Task: Answer Verification
Input (English): Question: Do triangle network motifs predict complexes by complementing high-error interactomes with structural information?
Answer: Given high-error PPINs with missing information, triangles of mixed datatypes are a promising direction for finding protein complexes. Integrating PPINs with SDDIs improves finding complexes. Structural SDDIs partially explain the high functional similarity of second-level neighbors in PPINs. We estimate that relatively little structural information would be sufficient for finding complexes involving most of the proteins and interactions in a typical PPIN.
Output (English): yes