Task: Answer Verification
Input (English): Question: Is microsatellite instability in human colonic cancer a useful clinical indicator of familial colorectal cancer?
Answer: Although some very small, and as yet undefined, proportion of colon cancer may be caused by inherited mutations leading to microsatellite instability, tumoral instability by itself is not a marker for familiality and should not be considered as evidence for an inherited syndrome.
Output (English): no