Task: Answer Verification
Input (English): Question: Does herpes simplex virus type I require productive infection to induce tissue factor in human umbilical vein endothelial cells?
Answer: HSV-1 induces PCA in HUVEC which is clearly TF-dependent; this response does not require viral replication. These data indicate increased complexity in HSV interactions with vascular endothelium and imply induction of some procoagulant functions by nonproductive infection.
Output (English): no