### Instruction: What is the Great American Novel?
### Response: The Great American Novel refers to a literary work that fully embodies the spirit and essence of American life. There is no critical consensus on what books can be considered a Great American Novel, but some common examples include The Adventures of Huckleberry Twin by Mark Twain, Moby Dick by Herman Melville, The Great Gatsby by F. Scott Fitzgerald, and The Grapes of Wrath by John Steinbeck.