Task: Question Answering
Input (English): Question: In response to an increase in the concentration of adrenaline and circulating glucagon: 
 Options:  <1> It activates the phosphorylation of glycogen phosphorylase and the degradation of glycogen. <2> It increases the intracellular concentration of cAMP, and therefore, the synthesis of glycogen. <3> It decreases the intracellular concentration of cAMP and the degradation of glycogen. <4> The phosphorylation of glycogen synthase and glycogen synthesis is activated. <5> Increases the intracellular concentration of ATP and glycogenesis.
Output (English): 1