Summary The research is aimed at investigating the general effects of the accelerated use of pharmaceutical and other personal care products by humans on aquatic ecosystems. These pharmaceutical wastes constitute most of the domestic wastes which make up more than half of the total waste disposed of by the municipal (William, 2005). The study also focuses on identifying the existing ways of treating the effluents. Once discharged in the aquatic environments, the levels at which this toxic can be adverse are examined and regulated. The study specifically looks into the effects of sertraline hydrochloride commonly referred to as Zoloft. Zoloft is regarded as an antidepressant used to treat depression, as well as anxiety disorders. It aims at investigating the possible effects of Zoloft and the possible concentrations at which exposure can cause adverse effects. In addition, it also aims at identifying the endpoint effects of exposure to the organisms and the aquatic ecosystem as a whole. A major issue addressed in the study is the force drivers that are responsible for the increased usage of these products. The paper includes economics, as well as social forces, steering the over-reliance on the products also discusses in depth the implication of not addressing the issue at an earlier stage. Zoloft has proven to be capable of causing adverse effects even at low-concentration levels also the lack of conventional methods of waste treatment, as highlighted in the study, also proves that the increased usage of these pharmaceuticals is a disaster in the making. According to William, Zoloft’s presence in the aquatic ecosystems can cause various effects in the present organisms for instance the fish are affected by the constituent chemicals of these antidepressants as well as psychological or behavioral effects to other organisms (William, 2005). In summary, the research also addresses the issue of a wide market for pharmaceuticals arising from the increased prescription of the antidepressant especially in Canada and the United States. This prescription comes hand in hand with increased waste disposal in the waters consisting mainly of Zoloft. A lot of people suffering from major depressions and anxiety have been prescribed Zoloft. this is because, according to research, their side effects are a little less pronounced and are also efficient than other prescriptions. It is also discussed in-depth, the reason why most of the patients prefer this kind of treatment to others, which could be a bit environmentally friendly (Kummerer’s, 2010). Highlighted in the study is the problem evidenced by the lack of solutions implemented to combat the effects of these Zoloft on the organisms in the aquatic environment. In the current generation, basing arguments on kummerer’s green and sustainable pharmacy, there are less effective modes of treatment of pharmaceutical discharge in the water. The study addresses the issue of solution-finding as well as recommendations for the future generation on dealing with these discharges. Dire future recommendations expounded in the research paper include ways of ensuring the wastes do not find their way into the water. This can be considered as a method of eliminating the carrier agents or the causative agents that end up discharging the waste