Disease (ORPHA:963):
Acromegaly

Associated phenotypes (HPO):
id: HP:0001869
hpo_term: Deep plantar creases
chpo_term: 跖部深褶
id: HP:0002758
hpo_term: Osteoarthritis
chpo_term: 骨关节炎
id: HP:0002829
hpo_term: Arthralgia
chpo_term: 关节疼痛
id: HP:0003859
hpo_term: Cortical diaphyseal thickening of the upper limbs
chpo_term: 上肢骨干皮质增厚
id: HP:0004099
hpo_term: Macrodactyly
chpo_term: 巨指
id: HP:0006191
hpo_term: Deep palmar crease
chpo_term: 掌褶纹深
id: HP:0000158
hpo_term: Macroglossia
chpo_term: 巨舌症
id: HP:0000276
hpo_term: Long face
chpo_term: 长脸
id: HP:0000280
hpo_term: Coarse facial features
chpo_term: 面容粗糙
id: HP:0000293
hpo_term: Full cheeks
chpo_term: 脸颊丰满
id: HP:0000303
hpo_term: Mandibular prognathia
chpo_term: 下颌前突
id: HP:0000337
hpo_term: Broad forehead
chpo_term: 宽前额
id: HP:0000400
hpo_term: Macrotia
chpo_term: 巨耳畸形
id: HP:0000445
hpo_term: Wide nose
chpo_term: 宽鼻
id: HP:0000818
hpo_term: Abnormality of the endocrine system
chpo_term: 内分泌系统异常
id: HP:0000830
hpo_term: Anterior hypopituitarism
chpo_term: 垂体前叶功能减退症
id: HP:0000845
hpo_term: Elevated circulating growth hormone concentration
chpo_term: 生长激素水平升高
id: HP:0000975
hpo_term: Hyperhidrosis
chpo_term: 多汗症
id: HP:0001051
hpo_term: Seborrheic dermatitis
chpo_term: 脂溢性皮炎
id: HP:0001072
hpo_term: Thickened skin
chpo_term: 皮肤增厚
id: HP:0001176
hpo_term: Large hands
chpo_term: 巨手
id: HP:0001182
hpo_term: Tapered finger
chpo_term: 锥形指
id: HP:0001386
hpo_term: Joint swelling
chpo_term: 关节肿胀
id: HP:0001769
hpo_term: Broad foot
chpo_term: 宽足
id: HP:0011760
hpo_term: Pituitary growth hormone cell adenoma
chpo_term: 垂体生长激素腺瘤
id: HP:0011334
hpo_term: Facial shape deformation
chpo_term: 脸型异常
id: HP:0012185
hpo_term: Constrictive median neuropathy
chpo_term: 压迫性正中神经病变
id: HP:0012471
hpo_term: Thick vermilion border
chpo_term: 厚红唇缘
id: HP:0012802
hpo_term: Broad jaw
chpo_term: 宽下颌
id: HP:0025406
hpo_term: Asthenia
chpo_term: 虚弱
id: HP:0025693
hpo_term: Pituitary macroadenoma
chpo_term: 垂体大腺瘤
id: HP:0030269
hpo_term: Increased circulating insulin-like growth factor 1 concentration
chpo_term: 循环胰岛素样因子1水平升高
id: HP:0100540
hpo_term: Palpebral edema
chpo_term: 眼睑水肿
id: HP:0100607
hpo_term: Dysmenorrhea
chpo_term: 痛经
id: HP:0000238
hpo_term: Hydrocephalus
chpo_term: 脑积水
id: HP:0000602
hpo_term: Ophthalmoplegia
chpo_term: 眼肌麻痹
id: HP:0000689
hpo_term: Dental malocclusion
chpo_term: 牙齿错位咬合
id: HP:0000789
hpo_term: Infertility
chpo_term: 不孕症/不育症
id: HP:0000802
hpo_term: Impotence
chpo_term: 阳痿
id: HP:0000846
hpo_term: Adrenal insufficiency
chpo_term: 肾上腺功能不全
id: HP:0000869
hpo_term: Secondary amenorrhea
chpo_term: 继发性闭经
id: HP:0000876
hpo_term: Oligomenorrhea
chpo_term: 月经稀发
id: HP:0000956
hpo_term: Acanthosis nigricans
chpo_term: 黑棘皮病
id: HP:0000998
hpo_term: Hypertrichosis
chpo_term: 多毛症
id: HP:0001061
hpo_term: Acne
chpo_term: 痤疮
id: HP:0001081
