Task: Answer Verification
Input (English): Question: Does pre-treatment with prednisolone improve the efficacy of subsequent alpha interferon therapy in chronic hepatitis C?
Answer: Prednisolone administration and withdrawal induced a rebound in ALT activity and a decrease in HCV-RNA serum concentration in about one third of the patients with chronic hepatitis C. However, these changes did not enhance the effectiveness of subsequent alpha interferon therapy.
Output (English): no