Task: Answer Verification
Input (English): Question: Is down-regulation of sirtuin 3 associated with poor prognosis in hepatocellular carcinoma after resection?
Answer: Down-regulation of intratumoral and peritumoral Sirt3 were both associated with poor outcome in HCC, moreover, intratumoral Sirt3 was a favorable prognostic predictor in early stage patients.
Output (English): yes