涂文清

江西省科学院流域生态研究所副所长
涂文清，博士，男，1987年生，江西南昌人，江西农业大学校“第四类”高层次引进人才，副研究员（校聘教授），加拿大渥太华大学访问学者（合作导师：Laurie Chan院士）。
现任江西省科学院流域生态研究所副所长。
教育经历
2009.09-2014.06   浙江工业大学，环境科学与工程专业，博士 （硕博联读）
2006.09-2009.06   福建师范大学，环境科学专业，学士 （提前一年本科毕业）
工作经历
2022.01-至今         江西农业大学国土资源与环境学院，副研究员/校聘教授
2018.01-2021.12   江西省科学院微生物研究所，副所长、副研究员
2018.02-2019.02   加拿大渥太华大学，访问学者（合作导师：Laurie Chan 院士）
2014.06-2017.12   江西省科学院鄱阳湖研究中心，助理研究员
中国人民政治协商会议江西省第十三届委员会委员、常务委员。
研究方向
主要从事环境化学与环境毒理学研究，着重以“污染物暴露-效应评价-毒性机制”为主线，围绕持久性有机污染物（POPs）的生态效应与健康风险开展一系列相关工作。
主要成就
以第一完成人获江西省自然科学二等奖1项，入选江西省“双千计划”人才工程、江西省百千万人才工程、江西省百人远航工程、江西英才工程，荣获省直机关青年五四奖章等荣誉。现主持或完成国家自然科学基金项目4项、国家外专局项目1项和省厅级项目7项，已发表SCI收录论文40余篇，其中以第一作者或通讯作者身份在Environmental Science & Technology、Journal of Hazardous Materials、Environment International、Science of the Total Environment等环境领域知名期刊上发表JCR一区SCI论文23篇（其中IF>10的12篇），授权国家发明专利4项，参与出版专著1部。
奖励与荣誉
1. 获得2021年度江西省自然科学二等奖（第一完成人）
2. 入选江西省“双千计划”人才工程（2020年度）
3. 入选江西省百千万人才工程（2019年度）
4. 入选江西省百人远航工程（2018年度）
5. 入选“江西英才”工程（2020年度）
6. 荣获江西省直机关青年五四奖章（2021年度）
社会任职
担任江西省生态环境厅应急专家、江西省高企认定评审专家、农工党江西省委会委员、江西省同心智库专家、中国青年科技工作者协会会员、江西省青年科技工作者协会理事、农工党中央长江生态环境保护民主监督专项工作组专家、国家自然科学基金委及多个省市基金委项目函评专家，以及Environmental Science & Technology、Journal of Hazardous Materials、Environment International、Chemical Engineering Journal, Environmental Pollution、Science of the Total Environment等环境领域20余种国际权威学术期刊审稿专家。
科研项目
1. 国家自然科学基金，新型PFOS替代品OBS干扰多巴胺稳态诱导斑马鱼认知功能障碍的分子机制（42267039），2023.01-2026.12，主持（在研）
2. 国家自然科学基金，新型全氟化合物替代品干扰斑马鱼摄食和能量代谢的分子机制研究（42007377），2021.01-2023.12，主持（在研）
3. 国家自然科学基金，基于环境浓度下全氟烷基醚磺酸盐慢性暴露对斑马鱼免疫和抗氧化功能的影响及其机理研究（41867064），2019.01-2022.12，主持（在研）
4. 国家自然科学基金，全氟烷基醚磺酸盐对斑马鱼的毒代动力学及甲状腺代际毒性转移机制（21647005），2017.01-2017.12，主持（已结题）
5. 国家外国专家局项目，规模猪场抗生素-重金属复合污染对水生生态系统和人体健康的风险评估（P172022005），2018.02-2019.02，主持（已结题）
6. 江西省“双千计划”科技创新高端人才项目（jxsq2019201086），2020.01-2022.12，主持（在研）
发表论文
1. Aiping Tang, Xinghui Zhang, Rongfu Li,Wenqing Tu, Huiqin Guo, Yanping Zhang, Zongrui Li, Yu Liu*, Bixian Mai. Spatiotemporal distribution, partitioning behavior and flux of per- and polyfluoroalkyl substances in surface water and sediment from Poyang Lake, China.Chemosphere2022, 295:133855.
2. Jing Huang, Qiyu Wang, Shuai Liu*, Hong Lai,Wenqing Tu*. Comparative chronic toxicities of PFOS and its novel alternatives on the immune system associated with intestinal microbiota dysbiosis in adult zebrafish.J Hazard Mater2022, 425: 127950.
