Disease (ORPHA:331235):
Selective immunoglobulin M deficiency
Selective IgM deficiency

Associated phenotypes (HPO):
id: HP:0002719
hpo_term: Recurrent infections
chpo_term: 反复感染
id: HP:0032169
hpo_term: Severe infection
chpo_term: 重度感染
id: HP:0001047
hpo_term: Atopic dermatitis
chpo_term: 特应性皮炎
id: HP:0001510
hpo_term: Growth delay
chpo_term: 生长延迟
id: HP:0200043
hpo_term: Verrucae
chpo_term: 疣
id: HP:0030880
hpo_term: Raynaud phenomenon
chpo_term: 雷诺现象
id: HP:0002850
hpo_term: Decreased circulating total IgM
chpo_term: 循环总IgM下降
id: HP:0002205
hpo_term: Recurrent respiratory infections
chpo_term: 反复呼吸道感染
id: HP:0012432
hpo_term: Chronic fatigue
chpo_term: 慢性疲劳
id: HP:0000491
hpo_term: Keratitis
chpo_term: 角膜炎
id: HP:0002720
hpo_term: Decreased circulating IgA level
chpo_term: 循环IgA下降
id: HP:0004315
hpo_term: Decreased circulating IgG level
chpo_term: 循环IgG水平降低
id: HP:0011109
hpo_term: Chronic sinusitis
chpo_term: 慢性鼻窦炎
id: HP:0000010
hpo_term: Recurrent urinary tract infections
chpo_term: 复发性尿路感染
id: HP:0002110
hpo_term: Bronchiectasis
chpo_term: 支气管扩张
id: HP:0032261
hpo_term: Nontuberculous mycobacterial pulmonary infection
chpo_term: 非结核分枝杆菌肺部感染
id: HP:0032262
hpo_term: Pulmonary tuberculosis
chpo_term: 肺结核
id: HP:0002960
hpo_term: Autoimmunity
chpo_term: 自身免疫
id: HP:0000872
hpo_term: Hashimoto thyroiditis
chpo_term: 桥本甲状腺炎
id: HP:0002725
hpo_term: Systemic lupus erythematosus
chpo_term: 系统性红斑狼疮
id: HP:0001370
hpo_term: Rheumatoid arthritis
chpo_term: 类风湿关节炎
id: HP:0001973
hpo_term: Autoimmune thrombocytopenia
chpo_term: 自身免疫性血小板减少症
id: HP:0001904
hpo_term: Neutropenia in presence of anti-neutropil antibodies
chpo_term: 抗中性粒细胞抗体阳性的中性粒细胞减少症
id: HP:0003493
hpo_term: Antinuclear antibody positivity
chpo_term: 抗核抗体阳性
id: HP:0012204
hpo_term: Recurrent vulvovaginal candidiasis
chpo_term: 复发性外阴阴道念珠菌病
id: HP:0100658
hpo_term: Cellulitis
chpo_term: 蜂窝织炎
id: HP:0002840
hpo_term: Lymphadenitis
chpo_term: 淋巴结炎
id: HP:0005353
hpo_term: Recurrent herpes
chpo_term: 复发性疱疹
id: HP:0000388
hpo_term: Otitis media
chpo_term: 中耳炎
id: HP:0025439
hpo_term: Pharyngitis
chpo_term: 咽炎
id: HP:0031691
hpo_term: Severe viral infection
chpo_term: 重症病毒感染
id: HP:0030757
hpo_term: Tooth abscess
chpo_term: 牙脓肿
id: HP:0033430
hpo_term: Non-infectious meningitis
chpo_term: 非感染性脑膜炎
id: HP:0011370
hpo_term: Recurrent cutaneous fungal infections
chpo_term: 复发性皮肤真菌感染
id: HP:0007499
hpo_term: Recurrent staphylococcal infections
chpo_term: 反复葡萄球菌感染
id: HP:0100537
hpo_term: Fasciitis
chpo_term: 筋膜炎
id: HP:0002837
hpo_term: Recurrent bronchitis
chpo_term: 复发性支气管炎
id: HP:0031292
hpo_term: Cutaneous abscess
chpo_term: 皮肤脓肿
id: HP:0032275
hpo_term: Recurrent shingles
chpo_term: 复发性带状疱疹
id: HP:0012203
hpo_term: Onychomycosis
chpo_term: 甲癣
id: HP:0009098
hpo_term: Chronic oral candidiasis
chpo_term: 慢性口腔念珠菌病
id: HP:0002028
hpo_term: Chronic diarrhea
chpo_term: 慢性腹泻
id: HP:0032170
hpo_term: Severe varicella zoster infection
chpo_term: 重度水痘带状疱疹感染
id: HP:0012393
hpo_term: Allergy
chpo_term: 过敏
id: HP:0003193
hpo_term: Allergic rhinitis
chpo_term: 过敏性鼻炎
id: HP:0002099
hpo_term: Asthma
chpo_term: 哮喘
id: HP:0031047
hpo_term: Paraproteinemia
chpo_term: 副蛋白血症
id: HP:0006775
hpo_term: Multiple myeloma
chpo_term: 多发性骨髓瘤
id: HP:0012539
hpo_term: Non-Hodgkin lymphoma
chpo_term: 非霍奇金淋巴瘤
id: HP:0002890
hpo_term: Thyroid carcinoma
chpo_term: 甲状腺癌
id: HP:0012126
hpo_term: Stomach cancer
chpo_term: 胃癌
id: HP:0045080
hpo_term: Decreased proportion of CD3-positive T cells
chpo_term: CD3+T细胞比例减低
id: HP:0032218
hpo_term: Decreased proportion of CD4-positive T cells
chpo_term: CD4+T细胞比例减低
id: HP:0005415
hpo_term: Decreased proportion of CD8-positive T cells
chpo_term: CD8 + T细胞数目减低
id: HP:0030380
hpo_term: Decreased proportion of transitional B cells
chpo_term: 过渡性 B 细胞比例减低
id: HP:0032140
hpo_term: Decreased specific antibody response to vaccination
chpo_term: 疫苗应答特异性抗体降低
id: HP:0100280
hpo_term: Crohn's disease
chpo_term: 克罗恩氏病
id: HP:0002788
hpo_term: Recurrent upper respiratory tract infections
chpo_term: 复发性上呼吸道感染
id: HP:0006532
hpo_term: Recurrent pneumonia
chpo_term: 反复肺炎
id: HP:0011108
hpo_term: Recurrent sinusitis
chpo_term: 复发性鼻窦炎
id: HP:0002716
hpo_term: Lymphadenopathy
chpo_term: 淋巴结肿大
id: HP:0004798
hpo_term: Recurrent infection of the gastrointestinal tract
chpo_term: 胃肠道复发性感染
id: HP:0001287
hpo_term: Meningitis
chpo_term: 脑膜炎
id: HP:0100806
hpo_term: Sepsis
chpo_term: 脓毒症