Exhibit 10.6

Confidential Materials omitted and filed separately with the
Securities and Exchange Commission. Asterisks denote omissions.
Amendment 2
OEM DEVELOPMENT AND PURCHASE AGREEMENT
This Amendment 2 to the OEM Development and Purchase Agreement dated the 24th
day of July, 2003, as amended by Addendum 1 (with a date of June 5, 2006 in the
footer of such document) (the “Agreement”), by and between Aspect Medical
Systems, Inc. (“Aspect”) and Mindray DS USA, Inc. (“Datascope”) (formerly
Datascope Corp.) is made as of this 3rd day of October, 2009 (the “Amendment
Effective Date”).
Terms used, but not defined, in this Amendment 2, have the meaning ascribed to
them in the Agreement.

  1.   Section 2 of the Agreement shall be replaced by the following:

  2   Definitions     2.1   “Affiliate” shall mean, with respect to either
Aspect or Datascope, any other business entity which, directly or indirectly,
controls, is controlled by, or is under common control with Aspect or Datascope,
respectively. The parties agree and acknowledge that Mindray and its affiliates
are Affiliates of Datascope.     2.2   “Aspect BIS Sensor” means a single use
disposable sensor manufactured by Aspect for use with the Aspect BISx Kit in the
OR, ICU, and other sedation locations that is required to generate Aspect’s
Bispectral Index. These sensors include the BIS Quatro Sensor, the BIS Bilateral
Sensor and the BIS Pediatric Sensor.     2.3   “Aspect’s Bispectral Index” or
“BIS” is Aspect’s proprietary processed EEG parameter that may be used as an aid
in monitoring the effects of certain anesthetic agents.     2.4   “Aspect BISx
Kit” is the Aspect components of the Datascope BISx System that are developed
and manufactured by or for Aspect and licensed/sold to Datascope under this
Agreement including the BISx or BISx4, and the Patient Interface Cable (“PIC”).
    2.5   “Aspect Products” means Aspect BISx Kit and any other product that can
be ordered by Datascope as listed in Exhibit A (Aspect Products and Purchase
Prices).     2.6   “BISx” is an Aspect device that acquires up to two channels
of EEG and computes BIS and other EEG parameters.     2.7   “BISx4” is an Aspect
device that acquires up to four channels of EEG and computes BIS and other EEG
parameters     2.8   “Documentation” means the BISx Serial Interface
Specification.     2.9   “Monitor Cable” is a cable that connects the BISx or
BISx4 to the Datascope Patient Monitor.     2.10   “Host Cable Connector” is the
connector that is or will be (as applicable) integrated into the Monitor Cable
for connection to the Datascope Patient Monitors.

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  2.11   “Datascope Patient Monitors” includes but not limited to multiparameter
patient monitoring systems and anesthesia machines manufactured and/or sold by
Datascope or its Affiliates under the Datascope brands designed for monitoring
patient vital signs in anesthetizing and sedating locations.     2.12  
“Datascope BISx System” is the combined Aspect BISx Kit and Monitor Cable.    
2.13   “Party” or “Parties” shall mean Aspect and Datascope each individually or
jointly.     2.14   “Software” means Aspect software programs in binary code
form that are designed for use with the Aspect BISx Kit.     2.15   “Mindray”
means Shenzen Mindray Bio-Medical Electronics Co., Ltd.

  2.   Section 4.3 of the Agreement shall be replaced by the following:        
Distribution of Aspect BIS Sensors

  4.3.1   Sensor Distribution         Aspect will provide Datascope one
(1) starter kit of demonstration sensors (five (5) sensors per kit as set forth
in Exhibit A (Aspect Products and Purchase prices)), at no charge with each
Datascope BISx System purchased. Datascope will provide this starter kit of five
(5) Aspect BIS Sensors at no charge with each Datascope BISx System sold to the
customer purchasing the corresponding Datascope BISx System.         Datascope
may [**] of Aspect BIS Sensors (twenty-five (25) sensors per box, except for
Bilateral which is ten (10) sensors per box, as set forth in Exhibit A) solely
in connection with the new sale of each Datascope BISx System and solely to the
customer purchasing the corresponding Datascope BISx System. Sensors are to be
delivered at time of Datascope BISx System installation.     4.3.2   Prices    
    Prices for Aspect BIS Sensors purchased by Datascope hereunder shall be as
set forth in Exhibit A (Aspect Products and Purchase Prices).

