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HHKH m

(b3)

Thank you very much forthe sample of the barbiturate antagonist. I will look forward with great interest to learning its'.chemical compositicn and more about its pharmacological actions. Meanwhile, perhaps we can attempt some pilot work with animals. It would be of interest to see whether it would precipitate abstinence from barbiturates in addicted dogs.

All best wishes for a happy and successful New Year.

Yours very sincerely,

Narris Dbel

Harris Isbell, M. D. Director

HI:1w

A-251

Jepartm of HEALTH, EDUCATION, AND ¿LFAre• Public Health Service NATIONAL INSTITUTES OF HEALTH

IM REFLYING ADORESS THE NATIONAL INSTTTOTE OF MENTAL HTALTK ADOICTIOM RESEARCH CENTER U.S. PUOLIC HEALTH SRvICz.HOSTAL P. O, Bo z00σ LEEIMGTON, KENTUCKY

27 December 1956

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