Task: Question Answering
Input (English): Question: Which of the following statements about the steady-state infusion of a drug is true? 
 Options:  <1> The concentration reached in steady state of equilibrium depends exclusively on the clearance. <2> The time necessary to reach the steady state of equilibrium depends on the volume of distribution. <3> The concentration reached in a steady state depends exclusively on the elimination half-life. <4> The concentration achieved in the steady state equilibrium depends on the clearance and the infusion rate. <5> The time required to reach the steady state of equilibrium depends on the clearance.
Output (English): 4