Task: Answer Verification
Input (English): Question: Do aCTN3 R577X genotypes associate with Class II and deepbite malocclusions?
Answer: ACTN3 577XX is overrepresented in subjects with skeletal Class II malocclusion, suggesting a biologic influence during bone growth. ACTN3 577XX is underrepresented in subjects with deepbite malocclusion, suggesting that muscle differences contribute to variations in vertical facial dimensions.
Output (English): yes