Task: Answer Verification
Input (English): Question: Does sclerostin play a major role in the pathogenesis of skeletal complications in type 2 diabetes mellitus?
Answer: T2DM results in impaired skeletal architecture through altered remodelling pathways, but despite altered serum levels, it does not appear that sclerostin contributes to the deleterious effect of T2DM in rat bone.
Output (English): no