Task: Question Answering
Input (English): Question: In choosing the type of cardiac valvular prosthesis (biological or mechanical) to be implanted in a patient, various aspects and characteristics of the patient and the prosthesis must be considered. In view of the aforementioned, point out the INCORRECT statement: 
 Options:  <1> Permanent anticoagulation is necessary in mechanical prostheses. <2> In general, biological prostheses are indicated in young patients, with long life expectancy. <3> Biological prostheses would be indicated in cases that present a formal contraindication for anticoagulation. <4> The rate of structural deterioration of a biological prosthesis is inversely proportional to the age of the subject. <5> Biological prostheses do not require permanent anticoagulation.
Output (English): 2