Task: Question Answering
Input (English): Question: What is the role of the helicase in replication ?: 
 Options:  <1> Join the single-stranded DNA to prevent the double helix from forming again. <2> Catalyze the union of nucleotides. <3> Correct the errors that occur in the replication. <4> Synthesize a primer to start replication. <5> Mechanically separate the strands of double-stranded DNA.
Output (English): 5