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EXHIBIT 10-1

 
AGREEMENT AND PLAN OF MERGER
 
This Agreement and Plan of Merger (the "Agreement") is made as of this 17th day
of December 2015 by and among (i) Cantabio Pharmaceuticals Inc., a Delaware
corporation (the "Company"), (ii) Cantabio Acquisition Inc., a Delaware
corporation ("Merger Sub"), (iii) Gardedam Therapeutics, Inc., a
Delaware corporation ("Gardedam"), (iv) Dr. Gergely Toth, (v) Dr. Thomas Roger
Sawyer and (vi) Simon Peace (each a “Party” and together the “Parties”).
 
WHEREAS, the Company is authorized to issue 250,000,000 shares of its common
stock, par value $0.001 per share ("Authorized Common Stock"), of which
27,250,000 shares ("Issued Common Shares") are issued and outstanding as of the
date hereof and no shares of preferred stock exist, as of the date hereof; and
 
WHEREAS, Merger Sub is a wholly owned subsidiary of the Company and is
authorized to issue 1,000,000 shares of common stock, par value $0.001 per share
(the "Merger Sub Shares"), all of which are issued and outstanding and owned by
the Company as of the date hereof; and
 
WHEREAS, the respective Boards of Directors of the Company, Merger Sub and
Gardedam (the "Constituent Corporations") deem it advisable and in the best
interests of the Constituent Corporations, and their respective stockholders,
that Merger Sub be merged with and into the Gardedam (the "Merger") and the
Merger be effected pursuant to the Delaware General Corporation Law (the
"DGCL");
 
WHEREAS, as consideration for the Merger, (i) the Company will issue the
Gardedam shareholders approximately 15,500,000 shares of the Company’s common
stock, (ii) Dr. Toth will return 13,500,000 shares of the Company’s common stock
to treasury, (iii) Dr. Sawyer will return 1,000,000 shares of the Company’s
common stock to treasury (iv) Mr. Peace will return 1,000,000 shares of the
Company’s common stock to treasury; and
 
WHEREAS, it is intended that the Merger each be treated as a tax free
reorganization under Section 368(a) of the Internal Revenue Code of 1986, as
amended (the "Code"); and
 
NOW, THEREFORE, in consideration of the premises, covenants and conditions
hereof, the parties hereto do mutually agree as follows:
 
 
 

 

 
EXHIBIT 10.1, 1

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ARTICLE I
 
The Merger
 
SECTION 1.1                                The Merger. On the basis of the
representations, warranties, covenants and agreements set forth in this
Agreement and subject to the satisfaction or waiver of the conditions set forth
in this Agreement, at the Effective Time (as defined below) and in accordance
with the applicable provisions of the DGCL:

(a)           Merger Sub shall merger with and into Gardedam. Upon completion of
the Merger, the Gardedam shall be the surviving entity and the separate
corporate existence of Merger Sub shall thereupon cease. Gardedam, as the
surviving corporation in the Merger and a wholly-owned subsidiary of the Company
shall continue its existence under the name “Gardedam Therapeutics, Inc." and
shall continue to be governed by the DGCL. As consideration for the Merger, (i)
the shareholders of Gardedam relinquish all ownership of shares of capital stock
Gardedam to the Company in exchange for the issuance of approximately 15,500,000
common shares by the Company (the “Merger Common Stock”) and such Merger Common
Stock shall be issued to the Gardedam shareholders on a pro rata basis as to
their ownership of Gardedam, (ii) Dr. Gergely Toth Agrees to return to the
Company’s treasury 13,500,000 shares of the Company’s Common Stock, (iii) Dr.
Thomas Roger Sawyer agrees to return 1,000,000 shares of the Company’s Common
Stock to treasury and (iv) Simon Peace agrees to return 1,000,000 shares of the
Company’s Common Stock to treasury.
 
(b)           The Articles of Incorporation and By-laws of Gardedam, as in
effect immediately prior to the Effective Time, shall thereafter be the articles
of incorporation and by-laws of the surviving corporation in the Merger until
duly amended or repealed.
 
(c)           The members of the Board of Directors of Gardedam immediately
prior to the Effective Time shall thereafter be confirmed as members of the
Board of Directors of Gardedam as the surviving corporation in the Merger until
the earlier of their resignation or removal or until their respective successors
are duly elected or appointed and qualified in the manner provided in the
articles of incorporation and by-laws of the surviving corporation in the
Merger, or as otherwise provided by law.
 
(d)           The officers of Gardedam immediately prior to the Effective Time
shall be confirmed as the initial officers of Gardedam as the surviving
corporation in the Merger until the earlier of their resignation or removal or
until their respective successors are duly elected or appointed and qualified.
 
SECTION 1.2                                Closing. The closing of the
transactions contemplated by this Agreement (the "Closing") will take place
commencing at 9:00 Eastern time on the next business day after all the
conditions set forth in this Agreement have been satisfied or waived, or such
later date as agreed upon by the parties hereto (the "Closing Date").
 
    SECTION 1.3                          Filing of Certificate of Merger.
Subject to the provisions of this Agreement, as soon as practicable on the
Closing Date, Merger Sub and Gardedam shall cause Certificate of Merger
substantially in the form of Exhibit A attached hereto (the "Certificate of
Merger") or other appropriate documents, duly executed in accordance with the
relevant provisions of the DGCL and to be filed and recorded as required by the
DGCL and will take any other further actions in connection therewith as may be
required by the DGCL to make the Merger effective. The Merger shall become
effective at the later of the time the Certificate of Merger is duly filed or at
the effective time set forth in the Certificate of Merger (the "Effective
Time").
 

 
EXHIBIT 10.1, 2

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       SECTION 1.4                             Certain Effects of the Merger.
 
(a)           At the Effective Time, Merger Sub shall be merged with and into
Gardedam and the separate existence of Merger Sub shall cease. Gardedam, as the
surviving corporation in the Merger, shall thereupon and thereafter possess all
the rights, privileges, powers and franchises, of a public or of a private
nature, and be subject to all restrictions, liabilities and duties of each of
Gardedam and Merger Sub and shall continue its existence as a Mexican
corporation.
 
(b)           The parties to this Agreement intend that the Merger shall
constitute a tax free "reorganization". Each party to this Agreement hereby
agrees to file all tax returns, reports, or other documents, and to act in all
other respects, in a manner consistent therewith.
 
