Exhibit 10.1

FIRST AMENDMENT OF LEASE

This First Amendment of Lease (this “Amendment”) is made and entered into on
this the 10 day of November, 2017, by and between Pearland Economic Development
Corporation (“Landlord”) and Cardiovascular Systems, Inc., (“Tenant”).

RECITALS

A.Whereas, Landlord and Tenant entered into that certain Lease dated September
4, 2009 (the “Lease”) relating to approximately 46,000 square feet of floor area
on the Leased Premises located at 14740 Kirby Drive, in Pearland, Harris County,
Texas; and

B. Whereas, pursuant to the Lease, Tenant’s First Expansion Option and Second
Expansion Option have expired and Tenant’s Expansion Options under the Lease
have therefore been waived; and

C.Whereas, Landlord may have the opportunity to sell a portion of the Leased
Premises that comprises a portion of the First Expansion Option Land as more
accurately depicted on Exhibit A attached hereto (the “Adjacent Property”); and

D. Whereas, in exchange for Tenant’s willingness to remove the Adjacent Property
from the Leased Premises, Landlord is willing to use proceeds from the sale of
the Adjacent Property to construct no fewer than thirty (30) additional parking
improvements on the Leased Premises in accordance with Exhibit B attached hereto
to exclusively serve Tenant (the “Parking Improvements”); and

E.    Landlord and Tenant now desire to amend certain terms of the Lease for the
consideration and upon the terms and conditions hereinafter expressed.

NOW THEREFORE, for and in consideration of the mutual covenants and agreements
herein contained, and other good and valuable consideration, the receipt and
adequacy of which are hereby expressly acknowledged, Landlord and Tenant hereby
amend the Lease as follows:

1.
Recitals. The Recitals are hereby incorporated herein by reference. Capitalized
terms used herein shall have the meanings given to them in the Lease unless
otherwise defined herein.

2.
Sec. 1 Leased Premises. The Leased Premises shall be redefined as: (i) the tract
of land in Pearland, Texas (the “Land”), more particularly depicted on Exhibit A
attached hereto, together with any and all easements, rights and appurtenances
appertaining to same, and (ii) that certain building (the “Building”) previously
constructed by Landlord and containing approximately 46,000 square feet. For
greater certainty, Landlord and Tenant agree that the term “Leased Premises”
shall include, but not be limited to, the Improvements.

3.
Sec. 51 Purchase Option. Tenant’s Purchase Option set forth in Section 51 of the
Lease shall only apply to the redefined Leased Premised depicted on Exhibit A
attached hereto.

4.
Sec. 54 Tenant’s Right of First Refusal. Tenant’s right of first refusal set
forth in Section 54 of the Lease shall only apply to those portions of the First
Expansion Option Land not included in the Adjacent Property as depicted on
Exhibit A attached hereto.

5.
Parking Improvements – Landlord, at its sole cost and expense, shall construct
the Parking Improvements on the Leased Premises. Landlord shall commence
construction of the

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Exhibit 10.1

Parking Improvements within one hundred eighty (180) days following Landlord’s
sale of the Adjacent Property and complete the Parking Improvements no later
than two hundred forty (240) days after commencement of construction. If
Landlord fails to commence or complete the Parking Improvements within the
applicable timeframes, then Tenant, in addition to all rights and remedies
available under the Lease upon Landlord’s default, shall have the rights set
forth in Section 55 of the Lease.

6.
Platting – Prior to Landlord’s sale of the Adjacent Property, Landlord shall
replat the Leased Premises and the Adjacent Property in accordance with City of
Pearland platting requirements, including the dedication of all necessary
easements. Tenant agrees cooperate with Landlord to effectuate the replatting of
Landlord’s Property to carry out the terms of this Lease Amendment, and no
required approvals from Tenant shall be unreasonably withheld; provided,
however, in no event shall the replat adversely affect (a) Tenant’s ability to
access the Leased Premises or (b) Tenant’s business operations at the Leased
Premises.

7.
Contingency – The terms of this Lease Amendment shall be contingent upon
Landlord’s closing on the sale of the Adjacent Property on or before June 1,
2018. Landlord shall provide to Tenant written notice of the closing of such
sale within five (5) days of the closing date. If such closing does not occur on
or before June 1, 2018, then this Amendment shall be null and void.
Notwithstanding the foregoing, Landlord’s obligations to make the Building
Repairs, as defined in Section 8 herein, shall not be contingent on the sale of
the Adjacent Property and shall survive any termination of this Amendment.

8.
Building Repairs – Landlord, at its sole cost and expense, shall have all
repairs completed as presented in Exhibit C by February 28, 2018 (the “Building
Repairs”). If Landlord fails to complete the Building Repairs by February 28,
2018, then Tenant, in addition to all rights and remedies available under the
Lease upon Landlord’s default, shall have the rights set forth in Section 55 of
the Lease.

9.
Building Finish Floor:  The parties acknowledge that certain cracks exist in the
finish floor of the Building.   Tenant will hire a structural engineer to
monitor the finish floor annually. If the engineering assessment, utilizing
L/360 guidelines, discloses any movement or deflection of the Finish Floor the
Tenant will present its findings to the Landlord and the parties will work on
corrective measure to ensure there is no adverse affect on Tenant’s ability to
use and operate the Leased Premises. If Landlord and Tenant are unable to come
to an agreement, then Tenant, in addition to all rights and remedies available
under the Lease, shall have the rights set forth in Section 55 of the Lease.

10.
Section 49 Renewal Options –

a.
The first paragraph of Section 49 shall be amended to read as follows: “Tenant
shall have, and is hereby granted, the options (the “Renewal Options”) to extend
the Term of this Lease Agreement for three (3) consecutive additional periods
(as applicable, the “Extended Term”). The first Extended Term shall be for a
period of one (1) year and shall only be available to Tenant following the
initial Term of this Lease Agreement. The second and third Extended Terms shall
be for a period of five (5) years each, and shall be available to Tenant
following the first Extended Term. If, at the conclusion of the initial Term,
Tenant elects to waive Tenant’s right to the first Extended Term of one (1)
year, Tenant shall have the option to transition directly into the second
Extended Term of five (years). Each of the Extended Terms shall be subject to
the following terms, conditions and provisions:

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Exhibit 10.1

b.
The terms of Section 49 B of the Lease Agreement shall continue to apply to the
Renewal Options, except that the Annual Base Rent for the first Extended Term
shall be $10.00 per square foot.

10.    Balance of Terms. Except as set forth in this Amendment, the terms and
conditions of the Lease are hereby ratified and affirmed, and remain unchanged
and in full force and effect.

11.    Counterparts. This Amendment may be executed in counterparts, each of
which when taken together shall be deemed an original, but all of which shall be
deemed for all purposes one and the same instrument. Counterpart signatures may
be transmitted by facsimile and such fax signatures will be of full force and
effect as if such signatures were originals.

IN WITNESS WHEREOF, the parties have executed this Amendment as of the day and
year set forth above.

TENANT:            CARDIOVASCULULAR SYTEMS, INC.
                        

By:     /s/ John Hastings
Name:    John Hastings
Title:    VP Manufacturing & Operations

LANDLORD:            PEARLAND ECONOMIC DEVELOPMENT CORPORATION
                        

By:     /s/ Matt Buchanan
Name:    Matt Buchanan
Title:    President

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Exhibit 10.1

EXHIBIT A

Leased Premises

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Exhibit 10.1

EXHIBIT B

Parking Improvements

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Exhibit 10.1

EXHIBIT C

List of Building Repairs

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Exhibit 10.1

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Exhibit 10.1

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