Task: Answer Verification
Input (English): Question: Are aBCB1 gene polymorphisms associated with treatment outcome in elderly acute myeloid leukemia patients?
Answer: In AML patients aged 60 years or older, allelic ABCB1 variations of C1236T, G2677T, or C3435T are not associated with altered P-gp function or with MDR1 expression at the transcriptional or translational level in leukemic blasts, and they do not significantly affect clinical prognosis.
Output (English): no