Genre: Information/Explanation

Role of stem cells and differentiated cells in the genesis of squamous cell carcinoma Fiona M Watt CR-UK London Research Institute , London , UK It is widely accepted that oncogenic mutations in stem cells are responsible for driving the development of epidermal tumours . Nevertheless , there is growing evidence that non-dividing cells that are undergoing differentiation can play a role in determining whether an epidermal tumour will progress or regress . In addition , communication between epidermal cells and cells of the immune system can affect tumour formation . In my talk I will discuss some of the mechanisms by which differentiated cells can influence squamous cell carcinoma formation .