Task: Answer Verification
Input (English): Question: Is increased insulin-like growth factor 1 production by human osteoarthritic chondrocytes dependent on growth hormone action?
Answer: This study indicates that the elevated synthesis of IGF-1 by adult human OA chondrocytes occurs through a GH/GHR-independent mechanism, suggesting that other factors are capable of controlling local IGF-1 production in these cells.
Output (English): no