SECTION 1.5                           Effect of Merger on Capital Stock.
 
(a)           Cancellation of Gardedam Treasury Stock. At the Effective Time, by
virtue of the Merger and without any action on the part of the holders of
capital stock of Gardedam or of Merger Sub, each share of Gardedam Common Stock
issued and held in the treasury of Gardedam immediately prior to the Effective
Time shall cease to be outstanding, shall be canceled and retired without any
conversion thereof and without payment of any consideration therefor and shall
cease to exist.
 
(b)           Conversion of Gardedam Common Stock.
 
(i)           At the Effective Time, by virtue of the Merger and without any
action on the part of the holders of capital stock of Gardedam or of Merger Sub,
each share of Gardedam Common Stock issued and outstanding immediately prior to
the Effective Time (other than the shares of Gardedam Common Stock being
canceled pursuant to Section 1.5(a)), shall be converted into the right to
receive, 14.824 shares of Merger Common Stock (the "Merger Ratio") for each
share of Gardedam Common Stock without the need to surrender the certificate
representing the Gardedam Common Stock.  Any fractional share of Merger Common
Stock that would otherwise be issued pursuant to this Agreement shall be rounded
up to the nearest whole share of common stock of the Company.
 
(ii)           Each share of Gardedam Common Stock so converted at the Effective
Time shall be immediately canceled and retired without need for surrender to the
Company and shall cease to exist, and each certificate which theretofore
represented shares so converted and canceled shall thereafter cease to have any
rights with respect to such shares except the right to receive the Merger Common
Stock.
 
(c)           Merger Sub Shares. At the Effective Time, by virtue of the Merger
and without any action on the part of the holder thereof, each Merger Sub Share
issued and outstanding immediately prior to the Effective Time shall be
converted into and become an issued and outstanding share of common stock of the
surviving corporation in the Merger so that the Company will be the sole
shareholder of Gardedam.
 
(d)           Securities Act Exemption. The Merger Common Stock to be issued in
the Merger is intended to be exempt from the registration requirements of the
Securities Act of 1933, as amended (the "Securities Act"), pursuant to
Section 4(2) of the Securities Act and/or Regulation S thereunder and from
applicable state securities laws. The Company will use reasonable efforts to
facilitate each Gardedam stockholder taking all reasonable actions and executing
all necessary documents to qualify the issuance of Merger Common Stock for such
exemptions.
 

 
EXHIBIT 10.1, 3

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SECTION 1.6                       Delivery of New Certificates. Promptly after
the Effective Time, the Company shall send, by overnight courier, to each record
holder of certificates formerly representing all of such holder’s shares of
Gardedam Common Stock (the "Old Certificates"), at the address set forth on
books of Gardedam, (i) a notice of the effectiveness of the Merger and (ii) a
Letter of Transmittal.
 
SECTION 1.7                       No Further Ownership Rights in Gardedam Common
Stock. All consideration paid upon the conversion of Gardedam Common Stock shall
be deemed to have been paid in full satisfaction of all rights pertaining to the
shares of Gardedam Common Stock. At the Effective Time, the stock transfer books
of Gardedam shall be closed, and there shall be no further registration of
transfers on the stock transfer books of the surviving corporation in the Merger
of the shares of Gardedam Common Stock that were outstanding immediately prior
to the Effective Time. If, after the Effective Time, certificates representing
common stock of Gardedam are presented to the Company for any reason, they shall
not be recognized as valid and outstanding.
 
ARTICLE II
 
Representations and Warranties of Gardedam
 
Gardedam represents and warrants to each Party as follows:
 
SECTION 2.1                        Organization; Standing and Power. Gardedam is
a corporation duly incorporated, validly existing and in good standing under the
laws of Delaware and has all requisite corporate power and authority required to
own, lease and operate its properties and to carry on its business as currently
being conducted. Copies of the Articles of Incorporation and By-laws, corporate
minute books, stock certificate books and stock transfer books of Gardedam have
heretofore been delivered to the Company and are true, correct and complete.
Gardedam is not required to be qualified or licensed as a foreign corporation in
any other jurisdiction to conduct its business as currently conducted.
 
  SECTION 2.2                           Authorization.
 
(a)           Gardedam has all requisite corporate power and authority to
execute and deliver this Agreement and, subject to the approval by the
stockholders of Gardedam whose consent is required in accordance with the laws
of Delaware, to consummate the transactions contemplated by this Agreement.
 

 
EXHIBIT 10.1, 4

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(b)           Except for the consent and approval of the stockholders of
Gardedam, the execution, delivery and performance of the Agreement by Gardedam
and the consummation by Gardedam of the transactions contemplated by the
Agreement will not require on the part of Gardedam any permit, approval, order
or authorization of, or filing or registration with, or allowance by, or consent
of or notification to any federal, state or local government or any court,
administrative or regulatory agency or commission or other governmental agency
or authority, domestic or foreign (a "Governmental Authority") or any
individual, partnership, joint venture, corporation, limited liability company,
trust, unincorporated organization or other entity (including a Governmental
Authority) (a "Person").
 
SECTION 2.3                        Binding Agreement. This Agreement has been
duly executed and delivered by Gardedam , and assuming the due execution and
delivery of this Agreement by the Company, it constitutes the valid and binding
obligation of Gardedam, enforceable against it in accordance with its terms,
except to the extent that its enforceability may be limited by bankruptcy,
insolvency, reorganization, fraudulent conveyance, moratorium, receivership and
other similar laws affecting the enforcement of creditors' rights in general and
general principles of equity (regardless of whether such enforceability is
considered in a proceeding in equity or at law).
 
SECTION 2.4                        No Conflicts. The execution, delivery and
performance of the Agreement by Gardedam and the consummation by Gardedam of the
transactions contemplated by the Agreement will not, with or without the giving
of notice or lapse of time, or both, violate, conflict with, result in a breach
of, constitute a default under or accelerate the performance required by any of
the terms, conditions or provisions of (i) the Articles of Incorporation or
By-laws of Gardedam or (ii) except for such violations, conflicts, breaches,
defaults or accelerations that, individually or in the aggregate, have a
material adverse effect on the business of Gardedam, any contract, covenant,
agreement or understanding, or any statute, rule, regulation, order, decree,
ruling, judgment, arbitration award, law, ordinance or stipulation to which
Gardedam is a party or to which it or any of its properties or assets is
subject, or result in the creation of any liens, pledges, security interests,
charges, equities, options, proxies, voting restrictions, rights of first
refusal, encumbrances, restrictions (other than restrictions arising under
applicable securities laws) and claims of every kind and character
("Encumbrances") on any of its properties or assets.
 
