Exhibit 10.19

CONSULTING AGREEMENT

This Consulting Agreement, effective as of May 11, 2007, is between Curis, Inc.,
having a place of business at 45 Moulton Street, Cambridge, MA 02138 (“Curis”),
and Dr. Stephen K. Carter, having an address at 263 West End Avenue, New York
City, New York 10023 (“Consultant”).

WHEREAS, Curis desires to have the benefit of Consultant’s knowledge and
experience, and Consultant desires to provide consulting services to Curis as
provided in this Agreement;

NOW, THEREFORE, in consideration of the promises set forth in the Agreement,
Curis and Consultant hereby agree as follows:

 

1. Term. The term of this Agreement shall be for a period of one year from the
effective date or until earlier terminated by either party. Either party may
terminate the Agreement by providing thirty (30) days prior written notice to
the other party.

 

2. Consulting duties.

 

  (a) During the term, Consultant shall provide Curis or to Curis’ designee, in
accordance with the specifications outlined in the attached Project Exhibit A,
and any other Project Exhibits which may be attached hereto from time to time,
as agreed to in writing by both parties, such consulting services at such times
and places as Curis may from time to time request. Curis shall give Consultant
reasonable advance notice of any service required.

 

  (b) All work to be performed by Consultant for Curis shall be under the
general supervision of Curis’ Chief Executive Officer or his designee.

 

  (c) Consultant shall devote his best efforts and ability to the performance of
the duties attaching to this obligation, devoting an amount of time as mutually
agreed. All work performed by Consultant for Curis shall be at times reasonably
convenient to him/her. Consultant agrees to furnish Curis with written reports
with respect to such consulting services if and when requested by Curis.

 

3. Compensation. In consideration for the services rendered by Consultant to
Curis during the Term, Curis shall pay Consultant compensation in the amount of
Two Thousand dollars ($2000.00) per day for each day of consulting work, or Two
Hundred and Fifty dollars ($250.00) per hour for portions thereof of consulting
work performed on behalf of Curis, not to exceed $20,000 dollars for the term of
this Agreement unless as otherwise agreed to by Curis. Payment of such amounts
will be made upon Curis’ approval of a detailed invoice from Consultant. Curis
shall reimburse Consultant for reasonable out-of-pocket expenses incurred in the
performance of his duties hereunder as requested by Curis upon presentation of
reasonably detailed receipts.

 

4. Status. Consultant’s relation to Curis shall be that of an independent
contractor and neither this Agreement nor the services to be rendered hereunder
shall for any purpose whatsoever or in any way or manner create any
employer-employee relationship between the parties. Consultant shall not be
deemed an agent for any purpose and shall have no authority to bind Curis.

 

5. Inventions, Proprietary Rights and Disclosures.

 

  (a)

Consultant agrees to disclose promptly to Curis all inventions, discoveries,
designs, improvements and all other intellectual property rights (collectively
referred to as “Inventions”) made or perfected in the performance of, or arising
out of, the work to be performed by Consultant for Curis, and will maintain
adequate and current written records (in the form of notes, sketches, drawings
and as may be specified by Curis), properly corroborated, to document the
conception and/or first actual reduction to practice of any Invention. Such
written records shall be available to and remain the sole property of Curis at
all times. All such Inventions and patents therefor shall be the exclusive
property of Curis. Consultant

 

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hereby undertakes and agrees to execute such assignments and other papers which,
in the opinion of Curis, are necessary at any time to permit the filing and
prosecution of copyrights, applications for copyrights, applications for patents
covering the Inventions or are otherwise required for compliance with the
provisions of this paragraph.

 

  (b) Consultant agrees that the services furnished pursuant to the work to be
performed hereunder, the data and Inventions generated by the said work and any
and all information, data, specifications, techniques, formulae and processes
disclosed by Curis in connection therewith (collectively referred to as
“Confidential Information”) are the property of Curis and are confidential and
proprietary to Curis. Consultant agrees that he/she shall not use Confidential
Information for any purpose other than as advised or directed by Curis
regardless of whether such Confidential Information has been furnished or made
available to Consultant by Curis or is original with Consultant. Without Curis’
express written consent first obtained, Consultant agrees that he/she shall not
disclose or make available any Confidential Information to any third party
regardless of whether such Confidential Information has been furnished or made
available to Consultant by Curis or is original with Consultant. Consultant
shall not discuss the nature of his activities in connection with Curis with
anyone except authorized representatives of Curis. At Curis’ request, Consultant
shall provide Curis with all Confidential Information furnished to Consultant by
Curis or original with Consultant in connection with his services furnished
hereunder which has been reduced to writing and retain no copies thereof.
Consultant understands that in receiving Confidential Information, he/she
receives no right to a license, implied or otherwise, under any patent or other
rights now or hereafter owned or controlled by Curis.

