Exhibit 10.4

 

CONSULTING AGREEMENT

 

This CONSULTING AGREEMENT (the “Agreement”) is made and entered into as of the
28th day of December 2012 by and between Gabriele M. Cerrone (“Consultant”) and
Synergy Pharmaceuticals Inc., a Delaware corporation (the “Company”).

 

WHEREAS, the Company desires to engage Consultant to provide certain consulting
services, and Consultant is willing to be engaged by the Company to provide such
services, on the terms and conditions set forth below;

 

WHEREAS, the Company understands that the Consultant will be performing
substantially all of his consulting services pursuant to this Agreement outside
of the U.S;

 

WHEREAS, the Consultant has previously entered into a consulting agreement with
the Company as of March 11, 2009, as amended by the Amended and Restated
Consulting Agreement entered into with the Company as of February 10, 2010 and
the Second Amended and Restated Employment Agreement with the Company as of
May 2, 2011(the “Prior Consulting Agreement”); and

 

WHEREAS, the parties wish to enter into a new Agreement between the Consultant
and the Company in its entirety, on the terms and conditions contained in this
Agreement, which will supersede the Prior Consulting Agreement and all prior
agreements and understandings between the parties, oral or written.

 

NOW, THEREFORE, in consideration of the mutual covenants and agreements
contained herein, the receipt and sufficiency of which are hereby acknowledged,
the parties hereto agree as follows:

 

1.                                      Purpose: The Company hereby engages
Consultant for the term specified in Paragraph 2 hereof to render consulting
advice to the Company relating to business development, corporate finance and
capital markets matters upon the terms and conditions set forth herein.

 

2.                                      Effective Date and Term:

 

2.1                               Effective Date.  This Agreement became
effective as of January 1, 2013 (the “Effective Date”).

 

2.2                               Term.  Unless earlier terminated pursuant to
Section 10 hereof, the term of this Agreement shall commence on the Effective
Date and shall continue from the Effective Date to December 31, 2016 (the
“Initial Term”).  This Agreement shall thereafter be automatically renewed for
successive one year periods (each a “Renewal Term”) unless either party shall
notify the other in writing of its intention not to renew this Agreement (a
“Non-renewal Notice”), which notice shall be given at least 60 days prior to the
end of the then current term (the “Expiration Date”).  The period from the

 

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Effective Date to the Expiration Date, including the Renewal Terms, if any, is
referred to herein as the “Term.”

 

3.        Duties of Consultant:  During the term of this Agreement, the
Consultant shall devote such portion of his business time and attention to
affairs of the Company reasonably necessary to provide the Company with such
regular and customary business development, strategic planning, capital markets
and corporate finance consulting advice as is reasonably requested by the
Company’s management and Board of Directors, provided that Consultant shall not
be required to undertake duties not reasonably within the scope of this
Agreement.  So long as the Consultant serves as a member of the Company’s Board
of Directors,  Consultant shall serve as Chairman of the Board; provided, at the
request of all of the members of the Board of Directors (not counting the
Consultant), the Consultant will relinquish his title as Chairman to the
Company’s duly appointed chief executive officer, and accept the title of Vice
Chairman.

 

3.1.  Permissible Services.   The Consultant’s services will include advising
the Company’s Board of Directors and senior management on the following matters:

 

(i)

 

in-licensing and out-licensing technologies and compounds;

(ii)

 

capitalization and corporate organization of the Company;

(iii)

 

structure and pricing of offerings of the Company’s securities in public and
private transactions;

(iv)

 

alternative uses of corporate assets;

(v)

 

structure and use of debt;

(vi)

 

application and maintenance of listing of the Company’s stock in securities
exchanges and other appropriate markets;

(vii)

 

strategic planning

(viii)

 

management recruitment and compensation; and

(ix)

 

presentations to institutional and professional individual investors in Europe,
Asia and the U.S.

 

3.2          Prohibited Services.  The services to be rendered by the Consultant
to the Company shall not (unless the Consultant is appropriately licensed,
registered or there is an exemption available from such licensing or
registration) include, directly or indirectly: any activities which require the
Consultant to register as a broker-dealer under the Securities Exchange Act of
1934, as amended.

 

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4.             Consulting Fee:  :

 

4.1.                 Base Consulting Fee.  In consideration for the services
rendered by Consultant to the Company pursuant to this Agreement, the Company
agrees to pay Consultant the annual sum of $425,000 at the rate of $35,416.67
per month commencing on the Effective Date (“Base Consulting Fee”). The
Consultant’s Base Consulting Fee may be increased, but not decreased by the
Board or the Compensation Committee of the Board (the “Compensation
Committee”).  Once increased, such increased amount shall constitute the
Consultant’s Base Consulting Fee and shall not be decreased. The Company will
include the shares of equity securities of the Company which may be issued upon
the exercise of the options held by Consultant in any registration statement
under the Securities Act of 1933 which includes securities issuable to any other
executive officer of the Company.

 

4.2.                 Incentive Payments.

 

(a)           Annual Bonus.     Consultant shall be eligible to earn a cash
bonus of up to 50% of his Base Consulting Fee per full calendar year during the
Term based on meeting performance objectives and bonus criteria to be mutually
identified by Consultant and the Compensation Committee.  The bonus shall be
determined on or before March 1 of each year of the Employment Term commencing
January 1, 2013 and paid on or before April 14 of each year.

 

(b)           Realization Bonus.

 

(i)            In the event during the Term of this Agreement the Company enters
into either a out-license agreement for any of its technology that grants
exclusive marketing rights to a third party (and the license fees the Company
contracts to receive (disregarding any contingencies to such payment) equals or
exceeds $50 million) or enters into a joint venture in which the Company
contributes such rights to the joint venture, in each case where the Enterprise
Value (defined below) equals or exceeds the minimum value of $250 million, the
Consultant shall accrue a bonus in an amount determined by multiplying the
Enterprise Value (defined below) in the case of a joint venture or the sum of
the license fees actually received, in the case of an out-license, as the case
may be, by 0.5% (one half percent).

 

(ii)           In the event during the Term of this Agreement the Company:

 

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(A) engages in (i) a merger transaction, as a result of which the stockholders
of the Company existing immediately before the consummation of such merger own
beneficially less than 20% of the stock of the ultimate parent of the surviving
entity immediately after the consummation of the merger where the Enterprise
Value equals or exceeds a minimum value of $400 million or (ii) a sale of
substantially all of the assets of the Company where the Enterprise Value equals
or exceeds a minimum value of $400 million, the Consultant shall accrue a bonus
in an amount determined by multiplying the Enterprise Value by 2.5% (a “Sale
Transaction”); or

 

(B)  engages in (i) a merger transaction, as a result of which the stockholders
of the Company existing immediately before the consummation of such merger own
beneficially 20% or more of the stock of the ultimate parent of the surviving
entity immediately after the consummation of the merger where the Enterprise
Value of the Company either at the effective date of the transaction or 12
months after the effective date of the transaction)  equals or exceeds a minimum
value of $250 million or (ii) a sale of substantially all of the assets of the
Company where the Enterprise Value equals or exceeds a minimum value of $250
million, the Consultant shall accrue a bonus in an amount determined by
multiplying the Enterprise Value by 2.5% (a “Combination Transaction”).

 

(iii)          The accrued bonuses shall be payable to Consultant: (a) in the
same form of the consideration received by the Company’s stockholders in full
contemporaneously at the closing of any joint venture, Sale Transaction or
Combination Transaction; or (b) in cash 5 full business days after the Company’s
receipt of license fees at the rate of 0.5% of license fees actually received. 
The expiration or termination of this Agreement shall not terminate or diminish
the Consultant’s right to receive bonus payments with respect to out license
fees collected or the consummation of any joint venture, Sale Transaction or
Combination Transaction after the termination or expiration of this Agreement
provided the Company has entered into an agreement for such a transaction any
time during the Term or 90 days thereafter.

