C00021940

[PAGE 2]
MEMORANDUM FOR:

SUBJECT:

F:/low.up Transfer of Funds to EARL for Bvatuatto Studiec in Hiuman-Velunteers .Stvdy of Melical Volizpteors

1.This requested transfer of funds is in support of the

and quantify the effects in hunans of the

administration of agents bélonging to the glycolate class. The .

study will be carried out within the Medical Volunteer Program at

EARL under the direction of Dr.

2. Agents of the glycolate class are of interest because of the

serious threat certain examples cases of théSclass present as potential

incapacitants. The Soviets are known to be actively working in the

glycolate area. Our most effective example item is f3167. This

partially investigated item is effective fin animals and

probably also in man, as evidenced by several laboratory accidents.

Because the lof administration are the

routes of truc potential threat to US.VIP's and other key personnel,

it is essential that the present\_existing data on intramuscular injection

inhumans be extended to include the

Simultaneously, information and plans will be developed to implement

C00021940"

26

DRAFT

16 February 1971

[PAGE 3]
Page 21

3. Contingent upon the results obtained and evidence of a

clear potential threat, follow-on work at approximately the same

level of effort can be expected for the development of needed counter-

measures.

.EARL was selected for this work because of their unique

experience with f3167, and because it has volunteer human studies

on-going in a carefully controlled environment. Coordination has

been affected with

Jand with Dr.

Director of Laboratories at Edgewood.

5. Dr.

will be the

project officer with responsibility for monitoring the execution of mSECKET SECKET

the task. The work will be CLASSIFIED and Agency association wte inlersifel
EARL Will be'CONFIDENTLAL.

6. The

recommends

the approval of the transfer of \$37, 000 to Project AD 21 Task 03

(Follow-on Study of Medical Volunteers) at EARL under the direction

f Dr.

C00021940

DRAFT

16 February 1971