Task: Answer Verification
Input (English): Question: Does human cytomegalovirus infection induce leukotriene B4 and 5-lipoxygenase expression in human placentae and umbilical vein endothelial cells?
Answer: The presence of HCMV coincided with high 5-LO expression in cells of in vivo HCMV infected placentae. HCMV induced up-regulation of 5-LO in both ex vivo HCMV-infected placental explants and HUVEC. HCMV induced LT-biosynthesis in congenitally infected placentae may have a role in pathogenesis of congenital HCMV disease.
Output (English): yes