Task: Answer Verification
Input (English): Question: Does ghrelin hyporesponsiveness contribute to age-related hyperinflammation in septic shock?
Answer: These findings suggest that the reduced central (brain) responsiveness to ghrelin due to the decreased GH, plays a major role in producing the hyperinflammatory state, resulting in severe organ injuries and high mortality after endotoxemia in aged animals. Ghrelin and GH can be developed as a novel therapy for sepsis in the geriatric population.
Output (English): yes