1. IPCL shows characteristic changes in carcinoma in situ . Those include weaving, dilatation, irregular caliber and a different shape in each IPCL. According to the grade of IPCL changes, target epithelium can be diagnosed from normal mucosa T ype I to carcinoma Type V Fig.2. By the uation of IPCL changes, inltration depth of the cancerous lesion can also be assessed. In the m 1lesion, characteristic changes in are observed Fig.2. In the m 2lesion the elongation of affected IPCL is observed, and in the m 3lesion destruction of IPCL becomes much more obvious. In the sm cancer, almost total IPCL has been destructed and a novel tumor vessel often appears Fig.3. In the esophagus, the usefulness of magnify-ing endoscopy is gradually but steadily recognized.Digestive Endoscopy 2021 13Suppl., S40S41SESSION 2 MODERATORS COMMENTMAGNIFICATION ENDOSCOPY IN THE ESOPHAGUS AND STOMACHHaruhiro InoueShowa University, Northern Yokohama Hospital, Yokohama, JapanCorrespondence Haruhiro Inoue, Assistant Professor Chief of Upper Gastrointestinal Endoscopy and Surgery, Showa University,Northern Yokohama Hospital, Chuo 35-1, Tsuzuki-ku, Yokohama 224-2503, Japan. Email haru.inouemed.showa-u.ac.jpFig.