Introduction The sphere of nursing undergoes several changes, improvements, and evaluations constantly. Many professional researchers offer their own ideas and suggestions on how it is possible to optimize the system and provide patients with appropriate treatment and care. In this article, certain attention is paid to evidence-based research (EBR) in nursing practice, several particular sources of evidence, and ethical issues which may be aroused in nursing practice. EBR is considered to be a powerful step for many current and future nurses to realize how it is possible to manage various health problems of patients and prove that nursing care corresponds to special standards and expectations (Dickson & Flynn, 2008). For current EBR, four different sources are evaluated as well as personal communications with parents who have brought their children to the clinic to solve the problems caused by acute otitis media. Evaluation of watchful waiting is another important aspect that has to be taken into consideration in this paper. Some clinical guidelines admit that this kind of attitude to patients is more effective in comparison to immediately beginning treatment. It is not always correct to provide children with some treatment in order to do something. This is why a particular group of nurses finds the ideas of evidence-based research more appropriate for this practice and try to prove that the chosen methods should properly influence a child’s condition considering such crucial ethical issues like confidentiality, vulnerable population, and informed consent of parents. Evidence-based research in nursing practice is a new tendency that has to support and improved from time to time to help patients be confident in the care provided and in a healthy future for them. Evaluation of the chosen sources of evidence The theme of the chosen evidence-based research is children with acute otitis media and the decision to use watchful waiting to provide patients with appropriate treatment or to start treatment with antibiotics immediately. There are five sources of evidence chosen for this project. Each source introduces a separate attitude to the problem of acute otitis media in children; the diversity of suggestions should help to define what kind of treatment is more appropriate in this case and how it is better to implement new ideas into the already established system. The nurses brought sources of evidence of different types for their first meeting. One online source, two articles from Pediatric Infectious Journal, the chapter from the book by Hay, Levin, Sondheimer, and Deterding, and personal communications with parents are considered to be the sources of evidence for the nursing situation where children with acute otitis media have to be treated. Classification of sources by information type The first source under analysis is the American Academy of Pediatrics and the American Academy of Family Physicians from the Clinical Practice Guideline. This source of evidence contains reliable and educative information about treatment to children with acute otitis media (AOM) that is defined as a common infection that is characterized by antibacterial agents (Clinical Practice Guideline, 2004). The authors find it possible to use the already achieved results by other researchers as