Task: Sentence Composition
Input (English): The story devotes its second paragraph to cost, including how that cost may differ depending on whether patients have insurance. Well done. This is a really close one. The story does a lot of things well here. It notes that, in one trial, there was no difference in the benefits between Xofluza and existing flu treatment drug oseltamivir (better known as Tamiflu). However, it does not actually quantify the benefits associated with Xofluza. Instead, the story states that it “may alleviate some symptoms and shorten the time patients feel sick.” We approve of the cautious language used throughout the story, but we like to see quantified benefits in instances where the information is available. In this case, an article published in the New England Journal of Medicine in September reported that Xofluza reduced the “time to alleviation of symptoms” by a mean of 25-38 hours, compared to placebo (the difference depended on the age group of the patient). Ergo, a not satisfactory rating here. The story addresses this issue head on, earning it a solid satisfactory rating from us. One point that would have made it even stronger would have been to note that the company selling Xofluza warns that pregnant women and nursing mothers may want to avoid the drug, as it is not known whether the drug may harm the fetus or if it would pass into breastmilk for nursing mothers. The story does a good job of describing the supporting evidence clearly and concisely. No disease mongering here. In fact, the story provides good context on the risks posed by influenza. The story incorporates input from two sources at the FDA, but the information appears to stem from an FDA statement. Information from pharmaceutical companies is clearly marked, but we really look for news stories to incorporate input from independent sources — beyond what may be available in a news release. The story addresses the similarities (and differences) to other drugs that address flu symptoms, particularly oseltamivir (Tamiflu). The story notes that Xofluza has received FDA approval. As noted above, the drugs similarities and differences to existing pharmaceutical treatment options was laid out clearly. The news peg here was FDA’s approval of the drug, which is also made clear. The work goes well beyond what you would find in any news release. We particularly applaud the story’s discussion of viruses developing resistance to antiviral drugs.
Output (English): F.D.A. Approves New Drug for Flu