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结论:核磁共振成像(MRI)可作为HA义眼台术后血管化程度监测的影像学依据。健康兔眼眶内植入直径12mm的HA义眼台在4周后可达到完全纤维血管化。正常人眼眶内植入直径20mm的HA义眼台在6月后完全纤维血管化。关键词:核磁共振成像(MRI);羟基磷灰石(HA);义眼台;纤维血管化StudiesonthehydroxyapatiteorbitalimplantsfibrovascularizationwithMRIDepartmentofOphthalmology,TongjiHospital,TongjiMedicalCollege,HuazhongUniversityofScienceandTechnologyCandidateDugangSupervisorZhanghongAbstractObjective:ToevaluatetheclinicalworthofapplicationbyinvestigatingthecharacteristicofimaginginrabbitsandhumanhydroxyapatiteorbitalimplantsfibrovascularizationwithMRIandexploringtherelationbetweentimeandvascularizationoftheorbitalimplants.Methods:30NewZealandwhiterabbits’rightorbitswiththesamesurgeryprocedureweredividedrandomlyinto6groups.At1week,andnextsixweekspostoperatively,imaginginrabbitshydroxyapatiteorbitalimplantsfibrovascularizationweremeasuredwithMRI,andVE/VHAwerecalculated.Oneofgroups’hydroxyapatiteorbitalimplantswereobservedbyHEstain.;Whereas,15eyesof15patientswiththesamesurgeryprocedure,at1month,andnextsevenmonthspostoperatively,imaginginhumenhydroxyapatiteorbitalimplantsfibrovascularizationweremeasuredwithMRI,andVE/VHAwerecalculated.Results:Beforethe4thweek,theaverageVE/VHAoftheHAorbitalimplantsinrabbitsaddedupweekly,whiletheaverageVE/VHAof5wand6warealmostthesame,alltheHAorbitalimplantshadaccomplishedfibrovascularizationatthe4thweek;Topatients,beforethe6thmonth,theaverageVE/VHAoftheHAorbitalimplantsaddedupweekly,buttheaverageVE/VHAof6thand7thmontharealmostidentical.Conclusions:MRIisawaytodetecthydroxyapatiteorbitalimplantsfibrovascularization;12mmHAorbitalimplantsinrabbitshadaccomplishedfibrovascularizationatthe4thweek;Topatient,20mmHAorbitalimplantshadaccomplishedfibrovascularizationatthe6thmonth.【Keywords】MRI;hydroxyapatite;artificialeye;fibrovascularization