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+++ "b/test.jsonl"
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+{"text":"The use of somatostatin analog in gastroenteropancreatic tumors other than carcinoid.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was given methimazole instead of propylthiouracil but, 10 weeks later, agranulocytosis again occurred.","label":1,"label_text":"Related"}
+{"text":"Ethambutol is an antimicrobial agent used frequently to treat tuberculosis.","label":0,"label_text":"Not-Related"}
+{"text":"Dofetilide has been shown to be effective and safe in maintaining sinus rhythm in patients with persistent atrial fibrillation and congestive heart failure.","label":0,"label_text":"Not-Related"}
+{"text":"IgG1 and IgG4 were the predominant IgG subclasses in the glomerular deposits.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment with octreotide brought about the remission of diarrhea in this patient.","label":0,"label_text":"Not-Related"}
+{"text":"It was characterized by hyperandrogenism and polycystic ovaries in all cases, and it was associated with weight gain and menstrual disorders in 2 of the 3 women.","label":0,"label_text":"Not-Related"}
+{"text":"Noncirrhotic portal hypertension: another cause of liver disease in HIV patients.","label":0,"label_text":"Not-Related"}
+{"text":"Since this amount of FAB was insufficient to bind all DGTX present in the serum, cardiac DGTX toxicity (total AV-block) persisted.","label":1,"label_text":"Related"}
+{"text":"These results indicate that the hyponatremia in this case was due to SIADH and that SIADH was caused by an increased release of vasopressin probably because of the antiviral drug (acyclovir) or infection of varicella zoster virus (VZV) in a single dermatome.","label":0,"label_text":"Not-Related"}
+{"text":"CONTEXT: Radiation recall has been described in the context of gemcitabine chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Antiarrhythmic agents can cause pneumonitis.","label":0,"label_text":"Not-Related"}
+{"text":"Flavimonas oryzihabitans has been isolated from a wide range of body sites, and the portals of entry are major wounds or implanted foreign materials.","label":0,"label_text":"Not-Related"}
+{"text":"Severe hyperkalemia as a complication of timolol, a topically applied beta-adrenergic antagonist.","label":1,"label_text":"Related"}
+{"text":"Since 1955, a number of phenothiazines had been tried, also with little improvement.","label":0,"label_text":"Not-Related"}
+{"text":"In humans, 80-90% of an administered dose of 5-fluorouracil (5-FU) is degraded by dihydropyrimidine dehydrogenase (DPD; EC 1.3.1.2), the initial rate-limiting enzyme in pyrimidine catabolism.","label":0,"label_text":"Not-Related"}
+{"text":"Diagnosis of TTS is one of exclusion as it can mimic many other conditions, and should be considered in patients with unilateral painless ulcerations with a history of trigeminal nerve damage.","label":0,"label_text":"Not-Related"}
+{"text":"High-resolution computed tomography scan findings were consistent with ILD, which was sufficient to diagnose as erlotinib-induced ILD.","label":1,"label_text":"Related"}
+{"text":"Following the institution of intravenous therapy with acyclovir, the patient developed fever, hemoptysis, and a pleural friction rub.","label":1,"label_text":"Related"}
+{"text":"NEH occurs most frequently in patients receiving chemotherapy for haematologic malignancies.","label":0,"label_text":"Not-Related"}
+{"text":"This case illustrates an association between CMV and TMA in a transplant patient with resolution of the latter after treatment of the CMV.","label":0,"label_text":"Not-Related"}
+{"text":"Olanzapine is a relatively new antipsychotic drug used in the United States for the treatment of schizophrenia.","label":0,"label_text":"Not-Related"}
+{"text":"Intrahepatic cholestasis and cutaneous bullae associated with glibenclamide therapy are described in a 61-year-old diabetic patient who presented wit hypoglycaemic coma.","label":1,"label_text":"Related"}
+{"text":"BK virus-associated nephropathy (BKVN) has become recognized as an important cause of allograft dysfunction in renal transplant recipients and despite reduction in immunosuppression, 30-40% of recipients ultimately progress to allograft loss.","label":0,"label_text":"Not-Related"}
+{"text":"The mechanisms by which these agents interact to produce prolonged hypoglycemia are complex and probably multifactorial.","label":0,"label_text":"Not-Related"}
+{"text":"Local ILP toxicity appeared with extensive edema and common peroneal neurologic impairment including paresis that remained severe 10 months later.","label":0,"label_text":"Not-Related"}
+{"text":"The patient sustained a severe septic episode, was treated with antibiotics and GM-CSF, and recovered the 14(th) day after ticlopidine withdrawal.","label":0,"label_text":"Not-Related"}
+{"text":"He developed optic atrophy and steroid complications, including cushingnoid features and growth maturation delay.","label":0,"label_text":"Not-Related"}
+{"text":"In all 5 patients the need for oral corticosteroid therapy was substantially decreased or eliminated, thus decreasing potential corticosteroid-induced morbidity.","label":0,"label_text":"Not-Related"}
+{"text":"Ganciclovir and standard high-dose immunoglobulins were administered to the patient with resolution of the pneumonia.","label":0,"label_text":"Not-Related"}
+{"text":"This article describes a patient with suspected ciprofloxacin-induced interstitial nephritis.","label":1,"label_text":"Related"}
+{"text":"The prevalence of pregnancy loss in women with FMF is considered to be high.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was well on routine follow-up at the outpatient clinic, with no progression of lymphoma or interstitial pneumonitis.","label":0,"label_text":"Not-Related"}
+{"text":"A patient with psoriasis is described who had an abnormal response to the glucose tolerance test without other evidence of diabetes and then developed postprandial hyperglycemia and glycosuria during a period of topical administration of a corticosteroid cream, halcinonide cream 0.1%, under occlusion.","label":1,"label_text":"Related"}
+{"text":"Olanzapine is a newly developed atypical neuroleptic with a marked affinity to the 5-HT2, D2 and D4 dopamine receptors.","label":0,"label_text":"Not-Related"}
+{"text":"An association between gadolinium-containing contrast and the development of nephrogenic systemic fibrosis (NSF) has been increasingly recognized.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment for up to 2 years with SMS controlled symptoms, suppressed serum gastrin, and suppressed acid secretion.","label":0,"label_text":"Not-Related"}
+{"text":"A repeat sodium was 124 mmol\/L, and she was admitted.","label":0,"label_text":"Not-Related"}
+{"text":"Other clinical symptoms of sarcoidosis resemble side-effects of interferon.","label":0,"label_text":"Not-Related"}
+{"text":"De novo absence status of late onset following withdrawal of lorazepam: a case report.","label":1,"label_text":"Related"}
+{"text":"Lupus-like syndrome caused by 5-aminosalicylic acid in patients with inflammatory bowel disease.","label":1,"label_text":"Related"}
+{"text":"The aim of this study is to assess the impact of oseltamivir on the control of INFVA infection in BMT recipients.","label":0,"label_text":"Not-Related"}
+{"text":"The optimal length of therapy is not known, though there are indications that treatment can be discontinued shortly after seizure control.","label":0,"label_text":"Not-Related"}
+{"text":"Thrombolysis with recombinant tissue plasminogen activator is the only established treatment for acute ischemic stroke.","label":0,"label_text":"Not-Related"}
+{"text":"Anaphylactic\/anaphylactoid reactions to methotrexate are rare.","label":0,"label_text":"Not-Related"}
+{"text":"Changes in serotonergic function may play a more widespread role in the pathophysiology of seizure disorders than hitherto thought.","label":0,"label_text":"Not-Related"}
+{"text":"Alzheimer type II glias and abnormal glias closely resembling Alzheimer type I glia were numerous in the affected white matter.","label":0,"label_text":"Not-Related"}
+{"text":"Cutaneous adverse reactions to 8-methoxypsoralen (8-MOP) appear to be rare and may be difficult to distinguish from phototoxicity or UV-induced polymorphic light eruption.","label":0,"label_text":"Not-Related"}
+{"text":"Patients were treated with CPA at the doses of 200-300 mg\/d for malignant prostate disease for 3-12 mo prior to the acute manifestation of the hepatic disease.","label":0,"label_text":"Not-Related"}
+{"text":"Introduction of the balloon into the left atrium resulted in thrombotic occlusion of the mitral valve.","label":0,"label_text":"Not-Related"}
+{"text":"Severe erythroderma as a complication of continuous epoprostenol therapy.","label":1,"label_text":"Related"}
+{"text":"A within-series phase change design (ABABC) was used to evaluate the effect of video distraction and relaxation in the treatment of a 29-year-old male with anticipatory vomiting associated with cancer chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Six patients were identified.","label":0,"label_text":"Not-Related"}
+{"text":"The relationship between BP and chronic renal failure and\/or hemodialysis is not clear, but we believe that immune disarrangement due to chronic renal failure and\/or hemodialysis may have influenced the pathogenesis of BP in our case.","label":0,"label_text":"Not-Related"}
+{"text":"MAIN RESULTS: Followup echocardiogram on day 10 showed complete resolution of the thrombus.","label":0,"label_text":"Not-Related"}
+{"text":"Dapsone-induced erythroderma with Beau's lines.","label":1,"label_text":"Related"}
+{"text":"Neutropenia-wise and pound-foolish: safe and effective chemotherapy in massively obese patients.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Neurologists have a vast armamentarium to treat both motor and nonmotor manifestations of PD.","label":0,"label_text":"Not-Related"}
+{"text":"More than 50 cases of tuberculous peritonitis complicating CAPD that have been reported in the English-language literature since the initial case was reported in 1980 are reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"In rare cases, EM presents continuous or persistent relapses, and has been related to an Epstein-Barr virus infection.","label":0,"label_text":"Not-Related"}
+{"text":"One of these was clofazimine, an aniline aposafranine derivative known to produce a ceroid-like pigment in the tissues of patients treated with this drug or lepromatous leprosy.","label":1,"label_text":"Related"}
+{"text":"Intrasellar and parasellar tumors made manifest by hormonal influences of pregnancy may become more common as treatment of infertility becomes more refined and successful.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of a patient with increased cerebral cortical excitability following intoxication with flupirtine, a centrally acting analgesic and antispastic drug.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: Severe neuroleptic sensitivity and associated deficits of cognitive speed occurred in response to a dopaminergic antagonist agent; both responded readily to withdrawal of the offending agent.","label":0,"label_text":"Not-Related"}
+{"text":"A case of timolol-associated heart failure in a 73-year old white man is reported.","label":1,"label_text":"Related"}
+{"text":"A 57-year-old male developed an adenocarcinoma lung cancer in November 2003.","label":0,"label_text":"Not-Related"}
+{"text":"The patient developed a broad-QRS-tachycardia and severe hypotension.","label":0,"label_text":"Not-Related"}
+{"text":"We report 3 patients who developed cutaneous vasculitis which is a rare and serious side-effect during antithyroid drug therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Desensitization with methotrexate was successful and allowed the patient to complete 12 additional courses of chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"In the second case, five cardiac arrests due to ventricular tachycardia and fibrillation occurred during several hours after beginning a trial of bretylium maintenance therapy for complex ventricular ectopy.","label":1,"label_text":"Related"}
+{"text":"Long-term use of topical tacrolimus (FK506) in high-risk penetrating keratoplasty.","label":0,"label_text":"Not-Related"}
+{"text":"Azithromycin is considered unlikely to interact with warfarin.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients treated with 5-fluorouracil (5-FU) for disseminated adenocarcinoma of the colon developed cerebellar dysfunction typical of 5-FU neurotoxicity.","label":1,"label_text":"Related"}
+{"text":"A 25-year-old man with a history of mid-borderline (BB) Hansen's disease developing a reversal reaction after starting dapsone and rifampin therapy is presented.","label":1,"label_text":"Related"}
+{"text":"This progressed to tracheal compression with stridor after he had taken some aspirin for relief of the neck pain.","label":1,"label_text":"Related"}
+{"text":"In this report and other reports describing successful resuscitation, the total dose of sodium bicarbonate is conspicuously higher than in reports describing extracorporeal interventions.","label":0,"label_text":"Not-Related"}
+{"text":"Reduction of tumor burden and stabilization of disease by systemic therapy with anti-CD20 antibody (rituximab) in patients with primary cutaneous B-cell lymphoma.","label":0,"label_text":"Not-Related"}
+{"text":"Erythroid engraftment was successful with primary steroid treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Macrolide antibiotics cause ototoxicity, which occurs most frequently when high serum concentrations are achieved.","label":0,"label_text":"Not-Related"}
+{"text":"He developed Epstein-Barr virus-associated malignant lymphoma at 10 years and thyroid papillary carcinoma at 20 years of age.","label":0,"label_text":"Not-Related"}
+{"text":"Amyloid goiter in a child with familial Mediterranean fever.","label":0,"label_text":"Not-Related"}
+{"text":"Rhabdomyolysis caused by Commiphora mukul, a natural lipid-lowering agent.","label":0,"label_text":"Not-Related"}
+{"text":"The authors present two patients in whom it was necessary to substitute the Erwinia enzyme for the E. coli enzyme because of the occurrence of severe allergic reactions to the E. coli enzyme.","label":0,"label_text":"Not-Related"}
+{"text":"Infections seem uncommon.","label":0,"label_text":"Not-Related"}
+{"text":"One and a half hours after receiving 110 mg suxamethonium for oesophagoscopy, the patient was still apnoeic with no response to ulnar nerve stimulation.","label":0,"label_text":"Not-Related"}
+{"text":"Children receiving zonisamide should be monitored for oligohidrosis and the development of neurological symptoms associated with an elevation of body temperature.","label":1,"label_text":"Related"}
+{"text":"In addition, cultures of specimens obtained at autopsy did not reveal a cause for the heart failure.","label":0,"label_text":"Not-Related"}
+{"text":"Ocular symptoms began between 3 and 6 months after transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of a patient with severe digitoxin intoxication by Fab fragments of anti-digitalis antibodies.","label":0,"label_text":"Not-Related"}
+{"text":"He was transferred to our hospital when he was discovered to have acute renal failure with hyponatremia (118 mEq\/L) and severe rhabdomyolysis (creatine phosphokinase, 227,200 IU\/L).","label":0,"label_text":"Not-Related"}
+{"text":"We aimed to report a case with rhabdomyolysis related to hyponatremia and\/or its correction.","label":0,"label_text":"Not-Related"}
+{"text":"DISCUSSION: Rhabdomyolysis is a clinical syndrome resulting from the destruction of skeletal muscle that may progress to renal failure Several drugs have been associated with rhabdomyolysis, including lovastatin, a hydroxymethylglutaryl-coenzyme A reductase inhibitor.","label":1,"label_text":"Related"}
+{"text":"This case highlights the potential of ritonavir interactions even with local injections of a corticosteroid.","label":0,"label_text":"Not-Related"}
+{"text":"Hence, hyperthyroidism induced by IFN-alpha could correspond to the first phase of silent thyroiditis, to Graves' disease or to the succession of both.","label":1,"label_text":"Related"}
+{"text":"A 65-year-old man on warfarin therapy with a sudden spontaneous onset of sub-conjunctival haematoma associated with bloody tears was assessed in the clinic following a referral from an optometrist.","label":1,"label_text":"Related"}
+{"text":"However, she was unable to follow commands and she expressed rigidity of extremities, mild tachycardia, and stupor.","label":0,"label_text":"Not-Related"}
+{"text":"When enzyme levels in the proband and relatives were compared with that in controls, an autosomal recessive pattern of inheritance was demonstrated.","label":0,"label_text":"Not-Related"}
+{"text":"A p value < 0.05 was considered statistically significant.","label":0,"label_text":"Not-Related"}
+{"text":"The patient's previous rash and the temporal relation of this event and the ingestion of phenolphthalein, as well as the similarity of this case to other reports, point to phenolphthalein as the cause of TEN in this patient.","label":1,"label_text":"Related"}
+{"text":"At the third session of TACE, the right hepatic artery was found to be thrombosed; however, angiography also demonstrated collateral feeder vessels (arising from the pancreaticoduodenal artery) which were used for treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Gastric tumor, endometrial carcinoma and cervical adenocarcinoma in situ were detected after treatment with tamoxifen for breast cancer.","label":1,"label_text":"Related"}
+{"text":"Electrophysiologic evaluation demonstrated failure to terminate ventricular tachycardia with maximal energy shocks, but consistent termination by low energy discharges.","label":0,"label_text":"Not-Related"}
+{"text":"Ifosfamide-induced nonconvulsive status epilepticus.","label":1,"label_text":"Related"}
+{"text":"Diagnosis of attention-deficit\/hyperactivity disorder by family physicians and pediatricians was most commonly based on brief behavioral descriptions by parents and, infrequently, by use of rating scales.","label":0,"label_text":"Not-Related"}
+{"text":"Neutropenic colitis has been thought to be a serious gastrointestinal complication associated with chemotherapy for hematological malignancy.","label":0,"label_text":"Not-Related"}
+{"text":"A 26-year-old man developed painless inferior subepithelial infiltrates away from the site of ablation in both eyes after excimer laser photorefractive keratectomy (PRK) for myopia.","label":0,"label_text":"Not-Related"}
+{"text":"We report two patients with acquired fistulas between the internal mammary and pulmonary arteries after coronary bypass surgery.","label":0,"label_text":"Not-Related"}
+{"text":"Immuno-chemo-radiotherapy (interferon, ranimustine, and radiation), second-line chemotherapy (carboplatin and etoposide, 7 cycles) and third-line chemotherapy (ifosfamide, carboplatin, and etoposide) was given to treat progressive disease.","label":0,"label_text":"Not-Related"}
+{"text":"The patient who had been treated the longest and had received the highest total dose also had the highest SCE count.","label":0,"label_text":"Not-Related"}
+{"text":"Is pseudo-Cushing's syndrome in a critically ill patient \"pseudo\"? Hypothesis and supportive case report.","label":0,"label_text":"Not-Related"}
+{"text":"The plasma concentrations of procainamide and N-acetyl procainamide were at subtherapeutic levels.","label":0,"label_text":"Not-Related"}
+{"text":"Three patients with niacin-induced visual symptoms had cystoid maculopathy without leakage on fluorescein angiography, and a fourth patient with no fundus abnormality experienced cessation of visual symptoms upon discontinuation of niacin.","label":1,"label_text":"Related"}
+{"text":"The median survival was 22.1 months in all and 17.1 months in six patients with PVTT.","label":0,"label_text":"Not-Related"}
+{"text":"DISCUSSION: To our knowledge, this is the first case report illustrating neuralgic amyotrophy triggered by exposure to the antibiotics vancomycin, tobramycin, and piperacillin\/tazobactam.","label":1,"label_text":"Related"}
+{"text":"RESULTS: The response rate was 84.6%, with complete response in one patient and partial response (PR) in 10 patients.","label":0,"label_text":"Not-Related"}
+{"text":"Radiation therapy decreased the size of the mass, but five months later partial small bowel obstruction occurred because of recurrent lymphomatous infiltration.","label":0,"label_text":"Not-Related"}
+{"text":"3. Thus, the decreased plasma cortisol level during alprazolam treatment of panic disorder was suggested to be caused not by symptom alleviation due to alprazolam but by alprazolam administration itself.","label":1,"label_text":"Related"}
+{"text":"Two patients who were receiving Tolazoline by infusion developed duodenal ulceration and subsequent intestinal perforation.","label":1,"label_text":"Related"}
+{"text":"Sequential CT studies were performed in 24 patients with infantile spasms, before, during and after ACTH therapy, in order to analyze the relationship between the dose of ACTH and changes in CT scan findings.","label":0,"label_text":"Not-Related"}
+{"text":"Acetazolamide may have accelerated the development of osteomalacia by several mechanisms, including increased renal calcium excretion.","label":1,"label_text":"Related"}
+{"text":"An objective causality assessment by use of the Naranjo probability scale revealed that NCSE due to ifosfamide was probable.","label":1,"label_text":"Related"}
+{"text":"Nurses can be instrumental in minimizing the impact of these conditions by monitoring the longitudinal trends in Hb levels, proactively assessing patients for inflammatory or infectious conditions, and intervening to resolve causative conditions and minimize the impact on anemia.","label":0,"label_text":"Not-Related"}
+{"text":"Despite a response of the meningeal tumor the patient developed in the third week of MTX treatment a progressive visual loss and loss of consciousness which worsened during subsequent Ara-C treatment and led to death within 3 weeks.","label":1,"label_text":"Related"}
+{"text":"OBJECTIVE: To document a case of serotonin syndrome (SS) associated with mirtazapine monotherapy, review the previously reported cases of SS associated with this tetracyclic antidepressant, and discuss the possible pathogenic mechanisms leading to this serious adverse drug reaction.","label":1,"label_text":"Related"}
+{"text":"Hepatotoxicity related to itraconazole: report of three cases.","label":1,"label_text":"Related"}
+{"text":"We will also discuss the unusual nature of this type of burn and the course of phototoxic lesions and their differences from a typical sunburn.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case histories of identical twin brothers who developed concordant acute lymphoblastic leukemia at the age of 4 years and who later developed leukoencephalopathy and hydrocephalus related to central nervous system prophylaxis by, in the first case intrathecally administered methotrexate and, in the second by intrathecally administered methotrexate and cranial irradiation.","label":1,"label_text":"Related"}
+{"text":"Diagnosis was based on a history of repeated exposure to sulfonamides, skin biopsy findingd, and clinical recovery on cessation of sulfonamide therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Hyperperfusion syndrome is a well-documented clinical complication after endarterectomy and carotid stenting.","label":0,"label_text":"Not-Related"}
+{"text":"Therapy with IFN-alpha may be associated with a number of neuropsychiatric symptoms, such as Parkinsonism, akathisia, seizure, and depressive disorders.","label":1,"label_text":"Related"}
+{"text":"There was minimum toxicity reported for either of the arms and no treatment related deaths.","label":0,"label_text":"Not-Related"}
+{"text":"A prompt and accurate diagnosis is crucial.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was a borderline candidate for mechanical ventilation for 3 weeks.","label":0,"label_text":"Not-Related"}
+{"text":"In five of these cases the episode began after an unusually large dose, in three after a therapeutic one with a latency of about 24 hours.","label":0,"label_text":"Not-Related"}
+{"text":"We describe the case of acute hepatitis induced by gliclazide, a second generation sulfonylurea.","label":1,"label_text":"Related"}
+{"text":"Systemic absorption of oral vancomycin in a peripheral blood stem cell transplant patient with severe graft-versus-host disease of the gastrointestinal tract.","label":0,"label_text":"Not-Related"}
+{"text":"Renal function improved rapidly after withdrawal of the drug therapy.","label":0,"label_text":"Not-Related"}
+{"text":"An analysis of our patients, together with literature review of similar cases, suggests that the duration of chemotherapy may have been the most important factor in the leukemogenesis.","label":0,"label_text":"Not-Related"}
+{"text":"Increased ocular pressure in two patients with narrow angle glaucoma treated with venlafaxine.","label":1,"label_text":"Related"}
+{"text":"We report five cases of carboplatin (CBDCA) hypersensitivity after weekly low-dose paclitaxel (60 mg\/m2)\/CBDCA (area under the concentration curve = 2) therapy in patients with recurrent ovarian cancer receiving multiple platinum-based chemotherapy.","label":1,"label_text":"Related"}
+{"text":"Mequitazine is a phenothiazine derivative antihistamine.","label":0,"label_text":"Not-Related"}
+{"text":"Complete remission of the nephrosis occurred after discontinuation of hydroxychloroquine therapy.","label":1,"label_text":"Related"}
+{"text":"Anorexia in a 14-year-old girl: why won't she eat?","label":0,"label_text":"Not-Related"}
+{"text":"The ACE inhibitors can cause various skin side effects; however, it rarely causes cutaneous vasculitis.","label":0,"label_text":"Not-Related"}
+{"text":"The thigh and buttock muscles were \"wooden-hard\" on palpation.","label":0,"label_text":"Not-Related"}
+{"text":"These observations indicate that submassive hepatic necrosis may result from treatment with propylthiouracil and are consistent with the notion that sensitization mechanisms may be responsible for the hepatic injury induced by this drug.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: Intrathecal baclofen can impair sexual function and ejaculation in some patients.","label":1,"label_text":"Related"}
+{"text":"We describe a woman who received polyacrylamide gel injections for cosmetic reasons and developed a severe granulomatous inflammation paranasally.","label":0,"label_text":"Not-Related"}
+{"text":"A case of contact dermatitis due to sodium bisulfite in an ophthalmic solution.","label":1,"label_text":"Related"}
+{"text":"To discuss the possible mechanisms of action and highlight the potential detrimental effects of dipivefrin on palpebral conjunctiva.","label":0,"label_text":"Not-Related"}
+{"text":"Psychoendocrine sequelae of chronic testosterone deficiency.","label":0,"label_text":"Not-Related"}
+{"text":"We report a fatal case of toxic epidermal necrolysis (TEN) resulting from a high dose of cytosine arabinoside (ARA-C).","label":1,"label_text":"Related"}
+{"text":"Bleomycin and cyclophosphamide toxicity simulating metastatic nodules to the lungs in childhood cancer.","label":1,"label_text":"Related"}
+{"text":"Severe lidocaine intoxication by cutaneous absorption.","label":0,"label_text":"Not-Related"}
+{"text":"Central serous chorioretinopathy associated with inhaled or intranasal corticosteroids.","label":0,"label_text":"Not-Related"}
+{"text":"Immunosuppression with ciclosporin can be an effective and well-tolerated treatment for steroid-responsive sudden SNHL.","label":0,"label_text":"Not-Related"}
+{"text":"Anticoagulation was started, the OCP was discontinued, and a discussion occurred regarding the treatment options for her menorrhagia following her recent diagnosis.","label":0,"label_text":"Not-Related"}
+{"text":"None of the patients had a previous history of glaucoma, ocular hypertension or IOP asymmetry and the IOP was as high as 30, 34, 46, and 50 mmHg in the four patients.","label":0,"label_text":"Not-Related"}
+{"text":"Cerebral dural sinus thrombosis is an unusual syndrome in which a patient presents with a severe headache that may be associated with diverse neurologic and physical findings.","label":0,"label_text":"Not-Related"}
+{"text":"Here, we describe a case of Vogt-Koyanagi-Harada disease occurring 4 months after the start of interferon alpha treatment, probably induced by the immunomodulatory effects of interferon.","label":1,"label_text":"Related"}
+{"text":"We report a case of anterior uveitis after small-incision cataract surgery due to an intraocular ointment base.","label":0,"label_text":"Not-Related"}
+{"text":"Autopsies of four cases of toxic leukoencephalopathy were performed following standard protocols.","label":0,"label_text":"Not-Related"}
+{"text":"In such patients the drug is withdrawn and replaced by another medication.","label":0,"label_text":"Not-Related"}
+{"text":"ARDS is rarely associated with rituximab infusion for lympho-proliferative disorders, but it should be considered by those administering rituximab, especially when a patient develops severe pulmonary symptoms soon after infusion.","label":1,"label_text":"Related"}
+{"text":"The patient's metastatic disease remained stable for the next 2 years.","label":0,"label_text":"Not-Related"}
+{"text":"Test and teach.","label":0,"label_text":"Not-Related"}
+{"text":"We report on a 37-year-old female who complained of moderate hair loss during paroxetine treatment.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION-It is possible to prevent GH from PHT treatment by intensive dental care, correct mouth hygiene and by change of treatment of carbamazepine.","label":0,"label_text":"Not-Related"}
+{"text":"Plasma drug concentrations were largely kept within the therapeutic range but wide variability was observed on oral therapy.","label":0,"label_text":"Not-Related"}
+{"text":"A 29-year-old woman with a long history of primary nocturnal enuresis began treatment with intranasal desmopressin.","label":0,"label_text":"Not-Related"}
+{"text":"The tube was removed by external traction, without any abdominal incision, and a different site was used for the insertion of a new percutaneous endoscopic gastrostomy tube.","label":0,"label_text":"Not-Related"}
+{"text":"A 14-year-old girl presented with severe haemorrhagic diathesis.","label":0,"label_text":"Not-Related"}
+{"text":"Adults with immunosuppression should receive prompt systemic treatment with acyclovir.","label":0,"label_text":"Not-Related"}
+{"text":"The biochemistry of paracetamol hepatotoxicity is outlined and the increased susceptibility of alcoholic patients to the hepatotoxic effects of paracetamol is remarked upon.","label":1,"label_text":"Related"}
+{"text":"Five of 610 adults developed chickenpox between 35 days and 9.2 years after renal transplantation, and only one patient survived.","label":0,"label_text":"Not-Related"}
+{"text":"In conclusion, even if in our case no surgical treatment was used and although spontaneous resorption has been described for some materials, early surgical exploration with removal of the material and decompression of the IAN is suggested, irrespective of the material used, because the severity of nerve damage can increase with the duration of the injury.","label":0,"label_text":"Not-Related"}
+{"text":"Recently, atypical antipsychotics have been more widely used in the treatment of behavioral and psychological symptoms with dementia (BPSD) than conventional neuroleptics because of a reduced tendency for movement disorders and psychomotor retardation.","label":0,"label_text":"Not-Related"}
+{"text":"Two courses of tinidazole (the second in combination with percutaneous aspiration of the abscess) were required to achieve cure.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was diagnosed with carbamazepine toxicity related to the introduction of ritonavir.","label":1,"label_text":"Related"}
+{"text":"RESULTS: Four pediatric patients (2 males and 2 females) with mean age of 14.5 years (range 11-18 years) were studied.","label":0,"label_text":"Not-Related"}
+{"text":"All patients tolerated the treatment well with no residual effects from the electric pulses.","label":0,"label_text":"Not-Related"}
+{"text":"UFT, a combination of uracil and tegafur, is a second-generation anticancer agent.","label":0,"label_text":"Not-Related"}
+{"text":"The beneficial effect of the long-acting analogue of somatostatin SMS 201-995 in the treatment of acromegaly is described in three cases, and current published experience is reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"Although nondiphtherial corynebacteria are ubiquitous in nature and commonly colonize the skin and mucous membranes of humans, they rarely account for clinical infection.","label":0,"label_text":"Not-Related"}
+{"text":"Proponents of the use of fluoroscopy cite studies that report up to 35% rates of inaccurate placement of epidural needles without the aid of fluoroscopic imaging.","label":0,"label_text":"Not-Related"}
+{"text":"She developed gastrointestinal, central nervous system, cardiovascular and haematological disturbances.","label":0,"label_text":"Not-Related"}
+{"text":"Our report suggested that CBDCA hypersensitivity was correlated with the total dose of previously administered platinum agents and that CBDCA should be excluded in patients who have received multiple platinum-based chemotherapy, even in platinum-sensitive cases, because CBDCA hypersensitivity can occur even with low-dose CBDCA administration.","label":1,"label_text":"Related"}
+{"text":"It is suggested that hasty correction of thyrotoxicosis should be avoided in susceptible patients, unless the thyrotoxic conditions are critical.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVES: To describe clinical and pathologic findings in patients noted to develop lower gastrointestinal symptoms when exposed to rofecoxib.","label":1,"label_text":"Related"}
+{"text":"He also showed a large tongue with an anterior open bite.","label":0,"label_text":"Not-Related"}
+{"text":"A complete ocular examination, fluorescein angiography, carotid artery Doppler sonography and brain magnetic resonance imaging were performed.","label":0,"label_text":"Not-Related"}
+{"text":"CP is classified as a pregnancy risk factor D drug and is teratogenic in animals, but population studies have not conclusively demonstrated teratogenicity in humans.","label":0,"label_text":"Not-Related"}
+{"text":"An alternative preparation, methylprednisolone, was used to successfully treat her underlying condition.","label":0,"label_text":"Not-Related"}
+{"text":"High-flux haemodialysis treatment as treatment for carbamazepine intoxication.","label":0,"label_text":"Not-Related"}
+{"text":"An allergic reaction to a drug's additive material should be considered as a rare cause of drug-induced acute eosinophilic pneumonia.","label":0,"label_text":"Not-Related"}
+{"text":"Persistent idiopathic facial pain following dental implant placement: a case report.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Routine histology confirmed the clinical diagnosis of oral lichen planus-like c-GVHD.","label":0,"label_text":"Not-Related"}
+{"text":"Subsequently, when ferrous sulfate was discontinued, the patient became hyperthyroid while taking the higher dose of thyroid hormone preparation.","label":0,"label_text":"Not-Related"}
+{"text":"The dialyzer circuit did not clot during the argatroban infusion and did not apparently influence dose-related aPTT measurements.","label":0,"label_text":"Not-Related"}
+{"text":"The third patient developed liver and marrow toxicity on day 3 and died on day 9.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a continuous ambulatory peritoneal dialysis (CAPD) patient that developed vancomycin-induced agranulocytosis during treatment for methicillin-resistant Staphylococcus aureus (MRSA)-associated external cuff infection and pneumonia.","label":1,"label_text":"Related"}
+{"text":"Baseline measurements of anterior chamber depth and lens thickness were obtained.","label":0,"label_text":"Not-Related"}
+{"text":"Despite chemotherapy, the patient died 2 months after the diagnosis.","label":0,"label_text":"Not-Related"}
+{"text":"CYP2D6 gene deletion allele in patients with neuroleptic malignant syndrome: preliminary report.","label":0,"label_text":"Not-Related"}
+{"text":"The symptoms were attributed to hepatitis B vaccination.","label":0,"label_text":"Not-Related"}
+{"text":"Posterior reversible encephalopathy syndrome associated with methotrexate neurotoxicity: conventional magnetic resonance and diffusion-weighted imaging findings.","label":1,"label_text":"Related"}
+{"text":"The underlying pathogenesis is probably multifactorial.","label":0,"label_text":"Not-Related"}
+{"text":"PAIN Control: IV opioid range orders for acute pain management.","label":0,"label_text":"Not-Related"}
+{"text":"This is a report concerning a patient in whom a continuous infusion of dexmedetomidine was safely used for a week to help in averting frank withdrawal symptoms from an opioid and benzodiazepines.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients treated with 5-fluorouracil (5-FU) for disseminated adenocarcinoma of the colon developed cerebellar dysfunction typical of 5-FU neurotoxicity.","label":1,"label_text":"Related"}
+{"text":"In two dogs the lesions resolved after 7.5-8.5 months of immune-suppressive treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Osteonecrosis is not well documented as a predisposing factor of septic arthritis despite such a relationship having obvious clinical significance.","label":0,"label_text":"Not-Related"}
+{"text":"The sulfonamides are the best verified drug-trigger for erythema multiforme and Stevens-Johnson syndrome.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: The choice of anticoagulant and antiplatelet agents, dose, and timing of administration can affect outcomes in patients with NSTE ACS.","label":0,"label_text":"Not-Related"}
+{"text":"In one patient the vasculitis resolved after termination of the ciprofloxacin therapy; in the other patient the ciprofloxacin-induced hemorrhagic vasculitis was superimposed on a severe forefoot infection, leading to progressive gangrene and a below-knee amputation.","label":1,"label_text":"Related"}
+{"text":"RESULTS: A 60-year-old woman with chronic active viral C hepatitis (HCV genotype = 3a) started IFN-alpha therapy in November '96.","label":0,"label_text":"Not-Related"}
+{"text":"These findings are compatible with PVOD.","label":0,"label_text":"Not-Related"}
+{"text":"Severe lactic acidosis related to acute thiamine deficiency.","label":0,"label_text":"Not-Related"}
+{"text":"Rhino-orbital zygomycosis secondary to Rhizopus oryzae in a renal transplant recipient successfully treated with liposomal amphotericin B.","label":0,"label_text":"Not-Related"}
+{"text":"Histopathology of maculae showed extensive collections of melanophages in the upper dermis.","label":0,"label_text":"Not-Related"}
+{"text":"Sensory neuropathy revealing necrotizing vasculitis during infliximab therapy for rheumatoid arthritis.","label":1,"label_text":"Related"}
+{"text":"In this case, an evaluation for organism-specific pathology led to early identification of a potentially curable large bowel lesion.","label":0,"label_text":"Not-Related"}
+{"text":"Improvement both clinically and by objective assessment, was observed on intravenous CyA therapy, but was not sustained when the drug was given orally for several months.","label":0,"label_text":"Not-Related"}
+{"text":"Examination revealed facial erythema and eczema, ectropion, blepharitis, chemosis, lid teleangectasia, and contact lens-related corneal edema.","label":0,"label_text":"Not-Related"}
+{"text":"Further benefit was gained from a course of calcitonin.","label":0,"label_text":"Not-Related"}
+{"text":"She was diagnosed with Epstein-Barr virus-associated polymorphic lymphoproliferative disorder (LPD) due to immunodeficiency caused by MTX administration.","label":1,"label_text":"Related"}
+{"text":"After treatment with topical corticosteroids, antiglaucoma agents, cycloplegics, hypertonic saline and tears supplements, 27 (93%) eyes recovered completely within 3-14 days.","label":0,"label_text":"Not-Related"}
+{"text":"The combination of raltitrexed (Tomudex) and mitomycin-C in the treatment of advanced colorectal cancer--a phase II study.","label":0,"label_text":"Not-Related"}
+{"text":"Eleven weeks later he developed Pneumocystis carinii pneumonia.","label":0,"label_text":"Not-Related"}
+{"text":"Pamidronate was used and calcium concentrations normalized by 24 hours after treatment.","label":0,"label_text":"Not-Related"}
+{"text":"While the tyrosine kinase inhibitor imatinib, which has been recently shown to represent the treatment of choice for GIST, is primarily metabolized by the liver, data on the pharmacokinetics and the tolerability of imatinib in patients with increased cholestasis parameters are not yet available.","label":0,"label_text":"Not-Related"}
+{"text":"The patient with a pre-excitation syndrome is usually managed in a coronary care unit.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Both the immunomodulatory effects of octreotide on intrathyroidal lymphocytes and rapid reductions in TSH may contribute to the onset of Graves' disease.","label":0,"label_text":"Not-Related"}
+{"text":"A patient suffering from heparin-associated thrombocytopenia (HAT), recurrent arteriothromboses, and acute renal failure after treatment with standard heparin is described.","label":1,"label_text":"Related"}
+{"text":"The literature on garlic burns is reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"We report a patient with inoperable pancreatic cancer who developed gastrointestinal bleeding secondary to radiation-recall related to gemcitabine and review literature.","label":1,"label_text":"Related"}
+{"text":"A study of the absorption and disappearance of dexamethasone from the circulation in response to a (1 mg oral dose indicated that the steroid was absorbed normally but was cleared more rapidly from the circulation of these two patients than from normal controls.","label":0,"label_text":"Not-Related"}
+{"text":"Retinal abnormalities, including retinal hemorrhage and \"cotton-wool\" spots, often occur within the first 8 weeks in the course of interferon therapy in patients with chronic hepatitis C.","label":1,"label_text":"Related"}
+{"text":"Discontinuation of these two antibiotics results in an immediate decline of the thrombocyte count to normal values within three weeks.","label":0,"label_text":"Not-Related"}
+{"text":"Although the association between SJS\/TEN and the sulfonamide class of antibiotics is well established, the increasing prevalence of CA-MRSA has left practitioners with limited regimens to effectively treat skin and soft tissue infections (SSTIs) in the outpatient setting.","label":0,"label_text":"Not-Related"}
+{"text":"Propoxyphene overdose is known to cause widening of the QRS complex on ECG.","label":0,"label_text":"Not-Related"}
+{"text":"Total lithotomy time was four hours.","label":0,"label_text":"Not-Related"}
+{"text":"Amiodarone-induced thyrotoxicosis associated with thyrotropin receptor antibody.","label":1,"label_text":"Related"}
+{"text":"We also review the diagnostic and therapeutic implications of this paradoxical complication associated with treatment of bone lesions in MM.","label":0,"label_text":"Not-Related"}
+{"text":"Serum free levels and evaluation anticonvulsant drug interactions.","label":0,"label_text":"Not-Related"}
+{"text":"Multiple hepatic tumors and peliosis hepatis in Fanconi's anemia treated with androgens.","label":0,"label_text":"Not-Related"}
+{"text":"Both patients developed hypoadrenalism while on o,p'-DDD and apparently adequate dexamethasone replacement therapy.","label":1,"label_text":"Related"}
+{"text":"Depression is a common problem in elderly patients and frequently is treated with antidepressants.","label":0,"label_text":"Not-Related"}
+{"text":"A 62-year-old Japanese man who was positive for hepatitis B surface antigen (HBsAg) and anti-HBe antibody, underwent chemotherapy for non-Hodgkin's lymphoma (NHL).","label":0,"label_text":"Not-Related"}
+{"text":"We conclude that opiate medication may inhibit - in a life-threatening way - the organism's ability to respond to physical, emotional or metabolic stressors.","label":0,"label_text":"Not-Related"}
+{"text":"A 68-year-old female with mild diabetes mellitus was admitted because of acute liver dysfunction due to autoimmune hepatitis.","label":0,"label_text":"Not-Related"}
+{"text":"Disseminated intravascular coagulation associated with acute hemoglobinemia or hemoglobinuria following Rh(0)(D) immune globulin intravenous administration for immune thrombocytopenic purpura.","label":1,"label_text":"Related"}
+{"text":"DISCUSSION: Acute ITB withdrawal syndrome occurs frequently in cases of malfunctioning intrathecal infusion pumps or catheters.","label":0,"label_text":"Not-Related"}
+{"text":"Further study revealed that all three patients had low plasma renin activity and nonsuppresible plasma aldosterone levels after saline infusion.","label":0,"label_text":"Not-Related"}
+{"text":"In addition, the patients did not demonstrate evidence of hypothalamic-pituitary-adrenal axis suppression.","label":0,"label_text":"Not-Related"}
+{"text":"The literature on human aflatoxicosis shows that the presentation may be acute, subacute and chronic.","label":0,"label_text":"Not-Related"}
+{"text":"STUDY DESIGN: A case report.","label":0,"label_text":"Not-Related"}
+{"text":"Reviewing data on these patients and recent literature indicate that fatal marrow aplasia seems to occur more frequently in sero-negative women who respond well to therapy with gold salts.","label":0,"label_text":"Not-Related"}
+{"text":"He received further chemotherapy without G-CSF and without any recurrence of the raised leucocyte count but failed to achieve full remission.","label":0,"label_text":"Not-Related"}
+{"text":"MRI revealed signal abnormalities within the corpus callosum, basal ganglia, and brainstem.","label":0,"label_text":"Not-Related"}
+{"text":"This article presents a patient with hypoparathyroidism who was treated with calcium carbonate and calcitriol resulting in two admissions to the hospital for milk-alkali syndrome.","label":1,"label_text":"Related"}
+{"text":"On rechallenge she developed severe dyspnea, cough, and wheezing 20 minutes after administration.","label":0,"label_text":"Not-Related"}
+{"text":"Complete clinical resolution was observed with oral and topical antimycotic treatment.","label":0,"label_text":"Not-Related"}
+{"text":"A final dosage of 60 mg\/kg was used.","label":0,"label_text":"Not-Related"}
+{"text":"It is recommended that patients be diligently screened before starting TNF-alpha antagonist therapy and that vigilance for symptoms of demyelinating disease\/multiple sclerosis be included in follow-up examinations during treatment with these drugs.","label":0,"label_text":"Not-Related"}
+{"text":"STUDY DESIGN: A case report.","label":0,"label_text":"Not-Related"}
+{"text":"The mechanism of the electrocardiogram changes was considered to be caused by the two drugs synergistic sodium channel blocking effects.","label":0,"label_text":"Not-Related"}
+{"text":"Treating stridor with opioids: a challenging case of paradoxical vocal cord movement.","label":0,"label_text":"Not-Related"}
+{"text":"Amphotericin B (AmB) is effective, but its use is limited by toxicity: renal impairment, anaemia, fever, malaise, and hypokalaemia are common.","label":1,"label_text":"Related"}
+{"text":"This case highlights the need to monitor liver enzymes in patients treated with 6-TG and identifies the need for additional research focused on the mechanism of thiopurine-induced hepatic injury.","label":1,"label_text":"Related"}
+{"text":"Reversible valproic acid-induced dementia was documented in a 21-year-old man with epilepsy who had a 3-year history of insidious progressive decline in global cognitive abilities documented by serial neuropsychological studies.","label":1,"label_text":"Related"}
+{"text":"Pneumonitis and pneumatoceles following accidental hydrocarbon aspiration in children.","label":0,"label_text":"Not-Related"}
+{"text":"Although this drug interaction is well established in the literature, we found no documented cases that address its effects on anticoagulation parameters in patients requiring repeated cycles of 5-fluorouracil and continuous warfarin therapy.","label":0,"label_text":"Not-Related"}
+{"text":"The patient had already been on methimazole for a month when she was admitted to the Pediatric Unit with the diagnosis of sepsis.","label":0,"label_text":"Not-Related"}
+{"text":"AIMS: To investigate a worker who experienced systemic and respiratory symptoms when exposed to a vanadium containing powder used as a catalyst in the production of maleic anhydride.","label":0,"label_text":"Not-Related"}
+{"text":"Tonic status epilepticus presenting as confusional state.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a premenopausal woman who, while having tamoxifen due to a diagnosis of in situ ductal carcinoma, developed endometriosis requiring surgery.","label":1,"label_text":"Related"}
+{"text":"Blood, urine, and throat cultures were negative.","label":0,"label_text":"Not-Related"}
+{"text":"The patient's INR increased 11-14 days after each cycle of chemotherapy with 5-fluorouracil and leucovorin.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: Repeated blood samples were drawn in a patient with severe acyclovir overdose who developed coma and nonoliguric renal failure.","label":1,"label_text":"Related"}
+{"text":"The increasing incidence of both atrial fibrillation and colon cancer with age could potentially require the concomitant use of 5-FU, levamisole, and warfarin.","label":0,"label_text":"Not-Related"}
+{"text":"Surgically induced necrotizing scleritis in a patient with ankylosing spondylitis.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Interferon (IFN)-associated retinopathy is typically characterized by retinal hemorrhages and cotton wool spots at the posterior fundus, but visual function is usually maintained.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: A possible pharmacokinetic interaction between Dantrolene and Oxybutynin should be borne in mind when considering Carbamazepine medication for a patient with a spinal cord lesion.","label":0,"label_text":"Not-Related"}
+{"text":"DISCUSSION: Eye burns followed by calcifications follow two different major patterns: the corrosive substance contained calcium or the continued therapy was applied with phosphate-buffered eye drops.","label":0,"label_text":"Not-Related"}
+{"text":"He was referred after a percutaneous liver biopsy which revealed a moderately differentiated HCC.","label":0,"label_text":"Not-Related"}
+{"text":"It is imperative that dermatologists have a keen awareness of this possible adverse event given the increased use of this class of drugs.","label":0,"label_text":"Not-Related"}
+{"text":"Linezolid may be a good alternative for treatment of ventriculoperitoneal shunt infections in cases of vancomycin-resistant organisms or apparent treatment failures.","label":0,"label_text":"Not-Related"}
+{"text":"In addition, loading with one low oral dose of serine produced psychotic symptoms 5 h later which lasted 3-6 h.","label":1,"label_text":"Related"}
+{"text":"He had previously received several treatments including two courses of fludarabine.","label":0,"label_text":"Not-Related"}
+{"text":"We describe two patients with rheumatoid factor-positive, polyarticular-onset juvenile rheumatoid arthritis in whom accelerated nodulosis developed during methotrexate therapy.","label":1,"label_text":"Related"}
+{"text":"Acute elevation of the ST segment in several ECG leads was observed in seven patients with bacterial shock during the course of therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Intraocular pressure (IOP) was not able to be controlled medically, however, and filtering surgery 20 days post laser treatment was required.","label":0,"label_text":"Not-Related"}
+{"text":"To our knowledge, this is the first report of t-MDS with der(17)t(12;17)(q13;p13) after treatment for CLL.","label":0,"label_text":"Not-Related"}
+{"text":"Central venous catheter-related Rhodotorula rubra fungemia.","label":0,"label_text":"Not-Related"}
+{"text":"This observation suggest that linezolid is a promising drug for the treatment of prosthetic joint infections due to MRSA or other Gram-positive pathogens, particularly when other therapeutic approaches are not feasible or a long-term antibiotic therapy is required.","label":0,"label_text":"Not-Related"}
+{"text":"In each instance, the plasma thrombosis-inducing activity (TIA) appeared one to three days after chemotherapy and subsided subsequently.","label":0,"label_text":"Not-Related"}
+{"text":"Five cases of clindamycin-associated pseudomembranous colitis in leukaemic patients are reported.","label":1,"label_text":"Related"}
+{"text":"No reactions occurred to methylprednisolone and hydrocortisone.","label":0,"label_text":"Not-Related"}
+{"text":"Only papers published in English were reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"Severe visual loss after a single dose of vincristine in a patient with spinal cord astrocytoma.","label":1,"label_text":"Related"}
+{"text":"Small intestinal resection with loss of small intestinal absorptive area was not a risk factor for the development of osteonecrosis.","label":0,"label_text":"Not-Related"}
+{"text":"Chloroquine treatment remains the most common single treatment of malaria in sub-Saharan Africa.","label":0,"label_text":"Not-Related"}
+{"text":"A 73-year-old man with two previous mitral valve replacements presented with prosthetic valve infective endocarditis.","label":0,"label_text":"Not-Related"}
+{"text":"Graft versus host-like illness in a child with phenobarbital hypersensitivity.","label":1,"label_text":"Related"}
+{"text":"We studied 13 healthy volunteer subjects, performing three hepatobiliary scans in each one.","label":0,"label_text":"Not-Related"}
+{"text":"Because these changes may be effects of parathyroid hormone (PTH), PTH was measured in 19 patients receiving lithium.","label":0,"label_text":"Not-Related"}
+{"text":"Assessment of cortisol response was by insulin-induced hypoglycaemia in three cases, by short tetracosactrin test in two, and by low-dose tetracosactrin and 24-hour urinary cortisol\/creatinine ratio in one.","label":1,"label_text":"Related"}
+{"text":"We describe two patients who developed malignant myelosclerosis after receiving cytotoxic chemotherapy, one for Hodgkin's disease, and the other for membranous nephritis.","label":0,"label_text":"Not-Related"}
+{"text":"Considering that this article provides findings from a single patient, the authors use this experience to discuss and emphasize the importance of clinical control of barbiturates in psychiatry.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: Anterior ischemic optic neuropathy may complicate treatment with interferon alfa.","label":1,"label_text":"Related"}
+{"text":"Use of the Naranjo adverse drug reaction probability scale indicated a probable association between this patient's reduced A1C levels and erythropoietin therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Our analysis reveals that this method is useful, but also highlights potential areas for its improvement.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Dual desensitization resulted in marked improvement in her symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"Multiple keratoacanthomas developed on the face of a woman after radiation therapy to the nasal sinuses.","label":0,"label_text":"Not-Related"}
+{"text":"Horner's syndrome and demyelinating peripheral neuropathy caused by high-dose cytosine arabinoside.","label":1,"label_text":"Related"}
+{"text":"The treatment of Toxoplasma encephalitis in patients with acquired immunodeficiency syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Methotrexate-induced leukoencephalopathy is treatable with high-dose folinic acid: a case report and analysis of the literature.","label":1,"label_text":"Related"}
+{"text":"The lesion was recurrent, with evidence of desquamation.","label":0,"label_text":"Not-Related"}
+{"text":"This case report underscores the relationship between genetic background, environmental factors, drug-induced immunosuppression and the evolution of this peculiar neoplasm.","label":0,"label_text":"Not-Related"}
+{"text":"Limited data suggest that TNF-alpha inhibitors may facilitate uncontrolled hepatitis B viral replication.","label":0,"label_text":"Not-Related"}
+{"text":"Severe akathisia during olanzapine treatment of acute schizophrenia.","label":1,"label_text":"Related"}
+{"text":"Neither our patient's clinical symptoms nor her serologic parameters improved possibly because of the low dosage and\/or short duration of cyclosporine A treatment.","label":0,"label_text":"Not-Related"}
+{"text":"We present the clinical history\/presentation investigation and the outcome of the treatment.","label":0,"label_text":"Not-Related"}
+{"text":"We describe two dark-skinned patients who developed hyperpigmented skin and tongue lesions during combination therapy with IFN and ribavirin.","label":1,"label_text":"Related"}
+{"text":"However, an increasing number of reports are appearing suggesting more than just a casual relationship between leukemia and the use of alkylating agents.","label":0,"label_text":"Not-Related"}
+{"text":"A rating system to display the effect of clozapine on individual parameters as well as on the over-all state was devised for this study.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: A 54-year-old muscular, short-statured man underwent posterior cervical laminectomy from C3-C5 without instrumentation and left C5 foraminotomy.","label":0,"label_text":"Not-Related"}
+{"text":"Toxic epidermal necrolysis after the use of high-dose cytosine arabinoside.","label":1,"label_text":"Related"}
+{"text":"PURPOSE: To report the occurrence of focal segmental glomerulosclerosis (FSGS) in children with acute lymphocytic leukemia (ALL), discuss pathogenesis and problems in management.","label":0,"label_text":"Not-Related"}
+{"text":"After adequate hydration and administration of oral colchicines, the patient's right knee pain subsided and the uric acid serum level returned to normal.","label":0,"label_text":"Not-Related"}
+{"text":"The sensory overstimulation is characterized by a subjective experience of sensory overload and a relative resistance to lidocaine local anesthesia.","label":0,"label_text":"Not-Related"}
+{"text":"Prothipendylhydrochloride-induced priapism: case report.","label":1,"label_text":"Related"}
+{"text":"Nevirapine is a non-nucleoside reverse transcriptase inhibitor widely used in combination with other antiretroviral agents for the treatment of HIV infection.","label":0,"label_text":"Not-Related"}
+{"text":"Alopecia, nausea, and vomiting were attributed to the cyclophosphamide component of the therapy.","label":1,"label_text":"Related"}
+{"text":"No patient had a history of previous chronic lung disease; most were not immunocompromised.","label":0,"label_text":"Not-Related"}
+{"text":"The mechanisms responsible for these conditions currently remain unclear.","label":0,"label_text":"Not-Related"}
+{"text":"This may also represent an alternative to ex-vivo expansion and deserves further investigation.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients were supported with a right VAD, one with a left VAD, and one with a biventricular VAD.","label":0,"label_text":"Not-Related"}
+{"text":"The serious clinical state of NE patients requires very frequent surgical consultations; however, in a few particular cases of NE, e.g., perforation of the bowels, a surgical intervention is necessary.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: The investigations were carried out on 186 liver biopsies and 5 autopsies.","label":0,"label_text":"Not-Related"}
+{"text":"We present an example of this complication that we recently saw in our department which on initial presentation appeared to be squamous cell carcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Myasthenia gravis (MG) is a neuromuscular disease sometimes associated with severe psychiatric complications.","label":0,"label_text":"Not-Related"}
+{"text":"A case report.","label":0,"label_text":"Not-Related"}
+{"text":"Skin rash and splinter hemorrhages from ganciclovir.","label":1,"label_text":"Related"}
+{"text":"Warfarin (coumadin) is the most common oral anticoagulant used for chronic anticoagulant therapy and most patients requiring such therapy are elderly (greater than 65 years old).","label":0,"label_text":"Not-Related"}
+{"text":"Calcification and ossification of the spinal arachnoid after intrathecal administration of Depo-Medrol.","label":1,"label_text":"Related"}
+{"text":"Hereby we describe the first case of ARF in a HIV-infected patient, who received IVIG stabilized with maltose for the treatment of HIV-related thrombocytopenic purpura.","label":0,"label_text":"Not-Related"}
+{"text":"Serial lymph node biopsies showed the progression of this disorder from a pleomorphic immunoblastic proliferation to a lymphocyte-depleted, fibrotic process, in parallel with a decline from hyper- to hypogammaglobulinemia.","label":0,"label_text":"Not-Related"}
+{"text":"Although the management of catheter-related Rhodotorula fungemia infections remains controversial, resolution of the underlying disease is more important than catheter removal for recovery from Rhodotorula rubra fungemia.","label":0,"label_text":"Not-Related"}
+{"text":"When infection of the instrumented cage is diagnosed, emergency debridement with or without removal of implants, including the cage, appropriate wound closure, and the administration of potent antibiotics is the standard treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Staphylococcus species, Streptococcus species, and less commonly, gram-negative rods comprise the majority of isolated organisms.","label":0,"label_text":"Not-Related"}
+{"text":"An organic mental syndrome developed in a patient soon after he underwent repair of a dissecting thoracic aortic aneurysm.","label":0,"label_text":"Not-Related"}
+{"text":"SS was diagnosed using the Hunter Criteria (use of multiple serotonergic drugs preoperatively, hypertonia, and spontaneous clonus) and was presumed to have been triggered by the combination of perioperative and intraoperative serotonergic medications.","label":0,"label_text":"Not-Related"}
+{"text":"On admission to the hospital, the patient was diagnosed and treated as having cholangitis.","label":0,"label_text":"Not-Related"}
+{"text":"In both cases, benefit of therapy with cetuximab could be demonstrated.","label":0,"label_text":"Not-Related"}
+{"text":"She developed a generalized rash and itching, sore throat, and dizziness approximately 4 hours after the first dose of capecitabine.","label":1,"label_text":"Related"}
+{"text":"Liver biopsy revealed a reduction in activity of carbamyl phosphate synthetase-I, an enzyme obligated for transformation of ammonia to urea in the urea cycle.","label":0,"label_text":"Not-Related"}
+{"text":"Both developed acute erythroid leukemia, 98 and 71 months after the original diagnosis of myeloma, and died of subarachnoid hemorrhage and cardiac arrest.","label":0,"label_text":"Not-Related"}
+{"text":"These results suggest that the pathogenesis of pseudotumor cerebri might be associated with the hypercoagulable state which was induced by glucocorticoid therapy and nephrotic syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"In 1 case the drug appears to have exacerbated underlying myasthenic weakness, whereas in the other 3 cases, de novo antibody formation appears to be most likely.","label":0,"label_text":"Not-Related"}
+{"text":"Pentavalent antimony is still the drug of choice in the treatment of visceral leishmaniasis.","label":0,"label_text":"Not-Related"}
+{"text":"Patients should be monitored for these potentially serious side-effects while on this drug.","label":0,"label_text":"Not-Related"}
+{"text":"The majority of patients were men and had a relatively early onset of parkinsonian symptomatology.","label":0,"label_text":"Not-Related"}
+{"text":"Purple glove syndrome, named for its distinctive purple discoloration and swelling of the hands in the distribution of a glove, is an uncommon complication of intravenous phenytoin administration through small dorsal veins of the hands.","label":1,"label_text":"Related"}
+{"text":"Under prophylactic treatment with low-dose trimipramine (50 mg) or nefazodone (200 mg\/day) therapy with IFN-alpha 3 x 3 mio IE\/week was re-established after several months and again 2 years later adding ribavirin 1200 mg\/day, a virustaticum.","label":0,"label_text":"Not-Related"}
+{"text":"Seven of 8 evaluable patients remain alive and free of recurrence with a median follow-up of 13 months.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a case of intraoperative gelatine-induced anaphylaxis whose diagnosis was delayed as the use of gelatine during surgical procedures was omitted for two times in patient's medical records.","label":1,"label_text":"Related"}
+{"text":"Data from the Cincinnati Transplant Tumor Registry indicate that of 662 patients treated for posttransplant lymphoma, 277 patients died of cancer and 137 died of other causes, of which infection was a major factor.","label":0,"label_text":"Not-Related"}
+{"text":"A failure to rely on serum free levels of the anti-convulsant under these circumstances can easily result in poor clinical decisions.","label":0,"label_text":"Not-Related"}
+{"text":"Protamine sulphate for treatment of severe post-reperfusion coagulopathy in pediatric liver transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"The peritoneal dialysis catheter was removed in 53% of cases, although this was rarely considered necessary for cure of tuberculosis.","label":0,"label_text":"Not-Related"}
+{"text":"Most electrophysiological responses were usually just within normal limits; two patients had subnormal Arden electro-oculography indices; and one patient showed an abnormally delayed photopic b wave.","label":0,"label_text":"Not-Related"}
+{"text":"A short course of treatment with topical aluminum chloride resulted in a remarkable response in 1 week.","label":0,"label_text":"Not-Related"}
+{"text":"Arrhythmias are the most common major complications encountered during pediatric cardiac catheterizations.","label":0,"label_text":"Not-Related"}
+{"text":"Development of platinum hypersensitivity can limit therapeutic options.","label":0,"label_text":"Not-Related"}
+{"text":"A preliminary study of a combination of pentoxifylline (PTX) and tocopherol (vit-E) has shown clinical activity with 50% superficial RIF regression at 6 months in half of the patients studied.","label":0,"label_text":"Not-Related"}
+{"text":"The current report describes a man who was prescribed zonisamide for epilepsy and subsequently developed widespread skin rash, acute kidney injury, high-grade fever, eosinophilia, liver dysfunction, lymphadenopathy and an increase in antihuman herpesvirus-6 immunoglobulin G titer.","label":1,"label_text":"Related"}
+{"text":"Polyarthritis, hepatitis and anti-native DNA antibodies after treatment with ethambutol and rifampicin.","label":1,"label_text":"Related"}
+{"text":"Use of tumor necrosis factor-alpha inhibitors in patients with chronic hepatitis B infection.","label":0,"label_text":"Not-Related"}
+{"text":"She was admitted following a fall and, after being given metoclopramide, developed movement disorder and a period of unresponsiveness.","label":1,"label_text":"Related"}
+{"text":"Our cases constitute the most severe cases of benzarone hepatotoxicity reported so far, and comprise the first cases of (sub)fulminant hepatitis and cirrhosis related to benzarone.","label":1,"label_text":"Related"}
+{"text":"Progression of the clinical picture was documented over 15 years of follow-up.","label":0,"label_text":"Not-Related"}
+{"text":"However, even with an initial dose of 0.5 mg, hypotension with consciousness disturbance developed in three hypertensive patients with recent cerebral hemorrhage.","label":0,"label_text":"Not-Related"}
+{"text":"Of the 10 patients with MDS, 6 were suffering from refractory anaemia with sideroblasts (RAS) and 4 from refractory anaemia with an excess of blasts.","label":0,"label_text":"Not-Related"}
+{"text":"Tamoxifen exhibits agonistic properties on the uterus.","label":0,"label_text":"Not-Related"}
+{"text":"Linear IgA bullous dermatosis occurring after carbamazepine.","label":1,"label_text":"Related"}
+{"text":"The left C4 pedicle screw was proven to breach the transverse foramen.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: The administration of tissue plasminogen activator was responsible for the large extent of hemorrhage and should be considered in the differential diagnosis of hemorrhagic choroidal detachment.","label":1,"label_text":"Related"}
+{"text":"A review of the literature is also presented.","label":0,"label_text":"Not-Related"}
+{"text":"A 7-year-old girl developed diabetes mellitus and exocrine pancreatic insufficiency after 3.5 years of almost continuous treatment with azathioprine and\/or prednisone for idiopathic auto-immune haemolytic anaemia.","label":1,"label_text":"Related"}
+{"text":"Total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed.","label":0,"label_text":"Not-Related"}
+{"text":"A woman with Cushing's syndrome after use of an Indonesian herb: a case report.","label":0,"label_text":"Not-Related"}
+{"text":"Pharmacists need to be vigilant in establishing a dialogue with their patients about the pros and cons of herbal product use, particularly with prescription medications.","label":0,"label_text":"Not-Related"}
+{"text":"Hepatotoxicity of hycanthone in patients with metastatic breast cancer.","label":1,"label_text":"Related"}
+{"text":"A 42-year-old woman was admitted to the hospital to receive intravenous acyclovir for a herpes zoster infection.","label":0,"label_text":"Not-Related"}
+{"text":"RATIONALE: The atypical antipsychotic clozapine is effective in the treatment of patients with refractory schizophrenia.","label":0,"label_text":"Not-Related"}
+{"text":"In this case report, osteonecrosis of the maxilla in a 48-year-old female patient who was treated for acute myelogenous leukemia is presented.","label":0,"label_text":"Not-Related"}
+{"text":"Enoxaparin is the current anticoagulant of choice with advantages for the treatment of neonatal thrombosis.","label":0,"label_text":"Not-Related"}
+{"text":"Postoperatively, the first two patients treated with 1 to 2 cc of thrombin were slow to awaken; one had evidence of vasospasm by transcranial Doppler ultrasound studies and multiple infarcts on cranial computerized tomography, while the other had a moderate-sized frontal hematoma with intracranial hypertension.","label":1,"label_text":"Related"}
+{"text":"We report a case of a 74-year-old man with chronic lymphocytic leukemia who received high-dose intermittent chlorambucil and prednisone every two weeks.","label":0,"label_text":"Not-Related"}
+{"text":"Serial physiologic and echocardiographic parameters were followed.","label":0,"label_text":"Not-Related"}
+{"text":"However, in spite of the early successful treatment with dantrolene the MH reaction recurred 12 h after the initial symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"Nevertheless, overdosage and intoxication are well documented.","label":0,"label_text":"Not-Related"}
+{"text":"These observations suggest that G-CSF\/Ara-C therapy may be useful in the treatment of high-risk AML.","label":0,"label_text":"Not-Related"}
+{"text":"Methotrexate (MTX) is a commonly used second line agent for RA, and there have been several recent reports of Epstein-Barr virus (EBV)-associated polyclonal B cell lymphoproliferative disorder in MTX-treated RA patients.","label":1,"label_text":"Related"}
+{"text":"Methylene blue in the treatment and prevention of ifosfamide-induced encephalopathy: report of 12 cases and a review of the literature.","label":1,"label_text":"Related"}
+{"text":"The shunt infection was controlled by removal of the shunt and a combination of systemic and intraventricular administration of amikacin, and oral administration of ofloxacin.","label":0,"label_text":"Not-Related"}
+{"text":"Transient phenytoin induced IgA deficiency and permanent IgE increase.","label":1,"label_text":"Related"}
+{"text":"We report a patient with multiple myeloma who suffered from hyperammonemia after a second stem cell autograft.","label":0,"label_text":"Not-Related"}
+{"text":"Early bacterial keratitis after laser-assisted subepithelial keratectomy.","label":0,"label_text":"Not-Related"}
+{"text":"In this report, two cases of ET which evolved into AL without prior exposure to radiation or alkylating agents, and which were treated with long-term hydroxyurea therapy, are described.","label":1,"label_text":"Related"}
+{"text":"We report a case of severe hyperphosphatemia resulting in transient acute renal failure corrected rapidly by hemodialysis.","label":0,"label_text":"Not-Related"}
+{"text":"In addition, she had a central scotoma (RE > LE) on automated visual field analysis (Humphrey central 30 degrees ).","label":0,"label_text":"Not-Related"}
+{"text":"Lipoid pneumonia: a silent complication of mineral oil aspiration.","label":1,"label_text":"Related"}
+{"text":"We also report, for comparison, a patient treated with conventional AmB, and preliminary studies in mice comparing the two agents.","label":0,"label_text":"Not-Related"}
+{"text":"The other woman had rheumatoid arthritis and developed acute tubular necrosis after treatment with gentamicin and cefoxitin.","label":1,"label_text":"Related"}
+{"text":"Mycobacterium interface keratitis after laser in situ keratomileusis.","label":0,"label_text":"Not-Related"}
+{"text":"Although adverse sequelae to these episodes of hypertension were not noticed, this report documents the uptake of phenylephrine from topical ocular application and suggests the need for dose-response measurements for this adjunct to mydriatic treatment in dogs.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Hypersensitivity reactions to cyclosporine are due to Cremophor EL.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND: Gemcitabine has mild renal toxicity, but cases of gemcitabine-associated hemolytic-uremic syndrome (HUS) have been reported.","label":1,"label_text":"Related"}
+{"text":"The clinical features and different drug-induced movement scales showed an outstanding improvement after tetrabenazine was started.","label":0,"label_text":"Not-Related"}
+{"text":"All patients presented with sudden painless dimness of vision with photophobia.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: We describe the ophthalmic features and clinical course of two cases of acute syphilitic posterior placoid chorioretinitis (ASPPC) that developed after intravitreal triamcinolone acetonide (IVTA) injection.","label":1,"label_text":"Related"}
+{"text":"Report of two cases.","label":0,"label_text":"Not-Related"}
+{"text":"The patient had leukocytosis with a large percentage of atypical lymphocytes on peripheral smear and liver dysfunction.","label":0,"label_text":"Not-Related"}
+{"text":"In a female with acute lymphoblastic leukemia, inadvertent doxorubicin administration intrathecally caused severe, life-threatening, acute encephalopathy with high-pressure hydrocephalus.","label":1,"label_text":"Related"}
+{"text":"We describe a patient who, after receiving his first dose of pregabalin to relieve neuropathic pain, presented with a negative myoclonus.","label":1,"label_text":"Related"}
+{"text":"This report describes a case of flucytosine-associated ulcerating enteritis in which the small bowel x-ray demonstrated severe luminal narrowing, ulceration, and marked separation of loops of bowel.","label":1,"label_text":"Related"}
+{"text":"Additionally, danazol produces hepatocellular damage in approximately 10% of women.","label":1,"label_text":"Related"}
+{"text":"Treatment with CSA was started after a nonresponding course of prednisone.","label":0,"label_text":"Not-Related"}
+{"text":"A patient with seropositive rheumatoid arthritis developed ascites while taking weekly doses of methotrexate (MTX).","label":1,"label_text":"Related"}
+{"text":"Chemotherapy-related hemolytic-uremic syndrome after the treatment of head and neck cancer.","label":0,"label_text":"Not-Related"}
+{"text":"The treatment of FMF attacks in patients who cannot use colchicine is an important problem.","label":0,"label_text":"Not-Related"}
+{"text":"Serious phenytoin hypersensitivity reactions may appear as dermatologic, lymphoid, or hepatic syndromes.","label":1,"label_text":"Related"}
+{"text":"The authors report two cases of catechol-O-methyltransferase (COMT) inhibitor-induced asymptomatic hepatic dysfunction in women with Parkinson disease.","label":0,"label_text":"Not-Related"}
+{"text":"Tetracycline-induced renal hypophosphatemia in a patient with a syndrome of inappropriate secretion of antidiuretic hormone.","label":0,"label_text":"Not-Related"}
+{"text":"CASE SUMMARY: A 6.1-year-old child received cyclosporine and methotrexate for acute graft-versus-host disease (aGVHD) prophylaxis after his first HSCT for acute myeloblastic leukemia.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was successfully managed with clopidogrel therapy during the 16 months follow-up without recurrent thrombotic or hemorrhagic events.","label":0,"label_text":"Not-Related"}
+{"text":"The success of the treatment was documented by the criterion of a return to the normal cardiorespiratory parameters a few hours after the start of the thrombolytic treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Both eyes became atrophied and had poor visual outcome: 10\/200 in one patient and no light perception in the other at 6 months after IVTA injection.","label":0,"label_text":"Not-Related"}
+{"text":"Agranulocytosis associated with ticlopidine: a possible benefit with filgastim.","label":1,"label_text":"Related"}
+{"text":"Prevention by mass media should mainly focus on the medical fatalities of abuse and not emphasize the hallucinogenic effects, presumably increasing unwanted interest for these plants among youths.","label":0,"label_text":"Not-Related"}
+{"text":"Trimethoprim-sulfamethoxazole-induced hepatotoxicity in a pediatric patient.","label":1,"label_text":"Related"}
+{"text":"Severe rhabdomyolysis following massive ingestion of oolong tea: caffeine intoxication with coexisting hyponatremia.","label":1,"label_text":"Related"}
+{"text":"The patient had seronegative (rheumatoid factor negative) poliarticular form of JRA and was receiving low dose weekly Methotrexate (MTX) during the past 2 years.","label":0,"label_text":"Not-Related"}
+{"text":"In this case senna was likely the cause of a subacute cholestatic hepatitis exemplifying again the potential role of herbal related liver injury.","label":1,"label_text":"Related"}
+{"text":"We report the case of a patient with chronic lymphocytic leukemia (CLL) who developed fatal intravascular autoimmune hemolytic anemia (AIHA) after fludarabine treatment.","label":1,"label_text":"Related"}
+{"text":"Two cases of bipolar affective disorder with tardive dystonic symptoms seemed to improve only with mood elevation, whether the latter occurred spontaneously or was 'induced' pharmacologically.","label":0,"label_text":"Not-Related"}
+{"text":"Renal biopsy of these children showed classical BMTN histology, and the renal manifestations progressed quickly; the patient in case 1 became dialysis dependent by 1 year post-bone marrow transplant.","label":0,"label_text":"Not-Related"}
+{"text":"Full recovery occurred because of early pick up, emphasizing the need for careful fluid balance monitoring of patients receiving cisplatin chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Ten months after the injection, visual acuity remained at 20\/50, and intraocular pressure measured 15 mm Hg without antiglaucomatous therapy taken.","label":0,"label_text":"Not-Related"}
+{"text":"Review of existing literature shows that in immunocompromised patients, GI cryptococcosis invariably coexists with disseminated cryptococcosis, often lacks prominent GI symptomatology, and is primarily diagnosed postmortem.","label":0,"label_text":"Not-Related"}
+{"text":"The literature search revealed 22 cases of hypersensitivity reaction to cyclosporine.","label":1,"label_text":"Related"}
+{"text":"Among atypical antipsychotic, clozapine, risperidone and olanzapine have been reported to be associated with the condition.","label":0,"label_text":"Not-Related"}
+{"text":"This report describes a case of flucytosine-associated ulcerating enteritis in which the small bowel x-ray demonstrated severe luminal narrowing, ulceration, and marked separation of loops of bowel.","label":1,"label_text":"Related"}
+{"text":"They received trihexyphenidyl with good results.","label":0,"label_text":"Not-Related"}
+{"text":"Her clinical course was complicated and the catecholamine and cortisol concentrations were still elevated 24 h after start of treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Clinical neurophysiological and neuroradiological findings and finally neuropathological studies in 2 patients resembled those found in vitamin-B12-deficiency-syndrome with a predominant affection of the spinal posterior column and the corticospinal tracts.","label":0,"label_text":"Not-Related"}
+{"text":"The phenotype overlaps with that of attention deficit disorder, raising the possibility of subtypes of attention deficit disorder that have a peripheral sensory cause and novel forms of therapy.","label":0,"label_text":"Not-Related"}
+{"text":"One major source of risk to patients is intraarterial or intraneural injections.","label":0,"label_text":"Not-Related"}
+{"text":"Bronchiolitis obliterans organising pneumonia associated with the use of nitrofurantoin.","label":1,"label_text":"Related"}
+{"text":"Administration of sumatriptan in subarachnoid haemorrhage (SAH) patients, misdiagnosed as migraine patients, may induce symptomatic cerebral vasospasm with potentially dangerous consequences.","label":1,"label_text":"Related"}