 

  (c) The foregoing obligations of confidentiality and non-use shall not apply
to:

 

  (1) information which at the time of disclosure by Curis hereunder to
Consultant or at the time of generation by Consultant is in the public domain;

 

  (2) information which after disclosure by Curis to Consultant or generation by
Consultant is published or otherwise becomes part of the public domain through
no fault of Consultant, but only after it is so published or so becomes part of
the public domain;

 

  (3) information received by Consultant from a third party who is legally in
possession of the same and not under an obligation of confidentiality with
respect thereto; or

 

  (4) information which was already in Consultant’s possession at the time of
receipt from Curis, as evidenced by written records;

however, Confidential Information shall not be deemed within the foregoing
exceptions if

 

  (i) specific information is merely embraced by more general information in the
public domain or Consultant’s possession, or

 

  (ii) it constitutes a combination which can be reconstructed from multiple
sources in the public domain or Consultant’s possession, none of which shows the
whole combination of the Confidential Information.

 

  (d) Consultant warrants and represents that no trade secrets or other
confidential information of any other person, firm, corporation, institution or
other entity will be wrongfully disclosed by him/her to Curis in connection with
any of the services called for hereunder. Consultant further warrants and
represents that none of the provisions of this Agreement, nor the services which
will be performed by Consultant pursuant to the work to be performed hereunder,
contravenes or is in conflict with any agreement of Consultant with, or
obligation to, any other person, firm, corporation, institution or other entity
including, without limiting the generality of the foregoing, employment
agreements, consulting agreements, disclosure agreements or agreements for
assignment of inventions. Consultant agrees that his services to other
enterprises may result in a conflict of interest with his obligations to Curis
under this Agreement, and agrees to inform Curis of his services to other
enterprises and, in the case of conflict of interest, to immediately inform
Curis and resolve the conflict in a mutually satisfactory manner.

 

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6. Survival of Provisions. The provisions of paragraph 5 hereof shall survive
the termination or expiration of this Agreement.

 

7. Assignability and Binding Effect. Neither this Agreement nor any interest
shall be assignable by either party unless such assignment is mutually agreed to
in writing by the parties hereto; provided, however, that Curis may assign this
Agreement to any corporation with which Curis may merge or consolidate or to
which Curis may assign substantially all of its assets or that portion of its
business to which this Agreement pertains without obtaining the agreement of
Consultant.

 

8. Headings. The paragraph headings contained herein are included solely for
convenience of reference and shall not control or affect the meaning or
interpretation of any of the provisions of this Agreement.

 

9. Notices. Any notices or other communications hereunder by either party shall
be in writing and shall be deemed to have been duly given if delivered
personally to the other party or sent by registered or certified mail, return
receipt requested, to the other party at the following addresses:

 

If to Curis:   

Curis, Inc.

45 Moulton Street

Cambridge, MA 02138

Attention: Legal Department

         If to Consultant:   

Dr. Stephen K. Carter

           

 

     or at such other address as such other party may designate in conformity
with the foregoing.

 

10. Entire Agreement; Modification. This document sets forth the entire
Agreement between the parties hereto with respect to the subject matter hereof.
This Agreement shall not be changed or modified in any manner except by an
instrument signed by the duly authorized officers of each of the parties hereto,
which document shall make specific reference to this Agreement and shall express
the plan or intention to modify same.

 

11. Counterparts. This Agreement may be executed in any number of counterparts,
each of which shall be deemed an original, but all of which together shall
constitute one and the same instrument.

IN WITNESS WHEREOF, this Agreement is executed under seal by both parties and
deemed to be governed by the laws of the Commonwealth of Massachusetts,
exclusive of its conflicts of law principles.

 

CURIS, INC.     CONSULTANT: By:  

/s/ MICHAEL P. GRAY        

    By:  

/s/ STEPHEN K. CARTER

Name:   Michael P. Gray     Name:   Stephen K. Carter Title:   COO and CFO    
SS#:   [Insert #]

 

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Exhibit A

During the term of this agreement, Dr. Carter shall provide to Curis or to Curis
designee consulting services for Curis’ Targeted Cancer Drug Development
programs, including pre-clinical development, clinical development, and
strategic planning for advancing Curis’ drug candidates into and through the
clinic. Consulting services will be provided at such times and places as Curis
may from time to time request. These services may include, but are not limited
to the development of IND packages, clinical documents, protocols and timelines,
and intellectual property summaries for potential in-licensing opportunities
Curis is considering. Curis shall give Dr. Carter reasonable advance notice of
any service required. Dr. Carter agrees to furnish Curis with written reports
with respect to such consulting services if and when requested by Curis.

 

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