Task: Answer Verification
Input (English): Question: Does the presence of functionally relevant toll-like receptor polymorphisms significantly correlate with development or outcome of sepsis?
Answer: None of the investigated SNPs clearly predicted outcome of sepsis-related multiorgan failure. TLR2-R753Q SNP may be a useful marker to identify patients with high risk to develop infections at ICU admission but should be validated in larger studies. Future SNP-arrays investigating predisposition for infection should include this SNP alone or in combination with other functionally relevant SNPs.
Output (English): no