Task: Question Answering
Input (English): Question: The hormonal stimulation of the formation of the second messenger inositol 1,4,5-trisfosfato (IP3) quickly leads to the release of what other intracellular messenger: 
 Options:  <1> Cyclic AMP. <2> Prostaglandin <3> Calcium. <4> Leukotriene <5> Thromboxane
Output (English): 3