The paper presents the analysis and evaluation of an article by Ware, Wang, Shapiro, and Collet (2015) that is devoted to the safety of using medicinal marijuana for pain management in adult non-cancer patients. As is clear from the text itself, the authors have used a quantitative approach to evaluate the data retrieved during the research. Quantitative research methods are believed to produce more credible and objective results, and it is especially important for those studies that are aimed at evaluating the outcomes of treatment. Unlike qualitative studies, quantitative ones do not usually pay attention to subjective data that can be falsified intentionally (such as the personal experience of participants) and it makes them a good choice for the field. The article discussed in the given paper aims at filling the knowledge gap that exists in the field and providing a systematic evaluation of the safety of medical cannabis. The research conducted by the group of authors presents all the necessary evidence; it has an ISRCTN registry which makes it more visible and credible. Introduction and Literature Review Speaking about the introduction section of the study, it is important to note that it is rather short if compared to other parts of the article as the researchers were paying more attention to presenting and explaining the results of the trial. At the very beginning of the section, the authors provide a rationale for conducting the study that seems to be adequate and comprehensive. To introduce the rationale, the authors present the information indicating that the use of medical marijuana for pain management and other purposes is still regarded as a controversial topic. According to the regulations accepted in Canada, patients who need to access medical cannabis for pain management and other medical purposes must present documents signed by healthcare professionals. At the same time, the authors highlight that there is a lack of substantial data on the effectiveness of medical cannabis and the safety of its use even though certain studies indicate positive outcomes for patients with chronic pain. To prove that the previous studies are not enough to make an informed conclusion on the effectiveness of cannabis for pain management, the authors mention that these trials were rather short and small samples were used. Considering that there are still health concerns related to the use of cannabis, the authors explain their decision by the lack of credible data on its safety evaluating its long-term effects. Therefore, the presented rationale is adequate. The significance of the study is obvious – using a large sample and presenting the results of a long-term experiment, the article fills the knowledge gap that exists in the field and provides additional evidence proving that the use of medical marijuana for pain management does not involve additional health risks for adult patients. The article can be supposed to make a difference to the field as it propels studying the safety of medical cannabis to the next level and helps to attract more attention to the lack of access to this method of treatment. According to the statements made by the researchers in the final section, the topic still needs to be studied because the given article reviews the outcomes for patients using medical cannabis for a yea