Task: Translation
Input (Czech): Opticky aktivn  pyrrolopyridazinov² deriv t obecn ho vzorce I nebo jeho farmaceuticky p°ijateln  s l, kde R.sup.1.n. je alkylov  skupina, R.sup.2.n. a R.sup.3.n. jsou navz jem nez visl  alkylov  skupiny, R.sup.4.n. je p° padn  substituovan  arylov  skupina, a A je imino skupina, atom kysl ku nebo atom s ry. Pyrrolopyridazinov  deriv ty obecn ho vzorce I nebo jejich farmaceuticky p°ijateln  soli vykazuj  vynikaj c  inhibici vylu ov n   alude n  kyseliny a vynikaj c  ochranu  alude n  sliznice, jako  i vynikaj c  antibakteri ln  · inek v  i Helicobacter pyroli. Jsou to · inn  l ky a p°edev  m jsou · inn  pro l  bu nebo prevenci v°edovit ho onemocn n .\
Output (English): An optically active pyrrolopyridazinone derivative of the general formula I or a pharmaceutically acceptable salt thereof, wherein R is 1. is an alkyl group; and R.sup.3.n. are not alkyl groups, R @ 4, R @ 4. is a substituted aryl group, and A is an imino group, an oxygen atom, or an atom. The pyrrolopyridazine derivatives of the general formula I or their pharmaceutically acceptable salts exhibit excellent inhibition of the excretion of the acid and excel in the protection of the mucosa as well as the antibacterial activity of Helicobacter pylori. They are useful and preventive or preventive in the disease. \ T