Many question his age and lack of productivity in the very average Belgian league A player teams will want to look at closely 
Sidiki Sidibe, 7-1, Center, Levallois 1985 France ??? 7-1, 265 pound volleyball player and former Kansas State commit will be in this years draft according to his American agent  Too raw to get any playing time whatsoever in French 2nd division 
Tiago Splitter, 7-0, PF/C, Tau Vitoria 1985 Brazil Lottery pick Splitters American agent Herb Rudoy told DraftExpress exclusively hes entering the draft Splitter is having a terrific season in both the ACB Spanish League and the Euroleague, but lack of buyout in his contract means he might not be able to stay in  CBA rules allow him to withdraw and become automatically eligible next season  Tau Vitorias president was quoted saying Splitter will be back in Spain next season 
Sun Yue, 6-9, PG/SF, Aoshen 1985 China Second round pick? Super talented tall point guard with decent athleticism and nice defensive skills  Lacks strength and outside shooting ability  Level of competition is mediocre in American semi-pro ABA league, which makes him an intriguing candidate for Orlando pre-draft camp 
Ali Traore, 6-9, PF, Roanne 1985 France ??? Puts up nice numbers in France  Will participate at the Reebok Eurocamp in Treviso 
Ejike Ugboaja, 6-8, PF, Union Bank Lagos 1985 Nigeria Undrafted Plays for Nigerian National Team 
Goran Dragic, 6-4, PG, Geoplin Slovan 1986 Agent initially notified us that Dragic will be entering the draft, but in the end decided to keep him out  His buyout was always a question mark 
Leigh Enobakhare, 6-10, Center, Oostende 1986 Agent Ugo Udezue from BDA Sports Management told us that Enobakhare will be entering the draft  In the end he must have heard that he is not considered a prospect at all, and decided to keep him out of the draft 
Cartier Martin, 6-8, SF/PF, Kansas State Junior Martin pondered entering his name in the draft, especially after the firing of Kansas State coach Jim Wooldridge 
Nick Young, 6-6, SG, USC Sophomore Young told the LA Daily News in February that hes staying at USC for another year 
D J  Strawberry, 6-5, SG/SF, Maryland Junior Strawberry initially intended to test the waters, but eventually ended up not doing so once he found out that his chances of being drafted are almost non-existent 
Al Thornton, 6-7, SF/PF, Florida State Sophomore Implied earlier on in the year that he might put his name in, but sources recently told us it appears that he will return for his senior year  Tallahassee media backs this up 
Marcus Williams (AZ), 6-8, SG/SF, Arizona Freshman After initially appearing to be gone after numerous definitive reports, Williams surprised everyone and thrilled Arizona fans by announcing in a press conference hell be returning for his sophomore year 
Josh McRoberts, 6-11, PF, Duke Freshman After being upset by LSU in the Sweet Sixteen, McRoberts was quoted saying Ill be at Duke next year   Duke issued a press release a month later confirming this 
Yi Jianlian, 7-0, PF, Guangdong 1987? International Jianlian announced in a press conference that hell be staying in China  A CBA official was also quoted on this matter, sounding as if they were the main factor for him staying put 
Acie Law, 6-3, PG, Texas A&M Junior After a fantastic showing in the NCAA tournament, Law helped his NBA draft stock considerably but will return for his senior year where A&M is expected to make a run at possibly winning the Big 12 
Joakim Noah, 6-11, PF/C, Florida Sophomore Huge 2nd half regular of the regular season and NCAA tournament boosted his stock into as high as the top 5  Noah came out and said afterwards hes staying regardless 
Al Horford, 6-9, PF, Florida Sophomore Horford indicated all season long that hes staying at least one more year, but playing extremely well in winning the national championship gave him a realistic chance at being a lottery pick  Regardless, Horford announced he'll return 
Corey Brewer, 6-8, SF, Florida Sophomore Brewer indicated all season long that hes staying at least one more year, but a terrific performance in the NCAA tournament gave him a realistic chance at being a top 20 pick  Regardless, Brewer announced he'll return 
Glen Davis, 6-8, Center, LSU Sophomore Davis announced hell be returning to LSU immediately after an absolutely horrendous showing in the Final Four which exposed all of his glaring weaknesses  Made it official as an LSU press conference alongside Tyrus Thomas 
Jason Smith, 7-0, PF/C, Colorado State Sophomore Smith announced that hes returning for his junior year, stating that "a little further down the road, it [the NBA] might be in my plans  I'm continuing to concentrate on my academics and see how I can help CSU as much as possible "
Jermareo Davidson, 6-10, PF, Alabama Junior > After burning his lone draft card a year early last June, Davidson considered entering the draft again, but eventually made the right decision in announcing hell be returning for his senior year 
Richard Hendrix, 6-8, PF, Alabama Freshman Told Alabama media after NCAA tournament loss that hell be back in Tuscaloosa next year 
Ja'Vance Coleman, 6-3, SG, Fresno State Junior Testing the waters according to the Fresno Bee  Whoops, no hes not 
Sean Singletary, 5-11, PG, Virginia Sophomore Singletary told The Daily Progress in early February that hes returning 



ground_truth: 62.

