Task: Answer Verification
Input (English): Question: Does the apolipoprotein-AI mimetic peptide L4F at a modest dose attenuate weight gain , inflammation , or atherosclerosis in LDLR-null mice?
Answer: Our results suggest that neither L4F (100 µg/day/mouse) nor apoA-I overexpression affects adiposity or insulin resistance in this model. We also were unable to confirm a reduction in atherosclerosis with L4F in our particular model. Further studies on the effect of apoA-I mimetics on atherosclerosis and insulin resistance in a variety of dietary contexts are warranted.
Output (English): no