SECTION 2.5                        Broker's or Finder's Fees. No agent, broker,
firm or other Person acting on behalf of Gardedam is, or will be, entitled to
any investment banking, commission, broker's or finder's fees from any of the
parties hereto, or from any Person controlling, controlled by or under common
control with any of the parties hereto, in connection with any of the
transactions contemplated by this Agreement.
 
SECTION 2.6                        Capitalization. The outstanding
capitalization of Gardedam is set forth on Schedule A annexed hereto. There are
issued and outstanding only the Issued Common Shares, all of which are duly
authorized and validly issued. No securities of Gardedam are entitled to
preemptive or similar rights and no Person has any right of first refusal, right
of participation, or any similar right to participate in the transactions
contemplated hereby. There are no outstanding options, warrants or other rights
to acquire capital stock of Gardedam, and there are no options, warrants, calls,
rights, commitments agreements, understandings or arrangements to which Gardedam
is a party or by which Gardedam is or may become bound to issue additional
shares of capital stock of Gardedam, or securities or rights convertible or
exchangeable into shares of capital stock of Gardedam prior to the Effective
Time.
 

 
EXHIBIT 10.1, 5

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SECTION 2.7                        Subsidiaries. Gardedam does not have any
subsidiaries, nor does it own any direct or indirect interest in any other
business entity.
 
SECTION 2.8                        Financial Statements. Gardedam has furnished
the Company with a true and complete copy of (i) the audited balance sheets of
Gardedam as of December 31, 2014, and the related audited statements of income
and statements of cash flow of Gardedam for the interim period ended September
30, 2015 (the "Financial Statements"). The Financial Statements fairly present
in all material respects the financial position, results of operations and other
information purported to be shown thereon of Gardedam, at the dates and for the
respective periods to which they apply, subject, in the case of the Financial
Statements, to normal, immaterial year-end audit adjustments. All such Financial
Statements have been reviewed by PLS CPA and are accompanied by their report and
were prepared in conformity with United States generally accepted accounting
principles ("GAAP") consistently applied throughout the periods involved, and
have been adjusted for all normal and recurring accruals.
 
SECTION 2.9                        No Adverse Changes. There has not been any
material adverse change in the financial condition of Gardedam from that set
forth in the Financial Statements except for (i) transactions in the ordinary
course of business since September 30, 2015 and (ii) transactions, including but
not limited to the incurring of expenses and liabilities, relating to this
Agreement.
 
          SECTION 2.10                         Liabilities; Claims. There are no
liabilities (including, but not limited to, tax liabilities) or claims against
Gardedam (whether such liabilities or claims are contingent or absolute, direct
or indirect, and matured or unmatured) not appearing in the Financial
Statements, other than (i) liabilities incurred in the ordinary course of
business since September 30, 2015, (ii) taxes accrued on earnings since
September 30, 2015 which are not yet due or payable or (iii) other liabilities
which do not exceed $5,000 in the aggregate.
 
          SECTION 2.11                         Material Contracts. All written
agreements, contracts, letters of intent, arrangements, understandings and
commitments to which Gardedam is a party and which are material to Gardedam
(collectively, " Gardedam Contracts") are in good standing, valid and effective
in accordance with their respective terms, and neither Gardedam nor any other
party to a contract has violated any provision of, or committed or failed to
perform any act which, with or without notice, lapse of time or both, would
constitute a default under the provisions of, any such contract. Gardedam is not
a party to or bound by any contract which would prohibit or materially delay the
consummation of transactions contemplated by this Agreement.
 
          SECTION 2.12                           Tax Matters.
 
(a)           All federal, state, county, local and foreign income, excise,
property and other tax returns required to be filed by Gardedam have been timely
filed and all such duly filed tax returns are true and correct in all material
respects. All required taxes, fees or assessments have been paid or an adequate
reserve therefore has been established (in accordance with GAAP) in the
Financial Statements. The federal income tax returns and state and foreign
income tax returns of Gardedam have not been audited by any taxing authority and
Gardedam has not received any notice of deficiency or assessment from any taxing
authority with respect to liability for taxes which has not been fully paid or
finally settled. No state, local, foreign or other taxing authority has proposed
in writing any additional taxes, interest or penalties with respect to Gardedam
or any of its operations or businesses. There are no pending, or to the
knowledge of Gardedam, threatened, tax claims or assessments, and there are no
pending, or to the knowledge of Gardedam, threatened, tax examinations by any
taxing authorities. Gardedam has not given any waivers of rights (which are
currently in effect) under applicable statutes of limitations with respect to
taxes of Gardedam for any taxable period. There are no liens for taxes upon the
assets of Gardedam except for statutory liens for current taxes not yet due and
payable or which may thereafter be paid without penalty or are being contested
in good faith. Gardedam has not filed a request for changes in accounting
methods within the last three (3) years which change would affect the accounting
for tax purposes, directly or indirectly, of its business.
 

 
EXHIBIT 10.1, 6

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(b)            Gardedam does not have any liability for taxes of any person as a
result of being a member of an affiliated, consolidated, combined or unitary
group, nor is it bound by any obligation under any tax sharing agreement, tax
indemnification agreement or similar contract or arrangement.
 
SECTION 2.13                             Legal Proceedings. There are no legal,
administrative, arbitral or other proceedings, claims, suits, actions or
governmental investigations of any nature pending, or to Gardedam's knowledge,
threatened, directly or indirectly involving Gardedam or its officers,
directors, employees or affiliates, which would reasonably be expected to have a
material adverse effect on the business of Gardedam or challenging the validity
of the transactions contemplated by this Agreement. Gardedam is not a party to
any order, judgment, injunction, rule or decree of any Governmental Authority or
arbitrator which would reasonably be expected to have a material adverse effect
on the business of Gardedam.
 