prompt_front: Now, answer the following question based on the text below, only give me the answer and do not output any other words.

Question: Where can users go for troubleshooting and support?

Read the following text and answer briefly.

Context 3: 'Quectel_QuecPython_BC25 开发板使用说明 版本：Quectel_QuecPython_BC25 开发板使用说明_V1 1日期：2021-11-30 状态：临时文件
Quectel_QuecPython_BC25 开发板使用说明一、基本概述BC25_QuecPython_EVB_V1 1 开发板（本文简称“V1 1 开发板”）是专门针对 BC25 制造，是一款小巧便携的“口袋型”开发板。体型虽小，但是功能丰富，拥 有 SIM 卡座、板载天线、磁开关、LED 等元件。开发者仅需一条 USB Type-C 数据线即可轻松玩转开发板。二、开发板资源Quectel 移远 BC25 通信模组NANO SIM 自弹卡座USB Type-C 数据接口开机按键，唤醒按键磁开关单色灯GPIO 排针上海市闵行区田林路 1016 号科技绿洲 3 期（B 区）5 号楼 200233 邮箱: info@quectel com 网址: www quectel com 1 / 6
三、开发板介绍Quectel_QuecPython_BC25 开发板使用说明开发板是为方便开发者使用 QuecPython，而设计的一款基于 BC25 通信模块 的开发板，其上集成了开发常用的配置，可以满足开发者的开发需求。V1 1 开发板正面接口V1 1 开发板配置开发板配备了多种外设。明细如下：序 号名称型号是否支持接口类 型1磁开关KTH1601SL-ST3是GPIO2LED 灯S3528UG6W9TLC2G- 是GPIOTJ- 34微动按键GPIOA5--------是是---------上海市闵行区田林路 1016 号科技绿洲 3 期（B 区）5 号楼 200233 邮箱: info@quectel com 网址: www quectel com 2 / 6
Quectel_QuecPython_BC25 开发板使用说明四、功能详解4 1 磁开关开发板集成了一个磁开关。使用磁铁靠近，可使磁开关输出引脚变为低电平， 默认为高电平。4 2 LED 灯开发板集成了一颗高亮度灯珠，可以用来做显著指示灯。上海市闵行区田林路 1016 号科技绿洲 3 期（B 区）5 号楼 200233 邮箱: info@quectel com 网址: www quectel com 3 / 6
4 3 按键开发板集成了 2 个微动按键，其功能是 S1 为开机键，S2 为睡眠唤醒按键。Quectel_QuecPython_BC25 开发板使用说明五、调试步骤1 拿到开发板 V1 1 先插上 USB 安装串口驱动，在官方 QQ 群文件搜 CP210 或者自 行百度下载 CP210x 的串口芯片驱动进行安装。2 使用串口工具（例如 QCOM_V1 6）连接 BC25 的主串口（硬件 17、18 脚）。V1 1 选择 Enhanced COM 口，波特率选择 9600,打开串口，按下 PWK 键约一秒松开进 行开机，串口工具收到消息则代表开机成 功，然后按下 EINT 键串口显示 +QATWAKEUP 表示模组唤醒了。3 从 https://python quectel com/download 下载 BC25QuecPython 版本固件， 使用 Qflash（群文件下载）选择 BC25 的调试串口（硬件 38、39 脚），波特率选 择 921600，选择 lod 后缀的固件，按下 EINT 键串口工具显示模组已经唤醒串口 工具发 AT+QSCLK=0 可关闭睡眠（不会发 AT 则多按几次 EINT 键），点击 Start 开 始下载固件,下载进度条开始下载，等待下载完成。关闭以上所有工具，并给板 子断电重新上电。4 从 https://python quectel com/download 下载 QPYCOM 工具，直接解压运行 工具，选择主串口（同第 2 步），选择 57600 波特率，打开串口。再按 PWK 按键 进行开机，会看到 QPYCOM 有打印 mount Type "help()" for more information 然后就可以进行 QuecPython 的交互调 试了。上海市闵行区田林路 1016 号科技绿洲 3 期（B 区）5 号楼 200233 邮箱: info@quectel com 网址: www quectel com 4 / 6
