Task: Answer Verification
Input (English): Question: Is pyrazinamide active against Mycobacterium tuberculosis residing in cultured human monocyte-derived macrophages?
Answer: PZA has neither bacteriostatic nor bactericidal activity against M. tuberculosis persisting or multiplying in cultured monocyte-derived human macrophages, and it might be that the well-known effectiveness of this drug in tuberculosis patients is not related to its supposed activity against intracellular bacterial subpopulations.
Output (English): no