Task: Answer Verification
Input (English): Question: Does the risk of coronary thrombosis with cyclo-oxygenase-2 inhibitors vary with polymorphisms in two regions of the cyclo-oxygenase-2 gene?
Answer: We found little evidence of a gene/drug interaction. We found a statistically non-significant trend toward a lower risk of coronary events with NSAIDs in the presence of the 'low risk' haplotype. Even if confirmed, the clinical utility of the finding would be limited as this haplotype is carried by a minority of the population.
Output (English): no