Task: Answer Verification
Input (English): Question: Do pre-treatment serum total bilirubin level as an indicator of optimal CPT-11 dosage?
Answer: PTB can be used as a predictive marker of CPT-11-induced severe neutropenia and FN. In patients with PTB ≥0.8 mg/dL, the CPT-11 dose should be reduced to less than 80 mg/m(2) with weekly dosing.
Output (English): yes