Exhibit 10.2
AMENDMENT TO STOCKHOLDERS AGREEMENT
     This AMENDMENT TO STOCKHOLDERS AGREEMENT, dated as of June 26, 2009 (this
“Amendment”), is by and among CHIESI FARMACEUTICI SPA, a corporation organized
under the laws of Italy, CRAIG A. COLLARD, CORNERSTONE BIOPHARMA HOLDINGS, LTD.,
a limited liability company organized under the laws of Anguilla, CAROLINA
PHARMACEUTICALS LTD., a limited liability company organized under the laws of
Bermuda, LUTZ FAMILY LIMITED PARTNERSHIP, North Carolina limited partnership,
STEVEN M. LUTZ and CORNERSTONE THERAPEUTICS INC., a Delaware corporation (the
“Company”).
RECITALS
     WHEREAS, the parties entered into a Stockholders Agreement, dated as of
May 6, 2009 (the “Stockholders Agreement”); and
     WHEREAS, the parties desire to amend the Stockholders Agreement in certain
respects.
     NOW, THEREFORE, in consideration of the foregoing and other good and
valuable consideration, the receipt and adequacy of which are hereby
acknowledged, the parties hereto agree as follows:
     1. Annex A to the Stockholders Agreement is hereby deleted in its entirety
and replaced with the Annex A attached hereto.
     2. This Amendment may be executed in counterparts, each of which shall be
deemed an original, but all of which together shall constitute one and the same
instrument.
[Remainder of this page is intentionally left blank.]

 

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     IN WITNESS WHEREOF, the parties have executed this Amendment as of the date
first written above.

            CORNERSTONE THERAPEUTICS INC.
      By:   /s/ David Price        Name:   David Price       Title:   Chief
Financial Officer       CHIESI FARMACEUTICI SPA
      By:   /s/ Alberto Chiesi        Name:   Alberto Chiesi       Title:  
President    

[Signature Page to Amendment to Stockholders Agreement]

 

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                   /s/ Craig A. Collard       Craig A. Collard               
CORNERSTONE BIOPHARMA HOLDINGS, LTD.
      By:   /s/ Craig A. Collard        Name:   Craig A. Collard       Title:  
CEO       CAROLINA PHARMACEUTICALS LTD.
      By:   /s/ Craig A. Collard       Name:   Craig A. Collard       Title:  
CEO    

[Signature Page to Amendment to Stockholders Agreement]

 

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                   /s/ Steven M. Lutz       Steven M. Lutz                LUTZ
FAMILY LIMITED PARTNERSHIP
      By:   STEVEN M. LUTZ, its general partner                /s/ Steven M.
Lutz       Steven M. Lutz             

[Signature Page to Amendment to Stockholders Agreement]

 

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ANNEX A
COVERED SHARES

              Number of Covered Stockholder   Shares
Craig A. Collard
    228,559  
Cornerstone Biopharma Holdings, Ltd.
    1,561,780  
Carolina Pharmaceuticals Ltd.
    947,207  
Lutz Family Limited Partnership
    261,878  
Steven M. Lutz
    195,227