Task: Answer Verification
Input (English): Question: Is methylglyoxal associated with changes in kidney function among individuals with screen-detected Type 2 diabetes mellitus?
Answer: In a population of people with screen-detected Type 2 diabetes, we observed associations between methylglyoxal and markers of renal function: 6-year change in methylglyoxal was inversely associated with 6-year change in eGFR. Also, methylglyoxal at baseline was positively associated with ACR at baseline. Our study lends further support to a role for methylglyoxal in the pathogenesis of diabetic nephropathy.
Output (English): yes