Task: Question Generation
Input (English): Context: I had a neurology appointment today . After the usual poking and prodding ( I have lost ten pounds because of the drugs ) I got to talk to my doctor and hear a phrase you never want to hear in medicine , " uh - oh . " We were talking about the fact I am having seizures daily still after trying 4 medicines . Several of these medicines have been at the safest highest dose .
Output (English): What might be the reason why the doctor said uh - oh ?