Exhibit 10.1
SECOND AMENDMENT TO
REAL ESTATE PURCHASE AND SALE AGREEMENT
     THIS SECOND AMENDMENT TO REAL ESTATE PURCHASE AND SALE AGREEMENT (this
“Amendment”) is entered into as of April 3, 2007 by and among SP-K Development,
LLC, SP-B1 Development, LLC, SP-A Development, LLC, SP-B2 Development, LLC, SP-D
Development, LLC, SP-E Development, LLC, SP-J Development, LLC, 110 Munson
Street, LLC, SP-C Development, LLC and Lyme Properties LLC, each a Delaware
limited liability company, and collectively, the “Seller” and BioMed Realty,
L.P., a Maryland limited partnership (the “Purchaser”), having an office at
17140 Bernardo Center Drive, Suite 222, San Diego, California 92128, with a
facsimile number of (858) 485-9843. The Seller has an office c/o Lyme Properties
LLC, 101 Main Street, 18th floor, Cambridge, MA 02142 Attn: Robert L. Green,
with a facsimile number of (617) 225-2133.
     The parties desire to make certain amendments to a certain Real Estate
Purchase and Sale Agreement entered into by them with an Effective Date of
January 29, 2007, as amended by an amendment dated February 16, 2007 (the
“P&S”).
     Capitalized terms used but not otherwise defined herein shall have the
meanings given such terms in the P&S.
     In consideration of the mutual promises hereinafter set forth and for other
good and valuable consideration, the receipt and sufficiency of which are hereby
acknowledged, the undersigned agree as follows:
     1. Definition of Real Property. The definition of Real Property in the P&S
is hereby amended by modifying the last sentence of such definition to read as
follows:
“Exhibit A respectively describes the following: Tract K, Tract B-1, Tract J and
110 Munson.”
     2. Section 2.2. Section 2.2(a) of the P&S is hereby amended by amending and
restating such Section as follows:
     “Section 2.2 Purchase Price. (a) The purchase price for the Property shall
be the sum of Twenty-one Million Dollars ($21,000,000.00) (the “Purchase
Price”); provided, however, that if the Closing is for any reason not
intentionally caused by Seller delayed beyond 10:00 a.m. EST on April 4, 2007,
the Purchase Price shall increase by Two Hundred Fifty Thousand Dollars
($250,000), and shall likewise be increased by such amount for each additional
day of delay at such time on each day

 

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thereafter. Subject to adjustments and apportionments set forth in this
Agreement, the Purchase Price shall be paid on the Closing Date by wire transfer
of immediately available federal funds to such account(s) of Seller as Seller
designates in writing to Purchaser.”
     3. Section 6.1(e). Section 6.1(e) is hereby amended by amending and
restating such Section in its entirety as follows:
     “Purchaser shall have received from Science Park Development Corporation
and Olin Corporation respectively a “TDA Consent” substantially in the forms
attached as Schedule 6.1(e), dated no earlier than the Effective Date.”
     4. Section 6.1(f) and Definitions. Section 6.1(f) of the P&S is hereby
deleted in its entirety. The P&S is hereby further amended by deleting the
phrases ARDA Consent, ARDA Estoppel Provisions and ARDA Party in all instances
where they appear in the P&S.
     5. Section 6.1. Section 6.1 of the P&S is hereby amended by adding a new
clause 6.1(o) as follows:
“Seller shall have delivered to Buyer a written acknowledgement, in form
attached as Schedule 6.1(o), from Science Park Development Corporation
acknowledging that (1) all conditions precedent to the effectiveness of the
consent set forth in that certain letter dated April 2, 2007 from David
Silverstone to David E. Clem have been satisfied in full, and (2) the ARDA shall
have been terminated (“SPDC Closing Letter”).”
     6. Section 6.2. Section 6.2(c) is hereby deleted and Section 6.2(d) of the
P&S is hereby amended by replacing such Section with the following:
“Purchaser shall have delivered to Science Park Development Corporation letters
of credit as security for Ground Leases in the amounts of $25,000 for Tract B-1
and $27,908 for Tract J.”
     7. Section 8.2. Section 8.2 of the P&S is hereby amended, first, by
deleting Section 8.2(i) in its entirety and replacing it with the following:
“The SPDC Closing Letter,” and second, by adding Appendices A and B attached
hereto as deliveries required from Seller (and Purchaser as appropriate) at
Closing.
     8. Exhibits A. The P&S is hereby amended by deleting Exhibit A in its
entirety and replacing it with Exhibit A attached hereto.
     9. Schedule 6.1(d). The P&S is hereby amended by deleting Schedule 6.1(d)
in its entirety and replacing it with Schedule 6.1(d) attached hereto.

