Task: Answer Verification
Input (English): Question: Is the expression of Wnt-inhibitor DKK1 ( Dickkopf 1 ) determined by intercellular crosstalk and hypoxia in human malignant gliomas?
Answer: In this study, we showed for the first time that the expression of DKK1 was hypoxia dependent in human malignant glioma cell lines. The induction of DKK1 by intracellular crosstalk or hypoxia stimuli sheds light on the intense adaption of glial tumour cells to environmental alterations.
Output (English): yes