Task: Answer Verification
Input (English): Question: Does super-high-dose methylprednisolone improve efficacy or induce glucocorticoid resistance in experimental allergic encephalomyelitis?
Answer: This study indicates that the GRα/GRβ ratio is associated with GC sensitivity, and SRp30c may play an important role in promoting alternative splicing of GR pre-mRNA to generate GRβ in EAE rats. Compared with low-dose MP, SHD MP does not improve efficacy or induce GC resistance.
Output (English): no