Figure 7 Quantification of SI-induced ONL rosette formation in sclerochoroid/RPE/retina whole mounts. SI (20, 50 mg/kg, i.p.)-induced retina degeneration in BALB/C mice. (A) The tiled and projected confocal images of Normal, Week 1 and Week 3, post SI injection. Boxed areas are magnified in inserts. (B) A graph of total areas of rosettes in the defined retina area at Week 1 and Week 3 (see details in  Figure S1 ). (C) A graph of the area ratio of occupied rosettes in retinal regions. Scale bar, 500 μm. SI, sodium iodate; ONL, outer nuclear layer; RPE, retina pigment epithelium.