Task: Translation
Input (Spanish): The invention relates to 1-amino-phthalazine derivatives of general formula (I), wherein A, B = possibly substituted C1-4-alkylene; L = a simple bond or C1-2-alkylene, possibly substituted -CH=CH-, or -C=C- or cycloprop-1,2--diyl; R1 = possibly substituted aryl or heteroaryl; R2, R3 = H, C1-3-alkyl, C1-3-fluoralkyl or R2 et R3 forming together with a bearing them carbon atom, a cycloprop-1,1-diyl; R4 = H, C1-5-alkyl, C1-3-fluoralkyl, C3-6-cycloalkyl, C3-6-cycloalkyl-C1-3-alkylene, C1-3-alkyl-O-C1-3-alkylene, HO-C1-3-alkylene, C1-3-alkyl-X-C1-3-alkylene, wherein X = S, SO or S02; or R4 = RaRbN-C1-3-alkylene, aryl, aryl-C1-3-alkylene, aryl-O-, aryl-O-C1-3-alkylene, aryl-C1-3-alkylene-O-C1-3-alkylene, heteroaryl or heteroaryl-C1-3-alkylene; R5 = H, halogen, C1-5-alkyl, C1-3-fluoralkyl, C1-5-alkoxy, C1-3-fluoroalkoxy, HO-C1-3-alkylene, -CN, C1-3-alkyl-X-, wherein X = S, SO or SO2; or R5 = RaRbN-, RaRbN-C1-3-alkylene, aryl, aryl-C1-3-alkylene, aryl-O- or heteroaryl; R6 = H, halogen, C1-5-alkyl, C1-3-fluoralkyl, C1-5-alkoxy, C1-3-fluoroalkoxy, -CN, RaRbN-, RaRbN-C1-3-alkylene, aryl or heteroaryl ; R7 = H, halogen, C1-5-alkyl, C1-3-fluoralkyl, C1-5-alkoxy, C1-3-fluoroalkoxy, HO-C1-3--alkylene, -CN, C1-3-alkyl-X-, wherein X = S, SO or SO2; or R7, = RaRbN-, RaRbN-C1-3--alkylene, ReRbNC(O)-, C1-3-alkyl-C(O)-, aryl, aryl-0- or heteroaryl ; R8 = H, halogen, C1-5-alkyl, C1-5-alkoxy, C1-3-fluoroalkoxy ; in the form of base or acid additional salt and in the form of a hydrate or solvent.
Output (English): La invencion se refiere a derivados de 1-amino-ftalazina de formula general (I), donde A, B=alquileno C1-4 opcionalmente sustituido; L = un enlace sencillo o alquileno C1-2; -CH=CH-, opcionalmente sustituido, o -C=C- o cicloprop-1-,2-diilo; R1 = arilo o heteroarilo opcionalmente sustituido; R2, R3=H, alquilo C1-3, fluoroalquilo C1-3 o R2 y R3 junto con un atomo de carbono al que estan unidos forman un grupo cicloprop-1,1-diilo; R4 = H, alquilo C1-5, fluoroalquilo C1-3, cicloalquilo C3-6, cicloalquilo C3-6-alquileno C1-3, alquil C1-3-O-alquileno C1-3, HO-alquileno C1-3, alquil C1-3-X-alquileno C1-3, donde X = S, SO, o SO2; o R4 = RaRbN-alquileno C1-3, arilo, aril-alquileno C1-3, aril-O-, aril-O-alquileno C1-3, aril-alquilen C1-3-O-alquileno C1-3, heteroarilo o heteroaril-alquileno C1-3; R5 = H, halogeno, alquilo C1-5, fluoroalquilo C1-3, alcoxi C1-5, fluoroalcoxi C1-3, HO-alquileno C1-3, -CON, alquil C1-3-X-, donde X = S, SO o SO2; o R5 = RaRbN-alquileno C1-3, arilo, aril-alquileno C1-3, aril-O- o heteroarilo; R6 = H, halogeno, alquilo C1-5, fluoroalquilo C1-3, alcoxi C1-5, fluoroalcoxi C1-3, -CN, RaRbN-, RaRbN-alquileno C1-3, arilo o heteroarilo; R7 = H, halogeno, alquilo C1-5, fluoroalquilo C1-3, alcoxi C1-5, fluoroalcoxi C1-3, HO-alquileno C1-3, -CN, alquil C1-3-X-, donde X = S, SO o SO2; o R7 = RaRbN-, RaRbN-alquileno C1-3, ReRbNC(O)-, alquil C1-3-CO-, arilo, aril-O- o heteroarilo; R8 = H, halogeno, alquilo C1-5, alcoxi C1-5, fluoroalcoxi C1-3; en forma de base o sal de adicion de acido y en forma de hidrato o solvato.