Task: Answer Verification
Input (English): Question: Does preconditioning with the traditional Chinese medicine Huang-Lian-Jie-Du-Tang initiate HIF-1α-dependent neuroprotection against cerebral ischemia in rats?
Answer: Both rats and neurons subjected to HLJDT preconditioning were able to resist ischemia/reperfusion or hypoxia injury through the inhibition of apoptosis and the enhancement of proliferation, and these effects were primarily dependent on the activation of the PI3K/Akt signaling pathway and HIF-1α.
Output (English): yes