Task: Answer Verification
Input (English): Question: Are the pharmacokinetics of darexaban affected to a clinically relevant degree by rifampicin , a strong inducer of P-glycoprotein and CYP3A4?
Answer: Overall, rifampicin did not affect the PK profiles of darexaban glucuronide and darexaban to a clinically relevant degree, suggesting that the potential for drug-drug interactions between darexaban and CYP3A4 or P-glycoprotein-inducing agents is low.
Output (English): no