六、常见问题解决Quectel_QuecPython_BC25 开发板使用说明Q：模块的固件在哪？A：请登录 QuecPython 网站下载：http://python quectel com/downloadQ：哪里有开发板和其他常用资料？A：请登录 QuecPython 网站下载：http://python quectel com/downloadP S  如果您遇到任何问题，请参照本官网在线文档进行解决或访问 QuecPython 社区进行搜索、交流、提问：QuecPython 社区或者联系我们的在线支持：QQ 群 445121768获取 QuecPython 开发固件及加入官方交流群官网主页：https://python quectel com官网文件下载（各类资料、工具）：https://python quectel com/download官网 wiki（常用于视频教程、手把手教程下载、API 库）：https://python quectel com/wiki/#/官网文档中心(拥有从入门到精通的各种文档介绍、必看)：https://python quectel com/doc/工单系统：https://workorder quectel com/QuecPython 社区：https://forumschinese quectel com/c/function-subjects/quectpython/43QuecPython 官方 QQ 开发交流群：445121768微信公众号：QuecPython移远 OTA 升级平台： https://cloudota quectel com/移远 IoT 管理平台：https://python quectel com/doc/doc/Advanced_development/zh/QuecPython Cloud/QuecCloud html上海市闵行区田林路 1016 号科技绿洲 3 期（B 区）5 号楼 200233 邮箱: info@quectel com 网址: www quectel com 5 / 6
附录 1 V1 1 开发板丝印图Quectel_QuecPython_BC25 开发板使用说明附录 2 V1 1 开发板原理图上海市闵行区田林路 1016 号科技绿洲 3 期（B 区）5 号楼 200233 邮箱: info@quectel com 网址: www quectel com 6 / 6
PIU101 PIU102 PIU103 PIU104 PIU105 PIU106 PIU107 PIU108 COR9 PIR902 PIR901 PIU109 PIU1010 PIU1011 PIU1012 PIU1013 PIU1044 PIU1043 PIU1042 PIU1041 PIU1040 PIU1039 PIU1038 PIU1037 PIU1036 COU1A PIU1014 PIU1015 PIU1016 PIU1017 PIU1018 PIU1019 PIU1020 PIU1021 PIU1022 PIU1035 PIU1034 PIU1033 PIU1032 PIU1031 PIU1030 PIU1029 PIU1028 PIU1027 PIU1026 PIU1025 PIU1024 PIU1023 COJ1 PIJ101 COC1 PIC101 PIC102 COC2 PIC201 PIC202 PIC602 COC6 PIC601 COR22 PIR2201 PIR2301 COR23 COR24 PIR2401 PIR2501 COR25 COR14 PIR1401 PIR1601 COR16 PIR2202 PIR2302 PIR2402 PIR2502 PIR1402 PIR1602 COC14 PIC1402 PIC1401 COR33 PIR3301 PIR3302 COU2 PIU201 PIU202 PIU203 PIR3002 COR30 COD6 PIR3001 PID601 PID602 COR31 PIR3102 PIR3101 PIQ201 PIQ203 COQ2 COR32 PIQ202 PIR3201 PIR3202 COR1 COD1 PIR102 PIR101 PID101 PID102 PIQ103 COQ1 PIQ102 COR13 PIR1302 PIR1301 PIQ101 PIR1501 COR15 PIR1502 PIR302 COR3 PIR301 PIR402 COR4 PIR401 PIU1045 PIU1046 PIU1047 PIU1048 PIU1049 PIU1050 PIU1051 PIU1052 PIU1053 COR19 PIR1902 PIR1901 COR20 PIR2002 PIR2001 PIU1072 PIU1071 PIU1070 PIU1069 PIU1068 COU1B PIU1054 PIU1055 PIU1056 PIU1057 PIU1058 PIU1067 PIU1066 PIU1065 PIU1064 PIU1063 PIU1062 PIU1061 PIU1060 PIU1059 PIU1073 PIU1074 PIU1075 PIU1076 PIU1077 PIU1078 PIU1079 PIU1080 COU1C PIU1088 PIU1087 PIU1086 PIU1085 PIU1084 PIU1083 PIU1082 PIU1081 PIU1089 PIU1090 PIU1091 COU1D PIU1094 PIU1093 PIU1092 COM2 COM1 1122334455667788DDCCBBAATitleNumberRevisionSizeA3Date:2021/11/1Sheet ofFile:E:\\\\  \\1 BC25 SchDocDrawn By:1J1ADCR44 7KR34 7KADC_INGNDQUECTEL_LOGOQuecPythonGNDC1100uF 6 