Task: Answer Verification
Input (English): Question: Does tolerance to the therapeutic effect of tadalafil occur during 6 months of treatment : A randomized , double-blind , placebo-controlled study in men with erectile dysfunction?
Answer: Tadalafil treatment significantly improved SEP3 and IIEF EF domain scores. The efficacy of tadalafil, taken as needed, was maintained over a 6-month treatment period in men with ED.
Output (English): no