 

(iv)  The “Enterprise Value” in the case of a Change in Control in which
consideration is payable to the Company in respect of its assets or business,
shall mean the total cash and non-cash (including, without limitation, the
assumption of debt) consideration received by the Company or in the case of a
Change in Control in which consideration is payable to the Company’s
stockholders, the total cash and non-cash (including, without limitation, the
assumption of debt) consideration payable to the Company’s stockholders.
“Enterprise Value” shall also include, if applicable, any cash or non-cash
consideration payable to the

 

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Company or to the Company’s stockholders on a contingent, earnout or deferred
basis. To the extent that any consideration in a transaction is not received in
cash upon the consummation of the Change in Control, the value of such non-cash
consideration for purposes of calculating the Enterprise Value will be
determined by the independent Board of Directors of the Company prior to the
Change in Control in good faith in consultation with an independent investment
bank or financial advisor retained by Board of Directors in connection with the
Change in Control transaction. In the event that less than 100% of the stock or
assets of the Company is purchased in the Change in Control transaction, the
Enterprise Value shall be extrapolated from the percentage of the Company’s
capital stock or assets impacted in such Change in Control transaction to
determine if the applicable threshold was exceeded, but the Transaction Fee
shall be calculated based on the actual consideration received by the Company or
shareholders, as the case may be. Section 4.2(b), however, shall not apply to
any event resulting in a Change in Control in which neither the Company nor its
stockholders receives consideration either upon, or in connection with, the
occurrence or consummation of the event resulting in a Change in Control.

 

(v)  For purposes of Section 4.2(b)(ii)(B), Enterprise Value at any time
subsequent to the effective date of a transaction shall be computed by reference
to the market capitalization of the combined entity (based on an average closing
price of the combined entities common stock for a period of 20 consecutive
trading days) multiplied by the quotient of the number of combined entities
shares of common stock and common stock equivalents issued to the Company’s
stockholders in the transaction divided by the total number of shares of the
common stock and common stock equivalents outstanding on the effective date of
the transaction, on a fully diluted basis.

 

(c)           Options.       The Compensation Committee will consider grants of
options to the Consultant no less frequently than annually commencing January 1,
2013.

 

5.             Expenses and Services:

 

5.1                               Consultant is authorized to incur reasonable
expenses in carrying out his duties and responsibilities under this Agreement,
including, without limitation, expenses for travel (at the fare class no less
favorable than that of other executive officers of the Company), cellular
telephone (including access charges and business calls), electronic market data
services consisting of a full office-based and portable Bloomberg information
services, the cost associated with accessing office facilities and
administrative assistance outside of the Company’s principal executive offices
at such times that the

 

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Consultant is attending to matters within the scope of this Agreement and
business entertainment.  Additionally, the Consultant is authorized to incur
reasonable expenses for the attendance of conferences in fields relate to
technology of interest to the Company, finance of biotechnology ventures, and
similar events related to Consultant’s duties and responsibilities as Consultant
deems necessary.  Company will reimburse Consultant for all such expenses upon
presentation by Consultant of appropriately itemized accounts of such
expenditures or the Company will pay such expenses directly.

 

5.2                               During the Term, the Company will at its sole
expense provide the Consultant with computing hardware and software tools,
office facilities and qualified, access to Company information and financial
records and an experienced administrative assistant and such legal and
accounting support services as is deemed appropriate by the Consultant.  Such
services and facilities will not be diminished without the Consultant’s prior
consent.

 

5.3                               In the event this Agreement is terminated
other than for Cause or voluntarily by the Consultant, the Company, in addition
to any other termination benefit, will make a lump sum payment to Consultant
equal to the higher of the aggregate amount of the sum of average monthly cost
during the three full months immediately preceding such termination of providing
the services to Consultant set forth in Section 5.1 and Consultant’s reimbursed
expenses set forth in Section 5.2  for the then remaining term of this Agreement
or twelve times the sum of average monthly cost during the three full months
immediately preceding such termination of providing the services to Consultant
set forth in Section 5.1 and Consultant’s reimbursed expenses set forth in
Section 5.2.  Such lump sum payments shall be made no later than 30 days after
termination. In the event of a disagreement between the Company as to the amount
of such lump sum payment, the Company shall pay the amount as to which there is
no dispute, pending the settlement of any amounts as to which there is a
dispute.

