Introduction Workflow, loosely considered, is a series of assignments chronologically clustered into various processes and personnel and other resources required for those roles identified, which are vital to accomplish specific objectives. In hospitals, for instance, a workflow normally reflects various processes needed to realize care delivery goals. In this case, healthcare providers and other resources must be present to perform these processes and facilitate interactions for desired outcomes. The primary role of workflow analysis in healthcare settings is to enhance efficiency. The purpose of this research paper is to assess workflow analysis for advance directives. It presents a workflow issues analysis, diagram, method of analysis, evidence-based recommendations and conclusion. Workflow Issues Analysis Health information technology, if executed well, can enhance efficiency and organizational workflow. Documented advance directives (ADs) can significantly curtail notable discrepancies between care delivery preferred and the actual care delivered to a patient. It is estimated that about 43% of senior citizens in the US would require critical healthcare decision related to near the end-of-life (Gabler et al., 2016). However, about 70% of these patients cannot take part in decision-making processes and, therefore, rely on others to make decisions for them (Gabler et al., 2016).ADs, which generally consist of the patient’s living will and the power of attorney designation – useful for enhancing the quality of advance care planning for patients. Studies have suggested that both academic medical setting and inpatient setting are not ideal for discussing end-of-life issues with patients (Allen et al., 2015; Gabler et al., 2016). On this note, outpatient setting offers an ideal opportunity for ADs but with some limitations (Gabler et al., 2016). In outpatient settings, poor outcomes are noted in about 5% to 30% cases based on the definition adopted, the population, and the clinical setting. Specifically, physicians have reported challenges associated with inadequate time, poor accessibility of AD in the medical record, and a lack of prior discussion about the end-of-life care with the patient and family (Hayek et al., 2014). In addition, it is also observed that in healthcare settings, there are instances of creating and collecting redundant information about patients. Consequently, nurses, physicians, and other care providers spend much time in attempts to reconcile information obtained from disparate sources. Health IT solutions offer workflow integration opportunities across different departments to curtail redundancy. Nevertheless, if workflow processes are not accounted for and IT platform is not carefully executed, then no hospitals can truly realized the intended outcomes. Effective use of IT in healthcare settings can only be realized through transformed care delivery. In addition, interactions that are more complex have also been noted among healthcare providers, which could hinder documentation. It is noteworthy that the introduction of health information technology driven by informatics and the mass adoption of electronic health medical records (EMRs) have introduced innovative approaches for streamlining care delivery, docum