Task: Answer Verification
Input (English): Question: Does common large partial VWF gene deletion cause alloantibody formation in the Hungarian type 3 von Willebrand disease population?
Answer: We report the genetic background of the entire Hungarian type 3 VWD population. A large novel deletion, most probably due to a founder effect, seems to be unique to Hungarian type 3 VWD patients with high allele frequency. In contrast to previous reports, none of the five patients homozygous for the large partial deletion developed inhibitors to VWF. This discrepancy raises the possibility of selection bias in some of the reports.
Output (English): no