Task: Answer Verification
Input (English): Question: Is the Alpha-defensin Test for Periprosthetic Joint Infections Affected by Prior Antibiotic Administration?
Answer: The alpha-defensin test maintains its concentration and sensitivity for PJI even in the setting of antibiotic administration. Furthermore, among patients with PJI on antibiotics, the alpha-defensin tests demonstrated a higher sensitivity in detecting PJI when compared with the ESR, CRP, fluid PMN%, and fluid culture. The high sensitivity of the alpha-defensin test, even in the setting of prior antibiotic treatment, provides excellent utility as a screening test for PJI.
Output (English): no