Task: Answer Verification
Input (English): Question: Does periodontitis promote the diabetic development of obese rat via miR-147 induced classical macrophage activation?
Answer: This study provided new evidence for the positive effect of periodontal inflammation on diabetic development, while the regulatory mechanism of miR-147 on classical macrophage activation, was verified, and presumed to contribute to the impaired glucose tolerance aggravated by periodontitis in obese rats. Besides, this study indicated the application of miR-147 for therapeutic approach in the treatment of diabetes with periodontitis.
Output (English): yes