Task: Translation
Input (Czech): Amidové deriváty vzorce Ia, kde X je -NHCO- nebo -CONH-; m je 0 až 3; R.sup.1.n. je skupina jako hydroxy, halogen, trifluormethyl, kyanoskupina, merkaptoskupina, nitroskupina, aminoskupina, karboxyl a karbamoyl; n je 0 až 2; R.sup.2.n. je skupina, jako hydroxyl, halogen, trifluormethyl, kyanoskupina, merkaptoskupina, nitroskupina, aminoskupina a karboxyl; R.sup.3.n. je vodík, halogen C.sub.1-6.n.alkyl nebo C.sub.1-6.n.alkoxy; q je 0 až 4; a Q je skupina, jako aryl, aryloxy, arylC.sub.1-6.n.alkoxy, arylamino a N-C.sub.1-6.n.alkylarylamino; nebo jejich farmaceuticky prijatelné soli nebo in vivo štepitelné estery; zpusoby jejich prípravy; farmaceutické kompozice, které je obsahují a jejich použití pri lécení onemocnení nebo chorobných stavu zprostredkovaných cytokiny.
Output (English): The present invention relates to amide derivatives of the general formula Ia wherein X represents -NHCO- or -CONH-; m is 0 to 3; Re1 denotes a group such as hydroxy group, halo group, trifluoromethyl group, cyano group, mercapto group, nitro group, amino group, carboxy group and carbamoyl group; n is 0 to 2; Re2 represents a group such as hydroxy group, halo group, trifluoromethyl group, cyano group, mercapto group, nitro group, amino group and carboxy group; Re3 denotes hydrogen, halogen, alkyl containing 1 to 6 carbon atoms or alkoxy having 1 top 6 carbon atoms; q is 0 to 4; and Q represents a group such as aryl group, aryloxy group, arylalkoxy group containing 1 to 6 carbon atoms in the alkoxy moiety, arylamino group and N-alkyl-arylamino having 1 to 6 carbon atoms in the alkyl moiety; or pharmaceutically-acceptable salts or in-vivo-cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.