Exhibit 10.6

ASSIGNMENT OF PATENTS AND TRADEMARKS

WHEREAS, QLT USA, Inc., a Delaware corporation, with offices at 2579 Midpoint
Drive, Fort Collins, CO 80525 (“ASSIGNOR”), owns certain patent applications
and/or registrations, as listed in Exhibit A attached hereto and incorporated
herein by this reference (“PATENTS”), and trademarks, including applications and
registrations, as listed on Exhibit B attached hereto and incorporated herein by
this reference (the “MARKS”); and

WHREAS, Arius Two, Inc., a Delaware corporation, with offices at 2501 Aerial
Center parkway, Suite 205, Morrisville, North Carolina 27560 (“ASSIGNEE”),
desires to acquire all of the right, title and interest in, to and under the
PATENTS and to the MARKS in accordance with the terms of that certain
Intellectual Property Assignment Agreement dated August 2, 2006 (the “Transfer
Agreement”);

NOW, THEREFORE, in consideration of the sum of One Dollar ($1.00) and other good
and valuable consideration paid by ASSIGNEE to ASSIGNOR, the receipt and
sufficiency of which hereby is acknowledged, ASSIGNOR does hereby: (1) sell,
assign, transfer and convey unto ASSIGNEE all right, title and interest in and
to the PATENTS, including all divisions, continuations, continuations-in-part,
reexaminations, substitutions, reissues, extensions and renewals of the
applications and registrations for the PATENTS (and the right to apply for any
of the foregoing); all rights to causes of action and remedies related thereto
(including, without limitation, the right to sue for past, present or future
infringement, misappropriation or violation of rights related to the foregoing);
and any and all other rights and interests arising out of, in connection with or
in relation to the PATENTS, and (2) transfer, convey and assign to ASSIGNEE all
right, title and interest throughout the world (excluding the United States of
America, its territories and possessions (including the Commonwealth of Puerto
Rico)) in and to the MARKS, together with all goodwill associated therewith,
effective upon ASSIGNOR’S receipt of all payments due hereunder.

In the event of any conflict or inconsistency between the terms of the Transfer
Agreement and the terms hereof, the terms of the Transfer Agreement shall
govern.

IN WITNESS WHEREOF, ASSIGNOR has caused this Assignment to be duly executed by
an authorized officer on this 2nd day of August, 2006.

 

By:  

/s/ Michael R. Duncan

Name:   Michael R. Duncan, President

--------------------------------------------------------------------------------

EXHIBIT A

COMPANY PATENT RIGHTS

NON-US

 

Filing Date

  

Appl. Ser./Pub. Nos.

   Country/Status   

Title

   Priority Oct 16 1997   

PCT/US97/18605

WO 1998/17251 (PCT of US 08/734,519)

 

(334WO1)

   PCT – completed    Pharmaceutical Carrier Device Suitable for Delivery of
Pharmaceutical Compounds to Mucosal Surfaces    US 08/734,519
(Oct. 18, 1996) Oct 16, 1997   

AU 97/47574

(Nat’l stage of

PCT/US97/18605)

 

(334AU1)

   AUPN: 729516
Issued: May 17, 2001
Expires: Oct 16, 2017    Pharmaceutical Carrier Device …Mucosal Surfaces    US
08/734,519
(Oct. 18, 1996) Apr 26, 2001   

AU 2001/38924

(DIV of AU 97/47574)

 

(334UA2)

   AUPN: 769500
Issued: May 13, 2004
Expires: Oct 16, 2017    Pharmaceutical Carrier Device …Mucosal Surfaces    US
08/734,519
(Oct. 18, 1996) Apr 26, 2001   

CA 2268187

(Nat’l stage of

PCT/US97/1/18605)

 

(334CA1)

   Canada - pending    Pharmaceutical Carrier Device …Mucosal Surfaces    US
08/734,519
(Oct. 18, 1996) Apr 26, 1997   

EP97910117.7

(Nat’l stage of

PCT/US97/1/18605)

 

(334EP1)

   EPPN: 0973497
Issued: Dec 11, 2002
Expires: Oct 16, 2017

 

Also issued in
Austria, Belgium,
Denmark, France,
Germany, Greece,
Ireland, Italy,
Netherlands, Spain,
Sweden, Switzerland,
and United Kingdom

   Pharmaceutical Carrier Device …Mucosal Surfaces    US 08/734,519
(Oct. 18, 1996) Oct 16, 1997   

JP 10-519467

(Nat’l stage of

PCT/US97/1/18605)

 

(334EP1)

   Japan – pending    Pharmaceutical Carrier Device …Mucosal Surfaces    US
08/734,519
(Oct. 18, 1996) Oct 16, 1997   

JP 200518632

(DIV of JP 10-519467)

 

Pubn No. 2005-281322 Published Oct 13, 2005 (334JP2)

   Japan - pending    Pharmaceutical Carrier Device …Mucosal Surfaces    US
08/734,519
(Oct. 18, 1996)

--------------------------------------------------------------------------------

Filing Date

  

Appl. Ser./Pub. Nos.

