MORI 149537

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Ae direoted, at leaat l0 professional contacts xaremade darirg tho tine os
18-29 Cotobarl95h.rery bontact sade, by groat good ftune, through agoncy
preparabion and xhols-bearted cooparation:of all concerned, had rost gratiying
rasulta. Craiof the dagired substenoss colleeted, han, a conzeroial Yalve o ovar
600 dollara,the othar a production ralua o ovar lc0o dollars. Cthers are'rare
tens, ecnrercially not obtainabls,all,sectrad.vithoat expansa.to this agoncy. n additien valuabla data and fileswore collgcted,ss well asspecirans'fro atyand:guidanca: Iheperscnal contact TWher3
cutatarding collooti an seiaotiats,fald rrienis, and tquaintanees dithsield:aganta, aca rasults in over  caaco.
rscurthy proven.tbe yalue or dolitranoy sigins.
Ha gites dalitroua s dofinita plses intba pes ara or anasthealclotys designati
13 as aalgsaia ratar than as an anaathatiss ca a bordar lina agent,aince
kaepa the patient at leasb partiallr sonsoiona  It makes tbe antire oyetaa
Ansenaibile to pain, in contrast to d localianastbetlo leaving the patiant abla
to obey irs traotior f the doetor ard titaiaag tho aility to use the auscles
whiia ie caasss forgetfuloosa tho blood clrotlation rate ia not greatlygloved,
cral swgory is posaible with lesa pleeding and dopreasicn aa weill as doep anes
thasia ara cly cbtaired after verylargo doses.politrone baa boes nsed succesafally alons orincobinstion gith other druga, sach at curare,succinyl
schloride, cccaine, nitrous, axide and sther (sea detallad deta cn, tabla attacbed
in dental, sye, ear, cose andithroab argorya ani in bronchioscopy, causinc in
ccntras te' pantothal no spaana is daaiaivep axtended and prolonged relisl mos pain in adrancad catcer anliia denarrboidrasoval.iIts uss in ohilcoir isla progress.Zor dotailodclinicalreghlty sos Sable I abtached Hathods or Acninistration Cral Uset tended exparixsata ara plamed after coapletion'in ths lebaratorlee of atudies to improva tbaiphyaicalipropertos of dolitrore such de suspension or solution,raneral drodor end adjaataoot to the desirable pd

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2 3atranuacular Injeoticattne scute asinglag paia, lastieg abeut 2 infecoa of s locel admtaa, may bd ovarccns by, the sinaltanacus-or precediag aneathaiio, sich as procaine, mhe raisiog or tha ara above the borisontal leval dn dass injeokons ars zada in the arz, ara alcs recccendel to foreatall pein iIntravenoes Intectiony me tes op tbe Seeatly Asproved Lvephilised dol Joahotrs, at aph.or h.5, given internittensly.by vain, ss ecassary,isrocon and Ar. ataantanned. by the agencr,twoughttha, coopsratlok o 2101

SBening ieath 1 385

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B3 Eaks -he ssotlod chler of solvans preparatiora, tha.
i total synthosis a Is (Lysergio acid) ant f gonovi ia \*pquires rcoedre that kdlo and largar atockplle quantitlss canrot to erpected
suah 3 scaples
of ar2o0a715a varaiou to srzonevino, mishlss atap aaldiardrazida paredin the hiocrani ad. are avallaklato us benalenend.taar-in paratrooper the iron cu its ahonley ght he made aveilable to thia ageny T9 iu tiis fleld sra carlad on is the ss cireetica a Ciboaye illadenat The pzeasue argotaliys alkaloics in'thls Floridan and ko pat basn 29 cinna lor a rther study and ran aastnu ctr lalpla this cooperativs Passars Sss Past sotitg ssdatite wizh aDesthatig propartiag. clo such subasnce, shan ecoenal ih ansathetlo srd fypnote proparties, was suggested Zozevar athe duvalopens of, sslaotion of such apocial'substarcds was cisucansl Anelsuing posatblybarbituretes whicd mighs Sa zolakls andreadilyvolatilised oigarettesytanggasted.bo and adopted in the rse of aslaa Thia lattor use bad boen repertod by 83

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Nald s2 3

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a 2

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A

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