Task: Answer Verification
Input (English): Question: Do amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer disease?
Answer: Clinically normal individuals who are APOE ε4+ and have high Aβ showed the highest cognitive decline. These results suggest that Aβ and APOE ε4 are not redundant contributors of decline in aging but rather interact to promote decline during the short follow-up period examined in this study. Longer follow-up periods will be essential to fully elucidate the influence of Alzheimer disease risk factors on cognitive decline in aging.
Output (English): yes