Task: Question Generation
Input (English): Both the FRAX and Garvan calculators are used to estimate absolute risk of fracture, but they sometimes produce different estimates. We sought to determine which patient characteristics contribute to these discrepancies.', 'Ten-year hip fracture risk was estimated for 122 women, using both FRAX and Garvan with bone mineral density (BMD).', 'Differences in estimates of hip fracture were assessed, both in absolute terms and with respect to a treatment threshold of 3%.', 'Garvan estimates were higher than FRAX estimates across the range of ages and BMDs studied. A history of falls or of multiple fractures increased risk calculated by Garvan 3-6-fold, but did not account for all differences between calculators. Discrepancies around a 3% treatment threshold occurred in 31/122 (25%). Women aged 70-74 years, and women with osteopenia were most likely to have discordant estimates. Most discordant estimates (29/31) had a Garvan estimate ≥ 3% and FRAX\u2009<3%. Falls, multiple fractures, ethnicity and a history of parental hip fracture contributed to some discordant estimates.
Output (English): Does reasons for discrepancies in hip fracture risk estimate using FRAX and Garvan calculators?