Detailed Data Number of Intractable Disease Medical Treatment Recipient Certificates Issued

Disease No.	Disease	Date of implementation	Number of certificates issued
1	Behcet's disease	April, 1972	18,451
2	Multiple sclerosis (MS)	April, 1973	16,140
3	Myasthenia gravis	April, 1972	19,009
4	Systemic lupus erythematosus (SLE)	same as above	59,553
5	Subacute myelo-optico-neuropathy (SMON)	same as above	1,608
6	Aplastic anemia	April, 1973	10,148
7	Sarcoidosis	October, 1974	22,161
8	Amyotrophic lateral sclerosis (ALS)	same as above	8,992
9	Scleroderma, dermatomyositis, and polymyositis	same as above	45,833
10	Idiopathic thrombocytopenic purpura (ITP)	same as above	23,791
11	Polyarteritis nodosa	October, 1975	8,928
12	Ulcerative colitis	same as above	133,543
13	Aortitis syndrome	same as above	5,829
14	Buerger's disease	same as above	7,282
15	Pemphigus	same as above	5,085
16	Spinocerebellar ataxia	October, 1976	25,047
17	Crohn's disease	same as above	34,721
18	Fulminant hepatic failure	same as above	249
19	Malignant rheumatoid arthritis	October, 1977	6,302
20	Parkinsonian disorder	116,536
[1]	Progressive supranuclear palsy	October, 2003
[2]	Corticobasal degeneration	same as above
[3]	Parkinson's disease	October, 1978
21	Amyloidosis	October, 1979	1,736
22	Ossification of posterior longitudinal ligament	December, 1980	32,043
23	Huntington's disease	October, 1981	846
24	Moyamoya disease (Occlusive disease in circle of Willis)	October, 1982	14,465
25	Wegener's granulomatosis	January, 1984	1,834
26	Idiopathic dilated (congestive) cardiomyopathy	January, 1985	24,386
27	Multiple system atrophy	11,797
[1]	Striatonigral degeneration	October, 2003
[2]	Olivopontocerebellar atrophy	October, 1976
[3]	Shy-Drager syndrome	January, 1986
28	Epidermolysis bullosa (junctional or dystrophic)	January, 1987	338
29	Pustular psoriasis	January, 1988	1,823
30	Spinal stenosis	January, 1989	4,741
31	Primary biliary cirrhosis	January, 1990	19,054
32	Severe acute pancreatitis	January, 1991	1,587
33	Idiopathic necrosis in femur head	January, 1992	14,680
34	Mixed connective tissue disease	January, 1993	9,939
35	Primary immunodeficiency syndrome	January, 1994	1,286
36	Idiopathic interstitial pneumonia	January, 1995	7,065
37	Pigmentary degeneration of the retina	January, 1996	26,934
38	Prion disease	Unified in June, 2002	506
[1]	Creutzfeldt-Jakob disease	January, 1997
[2]	Gerstmann-Straussler-Scheinker disease	June, 2002
[3]	Fatal familial insomnia	same as above
39	Primary pulmonary hypertension	January, 1998	1,969
40	Neurofibromatosis	May, 1998	3,414
41	Subacute sclerosing panencephalitis	December, 1998	91
42	Budd-Chiari syndrome	same as above	261
43	Idiopathic chronic pulmonary thromboembolism (pulmonary hypertensive)	same as above	1,590
44	Lysosomal storage disease	Unified in June, 2002	868
[1]	Fabry's disease	April, 1999
[2]	Lysosomal storage disease	May, 2001
45	Adrenoleukodystrophy	April, 2000	187
46	Familial hypercholesterolemia (homozygote)	October, 2009	141
47	Spinal muscular atrophy	same as above	619
48	Spinobulbar muscular atrophy	same as above	888
49	Chronic inflammatory demyelinating polyradiculoneuropathy	same as above	2,986
50	Hypertrophic cardiomyopathy	same as above	2,779
51	Restrictive cardiomyopathy	same as above	26
52	Mitochondrial disease	same as above	945
53	Lymphangioleiomyomatosis (LAM)	same as above	439
54	Severe erythema exudativum multiforme (acute phase)	same as above	58
55	Ossification of ligamentum flavum	same as above	1,632
56	Pituitary dysfunction (PRL secretion abnormality, gonadotropin secretion abnormality, ADH secretion abnormality, hypophyseal TSH secretion abnormality, Cushing's disease, acromegaly, hypopituitarism)	same as above	15,017
Total	778,178

Source: Report on Public Health Administration and Services

As of the end of FY2011