Forensic Science plays a very important part in the judicial system of any Country. Being an applied science, it is imperative to have a strong foundation in the natural sciences and also the development of practical skills in the application of these sciences to a particular discipline. Examination, analysis, interpretation, reporting, and testimonial support of physical evidence, being an essential part of Forensic Science, a Forensic scientist must be adept at incorporating knowledge and skills required in these jobs. 1 Since, eyewitness accounts could be compromised in truth or biased because of any number of reasons; physical evidence has gained enormous importance in criminal investigations during the past few decades. Physical evidence comprising elements like DNA, fingerprints, and trace evidence is capable of independently and objectively linking a suspect/victim to a crime, disproving an alibi, or develop important investigative leads. Not only nailing the offender, physical evidence can also save the innocent, disproving the charges leveled against him. 2 The most important stages of physical evidence examination are the initial stages. 3 If conducted properly, they prove to be decisive in the successful resolution of criminal investigations. The recognition, collection, and preservation of physical evidence, such as DNA, should be done properly as these have been rigorously scrutinized and challenged in court. 4 The advancement of applying DNA typing methods to Forensic application over the past decade and half is a major one in the examination of biological evidence. Due to its astonishing sensitivity and power of discrimination, DNA analysis has become a critical part of forensic science, forensic medicine and anthropology and in solving cases of paternity disputes. The physical evidence commonly submitted to forensic science laboratories for examination varies drastically. 5 In the early days, DNA analysis could be suitably conducted only from evidence that had some biological substances having nucleated cells. This constraint has now been dispensed within the last few years with the invention of mitochondrial DNA sequencing in the forensic arena. Now, DNA is successfully isolated and typed from common biological specimens such as bones, blood and bloodstains, semen and seminal stains, tissues, organs, teeth, hairs, fingernails, saliva, urine, and other biological fluids. 6 Only the quantity of DNA extracted varies. An important point to note is that compared to laboratory conditions, crime scene samples may contain significantly less usable amount of DNA depending upon the prevailing environmental conditions. Gastric fluids and fecal stains can also give DNA strains but it can prove difficult to generate a complete profile from these samples due to significant degradation. 7 Several factors affect the ability to obtain a DNA profile. The first and the foremost factor is sample quantity. Polymerase chain reaction- based (PCR) DNA typing methods are efficient and their sensitivity is noteworthy, but still limited. The second issue of concern is sample degradation. Even a substantially large blood stain exposed for a prolonged period of time