生化奇兵系列的音樂由1930年代、1940年代和1950年代的授權音樂，以及由創作的原創管弦樂配樂所組成。

生化奇兵

原創配樂 

《生化奇兵》的原創配樂由作曲。 一系列曲目曾透過官方2K Games網站以MP3格式於2007年8月24日免費發給粉絲。 但目前的鏈接是失效。

生化奇兵：管弦樂配樂（BioShock: Orchestral Score） 

 "Bioshock Main Theme (The Ocean on his Shoulders)" - 1:56
 "Welcome to Rapture" - 1:52
 "Dr. Steinman" - 1:00
 "The Docks" - 0:53
 "The Dash" - 0:35
 "Step into My Gardens" - 1:10
 "Dancers on a String" - 1:28
 "Cohen's Masterpiece" - 2:53
 "The Engine City" - 1:07
 "Empty Houses" - 1:43
 "This Is Where They Sleep" - 1:21
 "All Spliced Up" - 1:03

銷魂城之聲（Sounds of Rapture） 

一個原聲帶發布給德國消費者，包含與管弦樂配樂相同的所有曲目，但在歌曲之間加入遊戲中的配音，如安德魯·雷恩（Andrew Ryan）在遊戲開始時進入銷魂城的演講。

 "BioShock Main Theme (The Ocean on His Shoulders)" - 1:58
 "Andrew Ryan - Tauchfahrt" - 1:03
 "Welcome to Rapture" - 1:55
 "Andrew Ryan - Hohn" - 0:33
 "Dr. Steinman" - 1:02
 "Dr. Steinman - Schwester, Skalpell!" - 0:39
 "The Docks" - 0:55
 "Geist - Schönheit versprochen" - 0:16
 "The Dash" - 0:37
 "Atlas - Little Sisters" - 0:20
 "Step Into My Gardens" - 1:13
 "Dr. Suchang - Zarn-Versuch" - 0:38
 "Dancers on a String" - 1:31
 "Atlas - Die ganze Stadt geht zum Teufel" - 0:19
 "Cohen's Masterpiece" - 2:55
 "Martin Finnegan - Der Eismann kommt" - 0:49
 "The Engine City" - 1:10
 "Geist - Total verspliced" - 0:11
 "Empty Houses" - 1:46
 "Dr. Suchong - Bewussteinskontrolle" - 0:29
 "This Is Where They Sleep" - 1:23
 "Andrew Ryan - Natur der Dinge" - 0:18
 "All Spliced Up" - 1:04

我是銷魂城，銷魂城是我（I Am Rapture, Rapture Is Me） 

《生化奇兵》的整個音樂聲帶收錄在一張黑膠唱片上，並包含在《生化奇兵2》的特別版中。除了 "The Dash"，還有其他未發行的曲目以外，幾乎所有可下載的配樂曲目都有收錄。

已授權的原聲帶 

在玩家在《生化奇兵》中探索時，留聲機偶爾會播放來自1920年代至1960年代之间的音樂。

 "" - 金格·萊恩哈特 及 
 "If I Didn't Care" - 
 "The Party's Over Now" - 諾爾·克華德
 "" - 
 "" - 冰·哥羅士比
 "" - 金格·萊恩哈特 及 
 "" - 比莉·荷莉戴
 "" - 冰·哥羅士比
 "" - 安德魯斯姐妹
 "" - 金格·萊恩哈特
 "" - 比莉·荷莉戴
 "" - 金格·萊恩哈特 及 
  - 諾爾·克華德
 "" - 巴比·達林
 "Waltz of the Flowers" - 彼得·伊里奇·柴可夫斯基
 "" - 帕蒂·佩奇
 "It's Bad for Me" - 
 "" - 金格·萊恩哈特 及 
 "" - 佩里·科莫
 "" - 科爾·波特與 及 his Nighthawks
 "丹尼男孩" - 馬利奧·蘭沙

