Task: Answer Verification
Input (English): Question: Does pINK1 trigger autocatalytic activation of Parkin to specify cell fate decisions?
Answer: Autocatalytic activation of Parkin bolsters its accumulation on mitochondria and apoptotic response to valinomycin. Our results suggest that PINK1-Parkin constitutes a damage-gated molecular switch that governs cellular-context-specific cell fate decisions in response to variable stress stimuli.
Output (English): yes