Exhibit 10.41

 

SUBSCRIPTION AGREEMENT

 

This SUBSCRIPTION AGREEMENT (this “Agreement”) is made as of the latest date set
forth on the signature page hereof between Fennec Pharmaceuticals Inc. (the
“Company”) and the undersigned (the “Subscriber”).

 

WITNESSETH:

 

WHEREAS the Company desires to offer and issue for sale on a private placement
basis (the “Offering”) of (i) 1,092,828 common shares in the capital of the
Company (the “First Closing Shares”), anticipated to occur on or about April 8,
2016 or such other date as the Company and the Subscriber may agree (the “First
Closing Date”) and (ii) 1,538,751 common shares in the capital of the Company
(the “Second Closing Shares”, with the sum of First Closing Shares and Second
Closing Shares being referred to as the “Shares”), anticipated to occur within
two (2) business days of receipt of certain regulatory approval or such other
date as the Company and the Subscriber may agree (the “Second Closing Date”,
which together with the First Closing Date shall constitute a “Closing”, as the
context requires), each at a price per Share of USD$1.90 and representing an
aggregate purchase price of $5,000,000.10 (the “Purchase Price”). A summary of
the terms of the Offering is set forth in Schedule “A” to this Agreement. Such
summary is qualified in its entirety by the terms and conditions set forth in
this Agreement; and

 

WHEREAS unless otherwise stated, all dollar amounts in this Agreement refer to
United States Dollars; and

 

WHEREAS, the Subscriber desires to purchase Shares on the terms and conditions
hereinafter set forth.

 

NOW, THEREFORE, in consideration of the premises and the mutual representations
and covenants hereinafter set forth, the parties hereto do hereby agree as
follows:

 

I.           SUBSCRIPTION FOR SHARES AND REPRESENTATIONS BY SUBSCRIBER

 

1.1           Subject to the terms and conditions hereinafter set forth, the
Subscriber hereby irrevocably purchases for itself and agrees to purchase from
the Company, and the Company agrees to sell to the Subscriber, the Shares for an
aggregate purchase price equal to the Purchase Price. The Purchase Price is
payable by wire transfer of immediately available funds at the time of entering
into this Agreement to an account designated by LaBarge Weinstein LLP, counsel
to the Company (“Company Counsel”), to be held in escrow and shall be released
at each Closing (as defined herein) by Company Counsel to an account designated
by the Company in accordance with the terms and conditions of this Agreement. In
the event that each Closing does not occur as contemplated by the terms of this
Agreement, Company Counsel shall return the applicable Purchase Price held in
escrow to the Subscriber by means of wire transfer of immediately available
funds within two (2) business days of such determination.

 

1.2           The Subscriber hereby warrants and represents that it recognizes
that the purchase of the Shares involves a high degree of risk including, but
not limited to, the following: (a) an investment in the Company is highly
speculative and only investors who can afford the loss of their entire
investment should consider investing in the Company and the Shares; (b) the
Subscriber may not be able to liquidate its investment; and (c) transferability
of the Shares is limited.

 

   

 

 

1.3           The Subscriber represents that it (i) is an “accredited investor”
as such term is defined in Rule 501(a) of Regulation D promulgated under the
Securities Act of 1933, as amended (the “Act”), as indicated by the Subscriber’s
responses to the questions contained in Article IX hereof, and by reason of its
business and financial experience and the business and financial experience of
those persons it may have retained to advise it with respect to its investment
in the Shares it, together with such advisors, has such knowledge,
sophistication and experience in business and financial matters that it is
capable of evaluating the merits and risks of the prospective investment; (ii)
is an “accredited investor” as such term is defined in National Instrument
45-106 – Prospectus Exemptions, of the Canadian Securities Administrators and
the Subscriber has completed the Accredited Investor Certificate attached hereto
as Schedule “C” and (iii) complies with the requirements of all applicable
securities laws in its jurisdiction that is other than the United States and
Canada (the “International Jurisdiction”) and has completed the Accredited
Investor Certificate attached hereto as Schedule “D”.

 

1.4           The Subscriber hereby acknowledges and represents that: (a) the
Subscriber has knowledge and experience in business and financial matters, prior
investment experience, including investment in securities that are unregistered,
or the Subscriber, at its own risk and expense, has employed the services of a
“purchaser representative” (as defined in Rule 501(h) of Regulation D), attorney
and/or accountant to read all of the documents furnished or made available by
the Company to the Subscriber to evaluate the merits and risks of such an
investment on the Subscriber’s behalf; (b) the Subscriber recognizes the highly
speculative nature of this investment; and (c) the Subscriber is able to bear
the loss of its entire investment.

 

1.5           The Subscriber represents that (i) the Subscriber was contacted
regarding the sale of the Shares by the Company, or a Company agent, with whom
the Subscriber had a prior substantial pre-existing relationship and (ii) no
Shares were offered or sold to it by means of any form of general solicitation
or general advertising, and in connection therewith, the Subscriber did not
receive any general solicitation or general advertising including, but not
limited to: (A) any advertisement, article, notice or other communication
published in any newspaper, magazine or similar media or broadcast over
television or radio, whether closed circuit, or generally available; or (B)
through attendance at any seminar meeting or industry investor conference whose
attendees were invited by any general solicitation or general advertising.

 

1.6           The Subscriber hereby acknowledges that the Offering has not been
reviewed by the United States Securities and Exchange Commission (the “SEC”) nor
any U.S. state or Canadian provincial securities regulatory authority
(“Securities Regulatory Authority”) as the Offering is intended to be exempt
from the registration requirements of Section 5 of the Act, pursuant to
Regulation D thereunder and from the registration requirements of applicable
state “blue sky” securities laws or regulations. The Subscriber understands that
the Shares have not been registered under the Act or under any U.S. state or
Canadian provincial securities or “blue sky” laws or regulations by reason of a
claimed exemption that depends, in part, upon the Subscriber’s investment
intention and agreement not to sell, pledge, assign or otherwise transfer or
dispose of the Shares unless they are registered under the Act and under any
applicable state securities or “blue sky” laws or regulations or unless an
exemption from such registration is available, subject to Section 1.10 herein.
Without limiting the foregoing, the Company acknowledges and agrees that a
Subscriber may from time to time pledge pursuant to a bona fide margin agreement
with a registered broker-dealer or grant a security interest in some or all of
the Shares to a financial institution that is an “accredited investor” as
defined in Rule 501(a) under Regulation D and who agrees to be bound by the
provisions of this Agreement and, if required under the terms of such
arrangement, such Subscriber may transfer pledged or secured Shares to the
pledgees or secured parties. Such a pledge or transfer would not be subject to
approval of the Company and no legal opinion of legal counsel of the pledgee,
secured party or pledgor shall be required in connection therewith. Further, no
notice shall be required of such pledge. At the Subscriber’s expense, the
Company will execute and deliver such reasonable documentation as a pledgee or
secured party of the Subscriber may reasonably request in connection with a
pledge or transfer of the Shares.

 

 -2- 

 

 

1.7           The Subscriber hereby represents that the Subscriber is purchasing
the Shares for the Subscriber’s own account and not with a view toward the
resale or distribution to others. The Subscriber, if an entity, further
represents that it was not formed for the purpose of purchasing the Shares.

 

1.8           The Subscriber understands that Rule 144 (“Rule 144”) promulgated
under the Act requires for non-affiliates, among other conditions, a one (1)
year holding period prior to the resale in the United States of securities of an
issuer that is not a reporting issuer under the Securities Exchange Act of 1934,
as amended, acquired in a non-public offering without having to satisfy the
registration requirements under the Act. The Subscriber understands and hereby
acknowledges that except as set forth herein the Company is under no obligation
to register any of the Shares under the Act or any state securities or “blue
sky” laws.

 

1.9           The Subscriber further understands and agrees that it shall not
sell the Shares to a purchaser in any province of Canada at any time within the
four (4) month period following the respective date of their issuance and any
subsequent purchaser outside of Canada before the end of that period must agree
to comply with this restriction for the remainder of such period. The Subscriber
further agrees that if it decides to offer, sell or otherwise transfer, pledge
or hypothecate all or any part of the Shares, it will not offer, sell or
otherwise transfer, pledge or hypothecate any of such Shares (other than
pursuant to an effective registration statement under the Act), directly or
indirectly unless an offer and sale or other disposition is:

 

(a)            made in accordance with an effective registration statement under
the Act covering such disposition; or

 

(b)           to the Company; or

 

(c)           made outside the United States in accordance with the requirements
of Rule 904 of Regulation S under the Act; or

 

(d)           made in a transaction that does not require registration under the
Act or any applicable United States state laws, rules and regulations governing
the offer and sale of securities, and it has theretofore furnished to the
Company an opinion of counsel to that effect; provided, that no opinion shall be
required for any sale pursuant to Rule 144, or pursuant to any bona fide pledge
in connection with a margin account.         

