just pick one answer 

 Which is true about channel protein?  
A. It is a peripheral protein that changes its conformation to allow large molecules to pass 
through the membrane. 
B. It is a peripheral protein that forma a hole that allows charged and small substances to pass 
through the membrane. 
C. It is an integral protein that changes its conformation to allow large molecules to pass 
through the membrane. 
D. It is an integral protein that forma a hole that allows charged and small substances to pass 
through the membrane.