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DATe: 3 February 1953

l. Lysercic Acid is a symthe'ic chenical having cinilar rolccular structures of various ergot derivatives. As is woil-irown, ergot is a rust uhich affects rye during ips growth. Also well-knoun is the fact that ergot has certain properties vhich produco riental derangement, mental and physical disorders, and in certain forms can produce death. Hrgot, hovever, has very valuablc medicinal valuc, particularly in connection with treatment of women befere and after childbirth and in curing certain types of migraine headaches.

2. Iysergic Acid (LSD) has, up until recently, been producsd by the SAlDOz Chenieal organization whose main ttoadçuarters are at Tasel, Switserland. The synthotic crgot (LSD) was doveloped by a Dr. Hoffman, whe is the chief researcher for Sandoz. Cne of Dr. lícffnan's many cutstandin assistants, and apparontly a protoge of Dr. Hoffman's, is. Dr. Rudolph Bircher also a Swiss Hational.

3. Fer many years, it hes tcen well-known that various doctors, nschiatrists, scientists in various countries in Lurope have been cxnerimentin, :ith ergot or Lysergic Acid. This has teen, as far as is knoun, alncst always purchased from the Sendoz organization which sells chemicals to the vorld. This exnerimentation gouerally is of a psychiatric nature tut there have hoen.certain indications that some countries, and possibly the Seviet lnion, ,have considored the use of lysergic Acid fer either cherical uarfare, psychological warfare, or military purposcs.

h. Sinco the unusual proporties of ergot and tore importartly Lysergic Acid havo teen knon to APTICOKE fer somo timc, the development of this chemical has been of intense intercst.

5. In connection with this, the vriter learned long ago that CB of (one of the cutstadine rcscarchers in the Tield of nercotic, hypnotic andt soporific chenicals and drucs) vas doinc researeh vork in Lyser:ié Aeid and uas reportolly advocating U its stady and cce. Subsequenbiy, mode sevemral trips to Eurone anl durin these trips to !rope he visited mnerons indi viduaìs af discusah fricinie Acidviti tha and apet a congidarablo anount , and othors. a Chunen his relarn fror Farope in 1952, made a report in conncction with"this and again strossed the interest in and irportance of Lysergic Acid.

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6. Over a nonth ago, dhis of fice received a dispalea Uuronch the C Contect Division taich indicatod that im (rentioned above) was then visiting the United States, apparentiy fer tho purpose of visiting Sandoz's lleu Tork representatives and having general discussions concernin? Sandez's productions (particularly Igsergic Acid). The infornatien forsarded to this office indicated in a uot too spesific manner that s trip had scre military sirnificanes but this has novor been checked out. This dispateh indicated and that vonla apparentiy spend sone bine citlier at the hone of in company and Hosired cone aithorisablion to proceed in an attent to "puri for informabion concerning Lysergic Acid and other portinent related infomation. Sinco it was
A indicated afler consultation betieen kesef ms.
A  of Secirity, and the writer thel  coula possibly C secure more informnaLion frory Y than ?nyone else, a very general authorization uas given to hin to abtonpt to obtain frone such infornation tha! ho thought portinert. The recults of this have not yet boen made available to Lhis offiee. li, shoild be noted for the record that metous nob in as far as is kom e consultimnt to this Agoney but is a Consultant to the of the and holds ane contract for nary thensands ef dellars fer research puposes. The uriter is net certain inether or. e not, this Aceney in any vay is indiroctly finaneing  shat it has
A been nstablished that  of Ors is ell auare of gska work and apparently through e channels is noro or less able to control thc activity of . C

7. 0n 29 Jamuary 1953,. tand the uriter had a A long discussion vith .rset-sof OiS and ruch ef tiis natorial uas covered in this conferencd. hat nsefulress to this Aoney C will. be has. nol yet bcen asceriaired, hut anparentlyert fecls that . in some ways a problen.

β. For matter of record, apparently chsnists of Uhe B horking for CTS have in the past fou vecks sueecoded in broalting the secrot forpila held hy Sandoz for the nunufnetnre of Lysorgic Acid and have mamufactured for this Agercy a largo quartily of lgsergic Acid uhich is available Cor oar oxperimentation. This cerk is a closoly ruarded ors secret and should not be menbioned generaily.

A