Task: Answer Verification
Input (English): Question: Does germinal center B cell depletion diminish CD4+ follicular T helper cells in autoimmune mice?
Answer: These data suggest that mature Tfh cells require signals from GC B cells to sustain their optimal numbers and function in both autoimmune and immunization models. Thus, immunotherapies targeting B cells in autoimmune disease may affect pathogenic Tfh cells.
Output (English): yes