Task: Answer Verification
Input (English): Question: Does iGF-1 moderate the time-dependent transcriptional patterns of key homeostatic genes induced by sustained compression of bovine cartilage?
Answer: Sustained compression markedly altered the effects of IGF-1 on expression of genes involved in cartilage homeostasis, while IGF-1 was largely unable to moderate the transcriptional effects of compression alone. The demonstrated co-expressed gene pairings suggest a balance of anabolic and catabolic activity following simultaneous mechanical and growth factor stimuli.
Output (English): no