Introduction It should be noted that the previous studies of the homeless population were partially based on the data from quantitative research. However, qualitative research also appears to be a very beneficial tool for the investigation of the topic. In particular, this paper aims to observe the application of qualitative research to the chosen vulnerable population group and to utilize the life history methodology according to the developed outline of the research proposal. Additionally, two related scientific approaches will be discussed, and also the question of determining gaps in the literature about the topic will be mentioned. Designing a Qualitative Research Application of Ethical Principles It could be hardly denied that the issue of homelessness is in many ways connected with ethical dilemmas and questions. When conducting qualitative research, it is critical to be consistent with one of the most important moral principles of respecting autonomy since every individual has a free will to decide how he or she lives his or her life. Also, the principle of beneficence is also of high importance because the primary goal of any vulnerable population research is to improve people’s quality of life. How Qualitative Research Study Is Designed The critical difference between quantitative and qualitative research is that the latter is primarily based on the exploration of ideas and underlying reasons rather than on the gathering of precise, numeric data. Qualitative research provides the understanding of the current situation or upcoming trends by the investigation of people’s ideas and experiences and the provision of helpful insights into different aspects of the research question. In the majority of cases, this type of study provides a basis for further quantitative research. Developing an Outline for a Research Proposal It is possible to note that one of the more frequently employed types of qualitative research is the interview. For this study, it was decided to utilize the life history methodology since it could be “an important, relevant and appropriate contribution” to the studying of the homeless vulnerable population (Etherington, 2009, p. 225). It is also possible to notice that the mentioned approach is vastly based on the concept of discourse, developed by Michel Foucault, according to which “narratives are seen as ways of positioning oneself as a subject” (Germeten, 2013, p. 612). Developing an outline for the interview with a member of a homeless vulnerable population group, it is possible to set the following objectives:  1. to ask about positive and negative role models  2. to impose broad questions about barriers to success and facilitative factors  3. to encourage an individual to recount his or her personal story and its critical points. Report of the Interview The interview was conducted with a member of the homeless vulnerable population group, who is male, White, 28-year-old. The major concepts that emerged in this interview were:  1. vulnerability as an integral part of life  2. experiencing the ethical dilemmas from the personal perspective  3. the quality of life as a complex factor. These concepts were synthesized from the interview, in which the participant was describing his everyday life. From the researcher’s perspective