Task: Question Answering
Input (English): Context: Tread Marks is a 3D, third-person perspective, multiplayer-focused tank combat and racing computer game developed by Longbow Digital Arts. The game won the 2000 Independent Games Festival grand prize, later renamed to the Seumas McNally award in honor of the game's lead programmer who died on 21 March 2000, after receiving the award.
Gameplay.
The game features three gameplay modes:, The Amiga is a family of personal computers sold by Commodore in the 1980s and 1990s. Based on the Motorola 68000 family of microprocessors, the machine has a custom chipset with graphics and sound capabilities that were unprecedented for the price, and a pre-emptive multitasking operating system called AmigaOS. The Amiga provided a significant upgrade from earlier 8-bit home computers, including Commodore's own C64., The Independent Games Festival (IGF) is an annual festival at the Game Developers Conference, the largest annual gathering of the indie video game industry. It was founded in 1998 to assist and inspire innovation in video game development and to recognize the best independent video game developers. IGF was founded to create for the independent game community the same benefit the Sundance Film Festival has brought to the independent film community, and is produced by the CMP Game Group, producers of the Game Developers Conference, Game Developer magazine, and Gamasutra.com., The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS). AIDS is a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells., Fever, also known as pyrexia and febrile response, is defined as having a temperature above the normal range due to an increase in the body's temperature set-point. There is not a single agreed-upon upper limit for normal temperature with sources using values between . The increase in set-point triggers increased muscle contraction and causes a feeling of cold. This results in greater heat production and efforts to conserve heat. When the set-point temperature returns to normal, a person feels hot, becomes flushed, and may begin to sweat. Rarely a fever may trigger a febrile seizure. This is more common in young children. Fevers do not typically go higher than .
A fever can be caused by many medical conditions ranging from the not serious to potentially serious. This includes viral, bacterial and parasitic infections such as the common cold, urinary tract infections, meningitis, malaria and appendicitis among others. Non-infectious causes include vasculitis, deep vein thrombosis, side effects of medication, and cancer among others. It differs from hyperthermia, in that hyperthermia is an increase in body temperature over the temperature set-point, due to either too much heat production or not enough heat loss.
Treatment to reduce fever is generally not required. Treatment of associated pain and inflammation, however, may be useful and help a person rest. Medications such as ibuprofen or paracetamol may help with this as well as lower temperature. Measures such as putting a cool damp cloth on the forehead and having a slightly warm bath are not useful and may simply make a person more uncomfortable. Children younger than three months require medical attention, as might people with serious medical problems such as a compromised immune system or people with other symptoms. Hyperthermia does require treatment.
Fever is one of the most common medical signs. It is part of about 30% of healthcare visits by children and occurs in up to 75% of adults who are seriously sick. While fever is a useful defense mechanism, treating fever does not appear to worsen outcomes. Fever is viewed with greater concern by parents and healthcare professionals than it usually deserves, a phenomenon known as fever phobia., Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV). Following initial infection, a person may not notice any symptoms or may experience a brief period of influenza-like illness. Typically, this is followed by a prolonged period with no symptoms. As the infection progresses, it interferes more with the immune system, increasing the risk of common infections like tuberculosis, as well as other opportunistic infections, and tumors that rarely affect people who have working immune systems. These late symptoms of infection are referred to as AIDS. This stage is often also associated with weight loss.
HIV is spread primarily by unprotected sex (including anal and oral sex), contaminated blood transfusions, hypodermic needles, and from mother to child during pregnancy, delivery, or breastfeeding. Some bodily fluids, such as saliva and tears, do not transmit HIV. Methods of prevention include safe sex, needle exchange programs, treating those who are infected, and male circumcision. Disease in a baby can often be prevented by giving both the mother and child antiretroviral medication. There is no cure or vaccine; however, antiretroviral treatment can slow the course of the disease and may lead to a near-normal life expectancy. Treatment is recommended as soon as the diagnosis is made. Without treatment, the average survival time after infection is 11 years.
