Task: Answer Verification
Input (English): Question: Does the RNA editing enzyme APOBEC1 induce somatic mutations and a compatible mutational signature is present in esophageal adenocarcinomas?
Answer: Our findings suggest that the ability of APOBEC1 to trigger genetic alterations represents a major layer in its oncogenic potential. Such APOBEC1-induced mutator phenotypes could play a role in the onset of esophageal adenocarcinomas. APOBEC1 could be involved in cancer promotion at the very early stages of carcinogenesis, as it is highly expressed in Barrett's esophagus, a condition often associated with esophageal adenocarcinoma.
Output (English): yes