Task: Answer Verification
Input (English): Question: Are beta defensin-1 gene ( DEFB1 ) polymorphisms associated with atopic dermatitis in children and adolescents from northeast Brazil ( Recife , Pernambuco )?
Answer: Our results seem to exclude a role for the -44 C/G DEFB1 SNPs on the pathogenesis and severity of AD, while for the -20 C/G and -52 G/A, even if not statistically significant, we evidenced a slight trend for susceptibility (-20 GG) and protection (-52 GG) for the development of AD. However, as controversial findings have been reported in the literature, the role of DEFB1 in the development of AD and in the severity of the phenotype deserves further investigation.
Output (English): no