Task: Answer Verification
Input (English): Question: Does aberrant interleukin-1 signalling increase susceptibility of mice to NOD2-dependent uveitis?
Answer: Our findings highlight the complexity of NOD2 activation and IL-1 signalling effects that can be compounded by local environmental factors of the target organ. These observations may impact how we understand the molecular mechanisms by which NOD2 influences inflammation of the eye versus joint, and consequently, treatment options for uveitis versus arthritis.
Output (English): no