Task: Answer Verification
Input (English): Question: Is a globally occurring indel polymorphism in the promoter of the IFNA2 gene associated with severity of malaria but with the positivity rate of HCV?
Answer: Polymorphisms in genes involved in the interferon pathway have been implicated in the resistance or susceptibility against cerebral malaria and HBV. Here we show that an indel polymorphism, which mediates a disadvantageous effect in HBV patients, may also play a disadvantageous role in HCV infections stressing the importance of a fully functional interferon pathway.
Output (English): no