Task: Translation
Input (Japanese): その決定は彼らが決定の「却下」に反対したように、申請を担当する機関の責任者と新薬研究所の所長によって承認されなかった。
Output (English): The decision was not signed off by the director of the office responsible for the application and the director of the Office of New Drugs, as they disagreed with the "reject" decision.