Exhibit 10.1

(NORTHWEST BIOTHERAPEUTICS LOGO) [c71278c7127801.gif]

         
Northwest
  t (425) 608-3008   www.nwbio.com
Biotherapeutics, Inc.
  (800)-519-0755   OTCBB: NWBO
 
  f (425) 608-3009    
18701 120th Avenue NE
       
Suite 101
       
Bothell, WA 98011
       

September 14, 2007
Dear Mr. Deasey:
The Board of Directors proposes to enter into an employment agreement effective
October 1, 2007 with you for four years of service in the senior management of
the Company, with the following key terms:

  •   Title: Chief Financial Officer and Senior Vice President of Finance     •
  Board of Directors seat: Effective October 1, pending BOD approval     •  
Term: 4 years     •   Annual Salary: $275,000 (subject to potential increases
based on annual review by the Compensation Committee of the Board of Directors)
    •   Location of Employment: Bethesda, MD     •   Bonuses: To be determined
in the Board’s discretion for extraordinary and unanticipated accomplishments.  
  •   Equity: Sufficient options to result in your holding 1.0% of the stock of
the Company, on a fully diluted basis (i.e., including all of the shares
issuable under options and warrants outstanding or reserved in the employee
pool) immediately after Admission of the AIM Placing Shares for trading. (The
number of options is thus anticipated to be approximately 769,208.) Vesting
shall occur over a 4-year period as defined in the Stock Option Grant Notice,
with 25% vesting on the first anniversary of your full time employment and the
remaining 75% vesting monthly over the 36 months following the first
anniversary.     •   Change in Control: For purposes of this agreement Change in
Control shall mean the merger or acquisition of the Company by another entity in
whole or in part so as to hold majority ownership of the Company. Upon such an
event if it should occur in the first year of employment which would be prior to
vesting of the first 25% of options, this first year vesting of 25% of options
shall be accelerated and vested.     •   Termination: Employment will be at
will. The Company may terminate your employment with no notice “For Cause” or
with 90 days notice “Without Cause.” “Cause” is defined as, but not limited to,
malfeasance, material non-performance or materially inadequate performance of
your duties following written notice or other communication from the Board of
such non-performance or inadequate performance and a reasonable period of time
to cure it one time.

 

 

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  •   Notice of resignation: If you resign, you will give at least 60 days
advance notice if resignation is prior to October 1, 2009, and 30 days after
October 1, 2009. During the 60 or 30 days prior to departure, you will devote
best efforts, in good faith, to the Company’s business and any personnel
transition. Failure to give the 60 or 30 days notice will result in clawback of
any bonuses paid to you and option vesting that occurred in the 6 months prior
to the resignation announcement.     •   Effect of termination or resignation on
options: Vesting of your stock options will cease upon the termination of your
employment or resignation.

  •   If your employment is terminated For Cause, options which are already
vested as of the date of termination shall expire one business day after such
termination.     •   If your employment is terminated Without Cause, options
will vest until the last day of your employment and will be exercisable for up
to 120 days following your termination Without Cause, so long as you execute a
separation and release agreement reasonably acceptable to the Company.     •  
If you resign or your 4 year contract expires, the vesting of your options will
cease on the last day of your employment. If your resignation complies with the
60 — or 30-day notice, best efforts and good faith requirements above, your
options will be exercisable for 60 days following the last day of your
employment so long as you do not work for or with a Competing Company (as
defined below) in any capacity (employee, director, adviser, collaborator, etc.)
during the one year following the termination of your employment. The term
“Competing Company” means a business that is developing immunotherapies for
cancer. If your resignation does not comply with the notice, best efforts and
good faith requirements above, your options will expire one business day after
your resignation.

  •   Outside activities: During the term of this Agreement, you shall not
engage in any outside business activities except with express prior approval of
the Board. It is recognized that you have limited transitional activities with
your former employer and the Company acknowledges that these transitional
activities are not in conflict with this specific clause.     •  
Non-competition: You agree not to work for or with any Competing Company (as
defined above) for 1 year after resignation, termination for cause or expiration
of your employment with the Company. You must execute a non-competition
agreement with the Company providing for this arrangement.     •   Assignment of
inventions; confidentiality: All inventions conceived or developed by you during
your employment by the Company must be assigned to the Company. You must also
execute the Company’s standard invention assignment agreement and a limited
power of attorney enabling the Company to make filings and take actions
necessary to implement your assignments of inventions. You must also execute the
standard confidentiality agreement.

 

 

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  •   Vacation and sick leave: 4 weeks of vacation, no carryover (use it or lose
it) except in special circumstances with prior Board approval and then only up
to 2 weeks; 2 weeks of sick leave, to be used only for sickness and medical
appointments for yourself or family members.

The Board hopes that you will find these terms agreeable. If so, please indicate
your acceptance by countersigning below. We look forward to your continued
important role in the Company for the next several years.
Sincerely,

     
NWBT BOARD OF DIRECTORS
  I have read and accept this employment offer:
By:
  By:
 
   
 
   
 
   
Name: Alton L. Boynton
  Name:
Title: President & CEO
   
Date: September 14, 2007
  Date: