Anchor: To determine the best of the available screens, a multi-center trial with a broad demographic mix and a large number of patients subjected to different screens is needed.
Entailed: A multi-center trial with a broad demographic mix and a large number of patients subjected to different screens is needed.
Contradiction: A multi-center trial is not needed to determine the best of the available screens.
Contradiction: The girl is in the middle of the road.
Contradiction: IPM helped develop the proposal.
Contradiction: He was convinced of the person's guilt from the beginning. 
Contradiction: Viriathus was assassinated in 139 b.c.