 

6.             Liability of Consultant:  The Company acknowledges that all
opinions and advice (written or oral) given by Consultant to the Company in
connection with Consultant’s engagement are intended solely for the benefit and
use of the Company in considering the transaction to which they relate, and the
Company agrees that no person or entity other than the Company shall be entitled
to make use of or rely upon the advice of Consultant to be given hereunder, and
no such opinion or advice shall be used for any other purpose or reproduced,
disseminated, quoted or referred to at any time, in any manner or for any
purpose, nor may the Company make any public references to Consultant, or use

 

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Consultant’s name in any annual reports or any other reports or releases of the
Company without Consultant’s prior written consent.  Consultant’s maximum
liability shall not exceed the cash payments received from the Company.

 

7.             Consultant’s Services to Others:  The Company acknowledges that
Consultant and its affiliates are in the business of investing and providing
financial services and consulting advice to others.  Nothing herein contained
shall be construed to limit or restrict Consultant in conducting such business
with respect to others, or in rendering such advice to others.

 

8.             Company Information:

 

a.             The Company recognizes and confirms that, in advising the Company
and in fulfilling his engagement hereunder, Consultant will use and rely on
data, material and other information furnished to Consultant by the Company. 
The Company acknowledges and agrees that in performing his services under this
engagement, Consultant may rely upon the data, material and other information
supplied by the Company without independently verifying the accuracy,
completeness or veracity of same.  The Company agrees to notify Consultant in
writing via overnight courier, facsimile or e-mail of any material event and/or
change with in twenty-four hours of its occurrence.

 

b.             Consultant recognizes and acknowledges that by reason of
Consultant’s retention by and service to the Company before, during and, if
applicable, after the Term, Consultant will have access to certain confidential
and proprietary information relating to the Company’s business, which may
include, but is not limited to, trade secrets, trade “know-how,” product
development techniques and plans, formulas, customer lists and addresses, 
financing services, funding programs, cost and pricing information, marketing
and sales techniques, strategy and programs, computer programs and software and
financial information relating to the field of in which the Company is actually
engaged in research, development, collaboration or sales at the time of such
disclosure (collectively referred to as “Confidential Information”).  Consultant
acknowledges that such Confidential Information is a valuable and unique asset
of the Company and Consultant covenants that it will not, unless expressly
authorized in writing by the Company, at any time during the Consulting Term use
any Confidential Information or divulge or disclose any Confidential Information
to any person, firm or corporation except in connection with the performance of
Consultant’s duties for the Company and in a manner consistent with the
Company’s policies regarding Confidential Information.  Consultant also
covenants that at any time after the termination of this Agreement, directly or
indirectly, it will not use any Confidential Information or divulge or disclose
any Confidential Information to any person, firm or corporation, unless such
information is in the public domain through no fault of Consultant or except
when required to do so by a court of law, by any governmental agency having
supervisory authority over the business of the Company or by any administrative
or legislative body (including a committee

 

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thereof) with apparent jurisdiction to order Consultant to divulge, disclose or
make accessible such information.  All written Confidential Information
(including, without limitation, in any computer or other electronic format)
which comes into Consultant’s possession during the Consulting Term shall remain
the property of the Company.  Except as required in the performance of
Consultant’s duties for the Company, or unless expressly authorized in writing
by the Company, Consultant shall not remove any written Confidential Information
from the Company’s premises, except in connection with the performance of
Consultant’s duties for the Company and in a manner consistent with the
Company’s policies regarding Confidential Information.  Upon termination of this
Agreement, the Consultant agrees to return immediately to the Company all
written Confidential Information (including, without limitation, in any computer
or other electronic format) in Consultant’s possession.  .

 

9.             Consultant an Independent Contractor:  Consultant shall perform
its services hereunder as an independent contractor and not as an employee of
the Company or an affiliate thereof.  It is expressly understood and agreed to
by the parties hereto that Consultant shall have no authority to act for,
represent or bind the Company or any affiliate thereof in any manner, except as
may be agreed to expressly by the Company in writing from time to time.

