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GHEMICAL VARPARS - UNIIED STATEI

POROCIRIICAL AHET

Derivativea of srgot such as lysergic nold amide, derivativea of marijoana (oamahinn), mesoaline end its derivatives, are being studiei as a basio for the synthesis of Eandidate pojchochericnl
#gonto. Thnge mubstances hase in cormon the ability to produce hellucinations
ted montal eberrations. The greatest difficulty in this group of agents
has ben the establishont of suitable screcning techniquesbn egtive
contrpct rrogran to this ond ia baing rroeacuted with tho. and with the

MLTURALLY OCCURINO TOXING

This croup includes shell fish poison, puffer fisb roioon and the mushroon poiaons from Amenite mscerin. Material is collected fron the natural sources, concentrated and purlfied, Attozpts are then rnde to detorine otructure. Ir those compounds turn out to be mufliciently siaple aynthosis will be attempted. Work on thie groun of torns is baing done uner contract vith the WHor ahell fish roison, and vith Tor the mshroom poiaone. Seerch for tozic cocroundo in thia as vall en other fialds is being aaplified under controct vith subcontrncta include studies of puffer fiah toxin at the and et

(FrO UEITRCHOCAL ETIVATIS of the 8hpr11 1953,

A/B, 1, 26/1