Task: Question Answering
Input (English): Question: When memory adapts to the presence of a drug (eg, subsensitizing receptors, synthesizing new membrane proteins) in such a way that the ability of the drug (eg, in alcohol to disrupt neuronal membranes) is increasingly minor, we are talking about: 
 Options:  <1> Psychological tolerance <2> Cross tolerance <3> Metabolic tolerance <4> Pharmacological tolerance. <5> Reduced tolerance
Output (English): 4