Task: Answer Verification
Input (English): Question: Does leptin-mediated reactive oxygen species production significantly affect primary mouse hepatocyte functions in vitro?
Answer: Leptin induced higher ROS levels in primary hepatocytes than in LSECs and HSCs, depending on NADPH oxidase, MEK1 and JAK2 signalling but not on the long leptin receptor isoform. Furthermore, leptin exposure did not influence primary hepatocyte functionality negatively.
Output (English): no