 

1.10         The Subscriber consents to the placement of a legend on any
certificate or other document evidencing the Shares indicating that such Shares
have not been registered under the Act or any state securities or “blue sky”
laws and setting forth or referring to the restrictions on transferability and
sale thereof contained in this Agreement. The Subscriber is aware that the
Company will make a notation in its appropriate records with respect to the
restrictions on the transferability of such Shares. The legend to be placed on
each certificate shall be in form substantially similar to the following:

 

UNLESS PERMITTED UNDER SECURITIES LEGISLATION, THE HOLDER OF THIS SECURITY MUST
NOT TRADE THE SECURITY BEFORE THE DATE THAT IS 4 MONTHS AND A DAY AFTER APRIL 8,
2016.

 

 -3- 

 

 

THE SECURITIES REPRESENTED BY THIS CERTIFICATE ARE LISTED ON THE TORONTO STOCK
EXCHANGE (“TSX”); HOWEVER, THE SAID SECURITIES CANNOT BE TRADED THROUGH THE
FACILITIES OF TSX SINCE THEY ARE NOT FREELY TRANSFERABLE, AND CONSEQUENTLY ANY
CERTIFICATE REPRESENTING SUCH SECURITIES IS NOT “GOOD DELIVERY” IN SETTLEMENT OF
TRANSACTIONS ON TSX.

 

THE SECURITIES REPRESENTED HEREBY HAVE NOT BEEN REGISTERED UNDER THE UNITED
STATES SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”). THE HOLDER HEREOF, BY
PURCHASING SUCH SECURITIES, AGREES FOR THE BENEFIT OF THE ISSUER THAT SUCH
SECURITIES MAY BE OFFERED, SOLD OR OTHERWISE TRANSFERRED ONLY (A) TO THE ISSUER,
(B) OUTSIDE THE UNITED STATES IN ACCORDANCE WITH RULE 904 OF REGULATION S UNDER
THE ACT, OR (C) IN ACCORDANCE WITH AN EFFECTIVE REGISTRATION STATEMENT OR
PURSUANT TO ANOTHER EXEMPTION FROM REGISTRATION AFTER PROVIDING A REASONABLY
SATISFACTORY LEGAL OPINION TO THE ISSUER.

 

Provided that if the Shares are being sold pursuant to Section 1.9(c) above, in
the case of a resale to a purchaser in Canada, following the date which is four
(4) months and a day after the date of issuance to the Subscriber, the Company
covenants and represents that the legend may be removed by providing a
declaration to the transfer agent for the Shares of the Company substantially as
attached hereto as Schedule “B” (or as the Company may prescribe from time to
time) upon the sale of the Shares by the Subscriber.

 

1.11         The Subscriber understands that the Company, at its sole
discretion, reserves the unrestricted right, without further documentation or
agreement on the part of the Subscriber, to reject or limit any purchase, to
accept purchases for fractional Shares and to close the Offering to the
Subscriber at any time and that the Company will issue stop transfer
instructions to its transfer agent with respect to such Shares.

 

1.12         The Subscriber hereby represents that the address of the Subscriber
furnished by Subscriber on the signature page hereof is the Subscriber’s
principal residence if the Subscriber is an individual or its principal business
address if it is a corporation or other entity and that Subscriber is not
resident in any province of Canada. If the Subscriber is resident outside of the
United States, the Subscriber hereby represents that the Subscriber is resident
in the International Jurisdiction specified in the address set out on
Subscriber’s signature page to this Agreement and that:

 

(a)           the Subscriber is knowledgeable of, or has been independently
advised as to, the applicable securities laws of the International Jurisdiction
which would apply to this subscription, if there are any;

 

(b)           the securities laws of the International Jurisdiction applicable
to the Subscriber do not require the Company to file a prospectus or similar
document or to register the Shares or to make any filings or seek any approvals
of any kind whatsoever in respect of the sale of the Shares to the Subscriber
from any regulatory authority in the International Jurisdiction;

 

(c)            the delivery of this Agreement by the Company and the Subscriber
and the issuance of the Shares to the Subscriber complies with all applicable
securities laws of the International Jurisdiction and will not cause the Company
to become subject to any disclosure, prospectus, registration or reporting
requirements under any such securities laws; and

 

 -4- 

 

 

(d)           the Subscriber will, if requested by the Company, deliver to the
Company a certificate or opinion of local counsel from the International
Jurisdiction which will confirm the matters referred to in subparagraphs (b) and
(c) above to the satisfaction of the Company, acting reasonably.

 

1.13         The Subscriber represents that the Subscriber has full power and
authority (corporate, statutory and otherwise) to execute and deliver this
Agreement and to purchase the Shares. This Agreement constitutes the legal,
valid and binding obligation of the Subscriber, enforceable against the
Subscriber in accordance with its terms, subject to laws of general application
relating to bankruptcy, insolvency and the relief of debtors and rules of law
governing specific performance, injunctive relief or other equitable remedies,
and to limitations of public policy.

 

1.14         If the Subscriber is a corporation, partnership, limited liability
company, trust, employee benefit plan, individual retirement account, Keogh
Plan, or other tax-exempt entity, it is authorized and qualified to invest in
the Company and the person signing this Agreement on behalf of such entity has
been duly authorized by such entity to do so.

 

1.15         The Subscriber is not a Registered Representative of a Financial
Industry Regulatory Authority (“FINRA”) member firm.

 

1.16         

(a)           The Subscriber agrees not to issue any public statement with
respect to the Subscriber’s investment or proposed investment in the Company or
the terms of any agreement or covenant between them and the Company without the
Company’s prior written consent (which consent shall not be unreasonably
withheld, conditioned or delayed), except such disclosures as may be required
under applicable law or under any applicable order, rule or regulation.

 

(b)           The Subscriber acknowledges that this Agreement requires the
Subscriber to provide certain personal information to the Company. Such
information is being collected by the Company for the purposes of completing the
Offering, which includes, without limitation, determining the Subscriber's
eligibility to purchase the Shares under applicable securities laws, preparing
and registering certificates representing the Shares to be issued to the
Subscriber and completing filings required by any Securities Regulatory
Authority. The Subscriber’s personal information may be disclosed by the Company
to: (a) any applicable Securities Regulatory Authority; (b) the Company's
registrar and transfer agent; (c) Canada Revenue Agency; (d) any applicable
stock exchange or over-the-counter market (including the TSX); and (e) the
Company’s advisors, including legal counsel, and may be included in record books
in connection with the Offering. By executing this Agreement, the Subscriber is
deemed to be consenting to the foregoing collection, use and disclosure of the
Subscriber's personal information.

 

(c)           The Subscriber consents to the filing of copies or originals of
any of the Subscriber’s documents described in Section 1.16(b) hereof as may be
required to be filed with any Securities Regulatory Authority in connection with
the transactions contemplated hereby.

 

(d)          If the Subscriber is a resident of or otherwise subject to
applicable securities laws of Ontario, the Subscriber acknowledges that it has
been notified by the Company (a) of the delivery to the Ontario Securities
Commission (the “OSC”) of the full name, residential address and telephone
number of the Subscriber, the number and type of securities purchased, the total
purchase price, the exemption relied upon and the date of distribution; (b) that
this information is being collected indirectly by the OSC under the authority
granted to it under applicable securities laws; (c) that this information is
being collected for the purposes of the administration and enforcement of the
Securities Law of Ontario; and (d) that the Administrative Assistant to the
Director of Corporate Finance can be contacted at Suite 1903, Box 55, 20 Queen
Street West, Toronto, Ontario M5H 3S8 or at (416) 593-8086 regarding any
questions about the OSC’s indirect collection of this information and further
acknowledges that it has authorized the indirect collection of this information
by the OSC.

 

 -5- 

 

 

(e)          The Subscriber represents and warrants that the funds representing
the aggregate Purchase Price which will be paid by the Subscriber to the Company
for the Shares hereby subscribed for will not represent proceeds of crime for
the purposes of the Proceeds of Crime (Money Laundering) and Terrorist Financing
Act (Canada) (the “PCMLA”) and the Subscriber acknowledges that the Company may
in the future be required by law to disclose the Subscriber's name and other
information relating to this Agreement and the Subscriber’s subscription
hereunder, on a confidential basis, pursuant to the PCMLA. To the best of its
knowledge (a) none of the subscription funds to be provided by the Subscriber
(i) have been or will be derived from or related to any activity that is deemed
criminal under the law of Canada, the United States of America, or any other
jurisdiction, or (ii) are being tendered on behalf of a person who has not been
identified to the Subscriber, and (b) it shall promptly notify the Company if
the Subscriber discovers that any of such representations ceases to be true, and
to provide the Company with appropriate information in connection therewith.

 

1.17         Except for Four Partners Advisory SIM S.p.A., the Subscriber
represents and warrants that it has not engaged, consented to or authorized any
broker, finder or intermediary to act on its behalf, directly or indirectly, as
a broker, finder or intermediary in connection with the transactions
contemplated by this Agreement. The Subscriber hereby agrees to indemnify and
hold harmless the Company from and against all fees, commissions or other
payments owing to any such person or firm acting on behalf of the Subscriber
hereunder.

