Task: Answer Verification
Input (English): Question: Is lactogenic differentiation of HC11 cells accompanied by downregulation of AP-2 transcription factor genes?
Answer: The extent of lactogenic differentiation of HC11 cells in vitro is limited compared to mammary epithelium undergoing secretory differentiation in vivo. Downregulation of AP-2 transcription factor genes is not required for lactogenic differentiation of HC11 cells but may functionally be involved in aspects of lactogenic differentiation in vivo that are not reflected by the HC11 system.
Output (English): no