Task: Translation
Input (Czech): Deriv t 1,2,4-triazolo[4,3-b]pyrido[3,2-d]pyridazinu obecn ho vzorce I, kde znamen  R.sup.1.n. H, -(CH.sub.2.n.).sub.m.n.-Y, m je slo 0 a  4 a Y C.sub.1-6.n.alkyl, halogenC.sub.1-6.n.alkyl, C.sub.1-6.n.alkoxy, C.sub.1-6.n.alkoxykarbonyl, C.sub.3-7.n.cykloalkyl, norbornyl, nebo C.sub.7-12.n.fenylalkenyl nebo fenyl nebo pyridyl, p°i em  skupina Y je pop° pad  substituov na jedn m nebo n kolika halogeny, R.sup.2.n. fenyl, naftyl nebo thienyl, kter  jsou pop° pad  substituov ny jedn m nebo n kolika atomy halogenu, nebo skupinou C.sub.1-6.n.alkyl, C.sub.1-6.n.alkoxy, C.sub.3-6.n.cykloalkoxy, methylendioxy, NO.sub.2.n., di(C.sub.1-6.n.alkyl)amino a trifluormethyl a R.sup.3 .n. H, halogen nebo C.sub.1-6.n.alkyl, a jeho farmaceuticky p°ijateln  soli jsou jako to inhibitory fosfodiester zy 4 vhodn  pro v²robu farmaceutick²ch prost°edk  nap° klad k o et°ov n  z n tliv²ch a alergick²ch proces , jako je astma, nesteroid ln  protiz n tliv  gastrointestin ln  po kozen  vyvolan  drogami a atopick  dermatitis.\
Output (English): The 1,2,4-triazolo [4,3-b] pyrido [3,2-d] pyridazine derivative of the general formula I wherein R 1 is n. H, - (CH.sub.2.dbd), mn-Y, m is 0 and 4 and Y is C.sub.1-6nalkyl, haloC.sub.1-6n. alkyl, C.sub.1-6 .alkoxy, C.sub.1-6 .alkoxycarbonyl, C.sub.3-7.n.cycloalkyl, norbornyl, or C.sub.7-12.n phenylalkenyl or phenyl or pyridyl, wherein Y is a substituent on one or more halogens; phenyl, naphthyl or thienyl, which may be substituted by one or more halogen atoms, or by C.sub.1-6nalkyl, C.sub.1-6n.alkoxy, C.sub 3-6n.cycloalkoxy, methylenedioxy, NO.sub.2, di (C.sub.1-6n.alkyl) amino and trifluoromethyl and R.sup.3. H, halogen, or C 1-6 1-6 alkyl, and pharmaceutically acceptable salts thereof are useful as phosphodiester inhibitors for the production of pharmaceutical compositions including allergic and allergic processes, such as asthma, nonsteroidal anti-gastrointestinal infections after drug-induced dermatitis and atopic dermatitis.