 

1.18         The Subscriber agrees to hold the Company and its directors,
officers, employees, affiliates, controlling persons and agents and their
respective heirs, representatives, successors and assigns harmless and to
indemnify them against all liabilities, costs and expenses incurred by them as a
result of (a) any sale or distribution of the Shares by the Subscriber in
violation of the Act or any applicable state securities or “blue sky” laws; or
(b) any false representation or warranty or any breach or failure by the
Subscriber to comply with any covenant made by the Subscriber in this Agreement
(including the Confidential Investor Questionnaire contained in Article IX
herein) or any other document furnished by the Subscriber to any of the
foregoing in connection with this transaction.

 

1.19         The Subscriber understands, acknowledges and agrees with the
Company that, except as otherwise set forth herein, the subscription hereunder
is irrevocable by the Subscriber, that, except as required by law, the
Subscriber is not entitled to cancel, terminate or revoke this Agreement or any
agreements of the Subscriber hereunder and that this Agreement and such other
agreements shall survive the death or disability of the Subscriber and shall be
binding upon and inure to the benefit of the parties and their heirs, executors,
administrators, successors, legal representatives and permitted assigns. If the
Subscriber is more than one person, the obligations of the Subscriber hereunder
shall be joint and several and the agreements, representations, warranties and
acknowledgments herein contained shall be deemed to be made by and be binding
upon each such person and his/her heirs, executors, administrators, successors,
legal representatives and permitted assigns.

 

1.20         The Subscriber understands, acknowledges and agrees with the
Company that the Offering is intended to be exempt from registration under the
Act pursuant to the provisions of Regulation D thereunder, which is in part
dependent upon the truth, completeness and accuracy of the representations made
by the Subscriber herein.

 

 -6- 

 

 

1.21         The Subscriber acknowledges that the information contained in this
Agreement or otherwise made available to the Subscriber is confidential and
non-public and agrees that all such information shall be kept in confidence by
the Subscriber and neither used by the Subscriber for the Subscriber’s personal
benefit (other than in connection with this Agreement, as supplemented) nor
disclosed to any third party for any reason, unless such disclosure is required
by applicable law or a court judgment, order or decree, notwithstanding that the
Subscriber’s subscription may not be accepted by the Company; provided, however,
that this obligation shall not apply to any such information that (i) is part of
the public knowledge or literature and readily accessible at the date hereof,
(ii) becomes part of the public knowledge or literature and readily accessible
by publication (except as a result of a breach of this provision) or (iii) is
received from third parties (except third parties who disclose such information
in violation of any confidentiality agreements or obligations, including,
without limitation, any subscription or other similar agreement entered into
with the Company).

 

1.22         The Subscriber understands, acknowledges and agrees with the
Company that: (a) the Company may terminate the Offering or reject any
subscription at any time in its sole discretion and the execution of this
Agreement by the Subscriber or solicitation of the investment contemplated
hereby shall create no obligation on the part of the Company to accept any
subscription or complete the Offering; (b) no federal, provincial or state
agency or authority has made any finding or determination as to the accuracy or
adequacy of the Offering documents or as to the fairness of the terms of the
Offering nor any recommendation or endorsement of the Shares (any representation
to the contrary is a criminal offense); and (c) in making an investment
decision, the Subscriber must rely on its own examination of the Company and the
terms of the Offering, including the merits and risks involved.         

 

II.          REPRESENTATIONS AND WARRANTIES OF THE COMPANY

 

In the event that the Company accepts the Subscriber’s subscription of Shares
hereunder, the Company hereby represents and warrants to the Subscriber that:

 

2.1           Organization, Good Standing and Qualification. The Company is a
corporation duly organized, validly existing and in good standing under the laws
of British Columbia and has full corporate power and authority to own, lease and
operate its property and assets, and to conduct its business as now conducted.
The Company has conducted and is conducting its business in compliance in all
material respects with all applicable laws, rules and regulations of the
jurisdictions in which it carries on business.

 

2.2           Capitalization and Voting Rights. The Company is authorized to
issue an unlimited number of common shares in the capital of the Company (the
“Common Shares”). As of March 31, 2016, the Company had 11,006,988 Common Shares
issued and outstanding, and all issued and outstanding shares of the Company are
validly issued, fully paid and non-assessable. As of March 31, 2016, the Company
had: (i) warrants to purchase a total of 1,749,464 Common Shares outstanding and
(ii) 2,417,255 options outstanding. Other than as set forth in the preceding
sentence, there are no outstanding options, warrants, agreements, convertible
securities, preemptive rights or other rights to subscribe for or to purchase
any shares in the capital stock of the Company. Except as required by law, there
are no restrictions upon the voting or transfer of any of the shares in the
capital stock of the Company pursuant to the Company’s notice of articles as
amended to date or any agreement or other instruments to which the Company is a
party or by which the Company is bound.

 

 -7- 

 

 

2.3           Authorization; Enforceability. The Company has all corporate
right, power and authority to enter into this Agreement and to consummate the
transactions contemplated hereby. All corporate action on the part of the
Company and its directors necessary for the (i) authorization, execution,
delivery and performance of this Agreement by the Company; and
(ii) authorization, sale, issuance and delivery of the Shares contemplated
hereby and the performance of the Company’s obligations hereunder has been taken
or will be taken prior to the applicable Closing (in accordance with Section 3.1
or Section 3.3, as the case may be). This Agreement has been duly executed and
delivered by the Company and constitutes a legal, valid and binding obligation
of the Company, enforceable against the Company in accordance with its terms,
subject to laws of general application relating to bankruptcy, insolvency and
the relief of debtors and rules of law governing specific performance,
injunctive relief or other equitable remedies, and to limitations of public
policy. The Shares, when issued and fully paid for in accordance with the terms
of this Agreement, will be validly issued, fully paid and non-assessable. The
issuance and sale of the Shares contemplated hereby will not give rise to any
preemptive rights or rights of first refusal on behalf of any person which have
not been waived in connection with this Offering.

 

2.4           No Conflict; Governmental Consents.

 

(a)          The execution and delivery by the Company of this Agreement and the
consummation of the transactions contemplated hereby will not result in the
violation of any material law, statute, rule, regulation, order, writ,
injunction, judgment or decree of any court or governmental authority to or by
which the Company is bound, or of any provision of the articles of amalgamation,
as amended, of the Company, and will not conflict with, or result in a material
breach or violation of, any of the terms or provisions of, or constitute (with
due notice or lapse of time or both) a default under, any lease, loan agreement,
mortgage, security agreement, trust indenture or other agreement or instrument
to which the Company is a party or by which it is bound or to which any of its
properties or assets is subject, nor result in the creation or imposition of any
lien or encumbrance upon any of the properties or assets of the Company.

 

(b)          No consent, approval, authorization or other order of any United
States or Canadian governmental authority is required to be obtained by the
Company in connection with the authorization, execution and delivery of this
Agreement or with the authorization, issue and sale of the Shares, except such
consents and filings as may be required to be made with or obtained from the
SEC, FINRA, the TSX, the OTCOB and with any state or foreign blue sky or other
Securities Regulatory Authority and any Canadian Securities Regulatory
Authority, all of which filings or consents, including the TSX Approval (as
defined herein), have been or will be timely made or obtained on or prior to
Closing (for the avoidance of doubt, other than as set forth in Section 2.9).

 

2.5           Litigation. There is no pending or, or to the knowledge of the
Company, threatened legal or governmental proceedings against the Company. The
Company is not a party or subject to the provisions of any order, writ,
injunction, judgment or decree of any court or government agency or
instrumentality. There is no action, suit, proceeding or investigation by the
Company currently pending in any court or before any arbitrator or that the
Company intends to initiate.

 

2.6           Approvals. The Company will obtain, prior to the Closing Date, the
receipt of all required third party and regulatory approvals, as applicable,
including, without limitation, the TSX Approval and no shareholder approval is
required for the Company to issue the Shares.

 

2.7           Financial Statements. The most recent annual financial statements
of the Company as filed under the Company’s issuer profile on www.sedar.com as
of the date hereof (collectively, the “Financial Statements”) accurately present
fairly the financial position and condition, the results of operations and cash
flows of the Company as at the dates and for the periods indicated thereof, have
been prepared in conformity with generally accepted accounting principles in the
United States, applied on a consistent basis throughout the periods involved,
except as otherwise stated therein, and no material changes in such positions
have taken place since the dates and for the periods indicated thereof, save in
the ordinary course of the Company’s business or as publicly announced.

