Task: Answer Verification
Input (English): Question: Does substance P mediate pro-inflammatory cytokine release form mesenteric adipocytes in Inflammatory Bowel Disease patients?
Answer: Preadipocyte SP-NK-1R interactions during IBD may participate in IBD pathophysiology. The ability of human preadipocytes to release IL-17A in response to SP together with increased IL-17A receptor in IBD colon opens the possibility of a fat-colonic mucosa inflammatory loop that may be active during IBD.
Output (English): yes