Task: Answer Verification
Input (English): Question: Do induction pegylated interferon alfa-2a and high dose ribavirin increase SVR in heavy patients with HCV genotype 1 and high viral loads?
Answer: In patients infected with HCV genotype 1 who are difficult to treat (high viral load, body weight ≥85 kg), a 12-week induction regimen of peginterferon alfa-2a and/or higher-dose ribavirin is not more effective than the standard regimen.
Output (English): no