Task: Answer Verification
Input (English): Question: Does genetic background of nonmutant Piebald-Virol-Glaxo rats influence nephronophthisis phenotypes?
Answer: The genetic background of the nonmutant PVG rats does not influence the genetic and phenotypic inheritance of CKD from mutant Lewis polycystic kidney rats. A single recessive mutation incapacitated the gene, which relaxed its functional constraints, and led to formation of multiple cysts in the kidneys of the homozygous mutant rats.
Output (English): no