+{"text":"Until the mechanism of action responsible for fluid overload is known, we suggest that thiazolidinediones be administered with caution in all patients.","label":0,"label_text":"Not-Related"}
+{"text":"It is extremely resistant to standard treatment, and confers a poor prognosis for this disease.","label":0,"label_text":"Not-Related"}
+{"text":"Based on these findings and since the patient had no signs of infection, his physician instructed him to discontinue the drug.","label":0,"label_text":"Not-Related"}
+{"text":"Pulmonary hemorrhage is an uncommon feature in the HUS, and seems to appear especially in the HUS associated with MMC therapy.","label":1,"label_text":"Related"}
+{"text":"Many of the uncommon causes of CAPD peritonitis have been reviewed, with special emphasis on antimicrobial therapy and whether catheter removal was required.","label":0,"label_text":"Not-Related"}
+{"text":"This case indicates that C. indologenes infection can occur in diabetic children without ventilator or central venous catheter and might be treated with a single agent after in vitro susceptibility tests have been performed.","label":0,"label_text":"Not-Related"}
+{"text":"Approximately 15 min after the first administration of nebulised morphine the patient became markedly bradypneic (respiratory rate: 4-5 bpm), hypotensive (BP 70\/40 mmHg), and responded only partially to command.","label":1,"label_text":"Related"}
+{"text":"Thus, it is important for dermatologists treating patients with diabetes and antitumor necrosis factor-alpha agents for psoriasis to be aware of potential hypoglycemia and to adjust antidiabetes therapy accordingly.","label":0,"label_text":"Not-Related"}
+{"text":"No other drugs were detected.","label":0,"label_text":"Not-Related"}
+{"text":"Rapidly progressive glomerulonephritis during antituberculous therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Disopyramide (Norpace) is a recently released antiarrhythmic agent with quinidine-like actions, but structurally unique.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Both patients were negative for islet cell antibodies.","label":0,"label_text":"Not-Related"}
+{"text":"She had a history of diabetes and angina pectoris.","label":0,"label_text":"Not-Related"}
+{"text":"She recovered from the event without apparent chronic cardiac dysfunction.","label":0,"label_text":"Not-Related"}
+{"text":"Under constant mechanical ventilator settings, a highly significant linear correlation between peak airway pressure and arterial pCO(2)(r: 0.98 P<0.001) was observed.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: The use of ECT in patients with MG is a viable therapeutic option when psychiatric complications secondary to MG or its treatment do not respond to psychotropic medications.","label":0,"label_text":"Not-Related"}
+{"text":"The patient's symptoms were relieved with 0.5 mg intravenous atropine and she recovered uneventfully.","label":0,"label_text":"Not-Related"}
+{"text":"It appears that specific MEFV mutations are probably not the sole determinants of phenotype, and that unknown environmental factors or modifying genes act as accomplices in this disease.","label":0,"label_text":"Not-Related"}
+{"text":"PURPOSE: To evaluate the efficacy and safety of topical imiquimod 5% cream for the treatment of eyelid basal cell carcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"We speculated that SLE associated with systemic vasculitis and uremic milieu over a number of years may represent the perfect preexisting condition for calcific arteriolopathy to occur following which several factors including chronic administration of corticosteroids, photosensitivity in lupus, and significant weight loss may have contributed to acral gangrene and mesenteric ischemia.","label":0,"label_text":"Not-Related"}
+{"text":"A 43-year-old man presented suffering from decreasing vision in both eyes for 3 months.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of pediatric bupropion ingestion resulting in multiple seizures.","label":1,"label_text":"Related"}
+{"text":"Although the aetiology of their cerebral dysfunction can not be definitely ascertained this case series emphasizes the need for long-term prospective studies in patients with diabetes of long duration to assess the impact of the disorder on cognitive and social abilities particularly where there is evidence of cerebral dysfunction.","label":0,"label_text":"Not-Related"}
+{"text":"Clotrimazole is an antifungal agent that has been shown to have excellent in vitro activity against most strains of Acanthamoeba.","label":0,"label_text":"Not-Related"}
+{"text":"Three of the 36 patients were receiving aspirin for the treatment of juvenile rheumatoid arthritis.","label":0,"label_text":"Not-Related"}
+{"text":"A gradual spontaneous recovery of normal hematopoiesis followed after the lenalidomide discontinuation.","label":0,"label_text":"Not-Related"}
+{"text":"While doxorubicin was administered, the patient presented thoracic pain and breathing distress due to superior vena cava perforation by the central catheter and subsequent extravasation of the drug into the mediastinum.","label":1,"label_text":"Related"}
+{"text":"Hypersensitivity reactions to aromatic anticonvulsants are associated with anti-liver microsomal antibodies which recognise rodent proteins.","label":0,"label_text":"Not-Related"}
+{"text":"Three patients with a cellular immunodeficiency were treated with rifabutin, clarithromycin and ethambutol for a disseminated infection with Mycobacterium avium-intracellulare complex (MAC).","label":0,"label_text":"Not-Related"}
+{"text":"Fatal intoxication using amantadine and pramipexole in a uremic patient.","label":0,"label_text":"Not-Related"}
+{"text":"On the third occasion the patient redeveloped severe hypotension and a generalised rash during general anaesthesia.","label":0,"label_text":"Not-Related"}
+{"text":"All three patients were stabilized and their tachycardia was controlled with digoxin.","label":0,"label_text":"Not-Related"}
+{"text":"Hemodynamic collapse following labetalol administration in preeclampsia.","label":1,"label_text":"Related"}
+{"text":"Its radiosensitizing effect may be worth exploring at a lower dose level.","label":0,"label_text":"Not-Related"}
+{"text":"Despite cessation of daunomycin, she demonstrated fluctuating systolic function in relation to ATRA administration.","label":0,"label_text":"Not-Related"}
+{"text":"One year later, she has minimal joint discomfort and no rash or gastrointestinal symptoms despite also discontinuing prednisone and methotrexate.","label":0,"label_text":"Not-Related"}
+{"text":"Disseminated Nocardia infection has a high mortality and morbidity rate in solid organ transplant recipients, even when appropriate antibiotics are given.","label":0,"label_text":"Not-Related"}
+{"text":"Several different preparations are available including interferon beta 1a (Avonex, Rebif) and interferon beta 1b (Betaferon\/Betaseron).","label":0,"label_text":"Not-Related"}
+{"text":"However, re-initiation of sunitinib treatment was followed by bilateral breast enlargement again.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: We present a case of a patient with CML who developed KS 12 months after starting treatment with imatinib 400 mg\/d.","label":1,"label_text":"Related"}
+{"text":"We speculate that the beneficial effect of IFN-alpha in the treatment of PTLD is directly related to the inhibition of type 2 helper (Th2-like) T-cells.","label":0,"label_text":"Not-Related"}
+{"text":"If radiotherapy over extensive areas of the body is needed, the use of IL-2 must be postponed until radiotherapy is completed.","label":0,"label_text":"Not-Related"}
+{"text":"Dipyrone-induced granulocytopenia: a case for awareness.","label":1,"label_text":"Related"}
+{"text":"Although dacryocystography showed a dilated and partially obstructed nasolacrimal system, ultrasound examination was able to demonstrate a mass in the nasolacrimal duct.","label":0,"label_text":"Not-Related"}
+{"text":"These cases serve as a timely reminder of the importance of taking an accurate drug history in emergency situations.","label":0,"label_text":"Not-Related"}
+{"text":"Ibuprofen overdose is usually characterized by GI upset, dizziness, and mild sedation.","label":1,"label_text":"Related"}
+{"text":"Rifampicin-induced renal failure.","label":1,"label_text":"Related"}
+{"text":"Sagittal sinus thrombosis associated with transient free protein S deficiency after L-asparaginase treatment: case report and review of the literature.","label":1,"label_text":"Related"}
+{"text":"Fixed drug eruption to rofecoxib.","label":1,"label_text":"Related"}
+{"text":"Finally, it was decreased to 40 BU in the 36th week.","label":0,"label_text":"Not-Related"}
+{"text":"Riluzole is a new drug representing the first active treatment for amyotrophic lateral sclerosis.","label":0,"label_text":"Not-Related"}
+{"text":"These patients require not only treatment of their acute medical problems but also specialized multidisciplinary acute rehabilitation starting as early as possible during their hospital stay.","label":0,"label_text":"Not-Related"}
+{"text":"Anaphylactoid reaction to rattlesnake envenomation.","label":0,"label_text":"Not-Related"}
+{"text":"It is very likely that the dexamethasone used in the antiemetic drug regimen contributed to the development of osteonecrosis in these patients.","label":1,"label_text":"Related"}
+{"text":"A bubble in the inferior sagittal sinus was observed on the day of the stroke, which then disappeared within 24 hours.","label":0,"label_text":"Not-Related"}
+{"text":"Eight of the 14 women used no contraception at the time of the exposed pregnancy; 13 of the 14 women did not use two forms of contraception.","label":0,"label_text":"Not-Related"}
+{"text":"Pneumonitis with pleural and pericardial effusion and neuropathy during amiodarone therapy.","label":1,"label_text":"Related"}
+{"text":"This paper reviews the development of steroid therapy for spinal cord injuries, the mechanisms of action, and the nursing care associated with its use.","label":0,"label_text":"Not-Related"}
+{"text":"Subsequent investigation revealed that the factory produces phenylpropanolamine and that both patients, shortly before becoming ill, were inadvertently exposed to methyl nitrite, a critical reagent in this production.","label":0,"label_text":"Not-Related"}
+{"text":"An association of granulocytopenia, eosinophilia, skin reaction and hepatitis during propylthiouracil (PTU) therapy for thyrotoxicosis in a 47 year old black female is reported.","label":1,"label_text":"Related"}
+{"text":"Transient lymphomatoid papulosis in mycosis fungoides.","label":0,"label_text":"Not-Related"}
+{"text":"This latest (third) report suggests that the safety profile should be reexamined and at least raises the question of potential renal toxicity of interferons in MS.","label":1,"label_text":"Related"}
+{"text":"The interval between initiating treatment with interferon alfa and onset of anterior ischemic optic neuropathy was similar to that of interferon-associated vascular retinopathy.","label":1,"label_text":"Related"}
+{"text":"Using this test we diagnosed CMV infection in the fetus of a 30-year-old renal transplant recipient.","label":0,"label_text":"Not-Related"}
+{"text":"Pancytopenia is already present in GD patients and it is reasonable to expect an increased risk of hematological toxicity in treating solid tumors in these patients.","label":0,"label_text":"Not-Related"}
+{"text":"A 27-year-old man who had a history of bronchial asthma, eosinophilic enteritis, and eosinophilic pneumonia presented with fever, skin eruptions, cervical lymphadenopathy, hepatosplenomegaly, atypical lymphocytosis, and eosinophilia two weeks after receiving trimethoprim (TMP)-sulfamethoxazole (SMX) treatment.","label":1,"label_text":"Related"}
+{"text":"Malignant myelosclerosis or acute myelofibrosis is a rare acute myeloproliferative disorder characterized by pancytopenia, myeloblastosis and marrow fibrosis.","label":0,"label_text":"Not-Related"}
+{"text":"In light of the widespread use of bleomycin, this complication may be under-appreciated.","label":0,"label_text":"Not-Related"}
+{"text":"Initially, this reaction was thought to be a result of a drug allergy, but upon further review, we determined that it was JHR.","label":0,"label_text":"Not-Related"}
+{"text":"Priapism is a rare but serious adverse effect of psychotropic drugs where antipsychotic agents were implicated in 15 to 26% of priapism associated with medications.","label":0,"label_text":"Not-Related"}
+{"text":"We suggest that the duration of chemotherapy required to achieve a cure in patients with ovarian carcinoma in complete remission can be determined only by prospective controlled trials.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of a previously healthy, postmenopausal woman who developed anticonvulsant hypersensitivity syndrome while taking Bellamine S (belladonna alkaloids; ergotamine; phenobarbital) for hot flashes.","label":1,"label_text":"Related"}
+{"text":"However, data published since acyclovir became available do not indicate increased adverse effects related to its use in pregnancy, especially if prescribed in selected situations, such as disseminated primary herpes simplex infections or maternal varicella pneumonia.","label":0,"label_text":"Not-Related"}
+{"text":"Double jeopardy?","label":0,"label_text":"Not-Related"}
+{"text":"Recently, RA has been added to the post-BMT therapy in children with stage IV neuroblastoma.","label":0,"label_text":"Not-Related"}
+{"text":"The association of systemic inflammatory disorders with osteonecrosis and the possible association with vascular thrombosis are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"The principle treatment for DPD-deficient patients with severe acute 5-FU reactions is supportive care; however, the administration of thymidine potentially may reverse severe 5-FU-induced neurologic symptoms such as encephalopathy and coma.","label":1,"label_text":"Related"}
+{"text":"Along with receiving multiple other drugs, the patient was started on a continuous i.v. infusion of dobutamine 3 mug\/kg\/min.","label":0,"label_text":"Not-Related"}
+{"text":"In all patients, oral prednisolone (PSL) alternative day therapy was attempted and three patients responded very well (complete remission 2, partial remission 1).","label":0,"label_text":"Not-Related"}
+{"text":"Chylous ascites, a rare compliation following retroperitoneal lymph node dissection, has not been reported as a means of spread of testicular cancer.","label":0,"label_text":"Not-Related"}
+{"text":"We report 2 cases of AIT: in one case, amiodarone was interrupted; in the other case, amiodarone was continued because of recurrent ventricular tachycardia resistant to classical antiarrhythmic drugs.","label":0,"label_text":"Not-Related"}
+{"text":"Hyponatremic seizures after suprapubic catheter placement in 7-year-old child.","label":0,"label_text":"Not-Related"}
+{"text":"Such anagen effluvium with lichenoid eruption following INH therapy has not been observed previously.","label":1,"label_text":"Related"}
+{"text":"CASE DESCRIPTION: A 37-year-old woman was started on weekly interferon beta-1a (IFN beta-1a) following a diagnosis of multiple sclerosis (MS).","label":0,"label_text":"Not-Related"}
+{"text":"Although the true frequency of adverse fetal effects has yet to be determined, because of the debilitating and lethal nature of the fetal damage when it occurs, it is our recommendation that ACE inhibitors not be used in pregnancy, particularly in the second and third trimesters.","label":0,"label_text":"Not-Related"}
+{"text":"He had been treated with oral cyclophosphamide for 13 years.","label":0,"label_text":"Not-Related"}
+{"text":"FK506 dose level was maintained and then reduced.","label":0,"label_text":"Not-Related"}
+{"text":"This paper outlines the indications and precautions for use and side effects of monoamine oxidase inhibitors in the treatment of depression in elderly patients.","label":0,"label_text":"Not-Related"}
+{"text":"A 64-year-old man with schizophrenia developed myoclonic jerks when given higher doses of quetiapine.","label":1,"label_text":"Related"}
+{"text":"A 10-year-old boy with osteosarcoma and normal renal function manifested laboratory evidence of impending renal toxicity and extreme elevation of aspartate aminotrasferase and alanine aminotransferase within 2 hours after the completion of a 4-hour infusion of high-dose methotrexate (MTX) (12 g\/m2), and went on to develop acute renal failure with life-threatening hyperkalemia 29 hours later.","label":1,"label_text":"Related"}
+{"text":"Thus this patient's hyponatremia cannot be accounted for solely by changes in external water and electrolyte balance; the rapidity with which changes were produced suggests that osmolar inactivation, probably intracellularly, may contribute to the severe hypotonicity seen in some patients.","label":0,"label_text":"Not-Related"}
+{"text":"Visual hallucinations associated with zonisamide.","label":1,"label_text":"Related"}
+{"text":"One RA patient and one AA patient have received rEpo as maintenance therapy for more than 64 and 100 weeks, respectively.","label":0,"label_text":"Not-Related"}
+{"text":"The presence of inappropriate sexual behaviors in individuals with autistic disorder is one of the important factors disturbing their social adaptation and distressing their families and environment.","label":0,"label_text":"Not-Related"}
+{"text":"The conditions treated were: Hodgkin's disease (four patients), primary amyloidosis, primary macroglobulinemia, malignant lymphoma, multiple myeloma, and carcinoma of the tonsil.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: This patient's rhabdomyolysis was probably induced by sertraline therapy.","label":1,"label_text":"Related"}
+{"text":"Usefulness of antiplatelet drugs in the management of heparin-associated thrombocytopenia and thrombosis.","label":1,"label_text":"Related"}
+{"text":"Multifocal disseminated lipoatrophy secondary to intravenous corticosteroid administration in a patient with adrenal insufficiency.","label":0,"label_text":"Not-Related"}
+{"text":"Tumors were assessed for immunohistochemical evidence of mTORC1 activation and genetic evidence of alterations in TSC1 and TSC2.","label":0,"label_text":"Not-Related"}
+{"text":"On hospital admission, blood pressure of the intubated, bradyarrhythmic patient was 100\/65 mmHg.","label":0,"label_text":"Not-Related"}
+{"text":"Visual field improvement after neodymium: YAG laser puncture of miotic cysts.","label":0,"label_text":"Not-Related"}
+{"text":"The mutants K122R, F134L and G145A in our patient have not been tested for their sensitivity to Architect and Murex assays by the previous investigators and might represent the escape mutants to these assays.","label":0,"label_text":"Not-Related"}
+{"text":"The case demonstrates that hypersensitivity reaction to pranlukast and resultant ATIN is possible, and that periodic urine testing in patients receiving pranlukast should be considered.","label":1,"label_text":"Related"}
+{"text":"Growth hormone deficiency after localized ganglioneuroblastoma: A case report.","label":0,"label_text":"Not-Related"}
+{"text":"N-acetylcysteine and Unverricht-Lundborg disease: variable response and possible side effects.","label":0,"label_text":"Not-Related"}
+{"text":"We present the case of a 58-year-old woman who ingested more than 35 g of caffeine in a suicide attempt.","label":1,"label_text":"Related"}
+{"text":"Clinical toxicity of reserpine in hospitalized patients: a report from the Boston Collaborative Drug Surveillance Program.","label":0,"label_text":"Not-Related"}
+{"text":"Caution in longterm usage and early recognition of pentazocine toxicity as a neuromuscular complication are important in order to prevent irreversible drug-induced fibrous myopathy and localized neuropathy.","label":1,"label_text":"Related"}
+{"text":"We ultimately speculated that corticosteroid withdrawal induced the depressive symptoms in this case.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: Anastrozole is a selective aromatase inhibitor and is used for the hormonal treatment of postmenopausal breast cancer.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: One patient progressed to chronic renal failure and required prolonged dialysis followed by renal transplantation, though the leukemia remained in remission.","label":0,"label_text":"Not-Related"}
+{"text":"The wound and tissue cultures were negative.","label":0,"label_text":"Not-Related"}
+{"text":"Blood biochemistry revealed severe liver dysfunction, although no markers including hepatitis virus or autoantibodies associated with autoimmune liver diseases were detected.","label":0,"label_text":"Not-Related"}
+{"text":"The use of antithymocyte globulin in the treatment of severe aplastic anemia in children.","label":0,"label_text":"Not-Related"}
+{"text":"The response to clozapine appears to be specific and relapses occurred when maintenance medication was stopped.","label":0,"label_text":"Not-Related"}
+{"text":"A patient with chronic myeloid leukaemia treated with busulphan for 4-5 years, developed signs of busulphan toxicity and portal hypertension with ascites, oesophageal varices and jaundice.","label":1,"label_text":"Related"}
+{"text":"Olanzapine-induced hyperglycaemic coma and neuroleptic malignant syndrome: case report and review of literature.","label":1,"label_text":"Related"}
+{"text":"Uncontrolled headache induced by oxcarbazepine.","label":1,"label_text":"Related"}
+{"text":"Parenteral challenge with suspected sensitizing agents confirmed methicillin as the likely offender.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of an 87-year-old white woman with myasthenia gravis who presented with nausea, shortness of breath, azotemia, and hyperkalemia shortly after completing a course of intravenous immunoglobulin (IVIG).","label":1,"label_text":"Related"}
+{"text":"Captopril is an angiotensin-converting enzyme (ACE) inhibitor and their cutaneous side-effects are documented, but little has been published concerning the usefulness of patch test when they occur.","label":1,"label_text":"Related"}
+{"text":"Cutaneous infection is rare and about 71 cases have been described, mainly in Europe in immunocompromised hosts.","label":0,"label_text":"Not-Related"}
+{"text":"Use of leflunomide in an allogeneic bone marrow transplant recipient with refractory cytomegalovirus infection.","label":0,"label_text":"Not-Related"}
+{"text":"IMPLICATIONS: Switching from bupivacaine to lidocaine may improve intrathecal morphine analgesia in advanced cancer patients, possibly because of different spinal mechanisms limiting the hyperalgesic processes.","label":0,"label_text":"Not-Related"}
+{"text":"DISCUSSION: The Naranjo probability scale indicates C. mukul as the possible cause of rhabdomyolysis in our patient.","label":0,"label_text":"Not-Related"}
+{"text":"The participants all reported heightened sensitivity to one or several odors which could not fully be explained by the potential explanatory models of anticipatory nausea and vomiting, pseudohallucinations, or increased chemical sensitivity.","label":0,"label_text":"Not-Related"}
+{"text":"Transient phenytoin induced IgA deficiency and permanent IgE increase.","label":1,"label_text":"Related"}
+{"text":"She had received subcutaneous heparin as prophylaxis for deep vein thrombosis during a 5-day hospitalization for postpartum cardiomyopathy.","label":0,"label_text":"Not-Related"}
+{"text":"Even after a strict warning, he took another quinine tablet that evening, which triggered his fifth episode of severe thrombocytopenia, and confirmed the etiology of quinine-induced thrombocytopenia.","label":1,"label_text":"Related"}
+{"text":"The routine immunologic studies were normal.","label":0,"label_text":"Not-Related"}
+{"text":"Unique to this case, however, was the substitution of another angiotensin-converting enzyme inhibitor, enalapril, without exacerbation of the pemphigus.","label":0,"label_text":"Not-Related"}
+{"text":"Venlafaxine blocks the specific monoamine transporters and is devoid of significant action on muscarinic cholinergic receptors.","label":0,"label_text":"Not-Related"}
+{"text":"The authors describe two patients with this disease who initially had findings suggestive of an optic neuropathy.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Itraconazole-induced liver injury presents with a cholestatic pattern of injury with damage to the interlobular bile ducts, possibly leading to ductopenia.","label":1,"label_text":"Related"}
+{"text":"Here we report a case of R. equi-associated pulmonary abscess in a renal transplant recipient successfully treated with a combination of carbapenem and teicoplanin.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of restenosis after bare-metal and drug-eluting stenting of an aorto-ostial lesion: challenges associated with excessive stent overhang.","label":0,"label_text":"Not-Related"}
+{"text":"Intravenous warfarin as an alternative for anticoagulation.","label":0,"label_text":"Not-Related"}
+{"text":"Aggressive combination chemotherapy was required to reverse progressive thrombocytopenia and pulmonary involvement.","label":0,"label_text":"Not-Related"}
+{"text":"This treatment resulted in remission of the vasculitis.","label":0,"label_text":"Not-Related"}
+{"text":"We have shown that CMV-polymerase chain reaction of AF is a useful diagnostic test for congenital CMV infection.","label":0,"label_text":"Not-Related"}
+{"text":"In four of the five patients, right-sided focal seizures were subsequently noted.","label":0,"label_text":"Not-Related"}
+{"text":"The proportions of lymphocyte subsets, as defined with monoclonal antibodies, and the proliferative response to mitogens were normal.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Vitritis occurred in 8 patients (12 episodes), 2 to 23 months postoperatively.","label":0,"label_text":"Not-Related"}
+{"text":"Our objective is to present a retrospective analysis of the DWI findings in four patients who suffered subacute neurotoxicity after intrathecal MTX.","label":1,"label_text":"Related"}
+{"text":"On rechallenging the patient with the drug following the implantation of a permanent pacemaker, intermittent complete heart block developed.","label":0,"label_text":"Not-Related"}
+{"text":"Only one case of severe symptomatic hepatitis occurring after pulse therapy with itraconazole for onychomycosis and requiring transplantation has been reported previously.","label":1,"label_text":"Related"}
+{"text":"Our report lends further support to the assumption that COX-2 inhibitors, as a class, can be as nephrotoxic as their nonselective predecessors.","label":0,"label_text":"Not-Related"}
+{"text":"Squamous-cell carcinoma arising in a basal-cell epithelioma treated with 5-fluorouracil.","label":1,"label_text":"Related"}
+{"text":"A young woman with epilepsy had tonic-clonic seizures during antineoplastic therapy with adriamycin and cisplatin.","label":1,"label_text":"Related"}
+{"text":"Acute vision loss after intravitreal injection of bevacizumab (avastin) associated with ocular ischemic syndrome.","label":1,"label_text":"Related"}
+{"text":"Other NSAIDs of the propionic acid family can also cause pseudoporphyria.","label":0,"label_text":"Not-Related"}
+{"text":"In this article lithium is not discussed, although there are a number of concerns about lithium's potential teratogenicity, and it has been implicated in Epstein's anomaly, a congenital heart defect among infants born to women taking lithium; as with other medications, however, the data have specific limitations.","label":1,"label_text":"Related"}
+{"text":"Collagenous colitis as a subtype of microscopic colitis is a rare cause of chronic diarrhea with unknown pathogenesis.","label":0,"label_text":"Not-Related"}
+{"text":"We conclude that symptoms of a postdural puncture headache can mimic those of postpartum preeclampsia.","label":0,"label_text":"Not-Related"}
+{"text":"Despite the known pulmonary side effects of nitrofurantoin, there is no report of this toxicity occurring in pregnant patients.","label":1,"label_text":"Related"}
+{"text":"There is no study on the incidence rate among children with systemic malignancies.","label":0,"label_text":"Not-Related"}
+{"text":"Both patients made an uneventful recovery.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment with aripiprazole resulted in a reduction in the frequency, duration, and severity of episodes of alternating hemiplegia, along with other therapeutic benefits.","label":0,"label_text":"Not-Related"}
+{"text":"Conservative follow-up after epidural abscess and diskitis complicating instrumented metal interbody cage.","label":0,"label_text":"Not-Related"}
+{"text":"Thrombo-embolic complication after streptokinase therapy of pulmonary emboli.","label":1,"label_text":"Related"}
+{"text":"While peripheral neuropathy and cranial nerve involvement is common, optic neuropathy is extremely rare.","label":0,"label_text":"Not-Related"}
+{"text":"A 22-year-old black man developed fever, chills, fatigue, night sweats, tender lymphadenopathy, and a generalized, pruritic, macular eruption 3 weeks after starting minocycline therapy for acne.","label":1,"label_text":"Related"}
+{"text":"On day 7 of linezolid treatment, the patient developed severe pruritus, macular rash, facial edema, eosinophilia, marked increase in serum creatinine level, and mild hepatitis.","label":1,"label_text":"Related"}
+{"text":"CASE PRESENTATION: A 52-year-old-male was administered chemotherapy with oxaliplatin, 5-fluorouracil and leucovorin for a Duke's stage C colorectal carcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"Finally, the patient entered complete hematological and cytogenetic remission, although the PML-RAR alpha fusion product was still detectable by PCR.","label":0,"label_text":"Not-Related"}
+{"text":"She developed dark-red coloration on her hands, at the fourth day of treatment, which has been defined as fixed drug eruption.","label":0,"label_text":"Not-Related"}
+{"text":"The reported cases of in utero exposure to cyclosposphamide shared the following manifestations with our patient: growth deficiency, developmental delay, craniosynostosis, blepharophimosis, flat nasal bridge, abnormal ears, and distal limb defects including hypoplastic thumbs and oligodactyly.","label":1,"label_text":"Related"}
+{"text":"Precautionary measures for the early recognition of this grave hazard in exposed patients are advocated.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To describe two cases of rhabdomyolysis in patients taking lovastatin that were precipitated by the use of the newer macrolide antibiotics clarithromycin and azithromycin.","label":1,"label_text":"Related"}
+{"text":"A 36-year-old patient with HIV developed a set of progressive left hemiparesis and secondarily generalized partial seizures related to progressive multifocal leukoencephalopathy.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was extubated 24 h after her arrival to the ICU and discharged 72 h later.","label":0,"label_text":"Not-Related"}
+{"text":"Despite intensive hemodialysis and other supportive therapy, he developed multiple organ failure (liver, renal, and respiratory failure) and metabolic acidosis.","label":0,"label_text":"Not-Related"}
+{"text":"However, in addition to its antiviral activity, IFN is a pleiotropic cytokine able to synergistically amplify T-cell autoreactivity.","label":0,"label_text":"Not-Related"}
+{"text":"This case history, however, illustrates the susceptibility to these agents shown by some patients.","label":0,"label_text":"Not-Related"}
+{"text":"Similar to reports in patients receiving gefitinib, those with pathologic findings of UIP on resected lung specimens or known pulmonary fibrosis may be at particular risk for erlotinib pulmonary toxicity.","label":1,"label_text":"Related"}
+{"text":"Fifteen months after surgical resection and adjuvant chemotherapy, the donor had no evidence of recurrent tumor.","label":0,"label_text":"Not-Related"}
+{"text":"After 1 week of nefazodone therapy the patient experienced headache, confusion, and \"gray areas\" in her vision, without abnormal ophthalmologic findings.","label":1,"label_text":"Related"}
+{"text":"Anaphylactoid reaction to 50% solution of dextrose.","label":1,"label_text":"Related"}
+{"text":"The rapid development of pulmonary aspergillosis associated with the formation of an Aspergillus mycetoma should be attributed to the loss of normal immune mechanisms due to immunosuppressive treatment.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Colchicine has a known adverse effect on wound healing through its inhibitory effect on tubulin-dependent cell functions and through collagenase activation.","label":1,"label_text":"Related"}
+{"text":"FINDINGS: During this 3-year period, the Netherlands Pharmacovigilance Centre Lareb received 2522 reports directly from patients, concerning 5401 ADRs.","label":0,"label_text":"Not-Related"}
+{"text":"Among the serious systemic complications encountered were three instances of respiratory arrest and one of cardiorespiratory arrest.","label":0,"label_text":"Not-Related"}
+{"text":"[2] Anesthetized and intubated ferrets inhaled a placebo or VVR that was placed at the proximal end of the endotracheal tube.","label":0,"label_text":"Not-Related"}
+{"text":"Three patients with no history of asthma or allergy developed bronchospasm while taking propranolol for hypertension.","label":1,"label_text":"Related"}
+{"text":"Topical provocation with ceftriaxone sodium salt (1% in water [aq.], 5% aq., 10% in petrolatum [pet.], 20% pet.) remained negative both at previously affected sites and in the unaffected skin of the back.","label":0,"label_text":"Not-Related"}
+{"text":"Most adverse events are due to an infusion-related symptom complex, and severe pulmonary complications are rare.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment with isoniazid and ethambutol led to total recovery from pulmonary tuberculosis.","label":0,"label_text":"Not-Related"}
+{"text":"She subsequently had penetrating keratoplasty and lens extraction with IOL implantation in the right eye.","label":0,"label_text":"Not-Related"}
+{"text":"After abstinence from oolong tea his delirium resolved.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: A patient with CHF and ESRD developed myoclonic muscle spasms after receiving dobutamine by continuous i.v. infusion.","label":1,"label_text":"Related"}
+{"text":"In case 1, a total daily dose of 25 mg sertraline, with nondetectable sertraline and desmethylsertraline blood levels, resulted in a doubling of the lamotrigine blood level with symptoms of toxicity.","label":1,"label_text":"Related"}
+{"text":"Although this patient had been exposed to several other medications more commonly associated with TEN, his long-term tolerance of and uneventful rechallenge with these medications exclude them as potential catalysts to this drug reaction.","label":0,"label_text":"Not-Related"}
+{"text":"Malignant gliomas encompassing the eloquent areas cannot be removed totally and their surgical extirpation is followed by adjuvant therapy for the residual tumor.","label":0,"label_text":"Not-Related"}
+{"text":"This case reinforces the importance of considering infectious complications, such as those from endemic mycoses, in patients receiving treatment with a TNF-alpha antagonist and the importance of having a well-designed monitoring plan when subjects in a research study become ill.","label":0,"label_text":"Not-Related"}
+{"text":"Both children were treated with antibiotics and steroids.","label":0,"label_text":"Not-Related"}
+{"text":"The possibility that thiocyanate level in a newborn is unreliable as indicator of sodium nitroprusside overdosage is considered.","label":0,"label_text":"Not-Related"}
+{"text":"Thereafter LMWH was discontinued.","label":0,"label_text":"Not-Related"}
+{"text":"The five cases reported so far are reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"Remission of psoriasis after treatment with interferon-alfa and 2-chlordeoxyadenosine for hairy cell leukemia.","label":0,"label_text":"Not-Related"}
+{"text":"Drug-induced hepatitis in an acromegalic patient during combined treatment with pegvisomant and octreotide long-acting repeatable attributed to the use of pegvisomant.","label":1,"label_text":"Related"}
+{"text":"CASE SUMMARY: A 66-year-old white woman with a 10-year history of hypertension and bronchial asthma was switched from immediate-release verapamil hydrocloride 40 mg tid to sustained-release verapamil 240 mg\/d po for better hypertension control.","label":0,"label_text":"Not-Related"}
+{"text":"CASES: Sonograms were done within 24 hours after administration of thrombolytic agents at 15 and 26 weeks of gestation, respectively, in 2 women whose pregnancies were complicated with thrombosis of prosthetic mitral valves.","label":0,"label_text":"Not-Related"}
+{"text":"Serum myoglobin was over 3000 ng\/mL.","label":0,"label_text":"Not-Related"}
+{"text":"He had been taking trimethoprim-sulfamethoxazole for approximately eight days when he revisited his family physician, complaining of headaches, dizziness, difficulty with speech, weakness, and itching on the trunk of his body and legs, where a maculopapular rash was noted.","label":1,"label_text":"Related"}
+{"text":"The possibility of phenytoin hypersensitivity reactions should be considered when patients receiving phenytoin have unusual symptoms, particularly fever, rash, and lymphadenopathy.","label":1,"label_text":"Related"}
+{"text":"Therefore, we gradually reduced the opiate dosage.","label":0,"label_text":"Not-Related"}
+{"text":"To our knowledge, no case of fatal agranulocytosis as a result of olanzapine treatment was reported in the literature.","label":0,"label_text":"Not-Related"}
+{"text":"Both patients developed a severe, sustained hypothyroidism requiring thyroxine treatment for one year or more after stopping alpha interferon.","label":0,"label_text":"Not-Related"}
+{"text":"B-CLL patients treated with fludarabine appear to be at risk for TA-GVHD and should be regarded as candidates for transfusions with irradiated blood products.","label":0,"label_text":"Not-Related"}
+{"text":"In patient 2, thrombolysis caused mobilisation of thrombotic mass as evidenced by disappearance of thrombus on ultrasound.","label":0,"label_text":"Not-Related"}
+{"text":"Pulmonary fibrosis is a complication of paclitaxel therapy that may occur despite treatments with corticosteroids.","label":1,"label_text":"Related"}
+{"text":"After these were corrected the amphotericin B was restarted and the course of treatment completed successfully.","label":0,"label_text":"Not-Related"}
+{"text":"Soon after the third weekly session of the second protocol, the clinical status of the animal deteriorated suddenly and severely, with a bleeding tendency, jaundice, hyperuricaemia, hyperphosphataemia, azotaemia, hyperbilirubinaemia and, presumptive disseminated intravascular coagulation.","label":0,"label_text":"Not-Related"}
+{"text":"Both the psoriasis and the HCL cleared.","label":0,"label_text":"Not-Related"}
+{"text":"Estimated daily intake of propranolol in breast milk by the infant was about 3 micrograms.","label":0,"label_text":"Not-Related"}
+{"text":"His serum carbamazepine concentration was 3.9 microg\/mL (reference range, 4-12 microg\/mL), and his serum ammonia concentration was 127 microg\/dL (reference range, 19-60 microg\/dL).","label":0,"label_text":"Not-Related"}
+{"text":"His blood sugar became uncontrolled, he gained 13 pounds, and his A1c increased to 9.4%.","label":0,"label_text":"Not-Related"}
+{"text":"In each of the five patients, adenosine was given in a standard fashion (6 or 12 mg).","label":0,"label_text":"Not-Related"}
+{"text":"Contact dermatitis due to budesonide: report of five cases and review of the Japanese literature.","label":1,"label_text":"Related"}
+{"text":"Blood cultures from the patient and from the plateletpheresis component were both positive for the presence of Streptococcus agalactiae.","label":0,"label_text":"Not-Related"}
+{"text":"Our patient had headache, mild fever, nausea, vomiting, rash, and eosinophilia after 3 weeks of disulfiram therapy.","label":1,"label_text":"Related"}
+{"text":"Behavioral side effects associated with clonazepam may include agitation, aggression, hyperactivity, irritability, property destruction, and temper tantrums.","label":1,"label_text":"Related"}
+{"text":"The 2 children were discharged on days 13 and 16 and cytostatic therapy was restarted on days 18 and 25.","label":0,"label_text":"Not-Related"}
+{"text":"Although major hazards of treatment of hypophosphatemic osteomalacia with phosphate and calcitriol are secondary hyperparathyroidism and vitamin D intoxication, potassium loss also should be kept in mind.","label":1,"label_text":"Related"}
+{"text":"Second malignant neoplasm in childhood is increasing due to advances in therapy modalities.","label":0,"label_text":"Not-Related"}
+{"text":"In addition, he was given a continuous infusion of 400 micrograms daily human recombinant granulocyte macrophage-colony stimulating factor (rh GM-CSF) for 17 days.","label":0,"label_text":"Not-Related"}
+{"text":"Although given ephedrine, epinephrine, and atropine sulfate, the patient's normal heart rhythm could not be restored until calcium chloride was administered.","label":0,"label_text":"Not-Related"}
+{"text":"Unpredictable and potentially life-threatening, immune thrombocytopenia can occur with any drug, at times even after long, uneventful use.","label":0,"label_text":"Not-Related"}
+{"text":"In case #3, the concentrations of quetiapine found in femoral blood was 5.90 mg\/L (15 micromol\/L).","label":0,"label_text":"Not-Related"}
+{"text":"The current case demonstrates that some cystoid macular edema may not be responsive to vascular endothelial growth factor blockade alone.","label":0,"label_text":"Not-Related"}
+{"text":"Acute dystonia induced by lamivudine.","label":1,"label_text":"Related"}
+{"text":"OBJECTIVE: To report three cases of bilateral Acanthamoeba keratitis in association with Synergeyes hybrid contact lens wear.","label":0,"label_text":"Not-Related"}
+{"text":"These two cases highlight the importance of considering lopinavir\/ritonavir induced arrhythmias when dealing with HIV-positive individuals.","label":1,"label_text":"Related"}
+{"text":"Carboplatin hypersensitivity induced by low-dose paclitaxel\/carboplatin in multiple platinum-treated patients with recurrent ovarian cancer.","label":1,"label_text":"Related"}
+{"text":"Magnetic resonance imaging (MRI) showed lesions suggestive of PRES.","label":0,"label_text":"Not-Related"}
+{"text":"Unfortunately, the patient died from adult respiratory distress syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Paralytic ileus in patients undergoing bortezomib treatment has been reported, although a definite attribution to bortezomib administration has not been established.","label":1,"label_text":"Related"}
+{"text":"Microscopic sections from a biopsy at 12 h revealed epidermal necrosis, superficial ulceration, and a mild superficial and deep perivascular lymphoid infiltrate, associated with numerous thrombi of small vessels throughout the dermis.","label":0,"label_text":"Not-Related"}
+{"text":"Antidepressive treatment with fluoxetine 20 mg daily was initiated which was successful.","label":0,"label_text":"Not-Related"}
+{"text":"Though the acute complications of lithium toxicity involving the central nervous system have been known for more than 70 years, it is only recently that the longlasting sequelae of lithium intoxication have come to be discussed at length; about fifty-five cases have been reported so far.","label":0,"label_text":"Not-Related"}
+{"text":"Epithelioid angiosarcoma of the lung is a rare late complication of Lucite plombage treatment of pulmonary tuberculosis.","label":0,"label_text":"Not-Related"}
+{"text":"One individual who took crystalline niacin had beneficial effects on lipid levels, while the other person who took a delayed release preparation had little lipid effect.","label":0,"label_text":"Not-Related"}
+{"text":"Lenalidomide is an immunomodulatory agent approved for use in patients with myelodysplastic syndrome, and in combination with dexamethasone for refractory or relapsed multiple myeloma.","label":0,"label_text":"Not-Related"}
+{"text":"Indeed, the reported annual number of imported malaria cases increased to not less than 100.","label":0,"label_text":"Not-Related"}
+{"text":"Catheter directed thrombolysis has been described as a treatment for large pulmonary emboli resistant to systemic therapy [Kelly P, Carroll N, Grant C, Barrett C, Kocka V.","label":0,"label_text":"Not-Related"}
+{"text":"The diagnosis of hypothermia was delayed until it was apparent for several days but resolved with the discontinuation of risperidone and continuation of clozapine.","label":1,"label_text":"Related"}
+{"text":"We report a case of a 72-year-old female who presented with hemoptysis, cough, and dyspnea.","label":0,"label_text":"Not-Related"}
+{"text":"Papilloedema and hepatic dysfunction apparently induced by perhexiline maleate (Pexid).","label":1,"label_text":"Related"}
+{"text":"Acute esmolol toxicity may be self-limiting because of its extremely short half-life.","label":1,"label_text":"Related"}
+{"text":"The authors describe the use of milnacipran for the treatment of chronic pain in a series of patients.","label":0,"label_text":"Not-Related"}
+{"text":"Secondary hyperparathyroidism in certain patients with lithium nephrotoxicity is also possible.","label":1,"label_text":"Related"}
+{"text":"Slit-lamp biomicroscopy and in vivo tandem scanning confocal microscopy were performed.","label":0,"label_text":"Not-Related"}
+{"text":"Four days after the initial injection of 3.6 mg of goserelin acetate, severe dyspnea developed due to worsening pleuritis carcinomatosa, which was considered as a flare-up.","label":1,"label_text":"Related"}
+{"text":"Agranulocytosis is a rare adverse effect associated with prolonged vancomycin therapy, and is potentially serious, especially in end stage renal disease (ESRD) patients.","label":1,"label_text":"Related"}
+{"text":"The patient received an intravitreal injection of approximately 20 mg of triamcinolone acetonide.","label":0,"label_text":"Not-Related"}
+{"text":"After a six-week course of low-dose cyclosporine A, she developed a severe but reversible loss of glomerular filtration rate and effective renal plasma flow despite of low cyclosporine A plasma levels.","label":1,"label_text":"Related"}
+{"text":"Diarrhoea, T-CD4+ lymphopenia and bilateral patchy pulmonary infiltrates developed in a male 60 yrs of age, who was treated with oxaliplatinum and 5-fluorouracil for unresectable rectum carcinoma.","label":1,"label_text":"Related"}
+{"text":"Lamotrigine toxicity secondary to sertraline.","label":1,"label_text":"Related"}
+{"text":"To our knowledge , this is the first reported case of bromide intoxication due to pyridostigmine bromide administration.","label":1,"label_text":"Related"}
+{"text":"Prominent eye movements during NREM sleep and REM sleep behavior disorder associated with fluoxetine treatment of depression and obsessive-compulsive disorder.","label":1,"label_text":"Related"}
+{"text":"A 66-year-old Japanese woman with severe scleroderma developed anemia and thrombocytopenia due to D-penicillamine (D-Pen) treatment, although the leukopenia was not markedly severe.","label":1,"label_text":"Related"}
+{"text":"Bradycardia and congestive heart failure associated with ocular timolol maleate.","label":1,"label_text":"Related"}
+{"text":"The second patient experienced mild nitritoid symptoms following several GSTM injections prior experiencing a cerebrovascular accident within several hours of her next injection.","label":1,"label_text":"Related"}
+{"text":"Accordingly, a practical and safe approach to MAOI dietary restrictions remains an essential component of patient management.","label":0,"label_text":"Not-Related"}
+{"text":"Pacemaker pocket infection due to acremonium species.","label":0,"label_text":"Not-Related"}
+{"text":"By the fifth day, a dramatic 7-fold increase was seen in the serum theophylline level (101.6 micromol\/L [18.3 microg\/mL]).","label":0,"label_text":"Not-Related"}
+{"text":"Examination showed a 7-cm mass and biopsy revealed angiosarcoma.","label":0,"label_text":"Not-Related"}
+{"text":"We report a patient diagnosed with B-CLL, previously treated with fludarabine, who developed TA-GVHD after being transfused during surgery for splenectomy.","label":0,"label_text":"Not-Related"}
+{"text":"This case report describes a patient who was previously prescribed alendronate (Fosamax) and presented with postoperative hypophosphatemia and hypocalcemic tetany after bowel preparation with Fleet Phospho-Soda.","label":1,"label_text":"Related"}
+{"text":"Her serum electrolytes were sodium 122 mEq\/L, potassium 5.9 mEq\/L, chloride 93 mEq\/L, and carbon dioxide 19 mEq\/L.","label":0,"label_text":"Not-Related"}
+{"text":"A 62-year-old Caucasian man with atrial fibrillation who was taking warfarin reported an episode of hematochezia; his international normalized ratio (INR) was 1.74.","label":1,"label_text":"Related"}
+{"text":"Pneumocystis carinii pneumonia as a complication of methotrexate treatment of asthma.","label":1,"label_text":"Related"}
+{"text":"These patients all underwent further evaluation of their pulmonary and allergic history and all 3 were challenged with aspirin.","label":0,"label_text":"Not-Related"}
+{"text":"Slow acetylators, who comprise roughly 50% of the South African population, are likely to develop clinical and biochemical features of phenytoin toxicity when this drug is given together with antituberculosis therapy.","label":1,"label_text":"Related"}
+{"text":"Acute diurnal variations of the pharmacodynamic striatal response are suggested explanation for these clinical observations.","label":0,"label_text":"Not-Related"}
+{"text":"Thrombolytic therapy may be a two-edged sword and therefore early angiography should be considered in making the diagnosis and choosing the therapy.","label":0,"label_text":"Not-Related"}
+{"text":"SMS 201-995 is active orally at doses of 4-8 mg and when given thrice-daily to 6 patients with active acromegaly, suppressed mean 24-h growth hormone levels by 51-88%.","label":0,"label_text":"Not-Related"}
+{"text":"Amlodipine and the nitroglycerin patch were discontinued and propafenone decreased to 450 mg\/d; citalopram was continued at 20 mg\/d.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was doing well at 6 months follow-up.","label":0,"label_text":"Not-Related"}
+{"text":"Diazepam use by pregnant women can be associated with a later presentation of withdrawal symptoms in the neonate than that induced by the use of other drugs.","label":1,"label_text":"Related"}
+{"text":"She was then placed on 1-month recall for the next 4 months.","label":0,"label_text":"Not-Related"}
+{"text":"A 14-year-old female developed systemic lupus erythematosus (SLE)-like symptoms, rash, fever, leukopenia and positive anti-nuclear antibody (ANA) two weeks after administration of carbamazepine (CBZ; Tegretol) used against benign Rolandic epilepsy.","label":1,"label_text":"Related"}
+{"text":"He had been taking trimethoprim-sulfamethoxazole for approximately eight days when he revisited his family physician, complaining of headaches, dizziness, difficulty with speech, weakness, and itching on the trunk of his body and legs, where a maculopapular rash was noted.","label":1,"label_text":"Related"}
+{"text":"Fatal spontaneous spinal epidural hematoma following thrombolysis for myocardial infarction.","label":0,"label_text":"Not-Related"}
+{"text":"A 7-year-old with congenital toxoplasmosis who took pyrimethamine and sulfadiazine for reactivated chorioretinitis developed fever, severe cutaneous involvement, swelling, abdominal pain and transaminitis, persisting weeks after withholding medicines.","label":1,"label_text":"Related"}
+{"text":"Although there is one case report of cholesterol crystal embolization following t-PA therapy with only extrarenal manifestations (N Engl J Med 321:1270, 1989), this is the first reported case of atheroembolic acute renal failure following t-PA therapy.","label":1,"label_text":"Related"}
+{"text":"Catheter-directed thrombolysis (CDT) has only been described in context with free-tissue transfer in a case of distal bypass salvage.","label":0,"label_text":"Not-Related"}
+{"text":"The hyperdense MCA lesion had resolved on the 24-hour follow-up scan.","label":0,"label_text":"Not-Related"}
+{"text":"The authors describe two cases of paranoid confusional psychosis commencing 1 week after the patients' withdrawal from sympathomimetic amines.","label":0,"label_text":"Not-Related"}
+{"text":"After 10 d cholinesterase was still low and liver enzymes were elevated.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: A complete response (CR) was obtained for all three patients, resulting in a response rate of 100%.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Clinicians should be aware of a risk of serotonin syndrome with serious extrapyramidal reactions in patients receiving sertraline or venlafaxine when metoclopramide is coadministered even in a single, conventional dose.","label":1,"label_text":"Related"}
+{"text":"Various reports show the use of MELISA (memory lymphocyte immunostimulation assay) and patch tests in determining mercury sensitivity.","label":0,"label_text":"Not-Related"}
+{"text":"Although Sweet's syndrome and SPE are rare diseases, the presence of these diseases must be considered when performing chemotherapy for urological malignancy.","label":0,"label_text":"Not-Related"}
+{"text":"Three ovarian thecomas, which are considered to be estrogenic tumors, were associated with endometrial malignant mullerian mixed tumor, mullerian adenosarcoma, and low-grade stromal sarcoma in postmenopausal women.","label":0,"label_text":"Not-Related"}
+{"text":"An extrapyramidal reaction was suspected and diphenhydramine 50 mg was administered without effect.","label":0,"label_text":"Not-Related"}
+{"text":"A case of a 32-year-old woman with aquagenic syringeal acrokeratoderma is presented.","label":0,"label_text":"Not-Related"}
+{"text":"Cataracts induced by intermittent Decadron used as an antiemetic.","label":1,"label_text":"Related"}
+{"text":"Acute pancreatitis is a rare but severe complication of TACE.","label":0,"label_text":"Not-Related"}
+{"text":"Hyperkalaemia with renal tubular dysfunction by oral therapy of sulfamethoxazole-trimethoprim (co-trimoxazole) is described in 2 elderly Japanese patients with lymphoid malignancy, who developed Pneumocystis carinii pneumonia and improved.","label":1,"label_text":"Related"}
+{"text":"Thus, if further studies confirm these effects, telmisartan may be the anti-hypertensive drug of first choice in HIV-infected subjects on combined antiretroviral therapy affected with diabetes and metabolic disorders.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To raise awareness of a rare but serious adverse effect of a commonly used medication.","label":0,"label_text":"Not-Related"}
+{"text":"5-Fluorouracil (5-FU) is an analogue of pyrimidine nucleosides that is widely used in the treatment of head and neck, breast, ovarian, and colon cancer.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a case of advanced ovarian carcinoma who developed difficulty walking because of marked pain in the lower extremities and loss of proprioception 25 days after treatment with weekly taxol (80 mg\/m(2)x3).","label":1,"label_text":"Related"}
+{"text":"During analysis of 28 patients receiving CAP with concomitant radiation (XRT) for pancreatic cancer (resected or locally advanced), two patients developed signs and symptoms consistent with peripheral neuropathy.","label":1,"label_text":"Related"}
+{"text":"This case suggests that acyclovir when given intravenously in doses of 10 mg\/kg may result in increased serum lithium concentrations.","label":1,"label_text":"Related"}
+{"text":"The patient was admitted to the intensive care unit for treatment of respiratory failure, where oxygen was delivered by face mask.","label":0,"label_text":"Not-Related"}
+{"text":"MATERIALS AND METHODS: We present two cases of significant morbidity related to primary and secondary perforation of the bladder following two instillations of epirubicin.","label":1,"label_text":"Related"}
+{"text":"The authors suggest that fluoxetine-induced akathisia may be caused by serotonergically mediated inhibition of dopaminergic neurotransmission and that the pathophysiology of fluoxetine-induced akathisia and tricyclic antidepressant-induced \"jitteriness\" may be identical.","label":1,"label_text":"Related"}
+{"text":"In this report, a patient who had undergone a renal transplantation as a result of malignant hypertension, and who was on immunosuppressive therapy consisting of cyclosporin, prednisone and azathioprine, developed thrombosis of the central retinal vein 5 years following the transplantation.","label":1,"label_text":"Related"}
+{"text":"Need for an urgent ultrasound examination for neck lump.","label":0,"label_text":"Not-Related"}
+{"text":"One tablet from 1 of the patient's levothyroxine prescriptions was assayed, and its levothyroxine content was 74.5% of the label claim, a value outside of the United States Pharmacopeia requirements of 90-110%.","label":0,"label_text":"Not-Related"}
+{"text":"Effects of the methylprednisolone pulse therapy on renal function.","label":0,"label_text":"Not-Related"}
+{"text":"Combination antidepressant therapy in primary care.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: We performed a clinical chart review.","label":0,"label_text":"Not-Related"}
+{"text":"The amount of weight loss was substantial in this group of patients, ranging from 19 pounds to 53 pounds.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Budesonide use can cause contact dermatitis.","label":1,"label_text":"Related"}
+{"text":"To our knowledge, this is the first case reported in the English literature of a generalized exanthem due to subcutaneous injection of enoxaparin.","label":1,"label_text":"Related"}
+{"text":"Dose-intensive chemotherapy with intravenous melphalan and growth-factor-mobilized blood stem cell support is feasible therapy for patients with AL amyloidosis, even when there is clinical evidence of cardiac involvement.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVES: To describe the dissolution of a large organized intraatrial catheter-tip thrombus using a novel aggressive dose escalation of tissue plasminogen activator infusion.","label":0,"label_text":"Not-Related"}
+{"text":"Future prospective controlled trials are needed to determine the efficacy, safety, tolerability, and possibly the optimal dose and timing of rFVIIa administration.","label":0,"label_text":"Not-Related"}
+{"text":"Alopecia does rarely develop in the convalescent status of phenobarbital-induced AHS after stopping phenobarbital and its mechanism is related to lymphocyte infiltration into the peri-bulbar, supra-bulbar and peri-follicular regions.","label":0,"label_text":"Not-Related"}
+{"text":"In addition to improving insulin sensitivity, they generally result in a modest elevation of plasma HDL cholesterol.","label":0,"label_text":"Not-Related"}
+{"text":"Sensorimotor polyneuropathy with 5-aminosalicylic acid: a case report.","label":1,"label_text":"Related"}
+{"text":"Systemic lupus erythematosus (SLE) developed in as 23-year-old woman with psoriasis during treatment with psoralen-ultraviolet-A (PUVA).","label":0,"label_text":"Not-Related"}
+{"text":"The diagnosis of lead toxicity is often delayed and abdominal pain is mistaken for acute abdomen.","label":0,"label_text":"Not-Related"}
+{"text":"All three were doing well at the time of follow-up evaluation, and there was no evidence of structural heart disease.","label":0,"label_text":"Not-Related"}
+{"text":"No chronic GVHD occurred.","label":0,"label_text":"Not-Related"}
+{"text":"In vivo confocal microscopy is a useful tool to study interlamellar stromal keratopathy induced by elevated IOP after LASIK in humans and the response to treatment and to differentiate interlamellar stromal keratopathy from DLK.","label":0,"label_text":"Not-Related"}
+{"text":"Using this approach, we observed normal haemostasis, and there were no signs of excessive postoperative bleeding or wound haematoma.","label":0,"label_text":"Not-Related"}
+{"text":"The cardiac toxicity of HCQ has focused primarily on acute intoxication.","label":0,"label_text":"Not-Related"}
+{"text":"This may be particularly useful in the patient with asymptomatic pharyngoesophageal diverticulum (Zenker diverticulum).","label":0,"label_text":"Not-Related"}
+{"text":"Effective therapy of HIT involves both the prompt recognition of the syndrome and its proper management.","label":0,"label_text":"Not-Related"}
+{"text":"MR findings in methotrexate-induced CNS abnormalities.","label":1,"label_text":"Related"}
+{"text":"Since toxicity develops with a remarkable delay, early removal of the drug (by hemodialysis) could possibly prevent central nervous toxicity.","label":0,"label_text":"Not-Related"}
+{"text":"It is likely that the selective nephrotoxicity in these 3 patients with SIADH was induced by tetracycline.","label":0,"label_text":"Not-Related"}
+{"text":"In this case, a 51-year-old woman presented with several weeks of left shoulder pain and was diagnosed with rotator cuff tendonitis.","label":0,"label_text":"Not-Related"}
+{"text":"The prevalence of use, demographics of a treatment population, and occurrence of a particular side effect are explored in this article.","label":0,"label_text":"Not-Related"}
+{"text":"This case illustrates the importance of screening for parasitic infections before transplantation in the appropriate clinical setting, and demonstrates the utility of direct diagnostic evaluation for parasitic infections in at-risk post-transplant patients with unexplained illnesses.","label":0,"label_text":"Not-Related"}
+{"text":"Acute pancreatitis associated with danazol treatment for endometriosis.","label":1,"label_text":"Related"}
+{"text":"Severe bleomycin lung toxicity: reversal with high dose corticosteroids.","label":1,"label_text":"Related"}
+{"text":"The only comparable case previously reported (Lai et al., 1991) showed close similarities in the clinical, biological and histological manifestations with microvesicular steatosis.","label":0,"label_text":"Not-Related"}
+{"text":"Toxicity associated with barracuda is discussed.","label":0,"label_text":"Not-Related"}
+{"text":"Heparin was replaced by argatroban on the 13th day.","label":0,"label_text":"Not-Related"}
+{"text":"It is concluded that simultaneous administration of ciprofloxacin and tazobactam\/piperacillin may cause marked thrombocytosis.","label":1,"label_text":"Related"}
+{"text":"Co-trimoxazole red cell aplasia in leukaemia.","label":1,"label_text":"Related"}
+{"text":"DISCUSSION: Cough induced by ACE inhibitors is a frequently documented adverse effect.","label":0,"label_text":"Not-Related"}
+{"text":"Steroid therapy for ureteral obstruction after aortoiliac graft surgery.","label":0,"label_text":"Not-Related"}
+{"text":"One patient with nasopharyngeal undifferentiated carcinoma and 1 patient with maxillary adenosquamous carcinoma showed complete response (CR), while all SCC patients showed stable disease (SD) or progressive disease (PD).","label":0,"label_text":"Not-Related"}
+{"text":"Hypotension and sinus arrest with nifedipine in pulmonary hypertension.","label":1,"label_text":"Related"}
+{"text":"However, extracutaneous lesions are common, and the gastrointestinal tract is often involved.","label":0,"label_text":"Not-Related"}
+{"text":"Fatal acute neurotoxicity is rarely encountered.","label":0,"label_text":"Not-Related"}
+{"text":"Patients treated with captopril who develop \"atypical cholangitis\" should be suspected of having captopril-associated liver damage.","label":1,"label_text":"Related"}
+{"text":"The duration of the pauses were equal or almost equal to one short plus one long P-P interval or to twice the basic sinus cycle.","label":0,"label_text":"Not-Related"}
+{"text":"Dentists need to be alert to the risk that patients may not reveal their true medical history.","label":0,"label_text":"Not-Related"}
+{"text":"Studies performed 10 years ago on 25 patients with MTX-induced liver cirrhosis indicated that this type of cirrhosis was not of an aggressive nature.","label":1,"label_text":"Related"}
+{"text":"Total body computed tomography scan did not reveal any mucosal or visceral lesion.","label":0,"label_text":"Not-Related"}
+{"text":"During the disease course, the patient showed a transient increase in anti-human herpesvirus (HHV)-6 antibody titers and HHV-6 DNA in the peripheral blood, indicating the reactivation of a latent HHV-6 infection.","label":0,"label_text":"Not-Related"}
+{"text":"This report presents a potential case of risperidone-induced tardive dyskinesia.","label":1,"label_text":"Related"}
+{"text":"Subacromial injections have been used to treat rotator cuff problems.","label":0,"label_text":"Not-Related"}
+{"text":"Gingival hemorrhage, myelodysplastic syndromes, and acute myeloid leukemia.","label":0,"label_text":"Not-Related"}
+{"text":"Special care should be taken when pulmonary symptoms appear in association with ticlopidine treatment.","label":1,"label_text":"Related"}
+{"text":"OBJECTIVE: To describe the use of botulinum toxin injection of the lacrimal gland for palliative treatment of epiphora secondary to canalicular obstruction from docetaxel therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Neurological diseases have been rarely described as adverse events of anti-TNF agents.","label":0,"label_text":"Not-Related"}
+{"text":"This is the first case of hydroxyurea-induced acute interstitial pneumonitis reported in the literature.","label":1,"label_text":"Related"}
+{"text":"Ataxia caused by propafenone has been reported to the pharmaceutical companies and drug monitoring agencies, but has not been well described or emphasized in the medical literature.","label":1,"label_text":"Related"}
+{"text":"Aquagenic pruritus is a rare but distinct entity in which intense itching develops after contact with water, in the absence of cutaneous signs or underlying disorders that could explain the symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"Similar cases of this reaction have been reported with procainamide, which is structurally similar to metoclopramide.","label":0,"label_text":"Not-Related"}
+{"text":"All patients had significant renal insufficiency.","label":0,"label_text":"Not-Related"}
+{"text":"The patient's receipt of concurrent anti-TNF-alpha therapy and other immunosuppressive therapy while she was living in an area where histoplasmosis was endemic was thought to be the most likely explanation for the infection; the evidence presented suggests that this fatal infection was unlikely to have been related to exposure to the agent administered in the gene-therapy trial.","label":0,"label_text":"Not-Related"}
+{"text":"We report the cases of two patients, previously operated for mitral mechanical valve replacement who developed thrombosis of the prosthesis.","label":0,"label_text":"Not-Related"}
+{"text":"The baby had an excellent recovery and was discharged home after a prolonged antibiotic course.","label":0,"label_text":"Not-Related"}
+{"text":"Except for 3 mild infections around the catheter exit site, there have been no complications of this therapy is 58 cumulative patient weeks.","label":0,"label_text":"Not-Related"}
+{"text":"Neutropenia and agranulocytosis are risks known to occur with phenothiazines and clozapine.","label":1,"label_text":"Related"}
+{"text":"These changes resemble lymphocytic bronchiolitis in lung transplant recipients, which was well correlated with HRCT findings.","label":0,"label_text":"Not-Related"}
+{"text":"Anterior spinal artery syndrome--a complication of cervical intrathecal phenol injection.","label":1,"label_text":"Related"}
+{"text":"Bronchial exposure to alternative sprays containing beclomethasone dipropionate (group D), fluticasone-17- propionate (D) and dexamethasone-21-isonicotinate (C) was well tolerated.","label":0,"label_text":"Not-Related"}
+{"text":"She began to recover after 10 days of supportive therapy and was discharged several weeks later on primidone therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Didanosine (ddl) was the most common ART drug being used by 4 patients.","label":0,"label_text":"Not-Related"}
+{"text":"PVT during chemotherapy in children is a rare event and appears to be closely related to intensive chemotherapy containing busulfan and to be associated with HVOD.","label":1,"label_text":"Related"}
+{"text":"The syndrome, diagnostic modalities, and therapeutic options are reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVES: A 56-year-old man developed an erythematous, circle-shaped lesion on his penis.","label":0,"label_text":"Not-Related"}
+{"text":"She manifested all the clinical symptoms and signs of caffeine toxicity.","label":0,"label_text":"Not-Related"}
+{"text":"Losartan-induced angioedema.","label":1,"label_text":"Related"}
+{"text":"Cutaneous necrosis as a result of interferon alfa is an infrequent complication with unknown pathogenesis, in which a cutaneous local immune-mediated inflammatory process might be involved.","label":1,"label_text":"Related"}
+{"text":"Although RFA is generally well tolerated, recent studies have reported complications associated with RFA.","label":0,"label_text":"Not-Related"}
+{"text":"This case report describes successful lithium treatment in a patient with long-standing periodic catatonia.","label":0,"label_text":"Not-Related"}
+{"text":"A patient is reported who developed essential thrombocythemia after successful treatment for hairy cell leukemia.","label":0,"label_text":"Not-Related"}
+{"text":"Rifabutin therapy has been demonstrated to be effective in the treatment and prophylaxis of MAC infection.","label":0,"label_text":"Not-Related"}
+{"text":"We report here a case of cardiovascular and neurological depression induced by oxymetalzoline in a toddler.","label":1,"label_text":"Related"}
+{"text":"ARDS has been associated with the administration of other monoclonal antibodies, such as infliximab, gemtuzumab ozogamicin, and OKT3 and is believed to be directly mediated by release of proinflammatory cytokines.","label":1,"label_text":"Related"}
+{"text":"Despite poor prognostic factors and extensive white matter lesions, the patient recovered dramatically with no need for maintenance steroid therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Terbinafine is given as continuous dosing, 250 mg per day for 3 months.","label":0,"label_text":"Not-Related"}
+{"text":"Carbamazepine was discontinued and the patient remained asymptomatic.","label":0,"label_text":"Not-Related"}
+{"text":"The prognosis of Mycobacterium avium complex (MAC) infection has been improved by new macrolides-containing regimens and the use of highly active antiretroviral therapy (HAART) in the treatment of acquired immunodeficiency syndrome (AIDS).","label":0,"label_text":"Not-Related"}
+{"text":"The patient revived 1 1\/2 hours after treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Long-term clinical outcome after accidental overdose of multiple chemotherapeutic agents.","label":0,"label_text":"Not-Related"}
+{"text":"Disseminated Aspergillus terreus infection arising from cutaneous inoculation treated with caspofungin.","label":0,"label_text":"Not-Related"}
+{"text":"A case of drug-induced hypersensitivity syndrome showing transient immunosuppression before viral reactivation during treatment for pemphigus foliaceus.","label":0,"label_text":"Not-Related"}
+{"text":"The first neurological symptoms like paraesthesia, severe hyperpathia of the legs and mild to heavy spinal ataxia occurred after an average time of treatment of 78 days and a mean dosage of 52 g.","label":0,"label_text":"Not-Related"}
+{"text":"Reflex sympathetic dystrophy syndrome in renal transplanted patients under immunosuppression with tacrolimus.","label":1,"label_text":"Related"}
+{"text":"Clonidine is being used increasingly for treatment of spasticity in patients with spinal cord injury.","label":0,"label_text":"Not-Related"}
+{"text":"A case of aseptic pleuropericarditis in a patient with chronic plaque psoriasis under methotrexate therapy.","label":1,"label_text":"Related"}
+{"text":"Paecilomyces lilacinus infection in a liver transplant patient: case report and review of the literature.","label":0,"label_text":"Not-Related"}
+{"text":"The dose was adjusted to 1 g every 12 hours during continuous venovenous hemodialysis.","label":0,"label_text":"Not-Related"}
+{"text":"A CT of the thorax revealed newly developed bilateral pulmonary ground-glass opacity corresponding to the previous radiation fields.","label":0,"label_text":"Not-Related"}
+{"text":"All had a muscle biopsy, but only one showed the classical rimmed vacuoles.","label":0,"label_text":"Not-Related"}
+{"text":"She was diagnosed as TOS by digital subtraction angiography.","label":0,"label_text":"Not-Related"}
+{"text":"Excessive use of salbutamol inhalers is described in two young people with asthma, a girl and a boy both aged 15 years.","label":0,"label_text":"Not-Related"}
+{"text":"In a patient suffering from rheumatoid arthritis, we report the first simultaneous occurrence of two side effects of low-dose methotrexate: an acute megaloblastic anaemia and a pneumonitis.","label":1,"label_text":"Related"}
+{"text":"Ethambutol toxicity manifesting as acute onset psychosis.","label":1,"label_text":"Related"}
+{"text":"Following a reduction in the doses of these drugs, the symptoms and signs related to the superior sagittal sinus thrombosis gradually subsided, and the haematological pictures remained in remission.","label":0,"label_text":"Not-Related"}
+{"text":"We report in detail an unusual adverse reaction to infliximab therapy, a drug-induced lupus-like clinical syndrome.","label":1,"label_text":"Related"}
+{"text":"The renal function of the baby was completely recovered, without systemic antifungal treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Alteration of speech is a rare but distressing complication of orthotopic liver transplantation (OLT).","label":0,"label_text":"Not-Related"}
+{"text":"Thrombophilia in the face of endocarditis should be treated with a suspicion of underlying cancer.","label":0,"label_text":"Not-Related"}
+{"text":"Simvastatin therapy was resumed and resulted in a prompt and severe return of his symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"The right time to perform surgery is hard to define.","label":0,"label_text":"Not-Related"}
+{"text":"Concentrations of brompheniramine and dextromethorphan were measured in both postmortem blood and liver specimens using a gas chromatograph equipped with a nitrogen-phosphorus detector.","label":0,"label_text":"Not-Related"}
+{"text":"Disulfiram-like reactions with newer cephalosporins: cefmenoxime.","label":1,"label_text":"Related"}
+{"text":"A heparin-like effect was suspected.","label":0,"label_text":"Not-Related"}
+{"text":"The outcome was fatal in both patients.","label":0,"label_text":"Not-Related"}
+{"text":"In the presence of risk factors, such as cGVHD, prophylactic treatment for toxoplasmosis should be reinstituted; Trimethoprim-sulfamethoxasole most probably prevented earlier reactivation of toxoplasmosis in our patient.","label":0,"label_text":"Not-Related"}
+{"text":"After the correction of hyponatremia, due to the high liver enzyme levels, he was diagnosed as rhabdomyolysis.","label":0,"label_text":"Not-Related"}
+{"text":"Intraoperative anaphylaxis: verba volant, scripta manent!","label":0,"label_text":"Not-Related"}
+{"text":"Interferon (IFN) is the most widely prescribed drug of choice for chronic hepatitis B infection, which is a common health problem in our country.","label":0,"label_text":"Not-Related"}
+{"text":"Cyclosporin therapy in Mooren's ulcer.","label":0,"label_text":"Not-Related"}
+{"text":"The elimination half-time (15 h) was similar to that reported for end-stage renal disease patients, while the steady-state volume of distribution (85 l) and the area under the curve concentration (127 mg\/l.h) were greater.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of disseminated Scedosporium\/Pseudallescheria infection due to Pseudallescheria boydii sensu stricto after lung transplantation in a patient with cystic fibrosis.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: We report a patient with symptoms of small bowel obstruction whose diagnosis was confirmed by previous operation owing to a well-known pathology due to an unusual reason, perforation, which was masqueraded by therapeutic drugs.","label":0,"label_text":"Not-Related"}
+{"text":"We report a patient in whom the anti-depressant trazodone hydrochloride (Molipaxin, Roussel), a serotonin antagonist, provoked generalized pustular psoriasis (GPP).","label":1,"label_text":"Related"}
+{"text":"A 6-month-old girl was treated with FK506 after undergoing living donor liver transplantation for fulminant hepatitis.","label":0,"label_text":"Not-Related"}
+{"text":"The role played by repeated drug prescriptions from general practitioners without appropriate clinical and laboratory controls, and that of our patient's depression are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Clinicians should be aware of a risk of serotonin syndrome with serious extrapyramidal reactions in patients receiving sertraline or venlafaxine when metoclopramide is coadministered even in a single, conventional dose.","label":1,"label_text":"Related"}
+{"text":"Hemorrhagic myocardial infarction complicated by free wall-rupture: a case associated with unusual clinical features following intravenous thrombolytic therapy.","label":0,"label_text":"Not-Related"}
+{"text":"DISCUSSION: The pathogenesis of fixed drug eruption and the role of MIF assay in the diagnosis of adverse drug reaction is discussed.","label":0,"label_text":"Not-Related"}
+{"text":"Complete removal of all foreign material is essential, however when prosthesis removal is not possible or contraindicated, suppressive antibiotic therapy with retention of the functioning hip arthroplasty may be considered.","label":0,"label_text":"Not-Related"}
+{"text":"Recurrent hyponatremia associated with citalopram and mirtazapine.","label":1,"label_text":"Related"}
+{"text":"Lethargy in a newborn: lithium toxicity or lab error?","label":1,"label_text":"Related"}
+{"text":"Management of upper gastrointestinal haemorrhage complicating dual anti-platelet therapy.","label":0,"label_text":"Not-Related"}
+{"text":"The episode lasted 1 week and was followed by a dramatic fall in plasma sodium (104 mEq I-1), associated with a proportionally lesser decrease in plasma chloride and phosphate.","label":0,"label_text":"Not-Related"}
+{"text":"It is concluded that hypoparathyroid patients being treated with vitamin D and calcium should be carefully monitored in the case of an intercurrent illness or a change in medication.","label":0,"label_text":"Not-Related"}
+{"text":"Once benefit occurred, we discontinued or reduced other anticataplectic medication.","label":0,"label_text":"Not-Related"}
+{"text":"He had hypokalemia (K 2.3 mmol\/L) induced by licorice and also had received disopyramide for arrhythmia, bicalutamide for prostate cancer, and silodosin for prostate hypertrophy.","label":1,"label_text":"Related"}
+{"text":"We report the case of a patient who developed polyserositis (pericardial effusion, pleural effusion, and pericarditis) after being started on clozapine, and whose symptoms remitted upon discontinuation of clozapine.","label":1,"label_text":"Related"}
+{"text":"We have used anti-angiogenetic therapy with thalidomide in two AILD patients and observed remarkable responses.","label":0,"label_text":"Not-Related"}
+{"text":"A 54-year-old man with polyarteritis nodosa developed acute onset of right upper quadrant abdominal pain associated with a large liver mass.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Hydroxyurea is a cytostatic agent used to treat myeloproliferative disorders and long-term treatment is associated with mucocutaneous adverse events and nail hyperpigmentation.","label":1,"label_text":"Related"}
+{"text":"Central venous catheter (CVC)-related infections were most frequent (n = 20) followed by otitis externa (n = 6) and pneumonia (n = 5).","label":0,"label_text":"Not-Related"}
+{"text":"Three of the 4 patients with hydrocephalus secondary to CNS tumor suffered secondary shunt complications during periods of severe neutropenia resulting from chemotherapy (6 weeks to 6 months after shunt insertion).","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Delay in clinical recognition and treatment in our first case resulted in death due to multiorgan failure (MOF).","label":0,"label_text":"Not-Related"}
+{"text":"With this therapy the clinical manifestations of Reiter's Syndrome disappeared but sudden abdominal and bronchopulmonary symptoms complicated the picture and the patient died in a septical shock.","label":0,"label_text":"Not-Related"}
+{"text":"Xanthomonas maltophilia endophthalmitis after cataract extraction.","label":0,"label_text":"Not-Related"}
+{"text":"Therefore, the critical care nurse must have knowledge of the implications of administering standard antiarrhythmic agents if this patient reverts into a tachyarrhythmia.","label":0,"label_text":"Not-Related"}
+{"text":"Subsequent studies have not shown convincing evidence for a strong association with beta-blocker use and depression.","label":0,"label_text":"Not-Related"}
+{"text":"Most reactions develop cutaneously.","label":0,"label_text":"Not-Related"}
+{"text":"The patient reported herein strengthens the association between the 22q11.2 deletion spectrum and Evans syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"An increasing range of drugs have been reported to cause sAML, including the alkylating agents, the epipodophyllotoxins and the anthracyclines, both as single agents and in combination (Pedersen-Bjergaard & Philip, 1991; Pedersen-Bjergaard & Rowley, 1994).","label":0,"label_text":"Not-Related"}
