Introduction Asthma is one of the immunological illnesses. Asthma and allergic disease belong to the same category of inflammatory illnesses, caused by abnormal responses of the immune system in the respiratory system. Asthma and allergic illnesses make up some of the current health issues across the world as many people are suffering from the illnesses. Scientists are yet to create a clear understanding of the chemicals responsible for triggering asthma and allergic disease (Johnson, 2013). T-helper-2 initiates immunological responses in the respiratory system, and they lead to the development of asthma. T-helper-2 originates from the CD4+ cells, and it is responsible for stimulating the production of mucus in the respiratory system. The T-helper-2 causes excessive production of mucus in the respiratory system, and it also causes the muscles in the system to become hyperactive. This leads to the development of asthma, which involves the inability of the victim to breathe normally. The air passages in the respiratory system fill up with mucus, and the hyperactivity of the muscles makes it difficult for the victim to control breathing. Victims have access to limited air in their lungs. Researchers have identified that immune responses caused by the T-helper-2 have a link with both asthma and allergic reactions. The production of the Th2 initiates when the victim gets in contact with allergens, contaminated air, and other infections (Umetsu & DeKruyff, 2006). T-helper-2 and asthma Asthma is characterized by abnormal inflammation in the respiratory cells because of the T-helper-2 response in the cells. Non-asthmatic people can inhibit TH2 response; hence, their respiratory system is not affected by allergens and other infections that may lead to asthma attacks. When asthmatic people get into contact with some particles in the air they breathe, their CD4+ cells respond by releasing Th2 cells, which cause inflammation in the cells within the respiratory system. In the normal immunological responses, regulatory T-cells are released to counter the effects of the Th2 cells; thus, preventing inflammation. Cytokine IL-10 plays a big role in causing an anti-inflammatory effect on the cells. The immunological response in asthmatic people fails in the regulation of the production of the Th2 cells and the anti-inflammatory cells (Johnson, 2013). The breakdown in immunological response happens every time asthmatic people come into contact with infections and allergens because their system is configured to respond without the production of the anti-inflammatory cells. Treating asthma involves administering medications that trigger the attainment of a balance between the production of the Th2 and cytokine cells (Lloyd & Hawrylowicz, 2009). Studies Various researchers from different institutions across Southampton undertook a joint study to identify the roles of different T- cells in the immune system. The researchers were particularly interested in finding out the role played by Th17, Th2, and Th1 among several other cells. The researchers used a sample space of 84 participants. The participants went through various experiments aimed at detecting the release of T-cells, and the effects they had on other cells. The findings revealed that Th2 plays a big role in causing inflammatory effects in the respiratory system of asthmatic people.