   Country/Status   

Title

   Priority Apr 29, 1999   

PCT/US99/09378 WO 99/55312 (PCT of US 09/069,703)

 

(335WO1)

   PCT – completed    Pharmaceutical Carrier Device …Mucosal Surfaces   
US 08/734,519
(Oct 18, 1996)
US 09/069,703
(Apr. 29, 1998) Apr 29, 1999   

AU 99/39678

(Nat’l stage of PCT/US99/09378)

 

(335AU1)

   AUPN: 746339
Issued: Aug 1,
2002
Expires: Apr. 29,
2019    Pharmaceutical Carrier Device …Mucosal Surfaces    US 08/734,519
(Oct 18, 1996)
US 09/069,703
(Apr. 29, 1998) Apr 29, 1999   

CA 2,329,128

(Nat’l stage of PCT/US99/09378)

 

(335CA1)

   Canada – pending    Pharmaceutical Carrier Device …Mucosal Surfaces    US
08/734,519
(Oct 18, 1996)
US 09/069,703
(Apr. 29, 1998) Apr 29, 1999   

EP 99922753.1

(Nat’l stage of PCT/US99/09378)

 

(335EP1)

   EP 1079813
Issued: Feb 9, 2005
Expires: Apr.
29, 2019

 

Also issued in
Austria, Belgium,
Denmark, Finland,
France, Germany,
Greece, Ireland,
Italy, Luxembourg,
Netherlands,
Portugal, Spain,
Sweden,
Switzerland, and
United Kingdom

   Pharmaceutical Carrier Device …Mucosal Surfaces    US 08/734,519
(Oct 18, 1996)
US 09/069,703
(Apr. 29, 1998) Apr 29, 1999   

JP 2000545511

(Nat’l stage of PCT/US99/09378)

 

(335JP1)

   Japan – pending    Pharmaceutical Carrier Device …Mucosal Surfaces    US
08/734,519
(Oct 18, 1996)
US 09/069,703
(Apr. 29, 1998) Apr 29, 1999   

JP 2005233505

(DIV of JP 2000545511)

 

(335JP2)

   Japan – pending    Pharmaceutical Carrier Device …Mucosal Surfaces    US
08/734,519
(Oct 18, 1996)
US 09/069,703
(Apr. 29, 1998)

--------------------------------------------------------------------------------

Filing Date

  

Appl. Ser./Pub. Nos.

   Country/Status   

Title

   Priority Apr 11, 2003   

PCT/US 03/11313

WO 03/086345

(PCT of US 10/121,430)

 

(237WO1)

   PCT – completed    Process for Loading a Drug Delivery Device   
US 10/121,430
(Apr. 11, 2002) Aug 16, 2004   

PCT/US2004/026531

WO 2005/016321

(PCT of US 60/495,356)

 

(309WO1)

   PCT – completed    Adhesive Bioerodible Transmucosal Drug Delivery System   
US 60/495,356
(Aug 15, 2003) Aug 16, 2004   

AU 2004/264974

(Nat’l stage of

PCT/US2004/026531)

 

(309AU1)

   Australia - pending    Adhesive Bioerodible Transmucosal Drug Delivery System
   US 60/495,356
(Aug 15, 2003) Aug 16, 2004   

CA 2,535,846

(Nat’l stage of

PCT/US2004/026531)

 

(309CA1)

   Canada - pending    Adhesive Bioerodible Transmucosal Drug Delivery System   
US 60/495,356
(Aug 15, 2003) Aug 16, 2004   

EP 04781250.8

(Nat’l stage of

PCT/US2004/026531)

Publ EP1660056

Published May 31, 2006

 

(309EP1)

   EP - pending    Adhesive Bioerodible Transmucosal Drug Delivery System   
US 60/495,356
(Aug 15, 2003) Aug 16, 2004   

JP

(Nat’l stage of

PCT/US2004/026531)

 

(309JP1)

   JP - pending    Adhesive Bioerodible Transmucosal Drug Delivery System   
US 60/495,356
(Aug 15, 2003) Aug 16, 2004   

MX PA/a/2006/001776

(Nat’l stage of

PCT/US2004/026531)

 

(309MX1)

   MX - pending    Adhesive Bioerodible Transmucosal Drug Delivery System   
US 60/495,356
(Aug 15, 2003)

--------------------------------------------------------------------------------

SCHEDULE 1.22

COMPANY TRADEMARK RIGHTS

BEMA

 

Country

   Application No. /
Filed Date    Registration No. /
Registration    Expiry /Renewal
Date   

Description/Comments

   Priority Australia    1028272 Nov
4, 2004    1028272
Apr 11, 2005    Nov 4, 2014
Nov 4, 2014    Cl. 05 - Polymer Film, namely, adhesive bandages for topical
application of pharmaceuticals;
Cl. 10 - Polymer film for use as an applicator for pharmaceuticals   
US 78/424675
May 25, 2004 Japan    2004-107883
Nov 25, 2004    pending       CL 05, CL 10 - Polymer film, namely, adhesive
bandages for topical application of pharmaceuticals    US 78/424675
May 25, 2004 European Community OHIM    004097416
Nov 4, 2004    pending       Cl. 05 - Polymer Film, namely, adhesive bandages
for topical application of pharmaceuticals;
Cl. 10 - Polymer film for use as an applicator for pharmaceuticals    US
78/424675
May 25, 2004