+{"text":"Potential causes of methamphetamine-related keratitis can be divided into four categories resulting from (a) direct pharmacologic and physical effects of methamphetamine; (b) the toxic effects of diluting or \"cutting\" agents such as lidocaine and quinine; (c) effects related to the route of drug administration (intravenous, inhalation, smoking); and (d) manufacture-related effects of exposure to unintentional caustic contaminants in the final product.","label":1,"label_text":"Related"}
+{"text":"A case of disseminated Aspergillus terreus infection in a patient with prolonged neutropenia after stem cell transplant for myeloma is reported.","label":0,"label_text":"Not-Related"}
+{"text":"Dipyridamole stress testing may be used in the diagnosis of coronary artery disease and risk assessment of patients who are unable to exercise.","label":0,"label_text":"Not-Related"}
+{"text":"The unusually though potentially life-threatening possibility of heart failure secondary to anti-TNF use in ankylosing spondylitis merits attention.","label":0,"label_text":"Not-Related"}
+{"text":"The causal relationship between the drug and the eruption has been based mainly on circumstantial evidence and is further strengthened by the positive result of one or two in vitro tests: the macrophage migration inhibition (MIF) test and the indirect rat mast cell degranulation (MCD) test.","label":0,"label_text":"Not-Related"}
+{"text":"He further reduced his dosage to 15 mg every morning on days 13 and 14 of varenicline therapy, and his supply of amphetamine-dextroamphetamine was depleted on day 15.","label":0,"label_text":"Not-Related"}
+{"text":"Gastrointestinal (GI) tract disease is an unusual presentation of this yeast infection.","label":0,"label_text":"Not-Related"}
+{"text":"Although moderate myelosuppression is not uncommonly seen in patients treated with lenalidomide, aplastic anemia has not previously been reported to be associated with this agent.","label":1,"label_text":"Related"}
+{"text":"Four subsequently did well on clozapine therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Troglitazone-induced fulminant hepatic failure.","label":1,"label_text":"Related"}
+{"text":"Treatment with an epidural blood patch (EBP) via the caudal approach resulted in complete relief of symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"Strongyloides stercoralis infection is known to be important because of its potential for life-threatening disseminated infection in immunosuppressed hosts.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment for her breast cancer had included surgery, radiation and chemotherapy with doxorubicin and cyclophosphamide.","label":0,"label_text":"Not-Related"}
+{"text":"He stated he was fit and well and denied taking any medications.","label":0,"label_text":"Not-Related"}
+{"text":"Cervical artery dissection (CAD) recurrences are rare but the risk could be higher during the first month.","label":0,"label_text":"Not-Related"}
+{"text":"Metformin was stopped.","label":0,"label_text":"Not-Related"}
+{"text":"Typically, drug-induced neutropenia occurs in a patient receiving a semisynthetic penicillin for two weeks or more.","label":1,"label_text":"Related"}
+{"text":"A critical review of the treatment regimen and prophylaxis for C1-inhibitor deficiency is presented, and three new cases are described.","label":0,"label_text":"Not-Related"}
+{"text":"However, peripheral neuropathy and bone marrow depression led to linezolid withdrawal in seven patients, and neuropathy may not be fully reversible in all patients.","label":1,"label_text":"Related"}
+{"text":"Both of the Campylobacter jejuni isolates were resistant to cotrimoxazole and ciprofloxacin.","label":0,"label_text":"Not-Related"}
+{"text":"Amiodarone-induced dysthyroidism.","label":1,"label_text":"Related"}
+{"text":"After the third injection to the abdomen, the patient developed a rash, and after the fourth and fifth injections to other areas of the abdomen, injection-site papules were seen.","label":0,"label_text":"Not-Related"}
+{"text":"These arrhythmias were resistant to standard antiarrhythmic therapy.","label":0,"label_text":"Not-Related"}
+{"text":"This case series demonstrates that secondary open-angle glaucoma can be a sight-threatening consequence, and periorbital steroids should therefore be used cautiously and sparingly, particularly in those with a family history of glaucoma.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was started on increasing doses of levothyroxine for subclinical hypothyroidism.","label":0,"label_text":"Not-Related"}
+{"text":"Ritonavir can induce glucuronidation of several medications including ethinyl estradiol, levothyroxine, and lamotrigine.","label":0,"label_text":"Not-Related"}
+{"text":"In the two new cases, the causality assessment was judged as \"possible\" according to the RUCAM score.","label":0,"label_text":"Not-Related"}
+{"text":"Persistent segmental cutaneous anesthesia after a brown recluse spider bite.","label":0,"label_text":"Not-Related"}
+{"text":"The median follow-up exceeded 7 years and 72% of these patients had received prior alkylating agent therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Symptoms cleared after drug withdrawal and repeated testing produced no claudication.","label":0,"label_text":"Not-Related"}
+{"text":"Other upper tract neoplasms after cyclophosphamide are reviewed.","label":1,"label_text":"Related"}
+{"text":"We report a third case of a 6-week-old infant with Escherichia coli sepsis who received ampicillin and other antibiotics and subsequently developed TEN.","label":1,"label_text":"Related"}
+{"text":"Pustular psoriasis-like tinea incognito due to Trichophyton rubrum.","label":0,"label_text":"Not-Related"}
+{"text":"Sporadic rippling muscle disease unmasked by simvastatin.","label":1,"label_text":"Related"}
+{"text":"Aortic thrombosis resolved with enoxaparin in a patient treated with cisplatin-based regimen for small cell lung cancer.","label":0,"label_text":"Not-Related"}
+{"text":"Skin rash began after 2 weeks of treatment, and signs of hepatocellular failure developed 3 weeks after phenobarbital had been started.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND: Etanercept is a tumor necrosis factor (TNF) inhibitor that has been licensed in the United States for the treatment of adult and juvenile rheumatoid arthritis as well as psoriatic arthritis.","label":0,"label_text":"Not-Related"}
+{"text":"No woman was affected.","label":0,"label_text":"Not-Related"}
+{"text":"On the fifth day of tocolysis with magnesium sulfate, nifedipine, terbutaline and betamethasone, edema developed in both labia.","label":1,"label_text":"Related"}
+{"text":"The patient failed to respond to treatment with a conventional dosage of a lipid formulation of amphotericin B (lifoAmB; 5 mg\/kg\/day) given alone or in combination with itraconazole, and he responded only to an aggressive strategy that included a very high dosage of lifoAmB (15 mg\/kg\/day) given in combination with itraconazole as well as a rapid reduction in immunosuppression.","label":0,"label_text":"Not-Related"}
+{"text":"The trachea was immediately intubated and the lungs ventilated with oxygen 40% for four hours.","label":0,"label_text":"Not-Related"}
+{"text":"He is known to have had epilepsy since childhood.","label":0,"label_text":"Not-Related"}
+{"text":"Hypersensitivity to the drug has not been reported.","label":0,"label_text":"Not-Related"}
+{"text":"Three cases of gold-related neuropathy are reported.","label":1,"label_text":"Related"}
+{"text":"Five days of treatment with ketoconazole alone was ineffective in our patient's infection.","label":0,"label_text":"Not-Related"}
+{"text":"The authors describe a case of combined lithium and haloperidol toxicity characterized by hyperpyrexia, severe rigidity, mutism, and development of irreversible tardive dyskinesia.","label":1,"label_text":"Related"}
+{"text":"Pericarditis and cardiac arrhythmias developed, but the patient did not have cardiac tamponade.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients with ovarian cancer who had received multiple courses of cisplatin without complications experienced hypersensitivity reactions to cisplatin: one, involving intrahepatic artery infusion, manifested general erythema, dyspnea, and hypotension; the other, involving intravenous infusion, manifested abdominal pain, general erythema, and fever.","label":1,"label_text":"Related"}
+{"text":"Lithium serum level was within the therapeutic range.","label":0,"label_text":"Not-Related"}
+{"text":"Further studies are needed to determine the optimal dose and schedule of DMSO application and to assess its efficacy in extravasation injuries from other vesicants.","label":0,"label_text":"Not-Related"}
+{"text":"However, we did not know of the previous tragedies nor had we fully understood how critical examination of some of our own earlier near misses could have made such a tragic mistake less likely to occur.","label":0,"label_text":"Not-Related"}
+{"text":"We present two such case of epilepsy induced by video game.","label":0,"label_text":"Not-Related"}
+{"text":"Because high AUCs of 4-hydroxycyclophosphamide, thiotepa\/tepa and carboplatin correlate with increased toxicity, the treatment risk in this obese patient was significantly increased.","label":0,"label_text":"Not-Related"}
+{"text":"Coronary vasospasm resulting from a sudden autonomic response associated with an intracranial procedure was encountered during percutaneous radiofrequency trigeminal rhizotomy.","label":0,"label_text":"Not-Related"}
+{"text":"Accidental intrathecal injection of the wrong drug was suspected and a used ampule of tranexamic acid discovered in the trash can.","label":0,"label_text":"Not-Related"}
+{"text":"This has rarely been reported before in the literature.","label":0,"label_text":"Not-Related"}
+{"text":"Capecitabine-induced headache responding to diltiazem.","label":1,"label_text":"Related"}
+{"text":"After treatment with dose-intensive intravenous melphalan followed by infusion of autologous growth-factor-mobilized blood stem cells, clinical evaluations and plasma cell studies were repeated at 3 and 12 months.","label":0,"label_text":"Not-Related"}
+{"text":"We report a 40-year-old man who presented with acute onset of hemophagocytic syndrome (HPS) after allogeneic bone marrow transplantation (alloBMT) for acute myelogenous leukemia.","label":0,"label_text":"Not-Related"}
+{"text":"Recombinant VIIa concentrate in the management of bleeding following prothrombin complex concentrate-related myocardial infarction in patients with haemophilia and inhibitors.","label":1,"label_text":"Related"}
+{"text":"A lumbar myelography was carried out, and a dorsal block was demonstrated.","label":0,"label_text":"Not-Related"}
+{"text":"Stent fracture: an unusual cause of late restenosis after sirolimus-eluting stent placement.","label":0,"label_text":"Not-Related"}
+{"text":"A few round Russell bodies were seen in the first biopsy specimen and none in the third.","label":0,"label_text":"Not-Related"}
+{"text":"A 16-year-old boy developed fever, generalized rigidity, leukocytosis, and increased serum transaminase and creatine kinase levels while receiving treatment with olanzapine and lithium.","label":1,"label_text":"Related"}
+{"text":"A case report.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of a 20-year-old female with polyarteritis nodosa (PAN) who developed bilateral sensorineural hearing loss 25 minutes after receiving 30 mg of intravenous ketoralac.","label":1,"label_text":"Related"}
+{"text":"A diagnosis of sarcoidosis was determined from a lung biopsy.","label":0,"label_text":"Not-Related"}
+{"text":"Intrapericardial infusion of 5-fluorouracil.","label":0,"label_text":"Not-Related"}
+{"text":"Augmentation, defined as a loss of circadian recurrence with progressively earlier daily onset and increase in the duration, intensity, and anatomy of symptoms, not compatible with the half-life of the drug, is associated with dopaminergic treatment in restless legs syndrome (RLS) patients.","label":0,"label_text":"Not-Related"}
+{"text":"An episode of leukoencephalopathy is reported in a 13-year-old girl who, after standard radiotherapy for a posterior fossa medulloblastoma, received 8 treatments with a protocol containing a 4-hour infusion of 500 mg\/m2 methotrexate and 12 mg intrathecal methotrexate.","label":1,"label_text":"Related"}
+{"text":"PURPOSE: The case of a patient who developed aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension simultaneously during treatment with trimethoprim-sulfamethoxazole is described.","label":1,"label_text":"Related"}
+{"text":"We recommend strict monitoring of serum antiepileptic drug (AED) levels to avoid toxicity and inadequate seizure control.","label":0,"label_text":"Not-Related"}
+{"text":"This report suggests that bleomycin lung toxicity may be reversible if treated aggressively.","label":1,"label_text":"Related"}
+{"text":"The symptoms disappeared when desipramine was discontinued and in one case returned when desipramine treatment was reinitiated.","label":0,"label_text":"Not-Related"}
+{"text":"The thrombus causing the liver infarction was detected as a low echoic mass by transesophageal echocardiography at the right coronary sinus.","label":0,"label_text":"Not-Related"}
+{"text":"Atypical ventricular tachycardia (torsade de pointes) induced by amiodarone: arrhythmia previously induced by quinidine and disopyramide.","label":1,"label_text":"Related"}
+{"text":"The patient remains free of arrhythmia 15 months after the event with the combination of propranolol and amiodarone.","label":0,"label_text":"Not-Related"}
+{"text":"Sodium phenylbutyrate was added to treatment with HU in two patients, but failed to produce an increase in total Hb despite increasing Hb F levels.","label":1,"label_text":"Related"}
+{"text":"Chemotherapy related fatal neurotoxicity during induction in acute lymphoblastic leukemia.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of Sweet's syndrome in association with sargramostim treatment following chemotherapy for acute myelogenous leukemia.","label":1,"label_text":"Related"}
+{"text":"Topical hydroquinone is used in the treatment of a number of skin conditions.","label":0,"label_text":"Not-Related"}
+{"text":"Previously reported cases of persistent proximal right umbilical vein have shown a variety of other malformations but a single umbilical artery has been the most consistent.","label":0,"label_text":"Not-Related"}
+{"text":"Russell bodies in contact-lens-associated giant papillary conjunctivitis.","label":0,"label_text":"Not-Related"}
+{"text":"No sedative or anxiolytic effect comparable to minor or major tranquilizers could be observed.","label":0,"label_text":"Not-Related"}
+{"text":"Therefore, although garenoxacin reportedly causes fewer adverse reactions for cardiac rhythms than third-generation quinolone antibiotics, one must be cautious of the interference of other drugs during hypokalemia in order to prevent TdP.","label":1,"label_text":"Related"}
+{"text":"Thrombosed prosthetic valve in tricuspid position.","label":0,"label_text":"Not-Related"}
+{"text":"The AVM was embolized without incident, however, the AVF was not accessible.","label":0,"label_text":"Not-Related"}
+{"text":"Stopping further solvent exposure failed to improve his condition.","label":0,"label_text":"Not-Related"}
+{"text":"We observed 5 reactions in 3 patients that appear to be related to a high dose-infusion time ratio, indicating that dose and rate of infusion may be important factors in precipitating anaphylactoid reactions with cisplatin.","label":1,"label_text":"Related"}
+{"text":"CASE SUMMARY: TLS developed in 2 neonates born at 38 weeks' gestational age; both were managed in part with rasburicase.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To test the hypothesis that tumor necrosis factor (TNF)-alpha may mediate the loss and the dedifferentiation of subcutaneous fat tissue in the insulin-induced lipoatrophies of a diabetic patient who presented extensive lesions.","label":1,"label_text":"Related"}
+{"text":"Systemic drug toxicity is unusual when FUdR is given via HAI, and neurologic toxicity has not previously been reported.","label":0,"label_text":"Not-Related"}
+{"text":"Despite these changes, the sensitivity of the mutant virus to zanamivir assessed by a standard test in MDCK cells was unaffected.","label":0,"label_text":"Not-Related"}
+{"text":"All three patients experienced remission of their disease at the time of the occurrence of marrow aplasia.","label":0,"label_text":"Not-Related"}
+{"text":"The literature is reviewed and the treatment implications are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"Intestinal wall thickness, evaluated by ultrasound, is an important prognostic factor which could act as a guide to surgical indication.","label":0,"label_text":"Not-Related"}
+{"text":"2. The plasma cortisol level was significantly higher in the low-dose period (mean 13.90 +\/- 3.35 micrograms\/ml) than in the high-dose period (mean 9.06 +\/- 2.75 micrograms\/ml) although, paradoxically, the panic attack frequency was significantly lower in the low-dose period (mean 1.35 +\/- 0.29\/day) than in the high-dose period (mean 2.09 +\/- 0.66\/day).","label":0,"label_text":"Not-Related"}
+{"text":"Risperidone-induced psychosis and depression in a child with a mitochondrial disorder.","label":1,"label_text":"Related"}
+{"text":"Three of 50 patients treated with isotretinoin (1 mg\/kg\/day) for cystic acne complained of poor night vision and\/or excessive glare sensitivity.","label":1,"label_text":"Related"}
+{"text":"Current antiamoebal therapy was effective and regrafting in the quiet eye was successful.","label":0,"label_text":"Not-Related"}
+{"text":"We cared for a patient with progressive renal impairment who presented with blurred vision, QRS broadening and cardiac failure due to chronic cibenzoline intoxication.","label":1,"label_text":"Related"}
+{"text":"In the absence of other causes, we suspected an adverse reaction to amiodarone, not least because of the similarity with histologic findings of cases previously reported.","label":0,"label_text":"Not-Related"}
+{"text":"Based on our experience and on previously published data, serum ammonia levels appear to be indicated in all ED patients on valproic acid therapy who present with altered mental status.","label":1,"label_text":"Related"}
+{"text":"These changes, in combination with care providers' fear of opioids, often lead to the inappropriate use of antagonists, such as naloxone.","label":0,"label_text":"Not-Related"}
+{"text":"Pelvic arterial pseudoaneurysm is generally treated by laparotomy and hemostatic sutures or by uterine artery embolization.","label":0,"label_text":"Not-Related"}
+{"text":"Some degree of biochemical improvement was also noted in the other cases in whom the blood lactate levels before treatment were 15, 17, and 31 mM.","label":0,"label_text":"Not-Related"}
+{"text":"During treatment with alefacept, the patient's psoriasis improved markedly without exacerbation of his photosensitive SCLE lesions.","label":0,"label_text":"Not-Related"}
+{"text":"PATIENTS AND METHODS: Progressive renal dysfunction developed in two adolescent black girls with high-risk ALL who underwent renal biopsies that were consistent with FSGS.","label":0,"label_text":"Not-Related"}
+{"text":"Histologic assessment of pleural fluid revealed no malignancy and results of video-assisted thoracoscopic surgery were normal.","label":0,"label_text":"Not-Related"}
+{"text":"Acute myeloid leukemia and lung cancer occurring in a chronic lymphocytic leukemia patient treated with fludarabine and autologous peripheral blood stem-cell transplantation.","label":1,"label_text":"Related"}
+{"text":"On days 2-6, the patient experienced a myocardial infarction, ischemic cerebrovascular accident, recurrent lower extremity arterial thrombus, and splenic infarct.","label":0,"label_text":"Not-Related"}
+{"text":"Injury to the spinal cord injury with paraplegia, is a rare complication of surgical repair of aortic coarctation recognized immediately post-operatively.","label":0,"label_text":"Not-Related"}
+{"text":"A skeletal X-ray showed huge amounts of periarticular TC.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: This case illuminates a possible role of UV therapy in the induction of pemphigus herpetiformis through an epitope-spreading mechanism.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of pulmonary toxoplasmosis after heart transplant despite the prophylactic anti-toxoplasmic treatment that was given but was not sufficient to prevent toxoplasmosis.","label":0,"label_text":"Not-Related"}
+{"text":"Following repair of the graft override on postoperative day 42, the epithelial defect healed.","label":0,"label_text":"Not-Related"}
+{"text":"Subsequent testing revealed that this patient has an extremely low level of DPD activity (0.015 nmol\/min\/mg protein; mean, 0.189 nmol\/min\/mg protein).","label":0,"label_text":"Not-Related"}
+{"text":"Acute myelogenous leukemia following treatment of invasive cervix carcinoma: a case report and a review of the literature.","label":0,"label_text":"Not-Related"}
+{"text":"SUBSEQUENT COURSE: The nephrosis resolved almost completely once the interferon was stopped and after immunosuppressive treatment.","label":1,"label_text":"Related"}
+{"text":"Thrombosis, leiomyoma and GnRH-a therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Although differential diagnostic alternatives can be considered in all described cases it is very likely that vincristine does cause severe visual loss in a small number of patients.","label":1,"label_text":"Related"}
+{"text":"RESULTS: A 69-year-old Saudi man underwent penetrating keratoplasty with donor tissue that was culture-positive for Candida glabrata.","label":0,"label_text":"Not-Related"}
+{"text":"CASE DESCRIPTION: A 21-year-old male was initially evaluated because of a large mass that had been growing for 7 months.","label":0,"label_text":"Not-Related"}
+{"text":"Our patient, diagnosed with persistent ovarian carcinoma, had a peritoneal Tenckoff catheter placed for chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: The patients in our series improved significantly when the serotonin antagonist cyproheptadine was added to their regimens.","label":0,"label_text":"Not-Related"}
+{"text":"The only adverse effect was seroconversion of anti-hepatitis C virus after receiving 108 bottles of LC for 36 weeks.","label":0,"label_text":"Not-Related"}
+{"text":"The currently reported cases are the first observed clinical activity of a kinase inhibitor against the T315I phenotype.","label":0,"label_text":"Not-Related"}
+{"text":"Motor fluctuations appear after 2-3 years of levodopa treatment, and affect at least 50% of patients after five years.","label":1,"label_text":"Related"}
+{"text":"Histological and immunohistochemical studies of paraffin embedded specimen were conducted.","label":0,"label_text":"Not-Related"}
+{"text":"Tiagabine (Gabitril) is a unique anticonvulsant that is prescribed for a variety of psychiatric disorders.","label":0,"label_text":"Not-Related"}
+{"text":"Bronchospasm did not recur, making it unlikely that tartrazine hypersensitivity caused this problem.","label":0,"label_text":"Not-Related"}
+{"text":"Fluorescein angiogram showed presence of venous collaterals, but the pattern of the edema was atypical; optical coherence tomography (OCT) and indocyanine green angiography (ICG) were used to confirm the diagnosis of CNV.","label":0,"label_text":"Not-Related"}
+{"text":"Intraperitoneal chromic phosphate is widely used as adjuvant therapy in the treatment of early-stage ovarian epithelial carcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"A patient with ulcerative colitis developed skin pigmentation and diffuse pulmonary shadowing without respiratory symptomatology, while taking sulfasalazine.","label":1,"label_text":"Related"}
+{"text":"This patient was treated successfully by surgical excision of the affected segment of ileum together with intravenous ganciclovir.","label":0,"label_text":"Not-Related"}
+{"text":"He sustained a myocardial infarction on postoperative day 7 and progressively deteriorated and expired five days later.","label":0,"label_text":"Not-Related"}
+{"text":"Until the mechanism of the formation of rickets in small premature infants is clarified it is recommended that supplemental calcium and vitamin D be given to all premature infants receiving parenteral nutrition, and that periodic x-rays be obtained to detect the development of rickets.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a case of EGE manifested as an allergy to gemfibrozil.","label":1,"label_text":"Related"}
+{"text":"We present a case report of a patient with typhoid fever who experienced a hypersensitivity reaction subsequent to the infusion of chloramphenicol sodium succinate.","label":1,"label_text":"Related"}
+{"text":"Both patients were successfully treated with propylthiouracil (PTU) and dexamethasone (DXT).","label":0,"label_text":"Not-Related"}
+{"text":"Biochemical, bacteriological and imaging studies were performed for specific diagnosis.","label":0,"label_text":"Not-Related"}
+{"text":"The predisposing factors for toxicity are hypoalbuminemia, chronic renal failure, hepatic dysfunction and drugs which interfere with phenytoin metabolism.","label":0,"label_text":"Not-Related"}
+{"text":"Signs of severe liver disease included elevated aminotransferases, conjugated hyperbilirubinemia, significant coagulopathy, hepatosplenomegaly and ascites.","label":0,"label_text":"Not-Related"}
+{"text":"Mental illness in mild PKU responds to biopterin.","label":0,"label_text":"Not-Related"}
+{"text":"The presence of diabetes constitutes a cluster of particularly high cardiovascular risks in patients, both regarding diabetic damage and hypertensive damage.","label":0,"label_text":"Not-Related"}
+{"text":"Dental treatment is rarely associated with such an event.","label":0,"label_text":"Not-Related"}
+{"text":"She was admitted for observation and all symptoms resolved within 12 h of admission.","label":0,"label_text":"Not-Related"}
+{"text":"Severe microangiopathic hemolytic anemia, thrombocytopenia, and renal impairment were each noted in about 90% of the cases.","label":0,"label_text":"Not-Related"}
+{"text":"Animal studies are necessary to evaluate this observation and potential disadvantages of hydrocortisone usage.","label":0,"label_text":"Not-Related"}
+{"text":"It has been demonstrated that bisphosphonate-based supportive therapy (pamidronate or zoledronate) reduces skeletal events (onset or progression of osteolytic lesions) both in patients with multiple myeloma (MM) and in cancer patients with bone metastasis.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: Review of medical records for 4 patients presenting retinochoroiditis and evidence of T. gondii infection.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: The estimated number of Accutane prescriptions for reproductive-aged women has more than doubled in the past 10 years; it is the most widely used teratogenic drug in the United States, with approximately 2.5 per 1,000 reproductive-aged women exposed to Accutane in 1999.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: This novel chemotherapy regimen achieved favorable results and may be useful in treating patients with unresectable multifocal HCC resistant to TAE.","label":0,"label_text":"Not-Related"}
+{"text":"They also demonstrate the possibility of durable complete remission of post-ASCT PTLD following antiviral and immune modulating therapy.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: Significant weight loss is a potential adverse event in patients with rheumatoid arthritis treated with leflunomide.","label":1,"label_text":"Related"}
+{"text":"METHODS: Four white female infants with sight-threatening periocular hemangiomata received a combination of steroid injections of triamcinolone and betamethasone.","label":0,"label_text":"Not-Related"}
+{"text":"Sustained and nonsustained ventricular tachycardia: genesis, significance, and management.","label":0,"label_text":"Not-Related"}
+{"text":"Recent evidence also suggests that these same medications enhance the patient's response to acute migraine therapies, and may also reduce the likelihood of developing chronic daily headache.","label":0,"label_text":"Not-Related"}
+{"text":"CT scan of muscles showed similar cysticerci producing a 'honeycomb' appearance.","label":0,"label_text":"Not-Related"}
+{"text":"Her platelet counts were never less than 75% of baseline and were consistently above 200 x 10(3)\/mm(3).","label":0,"label_text":"Not-Related"}
+{"text":"Hepatoxicity is a rare complication of SRL therapy and may be connected with some diagnostic and\/or therapeutic problems.","label":1,"label_text":"Related"}
+{"text":"Earlier reports documented similar symptoms in patients without a history of heart failure.","label":0,"label_text":"Not-Related"}
+{"text":"The pathophysiological mechanisms remain unknown, although the drug could act through massive cytokines liberation after destruction of CD20 positive cells by rituximab.","label":1,"label_text":"Related"}
+{"text":"Celiac disease diagnosis was performed and symptoms and laboratory abnormalities improved after gluten-free diet.","label":0,"label_text":"Not-Related"}
+{"text":"Posterior reversible encephalopathy syndrome (PRES) induced by cyclosporine use in a patient with collapsing focal glomeruloesclerosis.","label":1,"label_text":"Related"}
+{"text":"The fetal valproate syndrome (FVS) is characterized by distinctive facial appearance, major and minor malformations, and developmental delay.","label":1,"label_text":"Related"}
+{"text":"A well-recognized complication of ethambutol use is optic neuropathy, but the potential ocular toxicity of isoniazid is often overlooked.","label":1,"label_text":"Related"}
+{"text":"These features have not previously been reported as side effects of glibenclamide therapy, but intrahepatic cholestasis may occur with chlorpropamide, a similar sulphonylurea agent.","label":1,"label_text":"Related"}
+{"text":"Lumbar spinal cord stimulation for cervical-originated central pain: a case report.","label":0,"label_text":"Not-Related"}
+{"text":"Repeat standardized neurodevelopmental assessments (Peabody and Griffith scales) at 13 and 19 months were normal and magnetic resonance spectra no longer detected the previously observed lipid resonance.","label":0,"label_text":"Not-Related"}
+{"text":"Commonly, opioid drugs are administered in patients with acute cholecystitis to relieve pain.","label":0,"label_text":"Not-Related"}
+{"text":"Even if an oral multivitamin preparation is given instead of MVI, patients with malabsorption may not absorb thiamine adequately.","label":0,"label_text":"Not-Related"}
+{"text":"An unusual response to progestin therapy of hyperplasia.","label":0,"label_text":"Not-Related"}
+{"text":"Prolonged responses were achieved with low doses of HU (3-10 mg\/kg\/day) and higher doses were associated with mild reversible hematologic or hepatic toxicity and no further increases in Hb.","label":1,"label_text":"Related"}
+{"text":"DESIGN: Case report.","label":0,"label_text":"Not-Related"}
+{"text":"16 patients with cutaneous or subcutaneous melanoma recurrence on an extremity were treated with regional perfusion with Melphalan.","label":0,"label_text":"Not-Related"}
+{"text":"We believe that methotrexate represents a relatively effective alternative to surgery in patients with early unruptured tubal pregnancy, but suggest that it be used with caution in view of possible systemic toxicity.","label":0,"label_text":"Not-Related"}
+{"text":"Ciclosporin was effective at controlling all symptoms of SNHL.","label":0,"label_text":"Not-Related"}
+{"text":"Then, she told, the slight pain and the reddened area which developed around the injection site disappeared completely and he turned back to his daily activities.","label":0,"label_text":"Not-Related"}
+{"text":"Visceral leishmaniasis is rare among patients under immunosuppressive therapies, and even more among patients under anti-TNF-alpha treatment, where only four cases have been described.","label":0,"label_text":"Not-Related"}
+{"text":"Recently, UFT has been extensively studied for colorectal, pancreatic, and various types of cancer in North America and Europe, especially with leukovorin.","label":0,"label_text":"Not-Related"}
+{"text":"The mechanisms and occurrence of lymphoma after immune response modifiers are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"Pancreatic enzymes were discontinued, and she was given a low-fat, high-carbohydrate diet with satisfactory weight gain.","label":0,"label_text":"Not-Related"}
+{"text":"CASE PRESENTATION: A 46-year-old man consulted his doctor due to symptoms of depression.","label":0,"label_text":"Not-Related"}
+{"text":"METHOD: Onset, course, and outcome of the patient's eye disease were analyzed.","label":0,"label_text":"Not-Related"}
+{"text":"Review of the literature showed similar occurrences in other patients.","label":0,"label_text":"Not-Related"}
+{"text":"The concomitant use, however, of colchicine and statin has been associated with the rapid onset of muscle weakness.","label":1,"label_text":"Related"}
+{"text":"A causal relationship is strongly suggested by the mode of onset, the absence of a previous history of catatonia, and the rapid resolution of the syndrome within 72 hours of discontinuance of the disulfiram therapy.","label":0,"label_text":"Not-Related"}
+{"text":"In vivo confocal microscopy showed swollen and enlarged cellular structures and the presence of microlacunae separating the stromal collagen lamellae.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was a nonsmoker with no respiratory illnesses.","label":0,"label_text":"Not-Related"}
+{"text":"Yoga neuropathy.","label":0,"label_text":"Not-Related"}
+{"text":"We describe the case of an 82 year old woman developing severe respiratory functional impairment after open heart surgery and subsequent surgical pericardial drainage inducing diaphragmatic spasm and successfully treated with gabapentin.","label":0,"label_text":"Not-Related"}
+{"text":"Perioperative records were reviewed for use of topical 1:1000 epinephrine and for any intraoperative or postoperative complications related to its use.","label":0,"label_text":"Not-Related"}
+{"text":"The doses were 3,000, 6,000, or 12,000 U\/day.","label":0,"label_text":"Not-Related"}
+{"text":"Rupture of the plantar fascia in athletes engaged in sports that require running and jumping has been reported.","label":0,"label_text":"Not-Related"}
+{"text":"Quinupristin\/dalfopristin and voriconazole controlled Staphylococcus epidermidis pneumonia and chronic necrotizing aspergillosis in a patient with severe lung degradation consequent to multiple treatments for Hodgkin's lymphoma.","label":0,"label_text":"Not-Related"}
+{"text":"This patient was treated with endovascular stenting of the dissections along with cessation of ergot.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Despite treatment with various neuroleptics, the psychosis resolved only when the interferon\/ribavirin were discontinued.","label":0,"label_text":"Not-Related"}
+{"text":"Within six hours the patient had a partial relapse which resolved completely following further intravenous dantrolene 2 mg\/kg.","label":0,"label_text":"Not-Related"}
+{"text":"We experienced 2 cases of mequitazine-induced photosensitivity reaction in patients who took mequitazine for their dermatologic problems.","label":1,"label_text":"Related"}
+{"text":"Hydroxyzine alone caused an insignificant delay.","label":0,"label_text":"Not-Related"}
+{"text":"Evidence-based mental health use of anticonvulsants during pregnancy.","label":0,"label_text":"Not-Related"}
+{"text":"A patient with chronic myeloid leukaemia treated with busulphan for 4-5 years, developed signs of busulphan toxicity and portal hypertension with ascites, oesophageal varices and jaundice.","label":1,"label_text":"Related"}
+{"text":"Topical corticosteroids used for dermatological conditions around the face and eyes are often regarded as being fairly innocuous with regard to ocular side-effects.","label":0,"label_text":"Not-Related"}
+{"text":"Pentamidine is one of two agents currently used to treat infections with Pneumocystis carinii.","label":0,"label_text":"Not-Related"}
+{"text":"The history of desmopressin use was still not available.","label":0,"label_text":"Not-Related"}
+{"text":"Ten hours after the second methotrexate injection, the patient experienced a diffuse pruritic papular eruption located mainly on the limbs.","label":1,"label_text":"Related"}
+{"text":"Caspofungin, a beta-1,3-glucan synthesis inhibitor, has shown activity against the cyst forms of P. jiroveci in experimental animal models.","label":0,"label_text":"Not-Related"}
+{"text":"Physicians must consider this when prescribing these medications for patients with misdirected eyelashes.","label":0,"label_text":"Not-Related"}
+{"text":"In addition, immunohistochemical findings of a dense CD8+, TIA1+ and granzyme B+ lymphoid infiltrate within a biopsied lesion provide indirect evidence of functional T-cell activation induced by treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Severe Raynaud's phenomenon with yohimbine therapy for erectile dysfunction.","label":1,"label_text":"Related"}
+{"text":"Drug-induced gingival hyperplasia is well documented within the literature.","label":0,"label_text":"Not-Related"}
+{"text":"A crusty cause of prosthetic valve endocarditis.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of a 13-year-old boy who was known to have Fanconi's anemia for five years.","label":0,"label_text":"Not-Related"}
+{"text":"No invasive vascular procedure had been performed.","label":0,"label_text":"Not-Related"}
+{"text":"Methylphenidate (Ritalin)-associated cataract and glaucoma.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: The new quinolone derivatives (levofloxacin, sparfloxacin, grepafloxacin, trovafloxacin, gatifloxacin and moxifloxacin), also called gyrase inhibitors, are known for their potential to cause central nervous system-related adverse effects, including headache, dizziness and insomnia.","label":1,"label_text":"Related"}
+{"text":"Hypocomplementemia and transient evidence of vasculitis suggested the presence of immunecomplexes.","label":0,"label_text":"Not-Related"}
+{"text":"In each case, some degree of recovery followed discontinuation of the statin medication.","label":0,"label_text":"Not-Related"}
+{"text":"The asthma resolved within 24 hours following three albuterol inhalations.","label":0,"label_text":"Not-Related"}
+{"text":"Early clinical suspicion and availability of CT or magnetic resonance imaging for prompt diagnosis are essential to initiate appropriate medical therapy and timely surgery.","label":0,"label_text":"Not-Related"}
+{"text":"We present three prednisolone-treated boys with myoglobinuria and in two cases this was recurrent.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of ELP in children is generally supportive, with the symptoms and roentgenographic abnormalities resolving within months after stopping the use of mineral oil.","label":1,"label_text":"Related"}
+{"text":"A 25-year-old woman with rheumatoid arthritis for the past 5 years started to develop gradual enlargement of her breasts 15 months before presentation.","label":0,"label_text":"Not-Related"}
+{"text":"The new drug had been added to the long-standing treatment with risperidone.","label":0,"label_text":"Not-Related"}
+{"text":"In patients with chronic heart failure, spironolactone added to conventional treatment may lead to serious and, occasionally, fatal hyperkalaemia.","label":1,"label_text":"Related"}
+{"text":"Examination revealed a fully conscious patient with slight dyspnoea and mild wheezing which responded to oxygen 30% and nebulised bronchodilators.","label":0,"label_text":"Not-Related"}
+{"text":"Unusual late pulmonary complication in a child after umbilical cord blood transplantation: high-resolution CT-pathologic correlation.","label":0,"label_text":"Not-Related"}
+{"text":"CASE: A 71-year-old man without immunodeficiency developed corneal endotheliitis in the right eye.","label":0,"label_text":"Not-Related"}
+{"text":"CASE SUMMARY: We report a case of a 73-year-old postmenopausal woman with stage T2N0M0 breast cancer.","label":0,"label_text":"Not-Related"}
+{"text":"There was neither a recurrence of cytomegalovirus retinitis nor an occurrence of retinal detachment during the 9-month follow-up after intravenous ganciclovir therapy.","label":0,"label_text":"Not-Related"}
+{"text":"As more women of childbearing age are being identified as HIV infected, vertical transmission to the fetus and\/or neonate is an increasingly significant therapeutic problem.","label":0,"label_text":"Not-Related"}
+{"text":"However, we recently saw two patients with renal tuberculosis treated with ethambutol in whom visual loss from toxic optic neuropathies was severe and irreversible despite careful ophthalmological monitoring and prompt discontinuation of the agent at the first sign of impaired visual function.","label":1,"label_text":"Related"}
+{"text":"Organisms that may be associated with an enteric source should prompt a thorough gastrointestinal evaluation.","label":0,"label_text":"Not-Related"}
+{"text":"Giant cell lichenoid dermatitis is a recently described pathological entity, which can be seen as an unusual lichenoid drug eruption, a manifestation of sarcoidosis or within herpes zoster scars.","label":0,"label_text":"Not-Related"}
+{"text":"Single photon emission computed tomography (SPECT) revealed a low density of presynaptic dopamine transporters in our patient's brain.","label":0,"label_text":"Not-Related"}
+{"text":"All cases were diagnosed with Acanthamoeba castellanii by culture on nonnutrient agar, corneal scraping, and\/or confocal microscopy.","label":0,"label_text":"Not-Related"}
+{"text":"Many augmentation strategies have been tried in the past with varying levels of success or safety.","label":0,"label_text":"Not-Related"}
+{"text":"The symptoms and biochemical abnormality improved after gradual discontinuation of carbamazepine.","label":0,"label_text":"Not-Related"}
+{"text":"A 47-year-old woman with a history of breast cancer presented with eruptive cutaneous nodules on the trunk and extremities.","label":0,"label_text":"Not-Related"}
+{"text":"Significant dose reduction was possible in all three without loss of asthma control, emphasising the importance of back-titration to minimise dose.","label":0,"label_text":"Not-Related"}
+{"text":"On this mechanistic basis, we treated three consecutive patients with metastatic PEComa with an oral mTOR inhibitor, sirolimus.","label":0,"label_text":"Not-Related"}
+{"text":"Case report: lack of control of diabetes and weight gain in a patient on initiation and rechallenge of therapy with olanzapine.","label":1,"label_text":"Related"}
+{"text":"The ocular toxicity of DCF, previously described as conjunctivitis, appears to be a keratitis of moderate severity which requires further study.","label":1,"label_text":"Related"}
+{"text":"Quinine-induced hearing loss.","label":1,"label_text":"Related"}
+{"text":"PURPOSE: To report a case of severe corticosteroid-induced glaucoma after intravitreal injection of triamcinolone acetate in a 34-year-old man without a history of glaucoma.","label":1,"label_text":"Related"}
+{"text":"\"B\" was an 11-year-old girl with mild mental retardation and aggression who was treated with risperidone 1 mg per day.","label":0,"label_text":"Not-Related"}
+{"text":"The pathophysiology for this unusual disorder may be agonist-induced dopamine receptor hypersensitivity.","label":0,"label_text":"Not-Related"}
+{"text":"The patient tolerated the chemotherapy well and did not develop any skin or nail changes during that period of time.","label":0,"label_text":"Not-Related"}
+{"text":"Unfortunately, the access device frequently provides a foci for debilitating infections.","label":0,"label_text":"Not-Related"}
+{"text":"Corticosteroids should be used in low doses and with great caution in scleroderma patients.","label":0,"label_text":"Not-Related"}
+{"text":"INFVA was screened in NPA and\/or bronchoalveolar lavage using IF in all BMT recipients having respiratory symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"This patient had no evidence of previous neurologic disease.","label":0,"label_text":"Not-Related"}
+{"text":"Her primary care physician had earlier made a preliminary diagnosis of pertussis and prescribed a short course of azithromycin and corticosteroids, which did not help relieve the symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"A patient with intracranial osteosarcoma that arose 16 years after radiation therapy for hereditary retinoblastoma developed fatal cerebral edema and brainstem herniation after she received a single dose of intravenous methotrexate.","label":1,"label_text":"Related"}
+{"text":"Quetiapine-induced myoclonus.","label":1,"label_text":"Related"}
+{"text":"In our two patients, we investigated NAT2* genotypes by the polymerase chain reaction-restriction fragment length polymorphism method.","label":0,"label_text":"Not-Related"}
+{"text":"She had received seven courses of chemotherapy, with a cumulative doxorubicin dose of 500 mg\/m(2) over 5 months, resulting in minimal tumor regression.","label":0,"label_text":"Not-Related"}
+{"text":"As the child's adoptive parents controlled medication access, they were investigated by social welfare agencies.","label":0,"label_text":"Not-Related"}
+{"text":"Median time to progression (TTP) was 12 weeks.","label":0,"label_text":"Not-Related"}
+{"text":"Apart from this, the patient also showed clinical signs of obstructive sleep apnea syndrome that was confirmed by polysomnographic study.","label":0,"label_text":"Not-Related"}
+{"text":"Twenty-six patients with mycosis fungoides were treated topically with three nitrosourea compounds: carmustine (BCNU), lomustine (CCNU), and 1-methyl-1-nitrosourea.","label":0,"label_text":"Not-Related"}
+{"text":"Aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension in a patient treated with trimethoprim-sulfamethoxazole.","label":1,"label_text":"Related"}
+{"text":"Each case (stage IB and IA) occurred after initiation of the subcutaneous anti-tumor necrosis factor medications etanercept and adalimumab, respectively.","label":0,"label_text":"Not-Related"}
+{"text":"The addition of intrathecal methotrexate to treatment protocols has increased survival rates in children with acute lymphoblastic leukemia but is also associated with varying degrees of neurotoxicity.","label":1,"label_text":"Related"}
+{"text":"Acute myocardial infarction due to coronary spasm associated with L-thyroxine therapy.","label":1,"label_text":"Related"}
+{"text":"The patients were not experiencing rebound phenomena at the onset of treatment with naratriptan.","label":0,"label_text":"Not-Related"}
+{"text":"Drug induced myopathies have been implicated with the use of several medications.","label":0,"label_text":"Not-Related"}
+{"text":"A healthy, 30-year-old man, exposed to sulindac on two separate occasions, had an incapacitating isolated idential sensory neuropathy.","label":1,"label_text":"Related"}
+{"text":"The right eye was regrafted three months after the recurrence and penetrating keratoplasty was done two years later in the left eye.","label":0,"label_text":"Not-Related"}
+{"text":"We report here two cases of dyserythropoietic anaemia associated with long-term linezolid use that share striking similarities to chloramphenicol-associated myelotoxicity.","label":1,"label_text":"Related"}
+{"text":"Use of the Naranjo probability scale determined the association between cephalosporin use and leukopenia to be probable.","label":1,"label_text":"Related"}
+{"text":"Our data suggest that low-molecular-weight heparin possesses strong renoprotective properties, thus confirming previous data from experimental nephropathies.","label":0,"label_text":"Not-Related"}
+{"text":"Both patients manifested other symptoms consistent with parkinsonian syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Four of the 14 women did not have pregnancy tests before starting Accutane.","label":0,"label_text":"Not-Related"}
+{"text":"CASE SUMMARY: A 42-year-old African American woman with metastatic breast cancer developed progressive disease.","label":0,"label_text":"Not-Related"}
+{"text":"Only 13 SLE patients with AMI caused by coronary artery aneurysms have been reported, 11 of whom were young or middle-aged women and the 2 remaining were young men.","label":0,"label_text":"Not-Related"}
+{"text":"In two patients in whom conventional therapy failed, clotrimazole was successful in controlling recurrent infection following penetrating keratoplasty.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To report the case of a patient with a prior allergy to a sulfonamide antibiotic who subsequently developed the same reaction when administered various loop diuretics.","label":0,"label_text":"Not-Related"}
+{"text":"In conclusion, the present case report illustrates a novel manifestation of chronic granulomatous disease.","label":0,"label_text":"Not-Related"}
+{"text":"The Karnofsky score calculated in 29 patients showed improvement in all patients except those aged greater than 70 years.","label":0,"label_text":"Not-Related"}
+{"text":"Influence of physiologic hormonal modification and of hormonal treatment in a patient with a history of migraine with aura.","label":0,"label_text":"Not-Related"}
+{"text":"Liposomal amphotericin B was prescribed at the standard dose of 5 mg\/kg\/day; however, amphotericin B deoxycholate 5 mg\/kg was inadvertently administered (usual dose of the deoxycholate formulation is 0.5-0.8 mg\/kg\/day).","label":0,"label_text":"Not-Related"}
+{"text":"Oral adverse effects due to the use of Nevirapine.","label":0,"label_text":"Not-Related"}
+{"text":"Hypersensitivity to carboplatin has been reported in up to 44% of patients receiving this antineoplastic agent, usually occurring after several courses of treatment.","label":1,"label_text":"Related"}
+{"text":"The blocked catheter was surgically explanted and the firm material inside was analyzed.","label":0,"label_text":"Not-Related"}
+{"text":"Lymphoma usually responds well to multiagent chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Human insulin-induced lipoatrophy.","label":1,"label_text":"Related"}
+{"text":"Recent studies have found clozapine a highly effective and ECT a possibly useful intervention.","label":0,"label_text":"Not-Related"}
+{"text":"All 3 marrow specimens demonstrated moderate to marked diffuse reticulin fibrosis with more than 20% blasts.","label":0,"label_text":"Not-Related"}
+{"text":"A 10-year-old boy was diagnosed with ADHD and had received methylphenidate hydrochloride, 60 mg\/day for 2 years.","label":0,"label_text":"Not-Related"}
+{"text":"Stanozolol was well tolerated and had minimal side effects.","label":0,"label_text":"Not-Related"}
+{"text":"Subacute cholestatic hepatitis likely related to the use of senna for chronic constipation.","label":1,"label_text":"Related"}
+{"text":"An encephalopathy and cardiomyopathy developed in a seventeen-year-old girl with chemotherapy-induced renal failure while receiving an intravesical aluminum infusion for hemorrhagic cystitis.","label":1,"label_text":"Related"}
+{"text":"We present a case of HUS in an advanced ovarian cancer patient treated with carboplatin and gemcitabine, and described its favorable outcome after chemotherapy interruption and supportive care with a 1 year follow-up.","label":1,"label_text":"Related"}
+{"text":"Fixed drug eruption of the scrotum due to methylphenidate.","label":1,"label_text":"Related"}
+{"text":"Strong expressions of PDGF-B and IGF-1 on alveolar macrophages and type II pneumocytes were clearly demonstrated, but in contrast, the expressions of TGF-beta1 and COX-2 were almost undetectable.","label":0,"label_text":"Not-Related"}
+{"text":"Clostridium difficile colitis associated with cisplatin-based chemotherapy in ovarian cancer patients.","label":1,"label_text":"Related"}
+{"text":"The child died 62 days after discontinuation of prostaglandin treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Dosing in these patients requires very careful management.","label":0,"label_text":"Not-Related"}
+{"text":"On examination, rigors, shallow inspirations, and chills were noted.","label":0,"label_text":"Not-Related"}
+{"text":"Photochemotherapy using psoralen and ultraviolet (UV)A irradiation (PUVA) is a useful treatment method for vitiligo.","label":0,"label_text":"Not-Related"}
+{"text":"In addition, gabapentin treatment enhanced the frequency of hypothermic episodes in a separate patient with known hypothalamic dysfunction.","label":0,"label_text":"Not-Related"}
+{"text":"Heart rate, blood pressure, nausea ratings, and the occurrence of emesis were recorded during 18 chemotherapy treatments over a 9 month period.","label":0,"label_text":"Not-Related"}
+{"text":"Gradually, her immune status and ocular symptoms improved.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Opioid based cough mixtures are readily available to the public and are generally used safely.","label":0,"label_text":"Not-Related"}
+{"text":"His inhibitor was increased from 15 to 580 BU within the first 4 weeks of immune tolerance.","label":0,"label_text":"Not-Related"}
+{"text":"After appropriate antibiotic and replacement of the central venous line, CT demonstrated disappearance of the lung nodules in all three patients, enabling a diagnosis of nodular septic embolism.","label":0,"label_text":"Not-Related"}
+{"text":"Esophageal candidiasis following omeprazole therapy: a report of two cases.","label":1,"label_text":"Related"}
+{"text":"General practitioners frequently find themselves caught between the desire to treat and relieve symptoms, and not wanting to cause or exacerbate dependence.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To describe a probable case of transient global amnesia caused by propafenone.","label":1,"label_text":"Related"}
+{"text":"Case 1, a 62-year-old woman, developed bilateral optic neuritis with decreased sensation of vibration and increased deep tendon reflex in the lower extremities after a seven-month use of recombinant interferon alpha-2a for chronic active hepatitis C.","label":1,"label_text":"Related"}
+{"text":"During the course of treatment, photosensitisation by clofazimine led to a dermatological disease resembling actinic dermatitis.","label":0,"label_text":"Not-Related"}
+{"text":"Administration of an angiotensin II receptor antagonist (ARB) during the second trimester of pregnancy is known to cause irreversible renal damage in the fetus.","label":0,"label_text":"Not-Related"}
+{"text":"Methotrexate inhibits the enzyme dihydrofolate reductase and prevents the formation of DNA and RNA.","label":0,"label_text":"Not-Related"}
+{"text":"In the present paper, we report on two siblings with G6PD deficiency who developed haemolytic anaemia following topical application of henna to their whole body to treat skin lesions.","label":0,"label_text":"Not-Related"}
+{"text":"Secondary leukemia with a translocation (8;21)?","label":0,"label_text":"Not-Related"}
+{"text":"When the trazodone was reduced, the involuntary movements promptly ceased.","label":1,"label_text":"Related"}
+{"text":"We report a fatal case of toxic epidermal necrolysis (TEN) resulting from a high dose of cytosine arabinoside (ARA-C).","label":1,"label_text":"Related"}
+{"text":"Human immunodeficiency virus type 1 (HIV-1) p24 antigen was detected at the beginning of 5 of the 6 treatment courses.","label":0,"label_text":"Not-Related"}
+{"text":"Ototoxicity was assumed, but the deficit was later found to be of a conductive nature, due to marrow proliferation within the ossicular chain as a consequence of the disease process--a phenomenon previously unreported in the literature.","label":0,"label_text":"Not-Related"}
+{"text":"Cerebral hemorrhage from amyloid angiopathy and coronary thrombolysis.","label":0,"label_text":"Not-Related"}
+{"text":"Acute renal failure required dialysis but with subsequent recovery.","label":0,"label_text":"Not-Related"}
+{"text":"These syndromes are often undiagnosed or misdiagnosed and lead to unnecessary morbidity and noncompliance with recommended pharmacotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Cholesterol-lowering agents have been demonstrated to decrease hepatic lipids in Niemann-Pick type C patients.","label":0,"label_text":"Not-Related"}
+{"text":"A case of mania associated with fluoxetine.","label":1,"label_text":"Related"}
+{"text":"The immunoassay's known cross-reactivity for carbamazepine is reportedly as low as 0.3%.","label":0,"label_text":"Not-Related"}
+{"text":"Both procedures were uncomplicated until about 30 min after reperfusion of the graft, when the cut surfaces began to ooze blood.","label":0,"label_text":"Not-Related"}
+{"text":"We will also discuss the clinical and pathophysiological considerations.","label":0,"label_text":"Not-Related"}
+{"text":"DISCUSSION: Electrolyte disorders associated with foscarnet are reviewed.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: Close monitoring for severe skin reactions is in order when using leflunomide.","label":0,"label_text":"Not-Related"}
+{"text":"These in vitro findings and clinical course suggest that TRAb\/TBII without thyroid-stimulating activity may develop in patients with amiodarone-induced destructive thyroiditis, as reported in patients with destructive thyroiditis, such as subacute and silent thyroiditis.","label":1,"label_text":"Related"}
+{"text":"We describe the case of a 61-year-old Peruvian man, who received bilateral lung transplants for idiopathic pulmonary fibrosis, and subsequently developed persistent fever with pulmonary infiltrates, ventilator dependence, and pneumothoraces.","label":0,"label_text":"Not-Related"}
+{"text":"We describe an 11-year-old girl who presented with widespread erythematous and pustular lesions being treated with topical corticosteroid.","label":0,"label_text":"Not-Related"}
+{"text":"The six patients who received mecamylamine only also significantly improved (Wilcoxon signed rank test, p < 0.2).","label":0,"label_text":"Not-Related"}
+{"text":"We report three cases of patients who developed leukopenia during olanzapine treatment.","label":1,"label_text":"Related"}
+{"text":"Arthritis and bursitis in multiple sclerosis patients treated with interferon-beta.","label":1,"label_text":"Related"}
+{"text":"Primary Central Nervous System Lymphoma (PCNSL) was seen in 2% of the liver, and 2% of the heart recipients.","label":0,"label_text":"Not-Related"}
+{"text":"Pulses were administered after the injection of 1% lidocaine solution around the treatment site.","label":0,"label_text":"Not-Related"}
+{"text":"Acute pleuropericarditis relevant to post-cardiac injury syndrome with an atypically early onset might have occurred in this case as a rare complication of PCI.","label":0,"label_text":"Not-Related"}
+{"text":"From 1996 to 2002 several medications were changed due to their adverse effects: indinavir (renal colic and fever), nelfinavir (cutaneous rash), and efavirenz (nausea and temporary memory loss).","label":1,"label_text":"Related"}
+{"text":"There was no loss of consciousness.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of chronic use of HCQ associated with torsade de pointes.","label":1,"label_text":"Related"}
+{"text":"Stroke-like syndrome after gold sodium thiomalate induced vasomotor reaction.","label":1,"label_text":"Related"}
+{"text":"Hematocrit was 20% (previously 33%).","label":0,"label_text":"Not-Related"}
+{"text":"It was hypothesized that valproic acid may interfere with glucuronidation of lamotrigine, leading to increased serum lamotrigine levels, or perhaps alter the drug's metabolism, resulting in accumulation of a toxic intermediate metabolite.","label":1,"label_text":"Related"}
+{"text":"In each patient, a different method successfully removed the touch of the anterior vitreous face to the corneal endothelium with subsequent prompt clearing of the corneal edema.","label":0,"label_text":"Not-Related"}
+{"text":"The concern about depression associated with beta-blocker use grew out of one widely referenced case report.","label":0,"label_text":"Not-Related"}
+{"text":"This case reveals that HPS could develop after alloBMT, even when engraftment of hematopoietic cells is not confirmed.","label":0,"label_text":"Not-Related"}
+{"text":"In addition, known and\/or possible mechanisms of the disorders are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"Six children with refractory acute lymphocytic leukemia were treated with vincristine combined with diltiazem.","label":0,"label_text":"Not-Related"}
+{"text":"The immunosuppressive regimen consisted of tacrolimus, mycophenolate mofetil, and prednisone.","label":0,"label_text":"Not-Related"}
+{"text":"PURPOSE: To evaluate the toxicity of 1 mg of intraocular rituximab and to present a small case-series of patients treated with intravitreal rituximab.","label":0,"label_text":"Not-Related"}
+{"text":"Post-transplant EBV-related lymphoproliferative disorder complicating umbilical cord blood transplantation in patients of adrenoleukodystrophy.","label":0,"label_text":"Not-Related"}
+{"text":"We hypothesized that VVR induced inflammation and adversely affected mucociliary function, and tested this hypothesis in an animal model of airway inflammation.","label":0,"label_text":"Not-Related"}
+{"text":"Type II heparin-induced thrombocytopenia (HIT) is an immunological disorder characterized by antibodies to heparin-platelet factor 4 complexes and a high risk of thrombotic complications.","label":1,"label_text":"Related"}
+{"text":"Toxic optic neuropathy associated with ethambutol: implications for current therapy.","label":1,"label_text":"Related"}
+{"text":"Median survival ranges from 15 to 24 months, and it appears that the disease cannot be cured.","label":0,"label_text":"Not-Related"}
+{"text":"We report a 4-year-old girl who presented with acute bilateral blindness, a focal seizure and hypertension 10 days after commencing oxybutynin to treat enuresis.","label":1,"label_text":"Related"}
+{"text":"Administration of lamotrigine, especially in combination with valproic acid, may lead to the development of TEN.","label":1,"label_text":"Related"}
+{"text":"We discuss the association between carbamazepine and hyponatremia and the causes of hyponatremia after cardiopulmonary bypass.","label":1,"label_text":"Related"}
+{"text":"Linear immunoglobulin A bullous dermatosis induced by gemcitabine.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: We conclude that a high dose combined with a short infusion time increases the risk of anaphylactoid reactions with the administration of intraperitoneal cisplatin.","label":1,"label_text":"Related"}
+{"text":"Catheter occlusion by calcium carbonate during simultaneous infusion of 5-FU and calcium folinate.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: A single intravitreal injection of triamcinolone induced clinical and angiographic resolution of inflammatory macular oedema in all patients for varying periods of time up to 6 months.","label":0,"label_text":"Not-Related"}
+{"text":"Astute observation, leading to the early detection of behavioral changes, may help avert the development of a costly and disabling complication of drug therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Despite drug withdrawal there was evidence of persistent airways obstruction and bronchial hyperreactivity.","label":0,"label_text":"Not-Related"}
+{"text":"Nonfatal prolonged overdosage of pyrimethamine in an infant: measurement of plasma and urine levels using HPLC with diode-array detection.","label":0,"label_text":"Not-Related"}
+{"text":"Unlike most reported cases in which vertebral compromise rarely extends to more than two adjacent vertebrae, our patient had extensive compromise of the thoracic spine.","label":0,"label_text":"Not-Related"}
+{"text":"Radiation recall with oxaliplatin: report of a case and a review of the literature.","label":0,"label_text":"Not-Related"}
+{"text":"The goal of this study is to describe three patients diagnosed with migraine and epilepsy (both under control) who evolved into status migrainosus after the introduction of oxcarbazepine (OXC), as part of a switch off from carbamazepine (CBZ).","label":1,"label_text":"Related"}
+{"text":"The patient subsequently developed progressive worsening of her vision and presented to our ED with bilateral visual loss.","label":0,"label_text":"Not-Related"}
+{"text":"Fatal intravascular autoimmune hemolytic anemia after fludarabine treatment for chronic lymphocytic leukemia.","label":1,"label_text":"Related"}
+{"text":"Lithium has been reported to raise serum calcium and lower serum phosphate concentrations and to increase urinary calcium excretion.","label":0,"label_text":"Not-Related"}
+{"text":"Corticosteroid therapy is a rare but possible independent predisposition to PCP.","label":0,"label_text":"Not-Related"}
+{"text":"Sertraline 50 mg\/day was again prescribed for the patient's persistent depressed mood.","label":0,"label_text":"Not-Related"}
+{"text":"This is a transient febrile illness that can occur in patients after the first adequate dose of an anti-microbial drug to treat infectious diseases such as syphilis, Lyme disease and relapsing fever.","label":0,"label_text":"Not-Related"}
+{"text":"Toxic streptococcal syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Stupor and fast activity have been related to the effects on gamma-aminobutyric acid type A (GABA(A)) receptors mediated by endozepines or by exogenous drugs such as benzodiazepines or barbiturates.","label":0,"label_text":"Not-Related"}
+{"text":"The primary outcome (behavioural disturbances) was measured prospectively by the Neuropsychiatric Inventory (NPI), while other outcomes included cognition (Mini-Mental State Examination (MMSE)) and Clinical Global Impression.","label":0,"label_text":"Not-Related"}
+{"text":"In this study, we report on three individual patients who received BTX-B and who subsequently developed parasympathetic dysfunction of the visual system after injections of BTX-B at remote sites.","label":1,"label_text":"Related"}
+{"text":"In all three patients the bleeding stopped after a course of aminocaproic acid was begun.","label":0,"label_text":"Not-Related"}
+{"text":"Antisocial behaviour was controlled in 12 out of the 13 behaviour-disordered group.","label":0,"label_text":"Not-Related"}
+{"text":"These findings suggest that GL might inhibit HIV-1 replication in vivo.","label":0,"label_text":"Not-Related"}
+{"text":"An extraordinarily rare case report of mixed fat redistribution syndrome associated with osteopenia but not with relevant metabolic abnormalities is documented in a prepubertal child with congenital HIV infection treated with antiretroviral therapy since the age of six months, up to the present age of 12 years and two months.","label":0,"label_text":"Not-Related"}
+{"text":"A male patient with malignant lymphoma and thyroid papillary carcinoma after pediatric renal transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"Minoxidil is a potent antihypertensive agent used in the treatment of resistant hypertension.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: Case series.","label":0,"label_text":"Not-Related"}
+{"text":"A short review on imatinib-related hepatotoxicity is also presented.","label":1,"label_text":"Related"}
+{"text":"A combination of these two approaches may provide the best chance of improving outcome in severe acute ischemic stroke.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of a 64-year-old man with secondary adrenocortical insufficiency who has been on a chronic transdermal fentanyl treatment because of sciatic pain syndrome.","label":1,"label_text":"Related"}
+{"text":"Visual hallucinations after intravitreal injection of bevacizumab in vascular age-related macular degeneration.","label":1,"label_text":"Related"}
+{"text":"Systemic disease, most commonly renal dysfunction, preceded all 30 reported cases of acyclovir neurotoxicity.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: Sexual side effects of fluoxetine may be more variable than previously thought.","label":0,"label_text":"Not-Related"}
+{"text":"Blood transfusions worsen the evolution of this peculiar form of HUS.","label":0,"label_text":"Not-Related"}
+{"text":"Cisplatin-induced syndrome of inappropriate antidiuretic hormone (SIADH) in a patient with neuroendocrine tumor of the cervix: a case report and review of the literature.","label":1,"label_text":"Related"}
+{"text":"Prior surgical ligation of the peribiliary arteries around the extrahepatic bile duct followed by TAE was considered to have played a crucial role in the development of ischemic cholangitis.","label":0,"label_text":"Not-Related"}
+{"text":"This case study is the second report of localized purpura after prolonged lamotrigine treatment suggesting this may be an atypical lamotrigine-induced drug reaction.","label":1,"label_text":"Related"}
+{"text":"A 69-year-old man developed pure red cell aplasia after taking fenoprofen for ten months.","label":1,"label_text":"Related"}
+{"text":"We report the case of a lung cancer patient with bronquiloalveolar carcinoma (BAC) presenting with BOOP after chemotherapy with docetaxel and gemcitabine producing severe respiratory insufficiency, and simulating a progression of the tumor.","label":1,"label_text":"Related"}
+{"text":"Pigmentary aberrations are well known side effects of cytostatic chemotherapeutic agents.","label":0,"label_text":"Not-Related"}
+{"text":"However, none were as severe as the first rash.","label":0,"label_text":"Not-Related"}
+{"text":"Maintenance tricyclic antidepressants induced rapid cycling between mania and depression in five female bipolar (manic-depressive) patients.","label":0,"label_text":"Not-Related"}
+{"text":"A 65-year-old woman, in the intensive care unit because of septic shock and acute renal failure, had a small-bowel obstruction due to Amphojel concretions.","label":1,"label_text":"Related"}
+{"text":"Prick tests and intradermal tests with a series of dilutions of carboplatin and cisplatin were performed on three patients who had exhibited medium and severe hypersensitivity reactions to carboplatin.","label":1,"label_text":"Related"}
+{"text":"Respiratory function tests were useful in the diagnosis of the interstitial abnormality and in monitoring response to prednisone.","label":0,"label_text":"Not-Related"}
+{"text":"Ziprasidone is an atypical antipsychotic drug that is believed to have a low propensity for inducing extrapyramidal symptoms, including tardive dyskinesia (TD).","label":1,"label_text":"Related"}
+{"text":"The reappearance of more virulent strains of exotoxin-producing streptococci over the past decade has led to the re-emergence of invasive Group A streptococcal infections and the recognition of a new syndrome resembling staphylococcal toxic shock syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Despite aggressive, combined antiviral treatment with ganciclovir and foscarnet and reduction of immunosuppression, viral clearance was never achieved.","label":0,"label_text":"Not-Related"}
+{"text":"It has only been described in 10 case reports since 1989.","label":0,"label_text":"Not-Related"}
+{"text":"Empirical therapy with antibiotics and conventional amphotericin B failed to resolve the infection.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of Stevens-Johnson syndrome\/toxic epidermal necrolysis (SJS\/TEN) secondary to trimethoprim-sulfamethoxazole (TMP-Sx) therapy for presumed community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND: Infection continues to be one of the major complications of cerebro-spinal fluid shunting procedures.","label":0,"label_text":"Not-Related"}
+{"text":"A retrospective review revealed that the patient had been exposed to iopamidol, an intravenous contrast medium, on the day prior to the commencement of methotrexate treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Metamizole use by Latino immigrants: a common and potentially harmful home remedy.","label":0,"label_text":"Not-Related"}
+{"text":"In the worst cases, these therapies are harmful.","label":0,"label_text":"Not-Related"}
+{"text":"Liver enzymes returned to normal 4 and 8 weeks, respectively, after riluzole withdrawal.","label":0,"label_text":"Not-Related"}
+{"text":"The cutaneous lesions resolved completely after 1 week of treatment with topical betamethasone dipropionate and gentamicin sulfate (twice daily).","label":0,"label_text":"Not-Related"}
+{"text":"The incidence of similar cases seems to increase.","label":0,"label_text":"Not-Related"}
+{"text":"Clinicians should include phenolphthalein in their list of possible causes of drug-induced TEN.","label":1,"label_text":"Related"}
+{"text":"We propose diagnostic criteria for this under-recognized new clinical syndrome, and recommend that physicians routinely measure serum gastrin levels in persistent cases of PPI-dependent dyspepsia unassociated with H. pylori.","label":0,"label_text":"Not-Related"}
+{"text":"Case report.","label":0,"label_text":"Not-Related"}
+{"text":"Two months after the start of the therapy, parathyroid hormone (PTH) decreased significantly and the skin lesions nearly disappeared.","label":0,"label_text":"Not-Related"}
+{"text":"(2) Chemotherapy induced host tissue reaction has not been extensively studied.","label":0,"label_text":"Not-Related"}
+{"text":"We present two cases in which both patients suffered with CLS, which we believe was caused following administration of granulocyte colony-stimulating factor, to our knowledge not described in the intensive care patient previously.","label":1,"label_text":"Related"}
+{"text":"We describe three testicular cancer patients who were cured with chemotherapy but developed bilateral osteonecrosis of the femoral head 17, 22 and 55 months after chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Knowledge of suspected cases will lead to early recognition and prompt management of this condition in the future.","label":0,"label_text":"Not-Related"}
+{"text":"They achieved a complete remission confirmed by light microscopy, but reverse transcriptase polymerase chain reaction remained positive after ATRA, underlining the need of further chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Increased awareness is needed on the possible occurrence of LPD resembling gastric cancer in rheumatoid arthritis patients treated with MTX.","label":1,"label_text":"Related"}
+{"text":"It is recommended that acid-fast stains be done on \"diphtheroids\" when such isolates are suspected pathogens.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was then treated with IL-2 1.8 x 10(6) U\/m2 for 5 days per week and 2.5 MU\/m2 IFN-alpha three times per week.","label":0,"label_text":"Not-Related"}
+{"text":"Disseminated Nocardia asteroides and coinfection with Trichophyton rubrum in a renal transplant recipient.","label":0,"label_text":"Not-Related"}
+{"text":"Less common adverse events to dapsone include the idiosyncratic reactions of leukopenia and agranulocytosis, cutaneous eruptions, peripheral neuropathy, psychosis, toxic hepatitis, cholestatic jaundice, nephrotic syndrome, renal papillary necrosis, severe hypoalbuminemia without proteinuria, an infectious mononucleosis-like syndrome, and minor neurological and gastrointestinal complaints.","label":1,"label_text":"Related"}
+{"text":"When the morning count of WBC began to fall, WBC count was repeated in the afternoons.","label":0,"label_text":"Not-Related"}
+{"text":"These infections may be life-threatening if appropriate therapy is not vigorously initiated.","label":0,"label_text":"Not-Related"}
+{"text":"Folinic acid rescue used routinely in psoriatic patients with known methotrexate \"sensitivity\".","label":0,"label_text":"Not-Related"}
+{"text":"A 57-year-old woman presented with a 3-week history of dysphagia for solids, 6 months after starting treatment with nifedipine.","label":1,"label_text":"Related"}
+{"text":"Torsade de pointes occuring due to a long QT interval is a rare but potentially fatal arrhythmia.","label":0,"label_text":"Not-Related"}
+{"text":"An association is reported between Reye syndrome and varicella zoster virus (VZV) infection in a 10-year-old boy who had serologic evidence of coinfection with VZV and influenza A H3N2, and exposure to salicylates.","label":0,"label_text":"Not-Related"}
+{"text":"He had been taking trimethoprim-sulfamethoxazole for approximately eight days when he revisited his family physician, complaining of headaches, dizziness, difficulty with speech, weakness, and itching on the trunk of his body and legs, where a maculopapular rash was noted.","label":1,"label_text":"Related"}
+{"text":"These cases were considered unusual in light of the short delay of their onset after initiation of immunosuppressive therapy and their fulminant course: 3 of these patients died of PCP occurring during the first month of treatment with prednisone.","label":1,"label_text":"Related"}
+{"text":"Clofazimine, previously used in the treatment of leprosy, is now used for treatment of Mycobacterium avium complex infection in patients with acquired immune deficiency syndrome, dermatologic disorders, and graft-versus-host disease.","label":0,"label_text":"Not-Related"}
+{"text":"This case seems to be one of the first descriptions of the clinical relevance of a CYP2D6 heterozygous genotype in a patient treated with antidepressant.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To report the occurrence of acute cytolytic hepatitis in a patient exposed to pulse itraconazole therapy for 24 weeks and provide a concise review of the literature on cases of itraconazole-induced hepatitis.","label":1,"label_text":"Related"}
+{"text":"We describe a patient with phenobarbital-induced hypersensitivity syndrome who revealed syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with limbic encephalitis during the course of the disease.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of medulloblastoma as a secondary malignancy in a patient treated for immature teratoma of the ovary (ITO).","label":0,"label_text":"Not-Related"}
+{"text":"After therapy for diabetic coma with insulin (containing the preservative cresol) and electrolyte solutions was started, the patient complained of increasing myalgia, developed a high fever and respiratory and metabolic acidosis and lost consciousness.","label":1,"label_text":"Related"}
+{"text":"At this point, she developed whole body urticaria and pruritus with edema of the extremities.","label":0,"label_text":"Not-Related"}
+{"text":"A 49-year-old man with Crohn's disease treated with prednisone and mesalamine (5-ASA) developed worsening respiratory distress and fever.","label":1,"label_text":"Related"}
+{"text":"A brief review of reported cases of chloramphenicol hypersensitivity in the English-language literature, as well as possible alternative explanations in this case, are provided.","label":1,"label_text":"Related"}
+{"text":"Thrombocytopenia, antithrombin deficiency and extensive thromboembolism in pregnancy: treatment with low-molecular-weight heparin.","label":0,"label_text":"Not-Related"}
+{"text":"The current report describes a man who was prescribed zonisamide for epilepsy and subsequently developed widespread skin rash, acute kidney injury, high-grade fever, eosinophilia, liver dysfunction, lymphadenopathy and an increase in antihuman herpesvirus-6 immunoglobulin G titer.","label":1,"label_text":"Related"}
+{"text":"We studied the hypothalamic-pituitary-adrenocortical axis in two female patients before and during treatment with CPH82.","label":0,"label_text":"Not-Related"}
+{"text":"Listeria monocytogenes peritonitis in a patient on continuous ambulatory peritoneal dialysis.","label":0,"label_text":"Not-Related"}
+{"text":"During a second FAB infusion (400 mg) the patient reverted to regular AV-conduction.","label":0,"label_text":"Not-Related"}
+{"text":"We describe two cases of acute pancreatitis that occurred after long term mesalamine therapy for ulcerative colitis.","label":1,"label_text":"Related"}
+{"text":"Generally, only a small proportion of prenatally exposed children are affected.","label":0,"label_text":"Not-Related"}
+{"text":"Five cases (four from the literature and one new case) are presented in which patients unsuspected of having vitamin B12 deficiency developed subacute combined degeneration of the spinal cord following nitrous oxide anesthesia.","label":1,"label_text":"Related"}
+{"text":"By contrast, corticosteroids inhibited the LAR but not the immediate response.","label":0,"label_text":"Not-Related"}
+{"text":"The leucopenia and thrombocytopenia resolved on the 7th and 13th days of hospitalization, respectively.","label":0,"label_text":"Not-Related"}
+{"text":"The delusion occurred in an agitated hypomanic state and was preceded by an intense pruritus.","label":0,"label_text":"Not-Related"}
+{"text":"Molecular analysis confirmed the vaccine strain as the causative agent.","label":0,"label_text":"Not-Related"}
+{"text":"Acute coronary artery occlusion during percutaneous transluminal coronary angioplasty: reopening by intracoronary streptokinase before emergency coronary artery surgery to prevent myocardial infarction.","label":0,"label_text":"Not-Related"}
+{"text":"Anti-tuberculous drugs had been stopped on the 2nd day of therapy due to development of optic neuritis secondary to ethambutol administration at another hospital.","label":1,"label_text":"Related"}
+{"text":"Pathology revealed the sarcoma adjacent to the recurrent ependymoma.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients with giant atrial thrombi whose treatment involved complications are presented.","label":0,"label_text":"Not-Related"}
+{"text":"Acute tumour lysis syndrome in a dog with B-Cell multicentric lymphoma.","label":0,"label_text":"Not-Related"}
+{"text":"Neuroleptic malignant syndrome (NMS) is a potentially fatal adverse reaction to psychopharmacologic treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Renal complications are uncommon and not well recognized.","label":0,"label_text":"Not-Related"}
+{"text":"To our knowledge, this is the first report of a bacterial corneal ulcer associated with use of a rigid gas-permeable contact lens on an extended-wear basis.","label":0,"label_text":"Not-Related"}
+{"text":"Eighty infants with proliferative retinopathy of prematurity (ROP) were treated with peripheral retinal cryoablation.","label":0,"label_text":"Not-Related"}
+{"text":"Beneficial effect of low-dose mianserin on fluvoxamine-induced akathisia in an obsessive-compulsive patient.","label":1,"label_text":"Related"}
