Fig. 5. Additive effect of TLN468 and gentamicin. HeLa cells were treated with gentamicin, TLN468 or both drugs for 24 h. Stop codon readthrough (R213X) was then quantified with the dual reporter system. The values for the untreated cells were set to 1 and fold changes were calculated relative to this value. At least 6 independent measurements were performed for each treatment.