Task: Question Answering
Input (English): Question: The differential modification of RNA: 
 Options:  <1> It can result in multiple products from one gene. <2> It occurs thanks to the transcription bubble. <3> It is catalyzed by RNA polymerase I. <4> It is catalyzed by RNA polymerase II. <5> It is catalyzed by RNA polymerase III.
Output (English): 1