Abstract When in pain or affected by a terminal illness, people often consider putting an end to their sufferings in any possible way. Euthanasia is one of the available methods in some cases, although this instrument is still highly debatable. For instance, even within the Christian perspective, which is associated with the idea of every life sacredness, two opposing views exist. On the one hand, euthanasia seems to be a sin and inappropriate method under any circumstances. On the other hand, some Christians admit that suffering and some health conditions can be a justification for euthanasia. The choice may depend on the angle to analyze the issue. For instance, those making end-of-life decisions may consider such aspects as fallenness of the world, the hope of resurrection, major Christian values, as well as people’s free will and cognition. George, who is diagnosed with amyotrophic sclerosis (ALS) and will have to face a rapid and dramatic deterioration of his health, is an illustration of the cases when euthanasia is justified. Introduction Palliative care is associated with one of the most challenging work environments as patients are exposed to pain and suffering due to their chronic conditions. At that, nursing professionals involved in other clinical settings may also need to consider issues related to end-of-life decisions. The Christian perspective has been long characterized by a strict and direct dogma regarding people’s life and death choices. However, Jones (2016) states that the debate regarding the matter has led to the appearance of two views even within the scope of the Christian tradition. In terms of the Christian worldview, such end-of-life decisions as euthanasia can be regarded as unacceptable, but they can still be possible under some circumstances, as seen by some Christians. However, the supporters of both views agree on one thing as they believe that every person (as opposed to a group of people (family) or society) is responsible for this kind of choice. The present paper includes an analysis of George’s case with a focus on the Christian worldview. Suffering and the Fallenness of the World George will have to go through a long period of suffering due to his health deterioration. Although he feels strong and healthy in his 50s, he will soon lose his ability to address his basic needs, including eating and even breathing. Amyotrophic sclerosis (ALS) is associated with physical pain, as well as mental and emotional suffering. From many perspectives, this situation may seem unfair and cruel, but it may make sense in terms of the Christian view. The fallenness of the world is one of the central ideas within the scope of the Christian picture of the world. With an emphasis on this aspect, George would see his suffering as a part of human existence that is made of pleasure, happiness, as well as pain and suffering. The Christian view of the world acknowledges its complexity, and such negative phenomena as suffering are regarded as another facet of human existence (Devettere, 2016). Therefore, people accept pain as an unfortunate given and try to focus on the pleasant or meaningful side of their being. The entire world is imperfect, and pain is one of these imperf