3. Su He, Wenjia Zhao, Peibo Li,Wenqing Tu, Kui Hong, Duoduo Zhang, Tongke Zhang, Ganjun Yuan*. Pharmacokinetics of azalomycin F, a natural macrolide produced by streptomycete strains, in rats.Molecules2021, 26: 6464.
4. Caiyun Wang, Cuiyuan Jin,Wenqing Tu, Yuanxiang Jin*. Maternal exposure of mice to sodium p-perfluorous nonenoxybenzene sulfonate causes endocrine disruption in both dams and offspring.Endocr J2021,68: 1165-1177.
5. Jing Huang, Qiyu Wang*, Shuai Liu, Miao Zhang, Yu Liu, Liwei Sun, Yongming Wu,Wenqing Tu*. Crosstalk between histological alterations, oxidative stress and immune aberrations of the emerging PFOS alternative OBS in developing zebrafish.Sci Total Environ2021, 774: 145443.
6. Caiyun Wang, You Weng,Wenqing Tu*, Caiyuan Jin, Yuanxiang Jin*. Maternal exposure to sodium ρ-perfluorous nonenoxybenzene sulfonate during pregnancy and lactation disrupts intestinal barrier and may cause obstacles to the nutrient transport and metabolism in F0 and F1 generations of mice.Sci Total Environ2021, 794: 148775.
7. Jing Huang, Liwei Sun, Jan Alexander Mennigen, Yu Liu, Shuai Liu, Miao Zhang, Qiyu Wang*,Wenqing Tu*. Developmental toxicity of the novel PFOS alternative OBS in developing zebrafish: an emphasis on cilia disruption.J Hazard Mater2021, 409: 124491.
8. Zihong Pan, Wenyu Miao, Caiyun Wang,Wenqing Tu, Cuiyuan Jin, Yuanxiang Jin*. 6:2 Cl-PFESA has the potential to cause liver damage and induce lipid metabolism disorders in female mice through the action of PPAR-γ.Environ Pollut2021, 287: 117329.
9. Shuai Liu, Hong Lai, Qiyu Wang, Rubén Martínez, Miao Zhang, Yu Liu, Jing Huang, Mi Deng,Wenqing Tu*. Immunotoxicity of F-53B, an alternative to PFOS, on zebrafish (Danio rerio) at different early life stages.Sci Total Environ2021, 790: 148165.
10. Yilong Zou, Yongming Wu, Qiyu Wang, Jinbao Wan*, Mi Deng,Wenqing Tu*. Comparison of toxicokinetics and toxic effects of PFOS and its novel alternative OBS in zebrafish larvae.Chemosphere2021, 265, 129116.
11. Huilin Yang, Hong Lai, Jing Huang, Liwei Sun, Jan Alexander Mennigen, Qiyu Wang, Yu Liu, Yuanxiang Jin*,Wenqing Tu*.Polystyrene microplastics decrease F-53B bioaccumulation but induce inflammatory stress in larval zebrafish.Chemosphere2020, 255: 127040.
12. Yu Liu, Xiaojun Luo*, Yanghong Zeng, Qiyu Wang,Wenqing Tu, Chunyan Yang, Bixian Mai. Trophic magnification of short-and medium-chain chlorinated paraffins in terrestrial food webs and their bioamplification in insects and amphibians during metamorphosis.Environ Sci Technol2020, 54: 11282-11291.
13. Yu Liu, Xiaojun Luo*, Yanghong Zeng,Wenqing Tu, Mi Deng, Yongming Wu*, Bixian Mai. Species-specific biomagnification and habitat-dependent trophic transfer of halogenated organic pollutants in insect-dominated food webs from an e-waste recycling site.Environ Int2020, 138: 105674.
14. Xianling Yuan, Jiayan Shen, Xinyue Zhang,Wenqing Tu, Zhengwei Fu, Yuanxiang Jin*. Imidacloprid disrupts the endocrine system by interacting with androgen receptor in male mice.Sci Total Environ2020, 708: 135163.
15. Rubén Martínez,Wenqing Tu, Tyler Eng, Melissa Allaire-Leung, Benjamin Piña, Laia Navarro-Martín, Jan A. Mennigen*. Acute and long-term metabolic consequences of early developmental Bisphenol A exposure in zebrafish (Danio rerio).Chemosphere2020, 256, 127080.
16. Yu Liu, Xiaojun Luo*, Yanghong Zeng, Mi Deng,Wenqing Tu, Yongming Wu*, Bixian Mai. Bioaccumulation and biomagniﬁcation of hexabromocyclododecane (HBCDD) in insect-dominated food webs from a former e-waste recycling site in South China.Chemosphere2020, 240, 124813.
