Task: Answer Verification
Input (English): Question: Does bone morphogenetic protein 7 sensitize O6-methylguanine methyltransferase expressing-glioblastoma stem cells to clinically relevant dose of temozolomide?
Answer: These data support the view that reduced endogenous BMP7 expression/signaling in GSC may contribute to maintained stemness, EMT, and chemoresistant phenotype, suggesting that BMP7 treatment may provide a novel strategy in combination with TMZ for an effective treatment of glioblastoma exhibiting unmethylated MGMT.
Output (English): yes