Task: Answer Verification
Input (English): Question: Do maternal Nrf2 and gluthathione-S-transferase polymorphisms modify associations of prenatal tobacco smoke exposure with asthma and lung function in school-aged children?
Answer: This study confirms a detrimental effect of intrauterine tobacco smoke exposure on childhood lung function but no strong evidence of modification by maternal genotype for important antioxidant genes. Adverse effects of fetal exposure to tobacco smoke on the respiratory health of children may be mediated by pathways other than oxidative stress.
Output (English): no