Figure 8 Schematic summary of ocular degeneration in SI-induced retina degeneration. (A) Normal retina layers. (B) RPE degeneration starts before the end of Day 1. (C) RPE loss and RPE intraretinal migration at Day 1. (D) Progressing PR degeneration following RPE degeneration. (E) ONL rosettes formation and disrupted subretinal space with mingled cells from neighboring layers. OPL, outer plexiform layer; ONL, outer nuclear layer; IS, inner segment; OS, outer segment; PR, photoreceptor; RPE, retinal pigment epithelium; BrM, Bruch’s membrane; Ch, choroid; SI, sodium iodate.