Task: Question Answering
Input (English): Question: Which of the following values ​​is closest to the estimated value for the standard free energy increase of ATP hydrolysis? 
 Options:  <1> - 1.4 Kcal / mol. <2> - 2.6 Kcal / mol. <3> + 3.5 Kcal / mol. <4> - 7.0 Kcal / mol. <5> + 7.0 Kcal / mol.
Output (English): 4