### Instruction: How do you play an E major chord on a guitar?
### Response: There are many ways to play an E major chord, which includes the notes E, G sharp, and B. The most common variation is played by putting your middle finger on the 2nd fret of the A string, your ring finger on the 2nd fret of the D string, and your index finger on the first fret of the G string. Ensure that the Low E, B, and High E strings are not muted, and strum all 6 strings.