Task: Answer Verification
Input (English): Question: Does delta opioid activation of the mitogen-activated protein kinase cascade require transphosphorylation of receptor tyrosine kinases?
Answer: Taken together, these data suggest that the transactivation of resident RTKs does not appear to be required for OR-mediated ERK phosphorylation and that the tyrosine-phosphorylated delta-OR, itself, is likely to act as its own signalling scaffold.
Output (English): no