Task: Question Answering
Input (English): Question: Chronic interstitial nephropathies affect the tubular structures and the renal interstitium. If we analyze the functional defects that these pathologies can produce, we will NOT wait to find: 
 Options:  <1> Isostenuria. <2> Hypochloremic metabolic alkalosis. <3> Tubular atrophy and interstitial fibrosis in the renal histological study. <4> Normal or little expressive urinary sediment. <5> Proteinuria of less than 2 grams per day.
Output (English): 2