Task: Answer Verification
Input (English): Question: Is basal and β-adrenergic cardiomyocytes contractility dysfunction induced by dietary protein restriction associated with downregulation of SERCA2a expression and disturbance of endoplasmic reticulum Ca2+ regulation in rats?
Answer: The observations reveal that protein restriction induces marked myocardial morphofunctional damage. The pathological changes of cardiomyocyte mechanics suggest the potential involvement of the β-adrenergic system, which is possibly associated with changes in SERCA2a expression and disturbances in Ca(2+) intracellular kinetics.
Output (English): yes