Task: Answer Verification
Input (English): Question: Does mast cell deficiency exacerbate inflammatory bowel symptoms in interleukin-10-deficient mice?
Answer: Mast cell deficiency in IL-10-deficient mice resulted in systematic and gut inflammation, impaired gut barrier function, and severer Th1-mediated colitis when compared to mice with only IL-10-deficiency. Inflammation and impaired gut epithelial barrier function likely form a vicious cycle to worsen colitis in the DKO mice.
Output (English): yes