Exhibit 10.1

Eiger BioPharmaceuticals, Inc.

Non-Employee Director Compensation Policy

Adopted by the board: September 3, 2013

Amended: April 12, 2017

Each member of the Board of Directors (the “Board”) who is not also serving as
an employee of Eiger BioPharmaceuticals, Inc. (“Eiger”) or any of its
subsidiaries (each such member, an “Eligible Director”) will receive the
compensation described in this Non-Employee Director Compensation Policy for his
or her Board service on and following the date of the underwriting agreement
between Eiger and the underwriters managing the initial public offering of the
common stock of Eiger (the “Common Stock”), pursuant to which the Common Stock
is priced in such initial public offering (the “Effective Date”).  This policy
is effective as of the Effective Date and may be amended at any time in the sole
discretion of the Board or the Compensation Committee of the Board.

Annual Cash Compensation

The annual cash compensation amount set forth below is payable in equal
quarterly installments, payable in arrears on the last day of each fiscal
quarter in which the service occurred. If an Eligible Director joins the Board
or a committee of the Board at a time other than effective as of the first day
of a fiscal quarter, each annual retainer set forth below will be pro-rated
based on days served in the applicable fiscal year, with the pro-rated amount
paid for the first fiscal quarter in which the Eligible Director provides the
service, and regular full quarterly payments thereafter. All annual cash fees
are vested upon payment.

1.

Annual Board Service Retainer:

 

a.

All Eligible Directors: $40,000

 

b.

Chairman of the Board Service Retainer (in addition to Eligible Director Service
Retainer): $30,000

2.Annual Committee Member Service Retainer:

 

a.

Member of the Audit Committee: $7,500

 

b.

Member of the Compensation Committee: $5,000

 

c.

Member of the Nominating & Governance Committee: $3,750

3.

Annual Committee Chair Service Retainer (in addition to Committee Member Service
Retainer):

 

a.

Chairman of the Audit Committee: $15,000

 

b.

Chairman of the Compensation Committee: $10,000

 

c.

Chairman of the Nominating & Governance Committee: $7,500

1.

 

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Equity Compensation

The equity compensation set forth below will be granted under the Eiger
Corporation 2013 Equity Incentive Plan (the “Plan”), subject to the Eiger
stockholders’ approval of the Plan. All stock options granted under this policy
will be nonstatutory stock options, with an exercise price per share equal to
100% of the Fair Market Value (as defined in the Plan) of the underlying Common
Stock on the date of grant, and a term of ten years from the date of grant
(subject to earlier termination in connection with a termination of service as
provided in the Plan, provided that upon a termination of service other than for
cause, the post-termination exercise period will be three years from the date of
termination, subject to the original term of the option).

1.Initial Grant: On the date of the Eligible Director’s initial election to the
Board, for each Eligible Director who is first elected to the Board following
the Effective Date (or, if such date is not a market trading day, the first
market trading day thereafter), the Eligible Director will be automatically, and
without further action by the Board or Compensation Committee of the Board,
granted a stock option for 25,000 shares (the “Initial Grant”).  The shares
subject to each Initial Grant will vest in equal monthly installments over a
three year period such that the option is fully vested on the third anniversary
of the date of grant, subject to the Eligible Director’s Continuous Service (as
defined in the Plan) through each such vesting date and will vest in full upon a
Change in Control (as defined in the Plan).

2.Annual Grant: At the Compensation Committee meeting held in January,  February
or March of each year for the purpose of granting executives annual equity
incentive awards following the Effective Date or, if a Compensation Committee
meeting is not held by the end of February of any year, on the last trading date
in March of such year following the Effective Date, for each Eligible Director
who continues to serve as a non-employee member of the Board (or who is first
elected to the Board at such annual stockholder meeting), the Eligible Director
will be automatically, and without further action by the Board or Compensation
Committee of the Board, granted a stock option for 10,000 shares (the “Annual
Grant”). In addition, each Eligible Director who is first elected to the Board
following the Effective Date and other than at an annual stockholder meeting
will be automatically, and without further action by the Board or Compensation
Committee of the Board, granted an Annual Grant, pro rated for the number of
months remaining until the next annual stockholder meeting. The shares subject
to the Annual Grant will vest over one year in twelve equal monthly installments
subject to the Eligible Director’s Continuous Service (as defined in the Plan)
through such vesting date and will vest in full upon a Change in Control (as
defined in the Plan).

3.Eligible Directors serving on the Board on the Effective Date:  Unless
otherwise provided by the Board, each Eligible Director who is serving on the
Board on the Effective Date will be granted a stock option for 10,000 shares
that will vest over one year in twelve equal monthly installments subject to the
Eligible Director’s Continuous Service (as defined in the Plan) through such
vesting date.

2.

 

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