Task: Answer Verification
Input (English): Question: Are nonsense mutations in BAG3 associated with early-onset dilated cardiomyopathy in French Canadians?
Answer: Screening an extended panel of 41 candidate genes allowed us to identify probable pathogenic mutations in 69% of families with DCM in our cohort of mostly French-Canadian patients. We confirmed the prevalence of TTN nonsense mutations in DCM. Furthermore, to our knowledge, we are the first to present an association between nonsense mutations in BAG3 and early-onset DCM.
Output (English): yes