VitaminD3对裸鼠乳腺癌生长的影响 目录 材料和方法1.1 材料 1.2 方法 2.1Vit D3 对肿瘤大小的影响小鼠接种后饮食正常 2.2Vit D3 对血钙磷的影响Vit D3 组与Vit D3+TAM 2.3细胞周期和细胞凋亡Vit D3 与TAM 皆可使乳腺癌细胞 阻滞于G0/G1 参考文献正文 vitaminD3 breastcancer nudemouse xenograft models 【Abstract】 AIM: VitD3 breastcancer nudemouse xenograft models. METHODS: Each Balb/c nude mouse injectedsubcutaneously humanbreast cancer cell line MCF7. Two thousand units VitD3 micethigh muscle every other day micewere fed mg/kg)every day. Forty experimental mice were randomly pided groups:Vit D3 group, mixedgroup VitD3 tamoxifen,tamoxifen group controlgroup. After tumorvolume serumcalcium phosphoruslevels were assayed. Tumor cells were analyzed flowcytometery detectapoptosis cellcycle. RESULTS: Serum calcium levels VitD3 group were higher than those controlgroup(2.540.05 vs 2.320.09 mmol/L, P