Task: Question Generation
Input (English): Context: Nitric oxide (NO) is an important vascular signalling molecule. NO is synthesised endogenously by endothelial nitric oxide synthase (eNOS). An alternate pathway is exogenous dietary nitrate, which can be converted to nitrite and then stored or further converted to NO and used immediately. Atherosclerosis is associated with endothelial dysfunction and subsequent lesion formation. This is thought to arise due to a reduction in the bioavailability and/or bioactivity of endogenous NO.', 'To determine if dietary nitrate can protect against endothelial dysfunction and lesion formation in the ApoE', 'ApoE
Answer: Low and moderate dose nitrate significantly improved endothelial function and atherosclerotic plaque composition in ApoE
Output (English): Does low dose dietary nitrate improve endothelial dysfunction and plaque stability in the?