短暫出現的歌曲

 "The Ballroom Waltz" -  (Song that plays when Sander Cohen descends the steps after the player has completed his masterpiece)
 "And All the While I'm Loving You" -Essentials Jazz Masters (Background tune in "New Year's Eve Alone" audio diary)
 "" - / (Sung by the Waders Splicer)

在遊戲數據中但未被使用的歌曲

 "Wild Ride" - The Faux Frenchmen
 "" - 
 "" - 諾爾·克華德

在遊戲數據中但未被使用和無法播放的歌曲

 "Rosalie" -  及 His Orchestra
 "" - 比莉·荷莉戴
 "Jive at Five" - 
 "Happy Feet" - 凱伯·凱洛威
 "Lil' Darlin'" - 
 "" - 納·京·高爾

已授權但未被使用的歌曲

 "Avalon" - 金格·萊恩哈特 及 
 "" - 
 "Let's Fly Away" - 
 "This is a Changing World" - 諾爾·克華德
 "You're Getting to Be a Habit with Me" - 冰·哥羅士比/
 "Academy Award" - 

除了這些，由巴迪·瑞奇和演奏的歌曲""出現在PlayStation 3版本的遊戲安裝片段期間。

生化奇兵：迷你專輯（The BioShock EP） 

生化奇兵：迷你專輯（也稱為銷魂城：迷你專輯）是《生化奇兵》的限量版版本中包含的CD，並包含莫比和Oscar the Punk混音。CD上的三個混音曲目包括有""、""和"Wild Little Sisters"。這些歌曲的原始錄音是在遊戲中。

生化奇兵2

原創配樂 

《生化奇兵2》的原創配樂由加里·席曼作曲。它是以名稱「來自燈塔的聲音」（Sounds From The Lighthouse (Official BioShock 2 Score)）於2010年2月9日放在遊戲特別版內的CD上發售。本配樂共有來自遊戲中的26條曲目。

Sounds From The Lighthouse

已授權的原聲帶 

在《生化奇兵2》中已授權的音樂以Amazon MP3和CD專輯形式在2010年4月15日正式發行，標題為「生化奇兵2：官方原聲帶（特別版）」（Bioshock 2: The Official Soundtrack - Music From And Inspired By The Game (Special Edition)）。包含18首曲目，全長52分鐘。

官方原聲帶 

 "The Boogie Man - Todd Rollins & His Orchestra with Chick Bullock" - 3:03
 (How Much Is) That Doggie in the Window? - 帕蒂·佩奇 - 2:38
 Twentieth Century Blues - 諾爾·克華德 - 3:34
 Nightmare - 亞提·蕭 及 His New Music - 2:49
 Daddy, Won't You Please Come Home? - Annette Hanshaw - 2:58
 Praise the Lord and Pass the Ammunition - Kay Kyser & His Orchestra - 2:32
 Dawn of a New Day - Horace Heidt & His Musical Knights - 2:30
 Night and Day - 比莉·荷莉戴 及 Her Orchestra - 2:58
 My Heart Belongs to Daddy - Eddy Duchin & His Orchestra, featuring Mary Martin - 2:54
 Chasing Shadows - 金格·萊恩哈特 及 Stéphane Grappelli - 2:57
 Jitterbug Waltz - Fats Waller & His Rhythm - 3:20
 I Cover the Waterfront - Connee Boswell - 2:57

