Task: Answer Verification
Input (English): Question: Does pCSK9-deficiency alter blood pressure and sodium balance in mouse models of hypertension?
Answer: Despite an increase of cleaved αENaC under basal condition, PCSK9(-/-) mice display normal sodium balance and blood pressure regulation. Altogether, these data are reassuring regarding the development of PCSK9 inhibitors in hypercholesterolemia.
Output (English): no