Task: Question Answering
Input (English): Question: In relation to intraductal papillary mucinous tumors of the pancreas, point out the WRONG statement: 
 Options:  <1> They are potentially malignant tumors. <2> Its frequency has increased notably in the last decade. <3> Three subtypes are distinguished: main conduit, secondary conduit and mixed conduit. <4> They should be excised as soon as they are diagnosed, except the main duct variety. <5> Its first clinical manifestation can be a picture of acute pancreatitis.
Output (English): 4