Task: Answer Verification
Input (English): Question: Does sUMOylation of Grb2 enhance the ERK activity by increasing its binding with Sos1?
Answer: Our results provide evidences that Grb2 is SUMOylated in vivo and this modification enhances ERK activities via increasing the formation of Grb2-Sos1 complex, and may consequently promote cell motility, transformation and tumorigenesis.
Output (English): yes