SECTION 2.14                             Permits; Compliance with Laws. Gardedam
has all governmental licenses, authorizations, permits, consents and approvals
("Permits") required to own, lease and operate its properties and to carry on
its business as currently conducted. Gardedam: (i) is not in default under or in
violation of (and no event has occurred that has not been waived that, with
notice or lapse of time or both, would result in a default by Gardedam under),
nor has Gardedam received notice of a claim that it is in default under or that
it is in violation of, any indenture, mortgage, deed of trust or other
agreement, instrument or contract to which Gardedam is a party or by which it or
any of its assets or properties are bound (whether or not such default or
violation has been waived), (ii) is not in violation of any order of any court,
arbitrator or Governmental Authority, (iii) is not and has not been in violation
of any law, order, rule, regulation, writ, injunction, judgment or decree of any
Governmental Authority having jurisdiction over Gardedam or any of its business
or properties, including federal and state securities laws and regulations and
(iv) is not in violation of any of its Permits, except where the failure to so
comply did not have and would not reasonably be expected to have a material
adverse effect on the business of Gardedam.
 
SECTION 2.15                             Intellectual Property. Gardedam owns or
possesses adequate rights or licenses to use all trademarks, trade names,
service marks, service mark registrations, service names, patents, patent
rights, copyrights, original works, inventions, licenses, approvals,
governmental authorizations, trade secrets and other intellectual property
rights and all applications and registrations therefor (“Intellectual Property
Rights”) necessary to conduct their respective businesses as now
conducted.  Gardedam has no knowledge of any infringement by Gardedam of
intellectual property rights of others.  Gardedam has no knowledge of any claim,
action or proceeding being made or brought it or being threatened, against
Gardedam regarding their Intellectual Property Rights.  Gardedam has no
knowledge of any facts or circumstances which might give rise to any of the
foregoing infringements or claims, actions or proceedings.  Gardedam has taken
reasonable security measures to protect the secrecy, confidentiality and value
of all of its Intellectual Property Rights.
 
  SECTION 2.16                           Related Party Contracts None of the
officers, directors, or affiliates of Gardedam is presently a party to any
transaction with Gardedam (other than for services as employees, officers and
directors), including any loans, leases, agreements, arrangements or
understandings outstanding between Gardedam and any of its officers, directors,
or affiliates or any person related to or affiliated with any such officers or
directors.
 

 
EXHIBIT 10.1, 7

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SECTION 2.17                           Benefit Plans. Gardedam does not have any
pension, retirement, savings, profit sharing, stock-based, incentive
compensation or other similar employee benefit plan.
 
ARTICLE III
 
Representations and Warranties Regarding Merger Sub
 
The Company and Merger Sub each jointly and severally represents and warrants to
Gardedam as follows with respect to Merger Sub:
 
SECTION 3.1                           Organization; Capitalization. Merger Sub
is a duly organized and validly existing corporation in good standing under the
laws of Delaware, authorized to issue only the Merger Sub Shares.  There are no
issued or outstanding options or warrants to purchase Merger Sub Shares or any
issued or outstanding securities of any nature convertible into Merger Sub
Shares, or any agreements or understandings to issue any Merger Sub Shares,
options or warrants.
 
SECTION 3.2                           Authorization.
 
(a)           Merger Sub has all requisite corporate power and authority to
execute and deliver this Agreement and to consummate the transactions
contemplated by this Agreement.
 
(b)           Except for the filing of the Articles of Merger and the
Certificate of Merger, the execution, delivery and performance of the Agreement
by Merger Sub and the consummation by Merger Sub of the transactions
contemplated by the Agreement will not require on the part of Merger Sub any
permit, approval, order or authorization of, or filing or registration with, or
allowance by, or consent of or notification to any Person.
 
        SECTION 3.3                         Binding Agreement. This Agreement
has been duly executed and delivered by Merger Sub, and assuming the due
execution and delivery of this Agreement by the Company and Merger Sub,
constitutes the valid and binding obligation of Merger Sub, enforceable against
it in accordance with its terms, except to the extent that its enforceability
may be limited by bankruptcy, insolvency, reorganization, fraudulent conveyance,
moratorium, receivership and other similar laws affecting the enforcement of
creditors' rights in general and general principles of equity (regardless of
whether such enforceability is considered in a proceeding in equity or at law).
 
        SECTION 3.4                         No Conflicts. The execution,
delivery and performance of the Agreement by Merger Sub and the consummation by
Merger Sub of the transactions contemplated by the Agreement will not, with or
without the giving of notice or lapse of time, or both, violate, conflict with,
result in a breach of, constitute a default under or accelerate the performance
required by any of the terms, conditions or provisions of (i) the Certificate of
Incorporation or By-laws of Merger Sub or (ii) any statute, rule, regulation,
order, decree, ruling, judgment, arbitration award, law, ordinance or
stipulation to which Merger Sub or any of its properties or assets is subject,
or result in the creation of any Encumbrances on any of its properties or
assets.
 

 
EXHIBIT 10.1, 8

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SECTION 3.5                         Broker's or Finder's Fees. No agent, broker,
firm or other Person acting on behalf of Merger Sub is, or will be, entitled to
any investment banking, commission, broker's or finder's fees from any of the
parties hereto, or from any Person controlling, controlled by or under common
control with any of the parties hereto, in connection with any of the
transactions contemplated by this Agreement.
 
SECTION 3.6                         No Business Activity; Financial Condition.
Merger Sub has been organized solely for the purpose of consummating the Merger
and, since its inception, has had no business activity of any nature other than
those related to its organization or as contemplated by this Agreement. Merger
Sub has no contracts or commitments to which it is a party, except for this
Agreement and other documents and instruments contemplated hereby in connection
with the Merger. Except for (i) the incurring of expenses of its organization,
(ii) the issuance of the Merger Sub Shares to the Company, (iii) the incurring
of expenses relating to this Agreement and the consummation of the transactions
contemplated by this Agreement and (iv) the consummation of the Merger, Merger
Sub has had no financial or other transactions of any nature whatsoever. As of
the date hereof, Merger Sub has no subsidiaries.
 
ARTICLE IV
 
 
Representations and Warranties Regarding the Company
 
The Company hereby represents and warrants to Gardedam as follows, except to the
extent set forth on the corresponding sections of the schedule of exceptions
attached hereto and made a part hereof:
 
SECTION 4.1                           Organization; Standing and Power. The
Company is a corporation duly incorporated, validly existing and in good
standing under the laws of the State of Delaware and has all requisite corporate
power and authority required to own, lease and operate its properties and to
carry on its business as currently being conducted. Copies of the Certificate of
Incorporation and By-laws, corporate minute books, stock certificate books and
stock transfer books of the Company that have heretofore been delivered to
Gardedam are true, correct and complete. The Company is not required to be
qualified or licensed as a foreign corporation in any other jurisdiction to
conduct its business as currently conducted.
 
