Synthetic Blood International, Inc.
3189 Airway Avenue, Building C
Costa Mesa, CA 92626

To:
Dr. Bruce Spiess
620 Dover Bluff Ct.
Manakin-Sabot, VA 23103

Engagement Letter

Dear Bruce:

Subject to our by-laws we herewith confirm your engagement as a director and a
member of the board of our company (SYBD).

We agreed that monetary compensation shall be through a consulting contract with
you.

Independent of the aforementioned consulting contract, we will pay you the
following stock compensation for your services (earlier option award):

Stock options (3 years life), exercisable at a price of $0.30, as follows:
300,000 with this appointment to the board of directors;
300,000 at closing of a license agreement, or sale of the company within 24
months after appointment to the board of directors.

As discussed, the board may discuss and decide on an expansion of this agreement
at its next meeting.

With regard to the services to be performed by you pursuant to the terms of this
engagement, you shall not be liable to SYBD, or to anyone who may claim any
right due to any relationship with SYBD, for any acts or omissions in the
performance of services on your part. SYBD shall hold your free and harmless
from any obligations, costs, claims, judgments, attorneys' fees, and attachments
arising from or growing out of the services rendered to SYBD pursuant to the
terms of this agreement or in any way connected with the rendering of services,
except when you are adjudged to be guilty of willful misconduct or gross
negligence by a court of competent jurisdiction. SYBD shall maintain an
appropriate director’s and officer’s (D&O) insurance at all times and cover you
under such a policy.

Sincerely,
Synthetic Blood International, Inc. (SYBD) Accepted:   By: Chris Stern Date:
3/24/08 Bruce Spiess           Date:

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