Task: Answer Verification
Input (English): Question: Does herpes simplex virus type 2 coinfection accelerate CD4 count decline in untreated HIV infection?
Answer: HSV-2 coinfection was not associated with the rate of CD4 count decline during ART-untreated HIV infection, but was associated with an earlier combined endpoint of ART initiation or CD4 <350 cells/mm(3). Attenuating effects of acyclovir on HIV disease progression observed in recent clinical trials may result from direct anti-HIV activity rather than indirect benefits from HSV-2 suppression.
Output (English): no