Task: Answer Verification
Input (English): Question: Does tumor-α9β1 integrin-mediated signaling induce breast cancer growth and lymphatic metastasis via the recruitment of cancer-associated fibroblasts?
Answer: Tumor α9β1 integrin promotes lymphatic metastasis through enhancing invasion. Tumor α9β1 integrin promotes tumor growth through CAFs. Tumor α9β1 integrin enhances the recruitment of CAFs into the primary tumor. Tumor cells induce the production of OPN by CAFs in the primary tumor. CAF-derived OPN promotes tumor growth.
Output (English): yes