Introduction Heart disease is a significant reason for disability and a leading cause for death in the United States by the statistics of the Centers for Disease Control and Prevention. Coronary heart disease is the commonest of the heart diseases (CHD) and often presents as a heart attack. About 785,000American were predicted to have a new coronary attack in 2009. About every 25 seconds, an American will have a coronary event and about every minute, an American will die from it. Many Americans suffer from a heart attack and they need to recover from it. Therefore, the purpose of this literature review is to identify the benefits of cardiac rehabilitation programs for CHD patients in terms of their psychosocial and physiological recovery. An advanced nurse practitioner (ANP) could recommend Cardiac Rehabilitation (CR) to CHD patients who go through a cardiac event in order to support their recuperation from the illness while providing the evidence why the CR is beneficial. Evidence-based nursing, based on the current best evidence available from researches, is the best quality of nursing care for the cardiac patient (Polit &Beck, Nursing Research, 2009). Healthcare professionals including nurses should acknowledge evidence of Cardiac Rehabilitation benefits and provide their patients with high quality of care. The American Heart Association (AHA) states that the core components of Cardiac Rehabilitation include baseline patient assessment, nutritional counseling, risk factor management (lipids, blood pressure, weight, diabetes mellitus, and smoking), psychosocial interventions, and physical activity counseling and exercise training. Review of the Literature Literature published between 2003 and 2009 was searched through multiple electronic databases; PubMed, CINAHL and Ovid. The search was conducted using keywords such as benefits of cardiac rehabilitation, Coronary Heart Disease, quality of life, risk factors modification and depression. The searches revealed some interesting facts. Kardis et al (2005) conducted a study to compare quality of life assessments after a 3-month Phase II cardiac rehabilitation program following a cardiac intervention. Fast et al (2009) studied the effects of attending Phase II cardiac rehabilitation on patient versus spouse (proxy) quality-of-life perceptions. Both of them investigated the benefits of cardiac rehabilitation on quality of life, but Fast et al (2009) compared the perception of quality of life between patients and their spouse in addition. While Snow et al (2005) conducted the research of effects of cardiac rehabilitation on lipids in Coronary Artery Disease (CAD), Adams et al. (2007) focused on a comparison study of cardiovascular risk factor outcome including lipid levels between exercise-based cardiac rehabilitation, traditional care, and an educational workshop among CAD patients. Milani et al (2007) highlighted depression and its associated mortality among coronary artery patients and used cardiac rehabilitation programs as an intervention. In all five research articles, the authors described their CR and the programs have the same core components of CR since the programs follow the AHA recommendations. Research Design Kardis et al (2005) used one group pretest-posttest design which is a weaker quasi-experimental or pre-experimental des