官方原聲帶（特別版） 

 "The Boogie Man - Todd Rollins & His Orchestra with Chick Bullock" - 3:03
 (How Much Is) That Doggie in the Window? - 帕蒂·佩奇 - 2:38
 Twentieth Century Blues - 諾爾·克華德 - 3:34
 Nightmare - 亞提·蕭 及 His New Music - 2:49
 Daddy, Won't You Please Come Home? - Annette Hanshaw - 2:58
 Praise the Lord and Pass the Ammunition - Kay Kyser And His Orchestra - 2:32
 Dawn of a New Day - Horace Heidt And His Musical Knights - 2:30
 Night and Day - 比莉·荷莉戴 及 Her Orchestra - 2:58
 My Heart Belongs to Daddy - Eddy Duchin & His Orchestra, featuring Mary Martin - 2:54
 Chasing Shadows - 金格·萊恩哈特 及 Stéphane Grappelli - 2:57
 Jitterbug Waltz - Fats Waller & His Rhythm - 3:20
 I Cover the Waterfront - Connie Boswell - 2:57
 Mental Strain at Dawn - Jack Purvis - 2:46
 Bei Mir Bist Du Schön - Benny Goodman & His Orchestra, with vocal by Martha Tilton - 2:32
 The Trouble with Me Is You -  - 2:32
 The Skeleton in the Closet -  - 2:33
 We Saw the Sea - 佛烈·雅士提 - 2:19
 La Mer - 金格·萊恩哈特 及 Stéphane Grappelli - 4:16

遊戲中已授權的音樂 

 "Hush, Hush, Hush, Here Comes the Bogeyman" - Henry Hall & His Orchestra
 "You Always Hurt the One You Love" - The Mills Brothers
 "(How Much Is) That Doggie in the Window?" - Patti Page
 "Nightmare" - Artie Shaw & His New Music
 "Sweet Madness" - Adrian Rollini & His Orchestra, including Benny Goodman, Bunny Berigan, etc.
 "Daddy, Won't You Please Come Home?" - Annette Hanshaw
 "Bei Mir Bist Du Schön" - Benny Goodman & His Orchestra, with vocal by Martha Tilton
 "Bei Mir Bist Du Schön" - The Andrews Sisters
 "The Boogie Man" - Todd Rollins & His Orchestra with Chick Bullock
 "Twentieth Century Blues" - Noël Coward
 "Praise the Lord and Pass the Ammunition" - Kay Kyser & His Orchestra
 "Dawn of a New Day" - Horace Heidt & His Musical Knights
 "Night and Day" - Billie Holiday & Her Orchestra
 "My Heart Belongs to Daddy" - Eddy Duchin & His Orchestra, featuring Mary Martin
 "Chasing Shadows" - Django Reinhardt & Stéphane Grappelli
 "Jitterbug Waltz" - Fats Waller & His Rhythm
 "I Cover the Waterfront" - Connee Boswell
 "Mental Strain at Dawn" - Jack Purvis, trumpet solo, with rhythm accompaniment
 "We Three (My Echo, My Shadow, and Me)" - The Ink Spots
 "I'm Making Believe" - The Ink Spots with Ella Fitzgerald
 "It's Only a Paper Moon" - Ella Fitzgerald
 "Nobody Knows You When You're Down and Out" - Bessie Smith
 "Pennies from Heaven" - Bing Crosby
 "Paper Doll" - The Mills Brothers
 "Ten Cents a Dance" - Ruth Etting
 "Need a Little Sugar in My Bowl" - Bessie Smith
 "Memories of You" - The Ink Spots
 "The Devil and the Deep Blue Sea" - Cab Calloway
 "Daddy's Little Girl" - The Mills Brothers
 "Liza (All the Clouds'll Roll Away)" - Django Reinhardt & Stéphane Grappelli
 "Someone's Rocking My Dreamboat" - The Ink Spots
 "It's Bad for Me" - Rosemary Clooney
 "It Had to be You" - Django Reinhardt & Stéphane Grappelli
 "Dream" - The Pied Pipers

