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TO: Chief, Security Research Staff

FROM : Chief, Technical Branch

sUBJECT: ARTICHOKE Interviews with Contacts.

1. On Tuesday, 26 January 195/ between 9:30 and 11:30 All, and the writer talked with two contacts wio have veen cicared to the Secret lcvel in connection with the ARIICHOkE vork. Set out below is a very brief discussion and the results thereof.

1) and is a specialist on the effects of drugs and chemicals on the Central. Nervous Systcn. lie is also a specialist on animal experimentationr thad previously
A been contacted by "andthe writer and had offered encourafement and assistance along ARTICliOKE lines. texplained at this contact that ho had been endeavoring to vork out some tipe of mcasurin device which could be used in accurately measuring the sedative and hypnotic effect of certain drugs and chemicals on small animals vhich would be along lines of interest to ATICHOE experimentation. stated that so far he had not been able to evelop what he rerarded as a sensitive enough arparatus but would continue this work as new idcas came to hin. lle stated that certain use could bo made of the electroencephalograph in animals dowm to the dog level, and that this device could be used in connection with certain types of monkeys but this yould, of course, entail heavy expenses and a considerable amount of time. again offered to test any "new" chemicals that would be developed and stated he would consider further types of arimal experimentation as he Iound time to handle this. requested that ue furnish him with new matcrials and he would watch the various reports that moved across his desk in connection with new and modified chenicals and drurs which he was studying for the

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co-operative prcviously, acain volunteered his sorvices in searchcs for new and prontising materials and stated he personally would attorpt to locate new
chemicals and drugs or set in motion methods that
would turn up new chemicals and drugs of'interest to AllJCHOiE.Hle stated that since the first meeting with
and the writer he had given the matter considerable thought and hc definitely was
intereeted in the possibilitics of lysergic acid.
hd the writer aclmnowledged that lysergic acid and derivatives therefrom were of considerable interest to us but informed
we had little if any access to the material and little technical kowledge of testing, ete. being carried on by or any other organizations using the substance in the U.S.d
stated, throurh the ranifications of the
he could make legitimate,extensive inquiries regarding lysergic acid to the people or any other organization handling it, including hospitals, clinics, etc. where it miht be used in the United States and he would immediately start doing this without disclosing any Afency interest.

sgrin referred to of his Staii and suggested that whenever possible. ne used stated that hc personally would insure the co-operation of his stafr in this work but that the secret nature of the worl: vould not be disclosed.

C3)
A Accorging to time, it the present undergoing a special type of investi-A were not discussed with him. liowever, Cation for tlis Agency and, hencc, AnfICHOiE matters a yoneral pretoxt was able to talk t on long special matters of interest to OSI. Ii was ascertained in this interview that as actively emploved by
G this Arency doing chemical analyses for This work is apparently being handled throuch Eo The conversation discloced that Stafl made analyses of chcmicals'and studics of certain things obtained by this Agency from behind the Iron Curtain-anomade reports in this conncction to this Arency stated that lhe services of his chemists were paiu for at a rate of 5.00 per hour per individual which included all the necessary laboratory

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facilities and matcrials for testing.
stated that although his work was heavy, le wourd be
glad to do analytical work for but that
should be laid on through the sane chawels he has
been- using previously. The-bulkof the conversation
between nd as of ceneral in
terest to AlTiCliOkE but of primary interest to OSI and ras not briefed on AlTICHlOlE or cut into the
AuilChonE program in any vay uhatsoever.