+{"text":"Case history of an African woman presenting with advanced HIV and a painful conjunctival lesion is presented.","label":0,"label_text":"Not-Related"}
+{"text":"He was hospitalized for 51 days and, after aggressive diuresis and discontinuation of pioglitazone, was discharged with a weight loss of 30 pounds.","label":0,"label_text":"Not-Related"}
+{"text":"Neuroimaging shows bilateral subcortical and cortical edema with prominent posterior distribution.","label":0,"label_text":"Not-Related"}
+{"text":"Headache, nausea, emesis, and lethargy were the presenting signs.","label":0,"label_text":"Not-Related"}
+{"text":"Eur J Paediatr Neurol 2002;6(3):153-9.].","label":0,"label_text":"Not-Related"}
+{"text":"CASE SUMMARY: A 61-year old man with a history of sick sinus syndrome with persistent atrial fibrillation and infrequent premature ventricular contractions was admitted to the hospital for symptoms of amnesia and disorientation to time, place, and date.","label":0,"label_text":"Not-Related"}
+{"text":"Dyspnea possibly associated with controlled-release morphine sulfate tablets.","label":1,"label_text":"Related"}
+{"text":"The history is strongly suggestive of concurrent NMS.","label":0,"label_text":"Not-Related"}
+{"text":"He was initially treated with interferon alfa and subsequently relapsed within one year of treatment.","label":0,"label_text":"Not-Related"}
+{"text":"It has a considerably lower risk of cardiotoxicity than its parent compound, doxorubicin.","label":0,"label_text":"Not-Related"}
+{"text":"Quetiapine is a recently introduced atypical antipsychotic.","label":0,"label_text":"Not-Related"}
+{"text":"Carbamazepine is metabolized by this subsystem.","label":0,"label_text":"Not-Related"}
+{"text":"Rapamycin\/sirolimus (SR), trade named Rapammune (Wyeth-Ayerst, Sydney, Australia), is a potent immunosuppressive drug associated with myelosuppression, hypertension, hyperlipidemia, and infection.","label":1,"label_text":"Related"}
+{"text":"The autopsy findings revealed massive Strongyloidiasis with the presence of larvae in several organs, particularly in the intestinal wall, the lungs and the liver.","label":0,"label_text":"Not-Related"}
+{"text":"Five and one-half years after the diagnosis of myeloma, while in remission on cyclophosphamide therapy, the patient experienced severe abdominal right lower quadrant pain due to a large cecal lymphoma.","label":1,"label_text":"Related"}
+{"text":"METHODS: Case series consisting of 3 patients treated with rifabutin were retrospectively studied.","label":0,"label_text":"Not-Related"}
+{"text":"Diphenhydramine is generally considered an innocuous drug with a minimal risk for abuse and untoward side effects.","label":0,"label_text":"Not-Related"}
+{"text":"Various hypotheses as to the complex actions of morphine and its antagonist in epileptogenesis are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"Linezolid-associated acute interstitial nephritis and drug rash with eosinophilia and systemic symptoms (DRESS) syndrome.","label":1,"label_text":"Related"}
+{"text":"Each of these was subsequently reviewed by the hematologist who treated the patients for AML.","label":0,"label_text":"Not-Related"}
+{"text":"Blood gas analysis revealed a respiratory acidosis.","label":0,"label_text":"Not-Related"}
+{"text":"Compared with anthracyclines and taxanes, the interval from the completion of radiation therapy to the initiation of chemotherapy is less for gemcitabine (median time of 56 days for gemcitabine, compared with 218 days for the taxanes and 646 days for doxorubicin).","label":0,"label_text":"Not-Related"}
+{"text":"The suggested treatment algorithm allows for specific treatment of both disorders and avoids potentially exacerbating either one.","label":0,"label_text":"Not-Related"}
+{"text":"Scleritis complicating zoledronic acid infusion.","label":1,"label_text":"Related"}
+{"text":"A case is reported in which treatment was given on postnatal day 3.","label":0,"label_text":"Not-Related"}
+{"text":"'Maqianzi' (the dried ripe seed of Strychnos nux-vomica L.) contains 1.0-1.4% each of strychnine and brucine.","label":0,"label_text":"Not-Related"}
+{"text":"Ampicillin may aggravate clinical and experimental myasthenia gravis.","label":1,"label_text":"Related"}
+{"text":"In rare cases mitomycin C (MMC) may induce cancer-associated hemolytic uremic syndrome, which is characterized by hemolytic anemia, thrombocytopenia and progressive renal failure.","label":1,"label_text":"Related"}
+{"text":"The median time to progression was 3.9 months and the median overall survival time was 11.6 months.","label":0,"label_text":"Not-Related"}
+{"text":"No relapse of pneumonia was observed after a 4-month follow-up.","label":0,"label_text":"Not-Related"}
+{"text":"There are no generally accepted therapeutic regimens for the treatment of fungal peritonitis in patients with continuous ambulatory peritoneal dialysis (CAPD).","label":0,"label_text":"Not-Related"}
+{"text":"A retrospective review incriminated transfusion therapy and volume overload as the etiology.","label":0,"label_text":"Not-Related"}
+{"text":"A severe form of Erythema multiforme (EM), diagnosed as Stevens-Johnson syndrome (SJS) was detected in a 10-year-old Indian male child who took herbal medication of plant origin prescribed by a traditional healer for remission of his fever.","label":0,"label_text":"Not-Related"}
+{"text":"However, a large case-control study included three cases of either Stevens-Johnson syndrome or toxic epidermal necrolysis associated with ofloxacin use, but no details of the cases were given.","label":1,"label_text":"Related"}
+{"text":"Rational combinations of preventive medications may also be useful.","label":0,"label_text":"Not-Related"}
+{"text":"The authors postulate that two types of combined lithium-neuroleptic toxicity occur: a neuroleptic malignant extrapyramidal syndrome and a lithium toxicity that occurs in combination with phenothiazines, primarily thioridazine.","label":1,"label_text":"Related"}
+{"text":"Fluoxetine-induced akathisia: clinical and theoretical implications.","label":1,"label_text":"Related"}
+{"text":"Infection with Mycobacterium genavense in a patient with systemic lupus erythematosus.","label":0,"label_text":"Not-Related"}
+{"text":"Second, we report a case of neutropenia, which proved to be fatal in a schizophrenia patient receiving olanzapine and thiazide.","label":1,"label_text":"Related"}
+{"text":"Priapism associated with zuclopenthixol.","label":1,"label_text":"Related"}
+{"text":"Controlled studies are necessary to assess the efficacy, the duration of therapy required for effective results, and the safety of this treatment over the long-term.","label":0,"label_text":"Not-Related"}
+{"text":"A fifth child manifested clinical and radiographic signs of rickets after presenting with hypophosphatemia, hypouricemia, and glycosuria.","label":0,"label_text":"Not-Related"}
+{"text":"We suggest that sarcoidosis may develop in chronic hepatitis C patients during interferon alpha and\/or ribavirin treatment, and diagnostic tests for this adverse effect should be performed during the follow-ups.","label":1,"label_text":"Related"}
+{"text":"We report the case of a patient who developed polyserositis (pericardial effusion, pleural effusion, and pericarditis) after being started on clozapine, and whose symptoms remitted upon discontinuation of clozapine.","label":1,"label_text":"Related"}
+{"text":"Quetiapine and obsessive-compulsive symptoms (OCS): case report and review of atypical antipsychotic-induced OCS.","label":1,"label_text":"Related"}
+{"text":"The possible deleterious effects of praziquantel therapy should be considered in the treatment of patients with subarachnoid cysticerci.","label":0,"label_text":"Not-Related"}
+{"text":"Here we reported the case of a liver transplant recipient with de novo HBV infection who had a favorable outcome after lamivudine (LAM) and adefovir dipivoxil (ADV) antiviral therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Only one report links phenylpropanolamine consumption to an intracerebral hemorrhage in a patient with an AVM.","label":1,"label_text":"Related"}
+{"text":"Strategies to prevent hyponatremia in children during urological procedures, with emphasis on the importance of reserving free water as the irrigation fluid are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"SUMMARY OF BACKGROUND DATA: Spinal pain, caused by an infective mass, developed in a 39-year-old man 3 months after an epidural injection for low back pain.","label":0,"label_text":"Not-Related"}
+{"text":"This patient received chemotherapy (mitomycin C, 5-fluoruracil, and cisplatin) and reached a good partial response.","label":0,"label_text":"Not-Related"}
+{"text":"The prosthesis may be responsible for blood seeding infection and not only a mere victim.","label":0,"label_text":"Not-Related"}
+{"text":"The immunosuppressive effect of intensive polychemotherapy may play a significant role in accelerating the malignant transformation.","label":0,"label_text":"Not-Related"}
+{"text":"This report suggests that anemia can occur due to MMF, in particular when it is given with prednisone, a side effect well documented in the transplantation literature when the triple combination of MMF, cyclosporine and prednisone is used.","label":1,"label_text":"Related"}
+{"text":"The low ionized calcium was unsuccessfully treated with several doses of calcium levulinate but successfully treated with 1 alpha-hydroxycholecalciferol.","label":0,"label_text":"Not-Related"}
+{"text":"Clioquinol intoxication occurring in the treatment of acrodermatitis enteropathica with reference to SMON outside of Japan.","label":0,"label_text":"Not-Related"}
+{"text":"We wish to call for cautious approach at time of cessation of prolonged ACTH therapy because of possible unexpected and only partially understood hazardous side effects such as hyperkalemia.","label":1,"label_text":"Related"}
+{"text":"A 16-year-old girl with erosive, polyarticular JRA showed no detectable change in her articular disease following nine exchanges.","label":0,"label_text":"Not-Related"}
+{"text":"Twenty-three patients who experienced HCMV antigenaemia or DNAemia during or at the end of prophylaxis were included.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of a 23-year-old man who developed a vancomycin-induced anaphylactic reaction in the treatment of methicillin-resistant Staphylococcus aureus infection.","label":1,"label_text":"Related"}
+{"text":"Accordingly, camptocormia is a dose-dependent side effect of valproate.","label":1,"label_text":"Related"}
+{"text":"The cure rate of this disease has been reported to be lower than for non-drug resistant TB, and the use of new experimental drugs in combination therapy is warranted.","label":0,"label_text":"Not-Related"}
+{"text":"Shortly after this treatment was initiated, the mare appeared comfortable and no longer had signs of pain.","label":0,"label_text":"Not-Related"}
+{"text":"We study three such patients who successfully converted to mycophenolate mofetil, and briefly examine the evidence behind this option.","label":0,"label_text":"Not-Related"}
+{"text":"The rash progressed to TEN in 7 days, and she was transferred to a burn treatment center.","label":0,"label_text":"Not-Related"}
+{"text":"Fungal infections involving the pacemaker pocket after pacemaker implantation procedure are extremely rare.","label":0,"label_text":"Not-Related"}
+{"text":"Severe dapsone hypersensitivity syndrome.","label":1,"label_text":"Related"}
+{"text":"A 36-year-old man being treated with cisplatinum, vinblastine, and bleomycin for testicular carcinoma developed a dense left homonymous hemianopsia, encephalopathy, and a partial nondominant parietal lobe syndrome.","label":1,"label_text":"Related"}
+{"text":"Transvaginal ultrasonography is a very sensitive test and therefore is often performed as a first-line screening test.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a patient with a liver abscess due to Entamoeba histolytica, in whom metronidazole therapy (total dose, 21 g over 14 days) was complicated by reversible deafness, tinnitus, and ataxia and who relapsed 5 months later with a splenic abscess.","label":1,"label_text":"Related"}
+{"text":"Giant right atrial thrombi treated with thrombolysis.","label":0,"label_text":"Not-Related"}
+{"text":"Transluminal removal of a fractured and embolized indwelling central venous catheter in the pulmonary artery.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was initially treated for presumed bacterial peritonitis but remained febrile and had persistent abdominal pain and peritoneal fluid pleocytosis, despite broad-spectrum antibiotic therapy.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: Atovaquone should be added to the list of agents causing vortex keratopathy involving the corneal epithelium.","label":1,"label_text":"Related"}
+{"text":"After drainage of the effusion she received combination chemotherapy with CDDP and VDS.","label":0,"label_text":"Not-Related"}
+{"text":"One child was briefly treated with imipramine, with similar results.","label":0,"label_text":"Not-Related"}
+{"text":"Unintentional ingestion of bupropion in young children has generally resulted in limited toxicity.","label":0,"label_text":"Not-Related"}
+{"text":"On the basis of these findings, a therapeutic approach to patients with drug-induced psychosis in PD is suggested.","label":0,"label_text":"Not-Related"}
+{"text":"Ocular ethambutol toxicity.","label":1,"label_text":"Related"}
+{"text":"Infliximab is a chimeric tumor necrosis factor-alpha (TNF-alpha) monoclonal antibody, which has been used extensively in patients with rheumatoid arthritis and inflammatory bowel disease.","label":0,"label_text":"Not-Related"}
+{"text":"Laboratory tests excluded any underlying condition.","label":0,"label_text":"Not-Related"}
+{"text":"All three patients had previously experienced good responses to sumatriptan or zolmitriptan, but were limited in frequency of use by the authors.","label":0,"label_text":"Not-Related"}
+{"text":"Ten months prior to TAE the patient had undergone central bisegmentectomy for hepatocellular carcinoma with resection of the extrahepatic bile duct.","label":0,"label_text":"Not-Related"}
+{"text":"The patient required s.c. epinephrine and i.v. diphenhydramine, methylprednisolone, and ranitidine.","label":0,"label_text":"Not-Related"}
+{"text":"A 79-year-old man with ischemic heart disease, chronic atrial fibrillation, chronic renal failure, hypothyroidism, and gout arthritis was hospitalized because of fatigue, myalgia, and leg weakness, shortly after starting treatment with colchicine.","label":1,"label_text":"Related"}
+{"text":"We also report a sixth case, involving an adult with an intramuscular coenurus.","label":0,"label_text":"Not-Related"}
+{"text":"It has many known toxicities and has been reported to cause anaphylaxis.","label":0,"label_text":"Not-Related"}
+{"text":"Possible reasons and clinical significance of this complication are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"Subconjunctival and external hemorrhage secondary to oral anticoagulation.","label":0,"label_text":"Not-Related"}
+{"text":"Bronchoalveolar lavage (BAL) revealed lymphocyte alveolitis with a low CD4\/CD8 ratio (0.36), consistent with an immunoallergic phenomenon, rather than the most often evoked toxic hypothesis.","label":0,"label_text":"Not-Related"}
+{"text":"The results of our investigation were inconclusive, but suggested that the endoscope could have been responsible for some of the cases.","label":0,"label_text":"Not-Related"}
+{"text":"Several alternatives presently exist for patients considering surgical rhinoplasty.","label":0,"label_text":"Not-Related"}
+{"text":"Nevertheless, the symptoms often go unrecognized and patients remain undiagnosed for years, not receiving the highly efficacious colchicine therapy; their histories often include multiple laparotomies, laparoscopies, and psychiatric evaluations.","label":0,"label_text":"Not-Related"}
+{"text":"During his hospitalization he experienced bloodstream infections including fungemia due to Trichosporon mucoides and prolonged undulating fever despite antifungal and antibacterial treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Etanercept was stopped, and CD responded well to standard treatment.","label":0,"label_text":"Not-Related"}
+{"text":"The 171 patients were treated for a total of 4005 months, giving an incidence for severe infection of 3.30\/100 patient-years (95% CI 1.65-5.90).","label":0,"label_text":"Not-Related"}
+{"text":"Nineteen cases of unusual enhanced vincristine neurotoxicity related to itraconazole have been reported in children.","label":1,"label_text":"Related"}
+{"text":"The use of modern multiagent therapy often makes it difficult to appropriately apportion blame for causation of specific side effects.","label":0,"label_text":"Not-Related"}
+{"text":"At the end of each vitrectomy, 0.4 mg of gentamicin, 1.0 mg of cefazolin, and 0.32 mg of dexamethasone were injected into the vitreous cavity.","label":0,"label_text":"Not-Related"}
+{"text":"In both cases the etiology of the renal failure was not a direct result of the use of lithium.","label":0,"label_text":"Not-Related"}
+{"text":"Amphotericin B (AmB) is effective, but its use is limited by toxicity: renal impairment, anaemia, fever, malaise, and hypokalaemia are common.","label":1,"label_text":"Related"}
+{"text":"Iatrogenic endometrial megapolyps in women with breast carcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"She then was restabilized with warfarin.","label":0,"label_text":"Not-Related"}
+{"text":"Glutamine-supplemented tube feedings versus total parenteral nutrition in children receiving intensive chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Antiretroviral drugs may offer a better alternative to disfiguring surgery in the future.","label":0,"label_text":"Not-Related"}
+{"text":"Pseudomonas aeruginosa was the most common isolate and caused both CVC-related and CVC-unrelated infections, whereas other Pseudomonas spp. and Xanthomonas maltophilia were almost exclusively associated with CVC-related infections.","label":0,"label_text":"Not-Related"}
+{"text":"Cardiopulmonary resuscitation was successful after 45 minutes.","label":0,"label_text":"Not-Related"}
+{"text":"Bucillamine is used as an antirheumatic drug that is structurally analogous to D-penicillamine.","label":0,"label_text":"Not-Related"}
+{"text":"Positive inotropic support is routinely used for weaning from cardiopulmonary bypass circulation in patients with reduced left ventricular function.","label":0,"label_text":"Not-Related"}
+{"text":"Attempted treatment of factor H deficiency by liver transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"The case history of an 11-year-old boy is reported.","label":0,"label_text":"Not-Related"}
+{"text":"Laboratory work-up was unrevealing.","label":0,"label_text":"Not-Related"}
+{"text":"While not proving safety, these data add to previous smaller series with similar findings, thus lending tenuous support to the use of this agent.","label":0,"label_text":"Not-Related"}
+{"text":"We recommend that a TMA in association with quinine be consistently referred to as quinine-associated thrombotic microangiopathy (quinine-TMA) to better distinguish this entity from idiopathic TTP.","label":1,"label_text":"Related"}
+{"text":"One patient had a lower average heart rate and two patients had lower average mean blood pressure values during propranolol treatment, none of which was clinically significant.","label":1,"label_text":"Related"}
+{"text":"Mycobacterium fortuitum is a rare cause of central nervous system infection; however, shunt infection caused by this organism has not been reported.","label":0,"label_text":"Not-Related"}
+{"text":"We conclude that etanercept may be a safe and effective therapy not only in severe psoriatic arthritis, but also in cases of pustular rebound after withdrawal of immunosuppressive agents.","label":0,"label_text":"Not-Related"}
+{"text":"Lithium treatment of a patient with periodic catatonia.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: This case series describes a clinically distinct form of interface inflammation that presents late and is associated with elevated intraocular pressure.","label":0,"label_text":"Not-Related"}
+{"text":"Given this case report, we recommend close monitoring of women using this herbal preparation.","label":0,"label_text":"Not-Related"}
+{"text":"Pathophysiologic concerns have also been a key reason why physicians have avoided using beta-blockers in patients with diabetes.","label":0,"label_text":"Not-Related"}
+{"text":"Autopsy revealed diffuse vasculitis involving the heart, lungs, kidneys, testes, spleen, liver, skin, gut wall and marrow with neuritis of gut wall nerves and ganglia.","label":0,"label_text":"Not-Related"}
+{"text":"During her third cycle, she again received cisplatin 100 mg\/m2 over 30 minutes and developed palmar pruritus, urticaria, and edema.","label":1,"label_text":"Related"}
+{"text":"For the most part these preparations have been considered safe.","label":0,"label_text":"Not-Related"}
+{"text":"Destructive thyrotoxicosis appeared 4-6 months after starting IFN-alpha, followed by Graves' hyperthyroidism within 8 to 11 months.","label":1,"label_text":"Related"}
+{"text":"The incidence of 5-fluorouracil (5-FU)-related cardiotoxicity seems to be dosage and schedule dependent.","label":1,"label_text":"Related"}
+{"text":"Depressive symptoms got worse and electroconvulsive therapy was tried.","label":0,"label_text":"Not-Related"}
+{"text":"Again, a similar set of symptoms as seen initially were noted, along with an elevation of the serum CPK level.","label":0,"label_text":"Not-Related"}
+{"text":"She was apparently well after drinking the first of two bowls of 'maqianzi' decoction.","label":0,"label_text":"Not-Related"}
+{"text":"Nocardiosis. A literature review with selected case reports in two dogs.","label":0,"label_text":"Not-Related"}
+{"text":"Left main coronary artery stenosis treatment with two paclitaxel-eluting stents in a patient with cardiac allograft vasculopathy.","label":0,"label_text":"Not-Related"}
+{"text":"Electron microscopy showed diffuse effacement of the glomerular epithelial foot processes, leading to a diagnosis of minimal change nephrotic syndrome with interstitial nephritis.","label":0,"label_text":"Not-Related"}
+{"text":"Although various manifestations of pentamidine-induced cardiotoxicity have been reported, to our knowledge, second-degree heart block associated with this agent has not been described.","label":1,"label_text":"Related"}
+{"text":"Hysteria scores on the MMPI were found to be related significantly to self-reported effects under both the drug and placebo conditions.","label":0,"label_text":"Not-Related"}
+{"text":"Neutropenic enterocolitis should be considered in patients with abdominal symptoms especially during the granulocyte nadir following chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Physicians should keep in mind that taxanes such as paclitaxel have the potential to cause pneumonitis and lung fibrosis.","label":1,"label_text":"Related"}
+{"text":"Severe leukopenia associated with mild hepatotoxicity in an HIV carrier treated with nevirapine.","label":1,"label_text":"Related"}
+{"text":"After the patient developed recurrent infections, laboratory findings disclosed panhypogammaglobulinaemia with B-lymphocyte deficiency.","label":0,"label_text":"Not-Related"}
+{"text":"The effects of these drugs on the dentition such as tooth decay and erosion have been a subject of debate among dental practitioners.","label":0,"label_text":"Not-Related"}
+{"text":"By light and electron microscopic appearances the renal lesion was an epimembranous deposit form of membranous glomerulopathy.","label":0,"label_text":"Not-Related"}
+{"text":"We report the occurrence of delayed postoperative coma in five of nine consecutive children following surgery for insertion of baclofen infusion pumps.","label":0,"label_text":"Not-Related"}
+{"text":"A 34-year-old male with lumbar disc disease and surgery was placed on gabapentin daily for chronic back pain.","label":0,"label_text":"Not-Related"}
+{"text":"On further investigation, coronary angiography revealed a long chronic dissection of the right coronary artery.","label":0,"label_text":"Not-Related"}
+{"text":"She underwent a standard protocol for insulin desensitization twice in a 2-month period, with persistence in her symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"Ketorolac in reflex sympathetic dystrophy.","label":0,"label_text":"Not-Related"}
+{"text":"In a 61-year-old man receiving chronic low-dosage amiodarone an interstitial pneumopathy was observed.","label":1,"label_text":"Related"}
+{"text":"Infection of a shunt by Mycobacterium fortuitum: case report.","label":0,"label_text":"Not-Related"}
+{"text":"An unusual presentation of spontaneous sub-conjunctival haematoma in a patient receiving warfarin.","label":1,"label_text":"Related"}
+{"text":"The patients' median age was 21.5 years (range 16 to 53 years) with a median SAPS II of 14 (range 12 to 84) and an APACHE II of 8 (range 6 to 36).","label":0,"label_text":"Not-Related"}
+{"text":"Its treatment is mainly based upon discontinuation of heparin therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Both patients presented as self-referrals to the emergency department.","label":0,"label_text":"Not-Related"}
+{"text":"The two cases occurred on days 2 and 3 post-BMT, respectively.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was then submitted to three sections of 1,600 mg\/m2 of gemcitabine with intervals of 1 week.","label":0,"label_text":"Not-Related"}
+{"text":"The aim of this study is to evaluate steroid therapy effect in patient treated for eosinophilic jejunitis to share our experience with other colleagues.","label":0,"label_text":"Not-Related"}
+{"text":"The serumcholinesterase activity of the patient's serum increased by 55% (from 15% to 70%) following the injection.","label":0,"label_text":"Not-Related"}
+{"text":"Cicatricial entropion associated with chronic dipivefrin application.","label":1,"label_text":"Related"}
+{"text":"In 1984, a 56-year-old house painter developed intractable pain in his back and other joints.","label":0,"label_text":"Not-Related"}
+{"text":"This illustrates intravenous pamidronate as a valuable therapeutic tool when milk-alkali syndrome presents as hypercalcemic emergency.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a patient who developed HUS after treatment with mitomycin C (total dose 144 mg\/m2) due to a carcinoma of the ascending colon.","label":1,"label_text":"Related"}
+{"text":"Thrombosis of the left main coronary artery following percutaneous transluminal coronary angioplasty.","label":0,"label_text":"Not-Related"}
+{"text":"This was accepted as evidence for propranolol being the cause of this conduction disorder.","label":1,"label_text":"Related"}
+{"text":"The disease is suggested endoscopically by its typical appearance.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Headaches have been reported as a potential side effect of capecitabine therapy.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: Adrenal suppression after steroid injection for periocular capillary hemangioma is a potentially life-threatening complication.","label":0,"label_text":"Not-Related"}
+{"text":"She had just finished a 3-week course of intravenous tobramycin for bronchiectasis and had an elevated serum tobramycin trough level 1 week before the onset of tetany.","label":1,"label_text":"Related"}
+{"text":"Stenoses in the left coronary artery were verified angiographically.","label":0,"label_text":"Not-Related"}
+{"text":"This is one of the few cases of drug-induced LAD in which the target antigen profile has been characterized, and the first in which the antigen has been shown to correspond to collagen VII.","label":0,"label_text":"Not-Related"}
+{"text":"Despite discontinuance of the drug and\/or institution of corticosteroid therapy, progressive respiratory failure led to death.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of Parkinson's disease should be determined by level of disability and handicap.","label":0,"label_text":"Not-Related"}
+{"text":"The present report suggests that clarithromycin coadministration induces increased plasma carbamazepine concentrations, which may result in carbamazepine toxicity.","label":1,"label_text":"Related"}
+{"text":"Overall, the features are protean and may masquerade many other forms of toxaemias.","label":0,"label_text":"Not-Related"}
+{"text":"Sudden onset of erythroderma gave rise to a temporary arrest of the function of nail matrix with the resultant Beau's lines.","label":0,"label_text":"Not-Related"}
+{"text":"We report two cases of secondary AML in which platinum compounds were the sole prior chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"However, this reversible, probably drug-induced case of hypogammaglobulinaemia highlights the need for immunoglobulin measurements when immunodeficiency is suspected in lupus patients.","label":0,"label_text":"Not-Related"}
+{"text":"After a second dose of metoclopramide, these symptoms recurred and were associated with confusion, agitation, fever, diaphoresis, tachypnea, tachycardia, and hypertension.","label":1,"label_text":"Related"}
+{"text":"Muscle biopsy revealed fibrous myopathy.","label":0,"label_text":"Not-Related"}
+{"text":"Calciphylaxis is a rare, life-threatening cause of skin necrosis.","label":0,"label_text":"Not-Related"}
+{"text":"After immediate treatment with low molecular weight heparin (enoxaparin), the thrombus improved without any additional complications.","label":0,"label_text":"Not-Related"}
+{"text":"We describe t(8;16)(p11;p13) acute myeloid leukaemia (AML-M4) in a 12-year-old white male with a history of prenatal X-ray exposure.","label":0,"label_text":"Not-Related"}
+{"text":"Based on plasma TCA concentrations in our patient, we calculated a terminal half-life of TCA of 33 days as opposed to 5 days observed after intra-articular administration of a therapeutic dose of 40 mg TCA.","label":0,"label_text":"Not-Related"}
+{"text":"Excessive bleeding is a major concern during the administration of thrombolytic therapy.","label":0,"label_text":"Not-Related"}
+{"text":"The clinical response was reflected by an increase in circulating interleukin (IL) 10 and a decrease in IL-6 and IL-8 serum levels during treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Past medical history was significant for hepatitis C and bipolar disorder.","label":0,"label_text":"Not-Related"}
+{"text":"In two of the cases, the patients had documented histories of vascular disease, which their internists had identified as the cause of their impotence.","label":0,"label_text":"Not-Related"}
+{"text":"The next day, he suffered from a paralytic ileus.","label":0,"label_text":"Not-Related"}
+{"text":"Atypical CD8+ cutaneous T-cell lymphoma after immunomodulatory therapy.","label":0,"label_text":"Not-Related"}
+{"text":"The KS cases associated with glomerulonephritis are also reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"In a postoperative patient with pre-existent myasthenia gravis, oral verapamil caused a marked exacerbation in myasthenic weakness.","label":1,"label_text":"Related"}
+{"text":"However, in ill and\/or young children, behavioral audiometry may not be sufficiently precise to detect the early stages of hearing loss.","label":0,"label_text":"Not-Related"}
+{"text":"A 14-year-old female developed systemic lupus erythematosus (SLE)-like symptoms, rash, fever, leukopenia and positive anti-nuclear antibody (ANA) two weeks after administration of carbamazepine (CBZ; Tegretol) used against benign Rolandic epilepsy.","label":1,"label_text":"Related"}
+{"text":"Patients who have received total parenteral nutrition (TPN) without proper replacement of thiamine have also developed WE.","label":0,"label_text":"Not-Related"}
+{"text":"This article discusses the initial treatment attempted at resolving the bronchospasm, as well as the use of heliox in the ultimate resolution of the bronchospasm.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of acute generalized exanthematous pustulosis (AGEP) in a 50-year-old woman that was attributed to the ingestion of nimesulide.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND: Hypersensitivity reactions to cyclosporine are rare.","label":1,"label_text":"Related"}
+{"text":"A 78-year-old woman with many medical problems, including chronic obstructive pulmonary disease, was treated with parenteral levofloxacin for community-acquired pneumonia.","label":0,"label_text":"Not-Related"}
+{"text":"In a female with acute lymphoblastic leukemia, inadvertent doxorubicin administration intrathecally caused severe, life-threatening, acute encephalopathy with high-pressure hydrocephalus.","label":1,"label_text":"Related"}
+{"text":"Regardless of a negative history of asthma, therefore, life-threatening bronchospasm must be considered a possible complication of propranolol therapy.","label":1,"label_text":"Related"}
+{"text":"An acquired form of sideroblastic anemia has been described in association with several drugs, especially anti-microbial agents.","label":0,"label_text":"Not-Related"}
+{"text":"The role of Adriamycin in the production of cardiotoxicity is reviewed.","label":1,"label_text":"Related"}
+{"text":"DISCUSSION: Back pain, with or without opioid dependence, is commonly encountered in general practice.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment brought about a decrease in the extent and depth of osteoid, but matrix abnormalities remained.","label":0,"label_text":"Not-Related"}
+{"text":"This regimen was well tolerated, although both children were critically ill.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: ECT with muscle relaxants could be administered safely, with appropriate precautions kept in mind.","label":0,"label_text":"Not-Related"}
+{"text":"Erosive oral lichen planus (OLP) is a painful chronic inflammatory disease that is sometimes resistant to systemic or topical therapies.","label":0,"label_text":"Not-Related"}
+{"text":"The patient had insertion of the levonorgestrel-releasing intrauterine system (LNG-IUS).","label":0,"label_text":"Not-Related"}
+{"text":"After irradiation of only the right eye, the rats were followed for several months in an attempt to determine the effects of estrogen on radiation cataractogenesis and investigate potential strain differences in this phenomenon.","label":0,"label_text":"Not-Related"}
+{"text":"A CT scan revealed an abdominopelvic abscess encompassing the detached catheter which embedded in the rectosigmoid colon, allowing direct communication to the upper vagina.","label":0,"label_text":"Not-Related"}
+{"text":"There was one reported death.","label":0,"label_text":"Not-Related"}
+{"text":"Biopsy specimens of the upper tarsal conjunctiva in soft contact lens-associated giant papillary conjunctivitis were taken during (1) chronic exacerbation, (2) brief remission, and (3) intentional exacerbation.","label":0,"label_text":"Not-Related"}
+{"text":"He developed hypertension in April 1989, underwent a final chelation, and retired.","label":0,"label_text":"Not-Related"}
+{"text":"Recurrent prosthetic hip infections, particularly in immunosuppressive patients, should alert the physician to consider the possibility of both tuberculous and atypical mycobacterial infections.","label":0,"label_text":"Not-Related"}
+{"text":"Progressive paraplegia, one of the devastating neurologic complications related to this mode of treatment, has been attributed to spinal cord toxicity.","label":0,"label_text":"Not-Related"}
+{"text":"Although there was evidence of spread of the S typhimurium in the community, there was no evidence of spread of this Salmonella R plasmid to the normal flora of patients or their family members a median of 14 weeks after the infection.","label":0,"label_text":"Not-Related"}
+{"text":"He had previously received both local tumor bed and craniospinal radiation therapy together with intensive myeloablative alkylator chemotherapy before autologous stem cell rescue.","label":0,"label_text":"Not-Related"}
+{"text":"Interestingly, the majority of cases after OHSS involve thrombosis of the upper extremities.","label":0,"label_text":"Not-Related"}
+{"text":"We report on a case of localized ganglioneuroblastoma treated by carboplatin\/etoposide for 2 courses and surgery, which developed a serious GHD after 56 months.","label":0,"label_text":"Not-Related"}
+{"text":"During that time, he had also been taking amphetamine-dextroamphetamine (Adderall) on work days for his ADHD.","label":0,"label_text":"Not-Related"}
+{"text":"We present the case of a 52-year-old white male who showed arthritis, conjunctivitis and non-gonococcal urethritis.","label":0,"label_text":"Not-Related"}
+{"text":"After 14 days of anticoagulant therapy with UFH, the regimen was changed to low molecular weight heparin (LMWH; Fraxiparin 0.3; 2850 IU anti-X activity\/d s.c.; bw 60 kg).","label":0,"label_text":"Not-Related"}
+{"text":"He was hyperthermic (oral temperature 40.6 degrees C), diaphoretic, tachycardic (heart rate 140 beats\/min), and tachypneic (respiratory rate 22 breaths\/min), with severe muscle rigidity and shaking tremors.","label":0,"label_text":"Not-Related"}
+{"text":"Toxic symptoms (sinus arrest) reappeared twice and were accompanied by increasing amounts of non-antibody-bound DGTX in the serum.","label":0,"label_text":"Not-Related"}
+{"text":"We followed bone marrow morphology in a 2-year-old male with HS who received up to 8 micrograms\/kg GM-CSF per day because of failure of allogeneic bone marrow engraftment.","label":0,"label_text":"Not-Related"}
+{"text":"Shortly after chemotherapy and an injection of pegfilgrastim, the patient developed poorly defined, rapidly progressive erythema, edema, and pain in his right forearm.","label":1,"label_text":"Related"}
+{"text":"Elective surgery days after myocardial infarction: clinical and ethical considerations.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: We believe this observed rate of serious infection is acceptable in the context of optimally treating active RA.","label":0,"label_text":"Not-Related"}
+{"text":"The intralesional injection of corticosteroids has been employed successfully in treatment of adnexal neonatal hemangiomas since 1979.","label":0,"label_text":"Not-Related"}
+{"text":"The latter form (Macrodantin) is reported to engender less gastrointestinal intolerance but it can produce the same adverse effects as the conventional form--liver damage, acute and chronic pulmonary reactions, peripheral neuropathy, blood dyscrasias and allergic reactions--and does so just as rapidly and floridly; one such case is reported here.","label":1,"label_text":"Related"}
+{"text":"We cared for a patient with progressive renal impairment who presented with blurred vision, QRS broadening and cardiac failure due to chronic cibenzoline intoxication.","label":1,"label_text":"Related"}
+{"text":"We have recently encountered a patient with acquired haemophilia who developed a thrombotic left middle cerebral artery distribution stroke while being treated with pFVIII.","label":1,"label_text":"Related"}
+{"text":"Amphotericin B (AmB) is effective, but its use is limited by toxicity: renal impairment, anaemia, fever, malaise, and hypokalaemia are common.","label":1,"label_text":"Related"}
+{"text":"He had been receiving L-thyroxine therapy following mitral valve surgery.","label":0,"label_text":"Not-Related"}
+{"text":"Oral corticosteroids are the main therapeutic choice for systemic lupus erythematosus (SLE).","label":0,"label_text":"Not-Related"}
+{"text":"Emphasis is given to the differentiation of diphenylhydantoin induced gingival hyperplasia from the angiomatous enlargement of the gingiva before any treatment is planned.","label":1,"label_text":"Related"}
+{"text":"Osteonecrosis in patients with testicular tumours treated with chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"One woman received ifosfamide 1000 mg\/m2 (1 h infusion on days 1-5); confusion, lethargy, and speech deterioration developed on day 3.","label":0,"label_text":"Not-Related"}
+{"text":"Transplant recipients are at highest risk during the first 3 months posttransplant.","label":0,"label_text":"Not-Related"}
+{"text":"Initially, antipsychotics and especially pimozide were considered to be the pharmacological approach of choice but, subsequently, tryciclic anti-depressants and selective serotonin re-uptake inhibitors (SSRIs) were also suggested to be effective, implicating the serotonergic system in the pathophysiology of the disorder.","label":0,"label_text":"Not-Related"}
+{"text":"Iatrogenic central retinal vein occlusion and hyperviscosity associated with high-dose intravenous immunoglobulin administration.","label":0,"label_text":"Not-Related"}
+{"text":"We describe the case of a 36 year old patient who was admitted to the intensive care unit (ICU) for an acute asthma attack that failed to respond to conventional treatment and required mechanical ventilation.","label":0,"label_text":"Not-Related"}
+{"text":"In this study, we present a 75-year-old woman who had five children.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients developed diabetic coma when taking a combination of a thiazide diuretic and propranolol.","label":1,"label_text":"Related"}
+{"text":"Henna is a traditional cosmetic agent and is used worldwide.","label":0,"label_text":"Not-Related"}
+{"text":"Two cases are reported of patients who developed a hematologic malignancy several years after intravesical chemotherapy of superficial bladder cancer with etoglucid, doxorubicin, and mitomycin C.","label":1,"label_text":"Related"}
+{"text":"This cause of bleeding could not be brought under control endoscopically.","label":0,"label_text":"Not-Related"}
+{"text":"On January 29, the patient began having myoclonic muscle spasms.","label":0,"label_text":"Not-Related"}
+{"text":"She had multiple orthopedic interventions for kidney-related osteoarticular problems probably favored by the kidney graft and the immunosuppressive treatment.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of severe anemia, which responded well to steroid therapy, in a patient receiving IL-2 plus IFN-alpha for metastatic renal cell carcinoma.","label":1,"label_text":"Related"}
+{"text":"On patch testing, budesonide was strongly positive at day 2 and 3 in a concentration ranging from 1% to 10 p.p.m. (in petrolatum).","label":0,"label_text":"Not-Related"}
+{"text":"Recent trends in the diagnosis and management of typhilitis or neutropenic enterocolitis have been reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"HIT is an immune-mediated adverse drug reaction that may be associated with limb or life-threatening thrombosis.","label":0,"label_text":"Not-Related"}
+{"text":"Fortunately, however, the hepatotoxicity appears to resolve after discontinuation of the TMP-SMX therapy in most reported cases.","label":0,"label_text":"Not-Related"}
+{"text":"Venlafaxine, a structurally novel antidepressant, belongs to a new generation of antidepressants--the serotonin\/noradrenaline reuptake inhibitors.","label":0,"label_text":"Not-Related"}
+{"text":"Report of a fatal case.","label":0,"label_text":"Not-Related"}
+{"text":"Imidazoline intoxication in children.","label":1,"label_text":"Related"}
+{"text":"An extensive workup for other causes of eosinophilic pleural effusion was unrevealing.","label":0,"label_text":"Not-Related"}
+{"text":"The patient's score on the Naranjo adverse drug reaction probability scale indicated that the relationship between this adverse reaction and heparin was probable.","label":0,"label_text":"Not-Related"}
+{"text":"After development of the tics in 2, CBZ was continued at the same or higher dose, and the tics abated and then ceased spontaneously < or = 6 months.","label":0,"label_text":"Not-Related"}
+{"text":"A 64 year old man with recurrent metastatic squamous cell carcinoma of the head and neck developed severe skin rash and bone marrow aplasia 4 and 7 days, respectively, following a single dose of 40 mg\/m2 methotrexate (MTX).","label":1,"label_text":"Related"}
+{"text":"His extensive cytotoxic chemotherapy for AML is reviewed along with a discussion of its possible oncogenic effects.","label":0,"label_text":"Not-Related"}
+{"text":"Exacerbation of anthracycline-induced early chronic cardiomyopathy with ATRA: role of B-type natriuretic peptide as an indicator of cardiac dysfunction.","label":1,"label_text":"Related"}
+{"text":"Therefore, it is advisable to consider early glucocerebrosidase replacement therapy in GD patients receiving cytotoxic or targeted therapy for cancer.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was started on low molecular weight heparin, which resulted in resolution of her clinical condition.","label":0,"label_text":"Not-Related"}
+{"text":"An otolaryngology consultant performed fiberoptic laryngoscopy and paradoxical vocal cord movement was diagnosed.","label":0,"label_text":"Not-Related"}
+{"text":"Spontaneous recovery accompanied a reduction in steroid treatment to a low level.","label":0,"label_text":"Not-Related"}
+{"text":"We present three clinical cases of clostridial orthopedic infection and review the related medical literature.","label":0,"label_text":"Not-Related"}
+{"text":"The clinical picture was a severe alveolitis, with compromised gas exchange.","label":0,"label_text":"Not-Related"}
+{"text":"Hypersensitivity to carboplatin is a rare but real complication of therapy and should be considered in patients presenting with hyperacute changes on ECG whilst receiving carboplatin therapy.","label":1,"label_text":"Related"}
+{"text":"Intravenous valproate associated with significant hypotension in the treatment of status epilepticus.","label":1,"label_text":"Related"}
+{"text":"A clinical history was taken, and laboratory and imaging tests were performed.","label":0,"label_text":"Not-Related"}
+{"text":"A 72-year-old woman with a history of thyrotoxicosis presented with sore throat and fever two weeks after starting carbimazole.","label":1,"label_text":"Related"}
+{"text":"Abnormal air accumulation was noted in the bowel, peritoneum, mediastinum and retroperitoneum.","label":0,"label_text":"Not-Related"}
+{"text":"Its treatment consists of corticosteroids and\/or other immunosuppressive drug such as azathioprine, vincristine, cyclosporine, and mycophenolate mofetil.","label":0,"label_text":"Not-Related"}
+{"text":"Autoimmune thyroid disease is a common side-effect of interferon-alpha (IFN-alpha) treatment of viral hepatitis C.","label":1,"label_text":"Related"}
+{"text":"The patient underwent a successive surgical procedure without any adverse event.","label":0,"label_text":"Not-Related"}
+{"text":"We observed transient panhypogammaglobulinaemia in a patient with neuropsychiatric SLE after treatment with prednisolone and cyclophosphamide.","label":1,"label_text":"Related"}
+{"text":"Nephrotic syndrome related to systemic lupus erythematosus after griseofulvin therapy.","label":1,"label_text":"Related"}
+{"text":"INTRODUCTION: Although gefitinib used for the treatment of non-small-cell lung cancer is a well-known cause of interstitial lung disease (ILD), few case reports on erlotinib-induced ILD have been issued.","label":1,"label_text":"Related"}
+{"text":"This appearance should be considered as a possible false positive in patients undergoing such treatment who are being investigated with PET scans.","label":0,"label_text":"Not-Related"}
+{"text":"The profile of catecholamine metabolites changed: on day 150 of therapy, noradrenaline, adrenaline, and dopamine levels were increased, whereas HVA and VMA levels were decreased when compared to day 1 of therapy.","label":0,"label_text":"Not-Related"}
+{"text":"The bupivacaine concentration was reduced in a stepwise fashion from 0.5% to 0.25% and was changed to levobupivacaine after 3 days.","label":0,"label_text":"Not-Related"}
+{"text":"The administration of \"sweet spirits of nitre\" (4% ethyl nitrite CH3CH2ONO in 70% ethyl alcohol) was followed by acute methemoglobinemia and severe anoxic metabolic acidosis in infant twins, Methylene blue administration reversed methemoglobinemia in both, but one twin died from the consequences of hypoxemia.","label":1,"label_text":"Related"}
+{"text":"The first reported case, in an adult, of cholestyramine induced hyperchloremic metabolic acidosis is a 70 year old female with a two year history of primary biliary cirrhosis confirmed by histologic and immunologic criteria.","label":1,"label_text":"Related"}
+{"text":"The preliminary results (after 2 to 9 months of therapy) show 5 patients (24 per cent) did not benefit from the drug and 7 patients (33 per cent) are stable.","label":0,"label_text":"Not-Related"}
+{"text":"However, there can be a delay in diagnosing porphyria and a difficulty in selecting safe medicine for it even today.","label":0,"label_text":"Not-Related"}
+{"text":"However, 35% of the case reports involve patients with other illnesses, including 12 patients who did not have neoplasms.","label":0,"label_text":"Not-Related"}
+{"text":"The administration of \"sweet spirits of nitre\" (4% ethyl nitrite CH3CH2ONO in 70% ethyl alcohol) was followed by acute methemoglobinemia and severe anoxic metabolic acidosis in infant twins, Methylene blue administration reversed methemoglobinemia in both, but one twin died from the consequences of hypoxemia.","label":1,"label_text":"Related"}
+{"text":"Nonexcisional approaches include topical imiquimod, and curette and cryotherapy (C&C).","label":0,"label_text":"Not-Related"}
+{"text":"None of these patients had cystic or other significant macular changes.","label":0,"label_text":"Not-Related"}
+{"text":"Pure red cell aplasia after ABO-incompatible allogeneic stem cell transplantation in severe aplastic anemia with response to steroids: a case report and literature review.","label":0,"label_text":"Not-Related"}
+{"text":"The patient recovered with intensive supportive management including broad-spectrum antibiotics, bowel rest with gastric intubation and intravenous gamma-globulin.","label":0,"label_text":"Not-Related"}
+{"text":"This article reports the orthodontic treatment of 2 patients who were taking bisphosphonates.","label":0,"label_text":"Not-Related"}
+{"text":"A typical regimen is cytarabine 3 g\/m2 iv over one to three hours q 12h for a total of 8 to 12 doses.","label":0,"label_text":"Not-Related"}
+{"text":"Astute nursing care is essential to prevent complications associated with this procedure.","label":0,"label_text":"Not-Related"}
+{"text":"Vacuolar myelinopathy of the brain and lamellar ichthyosis.","label":0,"label_text":"Not-Related"}
+{"text":"The next morning the woman was improved and informed clinicians of her desmopressin use.","label":0,"label_text":"Not-Related"}
+{"text":"Extrapyramidal syndrome presenting as dysphagia: a case report.","label":0,"label_text":"Not-Related"}
+{"text":"The diffuse gastritis was aggressively treated with proton pump inhibitors.","label":0,"label_text":"Not-Related"}
+{"text":"Initial single rinsing with phosphate does not produce corneal calcification (P=0.134).","label":0,"label_text":"Not-Related"}
+{"text":"Three girls, two aged 12 years and one aged 17 years with refractory localization-related epilepsy were treated on an add-on basis with tiagabine.","label":0,"label_text":"Not-Related"}
+{"text":"We describe the development of cutaneous scleroderma in 3 patients coincident with the use of bleomycin in low cumulative doses of less than 100 U.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: Given the fulminant course of amphotericin B deoxycholate overdosage and lack of effective therapy, stringent safeguards against its improper administration should be in place.","label":0,"label_text":"Not-Related"}
+{"text":"A child with respiratory distress was found to have been given an antibiotic which was reconstituted with methadone.","label":0,"label_text":"Not-Related"}
+{"text":"Patients with HIV disease have a significantly higher prevalence of QTc prolongation than a general hospital-based population, may have an unrecognized acquired form of the long QT syndrome, and are at risk for torsades de pointes.","label":0,"label_text":"Not-Related"}
+{"text":"Aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension in a patient treated with trimethoprim-sulfamethoxazole.","label":1,"label_text":"Related"}
+{"text":"Rebound hyperglycemia was observed with both intermediate (neutral protamine hagedorn) and long-acting (protamine zinc iletin) insulins, and the range of insulin doses at which the disorder developed overlapped previously determined therapeutic doses for these insulins in the cat.","label":1,"label_text":"Related"}
+{"text":"A complication of short-term systemic corticosteroid use.","label":0,"label_text":"Not-Related"}
+{"text":"Depression is an extremely common illness in the elderly, and is, at times, refractory to the usual therapies.","label":0,"label_text":"Not-Related"}
+{"text":"Anticoagulant therapy was initiated with subcutaneous enoxaparin and oral warfarin.","label":0,"label_text":"Not-Related"}
+{"text":"In one instance a systemic hypoglycemic reaction resulting in head trauma and confusion ended in an emegency hospital admission following the substitution of acetohexamide for acetazolamide.","label":1,"label_text":"Related"}
+{"text":"The response of the occlusion of nearly all liver venules underlines the value of anti-inflammatory treatment combined with new thrombolytic medication such as defibrotide for the treatment of severe VOD.","label":0,"label_text":"Not-Related"}
+{"text":"The adrenaline concentration in the left femoral vein was twice as high compared to the right femoral vein.","label":0,"label_text":"Not-Related"}
+{"text":"The literature search found 12 cases of radiation recall caused by gemcitabine.","label":1,"label_text":"Related"}
+{"text":"CONTEXT: Previous investigators have reported discrepancies between hematologic, marrow morphologic, and cytogenetic responses to imatinib mesylate among patients with chronic myeloid leukemia (CML).","label":1,"label_text":"Related"}
+{"text":"After these 5 weeks of dosage increases, the INR became supratherapeutic for 3 weeks, resulting in a subsequent dosage decrease.","label":0,"label_text":"Not-Related"}
+{"text":"The cyclophosphamide (1 g\/m(2) per day) and thiotepa (80 mg\/m(2) per day) doses were based on body surface area (BSA) calculated using total body weight (TBW).","label":0,"label_text":"Not-Related"}
+{"text":"Long-term posaconazole treatment and follow-up of rhino-orbital-cerebral mucormycosis in a diabetic girl.","label":0,"label_text":"Not-Related"}
+{"text":"Cardiomyopathy after widely separated courses of adriamycin exacerbated by actinomycin-D and mithramycin.","label":1,"label_text":"Related"}
+{"text":"He presented with arthralgias, uveitis and respiratory insufficiency and developed hyperuricemic renal failure upon institution of treatment.","label":0,"label_text":"Not-Related"}
+{"text":"It is known to cause coagulation abnormalities, thrombosis and hemorrhage in the central nervous system in addition to vasculitis and hypersensitivity reactions.","label":0,"label_text":"Not-Related"}
+{"text":"Drug-induced hypersensitivity syndrome (DIHS)\/drug rash with eosinophilia and systemic symptoms (DRESS) is a severe multiorgan reaction with reactivation of herpesviruses.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Topiramate may be associated with ciliochoroidal effusion with forward displacement of the lens-iris diaphragm and anterior chamber shallowing, resulting in acute myopia and angle-closure glaucoma.","label":1,"label_text":"Related"}
+{"text":"Two prior episodes of visual loss had occurred during oral contraceptive treatment, an association not heretofore reported.","label":0,"label_text":"Not-Related"}
+{"text":"Clinically, the patient appeared cushingoid with a buffalo hump, thin skin, bruises, and purple striae, and his blood pressure was 130\/90 mm Hg.","label":0,"label_text":"Not-Related"}
+{"text":"Surprisingly, we found that three patients appeared to develop tardive OGC while taking clozapine.","label":1,"label_text":"Related"}
+{"text":"PVT during chemotherapy in children is a rare event and appears to be closely related to intensive chemotherapy containing busulfan and to be associated with HVOD.","label":1,"label_text":"Related"}
+{"text":"Naltrexone: report of lack of hepatotoxicity in acute viral hepatitis, with a review of the literature.","label":0,"label_text":"Not-Related"}
+{"text":"She received 600 mEq of sodium bicarbonate intravenously over 36 hours by which time her mentation, electrolytes and pH were normal.","label":0,"label_text":"Not-Related"}
+{"text":"However, graft function could not be restored.","label":0,"label_text":"Not-Related"}
+{"text":"Human chorionic gonadotrophin, administered exogenously as well as produced endogenously during pregnancy, is responsible for the onset of OHSS, and high levels of estradiol appear to worsen the condition.","label":0,"label_text":"Not-Related"}
+{"text":"Avascular necrosis of the femoral head in patients with prostate cancer treated with cyproterone acetate and radiotherapy.","label":1,"label_text":"Related"}
+{"text":"Antivenin reactions developed in three.","label":0,"label_text":"Not-Related"}
+{"text":"This case report describes a patient who developed a seizure with single-pulse transcranial magnetic stimulation during motor threshold estimation.","label":0,"label_text":"Not-Related"}
+{"text":"Microbiologic evaluation is essential for accurate early diagnosis and treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Serious infection during neutropenia was the most common complication.","label":0,"label_text":"Not-Related"}
+{"text":"During this period, urine losses of monovalent cation were only 55 mEq and body weight was constant at 48.2 kg.","label":0,"label_text":"Not-Related"}
+{"text":"Sunitinib is an orally administered multitargeted tyrosine kinase inhibitor that has demonstrated substantial antitumour activity in patients with metastatic renal cell carcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"This regime was well tolerated and we report dramatic resolution of the lesions with persistent clearance 6 months after completion of the fifth infusion.","label":0,"label_text":"Not-Related"}
+{"text":"Such a case induced by hypothyroidism complicating long-term therapy with amiodarone in a 45 year old woman with pre-excitation is presented.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: A subgroup of patients with idiopathic sensorineural hearing loss (SNHL) will have steroid-dependent symptoms which can be confirmed using pure-tone audiometry.","label":0,"label_text":"Not-Related"}
+{"text":"All three patients had to have treatment discontinued because of side effects, in part contributed to by preexisting medical problems, appeared.","label":0,"label_text":"Not-Related"}
+{"text":"Gaucher's disease (GD) is an autosomal recessive lysosomal storage disease resulting in an abnormal accumulation of glucocerebrosides in macrophages.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of mycosis fungoides with topical nitrosourea compounds: Further studies.","label":0,"label_text":"Not-Related"}
+{"text":"Dramatic clinical improvement occurred in 2 patients treated with high dose steroids.","label":0,"label_text":"Not-Related"}
+{"text":"Disseminated cellulitic cryptococcosis in the setting of prednisone monotherapy for pemphigus vulgaris.","label":1,"label_text":"Related"}
+{"text":"The most common presenting symptoms and signs were confusion, agitation, diaphoresis, tachycardia, myoclonus, and hyperreflexia.","label":0,"label_text":"Not-Related"}
+{"text":"Case 1, a 62-year-old woman, developed bilateral optic neuritis with decreased sensation of vibration and increased deep tendon reflex in the lower extremities after a seven-month use of recombinant interferon alpha-2a for chronic active hepatitis C.","label":1,"label_text":"Related"}
+{"text":"DATA SYNTHESIS: The first case describes a 15-year-old boy who received valproic acid and carbamazepine for partial seizures.","label":0,"label_text":"Not-Related"}
+{"text":"Pantavalent antimony can cause a wide range of adverse effects, the most serious of which are cardiotoxicity and hepatotoxicity.","label":0,"label_text":"Not-Related"}
+{"text":"Piritrexim-induced pulmonary toxicity.","label":1,"label_text":"Related"}
+{"text":"No cerebral lesion was detected.","label":0,"label_text":"Not-Related"}
+{"text":"We report a 14-year-old boy with high risk medulloblastoma treated with craniospinal radiation followed by chemotherapy, who experienced severe HSOS after only one course of chemotherapy including carboplatin, vincristine, and cyclophosphamide.","label":0,"label_text":"Not-Related"}
+{"text":"Hepato-biliary abnormalities secondary to ceftriaxone use: a case report.","label":1,"label_text":"Related"}
+{"text":"Interstitial pneumonitis and alveolar hemorrhage complicating use of rituximab: case report and review of the literature.","label":1,"label_text":"Related"}
+{"text":"Common adverse events (frequency 10%) of lacosamide doses up to 600 mg\/day include nonspecific central nervous system effects (e.g., dizziness, ataxia, diplopia, and somnolence).","label":1,"label_text":"Related"}
+{"text":"Medulloblastoma in a patient successfully treated for immature teratoma of the ovary.","label":0,"label_text":"Not-Related"}
+{"text":"The authors describe 4 cases of patients with bifurcation lesions involving the left anterior descending coronary artery, who developed periprocedural thrombosis with acute transmural ischemia.","label":0,"label_text":"Not-Related"}
+{"text":"A unique case of a transient, nonpigmenting fixed drug eruption caused by the radiopaque contrast medium iothalamate is reported.","label":1,"label_text":"Related"}
+{"text":"We describe the case of a girl with APECED, who presented with four endocrine (hypoparathyroidism, Addison's disease, hypothyroidism, gonadal failure) and three non-endocrine components (candidiasis, ectodermal dystrophy and lichen ruber planus).","label":0,"label_text":"Not-Related"}
+{"text":"In three of the patients drug kinetic investigations were performed and revealed a slow metabolizer status.","label":0,"label_text":"Not-Related"}
+{"text":"Rejection of blood transfusions by individuals of this faith is usually blamed to justify this attitude, thus leading to severe personal, medical and psychological distress related to the lack of care.","label":0,"label_text":"Not-Related"}
+{"text":"Acute non-lymphocytic leukemia occurred in eight women following long-term treatment with Treosulfan (= dihydroxybusulfan) for ovarian carcinoma.","label":1,"label_text":"Related"}
+{"text":"Donepezil therapy was discontinued prematurely in three of the cases due to insufficient response and\/or adverse events.","label":0,"label_text":"Not-Related"}
+{"text":"Ventricular systolic function recovered completely by the fourth hospital day.","label":0,"label_text":"Not-Related"}
+{"text":"Quinapril is an angiotensin-converting enzyme inhibitor (ACE-inhibitor) and overdose can lead to prolonged hypotension and, less frequently, transient renal impairment.","label":1,"label_text":"Related"}
+{"text":"The other two patients developed immune-related adverse events (irAEs) including rash (one case; grade 2) and diarrhoea (both cases; grades 1 and 2, respectively); the histopathology of colon biopsy samples from both was suggestive of colitis, with an abundant CD8+ T-cell infiltrate.","label":0,"label_text":"Not-Related"}
+{"text":"DISCUSSION: After exclusion of other causes, the onset of thrombocytopenia after administration of lansoprazole, the resolution of the adverse reaction after discontinuation of the drug, and the fact that no other medicines were introduced during this time frame lead us to believe that this was most likely an idiosyncratic thrombocytopenic response to lansoprazole.","label":1,"label_text":"Related"}
+{"text":"Treatment with methoxsalen and UV-A radiation successfully cleared the photosensitive eruption in the patients.","label":0,"label_text":"Not-Related"}
+{"text":"Adriamycin-induced cardiomyopathy aggravated by cis-platinum nephrotoxicity requiring dialysis.","label":1,"label_text":"Related"}
+{"text":"Interferon-alpha affects the immune response in post-transplant lymphoproliferative disorder.","label":0,"label_text":"Not-Related"}
+{"text":"Transarterial membranotomy and repeated infusion of thrombolytic agents and anticoagulants directly in the thrombus brought about improvement of the circulation surrounding the liver and IVC, and recovery from hepatic failure.","label":0,"label_text":"Not-Related"}
+{"text":"The eruption in this case may have been an allergic reaction arising in a depressed immunity induced by chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Severe rash, including the Stevens-Johnson syndrome (SJS), is the major toxicity of nevirapine and is described in the package labeling with a prominent, boxed warning.","label":1,"label_text":"Related"}
+{"text":"Clinico-pathological correlations were made.","label":0,"label_text":"Not-Related"}
+{"text":"Only three cases have been described in the literature.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of a patient suspected of voluntary massive poisoning by ethylene glycol.","label":0,"label_text":"Not-Related"}
+{"text":"The pharmacology of the drug and therapeutic experiences in 6 cases are described.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: The aim of this paper is to describe a case of increased libido during fluvoxamine therapy.","label":1,"label_text":"Related"}
+{"text":"We report on a patient in whom a giant thrombus in the left atrium was detected by transthoracic echocardiography.","label":0,"label_text":"Not-Related"}
+{"text":"From these experiences panic anxiety seemed to be a withdrawal symptom, and involvement of the noradrenergic system in panic anxiety as well as serotonergic system was suggested.","label":0,"label_text":"Not-Related"}
+{"text":"The diagnosis was initially thought to be a recurrence of idiopathic thrombocytopenic purpura (ITP) that had initially occurred in 1992 and had required splenectomy.","label":0,"label_text":"Not-Related"}
+{"text":"A case of pseudotumor cerebri following glucocorticoid therapy in which warfarin prevented recurrence.","label":0,"label_text":"Not-Related"}
+{"text":"Bosentan and warfarin interaction.","label":0,"label_text":"Not-Related"}
+{"text":"The rarity of severe complications in this situation warrants presentation of the following unique association.","label":0,"label_text":"Not-Related"}
+{"text":"Its use is considered to be less harmful than the effect of active disease on the fetus.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of drug-induced Kaposi's sarcoma (KS) on the sole of the right foot in a 71-year-old man, treated for 6 months with corticosteroid therapy (prednisolone 25 mg\/day) for pericardial effusion.","label":1,"label_text":"Related"}
+{"text":"Using micro broth dilution technique the isolated strain was shown to be most susceptible to penicillin G, cephalothin, and ciprofloxacin, with minimal inhibitory concentrations of 0.00025, 0.004, and 0.002 mg\/l, respectively; and with minimal bactericidal concentrations (99.9% killing) of 0.25, 0.12, and 0.008 mg\/l, respectively.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND CONTEXT: Spontaneous spinal epidural hematoma (SSEH) is an infrequent spinal pathology.","label":0,"label_text":"Not-Related"}
+{"text":"The incidence of 5-fluorouracil (5-FU)-related cardiotoxicity seems to be dosage and schedule dependent.","label":1,"label_text":"Related"}
+{"text":"This patient's experience stresses the need to consider beta-blockers as a potentially reversible cause of memory impairment.","label":0,"label_text":"Not-Related"}
+{"text":"Subsequent in vivo\/vitro studies clearly demonstrated that the neurological effects were due to a synergistic action of desferrioxamine and prochlorperazine, probably resulting in exceptional fluxes of intra\/extra cellular iron\/copper disturbing noradrenergic and serotonergic systems.","label":1,"label_text":"Related"}
+{"text":"The purpose of this work is to report the case of oral chemical burns caused by topical self-medication for tooth pain relief, and also to discuss the clinical presentation and the treatment performed.","label":0,"label_text":"Not-Related"}
+{"text":"During four courses of chemotherapy for a disseminated testicular seminoma a 30-year-old man developed three arterial occlusive events and one silent myocardial infarction.","label":0,"label_text":"Not-Related"}
+{"text":"Most cases are due to Candida spp. while Aspergillus spp. and zygomycetes have only rarely been implicated.","label":0,"label_text":"Not-Related"}
+{"text":"Three cases of self-inflicted gingival injuries resulting from the improper use of the Keyes technique are presented.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of periocular capillary hemangioma with topical clobetasol propionate.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of a patient who developed polyserositis (pericardial effusion, pleural effusion, and pericarditis) after being started on clozapine, and whose symptoms remitted upon discontinuation of clozapine.","label":1,"label_text":"Related"}
+{"text":"Two adverse effects were reported: 1 case of reversible urinary retention and 1 case of deficiency of the dorsiflexor muscles of the foot.","label":0,"label_text":"Not-Related"}
+{"text":"G-CSF was successful in producing a rise in neutrophil count which coincided with a resolution of fever; there was no adverse effect on renal function.","label":0,"label_text":"Not-Related"}
+{"text":"The use of sulfonylurea medications in the treatment of type 2 diabetes mellitus is common.","label":0,"label_text":"Not-Related"}
+{"text":"He recovered successfully after treatment with very high doses of corticosteroids and azathioprine.","label":0,"label_text":"Not-Related"}
+{"text":"Latero-lateral anastomosis between the common bile duct and duodenum was performed during explorative laparotomy and ursodeoxycholic acid treatment was introduced.","label":0,"label_text":"Not-Related"}
+{"text":"A systematic investigation ruled out causes of physiological and reactive thrombocytoses.","label":0,"label_text":"Not-Related"}
+{"text":"DISCUSSION: The Naranjo probability scale indicated a probable relationship between sertraline treatment and the onset of rhabdomyolysis.","label":1,"label_text":"Related"}
+{"text":"We present a case of documented N. sicca peritonitis immediately following an episode of Staphylococcus aureus peritonitis in a pediatric chronic peritoneal dialysis (CPD) patient.","label":0,"label_text":"Not-Related"}
+{"text":"Thirty months after the start of chemotherapy, preleukemic changes were observed in peripheral blood and bone marrow, and acute nonlymphocytic leukaemia (M5 of the FAB classification) was diagnosed shortly afterwards.","label":0,"label_text":"Not-Related"}
+{"text":"Reversal of ergotamine-induced arteriospasm by mechanical intra-arterial dilatation.","label":1,"label_text":"Related"}
+{"text":"We suggest being aware of such reactions during omeprazole usage.","label":0,"label_text":"Not-Related"}
+{"text":"Both patients (27 wk, 5 d; and 26 wk, 6 d of gestation) underwent surgical arterial duct ligation and coarctation repair.","label":0,"label_text":"Not-Related"}
+{"text":"The final pathologic examination confirmed high-grade leiomyosarcoma.","label":0,"label_text":"Not-Related"}
+{"text":"Our patient presented at the emergency department with an increasing scalp swelling for 2 weeks, and culture of the evacuated fluid yielded Streptococcus pneumoniae.","label":0,"label_text":"Not-Related"}
+{"text":"The purpose of this paper is to illustrate a retrospective case report demonstrating drug extravasation caused by the development of fibrin sheath formation.","label":0,"label_text":"Not-Related"}
+{"text":"Caution is emphasized in the use of carbonic anhydrase inhibitors in patients with obstructive airway disease.","label":0,"label_text":"Not-Related"}
+{"text":"Possible linkage of amprenavir with intracranial bleeding in an HIV-infected hemophiliac.","label":1,"label_text":"Related"}
+{"text":"This regimen should decrease the risk of antibiotic induced nephrotoxicity, but it requires further study.","label":0,"label_text":"Not-Related"}
+{"text":"Medical management of the head and neck cancer patient (HNCP) most often will include radiation therapy to the head and neck region.","label":0,"label_text":"Not-Related"}
+{"text":"In case 1, a total daily dose of 25 mg sertraline, with nondetectable sertraline and desmethylsertraline blood levels, resulted in a doubling of the lamotrigine blood level with symptoms of toxicity.","label":1,"label_text":"Related"}
+{"text":"The drug was immediately withdrawn and the patient was given glibenclamide.","label":0,"label_text":"Not-Related"}
+{"text":"Blood pressures continued to increase, however, and late postpartum eclampsia developed.","label":0,"label_text":"Not-Related"}
+{"text":"Methotrexate is an effective but potentially toxic treatment for psoriasis.","label":1,"label_text":"Related"}
+{"text":"Erythromycin is a macrolide antibiotic that may increase the risk of lovastatin-induced rhabdomyolysis.","label":1,"label_text":"Related"}
+{"text":"We describe a case of interstitial hypoxaemiant pneumonitis probably related to flecainide in a patient with the LEOPARD syndrome, a rare congenital disorder.","label":1,"label_text":"Related"}
+{"text":"We recommend the cautious use of alum irrigation in patients with renal impairment and monitoring of serum aluminum levels to prevent excessive accumulation and toxicity.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: A 40-year-old patient developed painless corneal edema despite minimal epithelial injury after exposure to ushaar latex.","label":0,"label_text":"Not-Related"}
+{"text":"The most common chemotherapeutic agents implicated are anthracyclines and taxanes.","label":0,"label_text":"Not-Related"}
+{"text":"The patient described feeling cold with worsening headache and chills approximately one hour after infusion of the first dose of penicillin.","label":1,"label_text":"Related"}
+{"text":"Intranasal desmopressin-induced hyponatremia.","label":1,"label_text":"Related"}
+{"text":"When measured, the serum lithium level had increased 4-fold during acyclovir therapy.","label":1,"label_text":"Related"}
+{"text":"Steroids also contributed to the improvement of the nephrotic syndrome and proteinuria decreased from maximal ranges of 27 g\/l to 2.2 g\/l after six months of the follow-up.","label":0,"label_text":"Not-Related"}
+{"text":"The thyroid gland was not enlarged or tender.","label":0,"label_text":"Not-Related"}
+{"text":"Since July 1985, 23 patients have been entered into a phase I\/II clinical trial using intraarterial 5-bromodeoxyuridine (BUdR) (400-600 mg\/m2 daily for 8.5 weeks) and focal external beam radiotherapy (59.4 Gy at 1.8 Gy daily in 6.5 weeks) in the treatment of malignant gliomas (Kernohan grades 3 and 4).","label":0,"label_text":"Not-Related"}
+{"text":"Two cases of lepromatous leprosy with erythema nodosum leprosum who were on high doses of clofazimine, showed discoloration of nail plate, subungual hyperkeratosis and onycholysis.","label":1,"label_text":"Related"}
+{"text":"Following intravenous hydration and administration of bicarbonate, the patients' condition resolved without permanent' sequelae.","label":0,"label_text":"Not-Related"}
+{"text":"In the following case report, a patient developed acute interstitial nephritis with renal failure and exfoliative dermatitis following ampicillin therapy.","label":1,"label_text":"Related"}
+{"text":"Ptosis occurring 24 h after chloroquine therapy, with full recovery 48 h after cessation of chloroquine, has not been described previously.","label":1,"label_text":"Related"}
+{"text":"Before invasive procedures are performed, thought must be given to what changes in treatment may be made when results are known.","label":0,"label_text":"Not-Related"}
+{"text":"Generalised cutaneous rash associated with ganciclovir therapy has rarely been reported in literature.","label":1,"label_text":"Related"}
+{"text":"Acute renal failure caused by fungal bezoar: a late complication of Candida sepsis associated with central catheterization.","label":0,"label_text":"Not-Related"}
+{"text":"In this report, we describe a novel presentation of interface inflammation that resembles DLK in appearance but presents late in the postoperative period, is associated with increased intraocular pressure, and is exacerbated by steroid treatment.","label":0,"label_text":"Not-Related"}
+{"text":"We discuss the possible causes of stroke.","label":0,"label_text":"Not-Related"}
+{"text":"Carcinoma arising in the pleural cavity following pneumonectomy for hydatid disease.","label":0,"label_text":"Not-Related"}
+{"text":"Hemoglobin levels normalized after administration of enalapril was stopped.","label":0,"label_text":"Not-Related"}
+{"text":"Because of its selective action on B lymphocytes, it is considered a moderate immunosuppressant in terms of infection.","label":0,"label_text":"Not-Related"}
+{"text":"Right internal carotid artery occlusion during intravenous thrombolysis for left middle cerebral artery occlusion.","label":0,"label_text":"Not-Related"}
+{"text":"When SASP was changed to 5-aminosalicylic acid (5-ASA), his skin eruptions were resolved, however, he developed weakness and atrophy in his right arm as well as progressive worsening of the dysesthesia in his legs and gait disturbance.","label":1,"label_text":"Related"}
+{"text":"Four of the patients reported erectile dysfunction before beginning apomorphine and two of these report a significant improvement in their sexual function resulting from apomorphine use.","label":0,"label_text":"Not-Related"}
+{"text":"Shewanella spp. infection following treatment for upper gastrointestinal bleeding.","label":0,"label_text":"Not-Related"}
+{"text":"Our report points out differences between acute, postacute, and longterm rehabilitation, describes the mobilization of patients in acute rheumatology units, and defines specific problems encountered in acute hospital-based rehabilitation of rheumatological patients.","label":0,"label_text":"Not-Related"}
+{"text":"Attempts at anticoagulation with oral warfarin were unsuccessful while the patient was receiving 50-100 ml\/hr of Osmolite through an Entriflex feeding tube and intermittent oral Ensure Plus supplements.","label":0,"label_text":"Not-Related"}
+{"text":"While exclusion of any bacterial infection and screening for tuberculosis are mandatory before initiating a therapy with anti-TNF-alpha-antibodies, there are no guidelines whether to screen for or how to deal with chronic viral infections such as hepatitis B.","label":0,"label_text":"Not-Related"}
+{"text":"Systemic allergic reactions to aprotinin injection around the Achilles tendon.","label":0,"label_text":"Not-Related"}
+{"text":"Because of the difficulty of case collection, understanding of the association of MAHA and anal squamous cell carcinoma remains vague.","label":0,"label_text":"Not-Related"}
+{"text":"There was no correlation between onset of symptoms and CyA levels.","label":0,"label_text":"Not-Related"}
+{"text":"His thigh was indeed in close contact with his trousers pocket where he used to store a wiping rag drenched into white spirit and cellulosic thinner.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of ELP in children is generally supportive, with the symptoms and roentgenographic abnormalities resolving within months after stopping the use of mineral oil.","label":1,"label_text":"Related"}
+{"text":"I report a 35-year-old woman with occult coronary artery disease who experienced cardiac arrest within minutes after receiving a first-time dose of subcutaneous sumatriptan for migraine.","label":1,"label_text":"Related"}
+{"text":"Although tardive dyskinesia is a known adverse reaction of sustained treatment with traditional neuroleptic agents, it was only rarely reported in association with sulpiride, a selective D2-receptor antagonist.","label":1,"label_text":"Related"}
+{"text":"CASE SUMMARY: A 65-year-old patient chronically treated with the selective serotonin reuptake inhibitor (SSRI) citalopram developed confusion, agitation, tachycardia, tremors, myoclonic jerks and unsteady gait, consistent with serotonin syndrome, following initiation of fentanyl, and all symptoms and signs resolved following discontinuation of fentanyl.","label":1,"label_text":"Related"}
+{"text":"Four of these were derived from a study of 100 schizophrenic patients on maintenance neuroleptic medication, thereby giving a prevalence of 4% in such patients.","label":0,"label_text":"Not-Related"}
+{"text":"Lithium treatment was terminated in 1975 because of lithium intoxication with a diabetes insipidus-like syndrome.","label":1,"label_text":"Related"}
+{"text":"Digestive hemorrhage caused by a Meckel's diverticulum in a metformin-treated patient: is there any connection?","label":1,"label_text":"Related"}
+{"text":"Nucleotide sequence of the UL54 and UL97 of the clinical isolate showed 4 amino acid substitutions (V11L, Q578H, S655L, and G874R) in UL54 and 2 mutations (A140V and A594V) in UL97 compared with the Towne and AD169 strains.","label":0,"label_text":"Not-Related"}
+{"text":"One patient improved after withdrawal of dextroamphetamine; others had worsening of their symptoms on higher doses of medications.","label":0,"label_text":"Not-Related"}
+{"text":"The evidence from this series of cases and from six additional cases identified in the literature suggests that the risk of endometrial sarcomas may be increased by estrogen therapy or endogenous disorders that lead to unopposed estrogenic stimulation of the uterus.","label":0,"label_text":"Not-Related"}
+{"text":"Vancomycin is widely used against methicillin-resistant Staphylococcus aureus infections, but it is associated with many adverse effects such as nephrotoxicity, ototoxicity, gastrointestinal disturbances, blood disorders, and two types of hypersensitivity reactions - an anaphylactoid reaction known as \"red man syndrome\" and anaphylaxis.","label":1,"label_text":"Related"}
+{"text":"Indicators suggesting review by appropriate medical personnel for possible clonazepam behavioral side effects are provided.","label":0,"label_text":"Not-Related"}
