相对于植物,像大肠杆菌、酵母、链霉菌等微生物具有生长迅速、培养成本低和易于大规模发酵等优点;一旦部分阐明或完全阐明植物来源的二萜类化合物生物合成的相关酶,我们就可以通过合成生物学手段,利用微生物作为底盘细胞,产生植物来源的活性二萜化合物或其中间体,解决药用植物资源稀缺、来源受限、提取工艺复杂等问题。
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