Task: Answer Verification
Input (English): Question: Does overexpression of complement component C5a accelerate the development of atherosclerosis in ApoE-knockout mice?
Answer: C5a overexpression could accelerate the development of atherosclerosis in ApoE-/- mice by promoting macrophage recruitment, foam cell formation and inflammatory activation. Furthermore, its proatherogetic role is mediated by the C5a receptor.
Output (English): yes