Task: Answer Verification
Input (English): Question: Does empiric , broad-spectrum antibiotic therapy with an aggressive de-escalation strategy induce gram-negative pathogen resistance in ventilator-associated pneumonia?
Answer: In our SICU, early, empiric broad-spectrum VAP therapy followed by de-escalation to pathogen-specific agents did not alter antimicrobial resistance and is a valid practice. Further, our compliance with de-escalation practices was higher than published rates.
Output (English): no