2/15

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  4.3.3   Aspect will ensure that Datascope customers have an outlet (which may
include Aspect or its Affiliates or a third party distributor) from which to
purchase BIS Sensors.  In the event Aspect does not provide such an alternative
BIS Sensor outlet in a country or region, Aspect (or its local Affiliate) will
grant Datascope or the applicable Datascope local Affiliate non-exclusive
distribution rights for BIS Sensors to Datascope customers in such country or
region with terms, conditions and pricing consistent with those of similar
distributors in other countries or regions offering the same level of marketing,
customer, and technical support as the local Datascope Affiliate is prepared to
offer.  Aspect shall have the right to terminate any such agreement upon three
(3) months notice once Aspect has established an alternative BIS Sensor outlet
for such country or region. Aspect will provide regular updates to Datascope
regarding the progress toward the establishment of alternative BIS Sensor
outlets.     4.3.4   If any sales by Datascope or its Affiliates, distributors
or sub-distributors of BIS Sensors are made to any customer in contravention of
Section 4.3.1, Datascope will cease such sales and Datascope will retroactively
pay Aspect an [**] for every BIS Sensor previously sold to customers in
contravention of Section 4.3.1. In addition, Datascope shall reimburse Aspect
for the cost of any audit that confirmed the existence of any such sales.

  3.   Section 6.1 “Commissions on Sales of Aspect BIS Sensors” is deleted    
4.   Section 7.6 “Competitive Products and Volume Price Discounts “ is added:  
      Competitive Products and Volume Price Discounts         If Datascope or
its Affiliates offer a directly competitive product to the Aspect BISx Kit (any
parameter that utilizes EEG to measure the hypnotic effect of anesthesia) the
volume discounts shown in Exhibit A [**].     5.   The following is added to the
end of Section 10 of the Agreement:         In the event that a new Datascope
BISx System (not repaired or refurbished product) is rejected by Datascope, and
Aspect replaces the product as remedy, the replacement product shall be a new
Datascope BISx System, not refurbished.         In the event that Datascope
rejects a service exchange Datascope BISx System, and Datascope provides written
notice to Aspect of the rejection within [**] days of the date of receipt,
Aspect shall in good faith, promptly upon receipt of written notification, and
in lieu of return receipt of the rejected service exchange Datascope BISx
System, send to Datascope a replacement service exchange Datascope BISx System.
Should Aspect’s subsequent examination and testing of the rejected service
exchange Datascope BISx System disclose that there was no defect covered by the
warranty set forth in Section 10, Aspect shall so advise Datascope and Aspect
may dispose of or otherwise handle the returned service

3/15

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      exchange Datascope BISx System at Aspect’s discretion, and Datascope shall
reimburse Aspect for transportation and insurance costs.

4/15

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  6.   Section 11.1 of the Agreement shall be replaced by the following:        
General         Aspect warrants solely to Datascope that Aspect Products
(including Software) delivered hereunder shall perform substantially in
accordance with the specifications in Exhibit B (Datascope’s BISx System) and
shall be free from defects in materials and workmanship, when given normal,
proper and intended usage, for [**] months from the date of shipment by Aspect
to Datascope. This warranty shall not apply to expendable components and supply
items, such as, but not limited to, cables (except for failures occurring within
[**] days of receipt of shipment by Datascope), or disposable items such as an
Aspect BIS Sensor after the expiration date marked on the Aspect BIS Sensor
packaging. Aspect shall not have any obligation under this Agreement to make
repairs or replacements which are required by normal wear and tear, or which
result, in whole or in part, from catastrophe, fault or negligence of Datascope
or Affiliate, or anyone claiming through or on behalf of Datascope, or from
improper or unauthorized use of Aspect Products, or use of Aspect Products in a
manner for which they were not designed, or by causes external to Aspect
Products such as, but not limited to, power or air conditioning failure.     7.
  Section 11.2 of the Agreement shall be replaced by the following:        
Warranty Procedures         Datascope shall notify Aspect of any Aspect products
which it believes to be defective during the applicable warranty period and
which are covered by the warranties set forth in Section 11.1. At Aspect’s
option, such Aspect Products shall be returned by Datascope to Aspect’s
designated facility for examination and testing, or may be repaired on site by
Aspect. Aspect shall either repair or replace, within [**] of receipt by Aspect,
any such Aspect Product found to be defective and return these Aspect Products
to Datascope. Transportation and insurance costs shall be borne by Aspect.
Should, Aspect’s examination and testing disclose that there was no defect
covered by the foregoing warranty, Aspect shall so advise Datascope and dispose
of or return the Aspect Product in accordance with Datascope’s instructions and
at Datascope’s expense, and Datascope shall reimburse Aspect for transportation
and insurance costs.     8.   Section 12.2 of the Agreement shall be replaced by
the following:         Service Training         Aspect agrees to provide initial
service training, [**] to Datascope, to a mutually agreed upon number of
Datascope service representatives prior to the market release of the BISx
Systems         If there are Aspect Product changes that materially affect form,
fit, or function, as described in Section 15, and based on the mutual
understanding of the necessity of the training, Aspect shall provide [**]
training to a mutually agreed upon number of Datascope personnel, at a mutually
agreed upon schedule, [**] to Datascope.

