Task: Question Generation
Input (English): Context: It is known that large dogs who are fed lamb and rice diets are at increased risk to develop taurine-deficiency-induced dilated cardiomyopathy. Since dogs obligatorily conjugate bile acids (BA) with taurine, we determined whether rice bran (RB) or other fibers (cellulose; CL, beet pulp; BP) would affect BA excretion and/or the taurine status of dogs.', 'Eighteen medium/large mixed-breed dogs were given purified diets containing CL, BP, or RB for 12\xa0weeks. Taurine concentrations in plasma and whole blood were significantly decreased at week 12. The BP group, compared to the CL or RB groups, showed significantly lower taurine concentrations in plasma (6.5\u2009±\u20090.5 vs 20.4\u2009±\u20093.9 and 13.1\u2009±\u20092.0\xa0μmol/L, respectively, P\u2009<\u20090.01, mean\u2009±\u2009SEM) and in whole blood (79\u2009±\u200910 vs 143\u2009±\u200914 and 127\u2009±\u200914\xa0μmol/L, respectively, P\u2009<\u20090.01), lower apparent protein digestibility (81.9\u2009±\u20090.6 vs 88.8\u2009±\u20090.6 and 88.1\u2009±\u20091.2\xa0%, respectively, P\u2009<\u20090.01), and higher BA excretions (5.6\u2009±\u20090.1 vs 3.4\u2009±\u20090.5 and 3.4\u2009±\u20090.4\xa0μmol/g feces, respectively, P\u2009<\u20090.05) at week 12.
Answer: These results do not support the hypothesis that RB is likely to be a primary cause of lamb meal and rice diets, increasing the risk of taurine deficiency in large dogs. However these indicate that BP may contribute to a decrease taurine status in dogs by increasing excretion of fecal BA and decreasing protein digestibility, thus decreasing the bioavailability of sulfur amino acids, the precursors of taurine.
Output (English): Does dietary beet pulp decrease taurine status in dogs fed low protein diet?