 

 -8- 

 

 

2.8           Reporting Issuer in Canada; Absence of Material Changes. The
Company is a reporting issuer or the equivalent thereof in British Columbia,
Alberta, Saskatchewan, Manitoba, Ontario, Quebec, New Brunswick, Nova Scotia,
Prince Edward Island and Newfoundland, and is not in default of any requirement
under applicable securities legislation, statutes, regulations, and published
policies and rules of Canadian provincial securities and TSX regulations, and,
in particular, without limiting the generality of the foregoing, the Company is
in compliance with its obligations to make all reports and filings, including
timely disclosure of all material changes relating to it, under such applicable
securities legislation, statutes, regulations, and published policies and rules
of Canadian provincial securities laws (“Filings”), no such disclosure has been
made on a confidential basis and there is no material change relating to the
Company which has occurred and with respect to which the requisite material
change report has not been filed. The Filings complied in all material respects
with the requirements of applicable securities legislation, statutes,
regulations, and published policies and rules of Canadian provincial securities
and TSX regulations. The Filings, as of their respective dates, did not contain
any untrue statement of material fact or omit any material fact required to be
stated therein or necessary to make the statements therein, in light of the
circumstances under which they were made, not misleading. No securities
commission or regulatory authority in any of the provinces of Canada has issued
any order preventing or suspending trading of any securities of the Company.
Except as set forth in the Filings, there has not been (i) any material adverse
change or effect on the business, assets, financial condition, prospects or
results of operations of the Company (collectively, the “Business”), (ii) any
transaction that is material to the Company, (iii) any obligation, direct or
contingent, that is material to the Company, incurred by the Company or any of
its subsidiaries, (iv) any change in the outstanding indebtedness of the Company
and its subsidiaries (taken as a whole) that is material to the Company or the
Business, (v) any dividend declared, paid or made on the capital stock of the
Company, or (vi) any loss or damage (whether or not insured) to the property of
the Company or any subsidiary which has been sustained which in the case of this
clause (vi), individually or in the aggregate, could reasonably be expected to
impair in any material respect the Company’s ability to enter into and perform
on a timely basis its obligations under this Agreement.

 

2.9           Listing. The common shares of the Company are listed on the TSX.
On each Closing, the Shares issued hereunder will have been conditionally
approved for listing on the TSX (the “TSX Approval”), subject only to the
satisfaction of customary deliverables after Closing, which the Company will
perform in a timely fashion, and clearance of the PIF (as defined below) by the
TSX in respect of the Second Closing Shares.

 

2.10         No General Solicitation. Neither the Company nor, to its knowledge,
any person acting on its behalf has offered or sold or will offer or sell the
Shares by any form of general solicitation or general advertising, including,
but not limited to, the following:

 

(a)          any advertisement, article, notice or other communication published
in any newspaper, magazine, or similar media or broadcast over television or
radio; and

 

(b)          any seminar or meeting whose attendees have been invited by any
general solicitation or general advertising.

 

2.11         No Fees. No brokerage, agency, finder or other fiscal advisory or
similar fee is payable by the Company in connection with the transactions
contemplated herein.

 

2.12         Investment Company. The Company is not an “investment company”
within the meaning of such term under the Investment Company Act of 1940, as
amended, and the rules and regulations of the SEC thereunder.

 

 -9- 

 

 

2.13         Disclosure. The representations and warranties made by the Company
in this Agreement and the Filings when read together do not contain any untrue
statement of a material fact and do not omit to state a material fact necessary
to make the statements herein as a whole not misleading.

 

III.         TERMS OF SUBSCRIPTION

 

3.1           The Company will conduct the purchase and sale of the First
Closing Shares on the First Closing Date whereupon:

 

(a)          the Subscriber shall deliver to the Company, if not previously
delivered: (i) this duly completed and executed Agreement and the applicable
Accredited Investor Certificate; and (ii) the portion of the Purchase Price
payable for the First Closing Shares by wire transfer to an account designated
by the Company Counsel (collectively, the “Subscriber Deliverables”); and

 

(b)          the Company will deliver to the Subscriber at or prior to the First
Closing Date (unless otherwise specified below):

 

(i)a certificate of good standing of the Company issued by the British Columbia
Registrar of Companies dated no later than one (1) business day before the First
Closing Date;

(ii)an officer’s certificate of the Company, dated as of the First Closing Date,
as to: (I) the resolutions of the Board then in full force and effect
authorizing the execution, delivery and performance of this Agreement to be
executed by the Company and the transactions contemplated thereby; (II) the
incumbency and signatures of those of its officers authorized to act with
respect to this Agreement to be executed by such person; and (III) the full
force and validity of each organizational document of the Company and copies
thereof;

(iii)a closing certificate, dated as of the First Closing Date and duly executed
and delivered by the Chief Executive Officer or Chief Financial Officer of the
Company, certifying for and on behalf of the Company and not in their personal
capacities, to the best of the knowledge, information and belief of the persons
so signing, after having made due enquiry, that: (I) the Company has complied in
all material respects with all the covenants and satisfied all the terms and
conditions of this Agreement on its part to be complied with and satisfied at or
prior to the First Closing Date and (II) the representations and warranties of
the Company contained herein are true and correct in all respect as at the First
Closing Date;

(iv)evidence of receipt of the TSX Approval;

(v)a copy of this Agreement duly executed by the Company;

(vi)an opinion of Company Counsel in a form acceptable to the Subscriber in
respect of the First Closing Shares; and

(vii)within two (2) business days after the First Closing Date, a certificate
registered in the name of the Subscriber (or as directed by it) duly executed
and delivered by the Company, representing the First Closing Shares purchased
hereunder free and clear of all liens, security interests, claims and
encumbrances (and in this regard the Subscriber hereby authorizes and directs
the Company to deliver the certificate representing the First Closing Shares
purchased by the Subscriber pursuant to this Agreement to the address indicated
on the signature page hereto) (items (i) through (vii) collectively, the “First
Closing Company Deliverables”).

 

 -10- 

 

 

3.2           On, or as soon as practicable after, the First Closing Date, the
relevant affiliate of the Subscriber shall submit to the TSX a duly completed
and executed Personal Information Form (the “PIF”) and will take all reasonable
actions in connection with having the PIF cleared by the TSX.

 

3.3           The Company will conduct the purchase and sale of the Second
Closing Shares on the Second Closing Date whereupon:

 

(a)          the Subscriber shall deliver to the Company the portion of the
Purchase Price for the Second Closing Shares by wire transfer to an account
designated by the Company Counsel; and

 

(b)          the Company will deliver to the Subscriber at or prior to the
Second Closing Date (unless otherwise specified below):

 

(i)a certificate of good standing of the Company issued by the British Columbia
Registrar of Companies dated no later than one (1) business day before the
Second Closing Date;

(ii)an officer’s certificate of the Company, dated as of the Second Closing
Date, as to: (I) the resolutions of the Board then in full force and effect
authorizing the execution, delivery and performance of this Agreement to be
executed by the Company and the transactions contemplated thereby; (II) the
incumbency and signatures of those of its officers authorized to act with
respect to this Agreement to be executed by such person; and (III) the full
force and validity of each organizational document of the Company and copies
thereof;

(iii)a bring-down certificate, dated as of the Second Closing Date and duly
executed and delivered by the Chief Executive Officer or Chief Financial Officer
of the Company, certifying for and on behalf of the Company and not in their
personal capacities, to the best of the knowledge, information and belief of the
persons so signing, after having made due enquiry, that: (I) the Company has
complied in all material respects with all the covenants and satisfied all the
terms and conditions of this Agreement on its part to be complied with and
satisfied at or prior to the Second Closing Date and (II) the representations
and warranties of the Company contained herein are true and correct in all
respect as at the Second Closing Date, except as disclosed in an exhibit to such
certificate and none of such disclosures, alone or in the aggregate, constitute
a material adverse change to the business, assets or results of operation of the
Company;

(iv)evidence of receipt of TSX clearance of the PIF;

(v)an opinion of Company Counsel in a form acceptable to the Subscriber in
respect of the Second Closing Shares; and

(vi)within two (2) business days after the Second Closing Date, a certificate
registered in the name of the Subscriber (or as directed by it) duly executed
and delivered by the Company, representing the Second Closing Shares purchased
hereunder free and clear of all liens, security interests, claims and
encumbrances (and in this regard the Subscriber hereby authorizes and directs
the Company to deliver the certificate representing the Second Closing Shares
purchased by the Subscriber pursuant to this Agreement to the address indicated
on the signature page hereto) (items (i) through (vi) collectively, the “Second
Closing Company Deliverables”, which together with the First Closing Company
Deliverables shall constitute “Company Deliverables”, as the context requires).

 

 -11- 

 

 

IV.          CONDITIONS TO CLOSINGS

 

4.1           If, prior to the Closing, the terms and conditions contained in
this Agreement have not been complied with to the satisfaction of the
Subscriber, the Company and the Subscriber will have no further obligations
under the Agreement.

 

4.2           The Subscriber’s obligation to purchase the First Closing Shares
on the First Closing Date is subject to the fulfillment of certain conditions,
which conditions may be waived at the option of the Subscriber to the extent
permitted by law, as follows:

 

(a)          Representations and Warranties Correct. The representations and
warranties made by the Company in Article II hereof shall be true and correct in
all material respects as at the Closing Date.

 

(b)          Covenants. All covenants, agreements and conditions contained in
this Agreement to be performed by the Company on or prior to the Closing Date
shall have been performed or complied with in all material respects.

 

(c)          No Legal Order Pending. There shall not then be in effect any legal
or other order enjoining or restraining the transactions contemplated by this
Agreement.

