Task: Translation
Input (Spanish): Embodiments of the disclosure relate to selectively substituted quinoline compounds of formula (I) that act as antagonists or inhibitors for Toll -like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.
Output (English): Las modalidades de la descripción se refieren a compuestos de quinolina selectivamente sustituidos que actúan como antagonistas o inhibidores para receptores tipo Toll 7 y/u 8, y su uso en composiciones farmacéuticas efectivas para el tratamiento de lupus eritematoso sistémico (SLE) y nefritis lúpica.