Task: Answer Verification
Input (English): Question: Is circadian variation in serum cortisol during hydrocortisone replacement attributable to changes in cortisol-binding globulin concentrations?
Answer: Circadian variation in serum cortisol during hydrocortisone replacement is not attributable to changes in cortisol-binding globulin concentration. Changes in serum cortisol levels may thus be explained by other factors including 11 β-hydroxysteroid dehydrogenase type 1 activity or circadian changes in the binding properties of CBG.
Output (English): no