Figure 5 SI-induced ocular damage from choroid toward ONL in sclerochoroid/RPE/retina whole mounts stained with Alexa 488-conjugated phalloidin. SI (50 mg/kg, i.p.)-induced retina degeneration in BALB/C mice. Images were arranged at a 2 μm interval with projected images (the most left column). The separate distinct layers of choroid (A,B), RPE (C), PR segment (D) in normal are blended in SI retinas. PR nuclei (arrows) and RPE nuclei (arrow heads) in SI-damaged retinas. Choroidal vasculatures (asterisks) in normal and SI-damaged retinas. Scale bar: 50 μm. RPE, retina pigment epithelium; SI, sodium iodate; ONL, outer nuclear layer; PR, photoreceptor.