Task: Answer Verification
Input (English): Question: Does prediction of Thorough QT study result using action potential simulations based on ion channel screens?
Answer: This study provides a proof-of-principle for the prediction of human TQT study results using data available early in drug development. We highlight a number of areas that need refinement to improve the method's predictive power, but the results suggest that such approaches will provide a useful tool in cardiac safety assessment.
Output (English): yes