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MEMORANDUM FORI Chief,

SUBJECT

: Review of Proposal on Screening of Compounds Effecting Behavior

REFERENCE Memorandum for Director, Subject, Research and Development Requirements of the Clandestine Services

1. Attached ia the Proposal upon which you solicited \comments. I have discussed the paper at sorme length with appropriate individuals in this Division and find thaê we are in'general agreement on seversl points. First, the brevity of description of experimental work to be performed is such that a assessment of the "quality of content" of the proposal doee'not appezs to be possible particularly in view of the very epecialized interests ef lin these matters. Far from being negative in this respecti this conceneun appears to involve the thought that the prcposed work covers such a broad area and involves so many poesible test substances that some materials of iuterest must almost certainly be discovered,

2. Untll some point is reached in the work where possible enditems can be identifled, it is difficuit to predict the ultimate uaefulness of this research approach to  In this connection I can only indicate the referenced memorandum which discusses the\requirements for chemical and biological agents effecting behavior and point out that this approach is certainly a plausible one.

3. In the recent past and at present jhas no work in progrese nor does It contcmplate apy which is designed to identiiy new chemical or biological sgents effecting behavior. There is therefore no questien of any duplication of effort or overlap in the case of this proposed work.

Attachment:

Copy C of Proposal 120765-1

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