Task: Translation
Input (Czech): Nitrilov  slou eniny obecn ho vzorce I, ve kter m Y, R.sup.5.n., R.sup.6.n. a R.sup.7.n. maj  °adu v²znam  uveden²ch podrobn  v popisn    sti a n znamen  0, 1, 2 nebo 3, p°edstavuj  inhibitory tumor necrosis faktoru alfa a fosfodiester zy. Tyto slou eniny je mo no pou  t k pot r n  kachexie, endotoxick ho Üoku, retrovirov  replikace, astma a z n tov²ch stav . Do rozsahu p°edm tn ho vyn lezu n le   uveden  slou eniny, farmaceutick² prost°edek obsahuj c  tyto slou eniny a pou it  t chto slou enin k v²Üe uveden²m · el m. Typickou slou eninou je 3-ftalimido-3-(3,4-dimethoxyfenyl)propionitril.\
Output (English): In the present invention there are disclosed nitrile compounds of the general formula I, in which Y, Re5, Re6 and Re7 have meaning indicated in detail in the descriptive section and n represents 0, 1, 2 or 3. These compounds are inhibitors of tumor necrosis factor alpha and phosphodiesterase and can be used to combat cachexia, endotoxic shock, retrovirus replication, asthma, and inflammatory conditions. The scope of the present invention covers the above indicated compounds, further a pharmaceutical composition containing them as well as use of these compounds to the aforementioned purposes. A typical embodiment is 3-phthalimido-3-(3,4-dimethoxyphenyl)propionitrile.