Exhibit 10.17(b)

[***] Certain information in this document has been excluded pursuant to
Regulation S-K, Item 601(b)(10). Such excluded information is not material and
would likely cause competitive harm to the registrant if publicly disclosed.

AMENDING AGREEMENT
Nerlynx License Agreement

THIS AGREEMENT made effective as of the 18th day of December, 2019 (the
“Amending Agreement”)

By and Between

PUMA BIOTECHNOLOGY, INC., a corporation incorporated under the laws of Delaware
(“Licensor”);

and:

KNIGHT THERAPEUTICS INC., a corporation incorporated under the laws of Canada
(“Knight”).

(Licensor and Knight are hereinafter individually referred to as a “Party” and
collectively as the “Parties”)

WHEREAS Licensor and Knight entered into a License Agreement dated January 9,
2019 (the “Original Agreement”);

WHEREAS the Parties wish to clarify certain aspects of the Original Agreement.

NOW THEREFORE, THE PARTIES HEREBY AGREE AS FOLLOWS:

1.

The Original Agreement is amended by adding the following as Section 6.15
thereof:

 

“6.15.

Royalty Allocation. The Parties confirm and agree that with respect to any and
all royalties paid or payable by Knight to Licensor hereunder, [***] of any such
amount shall be for and in respect of the licenses as granted hereunder to the
Licensor’s Patents and Know‑How and the balance of [***] shall be for and in
respect to the licenses granted hereunder for the Licensor Marks, provided,
however, such allocation shall in no event increase, reduce or otherwise change
any of the royalty amounts payable by Knight to Licensor in the aggregate in
accordance with the terms of this Agreement.”

2.

This Amending Agreement shall enure to the benefit of and be binding upon the
Parties and their respective successors and legal personal representatives.

3.

This Amending Agreement may be executed by the Parties in separate counterparts
each of which when so executed and delivered shall be an original, but all such
counterparts shall together constitute one and the same instrument. The Parties
agree that this Amending Agreement may be transmitted by facsimile and that the
reproduction of signatures by facsimile will be treated as binding as if
originals.

 

--------------------------------------------------------------------------------

 

4.

All other terms of the Original Agreement shall remain in full force and effect
unamended and are hereby ratified by the Parties hereto in all respects.

5.

This Agreement all disputes arising out of or relating to this Agreement, or the
performance, enforcement, breach or termination hereof or thereof, and any
remedies relating thereto, shall be construed, governed by and interpreted in
accordance with the laws of New York.

IN WITNESS WHEREOF the Parties hereto have executed this Amending Agreement as
of the day and year first above written.

 

PUMA BIOTECHNOLOGY, INC.

 

KNIGHT THERAPEUTICS INC.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Per:

 

/s/ Maximo F. Nougues

 

Per:

 

/s/ Amal Khouri

Name:

 

Maximo F. Nougues

 

Name:

 

Amal Khouri

Title:

 

Chief Financial Officer

 

Title:

 

VP Business Development