Task: Answer Verification
Input (English): Question: Does aggregated LDL in contact with macrophages induce local increases in free cholesterol levels that regulate local actin polymerization?
Answer: We describe a novel process that occurs during agLDL-macrophage interactions in which local release of free cholesterol causes local actin polymerization, promoting a pathological positive feedback loop for increased catabolism of agLDL and eventual foam cell formation.
Output (English): yes