This essay dealt on the role of culture in influencing healthcare choices of three distinct nationalities: Italian, American Indian, and Chinese. These nationalities have their own distinct medicine practices influenced by traditional beliefs. Professional nurses and healthcare providers have combined some of these practices with modern medicine. Practitioners and healthcare experts have recognised that there is a need to provide a study on traditional medicine and its role in modern medicine practices. Ann Hubbert (2008) of the University of Nevada argued that the healthcare profession must welcome and respect the existence of traditional practices, particularly the traditional Indian medicine (TIM), and recognize its role in healthcare and in the nursing practice. Chinese traditional medicine and nursing practices are recognised in western countries and many parts of Asia. Acupuncture and herbal medicine have been indorsed by the World Health Organization to cure minor illnesses like asthma and nausea. In Italy, family closeness influences their belief in the care of patients who are in persistent vegetative state (PVS) and end-of-life situations. Introduction This essay is about three different cultures: Italian, American Indian, and Chinese. We examined how these cultures influenced healthcare choices of the three nationalities and found their roles in the success of the treatment. The traditional Indian medicine (TIM) introduces healing as a way of living, as it relates with nature and the “forces” around us. The Chinese oriental and herbal medicine has been practiced for centuries. Italians have a few superstitions when it comes to treatment. But the three cultures have been woven through generations. The Italian culture, the TIM, and Chinese medicine are now influenced by modern medicine which, as they say, is an application of the scientific processes. There are some open-minded professionals who want to combine modern medicine with the traditional ways of healing. How this will be applied is up to the experts. For the main time, nurses should be open-minded about cultural sensitivities in the treatment processes of different cultures. Effects of Italian culture on health care choices Many Italians believe in superstitions, particularly about their concept of the “evil eye,” also known as “malocchio” In Italian. According to this belief, someone can inflict harm on somebody by having an evil eye on that person, and this eventually happens intentionally or unintentionally. The “evil eye” belief has some versions in other Latin countries, such Puerto Rico, and some Asian countries. If somebody in the family experiences a sudden illness (slight illness or discomfort), the belief is that someone has made an evil eye on that person. This usually occurs on children who cannot resist a bad spell. Some Italians consult faith healers before going to a physician. Another cultural practice is that before Italians seek professional help, they first ask the advice of a “therapeutic woman” who may perform some ritual to heal the illness. When a nurse encounters this kind of patient, the technique should be to “educate” first the patient. The first attempt of changing