Task: Answer Verification
Input (English): Question: Is a functional synonymous coding variant in the IL1RN gene associated with survival in septic shock?
Answer: In European ancestry subjects, the IL1RN variant rs315952C is preferentially transcribed and associated with increased evoked plasma IL1RA and with improved survival from septic shock. It may be that genetically determined IL1RA levels influence survival from septic shock.
Output (English): yes