Task: Text Categorization
Input (English): Question: In animals, where is most of the extracellular material components synthesized ?: 
 Options:  <0> In the smooth endoplasmic reticulum. <1> In the rough endoplasmic reticulum. <2> In the extracellular layer itself. <3> In the plasma membrane. <4> In the cytoplasm of the cell.
Output (English): chemistry