Task: Answer Verification
Input (English): Question: Does cT60 genotype affect CTLA-4 isoform expression despite association to T1D and AITD in northern Sweden?
Answer: Association was found between T1D/AITD and all three polymorphisms investigated. However, in contrast to previous investigations, sCTLA-4 RNA and protein expression levels did not differ based on CT60 genotype. Our results do not rule out the CT60 SNP as an important polymorphism in the development of T1D or AITD, but suggest that further investigations are necessary to elucidate the effect of the CTLA-4 region on the development of T1D and AITD.
Output (English): no