Detailed Data Number of Intractable Disease Medical Treatment Recipient Certificates Issued

Disease No.	Disease	Date of implementation	Number of certificates issued
1	Behcet's disease	April, 1972	18,636
2	Multiple sclerosis (MS)	April, 1973	17,073
3	Myasthenia gravis	April, 1972	19,670
4	Systemic lupus erythematosus (SLE)	same as above	60,122
5	Subacute myelo-optico-neuropathy (SMON)	same as above	1,524
6	Aplastic anemia	April, 1973	10,287
7	Sarcoidosis	October, 1974	23,088
8	Amyotrophic lateral sclerosis (ALS)	same as above	9,096
9	Scleroderma, dermatomyositis, and polymyositis	same as above	47,310
10	Idiopathic thrombocytopenic purpura (ITP)	same as above	24,100
11	Polyarteritis nodosa	October, 1975	9,610
12	Ulcerative colitis	same as above	143,733
13	Aortitis syndrome	same as above	5,881
14	Buerger's disease	same as above	7,109
15	Pemphigus	same as above	5,279
16	Spinocerebellar ataxia	October, 1976	25,447
17	Crohn's disease	same as above	36,418
18	Fulminant hepatic failure	same as above	266
19	Malignant rheumatoid arthritis	October, 1977	6,255
20	Parkinsonian disorder	120,406
[1]	Progressive supranuclear palsy	October, 2003
[2]	Corticobasal degeneration	same as above
[3]	Parkinson's disease	October, 1978
21	Amyloidosis	October, 1979	1,802
22	Ossification of posterior longitudinal ligament	December, 1980	33,346
23	Huntington's disease	October, 1981	851
24	Moyamoya disease (Occlusive disease in circle of Willis)	October, 1982	15,177
25	Wegener's granulomatosis	January, 1984	1,942
26	Idiopathic dilated (congestive) cardiomyopathy	January, 1985	25,233
27	Multiple system atrophy	11,733
[1]	Striatonigral degeneration	October, 2003
[2]	Olivopontocerebellar atrophy	October, 1976
[3]	Shy-Drager syndrome	January, 1986
28	Epidermolysis bullosa (junctional or dystrophic)	January, 1987	347
29	Pustular psoriasis	January, 1988	1,843
30	Spinal stenosis	January, 1989	5,147
31	Primary biliary cirrhosis	January, 1990	19,701
32	Severe acute pancreatitis	January, 1991	1,664
33	Idiopathic necrosis in femur head	January, 1992	15,388
34	Mixed connective tissue disease	January, 1993	10,146
35	Primary immunodeficiency syndrome	January, 1994	1,383
36	Idiopathic interstitial pneumonia	January, 1995	7,367
37	Pigmentary degeneration of the retina	January, 1996	27,158
38	Prion disease	Unified in June, 2002	475
[1]	Creutzfeldt-Jakob disease	January, 1997
[2]	Gerstmann-Straussler-Scheinker disease	June, 2002
[3]	Fatal familial insomnia	same as above
39	Primary pulmonary hypertension	January, 1998	2,299
40	Neurofibromatosis	May, 1998	3,588
41	Subacute sclerosing panencephalitis	December, 1998	83
42	Budd-Chiari syndrome	same as above	252
43	Idiopathic chronic pulmonary thromboembolism (pulmonary hypertensive)	same as above	1,810
44	Lysosomal storage disease	Unified in June, 2002	911
[1]	Fabry's disease	April, 1999
[2]	Lysosomal storage disease	May, 2001
45	Adrenoleukodystrophy	April, 2000	193
46	Familial hypercholesterolemia (homozygote)	October, 2009	140
47	Spinal muscular atrophy	same as above	712
48	Spinobulbar muscular atrophy	same as above	960
49	Chronic inflammatory demyelinating polyradiculoneuropathy	same as above	3,423
50	Hypertrophic cardiomyopathy	same as above	3,144
51	Restrictive cardiomyopathy	same as above	24
52	Mitochondrial disease	same as above	1,087
53	Lymphangioleiomyomatosis (LAM)	same as above	526
54	Severe erythema exudativum multiforme (acute phase)	same as above	59
55	Ossification of ligamentum flavum	same as above	2,360
56	Pituitary dysfunction (PRL secretion abnormality, gonadotropin secretion abnormality, ADH secretion abnormality, hypophyseal TSH secretion abnormality, Cushing's disease, acromegaly, hypopituitarism)	same as above	17,069
Total	810,653

Source: Report on Public Health Administration and Services

As of the end of FY2012