Task: Answer Verification
Input (English): Question: Does macrophage-activating lipopeptide-2 require Mal and PI3K for efficient induction of heme oxygenase-1?
Answer: These results indicated that MALP-2 required TLR2/6, Btk, Mal and c-Src to activate PI3K, which in turn initiated the activation of Nrf2 for efficient HO-1 induction.
Output (English): yes