March 4, 2010
Via Federal Express
Senesco Technologies, Inc.
303 George St., Suite 420
New Brunswick, New Jersey 08901
Attention:  Joel Brooks, Chief Financial Officer

Re:  Senesco Technologies, Inc.

Mr. Brooks:

In accordance with the terms of those certain secured convertible debentures, as
set forth in detail on Schedule A attached hereto, (the “Notes”) which were
issued in connection with that certain Securities Purchase Agreement, dated
August 29, 2007, by and between Senesco Technologies, Inc. and Stanford Venture
Capital Holdings, Inc. (“Stanford”) as such Notes were further sold to the
undersigned (the “Holders”) pursuant to that Purchase and Sale Agreement dated
as of November 6, 2009 by and between Stanford and the Holders, the Holders,
jointly and severally, hereby acknowledge and agree as follows:

 
1.
The Notes shall be converted into shares of Company common stock, par value
$0.01,  (the “Conversion Shares”) at a price per share price of $0.83
immediately following the receipt of the approval of the stockholders of the
Company at a meeting called for such purpose (the “Conversion Date”).

 
2.
Issuance of the Conversion Shares shall be in exchange for and in full
satisfaction of the Company’s obligations under the Notes.  Immediately
following the issuance of the Conversion Shares, the Notes shall be
automatically cancelled and shall be of no further force or effect.

 
3.
Promptly following the Conversion Date, the Holders will return to the Company
the originally executed Notes marked cancelled.

 
 

 
[End of text.]
 

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IN WITNESS WHEREOF, the signatories hereto have executed this letter as of the
date set forth above.

 
By:  /s/ Christopher Forbes
 
Christopher Forbes
             
By:  /s/ Rudolf Stalder
 
Rudolf Stalder
             
By:  /s/ Harlan W. Waksal, M.D.
 
Harlan W. Waksal, M.D.
             
By:  /s/ David Rector
 
David Rector
             
By:  /s/ John N. Braca
 
John N. Braca
             
By:  /s/ Jack Van Hulst
 
Jack Van Hulst
             
By:  /s/ Warren Isabelle
 
Warren Isabelle
         
THOMAS C. QUICK CHARITABLE FOUNDATION
             
By: /s/ Thomas C. Quick
 
Name: Thomas C. Quick
 
Title:

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Schedule A
 
 
 
 

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