Task: Question Answering
Input (English): Question: Which of the following pharmacokinetic characteristics of rosiglitazone is NOT correct ?: 
 Options:  <1> It has a bioavailability of 99% <2> The inactive metabolites are eliminated by urine after conjugation or in the form of sulfates. <3> It should not be prescribed in patients with liver disease. <4> It is necessary to readjust your dosage in the presence of kidney disease. <5> It should not be prescribed to the nursing mother.
Output (English): 4