Task: Answer Verification
Input (English): Question: Are methylation alterations a major cause of PTTG1 misregulation?
Answer: Our data suggest that neither methylation alterations nor LOH are involved in PTTG1 over-expression. These data, together with those previously reported, point towards a post-transcriptional level of misregulation associated to PTTG1 over-expression.
Output (English): no