Task: Answer Verification
Input (English): Question: Does zuo Jin Wan reverse P-gp-mediated drug-resistance by inhibiting activation of the PI3K/Akt/NF-κB pathway?
Answer: Our study has provided the first direct evidence that ZJW reverses drug-resistance in human colorectal cancer by blocking the PI3K/Akt/NF-κB signaling pathway, and could be considered as a useful drug for cancer therapy.
Output (English): yes