Task: Answer Verification
Input (English): Question: Does targeting of mitochondrial reactive oxygen species production avert lipid-induced insulin resistance in muscle tissue from mice?
Answer: SkQ treatment reduced muscle mitochondrial ROS production and prevented HF-induced oxidative stress. Nonetheless, whole-body glucose tolerance, insulin-stimulated glucose uptake, muscle insulin signalling and mitochondrial function were not improved. These results suggest that HF-induced oxidative stress is not a prerequisite for the development of muscle insulin resistance.
Output (English): no