Task: Answer Verification
Input (English): Question: Does celastrol potentiate radiotherapy by impairment of DNA damage processing in human prostate cancer?
Answer: Celastrol sensitized PC-3 cells to radiation both in vitro and in vivo by impairing DNA damage processing and augmenting apoptosis. Celastrol might represent a promising new adjuvant regimen for the treatment of hormone-refractory prostate cancer.
Output (English): yes