Paniponi Dash!
English name: Pani Poni Dash!
Genres: Comedy
Type: TV, Episodes: 26
Aired: Jul 4, 2005 to Dec 26, 2005
Studio: Shaft
Source: Manga
Rating: PG-13 - Teens 13 or older
Synopsis:
The 11-year-old Miyamoto Rebecca becomes the new teacher of a classroom which is full of weirdos. Despite her cute looks she's a little beast and can be pretty sarcastic and offensive. The school is not safe anymore now that she's in charge of a class and her students, Himeko, Ichijou, Rei and a white rabbit who took a liking to Rebecca help her to rough up the school and the neighbor with its teacher "ojii-chan."

(Source: ANN)