The pomegranate, the scientific name ‘Punica granatum L.,’ is a fruit-bearing deciduous shrub that contains thousands of health benefits, as stated three times in the Holy Qur’an. The plant’s many applications prove its advantages as fruits that are beneficial to human beings. The term ‘pomegranate’ is the English name, while ‘al-Rumman’ or ‘al-Rummanah’ is Arabic (Munirah, 2011). In ancient times, the Old Testament of the Bible, the Jewish Torah, and the Babylonian Talmud describe the pomegranate as a divine fruit conferring forces of fertility, good luck, and abundance. Punica granatum L. has a long history of use as a traditional or herbal medicine source. 1 , 2 The fruit of the pomegranate has medicinal properties, including anti-inflammatory and antibacterial ones. For instance, skin and breast cancers are both inhibited by pomegranate seed oil due to its anti-inflammatory action. Punica granatum L. fruit is high in phenolic compounds with significant antioxidant activity, and the seed oil contains phytoestrogenic compounds. Pomegranate fruit and bark are used to treat intestinal parasites, dysentery, and diarrhea. 1 The juice and seeds are used as a throat and heart tonic. The concoction of seeds and juice is also employed to treat hemorrhoids and avoid nose and gum bleeds. 3 Punica granatum L. is now a fruit that not only entices the public’s attention but also draws research into its therapeutic properties and food industry. 3 As a result of pomegranate’s possible medicinal and industrial use, plenty of research studies in this area have already been initiated. However, there has not been enough research on pomegranate’s antioxidant function. Pomegranate ( Punica granatum L.) is one of the earliest domesticated fruits known to people. It spreads from Central Asia to the Himalayas, Anatolia’s Eyalet, the Middle East, and the Mediterranean. Pomegranates are also grown in Arizona, California, and the Mediterranean. South Asia and Middle Eastern countries, including Kandahar and Afghanistan, are known for their high-quality pomegranates. Pomegranates are now grown in Saudi Arabia, Spain, Italy, Afghanistan, America, India, China, Russia, Uzbekistan, Morocco, and Greece, among other places. Sugars, organic acids, polyphenols, flavonoids, anthocyanins, fatty acids, alkaloids, vitamins, and other metabolites are contained in different parts of the Punica granatum L. fruit and tree. The essential sugars found in the Punica granatum L. extract are glucose, fructose, sucrose, and maltose, while the vitamins are C, B1, B2, and beta-carotene. Malic acid, fumaric acid, oxalic acid, succinic acid, citric acid, and tartaric acid are only a few of the primary organic acids contained in Punica granatum L. Alkaloids present in pomegranate peel include ellagic acid, gallic acid, chlorogenic acid, cinnamic acid, protocatechuic hydroxy acid, hydroxybenzoic acid, caffeic acid, ferulic acid, coumaric acid, p -coumaric acid, and o -coumaric acid. The pomegranate’s bark can also yield pelletierine, isopelletierine, methylpelletierine, pseudopelletierine, punicalagin, punicalin, phloridzin, quercetin, and catechin. 6 , 7 Luteolin, kaempferol, and narigenin are flavonoids present in glycoside forms in Punica granatum L. 7 , 8 Anthocyanin is the main compound in pomegranate that is responsible for color induction. Anthocyanin is a glycosid