【关键词】 乙型肝炎肝硬化糖代谢异常胰岛 β 细胞The analysis of pancreas islet β-cells function index of the patients of hepatitis B cirrhosis concomitant withabnormal glucose metabolismLv Minglei, Liu Qin,Cheng Wenfang. The Infectious Diseases Hospital of Xin Xiang City, Xinxiang,Henan453000【Abstract】 ObjectiveTo explore the pathogenesis and characteristic of the patients of Hepatitis B cirrhosis concomitant with abnormal glucose metabolism. MethodsAccording to oral glucose tolerance test result, 90 patients of Hepatitis B cirrhosis were divided into normal glucose tolerance group, impaired glucose tolerance group and diabetes group. Each group had 30 cases, at the same time 30 cases of healthy persons were taken as control group, to observe and compare their blood sugar, insulin,C petide release and pancreas islet β -cells function index. ResultsCompared with control group, insulin level of the patients of normal glucose tolerance distinctly increased during empty stomach and 2 hours after meal, P<0.01;compared with normal glucose tolerance group, blood level and insulin level of the patients of impaired glucose tolerance group clearly increased 2 hours after meal, P<0.05;compared with impaired glucose tolerance group, blood level of diabetic patients distinctly increased during empty stomach and 2 hours after meal, their insulin lever distinctly decreased, C petide level and pancreas islet β -cells function index distinctly decreased respectively, P<0.05. ConclusionWhen glucose tolerance of the patients of Hepatitis B cirrhosis was normal or impaired, their pancreas islet β -cells still had a certain degree of secretion. When Diabetes was complicated by, their pancreas islet β -cells secretion distinctly decreased. 【Key Words】 Hepatitis B Cirrhosis Abnormal glucose metabolis Pancreas islet β -cell 乙型肝炎肝硬化伴糖代谢异常患者胰岛 β 细胞功能特点分析吕明磊刘琴程文芳(新乡市传染病医院,河南 新乡 453000)