Task: Question Generation
Input (English): Context: Is the proteolytic activity of pregnancy-associated plasma protein-A (PAPP-A) regulated by the stanniocalcins (STC1 and STC2) during human follicle maturation?
Answer: The STCs and PAPP-A show similar expression by immunohistochemistry in developing follicles, and regulation of PAPP-A proteolytic activity is suggested by the identification of inhibited protein complexes between PAPP-A and STC1 or STC2 in human follicular fluid (FF).
Output (English): Is the proteolytic activity of pregnancy-associated plasma protein-A potentially regulated by stanniocalcin-1 and -2 during human ovarian follicle development?