Task: Answer Verification
Input (English): Question: Is aortic valve calcification mediated by a differential response of aortic valve interstitial cells to inflammation?
Answer: Proinflammatory stimulation induces an osteogenic phenotype in aortic VICs but not mitral, pulmonic, or tricuspid VICs. We conclude that this differential osteogenic response of aortic VICs contributes to the pathogenesis of calcific aortic stenosis.
Output (English): yes