Task: Answer Verification
Input (English): Question: Does notochord manipulation impact oesophageal and tracheal formation from isolated foregut in 3D explant culture?
Answer: The relationship between the embryonic foregut and notochord is complex and ill-defined; however, the notochord does not contribute essentially to oesophagus and trachea formation beyond E9 in the mouse, and the transplantation of additional notochord does not disrupt foregut separation in 3D explant culture.
Output (English): no