Task: Question Answering
Input (English): Question: Acetyl-CoA: 
 Options:  <1> It is synthesized from pyruvate in the eukaryotic cytoplasm. <2> It has a phosphate bond rich in energy. <3> Presents a guanine nucleotide in coenzyme A. <4> Activates pyruvate carboxylase and inhibits pyruvate dehydrogenase. <5> It easily crosses the mitochondrial inner membrane.
Output (English): 4