Task: Paraphrasing
Input (English): Question: A sealed, vacuum-insulated reaction flask approximates what condition, in which neither matter nor heat can be exchanged between system and surroundings? 
Answer: isolated system. 
Sentence: A sealed, vacuum-insulated reaction flask approximates the condition of a isolated system, in which neither matter nor heat can be exchanged between system and surroundings.
Output (English): By using a sealed, vacuum-insulated reaction flask, scientists can approximate an isolated system, which is a system in which neither matter, nor energy, can be exchanged between the system and the surroundings.