SECTION 4.2                           Authorization.
 
(a)           The Company has all requisite corporate power and authority to
execute and deliver this Agreement and, subject to the approval by the
stockholders of the Company whose consent is required in accordance with the
laws of the State of Delaware to consummate the Reincorporation and the
transactions related thereto, and to consummate the transactions contemplated by
this Agreement.
 
(b)           The execution, delivery and performance of the Agreement by the
Company and the consummation by the Company of the transactions contemplated by
the Agreement will not require on the part of the Company any permit, approval,
order or authorization of, or filing or registration with, or allowance by, or
consent of or notification to any Person.
 

 
EXHIBIT 10.1, 9

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SECTION 4.3                           Binding Agreement. This Agreement has been
duly executed and delivered by the Company, and constitutes the valid and
binding obligation of the Company, enforceable against it in accordance with its
terms, except to the extent that its enforceability may be limited by
bankruptcy, insolvency, reorganization, fraudulent conveyance, moratorium,
receivership and other similar laws affecting the enforcement of creditors'
rights in general and general principles of equity (regardless of whether such
enforceability is considered in a proceeding in equity or at law).
 
SECTION 4.4                           No Conflicts. The execution, delivery and
performance of the Agreement by the Company and the consummation by the Company
of the transactions contemplated by this Agreement will not, with or without the
giving of notice or lapse of time, or both, violate, conflict with, result in a
breach of, constitute a default under or accelerate the performance required by
any of the terms, conditions or provisions of (i) the Certificate of
Incorporation or By-laws of the Company or (ii) except for such violations,
conflicts, breaches, defaults or accelerations that, individually or in the
aggregate, have a material adverse effect on the business of the Company, any
contract, covenant, agreement or understanding, or any statute, rule,
regulation, order, decree, ruling, judgment, arbitration award, law, ordinance
or stipulation to which the Company is a party or to which it or any of its
properties or assets is subject, or result in the creation of any Encumbrances
on any of its properties or assets.
 
SECTION 4.5                           Broker's or Finder's Fees. No agent,
broker, firm or other Person acting on behalf of the Company is, or will be,
entitled to any investment banking, commission, broker's or finder's fees from
any of the parties hereto, or from any Person controlling, controlled by or
under common control with any of the parties hereto, in connection with any of
the transactions contemplated by this Agreement.
 
        SECTION 4.6                         Capitalization.
 
(a)           The authorized capital stock of the Company consists of
250,000,000 shares of Common Stock.  The Company declares that all such stock,
as referred below, is the total amount of stock of the Company and there is no
preferred stock or other different from such as above mentioned. All of the
issued and outstanding shares of capital stock of the Company have been duly
authorized and validly issued and are fully paid and non assessable. All of the
issued and outstanding shares of capital stock of the Company have been offered,
issued and sold by the Company in compliance with all applicable federal and
state securities laws. No securities of the Company are entitled to preemptive
or similar rights, and no Person has any right of first refusal, preemptive
right, right of participation, or any similar right to participate in the
transactions contemplated hereby. There are no outstanding options, warrants or
other rights to acquire capital stock of the Company and there are no
securities, options, warrants, calls, rights, commitments, agreements,
understandings or arrangements to which the Company is a party or by which the
Company is or may become bound to issue additional shares of capital stock of
the Company, or securities or rights convertible or exchangeable into shares of
capital stock of the Company.
 
(b)           There are no outstanding obligations, contingent or otherwise, of
the Company to redeem, purchase or otherwise acquire any capital stock or other
securities of the Company.
 

 
EXHIBIT 10.1, 10

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(c)           There are no stockholder agreements, voting trusts or other
agreements or understandings to which the Company is a party or by which the
Company is bound relating to the voting of any shares of the capital stock of
the Company.
 
SECTION 4.7                           Subsidiaries. Other than the Merger Sub,
the Company does not have any subsidiaries, nor does it own any direct or
indirect interest in any other business entity.
 
SECTION 4.8                           Investment Company/Investment Adviser. The
business of the Company does not require it to be registered as an investment
company, as such term is defined under the Investment Company Act of 1940, as
amended, nor does it require the Company to be registered as an investment
adviser, as such term is defined under the Investment Advisers Act of 1940, as
amended, or under applicable Delaware State laws.
 
SECTION 4.9                           Assets; Liens. The Company has not
acquired any assets, including, without limitation, goodwill, assets, real
property, tangible personal property, intangible personal property, rights and
benefits under contracts and cash. No Encumbrances exist on any of the Company's
assets.
 
SECTION 4.10                           Liabilities; Claims. Except as set forth
in all registration statements, prospectuses, reports, schedules, forms,
statements and other documents required to be filed by it with the Securities
and Exchange Commission (the "SEC") under the Securities Act and the Securities
Exchange Act of 1934, as amended (the "Exchange Act"), including pursuant to
Section 13(a) or 15(d) thereof, (the foregoing materials being collectively
referred to herein as the "SEC Reports"), there are no liabilities (including,
but not limited to, tax liabilities) or claims against the Company (whether such
liabilities or claims are contingent or absolute, direct or indirect, and
matured or unmatured), and there is no existing condition, situation or set of
circumstances which could reasonably be expected to result in such a liability
or claim.
 
SECTION 4.11                           Legal Proceedings. There are no legal,
administrative, arbitral or other proceedings, claims, suits, actions or
governmental investigations of any nature pending, or to the Company's knowledge
threatened, directly or indirectly involving the Company or its officers,
directors or affiliates, including, but not limited to any stockholder claims or
derivative actions, or challenging the validity or propriety of the transactions
contemplated by this Agreement. The Company is not subject to any order,
judgment, injunction, rule or decree of any Governmental Authority or
arbitrator.
 
SECTION 4.12                           Insurance. The Company has no casualty
and liability policies and other insurance policies.
 