 

(d)          No Law Prohibiting or Restricting Such Sale. There shall not be in
effect any law, rule or regulation prohibiting or restricting the sale of the
First Closing Shares (except as otherwise referred to in this Agreement) or
requiring any consent or approval of any person (including the TSX), which shall
not have been obtained, to issue the First Closing Shares (except as referred to
in this Agreement).

 

(e)          TSX Listing. The TSX shall have conditionally approved the listing
of the Shares, subject only to the satisfaction by the Company of customary
post-closing conditions imposed by the TSX in similar circumstances and
clearance of the PIF referred to in Section 3.2 and without the requirement of
the Company to obtain shareholder approval for the Offering.

 

(f)          Company Deliverables. The Company shall have delivered to the
Subscriber all First Closing Company Deliverables (other than a certificate
representing the First Closing Shares, which may be delivered after the First
Closing Date in accordance with Section 3.1(b)).

 

(g)          Opinion. The Subscriber shall have received an opinion from Company
Counsel as to customary Canadian corporate and securities matters in relation to
the First Closing Shares in a form acceptable to the Subscriber, acting
reasonably.

 

4.3           The Company’s obligation to sell the First Closing Shares on the
First Closing is subject to the fulfillment of certain conditions, which
conditions may be waived at the option of the Company to the extent permitted by
law, as follows:

 

 -12- 

 

 

(a)          Representations and Warranties Correct. The representations and
warranties made by the Subscriber in Article I hereof shall be true and correct
in all material respects.

 

(b)          Payment of Purchase Price. The Subscriber shall have delivered to
the Company the Purchase Price for the First Closing Shares purchased by it
pursuant to Section 3.1(a).

 

(c)          No Legal Order Pending. There shall not then be in effect any legal
or other order enjoining or restraining the transactions contemplated by this
Agreement.

 

(d)          No Law Prohibiting or Restricting Such Sale. There shall not be in
effect any law, rule or regulation prohibiting or restricting the sale of the
First Closing Shares or requiring any consent or approval of any person, which
shall not have been obtained, to issue the First Closing Shares (except as
otherwise provided in this Agreement).

 

(e)          TSX Listing. The TSX shall have conditionally approved the listing
of the Shares subject only to the satisfaction by the Company of customary
post-closing conditions imposed by the TSX in similar circumstances, and without
the requirement of the Company to obtain shareholder approval for the Offering.

 

(f)          Subscriber Deliverables. The Subscriber shall have delivered to the
Company all Subscriber Deliverables.

 

4.4           The Subscriber’s obligation to purchase the Second Closing Shares
on the Second Closing Date is subject to the fulfillment of certain conditions,
which conditions may be waived at the option of the Subscriber to the extent
permitted by law, as follows:

 

(a)          Cleared PIF. The TSX has confirmed that the PIF referred to in
Section 3.2 has been cleared by the TSX.

 

(b)          No Legal Order Pending. There shall not then be in effect any legal
or other order enjoining or restraining the transactions contemplated by this
Agreement.

 

(c)          No Law Prohibiting or Restricting Such Sale. There shall not be in
effect any law, rule or regulation prohibiting or restricting the sale of the
Second Closing Shares (except as otherwise referred to in this Agreement) or
requiring any consent or approval of any person (including the TSX), which shall
not have been obtained, to issue the Second Closing Shares (except as referred
to in this Agreement).

 

(d)          Company Deliverables. The Company shall have delivered to the
Subscriber all Company Deliverables (other than a certificate representing the
Second Closing Shares, which may be delivered after the Second Closing Date in
accordance with Section 3.3(b)).

 

(e)          Opinion. The Subscriber shall have received an opinion from Company
Counsel as to customary Canadian corporate and securities matters in relation to
the Second Closing Shares in substantially the same form as delivered on the
First Closing Date.

 

4.5           The Company’s obligation to sell the Second Closing Shares on the
Second Closing is subject to the fulfillment of certain conditions, which
conditions may be waived at the option of the Company to the extent permitted by
law, as follows:

 

 -13- 

 

 

(a)          Payment of Purchase Price. The Subscriber shall have delivered to
the Company the Purchase Price for the Second Closing Shares in accordance with
Section 3.3(a).

 

(b)          Cleared PIF. The TSX has confirmed that the PIF referred to in
Section 3.2 has been cleared by the TSX.

 

(c)          No Legal Order Pending. There shall not then be in effect any legal
or other order enjoining or restraining the transactions contemplated by this
Agreement.

 

(d)          No Law Prohibiting or Restricting Such Sale. There shall not be in
effect any law, rule or regulation prohibiting or restricting the sale of the
Second Closing Shares (except as otherwise referred to in this Agreement) or
requiring any consent or approval of any person (including the TSX), which shall
not have been obtained, to issue the Second Closing Shares (except as referred
to in this Agreement).

 

V.COVENANTS

 

5.1           In the event the Subscriber shall become a “control person” as
such term is defined in the Securities Act (Ontario) for reasons other than
having acquired voting rights (within such meaning of the definition of “control
person”) with respect to Common Shares other than the Shares acquired under this
Agreement, the Subscriber may, by written notice (the “Demand Notice”), require
the Company to prepare and file the necessary offering documents with one or
more Canadian securities regulatory authorities or otherwise to qualify the
Shares for distribution in one or more Canadian reporting jurisdictions (a
“Demand Registration”), and the Company will otherwise take or cause to be taken
all actions as may be necessary or desirable, in order to effect a public
offering of the Shares by the Subscriber (a “Secondary Offering”). The Demand
Notice shall state: (a) the number of Shares the Subscriber wishes to sell in
the Secondary Offering; (b) describe the nature or methods of the proposed
distribution thereof; and (c) specify the Canadian reporting jurisdictions in
which such distribution shall be made, provided that the Company is, on the date
of giving of the Demand Notice, a reporting issuer in each such Canadian
reporting jurisdiction. The Subscriber shall send the Demand Notice to the
Company.

 

5.2           The Company shall not be obliged to effect a Demand Registration
in the event the Board determines in its good faith judgment that either (i) the
effect of the filing of a prospectus would materially adversely affect the
Company including materially adversely affecting the ability of the Company to
consummate a material financing, acquisition, corporate reorganization, merger
or other material transaction involving the Company being considered at the time
of the receipt of the request for the Demand Registration; or (ii) there exists
at the time material non-public information relating to the Company the
disclosure of which the Company believes would be detrimental to the Company and
the Company has bona fide business purposes for preserving such information as
confidential (a “Valid Business Reason”), provided that in either case the
Company’s obligations under this Article Error! Reference source not found. will
be deferred for a period of not more than 90 days from the date of receipt of
the Demand Notice, provided that the Company may not defer its obligations under
this Article Error! Reference source not found. for a period of more than 120
days in any 12 consecutive months. The Company will give written notice of the
Board’s determination to postpone filing and of the fact that the Valid Business
Reason for such postponement no longer exists, in each case, promptly after the
occurrence thereof. If the Company postpones the filing of a prospectus pursuant
to this Section 5.2 and if the Subscriber that initiated the Demand
Registration, at any time prior to receiving the Company’s written notice that
the Valid Business Reason for such postponement no longer exists, advises the
Company in writing that it has determined to withdraw such request for a Demand
Registration, then such Demand Registration and the request therefor will be
deemed to be withdrawn and such request will be deemed not to have been given
for purposes of determining whether the Subscriber exercised its right to a
Demand Registration pursuant to this Article Error! Reference source not found.,
and the reasonable fees, expenses and disbursements of legal counsel to the
Subscriber incurred up to the date of withdrawal that would have been considered
distribution expenses had such Demand Registration been completed, shall be paid
by the Company.

 

 -14- 

 

 

5.3           At any time, the Subscriber shall be entitled, upon notice in
writing to the Company, to withdraw such Demand Notice; provided, however, that
the Subscriber shall pay all of the out of pocket expenses reasonably incurred
by the Company in connection with the proposed Secondary Offering.
Notwithstanding the foregoing, if and only if, the Subscriber withdraws the
Demand Notice after having learned of a material adverse change in the
condition, business or business prospects of the Company, then the Subscriber
will not be required to pay any such expenses or forfeit the right to one Demand
Registration.

 

5.4           In connection with a Secondary Offering, all distribution expenses
shall be borne by the Subscriber and the Company in proportion to the amount the
gross proceeds received by the Subscriber and the Company bear to the total
gross proceeds of the Secondary Offering, provided that the Company shall not be
responsible for the fees and disbursements of any legal counsel to the
Subscriber. If the Company is participating in the Demand Registration then the
Company shall be responsible for all fees and disbursements of legal counsel to
the Company otherwise the Subscriber shall pay the fees and disbursements of
legal counsel to the Company proportionately based on the gross proceeds
received by the Subscriber.

 

5.5           The Company shall not be obliged to effect more than three (3)
Demand Registrations in any twelve (12) month period pursuant to this Article
Error! Reference source not found.. The Subscriber shall not be permitted to
exercise its Demand Registration rights pursuant to this Article Error!
Reference source not found. prior to one hundred and eighty (180) days following
the date of this Agreement and in any event more than once in any one hundred
and eighty (180) day period.

