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Transfer of Funds to EARL for Follow-up Study of Medical Volunteers .

1. This requested transfer of funds is in support of the "Project. The goal of this study is to define and quantify the effects in humans of the administration of agentș belonging to the glycolate class. The study will be carried out within the Medical Volunteer Program at EARL7 under the direction of Dr.

2. Agents of the glycolate class are of interest because of the serious threat certain examples of this class present as potential incapacitants. The Soviets are known to be actively working in the glycolate area. Our most effective example item is.f3167 This partially investigated item is effective in animals and probably also in man, as evidenced by several laboratcry zccidents. Because the" routes of administration are the routes of true potential threat to U.S. VIP's and other key personnel, it is essential that the present, existing data on 1

in humans be extended to include the 1 Simultaneously, information and plans will be developed to implement countermeasures as required.

3. Contingent upon the results obtained and evidence of a clear potential threat, follow-on work at approximately the same level of effort can be expected for the development of needed countermeasures.

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MEMORANDUM FOR:

SUBJECT:

y

17 February 1971

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4. EARL was selected for this work because of their unique experience with f3167, and because it has volunteer human studies on-going in a carefully controlled environment. Coordination has been affected with Dr. and with Dr. Director of Laboratories at Edgewood

5. Dr. extension.will be the project officer with responsibility for monitoring the execution of the task. The work will be classified SECRET and Agency association will be classified CONFIDENTIAL.

6. The recommends the approval of the transfer of S37, 000ho Project AD 21 Task 03 (Follow-on Study of Medical Volunteers) at EARL under the direction of Dr.

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