Task: Answer Verification
Input (English): Question: Does lung-targeted RNA interference against angiopoietin-2 ameliorate multiple organ dysfunction and death in sepsis?
Answer: The Tie2 antagonist angiopoietin-2 represents a promising target against sepsis-associated multiple organ dysfunction. A novel RNA interference therapeutic approach targeting gene expression in the pulmonary endothelium could be a clinically relevant pharmacological strategy to reduce injurious angiopoietin-2 synthesis.
Output (English): yes