3VGNDAUX_TXD_1V8AUX_RXD_1V8GNDUSIM1_VDDRESETNETLIGHTM_RXD_1V8M_TXD_1V8PIN19PIN20VDD_EXTPIN23PIN22PIN21R234 7KR224 7KVDD_EXTR254 7KR244 7KPIN20PIN21PIN23PIN22PIN25PIN30PIN31PIN32PIN33GNDR14 7K312Q1D1蓝 LEDNETR130RR15NCNETLIGHTC61uFGNDGND1RESERVED2MIC_P3MIC_N4SPK_P5SPK_N6PWRKEY7RESERVED8RESERVED9GND10USIM_DATA11USIM_RST12USIM_CLK13USIM_VDD14RESET_N15NET_STATUS16MAIN_RXD17MAIN_TXD18MAIN_DTR19MAIN_RI20MAIN_DCD21MAIN_CTS22MAIN_RTS23VDD_EXT24STATUS25RESERVED26GND27AUX_RXD28AUX_TXD29PCM_CLK30PCM_SYNC31PCM_DIN32PCM_DOUT33GND34ANT_MAIN35GND36GND37DBG_RXD38DBG_TXD39GND40GND41VBAT42VBAT43RESERVED44U1ABC25/EC800NGND45GND46GND47GND48RESERVED49RESERVED50RESERVED51RESERVED52RESERVED53RESERVED54RESERVED55RESERVED56RESERVED57RESERVED58USB_DP59USB_DM60USB_VBUS61RESERVED62RESERVED63RESERVED64RESERVED65I2C_SDA66I2C_SCL67RESERVED68RESERVED69GND70GND71GND72U1BEC800NGND73RESERVED74RESERVED75RESERVED76RESERVED77RESERVED78USIM_DET79RESERVED80RESERVED81USB_BOOT82RESERVED83RESERVED84RESERVED85RESERVED86RESERVED87GND88U1CEC800NGND89GND90GND91GND92GND93GND94U1DEC800NGNDGNDUSIM_DETUSB_BOOTGNDVBUSDM_EC800NDP_EC800NGNDGNDPIN3POWRKEYUSIM1_CLKUSIM1_RSTUSIM1_DATAGNDGNDD_RXD_1V8D_TXD_1V8C2100uF 6 3V+3 8VR90RADCI2C_SCL_EC800NI2C_SDA_EC800NR164 7KR144 7KI2C_SDA_EC800NI2C_SCL_EC800N+3 8VPIN4PIN5PIN6R190RR200RDM_EC800NDP_EC800NUSB_DMUSB_DP+3 8VGNDR304 7K312Q2D6翠绿灯珠NETR310RR32NCPIN30+3 8VGND3OUTPUT2VCC1U2KTH1601SL-ST3VCC_1V8C141uFGNDGNDR3310KVCC_1V8PIN31磁性开关灯珠EC800N焊接R19、R20电源部分请参考官方设计BC25不焊接
COC9 PIC902 PIC901 COU3 PIU301 PIU302 PIU303 PIU306 PIU305 PIU304 COR7 PIR702 PIR701 COL1 PIL101 PIL102 PIC701 PIC702 COC7 COD2 PID202 PID201 COC10 PIC1001 PIC1002 PIC1201 PIC1202 COC12 COR8 PIR802 PIR801 PID501 PID502 COD5 COU6 PIU601 PIU602 PIU603 PIU605 PIU604 PIC1102 COC11 PIC1101 PIC802 COC8 PIC801 COR21 PIR2101 PIR2102 COUSBC1 PIUSBC100 PIUSBC10A12 PIUSBC10A9 PIUSBC10A8 PIUSBC10A7 PIUSBC10A6 PIUSBC10A5 PIUSBC10A4 PIUSBC10A1 PIUSBC10B1 PIUSBC10B4 PIUSBC10B5 PIUSBC10B6 PIUSBC10B7 PIUSBC10B8 PIUSBC10B9 PIUSBC10B12 COR10 PIR1002 PIR1001 COR11 PIC1301 PIC1302 COC13 PIR1101 PIR1102 COD4 PID401 PID402 COD3 PID301 PID302 COD7 PID701 PID702 11223344DDCCBBAATitleNumberRevisionSizeA4Date:2021/11/1Sheet ofFile:E:\\\\  \\2 POWER SchDocDrawn By:type-CDCDCGNDGNDB1VBUSB4CC2B5DP2B6DN2B7SBU2B8VBUSB9GNDB1200000000GNDA1VBUSA4CC1A5DP1A6DN1A7SBU1A8VBUSA9GNDA12USBC1USB3 1C16PFSMTGNDGNDUSB_DMUSB_DMUSB_DPUSB_DPVBUSVBUSVBUSVBUSD3ESD9L5 0ST5GD4ESD9L5 0ST5GD2SMBJ6 5CAGND1SW2VIN3VFB4EN5VBST6U3TPS563201DDCRGND2 2uHL1WPN4020H2R2MTC90 1uFR710KC120 1uFGNDGND+5V+3 8V+5VR1110KR1040 2KC130 1uFGND+3 8VD54 7KR8GND+3 8VC722uF 10VC1022uF 10VVCC_1V8C84 7uFR2110KVIN1GND2EN3NC4VOUT5U6ME6212C18M5GGNDGNDC114 7uFGND+5VD7SS34VBUS+5V
