Task: Answer Verification
Input (English): Question: Does pentobarbital have curare-like effects on adult-type nicotinic acetylcholine receptor channel currents?
Answer: The interaction between adult-type nicotinic acetylcholine receptors, acetylcholine, and pentobarbital was biophysically investigated by using the patch-clamp technique in combination with tools for ultrafast solution exchange. PB elicited open-channel block and competitive block of nicotinic acetylcholine receptor channel currents, whereas the latter seems to be effective in clinically relevant concentrations.
Output (English): yes