Task: Answer Verification
Input (English): Question: Does oritavancin induce Clostridium difficile germination and toxin production in hamsters or a human gut model?
Answer: Oritavancin exposure, unlike exposure to vancomycin or clindamycin, did not lead to CDI in hamsters. In both models, oritavancin reduced C. difficile total counts and spores to below detectable limits. The data indicate the potential of oritavancin for CDI treatment, since exposure did not induce C. difficile germination and toxin production, which are known to exacerbate the disease state.
Output (English): no