[PAGE 2]
It is proposed that the

be provided with funds for

the study and.evaluation of certain persons released by Communist bloc countries. The cost of the work coniemplated in this project is as follows:

Personal-Compensation2720.00

Travel 2000,00

Miscellaneous 100000

Total\$5720.00

[PAGE 3]
MEMORANDUM FOR: THE RECORD

: Projeot-MKULTRA, Subproject /21

1. The aim of this subproject is to provide funds for an increase in the scope of that portion of Subproject 48 which deals with the over-all-returnee interrogation and re= habilitation progran now being carried out by the B Since It ia impossible to estimate-in advance the numcer of subjects to be handled under this program, it will be necessary to enlarge its scope from time to time.

2. Subproject 21 was set up originally for the purpose of providing a drug screening facility at the The total cost of the program amounted to \$5720.00 Unfortunately, internal politios at the, made it inpossible to carry out the program as planned, and so no funds were ever expended in this Subproject. The basis for the\_ change of Subproject 2l from its original goal to the present one is based upon an identical case where Subproject l0 was converted β for use in the project after it became evident that the funds committed under it originally for another purpose could not be used. has since audited Subproject l0 without questioning this type of handling.

3. Accounting for funds-expended by the contractor in this subcroieot will be reflected in the general accounting for Subproject 48.

4. The total charges for this project will not exceed \$5720.00 for a period of one year ending 30 June 1956.

DRAFT/A

23 Jue 1955

[PAGE 4]
5. the prinçipals in this project are TS cleared. Cut-outs and cover arrangements will be used for-dealings with unwitting personnel.

APFROVED FCR OBLIGATION OF FUNDS:

Distribution: Original Cnly

[PAGE 5]
1 January 1955

MEMCRANDUM FCR: THE RECORD

SUBJECT Extension of Time for Project MKULTRA,Subproject 21

Since Subproject 21 has expired and there are still

fumds remaining in the project, Subproject 21 is hereby

extonded for one year from date of expiration.

APPROVED:

Chief.TSS/Chemical"Division

Origiral Only

DRAFT

[PAGE 6]
The principle invosticator, is familiar C with the diphenolic compounds originally synthesized at tho under the dircction of- and is fuily equipped to procecd further the pharmacological testing and bio-assay of such compounds.

It is purposed to test the LD/50 and tho pharmacological action of such compounds and related chenotherapeutic agonts as my be submitted from tiae to tine through the Pathology Departient at wor as modified by the principle investigator. Detailed reports and records will be kept on the bio-ssays and pharmacological tests and submitted as they. become available.

The budget desired for-&his research proposal ist Pergonnel--Laboratory assiatant \$3,000.00 pr annum Animals and animal maintenance 1,000.00 Miscellaneoug laboratory supplies 500.00 Travel 500.00 Total 5,000.00 Institutional overhead 10% 500.00

C is an associate of the and will conduct the work in the facilities of that organization.

PHARMACOLOGICAL TESTING OF CHFEIOTHERAPEUTIC AGENTS FOR CANCSR

[PAGE 7]
SUBJECT:

Project MKULTRA, Subproject 21

1. The scope of subproject 21, Project MKULTRA, is to provide CD/TSS with a-facility where the pharmacolcgical activity of various materials of-interest to the division can be determined in a secure and complete-fashion.

2. The chief investigator, routinely conducts such,tests on large nunbers of materials in the laboratories of the before the materials are screened for anti-cancer-activity.Thus, any materials from CD/ TSS can be included in this\_larger-group withouttheir true identity being known to anyone-outside-the-Agency.

3.All business-with band will be conducted through acting as cut-out.\_\_The attached proposal-indicates-Che-distribution of funds. In addition to the \$5,500.00, a 4% service-charge, or \$220.C0, for the B is required.

4. The total cost of this project for one year ending l-January 1955wi11 not exceed5,720.00

PROGRAM APPFOVED AND RECOMENDED:

SIDNEY GOTTLIEB Chief Chemical Division, TSS

AFPROVED FOR OBLIGATION OF:FUNDS:

Attachment: Froposal

DRAFT/M 10 December 1953

MENORANDUM FOR THE RECORD

[PAGE 8]
ATTEXTION:

Pinance Division

Project NZULTRA, Subproject 21

Vnder the authority granted in the zemorandum dated 13 April 1953 from tho DCI to the DD/A, and the further authority granted in the semorandna dated 17 April 1953 fros the DD/a to the Comptroller on the subjeet, "DD/P-TSS Froject MKULTA," and the memorandum dated 19 June 1953, from the CCI to the DU/A extending the anthority to cover Fiscal Year 195h, Subproject 21, has been approved, and \$5,720.00. of the over-all Project KULTRA fands have been obligated to cover tho subproject's expenses.

SIDNEY GOTTLIEA Chief Cheaical-Division, TSS

FROGRAL APEROVED AND PECOMEHDEDI -APPROVED FOR CBIIGATION 07 FUNDS:

Fesearch Mirector Date:

11 December 1953

NENCRARLUN FORI COMPTROLLER

DEC 21 ENTD