Task: Answer Verification
Input (English): Question: Does transfusion of recently donated ( fresh ) red blood cells ( RBCs ) improve survival in comparison with current practice , while safety of the oldest stored units is yet to be established : a meta-analysis?
Answer: RCTs established that transfusion of 1- to 10-day-old stored RBCs is not superior to current practice. The apparent discrepancy in mortality between analyses of RCTs and observational studies may in part relate to differences in hypotheses tested and ages of stored RBCs studied. Further trials investigating 1- to 10-day-old stored RBC benefits would seem of lower priority than studies to determine whether 4- to 6-week stored units have safety and efficacy equivalent to the 2- to 3-week-old stored RBCs commonly transfused today.
Output (English): no