In 2015 about 36.7 million people were living with HIV and it resulted in 1.1 million deaths. Most of those infected live in sub-Saharan Africa. Between its discovery and 2014 AIDS has caused an estimated 39 million deaths worldwide. HIV/AIDS is considered a pandemica disease outbreak which is present over a large area and is actively spreading. HIV is believed to have originated in west-central Africa during the late 19th or early 20th century. AIDS was first recognized by the United States Centers for Disease Control and Prevention (CDC) in 1981 and its causeHIV infectionwas identified in the early part of the decade.
HIV/AIDS has had a great impact on society, both as an illness and as a source of discrimination. The disease also has large economic impacts. There are many misconceptions about HIV/AIDS such as the belief that it can be transmitted by casual non-sexual contact. The disease has become subject to many controversies involving religion including the Catholic Church's decision not to support condom use as prevention. It has attracted international medical and political attention as well as large-scale funding since it was identified in the 1980s., Lymphoma is a group of blood cell tumors that develop from lymphocytes (a type of white blood cell). The name often refers to just the cancerous ones rather than all such tumors. Signs and symptoms may include enlarged lymph nodes, fever, drenching sweats, unintended weight loss, itching, and constantly feeling tired. The enlarged lymph nodes are usually painless. The sweats are most common at night.
There are dozens of subtypes of lymphomas. The two main categories of lymphomas are Hodgkin's lymphomas (HL) and the non-Hodgkin lymphomas (NHL). The World Health Organization (WHO) includes two other categories as types of lymphoma: multiple myeloma and immunoproliferative diseases. About 90% of lymphomas are non-Hodgkin lymphomas. Lymphomas and leukemias are a part of the broader group of tumors of the hematopoietic and lymphoid tissues.
Risk factors for Hodgkin lymphoma include infection with EpsteinBarr virus and a history of the disease in the family. Risk factors for common types of non-Hodgkin lymphomas include autoimmune diseases, HIV/AIDS, infection with human T-lymphotropic virus, immunosuppressant medications, and some pesticides. Eating large amounts of red meat and tobacco smoking may also increase the risk. Diagnosis, if enlarged lymph nodes are present, is usually by lymph node biopsy. Blood, urine, and bone marrow testing may also be useful in the diagnosis. Medical imaging may then be done to determine if and where the cancer has spread. Lymphoma most often spreads to the lungs, liver, and/or brain.
Treatment may involve one or more of the following: chemotherapy, radiation therapy, targeted therapy, and surgery. In some non-Hodgkin lymphomas, an increased amount of protein produced by the lymphoma cells causes the blood to become so thick that plasmapheresis is performed to remove the protein. Watchful waiting may be appropriate for certain types. The outcome depends on the subtype with some being curable and treatment prolonging survival in most. The five-year survival rate in the United States for all Hodgkin lymphoma subtypes is 85%, while that for non-Hodgkin lymphomas is 69%. Worldwide, lymphomas developed in 566,000 people in 2012 and caused 305,000 deaths. They make up 34% of all cancers, making them as a group the seventh-most common form. In children, they are the third-most common cancer. They occur more often in the developed world than the developing world., Thomas Hodgkin (17 August 1798  5 April 1866) was a British physician, considered one of the most prominent pathologists of his time and a pioneer in preventive medicine. He is now best known for the first account of Hodgkin's disease, a form of lymphoma and blood disease, in 1832. Hodgkin's work marked the beginning of times when a pathologist was actively involved in the clinical process. He was a contemporary of Thomas Addison and Richard Bright at Guy's Hospital., DX-Ball 2 is a brick buster game for Microsoft Windows, developed by Longbow Games. As a follow up to "DX-Ball" by Michael P. Welch, the sequel is foremost remarked by the introduction of its 16-bit high-colour engine, presenting textured bricks and background graphics in vivid colours. The game also features two new Power-Ups, an easy to play "Kid-Mode", and a hotseat multiplayer mode, alongside an original soundtrack by SideWinder. "DX-Ball 2" also introduces the feature of board-set selection, allowing the player to select between different sets of boards to play. The free demo thereby comes packed with a total of 24 boards divided into 6 board-sets of 4 boards search. Additional board