Product review (4 stars): Took some effort, but does quite nicely
First, you'll need to adjust the thermostat beyond what the knob will allow. Google 'krs-2100 thermostat' and you'll find step by step instructions.
Second, you'll want to splice in a longer beverage line. Older models ran a too large diameter line. The beverage line on this is 3/16" which is what you want, but is only 5'. You'll want to get yourself a line splice (about $1) and another 5' length of 3/16" beverage line along with a couple hose clamps (probably $10).
Third, if you are homebrewing to a Corny keg, you'll need a conversion kit for either ball value (preferred) or pin lock disconnection. WARNING: every conversion kit I've seen will result in a commercial 1/6 keg no longer being able to stand upright inside the keg compartment. You WILL be able to get it to fit with the d-system coupler no problem, but with the conversion kit will have to tilt it, which will result in you not being able to cool another keg in there. It's ok for me, because I have a spare fridge where I can keep a back up corny of homebrew while I'm serving a commercial tap, but others might be frustrated.
Finally, as other's have said, keep the PSI way down (3-5psi) or the first few beers will be catastrophically foamy ON EVERY SESSION, not just for the keg.

By the way, it'll cost you $100 for your own corny keg, $40 for the equipment to homebrew, $30 for a conversion kit, and $30 for a recipe kit, so home brewing will result in weird tasting beer that you paid a lot of money for your first keg out. However, by your 4th keg, you'll have figured out how to get a decent brew, and going forward you'll be paying $30 for 5 gallons of high quality beer which beats the hell out of paying the $80 I have to pay locally for a 1/6th keg (plus deposit) of some mediocre commercial beer. For me, definitely worth the time and investment.

In the end, I dig this kegerator a lot. I plan on brewing some home made hard cider to try to get the wife to appreciate it next fall!