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Science June 25, 2009 DOI: 10.1126/science.1174447
A Gene Network Regulating Lysosomal Biogenesis and Function
Marco Sardiello 1, Michela Palmieri 1, Alberto di Ronza 1, Diego Luis Medina 1, Marta Valenza 2, Vincenzo Alessandro Gennarino 1, Chiara Di Malta 1, Francesca Donaudy 1, Valerio Embrione 1, Roman S. Polishchuk 3, Sandro Banfi 1, Giancarlo Parenti 4, Elena Cattaneo 2, Andrea Ballabio 4*
1 Telethon Institute of Genetics and Medicine (TIGEM), Via P. Castellino 111, 80131 Naples, Italy.
2 Department of Pharmacological Sciences and Center for Stem Cell Research, University. of Milan, Via Balzaretti 9, 20133 Milan, Italy.
3 Telethon Electron Microscopy Core Facility, Department of Cell Biology and Oncology, Consorzio Mario Negri Sud, I-66030 Santa Maria Imbaro, Chieti, Italy.
4 Telethon Institute of Genetics and Medicine (TIGEM), Via P. Castellino 111, 80131 Naples, Italy.; Department of Pediatrics, Federico II University, Via S. Pan