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MMORANDUM FOR TIE RECORD

SUBJECT: .. Trip to Lexingtcn, Kentucky on 15 July 1954

1. Writer met with Dr. Earris Isbell and Dr. E. W. Pelikan at Lexington, Kentucky to discuss CA l0l problems at the xcquest of Dr. Isbell. The attached rapers cover most of ths topics discussed. The coaclusions w reached ani the plsns rmade will be reported hert.

2. On the basis of the vork that has been completed on the -.CA l0l, it vas decided that only s fev more experirents vould be done. These would consist of one in which the blcod pressure erfects would be neasured during the course of the iatoxicstion end their rovereal vould be atterpted with varicus orally active sympathoniretic aaines. In eddition, the drug vill be smoked to see if it is effective by this route ara to dstérss the dose.

3. I dolivéred l00 ng ISD, 1 Sa. Cocaine, anã 1 os of Potassiua tellurite to Ed for his work. Ei will get busy with i.v. aninal tests on the tellurite end vill,vse the other material in the Areour projecs. Ir. Isbell cclldn't undertake any studies with the tellurite becsuse of the neture of his situtica. He save me 6-50 mg vials of LSD for stock and caid that.le woulá order 2 gms more frca Sandoz in oréer to have plenty on hand.

4. Cn-the colloidal suifur ousiness, Ea said that the dose wes 5-l0 ul i.m. snd thst it vould proluce exerucieting pain for 8 to l0 hours. It is not detectable vith X-ray and is available corercially. No toxicity probles exists end no after-effects eppeer.

Declaesified by187475
date -—4 FEE 1977

A13

DRAFT/IWD/EK 16 Jy1954

Original Caly