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Office Memo. indum UNITED ST..ES GOVERNMENT

DATE: 12 Sopteaber 1355

FROM: Chief,offico

SUBJECT:

4/8, 211,8

1. In rosponse tci xe wired today as follows; fcontacted ? Soptember. Haterial discussed at thi neetin:; in -April 1955 wás mcncaline enelogues, not LSD which has no derivativos. is doing the investigating and has studied over 100 compounds of mescaline."

2. had this additional information which he said he was surn vou were avare of: cither instigated er are associated with in this prorram, which has a grant fom the : The productsbeing used have alr boen synthosizei. They have studied the cffects of these drugs and have been working on the relationship betreen tho struoture of phenet.ylamines nnd their effects on tho enzyme activity of the brain with the aim of finding a mescaline aualogue which will antazcnize thn acticn of moscnline. also stated that n pharmacologist at the is also investigating mescaline anaiogues.

3.informed me that his investigation of liven Cerymbosa or Piule is goinr forwari, unò he expects to hsve a report on this in late Cctober. He is most enthusiastic about: this research.

4. hen,.was hore in April 1955, he tolu fthat ho folt' sure he could Cet n suaply of mushroon nikoloids from Amanita Fantherina. If you have a surply available, would you please send it on to this office?

5. Have an steps been taken to ret a clearanceon/ feels that it vould be,most helnful in his investigations to have "on the toan". roturnsd to the in July 1955 alter a two-or-thrcc-ycar periorl of loan to the Flease lct mo know if you do not hnvc the necessary bio-Fraphical material for a naune check, and I will forward it to yon.

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A/B,I,211,9

àttaclext heretith in a surjes of oueubtens wbteh i have aneercled fer constderation by ou Oricnds ptPoe : an nci coia to pt a elanolfiettion stap en thn r.ca learán the gucmtes ssi tìa erpirtm tory rorarke, bat 1 thtndi von phenjd hanole ii rs thonihb ii. woro "ceerot" and aawoval with Lho source aot diselosed.

Coma of tho queattona arn conplox anl will. roquire oxtensive reacarch wtilo others an shply eskia for vics and cinions. loaso toll our friends thrt tho quostions conearnding rosnsreh ao roi in fael requcots for vescarch. (At Who prcsend tire, ve canoh finance exicrsivo roooarch alorg tho propoced linzs) Vo are only acokin: the opbions suò vieua of hirhly skinled epeelallate whoto anmtors ma idoaa mrn aiags cxtrerely valuahlo.

woro tho qneulien is tired at oue luosivicual (I bolfovo rout of thea pro pointed dirõetly atI will iudicate aa tho qcsticn. whore tho qucctiona cten fre re previous convorsaciouc, i nay follow wi.th an oxplanatory note.

ta yan knou, uilt nt ia éiaopi eiatet if the queswieaspe uaansaered as 1 ferl cur trlonte there kave ate siy rde a Cansiseraie coutrhimutlon to our verr sni thelr idess au: jcvosoi nezee haveNueen prolltabile to us.

I received tho roturn recoipt for tho sede i en rellhted! they errivod imact. I hopo thn writlen matoriel uili bo naoful for.e? intended stnly. if lyr aro any questitens, vrite an anr will tranufor thon toe .who cbtaina these specirrns throuch his vide not of contacte.

seu montioned a Lrie te vashiactea in the futare pond a Jicaire to reed ry report on theee irt. Dnfortunatels, 1 vill. peebabl: te in fron 1? /eteatr cutoagh 19 ctolar tt1 have jnforrnd ry secrobary,se a, to arka a cepy aveilal lo fer par reedliug shilo hern. Au thld istnrternì Uceurity reporb, I camuet leb you have a copy for your fhles. I teoi you vüll moderslna: ! e.

Feat recarés eai Wanka e oin Tor Lo vay tiina you hve dane for tuia mçecisl cyre of vork.

Sinenrely,

12 Fenterier 1925