Task: Answer Verification
Input (English): Question: Is methylation of the estrogen receptor-alpha gene promoter selectively increased in proliferating human aortic smooth muscle cells?
Answer: Our data support the concept that the genome of aortic smooth muscle cells is responsive to environmental conditions, and that DNA methylation, in particular methylation of the ERalpha, could contribute to the switch in phenotype observed in these cells.
Output (English): yes