Task: Question Answering
Input (English): Question: The development of B cells in the bone marrow: 
 Options:  <1> It is dependent on the antigen. <2> It begins with gene rearrangements in the kappa light chain. <3> It is dependent on stromal cells. <4> It begins with gene rearrangements in the delta heavy chain. <5> It is dependent on T lymphocytes.
Output (English): 3