5/15

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  9.   Section 14.7 of the Agreement shall be replaced by the following        
Recall         In the event that a corrective action (including notifications or
recalls) is initiated with respect to any Aspect Product, and such action (i) is
required to comply with applicable laws or regulations, (ii) is initiated by
Aspect in its discretion for a reasonable business purpose or for safety reasons
or (iii) is the result of the failure of Aspect Products to conform in all
material respects to the applicable standards, Aspect shall be responsible for
the repair or replacement of the Aspect Products without cost to Datascope.
Aspect agrees to consult with Datascope to establish a reasonable process for
managing the corrective action and Aspect shall be responsible for all
reasonable out-of-pocket expenditures incurred by Datascope if Aspect fails to
take corrective action. In the event that Aspect or Datascope is required to
take such action to comply with applicable laws or regulations or such action is
reasonably necessary for safety and efficacy reasons or for the failure of the
Aspects Products to comply with specifications (other than minor deviations from
specifications) and fails to do so within 10 days of being notified of the need
for such action, Datascope shall have the right to take such action and Aspect
shall reimburse Datascope for all reasonable out-of-pocket expenditures incurred
in connection with such action by Datascope. If it is determined by an
arbitrator that such action was not necessary for safety reasons or for the
failure of Aspect Products to comply with specifications (other than a minor
deviation from such specifications), Datascope will return to Aspect any amounts
previously paid to Datascope by Aspect in connection with such action.        
Any corrective action will be at Datascope’s expense if clearly caused by the
Datascope Patient Monitor. Datascope will reimburse Aspect for Aspect’s
documented cost directly resulting from such corrective actions within sixty
(60) days of completion of the corrective action.         Datascope and Aspect
will share the cost if both Parties’ products contribute to the cause,
proportionate to the extent of each Party’s respective degree of cause as
mutually agreed. Aspect and Datascope will negotiate in good faith a reasonable
settlement of the issue. If after twenty (20) business days, the Parties in good
faith fail to agree the issue will be escalated for resolution in accordance
with Section 22.     10.   Section 22.1 of the Agreement shall be replaced by
the following         Term and Renewal         The initial term of this
Agreement shall commence on the date first set forth above and shall continue
for an initial period until October 25, 2009. The term of this Agreement shall
thereafter be renewed automatically for successive twelve (12) month periods,
unless either Party provides written notice of termination to the other Party at
least ninety (90) days prior to expiration of the Agreement.     11.   Exhibits
of the Agreement shall be replaced as follows:

  a)   “Exhibit A: Aspect Products and Purchase Prices” is replaced by the
attached “Exhibit A: Aspect Products and Purchase Prices”.

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  b)   “Exhibit B: Specifications: Datascope BISx System” is replaced by the
attached “Exhibit B: Specification: Datascope BISx System”.     c)   “Exhibit C:
Contact Persons / Addresses” is replaced by the attached “Exhibit C: Contact
Persons / Addresses”.     d)   “Exhibit D: Aspect and Datascope Trademarks” is
replaced by the attached “Exhibit D: Aspect and Datascope Trademarks”.

