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June 13, 2014
Re:
Member of the Board of Directors of Chimerix, Inc.

Dear Catherine:
It is my sincere pleasure, on behalf of Chimerix, Inc. (“Chimerix”), to offer
you a position as a member of the Board of Directors (the “Board”) of Chimerix,
contingent and effective upon your formal approval by the Board at a meeting to
take place on June 20, 2014 and your acceptance of the terms of this offer.
As compensation for your service as a member of the Board, you will receive a
$35,000 annual retainer. You will also be granted a nonqualified stock option to
purchase 18,000 shares of common stock pursuant to our 2013 Equity Incentive
Plan (the “Plan”), at an exercise price equal to the closing price of Chimerix’s
common stock on the date of grant, which would occur on the later of June 20,
2014 and your acceptance of this offer. One-fourth of the shares subject to this
option will vest on the one year anniversary of the date of grant and the
balance of the shares will vest in a series of 36 equal monthly installments
thereafter, such that the option will be fully vested on the fourth anniversary
of the date of grant, subject to your continued service.
With your continued service on the Board you will be compensated in accordance
with the terms of the Chimerix, Inc. Non-Employee Director Compensation Policy.
Chimerix will also reimburse you for reasonable out-of-pocket travel expenses
incurred in connection with your attendance at Board meetings.
If the terms of this letter are acceptable to you and you agree to serve as a
member of the Board if appointed, please sign and date this letter below and
return it to us via PDF, retaining a copy for your records.
Very truly yours,
/s/ M. Michelle Berrey
M. Michelle Berrey
President, Chief Executive Officer and Chief Medical Officer
Chimerix, Inc.

Accepted and agreed:

/s/ Catherine Gilliss    
Catherine L. Gilliss

Date:     6/16/14