Task: Answer Verification
Input (English): Question: Does acute or subchronic clozapine treatment ameliorate prepulse inhibition ( PPI ) deficits in CPB-K mice with low levels of hippocampal NMDA receptor density?
Answer: In summary, (1) this study confirmed our working hypothesis: Lower levels of hippocampal glutamatergic receptor densities correspond to lower sensorimotor gating in CPB-K mice, and (2) acute or subchronic treatment with CLZ did not elevate low PPI levels in CPB-K mice. Thus, further experiments will concentrate on other antipsychotic drugs to prove the predictive validity of this animal model.
Output (English): no