Anchor: There are inherent differences between the use of a NOEC or LOEC derived from hypothesis testing to estimate a safe concentration, and the use of a LC, EC, IC, or other point estimates derived from curve fitting, interpolation, etc.
Entailed: There is a significant difference between a NOEC or LOEC and a LC, EC, IC, or other point estimates. 
Contradiction: LC, EC, IC, and other point estimates are derived from hypothesis testing.
Contradiction: An extraordinary man does not hunger for or pursue the power to change the world.
Contradiction: Celebrity down falls are very prevalent in the last thirty or so days.
Contradiction: Financial ruin never managed to plague Poland.
Contradiction: People are outdoors.