All terms and conditions of the Agreement not modified herein shall remain
unchanged, in full force and effect. After the Amendment Effective Date, every
reference in the Agreement to the “Agreement” shall mean the Agreement as
amended by this Amendment 2.
Acceptance of this Amendment 2 is indicated by signatures below.

                  Aspect Medical Systems, Inc.   Mindray DS USA, Inc.      
By:
  /s/ J. Neal Armstrong   By:   /s/ Tim Fitzpatrick    
 
 
 
     
 
   
 
               
Date:
  11-5-09   Date:   2 November 2009    
 
 
 
     
 
   
 
               
Name:
  Neal Armstrong   Name:   Tim Fitzpatrick    
Title:
  Chief Financial Officer   Title:   Corporate Secretary    

7/15

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EXHIBIT A
ASPECT PRODUCTS AND PURCHASE PRICES
A) Datascope BISx System:

                                     Aspect   Datascope           Unit of    
Part Number   Part Number   Product Description   Measure   List Price
186-0195-DS
  0992-00-0236-01     BISx Kit (Datascope)   1 each   [**]  
186-0224-DS (†)
  TBD     BISx4 Kit (Datascope)   1 each   [**]  

 

(†)   Estimated price, assumes a standard Datascope monitor cable and host cable
connector. Customization of monitor cable or host cable connector may increase
costs. BISx4 Kit development costs will be determined by the terms and
conditions of Section 7 the Agreement.

B) Volume Discounts

                                                                      Total
Price for   Total Price for Cumulative Annual Total                   Price for
  Datascope BISx   Datascope BISx4 Volume (in units) ‡   Price for   Price for  
Monitor   System   System (Calendar Year)   BISx Kit   BISx4 Kit   Cable  
186-0195-DS   186-0224-DS(†)
[**]
    [**]       [**]       [**]       [**]       [**]  
[**]
    [**]       [**]       [**]       [**]       [**]  
[**]
    [**]       [**]       [**]       [**]       [**]  

 

(†)   Estimated price, assumes a standard Datascope monitor cable and host cable
connector. Customization of monitor cable or host cable connector may increase
costs. BISx4 Kit development costs will be determined by the terms and
conditions of Section 7 the Agreement.   ‡   Total calculation includes all
Datascope BISx System types purchased by Datascope under this Agreement
(186-0195-DS and BISx4 Kits), as well as [**]. Cumulative means the combination
of volume of Mindray and [**].  Pricing from the Amendment Effective Date
through [**] will be at the [**] level. Pricing for subsequent years will be as
defined in section E of this Exhibit A.

C) BIS DISPOSABLE SENSORS

                                    Aspect   Datascope           Unit of  
Datascope Part Number   Part Number   Product Description   Measure   Price
186-0106*
  0600-00-0132-01     BIS Quatro Sensor   Box of 25   [**]  
186-0200*
  0600-00-0132-03     BIS Pediatric Sensor   Box of 25   [**]  
186-0160*
  0600-00-0132-02     BIS Extend Sensor   Box of 25   [**]  
186-0212*
  TBD   BIS Bilateral Sensor   Box of 10   [**]  

 

*   Datascope may distribute [**] of sensors (1 box = 25 sensors, except for
Bilateral where 1 box = 10 sensors) bundled with the sale of the Datascope BISx
System, as set forth in Section 4.3.

     ii) Demonstration sensors:

                  Aspect   Datascope       Unit of   Datascope Part Number  
Part Number   Product Description   Measure   Price
186-0150-DS**
  0020-00-0491-01   BIS Quatro Starter Kit   Box of 5   [**]
186-0206-DS**
  0020-00-0491-03   BIS Pediatric Starter Kit   Box of 5   [**]

 

**   Demonstration sensors cannot be resold

8/15

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D) SPARE PARTS/ACCESSORY PRICES

                              Datascope   Orderable   Unit of   Aspect  
Datascope Aspect Part #   Part Number   Parts/Products   Measure   List Price  
Price
186-0142-DS
  0012-00-1666-01   DS PIC+ Cable
(replacement)   1 each   $ 125.00     [**]
186-0201-DS
  0012-00-1665-01   Datascope Host Cable
(Replacement)   1 each           [**]
186-1018-DS
  TBD   DS PIC4 Cable
(replacement)   1 each   $ 200.00     [**]
186-0143-DS
  0454-00-0060   DS 2ch & 4ch Sensor
Simulator   1 each   $ 30.00     [**]

