Exhibit 10.1

TERMINATION OF
CONSULTING AGREEMENT

Reference is made to the Consulting Agreement dated October 4, 2004 between
MOMENTA PHARMACEUTICALS, INC., (the “Company”) and Bennett M. Shapiro
(“Consultant”), as amended (collectively, the “Agreement”).  Capitalized terms
used herein and not otherwise defined shall have the meanings given such terms
in the Agreement.

The parties hereby agree to terminate Agreement effective as of March 30, 2007. 
Notwithstanding anything to the contrary, Sections 3 (Developments) and 4
(Confidentiality) shall survive such termination.

Agreed to as of the date of last signature below.

CONSULTANT

 

MOMENTA PHARMACEUTICALS, INC.

/s/ Bennett M. Shapiro

 

By:

/s/ Craig A. Wheeler

Bennett M. Shapiro

 

Print Name: Craig A. Wheeler

Date:

 

Title: President & CEO

 

 

Date: March 30, 2007

 

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