Task: Answer Verification
Input (English): Question: Is serum acid sphingomyelinase upregulated in chronic hepatitis C infection and non alcoholic fatty liver disease?
Answer: Chronic hepatitis C virus infection and non-alcoholic fatty liver disease induce a significant upregulation of serum acid sphingomyelinase which appears as a novel biomarker in chronic hepatopathies. Further studies are required to elucidate the potential of the sphingolipid signaling pathway as putative therapeutic target in chronic liver disease.
Output (English): yes