[中图分类号] R916. 693 [文献标志码] A [文章编号] 2095 -3593(2019)04 -0289 -05Experimental Study on Bacteriostasis and Antiviral of Xiaoer Feire Kechuan ParticlesLI Pei-hu, LIU Quan-guo, WU Yu-qiang ∗(Hainan HuLuwa Pharmaceutical Group Co. , Ltd. , Hainan Haikou 570311, China)[Abstract] Objective:To investigate the bacteriostatic and antiviral effects of Xiaoer Feire Kechuan Particles. Methods:In vivo antivi-ral test and in vivo and in vitro bacteriostatic test were used to investigate the effect of drugs. Results:After 7 days of continuous adminis-tration, Xiaoer Feire Kechuan Particles 7. 0 and 14. 0g raw drug·kg-1dose group had obvious protective effect on influenza A/ PR8/34virus and influenza B virus infection, showing obvious antiviral effect;In vitro bacteriostatic test showed that:Xiaoer Feire Kechuan Parti-cles to the above standard, staphylococcus aureus, escherichia coli, bacillus subtilis, e. coli clinical isolated, pneumonic diplococcus,staphylococcus aureus, onion false single spore bacilli, epidermis staphylococcus aureus, generation all have certain bacteriostatic action,bacteriostasis circle range (10. 5 ~14. 5) mm; In vivo bacteriostatic test, continuous administration for 7 days, the mice infected withstaphylococcus aureus and pneumococci had obvious protective effect, showing obvious antibacterial effect. Conclusion:Xiaoer FeireKechuan Particles have obvious antibacterial and antiviral effects.