Task: Answer Verification
Input (English): Question: Does methotrexate inhibit NF-κB activity via long intergenic ( noncoding ) RNA-p21 induction?
Answer: Our findings support a model whereby depressed levels of lincRNA-p21 in RA contribute to increased NF-κB activity. MTX decreases basal levels of NF-κB activity by increasing lincRNA-p21 levels through a DNA PKcs-dependent mechanism.
Output (English): yes