Disease (ORPHA:652):
MEN1
Multiple endocrine neoplasia type 1
Wermer syndrome

Associated phenotypes (HPO):
id: HP:0003072
hpo_term: Hypercalcemia
chpo_term: 高钙血症
id: HP:0008200
hpo_term: Primary hyperparathyroidism
chpo_term: 原发性甲状旁腺功能亢进症
id: HP:0008208
hpo_term: Parathyroid hyperplasia
chpo_term: 甲状旁腺增生
id: HP:0010615
hpo_term: Angiofibromas
chpo_term: 血管纤维瘤
id: HP:0031058
hpo_term: Impairment of activities of daily living
chpo_term: 日常生活活动障碍
id: HP:0000802
hpo_term: Impotence
chpo_term: 阳痿
id: HP:0000849
hpo_term: Adrenocortical abnormality
chpo_term: 肾上腺皮质异常
id: HP:0001012
hpo_term: Multiple lipomas
chpo_term: 多发性脂肪瘤
id: HP:0001824
hpo_term: Weight loss
chpo_term: 体重减轻
id: HP:0002014
hpo_term: Diarrhea
chpo_term: 腹泻
id: HP:0002020
hpo_term: Gastroesophageal reflux
chpo_term: 胃食管反流
id: HP:0002027
hpo_term: Abdominal pain
chpo_term: 腹痛
id: HP:0002044
hpo_term: Zollinger-Ellison syndrome
chpo_term: Zollinger-Ellison 综合征
id: HP:0002150
hpo_term: Hypercalciuria
chpo_term: 高钙尿症
id: HP:0002893
hpo_term: Pituitary adenoma
chpo_term: 垂体腺瘤
id: HP:0002894
hpo_term: Neoplasm of the pancreas
chpo_term: 胰腺肿瘤
id: HP:0004349
hpo_term: Reduced bone mineral density
chpo_term: 骨密度降低
id: HP:0004398
hpo_term: Peptic ulcer
chpo_term: 消化性溃疡
id: HP:0005605
hpo_term: Large cafe-au-lait macules with irregular margins
chpo_term: 边缘不规则的较大咖啡牛奶斑
id: HP:0006767
hpo_term: Pituitary prolactin cell adenoma
chpo_term: 垂体泌乳素腺瘤
id: HP:0040306
hpo_term: Decreased male libido
chpo_term: 男性性欲低下
id: HP:0100829
hpo_term: Galactorrhea
chpo_term: 溢乳
id: HP:0500167
hpo_term: Hypergastrinemia
chpo_term: 高胃泌素血症
id: HP:0000141
hpo_term: Amenorrhea
chpo_term: 闭经
id: HP:0000169
hpo_term: Gingival fibromatosis
chpo_term: 牙龈纤维瘤病
id: HP:0000716
hpo_term: Depression
chpo_term: 抑郁
id: HP:0000736
hpo_term: Short attention span
chpo_term: 注意力短暂
id: HP:0000787
hpo_term: Nephrolithiasis
chpo_term: 肾结石
id: HP:0000822
hpo_term: Hypertension
chpo_term: 高血压
id: HP:0000845
hpo_term: Elevated circulating growth hormone concentration
chpo_term: 生长激素水平升高
id: HP:0000853
hpo_term: Goiter
chpo_term: 甲状腺肿
id: HP:0001254
hpo_term: Lethargy
chpo_term: 昏睡
id: HP:0001289
hpo_term: Confusion
chpo_term: 意识模糊
id: HP:0001293
hpo_term: Cranial nerve compression
chpo_term: 颅神经受压
id: HP:0001579
hpo_term: Primary hypercortisolism
chpo_term: 原发性皮质醇增多症
id: HP:0001944
hpo_term: Dehydration
chpo_term: 脱水
id: HP:0002013
hpo_term: Vomiting
chpo_term: 呕吐
id: HP:0002018
hpo_term: Nausea
chpo_term: 恶心
id: HP:0002019
hpo_term: Constipation
chpo_term: 便秘
id: HP:0002039
hpo_term: Anorexia
chpo_term: 厌食症
id: HP:0002248
hpo_term: Hematemesis
chpo_term: 呕血
id: HP:0002249
hpo_term: Melena
chpo_term: 黑便
id: HP:0002315
hpo_term: Headache
chpo_term: 头痛
id: HP:0002588
hpo_term: Duodenal ulcer
chpo_term: 十二指肠溃疡
id: HP:0002659
hpo_term: Increased susceptibility to fractures
chpo_term: 骨折易感性增加
id: HP:0002797
hpo_term: Osteolysis
chpo_term: 骨质溶解
id: HP:0002858
hpo_term: Meningioma
chpo_term: 脑膜瘤
id: HP:0002890
hpo_term: Thyroid carcinoma
chpo_term: 甲状腺癌
id: HP:0003118
hpo_term: Increased circulating cortisol level
chpo_term: 血皮质醇水平增加
id: HP:0006723
hpo_term: Intestinal carcinoid
chpo_term: 肠道类癌
id: HP:0006744
hpo_term: Adrenocortical carcinoma
chpo_term: 肾上腺皮质癌
id: HP:0007449
hpo_term: Confetti-like hypopigmented macules
chpo_term: 斑驳样色素减退斑
id: HP:0011407
hpo_term: Proportionate tall stature
chpo_term: 成比例高身材
id: HP:0011760
hpo_term: Pituitary growth hormone cell adenoma
chpo_term: 垂体生长激素腺瘤
id: HP:0012197
hpo_term: Insulinoma
chpo_term: 胰岛素瘤
id: HP:0012232
hpo_term: Shortened QT interval
chpo_term: QT间期缩短
id: HP:0030405
hpo_term: Pancreatic endocrine tumor
chpo_term: 胰腺内分泌肿瘤
id: HP:0032044
hpo_term: Decreased vigilance
chpo_term: 警觉性降低
id: HP:0040085
hpo_term: Abnormal circulating aldosterone
chpo_term: 循环醛固酮水平异常
id: HP:0100570
hpo_term: Carcinoid tumor
chpo_term: 类癌
id: HP:0001259
hpo_term: Coma
chpo_term: 昏迷
id: HP:0002666
hpo_term: Pheochromocytoma
chpo_term: 嗜铬细胞瘤
id: HP:0002888
hpo_term: Ependymoma
chpo_term: 室管膜瘤
id: HP:0003144
hpo_term: Increased serum serotonin
chpo_term: 血清5-羟色胺（血清素）水平升高
id: HP:0003528
hpo_term: Elevated calcitonin
chpo_term: 降钙素升高
id: HP:0006780
hpo_term: Parathyroid carcinoma
chpo_term: 甲状旁腺癌
id: HP:0008291
hpo_term: Pituitary corticotropic cell adenoma
chpo_term: 垂体促肾上腺皮质激素腺瘤
id: HP:0011151
hpo_term: Atypical absence status epilepticus
chpo_term: 非典型失神癫痫持续状态
id: HP:0011759
hpo_term: Pituitary gonadotropic cell adenoma
chpo_term: 垂体促性腺激素腺瘤
id: HP:0011761
hpo_term: Pituitary null cell adenoma
chpo_term: 垂体裸细胞腺瘤
id: HP:0011762
hpo_term: Pituitary thyrotropic cell adenoma
chpo_term: 垂体促甲状腺素腺瘤
id: HP:0030404
hpo_term: Glucagonoma
chpo_term: 胰高血糖素瘤
id: HP:0030445
hpo_term: Pulmonary carcinoid tumor
chpo_term: 肺类癌
id: HP:0100522
hpo_term: Thymoma
chpo_term: 胸腺瘤