Task: Answer Verification
Input (English): Question: Is polymorphism in the epidermal growth factor gene associated with pre-eclampsia and low birthweight?
Answer: In this study we found further evidence for the association of polymorphism in the EGF gene with pre-eclampsia and the weight of babies at birth and identified rs3756261A>G as the SNP that makes the most significant contribution to this association. Bioinformatic analysis showed that this effect may be mediated by caudal type homeohox-2, a transcriptional repressor expressed in the trophoblast, for which a binding site is created at this polymorphic site when the rs3756261A allele is present.
Output (English): yes