Task: Translation
Input (Czech): Zpusob prípravy 1-benzyl-4-(5,6-dimethoxyindan-1-on-2-yl)-methylpiperidinu (donepezil volná báze) vzorce I hydrogenací 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yliden]methylpyridinium bromidu vzorce IV za prítomnosti katalyzátoru platina na aktivním uhlí. 1-benzyl-4-(5,6-dimethoxyindan-1-on-2-yl)-methylpiperidin (donepezil volná báze) vzorce I se uvolní za vzniklého 1-benzyl-4-(5,6-dimethoxyindan-1-on-2-yl)-methylpiperidin hydrobromidu (donepezilhydrobromid) vzorce (V) pusobením vodného amoniaku.
Output (English): Process for preparing 1-benzyl-4- (5,6-dimethoxyindan-1-on-2-yl) methylpiperidine (donepezil free base) of formula I by hydrogenation of 1-benzyl-4 - [(5,6-dimethoxy-1-indanone) ) -2-ylidene] methylpyridinium bromide of formula IV in the presence of a platinum-on-charcoal catalyst. 1-Benzyl-4- (5,6-dimethoxyindan-1-on-2-yl) -methylpiperidine (donepezil free base) of Formula I is liberated to give 1-benzyl-4- (5,6-dimethoxyindan-1-one) -2-yl) -methylpiperidine hydrobromide (donepezil hydrobromide) of formula (V) by treatment with aqueous ammonia.