Task: Answer Verification
Input (English): Question: Is total Phenytoin concentration well correlated with active free drug in critically-ill head trauma patients?
Answer: Our results indicated that total phenytoin serum concentration is not a reliable therapeutic goal for drug monitoring in severely-ill head trauma patients even in the absence of hypoalbuminemia, renal and hepatic failure. It seems justifiable to measure free phenytoin concentration in all severely ill neurotrauma patients.
Output (English): no