Task: Answer Verification
Input (English): Question: Does δNp63α enhance the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2?
Answer: Here, we report that GLI2 is the novel target gene of ΔNp63α and that ΔNp63α-GLI2 crosstalk in osteosarcoma cells is a necessary event in osteosarcoma progression. Defining the exact mechanisms involved in this interaction that mediate the pathogenesis of osteosarcoma promises to identify targets for drug therapy.
Output (English): yes