 

10.          Termination:

 

10.1        Termination Without Cause or for Good Reason.

 

(a)           If this Agreement is terminated by the Company other than for
Cause (as defined in Section 10.4 hereof) or as a result of Consultant’s death
or Permanent Disability (as defined in Section 10.2 hereof), or if Consultant
terminates his engagement for Good Reason (as defined in Section 10.1
(b) hereof) prior to the Expiration Date, Consultant shall receive or commence
receiving as soon as practicable in accordance with the terms of this Agreement:

 

(i)                                     a severance payment (the “Severance
Payment”), which amount shall be paid in a cash lump sum within ten (10) days of
the date of termination, in an amount equal to the higher of the aggregate
amount of the Consultant’s Base Consulting Fee for the then remaining term of
this Agreement or twelve times the average monthly Base Consulting Fee paid or
accrued during the three full months immediately preceding such termination;

 

(ii)           expense compensation, which shall be paid in a lump sum payment
within ten (10) days of the date of termination, in an amount equal to the
higher of the aggregate amount of the sum of average monthly cost during the
three full

 

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months immediately preceding such termination of providing the services to
Consultant set forth in Section 5.1 and Consultant’s reimbursed expenses set
forth in Section 5.2  for the then remaining term of this Agreement or twelve
times the sum of average monthly cost during the three full months immediately
preceding such termination of providing the services to Consultant set forth in
Section 5.1 and Consultant’s reimbursed expenses set forth in Section 5.2;

 

(ii)           immediate vesting of all unvested stock options and the extension
of the exercise period of such options to the later of the longest period
permitted by the Company’s stock option plans or ten years following the
Termination Date;

 

(iii)          payment in respect of consulting fees and bonus earned but not
yet paid (the “Consulting Payment”) which amount shall be paid in a cash lump
sum within ten (10) days of the date of termination; and

 

(iv)          payment of the cost of comprehensive medical insurance for
Consultant for the greater of the then remaining term of this Agreement or for a
period of twelve months following the termination.

 

(b)           For purposes of this Agreement, “Good Reason” shall mean any of
the following (without Consultant’s express prior written consent):

 

(i)                                     Any material breach by Company of any
provision of this Agreement, including any material reduction by Company of
Consultant’s duties or responsibilities (except in connection with the
termination of Consultant’s employment for Cause, as a result of Permanent
Disability, as a result of Consultant’s death or by Consultant other than for
Good Reason);

 

(ii)           A reduction by the Company in Consultant’s Base Consulting Fee or
any failure of the Company to reimburse Consultant for material expenses
described in Section 5.1 or provide the services described in Section 5.2 of
this Agreement;

 

(iii)          The failure by the Company to obtain the specific assumption of
this Agreement by any successor or assign of Company as provided for in
Section 11 hereof; or

 

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(iv)          Upon a Change of Control of Company (as such term is hereinafter
defined).

 

(c)                                  The following provisions shall apply in the
event the payments provided in Section 10.1 (a) becomes payable to the
Consultant:

 

(i)                                     In the event the severance payments
provided for in subsection 10.1(a)  above cannot be finally determined on or
before the tenth day following such termination, the Company shall pay to the
Consultant on such day an estimate, as determined in good faith by the Company
of the minimum amount of such payments and shall pay the remainder of such
amount (together with interest at the Federal short-term rate provided in
Section 1274(d)(7)(C)(1) of the Code) as soon as the amount thereof can be
determined but in no event later than the thirtieth day after the Date of
Termination. In the event the amount of the estimated payment exceeds the amount
subsequently determined to have been due, such excess shall constitute a loan by
the Company to the Consultant payable on the fifth day after demand by the
Company (together with interest at the Federal short-term rate provided in
Section 1274(d)(7)(C)(1) of the Code).