17. Lingyan Ma, Yinhua Ni*, Zhe Wang,Wenqing Tu, Liyang Ni, Fen Zhuge, Aqian Zheng, Luting Hu, Yufeng Zhao, Liujie Zheng Zhengwei Fu. Spermidine improves gut barrier integrity and gut microbiota function in diet-induced obese mice.Gut microbes2020, 12(1), 1832857.
18.Wenqing Tu, Rubén Martínez, Laia Navarro-Martín, Daniel J. Kostyniuk, Christine Hum, Jing Huang, Mi Deng, Yuanxiang Jin, Hing Man Chan, Jan Alexander Mennigen*. Bioconcentration and metabolic effects of emerging PFOS alternatives in developing zebrafish.Environ Sci Technol2019, 53: 13427-13439.
19. Caiyun Wang, Yi Zhang, Mi Deng, Xia Wang,Wenqing Tu*, Zhengwei Fu, Yuanxiang Jin*. Bioaccumulation in the gut and liver causes gut barrier dysfunction and hepatic metabolism disorder in mice after exposure to low doses of OBS.Environ Int2019, 129: 279-290.
20. Zihong Pan, Xianling Yuan,Wenqing Tu*, Zhengwei Fu, Yuanxiang Jin*. Subchronic exposure of environmentally relevant concentrations of F-53B in mice resulted in gut barrier dysfunction and colonic inflammation in a sex-independent manner.Environ Pollut2019, 253: 268-277.
21. Yongming Wu, Mi Deng, Yuanxiang Jin, Xin Liu, Zhaohuan Mai, Hailin You, Xiyan Mu, Xiaoli He, Reem Alharthi, Daniel Joseph Kostyniuk, Chunyan Yang,Wenqing Tu*. Toxicokinetics and toxic effects of a Chinese PFOS alternative F-53B in adult zebrafish.Ecotoxicol Environ Saf2019, 171: 460-466.
22. Yongming Wu, Mi Deng, Yuanxiang Jin, Xiyan Mu, Xiaoli He, Nha-Thi Luu, Chunyan Yang,Wenqing Tu*. Uptake and elimination of emerging polyfluoroalkyl substance F-53B in zebrafish larvae: Response of oxidative stress biomarkers.Chemosphere2019, 215: 182-188.
23. Yongming Wu, Jing Huang, Mi Deng, Yuangxiang Jin*, Huilin Yang, Yu Liu, Qinyan Cao, Jan A. Mennigen,Wenqing Tu*. Acute exposure to environmentally relevant concentrations of Chinese PFOS alternative F-53B induces oxidative stress in early developing zebrafish.Chemosphere2019, 235: 945-951.
24. Xiaoling Yu, Yongming Wu, Mi Deng, Yu Liu, Shuang Wang, Xiaoli He, Melissa Allaire-Leung, Jinbao Wan*, Yilong Zou, Chunyan Yang,Wenqing Tu*. Tetracycline antibiotics as PI3K inhibitors in the Nrf2-mediated regulation of antioxidative stress in zebrafish larvae.Chemosphere2019, 226: 696-703.
25. Yuanxiang Jin, Liang Lu,Wenqing Tu, Ting Luo, Zhengwei Fu*. Impacts of polystyrene microplastic on the gut barrier, microbiota and metabolism of mice.Sci Total Environ2019, 649: 308-317.
26. Zhaohuan Mai*, Shuanglin Gui, Jiaqi Fu, Cheng Jiang, Emily Ortega, Yan Zhao,Wenqing Tu, Willian Mickols*, Bart Van der Bruggen. Activity-derived model for water and salt transport in reverse osmosis membranes: a combination of film theory and electrolyte theory.Desalination2019, 469: 114094.
27. Chao Xu, Lili Niu, Hangqin Guo, Xiaohui Sun, Lihui Chen,Wenqing Tu, Qizhou Dai, Jing Ye, Weiping Liu, Jinsong Liu*. Long-term exposure to the non-steroidal anti-inflammatory drug (NSAID) naproxen causes thyroid disruption in zebrafish at environmentally relevant concentrations.Sci Total Environ2019, 676: 387-395.
28. Chao Xu*, Xiaohui Sun, Lili Niu, Wenjing Yang,Wenqing Tu, Liping Lu, Shuang Song, Weiping Liu. Enantioselective thyroid disruption in zebrafish embryo-larvae via exposure to environmental concentrations of the chloroacetamide herbicide acetochlor.Sci Total Environ2019, 653: 1140-1148.
