Task: Answer Verification
Input (English): Question: Does rate response and cardiac resynchronisation therapy in chronic heart failure : higher cardiac output acutely improve exercise performance : a pilot trial?
Answer: RAP resulted in a net increase in CO, without an acute favourable effect on exercise capacity. This finding underscores the importance of peripheral factors (endothelial and skeletal muscle dysfunction) as determinants of exercise capacity in CHF. The fact that longitudinal systolic myocardial velocities at higher HR did not change or even decreased suggests that a blunted FFR still occurs, despite CRT. RAP had no effect on mechanical synchrony.
Output (English): no