Task: Answer Verification
Input (English): Question: Are cholangiocarcinoma in primary sclerosing cholangitis : K-ras mutations and Tp53 dysfunction implicated in the neoplastic development?
Answer: We conclude that K-ras mutations and p53 dysfunction are implicated in tumorigenesis of cholangiocarcinomas arising in PSC patients and that these abnormalities together with increased Ki-67 index may indicate neoplastic progression of bile ducts in these patients.
Output (English): yes