+{"text":"It is tempting to speculate that interferon alpha may be involved in the pathogenesis of lichen nitidus.","label":1,"label_text":"Related"}
+{"text":"This article reports the impact of inadvertent acyclovir exposure on a woman during the first trimester of pregnancy and reviews the literature on acyclovir's pharmacology, safety profile, and potential uses during pregnancy.","label":0,"label_text":"Not-Related"}
+{"text":"This case illustrated the importance of early diagnosis of sympathetically mediated chest pain and role of Stellate ganglion block.","label":0,"label_text":"Not-Related"}
+{"text":"When SASP was changed to 5-aminosalicylic acid (5-ASA), his skin eruptions were resolved, however, he developed weakness and atrophy in his right arm as well as progressive worsening of the dysesthesia in his legs and gait disturbance.","label":1,"label_text":"Related"}
+{"text":"The \"pinch-off sign\" was noted on a routine chest X-ray but that was ignored.","label":0,"label_text":"Not-Related"}
+{"text":"Surgical resection, when possible, and prolonged treatment with amphotericin provide the most effective form of therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Interstitial pneumonitis associated with sirolimus: a dilemma for lung transplantation.","label":1,"label_text":"Related"}
+{"text":"Clinical examinations and slit-lamp photographs, over an average of 21.3 +\/- 7.2 months (range, 11 to 31 months), documented the effects of different treatment modalities.","label":0,"label_text":"Not-Related"}
+{"text":"The discolouration resolved when the creams were ceased.","label":0,"label_text":"Not-Related"}
+{"text":"Subsequent progression of cataract required cataract extraction, which resulted in a very rapid progression of the exudative macular degeneration and loss of vision.","label":0,"label_text":"Not-Related"}
+{"text":"The effect of pergolide on nocturia was independent of improvement of parkinsonian symptoms, suggesting a distinct mechanism from that of anti-parkinsonian effects.","label":0,"label_text":"Not-Related"}
+{"text":"We describe the clinical course of 2 patients with Crohn's disease (CD) in whom lymphoma was diagnosed after treatment with infliximab.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: A 26-year-old man with bipolar disorder developed hyperammonemia three weeks after initiating carbamazepine therapy.","label":1,"label_text":"Related"}
+{"text":"These observations suggest that depressed thyroid function may be protective against arrhythmias but a patient with preexisting conduction system disease may develop AV block.","label":0,"label_text":"Not-Related"}
+{"text":"While reactivation Histoplasmosis has been reported in the setting of immunosuppression, it remains unclear whether remote primary latent infection represents risk of endogenous reactivation after anti-tumor necrosis factor (TNF)-alpha therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Examination revealed confusion, jaundice, signs of chronic liver disease, portal hypertension and hepatic encephalopathy.","label":0,"label_text":"Not-Related"}
+{"text":"PPI-delayed diagnosis of gastrinoma: oncologic victim of pharmacologic success.","label":0,"label_text":"Not-Related"}
+{"text":"PURPOSE: To report the safety and efficacy of intravitreal triamcinolone in the treatment of inflammatory cystoid macular oedema (CMO) in six patients who were resistant to other forms of therapy.","label":0,"label_text":"Not-Related"}
+{"text":"A patient receiving vancomycin for a serious staphylococcal infection had a lupus-like syndrome characterized by a malar rash, pain and erythema of the cartilage of both ears, and tender erythematous and hemorrhagic lesions of the finger tips.","label":1,"label_text":"Related"}
+{"text":"She did not use contact lenses postoperatively.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a heroin abuser in whom clinical and laboratory manifestations of acute hepatitis B and C appeared a few days after the insertion of a subcutaneous naltrexone implant.","label":1,"label_text":"Related"}
+{"text":"Selective estrogen receptor modulator raloxifene-associated aggravation of nonalcoholic steatohepatitis.","label":1,"label_text":"Related"}
+{"text":"Two patients with COMT inhibitor-induced hepatic dysfunction and UGT1A9 genetic polymorphism.","label":0,"label_text":"Not-Related"}
+{"text":"A 25-year-old factory worker sustained inhalation injury and 2 per cent deep burns while fighting a fire in his factory (LSI factory) which was made of new synthetic building materials.","label":0,"label_text":"Not-Related"}
+{"text":"Ciprofloxacin-induced hemorrhagic vasculitis is a rare side effect.","label":1,"label_text":"Related"}
+{"text":"A retrospective analysis using a bone marrow sample showed the presence of chimerism already at a time when the characteristic full clinical picture of graft versus host disease had not yet developed, opening the way for the early diagnosis and treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Sedative effects may, in fact, be mediated through the benzodiazepine receptor.","label":0,"label_text":"Not-Related"}
+{"text":"It may be concluded that rhEPO is possibly effective in a subgroup of MDS patients where the disease is less advanced.","label":0,"label_text":"Not-Related"}
+{"text":"SUMMARY OF BACKGROUND DATA: CPS has a risk of vertebral artery (VA) injury.","label":0,"label_text":"Not-Related"}
+{"text":"The authors present a woman with profound lower extremity weakness and sensory abnormality after falling asleep in the head-to-knees yoga position (also called \"Paschimottanasana\").","label":0,"label_text":"Not-Related"}
+{"text":"Phenylpropanolamine (PPA) is a sympathomimetic drug contained in numerous over-the-counter and prescription decongestants and appetite suppressants.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: Infliximab can be used successfully for the treatment of pediatric patients with Crohn's disease and IPAA who are refractory to conventional therapies.","label":0,"label_text":"Not-Related"}
+{"text":"The visual loss in this patient seems to result from phenol neurotoxicity rather than mechanical compression of the intraorbital optic nerve.","label":1,"label_text":"Related"}
+{"text":"Granulocyte colony stimulating factor (GCSF) was administered to one patient and in another a bone marrow biopsy was performed due to persistent anemia, leukopenia, and thrombocytopenia.","label":0,"label_text":"Not-Related"}
+{"text":"Surgeons should consider stopping carbamazepine before operations with cardiopulmonary bypass.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Five patients were identified.","label":0,"label_text":"Not-Related"}
+{"text":"Second-line chemotherapy with pemetrexed 500 mg\/m2 intravenously every 3 weeks was commenced.","label":0,"label_text":"Not-Related"}
+{"text":"Confirmation of the suspected drugs that cause hypersensitivity reaction is sometimes difficult.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of anticholinergic-induced ileus with neostigmine.","label":0,"label_text":"Not-Related"}
+{"text":"MAHA developed 2 months later, and tumor recurrence with rapid deterioration appeared 5 months later.","label":0,"label_text":"Not-Related"}
+{"text":"A 66-year-old mand suffering from severe coronary heart disease took digoxin with suicidal intent an was treated for the ensuing complete atrioventricular block with digoxin-specific antibody fragments.","label":1,"label_text":"Related"}
+{"text":"OBJECTIVE: To report a case of possible foscarnet-induced severe hypomagnesemia and other electrolyte disorders.","label":1,"label_text":"Related"}
+{"text":"Inadvertent globe perforation resulted in subsequent rhegmatogenous retinal detachment.","label":0,"label_text":"Not-Related"}
+{"text":"We present the first case of WES in an infant born to a mother taking haloperidol during her pregnancy.","label":1,"label_text":"Related"}
+{"text":"This is a report of a 9-year-old epileptic boy, who was studied over a period of 7 years.","label":0,"label_text":"Not-Related"}
+{"text":"A case of phenytoin-induced hepatitis with mononucleosis is reported, and syndromes associated with phenytoin hypersensitivity reactions are discussed.","label":1,"label_text":"Related"}
+{"text":"Gemcitabine is a known risk factor for hemolytic uremic syndrome (HUS), which can often have a rapidly fatal clinical course despite intervention with steroids, plasmapheresis and hemodialysis.","label":1,"label_text":"Related"}
+{"text":"A longitudinal case report shows a sudden remission of the severe course of a seasonal bipolar disorder after 10 years of psychopharmacological treatments.","label":0,"label_text":"Not-Related"}
+{"text":"Red blood cell anemia in a patient with pemphigus vulgaris induced by the use of mycophenolate mofetil and prednisone.","label":1,"label_text":"Related"}
+{"text":"Aggressive management of doxorubicin-induced cardiomyopathy associated with 'low' doses of doxorubicin.","label":1,"label_text":"Related"}
+{"text":"Ultrastructural, fluorescent, and energy-dispersive x-ray microanalysis study.","label":0,"label_text":"Not-Related"}
+{"text":"A pituitary adenoma was removed, vision recovered, and the pregnancy completed successfully.","label":0,"label_text":"Not-Related"}
+{"text":"We describe the exceptional development of AML and lung cancer in a patient with previously diagnosed CLL in minimal residual disease status after fludarabine treatment followed by autologous peripheral blood stem-cell transplantation.","label":1,"label_text":"Related"}
+{"text":"METHODS: Eight patients with cutaneous ulcerations from cryofibrinogenemia were treated with stanozolol.","label":0,"label_text":"Not-Related"}
+{"text":"Subsequently, in 1998, the observation of a significant 49% reduction in invasive breast cancer relative to placebo in a cohort of women at increased risk for the disease resulted in the early stopping of the National Surgical Adjuvant Breast and Bowel Project's (NSABP) P-1: Breast Cancer Prevention Trial (BCPT).","label":0,"label_text":"Not-Related"}
+{"text":"The pharmacologic agent bisphosphonate has recently received much attention in the dental literature.","label":0,"label_text":"Not-Related"}
+{"text":"The authors reported two cases of vasculonecrotic phenomena in lepromatous leprosy sharing clinical and histopathological characteristics of both reaction subtypes.","label":0,"label_text":"Not-Related"}
+{"text":"Investigation revealed advanced metastatic disease with a probable primary in the right lung.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: Two patients with long-term hydroxychloroquine use, subtle perifoveal ophthalmoscopic pigmentary changes, and bilateral perifoveal defects on automated Humphrey visual field (HVF) 10-2 perimetry were imaged using SD-OCT and AO.","label":0,"label_text":"Not-Related"}
+{"text":"The international literature regarding opportunistic infections after immunosuppressive therapy with alemtuzumab with particular attention on fungal infections has also been reviewed.","label":1,"label_text":"Related"}
+{"text":"The pathophysiology and management of myoclonus are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"We report a patient with pulmonary adenocarcinoma complicated by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) following systemic chemotherapy with cisplatin (CDDP) and vindesine (VDS).","label":1,"label_text":"Related"}
+{"text":"We describe a case of recurrent impetigo herpetiformis in an 18-year-old pregnant woman who had normal serum calcium levels and responded well to prednisolone therapy.","label":0,"label_text":"Not-Related"}
+{"text":"In all patients, the IOP increase was sustained across several visits, requiring control with topical glaucoma therapy, and in two cases the addition of a systemic carbonic anhydrase inhibitor.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: Acetic acid is corrosive and may cause vagina bleeding.","label":1,"label_text":"Related"}
+{"text":"The patient had none of the risk factors known to influence the response to the coumarinic derivative except that she carried the rare *3 allelic variant of the cytochrome P450 CYP2C9 in a homozygous status.","label":0,"label_text":"Not-Related"}
+{"text":"It remains to be seen whether the hepatotoxicity associated with troglitazone is a drug-class effect or specific to troglitazone.","label":1,"label_text":"Related"}
+{"text":"Mycosis fungoides progression and chronic solvent exposure.","label":0,"label_text":"Not-Related"}
+{"text":"The clinical course suggested that recombinant alpha-2b peginterferon plus ribavirin provoked type 1 diabetes mellitus, therefore, in patients who are candidates for interferon therapy the presence of pancreatic autoantibodies and the fasting plasma glucose level should be investigated before and during treatment.","label":1,"label_text":"Related"}
+{"text":"Sprague Dawley and Brown Norway rats were ovariectomized and randomly assigned to treatment groups (subcutaneous implantation of either a capsule containing 20 mg 17beta-estradiol or an empty capsule, as a control).","label":0,"label_text":"Not-Related"}
+{"text":"We report a patient with supralethal magnesemia of 38.7 mg\/dL who survived.","label":0,"label_text":"Not-Related"}
+{"text":"The patient demonstrated radiographic signs of pulmonary aspergillosis and biochemical signs of hepatic involvement that were resistant to a 23 day course of conventional AMB (Fungizone) therapy.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Infants can be exposed to clinically relevant doses of lamotrigine through breast-feeding.","label":0,"label_text":"Not-Related"}
+{"text":"Combination cytotoxic chemotherapy was used to treat a case of acute myeloid leukaemia presenting in the 25th week of pregnancy with a sustained complete remission of the leukaemia and the successful delivery of a normal infant.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of Paecilomyces infections may require multiple courses of antifungal therapy, often with surgical debridement.","label":0,"label_text":"Not-Related"}
+{"text":"Two ajmaline tests were both negative and ruled out the diagnosis of BS.","label":0,"label_text":"Not-Related"}
+{"text":"A drug-induced psoriasiform eruption due to these drugs seems to be more common than previously reported.","label":0,"label_text":"Not-Related"}
+{"text":"TEN is often a drug-induced reaction and virtually any drug class appears capable of provoking it.","label":0,"label_text":"Not-Related"}
+{"text":"The report emphasizes a thorough and detailed assessment of deaths which occur during treatment with neuroleptic drugs.","label":0,"label_text":"Not-Related"}
+{"text":"Development of an organic affective syndrome during a hyperbaric diving experiment.","label":0,"label_text":"Not-Related"}
+{"text":"A case of actinic prurigo and solar urticaria.","label":0,"label_text":"Not-Related"}
+{"text":"Dapsone is increasingly used in the treatment of rheumatic diseases.","label":0,"label_text":"Not-Related"}
+{"text":"After ciprofloxacin treatment, the ulcer healed and visual acuity recovered to 20\/20 with spectacle correction.","label":0,"label_text":"Not-Related"}
+{"text":"The patient's blurred vision gradually improved, but visual field defect remained.","label":0,"label_text":"Not-Related"}
+{"text":"This was felt to be primarily induced by doxorubicin.","label":0,"label_text":"Not-Related"}
+{"text":"Enuresis is a common paediatric problem which is sometimes treated with anticholinergic drugs.","label":0,"label_text":"Not-Related"}
+{"text":"The authors present an elderly patient with mixed dementia who developed TD at multiple sites, (including respiratory dyskinesia [RD], limb dyskinesia, and orofacial dyskinesia) following abrupt withdrawal of risperidone therapy.","label":1,"label_text":"Related"}
+{"text":"A case report.","label":0,"label_text":"Not-Related"}
+{"text":"CASE REPORTS: Case 1.","label":0,"label_text":"Not-Related"}
+{"text":"Furthermore, this analysis does not provide evidence for a heightened risk of AML\/MDS in CLL patients, despite treatment with known leukemogenic agents.","label":0,"label_text":"Not-Related"}
+{"text":"The other patient had dienestrol, 2.5 mg daily, and later estradiol, 40 mg every 6 weeks.","label":0,"label_text":"Not-Related"}
+{"text":"Objective antitumor responses and significant palliation of symptoms have been demonstrated.","label":0,"label_text":"Not-Related"}
+{"text":"Pancytopenia associated with 5-aminosalicylic acid use in a patient with Crohn's disease.","label":1,"label_text":"Related"}
+{"text":"Intensive high-flux hemodiafiltration is often used in the management of vancomycin toxicity.","label":1,"label_text":"Related"}
+{"text":"Treatment by nitrogen-oxygen saturation at a pressure equivalent of 30 m (100 ft) sea water is proposed.","label":0,"label_text":"Not-Related"}
+{"text":"A young diamond dealer developed visual impairment attributed to bilateral posterior subcapsular cataracts following only four courses of intermittent Decadron used as part of a five-drug antiemetic regimen for cisplatin-associated nausea.","label":1,"label_text":"Related"}
+{"text":"The mite infestation was not noticed at the time of hospitalization.","label":0,"label_text":"Not-Related"}
+{"text":"This finding is explained by a 'flap-flop phenomenon' where drug absorption is the rate-limiting step of overall drug disposition.","label":0,"label_text":"Not-Related"}
+{"text":"Serious phenytoin hypersensitivity reactions may appear as dermatologic, lymphoid, or hepatic syndromes.","label":1,"label_text":"Related"}
+{"text":"We report a case of biopsy proven myositis whose symptoms began within 10 days of receiving leuprolide acetate therapy for prostate cancer.","label":1,"label_text":"Related"}
+{"text":"Nitrofurantoin-induced pulmonary toxicity during pregnancy: a report of a case and review of the literature.","label":1,"label_text":"Related"}
+{"text":"In both patients, no known etiologic factors, such as systemic lupus erythematosus, poststreptococcal glomerulonephritis, sickle cell anemia, or acquired immunodeficiency syndrome, were evident.","label":0,"label_text":"Not-Related"}
+{"text":"A diagnosis of essential thrombocythemia was made by fulfilling the criteria of the Polycythemia Vera Study Group of the National Cancer Institute.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To describe a patient with ifosfamide-induced nonconvulsive status epilepticus.","label":1,"label_text":"Related"}
+{"text":"Drug-induced linear IgA disease with antibodies to collagen VII.","label":0,"label_text":"Not-Related"}
+{"text":"We describe two patients who developed neurological side effects as part of the spectrum of nitritoid reactions.","label":0,"label_text":"Not-Related"}
+{"text":"The stellate ganglion lies medial to the scalene muscles, lateral to the longus coli muscle, esophagus and trachea along with the recurrent laryngeal nerve, anterior to the transverse processes and prevertebral fascia, superior to the subclavian artery and the posterior aspect of the plura, and posterior to the vertebral vessels at C7 level.","label":0,"label_text":"Not-Related"}
+{"text":"The tinnitus is thought to be secondary to rhythmic involuntary movements of the soft palate.","label":0,"label_text":"Not-Related"}
+{"text":"Continuous ambulatory peritoneal dialysis (CAPD) peritonitis is a common problem in patients on peritoneal dialysis, and the bacteriological diagnosis is important for the treatment of this condition.","label":0,"label_text":"Not-Related"}
+{"text":"In one instance a systemic hypoglycemic reaction resulting in head trauma and confusion ended in an emegency hospital admission following the substitution of acetohexamide for acetazolamide.","label":1,"label_text":"Related"}
+{"text":"Detailed immunological investigation of the patient revealed a severely impaired TH-1 cytokine response as the immunological background for this uncommon course.","label":0,"label_text":"Not-Related"}
+{"text":"A single case of encephalopathy and three cases of peripheral neuropathy are the only neurotoxicities reported.","label":0,"label_text":"Not-Related"}
+{"text":"The authors also determined that their case of myositis developing in the rectus abdominus muscle of a patient with pancreatic adenocarcinoma was the manifestation of radiation recall, thereby bringing the number of patients who developed radiation recall to gemcitabine and were discussed in the current study to 13.","label":1,"label_text":"Related"}
+{"text":"The patient received treatment with dexamethasone 0.2% eyedrops every 2 hours.","label":0,"label_text":"Not-Related"}
+{"text":"Joubert syndrome is a rare autosomal recessive disease characterized by hypotonia, ataxia, episodic hyperpnea, psychomotor retardation, abnormal ocular movements, cerebellar vermian hypoplasia, and molar tooth sign on magnetic resonance imaging.","label":0,"label_text":"Not-Related"}
+{"text":"Nonsteroidal anti-inflammatory agents may be an alternative to chemotherapy and radiotherapy in treating mesenteric desmoids.","label":0,"label_text":"Not-Related"}
+{"text":"Olanzapine may be considered a potential and safer treatment for a this specific group of patients.","label":0,"label_text":"Not-Related"}
+{"text":"After treatment with aripiprazole was started, the patient was inadvertently given an inactive drug, resulting in a worsening of her hemiplegic episodes, which improved again on rechallenge.","label":0,"label_text":"Not-Related"}
+{"text":"The natural history of this condition is resolution without sequelae after appropriate therapeutic intervention for the vena cava thrombosis.","label":0,"label_text":"Not-Related"}
+{"text":"Therefore, fixed drug eruption is a newly observable side effect of this drug.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To draw attention to severe presentations of atypical neuroleptic related diabetes and to document that a marked degree of remission can take place after drug withdrawal.","label":0,"label_text":"Not-Related"}
+{"text":"A case is reported of a 36 y\/o man treated with radiation therapy for cervical cord ependymoma who developed malignant fibrous histiocytoma of the cervical spine 15 years later.","label":0,"label_text":"Not-Related"}
+{"text":"We concluded that flumazenil can antagonize the sedative effects of promethazine at these receptors to return the patient to a wakeful state.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: The anti-natriuretic properties of growth hormone (GH) are well established.","label":0,"label_text":"Not-Related"}
+{"text":"Patient A reported right leg weakness (foot drop) during week 4 of CAP-XRT (1600 mg\/m2).","label":1,"label_text":"Related"}
+{"text":"Atypically, despite high viraemia, serological tests showed persistently negative HBsAg using three different sensitive HBsAg assays (i.e., Architect, Murex and AxSYM).","label":0,"label_text":"Not-Related"}
+{"text":"However, acute cardiomyopathy and pericarditis secondary to methylphenidate use has been rarely reported.","label":1,"label_text":"Related"}
+{"text":"Six of 13 outpatients with schizophrenia who participated in a ten-week open trial of risperidone had an initial good response to the medication followed by development of intolerable affect, including feelings of agitation and depression and periods of crying and insomnia.","label":1,"label_text":"Related"}
+{"text":"She received cyclophosphamide, phenylalanine mustard, urethane, and prednisolone intravenously or orally.","label":0,"label_text":"Not-Related"}
+{"text":"CASE SUMMARY: A 68-year-old woman developed a dry, irritating cough within one month of starting quinapril therapy for the treatment of essential hypertension.","label":1,"label_text":"Related"}
+{"text":"He recovered without sequelae.","label":0,"label_text":"Not-Related"}
+{"text":"Lymphocytes were elevated in bronchoalveolar lavage, and progressively normalized upon discontinuation of the drug.","label":0,"label_text":"Not-Related"}
+{"text":"We report a 44-year-old woman with t-MDS (refractory anemia with excess blasts) following treatment of recurrent anaplastic astrocytoma with temozolomide (TMZ).","label":1,"label_text":"Related"}
+{"text":"OBJECTIVE: To report a case of successful outpatient carboplatin desensitization in a pediatric patient with bilateral optic glioma.","label":0,"label_text":"Not-Related"}
+{"text":"Their parkinsonism improved on discontinuation of metoclopramide therapy.","label":1,"label_text":"Related"}
+{"text":"The cause is presumed to be secondary to hypercoagulability due to asparaginase-induced antithrombin III deficiency.","label":1,"label_text":"Related"}
+{"text":"Three of the patients experienced myalgia and muscle cramps.","label":0,"label_text":"Not-Related"}
+{"text":"Use of glycopyrrolate to treat intraoperative penile erection.","label":0,"label_text":"Not-Related"}
+{"text":"Muzolimine-induced severe neuromyeloencephalopathy: report of seven cases.","label":1,"label_text":"Related"}
+{"text":"Eight weeks later, he experienced pain and redness of the right eye.","label":0,"label_text":"Not-Related"}
+{"text":"Patient was discharged home on postoperative day 19.","label":0,"label_text":"Not-Related"}
+{"text":"At present, no uniformly accepted effective treatment has been described for this condition.","label":0,"label_text":"Not-Related"}
+{"text":"Animals treated with HAL showed a highly significant 32%-46% loss of tyrosine hydroxylase (TH) immunoreactive neurons in the substantia nigra, and 20% contraction of the TH stained dendritic arbour.","label":1,"label_text":"Related"}
+{"text":"Transient left homonymous hemianopsia and encephalopathy following treatment of testicular carcinoma with cisplatinum, vinblastine, and bleomycin.","label":1,"label_text":"Related"}
+{"text":"Since the 3 patients were relatively old (average age, 72 years old) and had various degrees of micro- and macroangiopathies, these side effects may have been associated with increased micro- and macrocirculatory disturbances in their central nervous systems through alpha-glucosidase inhibition of this agent.","label":0,"label_text":"Not-Related"}
+{"text":"The hypoadrenalism was overcome by increasing steroid replacement therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Reactivation of tuberculosis is a complication of its use.","label":0,"label_text":"Not-Related"}
+{"text":"Three days later the patient could say a few single words and extra-ocular movement returned to normal.","label":0,"label_text":"Not-Related"}
+{"text":"Renal failure associated with acetazolamide therapy for glaucoma.","label":1,"label_text":"Related"}
+{"text":"Three hours after the procedure, she had severe headache with vomiting and gradually went into a coma.","label":0,"label_text":"Not-Related"}
+{"text":"A patient receiving long-term corticosteroid therapy for asthma had two episodes of Pneumocystis carinii pneumonia (PCP) 8 years apart.","label":0,"label_text":"Not-Related"}
+{"text":"Sudden reversible vitritis after keratoprosthesis: an immune phenomenon?","label":0,"label_text":"Not-Related"}
+{"text":"All strains were sensitive to linezolid with MIC<4 mg\/l.","label":0,"label_text":"Not-Related"}
+{"text":"The embolization of a venous catheter fragment is a rare complication.","label":0,"label_text":"Not-Related"}
+{"text":"PRCA developed 3 years after the thymectomy and she was successfully treated with cyclosporin.","label":0,"label_text":"Not-Related"}
+{"text":"Ultrasonography of the neck and upper extremity revealed thrombosis of right internal jugular vein.","label":0,"label_text":"Not-Related"}
+{"text":"DISCUSSION: Colchicine, the most important drug in treatment of FMF, can cause myopathy in patients with impaired renal and hepatic function.","label":1,"label_text":"Related"}
+{"text":"An insulin-dependent diabetic patient with nephropathy developed severe acidosis after treatment with acetazolamide for glaucoma.","label":1,"label_text":"Related"}
+{"text":"In patients with diabetes mellitus, hemoglobin A(1c) (A1C) is commonly interpreted as a measure of long-term glycemic control, reflecting a mean glucose level over the previous 2-3 months.","label":0,"label_text":"Not-Related"}
+{"text":"Localized dyskeratotic plaque with milia associated with sorafenib.","label":1,"label_text":"Related"}
+{"text":"Patients with lymphoblastic lymphoma who had treatment with L-asparaginase and steroid are predisposed to the development of cortical venous thrombosis and may have this syndrome in addition to a dural puncture headache.","label":1,"label_text":"Related"}
+{"text":"A study of the intra-cellular cytokines in blood lymphocytes showed a production of IL4 from CD4+ lymphocytes after stimulation by gelatine.","label":0,"label_text":"Not-Related"}
+{"text":"After 3 years of experience with patient reporting, we conclude that patient reporting in spontaneous reporting systems is feasible and that it contributes significantly to a reliable pharmacovigilance.","label":0,"label_text":"Not-Related"}
+{"text":"After 3 months of combination therapy, LAM was stopped and ADV monotherapy was continued.","label":0,"label_text":"Not-Related"}
+{"text":"Lithium and maintenance ECT.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: An objective causality assessment revealed that fluphenazine was the probable cause of NMS in this patient.","label":0,"label_text":"Not-Related"}
+{"text":"We report the successful intraoperative resuscitation of a patient with acute intracardiac\/intravascular thrombosis during an orthotopic liver transplantation using thrombolytic therapy.","label":0,"label_text":"Not-Related"}
+{"text":"She had been administered tacrolimus for prophylaxis of graft-versus-host reaction.","label":0,"label_text":"Not-Related"}
+{"text":"Early treatment of organophosphate (OP) poisoning with oximes results in reactivation of acetylcholinesterase and patient recovery.","label":0,"label_text":"Not-Related"}
+{"text":"Post marketing studies of Interferon-beta (IFN beta) therapy in multiple sclerosis (MS) have demonstrated surprisingly high rates of hepatotoxicity.","label":1,"label_text":"Related"}
+{"text":"There was evidence of extrarenal vascular disease in 12 patients and preexisting renal impairment in 13.","label":0,"label_text":"Not-Related"}
+{"text":"Beneficial late administration of obidoxime in malathion poisoning.","label":0,"label_text":"Not-Related"}
+{"text":"She was found to have PTLD of the nasopharynx.","label":0,"label_text":"Not-Related"}
+{"text":"Patients receiving combination therapy with colchicine and simvastatin, particularly in the presence of renal insufficiency, should be monitored for the development of myopathy, including rhabdomyolysis.","label":0,"label_text":"Not-Related"}
+{"text":"We present a case report of a patient with alveolar hydatid disease, whose treatment with mebendazole was brief due to side effects of alopecia and granulocytopenia; and review the features of this disease which, with increasing international migration, may be encountered more frequently in Australia.","label":1,"label_text":"Related"}
+{"text":"How much do novel antipsychotics benefit the patients?","label":0,"label_text":"Not-Related"}
+{"text":"The DLK in this patient is delayed longer than typically reported in the literature.","label":0,"label_text":"Not-Related"}
+{"text":"The favourable outcome in these two patients contrasts with the fatal outcome of the two other reported cases of nitrofurantoin induced BOOP.","label":1,"label_text":"Related"}
+{"text":"The patient was diagnosed as having a cerebral dural sinus thrombosis, but only after the diagnosis was missed initially.","label":0,"label_text":"Not-Related"}
+{"text":"After 3- to 13-month period of therapy without indapamide, glucose levels of all patients decreased and diabetes disappeared.","label":1,"label_text":"Related"}
+{"text":"METHODS: We describe an 84-year-old patient with breast and colon cancer, who complained of a decrease in visual acuity after treatment with low-dose antiestrogens.","label":0,"label_text":"Not-Related"}
+{"text":"Prehospital diagnosis of massive ethylene glycol poisoning and use of an early antidote.","label":0,"label_text":"Not-Related"}
+{"text":"The patient recovered without permanent sequelae.","label":0,"label_text":"Not-Related"}
+{"text":"We report a 51-year-old male with adult T cell leukemia (ATL) who received a BMT from an HLA-identical unrelated donor.","label":0,"label_text":"Not-Related"}
+{"text":"Child-Pugh class A liver function and a platelet count of > or = 60,000\/mm(3) were among the inclusion criteria for SHARP.","label":0,"label_text":"Not-Related"}
+{"text":"After being seizure-free for at least five years on phenobarbital and carbamazepine, she experienced seizures related to the product change.","label":0,"label_text":"Not-Related"}
+{"text":"Her symptoms and pulmonary nodules resolved following treatment with corticosteroids.","label":0,"label_text":"Not-Related"}
+{"text":"Despite the underlying hepatitis C, this case represents renal abnormalities consistent with IFNalpha therapy for CML.","label":1,"label_text":"Related"}
+{"text":"The administration of phenobarbital in this patient allowed improved symptom control, minimized the potential for propylene glycol toxicity, was not associated with respiratory depression, and facilitated successful weaning of benzodiazepines.","label":0,"label_text":"Not-Related"}
+{"text":"Papilloedema and hepatic dysfunction apparently induced by perhexiline maleate (Pexid).","label":1,"label_text":"Related"}
+{"text":"Minor electrocardiographical changes were noted in five out of six patients who were not receiving a cardiac glycoside and four out of six who were receiving ouabain, and none of the 16 who were receiving digoxin.","label":1,"label_text":"Related"}
+{"text":"CASE SUMMARY: A 54-year-old white man received a heart transplant secondary to ischemic dilated cardiomyopathy.","label":0,"label_text":"Not-Related"}
+{"text":"Within one month the corneal ulcer and infiltration disappeared.","label":0,"label_text":"Not-Related"}
+{"text":"A purple rash in the left submandibular area was noted.","label":0,"label_text":"Not-Related"}
+{"text":"Therefore, ACE inhibitors should be discouraged for the majority of patients with primary aldosteronism, even in the face of renal or cardiac disease.","label":0,"label_text":"Not-Related"}
+{"text":"CASE SUMMARIES: Three severely agitated patients in ICU did not respond to conventional therapy with opiates, benzodiazepines, and intermittent intravenous doses of haloperidol.","label":0,"label_text":"Not-Related"}
+{"text":"It is considered to be an organism with a limited pathogenic potential, which is rarely capable of causing diseases in humans other than in those who are in an immunocompromised state.","label":0,"label_text":"Not-Related"}
+{"text":"After implementation of additional preventative safeguards, no further errors or complications have occurred.","label":0,"label_text":"Not-Related"}
+{"text":"This case report describes a patient who was previously prescribed alendronate (Fosamax) and presented with postoperative hypophosphatemia and hypocalcemic tetany after bowel preparation with Fleet Phospho-Soda.","label":1,"label_text":"Related"}
+{"text":"Group B streptococcal late-onset sepsis with submandibular phlegmon in a premature infant after beginning of breast-feeding.","label":0,"label_text":"Not-Related"}
+{"text":"This side effect has only once previously been reported with the nitrosourea group of compounds.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Ethambutol, and to a lesser extent isoniazid, are both implicated in the development of visually related side effects.","label":1,"label_text":"Related"}
+{"text":"We describe the development of ischemic colitis in a woman who was treated with tegaserod and review the relationship among ischemic colitis, tegaserod use, and irritable bowel syndrome.","label":1,"label_text":"Related"}
+{"text":"The subintensive supervision consisted of instrumental monitoring with the assistance of an intensive care anesthetist.","label":0,"label_text":"Not-Related"}
+{"text":"AIM: The aim of this article is to present the clinical characteristics and management of an oral adverse effect stemming from the use of the antiretroviral medication Nevirapine (NVP).","label":0,"label_text":"Not-Related"}
+{"text":"With this therapy left ventricular function improved and CHF resolved in each.","label":0,"label_text":"Not-Related"}
+{"text":"Akathisia is generally considered to result from D2 dopamine receptor antagonism.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: We present a detailed case report, review the related literature, and suggest the need for prospective studies to determine the appropriate intervention in critically ill patients with pseudo-Cushing's syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"The former patient had complained once that his visual acuity had decreased after the termination of IFN therapy, and the latter patient complained twice during IFN therapy that his visual acuity had decreased.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: Among the many presentations of ifosfamide neurotoxicity, clinicians should consider NCSE as a possible explanation for changes in consciousness in a patient receiving this agent.","label":1,"label_text":"Related"}
+{"text":"He also suffered from acute stroke, and brain magnetic resonance angiography showed total left internal carotid artery occlusion.","label":0,"label_text":"Not-Related"}
+{"text":"One patient with blebitis progressed to culture-positive endophthalmitis.","label":0,"label_text":"Not-Related"}
+{"text":"In patients with an impaired renal function, AZ should therefore be administered very carefully in order to avoid an accumulation of the drug.","label":0,"label_text":"Not-Related"}
+{"text":"She remains cough-free to date.","label":0,"label_text":"Not-Related"}
+{"text":"Although major hazards of treatment of hypophosphatemic osteomalacia with phosphate and calcitriol are secondary hyperparathyroidism and vitamin D intoxication, potassium loss also should be kept in mind.","label":1,"label_text":"Related"}
+{"text":"Early diagnosis and prompt surgical treatment are the keys to success in the treatment of this limb-threatening complication.","label":0,"label_text":"Not-Related"}
+{"text":"Here, we report the cases of two children who developed typical clinical and biochemical features of BMTN.","label":0,"label_text":"Not-Related"}
+{"text":"Infliximab, a chimeric monoclonal antibody targeting tumor necrosis factor alpha (TNF-alpha), is efficacious in the treatment of rheumatoid arthritis and Crohn's disease.","label":0,"label_text":"Not-Related"}
+{"text":"A report is presented of a patient who developed multiple abscesses of the pancreas due to Candida albicans following an Endoscopic retrograde chole-pancreatography (ERCP) for acute pancreatitis.","label":0,"label_text":"Not-Related"}
+{"text":"The patient presented with several actinic keratoses, squamous cell carcinomas, and multiple keratoacanthomas, one of which was pigmented.","label":0,"label_text":"Not-Related"}
+{"text":"Reye-like syndrome following treatment with the pantothenic acid antagonist, calcium hopantenate.","label":1,"label_text":"Related"}
+{"text":"Risks regarding disseminated intravascular coagulation and bleeding were presented to the parents.","label":0,"label_text":"Not-Related"}
+{"text":"Molluscum contagiosum lesions are presumably common in IRIS but underreported.","label":0,"label_text":"Not-Related"}
+{"text":"Serial respiratory function tests in patients receiving bimodal therapy may facilitate early diagnosis of this potentially serious complication.","label":0,"label_text":"Not-Related"}
+{"text":"Severe psoriasis is commonly associated with depression and may be its cause.","label":0,"label_text":"Not-Related"}
+{"text":"Therefore, both patients received repeated courses of rituximab, an anti-CD20 monoclonal antibody, in combination with irradiated DLI.","label":0,"label_text":"Not-Related"}
+{"text":"Leukemia was treated with courses of adriblastin, cytosine arabinoside, and thioguanin (DAT protocol), with a 8 months' survival.","label":0,"label_text":"Not-Related"}
+{"text":"We describe 3 elderly patients with moderate to severe ataxia that occurred while they were taking propafenone.","label":1,"label_text":"Related"}
+{"text":"Although a neurological evaluation by a neurosurgeon could suggest the presence of a vague cerebellar sign, neuro-otological evaluation disclosed diverse abnormal findings which clearly demonstrated the presence of dysfunction in the cerebellar system, especially of the verminal and flocculonodular lobe lesion.","label":0,"label_text":"Not-Related"}
+{"text":"In two of these cases akathisia resolved after withdrawal of olanzapine and substitution by a classical or an atypical neuroleptic agent, respectively.","label":1,"label_text":"Related"}
+{"text":"Severe disease activity and complications of immunosuppressive therapy: a challenge for acute hospital-based rehabilitation in rheumatology.","label":0,"label_text":"Not-Related"}
+{"text":"The authors postulate that two types of combined lithium-neuroleptic toxicity occur: a neuroleptic malignant extrapyramidal syndrome and a lithium toxicity that occurs in combination with phenothiazines, primarily thioridazine.","label":1,"label_text":"Related"}
+{"text":"With the use of optical coherence tomography (OCT), two patients with IFN-associated retinopathy who had developed macular edema and reduced visual acuity during the clinical course of IFN therapy were observed.","label":1,"label_text":"Related"}
+{"text":"Endoscopy showed a normal colon, histopathology of random biopsies of all sections of the colon demonstrated the characteristic features of collagenous colitis.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of a patient with chronic lymphocytic leukemia (CLL) who developed fatal intravascular autoimmune hemolytic anemia (AIHA) after fludarabine treatment.","label":1,"label_text":"Related"}
+{"text":"The study was closed early for safety reasons as there were three unexpected treatment-related deaths.","label":0,"label_text":"Not-Related"}
+{"text":"Histopathologic study of the ecthyma gangrenosum-like lesion, as well as pustular lesions, revealed epidermal necrosis and an inflammatory infiltrate in the upper dermis, with numerous septate hyphae demonstrated by periodic acid-Schiff stain.","label":0,"label_text":"Not-Related"}
+{"text":"Discontinuation of the itraconazole caused resolution of the drug eruption.","label":1,"label_text":"Related"}
+{"text":"We present a case of severe unilateral posterior scleritis associated with zoledronic acid administration that was recognized and treated in a timely manner.","label":1,"label_text":"Related"}
+{"text":"Over the next few days, signs and symptoms of hepatotoxicity progressed, and she became comatose.","label":0,"label_text":"Not-Related"}
+{"text":"He admitted to our hospital and tricuspid valve endocarditis was proved by echocardiography.","label":0,"label_text":"Not-Related"}
+{"text":"A case is described of severe splenic hemorrhage and rupture which developed 3 h after completion of tPA infusion for suspected acute myocardial infarction.","label":1,"label_text":"Related"}
+{"text":"The patient rapidly responded to intravenous ampicillin.","label":0,"label_text":"Not-Related"}
+{"text":"Low-dose oral methotrexate treatment for recalcitrant palmoplantar pompholyx.","label":0,"label_text":"Not-Related"}
+{"text":"Mesalamine-induced hypersensitivity pneumonitis.","label":1,"label_text":"Related"}
+{"text":"Several possible explanations of the mechanism of renal failure associated with the use of dextran-40 are discussed.","label":1,"label_text":"Related"}
+{"text":"Therefore, amantadine was permanently discontinued and the cornea cleared again.","label":1,"label_text":"Related"}
+{"text":"The patients developed uveitis, sometimes in combination with a transient rash, arthralgia, arthritis, jaundice and pseudojaundice.","label":0,"label_text":"Not-Related"}
+{"text":"Behavioural changes were not related to seizure activity.","label":0,"label_text":"Not-Related"}
+{"text":"There were 15 (55%) patients that responded, three with a complete and 12 with a partial response with a mean duration of response of 13.4 months.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case in a teenage female recently started on oral contraception.","label":0,"label_text":"Not-Related"}
+{"text":"His immunosuppressive medication had been tapered to 15 mg\/day of prednisolone.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Of the 18 patients treated with MMF, there were 11 men (61.1%) and seven women (38.8%), with an overall mean age of 55.5 years.","label":0,"label_text":"Not-Related"}
+{"text":"Clinical experience with Chymopapain casts doubts upon the reported results of the limited double blind studies done mainly by surgeons and their residents, relatively inexperienced in the disc injection technique.","label":0,"label_text":"Not-Related"}
+{"text":"Complete lysis of the thrombus was observed after 6 months of treatment with UFH and LMWH respectively without any further complications.","label":0,"label_text":"Not-Related"}
+{"text":"INTRODUCTION: We describe the neurointensive care (NIC) management of a patient with severe cerebral swelling and raised intracranial pressure (ICP) after severe sodium valproic acid (VPA) intoxication.","label":1,"label_text":"Related"}
+{"text":"Disulfiram-induced fulminant hepatic failure in an active duty soldier.","label":1,"label_text":"Related"}
+{"text":"These organisms are, however, sensitive to vancomycin.","label":0,"label_text":"Not-Related"}
+{"text":"She developed skin changes, diabetes mellitus, heart disease, recurrent infections, generalized joint and abdominal pains and liver failure.","label":0,"label_text":"Not-Related"}
+{"text":"A case of propranolol overdose complicated by esophageal spasm preventing extrication of an orogastric lavage tube and relieved by intravenous glucagon is presented.","label":1,"label_text":"Related"}
+{"text":"Amiodarone was discontinued, and thyrotoxicosis gradually abated.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: An antidepressant which has been effective for as long as 7 years may still carry risk of inducing agitated dysphoria, even in apparently unipolar depression.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Acute severe hepatitis though rare is occasionally observed with EGFR inhibitors gefitinib or erlotinib.","label":1,"label_text":"Related"}
+{"text":"In order to achieve complete anticoagulation, patients were switched to bivalirudin, which determined a prompt effect on measured ACT.","label":0,"label_text":"Not-Related"}
+{"text":"Analysis of the literature on scrofuloderma between 1978-1993 disclosed that the number of cases with extracervical involvement are increasing.","label":0,"label_text":"Not-Related"}
+{"text":"In order for him to receive the needed chemotherapy, we developed a desensitization protocol that was administered in the intensive care unit.","label":0,"label_text":"Not-Related"}
+{"text":"An unusual case of necrotizing fasciitis with extensive soft tissue infection stemming from a prolonged case of osteonecrosis of the jaw presented.","label":0,"label_text":"Not-Related"}
+{"text":"A 78-year-old man with severe chronic obstructive pulmonary disease presented to our pain medicine clinic for treatment of post herpetic neuralgia.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of successful management of iatrogenic intravitreal triamcinolone acetonide for intermediate uveitis.","label":0,"label_text":"Not-Related"}
+{"text":"We highlight two instances of systemic allergic reaction, and discuss the potential side effects of local aprotinin injections in the orthopaedic setting as well as the evidence base for its use.","label":1,"label_text":"Related"}
+{"text":"We report liver biopsy findings in a follow-up biopsy of a patient who had been switched from azathioprine to mycophenolate mofetil for treatment of presumed, steroid-responsive autoimmune hepatitis.","label":0,"label_text":"Not-Related"}
+{"text":"DiGeorge's syndrome in monozygotic twins.","label":0,"label_text":"Not-Related"}
+{"text":"We report here the successful use of ONSF to restore vision to three consecutive patients with pending anterior RION, and the importance of early identification and intervention in these potentially reversible cases.","label":0,"label_text":"Not-Related"}
+{"text":"Primary biliary cirrhosis and polymyositis.","label":0,"label_text":"Not-Related"}
+{"text":"A 55-year-old male patient with hepatitis B-related liver cirrhosis was found to have advanced hepatocellular carcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"Chest x-ray and computed tomography revealed multiple patchy infiltrates in both cases; after several days, these confluent infiltrates developed into pneumatoceles.","label":0,"label_text":"Not-Related"}
+{"text":"Abnormal metabolism of valproic acid in fatal hepatic failure.","label":0,"label_text":"Not-Related"}
+{"text":"A prospective controlled trial comparing the treatment effects of psychostimulants and donepezil on patients having opioid-induced sedation is underway.","label":0,"label_text":"Not-Related"}
+{"text":"Rifampicin, an antituberculous drug, causes increased hepatic metabolism of steroid hormones.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To report 2 cases of serotonin syndrome with serious extrapyramidal movement disorders occurring when metoclopramide was coadministered with sertraline or venlafaxine.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: Cicatrization in the substantia propria of the conjunctiva by excessive lymphocytic infiltration after topically administered antiglaucoma drugs including dipivefrin is a possible mechanism of action for entropion.","label":1,"label_text":"Related"}
+{"text":"We have observed an increasing number of autopsies on patients with chemotherapy-related complications.","label":0,"label_text":"Not-Related"}
+{"text":"Toxicology testing confirmed the presence of strychnine in blood, gastric aspirate, and urine.","label":0,"label_text":"Not-Related"}
+{"text":"We present the case of a 5-year-old girl who developed bilateral vocal cord paralysis following preoperative peritonsillar bupivacaine infiltration.","label":1,"label_text":"Related"}
+{"text":"Patients should be injury advised to seek prompt ophthalmic consultation after LASIK.","label":0,"label_text":"Not-Related"}
+{"text":"Hemodialysis was shown to remove ifosfamide, chloroacetaldehyde, and 4-hydroxyifosfamide from the blood stream.","label":0,"label_text":"Not-Related"}
+{"text":"In this case, CIPS was considered to be probably associated with cyclosporine according to the Naranjo probability scale.","label":1,"label_text":"Related"}
+{"text":"Histology showed foci of dyskeratosis in the mucosal layer and a polymorphic perivascular inflammatory infiltrate of the papillary dermis, suggesting a drug-induced skin reaction.","label":0,"label_text":"Not-Related"}
+{"text":"Post-allogeneic BMT complications include graft-versus-host disease (GVHD).","label":0,"label_text":"Not-Related"}
+{"text":"Fluid volume expands with a resultant hyponatremia which, depending on the degree, may be asymptomatic or result in death.","label":0,"label_text":"Not-Related"}
+{"text":"We report on a case of a female patient with a chronic schizoaffective psychosis, who was treated for 3 months with 3 x 3 mio IE IFN-alpha s.c.\/week because of a chronic hepatitis C (genotype 1b).","label":0,"label_text":"Not-Related"}
+{"text":"Methylphenidate and dextroamphetamine are central nervous system stimulants used in the treatment of attention deficit hyperactivity disorders in children.","label":0,"label_text":"Not-Related"}
+{"text":"All of the cats were hyperglycemic for most of the day.","label":0,"label_text":"Not-Related"}
+{"text":"Churg-Strauss disease (CSD) is a rare allergic disorder that is associated with vasculitis, peripheral eosinophilia and allergic asthma.","label":0,"label_text":"Not-Related"}
+{"text":"Despite satisfactory hemodynamic measurements under general anesthesia, we postulated that she suffered from increased pulmonary vascular reactivity and commenced her on Sildenafil treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Unlike the persistently elevated serum HBV DNA level, the serum ALT and AST levels have gradually decreased.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of Ritalin-associated cataract and glaucoma.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND: Hemangiomas pose a therapeutic challenge because they can threaten vision in infancy and early childhood.","label":0,"label_text":"Not-Related"}
+{"text":"Corneal edema resolved completely after 2 weeks, although reduced endothelial cell count and abnormal morphology persisted.","label":0,"label_text":"Not-Related"}
+{"text":"The fetal valproate syndrome (FVS) is characterized by distinctive facial appearance, major and minor malformations, and developmental delay.","label":1,"label_text":"Related"}
+{"text":"Cryoglobulinemic MPGN was suspected and kidney biopsy was performed, resulting in a diagnosis of minimal change disease (MCD).","label":0,"label_text":"Not-Related"}
+{"text":"The other patient had locally advanced anal carcinoma and received concurrent 5-fluorouracil, mitomycin, and radiation therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Transient obstruction of the mitral valve by a massive thrombus complicating percutaneous valvuloplasty.","label":0,"label_text":"Not-Related"}
+{"text":"Mirtazapine had been started 8 days earlier to control major depression.","label":0,"label_text":"Not-Related"}
+{"text":"Milk-alkali syndrome was first described 70 years ago in the context of the treatment of peptic ulcer disease with large amounts of calcium and alkali.","label":0,"label_text":"Not-Related"}
+{"text":"Liver toxicity, although not mentioned among the possible adverse effects of corticosteroids, has been occasionally reported in literature.","label":0,"label_text":"Not-Related"}
+{"text":"Cis-retinoic acid (RA) may further increase the risk of developing BMTN.","label":1,"label_text":"Related"}
+{"text":"Six weeks after withdrawal of the antituberculosis drugs and conservative management, the boy was clinically well and ten months later he remained well clinically and liver function tests, anti-DNA antibody and antinuclear factor tests were normal.","label":0,"label_text":"Not-Related"}
+{"text":"A case is reported of a true monocytic leukemoid reaction in a patient with myelodysplastic syndrome related to the effect of corticosteroids on the underlying marrow disorder.","label":0,"label_text":"Not-Related"}
+{"text":"A sixty-year-old woman with advanced breast cancer, previously treated with cisplatin, developed an irreversible lethal renal failure with anuria, the day after 5 g\/m2 bolus ifosfamide.","label":1,"label_text":"Related"}
+{"text":"His arthritis remained quiescent while taking the drug and following its withdrawal his condition relapsed and his serum IgA level returned to normal.","label":0,"label_text":"Not-Related"}
+{"text":"SSTR2A was also expressed in lymphocytes that had infiltrated thyroid tissue in Hashimoto's thyroiditis.","label":0,"label_text":"Not-Related"}
+{"text":"One week after the surgery, the patient developed a corneoscleral perforation with iris prolapse.","label":0,"label_text":"Not-Related"}
+{"text":"Reversal of severe methanol-induced visual impairment: no evidence of retinal toxicity due to fomepizole.","label":1,"label_text":"Related"}
+{"text":"Electromyographic investigation revealed a myopathic pattern in proximal muscles without any neuropathic changes.","label":0,"label_text":"Not-Related"}
+{"text":"The total amount ingested range from 14.3 to 99.3 mg\/kg (mean, 54 mg\/kg).","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of children with refractory acute lymphocytic leukemia with vincristine and diltiazem.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of BK virus-associated nephropathy with Cidofovir in renal transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: The records of all five diabetic aircrew were reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"Exacerbations of the heart failure were temporally related to the administration of the antitumor antibiotics actinomycin-D (NSC-3053) and mithramycin (NSC-24559).","label":1,"label_text":"Related"}
+{"text":"We report on a patient with a high grade B-cell lymphoma who presented 28 days after the second autologous stem cell transplantation with weight gain, ascites, hyperbilirubinemia, and liver venules occlusion as demonstrated by sonography.","label":0,"label_text":"Not-Related"}
+{"text":"Abdominal ultrasound was normal with the exception of a slight hepatomegaly without any lesions, focal or diffuse.","label":0,"label_text":"Not-Related"}
+{"text":"MANAGEMENT: Intravenous dobutamine and dopamine for cardiogenic shock and discontinuation of interferon alpha-2b.","label":0,"label_text":"Not-Related"}
+{"text":"A high dose of cotrimoxazole induced hyperkalaemia with the elevation of serum creatinine and blood urea, and increased urinary N-acetyl glucosaminase after several days of the drug administration in these patients; one patient became unconscious.","label":1,"label_text":"Related"}
+{"text":"The treatment of visceral leishmaniasis (VL) may be complicated by drug toxicity or intolerance, and by drug resistance.","label":0,"label_text":"Not-Related"}
+{"text":"Here, we report another such case.","label":0,"label_text":"Not-Related"}
+{"text":"Presented is a case story of a woman with classical rheumatoid arthritis, who during introduction of sulphasalazine (SASP) therapy developed a severe and lasting psoriasis-like skin reaction.","label":1,"label_text":"Related"}
+{"text":"Although various manifestations of pentamidine-induced cardiotoxicity have been reported, to our knowledge, second-degree heart block associated with this agent has not been described.","label":1,"label_text":"Related"}
+{"text":"Treatment with itraconazole of widespread tinea corporis due to Trichophyton rubrum in a bone marrow transplant recipient.","label":0,"label_text":"Not-Related"}
+{"text":"Drug-induced rhabdomyolysis during pregnancy is extremely rare.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of alternating hemiplegia of childhood with aripiprazole.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Nocardia exalbida was first reported in 2006.","label":0,"label_text":"Not-Related"}
+{"text":"Psoriatic arthritis complicating lung cancer.","label":0,"label_text":"Not-Related"}
+{"text":"Congenital cytomegalovirus (CMV) infection occurs in approximately 1% of newborns and is the leading infectious cause of congenital birth defects.","label":0,"label_text":"Not-Related"}
+{"text":"Systemic lupus erythematosus: association with psoralen--ultraviolet-A treatment of psoriasis.","label":0,"label_text":"Not-Related"}
+{"text":"A patient suffering from heparin-associated thrombocytopenia (HAT), recurrent arteriothromboses, and acute renal failure after treatment with standard heparin is described.","label":1,"label_text":"Related"}
+{"text":"We present an unusual case of verified myocardial infarction without surgery.","label":0,"label_text":"Not-Related"}
+{"text":"We report the first case of rhabdomyolysis related to the administration of clarithromycin without concurrent use of other medications.","label":1,"label_text":"Related"}
+{"text":"Drug-induced iatrogenic lung disease.","label":0,"label_text":"Not-Related"}
+{"text":"Prior cases are reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"Osteonecrosis is a feared complication of corticosteroid use.","label":0,"label_text":"Not-Related"}
+{"text":"A 57-year-old man developed chronic, watery diarrhea four weeks after Helicobacter pylori eradication therapy including lansoprazole followed by lansoprazole monotherapy for gastroesophageal reflux disease.","label":1,"label_text":"Related"}
+{"text":"DISCUSSION: Because of the close time relationship between drug administration and the development of symptoms and signs, as well as between drug withdrawal and changes in WBC count and ANC, the episodes of neutropenia were suspected to be drug related.","label":0,"label_text":"Not-Related"}
+{"text":"Myoglobinuria and acute renal failure associated with intravenous vasopressin infusion.","label":1,"label_text":"Related"}
+{"text":"Today hairy leukoplakia has come to represent a sign of immunosuppression and not just of HIV infection.","label":0,"label_text":"Not-Related"}
+{"text":"Multiple seizures after bupropion overdose in a small child.","label":1,"label_text":"Related"}
+{"text":"A 21-year-old woman developed epilepsy, disturbance of mental state, and spastic tetraparesis during the convalescent period after acute viral encephalitis.","label":0,"label_text":"Not-Related"}
+{"text":"The eruption cleared on withdrawal of the drug.","label":0,"label_text":"Not-Related"}
+{"text":"A biopsy was performed and evidence from light microscopic analysis of the tissue led to a diagnosis of TEN.","label":0,"label_text":"Not-Related"}
+{"text":"She was diagnosed with Epstein-Barr virus-associated polymorphic lymphoproliferative disorder (LPD) due to immunodeficiency caused by MTX administration.","label":1,"label_text":"Related"}
+{"text":"The patient may have concomitant systemic disease, and the injury occurs with relatively mild trauma.","label":0,"label_text":"Not-Related"}
+{"text":"Carbamazepine toxicity following Oxybutynin and Dantrolene administration: a case report.","label":1,"label_text":"Related"}
+{"text":"A 52 year-old male patient diagnosed of ankylosing spondylitis presented with an iron deficiency anemia after a ten-month treatment of methotrexate.","label":1,"label_text":"Related"}
+{"text":"Pulmonary fibrosis subsequent to high doses of CCNU for chronic myeloid leukemia.","label":1,"label_text":"Related"}
+{"text":"Fever, rash, and lymphadenopathy often accompany hepatic injury.","label":0,"label_text":"Not-Related"}
+{"text":"We remind clinicians that phenytoin toxicity can easily mimic a cerebellar lesion or alcohol intoxication, and suggest that in accordance with National Institute for Clinical Excellence (NICE) guidelines phenytoin should no longer be used as a first-line treatment for epilepsy.","label":0,"label_text":"Not-Related"}
+{"text":"CASE SUMMARY: A 16-day-old infant developed several mild episodes of apnea that culminated in a severe cyanotic episode requiring resuscitation.","label":0,"label_text":"Not-Related"}
+{"text":"However, repeated intracameral tPA injections may cause unwanted complications such as vitreous hemorrhage.","label":1,"label_text":"Related"}
+{"text":"Mono-octanoin (glycerol-1-mono-octanoate) is a medium-chain diglyceride used to dissolve gallstones.","label":0,"label_text":"Not-Related"}
+{"text":"Fatal interstitial pneumonitis following high-dose intermittent chlorambucil therapy for chronic lymphocyte leukemia.","label":1,"label_text":"Related"}
+{"text":"The cause of the cerebrospinal fluid leak and different treatment approaches are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"Vaccination as a triggering event for autoimmune hepatitis.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients with ovarian cancer who had received multiple courses of cisplatin without complications experienced hypersensitivity reactions to cisplatin: one, involving intrahepatic artery infusion, manifested general erythema, dyspnea, and hypotension; the other, involving intravenous infusion, manifested abdominal pain, general erythema, and fever.","label":1,"label_text":"Related"}
+{"text":"In contrast to the symptoms during monotherapy with IFN-alpha, during the time of both combination treatments, no psychiatric side effects occurred.","label":0,"label_text":"Not-Related"}
+{"text":"However, little is known about this complication immediately after vertebral artery stenting.","label":0,"label_text":"Not-Related"}
+{"text":"SETTING: Intensive care unit of a tertiary care hospital.","label":0,"label_text":"Not-Related"}
+{"text":"Rescue of haemopoiesis by a combination of growth factors including stem-cell factor.","label":0,"label_text":"Not-Related"}
+{"text":"Diabetes Mellitus was observed in a patient given carbamazepine.","label":1,"label_text":"Related"}
+{"text":"To our knowledge, these cases are the first published reports of lovastatin-induced rhabdomyolysis associated with azithromycin and clarithromycin.","label":1,"label_text":"Related"}
+{"text":"Patient 1 developed squamous cell carcinoma of the skin with recurrence, and Patient 2 developed anaplastic carcinoma of the urinary bladder.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: The patient was treated with an ICP-guided protocol including mild hyperventilation, normovolemia, head elevation and intermittent doses of mannitol.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of a 27-year-old Indian woman who developed maculopapular rash and angioedema secondary to carbamazepine administration.","label":1,"label_text":"Related"}
+{"text":"When the acute manic state is characterized by marked psychotic symptoms and intense anxiety, it may be associated with increased vulnerability to the development of severe lithium neurotoxicity.","label":1,"label_text":"Related"}
+{"text":"Five days after the fourth dose of vincristine, she presented with bilateral ptosis.","label":1,"label_text":"Related"}
+{"text":"We present a case in which a bolus intravenous injection of sulprostone 30 micrograms was administered to treat postpartum haemorrhage during caesarean section.","label":0,"label_text":"Not-Related"}
+{"text":"This case highlights the potential danger of high dose vitamin supplements in children, and the salutary effects of treatment with bisphosphonate.","label":0,"label_text":"Not-Related"}
+{"text":"A clinical and microbiologic response occurred when anticoagulation therapy with heparin was added to the treatment regimen.","label":0,"label_text":"Not-Related"}
+{"text":"CSF examination revealed an inflammatory profile.","label":0,"label_text":"Not-Related"}
+{"text":"Vitamin D, whose primary action is to facilitate intestinal absorption of calcium, may also be a hormone of prime necessity in infant bone formation.","label":0,"label_text":"Not-Related"}
+{"text":"The other patient presented with typical cutaneous polyarteritis nodosa which responded well to corticosteroid treatment.","label":0,"label_text":"Not-Related"}
+{"text":"He developed a foreign-body sensation and persistent superotemporal corneal erosion as a result fo an adrenochrome deposit on the upper tarsus.","label":0,"label_text":"Not-Related"}
+{"text":"We made the diagnosis of acute gouty arthritis arising from tumor lysis and liver infarction caused by HCC ablation, which was aggravated by acute renal insufficiency.","label":0,"label_text":"Not-Related"}
+{"text":"Aluminum intoxication, along with other factors, was considered to be the cause of TC development.","label":1,"label_text":"Related"}
+{"text":"There is a dose-effect relationship between doxorubicin and the incidence of symptomatic cardiac failure.","label":1,"label_text":"Related"}
+{"text":"Oral etoposide remains an effective palliative agent and its usage should not be excluded without most careful consideration of the risks.","label":0,"label_text":"Not-Related"}
+{"text":"Nosocomial malaria and saline flush.","label":0,"label_text":"Not-Related"}
+{"text":"A 33-year-old man with a history of recreational benztropine abuse presented to the emergency department with confusion, abdominal pain, and distention.","label":1,"label_text":"Related"}
+{"text":"Her clinical status improved with urgent thrombolytic therapy (with tisokinase and urokinase) and anticoagulation therapy (with heparin and warfarin), and her life was saved.","label":0,"label_text":"Not-Related"}
+{"text":"Refractory pouchitis developed in all patients as well as protracted symptoms of diarrhea, abdominal pain, joint pain, and incontinence.","label":0,"label_text":"Not-Related"}
+{"text":"In four of five children who took the drug as scheduled, a cytolytic effect was observed.","label":0,"label_text":"Not-Related"}
+{"text":"Conversely, bile reflux and nitrite and N-nitrous compounds caused by abnormal bacterial growth in the gastric stump may play a role in inducing mucosa-associated lymphoid tissue lymphoma.","label":0,"label_text":"Not-Related"}
+{"text":"Fundoscopic examination revealed only hypertensive retinopathy.","label":0,"label_text":"Not-Related"}
+{"text":"After the first oral dose of propranolol, syncope developed together with atrioventricular block.","label":1,"label_text":"Related"}
+{"text":"In children, only a few cases with this complication have been reported.","label":0,"label_text":"Not-Related"}
+{"text":"Acute respiratory distress related to chemotherapy of advanced pulmonary tuberculosis: a study of two cases and review of the literature.","label":0,"label_text":"Not-Related"}
+{"text":"These findings support recent evidence identifying TNF-alpha as an inhibitor of autoantibody formation.","label":0,"label_text":"Not-Related"}
+{"text":"The only possible seizure-provoking factors were modest doses of lithium and chlorpromazine, which the patient was on, and family history of seizure in a brother.","label":0,"label_text":"Not-Related"}
+{"text":"The admission computed tomography scan of the chest revealed progressive interstitial infiltrates.","label":0,"label_text":"Not-Related"}
+{"text":"Despite aggressive therapy with amphotericin B, the neonate succumbed to overwhelming systemic candidiasis.","label":0,"label_text":"Not-Related"}
+{"text":"Differences in susceptibility may exist if either the criteria for either Pseudomonas or Enterobacteriaceae are used.","label":0,"label_text":"Not-Related"}
+{"text":"Though hypotension, dry mouth, and constipation are well-documented possible adverse effects, the possibility of clonidine-induced bradycardia is less well recognized and is rare.","label":1,"label_text":"Related"}
+{"text":"He was taken to the emergency department and given intravenous methylprednisolone sodium succinate and intravenous diphenhydramine hydrochloride.","label":0,"label_text":"Not-Related"}
+{"text":"Thrombocytosis associated with enoxaparin: A very rare cause in newborns.","label":1,"label_text":"Related"}
+{"text":"This complication typically appears within the first days or weeks after initiation of therapy.","label":0,"label_text":"Not-Related"}
+{"text":"CLINICAL PICTURE: A 60-year-old Indonesian male presented initially with fever, acute confusion and rapidly progressive right upper lobe pneumonia 3.5 months post-liver transplant, and was diagnosed with pulmonary tuberculosis by positive sputum smear for acid-fast bacilli and tuberculosis culture.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: All 4 high-risk corneal transplant patients experienced episodes of acute rejection that was successfully reversed with topical tacrolimus treatment.","label":0,"label_text":"Not-Related"}
+{"text":"An obese 53-year-old woman (height 167 cm, weight 130 kg) with metastatic breast cancer received high-dose chemotherapy comprising cyclophosphamide, thiotepa and carboplatin (CTC).","label":0,"label_text":"Not-Related"}
+{"text":"High dose corticosteroids have been the mainstay in the treatment of fulminant ulcerative colitis (UC) for a long time.","label":0,"label_text":"Not-Related"}
+{"text":"If confirmed, this observation may open new possibilities in intensive chemotherapy for patients for whom haematopoietic progenitors are difficult to harvest.","label":0,"label_text":"Not-Related"}
+{"text":"The reversible posterior leukoencephalopathy syndrome (RPLES) is a condition characterised by reversible neurological and radiological findings that has been associated with use of immunosuppressive, chemotherapeutic and more recently novel targeted therapies.","label":0,"label_text":"Not-Related"}
+{"text":"We report treatment of a 38-year-old man with minimal change disease (MCD) who developed pneumatosis intestinalis (PI) during administration of immune-suppressive agents.","label":0,"label_text":"Not-Related"}
+{"text":"Since recent studies have reported no negative interactions with concurrent use, we here report three cases (one case of a prolonged seizure, a serotonin syndrome and a focal seizure) of severe lithium-induced side effects while patients underwent ECT without complications and lithium serum levels were still subtherapeutic.","label":1,"label_text":"Related"}
+{"text":"Nephrotic range pseudoproteinuria in a tolmetin-treated patient.","label":1,"label_text":"Related"}
+{"text":"This sulfonamide like nephropathy should be differentiated from acetazolamide-related calcium phosphate nephrolithiasis.","label":1,"label_text":"Related"}
+{"text":"Three such patients are described whose main features were uncontrolled seizures, progressive dementia, behaviour disorder, muscular pseudohypertrophy, and a relative paucity of localizing neurological signs or signs of raised intracranial pressure.","label":0,"label_text":"Not-Related"}
+{"text":"Physicians should be aware of the potential for the development of RS among children who are receiving long-term aspirin therapy for the treatment of systemic inflammatory illnesses.","label":1,"label_text":"Related"}
+{"text":"In the following case report, a patient developed acute interstitial nephritis with renal failure and exfoliative dermatitis following ampicillin therapy.","label":1,"label_text":"Related"}
+{"text":"To date little has been reported about the risk of therapy-related leukaemia (t-AML) in children receiving oral etoposide therapy.","label":0,"label_text":"Not-Related"}
+{"text":"A sweat test using pilocarpine iontophoresis revealed a marked reduction in the sweat response, which suggested a postganglionic sweating dysfunction.","label":0,"label_text":"Not-Related"}
+{"text":"Other potential causes of myopathy such as chronic renal failure and other drugs were ruled out.","label":0,"label_text":"Not-Related"}
+{"text":"A previous review described data on 15 patients who experienced acute hemoglobinemia or hemoglobinuria following anti-D IGIV administration for ITP or secondary thrombocytopenia.","label":1,"label_text":"Related"}
+{"text":"The disease-modifying drugs he was taking, cyclosporin and methotrexate, were stopped, and the lymphoma resolved spontaneously without the use of chemotherapy.","label":1,"label_text":"Related"}
+{"text":"We describe a case of disseminated muscular cysticercosis followed by myositis (fever, diffuse myalgia, weakness of the lower limbs, and inflammatory reaction around dying cysticerci) induced by praziquantel therapy, an event not described previously.","label":1,"label_text":"Related"}
+{"text":"Patients treated with 5-ASA compounds who experience acute inflammatory symptoms or clinical deterioration not related to their gastrointestinal disease should be screened to rule out a lupus-like reaction.","label":0,"label_text":"Not-Related"}
+{"text":"Enoxaparin-induced generalized exanthem.","label":1,"label_text":"Related"}
+{"text":"However, this phenomenon has been largely limited to skin.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients received blood products.","label":0,"label_text":"Not-Related"}
+{"text":"Gabapentin-induced mood changes with hypomanic features in adults.","label":1,"label_text":"Related"}
+{"text":"The authors have been unable to find a similar previously published case.","label":0,"label_text":"Not-Related"}
+{"text":"Serious side effects are encountered in less than 5% of patients and this case carries one of the rarest, yet drastic, side effects of intravesical BCG.","label":0,"label_text":"Not-Related"}
+{"text":"Serotonin syndrome is an underreported complication of pharmacotherapy that has been relatively ignored in the medical literature.","label":0,"label_text":"Not-Related"}
+{"text":"The cerebrospinal fluid culture, which yielded a motile Enterococcus species, was believed to originate from the gut.","label":0,"label_text":"Not-Related"}
+{"text":"To our knowledge this is the first report that demonstrates histological abnormalities of the glomerulus associated with postoperative IFN-beta therapy for the malignant melanoma.","label":1,"label_text":"Related"}
+{"text":"The mean CAPD dialysance was only 5.27 ml\/min with less than 1% of an administered dose being recovered in the 24-hour dialysate.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was found to have a sigmoidovesical fistula and underwent sigmoidectomy and partial resection of the ileum and urinary bladder.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients with HLH developed etoposide-related secondary acute myeloid leukemia (sAML) following therapy for HLH.","label":1,"label_text":"Related"}
+{"text":"Twelve patients developed central nervous system (CNS) depression, defined as National Cancer Institute Common Toxicity Criteria (NCI-CTC) neurocortical toxicity grade 2 or higher.","label":0,"label_text":"Not-Related"}
+{"text":"A 7-year-old with congenital toxoplasmosis who took pyrimethamine and sulfadiazine for reactivated chorioretinitis developed fever, severe cutaneous involvement, swelling, abdominal pain and transaminitis, persisting weeks after withholding medicines.","label":1,"label_text":"Related"}
+{"text":"Dose related growth response to indometacin in Gitelman syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Hepatic angiosarcoma occurring after cyclophosphamide therapy: case report and review of the literature.","label":1,"label_text":"Related"}
+{"text":"Twelve patients with hematologic malignancies complicated by fungal infections were treated with liposomal amphotericin B (L-AmpB).","label":0,"label_text":"Not-Related"}
+{"text":"A 61-year-old man with early diffuse cutaneous scleroderma with myositis and progressive interstitial pneumonia developed generalized erythema with high fever 3 weeks after taking sulfamethoxazole\/trimethoprim.","label":1,"label_text":"Related"}
+{"text":"A 60-year-old white man with chronic bronchitis was noted to develop acute respiratory failure and metabolic acidosis four days after being started on methazolamide (Neptazane) for an ophthalmologic problem.","label":1,"label_text":"Related"}
+{"text":"The mortality rate is as high as 21-48% according to a recent review.","label":0,"label_text":"Not-Related"}
+{"text":"The attack was successfully treated with aggressive bronchodilator therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Hematologic evaluation disclosed pancytopenia: red blood cells 283 x 10(4)\/mm3; white blood cells 700\/mm3; and platelets 8000\/mm3.","label":0,"label_text":"Not-Related"}
+{"text":"Within 10 minutes, the occluded artery was reopened by an intracoronary (i.c.) infusion of streptokinase, resulting in the disappearance of chest pain and normalization of ST segments.","label":0,"label_text":"Not-Related"}
+{"text":"CASE SUMMARY: A 65-year-old patient chronically treated with the selective serotonin reuptake inhibitor (SSRI) citalopram developed confusion, agitation, tachycardia, tremors, myoclonic jerks and unsteady gait, consistent with serotonin syndrome, following initiation of fentanyl, and all symptoms and signs resolved following discontinuation of fentanyl.","label":1,"label_text":"Related"}
+{"text":"Many different medical and surgical remedies have been tried but none have demonstrated reproducible success.","label":0,"label_text":"Not-Related"}
+{"text":"Recently, her serum theophylline levels had increased to the toxic range (133.2 micromol\/L [24 microg\/mL]) shortly after the addition of zafirlukast (Accolate, Zeneca Pharmaceuticals, Wilmington, Del) to her regimen.","label":1,"label_text":"Related"}
+{"text":"After commencing oestrogen at physiological replacement doses, the patient experienced a marked deterioration in both the severity and frequency of angioedema attacks.","label":0,"label_text":"Not-Related"}
+{"text":"For many schizophrenic patients, treatment with conventional antipsychotic agents is not fully effective, and one approach has been to increase the administered dose.","label":0,"label_text":"Not-Related"}
+{"text":"Neuroleptic malignant syndrome (NMS) is a rare but potentially serious complication of neuroleptic drugs.","label":0,"label_text":"Not-Related"}
+{"text":"The authors present a case of t-AML that developed in a child with metastatic neuroblastoma 18 months after he received oral etoposide, given for palliation purpose.","label":1,"label_text":"Related"}
+{"text":"As termination was not an option for the family, the patient was extensively counseled and treated with oral ganciclovir.","label":0,"label_text":"Not-Related"}
+{"text":"We suggest that the specific immunosuppression used in renal transplant patients might facilitate the development of a dormant infection and in these patients the misleading presentation may delay the diagnosis.","label":0,"label_text":"Not-Related"}
+{"text":"The great majority of these patients were diagnosed with actinomycotic diseases during or after exploratory laparotomy, but rarely preoperatively.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of tardive dystonia with oral baclofen produces ambivalent and overall disappointing results.","label":0,"label_text":"Not-Related"}
+{"text":"However, the large majority of cases of leukemic transformation in ET are thought to be related to prior therapy, usually radioactive phosphorous or alkylating chemotherapy, and the development of AL in ET is extremely rare in the untreated patient.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Optic neuritis in combination with other neurological signs, simulating multiple sclerosis, should be included in the list of adverse effects of recombinant and natural interferon alpha administration.","label":1,"label_text":"Related"}
+{"text":"DISCUSSION: Central nervous system (CNS) toxicity has been described with ifosfamide, with most cases reported in the pediatric population.","label":1,"label_text":"Related"}
+{"text":"He was not rechallenged with the drug.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: This case suggests that losartan can induce late-onset angioedema in patients with normal renal function and that the reaction can recur after initial resolution of the symptoms.","label":1,"label_text":"Related"}
