The specific lyric "funk you up" is a stock phrase in the genre, probably originating with Clinton's influential bandParliament Funkadelic, which used variations on it in several of their songs (including one that includes the phrase "funked up" in the title). It's a play on the phrase "f* you up," primarily meaning to beat someone up, and has the connotation that the music is going to physically attack you, with secondary connotations of sexual satisfaction.
Source:lyrics - The meaning of "Uptown Funk"
在stack exchange上看到这个答案觉得很有道理。