关键词: 肺结核; 初治涂阳 ; 胸腺肽; 左氟沙星中 图 分类号: R521文献标识码: B文章编号: 1672-3619(2013)06-0768-03Analysis of clinical efficacy of 2HRZE /4HR anti-TB combined withthymosin and levofloxacin in patients with smear positive tuberculosisZHOU Jia-jie, LIU Wei-ling(The Ninth People′s Hospital ofNanning, Guangxi, Nanning 530409, China)Abstract:ObjectiveTo evaluate clinical efficacy of 2HRZE /4HR anti-TB combined with thymosin and levofloxacin inpatients with smear positive tuberculosis.Methods104 cases of smear positive TB patients retreating in our hospital wererandomly selected and allocated to observation group and control group. The observation group was treated with 2HRZE /4HRanti-TB combined with thymosin and levofloxacin, while the control group was treated with 2HRZE /4HR. The sputum negativeconversion rate,focusing absorption rate,adverse reaction of the treatment,and treatment effect in the two groups wereanalyzed. ResultsIn observation group,sputum negative conversion rates in 2,4 and 6 month were 47 (90.38%),49(94.23%) and 50(96.15%), respectively, and were significantly higher than those of control group (P<0.05). The observationgroup′s absorption rate was also significantly higher than that of the control group (P<0.05). The total cure rate and absorptionrate in the observation group was 96.15% and 88.46%, significantly higher than control group (P<0.05). ConclusionThesputum negative conversion rate,focusing absorption rate and curative effect in patients with smear positive tuberculosis wereimproved by 2HRZE /4HR anti-TB combined with thymosin and levofloxacin. It is worthy to be used in clinical.Key words: pulmonary tuberculosis;smear positive tuberculosis;thymosin; levofloxacin· 临床研究论著·768··C M Y K 热带医学杂志