銷魂城收音機（網上廣告廣播）上的歌曲但已從最終版本中移除：

 "The Wreck of the Old Southern 97" - Ernest Thompson
 "All by Myself" - Aileen Stanley
 "Delilah Jones" - McGuire Sisters
 "Crazy Blues" - Mary Stafford
 "I'm Gonna Jazz My Way" - Mary Stafford
 "Struttin Blues" - Leona Williams
 "Across the Alley from the Alamo" - The Mills Brothers
 "Civilization" - Danny Kaye & The Andrew Sisters
 "Who Cares?" - Eddie Elkins Orchestra
 "Who Dat Up Dere" - Woody Herman
 "St. James Infirmary Blues" - Spike Hughes & His Dance Orchestra
 "Sally Goodin" - Obed Pickard
 "Hey! Ba-Ba-Re-Bop" - Lionel Hampton
 "Put 'em in a Box, Tie 'em with a Ribbon, and Throw 'em in the Deep Blue Sea" - Danny Kaye & The Andrew Sisters

除此之外，由所唱的歌曲""曾在《生化奇兵2》的前導預告片中播放。

由Annette Hanshaw所唱的歌曲"Daddy, Won't You Please Come Home?"被用於預告片中，它也可以在遊戲的早期關卡之一聽到。

生化奇兵：無限之城

原創配樂 

《生化奇兵：無限之城》的原創配樂由加里·席曼作曲。它是獨家包含在限量的高級版（Premium Edition）和鳴鳥版（Songbird Edition），以數位形式下載。

生化奇兵：無限之城（原聲帶） 

所有曲目都是由加里·席曼作曲，除了另有說明之外。

已授權的原聲帶 

一些加入在《生化奇兵：無限之城》中的音樂以MP3專輯，和隨選服務專輯於2013年2月1日非正式發行，標題為「被揭露的原創歌曲」（The Original Songs Uncovered (Tracks Inspired By Bioshock Infinite)）。包含12首曲目，全長33:49分鐘。

被揭露的原創歌曲（The Original Songs Uncovered） 

 "Can the Circle Be Unbroken" - The Carter Family
 "Give Me That Old Time Religion" - Jane Russell, Connie Haines, Rhonda Fleming
 "It All Depends On You" - Ruth Etting
 "Ain't She Sweet" - Jimmie Lunceford
 "Goodnight, Irene" - Lead Belly
 "You're a Grand Old Flag" - Billy Murray
 "Makin' Whoopee" - Eddie Cantor
 "After You've Gone" - Ruth Etting
 "I'm Forever Blowing Bubbles" - The Merry Macs
 "The Clouds Will Soon Roll By" - Ambrose and his Orchestra
 "Liza (All the Clouds'll Roll Away)" - Al Jolson
 "Behind the Clouds" - Joe Loss & His Orchestra, Elizabeth Batey, Howard Jones

遊戲中已授權的音樂 

 "Old-Time Religion" - Polk Miller
 "St. James Infirmary Blues" - Duke Ellington & His Orchestra
 "Button Up Your Overcoat" - Helen Kane
 "Goodnight, Irene" - performed by Bill Lobley
 "Just a Closer Walk with Thee" - performed by Courtnee Draper
 "Dew-Dew-Dewey Day" - Charles Kaley & His Orchestra
 "Shine On, Harvest Moon" - Ada Jones and Billy Murray
 "Me and My Shadow" - Sam Lanin Orchestra
 "I'm Wild About That Thing" - Bessie Smith
 "Wild Prairie Rose" - performed by Jessy Carolina, Ommie Wise
 "Ain't She Sweet" - Ben Bernie & His Orchestra, with Scrappy Lambent and Billy Hillpot
 "Shake Sugaree" - Elizabeth Cotten and Brenda Evans
 "Ain't We Got Fun" - Van and Schenck
 "The Bonnie Blue Flag" - Polk Miller
 D小调安魂弥撒曲-沃尔夫冈·阿马德乌斯·莫扎特
 "继抒咏 赫赫君王"
 "继抒咏 受判之徒"
 "继抒咏 流泪之日"
 "羔羊赞"
 G弦上的咏叹调-约翰·塞巴斯蒂安·巴赫
 夜想曲第9号第2番-弗雷德里克·肖邦
 感伤华尔兹第1号-弗朗茨·舒伯特，演奏者杜康·瓦特
 "Canon in D major" - Johann Pachelbel
 "Bridal Chorus" - Richard Wagner
 "Solace" - Scott Joplin, performed by Duncan Watt (Loading Screen BioShock Infinite)
 "Will the Circle Be Unbroken?" - performed by Courtnee Draper and Troy Baker
 "Will the Circle Be Unbroken?" (Choir) - performed by Maureen Murphy
 "Indian Love Call" - Sigmund Krumgold
 "Little Pal" - Lew White
 "Watermelon Party" - Polk Miller
 "Makin' Whoopee - Rudy Vallée
 "Black Gal" - Ed Lewis with Alan Lomax
 "It All Depends on You" - Irving Kaufman with Fred Rich Orchestra
 "You're a Grand Old Flag - Billy Murray
 "La Mer" - Django Reinhardt & Stéphane Grappelli
 "Beast" – Nico Vega (appears during game's demonstration mode)

