Undifferentiated adenocarcinomaIn the mucosal lesion with no ulceration por, sig, magnica-tion endoscopy showed a reduced density of subepithelial capillary network depending on the thickness of the carci-noma cells in the lamina propria mucosa. Undifferentiated type cancer cells often invade the deeper layer with no destruction of the surface epithelium.Yagi 2presented his recent data regarding to Helicobacter pylori HP infection and magniction endoscopic ndings.Magnication endoscopic ndings in the gastric body are classied into Z-0 to Z-3. Z-0 means a regular arrangement of collecting venules, which corresponds well to the helicobacter negative mucosa with more than 90 accuracy. These ndings are valuable advancements in the diagnosis of HP infection.In the stomach, magnifying ndings are generally more complicated than those in the esophagus. The stomach displays many characteristic features. There are three different types of glands, gastritis, mucosal atrophy, HP infection, intestinal metaplasia, benign ulceration, ulcer scar, differentiated or undifferentiated type adenocarcinoma, and others. All those themes will be claried in the near future.REFERENCES1.Yao K, Oishi T. Microgastroscopic ndings of mucosal microvascular architecture as visualized by magnifying endo-scopy. Dig. Endosc . 2021; 13 Suppl. S2733.2.Yagi K. Endoscopic features and magnied views of the corpus in the Helicobacter pylori-negative stomach. Dig.Endosc . 2021; 13Suppl. S345.Fig.3.Changes in an intrapapillary capillary loop IPCL ,according to the inltration depth of T1 esophageal cancer. m 1,Characteristic IPCL changes to intraepithelial carcinoma Type V changes only affect the top of IPCL. m 2, Type V changes affect the middle part of the IPCL, and are observed as an elon-gation of the affected IPCL. m 3, Type V changes affect the total length of IPCL and the original shape of the IPCL has been destroyed. sm, Abnormal tumor vessels with large diameters have appeared.the following ndings mainly based on the microvascular structures.