Task: Answer Verification
Input (English): Question: Is n-methyl-D-aspartate receptor channel block by meperidine dependent on extracellular pH?
Answer: At acidic pH the potency of meperidine for N-methyl-D-aspartate-receptor channels was increased. Any antinociceptive and neuroprotective benefit from the N-methyl-D-aspartate-receptor antagonist property of meperidine may be pH dependent.
Output (English): yes