 

5.6           Following the Second Closing Date, so long as the Subscriber owns
at least 1,315,790 Shares (subject to adjustment in the event of any share
split, consolidation, share dividend or the like), the Subscriber shall also
have unlimited registration rights relating to the inclusion of their Shares in
any prospectus filed by the Company in one or more of the Canadian reporting
jurisdictions (a “Primary Offering”). At least twenty (20) days prior to the
initial filing of a preliminary prospectus for a Primary Offering, the Company
will give written notice to the Subscriber of its intention to do so. Upon the
written request of the Subscriber given within ten (10) days after the Company
provides such notice (which request will state the number of Shares that is
proposed to be included in such preliminary prospectus by the Subscriber (the
“Piggy Back Shares”), the Company will cause all such Piggy Back Shares to be
qualified for sale under the preliminary prospectus for a Primary Offering (a
“Piggy Back Registration”); provided that the Company will have the right to
postpone or withdraw any Piggy Back Registration initiated by the Company prior
to a receipt being issued for a preliminary prospectus pursuant to this Section
5.6 without obligation to the Subscriber. If the Company withdraws any
registration initiated by it, for whatever reason, the Subscriber may initiate a
Demand Registration, subject to, and in accordance with, the provisions of
Article Error! Reference source not found. hereof.

 

5.7           The Company will pay all distribution expenses in connection with
each Piggy Back Registration and the Subscriber will pay all selling expenses of
the Subscriber, in proportion to the gross proceeds received by the Subscriber
from any Piggy Back Registration.

 

 -15- 

 

 

5.8           Following the Second Closing Date, so long as the Subscriber owns
at least 1,315,790 Shares (subject to adjustment in the event of any share
split, consolidation, share dividend on the like), in the event the Company
wishes to complete a private or public bona fide equity financing (an “Equity
Financing”), the Company shall provide the Subscriber with reasonable notice of
and the opportunity to participate in such Equity Financing so as to maintain
its then pro rata voting interest in the Company; provided, however, that in no
event shall this Section 5.8: (i) permit the Subscriber to acquire securities
which represent, together with the securities owned or controlled by the
Subscriber immediately prior to the Equity Financing, more than 19.9% of the
outstanding voting securities of the Company upon completion of the Equity
Financing; or (ii) permit the Subscriber to acquire securities to the extent
that the TSX would require the Company to seek and obtain security holder
approval as contemplated by Section 604 of the TSX Company Manual for the Equity
Financing (and, absent such level of Subscriber participation, security holder
approval would not be required).

 

VI.          Trading in COMPANY Securities

 

6.1           The Subscriber covenants and agrees that it will not purchase,
sell, short, or engage in any securities transactions relating to the Shares
whatsoever (or advise any others to do so) while in possession of material
non-public information regarding the Company, including that it is contemplating
the Offering.

 

VII.         SURVIVAL

 

7.1           The representations and warranties contained in this Agreement and
in each applicable Accredited Investor Certificate attached hereto shall survive
for a period of two (2) years after the Second Closing Date (and if none, the
First Closing Date) and continue in full force and effect and be binding upon
the Company and the Subscriber, notwithstanding the completion of the purchase
of the Shares by the Subscriber pursuant hereto, or the subsequent disposition
of the Shares by the Subscriber. For greater certainty, all covenants under this
Agreement shall survive the execution and delivery of this Agreement and the
Closing indefinitely.

 

VIII.         MISCELLANEOUS

 

8.1           Any notice or other communication given hereunder shall be deemed
sufficient if in writing and sent by registered or certified mail, return
receipt requested, or delivered by hand against written receipt therefor,
addressed as follows:

 

if to the Company, to it at:

 

Fennec Pharmaceuticals Inc.
PO Box 13628

68 TW Alexander Drive

Research Triangle Park, NC 27709

Attention: Rosty Raykov, President and Chief Executive Officer

 

if to the Subscriber, to the Subscriber’s address indicated on the signature
page of this Agreement.

 

Notices shall be deemed to have been given or delivered on the date of mailing,
except notices of change of address, which shall be deemed to have been given or
delivered when received.

 

8.2           Except as otherwise provided herein, this Agreement shall not be
changed, modified or amended except in writing signed by the parties to be
charged, and this Agreement may not be discharged except by performance in
accordance with its terms or in writing signed by the party to be charged.

 

 -16- 

 

 

8.3           This Agreement shall be binding upon and inure to the benefit of
the parties hereto and to their respective heirs, legal representatives,
successors and assigns. This Agreement, together with the schedules hereto, sets
forth the entire agreement and understanding between the parties as to the
subject matter hereof and merges and supersedes all prior discussions,
agreements and understandings of any and every nature among them.

 

8.4           Upon the execution and delivery of this Agreement by the
Subscriber, this Agreement shall become a binding obligation of the Subscriber
with respect to the purchase of Shares as herein provided.

 

8.5           All questions concerning the construction, validity, enforcement
and interpretation of this Agreement shall be governed by and construed and
enforced in accordance with the internal laws of the Province of British
Columbia, without regard to the principles of conflicts of law thereof. Each
party hereby irrevocably waives personal service of process and consents to
process being served in any such suit, action or proceeding by mailing a copy
thereof via registered or certified mail or overnight delivery (with evidence of
delivery) to such party at the address in effect for notices to it under this
Agreement and agrees that such service shall constitute good and sufficient
service of process and notice thereof. Nothing contained herein shall be deemed
to limit in any way any right to serve process in any other manner permitted by
law. The parties hereby waive all rights to a trial by jury. If either party
shall commence an action or proceeding to enforce any provisions of this
Agreement, then the prevailing party in such action or proceeding shall be
reimbursed by the other party for its reasonable attorneys’ fees and other costs
and expenses incurred with the investigation, preparation and prosecution of
such action or proceeding.

 

8.6           The holding of any provision of this Agreement to be invalid or
unenforceable by a court of competent jurisdiction shall not affect any other
provision of this Agreement, which shall remain in full force and effect. If any
provision of this Agreement shall be declared by a court of competent
jurisdiction to be invalid, illegal or incapable of being enforced in whole or
in part, such provision shall be interpreted so as to remain enforceable to the
maximum extent permissible consistent with applicable law and the remaining
conditions and provisions or portions thereof shall nevertheless remain in full
force and effect and enforceable to the extent they are valid, legal and
enforceable, and no provisions shall be deemed dependent upon any other covenant
or provision unless so expressed herein.

 

8.7           It is agreed that a waiver by either party of a breach of any
provision of this Agreement shall not operate, or be construed, as a waiver of
any subsequent or other breach by that same party.

8.8           The parties agree to execute and deliver all such further
documents, agreements and instruments and take such other and further action as
may be necessary or appropriate to carry out the purposes and intent of this
Agreement.

 

8.9           This Agreement may be executed in two or more counterparts,
including via facsimile or PDF, each of which shall be deemed an original, but
all of which shall together constitute one and the same instrument.

 

8.10         Nothing in this Agreement shall create or be deemed to create any
rights in any person or entity not a party to this Agreement. The Subscriber
hereby acknowledges and agrees that it shall bear all costs and expenses
incurred by it (including any fees and disbursements of any special counsel
retained by it) relating to the sale of the Shares to the Subscriber.

 

 -17- 

 

 

IX.          CONFIDENTIAL INVESTOR QUESTIONNAIRE

 

9.1           The Subscriber represents that it is an “accredited investor”
within the meaning of Rule 501(a) of Regulation D under the Act because it comes
within any of the following categories at each time of the sale of the Shares to
the Subscriber (please initial beside the categories below applicable to the
Subscriber). The undersigned agrees to furnish any additional information which
the Company deems necessary in order to verify the answers set forth below:

 

_____ any bank as defined in Section 3(a)(2) of the Securities Act, or any
savings and loan association or other institution as defined in Section
3(a)(5)(A) of such Act whether acting in its individual or fiduciary capacity,
any broker or dealer registered pursuant to Section 15 of the United States
Securities Exchange Act of 1934, as amended, any insurance company as defined in
Section 2(a)(13) of the Securities Act, any investment company registered under
the U.S. Investment Company Act of 1940 or a business development company as
defined in Section 2(a)(48) of the U.S. Investment Company Act of 1940, any
small business investment company licensed by the U.S. Small Business
Administration under Section 301(c) or (d) of the U.S. Small Business Investment
Act of 1958, any plan established and maintained by a state, its political
subdivisions, or any agency or instrumentality of a state or its political
subdivisions for the benefit of its employees, if such plan has total assets in
excess of $5,000,000, any employee benefit plan within the meaning of the U.S.
Employee Retirement Income Security Act of 1974, if the investment decision is
made by a plan fiduciary, as defined in Section 3(21) of the U.S. Employee
Retirement Income Security Act of 1974, which is either a bank, savings and loan
association, insurance company, or registered investment adviser, or if the
employee benefit plan has total assets in excess of $5,000,000 or, if a
self-directed plan, with investment decisions made solely by persons that are
accredited investors;

