Task: Question Answering
Input (English): Question: In the synthesis of DNA, the quinolones act: 
 Options:  <1> Joining the double helix and thus blocking the progress of the replication fork. <2> Interlacing in the double helix and thus causing errors in the transcription. <3> On DNA gyrase. <4> As nucleotide analogs that are incorporated into DNA. <5> About DNA polymerases.
Output (English): 3