The Infructescence of Platycarya strobilacea is the dry Infructescence of Platycarya Strobilacea, which is a traditional medicinal plant in China. It has functions of clearing up heat and detoxification, dispelling wind and relieving pain, activating blood circulation and removing stasis, clearing orifices and expelling pus. It is commonly used by people to treat various complications caused by acute and chronic rhinitis, sinusitis and acute upper respiratory tract infection, and is a kind of Chinese medicine with excellent development space and utilization value and has broad market prospects. There are many chemical constituents in the Infructescence of Platycarya strobilacea, including volatile oils, Phenols, flavonoids, terpenoids, carbohydrates and other compounds. Among them, volatile oils are the most abundant, but lack of correlated activity studies. Phenolic compounds, flavonoids and terpenoids are the main pharmacogenetics constituents. However, few of these compounds have been isolated and identified. Modern pharmacological studies have shown that the Infructescence of Platycarya Strobilacea has many pharmacological activities, such as anti-tumor, anti-virus, anti-inflammatory and bacteriostasis, anti-aging, growth promotion, hypotension and sedation, but the existing studies mainly focus on anti-virus, anti-inflammatory and bacteriostasis, anti-tumor effects, and other activities have not been further explored. In the future, the chemical constituents and pharmacological activities of the Infructescence of Platycarya Strobilacea should be studied in depth, and its mechanism should be further clarified so that it can be more fully and reasonably applied. By consulting domestic and foreign literature in recent years in CNKI, Vip database, Wanfang date, PubMed and other databases. The chemical constituents, pharmacological effects and clinical application of the Infructescence of Platycarya Strobilacea were summarized and expounded its research progress in order to provide theoretical reference for further research and further development and application of the Infructescence of Platycarya Strobilacea. [Key words] Infructescence of Platycarya Strobilacea; volatile oils; phenol; flavonoids; antitumor; antiviral; anti-inflammatory and bacteriostatic 网络首发时间:2019-07-04 09:27:42网络首发地址:http://kns.cnki.net/kcms/detail/11.3495.r.20190701.1648.006.html 化香树果序是胡桃科化香树属植物化香树的干燥果序,原植物化香树收录于《植物名实图考》中,在我国长江以南各省及陕西、甘肃、河南等地均有分布,国外也有少数存在。其味辛,性温;功能顺气,清热解毒,祛风化痰,通窍止痛,活血化淤、消肿排脓、燥湿杀虫,主治鼻渊、风毒、痈肿、疰痛、疥癣、内伤胸胀、头腹疼痛、筋骨疼痛等症 [1-3] 。化香树果序多数出产于我国西北、华东、华中、华南等地,其中在秦巴山区最为优产,民间一般将其煎汤用于治疗各种鼻炎、鼻窦炎、伤风鼻塞以及急性上呼吸道感染等症,效果显著 [4-6] 。化香树果序中含有挥发油类、酚类、黄酮类、萜类、糖类等化学成分 [7-8] ,药理研究表明,其具有抗炎、抗病毒、抑菌等多种药理作用 [9] 。近年来,有关化香树果序的研究逐渐深入,其药理作用机制逐渐明确,但未见有系统报道化香树果序研究进展的文章。因此,本文对国内外有关化香树果序化学成分、药理作用的研究进行系统综述,以期为化香树果序的进一步开发利用和临床研究提供科学依据。 1 化学成分 1.1 挥发油 目前,已知的从化香树果序中分离鉴定得到的挥发油成分共有 52 个,其中包括倍半萜类、长链烃及脂肪酸类和脂肪酰胺类化合物,主要成分是倍半萜类化合物,此类成分具有抗肿瘤、抑菌消炎、抗病毒、抗神经毒性、免疫抑制、降血脂等生物活性,与化香树果序功效