 

_____ any private business development company as defined in Section 202(a)(22)
of the U.S. Investment Advisers Act of 1940;

 

_____ any organization described in Section 501(c)(3) of the U.S. Internal
Revenue Code, corporation, Massachusetts or similar business trust, or
partnership, not formed for the specific purpose of acquiring the securities
offered, with total assets in excess of $5,000,000;

 

_____ any director, executive officer, or general partner of the issuer of the
securities being offered or sold, or any director, executive officer, or general
partner of a general partner of that issuer;

 

_____ any natural person whose individual net worth, or joint net worth with
that person's spouse, at the time of his purchase exceeds $1,000,000 (excluding
such person’s primary residence) ;

 

_____ any natural person who had an individual income in excess of $200,000 in
each of the two most recent years or joint income with that person's spouse in
excess of $300,000 in each of those years and has a reasonable expectation of
reaching the same income level in the current year;

 

_____ any trust, with total assets in excess of $5,000,000, not formed for the
specific purpose of acquiring the securities offered, whose purchase is directed
by a sophisticated person as described in Rule 506(b)(2)(ii) of Regulation D
under the Securities Act; or

 

_____ any entity in which all of the equity owners are accredited investors.

 

The undersigned agrees that the undersigned will notify the Company at any time
on or prior to either Closing, in the event that the representations and
warranties in this Agreement shall cease to be true, accurate and complete.

 

9.2           SUITABILITY (please answer each question)

 

 -18- 

 

 

(a)For an individual Subscriber, please describe your current employment,
including the company by which you are employed and its principal business:

 

 

  

 

 

 

 

 

 

(b)For an individual Subscriber, please describe any college or graduate degrees
held by you:

 

 

 

 

 

 

 

 

 

(c) For all Subscribers, please list types of prior investments:

 

 

 

 

 

 

 

 

 

(d)For all Subscribers, please state whether you have you participated in other
private placements before:

 

YES     NO  

 

(e)If your answer to question (d) above was “YES”, please indicate frequency of
such prior participation in private placements of:

 

    Public
Companies   Private
Companies   Public or Private
Biotechnology Companies Frequently             Occasionally             Never  
         

 

(f)For individual Subscribers, do you expect your current level of income to
significantly decrease in the foreseeable future:

 

YES     NO  

 

(g)For trust, corporate, partnership and other institutional Subscribers, do you
expect your total assets to significantly decrease in the foreseeable future:

 

YES     NO  

 

 -19- 

 

 

(h)For all Subscribers, do you have any other investments or contingent
liabilities which you reasonably anticipate could cause you to need sudden cash
requirements in excess of cash readily available to you:

 

YES     NO  

 

(i)For all Subscribers, are you familiar with the risk aspects and the
non-liquidity of investments such as the securities for which you seek to
purchase?

 

YES     NO  

 

(j)For all Subscribers, do you understand that there is no guarantee of
financial return on this investment and that you run the risk of losing your
entire investment?

 

YES     NO  

 

9.3           MANNER IN WHICH TITLE IS TO BE HELD. (circle one)

 

(a)           Individual Ownership

(b)           Community Property

(c)           Joint Tenant with Right of Survivorship (both parties must sign)

(d)           Partnership*

(e)           Tenants in Common

(f)            Company*

(g)           Trust*

(h)           Other

 

*If Shares are being purchased for by an entity, a Certificate of Signatory must
also be completed.

 

9.4            FINRA AFFILIATION.

 

Are you affiliated or associated with an FINRA member firm (please check one):

 

YES     NO  

 

If Yes, please describe:

_________________________________________________________

_________________________________________________________

_________________________________________________________

 

*If Subscriber is a Registered Representative with an FINRA member firm, have
the following acknowledgment signed by the appropriate party:

 

 -20- 

 

 

The undersigned FINRA member firm acknowledges receipt of the notice required by
the Rules of Conduct.

 

    Name of FINRA Member Firm       By:       Authorized Officer         Date:  
 

 

9.5           The undersigned is informed of the significance to the Company of
the foregoing representations and answers contained in the Confidential Investor
Questionnaire contained in this Article IX and such answers have been provided
under the assumption that the Company will rely on them.

 

[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK]

 

 -21- 

 

 

Name of Subscriber: _________________________________________________

 

    Signature           Name Typed or Printed           Address          
Country, City, State and Zip Code           Telephone           Facsimile      
    Tax ID # or Social Security #  

 

Name in which Shares should be issued:  ______________________________

 

Dated: __________________ _____, 2016

 

   

 

 

This Agreement is agreed to and accepted as of __________________ _____, 2016.

 

    FENNEC PHARMACEUTICALS Inc.           By:       Name:       Title:

 

 -23- 

 

 

SCHEDULE “A”

SUMMARY OF OFFERING TERMS

 

Confidential

 

This confidential term sheet summarizes the principal terms of a proposed equity
financing by Fennec Pharmaceuticals Inc. Except as described below next to the
heading, Confidentiality/No Trading (which is intended to binding on proposed
investors), this term sheet is for discussion purposes only; there is no
obligation on the part of any negotiating party until definitive transaction
documents are signed.

 

New Issue

[tpg24.jpg]

 

TERM SHEET

Private Placement of COMMON Shares

 

Issuer: Fennec Pharmaceuticals Inc. (the “Company”).     Offering: Private
placement of up to 2,631,579 common shares in the capital of the Company (the
“Shares”)     Offering Size: USD$5,000,000.10     Issue Price: USD$1.90 per
Share     Use of Proceeds: The Company intends to use the net proceeds of the
Offering for STS development and general corporate purposes.     Hold Period: No
prospectus or offering memorandum will be prepared. The Shares will be subject
to certain hold periods in the United States pursuant to US securities laws and
a hold period of four months and a day following the Closing Date pursuant to
Canadian securities laws.     Listing: The Company’s common shares are listed on
the TSX (FRX) and, in the United States, are quoted on OTC (FENCF).  The Company
will obtain the necessary approvals to list the Shares issued under this
Offering on the TSX.     Closing Date: As soon as practicable following
regulatory approval (the “Closing Date”).     Confidentiality/No Trading:
Investor understands and agrees that this Term Sheet, and the information set
forth herein, constitutes confidential information and, accordingly, each
investor agrees not to purchase, sell, short or engage in any securities
transactions relating to the Company’s securities whatsoever (or advise others
to do so) in violation of applicable securities laws.

 

 -24- 

 

 

SCHEDULE “B”

REGULATION “S” RESALE REPRESENTATION LETTER

 

Fennec Pharmaceuticals Inc.
PO Box 13628

68 TW Alexander Drive

Research Triangle Park, NC 27709

Attention: President and Chief Executive Officer

 

To Whom It May Concern:

 

The undersigned (A) acknowledges that the sale of the securities of Fennec
Pharmaceuticals Inc. (the “Company”) to which this declaration relates is being
made in reliance on Rule 904 of Regulation S under the United States Securities
Act of 1933, as amended (the “Act”) and (B) certifies that: (1) the offer of
such securities was not made to a person in the United States and either (a) at
the time the buy order was originated, the buyer was outside the United States,
or the seller and any person acting on its behalf reasonably believes that the
buyer was outside the United States or (b) the transaction was executed on or
through the facilities of the Toronto Stock Exchange and neither the seller nor
any person acting on its behalf knows that the transaction has been prearranged
with a buyer in the United States; (2) neither the seller (or its affiliates)
nor any person acting on its behalf engaged in any “directed selling efforts” in
the United States in connection with the offer and sale of such securities; (3)
the sale is bona fide and not for the purpose of “washing off” the resale
restrictions imposed because the securities are “restricted securities” (as such
term is defined in Rule 144(a)(3) under the Act); (4) the seller does not have a
short position in the securities sold and does not intend to replace the
securities sold in reliance on Rule 904 with fungible unrestricted securities;
(5) the contemplated sale is not a transaction, or part of a series of
transactions which, although in technical compliance with Regulation S, is part
of a plan or scheme to evade the registration provisions of the Act; and (6) the
undersigned is not an “affiliate” (as defined in Rule 405 under the Act) of the
Company. Terms used herein have the meanings given to them by Regulation S.

 

    Name:   Title:   Date:  

 

 -25- 

 

 

CERTIFICATE OF SUBSEQUENT SALE

 

[Name and Address of Transfer Agent]

 

RE:Sale of Shares of Common Stock of Fennec Pharmaceuticals Inc. (the “Company”)

 

Dear Sir/Madam:

 

The undersigned hereby certifies, in connection with the sale of Common Shares
of the Company, that the undersigned has sold the shares in compliance with all
securities laws applicable to the undersigned.

