基金资助:
首都医学发展科研基金(2011-4021-03)资助

Relationship between wrist bone mineral density and synovitis, erosion by ultrasonography in female rheumatoid arthritis patients

WANG Yu, GENG Yan, DENG Xue-rong, ZHANG Zhuo-li
(Department of Rheumatology, Peking University First Hospital, Beijing 100034, China)Online:Contact:ZHANG Zhuo-li	E-mail:zhuoli.zhang@126.comSupported by:
Supproted by the Capital Foundation for Medical Research and Development(2011-4021-03).
摘要/Abstract
摘要:
目的:分析类风湿关节炎(rheumatoid arthritis,RA)患者手腕双能X线(dual-energy X-ray absorptiometry,DXA)检查结果,与关节超声影像学评分比较,以确定其与RA关节炎症以及骨侵蚀的相关性。方法:80名女性类风湿关节炎患者采用双能X线法检测非优势手腕部骨密度(bone mineral density, BMD)以及椎体、髋部骨密度,同时检测同侧以及双侧腕关节超声,扫描桡腕关节、中线腕骨间、尺腕关节,并分别记录腕关节滑膜增生、肌腱炎、骨侵蚀等情况,使用彩色多普勒进行关节炎评分。结果:(1)80名女性RA患者中,平均年龄(54.6±13.3) (27.0~80.0)岁,病程48(12~116)个月,体重指数(body mass index, BMI) (23.0±4.0) (14.8~31.2) kg/m2。RA患者腕部BMD低于正常对照[(0.297±0.121)vs.(0.420±0.180) g/cm2,P