Task: Answer Verification
Input (English): Question: Does recipient T cell TIM-3 and hepatocyte galectin-9 signalling protect mouse liver transplants against ischemia-reperfusion injury?
Answer: Harnessing TIM-3/Gal-9 signalling at the T cell-hepatocyte interface facilitates homeostasis in IR-stressed orthotopic liver transplants. Enhancing anti-oxidant hepatocyte Gal-9 potentiates liver IR-resistance. Negative regulation by recipient TIM-3+CD4+ cells provides evidence for cytoprotective functions of a discrete T cell subset, which should be spared when applying T cell-targeted immunosuppression in transplant recipients.
Output (English): yes