Task: Question Answering
Input (English): Chromosome mutations involve the deletion or duplication of many genes. The effects of chromosome mutations are often much greater than mutations within a single gene, because chromosome mutations  
 (A) can only occur at the time of fertilization. (B) can cause abnormal development of the offspring. (C) are always beneficial to the organism. (D) are rarely passed on to the next generation.
Output (English): B