Task: Answer Verification
Input (English): Question: Does manual blood exchange transfusion significantly contribute to parasite clearance in artesunate-treated individuals with imported severe Plasmodium falciparum malaria?
Answer: Manual exchange transfusion does not significantly contribute to parasite clearance in artesunate-treated individuals. There may be a small effect of ET on parasite clearance under quinine treatment. Institution of ET to promote parasite clearance in settings where artesunate is available is not recommended, at least not with manually executed exchange procedures.
Output (English): no