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     10. Schedule 6.1(e). The P&S is hereby amended by deleting Schedule 6.1(e)
in its entirety and replacing it with Schedule 6.1(e) attached hereto.
     11. Schedule 6.1(f). The P&S is hereby amended by deleting Schedule 6.1(f)
in its entirety.
     12. Schedule 6.1(o). The P&S is hereby amended by adding Schedule 6.1(o)
attached hereto.
     13. Schedule 7.2(b)(iv)-1. The P&S is hereby amended by deleting Schedule
7.2(b)(iv)-1 in its entirety and replacing it with 7.2(b)(iv)-1 attached hereto.
     14. Schedule 7.2(b)(iv)-3. The P&S is hereby amended by deleting Schedule
7.2(b)(iv)-3 in its entirety and replacing it with 7.2(b)(iv)-3 attached hereto.
     15. Schedule 7.2(b)(iv)-2. The P&S is hereby amended by deleting from
Schedule 7.2(b)(iv)-2 the Miscellaneous Consultant Agreement for William A.
Berry & Sons, Inc. dated May 29, 2006 (abatement and demolition).
     16. Schedule 8.2(b). The P&S is hereby amended by deleting Schedule 8.2(b)
in its entirety and replacing it with Schedule 8.2(b) attached hereto. A certain
Exhibit C at the end of Schedule 8.2(b) shall be Exhibit C to Schedule 8.2(b).
     17. Schedule 8.2(e). The P&S is hereby amended by deleting Schedule 8.2(e)
in its entirety and replacing it with Schedule 8.2(e) attached hereto.
     18. Ratification. Upon the execution of this Amendment by Seller and
Purchaser, the P&S (including, without limitation, the Updates distributed to
Purchaser on February 13, 2007), as amended hereby, shall be ratified and
confirmed.
[Remainder of Page Left Intentionally Blank]

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     IN WITNESS WHEREOF, Seller and Purchaser hereto have executed this
Amendment as of the date first written above.

            SELLER:

SP-K DEVELOPMENT, LLC, a Delaware limited liability company
      By:   Lyme Properties LLC, a New Hampshire limited liability company, its
sole Manager                               By:   /s/ GEORGE LIGHTBODY        
Name:   George Lightbody        Its:   CFO       Date:   4/3, 2007    

            SP-B1 DEVELOPMENT, LLC, a Delaware limited liability company
      By:   Lyme Properties LLC, a New Hampshire limited liability company, its
sole Manager                               By:   /s/ GEORGE LIGHTBODY        
Name:   George Lightbody        Its:   CFO       Date:   4/3, 2007    

            SP-A DEVELOPMENT, LLC, a Delaware limited liability company
      By:   Lyme Properties LLC, a New Hampshire limited liability company, its
sole Manager                               By:   /s/ GEORGE LIGHTBODY        
Name:   George Lightbody        Its:   CFO       Date:   4/3, 2007  

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            SP-B2 DEVELOPMENT, LLC, a Delaware limited liability company
      By:   Lyme Properties LLC, a New Hampshire limited liability company, its
sole Manager                               By:   /s/ GEORGE LIGHTBODY        
Name:   George Lightbody        Its:   CFO       Date:   4/3, 2007    

            SP-D DEVELOPMENT, LLC, a Delaware limited liability company
      By:   Lyme Properties LLC, a New Hampshire limited liability company, its
sole Manager                               By:   /s/ GEORGE LIGHTBODY        
Name:   George Lightbody        Its:   CFO       Date:   4/3, 2007    

            SP-E DEVELOPMENT, LLC, a Delaware limited liability company
      By:   Lyme Properties LLC, a New Hampshire limited liability company, its
sole Manager                               By:   /s/ GEORGE LIGHTBODY        
Name:   George Lightbody        Its:   CFO       Date:   4/3, 2007  

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            SP-J DEVELOPMENT, LLC, a Delaware limited liability company
      By:   Lyme Properties LLC, a New Hampshire limited liability company, its
sole Manager                               By:   /s/ GEORGE LIGHTBODY        
Name:   George Lightbody        Its:   CFO       Date:   4/3, 2007       110
MUNSON STREET, LLC, a Delaware limited liability company               By:  
Lyme Properties LLC, a New Hampshire limited liability company, its sole Manager
                              By:   /s/ GEORGE LIGHTBODY         Name:   George
Lightbody        Its:   CFO       Date:   4/3, 2007    

            SP-C DEVELOPMENT, LLC, a Delaware limited liability company
      By:   Lyme Properties LLC, a New Hampshire limited liability company, its
sole Manager                               By:   /s/ GEORGE LIGHTBODY        
Name:   George Lightbody        Its:   CFO       Date:   4/3, 2007  

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            LYME PROPERTIES LLC, a New Hampshire limited liability company
      By:   /s/ GEORGE LIGHTBODY         Name:   George Lightbody        Its:  
CFO       Date:   4/3, 2007       PURCHASER:

BIOMED REALTY, L.P.
      By:   /s/ ALAN D. GOLD         Name:   Alan D. Gold        Title:   CEO &
President       Date:   April 4, 2007    

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