29. Mi Deng, Yongming Wu, Chao Xu, Yuanxiang Jin, Xiaoli He, Jinbao Wan*, Xiaoling Yu, Hongming Rao,Wenqing Tu*. Multiple approaches to assess the effects of F-53B, a Chinese PFOS alternative, on thyroid endocrine disruption at environmentally relevant concentrations.Sci Total Environ2018, 624: 215-224.
30. Xiyan Mu*, Jia Liu, Ke Yang, Ying Huang, Xuxing Li, Wenbo Yang, Suzhen Qi,Wenqing Tu, Gongming Shen, Yingren Li*. 0# Diesel water-accommodated fraction induced lipid homeostasis alteration in zebrafish embryos.Environ Pollut2018, 242: 952-961.
31. Cuiyuan Jin, Jizhou Xia, Sisheng Wu,Wenqing Tu, Zihong Pan, Zhengwei Fu, Yueyi Wang, Yuanxinag Jin*. Insights into a possible influence on gut microbiota and intestinal barrier function during chronic exposure of mice to Imazalil.Toxicol Sci2018, 162: 113-123.
32.涂文清*, 余晓玲, 邓觅, 何小立, 吴永明, 邹义龙, 陆彬, 杨春燕, 徐超. 环境因素对酰胺类除草剂水生毒性的影响——以鱼类先天性免疫毒性为例.湖南科技大学学报 (自然科学版)2018, 33: 26-31.
33.Wenqing Tu, Chao Xu*, Yuangxiang Jin, Bin Lu, Chunmian Lin, Yongming Wu, Weiping Liu. Permethrin is a potential thyroid-disrupting chemical:In vivoandin silicoenvidence.Aquat Toxicol2016, 175: 39-46.
34.Wenqing Tu, Chao Xu*, Bin Lu, Chunmian Lin, Yongming Wu, Weiping Liu. Acute exposure to synthetic pyrethroids causes bioconcentration and disruption of the hypothalamus-pituitary-thyroid axis in zebrafish embryos.Sci Total Environ2016, 542: 876-885.
35. Chao Xu,Wenqing Tu*, Mi Deng,Yuangxiang Jin, Bin Lu, Chaonan Zhang, Chunmian Lin, Yongming Wu, Weiping Liu. Stereoselective induction of developmental toxicity and immunotoxicity by acetochlor in the early life stage of zebrafish.Chemosphere2016, 164: 618-626.
36.涂文清, 周斌彬, 吴永明, 刘丽贞, 游海林, 杨春燕. 新型溴代阻燃剂代谢产物 TBBA 和 TBMEHP 抗雌激素活性的分子机理.江西科学2015, 33, 804-806.
37.Wenqing Tu, Bin Lu, Lili Niu, Chao Xu*, Chunmian Lin, Weiping Liu. Dynamics of uptake and elimination of pyrethroid insecticides in zebrafish (Danio rerio) eleutheroembryos.Ecotoxicol Environ Saf2014, 107: 186-191.
38.Wenqing Tu, Lili Niu, Weiping Liu, Chao Xu*. Embryonic exposure to butachlor in zebrafish (Danio rerio): endocrine disruption, developmental toxicity and immunotoxicity.Ecotoxicol Environ Saf2013, 89: 189-195.
39. Jianqiang Sun, Jinsong Liu,Wenqing Tu, Chao Xu*. Separation and aquatic toxicity of enantiomers of the organophosphorus insecticide O-ethyl O-4-nitrophenyl phenylphosphonothioate (EPN).Chemosphere2010, 81: 1308-1313.
40. Chao Xu,Wenqing Tu, Chun Lou, Yingying Hong, Meirong Zhao*. Enantioselective separation and zebrafish embryo toxicity of insecticide beta-cypermethrin.J Environ Sci2010, 22: 738-43.
发明专利
1. 一种基于Fenton-超声波耦合化废水处理体系，发明人：涂文清，黄晶，吴永明，王启宇，邓觅（ZL201911298419.9）2. 江西省高新技术企业认定评审专家（2020-至今）
2. 一种适用于水生模式生物的长期暴露实验系统，发明人：涂文清，黄晶，邓觅，吴永明（ZL201910996910.2）
3. 一种污水过滤环保装置，发明人：涂文清，吴永明，游海林，刘丽贞，辛在军，黄晶（ZL201710143446.3）
4. 一种便于清洗的空气净化器，发明人：涂文清，吴永明，张杰，姚忠，黄晶，杨春燕（ZL201710143500.4）