Detailed Data Number of Intractable Disease Medical Treatment Recipient Certificates Issued

Disease No.	Disease	Date of implementation	Number of certificates issued
1	Behcet's disease	April, 1972	17,290
2	Multiple sclerosis (MS)	April, 1973	14,492
3	Myasthenia gravis	April, 1972	17,314
4	Systemic lupus erythematosus (SLE)	same as above	56,254
5	Subacute myelo-optico-neuropathy (SMON)	same as above	1,628
6	Aplastic anemia	April, 1973	9,417
7	Sarcoidosis	October, 1974	20,268
8	Amyotrophic lateral sclerosis (ALS)	same as above	8,406
9	Scleroderma, dermatomyositis, and polymyositis	same as above	42,233
10	Idiopathic thrombocytopenic purpura (ITP)	same as above	22,220
11	Polyarteritis nodosa	October, 1975	7,600
12	Ulcerative colitis	same as above	117,855
13	Aortitis syndrome	same as above	5,438
14	Buerger's disease	same as above	7,147
15	Pemphigus	same as above	4,648
16	Spinocerebellar ataxia	October, 1976	23,290
17	Crohn's disease	same as above	31,652
18	Fulminant hepatic failure	same as above	210
19	Malignant rheumatoid arthritis	October, 1977	5,891
20	Parkinsonian disorder	106,637
[1]	Progressive supranuclear palsy	October, 2003
[2]	Corticobasal degeneration	October, 2003
[3]	Parkinson's disease	October, 1978
21	Amyloidosis	October, 1979	1,505
22	Ossification of posterior longitudinal ligament	December, 1980	29,647
23	Huntington's disease	October, 1981	798
24	Moyamoya disease (Occlusive disease in circle of Willis)	October, 1982	12,992
25	Wegener's granulomatosis	January, 1984	1,671
26	Idiopathic dilated (congestive) cardiomyopathy	January, 1985	22,123
27	Multiple system atrophy	11,096
[1]	Striatonigral degeneration	October, 2003
[2]	Olivopontocerebellar atrophy	October, 1976
[3]	Shy-Drager syndrome	January, 1986
28	Epidermolysis bullosa (junctional or dystrophic)	January, 1987	315
29	Pustular psoriasis	January, 1988	1,679
30	Spinal stenosis	January, 1989	4,218
31	Primary biliary cirrhosis	January, 1990	17,298
32	Severe acute pancreatitis	January, 1991	1,132
33	Idiopathic necrosis in femur head	January, 1992	13,476
34	Mixed connective tissue disease	January, 1993	9,028
35	Primary immunodeficiency syndrome	January, 1994	1,147
36	Idiopathic interstitial pneumonia	January, 1995	5,896
37	Pigmentary degeneration of the retina	January, 1996	25,296
38	Prion disease	Unified in June, 2002	492
[1]	Creutzfeldt-Jakob disease	January, 1997
[2]	Gerstmann-Straussler-Scheinker disease	June, 2002
[3]	Fatal familial insomnia	June, 2002
39	Primary pulmonary hypertension	January, 1998	1,560
40	Neurofibromatosis	May, 1998	3,112
41	Subacute sclerosing panencephalitis	December, 1998	87
42	Budd-Chiari syndrome	same as above	232
43	Idiopathic chronic pulmonary thromboembolism (pulmonary hypertensive)	same as above	1,288
44	Lysosomal storage disease	Unified in June, 2002	760
[1]	Fabry's disease	April, 1999
[2]	Lysosomal storage disease	May, 2001
45	Adrenoleukodystrophy	April, 2000	173
46	Familial hypercholesterolemia (homozygote)	October, 2009	120
47	Spinal muscular atrophy	October, 2009	514
48	Spinobulbar muscular atrophy	October, 2009	686
49	Chronic inflammatory demyelinating polyradiculoneuropathy	October, 2009	2,328
50	Hypertrophic cardiomyopathy	October, 2009	2,239
51	Restrictive cardiomyopathy	October, 2009	18
52	Mitochondrial disease	October, 2009	764
53	Lymphangioleiomyomatosis (LAM)	October, 2009	335
54	Severe erythema exudativum multiforme (acute phase)	October, 2009	48
55	Ossification of ligamentum flavum	October, 2009	993
56	Pituitary dysfunction (PRL secretion abnormality, gonadotropin secretion abnormality, ADH secretion abnormality, hypophyseal TSH secretion abnormality, Cushing's disease, acromegaly, hypopituitarism)	October, 2009	11,764
Total	706,720

(Note) Miyagi and Fukushima Prefectures are not included due to the impact of the Great East Japan Earthquake.

* Source: Report on Public Health Administration and Services

$ ^{*} $ Subjected diseases listed above are as of April 1, 2010.