Task: Answer Verification
Input (English): Question: Does in vitro exposure of bacteria to antimicrobial impregnated-central venous catheters directly lead to the emergence of antimicrobial resistance?
Answer: Our in vitro data suggest that the exposure of Gram-positive cocci to either rifampin or minocycline can lead to the development of resistance. However, exposure of bacteria to these antibiotics in combination does not directly lead to resistance. Clinical investigations will be required to determine the true risk and implications of the development of resistance.
Output (English): no