Task: Answer Verification
Input (English): Question: Is gene transfer in vitro and in vivo by cationic lipids significantly affected by levels of supercoiling of a reporter plasmid?
Answer: In considering a specification for the amount of supercoiled plasmid in a gene therapy product, it must be noted that the relaxed forms of the plasmid are no less efficient at gene delivery than the supercoiled forms.
Output (English): no