SECTION 4.13                           Intellectual Property. The Company has no
patents, patent applications, trademarks, trademark registrations or
applications therefore, service marks, service mark registrations or
applications therefore, trade names, copyrights, copyright registrations or
applications therefore or any other proprietary intellectual property and other
rights relating to the foregoing. The Company has no knowledge of any
infringements by the Company of any third party's intellectual property.
 

 
EXHIBIT 10.1, 11

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SECTION 4.14                           Permits; Compliance with Laws. The
Company has all Permits required to own, lease and operate its properties and to
carry on its business as currently conducted. The Company: (i) is not in default
under or in violation of (and no event has occurred that has not been waived
that, with notice or lapse of time or both, would result in a default by the
Company under), nor has the Company received notice of a claim that it is in
default under or that it is in violation of, any indenture, mortgage, deed of
trust or other agreement, instrument or contract to which the Company is a party
or by which it or any of its assets or properties are bound (whether or not such
default or violation has been waived), (ii) is not in violation of any order of
any court, arbitrator or governmental body, (iii) is not and has not been in
violation of any law, order, rule, regulation, writ, injunction, judgment or
decree of any Governmental Authority having jurisdiction over the Company or any
of its business or properties, including federal and state securities laws and
regulations and (iv) is not in violation of any of its Permits.
 
SECTION 4.15                           Related Party Contracts. Except as set
forth in the SEC Reports, none of the officers, directors, or affiliates of the
Company is presently a party to any transaction with the Company (other than for
services as employees, officers and directors), including any loans, leases,
agreements, arrangements or understandings outstanding between the Company and
any of its officers, directors, or affiliates or any person related to or
affiliated with any such officers or directors.
 
SECTION 4.16                           Employee Matters; Benefit Plans. The
Company has no employees and there are no labor disputes, grievances or requests
for arbitration. Except for the Stock Award to Steven A Sanders, the Company has
no pension, retirement, savings, profit sharing, stock-based, incentive
compensation or other similar employee benefit plan.
 
ARTICLE V
 
Representations and Warranties of Dr. Toth, Dr. Sawyer and Mr. Peace.
 
SECTION 5.1                                Dr. Toth represents to Gardedam that
(i) he is the sole owner of 13,500,000 of shares of common stock of the Company
(the “Toth Shares”), (ii) that no liens, judgments or other instruments exist
over the Toth Shares or Dr. Toth that would prevent their return to treasury,
(iii) he has executed all documents that are required by the Company’s transfer
agent to return the Toth Shares to treasury and delivered the same to the
Company’s counsel with instructions that such documents be delivered to the
Company’s transfer agent upon the occurrence of the Merger.
 
SECTION 5.2                                Dr. Sawyer represents to Gardedam
that (i) he is the sole owner of 1,000,000 of shares of common stock of the
Company (the “Sawyer Shares”), (ii) that no liens, judgments or other
instruments exist over the Sawyer Shares or Dr. Sawyer that would prevent their
return to treasury, (iii) he has executed all documents that are required by the
Company’s transfer agent to return the Sawyer Shares to treasury and delivered
the same to the Company’s counsel with instructions that such documents be
delivered to the Company’s transfer agent upon the occurrence of the Merger.
 

 
EXHIBIT 10.1, 12

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SECTION 5.3                                Mr. Peace represents to Gardedam that
(i) he is the sole owner of 1,000,000 of shares of common stock of the Company
(the “Peace Shares”), (ii) that no liens, judgments or other instruments exist
over the Peace Shares or Mr. Peace that would prevent their return to treasury,
(iii) he has executed all documents that are required by the Company’s transfer
agent to return the Peace Shares to treasury and delivered the same to the
Company’s counsel with instructions that such documents be delivered to the
Company’s transfer agent upon the occurrence of the Merger.
 
ARTICLE VI
 
Non-Survival of Representations, Warranties and Agreements
 
SECTION 6.1                                None of the representations,
covenants and warranties contained in this Agreement (including, but not limited
to, all statements contained in any certificate or other instrument delivered by
or on behalf of the Company, Merger Sub, or Gardedam pursuant hereto or in
connection with the transactions contemplated hereby) shall survive the
Effective Time, except for the covenants and agreements that by their terms
apply or are to be performed in whole or in part after the Effective Time.
 
ARTICLE VII
 
Conditions of Obligations of Merger Sub and the Company
 
The obligation of Merger Sub and the Company to consummate the Merger and other
transactions contemplated hereby is subject to the satisfaction or waiver of the
following conditions prior to the Closing Date:
 
SECTION 7.1                           Compliance with Representations,
Warranties and Covenants. Each of the representations and warranties of Gardedam
set forth in this Agreement should be true and correct as the date hereof and as
the Closing Date as though made on and as of the Closing Date and Gardedam shall
be in compliance with its covenants contained herein in all material respects,
and Merger Sub and the Company each shall receive from Gardedam certificates to
such effect from an officer of Gardedam as of the Closing Date.
 
SECTION 7.2                           No Material Adverse Change. Except as
disclosed in this Agreement or in the Gardedam Schedule of Exceptions, no
material adverse change in the aggregate shall have occurred in the financial
condition, business, properties, assets, liabilities or results of operations of
Gardedam since the last SEC Report .
 
SECTION 7.3                           Filings and Approvals. All applicable
filings and regulatory approvals, as well as any other third party approvals,
required to be made or obtained by Gardedam shall have been made or obtained.
 
SECTION 7.4                           Stockholder Approvals. This Agreement and
the transactions contemplated hereby shall have been approved by appropriate
action of the stockholders of Gardedam and resolutions to that effect shall have
been delivered to the Company.
 

 
EXHIBIT 10.1, 13

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SECTION 7.5                           No Claims. No claim, suit, action or other
proceeding shall be pending or threatened in writing before or by any court or
Governmental Authority against Gardedam that could materially and adversely
affect the ability of Gardedam to consummate the transactions contemplated by
this Agreement.
 
SECTION 7.6                           No Injunctions, Restraints or Pending
Governmental Actions; Illegality. No applicable laws shall have been adopted,
promulgated or enforced by any Governmental Authority, and no temporary
restraining order, preliminary or permanent injunction or other order issued by
a court or other Governmental Authority of competent jurisdiction (an
"Injunction") shall be in effect, having the effect of making the Merger illegal
or otherwise prohibiting consummation of the Merger. No proceeding initiated by
any Governmental Authority seeking, and which is reasonably likely to result in
the granting of, an Injunction shall be pending.
 
