Task: Answer Verification
Input (English): Question: Do splenic stromal niches support hematopoiesis of dendritic-like cells from precursors in bone marrow and spleen?
Answer: The outcome has been development of a coculture system that supports hematopoiesis of immature myeloid dendritic-like cells in vitro. Although production of monocytes can occur in the presence of stroma-conditioned medium alone, production of DC is dependent on stromal cell interaction. Results presented here raise questions about the role of spleen as a site for DC hematopoiesis from endogenous precursors.
Output (English): yes