Task: Answer Verification
Input (English): Question: Do rheumatoid factor and anti-CCP predict progressive joint damage in patients with early rheumatoid arthritis treated with prednisolone : a randomised study?
Answer: The presence of RF and anti-CCP predicted radiographic progression in patients not treated with prednisolone but failed to predict progression in patients treated with this drug. The data suggest that early treatment with prednisolone may modulate not only inflammation but also autoimmunity-associated pathogenetic mechanisms.
Output (English): no