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Exhibit 10.10

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First Horizon Pharmaceutical Corporation
Mr. Patrick Fourteau
6195 Shiloh Road

Alpharetta, GA 30005

USA

    29 October 2004
Zie

Renewal of the Term of the Distribution Agreement between First Horizon
Pharmaceutical Corporation and Pohl-Boskamp effective February 1, 2000

Dear Mr. Fourteau,

As mutually agreed during the meeting in Hohenlockstedt on October 6, 2004 we
herewith confirm that the Distribution Agreement between First Horizon and
Pohl-Boskamp will be renewed for an additional five-year-period effective
February 1, 2005. It will be renewed automatically for two-year-periods each
unless it is cancelled with a six-month-notice by one of the contractual parties
before the end of the five-year-period or respectively before each of the
following two-year periods.

The parties have further agreed to abstain from defining new minimum sales.

All other stipulations of the Agreement shall remain unchanged.

Please have First Horizon execute below to signify its approval to the above and
return one copy of it by return mail.

Yours sincerely,

POHL BOSKAMP

/s/  THOMAS HOPPNER      

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Dr. Thomas Hoppner
Senior Director
Business Unit Export   /s/  HEIKE JÖRN      

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Heike Jörn
Senior Director
Legal Department
/s/  PATRICK FOURTEAU      

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Patrick Fourteau
President &
Chief Operating Officer
 
/s/  RALPH JORDAN      

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Ralph Jordan
Senior Director
of Business Affairs

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Exhibit 10.10