Task: Answer Verification
Input (English): Question: Does gastric cancer growth control by BEZ235 in vivo correlate with PI3K/mTOR target inhibition but with [ 18F ] FLT uptake?
Answer: In conclusion, in vivo sensitivity of gastric cancer xenografts to BEZ235 did not correlate with in vitro antiproliferative activity or in vivo PI3K/mTOR target inhibition by BEZ235. In contrast, [(18)F]FLT uptake was linked to BEZ235 in vivo sensitivity. Noninvasive [(18)F]FLT PET imaging might qualify as a novel marker for optimizing future clinical testing of dual PI3K/mTOR inhibitors.
Output (English): no