Task: Answer Verification
Input (English): Question: Is fatigue in primary Sjögren 's syndrome associated with lower levels of proinflammatory cytokines?
Answer: Cytokines, pain and depression appear to be the most powerful predictors of fatigue in pSS. Our data challenge the notion that proinflammatory cytokines directly mediate fatigue in chronic immunological conditions. Instead, we hypothesise that mechanisms regulating inflammatory responses may be important.
Output (English): yes