+{"text":"High-strength pancreatic enzymes have recently been implicated as a cause of colonic strictures in children with cystic fibrosis (CF).","label":0,"label_text":"Not-Related"}
+{"text":"A MEDLINE search from 1966 to December 2000 revealed no reports of toxic epidermal necrolysis, erythema multiforme, or Stevens-Johnson syndrome due to ofloxacin therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Corneal scrapings were taken and the flap excised, and submitted for histopathologic examination.","label":0,"label_text":"Not-Related"}
+{"text":"We hypothesize that caffeine toxicity injured the muscle cells, which were fragile due to the potassium depletion induced by the coexisting hyponatremia, to result in unusually severe rhabdomyolysis.","label":1,"label_text":"Related"}
+{"text":"In one patient the vasculitis resolved after termination of the ciprofloxacin therapy; in the other patient the ciprofloxacin-induced hemorrhagic vasculitis was superimposed on a severe forefoot infection, leading to progressive gangrene and a below-knee amputation.","label":1,"label_text":"Related"}
+{"text":"Our report suggests the efficacy of PES as ACAD treatment of the unprotected LMCA.","label":0,"label_text":"Not-Related"}
+{"text":"A karyotype showed 1) the involvement of 12p, which should be related to the basophilia and\/or to previous drug exposure, and 2) the unexpected presence of three different dicentric chromosomes.","label":0,"label_text":"Not-Related"}
+{"text":"Imipenem was given for 2 days, resulting in a total of 18 days of beta-lactam treatment, at which time he developed significant leukopenia (white blood cell [WBC] count 0.9 x 10(3)\/microL).","label":0,"label_text":"Not-Related"}
+{"text":"Seizures and extrapyramidal symptoms in a patient with Tourette's syndrome, Asperger's syndrome, and multiple sclerosis treated with interferon beta-1a and clomipramine.","label":1,"label_text":"Related"}
+{"text":"Eosinophilic cystitis is a rare and poorly understood disorder.","label":0,"label_text":"Not-Related"}
+{"text":"Multicentric canine lymphoma in a 12-year-old keeshond: chemotherapy options.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: The new quinolone derivatives (levofloxacin, sparfloxacin, grepafloxacin, trovafloxacin, gatifloxacin and moxifloxacin), also called gyrase inhibitors, are known for their potential to cause central nervous system-related adverse effects, including headache, dizziness and insomnia.","label":1,"label_text":"Related"}
+{"text":"Captopril-induced bone marrow suppression in two cardiac patients with trisomy 21.","label":1,"label_text":"Related"}
+{"text":"We introduce a case of a sixty years old woman with several previous episodes of rhinitis, conjunctivitis and perspiration immediately after the administration of salmon calcitonin with nasal spray or intramuscular administration (Calsynar).","label":1,"label_text":"Related"}
+{"text":"METHODS: Prospective, interventional, single case report.","label":0,"label_text":"Not-Related"}
+{"text":"The dermatomes below the Th9 lost all somatic sensation on the left side after the nerve blocks, but the patient was not completely relieved from the pain.","label":0,"label_text":"Not-Related"}
+{"text":"Electron microscopic analysis also revealed a minor population of small adipocytes, suggesting active differentiation or proliferation.","label":0,"label_text":"Not-Related"}
+{"text":"All-trans-retinoic acid (ATRA) has been proved to be an effective treatment for acute promyelocytic leukemia (APL), inducing remission in more than 90% of cases.","label":0,"label_text":"Not-Related"}
+{"text":"Therefore, careful handling of the conjunctiva with a nontoothed forceps is essential.","label":0,"label_text":"Not-Related"}
+{"text":"Two months after thymectomy she presented with progressive cognitive decline, asymmetric quadriparesis and ataxia.","label":0,"label_text":"Not-Related"}
+{"text":"The neuropathology of organ transplantation: comparison and contrast in 500 patients.","label":0,"label_text":"Not-Related"}
+{"text":"The ECG showed a coved ST-segment elevation in the right precordial leads V1-V3, a pattern mimicking BS.","label":0,"label_text":"Not-Related"}
+{"text":"Conversely, diffuse interstitial pulmonary fibrosis should be considered in the differential diagnosis of patients receiving methotrexate who develop bilateral pulmonary infiltrates seen on chest roentgenograms.","label":1,"label_text":"Related"}
+{"text":"From these, three patients with myopathy were found for a total of 303 patient-years of therapy, for an incidence of 1 in 100 patient-years (95%, confidence interval 0.2-3).","label":0,"label_text":"Not-Related"}
+{"text":"Diagnostic testing could not be completed due to lack of clinical response to dexamethasone.","label":0,"label_text":"Not-Related"}
+{"text":"During hospitalization, he was treated with regular insulin and 300 mg\/day of acarbose.","label":0,"label_text":"Not-Related"}
+{"text":"The process healed after surgical treatment and chemotherapy for 1 year.","label":0,"label_text":"Not-Related"}
+{"text":"Minoxidil, hypercoagulability and thromboembolic disease of the lung.","label":0,"label_text":"Not-Related"}
+{"text":"The site of thrombosis and the chronological relationship with the IIR implicates a hypersensitivity to infliximab in the causation of the venous thrombosis in this case.","label":1,"label_text":"Related"}
+{"text":"The patient was diagnosed with bilateral acute angle glaucoma, and despite aggressive medical and surgical intervention, the patient did not have her vision restored to normal.","label":0,"label_text":"Not-Related"}
+{"text":"Rhodococcus equi pulmonary-central nervous system syndrome: brain abscess in a patient on high-dose steroids--a case report and review of the literature.","label":0,"label_text":"Not-Related"}
+{"text":"A total of 1.5% (n = 41) and 2.0% (n = 52) of patients were receiving fluoxetine or tricyclics (amitriptyline or nortriptyline, n = 31; imipramine or desipramine, n = 16; protriptyline or trimipramine, n = 5).","label":0,"label_text":"Not-Related"}
+{"text":"Heparin-dependent antibodies and thrombosis without heparin-induced thrombocytopenia.","label":1,"label_text":"Related"}
+{"text":"The Naranjo probability scale suggests a highly probable relationship between AIN and pantoprazole therapy in this patient.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND AND OBJECTIVES: The occurrence of concomitant intracranial pathology in a patient with postdural puncture headache (PDPH) is rare.","label":0,"label_text":"Not-Related"}
+{"text":"To determine the clinical significance of this organism, we reviewed the records of all patients whose blood cultures were positive for E. avium who were seen at our institution from 1986 through 1991 and identified nine cases of bacteremia due to E. avium.","label":0,"label_text":"Not-Related"}
+{"text":"Keratitis in methamphetamine abusers.","label":1,"label_text":"Related"}
+{"text":"Airway obstruction complicating esophageal stent placement in two post-pneumonectomy patients.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of an 11-year-old female treated for mediastinal T-cell lymphoma who presented renal failure following the second cycle of high-dose methotrexate (HDMTX).","label":1,"label_text":"Related"}
+{"text":"During the follow up period we did not observe residue or recurrence of the ptosis.","label":0,"label_text":"Not-Related"}
+{"text":"Data of drug monitoring demonstrated rapid metabolism and\/or distribution of KW-2149 with a short half-life and the emergence of the cytotoxic metabolites M-16 and M-18.","label":0,"label_text":"Not-Related"}
+{"text":"Drug eruption associated with sulfonamide treatment of vertebral osteomyelitis in a dog.","label":0,"label_text":"Not-Related"}
+{"text":"It seems that the anti-cancer agent evoked inflammation at the visceral pleura and the subject inhaled massive air flow into the systemic circulation.","label":0,"label_text":"Not-Related"}
+{"text":"A 27-year-old man who had a history of bronchial asthma, eosinophilic enteritis, and eosinophilic pneumonia presented with fever, skin eruptions, cervical lymphadenopathy, hepatosplenomegaly, atypical lymphocytosis, and eosinophilia two weeks after receiving trimethoprim (TMP)-sulfamethoxazole (SMX) treatment.","label":1,"label_text":"Related"}
+{"text":"Capecitabine (CAP) is a pro-drug of 5-FU and peripheral neuropathy associated with CAP has not been reported.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: A 79-year-old woman was hospitalized in our unit with posterior thoracic pain and urinary retention of 72 hours duration.","label":0,"label_text":"Not-Related"}
+{"text":"Strychnine poisoning in an adolescent.","label":0,"label_text":"Not-Related"}
+{"text":"In those patients who found the commercially available cream uncomfortable, a 1% clotrimazole suspension formulated in artificial tears was used and found to be well tolerated.","label":0,"label_text":"Not-Related"}
+{"text":"Adverse events with anti-epidermal growth factor receptor therapy mainly involve the skin.","label":0,"label_text":"Not-Related"}
+{"text":"Initial treatment with itraconazole resulted in exacerbation of clinical signs.","label":0,"label_text":"Not-Related"}
+{"text":"Intravenous bolus administration of magnesium (Mg) sulfate, followed by intramuscular Mg repletion, abolished the digitalis-toxic arrhythmia.","label":0,"label_text":"Not-Related"}
+{"text":"The hypertrophic adipocytes were twice as large as those from normal subcutaneous areas and contained numerous small lipid droplets.","label":0,"label_text":"Not-Related"}
+{"text":"Between 1993 and 1997, 52 patients (age 16-77 years) with solid tumours were treated with ifosfamide in dosages ranging from 3 to 5 g m(-2) q3w when given in combination schedules and up to 12 g m(-2) q4w when given as a single agent.","label":0,"label_text":"Not-Related"}
+{"text":"In this paper, the authors present a case in which the current American Society for Regional Anesthesia and Pain Medicine guidelines were strictly followed with respect to withholding and reintroducing warfarin and enoxaparin after an epidural steroid injection, but the patient nevertheless developed a spinal epidural hematoma requiring emergency surgical evacuation.","label":0,"label_text":"Not-Related"}
+{"text":"Heparin-associated thrombocytopenia and thrombosis is a severe complication of systemic heparin therapy.","label":1,"label_text":"Related"}
+{"text":"In addition to severe vegetative anticholinergic symptoms, the clinical picture is often dominated by a toxic psychosis with hallucinations, disturbances of orientation, and psychomotoric agitation, aggression, or anxiety.","label":0,"label_text":"Not-Related"}
+{"text":"Asthmatic medications can place the patient at risk of dental erosion by reducing salivary protection against extrinsic or intrinsic acids.","label":0,"label_text":"Not-Related"}
+{"text":"Only a few reports of overt jaundice are associated with streptokinase.","label":1,"label_text":"Related"}
+{"text":"The infants in the other two reported cases also died, which suggests that TEN in early infancy has an extremely poor prognosis.","label":0,"label_text":"Not-Related"}
+{"text":"Although the cardiotoxicity of 5-FU is well documented, there is little published data about cardiovascular adverse effects of Capecitabine.","label":0,"label_text":"Not-Related"}
+{"text":"A 7-year-old boy developed a severe unilateral grand mal seizure at the age of 5 years (phenobarbitone therapy); 1.5 years later valproate (2-propylpentanoic acid, VPA) was added to the therapy.","label":1,"label_text":"Related"}
+{"text":"Recognition of this acute drug-induced state can lead to appropriate short-term pharmacotherapy and can prevent misdiagnosis of a major affective disorder or schizophrenia.","label":0,"label_text":"Not-Related"}
+{"text":"In this uncontrolled series of patients with recalcitrant palmoplantar pompholyx, methotrexate was an effective treatment and acted as a steroid-sparing agent.","label":0,"label_text":"Not-Related"}
+{"text":"To the best of our knowledge, this is the first case of lithium-associated CDI and NDI presenting concurrently.","label":1,"label_text":"Related"}
+{"text":"Treatment of the underlying cause and supportive care constitute the basic principles of management of disseminated intravascular coagulation.","label":0,"label_text":"Not-Related"}
+{"text":"These disorders may be the basic clinical manifestation of cancer or may result from vigorous cancer treatment.","label":0,"label_text":"Not-Related"}
+{"text":"One patient had an implant of serous papillary carcinoma of low malignant potential at the trocar sites after laparoscopic oophorectomy.","label":0,"label_text":"Not-Related"}
+{"text":"Hypersensitivity reaction to sulindac (Clinoril).","label":0,"label_text":"Not-Related"}
+{"text":"We encountered a child who was intolerant to multiple commercially available preparations of pancreatic enzymes and, hence, desensitization was attempted, with success.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients had a history of schizophrenia.","label":0,"label_text":"Not-Related"}
+{"text":"The multiple comedones and ruptured epidermoid cysts are newly reported adverse effects of imiquimod therapy.","label":1,"label_text":"Related"}
+{"text":"Its disadvantage is that therapy may be necessary for several months.","label":0,"label_text":"Not-Related"}
+{"text":"Exfoliative dermatitis secondary to tobramycin sulfate.","label":1,"label_text":"Related"}
+{"text":"Twelve hours after admission, \"diabetic ketoacidosis\" was diagnosed on the basis of elevated glycaemia, glycosuria, ketonuria and a low bicarbonate blood level, which led to treatment with fluids and regular insulin infusion.","label":0,"label_text":"Not-Related"}
+{"text":"In the highly active antiretroviral therapy era, an increasingly large number of HIV-infected patients are developing non- AIDS-defining cancers (NADCs).","label":0,"label_text":"Not-Related"}
+{"text":"His symptoms of amnesia resolved approximately 6-7 hours after discontinuing the propafenone therapy.","label":0,"label_text":"Not-Related"}
+{"text":"These agents have potent cytotoxic and immunomodulatory effects and are useful in the treatment of a variety of conditions, including inflammatory bowel disease.","label":0,"label_text":"Not-Related"}
+{"text":"No other endogenous or exogenous cause for the gynecomastia could be found except for the theophylline.","label":1,"label_text":"Related"}
+{"text":"The obligatory use of fluoroscopy for placement of epidural steroids is controversial.","label":0,"label_text":"Not-Related"}
+{"text":"Clonazepam in the treatment of prepubertal children with panic-like symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"We present three cases from the Provincial Toxicology Center of British Columbia, Canada in which suicidal overdose deaths were associated with quetiapine.","label":1,"label_text":"Related"}
+{"text":"During her third cycle, she again received cisplatin 100 mg\/m2 over 30 minutes and developed palmar pruritus, urticaria, and edema.","label":1,"label_text":"Related"}
+{"text":"We recommend that fluorinated glucocorticosteroids should not be used on the face of infants and children.","label":0,"label_text":"Not-Related"}
+{"text":"The growing number of United States Food and Drug Administration-approved antidiabetic agents provides a wide range of therapeutic options, both as monotherapy and combination therapy, for treating hyperglycemia in patients with type 2 diabetes.","label":0,"label_text":"Not-Related"}
+{"text":"We discuss a patient who developed severe renal tubular dysfunction secondary to short-term therapy with Amikacin, resulting in refractory hypokalemia, hypocalcemia, hypomagnesemia, metabolic alkalosis, and polyuria.","label":1,"label_text":"Related"}
+{"text":"This case raises the possibility that chronic exposure to cyanoacrylates, the adhesive agents in industrial strength glue, may be associated with the development of acute lymphoblastic leukemia in humans.","label":0,"label_text":"Not-Related"}
+{"text":"SETTING: Hospital.","label":0,"label_text":"Not-Related"}
+{"text":"A 58-year-old woman with rheumatoid arthritis (RA) developed fever, skin eruptions, leukocytopenia, and thrombocytopenia, 3 weeks after treatment with sulfasalazine.","label":1,"label_text":"Related"}
+{"text":"The association of NEH and the use of cytotoxic agents for SLE or other autoimmune diseases has not been reported previously.","label":0,"label_text":"Not-Related"}
+{"text":"Whether this represents a cause-effect association or a chance occurrence is unknown.","label":0,"label_text":"Not-Related"}
+{"text":"Because there is no shortage of intravenous thiamine, it should be administered with TPN even if MVI is not available.","label":0,"label_text":"Not-Related"}
+{"text":"A 66-year-old Japanese woman with severe scleroderma developed anemia and thrombocytopenia due to D-penicillamine (D-Pen) treatment, although the leukopenia was not markedly severe.","label":1,"label_text":"Related"}
+{"text":"The other patient developed transient intraoperative hypertension immediately after inadvertent submucosal injection of concentrated epinephrine.","label":1,"label_text":"Related"}
+{"text":"Desipramine-associated SIADH in an elderly woman: case report.","label":1,"label_text":"Related"}
+{"text":"Two reports of spindle coma are noted with alcohol and imipramine.","label":1,"label_text":"Related"}
+{"text":"Cefuroxime-induced immune hemolysis.","label":1,"label_text":"Related"}
+{"text":"To our knowledge, hyperpigmentation of the skin--and especially of the tongue--has not been reported so far.","label":0,"label_text":"Not-Related"}
+{"text":"We report 4 cases in patients with Cystic Fibrosis (CF) associated with totally implantable venous access device system (TIVADS).","label":0,"label_text":"Not-Related"}
+{"text":"Malignancy, infection and cardiomyopathy were excluded as causes of dyspnoea.","label":0,"label_text":"Not-Related"}
+{"text":"John's Wort by adolescents with a psychiatric disorder.","label":0,"label_text":"Not-Related"}
+{"text":"For the first time, an analytical method for the determination of carbachol in plasma and urine has been developed.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To study therapy with indapamide impairing carbohydrate metabolism in essential hypertension patients and achieve earlier prevention, diagnoses and treatment of diabetes induced by indapamide.","label":1,"label_text":"Related"}
+{"text":"The buried bumper syndrome is a rare and late complication of percutaneous endoscopic gastrostomy tube placement.","label":0,"label_text":"Not-Related"}
+{"text":"Captopril-induced pulmonary infiltrates with eosinophilia in an infant with congenital heart disease.","label":1,"label_text":"Related"}
+{"text":"Hemodiafiltration with a high-flux polysulfone membrane is a novel and safe treatment modality for vancomycin overdose in pediatric patients.","label":0,"label_text":"Not-Related"}
+{"text":"We report a 38-year-old woman with a history of smoking and pre-eclampsia in her previous pregnancy, who suffered a non-Q infarction at 18 weeks of gestation.","label":0,"label_text":"Not-Related"}
+{"text":"Favorable outcome of de novo hepatitis B infection after liver transplantation with lamivudine and adefovir therapy.","label":1,"label_text":"Related"}
+{"text":"Given the limited experience with this agent in treating behavioural disorders associated with DLB, further studies are warranted.","label":0,"label_text":"Not-Related"}
+{"text":"The case is reported of eosinophilia-myalgia syndrome and polyneuropathy associated with myeloperoxidase specific antineutrophil cytoplasmic antibody.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case histories of identical twin brothers who developed concordant acute lymphoblastic leukemia at the age of 4 years and who later developed leukoencephalopathy and hydrocephalus related to central nervous system prophylaxis by, in the first case intrathecally administered methotrexate and, in the second by intrathecally administered methotrexate and cranial irradiation.","label":1,"label_text":"Related"}
+{"text":"Electrical proarrhythmia with procainamide: a new ICD-drug interaction.","label":1,"label_text":"Related"}
+{"text":"We suggest that this form of treatment is of value for cholangiocarcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: Prolonged unsupervised use of glucocorticoid ocular drops may result in Cushing's syndrome and its numerous associated complications.","label":0,"label_text":"Not-Related"}
+{"text":"This responded well to steroids and cyclophosphamide.","label":0,"label_text":"Not-Related"}
+{"text":"A 44-year-old woman is described in whom amiodarone, disopyramide, and quinidine, administered alone separately, induced atypical ventricular tachycardia (AVT, torsade de pointes).","label":1,"label_text":"Related"}
+{"text":"No other site of invasive aspergillosis was evident.","label":0,"label_text":"Not-Related"}
+{"text":"Coadministration of antidepressant agents such as nefazodone, or any other drug that inhibits the CYP3A4 isoenzyme subfamily, should be anticipated to interfere with tacrolimus metabolism.","label":1,"label_text":"Related"}
+{"text":"Osteomyelitis of the fibula due to septic embolism: a rare complication of a graft enteric erosion.","label":0,"label_text":"Not-Related"}
+{"text":"PATIENT AND HISTORY: A 58-year-old man with GIST metastatic to the right lobe of the liver, treated with tyrosine kinase inhibitors, underwent a right hepatectomy requiring multiple transfusions.","label":0,"label_text":"Not-Related"}
+{"text":"Cardiac ischemia is a well-known and serious complication during surgery.","label":0,"label_text":"Not-Related"}
+{"text":"One patient had a lower average heart rate and two patients had lower average mean blood pressure values during propranolol treatment, none of which was clinically significant.","label":1,"label_text":"Related"}
+{"text":"Collected cases are reviewed from the literature, and the common features are summarized.","label":0,"label_text":"Not-Related"}
+{"text":"Classification included dry (7%), mild (48%), moderate (39%), and severe (6%).","label":0,"label_text":"Not-Related"}
+{"text":"The pharmacist conducted a thorough medication review, which revealed the use of several herbal products, including St.","label":0,"label_text":"Not-Related"}
+{"text":"Minor reactions to the drug are very common, but severe idiosyncratic reactions are rare considering the large number of patients taking this drug worldwide.","label":0,"label_text":"Not-Related"}
+{"text":"Early phase-II semi double-blind study of the new alkaline propanolamine derivative enciprazine (short communication).","label":0,"label_text":"Not-Related"}
+{"text":"Thirteen patients with squamous cell carcinoma (SCC) and 3 patients with non-SCC who had recurrent\/metastatic disease received S-1 monotherapy as outpatients.","label":0,"label_text":"Not-Related"}
+{"text":"Isotretinoin teratogenicity.","label":1,"label_text":"Related"}
+{"text":"Laryngeal necrosis after combined chemotherapy and radiation therapy.","label":0,"label_text":"Not-Related"}
+{"text":"However, the composition of the mixture had been modified by the manufacturer in the past 5 months, with addition of boldo leaf extracts.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of atenolol overdose in a patient with renal failure using serial hemodialysis and hemoperfusion and associated echocardiographic findings.","label":0,"label_text":"Not-Related"}
+{"text":"The authors documented maternal intake of diazepam in the range of 40-60 mg\/day for a duration of 4-27 weeks prior to delivery.","label":0,"label_text":"Not-Related"}
+{"text":"INTERVENTION: Intravenous pyridoxine was used in five episodes.","label":0,"label_text":"Not-Related"}
+{"text":"A 55- year-old man had been followed for chronic hepatitis B infection for 10 years at another institution.","label":0,"label_text":"Not-Related"}
+{"text":"DISCUSSION: Both cases met Stembach's criteria for serotonin syndrome and had serious extrapyramidal movement disorders.","label":0,"label_text":"Not-Related"}
+{"text":"An amiodarone optic neuropathy has been described.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND: Controversy exists regarding the timing of thrombolytic administration and rupture rate.","label":0,"label_text":"Not-Related"}
+{"text":"Camptocormia improved within a week after the reduction of the plasma valproate level to about 300 mumol\/l.","label":0,"label_text":"Not-Related"}
+{"text":"Patients received infliximab infusions at a dose of 5 mg\/kg, initially at weeks 0, 2 and 6 and subsequently at 8 weeks intervals in combination with an immunomodulator drug.","label":0,"label_text":"Not-Related"}
+{"text":"Implications for professionals who care for lactating women are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Methotrexate (MTX) may induce liver damage, which in some psoriatics will lead to fibrosis or cirrhosis.","label":1,"label_text":"Related"}
+{"text":"The ulcer did not respond to antibiotic treatment and healed shortly after withholding ATRA.","label":1,"label_text":"Related"}
+{"text":"Presentation of 2 cases and review of the literature.","label":0,"label_text":"Not-Related"}
+{"text":"Methotrexate-induced diffuse interstitial pulmonary fibrosis.","label":1,"label_text":"Related"}
+{"text":"The mechanism behind the development of the cutaneous lesions is unclear, and could have either a casual clinical association or be related to the study drug.","label":0,"label_text":"Not-Related"}
+{"text":"CMV reactivation is frequently observed in acute flares of ulcerative colitis (UC), particularly those which do not respond to intravenous steroids.","label":0,"label_text":"Not-Related"}
+{"text":"Danazol at 400 mg per day was therefore again administered.","label":0,"label_text":"Not-Related"}
+{"text":"An asymptomatic HIV-infected woman experienced right-sided renal colicky pain during treatment with indinavir.","label":1,"label_text":"Related"}
+{"text":"We present four cases in which the use of heparin was associated with hyperkalemia and discuss the pathophysiology.","label":1,"label_text":"Related"}
+{"text":"Fluoxetine suppresses human cataplexy: a pilot study.","label":0,"label_text":"Not-Related"}
+{"text":"In most of these studies, the effect of acarbose (on reactive hypoglycemia) was evaluated over several hours postprandially or after oral glucose load.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a case of advanced ovarian carcinoma who developed difficulty walking because of marked pain in the lower extremities and loss of proprioception 25 days after treatment with weekly taxol (80 mg\/m(2)x3).","label":1,"label_text":"Related"}
+{"text":"We present a case in which dipyridamole induced high-grade atrioventricular (AV) block that responded promptly to intravenous aminophylline but not to atropine.","label":1,"label_text":"Related"}
+{"text":"The authors report a world class runner who sustained a rupture requiring surgical intervention.","label":0,"label_text":"Not-Related"}
+{"text":"Warfarin was discontinued and restarted at 7.5 mg\/wk.","label":0,"label_text":"Not-Related"}
+{"text":"Sequencing of the mitochondrial polymerase gamma gene (POLG1) revealed four heterozygous substitutions, two of which have been identified in cases of Alpers-Huttenlocher disease.","label":0,"label_text":"Not-Related"}
+{"text":"Transient left homonymous hemianopsia and encephalopathy following treatment of testicular carcinoma with cisplatinum, vinblastine, and bleomycin.","label":1,"label_text":"Related"}
+{"text":"The authors describe their use of midodrine in a dialysis patient for the longest period of time reported up to now, documented by a pharmacokinetic study, confirming long-term both clinical efficacy and safety of the drug.","label":0,"label_text":"Not-Related"}
+{"text":"We present a case of stroke after PPA ingestion that occurred 4 months after the recall in an 8-year-old boy on chronic peritoneal dialysis.","label":1,"label_text":"Related"}
+{"text":"Persistent triamcinolone acetonide particles on the posterior lens capsule after intravitreal injection.","label":0,"label_text":"Not-Related"}
+{"text":"Its use is however not without adverse effect particularly bone marrow aplasia leading to varying degrees of cytopenias predominantly anaemia.","label":0,"label_text":"Not-Related"}
+{"text":"However, 3 months after withdrawal of treatment, the patient still showed clinical and laboratory symptoms of systemic lupus erythematosus.","label":0,"label_text":"Not-Related"}
+{"text":"During the 12th week of treatment she showed transient thyrotoxicosis.","label":0,"label_text":"Not-Related"}
+{"text":"Methotrexate-induced liver cirrhosis.","label":1,"label_text":"Related"}
+{"text":"It has been suggested that PPE caused by cytarabine does not recur with subsequent cytarabine re-challenge.","label":1,"label_text":"Related"}
+{"text":"Arthroscopic posterior cruciate ligament reconstruction may carry certain risks of complications, including injury to the neurovascular structures in the popliteal region.","label":0,"label_text":"Not-Related"}
+{"text":"The occurrence of symptoms that could be ascribed to an acute coronary syndrome should always be taken seriously during the first rituximab infusion and investigated aggressively.","label":1,"label_text":"Related"}
+{"text":"Among 12 thyrotoxic patients, a patient with arrhythmogenic right ventricular dysplasia, who had been taking amiodarone for 4 years, developed thyrotoxicosis with subacute onset, accompanied by transiently positive thyrotropin (TSH) receptor antibody (TRAb), or thyrotropin-binding inhibiting immunoglobulin (TBII).","label":1,"label_text":"Related"}
+{"text":"We recommend routine follow up by ECG of patients over the age of 50 treated with carbamazepine.","label":0,"label_text":"Not-Related"}
+{"text":"They cause impairment of hepatic glucose output and delay in intestinal absorption of carbohydrates.","label":0,"label_text":"Not-Related"}
+{"text":"Modern ergotism.","label":0,"label_text":"Not-Related"}
+{"text":"While in remission the patient developed acute leukemia.","label":0,"label_text":"Not-Related"}
+{"text":"The granular layer was preserved and, in some areas, hypergranulosis was found (Fig.","label":0,"label_text":"Not-Related"}
+{"text":"However, dermatologists should be cautious about a photosensitivity reaction induced by mequitazine or other phenothiazine-derivative drugs.","label":1,"label_text":"Related"}
+{"text":"Diarrhoea, T-CD4+ lymphopenia and bilateral patchy pulmonary infiltrates developed in a male 60 yrs of age, who was treated with oxaliplatinum and 5-fluorouracil for unresectable rectum carcinoma.","label":1,"label_text":"Related"}
+{"text":"All patients were given pharmacologic doses of vitamin D, had reduced baseline levels of renal function, and became hypercalcemic with acute renal failure.","label":0,"label_text":"Not-Related"}
+{"text":"Withdrawal of lansoprazole lead to prompt and sustained relief.","label":0,"label_text":"Not-Related"}
+{"text":"While mortality from trauma increases, there has been a decline in mortality from cardiovascular and cerebrovascular diseases which parallels advances in antithrombotic and anticoagulation therapy.","label":0,"label_text":"Not-Related"}
+{"text":"A 66-year-old woman was diagnosed as having pulmonary adenocarcinoma with malignant pleural effusion following investigations for cough and dyspnea.","label":0,"label_text":"Not-Related"}
+{"text":"Carotid artery dissection in ergotamine abuse.","label":0,"label_text":"Not-Related"}
+{"text":"Lithium therapy was discontinued because of poor compliance to the medication and intolerable polyuria.","label":1,"label_text":"Related"}
+{"text":"Formation of these plugs was probably due to extensive tumor necrosis at the level of the walls of the major uterine veins, which resulted in an open exchange of tumor plugs to the vascular spaces; decrease in tumor tissue coherence secondary to chemotherapy may have further contributed to the formation of tumor emboli.","label":0,"label_text":"Not-Related"}
+{"text":"Minor trauma to the tissue, such as tooth extraction, can trigger life-threatening laryngeal edema.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients developed posterior subcapsular cataract.","label":0,"label_text":"Not-Related"}
+{"text":"Skin necrosis secondary to low-molecular weight heparin in a patient with antiphospholipid antibody syndrome.","label":1,"label_text":"Related"}
+{"text":"A 53-year-old postmenopausal woman, who had a family history of cryptogenic liver cirrhosis, was diagnosed with osteoporosis, and started on the selective estrogen receptor modulator (SERM) raloxifene 60 mg\/day orally.","label":0,"label_text":"Not-Related"}
+{"text":"Muscle biopsy revealed variation in muscle fiber size and few vacuolated fibers which were features of colchicine-induced myopathy.","label":1,"label_text":"Related"}
+{"text":"The response to pain-related treatments and to preventive drugs was poor in the symptomatic as well as in the primary cases.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: Retrospective consecutive noncomparative case series.","label":0,"label_text":"Not-Related"}
+{"text":"It is suggested that many of the reported side-effects of o,p'-DDD may be due to hypoadrenalism and may be controlled by greatly increasing the steroid replacement dose.","label":0,"label_text":"Not-Related"}
+{"text":"With careful parental support, his sodium levels remained stable for many years on a fixed dose of DDAVP and a supervised fluid intake of 2.5 l\/day.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Prompt and appropriate identification and intervention are essential for successful management of SS and NMS.","label":0,"label_text":"Not-Related"}
+{"text":"In this report, one patient who developed gangrene after bleomycin and vincristine\/vinblastine chemotherapy for AIDS-related Kaposi's sarcoma and another HIV-infected patient who exhibited symptoms of severe Raynaud's phenomenon related to the same regimen are presented.","label":1,"label_text":"Related"}
+{"text":"Finally, after 9 years of infection, the diagnosis of seropositive RA was made in this HLA-DR1 positive patient.","label":0,"label_text":"Not-Related"}
+{"text":"Severe corneal toxicity after topical fluoroquinolone therapy: report of two cases.","label":1,"label_text":"Related"}
+{"text":"Three of the five patients had undergone endoscopy.","label":0,"label_text":"Not-Related"}
+{"text":"The mean hematocrit level in the study population was 19.8% before therapy and 31.5% after therapy.","label":0,"label_text":"Not-Related"}
+{"text":"The diagnosis of encephalomyelitis was made on day 3 after methotrexate administration, and by day 6 mechanical ventilation was begun secondary to ascending paralysis.","label":0,"label_text":"Not-Related"}
+{"text":"The effect of fluoxetine, a potent and specific serotonin reuptake inhibitor, on NREM eye movements is postulated to derive from potentiation of serotonergic neurons that inhibit brainstem \"omnipause neurons\", which, in turn, inhibit saccadic eye movements, thus resulting in disinhibited release of saccades.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: De novo inflammatory bowel disease should be considered in patients in whom chronic diarrhea develops after an orthotopic liver transplant.","label":0,"label_text":"Not-Related"}
+{"text":"These data further suggest that degradation by the ubiquitin-proteosome-mediated system plays a role in the elimination of the DPD protein.","label":0,"label_text":"Not-Related"}
+{"text":"Fever was a constant finding, frequently accompanied by signs of central nervous system dysfunction.","label":0,"label_text":"Not-Related"}
+{"text":"Fulminant malignant hyperthermia associated with ketoacidotic diabetic coma.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: An indium (111) DTPA flow study is a non-invasive, safe and patient friendly diagnostic method which can be of great help in the evaluation of pump- or catheter-related complications and does not need to interfere with the delivery of CITB.","label":0,"label_text":"Not-Related"}
+{"text":"Video game epilepsy is considered to be its variant or a pattern sensitive epilepsy.","label":0,"label_text":"Not-Related"}
+{"text":"A 35-year-old man with refractory low grade diffuse centroblastic centrocytic non-Hodgkin's lymphoma was treated accidentally with an overdose of multiple chemotherapeutic agents.","label":0,"label_text":"Not-Related"}
+{"text":"Renal arterial thrombosis, usually in association with aortic thrombosis, has been reported as a result of prolonged neonatal umbilical artery catheterization.","label":0,"label_text":"Not-Related"}
+{"text":"The management of the patient's withdrawal symptoms is described.","label":0,"label_text":"Not-Related"}
+{"text":"Risperidone appears effective in controlling agitation in patients with dementia and has a relatively benign adverse-effect profile, but more clinical trials are needed to elucidate its role for this indication.","label":0,"label_text":"Not-Related"}
+{"text":"A marked decrease in uterine size occurred within 12 months of insertion accompanied by resolution of the menorrhagia and dysmenorrhea.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Post-allogeneic haematopoietic stem cell transplantation (HSCT) membranous nephropathy (MN), a rare complication of HSCT, remains an ill-defined entity.","label":0,"label_text":"Not-Related"}
+{"text":"Four case reports presenting new acquisitions on the association between breast and endometrial carcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"Conservative therapy with oxygen and metronidazole improved the PI symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"Corticosteroid administration was ineffective, whereas a prompt response to cyclosporine was observed.","label":0,"label_text":"Not-Related"}
+{"text":"The present study describes a patient who had unusual weight fluctuation under corticosteroid and psychotropic treatment such as mianserin and aripiprazole.","label":1,"label_text":"Related"}
+{"text":"A middle-aged architect, suffering from familial, idiopathic, levodopa-responsive restless legs syndrome (RLS) progressively abused levodopa for 10 years, to the point of taking 20 tablets\/day (4000 mg\/day) for 6 months.","label":0,"label_text":"Not-Related"}
+{"text":"One week after suspension, ocular pressure of the patients was 17 and 18 mmHg, respectively.","label":0,"label_text":"Not-Related"}
+{"text":"Triptans are specific agonists of the serotonergic 5-HT(1B\/1D) receptors that have increasingly been used in the treatment of migraine and cluster headaches.","label":0,"label_text":"Not-Related"}
+{"text":"After failure to respond to antibiotics, aminosalicylates and immunomodulators such as azathioprine and 6-mercaptopurine (6-MP), all patients were treated with infliximab.","label":0,"label_text":"Not-Related"}
+{"text":"It is estimated that 3-10% of children with acute lymphoblastic leukemia (ALL) experience acute, transient neurotoxicity during induction chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Management of hypophosphatemia induced by high-flux hemodiafiltration for the treatment of vancomycin toxicity: intravenous phosphorus therapy versus use of a phosphorus-enriched dialysate.","label":1,"label_text":"Related"}
+{"text":"Clozapine-induced tardive dyskinesia in schizophrenic patients taking clozapine as a first-line antipsychotic drug.","label":1,"label_text":"Related"}
+{"text":"A follow-up cerebral angiogram demonstrated a small AVM arising off a branch of the pericallosal artery and a small arteriovenous fistula arising off the costal marginal branch.","label":0,"label_text":"Not-Related"}
+{"text":"Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is reported in up to 18.6% of patients treated with intravenous bisphosphonates and can result in significant morbidity.","label":1,"label_text":"Related"}
+{"text":"Only a few cases of candidal abscess of the pancreas have been reported, none of them having occurred after an ERCP.","label":0,"label_text":"Not-Related"}
+{"text":"Upon subsequent reduction and discontinuation of phenobarbital, however, chlorpromazine was able to be reduced with no increase in target behaviors.","label":0,"label_text":"Not-Related"}
+{"text":"Two other members of the family who were on treatment for tuberculosis but had not taken isoniazid on the day of the episode were unaffected by the same meal.","label":0,"label_text":"Not-Related"}
+{"text":"High-dose methotrexate-associated acute renal failure may be an avoidable complication.","label":1,"label_text":"Related"}
+{"text":"The prepuce as a donor site for reconstruction of an extravasation injury to the foot in a newborn.","label":0,"label_text":"Not-Related"}
+{"text":"Patients with vitamin B12 deficiency are exceedingly sensitive to neurologic deterioration following nitrous oxide anesthesia.","label":1,"label_text":"Related"}
+{"text":"Successful intervention is seldom reported.","label":0,"label_text":"Not-Related"}
+{"text":"It is important to keep a high index of suspicion with regard to DIAN since it is usually rapidly reversible.","label":0,"label_text":"Not-Related"}
+{"text":"ADH hypersecretion in relation to plasma osmolality was reversed by mizoribin withdrawal, suggesting that bredinin might adversely induce SIADH.","label":1,"label_text":"Related"}
+{"text":"Patients in this age group receiving antimanic maintenance treatment should keep lithium serum levels as low as possible.","label":0,"label_text":"Not-Related"}
+{"text":"Eventually, his bowel was reduced to 40 cm of small intestine, including 5 cm of terminal ileum.","label":0,"label_text":"Not-Related"}
+{"text":"Children undergoing chemotherapy, postsurgical procedures and those with AIDS are at increased risk for developing this unique type of shock.","label":0,"label_text":"Not-Related"}
+{"text":"Nine eyes from 6 patients, 74 years to 90 years of age, referred by ophthalmologists for repair of cicatricial entropion after at least 2 years of twice-a-day application of dipivefrin.","label":1,"label_text":"Related"}
+{"text":"Levofloxacin-induced delirium with psychotic features.","label":1,"label_text":"Related"}
+{"text":"While thrombolysis is a first-line treatment option in massive PE and acute MI, cardiopulmonary resuscitation (CPR) has been regarded as a relative contraindication for thrombolysis because of the anticipated bleeding risk caused by traumatic cardiocompressions.","label":0,"label_text":"Not-Related"}
+{"text":"Idiosyncratic pulmonary reactions to nitrofurantoin are not unusual, often presenting as eosinophilic pneumonia.","label":1,"label_text":"Related"}
+{"text":"Phenytoin toxicity is an uncommon problem seen in clinical practice.","label":0,"label_text":"Not-Related"}
+{"text":"Despite premedication with dexamethasone prior to a second attempt at therapy, she again experienced similar symptoms after receiving 500 mL (78 mg) of cisplatin solution.","label":0,"label_text":"Not-Related"}
+{"text":"Ten days before hospitalization he had undergone minimally invasive cutaneous surgery for crusty lesions but had not received antibiotic prophylaxis.","label":0,"label_text":"Not-Related"}
+{"text":"Simultaneous scrofuloderma and intracranial tuberculomas: a rare presentation of systemic tuberculosis.","label":0,"label_text":"Not-Related"}
+{"text":"Insulin-induced lipohypertrophy: report of a case with histopathology.","label":1,"label_text":"Related"}
+{"text":"Methadone-induced myoclonus in advanced cancer.","label":1,"label_text":"Related"}
+{"text":"METHODS: Case reports and associated biopsy findings.","label":0,"label_text":"Not-Related"}
+{"text":"Two of the authors of the recent review were expert witnesses in the trial.","label":0,"label_text":"Not-Related"}
+{"text":"The case of an adult who developed both hepatic dysfunction and an impaired macrophage migration after exposure to cimetidine is discussed.","label":1,"label_text":"Related"}
+{"text":"Energy-dispersive X-ray analysis confirmed the presence of calcium.","label":0,"label_text":"Not-Related"}
+{"text":"As described in previous reports, the most common adverse effects are pain, inflammation, and induration at the injection site, occurring in approximately 20-60% of patients.","label":0,"label_text":"Not-Related"}
+{"text":"A 37 year woman developed neuroleptic induced parkinsonism that persisted long after the drug had been discontinued.","label":0,"label_text":"Not-Related"}
+{"text":"Physicians should be aware of the potentially lethal side effects of dapsone.","label":1,"label_text":"Related"}
+{"text":"However, in some patients, surgical removal of the gingival tissue overgrowth becomes necessary.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: This is a case report of a CPP treated by a pain physician who demonstrated aberrant drug-related behaviors and required large doses of controlled-release oxycodone.","label":0,"label_text":"Not-Related"}
+{"text":"In two cases, caspofungin was added as salvage treatment due to failure of trimethoprim-sulfametoxazole monotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"We report on two girls, 3 and 13 years old, with acute promyelocytic leukemia (APL) who were successfully treated with all-trans retinoic acid (ATRA) 45 mg\/m2\/day.","label":0,"label_text":"Not-Related"}
+{"text":"A review of the literature of 68 case reports of acute leukemia following ovarian cancer is presented and 3 new cases are reported.","label":0,"label_text":"Not-Related"}
+{"text":"Neuroimaging in both diseases is characterized by large demyelinating lesions in the spinal cord extending over several segments, and\/or in the brain often involving the locations of astrocytes water channels.","label":0,"label_text":"Not-Related"}
+{"text":"Both patients underwent successful thrombolysis after super-selective angiograms.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To report a case of Carbamazepine toxicity following the administration of Oxybutynin and Dantrolene.","label":1,"label_text":"Related"}
+{"text":"In view of the enormous, and potentially fatal, plasma concentration of the drug, charcoal haemoperfusion was undertaken as well as cysteamine therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Inhaled corticosteroids may cause various adverse effects ranging from irritation to severe anaphylactic reactions and systemic contact dermatitis.","label":0,"label_text":"Not-Related"}
+{"text":"Diagnosis was confirmed by histological and mycological examination.","label":0,"label_text":"Not-Related"}
+{"text":"The profession must assume responsibility for studies to determine the safety of the methods of application of the hydrogen peroxide, salt and baking soda mixtures and disseminate this information for the public interest.","label":0,"label_text":"Not-Related"}
+{"text":"Because of a recurrence of paroxysmal atrial fibrillation, the dose of the drug was increased to 1.4 g\/day; 24 hours later AVT with syncope developed but responded promptly to atropine.","label":0,"label_text":"Not-Related"}
+{"text":"Acute reversible ataxo-myoclonic encephalopathy with flecainide therapy.","label":1,"label_text":"Related"}
+{"text":"Gabapentin for the treatment of neuropathic pain in a pregnant horse.","label":0,"label_text":"Not-Related"}
+{"text":"For these reasons vasoconstrictor imidazoline containing solutions should be prescribed with caution and kept out of reach of children.","label":0,"label_text":"Not-Related"}
+{"text":"Many combinations of methotrexate and folic or folinic acid have been used to limit the side effects of methotrexate therapy in psoriasis or psoriatic arthropathy.","label":0,"label_text":"Not-Related"}
+{"text":"Overdose with chloral hydrate: a pharmacological and therapeutic review.","label":0,"label_text":"Not-Related"}
+{"text":"Interestingly, the patient's mother had also experienced a generalised pustular dermatosis associated with hypocalcaemia during oral contraceptive use, which was diagnosed clinically and histologically as impetigo herpetiformis.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of portopulmonary hypertension in which the pulmonary hypertension resolved after initial orthotopic liver transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"Interferon-alpha (IFN-alpha) may precipitate or exacerbate the occurrence of MPGN.","label":1,"label_text":"Related"}
+{"text":"We present a case of hemolytic-uremic syndrome that developed during the 4th cycle of combination chemotherapy with oxaliplatin, 5-fluorouracil and leucovorin.","label":1,"label_text":"Related"}
+{"text":"Subsequent scheduled phenobarbital administration allowed for a successful and orderly weaning of the continuous benzodiazepine infusion and adjunctive agents used in AWS management.","label":0,"label_text":"Not-Related"}
+{"text":"Physicians should be aware of the risk of severe AIHA in CLL patients with a history of AIHA or positivation of the DAT during previous fludarabine administration, or in case of secondary fixation of complement to the red cell membrane occurring during fludarabine treatment.","label":1,"label_text":"Related"}
+{"text":"Early diagnosis of osteonecrosis is important to prevent irreversible bone and joint destruction.","label":0,"label_text":"Not-Related"}
+{"text":"Following the institution of intravenous therapy with acyclovir, the patient developed fever, hemoptysis, and a pleural friction rub.","label":1,"label_text":"Related"}
+{"text":"OK-432 therapy is considered hopeful for treating viral skin diseases, even in immunosuppressed patients.","label":0,"label_text":"Not-Related"}
+{"text":"Three patients with T315I abl-mutated chronic myeloid leukemia (CML) or Philadelphia chromosome (Ph)-positive acute lymphocytic leukemia (ALL) have achieved clinical responses to doses of MK-04547 that are not associated with adverse events.","label":0,"label_text":"Not-Related"}
+{"text":"Imaging studies showed calcification and fibrosis of the involved muscles.","label":0,"label_text":"Not-Related"}
+{"text":"SUMMARY: A 29-year-old woman sought treatment from a pulmonologist for a dry, hacking, constant cough not relieved by fast-acting inhalers or narcotic cough medications that had lasted for three weeks.","label":0,"label_text":"Not-Related"}
+{"text":"A review of the literature suggests that this may be an unusual complication of thrombolytic therapy.","label":0,"label_text":"Not-Related"}
+{"text":"To our knowledge, this is the first report of this syndrome related to vinorelbine therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Carbamazepine was discontinued upon admission, and the patient was treated with oral lactulose.","label":0,"label_text":"Not-Related"}
+{"text":"The 9 other reported cases of D-penicillamine induced rapidly progressive glomerulonephritis have been reviewed.","label":1,"label_text":"Related"}
+{"text":"The right eye progressed to phthisis bulbi.","label":0,"label_text":"Not-Related"}
+{"text":"He was not immunocompromised, debilitated and had not had recent surgery.","label":0,"label_text":"Not-Related"}
+{"text":"We present two cases where successful thrombolysis of right heart thrombi and pulmonary embolism was accompanied by serious adverse events.","label":0,"label_text":"Not-Related"}
+{"text":"A 57-year-old woman with right bundle branch block +LPH and ventricular premature contractions developed complete heart block (CHB) following administration of disopyramide phosphate (Norpace).","label":1,"label_text":"Related"}
+{"text":"One percent lindane should continue to remain the preparation of choice for nearly all patients with scabies and lice, but dermatologists should appreciate that these views are not necessarily shared by all health professionals.","label":0,"label_text":"Not-Related"}
+{"text":"For drugs with a narrow therapeutic index such as chloroquine, recommended dosing regimens should be respected, and adequate information sources must be available where such drugs are dispensed by untrained personnel.","label":0,"label_text":"Not-Related"}
+{"text":"Ours is a 430-bed tertiary care teaching hospital, The Wellesley Hospital, Toronto, Ontario.","label":0,"label_text":"Not-Related"}
+{"text":"The development of safer and more effective means for VT control is progressing and is needed.","label":0,"label_text":"Not-Related"}
+{"text":"In one case, disulfiram was the only potential teratogen exposed to the fetus.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: We report the first case of gemcitabine-induced LABD.","label":1,"label_text":"Related"}
+{"text":"We reviewed the literature in an attempt to characterize the pattern and predictors of TMP\/SMX-induced aseptic meningitis.","label":1,"label_text":"Related"}
+{"text":"Treatment with terbutaline was continued for 13 days and was well tolerated.","label":0,"label_text":"Not-Related"}
+{"text":"None of the patients had loco-regional recurrence.","label":0,"label_text":"Not-Related"}
+{"text":"Interestingly in one of our patients, the arthritis was almost asymptomatic and did not spread to other organs.","label":0,"label_text":"Not-Related"}
+{"text":"Investigations in two patients have revealed excessive renal loss of magnesium.","label":0,"label_text":"Not-Related"}
+{"text":"Reports of colonic perforation as a result of the administration of calcium polystyrene sulfonate and sorbitol are rare.","label":1,"label_text":"Related"}
+{"text":"We present a case of a 16-year-old female with Graves' disease who presented with massive bone marrow plasmocytosis mimicking multiple myeloma.","label":0,"label_text":"Not-Related"}
+{"text":"Microbiological and histopathological confirmation of acanthamebic keratitis.","label":0,"label_text":"Not-Related"}
+{"text":"One of the three patients underwent aortic valve replacement three times and progression of the prosthesis dehiscence was arrested with the use of corticosteroids.","label":0,"label_text":"Not-Related"}
+{"text":"This case of linezolid-associated acute interstitial nephritis within the context of a drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a patient treated with linezolid raises concerns about the presumed renal safety of this drug.","label":1,"label_text":"Related"}
+{"text":"Restless legs syndrome and periodic limb movements during sleep probably associated with olanzapine.","label":1,"label_text":"Related"}
+{"text":"Unusual coronary artery aneurysm and acute myocardial infarction in a middle-aged man with systemic lupus erythematosus.","label":0,"label_text":"Not-Related"}
+{"text":"We report two cases of cerebrospinal fluid eosinophilia (CSFE) secondary to the intraventricular administration of vancomycin.","label":1,"label_text":"Related"}
+{"text":"Localized herpes simplex (HSV) type II following intra-articular corticosteroid injection is remarkable.","label":0,"label_text":"Not-Related"}
+{"text":"Radiation-induced osteosarcoma arising 20 years after the treatment of Ewing's sarcoma.","label":0,"label_text":"Not-Related"}
+{"text":"Effectiveness of milnacipran for the treatment of chronic pain: a case series.","label":0,"label_text":"Not-Related"}
+{"text":"Complete regression of the CIN was observable after 60 days of therapy.","label":0,"label_text":"Not-Related"}
+{"text":"We suggest, however, that routine screening in such patients may be important.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: The mean age was 44 years (range: 23-67) and no sexual predisposition was noted.","label":0,"label_text":"Not-Related"}
+{"text":"We suspect that improper technique resulted in an inadvertent administration of an intrathecal baclofen bolus.","label":0,"label_text":"Not-Related"}
+{"text":"We report a 45-year-old Chinese man with CML and chronic hepatitis B virus infection, on imatinib treatment, presenting with herpetic rash and acute liver failure.","label":1,"label_text":"Related"}
+{"text":"Corneal endothelial dysfunction associated with amantadine toxicity.","label":1,"label_text":"Related"}
+{"text":"The side effects of MMF, such as bone marrow toxicity, have been reported.","label":1,"label_text":"Related"}
+{"text":"They continued to rise for five more days before salicylate hepatotoxicity was suspected.","label":1,"label_text":"Related"}
+{"text":"Oral administration of prednisolone at a daily dose of 30 mg (0.4 mg\/kg) was effective to improve their renal function.","label":0,"label_text":"Not-Related"}
+{"text":"All four patients had been taking high doses of niacin (3.0-4.5 g daily) before the onset of symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"There was no statistically significant difference between the incidence of the total CNS complications among the different organ transplant groups (p value > 0.10), but there was a statistically significant difference in the systemic complications among the organ transplant groups (p value < 0.001).","label":0,"label_text":"Not-Related"}
+{"text":"A case of acute subdural haematoma originating spontaneously from an angiomatous meningioma in a patient receiving prophylactic aspirin therapy is presented.","label":1,"label_text":"Related"}
+{"text":"This paper reports a case of fatal perhexiline maleate liver injury.","label":1,"label_text":"Related"}
+{"text":"Disulfiram-induced hepatitis.","label":1,"label_text":"Related"}
+{"text":"These patients were treated by the continuous administration of an estrogen-progestogen combination for 6 months.","label":0,"label_text":"Not-Related"}
+{"text":"Sequential patients arriving to our center within 3 hours of stroke onset who were treated with intravenous alteplase were screened for possible additional intra-arterial therapy using noninvasive neuroimaging.","label":0,"label_text":"Not-Related"}
+{"text":"Patient survival depends on prompt referral to a specialist burns unit.","label":0,"label_text":"Not-Related"}
+{"text":"A patient using ziprasidone with polydipsia, seizure, hyponatremia and rhabdomyolysis.","label":0,"label_text":"Not-Related"}
+{"text":"His recovery was uneventful.","label":0,"label_text":"Not-Related"}
+{"text":"Late repeat restenosis was treated with a third (Taxus, Boston Scientific, Maple Grove, Minnesota, USA) stent that was deployed through the previously implanted stent struts.","label":0,"label_text":"Not-Related"}
+{"text":"Eight of the children were exposed to lead-based paint, with seven due to dust from sanded lead paint during house renovations.","label":0,"label_text":"Not-Related"}
+{"text":"Her condition has improved with progesterone therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Moreover, treatment with immunosuppressive drugs such as cyclosporine, cisplatin, tacrolimus, and interferon-alpha can induce a condition resembling RPLS.","label":1,"label_text":"Related"}
+{"text":"Due to Quetiapine's particulars and the promising receptor profile concerning addiction medicine, we set out to examine the tolerability and efficacy concerning relapse prevention of withdrawn alcoholics suffering from craving and affective symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"The posterior hyaloid became taut and partially detached after the third injection and was almost completely detached 1 year later.","label":0,"label_text":"Not-Related"}
+{"text":"This observation indicates the complex effect of HIV on joint inflammation.","label":0,"label_text":"Not-Related"}
+{"text":"The treatment was given on an outpatient basis without requiring prolonged patient sedation or immobilization.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of AILD in an 80-year-old male who presented with a generalized pruritic maculopapular eruption and fever following doxycycline administration.","label":1,"label_text":"Related"}
+{"text":"In both our cases, such a regimen did not prevent the occurrence of endometrial polyps which, although histologically benign, were usually large and thought clinically to be malignant.","label":0,"label_text":"Not-Related"}
+{"text":"Thrombolysis was administered and the patient recovered uneventfully.","label":0,"label_text":"Not-Related"}
+{"text":"In transplant recipients, such tumors are more common and more aggressive but their treatment does not differ from the treatment of Merkel cell carcinomas in the general population.","label":0,"label_text":"Not-Related"}
+{"text":"Increasing evidence suggests that neurohumoral manifestations of heart failure may lead to insulin resistance, predisposing patients with heart failure to the development of glucose intolerance or worsening of existing diabetes.","label":0,"label_text":"Not-Related"}
+{"text":"Both patients had atrial flutter with 2 to 1 atrioventricular block that evolved into 1 to 1 atrioventricular conduction.","label":0,"label_text":"Not-Related"}
+{"text":"Measurements of the peripheral arterial circulation were made using the Doppler ultrasonic velocity detector.","label":0,"label_text":"Not-Related"}
+{"text":"Also required are high index of suspicion and importantly serum levels of aflatoxin.","label":0,"label_text":"Not-Related"}
+{"text":"Electrical, chemical, and thermal agents are the main causative agents of these burns.","label":0,"label_text":"Not-Related"}
+{"text":"Additionally, her clinical course was complicated with adenovirus-associated haemorrhagic cystitis and viraemia.","label":0,"label_text":"Not-Related"}
+{"text":"This is the first reported case of suspected DIAN due to cefuroxime.","label":1,"label_text":"Related"}
+{"text":"Clinical aspects of Candida infection in denture wearers.","label":0,"label_text":"Not-Related"}
+{"text":"Two years later, 24 hours following an increase in the dose of disopyramide from 300 to 600 mg\/day, AVT with syncope occurred; isoproterenol abolished the arrhythmia instantly.","label":1,"label_text":"Related"}
+{"text":"A 13-month-old child with lamellar ichthyosis and numerous cutaneous and systemic infections died following an abrupt episode of severe hypotension.","label":0,"label_text":"Not-Related"}
+{"text":"Her condition improved, and she was discharged after 22 days.","label":0,"label_text":"Not-Related"}
+{"text":"The rash seen in this patient, who was treated with cephalexin, may be similar to the rash seen with ampicillin treatment of patients with infectious mononucleosis.","label":1,"label_text":"Related"}
+{"text":"The patient experienced hallucinations, agitation, vomiting, tachycardia and seizures after ingestion of 1050 (48 mg\/kg) of extended-release bupropion.","label":1,"label_text":"Related"}
+{"text":"Reduced vision secondary to pigmented cellular membranes on silicone intraocular lenses.","label":0,"label_text":"Not-Related"}
+{"text":"Fungal infections were more likely to be associated with abdominal devices, to have a local rather than systemic infection, and to have a longer duration from the original implant to presentation.","label":0,"label_text":"Not-Related"}
+{"text":"His diagnosis was reconfirmed and then treated with Pentostatin.","label":0,"label_text":"Not-Related"}
+{"text":"Marginal crack after intravitreal bevacizumab for myopic choroidal neovascularization.","label":0,"label_text":"Not-Related"}
+{"text":"Adverse effect of verapamil in myasthenia gravis.","label":0,"label_text":"Not-Related"}
+{"text":"Twenty-six (of 40 successful) patients indicated that they favored the night-time regimen mainly because it was less complicated.","label":0,"label_text":"Not-Related"}
+{"text":"This case had radiation fibrosis, so we suggest that radiation fibrosis may be another contributor of the occurrence of ILD in patients taking erlotinib.","label":1,"label_text":"Related"}
+{"text":"She responded well to Sodium valproate.","label":0,"label_text":"Not-Related"}
+{"text":"Laboratory investigation confirmed prior exposure to CMV, EBV and HSV and suggested drug-induced immunological suppression.","label":0,"label_text":"Not-Related"}
+{"text":"The propensity of this disease to simulate gynecological malignancies has been described previously.","label":0,"label_text":"Not-Related"}
+{"text":"The day after the infusion, she no longer complained of diplopia, and her ophthalmoplegia had improved dramatically.","label":0,"label_text":"Not-Related"}
+{"text":"Valproate-induced hyperammonemia as a cause of altered mental status.","label":1,"label_text":"Related"}
+{"text":"Two of the patients who had acute renal failure while receiving ACE-inhibitor therapy experienced a recurrence when rechallenged with such therapy.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: We recently experienced a case of fatal erlotinib-induced ILD, diagnosed based on clinical and radiologic findings, which occurred in a patient with radiation fibrosis.","label":1,"label_text":"Related"}
+{"text":"However, hepatotoxicity is extremely rare.","label":0,"label_text":"Not-Related"}
+{"text":"They also raise issues of patient education for self medication and access to emergency dental services outside normal working hours.","label":0,"label_text":"Not-Related"}
+{"text":"Patient beliefs that prescribed medication has limitations and that natural products are safe contributed to the use of herbal remedies.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Herpes zoster reactivation may occur following LASIK.","label":0,"label_text":"Not-Related"}
+{"text":"Physicians treating patients with methotrexate for juvenile rheumatoid arthritis must be aware of this extraarticular side effect.","label":1,"label_text":"Related"}
+{"text":"Iatrogenic Cushing syndrome after epidural triamcinolone injections in an HIV type 1-infected patient receiving therapy with ritonavir-lopinavir.","label":1,"label_text":"Related"}
+{"text":"DISCUSSION: To our knowledge, this is the first case report illustrating neuralgic amyotrophy triggered by exposure to the antibiotics vancomycin, tobramycin, and piperacillin\/tazobactam.","label":1,"label_text":"Related"}
+{"text":"Clinicians need to be aware of this potential side effect especially in children undergoing major surgery.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVES: To describe therapeutic cannabis use among patients with chronic pain.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a case of acute gouty arthritis in a 71-year-old man with chronic renal failure who was treated with RFA for a HCC lesion and who had hepatitis B-associated cirrhosis and mild renal insufficiency.","label":0,"label_text":"Not-Related"}
+{"text":"We present four cases of iatrogenic epidural spinal abscess directly caused by externally introduced catheters or probes.","label":0,"label_text":"Not-Related"}
+{"text":"Successful desensitization to high-dose methotrexate after systemic anaphylaxis.","label":1,"label_text":"Related"}
+{"text":"Effect of clozapine in severe tardive dyskinesia: a case report.","label":0,"label_text":"Not-Related"}
+{"text":"A complete remission was achieved twice.","label":0,"label_text":"Not-Related"}
+{"text":"A 7-year-old with congenital toxoplasmosis who took pyrimethamine and sulfadiazine for reactivated chorioretinitis developed fever, severe cutaneous involvement, swelling, abdominal pain and transaminitis, persisting weeks after withholding medicines.","label":1,"label_text":"Related"}
+{"text":"We report the case of a 27-year-old Indian woman who developed maculopapular rash and angioedema secondary to carbamazepine administration.","label":1,"label_text":"Related"}
+{"text":"The treatments have been reasonably well tolerated with some acute skin toxicity.","label":0,"label_text":"Not-Related"}
+{"text":"We report an 18-year-old male patient who developed chronic hepatitis C after blood transfusion and had testicular dysfunction after irradiation for a testicular relapse of childhood acute lymphocytic leukemia after cessation of maintenance therapy, and the initiation of testosterone replacement therapy at puberty.","label":0,"label_text":"Not-Related"}
+{"text":"The patients differed with regard to risk; one patient had existing cardiopulmonary disease, and the other was free of such risk factors except liver disease.","label":0,"label_text":"Not-Related"}
+{"text":"Based on these data, we conclude that PSL therapy can ameliorate primary nephrotic syndrome in patients over the age of eighty years.","label":0,"label_text":"Not-Related"}
+{"text":"Foscarnet-induced severe hypomagnesemia and other electrolyte disorders.","label":1,"label_text":"Related"}
+{"text":"Leukopenia and agranulocytosis are well reported and dangerous haematological side-effects associated with the use of typical and atypical antipsychotics.","label":0,"label_text":"Not-Related"}
+{"text":"While doxorubicin was administered, the patient presented thoracic pain and breathing distress due to superior vena cava perforation by the central catheter and subsequent extravasation of the drug into the mediastinum.","label":1,"label_text":"Related"}
+{"text":"Two unsuccessful attempts were made to repair the valve which was finally replaced, requiring cardiopulmonary bypass of 317 min.","label":0,"label_text":"Not-Related"}
+{"text":"Lorazepam 2 mg was given with significant improvement.","label":0,"label_text":"Not-Related"}
+{"text":"Magnetic resonance imaging revealed regional kyphosis and large swollen paraspinal muscles impinging on the spinal cord without epidural hematoma.","label":0,"label_text":"Not-Related"}
+{"text":"Awareness of this potentially serious complication of chemotherapy can facilitate timely recognition of leukoencephalopathy with the use of magnetic resonance imaging.","label":0,"label_text":"Not-Related"}
+{"text":"On day 1 of admission, the patient exhibited a diffuse urticarial rash over his trunk and extremities.","label":0,"label_text":"Not-Related"}
+{"text":"Clozapine is the least likely anti-psychotic to induce extrapyramidal symptoms (EPS).","label":0,"label_text":"Not-Related"}
+{"text":"Upon rechallenge with clomiphene 3 months later, she again developed bilateral anterior uveitis.","label":0,"label_text":"Not-Related"}
+{"text":"All six patients have 6\/6 best corrected vision.","label":0,"label_text":"Not-Related"}
+{"text":"We describe the infectious toxicities experienced by the first two patients in our institution treated with dexamethasone (10 mg\/m(2)\/day for 4 weeks with gradual tapering) during induction according to the dexamethasone arm of BFM 2000 and review the relevant literature that suggests an increased risk of infectious complications with dexamethasone.","label":1,"label_text":"Related"}
+{"text":"In animals, increased dietary sodium reduces renal toxicity.","label":0,"label_text":"Not-Related"}
+{"text":"We report marked QT prolongation and torsades de pointes in a setting of flash pulmonary edema resulting from acute myocardial ischemia in a patient who was being treated with dofetilide for atrial fibrillation.","label":1,"label_text":"Related"}
+{"text":"The day after methotrexate administration, the patient complained of severe back pain and urinary retention.","label":1,"label_text":"Related"}
+{"text":"An associated transient pancreatic dysfunction was also noted.","label":0,"label_text":"Not-Related"}
+{"text":"A 61-year-old man developed clinical lupus syndrome with positive antinuclear antibody, positive lupus erythematosus (LE) cell preparation, and diffuse proliferative glomerulonephritis following 26 months of procainamide therapy.","label":1,"label_text":"Related"}
+{"text":"Since an interaction between fluvoxamine and tizanidine, prescribed by another clinic, was suspected, fluvoxamine was replaced with milnacipran 50 mg day(-1).","label":0,"label_text":"Not-Related"}
+{"text":"Heightened seizure susceptibility associated with brain dermoid cyst and the administration of human chorionic gonadotropin (hCG).","label":0,"label_text":"Not-Related"}
+{"text":"Colonic necrosis is known as a rare complication following the administration of Kayexalate (sodium polystryrene sulfonate) in sorbitol.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: The new quinolone derivatives (levofloxacin, sparfloxacin, grepafloxacin, trovafloxacin, gatifloxacin and moxifloxacin), also called gyrase inhibitors, are known for their potential to cause central nervous system-related adverse effects, including headache, dizziness and insomnia.","label":1,"label_text":"Related"}
+{"text":"Severe hepatitis caused by cyproterone acetate.","label":1,"label_text":"Related"}
+{"text":"Transient TRH deficiency after prolonged thyroid hormone therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Management of the hypertension required large doses of antihypertensive agents, including sodium nitroprusside, for six postoperative days.","label":0,"label_text":"Not-Related"}
+{"text":"Use of high-dose intravenous immunoglobulin in systemic lupus erythematosus: report of three cases.","label":0,"label_text":"Not-Related"}
+{"text":"Operative mortality was 64% in the prosthetic mitral thrombosis and 20% in the aortic one.","label":0,"label_text":"Not-Related"}
+{"text":"Two-thirds of the chronic cases improved markedly.","label":0,"label_text":"Not-Related"}
+{"text":"Although both the spontaneous occurrence of SLE and the psychosis as a sign of CNS involvement of SLE cannot be excluded, SLE could be considered as an adverse effect of carbamazepine.","label":1,"label_text":"Related"}
+{"text":"This is the first CT demonstration of widely disseminated living cysticerci in brain and muscles.","label":0,"label_text":"Not-Related"}
+{"text":"Five months later the patient was diagnosed as MH-susceptible by the in vitro caffeine and halothane contracture test.","label":0,"label_text":"Not-Related"}
+{"text":"Cultures of both the cerebrospinal fluid and aspirated liver abscess isolated MRSA.","label":0,"label_text":"Not-Related"}
+{"text":"A patient with diffuse and focal cerebral dysfunction was found to have absent peripheral pulses.","label":0,"label_text":"Not-Related"}
+{"text":"PTH was significantly higher in these patients than in 150 normal subjects.","label":0,"label_text":"Not-Related"}
+{"text":"This case report describes a patient with Turner's syndrome receiving systemic androgen therapy who experienced marked gingival enlargement, bleeding, and discomfort.","label":0,"label_text":"Not-Related"}
+{"text":"We cared for a patient with progressive renal impairment who presented with blurred vision, QRS broadening and cardiac failure due to chronic cibenzoline intoxication.","label":1,"label_text":"Related"}
+{"text":"Given the immune-mediated processes in psoriasis and psoriatic arthritis, patients with these disorders may benefit from infliximab therapy but may also suffer from an increased risk of infection.","label":0,"label_text":"Not-Related"}
+{"text":"Before the myocardial infarction, the patient was in good condition, normotensive, non-diabetic, non-obese.","label":0,"label_text":"Not-Related"}
+{"text":"The patient's other comorbidities and medications have not been suggested as possible interactions with sertraline that can cause rhabdomyolysis.","label":1,"label_text":"Related"}
+{"text":"No severe side effects were observed in the liver, kidney, blood or the eyeground.","label":0,"label_text":"Not-Related"}
+{"text":"Although the treatment of choice for autoimmune hepatitis is glucocorticoids, their side effects make long-term use undesirable.","label":0,"label_text":"Not-Related"}
+{"text":"This case report is the first to describe a possible interaction with glipizide.","label":0,"label_text":"Not-Related"}
+{"text":"Immediately after the intubation, she suffered cardiac arrest.","label":0,"label_text":"Not-Related"}
+{"text":"While he agrees that systemic antibiotics should be avoided, he also would not prescribe ear drops.","label":0,"label_text":"Not-Related"}
+{"text":"We report two adults who received gabapentin (GBP) and subsequently developed behavioural side effects.","label":1,"label_text":"Related"}
+{"text":"Of these 75% were males.","label":0,"label_text":"Not-Related"}
+{"text":"After other potential causes of liver toxicity were excluded, TMP-SMX was determined to be the cause of his acute liver toxicity.","label":1,"label_text":"Related"}
+{"text":"Prompt diagnosis using histology, serology, and PCR analysis allows prompt introduction of therapy and an improved prognosis.","label":0,"label_text":"Not-Related"}
+{"text":"The criterion for TD was a score of > or = 3 on one item or 2 on two or more items of the ESRS.","label":0,"label_text":"Not-Related"}
+{"text":"He received dimercaprol (BAL) and calcium disodium edetate (CaEDTA) for two five days session.","label":0,"label_text":"Not-Related"}
+{"text":"Chest wall actinomycosis in association with the use of an intra-uterine device.","label":0,"label_text":"Not-Related"}
+{"text":"Agranulocytosis is a disorder characterized by a severe decrease in the number of granulocytes in blood, that frequently occurs as an adverse reaction to some drugs.","label":0,"label_text":"Not-Related"}
+{"text":"Laboratory tests showed creatine kinase 144600 IU\/L (reference range 24-195), myoglobin >3000 ng\/mL (28-72), lactate dehydrogenase 7157 IU\/L (230-460), aspartate aminotransferase 1115 IU\/L (10-35), and alanine aminotransferase 205 IU\/L (10-35).","label":0,"label_text":"Not-Related"}
+{"text":"A more serious development of adrenal insufficiency may occur upon the improper replacement of systemic steroids.","label":0,"label_text":"Not-Related"}
+{"text":"It may be due to several causes with different outcomes.","label":0,"label_text":"Not-Related"}
+{"text":"Both amoxapine and its active and major metabolite, 8-OH-amoxapine, appeared in breast milk.","label":0,"label_text":"Not-Related"}
+{"text":"Niacin maculopathy.","label":1,"label_text":"Related"}
+{"text":"We describe a case of life-threatening hyponatremia associated with sibutramine use in an obese woman.","label":1,"label_text":"Related"}
+{"text":"We describe a case of cholangiocarcinoma in a young woman, who presented with cholestatic jaundice following oral contraceptive ingestion.","label":0,"label_text":"Not-Related"}
+{"text":"True thymic hyperplasia is rare in adults.","label":0,"label_text":"Not-Related"}
+{"text":"No other cause of abdominal pain was identified.","label":0,"label_text":"Not-Related"}
+{"text":"Lead poisoning and recurrent abdominal pain.","label":0,"label_text":"Not-Related"}
+{"text":"How low can you go? Use of very low dosage of gold in patients with mucocutaneous reactions.","label":1,"label_text":"Related"}
+{"text":"Captopril-associated \"pseudocholangitis'.","label":1,"label_text":"Related"}
+{"text":"The potential for fomepizole to inhibit retinol dehydrogenase, an isoenzyme of alcohol dehydrogenase essential to vision, did not appear to be clinically significant in this symptomatic methanol-poisoned patient.","label":0,"label_text":"Not-Related"}
+{"text":"Vancomycin is the most frequently implicated drug, but other agents have been reported to cause LABD.","label":1,"label_text":"Related"}
+{"text":"Encephalopathy and seizures induced by intravesical alum irrigations.","label":1,"label_text":"Related"}
+{"text":"Radiography disclosed a lumbosacral intradural tumor.","label":0,"label_text":"Not-Related"}
+{"text":"C. striatum should be recognized as a potential pathogen in both immunocompromised and normal hosts in the appropriate circumstances, and appropriate antimicrobial therapy can quickly lead to resolution of infection.","label":0,"label_text":"Not-Related"}
+{"text":"Topical anesthesia-induced keratopathy after laser-assisted subepithelial keratectomy.","label":0,"label_text":"Not-Related"}
+{"text":"Indium-111 platelet scintigraphy in a patient with chronic disseminated intravascular coagulation.","label":0,"label_text":"Not-Related"}
+{"text":"Leukemogenesis related to chemotherapy of ovarian carcinoma: a review with three new case reports.","label":0,"label_text":"Not-Related"}
+{"text":"CASE SUMMARIES: Two patients who received ifosfamide-containing chemotherapy developed NCSE.","label":1,"label_text":"Related"}
+{"text":"Bilateral anterior uveitis associated with clomiphene citrate.","label":1,"label_text":"Related"}
+{"text":"We report for the first time the successful treatment of a patient who developed compensatory hyperhidrosis following sympathectomy using video assisted extension of the sympathectomy by application of botulinum toxin (BTX-A).","label":0,"label_text":"Not-Related"}
+{"text":"This article reports the occurrence of rifampin-associated thrombocytopenia in an indigent patient after a four-month lapse in therapy for pulmonary tuberculosis.","label":1,"label_text":"Related"}
+{"text":"The objective of this paper is to report 5 cases of rhabdomyolysis (RML) in patients with acute leukemia (AL).","label":0,"label_text":"Not-Related"}
+{"text":"Metoclopramide-induced parkinsonism is not rare, and appropriate dose reduction in patients with renal failure will help reduce the incidence of this morbidity.","label":1,"label_text":"Related"}
+{"text":"A 54-year-old man, treated with amiodarone, developed thyrotoxicosis.","label":1,"label_text":"Related"}
+{"text":"These areas were subject to repeated exposure to solvents.","label":0,"label_text":"Not-Related"}
+{"text":"Vasomotor reactions after gold sodium thiomalate are well recognized.","label":1,"label_text":"Related"}
+{"text":"Neuralgic amyotrophy associated with antibiotic therapy.","label":0,"label_text":"Not-Related"}
+{"text":"We report a patient with chronic renal failure and ischemic heart disease who developed clinically significant methemoglobinemia after an axillary block with bupivacaine and additional injection of lidocaine in the operative field.","label":1,"label_text":"Related"}
+{"text":"It is severe enough to require discontinuation of therapy in 1-10 percent of patients.","label":0,"label_text":"Not-Related"}
+{"text":"Uveitis during treatment of disseminated Mycobacterium avium-intracellulare complex infection with the combination of rifabutin, clarithromycin and ethambutol.","label":1,"label_text":"Related"}
+{"text":"Simvastatin-induced rhabdomyolysis following cyclosporine treatment for uveitis.","label":1,"label_text":"Related"}
+{"text":"Transient bullous dermolysis of the newborn consists of congenital skin defects and a tendency for blistering of the skin and mucous membranes during the neonatal period.","label":0,"label_text":"Not-Related"}
+{"text":"We now report the first known cancer patient who developed life-threatening complications after treatment with topical 5-FU and was shown subsequently to have profound DPD deficiency.","label":1,"label_text":"Related"}
+{"text":"A case report and review of the literature.","label":0,"label_text":"Not-Related"}
+{"text":"Drug-induced eosinophilia is a non-dose-dependent side effect of clozapine.","label":1,"label_text":"Related"}
