Task: Answer Verification
Input (English): Question: Are genetic polymorphisms of the serotonin transporter , but not the 2a receptor or nitric oxide synthetase , associated with pulmonary hypertension in chronic obstructive pulmonary disease?
Answer: In this COPD cohort we confirm that PH is frequent and usually mild, but out of proportion in a subgroup. We found a significant association of the L-allelic variant of 5HTT with PH overall and especially in out-of-proportion PH. These findings may point towards a role of the serotonin system in COPD-PH and warrant further studies.
Output (English): yes