Task: Answer Verification
Input (English): Question: Does combined elevation of microRNA-196a and microRNA-196b in sera predict unfavorable prognosis in patients with osteosarcomas?
Answer: Our present data indicate the involvement of miR-196a and miR-196b upregulation in the pathogenesis of osteosarcoma. More importantly, the altered levels of circulating miR-196a and miR-196b might have great potential to serve as novel and non-invasive prognostic factors for this malignancy.
Output (English): yes