 

(ii)           If the payment of the Total Payments (as defined below) will be
subject to the tax (the “Excise Tax”) imposed by Section 4999 of the Code, the
Company shall pay the Consultant on or before the tenth day following the Date
of Termination, an additional amount (the “Gross-Up Payment”) such that the net
amount retained by the Consultant, after deduction of any Excise Tax on Total
Payments and any federal and state and local income tax and Excise Tax upon the
payment provided for by this paragraph, shall be equal to the Total Payments.
For purposes of determining whether any of the payments will be subject to the
Excise Tax and the amount of such Excise Tax, (A) any payments or benefits
received or to be received by the Consultant in connection with a Change in
Control of the Company or the Consultant’s termination of employment, whether
payable pursuant to the terms of Section 10 of this Agreement or any other plan,
arrangement or agreement with the Company, its successors, any person whose
actions result in a Change in Control of the Company or any corporation
affiliated (or

 

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which, as a result of the completion of transaction causing such a Change in
control, will become affiliated) with the Company within the meaning of Section
1504 of Code (the “Total Payments”) shall be treated as “parachute payments”
within the meaning of Section 28OG(b)(2) of the Code, and all “excess parachute
payments” within the meaning of Section 28OG(b)(1) shall be treated as subject
to the Excise Tax, unless, in the opinion of tax counsel selected by the
Company’s independent auditors and acceptable to the Consultant, the Total
Payments (in whole or in part) do not constitute parachute payments, or such
excess parachute payments (in whole or in part) represent reasonable
compensation for services actually rendered within the meaning of Section
28OG(b)(4) of the Code either in their entirety or in excess of the base amount
within the meaning of Section 28OG(b)(3) of the Code, or are otherwise not
subject to the Excise Tax, (B) the amount of the Total Payments that shall be
treated as subject to the Excise Tax shall be equal to the lesser of (I) the
total amount of the Total Payments or (II) the amount of excess parachute
payments or benefit shall be determined by the Company’s independent auditors in
accordance with the principles of Section 28OG(d)(3) and (4) of the Code. For
purposes of determining the amount of the Gross-Up Payment, the Consultant shall
be deemed to pay federal income taxes at the highest marginal rate of federal
income taxation in the calendar year in which the Gross-Up Payment is to be made
and state and local income taxes at the highest marginal rate of taxation in the
state and locality of the Consultant’s residence an the Date of Termination, net
of the maximum reduction in federal income taxes which could be obtained from
deduction of such state and local taxes. In the event the Excise Tax is
subsequently determined to be less than the amount taken into account hereunder
at the time of termination of the Consultant’s employment, the Consultant shall
repay to the Company at the time the amount of such reduction in Excise Tax is
finally determined the portion of the Gross-Up Payment that can be repaid such
that the Consultant remains whole on an after-tax basis following such repayment
(taking into account any reduction in income or excise taxes to the Consultant
from such repayment) plus interest on the amount of such repayment at the
Federal short-term rate provided in Section 1274(d)(1)(C)(i) of the Code. In the
event the Excise Tax is determined to exceed the amount taken into account
hereunder at the time of the termination

 

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of the Consultant’s employment (including by reason of any payment the existence
or amount of which cannot be determined at the time of the Gross-Up Payment),
the Company shall make an additional gross-up payment in respect of such excess
(plus any interest payable with respect to such excess) at the time that the
amount of such excess is finally determined.

 

10.2        Permanent Disability.  If Consultant becomes totally and permanently
disabled (as defined in the Company’s disability benefit plan applicable to
senior executive officers as in effect on the date thereof) (“Permanent
Disability”), Company or Consultant may terminate this Agreement on written
notice thereof, and Consultant shall receive or commence receiving, as soon as
practicable:

 

(i)            amounts payable pursuant to the terms of the disability insurance
policy or similar arrangement which Company maintains for the Consultant, if
any, during the term hereof;

 

(ii)           the Consulting Payment which shall be paid to Consultant as a
cash lump sum within 30 days of such termination; and

 

(iii)          immediate vesting of all unvested stock options.

 

10.3        Death.    In the event of Consultant’s death during the term of his
employment hereunder, Consultant’s estate or designated beneficiaries shall
receive or commence receiving, as soon as practicable in accordance with the
terms of this Agreement:

 

(i)            a payment equal to one year’s Base Consulting Fee which shall be
paid within 30 days of such termination;

 

(ii)           any death benefits provided under the Consultant benefit
programs, plans and practices in which the Consultant has an interest, in
accordance with their respective terms;

 

(iii)          the Consulting Payment which shall be paid to Consultant’s estate
as a cash lump sum within 30 days of such termination; and

 

(iv)          such other payments under applicable plans or programs to which
Consultant’s estate or designated beneficiaries are entitled pursuant to the
terms of such plans or programs.

