Task: Answer Verification
Input (English): Question: Do hFE mutations modulate the effect of iron on serum hepcidin-25 in chronic hemodialysis patients?
Answer: Serum hepcidin-25 is increased in hemodialysis patients, regulated by iron stores and inflammation, and relatively reduced in subjects carrying frequent HFE mutations. Hepcidin-25 may contribute to the pathogenesis of anemia by decreasing iron availability.
Output (English): yes