Task: Translation
Input (Czech): Substituovaný disulfid obecného vzorce Q-Sp-SS-W, odvozený od sloučenin CH.sub.3.n.SSS-W, označovaných jako LL-E 33 288alfa.sub.1.n.-Br, LL-E 33 288alfa.sub.1.n.-I, LL-E 33 288alfa.sub.2.n.-Br, LL-E 33 288alfa.sub.2.n.-I, LL-E 33 288alfa.sub.3.n.-Br, LL-E 33 288alfa.sub.3.n.-I, LL-E 33 288alfa.sub.4.n.-Br, LL-E 33 288beta.sub.1.n.-Br, LL-E 33 288beta.sub.1.n.-I, LL-E 33 288beta.sub.2.n.-Br, LL-E 33 288beta.sub.2.n.-I, LL-E 33 288gama.sub.1.n.-Br, LL-E 33 288gama.sub.1.n.-I a LL-E 33 288delta.sub.1.n.-I, od jejich jod- nebo brom-pseudoglykonů a jejich dihydro- nebo N-acyl-homologů, od látek BBM-1675, FR-900 405 a FR-900 406 a od antibiotik PD 114 759, PD 115 028, CL-1577 A, CL-1577 B, CL-1577 D, CL-1577 E a CL-1724 nebo jejich N-acetylhomologů. Konjugáty tohoto disulfidu s nosičem a způsobů přípravy uvedeného disulfidu a konjugátu. Uvedené sloučeniny jsou disulfidové analogy protinádorových a antibakteriálních účinných látek známých pod společným označením LL-E 33 288.ŕ
Output (English): In the present invention, there is disclosed a substituted disulfide of the general formula Q-Sp-SS-W, derived from the compounds CHi3SSS-W, designated as LL-E 33 288{alpha}i1-Br, LL-E 33 288{alpha}i1-I, LL-E 33 288{alpha}i2-Br, LL-E 33 288{alpha}i2-I, LL-E 33 288{alpha}i3-Br, LL-E 33 288{alpha}i3-I, LL-E 33 288{alpha}i4-Br, LL-E 33 288{beta}i1-Br, LL-E 33 288{beta}i1-I, LL-E 33 288{beta}i2-Br, LL-E 33 288{beta}i2-I, LL-E 33 288{gamma}i1-Br, LL-E 33 288{gamma}i1-I and LL-E 33 288{delta}i1-I, further from their iodo- or bromo-pseudoglycones and their dihydro- or N-acyl-homologues, from the BBM-1675, FR-900 405 and FR-900 406 substances and from antibiotics PD 114 759, PD 115 028, CL-1577 A, CL-1577 B, CL-1577 D, CL-1577 E and CL-1724 or their N-acetyl homologues. Disclosed are also conjugates of the above-described disulfide with a carrier as well as processes for preparing both such disulfide and conjugate. The aforementioned compounds are disulfide analogs of antineoplastic and antibacterial active substance known under a common designation LL-E 33 288.