Task: Answer Verification
Input (English): Question: Does lidocaine inhibit epithelial chemokine secretion via inhibition of nuclear factor kappa B activation?
Answer: Lidocaine inhibits IL-8 and IP-10 secretion from intestinal cells. This effect is mediated by inhibition of NFkappaB activation via decreased IkappaB phosphorylation and is not mediated by lidocaine's effect on VGSC.
Output (English): yes