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Transmitted herewith are the clinica' raports of tes's conductedduring July and August 1957. The outside temperature was very high with a cànstanily humid atmosphere. Tests were conducted in non-air conditionl buldings end astinated ins.de temperatures ranged fron 9o to loo) degrees F.

: Test Hi

The drug used in this case was sodium amytal intravenously, 57 solution at the rate of 1 cc a minute. The stimulant employed was benzedrinc intravancously at the rate of 1 cc a minute plus 10 mg given orally at the compielion of the technique.

Thz intravenous injection was begun at 133. At 1342, 9.4 cc had been administered. At l345 the Subject was sound aslecp. Il was possibie to arouse him but in order to obtain the exact state desired intravenous benzedrine, as a stimulant, was administered. At l405, he was accessible, but his spcech was quite thick. At that time 1 ec more of benzedrine was given intravenously following which he was in the proper state for the interrogation. The interrogation and other conversation was continued until 144? when the Subjcct was ld to g to sleer, whch he did. At 1453. he was given 2 cc of th: benzedrine solution, follow ng which he became quite wide awake. At l6l5, I benzedrine tablet was given to be taken orally, the dose being 10. mg.

The Subject had amnesia as to his conversations under the influence nf the medication. This test vas regarded as successful.

Test. #2

The drug used in this case was sodium amytal intravenously, 5% solution given at the rate of l cc a minute. The total amount administered was 16 cc or .8 gm. The stimulant was benzedrine, 20 mg, 2-5 cc intravenously. A total of 9 cc was given or 36 mg. The injection was started at 114l. At 1152, after the administration of ll cc of sodium amytal solution, the Subject said his head felt woozy. At ll55, he was nearly asleep but awakencd with a start upon being aroused. From that time on, he was occasionally given 1 cc more of the solution in order to maintain the proper state for the technique. At 1237, he was again asleep but casily aroused and the same at l245.

The desired effect of the mcdication was obrained. The Subject was interrogated under simulated enemy conlitions and he was quite violent upon occasiens during the interrogation as he was convinced that th: interropators were his enemies. At 1259, the stimulant was begun and although he gradually awakened, at 125?, after the adm nistration of 7cc of benzedrine solution, he said thal he st:ll fel'. sleepy. He was given 2cc more ai l303. At 1353, he was awake. At 1404, he was sent to eat and then sleep. He said he still feli a little dizzy.

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Th: Subject had amnesia as to his conversations under lhe influenep of the medication. Ths test was rgurded as successful.

Tesl \$3

The medication administered was sodium amylal intravenously, 57 solution given al the rate of l cc a minute. The stimulants were benzedrine intravencusly and picrotoxin intravenously.

The total amount of sodium amytal administrered was l6 cc or 0.8 gm. Thz amnount of the benzedrine slu jon totaled 5 cc or 23 mg was given and 1.5 cc of picrotoxin.

The medication was begun at 1048. At 1106, after 1l cc had been administered, the Subject complained of blurred vision. At 1ll2, following the administration of 12 cc (total), his eyes seemed heavy. At Ilzl, after the total administration of 16 ce, he was found to be yawning. At il2?, he was asieep but could be fairly easily aroused. At. l2l2, the desired effect of the mpdication was obtained an1 at 1215 successful interrogation was begun. At 1247, the stimulant was begun, that is, benzedrine intravenously. At 1252, a total.of 5 cc had becn administered and although the Subject could be aroused, he still scemed quite sleepy. At 122l, picrotoxin was given, a total of 1.5 cc. At l226, the Subject was awake. However, in the afternoon after having had his lunch. he was visited in his room at 1445 and was found to be slecping coundly.

The Subject had amnes:a as to his conversations under ths influence of ths medication. This test was regarded as successful,

Test d4

The medication in this case was sodium amytal intravenously, 5% solution administered at the rate of l ec a minute. The total amount of sodium amytal was 15 cc or ).75 gm.: The stimulants were picrotoxin intravenously, total 2 cc and benzedrine, 17 mg orally.

The :ntravenous sodium amytal was started at 1524 with 7 cc being given at the rate of i cc a minute and then a few minutes were allowed to elapse to observe the effect followinp which 2 morc ec were given. A waiting period again followed with 3 more ec being given and then again a wailing period followed by 3 more cc and finally 3 cc at l604. The inermitient nature was to kec the atient at the proper uoint for th: interrogution. At 16ln, the administration of 2. 5 cc of picrotoxin hid been completed. The Subject still slept f:llowing this by permission for 5 minutes. He was then awakened. At 1701, 1.5 cc of picrotoxin was admin-Istered andl at 1795. 0.5 cc of picrotoxin. The Subject, at that time, was awake but said that he felt sleepy.: At 1720, 10 mg of oral benzedrine was given.

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The Subject had amucsia as to his conversatlons under the infiuence of the medication. This test wis regarded as successful.

Test 45

The drug used in this case was sodium penthothal. A 2 l/2% solution was given intravenousiy. The first 10 cc was given at the rate of ¿ cc a minute; beyond that, I cc a minute. The stimulant was benzedrine, 10 mg orally. The iotal anmount of sodium pentholhal was 19 ce of the solution which would represent not quile 3.5 gm. of the drug.

The intravenous sodium penthothal was stirted at llou. At ll75, 1) ee had been admnistered. At ll07, the injection was again started and this continued at Illl, 4 more cc having been administered. At that time, the Subject dozed ofl but was easily aroused. At lll7, the injection was again started and this continued after the administration of 1 more cc. This procedure of giving 1 cc 1ntermittently was repeated at 1122, 1l25, 113) and 1134.

The original pian was to give an intravenous stimulant but the needle had become clocged due to a. blood clot therein and it was believed to be inadvisable to have to make another puncture, hence, the stimulant was given orally at l222 (10 mg of benzedrine). At lz35, black coflee was administered. The Subject was then instructed to rest for a half of an hour and then eat his midday meal.

The meriication was eflnctive as to the Jesired results. It is believed thit when this pariicuiar drug, sodium pentothal, is used, the inethod employed in this case is best, that is, after the initial stage of impaired consciousness be produced, it is advisable to give intermittently small amounts of th.: drug in order to maintain the desired state. When using sodium arnytal, however, due to the morc prolonged effect, it is not so neceasary to inter-space minute doses in this way. The advantape of sodium pentothal is that it is much easier to have the man back in his normai state in a comparativuiy short time but it is not certaun that the amnesia will be as definite as in the use of the longer acting drug. In this nrt:culir case, amnnesia for the interrogation was produced. Also sodtum penthothal is sl'ghtly more dangerous than sodium amytal in the more rapid production of respiratory falure.

The Subjeet had amnesia as to his conversations under the influcnce of the medication. This test was regarded as successful.

Test 86

Sodiuin pentothal, intravenously, was used in this case, 2 1/2% solution at the rate of I cc a minute.' The total amount of sodium pentothai was 9.4 cc of the solution, represcnting approximately 0. 24 gm of the drug. The stimulant was intravenous coramine.