Task: Question Generation
Input (English): DNA must replicate (copy) itself so that each resulting cell after mitosis and cell division has the same DNA as the parent cell. All these cells, the parent cell and the two new daughter cells, are genetically identical. DNA replication occurs during the S phase (the Synthesis phase) of the cell cycle, before mitosis and cell division. The base pairing rules are crucial for the process of replication. DNA replication occurs when DNA is copied to form an identical molecule of DNA. The general steps involved in DNA replication are as follows: 1. The DNA helix unwinds like a zipper as the bonds between the base pairs are broken. The enzyme DNA Helicase is involved in breaking these bonds. 2. The two single strands of DNA then each serve as a template for a new stand to be created. Using DNA as a template means that on the new strand, the bases are placed in the correct order because of the base pairing rules. Recall that A and T are complementary bases, as are G and C. As a template strand is read, the new strand is created. If ATGCCA is on the "template strand," then TACGGT will be on the new DNA strand. The enzyme DNA Polymerase reads the template and builds the new strand of DNA. 3. The new set of nucleotides then join together to form a new strand of DNA. The process results in two DNA molecules, each with one old strand and one new strand of DNA. This process is known as semiconservative replication because one strand is conserved (kept the same) in each new DNA molecule ( Figure 1.1). DNA replication occurs when the DNA strands unzip, and the original strands of DNA serve as a template for new nucleotides to join and form a new strand.
Output (English): what is the first step in dna replication?