Task: Question Generation
Input (English): Context: Albuminuria and a low estimated glomerular filtration rate (eGFR) are widely recognised indices of kidney dysfunction and have been linked to cardiovascular events, including stroke. We evaluated albuminuria, measured using the urinary albumin/creatinine ratio (UACR), and the eGFR in the acute phase of ischemic stroke, and investigated the clinical characteristics of ischemic stroke patients with and those without kidney dysfunction.', 'The study included 422 consecutive patients admitted between June 2010 and May 2012. General blood and urine examinations were performed at admission. Kidney dysfunction was defined as a low eGFR (<60\u2009mL/min/1.73\u2009m', 'Kidney dysfunction was diagnosed in 278 of the 422 patients (65.9%). The eGFR was significantly lower and UACR was significantly higher in patients with a poor outcome than in those with a good outcome. In multivariate analyses performed after adjusting for confounding factors, UACR >31.2\u2009mg/g creatinine (OR, 2.58; 95% CI, 1.52-4.43; P\u2009=\u20090.0005) was independently associated with a poor outcome, while a low eGFR was not associated.
Answer: A high UACR at admission may predict a poor outcome at discharge in patients with acute ischemic stroke.
Output (English): Does high urinary albumin/creatinine ratio at admission predict poor functional outcome in patients with acute ischemic stroke?