Task: Answer Verification
Input (English): Question: Does blocking of platelets or intrinsic coagulation pathway-driven thrombosis prevent cerebral infarctions induced by photothrombosis?
Answer: Our data demonstrate that platelet activation, factor XII-driven thrombus formation, and plasmatic coagulation pathways downstream of FX are not a prerequisite for ensuing tissue damage in models of photothrombotic vessel injury indicating that other pathomechanisms are involved. We suggest that this widely used model does not depend on platelet- or plasmatic coagulation-derived thrombosis.
Output (English): no