Task: Answer Verification
Input (English): Question: Is the G-308A variant of the Tumor Necrosis Factor-alpha ( TNF-alpha ) gene associated with obesity , insulin resistance and body fat distribution?
Answer: Our study did not detect any significant association of the G-308A TNFalpha polymorphism with obesity or with its clinical and metabolic abnormalities in this population. Our data suggests that, in our population, the G-308A TNFalpha polymorphism is unlikely to play a major role in the pathogenesis of these conditions.
Output (English): no