Introduction Nowadays, every large-scale disaster generates an international humanitarian response. Many groups, such as the Red Cross, the UN-backed agencies, the international non-governmental organizations, and various state institutions are quick to respond to these threats by sending supplies, medicaments, resources and volunteers to the afflicted areas around the globe (Gilman & Noyes, 2013). Despite the actions being noble, altruistic, and humanitarian in nature, many systematic networks such as ALNAP report the staggering inefficiency of most of these initiatives, which leads to wasted resources, lower recovery rates, and as a result, more lives lost (Clark & Darcy, 2014). One of the major reasons for these humanitarian failures is the lack of proper evidence generation and implementation mechanisms. The recent cascade failures of the current humanitarian system are demonstrated by its inability to prevent chain-famines in the Sub-Saharan areas of Africa, despite the early warning systems being in place (Broadbent, 2012). This highlights the problem that the organizations are not only unable to properly generate evidence, but use it as well, even if quality evidence is ample and available. The evidence is crucial to humanitarian action, just as much as proper logistics and funding. Without it, the humanitarian effort is often ineffective, unethical and unaccountable. All three are paramount to the success of the intervention. How does evidence affect these three criteria, upon which it will be judged? Evidence, or lack of it, directly influences the effectiveness of a humanitarian effort, as without information the participating organizations cannot devise a coherent and adequate strategy, which would address the critical aspects of a situation (Ashdown, 2011). An action based on insufficient evidence cannot be considered ethical. One of the core principles of humanitarian actions is impartiality. Impartiality suggests analysing the entire spectre of available choices and picking the best one, avoiding as much bias as it is humanly possible. Without evidence, this goal becomes unachievable, as the entirety of available choices is not available to the decision-maker. In addition, actions based on insufficient evidence are ineffective at best, or harmful at worst (Dijkzeu, 2013). The last issue is accountability. This has a lot to do with finances, fund-raisings and money spending. The majority of humanitarian organizations are funded by independent donors, governments, societies, or exist on taxpayer money. This makes the organizations accountable to a great number of people. They have to provide reasons why, how, and how effectively the money is spent. Without evidence, it becomes hard to justify these expenses or prove that the interventions were indeed effective (Tan & Schreeb, 2015). In order to improve the situation, a shift towards evidence-based practices is required. Evidence-based practices are widely implemented in medicine and nursing. In the past 20 years, evidence-based medicine made huge leaps in both quality and effectiveness of its applications (Stevens, 2013). It is strange that while the modern medical effort is thoroughly evidence-based, the