Fig. 1. ak mice show both gross and fine motor functional deficits. Four- to six-month-old male rd1 and ak mice were subjected to a battery of motor function tests: (A) challenging beam test; (B) cylinder test; (C) rotarod test, (D) adhesive removal test; (E) grip strength test; and (F) nest building test. * p  < 0.05; ** p  < 0.01; *** p  < 0.001 Mean ± S.E.M,  n  = 7–10 for each group.