packs can then be installed for more boards, whereas "Board Pack 1" will expand the demo board-sets to 25 boards each, for a total of 150 boards. While a total of five board packs were released for the game, "DX-Ball 2" was eventually succeeded by "Rival Ball" in 2001., DX-Ball (stylized as DX  BLL, sometimes also written as DXBALL) is a freeware computer game for the PC first released in 1996 by Michael P. Welch and Seumas McNally. The game, originally based on an earlier series of Amiga games known as MegaBall, is patterned after classic ball-and-paddle arcade games such as "Breakout" and "Arkanoid". A level editor was also made available as well., Seumas McNally ( February 10 , 1979 -- March 21 , 2000 ) , was a computer game programmer , the founder , president and lead programmer of independent game development company , Longbow Digital Arts . Being credited for graphic design in the cult classic computer game DX - Ball , he was the founder of its sequel , DX - Ball 2 , and the 2000 Independent Games Festival Grand Prize winner , Tread Marks . McNally died of Hodgkin 's lymphoma shortly after winning the Grand Prize , which was subsequently named in his honor . His family members included Jim McNally ( father ) , Philippe McNally ( brother ) , and Wendy McNally ( mother ) ., The EpsteinBarr virus (EBV), also called human herpesvirus 4 (HHV-4), is one of eight known viruses in the herpes family, and is one of the most common viruses in humans., Microsoft Windows (or simply Windows) is a metafamily of graphical operating systems developed, marketed, and sold by Microsoft. It consists of several families of operating systems, each of which cater to a certain sector of the computing industry with the OS typically associated with IBM PC compatible architecture. Active Windows families include Windows NT, Windows Embedded and Windows Phone; these may encompass subfamilies, e.g. Windows Embedded Compact (Windows CE) or Windows Server. Defunct Windows families include Windows 9x; Windows 10 Mobile is an active product, unrelated to the defunct family Windows Mobile., The Sundance Film Festival, a program of the Sundance Institute, is an American film festival that takes place annually in Park City, Utah. With 46,660 attendees in 2016, it is the largest independent film festival in the United States. Held in January in Park City, Salt Lake City, and Ogden, as well as at the Sundance Resort, the festival is a showcase for new work from American and international independent filmmakers. The festival comprises competitive sections for American and international dramatic and documentary films, both feature films and short films, and a group of out-of-competition sections, including NEXT, New Frontier, Spotlight, Midnight, Premieres and Documentary Premieres. The 2017 Sundance Film Festival took place from January 19 to January 29, 2017., Hodgkin's lymphoma (HL) is a type of lymphoma, which is generally believed to result from white blood cells of the lymphocyte kind. Symptoms may include fever, night sweats, and weight loss. Often there will be non-painful enlarged lymph nodes in the neck, under the arm, or in the groin. Those affected may feel tired or be itchy.
About half of cases of Hodgkin's lymphoma are due to EpsteinBarr virus (EBV). Other risk factors include a family history of the condition and having HIV/AIDS. There are two major types of Hodgkin lymphoma: classical Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma. Diagnosis is by finding Hodgkin's cells such as multinucleated ReedSternberg cells (RS cells) in lymph nodes.
Hodgkin lymphoma may be treated with chemotherapy, radiation therapy, and stem cell transplant. The choice of treatment often depends on how advanced the cancer is and whether or not it has favorable features. In early disease a cure is often possible. The percentage of people who survive five years in the United States is 86%. For those under the age of 20 rates of survival are 97%. Radiation and some chemotherapy drugs, however, increase the risk of other cancers, heart disease, or lung disease over the subsequent decades.
In 2013 about 725,000 people had Hodgkin's lymphoma and 24,000 died. In the United States 0.2% of people are affected at some point in their life. The most common age of diagnosis is between 20 and 40 years old. It was named after the English physician Thomas Hodgkin, who first described the condition in 1832., Subject: seumas mcnally, Relation: date_of_death, Options: (A) 1 (B) 10 (C) 17 (D) 17 august 1798 (E) 1798 (F) 1832 (G) 1866 (H) 19 (I) 1979 (J) 1996 (K) 1998 (L) 2 (M) 20 (N) 2000 (O) 2013 (P) 2014 (Q) 2015 (R) 21 march 2000 (S) 24 (T) 30 (U) 36 (V) 4 (W) 46 (X) 69 (Y) 725 (Z) 75 ([) 8 (\) 9 (]) 90 (^) 97
Output (English): 21 march 2000