 

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10.4        Voluntary Termination by Consultant: Discharge for Cause.    The
Company shall have the right to terminate this Agreement for Cause (as
hereinafter defined). In the event that Consultant’s employment is terminated by
Company for Cause, as hereinafter defined, or by Consultant other than for Good
Reason or other than as a result of the Consultant’s Permanent Disability or
death, prior to the Termination Date, Consultant shall be entitled only to
receive, as a cash lump sum within 30 days of such termination, the Consulting
Payment.  As used herein, the term “Cause” shall be limited to (i) willful
malfeasance or willful misconduct by Consultant in connection with the services
to the Company in a matter of material importance to the conduct of the
Company’s affairs which has a material adverse affect on the business of the
Company, or (ii) the conviction of Consultant for commission of a felony.  For
purposes of this subsection, no act or failure to act on the Consultant’s part
shall be considered “willful” unless done, or omitted to be done, by the
Consultant not in good faith and without reasonable belief that his action or
omission was in the best interest of the Company.  Termination of this Agreement
pursuant to this Section 10.4 shall be made by delivery to Consultant of a copy
of a resolution duly adopted by the affirmative vote of all of the members of
the Board of Directors called and held for such purpose (after 30 days prior
written notice to Consultant and reasonable opportunity for Consultant to be
heard before the Board of Directors prior to such vote), finding that in the
good faith business judgment of such Board of Directors, Consultant was guilty
of conduct set forth in any of clauses (i) through (ii) above and specifying the
particulars thereof.

 

11.                               Assignment:

 

This Agreement shall be binding upon and inure to the benefit of the heirs and
representatives of Consultant and the assigns and successors of Company, but
neither this Agreement nor any rights or obligations hereunder shall be
assignable or otherwise subject to hypothecation by Consultant (except by will
or by operation of the laws of intestate succession or by Consultant notifying
the Company that cash payment be made to an affiliated investment partnership in
which Consultant is a control person) or by Company, except that Company may
assign this Agreement to any successor (whether by merger, purchase or
otherwise) to all or substantially all of the stock, assets or businesses of
Company, if such successor expressly agrees to assume the obligations of Company
hereunder.

 

12.                               Change In Control:

 

12.1        Definition.             For purposes of this Agreement, a “Change in
Control” shall be deemed to have occurred if (i) there shall be consummated (A)
any consolidation or merger of the Company in which the Company is not the
continuing or surviving corporation or pursuant to which shares of the Company’s
Common Stock would be converted into cash, securities or other property, other
than a merger of the Company in which the holders of the Company’s Common Stock
immediately prior to the merger have substantially the same proportionate

 

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ownership of common stock of the surviving corporation immediately after the
merger, or (B) any sale, lease, exchange or other transfer (in one transaction
or a series of related transactions) of all or substantially all the assets of
the Company, or (ii) the stockholders of the Company shall approve any plan or
proposal for the liquidation or dissolution of the Company, or (iii) any person
(as such term is used in Sections 13(d) and 14(d)(2) of the Securities Exchange
Act of 1934 (the “Exchange Act”)), other than the Company or any Consultant
benefit plan sponsored by the Company, or such person on the Effective Date
hereof is a 20% or more beneficial owner, shall become the beneficial owner
(within the meaning of Rule 13d-3 under the Exchange Act) of securities of the
Company representing 20% or more of the combined voting power of the Company’s
then outstanding securities ordinarily (and apart from rights accruing in
special circumstances) having the right to vote in the election of directors, as
a result of a tender or exchange offer, open market purchases, privately
negotiated purchases or otherwise, or (iv) at any time during a period of two
consecutive years, individuals who at the beginning of such period, constituted
the Board of Directors of the Company shall cease for any reason to constitute
at least a majority thereof, unless the election or the nomination for election
by the Company’s stockholders of each new director during such two-year period
was approved by a vote of at least two-thirds of the directors then still in
office, who were directors at the beginning of such two-year period.