 

Selling Stockholder (the beneficial owner):   

 

Record Holder (e.g., if held in name of nominee):   

 

Restricted Stock Certificate No.(s):   

 

Number of Shares Sold:   

 

Date of Sale:   

 

  Very truly yours,     Dated: ________________________ By:           Print
Name:            Title:  

 

cc:Fennec Pharmaceuticals Inc.
PO Box 13628

68 TW Alexander Drive

Research Triangle Park, NC 27709

Attention: President and Chief Executive Officer

 

 -26- 

 

 

SCHEDULE “C”

 

ACCREDITED INVESTOR CERTIFICATE CANADA – NATIONAL INSTRUMENT 45-106

 

TO:FENNEC PHARMACEUTICALS INC.

 

In connection with the subscription for Shares of Fennec Pharmaceuticals Inc.
(the “Company”), the undersigned (the “Subscriber”) hereby represents and
warrants that the Subscriber is an “accredited investor” as defined in National
Instrument 45-106 – Prospectus Exemptions by virtue of being (check one):

 

¨   (a)  

(i) except in Ontario, a Canadian financial institution or a bank listed in
Schedule III to the Bank Act (Canada),

(ii) in Ontario, a bank listed in Schedule I, II or III to the Bank Act
(Canada).

(iii) in Ontario, an association to which the Cooperative Credit Associations
Act (Canada) applies or a central cooperative credit society for which an order
has been made under subsection 473(1) of that Act.

(iv) in Ontario, a loan corporation, trust company, trust corporation, insurance
company, treasury branch, credit union, caisse populaire, financial services
cooperative or credit union league or federation that is authorized by a statute
of Canada or Ontario to carry on business in Canada or Ontario, as the case may
be.

¨   (b)   the Business Development Bank of Canada, ¨   (c)   a subsidiary of any
person or company referred to in clause (a) or (b), if the person or company
owns all of the voting securities of the subsidiary, except the voting
securities required by law to be owned by directors of that subsidiary, ¨   (d)
  a person or company registered under the securities legislation of a province
or territory of Canada as an adviser or dealer, except as otherwise prescribed
by regulation, ¨   (e)   an individual registered under the securities
legislation of a jurisdiction of Canada as a representative of a person referred
to in paragraph (d), ¨   (f)   an individual formerly registered under the
securities legislation of a jurisdiction of Canada, other than an individual
formerly registered solely as a representative of a limited market dealer under
one or both of the Securities Act (Ontario) or the Securities Act (Newfoundland
and Labrador), ¨   (g)   the Government of Canada, the government of a province
or territory of Canada, or any Crown corporation, agency or wholly owned entity
of the Government of Canada or of the government of a province or territory of
Canada, ¨   (h)   a municipality, public board or commission in Canada and a
metropolitan community, school board, the Comité de gestion de la taxe scolaire
de l’Île de Montréal or an intermunicipal management board in Québec, ¨   (i)  
any national, federal, state, provincial, territorial or municipal government of
or in any foreign jurisdiction, or any agency of that government, ¨   (j)   a
pension fund that is regulated by either the Office of the Superintendent of
Financial Institutions (Canada) or a pension commission or similar regulatory
authority of a province or territory of Canada,

 

 -27- 

 

 

¨   (k)   an individual who, either alone or with a spouse, beneficially owns
financial assets having an aggregate realizable value that, before taxes but net
of any related liabilities, exceeds $1,000,000, and the undersigned has
completed and signed the enclosed Form 45-106F9, ¨   (l)   an individual who
beneficially owns financial assets having an aggregate realizable value that,
before taxes but net of any related liabilities, exceeds $5,000,000, ¨   (m)  
an individual whose net income before taxes exceeded $200,000 in each of the 2
most recent calendar years or whose net income before taxes combined with that
of a spouse exceeded $300,000 in each of the 2 most recent calendar years and
who, in either case, reasonably expects to exceed that net income level in the
current calendar year, and the undersigned has completed and signed the enclosed
Form 45-106F9, ¨   (n)   an individual who, either alone or with a spouse, has
net assets of at least $5,000,000, and the undersigned has completed and signed
the enclosed Form 45-106F9, ¨   (o)   a person, other than an individual or
investment fund, that has net assets of at least $5,000,000 as shown on its most
recently prepared financial statements, and that has not been created or used
solely to purchase or hold securities as an accredited investor, ¨   (p)  

an investment fund that distributes or has distributed its securities only to:

(i)           a person that is or was an accredited investor at the time of the
distribution,

(ii)          a person that acquires or acquired securities in the circumstances
referred to in sections 2.10 of National Instrument 45-106 (“NI 45-106”)
[Minimum amount investment], or 2.19 of NI 45-106 [Additional investment in
investment funds], or

(iii)         a person described in paragraph (i) or (ii) that acquires or
acquired securities under section 2.18 of NI 45-106 [Investment fund
reinvestment],

¨   (q)   an investment fund that distributes or has distributed securities
under a prospectus in a jurisdiction of Canada for which the regulator or, in
Québec, the securities regulatory authority, has issued a receipt, ¨   (r)   a
trust company or trust corporation registered or authorized to carry on business
under the Trust and Loan Companies Act (Canada) or under comparable legislation
in a jurisdiction of Canada or a foreign jurisdiction, acting on behalf of a
fully managed account managed by the trust company or trust corporation, as the
case may be, ¨   (s)   a person acting on behalf of a fully managed account
managed by that person, if that person is registered or authorized to carry on
business as an adviser or the equivalent under the securities legislation of a
jurisdiction of Canada or a foreign jurisdiction, ¨   (t)   a registered charity
under the Income Tax Act (Canada) that, in regard to the trade, has obtained
advice from an eligibility adviser or an adviser registered under the securities
legislation of the jurisdiction of the registered charity to give advice on the
securities being traded, ¨   (u)   an entity organized in a foreign jurisdiction
that is analogous to the entity referred to in paragraph (a)-(d) or (j) in form
and function,

 

 -28- 

 

 

¨   (v)   a person in respect of which all of the owners of interests, direct,
indirect or beneficial, except the voting securities required by law to be owned
by directors, are persons that are accredited investors, ¨   (w)   an investment
fund that is advised by a person registered as an adviser or a person that is
exempt from registration as an adviser, ¨   (x)   a person that is recognized or
designated by the securities regulatory authority or, except in Ontario and
Québec, the regulator as an accredited investor, or ¨   (y)   a trust
established by an accredited investor for the benefit of the accredited
investor’s family members of which a majority of the trustees are accredited
investors and all of the beneficiaries are the accredited investor’s spouse, a
former spouse of the accredited investor or a parent, grandparent, brother,
sister, child or grandchild of that accredited investor, of that accredited
investor’s spouse or of that accredited investor’s former spouse.

 

Dated this ____ day of _____________, 2016

 

  Signed:            Name:           For:           Title:  

 

 -29- 

 

 

SCHEDULE “D”

 

ACCREDITED INVESTOR CERTIFICATE FOR RESIDENTS OF

AN INTERNATIONAL JURISDICTION

 

TO: FENNEC PHARMACEUTICALS INC.

 

Any capitalized terms not defined herein shall have the meaning set forth in the
Subscription Agreement between the undersigned and Fennec Pharmaceuticals Inc.
dated on or about the date hereof.

 

In connection with the subscription for Shares of Fennec Pharmaceuticals Inc.
(the “Company”), the undersigned (the “Subscriber”) hereby represents, warrants
and covenants (on its own behalf or, if applicable, on behalf of those for whom
the Subscriber is contracting hereunder) and certifies to the Company and
acknowledges that the Company is relying thereon that:

 

General

 

A.The Subscriber is resident in an International Jurisdiction (as defined in the
Subscription Agreement) or is subject to the laws of that International
Jurisdiction;

 

B.The Subscriber complies with the requirements of all applicable securities
laws in their International Jurisdiction and will provide such evidence of
compliance with all such matters as the Company may request;

 

C.Upon execution of this Accredited Investor Certificate by the Subscriber, this
Certificate shall be incorporated into and form a part of the Subscription
Agreement;

 

D.The Subscriber is purchasing the Shares as principal for its own account and
not for the benefit of any other person, for investment only, and will comply
with all applicable securities laws and with the policies of the TSX concerning
the purchase, the holding of and the resale restrictions on the securities; or
is acting as agent for one or more disclosed purchasers, each disclosed
purchaser is purchasing as principal for its own account and not for the benefit
of any other person, for investment only, and not with a view to the resale or
distribution of all or any of the Shares;

 

Prospectus Exemptions

 

E.The Subscriber is knowledgeable of securities legislation having application
or jurisdiction over the Subscriber and the Offering (other than the laws of
Canada and the U.S.) which would apply to this subscription;

 

F.The Subscriber is purchasing the Shares pursuant to exemptions from any
prospectus, registration or similar requirements under the laws of that
International Jurisdiction or, if such is not applicable, the Subscriber is
permitted to purchase the Shares, and the Company does not have any filing
obligations in the International Jurisdiction; and

 

G.No laws in the International Jurisdiction require the Company to make any
filings or seek any approvals of any kind whatsoever from any regulatory
authority of any kind whatsoever in the International Jurisdiction.

 

 -30- 

 

 

Dated this ____ day of _____________, 2016

 

  Signed:            Name:           For:           Title:  

 

 -31-