Task: Answer Verification
Input (English): Question: Is integrin β-8 , but not β-5 or -6 , protein expression increased in livers of children with biliary atresia?
Answer: Our data show that integrin ανβ8, but not integrin ανβ5 or integrin ανβ6, protein expression is increased in liver specimens of patients with BA. These data support the mounting evidence that transforming growth factor-β (TGF-β) activation is responsible for the fibrosis found in BA. Anti-integrin ανβ8 or more global integrin blocking strategies may be therapeutic options in BA, but further work is clearly needed.
Output (English): yes