致谢:本项目得到国家973项目( G2000048010) 和国家自然科学基金委( 20133030) 的支持。参考文献[ 1] J essop,P J .:Ikari ya,T.:Noyori ,R.Sci ence1995,269,1065.[ 2] gckert,C A.:Knutson,B.L.:Debenedetti ,GP Nature1996,383,313.[ 3] Arend,M.:Westermann,B.:Ri sch,N.Angew.Chem.Int.Ed.1998,37,1044[ 4] Trost,B.M.:Terrel l ,LR.J .Am.Chem.Soc.2003,125,338. Three- componentManni ch Reacti on ofBenzal dehyde,Ani l i ne,and Acetophenonei nSupercri ti calC02Yanhong Chang,Buxi ng Han,Tao J i ang,Li ang Gao,Wei ze Wu,Zhi mi n Li u,Hai xai ngGaoCenter for Mol ecul arSci ence,Insti tuteofChemi stry, Chi nese AcademyofSci ences,Bei j i ng 100080,Chi naAbstract:Supercri ti calcarbon di oxi de( SC C02) i s an effecti ve sol ventforthree- componentManni ch reacti onofbenzal dehyde,ani l i ne.and acetophenone catal yzedbytri fl uoaceti c aci d,andyi el d upto 95%can beachi eved.Furthermore,thereacti on can al so takepl acei n the absence ofany catal ystas SCC02i s used as thesol ventKey words:Supe rcri ti calcarbon di oxi de,Manni chreacti on,