Task: Answer Verification
Input (English): Question: Does the R271W mutant form of Pit-1 act as a dominant inhibitor of Pit-1 action to activate the promoters of GH and prolactin genes?
Answer: Taken together with the evidence that phenotypically normal cases have been reported with this mutation, our results deny the relationship between R271W and combined pituitary hormone deficiency.
Output (English): no