Exhibit 10.26

FIRST AMENDMENT TO AMENDED AND RESTATED

EXECUTIVE EMPLOYMENT AGREEMENT

This First Amendment (the “Amendment”) to the Amended and Restated Executive
Employment Agreement (the “Agreement”) dated September 5, 2007, by and between
CryoCor, Inc., a Delaware corporation (“CryoCor”), and Helen Barold (“Barold”),
is entered into effective as of December 12, 2007 (the “Effective Date”).

RECITALS

WHEREAS, CryoCor and Barold desire to amend the Agreement to extend the
severance period following a termination of Barold’s employment without Cause.

AGREEMENT

NOW THEREFORE, in consideration of the benefits and mutual promises hereinafter
set forth, the parties hereto agree as follows:

 

1. Capitalized terms used but not otherwise defined in this Amendment shall have
the meanings given such terms in the Agreement.

 

2. Section 7.3 of the Agreement is hereby amended and restated in its entirety
as follows:

“7.3 Termination Without Cause by CryoCor or Resignation With Good Reason By
Barold/Severance. CryoCor may terminate Barold’s employment under this Agreement
without Cause or Barold may resign from her employment under this Agreement at
any time, with or without advance notice. In the event of such termination or in
the event of a resignation by Barold from her employment under this Agreement
with Good Reason (as defined below), Barold will receive the Base Salary then in
effect, prorated to the date of termination, and continuation of her Base Salary
for a period of twelve (12) months, payable in accordance with CryoCor’s regular
payroll cycle, provided that Barold: (a) complies with all surviving provisions
of this Agreement as specified in subsection 13.8 below; and (b) executes a
Release (as defined in Section 7.5 below). All other CryoCor obligations to
Barold will be automatically terminated and completely extinguished. For
purposes of this Agreement, “Good Reason” shall mean, with respect to Barold,
any one or more of the following: (a) without Barold’s express written consent,
a material diminution in Barold’s authority, duties or responsibilities;
(b) without Barold’s express written consent, the relocation of the principal
place of Barold’s service to a location that would increase her one-way commute
from her personal residence to the new principal place of work by more than 50
miles, or the imposition of travel requirements substantially more demanding of
Barold than such travel requirements existing immediately prior to the date of
the Change in Control; (c) any failure by the Company or its Affiliates to pay,
or any material reduction of Barold’s base salary in effect immediately prior to
the date of the Change in Control (unless reductions comparable in amount and
duration are concurrently made for all

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other employees of the Company and its Affiliates with responsibilities,
organizational level and title comparable to Barold’s); or (d) any breach by the
Company or its Affiliates of any agreement under which Barold provides services
to the Company. Notwithstanding the foregoing, Barold shall have “Good Reason”
for her resignation only if: (a) Barold notifies the Company in writing, within
30 days after the occurrence of one of the foregoing events, that she intends to
terminate her employment no earlier than 30 days after providing such notice;
(b) the Company does not cure such condition within 30 days following its
receipt of such notice or states unequivocally in writing that it does not
intend to attempt to cure such condition; and (c) Barold resigns from employment
within 30 days following the end of the period within which the Company was
entitled to remedy the condition constituting Good Reason but failed to do so.
The Board shall have the right to determine whether a resignation by Barold was
for Good Reason and its determination shall be final, binding and conclusive.
For purposes of this Agreement, “Affiliate” means, with respect to any specific
entity, any other entity that, directly or indirectly, through one or more
intermediaries, controls, is controlled by or is under common control with such
specified entity.”

 

3. Section 7.6 of the Agreement is hereby amended and restated in its entirety
as follows:

“7.6 Application of Code Section 409A. If Barold is a “specified employee”
within the meaning of Section 409A(a)(2)(B)(i) of the Code, any compensation and
benefits payable pursuant to this Agreement that are triggered by a separation
from service shall be accelerated to the minimum extent necessary so that
(i) the lesser of (A) the total cash severance payment amount, or (B) six months
of such installment payments are paid no later than March 15 of the calendar
year following such termination, and (ii) all amounts paid pursuant to the
foregoing clause (i) will constitute separate payments for purposes of
Section 1.409A-2(b)(2) of the Treasury Regulations and thus will be payable
pursuant to the “short-term deferral” rule set forth in Section 1.409A-1(b)(4)
of the Treasury Regulations. It is intended that if Barold is a “specified
employee” within the meaning of Section 409A(a)(2)(B)(i) of the Code at the time
of such separation from service the foregoing provision shall result in
compliance with the requirements of Section 409A(a)(2)(B)(i) of the Code because
payments to Barold will either be payable pursuant to the “short-term deferral”
rule set forth in Section 1.409A-1(b)(4) of the Treasury Regulations or will not
be paid until at least six months after separation from service.”

 

4. Except as specifically amended by this Amendment, the terms and conditions of
the Agreement shall remain in full force and effect.

 

5. This Amendment will be governed by and construed in accordance with the laws
of the United States and the State of California. Each party consents to the
jurisdiction and venue of the state or federal courts in San Diego, California,
if applicable, in any action, suit, or proceeding arising out of or relating to
this Amendment.

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6. This Amendment may be executed in two or more counterparts, each of which
shall be deemed an original, but all of which together shall constitute one and
the same instrument.

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IN WITNESS WHEREOF, the parties have executed this Amendment as of the Effective
Date.

 

CRYOCOR, INC. By:   /s/ Edward F. Brennan Name:   Edward F. Brennan Title:  
President and CEO

 

/s/ Helen Barold HELEN BAROLD