 

12.2        Rights and Obligations.          If a Change in Control of the
Company shall have occurred while the Consultant is director of the Company, the
Consultant shall be entitled to the payments provided in Section 10.1 of this
Agreement upon the subsequent termination of this Agreement by either the
Company, or the Consultant within two years of the date upon which the Change in
Control shall have occurred, unless such termination is a result of (i) the
Consultant’s death; (ii) the Consultant’s Disability; (iii) the Consultant’s
Retirement; or (iv) the Consultant’s termination for Cause.

 

7.                                      Indemnification:

 

Consultant, as such and as a Director of the Company, shall be indemnified by
the Company against all liability incurred by the Consultant in connection with
any proceeding, including, but not necessarily limited to, the amount of any
judgment obtained against Consultant, the amount of any settlement entered into
by the Consultant and any claimant with the approval of the Company, attorneys’
fees, actually and necessarily incurred by him in connection with the defense of
any action, suit, investigation or proceeding or similar legal activity,
regardless of whether criminal, civil, administrative or investigative in nature
(“Claim”), to which he is made a party or is otherwise subject to, by reason of
his being or having been a director, officer, agent or employee of the Company,
to the full extent permitted by applicable law and the Certificate of
Incorporation of the Company.  Such right of indemnification will not be deemed
exclusive of any other rights to which Consultant may be entitled

 

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under Company’s Certificate of Incorporation or By-laws, as in effect from time
to time, any agreement or otherwise.

 

14.          Miscellaneous:

 

(a)           This Agreement between the Company and Consultant constitutes the
entire agreement and understanding of the parties hereto, and supersedes any and
all previous agreements and understandings, whether oral or written, between the
parties with respect to the matters set forth herein.

 

(b)           Any notice or communication permitted or required hereunder shall
be in writing and shall be deemed sufficiently given if hand-delivered or sent
(i) postage prepaid by registered mail, return receipt requested, or (ii) by
facsimile, to the respective parties as set forth below, or to such other
address as either party may notify the other in writing.

 

If to the Company, to:

 

Synergy Pharmaceuticals, Inc.

 

 

420 Lexington Avenue, Suite 1609

 

 

New York, New York 10170

 

 

Attention: Gary S. Jacob, CEO

 

 

 

If to Consultant, to:

 

Gabriele M. Cerrone

 

 

Via Sant’Andrea 18

 

 

Milano Italy 20121

 

(c)           This Agreement may be executed in any number of counterparts, each
of whom together shall constitute one and the same original document.

 

(d)           This Agreement may not be changed orally, but only by an agreement
in writing signed by the party against whom any waiver, change, amendment,
modification or discharge is sought.

 

(e)           The invalidity of all or any part of any provision of this
Agreement shall not render invalid the remainder of this Agreement or the
remainder of such provision.  If any provision of this Agreement is so broad as
to be unenforceable, such provision shall be interpreted to be only so broad as
is enforceable.

 

(f)            This Agreement shall be governed by and construed in accordance
with the law of the State of New York without giving effect to the principles of
conflicts of law thereof.  The parties hereto each hereby submits herself or
itself for the sole purpose of this Agreement and any controversy arising
hereunder to the exclusive jurisdiction of the state courts in the State of New
York.

 

(g)           Any amounts due hereunder to Consultant which remain unpaid after
their due date, shall bear interest from the due date until paid at a rate of
the prime rate (in effect on the date thereof for Citibank).

 

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(h)           The Company’s obligations to make payments under Section 10 and 12
shall survive termination or expiration of this Agreement.

 

(i)            Consultant shall not be required to mitigate damages or the
amount of any payment provided for under this Agreement by seeking other
employment or otherwise after the termination of this Agreement.

 

IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be duly
executed, as of the date first above written.

 

 

 

CONSULTANT

 

 

 

 

 

/s/ Gabriele M. Cerrone

 

Gabriele M. Cerrone

 

 

 

 

 

SYNERGY PHARMACEUTICALS INC.

 

 

 

 

 

 

By:

/s/ Gary S. Jacob

 

 

Name:

Gary S. Jacob

 

 

Title:

President and

 

 

 

CEO

 

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