                          Aspect Part   Datascope   Orderable   Unit of   Aspect
  Datascope Number   Part Number   Parts/Products   Measure   List Price   Price
186-0199-DS (••)
  0992-UC-0236-01   Datascope BISx Kit
(service exchange)   1 each   $ 1,500.00     [**]
186-1030-DS (†) (••)
  TBD   Datascope BISx4 Kit
(service exchange)   1 each   $ 2,300.00     [**]

 

(†)   Estimated price, assumes a standard Datascope monitor cable and host cable
connector. Customization of monitor cable or host cable connector may increase
costs. BISx4 Kit development costs will be determined by the terms and
conditions of Section 7 the Agreement.   (••)   Service exchange items may be
refurbished product. Service exchange items can only be ordered in qty equal to
Return Material Authorization Numbers (RMA#s) issued by Aspect. See Section 11.2
of the Agreement for details on Warranty procedures. Units exchanged under
warranty may be replaced with a comparable refurbished product and carry a
Repair Warranty as outlined in Section 11.3 of the Agreement.

E) CALCULATION OF VOLUME DISCOUNT:
For the purpose of calculating the volume discount for a given calendar year,
all BISx/BISx4 Kits purchased by [**], excluding Aspect Products that are
shipped free of charge, will be included in the total volume discount
calculation.
The initial pricing for a given calendar year is based on the total volume of
BISx/BISx4 Kits purchased in the prior calendar year. For example, if [**] BISx
Kits were purchased in year 1, the initial volume pricing level for year 2 will
be the [**] unit price level. The Parties agree that, for the period beginning
on the Amendment Effective Date and continuing through [**], pricing will start
at the [**] unit price level.
If a higher volume level of BISx/BISx4 Kits is achieved during a given calendar
year, the price on only those BISx/BISX4 Kits purchased after achieving the
higher volume level will reflect the price associated with the appropriate
volume level achieved. All price adjustments will apply on a going forward basis
only. For example, if midway through year 2, [**] BISx Kits are purchased, the
price on the [**] BISx Kit will reflect the next volume break.
     F) CURRENCY
United States Dollars

9/15

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EXHIBIT B
SPECIFICATIONS: DATASCOPE BISx SYSTEM
(IMAGE) [b77440b7744001.gif]
PRODUCT DESCRIPTION
The BISx Kit includes a PIC+, BISx Device, and a Monitor Cable. The BISx kit
will here forth be referred to as BISx. The BISx4 Kit includes a 4 channel PIC,
BISx4 Device, and a Monitor Cable. The BISx4 kit will here forth be referred to
as BISx4.
BISx is a device that acquires up to two channels of EEG and computes BIS and
other EEG parameters. BISx4 is a device that acquires up to four channels of EEG
and computes BIS and other EEG parameters. Both the BISx and BISx4 are designed
to mate with Aspect’s XP platform 1 or 2 channel sensors. The BISx4 is designed
to additionally interface with Aspect’s Bilateral sensor, which is required for
acquisition of 4 channels of EEG. BISx and BISx4 have no display or user
interface. They plug into a host monitor system for display of EEG and processed
parameters. BISx and BISx4 are designed for use wherever sedative drugs are
administered, including but not limited to the following environments: Operating
rooms, Intensive Care Units, Procedural Sedation, and Clinical Research areas.
BISx and BISx4 interface to one or more of the following interfaces: standard
RS-232 asynchronous interface, RS-232 type asynchronous interface but with TTL
3.3V signal levels, RS-485, or Universal Serial Bus (USB) interface. All
interface versions also support USB interfacing for software upgrade and
download purposes. BISx and BISx4 can be connected and disconnected to an
already powered up host monitor. The host monitor should automatically detect
its presence and configure it accordingly.

10/15

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The BISx connects to a sensor via the Aspect Patient Interface Cable (here forth
referred to as PIC+). The PIC+ is nominally 4.5 ft. long. The PIC+ connection is
integral to the enclosure (no pigtail), and can be detached from the BISx device
for service or replacement without the use of tools. The enclosure is sealed
against liquid ingress even when the PIC+ is detached.
The BISx4 connects to a sensor via the Aspect 4 channel Patient Interface Cable
(here forth referred to as CM PIC). The CM PIC is nominally 54 inches long. The
CM PIC connection is integral to the enclosure (no pigtail), and can be detached
from the BISx4 device for service or replacement without the use of tools. The
enclosure is sealed against liquid ingress even when the PIC+ is detached.
The BISx or BISx4 is attached to the host monitoring system via a nominal 9-foot
monitor cable. The host connector of the monitor cable is host system dependent
and is the source of future development with Datascope. The wire is narrow and
highly flexible multi-conductor cable used to supply power from the host monitor
to the BISx/BISx4 as well as allow communication between the devices.
Additionally, the inability of the host monitor to provide the BISx specified
power requirements or communication requirements may be addressed through the
inclusion of a circuit which is integral to the monitor cable.
The monitor cable connection to the BISx/BISx4 device is integral to the
enclosure (no pigtail), and may require the use of tools for detachment from the
BISx/BISx4 device enclosure for the purposes of service or replacement. The
enclosure is sealed against liquid ingress only when the monitor cable is
attached. There are no adjustable parts inside the BISx. The cables may be
replaced without opening the enclosure.
The BISx and BISx4 include software which is stored in reprogrammable FLASH
memory. Software upgrades can be accomplished via the serial / USB interface.
Each BISx and BISx4 is given a unique serial identifier, allowing for electronic
identification and tracking of every BISx/BISx4.
PRELIMINARY TECHNICAL SPECIFICATIONS (Unless otherwise noted specifications
apply to both the BISx and BISx4)
Physical Specifications
BISx Kit
Size: 95.3 mm (3.75”) diameter x 63.5 mm (2.5”) height
Weight: approx 8.0 oz without cables
     approx 10.0 oz including PIC+
BISx Integral Cables
Host Monitor Cable: 2.74m (9ft)
Patient Interface Cable (PIC+): 1.4m (4.5 ft)

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BISx4 Kit
Size: 95.3 mm (3.75”) diameter x 63.5 mm (2.5”) height
Weight: 227g (8.0 oz) without cables
BISx4 Integral Cables
Host Monitor Cable: 2.74m (9ft)
Patient Interface Cable (CM PIC): 1.4m (4.5 ft)
Safety Specifications

  •   The BISx and BISx4 comply with the essential requirements of the Medical
Device Directive 93/42/EEC, as well as IEC 60601-1 and IEC 60601-2-26.     •  
They are both Type BF applied parts. Both the BISx and BISx4 have internal
optical coupling and an isolation transformer for patient isolation.     •  
Both are protected against damage from defibrillation as long as the sensor is
not located between the defibrillator pads and is resistant to artifact from
electrosurgery.     •   United States federal law restricts these devices to
sale by or on the order of a physician.     •   BISx, BISx4, and cables are
latex free.

Environmental Specifications
Liquid Ingress: IEC 529 IPX4
Temperature
0 to 40 degrees C operating
-40 to 70 degrees C storage
               Humidity
10% to 95% non-condensing operating
10% to 95% non-condensing storage
Pressure
480 to 1067 hPa operating (Approx -1250 to 20,000 feet)
116 to 1067 hPa storage (Approx -1250 to 50,000 feet)
Performance Specifications
Measurement Ranges
Bispectral Index (BIS): 0 to 100 unitless scale
Electromyographic Strength (EMG): 25 to 100 dB where 1 µV2=40dB
Signal Quality Index (SQI): 0 to 100%
Suppression Ratio (SR): 0 to 100%
Spectral Edge Frequency (SEF): 0.5 to 30.0 Hz
Total Power: 40 to 100 dB where 1 µV RMS=40dB
Burst Count: 0 to 30
Noise (EEG Waveform) < 0.3 µVRMS (2.0 µV peak-to-peak)
BIS Numeric Update Frequency Once per second
EEG Bandwidth 0.25 to 100 Hz (- 3dB)
Patient Leakage <10uA

12/15

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EXHIBIT C
CONTACT PERSONS/ADDRESSES
Contact Persons and Responsibilities at Aspect:

