C00021937

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REGISTERED

Attention: Mr.

Subject : Contract No. Task Order No. 0 Amendment No. 02

Gentlemen:

Reference is made to the subject Task Order entered into with your Corporation as of 1 April 1969, as amended, for the pharmacological screening of potentially useful new agents.

\- By this Amendment it is mutually agreed that the original scope of work is expanded to include a sub-contract with tor toxicity studies.

Based on the foregoing, the estimated cost of performance "of the work of the Contract, exclusive of the fixed fee, is increased in the amount of

As a result of the above, the new total estimated cost, exclusive of the fixed fee, shall be

The fixed fee payable to the Contractor shall remain at.

The new total estimated cost plus fixed fee is now

23 December 1970

C000219371

70

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The completion date for performance of work under this Task Order shall be extended to 31 Docember 1971. It is understood that after 1 May l971 the only work chargeable to this Contract shall be that performed by the sub-contractor.

All other terms and conditions shall remain unchanged.

Please indicate your acceptance of the forogoing by signing the original and enclosed two copies, retaining one copy for your files and returning to the undersigned at the sarliest practicable date, the original and remaining copy.

EXECUTED:

Very truly yours,

Contracting Orficer

BY:

TITLE:

C00021937

70

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