Summary of the Topic The article by Roth (2012) addresses the issue of gene-environment and the important role it plays in determining the functions of the brain. According to Roth (2012), the changes taking place during the early stages of development in a human being, especially those taking place in sensitive areas, may result in alterations in the genes. However, the changes do not necessarily affect the structure of the DNA. According to Roth (2012), some of the behaviors found in children result from DNA methylation and histone acetylation. The two are biomechanical processes known as epigenetics. The behaviors referred to here are especially those emanating from stress, parental care, and abuse. In the article, Roth (2012) also analyzes neurobiological changes. To this end, epigenetic mechanisms are believed to affect developmental changes in neurobiology and behavior. Human memory stores a lot of information from the past. According to the article by Roth (2012), the individual can learn from some of these recollections. Different experiences, such as those to do with prenatal stress and infant separation, may interfere with the formation of associative fear memory. The interference affects the ‘filing’ of some of the experiences in the memory. As such, the individual may get affected any time they recall those experiences stored in the brain (Roth, 2012). According to Roth (2012), epigenetics explain how adulthood stressors can change the functions of the brain. Change in the behavior of the brain may lead to psychiatric disorders. The reason is that the alterations are brought about by dysregulation of epigenetic mechanisms in the body. Introduction to Child Sex Abuse and its Impacts on Adult Psychopathology As a social problem, child molestation is brought about by a number of factors. In some cases, analysts have shown that parents play a direct or indirect role in the sexual harassment of their children. Loss of self-esteem and trust are some of the impacts that go beyond childhood. Others are a sense of guilt and mixed feelings (Breedlove & Watson, 2013). A number of biological changes are likely to occur in the brain of the minor. Such developments change their behavior depending on the intensity of the situation (Beach et al., 2013). Child sex abuse may also lead to epigenetic changes in the DNA of the individual. However, it is noted that the changes do not affect the structure of the DNA (Ducci et al., 2008). On the contrary, they only alter how it expresses itself in the body. Reduction in gene expression is induced by DNA methylation. The condition leads to the development of a disease in the area of DNA (Roth, 2012). If the methylation happens to occur in the brain, then the individual is likely to have problems relating with other people (McGowan et al., 2009). The DNA methylation process is used to explain how the brain can be affected by incidences of molestation at childhood. Consequently, Beach et al. (2013) used a model to test parents and children from families associated with symptoms of antisocial personality disorder. Methods and Results Methods Beach et al. (2013) used adoptees and adoptive parents recruited from Iowa region.