Task: Answer Verification
Input (English): Question: Does deregulated expression of promyelocytic leukemia zinc finger protein in B-cell chronic lymphocytic leukemias affect cyclin A expression?
Answer: The lower survival of patients with the highest levels of PLZF suggests that this protein may be a marker of progression in B-CLL. The absence of co-ordinated regulation of PLZF and cyclin A genes in B-CLL and in a malignant B-cell line may indicate a loss of cyclin A control by PLZF in B-CLL and other B-cell disorders. Deregulation of PLZF could thus play a role in B-cell malignancy.
Output (English): no