Task: Answer Verification
Input (English): Question: Does the change in B-type natriuretic peptide levels over time predict significant rejection in cardiac transplant recipients?
Answer: There is a strong, graded relationship between the within-individual increase in NT-proBNP and the odds of significant rejection independent of hemodynamic parameters. These results suggest that the change in NT-proBNP rather than absolute BNP levels may offer a non-invasive approach to detect rejection.
Output (English): yes