SECTION 7.7                           Return to Treasury. All documents required
by the Company’s transfer agent to return to treasury the Toth Shares, the
Sawyer Share and the Peace Shares have been delivered to the Company’s counsel
with irrevocable instructions to deliver the same to the Company’s transfer
agent upon occurrence of the Merger.
 
ARTICLE VIII
 
Conditions of Obligations of Gardedam
 
The obligations of Gardedam to consummate the Merger are subject to the
following conditions prior to the Closing Date:
 
SECTION 8.1                          Compliance with Representations, Warranties
and Covenants. Each of the representations and warranties of Merger Sub and the
Company set forth in this Agreement (other than those representations and
warranties which are made as of a specified date herein) shall be true and
correct as of the date hereof and as of Closing Date as though made on and as of
the Closing Date and Merger Sub and the Company shall be in compliance with
their respective covenants contained herein in all material respects, and
Gardedam shall have received from each of Merger Sub and the Company a
certificate to such effect from an officer of Merger Sub and the Company, as the
case may be, as of the Closing Date.
 
SECTION 8.2                          No Material Transactions. Except as
disclosed in this Agreement or pursuant to the Reincorporation, no material
transactions shall have been entered into by Merger Sub or the Company, other
than transactions in the ordinary course of business, since the most recent SEC
Report, except as referred to in this Agreement or in connection herewith, with
the prior written consent of Gardedam.
 
SECTION 8.3                          No Material Adverse Change. Except as
disclosed in this Agreement or pursuant to the Reincorporation, no material
adverse change shall have occurred in the financial condition, business,
properties, assets, liabilities or results of operations of Merger Sub or the
Company since the most recent SEC Report.
 

 
EXHIBIT 10.1, 14

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SECTION 8.4                          No Claims. No claim, suit, action or other
proceeding shall be pending or threatened in writing before or by any court or
Governmental Authority against the Company or Merger Sub that could materially
and adversely affect the ability of the Company or Merger Sub to consummate the
transaction contemplated by this Agreement.
 
SECTION 8.5                          No Injunctions, Restraints or Pending
Governmental Actions; Illegality. No applicable laws shall have been adopted,
promulgated or enforced by any Governmental Authority, and no Injunction shall
be in effect, having the effect of making the Merger illegal or otherwise
prohibiting consummation of the Merger. No proceeding initiated by any
Governmental Authority seeking, and which is reasonably likely to result in the
granting of, an Injunction shall be pending.
 
SECTION 8.6                          Super 8-K Information. The Company will
have prepared and able to file a current report on Form 8-K reporting the merger
that is compliant with, and provides the information required under, Items 1.01,
3.02, 5.01, 5.06, 9.01 and any other applicable Item of Form 8-K (the “Super
8-K”) including the necessary financial information and Gardedam will have
signed off on the Super 8-K to be filed with 4 days of the Effective Date.
 
ARTICLE IX
Other Covenants
 
SECTION 9.1                           Public Announcements. No press release or
announcement concerning this Agreement or the transactions related hereto will
be issued by any party without the prior consent of the other parties, except as
such release or announcement may be required by law, in which case the party
required to make the release or announcement will, to the extent practicable,
allow the other party reasonable time to comment on such release or announcement
in advance of such issuance.
 
SECTION 9.2                           Further Instruments and Actions. Each
party shall deliver such further instruments and take such further action as may
be reasonably requested by any other party hereto in order to carry out the
intent and purposes of this Agreement.
 
        SECTION 9.3                         Issuance of Stock. Following the
Closing, the Company shall issue the Merger Common Stock to the Original
Gardedam Shareholders.
 
ARTICLE X
 
Termination or Abandonment
 
SECTION 10.1                             Termination or Abandonment. This
Agreement may be terminated and may be abandoned by mutual agreement or by
either the Company or Gardedam, by written notice to the other parties hereto,
at any time in the event of the failure of any condition in favor of such entity
as to which the consummation of the Acquisition is subject. In the event of
termination of this Agreement, the same shall become wholly void and of no
effect, and there shall be no further liability or obligation hereunder on the
part of any of the Constituent Corporations, their respective Boards of
Directors or any other party to this Agreement.
 

 
EXHIBIT 10.1, 15

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ARTICLE XI
 
Miscellaneous
 
SECTION 11.1                           Notices. All notices, requests and other
communications to any party hereunder shall be in writing and either delivered
personally, emailed or sent by certified or registered mail, postage prepaid,
 
If to the Company:

2225 East Bayshore Road #223
Palo Alto
CA 94303
USA

info@cantabio.com

If to Gardedam :

2443 Fillmore St #380-8102
San Francisco, CA 94115
USA

gtoth@gardedamtherapeutics.com

or such other address or email address as such party may hereafter specify for
the purpose by notice to the other parties hereto. All such notices, requests
and other communications shall be deemed received on the date delivered
personally or by overnight delivery service or emailed or, if mailed, five (5)
business days after the date of mailing.
 
SECTION 11.2                           Amendments; No Waivers.
 
(a)           Any provision of this Agreement with respect to transactions
contemplated hereby may be amended or waived if, but only if, such amendment or
waiver is in writing and is signed, in the case of an amendment, by the Company
and Gardedam; or in the case of a waiver, by the party against whom the waiver
is to be effective.
 
(b)           No failure or delay by any party in exercising any right, power or
privilege hereunder shall operate as a waiver thereof nor shall any single or
partial exercise thereof preclude any other or further exercise thereof or the
exercise of any other right, power or privilege. The rights and remedies herein
provided shall be cumulative and not exclusive of any rights or remedies
provided by law.
 
SECTION 11.3                           Fees and Expenses. Except as otherwise
provided in this Agreement, all costs and expenses incident to negotiation,
preparation and performance of this Agreement and the transactions contemplated
hereby shall be paid by the party incurring such costs and expenses, including,
without limitation, fees, expenses and disbursements of their respective
financial advisors, accountants and counsel.
 

 
EXHIBIT 10.1, 16

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SECTION 11.4                           Successors and Assigns. The provisions of
this Agreement shall be binding upon and inure to the benefit of the parties
hereto and their respective successors and assigns, but any such transfer or
assignment will not relieve the appropriate party of its obligations hereunder.
 
SECTION 11.5                           Governing Law. This Agreement shall be
governed by and construed in accordance with the laws of the State of Delaware,
without giving effect to the principles of conflicts of law thereof.
 
