Task: Answer Verification
Input (English): Question: Does type-1 Collagen differentially alter beta-catenin accumulation in primary Dupuytren 's Disease cord and adjacent palmar fascia cells?
Answer: Our findings implicate type-1 collagen as a previously unrecognized regulator of beta-catenin accumulation and a modifier of TGF-beta1 signaling specifically in primary DD cells. These data have implications for current treatment modalities as well as the design of in vitro models for research into the molecular mechanisms of DD.
Output (English): yes