Task: Answer Verification
Input (English): Question: Does 4-Hydroxyisoleucine ameliorate an insulin resistant-like state in 3T3-L1 adipocytes by regulating TACE/TIMP3 expression?
Answer: 4-HIL improved an obesity-associated IR-like state in 3T3-L1 adipocytes by targeting TACE/TIMP3 and the insulin signaling pathway.
Output (English): yes