COC3 PIC301 PIC302 COCARD1 PICARD10C1 PICARD10C2 PICARD10C3 PICARD108 PICARD109 PICARD1010 PICARD1011 PICARD10C5 PICARD10C6 PICARD10C7 PICARD10CD PIR1202 COR12 PIR1201 PIU501 PIU503 PIU504 PIU505 PIU506 COU5 PIU502 11223344DDCCBBAATitleNumberRevisionSizeA4Date:2021/11/1Sheet ofFile:E:\\\\  \\4 SIM-CARD SchDocDrawn By:123456U5USIM1_VDDUSIM1_RSTUSIM1_CLKUSIM1_DATAGND10KR12USIMGNDVCCC1RSTC2CLKC3I/OC7VPPC6GNDC5CDCDEP8EP9EP10EP11CARD1SMN-303GNDC30 1uFUSIM_DET
COJ5 PIJ501 PIJ502 PIJ503 PIJ504 PIJ505 PIJ506 PIJ507 PIJ508 PIJ509 PIJ5010 PIJ5011 PIJ5012 PIJ5013 PIJ5014 PIJ5015 COJ6 PIJ601 PIJ602 PIJ603 PIJ604 PIJ605 PIJ606 PIJ607 PIJ608 PIJ609 PIJ6010 PIJ6011 PIJ6012 PIJ6013 PIJ6014 PIJ6015 COU4 PIU409 PIR501 PIR502 COR5 COS1 PIS101 PIS102 COR17 COS2 PIR1702 PIR1701 PIS201 PIS202 COR18 PIR1802 PIR1801 COR2 PIR201 PIR202 PIC402 COC4 PIC401 PIC502 COC5 PIC501 PIR602 COR6 PIU405 PIR601 PIU406 PIC1702 PIC1701 COC17 PIU407 PIU402 PIU408 PIU403 PIU404 PIU401 PIU4024 PIU4023 PIU4022 PIU4021 PIU4020 PIU4019 PIU4018 PIU4017 PIU4016 PIU4015 PIU4014 PIU4013 PIU4012 PIU4011 PIU4010 PIU400 COR26 COR27 PIR2602 PIR2702 PIR2601 PIR2701 COR28 COR29 PIR2802 PIR2902 PIR2801 PIR2901 11223344DDCCBBAATitleNumberRevisionSizeA4Date:2021/11/1Sheet ofFile:E:\\\\  \\6 GPIO+UART SchDocDrawn By:GPIOAUX_RXD_1V8AUX_TXD_1V8GNDD_TXD_1V8D_RXD_1V8S1S2GNDVDD_EXTPOWRKEYPIN19VBUSRI_SCI1GND2D+3D-4VIO5VDD6REGIN7VBUS8-RST9CTS_ECI10RTS_ECI11RXD_ECI12TXD_ECI13GPIO 1_ECI14GPIO 0_ECI15NC16RI_ECI17CTS_SCI18RTS_SCI19RXD_SCI20TXD_SCI21GPIO 2_SCI22GPIO 1_SCI23GPIO 0_SCI24GND0U4CP2105GND1uFC17R5NC1uFC4C50 1uFGNDGNDR6NCR20RADC_INM_TXD_1V8M_RXD_1V8PIN19PIN25PIN33PIN30PIN31PIN32USB_DMUSB_DPM_RXD_1V8M_TXD_1V8R260RR270RR280RR290RD_RXD_1V8D_TXD_1V8PIN3PIN4PIN5PIN6PIN20PIN21PIN22PIN23123456789101112131415J5Header 15123456789101112131415J6Header 15R170RR180RUSB_BOOTI2C_SCL_EC800NI2C_SDA_EC800N+3 8VRESETGNDVCC_1V8VCC_1V8+5VEC800N不焊接CP2105
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ground_truth: Online documentation, QuecPython community, online support: QQ group 445121768.