Task: Answer Verification
Input (English): Question: Does 5 ' flanking region polymorphism of the gene encoding leukotriene C4 synthase correlate with the aspirin-intolerant asthma phenotype in the United States?
Answer: Our data demonstrate that the C-444 allele in the LTC4S gene is not statistically different among patients with the aspirin-intolerant asthmatic phenotype, patients with the aspirin-tolerant asthmatic phenotype, and unaffected control subjects in the United States. This finding, along with the lack of functionality of this polymorphism, suggest that it is not related to a specific asthma phenotype and may represent a population-stratified polymorphism within patients of eastern European descent.
Output (English): no