Task: Answer Verification
Input (English): Question: Does mesenteric lymph diversion abrogate 5-lipoxygenase activation in the kidney following trauma and hemorrhagic shock?
Answer: 5-LO and FLAP colocalize in the interstitium of the renal medulla following T/HS. MLD attenuates this phenomenon, which coincides with pathologic changes seen in tubules during kidney injury and biochemical evidence of AKI. These data suggest that gut-derived leukotriene substrate predisposes the kidney and the lung to subsequent injury.
Output (English): yes