Task: Answer Verification
Input (English): Question: Is palmitate-Induced MMP-9 Expression in the Human Monocytic Cells Mediated through the TLR4-MyD88 Dependent Mechanism?
Answer: Altogether, these results show that palmitate induces TLR4-dependent activation of MMP-9 gene expression, which requires the recruitment of MyD88 leading to activation of NF-kB/AP-1 transcription factors. Thus, our findings suggest that the palmitate-induced MMP-9 secretion might be an underlying mechanism of its increased levels in obesity and related metabolic inflammation.
Output (English): yes