Task: Answer Verification
Input (English): Question: Do igG antibodies to type II collagen reflect inflammatory activity in patients with rheumatoid arthritis?
Answer: Increased IgG anti-CII in sera and SF in RA correlated directly with acute phase reactants and the proinflammatory cytokines TNF-alpha and IL-6. Our data suggest that IgG anti-CII could reflect inflammatory activity with a potential to destroy cartilage in the early stages of RA.
Output (English): yes