+{"text":"Antibiotic treatment should be continued.","label":0,"label_text":"Not-Related"}
+{"text":"The main concern is hypoglycemia, which can cause sudden incapacitation.","label":0,"label_text":"Not-Related"}
+{"text":"During IFN therapy, serum aminotransferases fell within the normal range and viremia (serum HCV-RNA) became negative after one year.","label":0,"label_text":"Not-Related"}
+{"text":"Because neurologic toxicity is becoming more recognized and DPD affects the catabolism of 5-FU, we discuss management issues and the use of new DPD inhibitors.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Withdrawal of the drug and initiation of corticosteroid drops resulted in prompt resolution of the choroidal detachment.","label":0,"label_text":"Not-Related"}
+{"text":"Histologically, the stratum corneum was thickened, with persistent nuclei together with countless small basophilic granules.","label":0,"label_text":"Not-Related"}
+{"text":"Spinal epidural lipomatosis: a case study.","label":0,"label_text":"Not-Related"}
+{"text":"No evidence of myocardial infarction was detected.","label":0,"label_text":"Not-Related"}
+{"text":"Botulinum toxin has been used in sporadic cases and seems to produce good results.","label":0,"label_text":"Not-Related"}
+{"text":"The association of infiltrative ophthalmopathy with primary hypothyroidism is uncommon.","label":0,"label_text":"Not-Related"}
+{"text":"We meningitis and epidural abscess after spinal bacteraemic patient.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of late cerebral toxoplasmosis reactivation, which was probably triggered by a brief course of corticosteroids, administered for chronic graft-versus-host disease (cGVHD).","label":0,"label_text":"Not-Related"}
+{"text":"Angioedema and dysphagia caused by contact allergy to inhaled budesonide.","label":1,"label_text":"Related"}
+{"text":"Chickenpox follows a severe and often fatal course in adults with renal transplants.","label":0,"label_text":"Not-Related"}
+{"text":"A few non-gestational cases due to oral contraceptive use have also been reported.","label":0,"label_text":"Not-Related"}
+{"text":"In the transplantation literature, MMF has been noted to lower red blood cell counts.","label":0,"label_text":"Not-Related"}
+{"text":"EMG and NCV results and neurologic examination were suggestive for Guillain-Barre.","label":0,"label_text":"Not-Related"}
+{"text":"In addition, AZA probably potentiated susceptibility to this viral infection and may have inhibited adequate immunological defense.","label":0,"label_text":"Not-Related"}
+{"text":"Pseudomembranous colitis in a leukaemia unit: a report of five fatal cases.","label":0,"label_text":"Not-Related"}
+{"text":"Case report with neuropathologic findings.","label":0,"label_text":"Not-Related"}
+{"text":"Patients were injected with 2 mg\/kg of sodium porfimer.","label":0,"label_text":"Not-Related"}
+{"text":"Protease inhibitors (ritonavir and saquinavir) were added to the treatment and the patient developed progressive ataxia related to carbamazepine toxicity.","label":1,"label_text":"Related"}
+{"text":"Although cytarabine exhibits pronounced in vitro virucidal activity against herpes viruses and has been successfully used in clinical treatment of severe herpesvirus infections, the present findings and a review of the recent literature cast doubt on the antiviral effectiveness of this drug, particularly in already immunosuppressed patients, and suggest instead that such patients actually have an increased risk for development of disseminated herpesvirus infection owing to further depression of host defenses by the drug.","label":0,"label_text":"Not-Related"}
+{"text":"Toxic epidermal necrolysis, a life-threatening reaction to certain types of drugs, is characterised by epidermal sloughing of more than 30% of the total body surface area.","label":0,"label_text":"Not-Related"}
+{"text":"During the anti-tuberculous therapy, visual loss can be related to ethambutol toxicity or the tuberculosis infection itself.","label":1,"label_text":"Related"}
+{"text":"Granulomas and Histoplasma organisms were found in the histologic sections of the marrow aspirate.","label":0,"label_text":"Not-Related"}
+{"text":"Acute renal failure in a patient treated by continuous povidone-iodine mediastinal irrigation.","label":1,"label_text":"Related"}
+{"text":"Total blindness with a transient tonic pupillary response, denervation supersensitivity, and abnormal visual-evoked potentials developed in a 54-year-old man after the use of quinine sulfate for leg cramps.","label":1,"label_text":"Related"}
+{"text":"Therefore, clinicians should pay close attention to possible onset of RD in patients with multiple risk factors for TD, even when SDA therapy is used.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: Atypical antipsychotic-induced diabetes does not always take a \"type 2\" presentation in which weight gain and insulin resistance are implicated.","label":0,"label_text":"Not-Related"}
+{"text":"The side effects in all patients have included varying degrees of anorexia, fatigue, ipsilateral forehead dermatitis, blepharitis, and conjunctivitis.","label":0,"label_text":"Not-Related"}
+{"text":"The observations suggest that testicular swelling and pain are side effects of desipramine.","label":1,"label_text":"Related"}
+{"text":"Relief by naloxone of morphine-induced spasm of the sphincter of Oddi in a post-cholecystectomy patient.","label":1,"label_text":"Related"}
+{"text":"In this report, a patient who had undergone a renal transplantation as a result of malignant hypertension, and who was on immunosuppressive therapy consisting of cyclosporin, prednisone and azathioprine, developed thrombosis of the central retinal vein 5 years following the transplantation.","label":1,"label_text":"Related"}
+{"text":"However, prolongation of 5-FU half-life and an increase in INR have been reported with the concurrent use of 5-FU and warfarin.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: Infectious endophthalmitis is a potential complication of intravitreal bevacizumab injection.","label":1,"label_text":"Related"}
+{"text":"Though the syndrome was suspected early, attempts at reversing the hematologic and renal abnormalities were unsuccessful.","label":0,"label_text":"Not-Related"}
+{"text":"All psychotropic medications were held except for a benzodiazepine.","label":0,"label_text":"Not-Related"}
+{"text":"At 26 weeks' gestation, she was transferred to our center.","label":0,"label_text":"Not-Related"}
+{"text":"Conditioning as an adjunct in the pharmacotherapy of lupus erythematosus.","label":0,"label_text":"Not-Related"}
+{"text":"Prior to beginning therapy with these antiretrovirals, he was receiving VPA 250 mg 3 times daily, with his most recent VPA concentration measured at 495 micromol\/L.","label":0,"label_text":"Not-Related"}
+{"text":"The thrombus was disrupted during cardiopulmonary resuscitation.","label":0,"label_text":"Not-Related"}
+{"text":"Paradoxical cerebral cortical hyperexcitability following flupirtine overdose.","label":1,"label_text":"Related"}
+{"text":"Treatment of reflex sympathetic dystrophy (RSD) is primarily surgical.","label":0,"label_text":"Not-Related"}
+{"text":"Following the institution of intravenous therapy with acyclovir, the patient developed fever, hemoptysis, and a pleural friction rub.","label":1,"label_text":"Related"}
+{"text":"We report a 16-year-old male who developed nephrotic syndrome related to membranous glomerulopathy with clinical and serological evidence of systemic lupus erythematosus after treatment with griseofulvin.","label":1,"label_text":"Related"}
+{"text":"We believe that these skin eruptions belong to a spectrum of neutrophilic dermatoses that can be induced or aggravated by G-CSF therapy.","label":1,"label_text":"Related"}
+{"text":"The aim of this study was to evaluate whether corticosteroid use is the etiological agent in acute pancreatitis in patients with systemic lupus erythematosus, or whether it is related to the underlying connective tissue disorder.","label":0,"label_text":"Not-Related"}
+{"text":"An association of granulocytopenia, eosinophilia, skin reaction and hepatitis during propylthiouracil (PTU) therapy for thyrotoxicosis in a 47 year old black female is reported.","label":1,"label_text":"Related"}
+{"text":"DESIGN: Retrospective case review.","label":0,"label_text":"Not-Related"}
+{"text":"Illness was severe in all three patients and one patient died even after initiation of doxycycline.","label":0,"label_text":"Not-Related"}
+{"text":"Relatively high levels of morphine-6-glucuronide were measured and all symptoms resolved promptly as the concentration of this metabolite declined.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of acute hyperphosphatemia secondary to rectal administration of sodium phosphate and sodium biphosphate (Fleet enema).","label":1,"label_text":"Related"}
+{"text":"This syndrome has been previously reported following cisplatin-based chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Tooth brushing-induced seizures: a case report.","label":0,"label_text":"Not-Related"}
+{"text":"The INR should be monitored more frequently when bosentan is initiated, adjusted, or discontinued in patients taking warfarin.","label":0,"label_text":"Not-Related"}
+{"text":"Successful treatment using a jet-injection device.","label":0,"label_text":"Not-Related"}
+{"text":"Somatostatin could also be helpful in bilio-pancreato-intestinal fistula, but in this case its advantage over elective surgical treatment remains to be confirmed.","label":0,"label_text":"Not-Related"}
+{"text":"Cytomegalovirus is a common infection worldwide and in the immunocompromised individual it can be a major cause of morbidity and mortality.","label":0,"label_text":"Not-Related"}
+{"text":"While most physicians are aware of heparin-induced thrombocytopenia and skin necrosis, the association of heparin and hyperkalemia is less well recognized.","label":1,"label_text":"Related"}
+{"text":"We report on two patients with PPG following breast surgery who were successfully treated with low-dose cyclosporin (2.5-5 mg\/kg per day).","label":0,"label_text":"Not-Related"}
+{"text":"In recent years, the association between breast and endometrial cancer has been the subject of many studies.","label":0,"label_text":"Not-Related"}
+{"text":"Her course was further complicated by exudative pleural effusion and pneumonia despite receiving 10 days of clindamycin therapy.","label":0,"label_text":"Not-Related"}
+{"text":"We present a 44-year-old female patient with generalised myasthenia gravis who developed progressive multifocal leukoencephalopathy.","label":0,"label_text":"Not-Related"}
+{"text":"Long-term lithium treatment attenuated the hypokinetic effect of reserpine in a patient with tardive dyskinesia.","label":0,"label_text":"Not-Related"}
+{"text":"Three cases with touch of an intact anterior vitreous face to the cornea following phacoemulsification had moderate corneal edema.","label":0,"label_text":"Not-Related"}
+{"text":"We postulate that in our patient, a subgaleal hemorrhage developed after vacuum delivery and possibly infected 11 months later, presumably from hematogenous seeding of an acute otitis media.","label":0,"label_text":"Not-Related"}
+{"text":"We present a case of photo-onycholysis in a patient treated with doxycycline for acne vulgaris.","label":1,"label_text":"Related"}
+{"text":"Refractory hypoglycemia from ciprofloxacin and glyburide interaction.","label":1,"label_text":"Related"}
+{"text":"Sexual dysfunction associated with intrathecal baclofen use: a report of two cases.","label":1,"label_text":"Related"}
+{"text":"The photosensitivity is still present 3 years after the withdrawal of quinine.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: This observation of \"on-off\" risperidone treatment suggests that risperidone may have worsened both psychiatric and physical manifestations of the mitochondrial disorder in this adolescent.","label":1,"label_text":"Related"}
+{"text":"After cessation of amantadine, the edema resolved, and the endothelial cell densities were <or=600\/mm.","label":1,"label_text":"Related"}
+{"text":"In rare patients, systemic absorption of inhaled tobramycin may be significant enough to produce toxic effects, such as renal and vestibular toxicities.","label":0,"label_text":"Not-Related"}
+{"text":"However, we have not identified previous reports suggesting interaction between MTX and COX-2 inhibitors.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of Zidovudine induced anaemia and bone marrow aplasia in a patient infected with HIV.","label":1,"label_text":"Related"}
+{"text":"The primary pathology was a spinal cord astrocytoma, grade II, with no intracranial extension.","label":0,"label_text":"Not-Related"}
+{"text":"Typical symptoms of active CD occurred 11, 12, and 26 months after start of etanercept therapy, respectively.","label":1,"label_text":"Related"}
+{"text":"Pregabalin is one of the newer drugs approved for the treatment of focal epilepsies.","label":0,"label_text":"Not-Related"}
+{"text":"A 40-year-old man with relapsing-remitting multiple sclerosis (MS) developed primary central nervous system lymphoma (PCNSL) after having received 21 doses of natalizumab monotherapy.","label":1,"label_text":"Related"}
+{"text":"We review the literature on previously reported cases of cutaneous necrosis after injection of standard interferon alfa or pegylated interferon alfa-2b and discuss the different pathophysiologic mechanisms that might be involved.","label":1,"label_text":"Related"}
+{"text":"We report a case of acne fulminans occurring during treatment with 13-cis-retinoic acid for cystic acne.","label":1,"label_text":"Related"}
+{"text":"This entity should be included in the differential diagnosis for renal transplant recipients with hypercalcemia, especially in patients who develop lung infections.","label":0,"label_text":"Not-Related"}
+{"text":"Carbamyl phosphate synthetase-1 deficiency discovered after valproic acid-induced coma.","label":1,"label_text":"Related"}
+{"text":"The ocular pressure of the second patient was 18.5 mmHg after a week, 21 mmHg after 2 weeks, and 23 mmHg after 16 days.","label":0,"label_text":"Not-Related"}
+{"text":"5-fluorouracil (5-FU)-associated peripheral neuropathy is an uncommon event.","label":1,"label_text":"Related"}
+{"text":"Occlusion of the right brachial and right femoral artery was ascertained by Doppler ultrasound.","label":0,"label_text":"Not-Related"}
+{"text":"It is derived from 6-mercaptopurine, and these two drugs are often used interchangeably.","label":0,"label_text":"Not-Related"}
+{"text":"This unusual psychopathology is probably encountered more by dermatologists than by mental health professionals.","label":0,"label_text":"Not-Related"}
+{"text":"Myocardial infarction is rare in pregnancy.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was treated by local excision and corticosteroids were decreased.","label":0,"label_text":"Not-Related"}
+{"text":"Aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension in a patient treated with trimethoprim-sulfamethoxazole.","label":1,"label_text":"Related"}
+{"text":"DATA SYNTHESIS: Genetic deficiencies in DPD, the rate-limiting enzyme responsible for 5-FU catabolism, may occur in 3% or more of patients with cancer putting them at increased risk for unusually severe adverse reactions (e.g., diarrhea, stomatitis, mucositis, myelosuppression, neurotoxicity) to standard doses of 5-FU.","label":1,"label_text":"Related"}
+{"text":"The Japanese literature was reviewed for reports on this allergy, and the occurrence due to budesonide was compared with that of other dermocorticosteroids.","label":0,"label_text":"Not-Related"}
+{"text":"This report describes an unexpected drug-induced hepatitis in a previously healthy young woman exposed to 2 doses of amodiaquine and artesunate.","label":1,"label_text":"Related"}
+{"text":"A dapsone hypersensitivity syndrome, consisting of fever, headache, nausea, vomiting, lymphadenopathy, hepatitis, hemolysis, leukopenia, and mononucleosis, has been described in patients treated with the drug for leprosy.","label":1,"label_text":"Related"}
+{"text":"Prolongation of the QT interval observed in a Japanese patient with vivax malaria following treatment with halofantrine.","label":1,"label_text":"Related"}
+{"text":"Within 3 weeks of beginning continuous daily isoniazid and rifampin therapy for pulmonary tuberculosis, a patient developed acute renal failure.","label":1,"label_text":"Related"}
+{"text":"Because of serious side effects of an increase in the QT interval causing torsades de pointes, dofetilide must be initiated with close monitoring of the QT interval in an inpatient setting.","label":1,"label_text":"Related"}
+{"text":"Data have been published regarding the possibility that tamoxifen may be responsible for the subsequent development of carcinoma of the corpus uteri in these patients.","label":1,"label_text":"Related"}
+{"text":"The diagnosis was made on the classical appearance of \"owl's eye\" inclusion bodies on colonic and hepatic biopsies and, in addition, viral serology and polymerase chain reaction (PCR) analysis of the cytomegalovirus DNA copy number.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Ten cases of blebitis and 33 cases of bleb-associated endophthalmitis were identified.","label":0,"label_text":"Not-Related"}
+{"text":"One of the cases reviewed went to jury trial and the record of that case is in the public domain.","label":0,"label_text":"Not-Related"}
+{"text":"There have also been two cases of patients with hepatitis C associated with focal segmental glomerulosclerosis.","label":0,"label_text":"Not-Related"}
+{"text":"New onset rapid cycling bipolar disorder is rare in late life.","label":0,"label_text":"Not-Related"}
+{"text":"The fibrinolytic state was achieved with a combination of intravenous and intraarterial infusions of urokinase.","label":0,"label_text":"Not-Related"}
+{"text":"A case of tuberculosis in a patient on Efalizumab and Etanercept for treatment of refractory palmopustular psoriasis and psoriatic arthritis.","label":1,"label_text":"Related"}
+{"text":"OBJECTIVE: To report 2 cases of serotonin syndrome with serious extrapyramidal movement disorders occurring when metoclopramide was coadministered with sertraline or venlafaxine.","label":1,"label_text":"Related"}
+{"text":"Possible mechanisms and preventive measures are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"A report of retinal artery occlusion associated with mitral valve prolapse and pregnancy is presented.","label":0,"label_text":"Not-Related"}
+{"text":"CASE: A nulliparous woman with a long history of intrauterine contraceptive device (IUD) and recent Papanicolaou smear findings consistent with the presence of actinomyces presented with chronic vague lower abdominal pain, weight loss, poor appetite, and recent increase in abdominal girth associated with a large immobile pelvic mass.","label":0,"label_text":"Not-Related"}
+{"text":"We present a case of disseminated cryptococcal infection in a patient with pemphigus vulgaris treated with high dose corticosteroids as monotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"The linear dimensions and SOMA scale were, respectively, 8 x 6 cm and 11 at 6 months; 4 x 4 cm and 7 at 12 months; and complete response with no measurable RIF and 1 at 18 months.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a characteristic speech disorder identified in a large series of consecutive patients undergoing OLT.","label":0,"label_text":"Not-Related"}
+{"text":"Laboratory abnormalities were initially attributed to chemotherapy toxicity.","label":0,"label_text":"Not-Related"}
+{"text":"Medications having adverse effects on potassium metabolism were considered, and the patient's use of timolol maleate eyedrops was discontinued.","label":0,"label_text":"Not-Related"}
+{"text":"Until more information is known about the safety of warfarin and azithromycin, caution is advised when the agents are given together.","label":0,"label_text":"Not-Related"}
+{"text":"Her mood improved significantly.","label":0,"label_text":"Not-Related"}
+{"text":"All-trans retinoic acid has recently been shown to induce differentiation of acute promyelocytic leukemia cells in vitro and in vivo.","label":0,"label_text":"Not-Related"}
+{"text":"A patient developed typical ECM after subcutaneous selfinjection of glatiramer acetate for multiple sclerosis.","label":1,"label_text":"Related"}
+{"text":"Two patients had ampicillin-associated seizures.","label":1,"label_text":"Related"}
+{"text":"Isoniazid causing breast tissue enlargement has been very rarely reported.","label":1,"label_text":"Related"}
+{"text":"Biopsy-proven acute interstitial nephritis associated with the tyrosine kinase inhibitor sunitinib: a class effect?","label":1,"label_text":"Related"}
+{"text":"Aspirin sensitivity: the role for aspirin challenge and desensitization in postmyocardial infarction patients.","label":0,"label_text":"Not-Related"}
+{"text":"Tuberculosis can involve multiple organ systems concurrently.","label":0,"label_text":"Not-Related"}
+{"text":"Scapular upward rotation is predominantly achieved via a force coupling involving the upper and lower trapezius and the serratus anterior.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: The present findings suggest that fluvoxamine can cause increased libido in some patients.","label":1,"label_text":"Related"}
+{"text":"Allergic contact dermatitis to compound tincture of benzoin.","label":1,"label_text":"Related"}
+{"text":"Ten patients received naloxone, 50% demonstrated clinical improvement in vital signs and CNS depression.","label":0,"label_text":"Not-Related"}
+{"text":"A coherent 84-year-old woman with occult CNV both eyes (OU) experienced decreased vision of 20\/800 OU.","label":0,"label_text":"Not-Related"}
+{"text":"The predominant feature was the abnormally increased formation of both 3 mono- and 4 double unsaturated metabolites of VPA amounting in plasma to 58%-71% of the sum of VPA plus all analyzed metabolites (controls maximal 15%) and in urine to 34%-61% (controls maximal 10%).","label":0,"label_text":"Not-Related"}
+{"text":"This case report describes a 13-year-old male with diagnosis of autistic disorder and fetishistic behavior.","label":0,"label_text":"Not-Related"}
+{"text":"Continuing the treatment with 13-cis-retinoic acid without systemic steroid eventually cleared the systemic manifestations and skin lesions.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: We report the case of a patient treated with capecitabine and radiation for rectal adenocarcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"These potentially life-threatening phenomena have led to treatment discontinuation and the consequent reemergence of psychiatric symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"DATA EXTRACTION: One author reviewed cases supplied by the other authors and abstracted information from published literature sources.","label":0,"label_text":"Not-Related"}
+{"text":"Forty-three of 101 outpatients with parkinsonism reported that they regularly experienced primary sensory symptoms, i.e., spontaneous abnormal sensations not caused by somatic disease.","label":0,"label_text":"Not-Related"}
+{"text":"The cases reported in the literature are all secondary to dental or periodontal disease.","label":0,"label_text":"Not-Related"}
+{"text":"Vitreous samples were obtained, followed by the injection of vancomycin 1 mg\/0.1 ml and ceftazidime 2.25 mg\/0.1 ml.","label":0,"label_text":"Not-Related"}
+{"text":"On day 7, blood obtained on day 4 was found to be strongly positive for HDAs.","label":0,"label_text":"Not-Related"}
+{"text":"We recommend that clinicians monitor patients for signs and symptoms of pancreatitis, including abdominal pain, during treatment with tigecycline.","label":1,"label_text":"Related"}
+{"text":"The former consisted of massive biventricular hypertrophy with chamber obliteration.","label":0,"label_text":"Not-Related"}
+{"text":"The edema disappeared with discontinuation of the drug regimen and did not reappear during a subsequent six-month observation period.","label":0,"label_text":"Not-Related"}
+{"text":"Because there were no other obvious causes of renal failure in either patient, we propose that skeletal muscle ischemia developed during vasopressin infusion, followed by release of myoglobin and renal damage.","label":1,"label_text":"Related"}
+{"text":"The patients received anticoagulation therapy and recovered completely.","label":0,"label_text":"Not-Related"}
+{"text":"Echocardiography revealed severe, global left-ventricular dysfunction.","label":0,"label_text":"Not-Related"}
+{"text":"Flap salvage is often successful if vascular complications are recognized and treated early.","label":0,"label_text":"Not-Related"}
+{"text":"Its ease of administration makes it an ideal drug to treat patients in the outpatient setting while maintaining adequate quality of life.","label":0,"label_text":"Not-Related"}
+{"text":"Multifocal osteonecrosis has a wide variety of etiologies, but is most often encountered in the clinical setting of corticosteroid administration, connective tissue disorders, transplantation, hemoglobinopathies and dysbarism.","label":0,"label_text":"Not-Related"}
+{"text":"In all the children with azotemia who were treated with aluminum hydroxide, there was a positive correlation (r = 0.90; P less than 0.01) between the serum aluminum level and the daily dose of elemental aluminum.","label":0,"label_text":"Not-Related"}
+{"text":"Methotrexate induced sprue-like syndrome.","label":1,"label_text":"Related"}
+{"text":"Severe diffuse interstitial pneumonitis induced by carmustine (BCNU).","label":1,"label_text":"Related"}
+{"text":"The hepatitis C infection was eradicated, but he continued to be diabetic requiring insulin therapy during the follow-up.","label":0,"label_text":"Not-Related"}
+{"text":"The second patient, who developed cholestasis after receiving trimethoprim-sulfamethoxazole, had marked duct paucity in the liver biopsy.","label":1,"label_text":"Related"}
+{"text":"A 22-year-old male, referred to us as a case of multi-drug resistant tuberculosis was diagnosed as allergic bronchopulmonary aspergillosis (ABPA) after serological and computed tomography confirmation.","label":0,"label_text":"Not-Related"}
+{"text":"We present a patient with human immunodeficiency virus infection under treatment with foscarnet for CMV retinitis who complained of thirst and polyuria.","label":1,"label_text":"Related"}
+{"text":"Posterior reversible encephalopathy syndrome is a treatable and reversible cause of acute encephalopathy with blindness, as long as an early diagnosis is made.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of severe anemia, which responded well to steroid therapy, in a patient receiving IL-2 plus IFN-alpha for metastatic renal cell carcinoma.","label":1,"label_text":"Related"}
+{"text":"We suggest that voriconazole may be a useful treatment alternative to the more traditional therapy with amphotericin B-based agents.","label":0,"label_text":"Not-Related"}
+{"text":"Implications for the neonate.","label":0,"label_text":"Not-Related"}
+{"text":"Bcr-Abl tyrosine kinase inhibitors (TKIs) such as imatinib or dasatinib produce high cytogenetic response rates in patients with Philadelphia-positive chronic myeloid leukaemia (CML) with a good overall safety profile.","label":0,"label_text":"Not-Related"}
+{"text":"A 27-year-old man with typical mitral leaflet prolapse syndrome was under medical care for eight years with ventricular arrhythmias resistant to various antiarrhythmic drugs.","label":0,"label_text":"Not-Related"}
+{"text":"Power spectrum analysis of heart rate variability is useful in this instance because it magnifies the trace and detects even minor disturbances.","label":0,"label_text":"Not-Related"}
+{"text":"She was subsequently rendered euthyroid with radioiodine treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Thus, the LNG-IUS is a viable option and represents a real advance in the treatment of adenomyosis.","label":0,"label_text":"Not-Related"}
+{"text":"The action of valproate in GABA metabolism and in GABA neuronal networks could produce a similar result through a hyperrecruitment of GABA-mediated postsynaptic transmission.","label":0,"label_text":"Not-Related"}
+{"text":"All had a history of chronic graft-vs-host disease (cGVHD) and all had active manifestations of cGVHD at MN diagnosis.","label":0,"label_text":"Not-Related"}
+{"text":"The daily VPA dose was increased to 1500 mg, and olanzapine was introduced.","label":0,"label_text":"Not-Related"}
+{"text":"Analgesic agents and a change from intravenous to oral administration of cyclosporine were ineffective in controlling the pain.","label":0,"label_text":"Not-Related"}
+{"text":"In conclusion, myalgias were due to focal RML produced probably by a combination of factors, particularly the chemotherapy along with dehydration due to gastrointestinal complications, infection, and the use of diverse antibiotics.","label":0,"label_text":"Not-Related"}
+{"text":"Although the mechanism of the pressure rise is unknown, all eyes in our series were controlled with medical therapy.","label":0,"label_text":"Not-Related"}
+{"text":"In keeping with findings in the literature, the aortic wall in this case was damaged by secondary changes following irradiation and Bleomycin treatment.","label":1,"label_text":"Related"}
+{"text":"Magnification revealed that these were scolices within cysticerci.","label":0,"label_text":"Not-Related"}
+{"text":"Her symptoms improved markedly, and follow-up arteriography 6 weeks later demonstrated resolution of the iliac dissections along with restoration of nearly normal lower extremity runoff vessels.","label":0,"label_text":"Not-Related"}
+{"text":"The patient recovered well, both cognitively and physically, and did not have any further symptoms in 1 year of follow-up.","label":0,"label_text":"Not-Related"}
+{"text":"However, to our knowledge, there are no accurate estimates of the incidence of CNV in other retinal vascular diseases, such as diabetic retinopathy.","label":0,"label_text":"Not-Related"}
+{"text":"This infection progressed despite treatment with antifungal regimens known to be effective, even in immunocompromised patients.","label":0,"label_text":"Not-Related"}
+{"text":"The mechanism of the decrease in plasma potassium induced by phosphate treatment was investigated in a 24-year-old hypertensive patient with hypophosphatemic osteomalacia, who was the youngest of four patients, belonging to a 23 number kindred of five generations.","label":1,"label_text":"Related"}
+{"text":"Reversible findings of restricted diffusion in 5-fluorouracil neurotoxicity.","label":1,"label_text":"Related"}
+{"text":"Side effects recurred with sequential dosage adjustments so that doses > 10 mg were not tolerated.","label":0,"label_text":"Not-Related"}
+{"text":"We have reviewed the literature on drug-induced ocular pemphigoid and have added our experience with five patients with glaucoma who developed ocular cicatricial (benign mucosal) pemphigoid after treatment with various topical glaucoma medications.","label":0,"label_text":"Not-Related"}
+{"text":"Three cases of head and neck PTLD treated at our institution are described.","label":0,"label_text":"Not-Related"}
+{"text":"Bone marrow aspiration and biopsy were diagnostic of pure red cell aplasia on a background hypocellular marrow.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Methotrexate (MTX) may induce liver damage, which in some psoriatics will lead to fibrosis or cirrhosis.","label":1,"label_text":"Related"}
+{"text":"It includes a description of the complication, how it occurred, was recognized, and corrected.","label":0,"label_text":"Not-Related"}
+{"text":"Sorafenib, a multitargeted kinase inhibitor used for the treatment of unresectable hepatocellular carcinoma and advanced renal cell carcinomas, received FDA approval in 2005.","label":0,"label_text":"Not-Related"}
+{"text":"Optic nerve sheath fenestration for a reversible optic neuropathy in radiation oncology.","label":0,"label_text":"Not-Related"}
+{"text":"They presented with circumscribed blue-grey pigmentation within acne scars confined to the back.","label":0,"label_text":"Not-Related"}
+{"text":"The importance of differentiation between primary and \"therapy-linked\" disease, and the difficulties in making such a distinction, are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"The patient used the recommended dose regularly, and he described progressive proximal muscle weakness and generalized myalgias, which started 1 month before presentation.","label":0,"label_text":"Not-Related"}
+{"text":"The prevalences of hypertension, coma\/unresponsiveness, seizures, and death were not as prominent in our study as previously reported, perhaps reflecting earlier recognition and intervention.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Some patients may thus have a spuriously low cell count and may be unnecessarily denied effective treatment.","label":0,"label_text":"Not-Related"}
+{"text":"The complexity of this situation can generate an impaired consciousness in the patients.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was ultimately treated with a combination of leflunomide and foscarnet.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Because blebitis may be prodromal to endophthalmitis, aggressive antimicrobial therapy, perhaps with oral quinolones, is warranted.","label":0,"label_text":"Not-Related"}
+{"text":"One had cutaneous anergy in vivo and profound reduction on mononuclear cell proliferative and interferon responses to tuberculoprotein (PPD) in vitro; the other patient, who died two weeks after starting treatment, had relatively normal values for these measures of cell-mediated immunity.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: In some abstainers who take cyanamide for several years, thin septum-like liver fibrosis progresses along with the emergence of ground-glass hepatocytes.","label":1,"label_text":"Related"}
+{"text":"Pamidronate therapy should be considered in patients with hypercalcemia secondary to acute vitamin D poisoning.","label":1,"label_text":"Related"}
+{"text":"Ischemic stroke associated with cough and cold preparation containing methylephedrine and supplement containing Chinese herbal drugs.","label":0,"label_text":"Not-Related"}
+{"text":"A 69-year-old female with chronic posterior uveitis was treated with cyclosporine while on concomitant oral simvastatin for hypercholesterolemia.","label":0,"label_text":"Not-Related"}
+{"text":"No re-occurrence of pancreatitis was observed in a 16 month follow-up.","label":0,"label_text":"Not-Related"}
+{"text":"After taking this treatment for 1 month, she presented with fever, diarrhea, localized edemas, generalized pruritic papular and erythematous rash and lymphadenopathies.","label":0,"label_text":"Not-Related"}
+{"text":"Evidence for zanamivir resistance in an immunocompromised child infected with influenza B virus.","label":0,"label_text":"Not-Related"}
+{"text":"Intraocular inflammation was minimal in all cases.","label":0,"label_text":"Not-Related"}
+{"text":"The patient continued to have fever and autonomic instability without evidence of infection which entirely resolved within 24 hours of reinstitution of full preadmission dosing of oral baclofen.","label":1,"label_text":"Related"}
+{"text":"We present a fatal case of subacute methanol toxicity with associated diffuse brain involvement, including bilateral putaminal necrosis and cerebral edema with ventricular compression.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: Sustained-release verapamil is thought to be the cause of the asthma attack in this patient because she was not taking any other preparations; the symptoms started with the administration of sustained-release verapamil and were relieved after its discontinuation.","label":1,"label_text":"Related"}
+{"text":"In one patient there was resolution of symptoms following cessation of ketamine, but some symptoms persisted until death in the other two.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: A 55-year-old woman became stuporous after overdose with lamotrigine (LTG) and valproic acid (VPA) tablets.","label":1,"label_text":"Related"}
+{"text":"In three patients Westergren sedimentation rate decreased for up to five months after exchanges.","label":0,"label_text":"Not-Related"}
+{"text":"Though a considerable number of such lesions are cutaneous in origin, melanoma has rarely been reported.","label":0,"label_text":"Not-Related"}
+{"text":"Studies with a plant fungicide, imazalil, with vapor-phase activity, in the therapy of human alternariosis.","label":0,"label_text":"Not-Related"}
+{"text":"Successful management was made possible by a new somatostatin analogue (Vapreotide), administered i.m. at weekly intervals.","label":0,"label_text":"Not-Related"}
+{"text":"A 66-year-old man with hepatic metastases from gastric adenocarcinoma was treated on two occasions with 5-fluoro-2-deoxyuridine (FUdR) via hepatic artery infusion (HAI).","label":0,"label_text":"Not-Related"}
+{"text":"Thus, the eosinophilia myalgia syndrome can be associated with parenteral tryptophan administration.","label":1,"label_text":"Related"}
+{"text":"NMS is a drug-related response to various medications, such as Haloperidol, which the patient was receiving.","label":1,"label_text":"Related"}
+{"text":"In this report we described a case of juvenile idiopathic arthritis patient who developed thymic enlargement (true thymic hyperplasia), mediastinal lymphadenopathy and pleurisy associated with systemic symptoms under Etanercept treatment.","label":1,"label_text":"Related"}
+{"text":"Cerebral manifestations of ergotism.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of severe respiratory failure due to gold salt toxicity in a patient suffering from rheumatoid arthritis requiring mechanical ventilation.","label":1,"label_text":"Related"}
+{"text":"Pulmonary edema occurred 24 hours after intravenous ritodrine therapy and 10 hours after subcutaneous terbutaline therapy.","label":1,"label_text":"Related"}
+{"text":"Diphenhydramine-induced wide complex dysrhythmia responds to treatment with sodium bicarbonate.","label":1,"label_text":"Related"}
+{"text":"Unusual weight fluctuation under corticosteroid and psychotropic treatment.","label":0,"label_text":"Not-Related"}
+{"text":"In this article, we describe another case of subcutaneous changes following repeated glatiramer acetate injection, presented as localized panniculitis in the area around the injection sites, in a 46-year-old female patient who was treated with glatiramer acetate for 18 months.","label":1,"label_text":"Related"}
+{"text":"For primary ventriculoperitoneal shunt insertion in infants and young children, the single-pass tunneling technique is safe and avoids one source of complications.","label":0,"label_text":"Not-Related"}
+{"text":"To our knowledge, this recurrence of amiodarone pulmonary toxicity has not been reported previously.","label":1,"label_text":"Related"}
+{"text":"Single drug level measurements may therefore be of little diagnostic value.","label":0,"label_text":"Not-Related"}
+{"text":"We describe children and adolescents with chronic hematologic and oncologic diseases who exhibited drug-seeking behavior or anticholinergic symptoms with the use of diphenhydramine.","label":1,"label_text":"Related"}
+{"text":"The technical images (abdominal CT, scintigraphic octreotide scan and renal arteriography) revealed the presence of a left adrenal pheochromocytoma and stenosis of the renal artery.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: Thirty-two patients with chronic hepatitis C were examined prospectively for changes in fundus findings while they were being treated with pegylated interferon and ribavirin.","label":0,"label_text":"Not-Related"}
+{"text":"He developed a cerebellar hemorrhage after repetitive pressing of the shunt reservoir.","label":0,"label_text":"Not-Related"}
+{"text":"There were gross functional lesions of the cardiovascular, renal, and neuromuscular systems with no structural abnormalities.","label":0,"label_text":"Not-Related"}
+{"text":"The coagulation disorders were treated with prothrombin complex concentrate 30 IU\/kg IV and vitamin K1 10 mg IV, and values normalized within 36 hours.","label":0,"label_text":"Not-Related"}
+{"text":"RESEARCH DESIGN AND METHODS: An in vitro exploration of cytokine production by peripheral blood mononuclear cells (PBMC) from the reported case was performed and compared with the same explorations of PBMC from three nondiabetic subjects and three diabetic patients without lipoatrophic lesions.","label":0,"label_text":"Not-Related"}
+{"text":"When pulmonary thromboembolism occurs, early diagnosis by pulmonary blood flow scintigram and early thrombolytic and anticoagulative therapies are necessary.","label":0,"label_text":"Not-Related"}
+{"text":"Use of haloperidol infusions to control delirium in critically ill adults.","label":0,"label_text":"Not-Related"}
+{"text":"This property is similar to that of other lipophilic agents such as amiodarone, chloroquine, chlorpromazine, quinacrine, and suramin.","label":0,"label_text":"Not-Related"}
+{"text":"Our case presents some of the challenges involved with managing ocular toxicity of these cardiac drugs.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Although mirtazapine offers clinicians a combination of strong efficacy and good safety, we suggest bearing SS in mind when prescribing this drug, especially in frail, elderly patients with underlying chronic conditions.","label":1,"label_text":"Related"}
+{"text":"DESIGN: Case report.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: The new quinolone derivatives (levofloxacin, sparfloxacin, grepafloxacin, trovafloxacin, gatifloxacin and moxifloxacin), also called gyrase inhibitors, are known for their potential to cause central nervous system-related adverse effects, including headache, dizziness and insomnia.","label":1,"label_text":"Related"}
+{"text":"A 56-year-old male who was 12 months status post liver transplant presented with a 2-month history of painful, erythematous nodules over the right knee.","label":0,"label_text":"Not-Related"}
+{"text":"We propose that patients being treated with curative intent receive full-dose intensity, using body surface area calculated on actual body weight or on ideal body weight with dose escalations if tolerated.","label":0,"label_text":"Not-Related"}
+{"text":"Acute coronary syndromes can be associated with the infusion of rituximab.","label":1,"label_text":"Related"}
+{"text":"Although bacterial keratitis occurs rarely after refractive surgery, patients should be informed of the potential risk for visual loss caused by this infection.","label":0,"label_text":"Not-Related"}
+{"text":"Despite therapeutic drug monitoring and subsequent efavirenz dosage reductions, side-effects did not resolve completely and lopinavir concentrations remained relatively low.","label":0,"label_text":"Not-Related"}
+{"text":"A 22-year-old man presented with hematuria and was found to have a mass in his urinary bladder on computed tomography.","label":0,"label_text":"Not-Related"}
+{"text":"We present a case of the syndrome of inappropriate antidiuretic hormone (SIADH) secondary to cisplatin therapy in a patient with advanced-stage large cell neuroendocrine carcinoma of the cervix.","label":1,"label_text":"Related"}
+{"text":"He was treated sequentially with prednisone and azathioprine (2 weeks), decreasing doses of prednisone alone (21 months), and no immunosuppressive drugs (10 months).","label":0,"label_text":"Not-Related"}
+{"text":"After admission, she received oral calcium polystyrene sulfonate and sorbitol to treat hyperkalemia.","label":0,"label_text":"Not-Related"}
+{"text":"He has remained asymptomatic.","label":0,"label_text":"Not-Related"}
+{"text":"Our findings suggest that significant progression of marrow reticulin fibrosis during imatinib therapy can be an indicator for a return or progression of CML and, in some patients with CML, imatinib may promote cytogenetic clonal evolution, resulting in a poor response to treatment.","label":1,"label_text":"Related"}
+{"text":"This reaction is better known with carbamazepine and phenytoin, but is less common with broad-spectrum antiepileptic drugs such as valproic acid.","label":0,"label_text":"Not-Related"}
+{"text":"The patient did experience nasal mucosal friability and diffuse hyperpigmentation of the face and hands.","label":0,"label_text":"Not-Related"}
+{"text":"The pseudolymphoma syndrome is a reversible reactive condition consisting of fever, lymphadenopathy and generalized rash.","label":0,"label_text":"Not-Related"}
+{"text":"The patient developed severe hepatitis after chemotherapy and, despite achieving complete remission of the malignancy, died of hepatic failure.","label":0,"label_text":"Not-Related"}
+{"text":"To rule out fibrin sheath formation, catheter dye studies need to be obtained when fibrinolytic therapy has failed to restore catheter function.","label":0,"label_text":"Not-Related"}
+{"text":"Acute pancreatitis was confirmed surgically.","label":0,"label_text":"Not-Related"}
+{"text":"Electron microscopic examination of the heart revealed changes characteristic of adriamycin cardiomyopathy.","label":0,"label_text":"Not-Related"}
+{"text":"We report the 1st case of R. equi brain abscess in a patient receiving corticosteroid monotherapy and review the literature for risk factors and sites of infection.","label":0,"label_text":"Not-Related"}
+{"text":"A case of intravenous catheter-related cutaneous aspergillosis and Aspergillus fumigatus fungemia in an HIV-positive patient with Burkitt-cell acute lymphocytic leukemia is reported.","label":0,"label_text":"Not-Related"}
+{"text":"Retinopathy in hepatitis C patients due to combination therapy with pegylated interferon and ribavirin.","label":1,"label_text":"Related"}
+{"text":"PFGE revealed different patterns of banding, excluding that interpatient contamination occured.","label":0,"label_text":"Not-Related"}
+{"text":"Other mechanisms have been postulated by other investigators.","label":0,"label_text":"Not-Related"}
+{"text":"A challenge with clozapine was feasible and showed no clinical symptoms of eosinophilia.","label":0,"label_text":"Not-Related"}
+{"text":"The authors present a case report of a granulomatous reaction leading to urethral prolapse, 3 months after the transurethral injection of calcium hydroxylapatite.","label":1,"label_text":"Related"}
+{"text":"Ketanserin in the treatment of protamine-induced pulmonary hypertension.","label":1,"label_text":"Related"}
+{"text":"The majority of patients, however, do not require the use of steroids.","label":0,"label_text":"Not-Related"}
+{"text":"Sedation in the morning was identified as an important adverse event, which should be addressed by reducing the dose.","label":0,"label_text":"Not-Related"}
+{"text":"Upon admission, all home medications, including pantoprazole, were reinitiated based on the patient's medication list.","label":0,"label_text":"Not-Related"}
+{"text":"This report describes the first case of insulin-induced cardiac failure in a patient without underlying heart disease.","label":1,"label_text":"Related"}
+{"text":"Physicians who now routinely treat RLS patients with dopaminergic agents should be aware of this abuse potential.","label":0,"label_text":"Not-Related"}
+{"text":"In this event the occurrence of neurotoxicity does not correlate with serum lithium levels.","label":0,"label_text":"Not-Related"}
+{"text":"A 35-year-old man with seropositive rheumatoid arthritis developed selective IgA deficiency during treatment with fenclofenac.","label":1,"label_text":"Related"}
+{"text":"It should therefore be instituted in good time in potentially life-threatening cases of intoxication.","label":0,"label_text":"Not-Related"}
+{"text":"Early signs of toxicity in the 2 survivors were peripheral neuropathy (day 4), bone marrow toxicity (day 5), gastrointestinal toxicity (days 6 and 7), and hypertension (days 7 and 8).","label":0,"label_text":"Not-Related"}
+{"text":"We report on a patient who underwent renal transplantation using Campath-1H induction and tacrolimus maintenance therapy who developed HUS, which was managed by plasma exchange and switch to Rapamycin.","label":0,"label_text":"Not-Related"}
+{"text":"We report a patient of organic bipolar affective disorder who developed hiccups with the atypical antipsychotic aripiprazole.","label":1,"label_text":"Related"}
+{"text":"A case is presented in which a 68-year-old man became delirious after being withdrawn from a low dosage of alprazolam.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: Topical tacrolimus 0.03% ointment seems to be a promising second-line immunosuppressant in management of high-risk grafts.","label":0,"label_text":"Not-Related"}
+{"text":"All patients presented with sudden, very marked decrease in vision, with little or no pain, tenderness, conjunctival redness, or discharge.","label":0,"label_text":"Not-Related"}
+{"text":"Also, there are some suggestions of an underlying susceptibility and possibly a genetic predisposition, at least in some patients.","label":0,"label_text":"Not-Related"}
+{"text":"The polycystic changes disappeared from the ovaries in 2 of the women after valproate therapy was discontinued, and the 2 women who had gained weight and developed amenorrhea while being treated with valproate lost weight and resumed menstruating after the change in medication.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND AND OBJECTIVES: Penile erections following the initiation of either axial regional or general anesthesia is rare; however, when it occurs in patients undergoing urologic procedures it may delay, or even cancel, the planned surgery.","label":0,"label_text":"Not-Related"}
+{"text":"We hypothesized that vigorous rubbing of the eye of the atopic patient might cause limbal erosion that could lead to exposure of the angle-supported AC IOL haptic through the limbus.","label":0,"label_text":"Not-Related"}
+{"text":"Normeperidine is eliminated by the kidneys and accumulates in patients with renal insufficiency, sickle cell disease, and cancer.","label":0,"label_text":"Not-Related"}
+{"text":"A 33-year-old man with a history of recreational benztropine abuse presented to the emergency department with confusion, abdominal pain, and distention.","label":1,"label_text":"Related"}
+{"text":"CLL and AML\/MDS were diagnosed concurrently in two patients.","label":0,"label_text":"Not-Related"}
+{"text":"Biopsy of the skin rash demonstrated superficial perivascular lymphocytic infiltrate and was consistent with a drug reaction.","label":0,"label_text":"Not-Related"}
+{"text":"Accidental intra-arterial injection of drugs is a sporadic complication in i.v. drug addicts.","label":0,"label_text":"Not-Related"}
+{"text":"Despite a postulated dopaminergic mechanism, there seems to have been only one previous report of amantadine's precipitating psychosis in a schizophrenic patient.","label":1,"label_text":"Related"}
+{"text":"The changes in trace metals after DFO treatment were not consistent.","label":0,"label_text":"Not-Related"}
+{"text":"Temporary neurologic abnormalities were observed in one out of 23 patients undergoing chemotherapy with high-dose methotrexate (HD-MTX) for osteogenic sarcoma.","label":1,"label_text":"Related"}
+{"text":"Cardiac disease is a significant complication of childhood oncologic therapy.","label":0,"label_text":"Not-Related"}
+{"text":"PURPOSE: The occurrence of myoclonus associated with continuous i.v. infusion of dobutamine in a patient with end-stage renal disease (ESRD) is described.","label":1,"label_text":"Related"}
+{"text":"We describe a patient who developed granulocytopenia and fever after taking dipyrone and discuss the available literature.","label":1,"label_text":"Related"}
+{"text":"Charcoal hemoperfusion and sequential dialysis were performed because of the serious risk of fatality following such a massive dose of dapsone.","label":0,"label_text":"Not-Related"}
+{"text":"Because the primary reservoir of S. agalactiae in the human body is the gastrointestinal tract, and because no findings suggested an alternate portal of entry in our male donor, a gastrointestinal source was suspected.","label":0,"label_text":"Not-Related"}
+{"text":"Laboratory tests revealed elevated serum creatine kinase, aspartate aminotransferase, alanine aminotransferase, and lactate dehydrogenase.","label":0,"label_text":"Not-Related"}
+{"text":"Protease inhibitors (ritonavir and saquinavir) were added to the treatment and the patient developed progressive ataxia related to carbamazepine toxicity.","label":1,"label_text":"Related"}
+{"text":"Salmonella meningitis and multiple cerebral abscesses in an infant.","label":0,"label_text":"Not-Related"}
+{"text":"We suggest that patients receiving a high dose of vinblastine are at risk for the development of this syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"NMS must be considered as part of the differential diagnosis of fever in burn patients receiving medication known to cause the syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Here we report a patient with newly diagnosed acute promyelocytic leukemia who developed acute focal myositis, synovitis, and possible vasculitis, after receiving all-trans retinoic acid therapy.","label":1,"label_text":"Related"}
+{"text":"After a total of more than 500 cardioversions, all antiarrhythmic medications were withdrawn, and the nonselective beta-blocker propranolol was initiated.","label":0,"label_text":"Not-Related"}
+{"text":"Onychomycosis. New therapies for an old disease.","label":0,"label_text":"Not-Related"}
+{"text":"Graves' hyperthyroidism following transient thyrotoxicosis during interferon therapy for chronic hepatitis type C.","label":1,"label_text":"Related"}
+{"text":"Nutritional support via enteral feeding tubes may interfere with the response to medications by a number of mechanisms.","label":0,"label_text":"Not-Related"}
+{"text":"This mode of therapy was effective in treating severe gingival hyperplasia in a patient receiving systemic androgen therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Pulmonary hemorrhage is an uncommon feature in the HUS, and seems to appear especially in the HUS associated with MMC therapy.","label":1,"label_text":"Related"}
+{"text":"This observation might suggest caution when cisplatin is used in patients with cardiac disease or pretreated with other potential cardiotoxic antineoplastic agents.","label":0,"label_text":"Not-Related"}
+{"text":"We noted C. striatum to be the infecting pathogen or copathogen in six patients.","label":0,"label_text":"Not-Related"}
+{"text":"Linear IgA bullous dermatosis responsive to a gluten-free diet.","label":0,"label_text":"Not-Related"}
+{"text":"A 33-year-old woman visited our dermatologic clinic complaining of frequent oral ulceration for 10 years and generalized discoloration of her skin for 5 years.","label":0,"label_text":"Not-Related"}
+{"text":"One of three stool samples was positive for the presence of occult blood.","label":0,"label_text":"Not-Related"}
+{"text":"There have been only two reports of cimetidine-induced hepatitis.","label":1,"label_text":"Related"}
+{"text":"We propose a common mechanism: the vasoconstrictors caused systemic hypertension, increased left ventricular afterload, decreased left ventricular compliance, and decreased cardiac output.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a 57-year-old man with acral erythrocyanosis progressing to acute digital ischemia and gangrene that developed after combined chemotherapy (bleomycin and methotrexate) used to treat a metastatic squamous cell carcinoma of the hypopharynx.","label":1,"label_text":"Related"}
+{"text":"The site of thrombosis and the chronological relationship with the IIR implicates a hypersensitivity to infliximab in the causation of the venous thrombosis in this case.","label":1,"label_text":"Related"}
+{"text":"The role of GP IIb\/IIIa inhibitors in patients with NSTE ACS and elevated troponin levels who are undergoing PCI has been well established, even for patients receiving high-dose clopidogrel.","label":0,"label_text":"Not-Related"}
+{"text":"CASE SUMMARY: A 46-year-old African-American man experienced recurrent grand mal seizures during intravenous infusion of amphotericin B, then petit mal seizures as the infusion was stopped and the drug concentrations decreased with time.","label":1,"label_text":"Related"}
+{"text":"Recurrent hepatitis C and CSD were ultimately managed by the application of pegylated interferon.","label":0,"label_text":"Not-Related"}
+{"text":"Infliximab therapy in pediatric Crohn's pouchitis.","label":0,"label_text":"Not-Related"}
+{"text":"A 16-year-old boy developed fever, generalized rigidity, leukocytosis, and increased serum transaminase and creatine kinase levels while receiving treatment with olanzapine and lithium.","label":1,"label_text":"Related"}
+{"text":"DIAGNOSIS: Sustained ventricular tachycardia possibly owing to thalidomide treatment.","label":1,"label_text":"Related"}
+{"text":"Zidovudine use in pregnancy: a report on 104 cases and the occurrence of birth defects.","label":1,"label_text":"Related"}
+{"text":"No regional side effects were noted.","label":0,"label_text":"Not-Related"}
+{"text":"Patients with RA received intradermal (id) injections of di-Lex incorporated in liposome or of high molecular weight glycoprotein, or tumor associated carbohydrate antigen (TCA), containing the same carbohydrate epitope as di-Lex.","label":0,"label_text":"Not-Related"}
+{"text":"We report on a patient with thrombosis of a prosthetic mitral valve who developed severe embolic complications following the administration of the thrombolytic agent.","label":0,"label_text":"Not-Related"}
+{"text":"This is a case report of subtle, mild hypothermia in a 54-year old female patient receiving risperidone for schizophrenia.","label":1,"label_text":"Related"}
+{"text":"The serum immunoglobulin level returned to the normal range after the prednisolone was tapered off.","label":0,"label_text":"Not-Related"}
+{"text":"We evaluated drug-specific T cell responses in a patient with refractory partial seizures and paroxysmal kinesigenic choreoathetosis successfully treated with clinical desensitization to phenytoin.","label":0,"label_text":"Not-Related"}
+{"text":"We report here the first case using posaconazole for treatment of trichosporonosis in a liver transplant recipient caused by T. mucoides.","label":0,"label_text":"Not-Related"}
+{"text":"L-asparaginase-induced pancreatitis is an uncommon but potential lethal complication of the treatment of leukemia.","label":1,"label_text":"Related"}
+{"text":"Antibiotic lock technique.","label":0,"label_text":"Not-Related"}
+{"text":"Mr. C. was less tired and had more energy following his first and subsequent courses of therapy.","label":0,"label_text":"Not-Related"}
+{"text":"A recheck of blood chemistries confirmed hyponatremia.","label":0,"label_text":"Not-Related"}
+{"text":"Myoglobinuria and acute renal failure were observed in two patients with vasopressin-treated gastrointestinal hemorrhage.","label":1,"label_text":"Related"}
+{"text":"Under the suspicion of amiodarone-induced acute pancreatitis, amiodarone was substituted by propafenone.","label":1,"label_text":"Related"}
+{"text":"The subsequent reabsorption of free water from the fluid collection, with the contribution of postoperative hypotonic intravenous fluid administration and possible transient inappropriate antidiuretic hormone (ADH) secretion resulted in acute dilutional hyponatremia and consequent seizures.","label":0,"label_text":"Not-Related"}
+{"text":"Lidocaine (a sodium channel blocker) serves as an antiepilepsy drug in neonates.","label":0,"label_text":"Not-Related"}
+{"text":"After the initial pairings, the taste alone was offered between CY treatments.","label":0,"label_text":"Not-Related"}
+{"text":"The immunopathogenesis remains obscure, but is suggestive of an antigen-specific process requiring the presence of or exposure to ibuprofen.","label":0,"label_text":"Not-Related"}
+{"text":"A 31-year-old female developed multiple episodes of grand mal seizures after combination chemotherapy with cisplatin, vinblastine and bleomycin for germ cell ovarian cancer stage Ic.","label":1,"label_text":"Related"}
+{"text":"Folinic acid, the 5-formyl derivative of tetrahydrofolic acid, is the active form of folic acid.","label":0,"label_text":"Not-Related"}
+{"text":"Subfascial hematoma remains a rare and self-limited complication of thrombolytic therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Crohn's disease has not been associated with its administration.","label":0,"label_text":"Not-Related"}
+{"text":"Cholelithiasis and thrombosis of the central retinal vein in a renal transplant recipient treated with cyclosporin.","label":1,"label_text":"Related"}
+{"text":"Complete remission was observed after 6 to 10 weeks of imiquimod 5% (10 mg\/cm of skin cancer) treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Eleven were seropositive and 2 had Felty's syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Our experience supports hemodialysis for ESRF patients with atenolol toxicity.","label":1,"label_text":"Related"}
+{"text":"A 70-year-old homebound patient was experiencing new onset porthostatic hypotension and lightheadedness.","label":0,"label_text":"Not-Related"}
+{"text":"Due to the absence of other contributing factors and the temporal relationship between tolterodine and prolonged INR, the event was determined to be a probable drug interaction.","label":0,"label_text":"Not-Related"}
+{"text":"During PUVA treatment a 66-year-old woman with mycosis fungoides in stage III suddenly developed widespread papulonodular lesions of alarming clinical and histological appearance.","label":0,"label_text":"Not-Related"}
+{"text":"Ninety-two microg kg-1 were given thereafter at time intervals of 2 h until 12 h, then every 3 h until 24 h, and every 4 h until 48 h after surgery.","label":0,"label_text":"Not-Related"}
+{"text":"Following this incident, the patient was seen weekly and treated with conjugated vaginal oestrogen cream.","label":0,"label_text":"Not-Related"}
+{"text":"MDS was diagnosed 8.4 months after beginning TMZ.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients treated with 5-fluorouracil (5-FU) for disseminated adenocarcinoma of the colon developed cerebellar dysfunction typical of 5-FU neurotoxicity.","label":1,"label_text":"Related"}
+{"text":"Currently, a national randomized trial by the National Prostatic Cancer Project is evaluating this therapeutic innovation.","label":0,"label_text":"Not-Related"}
+{"text":"Intravenous verapamil therapy in babies may cause apnea, hypotension, and bradycardia; continued episodes of atrial flutter in a child may cause sudden death; quinidine may be related to the death; children with \"familial seizure disorders\" may in fact have the long QT interval syndrome.","label":1,"label_text":"Related"}
+{"text":"Treatment included induction chemotherapy in preparation for a bone marrow transplant, which resulted in the disappearance of the cutaneous lesions.","label":0,"label_text":"Not-Related"}
+{"text":"The eighth exhibited concentric constriction.","label":0,"label_text":"Not-Related"}
+{"text":"No abnormalities were identified on review of collection and processing records.","label":0,"label_text":"Not-Related"}
+{"text":"The drug was administered by continuous subcutaneous or intravenous infusions using a light weight portable constant infusion device.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Pelvic actinomycosis is a chronic suppurative inflammatory disease caused by the anaerobic Gram-positive bacilli Actinomyces israelii.","label":0,"label_text":"Not-Related"}
+{"text":"While on a maximal dose of phenylephrine she developed prominent positive U waves, which disappeared with the cessation of the drug.","label":1,"label_text":"Related"}
+{"text":"A cerebrospinal fluid examination meningitis.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Amphotericin B seems to be the probable cause of the seizures.","label":1,"label_text":"Related"}
+{"text":"Pulmonary nodules in osteosarcoma patients: differential diagnosis of central venous catheter-related infections in the lungs.","label":0,"label_text":"Not-Related"}
+{"text":"Discontinuation of the drug appeared to be responsible for the resolution of symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"Levamisole was administered for 5 weeks (total dose, 1,500 mg).","label":0,"label_text":"Not-Related"}
+{"text":"We report on a patient with acromegaly who developed severe drug-induced hepatitis during combined treatment with the long-acting somatostatin-analog octreotide and the GH receptor antagonist pegvisomant.","label":1,"label_text":"Related"}
+{"text":"Spinal cord compression induced by steroid therapy: CT findings.","label":0,"label_text":"Not-Related"}
+{"text":"RT-PCR and genomic PCR methodologies were used to identify a G to A mutation in the GT 5' splicing recognition sequence of intron 14, resulting in a 165-bp deletion (corresponding to exon 14) in this patient's DPD mRNA.","label":0,"label_text":"Not-Related"}
+{"text":"On the next day, after a total dose of only 600 mg of danazol, gingival bleeding and purpura occurred.","label":1,"label_text":"Related"}
+{"text":"Awareness of this disease and need for prompt institution of therapy is stressed.","label":0,"label_text":"Not-Related"}
+{"text":"No severe side effects occurred, except for slight pain in the nodules after infusion and an urticarial reaction at the tumor sites.","label":0,"label_text":"Not-Related"}
+{"text":"Alopecia, nausea, and vomiting were attributed to the cyclophosphamide component of the therapy.","label":1,"label_text":"Related"}
+{"text":"Liver biopsy disclosed submassive hepatic necrosis.","label":0,"label_text":"Not-Related"}
+{"text":"A patient with Parkinson's disease, initially treated with bromocriptine and subsequently with cabergoline, developed progressive pleuropulmonary abnormalities during the latter therapy.","label":1,"label_text":"Related"}
+{"text":"Disodium cromoglycate inhibited both responses.","label":0,"label_text":"Not-Related"}
+{"text":"An association of granulocytopenia, eosinophilia, skin reaction and hepatitis during propylthiouracil (PTU) therapy for thyrotoxicosis in a 47 year old black female is reported.","label":1,"label_text":"Related"}
+{"text":"Iron was absent.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Our report describes a case of rhabdomyolysis possibly caused by C. mukul and underlines the need for active surveillance of natural products.","label":0,"label_text":"Not-Related"}
+{"text":"Percutaneous transseptal mitral valvuloplasty was attempted in a patient with severe rheumatic mitral stenosis.","label":0,"label_text":"Not-Related"}
+{"text":"Five patients took a combination of herbs and presented with jaundice, fatigue and pruritus.","label":0,"label_text":"Not-Related"}
+{"text":"Combined occlusion of the central retinal artery and central retinal vein is an infrequently encountered clinical entity.","label":0,"label_text":"Not-Related"}
+{"text":"Presumed reactivation of herpes zoster ophthalmicus following laser in situ keratomileusis.","label":0,"label_text":"Not-Related"}
+{"text":"No relationship between amisulpride and rhabdomyolysis was found.","label":0,"label_text":"Not-Related"}
+{"text":"The authors presented a case of pulmonary hypertension during lithium therapy, while she has been on lithium for 6 years.","label":1,"label_text":"Related"}
+{"text":"Vitamin K2 was infused along with discontinuation of warfarin.","label":0,"label_text":"Not-Related"}
+{"text":"This isolate was lost in storage and could not be characterized further.","label":0,"label_text":"Not-Related"}
+{"text":"Propoxyphene-induced wide QRS complex dysrhythmia responsive to sodium bicarbonate--a case report.","label":1,"label_text":"Related"}
+{"text":"Following a closed mitral valvotomy, she received quinidine, 1.2 g\/day, without interruption for 17 years.","label":0,"label_text":"Not-Related"}
+{"text":"Drug withdrawal and brief steroid therapy resulted in clinical remission within two months of diagnosis.","label":0,"label_text":"Not-Related"}
+{"text":"Along with normal results of a hepatorenal panel and normal serum vitamin B12 and folate levels, no metabolic or endocrinologic alterations were present to explain the nail pigmentation and dystrophic changes.","label":0,"label_text":"Not-Related"}
+{"text":"Hepatolithiasis (intrahepatic stone) during octreotide therapy for acromegaly: a case report.","label":1,"label_text":"Related"}
+{"text":"A prolonged, complete disappearance of B-cells from the peripheral blood was observed.","label":0,"label_text":"Not-Related"}
+{"text":"Since August, 1989, the primary immunosuppressive agent is FK-506 (Tacrolimus).","label":0,"label_text":"Not-Related"}
+{"text":"Cholesterol embolization (CE) is a potentially serious complication associated with invasive arterial maneuvers, in which standard therapy has not been established.","label":0,"label_text":"Not-Related"}
+{"text":"It has relatively weak effects on norepinephrine and serotonin reuptake but possesses significant dopamine agonist and reuptake blocking effects.","label":0,"label_text":"Not-Related"}
+{"text":"A brief review of organophosphate poisoning and the unique features of our case are presented.","label":0,"label_text":"Not-Related"}
+{"text":"The harlequin color change is an unusual cutaneous phenomenon observed in newborn infants as transient, benign episodes of a sharply demarcated erythema on half of the infant, with simultaneous contralateral blanching.","label":0,"label_text":"Not-Related"}
+{"text":"Flutamide withdrawal syndrome is characterized by a decrease in prostate-specific antigen (PSA) after flutamide withdrawal in a subset of patients with progressing metastatic carcinoma of the prostate.","label":1,"label_text":"Related"}
+{"text":"We present the first report of N. exalbida brain abscess in a 63-year-old male patient with follicular lymphoma.","label":0,"label_text":"Not-Related"}
+{"text":"Chlorambucil central nervous toxicity: a significant side effect of chlorambucil therapy in childhood nephrotic syndrome.","label":1,"label_text":"Related"}
+{"text":"Rapidly developing hyperglycemia during treatment with olanzapine.","label":1,"label_text":"Related"}
+{"text":"Chest radiograph revealed diffuse bilateral infiltrates.","label":0,"label_text":"Not-Related"}
+{"text":"Fibrin sheath formation and chemotherapy extravasation: a case report.","label":0,"label_text":"Not-Related"}
+{"text":"She remained asymptomatic during the therapeutic period and the pulmonary nodules resolved six months later.","label":0,"label_text":"Not-Related"}
+{"text":"On day 7 of linezolid treatment, the patient developed severe pruritus, macular rash, facial edema, eosinophilia, marked increase in serum creatinine level, and mild hepatitis.","label":1,"label_text":"Related"}
+{"text":"Traditional topical measures to reduce local tissue damage, including corticosteroids, sodium bicarbonate, and ice applications, have not consistently demonstrated beneficial effects.","label":0,"label_text":"Not-Related"}
+{"text":"Malpractice litigation was brought about because the patient alleged that he had steroid cataracts, which resulted from his having received systemic corticosteroids.","label":0,"label_text":"Not-Related"}
+{"text":"Ultrastructurally, the discrete osmiophilic immune complexes were epimembranous.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: The patient required insulin desensitization for severe urticaria, angioedema, and occasional wheezing resulting from her insulin dose.","label":1,"label_text":"Related"}
+{"text":"The procedure was carried out without fluoroscopic control and was complicated by a puncture of the thecal sack.","label":0,"label_text":"Not-Related"}
+{"text":"Abdominal sonography and brain CT scan were normal.","label":0,"label_text":"Not-Related"}
+{"text":"If renin is low and plasma aldosterone fails to be suppressed by saline infusion, a trial of dexamethasone would seem indicated before other investigations are carried out.","label":0,"label_text":"Not-Related"}
+{"text":"This illustrates a rare case of gastrointestinal adverse reaction to pancreatic enzymes that was treated successfully with desensitization.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients with surgically implanted right atrial silastic catheters for home hyperalimentation developed central vein septic thrombophlebitis.","label":0,"label_text":"Not-Related"}
+{"text":"Only after three subsequent episodes of severe, symptomatic thrombocytopenia over the next four weeks did he say, upon repeat questioning, that he had continued to take quinine for night leg cramps.","label":1,"label_text":"Related"}
+{"text":"Further investigation revealed hyponatremia 112 mEq\/L, low serum osmolality, high urine osmolality, normal renal function, normal adrenal and thyroid hormones, and high plasma vasopressin 40 pg\/mL.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: A total of 176 burnt eyes of 98 patients suffering from severe eye burns were retrospectively reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"The cancer developed on a very thin endometrium and transvaginal ultrasonography failed to detect it.","label":0,"label_text":"Not-Related"}
+{"text":"We report a child with yolk sac tumor who developed localized pigmentation after the first course of chemotherapy regimen that included cisplatin, etoposide and bleomycin.","label":1,"label_text":"Related"}
+{"text":"Various etiologic factors have been implicated in PVOD after BMT.","label":0,"label_text":"Not-Related"}
+{"text":"We present the first case of ovarian endometrioid carcinoma and endometriosis in a postmenopausal patient who was treated with tamoxifen for breast cancer.","label":1,"label_text":"Related"}
+{"text":"We reviewed the literature on the effects of corticosteroids and chemotherapy on aaa formation and discuss possible mechanisms for drug action to promote aneurysm expansion and rupture.","label":0,"label_text":"Not-Related"}
+{"text":"In such patients, desensitization may enable the patient to continue treatment with methotrexate.","label":0,"label_text":"Not-Related"}
+{"text":"In our experience and in other limited published data, adverse effects are rare, but prolongation of the QT interval has occurred and multiform ventricular tachycardia is likely a risk.","label":0,"label_text":"Not-Related"}
+{"text":"Can roxithromycin and betamethasone induce acute pancreatitis? A case report.","label":1,"label_text":"Related"}
+{"text":"We reviewed the literature pertaining the management of pelvic actinomycosis.","label":0,"label_text":"Not-Related"}
+{"text":"Recognition of this rare entity will help clinicians avoid aggressive investigative and treatment modalities that can affect the results of PRK.","label":0,"label_text":"Not-Related"}
+{"text":"A 44-year-old woman is described in whom amiodarone, disopyramide, and quinidine, administered alone separately, induced atypical ventricular tachycardia (AVT, torsade de pointes).","label":1,"label_text":"Related"}
+{"text":"While approximately 70% of patients with schizophrenia and other psychotic disorders show a clear-cut reduction of symptoms in clinical trials, there is considerable variation in individual patient outcome, ranging from complete remission to absolute refractoriness.","label":0,"label_text":"Not-Related"}
+{"text":"Previous studies have demonstrated the interaction of MTX and a variety of non-steroidal, anti-inflammatory drugs (NSAIDs) with various clinical manifestations including acute renal failure, pancytopenia, vomiting, diarrhea, elevated liver transaminases, jaundice, mucosal ulcerations, and pyrexia.","label":1,"label_text":"Related"}
+{"text":"The five human eyes of three patients have shown no evidence of intraocular toxicity with a median follow-up time of 3.6 months (range 2.0-6.4 months).","label":0,"label_text":"Not-Related"}
+{"text":"The patient was treated with a combination of vibramycin and rifampicin for 5 months.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of a 45-year-old man who had disseminated blastomycosis that involved the lungs, skin, and ocular uvea and who was successfully treated with systemic and local antifungal therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Case study: adverse response to clonidine.","label":1,"label_text":"Related"}
+{"text":"Moreover, the perforation occurred despite using a minimum concentration of the drug, risk factors were absent, and the surgery was performed by an experienced surgeon.","label":0,"label_text":"Not-Related"}
+{"text":"The latter was discontinued slowly over a period of 10 weeks.","label":0,"label_text":"Not-Related"}
+{"text":"A few recent individual case reports have suggested that a myasthenic syndrome may be associated with statin treatment, but this association is not well described.","label":1,"label_text":"Related"}
+{"text":"We report a case of 48-year-old woman with seizure disorder on divalproex sodium (Depakote) who presented with dyspnea.","label":1,"label_text":"Related"}
+{"text":"2-Chlordeoxyadenosine (2-CdA) is an antineoplastic\/immunosuppressive agent used to treat hairy cell leukemia (HCL), chronic lymphocytic leukemia, and low-grade lymphomas.","label":0,"label_text":"Not-Related"}
+{"text":"Examinations 1 1\/2 to 7 1\/2 years after therapy revealed all of the patients to be within normal range for height and weight, but 3 of the 6 patients treated for 8 months or longer were in the lower range of normal.","label":0,"label_text":"Not-Related"}
+{"text":"We describe seven cases of retinal pigment epithelial (RPE) tear, which developed in seven eyes of seven patients following PDT.","label":0,"label_text":"Not-Related"}
+{"text":"The route of transmission may have been direct contamination of the connection device or bacterial translocation through the gastrointestinal tract.","label":0,"label_text":"Not-Related"}
+{"text":"She subsequently died some 5 weeks after the commencement of her drug therapy.Post-mortem examination showed evidence of massive hepatocellular necrosis, acute hypersensitivity myocarditis, focal acute tubulo-interstitial nephritis and extensive bone marrow necrosis, with no evidence of malignancy.","label":0,"label_text":"Not-Related"}
+{"text":"Immunofluorescent study showed granular deposits of IgG and C3 complement along glomerular basement membranes.","label":0,"label_text":"Not-Related"}
+{"text":"The child, a 4-year-old boy, had unilateral retinoblastoma with metastatic spread to the central nervous system.","label":0,"label_text":"Not-Related"}
+{"text":"Since this amount of FAB was insufficient to bind all DGTX present in the serum, cardiac DGTX toxicity (total AV-block) persisted.","label":1,"label_text":"Related"}
+{"text":"The mean time from starting MMF to the development of neutropenia was 4 months.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: Topical tacrolimus at low concentrations (0.1%) shows promise in the management of oral lichen planus-like c-GVHD.","label":0,"label_text":"Not-Related"}
+{"text":"A boy with chronic neutropenia and recurrent inflammatory skin lesions developed multiple erythematous nodules following administration of G-CSF.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: In this case of O. sulphureo-ochraceum as a human pathogen, the organism caused endophthalmitis after cataract extraction.","label":0,"label_text":"Not-Related"}
+{"text":"ADR induced by drug treatment can be a side effect of treatment with antipsychotic drugs and other drugs; however, there have been no reports of lamivudine-induced ADR in the English literature.","label":1,"label_text":"Related"}
+{"text":"Vaccine-associated herpes zoster ophthalmicus [correction of opthalmicus] and encephalitis in an immunocompetent child.","label":0,"label_text":"Not-Related"}
+{"text":"Our findings reveal that even in patients without a history of seizures, pregabalin can cause a cortical negative myoclonus.","label":1,"label_text":"Related"}
+{"text":"None of the patients treated with acyclovir had evidence of active varicella-zoster virus infection at post-mortem examination, but two had disseminated bacterial and fungal infections.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: Therapy with indapamide may induce diabetes in essential hypertension patients.","label":1,"label_text":"Related"}
+{"text":"This report describes the pathological changes in liver biopsy samples taken from 2 children who developed liver failure after combined chemotherapy for Wilms' tumor.","label":0,"label_text":"Not-Related"}
+{"text":"Fusarium infection after solid-organ transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"In deciding if tamoxifen therapy is warranted, all potentially life-threatening adverse events associated with tamoxifen should be considered, including endometrial adenocarcinoma or uterine sarcoma.","label":1,"label_text":"Related"}
+{"text":"The role of IFN-beta in inflammatory musculoskeletal disease is unclear.","label":0,"label_text":"Not-Related"}
+{"text":"Seizures occurred in two patients with probable Alzheimer's disease who were receiving long-term treatment with metrifonate, an irreversible acetylcholinesterase inhibitor.","label":1,"label_text":"Related"}
+{"text":"The case of an adult who developed both hepatic dysfunction and an impaired macrophage migration after exposure to cimetidine is discussed.","label":1,"label_text":"Related"}
+{"text":"Angiosarcoma developing after curative induction chemotherapy and radiotherapy for locally advanced squamous cell carcinoma of the larynx.","label":0,"label_text":"Not-Related"}
+{"text":"Topical dimethylsulfoxide may prevent tissue damage from anthracycline extravasation.","label":0,"label_text":"Not-Related"}
+{"text":"From 1996 to 2002 several medications were changed due to their adverse effects: indinavir (renal colic and fever), nelfinavir (cutaneous rash), and efavirenz (nausea and temporary memory loss).","label":1,"label_text":"Related"}
+{"text":"Abdomen CT scan showed diffuse circumferential thickening of ileum wall typical for ileitis, narrowing of the lumen, disturbance of peristaltic.","label":0,"label_text":"Not-Related"}
