Psychoactive substance-related disorder ICD 10 Code F19.0 This disorder is characterized by a repeated pattern of indiscriminate drug usage that is illegal or beyond the intended prescribed limit. It results in compulsive behavior aimed to seek drugs and has detrimental effects on the brain. The disorder affects both social life and physical well-being: it induces a significant burden for patients by hindering the performance of their daily roles and activities while raising the occurrence of infections, suicidal and neuropsychological conditions (National Institute on Drug Abuse [NIDA], 2016). The factors defining the occurrence of drug use disorders include genetic predisposition and increased sensitivity of reward receptors in the brain, as well as the widespread availability of drugs, i.e., frequent prescription of opioid analgesics and a more open public attitude towards recreational narcotics (Miller, Oberbarnscheidt, & Gold, 2017). S & S: Exhibition of the indiscriminate and irregular taking of psychoactive substances with contributions of diverse types of drugs should be labeled as F.19 as disorders caused by multiple drug usage. Diagnostic classifications include acute intoxication (uncontrollable behavior), harmful use (evidence of physical or mental damages), dependence syndrome (the compulsion to obtain and use the substance), withdrawal state, and psychiatric disorder (American Psychiatric Association [APA], 2013). The use of cocaine presents symptoms of increased alertness, changes to behavior (including confusion or irritability), nausea (with potential weight loss), and damage to the nasal mucous membrane (Mayo Clinic, 2017). Pertinent positive data: The patient exhibits signs of a psychological dependence on drug use as a pain management tool and increased substance tolerance. Behavior changes include agitation and restlessness. Persistent nosebleeds confirm the deterioration of the nasal mucous membrane due to cocaine sniffing. Secondary Diagnosis Chronic pain syndrome ICD 10 Code G89.4 The condition is associated with consistent pain lasting for longer than 3-6 months after an expected healing time. It can affect any part of the body and lead to the development of various complications, stressors, and psychological factors adversely impacting a patient’s health. Chronic pain syndrome can be a behavioral condition that starts with a noxious stimulus provoking the reinforcement of pain behavior (Singh, 2017). It is common in elderly adults suffering from musculoskeletal disorders (Singh, 2017). S & S: enduring chronic pain (acute or persistent), discomfort, soreness interfering with daily activities, fatigue, and sleeplessness (Singh, 2017). Pertinent positive data: The patient shows issues with pain management over the years. The pain is chronic and is suspected to affect the nervous system. Differential Diagnosis Major depressive disorder, single episode, unspecified ICD 10 Code F32.9: The condition is associated with the emotion regulation deficit, which is considered the major predisposing factor for its development. Depression is characterized by an inability to influence the intensity and duration of the unfavorable emotional states. The given quality of the disorder leads to an inability to meet essential physio