Introduction   * Organ transplantation is a very unique type of operation;   * Involves the transplantation of organs of living or deceased donors;   * Patients outnumber donors;   * Over 120,000 patients in the US alone need organ transplants (Pillay et al., 2014). Organ transplantation is an operation that involves transplanting a vital or essential organ from a living or a recently-deceased person to a patient in need. It is a very difficult operation that involves significant risks for both donors and patients, as there are chances of the body rejecting the organ. Because of the costs and extreme scarcity of organ transplants, the operation is suggested as a last resort only. The demand for organs outpaces the supply by a large margin, and there are 120,000 patients in the US alone waiting for an organ transplant (Pillay et al., 2014). The purpose of this presentation is to provide an overview of organ transplantation. Objectives of the Presentation   * What organs are typically replaced?   * Conditions that lead to organ transplantation.   * Signs and symptoms of organ failure.   * Treatments before and after transplantation.   * Nursing interventions. By the end of this presentations, the students would be provided with information about organ transplantation. The review will outline the organs that are commonly being transplanted, cite the various conditions that lead to organ transplantation as well as the common signs and symptoms of organ failure, and elaborate on how the patients are treated before and after the operation. Next, several nursing interventions aimed at improving success rates of the transplantation would be discussed. Organs Typically Replaced   * Heart – life-support organ;   * Intestine – essential organ;   * Kidney – essential organ;   * Liver – life-support organ;   * Lung – life-support organ;   * Pancreas – essential organ (UNOS, 2018). The main organs typically involved in transplantation can be divided into two groups (UNOS, 2018):   * Essential organs;   * Life support organs. The difference between them lies in the urgency of replacement. A person with a failing kidney can survive on one kidney alone for a period of time. A person experiencing a heart failure could die within 10 minutes after the cardiac arrest. Heart, lungs, and liver belong to life support organs, whereas the intestine, pancreas, and kidneys are considered essential organs for proper body functioning. Other organs may not be eligible to transplantation due to various complications associated with the operation. The brain, for obvious reasons, cannot be transplanted. Tissue transplantation, on the other hand, is much cheaper and safer, but does not offer a definitive solution. Conditions that Lead to Organ Transplantation   * Cardiomyopathy;   * Cirrhosis;   * COPD;   * Diabetes;   * Polycystic kidneys;   * Cystic fibrosis;   * Cancer (of all kinds) (UNOS, n.d.). The most common diseases that lead to organ transplantation are those that have the potential to damage and leave the organs unusable. These diseases include cardiomyopathy (affects the heart’s muscles and its ability to pump blood), cirrhosis (scarring of the liver due to various comorbidities), COPD (affects the airways and air sacks within lungs), diabetes (affects pancreas and organs that requ