There are myriads of infections prevalent in healthcare settings. As a matter of fact, the rising rates of both mortality and morbidity have been attributed to the spread of contaminations in hospital facilities. About 1.7 million new infections are associated with contaminated hospital settings every year. For instance, patients’ endogenous Flora is believed to be the main cause of the nosocomial pathogens that have increased mortality rates in hospitals (Rutala, Gergen & Weber, 2013). Besides, infected hands of hospital personnel are known to be major sources of pathogens. The magnitude of cross infection from hospital personnel is quite high. It is against this backdrop that proper and effective decontamination measures should be put in place in all hospital facilities in order to minimize both morbidity and mortality rates. There are myriads of methods that can be used to clean patents’ rooms in hospital settings. For instance, chemical germicides have been used for long in decontaminating both ground and wall surfaces. As much as such rooms can be cleaned about four times per week in order to reduce infection levels, chemical germicides may not be able to eliminate all forms of pathogens present in hospital settings. Moreover, a lot of work is required when using chemical germicides to disinfect hospital settings. This explains why most well established healthcare facilities are gradually transiting to the use of Ultra-Violet (UV) rays to decontaminate hospital portions frequented by patients. Room cleaning can only be improved when UV light is used especially when it comes to the elimination of hidden pathogens. Pathogenic microorganisms can be effectively controlled using the UV radiation when compared to chemical disinfectants. In addition, the radiation can be applied in a number of ways. For example, hospital instruments, hidden surfaces, and air can be disinfected using UV light (Boyce, Havill & Moore, 2011). Control of legionellosis has also been made possible through UV radiation. The molecular bonds of the DNA sample are easily broken down in the presence of UV light. This cannot be achieved using ordinary cleaning agents. When such bonds are broken, the pathogenic organism is rapidly destroyed. A mobile UV-C unit that has been automated can eliminate thousands of varieties of bacteria. Both the C . difficile and Acinetobacter baumannii bacteria that usually hide below open surfaces can be destroyed using the UV radiation. It is also interesting to mention that aerobic bacteria have been successfully eradicated using UV radiation. In any case, the germically-active portion of most pathogens coincides with the strongest wavelength of the UV radiation. The graph below shows the impact of using the ARTZ machine for decontaminating a hospital setting. From the illustration, it is evident that the percentage of the C . difficile bacteria went down considerably within a period of three years. A number of parameters work positively towards enhancing the effectiveness of UV radiation. Examples of these parameters include patterns of air movement, lamp placement, exposure time and intensity of the radiation. As already hinted out, several healthcare-associated pathogens can be effectively controlled using the UV rays. In other words, the radiation is