
 Fig . 4. p38 inhibitor impairs BPXV genome and protein synthesis. Confluent monolayers of Vero cells were infected with BPXV at an MOI of 5. The inhibitor or DMSO was applied at 3 hpi and the cells were scrapped at 24 hpi to examine the levels of viral proteins ( A1 ). The blots were quantified by densitometry (ImageJ) and the data are presented as mean with SD. Histogram  A2  shows band intensities of BPXV protein in inhibitor-treated and untreated cells. The levels of viral DNA is also shown ( B ). Pair-wise statistical comparisons were performed using Student's  t -test. *** =  P  < 0.001. Values are means ± SD and representative of the result of at least tree-independent experiments.