Wagaya no Oinari-sama.
English name: Our Home's Fox Deity
Genres: Comedy, Fantasy
Type: TV, Episodes: 24
Aired: Apr 7, 2008 to Sep 15, 2008
Studio: Zexcs
Source: Light novel
Rating: PG-13 - Teens 13 or older
Synopsis:
The Mizuchi bloodline has long been hunted by Yokai, or monsters. Toru and Noboru Takagami are descendents of this bloodline, and under their grandmother's discretion, are given a secret weapon to combat these monsters. It is Tenko Kugen, a fox deity who can take the shape of a man or woman at will. The mischievous deity is accompanied by a shrine maiden, Ko, who will both live with the Takagami brothers at their house. Life just got complicated. 

(Source: NIS America)