Task: Answer Verification
Input (English): Question: Does hyperoxia inhibit nitric oxide treatment effects in alveolar epithelial cells via effects on L-type amino acid transporter-1?
Answer: SNO uptake after NO treatment is dependent on LAT1. Hyperoxia impairs SNO uptake and NO effects during NO exposure and impairs LAT system function and LAT1 expression. Effects on SNO formation and transport must be considered for rational optimization of NO-based therapeutics.
Output (English): yes