QuickLinks -- Click here to rapidly navigate through this document

Exhibit 10.10

Axcelis Technologies, Inc.
Named Executive Officer Base Compensation at March 1, 2008

        This Exhibit discloses the current understandings with respect to base
compensation between Axcelis Technologies, Inc. (the "Company") and each of:

•the Company's principal executive officer (Mary G. Puma),

•the Company's principal financial officer (Stephen G. Bassett), and

•the three most highly compensated other executive officers serving as executive
officers at December 31, 2007.

        These executive officers are referred to herein as "named executive
officers" or "NEOs."

        Other than in the case of Mary G. Puma, the Company has not entered into
any written agreements with its named executive officers addressing the amount
of base salary due to the executive. The Company's Amended and Restated
Employment Agreement with Ms. Puma is listed as Exhibit 10.12 to this Form 10-K
(incorporated by reference to Exhibit 10.3 to the Company's Form 10-Q for the
quarter ended September 30, 2007 filed on November 8, 2007). The Company
maintains that all executive officers, other than Ms. Puma, are employees at
will and that the Company has no obligation to pay base salary, other than
amounts accrued for services rendered prior to termination of employment and
other than in circumstances where the Change of Control Agreements described in
our Proxy Statement and filed as an Exhibit to this Form 10-K are applicable.

        In the course of the employment relationship with each NEO, the Company
communicates to the named executive officer the amount of base salary approved
by the Compensation Committee of the Board of Directors, which compensation is
subject to change in the discretion of the Compensation Committee of the Board
of Directors. The following table sets forth the annual base salary as
communicated to the named executive officers of the Company as in effect on
March 1, 2008:

Named Executive Officer

--------------------------------------------------------------------------------

  Title

--------------------------------------------------------------------------------

  Base Salary

--------------------------------------------------------------------------------

Mary G. Puma   President and Chief Executive Officer   $ 500,000 Stephen G.
Bassett   Executive VP and Chief Financial Officer   $ 300,000 Matthew Flynn  
Executive VP, Global Customer Operations   $ 350,000 Lynnette C. Fallon  
Executive VP, HR/Legal and General Counsel   $ 305,000 Kevin Brewer   Senior VP,
Manufacturing Operations   $ 275,000

--------------------------------------------------------------------------------

QuickLinks

Exhibit 10.10

Axcelis Technologies, Inc. Named Executive Officer Base Compensation at March 1,
2008