Figure 4 SI-induced RPE and ONL degeneration in sclerochoroid/RPE/retina whole mounts stained with Alexa 488-conjugated phalloidin (green) and RPE65 (red). SI (40 mg/kg, i.p.)-induced degeneration in retinal pigment epithelium (A) and photoreceptor (B) layers of BALB/C mice. RPE65 expression (arrow heads) was observed at the bordered region of RPE damage and ONL (PR) layer. Scale bars: 50 μm. SI, sodium iodate; RPE, retina pigment epithelium; PR, photoreceptor; ONL, outer nuclear layer.