Task: Answer Verification
Input (English): Question: Is the CGGGG insertion/deletion polymorphism of the IRF5 promoter a strong risk factor for primary Sjögren 's syndrome?
Answer: Our findings indicate an association of the CGGGG insertion/deletion polymorphism of the IRF5 promoter with primary SS. Patients carrying the 4R CGGGG IRF5 allele had a high level of mRNA for IRF5 in PBMCs and salivary gland epithelial cells, mainly after in vitro viral infection. Patients with high levels of mRNA for IRF5 also had high levels of mRNA for type I IFN-induced genes in PBMCs.
Output (English): yes