Task: Answer Verification
Input (English): Question: Does short-term oxycodone treatment affect electrogenic ion transport in isolated mucosa from the human rectosigmoid colon?
Answer: Compared to placebo, epithelial electrogenic ion transport is not altered in mucosal biopsies from the rectosigmoid colon following 5-d oxycodone treatment. The secretory mechanisms in isolated mucosa appear to play a negligible role in the development of opioid-induced constipation.
Output (English): no