Task: Answer Verification
Input (English): Question: Does treatment with anti-HMGB1 monoclonal antibody affect lupus nephritis in MRL/lpr mice?
Answer: Treatment with monoclonal anti-HMGB-1 antibody 2G7 does not affect development of lupus nephritis, disease progression or pro-inflammatory cytokines levels in MRL/lpr mice. This indicates that blocking of HMGB1 by this neutralizing antibody does not affect lupus nephritis in MRL/lpr mice.
Output (English): no