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In 0ctober 1952 and the writer attended a conference at Wfor the purpose of a general diacussion concerning yarious drugs and to meet a oscientiat by the name of who' was at that time and reentering private practice as a chemist and, research pecialist raccording toi had done basio re search in the extraction of very:active elements from Cannabis and was regarded by Sopla, and as an outstanding young acientist. s In a general discussion concarning possibledrugsof interest tothe and Artichoke work stated that hejfalt that the Mexican plant known as Piule.(not.Peyots was wellworth'exploring for its alleged narcotic effeots. stated that there was very'little known about'this'plant and that it apparently was ueed by the Mexican Indians in early tines as asort of truth serun and also usad foritsintoxicating effect in their religious ceremonies. statedthat if the aeeds or drug-producing parts. of the plantioould be obtained, he would gladly volunteer toaxtraot the narcotic alements fromthe plantand'determine whether or, not these alementa would be, of valuetowardour,work.
3.Consequently,jafter adiscusasion, Tand the writer feltthat since Schad expressed interest (and by reputation Wasan exceptionally competent sciantist)that anleffort should be made to traok down the plant Piuleand have it analyzed by and by other competent bio-chemists. Aocordingly, the writer laid the a problembefore fof OSI:and'requestedtha begin,preliminary ressarch on:thie, planti
4.TThe writer:told toaxamine andtrate down"all'pos sibleinformation, onPiule and f this preliminary report indicated "that theiplant had,finfaot, 'properties of value toour work. We would begin full-aoale research on:the, plant including, the obtaining of the'plant tselfise Thereafter, began a systematic. reseerch and turned up considerableinformation whichin sopinion and the opinion orthe writer clearly,warranted extensive, research,and obtaining