hpo_term: Cholelithiasis
chpo_term: 胆石症
id: HP:0001123
hpo_term: Visual field defect
chpo_term: 视野缺损
id: HP:0001639
hpo_term: Hypertrophic cardiomyopathy
chpo_term: 肥厚型心肌病
id: HP:0001653
hpo_term: Mitral regurgitation
chpo_term: 二尖瓣反流
id: HP:0002155
hpo_term: Hypertriglyceridemia
chpo_term: 高甘油三酯血症
id: HP:0002315
hpo_term: Headache
chpo_term: 头痛
id: HP:0002953
hpo_term: Vertebral compression fracture
chpo_term: 椎体压缩性骨折
id: HP:0003233
hpo_term: Decreased HDL cholesterol concentration
chpo_term: 低α-脂蛋白血症
id: HP:0003326
hpo_term: Myalgia
chpo_term: 肌痛
id: HP:0005266
hpo_term: Intestinal polyp
chpo_term: 肠息肉
id: HP:0006767
hpo_term: Pituitary prolactin cell adenoma
chpo_term: 垂体泌乳素腺瘤
id: HP:0006824
hpo_term: Cranial nerve paralysis
chpo_term: 颅神经麻痹
id: HP:0007440
hpo_term: Generalized hyperpigmentation
chpo_term: 泛发性色素沉着
id: HP:0008245
hpo_term: Pituitary hypothyroidism
chpo_term: 垂体性甲状腺功能减退症
id: HP:0010541
hpo_term: Cutis gyrata of scalp
chpo_term: 头皮回状纹
id: HP:0011675
hpo_term: Arrhythmia
chpo_term: 心律失常
id: HP:0012452
hpo_term: Restless legs
chpo_term: 不宁腿
id: HP:0030166
hpo_term: Night sweats
chpo_term: 盗汗
id: HP:0012378
hpo_term: Fatigue
chpo_term: 疲乏
id: HP:0033794
hpo_term: Acral overgrowth
chpo_term: 肢端过度生长
id: HP:0000044
hpo_term: Hypogonadotropic hypogonadism
chpo_term: 低促性腺激素性性腺功能减退症
id: HP:0000164
hpo_term: Abnormality of the dentition
chpo_term: 牙列异常
id: HP:0000336
hpo_term: Prominent supraorbital ridges
chpo_term: 眶上嵴突出
id: HP:0000664
hpo_term: Synophrys
chpo_term: 连眉
id: HP:0000687
hpo_term: Widely spaced teeth
chpo_term: 牙间隙增宽
id: HP:0000716
hpo_term: Depression
chpo_term: 抑郁
id: HP:0000739
hpo_term: Anxiety
chpo_term: 焦虑
id: HP:0000819
hpo_term: Diabetes mellitus
chpo_term: 糖尿病
id: HP:0000822
hpo_term: Hypertension
chpo_term: 高血压
id: HP:0000855
hpo_term: Insulin resistance
chpo_term: 胰岛素抵抗
id: HP:0000870
hpo_term: Increased circulating prolactin concentration
chpo_term: 泌乳素水平升高
id: HP:0001609
hpo_term: Hoarse voice
chpo_term: 声音嘶哑
id: HP:0002007
hpo_term: Frontal bossing
chpo_term: 前额突出
id: HP:0002076
hpo_term: Migraine
chpo_term: 偏头痛
id: HP:0002230
hpo_term: Generalized hirsutism
chpo_term: 全身性多毛症
id: HP:0002808
hpo_term: Kyphosis
chpo_term: 脊柱后凸畸形（驼背）
id: HP:0003401
hpo_term: Paresthesia
chpo_term: 感觉异常
id: HP:0003416
hpo_term: Spinal canal stenosis
chpo_term: 椎管狭窄
id: HP:0005978
hpo_term: Type II diabetes mellitus
chpo_term: 2型糖尿病
id: HP:0005987
hpo_term: Multinodular goiter
chpo_term: 多结节性甲状腺肿
id: HP:0010535
hpo_term: Sleep apnea
chpo_term: 睡眠呼吸暂停
id: HP:0010609
hpo_term: Skin tags
chpo_term: 皮赘
id: HP:0031653
hpo_term: Abnormal heart valve physiology
chpo_term: 心脏瓣膜生理异常
id: HP:0046504
hpo_term: Decreased libido
chpo_term: 性欲减退
id: HP:0100518
hpo_term: Dysuria
chpo_term: 排尿困难
id: HP:0100786
hpo_term: Hypersomnia
chpo_term: 过度睡眠
id: HP:0100829
hpo_term: Galactorrhea
chpo_term: 溢乳