              Person   Title   Responsibility   Email
Joan Rubin
  Sr. Director,   Contract   jrubin@aspectms.com
 
  Business        
 
  Development        
 
           
Steve Mesrobian
  Director, OEM   Project Manager   smesrobian@aspectms.com
 
  Engineering        
 
           
Christine Vozella
  Senior Director,   Quality and   cvozella@aspectms.com
 
  RA/QA   Regulatory Matters    
 
           
James Charest
  OEM Engineer Manager   Technical Design   jcharest@aspectms.com
 
      Issues    

           
Mailing Address:
  Aspect Medical Systems, Inc.
 
  One Upland Road
 
  Norwood, MA 02062

Contact Persons and Responsibilities at Datascope:

              Person   Title   Responsibility   Contact Information
Richard Cipolli
  Engineering Manager   Project Manager,   E-mail:
 
      Spectrum O.R.   richard_cipolli@datascope.com
 
          Tel: 1-201-995-8024
 
          Fax: 1-201-995-8654
 
           
Bonita Lisnay
  Purchasing   Purchasing   E-mail:
 
  Supervisor       bonita_lisnay@datascope.com
 
          Tel: 1-201-995-8374
 
          Fax: 1-201-995-8001
 
           
Chuck Webster
  Director of   Marketing   E-mail:
 
  Marketing & Sales       chuck_webster@datascope.com
 
  Solutions       Tel: 1-201-995-8207
 
          Fax: 1-201-995-8612
 
           
Kathleen Kramer
  Supervisor,   Regulatory   E-mail:
 
  Clinical and       kathleen_kramer@datascope.com
 
  Regulatory Affairs       Tel: 1-201-995-8169
Fax: 1-201-995-8605

         
Address:
  Mindray DS USA, Inc.  
 
  800 MacArthur Blvd  
 
  Mahwah, NJ 07430  

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EXHIBIT D
ASPECT AND DATASCOPE TRADEMARKS

      Aspect Trademarks   Reference
Aspect ®
  Aspect is a registered trademark of Aspect Medical Systems, Inc
 
   
A-2000 TM
  A-2000 is a trademark of Aspect Medical Systems, Inc.
 
   
Bispectral Index ®
  Bispectral is a registered trademark of Aspect Medical Systems, Inc.
 
   
BIS ®
  BIS is a registered trademark of Aspect Medical Systems, Inc.
 
   
(BIS LOGO) [b77440b7744002.gif]
  BIS logo is a registered trademark of Aspect Medical Systems, Inc.
 
   
BISx ™
  BISx is a trademark of Aspect Medical Systems, Inc.
 
   
BIS Ready™
  BIS Ready is a trademark of Aspect Medical Systems, Inc.
 
   
BIS VISTA ™
  BIS VISTA is a trademark of Aspect Medical Systems, Inc.
 
   
(BIS LOGO) [b77440b7744003.gif]
  BISx logo is a trademark of Aspect Medical Systems, Inc.
 
   
(BIS LOGO) [b77440b7744004.gif]
  BIS Ready logo is a registered trademark of Aspect Medical Systems, Inc.

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      Datascope Trademarks   Reference
(DATASCOPE LOGO) [b77440b7744005.gif]
  Datascope logo is a U.S. registered trademark of Datascope Corp.
 
   
Datascope®
  Datascope® is a U.S. registered trademark of Datascope Corp.
 
   
Navigator™
  Navigator™ is a U.S. trademark of Datascope Corp.
 
   
Panorama™
  Panorama™ is a U.S. trademark of Datascope Corp.
 
   
Spectrum™
  Spectrum™ is a U.S. trademark of Datascope Corp.
 
   
View 12™
  View 12™ is a U.S. trademark of Datascope Corp.
 
   
Passport 2®
  Passport 2® is a U.S. registered trademark of Datascope Corp.
 
   
Auto-Set™
  Auto-Set™ is a U.S. trademark of Datascope Corp.
 
   
Rescale Waves™
  Rescale Waves™ is a U.S. trademark of Datascope Corp.
 
   
SmartScreen™
  SmartScreen™ is a U.S. trademark of Datascope Corp.

Further Datascope Trademark information to be provided by Datascope within
30 days of signing amendment.

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