時代不合的翻唱 

 "After You've Gone" - performed by Jessy Carolina
 "God Only Knows" - The Beach Boys
 "God Only Knows" - The Barbershop Quartet
 "Girls Just Want to Have Fun" - Cyndi Lauper
 "Girls Just Want to Have Fun (instrumental)" - arranged by Jim Bonney
 "Tainted Love" - Gloria Jones
 "Tainted Love (Blues Version)" - arranged by Scott Bradlee, lead vocal by Miche Braden
 "Fortunate Son" - Creedence Clearwater Revival
 "Fortunate Son (a cappella version)" - performed by Jessy Carolina
 "Shiny Happy People" - R.E.M.
 "Shiny Happy People (1912 version)" - arranged by Scott Bradlee, lead vocal by Tony Babino
 "Everybody Wants to Rule the World" - Tears for Fears
 "Everybody Wants to Rule The World (waltz cover)" - arranged by Scott Bradlee

預告片曲目

 "Fury Oh Fury" - Nico Vega

海葬原聲帶（Burial at Sea soundtrack） 

《》的原聲帶由已授權的音樂，還有加里·席曼作曲的原創配樂所組成。

第一章

 "Wonderful! Wonderful!" - Johnny Mathis
 "The Lady Is a Tramp" - Mel Tormé
 "She's Got You" - Patsy Cline
 "La Mer" - Django Reinhardt & Stéphane Grappelli
 "Waltz of the Flowers" (accordion version) - Pyotr Ilyich Tchaikovsky
 "Cohen's Masterpiece" (accordion version) - Garry Schyman
 "Tonight for Sure!" - Ruth Wallis
 "It Had to Be You" - Django Reinhardt & Stéphane Grappelli
 "Midnight, the Stars and You" - Ray Noble & His Orchestra with Al Bowlly
 "Nocturne, Op. 9" - Frédéric Chopin
 "Little Pal" - Lew White
 "Polovtsian Dances" - Alexander Borodin
 "Good King Wenceslas" - performed by Duncan Watt
 "Bridal Chorus" - Richard Wagner
 "Wedding March - Felix Mendelssohn

第二章

 "La Vie en rose" - Édith Piaf
 "You Belong to Me" - Courtnee Draper
 "Row, Row, Row Your Boat" - Jennifer Hale, Oliver Vaquer
 "Nocturne, Op. 9" - Frédéric Chopin
 "Easy to Love" - Sammy Davis Jr.
 "Don't Sit Under the Apple Tree (With Anyone Else but Me)" - Glenn Miller Orchestra
 "Canon in D major - Johann Pachelbel
 "Rise, Rapture, Rise" - Ken Levine
 "The Great Pretender" - The Platters
 "Back In Baby's Arms" - Patsy Cline
 "La Mer" - Django Reinhardt & Stéphane Grappelli

參考資料 

生化奇兵系列
BioShock