Task: Answer Verification
Input (English): Question: Does ventilation with `` clinically relevant '' high tidal volumes promote stretch-induced injury in the lungs of healthy mice?
Answer: Tidal volumes up to 20 mL/kg are unlikely to induce substantial lung overstretch in models using healthy, young mice. Signs of injury/inflammation using such models are likely to result from other factors, particularly alveolar derecruitment and atelectasis. The results of such studies may need to be reevaluated before clinical relevance can be accurately determined.
Output (English): no