--------------------------------------------------------------------------------

EXHIBIT 10.21

THIS AGREEMENT IS DATED 31 JULY 2006

BETWEEN

(1) Alliance Boots plc whose registered office is at Sedley Place, 4th Floor,
361 Oxford Street, London, W1C 2JL;

(2) Alliance UniChem Plc whose registered office is at 2 The Heights,
Brooklands, Weybridge, Surrey, KT13 0NY; and

(3) ORNELLA BARRA of 2 The Heights, Brooklands, Weybridge, Surrey, KT13 0NY
(“The Executive”).

WHEREAS

(A) The Executive is employed by Alliance UniChem Plc under the terms of a
Service Agreement dated 10 December 2002 (“the Service Agreement”).

(B) On 31 July 2006 the merger of Boots Group PLC and Alliance UniChem Plc was
completed and Boots Group PLC changed its name to Alliance Boots plc.

IT IS AGREED BETWEEN THE PARTIES AS FOLLOWS

1. On 31 July 2006 the Executive’s Service Agreement with Alliance UniChem Plc
terminated by mutual consent.

2. With immediate effect thereafter a New Service Agreement commenced between
the Executive and Alliance Boots plc (“the New Service Agreement”). The New
Service Agreement was agreed to be on identical terms to the Service Agreement
save for the removal of the restriction under clause 17.1.1 in relation to
Boots. The Executive’s continuity of employment is preserved and all references
to Alliance UniChem Plc contained in the Service Agreement shall be construed as
references to Alliance Boots plc in the New Service Agreement.

IN WITNESS WHEREOF THIS AGREEMENT HAS BEEN SIGNED BY OR ON BEHALF OF THE
PARTIES.

 /s/ Marco Pagni
 
For Alliance Boots plc
     
 /s/ Marco Pagni
 
For Alliance UniChem Plc
     
 /s/ Ornella Barra
 
ORNELLA BARRA
 

 

--------------------------------------------------------------------------------