SECTION 11.6                           Jurisdiction. Any suit, action or
proceeding seeking to enforce any provision of, or based on any matter arising
out of or in connection with, this Agreement or the transactions contemplated
hereby may be brought in any federal or state court located in New York County,
New York, and each of the Parties hereto consents to the jurisdiction of such
courts (and of the appropriate appellate courts therefrom) in any such suit,
action or proceeding and irrevocably waives, to the fullest extent permitted by
law, any objection which it may now or hereafter have to the laying of the venue
of any such suit, action or proceeding in any such court or that any such suit,
action or proceeding which is brought in any such court has been brought in an
inconvenient forum. Process in any such suit, action or proceeding may be served
on any party anywhere in the world, whether within or without the jurisdiction
of any such court. Without limiting the foregoing, each party agrees that
service of process on such party as provided in Section 11.1 shall be deemed
effective service of process on such party. Each party hereto (including its
affiliates, agents, officers, directors and employees) irrevocably waives, to
the fullest extent permitted by applicable law, any and all right to trial by
jury in any legal proceeding arising out of or relating to this Agreement or the
transactions contemplated hereby.
 
SECTION 11.7                           Counterparts; Effectiveness. This
Agreement may be signed in any number of counterparts, each of which shall be an
original, with the same effect as if the signatures thereto and hereto were upon
the same instrument. This Agreement shall become effective when each party
hereto has received counterparts hereof signed by all of the other parties. No
provision of this Agreement is intended to confer upon any Person other than the
parties hereto any rights or remedies under this Agreement.
 
SECTION 11.8                           Entire Agreement. This Agreement and the
attached Exhibits and Schedules constitute the entire agreement between the
parties with respect to the subject matter of this Agreement and supersedes all
prior agreements and understandings, both oral and written, between the parties
with respect to the subject matter of this Agreement.
 
SECTION 11.9                           Consent. Whenever consent is required to
be given by any party to any other party hereunder in connection with any matter
contemplated hereby, such consent shall not be unreasonably withheld, delayed or
conditioned.
 
SECTION 11.10                           Captions. The captions are included for
convenience of reference only and shall be ignored in the construction or
interpretation of this Agreement.
 

 
EXHIBIT 10.1, 17

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SECTION 11.11                           Joint Drafting. This Agreement shall be
deemed to have been drafted jointly by the parties hereto, and no inference or
interpretation against any party shall be made solely by virtue of such party
allegedly having been the draftsperson of this Agreement.
 
SECTION 11.12                           Public Announcements. All parties hereto
agree that any public announcement, press release or other public disclosure of
the signing of this Agreement shall be made jointly and only after all parties
hereto have reviewed and approved the language and timing of such disclosure.
 
SECTION 11.13                           Severability. If any term, provision,
covenant or restriction of this Agreement is held by a court of competent
jurisdiction or other authority to be invalid, void or unenforceable, the
remainder of the terms, provisions, covenants and restrictions of this Agreement
shall remain in full force and effect and shall in no way be affected, impaired
or invalidated so long as the economic or legal substance of the transactions
contemplated hereby is not affected in any manner materially adverse to any
parties. Upon such a determination, the parties shall negotiate in good faith to
modify this Agreement so as to effect the original intent of the parties as
closely as possible in an acceptable manner in order that the transactions
contemplated hereby are consummated as originally contemplated to the fullest
extent possible.
 
SECTION 11.14                           Specific Performance. The parties hereto
agree that irreparable damage would occur in the event any provision of this
Agreement was not performed in accordance with the its terms and that the
parties shall be entitled to specific performance of the terms of this Agreement
in addition to any other remedy to which they are entitled at law or in equity.
 
[REMAINDER OF THE PAGE INTENTIONALLY LEFT BLANK]
 

 

 
EXHIBIT 10.1, 18

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IN WITNESS WHEREOF, the parties hereto have made and executed this Agreement as
of the day and year first above written.
 

 
CANTABIO PHARMACEUTICALS INC.
By: ________________________________
Name:
Title:
DR. GERGLEY TOTH
 
By: ________________________________
 
GARDEDAM THERAPEUTICS INC.
By: ________________________________
Name:
Title:
DR. THOMAS ROGER SAWYER
 
By: ________________________________
 
CANTABIO ACQUISITION INC.
By: ________________________________
Name:
Title:
SIMON PEACE
 
By: ________________________________
 

 

 

 
 

 
EXHIBIT 10.1, 19

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SCHEDULE A
 

 
EXHIBIT 10.1, 20

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Section 2.6 Capitalization – Gardedam Therapeutics [---].
 
Authorized Shares of Common Stock:
10,000,000
Authorized Shares of Preferred Stock:
0
Outstanding Shares of Common Stock:
1,000,000
Shares of Common Stock Issuable Upon Exercise of Outstanding Options/Warrants:
0
Fully-Diluted Common Shares Outstanding:
1,000,000

 
EXHIBIT 10.1, 21

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Exhibit A

STATE OF DELAWARE CERTIFICATE OF MERGER OF DOMESTIC CORPORATIONS

Pursuant to Title 8, Section 251(c) of the Delaware General Corporation Law, the
undersigned corporation executed the following Certificate of Merger:

FIRST: The name of the surviving corporation is Gardedam Therapeutics Inc. and
the name of the corporation being merged into this surviving corporation is
Cantabio Acquisition Inc.

SECOND: The Agreement of Merger has been approved, adopted, certified, executed
and acknowledged by each of the constituent corporations.

THIRD: The name of the surviving corporation is Gardedam Therapeutics Inc., a
Delaware corporation.

FOURTH: The Certificate of Incorporation of the surviving corporation shall be
its Certificate of Incorporation.

FIFTH: The merger is to become effective on the date hereof.

SIXTH: The Agreement of Merger is on file at [Gardedam address], the place of
business of the surviving corporation.

SEVENTH: A copy of the Agreement of Merger will be furnished by the surviving
corporation on request, without cost, to any stockholder of the constituent
corporations.

IN WITNESS WHEREOF, said surviving corporation has caused this certificate to be
signed by an authorized officer, the______________ day of ________________,A.D.,
________.

By:____________________________________ Authorized Officer
Name:____________________________________ Print or Type
Title:____________________________________

 
 
EXHIBIT 10.1, 22

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