+{"text":"Awareness of the condition is therefore of continuing importance.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was successfully treated with medical management and insertion of an implantable cardioverter defibrillator.","label":0,"label_text":"Not-Related"}
+{"text":"Careful echocardiographic monitoring is indicated in such cases.","label":0,"label_text":"Not-Related"}
+{"text":"A 21-year-old man with Tourette's syndrome, pedophilia, Asperger's syndrome, and multiple sclerosis experienced seizures after receiving therapy with interferon beta-1a.","label":1,"label_text":"Related"}
+{"text":"Role of early diagnosis for a noninvasive treatment of pulmonary thromboembolism in leukemic children.","label":0,"label_text":"Not-Related"}
+{"text":"The occurrence of allergic reactions to steroids is reviewed, and suggestions for management of pulsed IV methylprednisolone therapy are made.","label":0,"label_text":"Not-Related"}
+{"text":"Acute non-lymphocytic leukemia in patients with ovarian carcinoma following long-term treatment with Treosulfan (= dihydroxybusulfan).","label":1,"label_text":"Related"}
+{"text":"Outpatient carboplatin desensitization in a pediatric patient with bilateral optic glioma.","label":0,"label_text":"Not-Related"}
+{"text":"The association of ergot toxicity and iliac dissection has not been previously described.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients with classical effort-induced angina pectoris associated with abnormal ST-segment depression on graded exercise testing and normal coronary arteriograms are described.","label":0,"label_text":"Not-Related"}
+{"text":"Norethisterone in these 69 pregnancies accounted for 33.3% (5 of 15) cases of clitoral hypertrophy diagnosed in 100,756 consecutive births.","label":1,"label_text":"Related"}
+{"text":"3 of the 5 previously untreated patients achieved biochemical and bone-marrow complete remissions.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a 54-year-old, human immunodeficiency virus-positive man with a history of sulfonamide allergy who received treatment with pentamidine for Pneumocystis jiroveci pneumonia.","label":0,"label_text":"Not-Related"}
+{"text":"Ciprofloxacin-induced toxic epidermal necrolysis in a patient with systemic lupus erythematosus.","label":1,"label_text":"Related"}
+{"text":"We report a case of calciphylaxis that may very well be due to a long-term steroid use in a rheumatoid arthritis patient who had neither end-stage renal disease nor hyperparathyroidism.","label":0,"label_text":"Not-Related"}
+{"text":"Captopril, a competitive inhibitor of angiotensin-converting enzyme, is widely used in the treatment of hypertension and heart failure.","label":0,"label_text":"Not-Related"}
+{"text":"Can ketamine prescribed for pain cause damage to the urinary tract?","label":1,"label_text":"Related"}
+{"text":"This phenomenon has been described with gentamicin though never with amikacin.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: Based on the easily managed toxicities and apparent efficacy of the regimen of weekly nab-paclitaxel and daily sunitinib, we conclude that further evaluation is warranted to assess the efficacy of this combination therapy in previously chemotherapy-treated patients with advanced thoracic cancer.","label":0,"label_text":"Not-Related"}
+{"text":"In addition, while cases of loop diuretic-induced pancreatitis, including furosemide, have been published, the allergic manifestations with both sulfonamide antibiotics and non-antibiotics in our patient suggest possible cross-reactivity between these 2 drug classes.","label":1,"label_text":"Related"}
+{"text":"A 33 year old male Nigerian presented with widespread involvement of peripheral nerves, several of which were tender and painful.","label":0,"label_text":"Not-Related"}
+{"text":"Five such patients were identified and their clinical course was reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"The patient's Ewing sarcoma remained refractory to treatment despite continuous intensified chemotherapy and was complicated by a therapy-related acute myeloid leukemia with 11q23 abnormality.","label":0,"label_text":"Not-Related"}
+{"text":"The presented case illustrates that a combined overdose of tricyclic antidepressants and neuroleptics enhances the possible toxic effects of each drug and especially the risk for adverse cardiac events.","label":0,"label_text":"Not-Related"}
+{"text":"Visual changes secondary to initiation of amiodarone: a case report and review involving ocular management in cardiac polypharmacy.","label":1,"label_text":"Related"}
+{"text":"We report a case of acute generalized exanthematous pustulosis (AGEP) in a 50-year-old woman that was attributed to the ingestion of nimesulide.","label":1,"label_text":"Related"}
+{"text":"Ofloxacin: a probable cause of toxic epidermal necrolysis.","label":1,"label_text":"Related"}
+{"text":"Intrahepatic cholestasis and cutaneous bullae associated with glibenclamide therapy are described in a 61-year-old diabetic patient who presented wit hypoglycaemic coma.","label":1,"label_text":"Related"}
+{"text":"Clevudine (L-FMAU) is a thymidine l-nucleoside analogue that was recently introduced for the treatment of chronic hepatitis B virus infection.","label":0,"label_text":"Not-Related"}
+{"text":"Distraction and relaxation training in the treatment of anticipatory vomiting: a single subject intervention.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To report a case of phenolphthalein-induced toxic epidermal necrolysis (TEN) in a patient maintained on several other medications more commonly known to be associated with TEN.","label":1,"label_text":"Related"}
+{"text":"Intravenous TMP\/SMX failed to improve the lesion.","label":0,"label_text":"Not-Related"}
+{"text":"Well-differentiated endometrial adenocarcinoma of the secretory type (FIGO Grade 1) with minimal myometrial invasion occurred in a postmenopausal patient on tamoxifen therapy 5 years after mastectomy for breast carcinoma.","label":1,"label_text":"Related"}
+{"text":"Aluminum overload can have a detrimental effect on erythropoiesis which, in turn, can blunt the effectiveness of Epoetin alfa.","label":0,"label_text":"Not-Related"}
+{"text":"Biopsy of the skin lesions revealed leukaemia cutis, which led to the discovery of acute myelogenous leukaemia.","label":0,"label_text":"Not-Related"}
+{"text":"Most patients with FH deficiency associated HUS progress to end-stage renal disease despite plasma therapy.","label":0,"label_text":"Not-Related"}
+{"text":"The injection of bulking agents into the urethral submucosa is designed to create artificial urethral cushions that can improve urethral coaptation and hence restore continence.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a 53-year-old man with Churg-Strauss syndrome and subsequent opportunistic cytomegalovirus enterocolitis.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: The recognition of this atypical presentation with a combination of opthalmoscopic, angiographic and OCT findings may avoid inappropriate diagnosis and treatment with corticosteroids.","label":0,"label_text":"Not-Related"}
+{"text":"The clinical course suggests that caffeine, which is present in oolong tea, was mainly responsible for the rhabdomyolysis as well as the delirium, although severe hyponatremia has been reported to cause rhabdomyolysis on rare occasions.","label":1,"label_text":"Related"}
+{"text":"Prolonged requirement for ventilatory support in a patient with Eskalith overdose.","label":0,"label_text":"Not-Related"}
+{"text":"However, such bacteria may also be involved in various postoperative orthopedic infections, including prosthetic joint infection.","label":0,"label_text":"Not-Related"}
+{"text":"Valproic acid is commonly and effectively used in the treatment of idiopathic generalized epilepsies, including juvenile absence epilepsy.","label":0,"label_text":"Not-Related"}
+{"text":"It is suggested that the plasma electrolytes of patients at risk should be monitored.","label":0,"label_text":"Not-Related"}
+{"text":"The increasing prevalence of methamphetamine abuse and the severity of the associated ulcers should alert ophthalmologists to the problem of methamphetamine-related keratitis.","label":1,"label_text":"Related"}
+{"text":"Three cases are described in which periorbital topical corticosteroids appear to have resulted in raised intraocular pressure or glaucoma.","label":0,"label_text":"Not-Related"}
+{"text":"Massive plasmocytosis due to methimazole-induced bone marrow toxicity.","label":1,"label_text":"Related"}
+{"text":"A 27-year-old man who had a history of bronchial asthma, eosinophilic enteritis, and eosinophilic pneumonia presented with fever, skin eruptions, cervical lymphadenopathy, hepatosplenomegaly, atypical lymphocytosis, and eosinophilia two weeks after receiving trimethoprim (TMP)-sulfamethoxazole (SMX) treatment.","label":1,"label_text":"Related"}
+{"text":"We consider asterixis to be an easily overlooked sign of neurotoxicity, which may occur even at low or moderate dosage levels, if certain drugs as lithium or clozapine are used in combination with CBZ.","label":1,"label_text":"Related"}
+{"text":"The patient was successfully treated with ciprofloxacin.","label":0,"label_text":"Not-Related"}
+{"text":"Sideroblastic anemia due to linezolid in a patient with a left ventricular assist device.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: In our patient, substantially increased glucocorticoid levels were associated with severe insulin resistance, retarded wound healing, and persistent infections.","label":0,"label_text":"Not-Related"}
+{"text":"We present the case of a 41-year-old male undergoing surgery for restenosis at the site of a repair.","label":0,"label_text":"Not-Related"}
+{"text":"He was treated with intravenous quinidine gluconate and oral doxycycline, in addition to blood transfusion, and he responded well to the treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Initially, the patient was treated with topical and systemic antibiotics, and corneal epithelium quickly regenerated.","label":0,"label_text":"Not-Related"}
+{"text":"Septic knee arthritis after intra-articular hyaluronate injection.","label":1,"label_text":"Related"}
+{"text":"Visual acuity had improved to 20\/30(+2) O.D. and 20\/30 O.S.","label":0,"label_text":"Not-Related"}
+{"text":"This report rules out other causes of toxic epidermal necrolysis and implicates ofloxacin in what appears to be an atypical presentation of drug-induced toxic epidermal necrolysis.","label":1,"label_text":"Related"}
+{"text":"A good example is the concern about using oral cobalamin when treating pernicious anemia.","label":0,"label_text":"Not-Related"}
+{"text":"We feel that hormonal treatment may be tried as first modality in the treatment of Youssef's syndrome, before resorting to surgery.","label":0,"label_text":"Not-Related"}
+{"text":"Metamizole, a nonsteroidal antiinflammatory agent, is prohibited in the United States because of the risk of agranulocytosis but is widely used in Mexico and other countries.","label":1,"label_text":"Related"}
+{"text":"Nesiritide (recombinant B-type natriuretic peptide) is often given for symptomatic relief of acute decompensated heart failure in adults.","label":0,"label_text":"Not-Related"}
+{"text":"Although the essential cause of PV is unclear, its onset has occasionally been associated with drug therapy, in particular penicillamine.","label":1,"label_text":"Related"}
+{"text":"One patient on ouabain also developed cardiomyopathy.","label":1,"label_text":"Related"}
+{"text":"Infliximab, an anti-TNFalpha antibody, was given with the aim of treating an enterocutaneous fistula, but it also produced a marked biochemical and histological improvement in the TPN-related cholestasis.","label":0,"label_text":"Not-Related"}
+{"text":"Massive pulmonary embolism due to late-onset heparin-induced thrombocytopenia following coronary artery bypass graft surgery: successful treatment with lepirudin.","label":1,"label_text":"Related"}
+{"text":"Acute eosinophilic pneumonia caused by calcium stearate, an additive agent for an oral antihistaminic medication.","label":1,"label_text":"Related"}
+{"text":"This case also constitutes an experimental model.","label":0,"label_text":"Not-Related"}
+{"text":"In rare cases mitomycin C (MMC) may induce cancer-associated hemolytic uremic syndrome, which is characterized by hemolytic anemia, thrombocytopenia and progressive renal failure.","label":1,"label_text":"Related"}
+{"text":"Because relapse of histoplasmosis may occur as long as nine years after treatment, immunocompromised patients being treated with ketoconazole must have close long-term clinical follow-up.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: A 44-year-old man taking naproxen for chronic low back pain and a 20-year-old woman on oxaprozin for rheumatoid arthritis presented with tense bullae and cutaneous fragility on the face and the back of the hands.","label":1,"label_text":"Related"}
+{"text":"We report the case of a 14-year-old female with acute promyelocytic leukemia who developed symptomatic cardiomyopathy only 4 months into treatment with a combination of daunomycin and all-trans retinoic acid (ATRA).","label":1,"label_text":"Related"}
+{"text":"Etoposide, an epipodophyllotoxin, is a topoisomerase II inhibitor that interacts with DNA to potentiate leukaemogenesis.","label":0,"label_text":"Not-Related"}
+{"text":"Acute amphotericin B overdose.","label":0,"label_text":"Not-Related"}
+{"text":"Amifostine, also known as WR-2721 (S-2-(3-aminopropylamino)-ethylphosphorothioic acid), is an organic thiophosphate cytoprotective agent used to reduce the frequency of severe xerostomia in patients with cancer undergoing postoperative radiation of the head and neck.","label":0,"label_text":"Not-Related"}
+{"text":"A new case of Creutzfeldt-Jakob disease associated with human growth hormone therapy in New Zealand.","label":1,"label_text":"Related"}
+{"text":"Recommendations are made with regard to screening such patients for glaucoma.","label":0,"label_text":"Not-Related"}
+{"text":"Multifocal inflammatory leukoencephalopathy associated with levamisole therapy.","label":1,"label_text":"Related"}
+{"text":"Long-term follow-up after neoplastic seeding complicating percutaneous ethanol injection for treatment of hepatocellular carcinoma.","label":1,"label_text":"Related"}
+{"text":"Despite a response of the meningeal tumor the patient developed in the third week of MTX treatment a progressive visual loss and loss of consciousness which worsened during subsequent Ara-C treatment and led to death within 3 weeks.","label":1,"label_text":"Related"}
+{"text":"Hypoglycemia can be a serious side effect of etanercept in patients already on antidiabetic medications known to cause hypoglycemia, such as sulfonylureas, meglitinides, and insulin.","label":1,"label_text":"Related"}
+{"text":"Risk factors present for acquired long QT syndrome were mineral dysbalance and a history of alcohol abuse with hepatic impairment.","label":0,"label_text":"Not-Related"}
+{"text":"This report addresses the association of multiple sclerosis and intracranial meningioma and discusses the effect of interferon treatment on tumour progression.","label":0,"label_text":"Not-Related"}
+{"text":"The endophthalmitis recurred after the medical treatment was discontinued.","label":0,"label_text":"Not-Related"}
+{"text":"Three patients, in whom tumour overkill by cytotoxic treatment, including high dose methotrexate with folinic acid rescue, resulted in the 'phosphate shower syndrome' (hyper-uricaemia, hyperkalaemia and hyperphosphataemia with hypocalcaemia and tetany, with metabolic acidosis and acute renal impairment) are described.","label":1,"label_text":"Related"}
+{"text":"The vomiting occurred on switching to different pancreatic enzymes preparations, ie, Creon 10, Viokase, and Pancrease MT 16.","label":1,"label_text":"Related"}
+{"text":"Pulmonary infiltrates resolved within 2 months of treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Four of five patients with ALL achieved a complete remission (CR) (including the bcr\/abl case) while among patients with AML only the one with APML achieved CR.","label":0,"label_text":"Not-Related"}
+{"text":"Colchicine has been reported to be a safe and effective medication in the treatment of early phase of Peyronie's disease (PD).","label":0,"label_text":"Not-Related"}
+{"text":"The baby was born healthy, without any anomalies.","label":0,"label_text":"Not-Related"}
+{"text":"In conclusion, the diagnosis of leflunomide-pulmonary-renal syndrome was rendered.","label":0,"label_text":"Not-Related"}
+{"text":"This rash rapidly progressed to painful hardening of the area.","label":0,"label_text":"Not-Related"}
+{"text":"Gelofusine allergy--the need for identification jewellery.","label":1,"label_text":"Related"}
+{"text":"Although calcium deficiency has not been incriminated as a cause of rickets in the past, it is possible that in very tiny premature infants rapid growth requirements lead to a relative calcium deficiency which may be manifested as uncalcified osteoid.","label":0,"label_text":"Not-Related"}
+{"text":"A whitish plaque in the lips and bilateral buccal mucosa, burning, taste disturbance, and xerostomia were observed.","label":0,"label_text":"Not-Related"}
+{"text":"Various case reports concerning dapsone-induced agranulocytosis are reviewed.","label":1,"label_text":"Related"}
+{"text":"Electromyography, muscle biopsy, and the course of the patient's illness were consistent with polymyositis.","label":0,"label_text":"Not-Related"}
+{"text":"Videopolysomnographic and pharmacokinetic studies with monitoring of plasma levodopa levels demonstrated marked motor hyperactivity during augmentation, with anarchic discharges of motor unit potentials, tonic grouped discharges and flexor spasms, associated with painful dysesthesia.","label":1,"label_text":"Related"}
+{"text":"Other potential causes of renal failure were not present in our patient and his renal function gradually recovered with the cessation of suramin treatment.","label":1,"label_text":"Related"}
+{"text":"The pathogenesis of the hypoglycemia was investigated by assessment of serum insulin, plasma glucagon and serum alanine levels during disopyramide rechallenge.","label":0,"label_text":"Not-Related"}
+{"text":"We report an additional case of isotretinoin teratogenicity in which the patient had agenesis of the cerebellar vermis, multiple leptomeningeal neuroglial heterotopias, hydrocephalus, and abnormalities of the corticospinal tracts.","label":1,"label_text":"Related"}
+{"text":"Reinstitution of penicillamine treatment caused a recurrence thus proving a causal relationship between penicillamine and the described nail-changes.","label":1,"label_text":"Related"}
+{"text":"This evidence admonishes against the prolonged use of these drugs in non-fatal disorders.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: This case describes the clinically significant increase of INR in an elderly patient after adding a chemotherapy regimen of levamisole and 5-FU to a previous regimen of warfarin alone.","label":1,"label_text":"Related"}
+{"text":"RESULTS AND CONCLUSIONS: Clonazepam provided effective relief for > 6 months in two patients with shooting\/shocking phantom limb pain.","label":0,"label_text":"Not-Related"}
+{"text":"The patient had been receiving acenocoumarol 4 mg\/d for 10 years for episodes of atrial fibrillation and recurrent deep venous thrombosis.","label":0,"label_text":"Not-Related"}
+{"text":"We report two cases of fulminant hepatic failure in HIV-1-infected patients treated with didanosine (ddI).","label":1,"label_text":"Related"}
+{"text":"A case is reported in which severe hypocalcemia, with a low plasma parathyroid hormone (PTH) concentration, resulted from the therapeutic use of magnesium sulfate for toxemia of pregnancy.","label":1,"label_text":"Related"}
+{"text":"There was no sign of bacterial, viral, or fungal infection in either case.","label":0,"label_text":"Not-Related"}
+{"text":"Limited data are available regarding this treatment in the pediatric population.","label":0,"label_text":"Not-Related"}
+{"text":"CASE: We present an 11-year old male with Budd-Chiari syndrome who experienced profound worsening of chronic aphthous ulcers after immunosuppressive therapy was changed from tacrolimus to sirolimus.","label":1,"label_text":"Related"}
+{"text":"However, peripheral neuropathy and bone marrow depression led to linezolid withdrawal in seven patients, and neuropathy may not be fully reversible in all patients.","label":1,"label_text":"Related"}
+{"text":"However, the pathogenetic mechanism has never been well investigated.","label":0,"label_text":"Not-Related"}
+{"text":"Multiagent chemotherapy alone was successful in achieving a durable remission and euthyroid state.","label":0,"label_text":"Not-Related"}
+{"text":"Gastrointestinal toxicity associated with the use of this drug is common but generally mild to moderate.","label":0,"label_text":"Not-Related"}
+{"text":"The possibility of deep vein thrombosis caused by the compression of the veins by necrotic tumor should be considered in patients with abdominal or pelvic metastases of GIST, including patients treated with imatinib.","label":1,"label_text":"Related"}
+{"text":"OBJECTIVES: The purpose of this study was to characterize the clinical features, treatment, and outcomes of patients with fungal ICD infections.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: We report two cases of pseudoporphyria caused by naproxen and oxaprozin.","label":1,"label_text":"Related"}
+{"text":"The lymphoma was of the CD4+ cytotoxic T-cell lineage, and the tumor cells also expressed CD56.","label":0,"label_text":"Not-Related"}
+{"text":"STUDY DESIGN: Case report and clinical discussion.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Chemotherapy-induced HUS was aggressively treated with plasmapheresis, high-dose steroids, vincristine and rituximab.","label":0,"label_text":"Not-Related"}
+{"text":"She had been receiving TPN for 2.5 years when she developed cholestasis which worsened despite adjustments to her TPN regimen.","label":0,"label_text":"Not-Related"}
+{"text":"Phenytoin desensitization in a child with symptomatic localization-related epilepsy.","label":0,"label_text":"Not-Related"}
+{"text":"We present a case of successful stenting of the left main coronary artery (LMCA) in a patient with ACAD.","label":0,"label_text":"Not-Related"}
+{"text":"Cross-reactivity between clindamycin and ampicillin is also demonstrated in one patient.","label":0,"label_text":"Not-Related"}
+{"text":"Biventricular thrombi in dilated cardiomyopathy: massive simultaneous pulmonary and systemic embolisation.","label":0,"label_text":"Not-Related"}
+{"text":"Cardiac arrest occurred in all patients, and four patients died.","label":0,"label_text":"Not-Related"}
+{"text":"Leflunomide-induced toxic epidermal necrolysis in a patient with rheumatoid arthritis.","label":1,"label_text":"Related"}
+{"text":"We present two sets of monozygotic twins with twin-to-twin transfusion, where in utero ductal closure occurred in the donor twin while the recipient twin appeared unaffected.","label":0,"label_text":"Not-Related"}
+{"text":"Psychosis in a 12-year-old HIV-positive girl with an increased serum concentration of efavirenz.","label":1,"label_text":"Related"}
+{"text":"Intravenous warfarin provides an alternative administration route for patients who cannot receive the oral formulation and cannot be administered subcutaneous low-molecular-weight heparins due to adverse effects.","label":0,"label_text":"Not-Related"}
+{"text":"The recognition, differential diagnosis, and management of this syndrome in children are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"However, possibly due to the bone marrow toxicity of the tuberculostatic drugs, the patient tolerated only low doses of cytostatic therapy.","label":0,"label_text":"Not-Related"}
+{"text":"INTRODUCTION-The aim of this case report is to present a 15-year follow-up of a patient with phenytoin (PHT) intoxication with unilateral gingival hyperplasia (GH).","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: The two reported cases of tocolysis-induced vulvar edema were not fatal and resolved after repositioning the patient in one case and by cesarean section in the other.","label":0,"label_text":"Not-Related"}
+{"text":"Inadvertent and accidental epinephrine overdose might result in potentially lethal complications.","label":1,"label_text":"Related"}
+{"text":"Treatment of proteinuria with low-molecular-weight heparin after renal transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"Metformin-associated lactic acidosis (MALA) is a serious metabolic complication that occurs because of metformin accumulation in patients who become dehydrated or developed acute renal failure.","label":1,"label_text":"Related"}
+{"text":"These myths underscore the importance and utility of outcome-based research to help guide physicians in their practices.","label":0,"label_text":"Not-Related"}
+{"text":"A comparison of the pharmacological actions of successful and unsuccessful treatments for AHC is made.","label":0,"label_text":"Not-Related"}
+{"text":"Associated clinical and electrophysiological polyradiculopathy and multiple mononeuropathy of the lower extremities were observed.","label":0,"label_text":"Not-Related"}
+{"text":"Marked sinus tachycardia resulting from the synergistic effects of marijuana and nortriptyline.","label":1,"label_text":"Related"}
+{"text":"Cefoxitin therapy for Mycobacterium fortuitum bacteremia with associated granulomatous hepatitis.","label":1,"label_text":"Related"}
+{"text":"We report an allogeneic bone marrow transplant recipient who developed CMV infection refractory to sequential therapy with ganciclovir, foscarnet, and cidofovir.","label":1,"label_text":"Related"}
+{"text":"The purpose of this report is to document a new case of in utero CP exposure with multiple congenital anomalies and to establish an apparent CP embryopathy phenotype.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND: NVP is a non-nucleoside reverse transcriptase inhibitor used in the treatment of Human Immunodeficiency Virus (HIV) infection.","label":0,"label_text":"Not-Related"}
+{"text":"Naloxone, a pure opioid antagonist, has demonstrated reversal effects from clonidine intoxication.","label":0,"label_text":"Not-Related"}
+{"text":"None of the seven patients receiving MPP on PUVA had a reaction.","label":0,"label_text":"Not-Related"}
+{"text":"Withdrawal syndromes, delirium tremens in particular, are known to cause delirium.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: Significant ocular complications such as an irreversible decrease of visual acuity may develop in patients treated with pegylated interferon.","label":1,"label_text":"Related"}
+{"text":"Throughout the patient's clinical course, the activity of plasma VWF-cleaving protease, which specifically cleaves the Tyr842-Met843 bond of the subunit and reduces its multimeric sizes, was quite normal (95-119%).","label":0,"label_text":"Not-Related"}
+{"text":"Two patients treated with 5-fluorouracil (5-FU) for disseminated adenocarcinoma of the colon developed cerebellar dysfunction typical of 5-FU neurotoxicity.","label":1,"label_text":"Related"}
+{"text":"CCBs should be considered in the treatment of 5-FU or capecitabine-induced headaches.","label":1,"label_text":"Related"}
+{"text":"The steps that can be taken to promptly reach a diagnosis and to successfully treat this life-threatening condition are described.","label":0,"label_text":"Not-Related"}
+{"text":"It is the first case of ciprofloxacin-induced VBDS successfully treated with tacrolimus.","label":1,"label_text":"Related"}
+{"text":"Additive pulmonary toxicity with melphalan and busulfan therapy.","label":1,"label_text":"Related"}
+{"text":"A 51-year-old woman who had repeated episodes of dizziness, nausea, and vomiting was diagnosed with vertebrobasilar insufficiency.","label":0,"label_text":"Not-Related"}
+{"text":"It is sometimes the sorrow of failed action and sometimes the sorrow of failed conduct.","label":0,"label_text":"Not-Related"}
+{"text":"Terbutaline for chronotropic support in heart transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"She received an accidental 450-mg bolus injection of morphine intrathecally and developed hypertension, status epilepticus, intracerebral hemorrhage, and respiratory failure.","label":1,"label_text":"Related"}
+{"text":"We introduce a case of a sixty years old woman with several previous episodes of rhinitis, conjunctivitis and perspiration immediately after the administration of salmon calcitonin with nasal spray or intramuscular administration (Calsynar).","label":1,"label_text":"Related"}
+{"text":"INTERVENTIONS AND RESULTS: Cardiac complications were observed in five pediatric patients who received between 4.6 and 40.8 mg\/kg\/d of amphotericin B.","label":1,"label_text":"Related"}
+{"text":"Cutaneous plasmacytoma is an uncommon observation in clinical practice.","label":0,"label_text":"Not-Related"}
+{"text":"The current report describes a man who was prescribed zonisamide for epilepsy and subsequently developed widespread skin rash, acute kidney injury, high-grade fever, eosinophilia, liver dysfunction, lymphadenopathy and an increase in antihuman herpesvirus-6 immunoglobulin G titer.","label":1,"label_text":"Related"}
+{"text":"Doses of 0.8-1.0 mg\/kg of L-AmpB were administered intravenously every 24-72 hr.","label":0,"label_text":"Not-Related"}
+{"text":"He ran out of medication, was unable to refill his prescription for 2 days and presented to the emergency department in status epilepticus.","label":0,"label_text":"Not-Related"}
+{"text":"DISCUSSION: This case shows that switching to zidovudine potentially can lead to a hyperlactatemia relapse.","label":1,"label_text":"Related"}
+{"text":"On the basis of survival data, it is not clear that use of MTX adversely affected the natural course of their HIV disease.","label":0,"label_text":"Not-Related"}
+{"text":"The treatment of paracetamol overdose with charcoal haemoperfusion and cysteamine.","label":0,"label_text":"Not-Related"}
+{"text":"The hypothyroid status was corrected by increasing the dose of levothyroxine.","label":0,"label_text":"Not-Related"}
+{"text":"In rare cases mitomycin C (MMC) may induce cancer-associated hemolytic uremic syndrome, which is characterized by hemolytic anemia, thrombocytopenia and progressive renal failure.","label":1,"label_text":"Related"}
+{"text":"The clinical presentation and management of a newborn whose mother received lithium during pregnancy is presented.","label":0,"label_text":"Not-Related"}
+{"text":"The gross appearance of the tumor during surgery was typical of neurilemmoma.","label":0,"label_text":"Not-Related"}
+{"text":"We report three cases of IFN beta induced hepatitis in MS and discuss the pathology findings and possible mechanisms of drug-induced liver injury.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: This report shows thatimmune-mediateddiabetes mellitus can occur as a late complication of alfa-interferon therapy.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Confocal microscopy can be a useful, noninvasive imaging technique helpful in the study, diagnosis, and treatment of Acanthamoeba keratitis.","label":0,"label_text":"Not-Related"}
+{"text":"The patient died of respiratory failure after 8 days of steroid infusion and erlotinib discontinuation.","label":0,"label_text":"Not-Related"}
+{"text":"A skin biopsy specimen disclosed intracorneal pustule composed of neutrophils and lymphohistiocytic infiltrate in the dermis.","label":0,"label_text":"Not-Related"}
+{"text":"Prolongation of the QT interval associated with ventricular arrhythmias has been the most common cause of the restriction or withdrawal of drugs from the market in the past 10 years.","label":0,"label_text":"Not-Related"}
+{"text":"To date, only three cases of seizures associated with amphotericin B have been reported in the literature, but healthcare providers should be aware of the potential for this rare adverse effect.","label":1,"label_text":"Related"}
+{"text":"In two patients opportunistic infections did not develop.","label":0,"label_text":"Not-Related"}
+{"text":"A case history of a 15-year-old boy who developed incapacitating tardive dyskinesia that resolved during treatment with deanol is presented.","label":1,"label_text":"Related"}
+{"text":"Transient paralysis associated with epidural steroid injection.","label":0,"label_text":"Not-Related"}
+{"text":"Thereafter, Mycobacterium tuberculosis was detected in blood cultures and specimens of bronchoalveolar lavage, thus indicating disseminated TB.","label":0,"label_text":"Not-Related"}
+{"text":"Multifocal ERG showed abnormalities that sometimes correlated with the visual field appearance and confirmed that the deficit occurs at the retinal level.","label":0,"label_text":"Not-Related"}
+{"text":"Although the treatment of S. aureus endocarditis in immunosuppressed transplant patients has traditionally resulted in loss of their allograft, prompt diagnosis and appropriate antibiotics with continued immunosuppressive therapy resulted in a successful outcome and allograft preservation in this case.","label":0,"label_text":"Not-Related"}
+{"text":"Microscopic examination of random colonic biopsies by two consecutive sigmoidoscopies revealed angulated crystals with a characteristic crystalline mosaic pattern on the ulcerated mucosa, which were consistent with Kayexalate crystals.","label":0,"label_text":"Not-Related"}
+{"text":"We describe the clinical and biological characteristics and outcome of five patients with post-HSCT MN, review the previously reported cases and discuss the pathogenic aspects of this nephropathy.","label":0,"label_text":"Not-Related"}
+{"text":"Prenatal cytomegalovirus (CMV) infection associated with severe brain damage was detected in an infant whose mother had been treated with prednisolone and azathioprine for systemic lupus erythematosus (SLE).","label":1,"label_text":"Related"}
+{"text":"Myoclonus and EEG bursts were both spontaneous and stimulus induced.","label":0,"label_text":"Not-Related"}
+{"text":"Following prompt recognition and diagnosis, intravenous thrombolytic therapy was administered 2 hours after symptom onset.","label":0,"label_text":"Not-Related"}
+{"text":"A 27-year-old man who had a history of bronchial asthma, eosinophilic enteritis, and eosinophilic pneumonia presented with fever, skin eruptions, cervical lymphadenopathy, hepatosplenomegaly, atypical lymphocytosis, and eosinophilia two weeks after receiving trimethoprim (TMP)-sulfamethoxazole (SMX) treatment.","label":1,"label_text":"Related"}
+{"text":"Vancomycin is widely used against methicillin-resistant Staphylococcus aureus infections, but it is associated with many adverse effects such as nephrotoxicity, ototoxicity, gastrointestinal disturbances, blood disorders, and two types of hypersensitivity reactions - an anaphylactoid reaction known as \"red man syndrome\" and anaphylaxis.","label":1,"label_text":"Related"}
+{"text":"The condition is primarily reported in patients with end-stage renal disease, and is associated with significant morbidity and mortality.","label":0,"label_text":"Not-Related"}
+{"text":"Clostridium difficile toxin-induced colitis after use of clindamycin phosphate vaginal cream.","label":1,"label_text":"Related"}
+{"text":"All patients had temporary relief of signs or symptoms of inflammation.","label":0,"label_text":"Not-Related"}
+{"text":"Six weeks later a more severe syndrome of dysarthria and ataxia developed during a second cycle of treatment.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of a patient who experienced severe depressive symptoms after both the first and second course of treatment with a corticosteroid during chemotherapy and ultimately committed suicide.","label":0,"label_text":"Not-Related"}
+{"text":"We share our experience in the treatment of candida peritonitis using oral fluconazole.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Priapism is an uncommon but potentially serious adverse effect of zuclopenthixol that practitioners, as with many other antipsychotics, should be aware of.","label":1,"label_text":"Related"}
+{"text":"She was placed on adjuvant Adriamycin (doxorubicin) chemotherapy, but 6 months later died of Adriamycin toxicity.","label":1,"label_text":"Related"}
+{"text":"In 6 of 10 patients, several treatment attempts either had failed or could not be used due to severe side effects or underlying disease.","label":0,"label_text":"Not-Related"}
+{"text":"These cases indicate the potential for development of acral cyanosis, livedo reticularis, or Raynaud symptoms with these medications and their potential contribution to a vasculopathy.","label":0,"label_text":"Not-Related"}
+{"text":"Minocycline as a cause of drug-induced autoimmune hepatitis.","label":1,"label_text":"Related"}
+{"text":"Resolution of a giant atrial thrombus following anticoagulation therapy.","label":0,"label_text":"Not-Related"}
+{"text":"A treatment attempt with allopurinol was initiated while antiviral therapy was continued and was successfully completed after 6 months.","label":0,"label_text":"Not-Related"}
+{"text":"The effusion resolved after the withdrawal of the drug and the beginning of anti-inflammatory therapy; there was no relapse during a 10-month follow-up.","label":0,"label_text":"Not-Related"}
+{"text":"After induced delivery at term because of hypertension, repeated laboratory findings showed increased aspartate aminotransferase (AST) and alanine aminotransferase (ALT) and negative hepatitis C and B markers.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a case of intraoperative gelatine-induced anaphylaxis whose diagnosis was delayed as the use of gelatine during surgical procedures was omitted for two times in patient's medical records.","label":1,"label_text":"Related"}
+{"text":"Risks from use of a prescription drug for other than the intended patient are also highlighted by this episode of poisoning.","label":0,"label_text":"Not-Related"}
+{"text":"After extensive neurological 'work up', we realized that the anisocoria was related to the transdermal scopolamine patch that we had prescribed for weaning off the opioid.","label":1,"label_text":"Related"}
+{"text":"Sturge Weber syndrome with intraoral manifestations.","label":0,"label_text":"Not-Related"}
+{"text":"The patient underwent acute oliguric renal failure, which required treatment with hyperhydration, urine alkalinization, urate oxidase and hemodialysis, with a fatal evolution.In conclusion, the present case report has several peculiarities: that of being one of the rare examples of spontaneous TLS, that of showing an exceptionally severe hyperuricemia, probably the highest ever reported in the literature, and that of the possible increased risk of tumours in patients with Crohn s disease taking inmunosuppressives and\/or TNF antagonists.","label":0,"label_text":"Not-Related"}
+{"text":"Medical misadventure = human tragedy.","label":0,"label_text":"Not-Related"}
+{"text":"A month later, he developed clinical and biochemical evidence of modest hepatocellular injury, and therapy was stopped.","label":0,"label_text":"Not-Related"}
+{"text":"Chronic hypotension, infrequent though possible in chronic renal failure patients on hemodialysis, has harmful consequences on their physical state and hence general well-being.","label":0,"label_text":"Not-Related"}
+{"text":"Methyldopa-induced liver injury.","label":1,"label_text":"Related"}
+{"text":"Therapeutic re-exposure with intravenous ceftriaxone 1 g confirmed the diagnosis.","label":0,"label_text":"Not-Related"}
+{"text":"Atropine 1 mg given intravenously resulted in shortening of all P-P intervals without changing the rhythm.","label":0,"label_text":"Not-Related"}
+{"text":"Careful follow-up of so-called \"self-limited\" insulin edema is encouraged, and the early institution of diuretic therapy is advocated in elderly patients to prevent the development of overt cardiac failure.","label":1,"label_text":"Related"}
+{"text":"Extra caution should be taken in using octreotide or its long-acting analog in patients otherwise predisposed to intrahepatic bile stasis.","label":1,"label_text":"Related"}
+{"text":"Thirty-nine cases are reviewed in which the patients developed a hemolytic-uremic-like syndrome, apparently in response to chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Corynebacterium Group JK pathogen in cerebrospinal fluid shunt infection.","label":0,"label_text":"Not-Related"}
+{"text":"With a median follow-up of 13 months (12 to 17 months), all five patients are well and have shown stable or improved performance status and clinical remission of organ-related dysfunction, including a 50% reduction in daily proteinuria with no change in creatinine, reversal of symptoms of cardiomyopathy and reductions of posterior wall and septal thickening, reversal of polyneuropathy and gastric atony, and resolution of hepatomegaly by computed tomographic scan.","label":0,"label_text":"Not-Related"}
+{"text":"CASE SUMMARY: A 41-year-old woman with a history of proliferative glomerulonephritis from systemic lupus erythematosus was admitted with a diagnosis of cryptococcal meningitis.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a relatively healthy, 9-year-old boy who developed a CA-MRSA skin and soft tissue infection and was treated with TMP-SMX.","label":1,"label_text":"Related"}
+{"text":"We suggest that nicotinic acid was the cause of his liver disease, that this case is of particular note because of the rather short period of therapy before the onset of liver injury and the severity of the hepatic failure, and that the probable increased use of nicotinic acid for serum cholesterol control makes it especially important for physicians and their patients to be alert to the signs of hepatotoxicity.","label":1,"label_text":"Related"}
+{"text":"The patient received the three agents as short infusions over four consecutive days.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: We used immunological methods to study a case in which pemphigus herpetiformis occurred in a woman with a history of psoriasis, shortly after a course of ultraviolet B (UVB) therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Orthodontic treatment of patients using bisphosphonates: a report of 2 cases.","label":0,"label_text":"Not-Related"}
+{"text":"Gelatinous transformation of the marrow (GTBM) has been associated with various conditions.","label":0,"label_text":"Not-Related"}
+{"text":"Pneumocystis pneumonia should be considered in asthmatic patients taking methotrexate who present with fever, pulmonary infiltrates, and hypoxia.","label":1,"label_text":"Related"}
+{"text":"Three of the dogs died.","label":0,"label_text":"Not-Related"}
+{"text":"Our patient's symptoms were resolved when tacrolimus was substituted for cyclosporine and amlodipine was initiated.","label":0,"label_text":"Not-Related"}
+{"text":"Experience with continuous haloperidol infusions is growing, and it appears to be an effective method for control of severe agitation or delirium.","label":0,"label_text":"Not-Related"}
+{"text":"Anisocoria from transdermal scopolamine.","label":1,"label_text":"Related"}
+{"text":"The follow-up images showed complete occlusion of the pseudoaneurysm after the thrombin injection.","label":0,"label_text":"Not-Related"}
+{"text":"These observations are consistent with the hypothesis that angiotensin-converting enzyme inhibition may cause anemia by increasing renal blood flow and consequently decreasing erythropoietin levels.","label":0,"label_text":"Not-Related"}
+{"text":"Portal hypertension in a patient with chronic myeloid leukaemia.","label":0,"label_text":"Not-Related"}
+{"text":"The typical manifestation is an urticarial or erythematous rash, and pruritus on the face and flexural aspects of limbs, followed by progression to dermatitis.","label":0,"label_text":"Not-Related"}
+{"text":"Polycystic ovarian disease, a condition characterized by unopposed estrinism due to the peripheral conversion of excessive androstenedione to estrone, was found in a 27-year-old infertile woman with an endometrial malignant mullerian mixed tumor.","label":0,"label_text":"Not-Related"}
+{"text":"We have described a man with classic rheumatoid arthritis who had membranous nephropathy associated with nephrotic syndrome not related to gold or penicillamine therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Radiation-induced fibrosis (RIF) is a terminal sequela to irradiation that does not regress spontaneously.","label":0,"label_text":"Not-Related"}
+{"text":"The risk of cardiac decompensation in infants with supraventricular tachycardia and congestive cardiac failure should be kept in mind prior to administration of verapamil.","label":1,"label_text":"Related"}
+{"text":"However, many of the patients had been treated surgically for recurrences once or several times previously.","label":0,"label_text":"Not-Related"}
+{"text":"The cause of these previously unreported side effects of niacin therapy is uncertain but may be related to prostaglandin-mediated vasodilatation, hyperalgesia of sensory nerve receptors, and potentiation of inflammation in the gingiva with referral of pain to the teeth.","label":1,"label_text":"Related"}
+{"text":"Both patients were normal in the initial study, but later developed pathological diploid cell lines with structural chromosome abnormalities.","label":0,"label_text":"Not-Related"}
+{"text":"A standard verteporfin dose was given and a photodynamic treatment (PDT) protocol was followed.","label":0,"label_text":"Not-Related"}
+{"text":"The patient underwent radical cystectomy and an ileal conduit was created.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: These results suggest that rifampin-impregnated silicone catheters could become a valuable tool in the treatment and prevention of shunt infections.","label":0,"label_text":"Not-Related"}
+{"text":"A brief discussion of this case and the use of digoxin-specific antibodies is presented.","label":0,"label_text":"Not-Related"}
+{"text":"Here we report an unusual case of mixed Wilms' tumour and angiosarcoma in a 38-year-old female patient who presented with haematuria and right lower back pain.","label":0,"label_text":"Not-Related"}
+{"text":"He developed recurrent skin rash, fever, hypereosinophilia, and acute renal failure after rechallenge with chlorambucil.","label":1,"label_text":"Related"}
+{"text":"The alpha(1)-adrenoceptor occupancy by endogenous norepinephrine was increased in a dose-dependent manner by milnacipran, whereas fluvoxamine had essentially no effect.","label":0,"label_text":"Not-Related"}
+{"text":"Incorrect identification of the organism as Corynebacterium J-K led to a change of antimicrobial therapy and clinical deterioration.","label":0,"label_text":"Not-Related"}
+{"text":"Unexpectedly, the patient developed a severe skin reaction in the region exposed to the radiation field, and a bilateral subdural hemorrhage, following radiation therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Early recognition of hereditary motor and sensory neuropathy type 1 can avoid life-threatening vincristine neurotoxicity.","label":1,"label_text":"Related"}
+{"text":"Electron microscopy showed morphological abnormalities in the matrix.","label":0,"label_text":"Not-Related"}
+{"text":"That review suggested that patients receiving anti-D IGIV be monitored for those and other potential complications of hemoglobinemia, particularly disseminated intravascular coagulation (DIC).","label":1,"label_text":"Related"}
+{"text":"An anaplastic large cell lymphoma that was negative for Epstein-Barr virus and positive for Ki-1 (CD30) presented as a polypoid scalp mass in a 56-year-old man 16 years after renal transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"Many symptoms of hyperthyroidism are identical to the adverse effects of the commonly used inhaled bronchodilators and include tremor, nervousness, tachycardia, wide pulse pressure, palpitations, emotional lability, agitation, nightmares, aggressive behavior, and diarrhea.","label":0,"label_text":"Not-Related"}
+{"text":"Dysgammaglobulinemia in steroid-dependent optic neuritis: response to gammaglobulin treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Withdrawal emergent syndrome in an infant associated with maternal haloperidol therapy.","label":1,"label_text":"Related"}
+{"text":"After desensitization, phenytoin-specific CFSElow CD4+ cells decreased to background level.","label":0,"label_text":"Not-Related"}
+{"text":"Impetigo herpetiformis is a rare non-infectious pustular dermatosis of pregnancy.","label":0,"label_text":"Not-Related"}
+{"text":"Rupture of the plantar fascia.","label":0,"label_text":"Not-Related"}
+{"text":"Recently there have been concerns relating to liver and now kidney toxicity.","label":0,"label_text":"Not-Related"}
+{"text":"Isoniazid and ethambutol as a cause of optic neuropathy.","label":1,"label_text":"Related"}
+{"text":"The risk of developing BMTN may be greater with the use of more intensive chemotherapy and higher total body and tumor bed irradiation.","label":0,"label_text":"Not-Related"}
+{"text":"CASE REPORT: We report the case of a 58 year old patient who, after 2 days of treatment with roxithromycin and betamethasone, manifested acute pancreatitis.","label":1,"label_text":"Related"}
+{"text":"Emergency selective coronary angiography was performed.","label":0,"label_text":"Not-Related"}
+{"text":"Bicarbonate hemodialysis treatment should take place early in the course of management, especially in patients with severe metabolic acidosis who fail to respond to intravenous bicarbonate therapy or in whom renal failure is present.","label":0,"label_text":"Not-Related"}
+{"text":"We report two cases of F. oryzihabitans bacteraemia associated with the use of Hickman catheters for administration of the patients' chemotherapeutic agents.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: Serial amniocentesis may place patients at elevated risk for Candida chorioamnionitis and subsequent preterm delivery.","label":0,"label_text":"Not-Related"}
+{"text":"In fact, to our knowledge only 37 cases, including this one, have been documented.","label":0,"label_text":"Not-Related"}
+{"text":"Before treatment thyroid function tests were normal and anti-thyroid (anti-thyroglobulin and anti-thyroid peroxidase) Abs were negative.","label":0,"label_text":"Not-Related"}
+{"text":"Thus, the transient increase in blood glucose was not related to a pre-diabetic status.","label":0,"label_text":"Not-Related"}
+{"text":"It is currently undergoing evaluation as an adjunct to bone marrow transplantation but its use in patients with metabolic disorders, such as Hurler's syndrome (HS), has not been explored.","label":0,"label_text":"Not-Related"}
+{"text":"Mitoxantrone and cyclophosphamide in advanced breast cancer: a pilot study.","label":0,"label_text":"Not-Related"}
+{"text":"This phenomenon is the main feature of the dopamine dysregulation syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"A 51-year-old man developed type 1 diabetes mellitus following 24 weeks of treatment with recombinant alpha-2b peginterferon plus ribavirin for chronic hepatitis C.","label":1,"label_text":"Related"}
+{"text":"A case of steroid induced exophthalmos in a patient with systemic lupus erythematosus with renal involvement is described.","label":0,"label_text":"Not-Related"}
+{"text":"Tumor lysis syndrome after transcatheter arterial infusion of cisplatin and embolization therapy for liver metastases of melanoma.","label":1,"label_text":"Related"}
+{"text":"RESULTS: A 52-year-old woman with Parkinson disease who had taken amantadine for 6 years had bilateral corneal edema for 2 months at baseline.","label":1,"label_text":"Related"}
+{"text":"DISCUSSION: In general however, it must be remembered that problems with oral hypoglycaemics are rare.","label":0,"label_text":"Not-Related"}
+{"text":"The most common complication associated with this procedure is an alteration in sensation over the donor site manifested as chronic pain, hyperesthesia, dysesthesia, or diminished sensitivity resulting from superior cluneal nerve (SCN) injury.","label":0,"label_text":"Not-Related"}
+{"text":"In addition, patients with clinical signs suggestive of NMS should be monitored more carefully.","label":0,"label_text":"Not-Related"}
+{"text":"INVESTIGATIONS: Physical examination, cerebral MRI, brain biopsy, skin biopsy, immunohistochemistry, bronchoscopy with bronchoalveolar lavage, and laboratory tests.","label":0,"label_text":"Not-Related"}
+{"text":"PURPOSE: To describe bilateral corneal endothelial dysfunction in a patient with Parkinson disease who was treated with long-term amantadine.","label":1,"label_text":"Related"}
+{"text":"Levosimendan infusion was started at the sixth hour of cardiopulmonary bypass circulation.","label":0,"label_text":"Not-Related"}
+{"text":"During clarithromycin coadministration, four out of the seven patients developed moderate-to-severe toxic symptoms of carbamazepine, such as drowsiness, dizziness, and ataxia, which resolved within 5 days after clarithromycin discontinuation.","label":1,"label_text":"Related"}
+{"text":"All patients were under immunosuppressive therapy.","label":0,"label_text":"Not-Related"}
+{"text":"A patient with a right atrial thrombus and recurrent pulmonary emboli secondary to permanent pacemaker insertion is described.","label":0,"label_text":"Not-Related"}
+{"text":"A marked decrease of the free form of protein S was documented.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: A 37-year-old African- American man with G6PD deficiency developed hemolytic anemia, hepatitis, orthostatic hypotension, and aseptic meningitis simultaneously after using trimethoprim-sulfamethoxazole.","label":1,"label_text":"Related"}
+{"text":"Calciphylaxis in a patient with rheumatoid arthritis without renal failure and hyperparathyroidism: the possible role of long-term steroid use and protein S deficiency.","label":0,"label_text":"Not-Related"}
+{"text":"In four of five eyes the LASIK flap was amputated.","label":0,"label_text":"Not-Related"}
+{"text":"Corticosteroid therapy was continued for 8 months since there was still improvement of pulmonary function studies.","label":0,"label_text":"Not-Related"}
+{"text":"We report two cases of cerebrospinal fluid eosinophilia (CSFE) secondary to the intraventricular administration of vancomycin.","label":1,"label_text":"Related"}
+{"text":"An initial dose of intraventricular vancomycin should take into account volume of distribution (ventricular size) to obtain a peak cerebrospinal fluid concentration of 20 to 30 micrograms\/mL.","label":0,"label_text":"Not-Related"}
+{"text":"Older therapies that have been widely accepted for a long time might not have had controlled trial data behind recommendations for their use, and once practice patterns become widespread, it is hard to change.","label":0,"label_text":"Not-Related"}
+{"text":"Myasthenia gravis during low-dose IFN-alpha therapy for chronic hepatitis C.","label":1,"label_text":"Related"}
+{"text":"The pathophysiology of the syndrome is unknown.","label":0,"label_text":"Not-Related"}
+{"text":"Although this therapy has a very low toxicity profile, an increase in secondary cancers has been reported.","label":0,"label_text":"Not-Related"}
+{"text":"Since recent studies have reported no negative interactions with concurrent use, we here report three cases (one case of a prolonged seizure, a serotonin syndrome and a focal seizure) of severe lithium-induced side effects while patients underwent ECT without complications and lithium serum levels were still subtherapeutic.","label":1,"label_text":"Related"}
+{"text":"Despite the administration of high doses of rhEPO, toxicity attributable to rhEPO was not observed in either the double-blind or open-label study.","label":0,"label_text":"Not-Related"}
+{"text":"Number twenty-one.","label":0,"label_text":"Not-Related"}
+{"text":"Due to paranoia and agitation, the dose was increased to 5 mg twice daily after 2 days.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: Our purpose was to test the efficacy of stanozolol, a drug capable of fibrinolytic enhancement, in treating cutaneous ulcers caused by cryofibrinogenemia.","label":0,"label_text":"Not-Related"}
+{"text":"Epstein-Barr virus-associated lymphoproliferative disease (EBV-LPD) is a serious disorder seen in various states of immunodeficiency, often with a fatal outcome.","label":0,"label_text":"Not-Related"}
+{"text":"He reported adherence to drug therapy and diet.","label":0,"label_text":"Not-Related"}
+{"text":"Cerebral infarcts in a pediatric patient secondary to phenylpropanolamine, a recalled medication.","label":1,"label_text":"Related"}
+{"text":"A high dose of cotrimoxazole induced hyperkalaemia with the elevation of serum creatinine and blood urea, and increased urinary N-acetyl glucosaminase after several days of the drug administration in these patients; one patient became unconscious.","label":1,"label_text":"Related"}
+{"text":"We report a case of a patient with pulmonary hypertension and undifferentiated connective tissue disease who, after 2 months of treatment with epoprostenol, presented with rapidly progressive erythema, scaling, nausea and vomiting, and fever.","label":1,"label_text":"Related"}
+{"text":"The patient received bleomycin 189 U over five days for preoperative control of a squamous cell carcinoma of the right tongue and tonsil.","label":0,"label_text":"Not-Related"}
+{"text":"Three distinct types of minocycline-induced cutaneous pigmentation have been described.","label":1,"label_text":"Related"}
+{"text":"However, acute cardiomyopathy and pericarditis secondary to methylphenidate use has been rarely reported.","label":1,"label_text":"Related"}
+{"text":"Serum tryptase levels after intramuscular challenge did not increase significantly with regard to the basal levels.","label":0,"label_text":"Not-Related"}
+{"text":"Concomitant aspiration of gastric acid was thought to be the explanation for the severity of these cases.","label":0,"label_text":"Not-Related"}
+{"text":"Niemann-Pick type C is an autosomal-recessive, neurovisceral storage disorder that results from defective cholesterol esterification.","label":0,"label_text":"Not-Related"}
+{"text":"Medication can induce severe ulcerations.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: The patient was treated with immediate corticosteroids at the time of initial diagnosis, and emergent re-exploration and debulking of the paraspinal muscles.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: A 36-year-old man sustained a flap dehiscence following traumatic right eye gouging by a seagull claw.","label":0,"label_text":"Not-Related"}
+{"text":"Also, transcranial Doppler revealed approximate doubling of blood flow velocity in vertebral artery area compared with her baseline value.","label":0,"label_text":"Not-Related"}
+{"text":"A 63-year-old man with rheumatoid arthritis presented with pain and swelling of his right buttock.","label":0,"label_text":"Not-Related"}
+{"text":"Although she had been in complete remission (CR), the structure of the left lung was severely degraded.","label":0,"label_text":"Not-Related"}
+{"text":"SCs increase during chemotherapy, were often unpredictable and led to emotional consequences.","label":0,"label_text":"Not-Related"}
+{"text":"Dose-dependent olanzapine-associated leukopenia: three case reports.","label":1,"label_text":"Related"}
+{"text":"He recommends evaluation for a pulmonary or ophthalmologic injury.","label":0,"label_text":"Not-Related"}
+{"text":"Chymopapain should have been released by the FDA on a Phase IV basis.","label":0,"label_text":"Not-Related"}
+{"text":"This report describes the initial protocol, the gingivectomy, and a 2-year follow-up.","label":0,"label_text":"Not-Related"}
+{"text":"Pulmonary edema as a delayed complication of ritodrine therapy.","label":1,"label_text":"Related"}
+{"text":"In this report we described a case of juvenile idiopathic arthritis patient who developed thymic enlargement (true thymic hyperplasia), mediastinal lymphadenopathy and pleurisy associated with systemic symptoms under Etanercept treatment.","label":1,"label_text":"Related"}
+{"text":"Acute lymphoblastic leukemia as a second malignant neoplasm in a child with medulloblastoma.","label":0,"label_text":"Not-Related"}
+{"text":"Pure red cell aplasia associated with fenoprofen.","label":1,"label_text":"Related"}
+{"text":"OBJECTIVE: To describe a case of exacerbated mania potentially related to an interaction between lopinavir\/ritonavir and valproic acid (VPA) and propose a mechanism of action for this interaction.","label":1,"label_text":"Related"}
+{"text":"Actinomycosis of the female genital tract has greatly increased over the last two decades.","label":0,"label_text":"Not-Related"}
+{"text":"Overall, SMS 201-995 appears to be a valuable new agent for the treatment of acromegaly, but long-term safety needs to be established.","label":0,"label_text":"Not-Related"}
+{"text":"We present a case of an elderly woman with a pre-existing history of ischaemic heart disease, who was treated with venlafaxine, and developed acute myocardial ischaemia within the first week of treatment.","label":1,"label_text":"Related"}
+{"text":"The treatment was discontinued and after 2 months the liver parameters became normal.","label":0,"label_text":"Not-Related"}
+{"text":"We report 4 patients, 2 on methylphenidate and 2 on dextroamphetamine who presented with acral cyanosis, livedo reticularis, or Raynaud phenomenon.","label":1,"label_text":"Related"}
+{"text":"A chronic reaction associated with long-term treatment with nitrofurantoin has also been reported and causes irreversible pulmonary fibrosis.","label":1,"label_text":"Related"}
+{"text":"We observed 3 diabetic patients with intolerable dizziness followed by nausea and vomiting immediately after an initial administration of the alpha-glucosidase inhibitor, voglibose.","label":1,"label_text":"Related"}
+{"text":"Effectiveness of pentostatin (2'-deoxycoformycin) in refractory lymphoid neoplasms.","label":0,"label_text":"Not-Related"}
+{"text":"Laryngeal dyspnea in relation to an interaction between acenocoumarol and topical econazole lotion.","label":1,"label_text":"Related"}
+{"text":"Most patients are treated conservatively because an improvement occurs when the absolute neutrophil count rises.","label":0,"label_text":"Not-Related"}
+{"text":"Opioid-related narcosis in a woman with myopathy receiving magnesium.","label":0,"label_text":"Not-Related"}
+{"text":"This is an interesting case because the proarrhthmia of the drug was not tachyarrhythmia, such as ventricular tachycardia or torsades de pointes, but sinus pause.","label":0,"label_text":"Not-Related"}
+{"text":"A careful history and examination, with appropriate investigations, can lead to an accurate diagnosis in such difficult cases.","label":0,"label_text":"Not-Related"}
+{"text":"Although the exact pathophysiological processes involved have not yet been established, the neurotransmitters dopamine, serotonin and gamma amino butyric aid (GABA) have been documented to play a significant role in the generation of hiccups.","label":0,"label_text":"Not-Related"}
+{"text":"Mean time between initiation of gemcitabine therapy and onset of HUS was 7.4 +\/- 3.5 months, or 21.9 +\/- 10.9 doses of gemcitabine.","label":1,"label_text":"Related"}
+{"text":"Awareness of this unusual side-effect may prevent needless investigation and therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Paradoxical exacerbation of the signs and symptoms of tuberculosis may occur not only after antituberculosis therapy, but also soon after the initiation of a potent combination of antiretroviral drugs in human immunodeficiency virus (HIV) serpositive patients with tuberculosis.","label":0,"label_text":"Not-Related"}
+{"text":"The patients were transferred to intensive care unit, and the treatment was continued after administration of corticosteroids under careful monitoring of vital signs without any further serious reactions.","label":0,"label_text":"Not-Related"}
+{"text":"A case of Hodgkin's disease confined to the CNS, with cerebrospinal fluid negative for cytology, is described in an immunocompetent patient previously treated for hyperthyroidism with 131I.","label":0,"label_text":"Not-Related"}
+{"text":"Traditional neuroleptics have been the mainstay of treatment for agitated behavior in persons with dementia, but these agents have limited efficacy and are associated with high rates of adverse effects, including worsening of already poor cognitive functioning.","label":0,"label_text":"Not-Related"}
+{"text":"Desmopressin--a nontransfusional form of prevention of postextractive bleeding in some patients with von Willebrand's type I disease.","label":0,"label_text":"Not-Related"}
+{"text":"Unusual cause of methadone poisoning.","label":0,"label_text":"Not-Related"}
+{"text":"Pentostatin (2'-deoxycoformycin, DCF) was administered to 17 patients with a variety of lymphoid neoplasms, both T- and B-cell, that were refractory to conventional treatments.","label":0,"label_text":"Not-Related"}
+{"text":"The cause of these previously unreported side effects of niacin therapy is uncertain but may be related to prostaglandin-mediated vasodilatation, hyperalgesia of sensory nerve receptors, and potentiation of inflammation in the gingiva with referral of pain to the teeth.","label":1,"label_text":"Related"}
+{"text":"Nail-changes induced by penicillamine.","label":1,"label_text":"Related"}
+{"text":"Imaging and tissue biopsy revealed a diffuse large B-cell, non-Hodgkin's lymphoma.","label":0,"label_text":"Not-Related"}
+{"text":"During trimethadione treatment, impaired exocrine pancreatic function returned to normal in four of nine patients examined, and diabetes mellitus was well controlled by either diet therapy alone or oral hypoglycaemic agents in eight of 10 patients who did not need insulin before trimethadione treatment.","label":0,"label_text":"Not-Related"}
+{"text":"It is thought that the clinico-pathological features and chronology of this case bore the hallmarks of the so-called \"3-week sulphasalazine syndrome\", a rare, but often fatal, immunoallergic reaction to sulphasalazine.","label":1,"label_text":"Related"}
+{"text":"Thus, varenicline may not aid smoking cessation in patients undergoing treatment with amphetamine and amphetamine-like drugs.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: The pigmented cellular membranes observed on these silicone lenses were visually significant to each patient.","label":0,"label_text":"Not-Related"}
+{"text":"Two episodes were incident cases (no prior IBD); one episode was recurrent colitis or a nonincident case (flare of prior IBD).","label":0,"label_text":"Not-Related"}
+{"text":"Mitoxantrone appeared to have no cardiac toxicity.","label":0,"label_text":"Not-Related"}
+{"text":"Experience with five patients in whom impaired renal function developed early during amphotericin B therapy is reported.","label":1,"label_text":"Related"}
+{"text":"Three of 38 children given high-dose cytosine arabinoside therapy developed a previously undescribed complication.","label":0,"label_text":"Not-Related"}
+{"text":"Ophthalmological examination included testing of visual acuity, slit-lamp inspection, fundus inspection, fundus photography and kinetic perimetry.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a patient who developed 3 successive forms of joint manifestations: early HIV related arthralgias followed by drug related arthritis, and more recently by typical RA.","label":0,"label_text":"Not-Related"}
+{"text":"Sequential CT studies of 24 children with infantile spasms on ACTH therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Angiotensin-converting enzyme (ACE) inhibitors are widely used for controlling hypertension.","label":0,"label_text":"Not-Related"}
+{"text":"The chemotherapeutics, including vincristine, actinomycin D, and epirubicin in case 1 and vincristine and actinomycin D in case 2, were given before the hepatotoxicity developed.","label":1,"label_text":"Related"}
+{"text":"Scrotal ulceration induced by all-trans retinoic acid in a patient with acute promyelocytic leukemia.","label":1,"label_text":"Related"}
+{"text":"Intraocular ointment after small-incision cataract surgery causing chronic uveitis and secondary glaucoma.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To report a case of linear immunoglobulin (Ig) A bullous dermatosis (LABD) induced by gemcitabine.","label":1,"label_text":"Related"}
+{"text":"Only minor endocrine-metabolic changes were seen in this patient.","label":0,"label_text":"Not-Related"}
+{"text":"Diffuse cutaneous candidiasis in a dog.","label":0,"label_text":"Not-Related"}
+{"text":"We conclude that using hemoperfusion is an effective modality which may be used as an adjunct to supportive therapy when there is a need to increase the body clearance of chloramphenicol.","label":0,"label_text":"Not-Related"}
+{"text":"Captopril-induced lichen planus pemphigoides with pemphigus-like features.","label":1,"label_text":"Related"}
+{"text":"DISCUSSION: The main adverse effects of leflunomide consist of diarrhea, nausea, liver enzyme elevation, hypertension, alopecia, and allergic skin reactions.","label":1,"label_text":"Related"}
+{"text":"Successful treatment of molluscum contagiosum in the immunosuppressed adult with topical injection of streptococcal preparation OK-432.","label":0,"label_text":"Not-Related"}
+{"text":"Carboplatin hypersensitivity presenting as coronary vasospasm - a case report.","label":1,"label_text":"Related"}
+{"text":"Although the literature on the use of risperidone in elderly patients with dementia consists largely of uncontrolled trials, case reports, and chart reviews, it appears that this agent is effective for managing agitation in this population and does so with a low frequency of extrapyramidal symptoms (EPS).","label":1,"label_text":"Related"}
+{"text":"The most common clinical presentation is fever secondary to a central line infection.","label":0,"label_text":"Not-Related"}
+{"text":"Secondary spontaneous pneumothorax (SSP) is a rare complication of chemotherapy for pulmonary metastases and to the best of our knowledge, only 28 cases have been described, most of which occurred in patients with osteosarcoma or germ cell tumors.","label":0,"label_text":"Not-Related"}
+{"text":"It was highly suspected that finasteride was associated with the anterior subcapsular opacity on the lens, and the patient therefore discontinued use of finasteride.","label":1,"label_text":"Related"}
+{"text":"This case report describes a patient who was previously prescribed alendronate (Fosamax) and presented with postoperative hypophosphatemia and hypocalcemic tetany after bowel preparation with Fleet Phospho-Soda.","label":1,"label_text":"Related"}
+{"text":"This case provides an opportunity to discuss the difficulty of managing two potentially mortal conditions in which the treatment of pemphigus vulgaris may exacerbate the disseminated cryptococcal infection.","label":0,"label_text":"Not-Related"}
+{"text":"In view of the temporary symptomatic action and the seriousness of certain side-effects of desmopressin we recommend that desmopressin be used with caution in childhood enuresis.","label":0,"label_text":"Not-Related"}
+{"text":"A delay in standard emergency room management led to a delay in diagnosis and treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Although this combination agent has been associated with a hypersensitivity syndrome involving cutaneous skin eruptions, pediatric cases of TMP-SMX-induced hepatotoxicity are rare.","label":1,"label_text":"Related"}
+{"text":"Increased lash length, thickness, and pigmentation are well-documented side effects of prostaglandin analog glaucoma drops.","label":1,"label_text":"Related"}
+{"text":"The patient had ischemic brain lesions due to cardiopulmonary arrest at 39 weeks of corrected age.","label":0,"label_text":"Not-Related"}
+{"text":"Patients were started on topical tacrolimus ointment 0.03%, twice daily, which was tapered to the lowest possible therapeutic dose that maintained its antirejection efficacy.","label":0,"label_text":"Not-Related"}
+{"text":"Tamoxifen, the first clinically available SERM, was developed in 1966 and approved by the FDA (United States Food and Drug Administration) in 1978.","label":0,"label_text":"Not-Related"}
+{"text":"Pulmonary gold toxicity.","label":1,"label_text":"Related"}
+{"text":"The child had a fair outcome despite of the very acute course of the disease and the presence of a cervical sensory level which usually harbor a poor prognosis.","label":0,"label_text":"Not-Related"}
+{"text":"Ticlopidine withdrawal and treatment with antibiotics, transfusions, and G-CSF helped him to recover.","label":0,"label_text":"Not-Related"}
+{"text":"During 11 months of follow-up, arrhythmia did not recur.","label":0,"label_text":"Not-Related"}
+{"text":"Both the longitudinal melanonychia and the multiple skin cancers first appeared after approximately 6 months of hydroxyurea treatment.","label":1,"label_text":"Related"}
+{"text":"The current report demonstrates successful treatment, even in the setting of subsequent bone marrow transplantation and immunosuppression, using a combination of surgical resection and posaconazole therapy.","label":0,"label_text":"Not-Related"}
+{"text":"He also presented with skin and lip lesions considered to be chronic graft-versus host disease.","label":0,"label_text":"Not-Related"}
+{"text":"Here we describe a patient with Crohn's disease who developed a severe infliximab infusion reaction (IIR), complicated 1 day later by severe swelling of the forearm and hand ipsilateral to the site of infliximab infusion.","label":1,"label_text":"Related"}
+{"text":"Interference with smoking-cessation effects of varenicline after administration of immediate-release amphetamine-dextroamphetamine.","label":0,"label_text":"Not-Related"}
+{"text":"Severe acute encephalopathy following inadvertent intrathecal doxorubicin administration.","label":1,"label_text":"Related"}
+{"text":"To our knowledge, this is the first case of spontaneous remission of MTX-associated gastric LPD after discontinuation of MTX therapy.","label":1,"label_text":"Related"}
+{"text":"In all the patients, pellagra symptoms appeared during isoniazid therapy.","label":1,"label_text":"Related"}
+{"text":"Lamotrigine clearance increases throughout pregnancy, and maternal dose increases are often necessary to maintain therapeutic effect.","label":0,"label_text":"Not-Related"}
+{"text":"The present report describes four cases of this association in which tamoxifen had been administered to all of the patients.","label":0,"label_text":"Not-Related"}
+{"text":"We report three young Chinese male patients who underwent aortic valve replacement for severe aortic regurgitation of subacute onset, complicated by recurrent dehiscence of the aortic valve prosthesis, due to aortitis.","label":0,"label_text":"Not-Related"}
+{"text":"In one of these cases, the patient, a 47-year-old man, died 10 days later.","label":0,"label_text":"Not-Related"}
+{"text":"The authors suggest that fluoxetine-induced akathisia may be caused by serotonergically mediated inhibition of dopaminergic neurotransmission and that the pathophysiology of fluoxetine-induced akathisia and tricyclic antidepressant-induced \"jitteriness\" may be identical.","label":1,"label_text":"Related"}
+{"text":"Chemonucleolysis is a procedure for treatment of low back pain due to discogenic disease in which the drug chymopapain is injected into lumbar disks to produce chemical dissolution of the nucleus pulposus.","label":0,"label_text":"Not-Related"}
+{"text":"Embolic phenomena occurred in 10 (42%) of 24 cases.","label":0,"label_text":"Not-Related"}
+{"text":"The second bowl of decoction probably became more concentrated because of evaporation of water during continued boiling and contained a larger amount of 'maqianzi'.","label":0,"label_text":"Not-Related"}
+{"text":"Warfarin-associated bleeding generally is considered deleterious; however, in our patient it unmasked an early stage of colon cancer and thus may have saved the patient's life.","label":1,"label_text":"Related"}
+{"text":"Other primary causes of hepatotoxicity (alcohol consumption and viral hepatitis) were also verified in two cases, and in those patients biopsy findings revealed the presence of cirrhotic lesions in liver parenchyma.","label":0,"label_text":"Not-Related"}
+{"text":"Autoantibody assessment showed negative ANA, anti-dsDNA, anti-ENA, and ANCA, but positive granulocyte-bound antibodies (GBA) and neutrophil-specific (CD 16+)-bound antibodies (anti-NA).","label":0,"label_text":"Not-Related"}
+{"text":"Clinical, histological and serological studies--a further 10-year follow-up.","label":0,"label_text":"Not-Related"}
+{"text":"One patient required nursing home placement and a feeding gastrostomy as a result of the worsening parkinsonism during risperidone treatment, but was able to return home and have the gastrostomy removed after switching from risperidone to clozapine.","label":1,"label_text":"Related"}
+{"text":"To determine the effects of reversible medical castration on prostatic size in patients with benign prostatic hypertrophy (BPH), 3 patients with BPH were treated with a GnRH analogue, leuprolide, for six months at a dosage of .2ml (1 mg) s.c. daily.","label":0,"label_text":"Not-Related"}
+{"text":"There are many pertinent issues surrounding the treatment of bipolar disorder during pregnancy.","label":0,"label_text":"Not-Related"}
+{"text":"In addition to illustrating the potential diagnostic confusion with infection or lupus flare, this case is of interest in that the reaction developed suddenly despite the patient's uneventful use of the drug for over two years.","label":0,"label_text":"Not-Related"}
+{"text":"Colonic mucosal necrosis following administration of calcium polystryrene sulfonate (Kalimate) in a uremic patient.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: Although the mechanism is not clear, these cases add to several other reports concerning the sudden emergence of obsessive-compulsive symptoms and anxiety symptoms in children treated with atypical antipsychotics.","label":0,"label_text":"Not-Related"}
+{"text":"The case of a patient with infectious mononucleosis treated with cephalexin who later showed a rash is presented and the previous literature is reviewed.","label":1,"label_text":"Related"}
+{"text":"Two probands had borderline mutations; the rest were normal.","label":0,"label_text":"Not-Related"}
+{"text":"Clinicians must be aware of the delicate balance between the signs and symptoms of disease states and the effects of drugs.","label":0,"label_text":"Not-Related"}
+{"text":"Rapid resolution of topiramate-induced angle-closure glaucoma with methylprednisolone and mannitol.","label":1,"label_text":"Related"}
+{"text":"The Hybrizep method (which is available on the Japanese National Health system only for the diagnosis of septicemia) was a useful diagnostic approach for a patient on peritoneal dialysis who had peritonitis.","label":0,"label_text":"Not-Related"}
+{"text":"The literature describing the safety or efficacy of nesiritide in children is minimal, and we know of no data that describe the effects of a nesiritide overdose in adults or children.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: The synthetic corticosteroid methylprednisolone is used for the treatment of acute exacerbations of Crohn's disease, also in pregnancy.","label":0,"label_text":"Not-Related"}
+{"text":"CLB and N-CLB plasma level dosages and molecular analysis may be useful when a poor metabolic condition is suspected.","label":0,"label_text":"Not-Related"}
+{"text":"He developed VZV reinfection without skin lesions after family exposure and influenza A was community-acquired.","label":0,"label_text":"Not-Related"}
+{"text":"Two elderly women suffered an acute deterioration of renal function after treatment with cefoxitin sodium.","label":1,"label_text":"Related"}
+{"text":"This is the first report of UFT-induced scleroderma-like reaction.","label":1,"label_text":"Related"}
+{"text":"For such tumors to be successfully removed, at least part of the parotid duct must be excised as well.","label":0,"label_text":"Not-Related"}
+{"text":"Staphylococcus aureus is one of the main causes of bacteriaemia.","label":0,"label_text":"Not-Related"}
+{"text":"If suspected, prompt medical assessment should be arranged, including serum glucose and cortisol measurement.","label":0,"label_text":"Not-Related"}
+{"text":"The toxic effects of methotrexate included elevated liver transaminases (3\/4), nausea (2\/4), abdominal pain (2\/4), bone pain (2\/4), mild neutropenia (1\/4), and mild pruritus (1\/4).","label":1,"label_text":"Related"}
+{"text":"METHODS: We describe the case of a 41-year-old male with HIV who received protease inhibitor medication and had neurologic deficits rapidly develop.","label":0,"label_text":"Not-Related"}
+{"text":"Diabetes mellitus type 1 in five military aviators: flying with insulin.","label":0,"label_text":"Not-Related"}
+{"text":"Eleven days after initiation of therapy with amiodarone, the patient experienced syncope and was noted to have recurrent episodes of polymorphous ventricular tachycardia.","label":1,"label_text":"Related"}
+{"text":"A 68-year-old female patient with advanced ovarian carcinoma collapsed whilst receiving a carboplatin and cyclophosphamide infusion.","label":1,"label_text":"Related"}
+{"text":"Further analysis of these cases suggests that the development of the ectopic ACTH syndrome may reflect changes in cell populations within the tumor and\/or alterations in tumor behavior with time and perhaps with the effects of drug therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Tumor resection was performed, with posterolateral fusion and spinal instrumentation.","label":0,"label_text":"Not-Related"}
+{"text":"There was a good correlation between the total dose of ACTH and the percentage decrease of brain parenchyma.","label":0,"label_text":"Not-Related"}
+{"text":"Transthoracic echocardiography showed a mass in the LA.","label":0,"label_text":"Not-Related"}
+{"text":"He had an immediate hypersensitivity reaction during the initiation of the MTX infusion with diffuse urticaria, facial swelling, cough, and chest tightness.","label":1,"label_text":"Related"}
+{"text":"The difference between infliximab and etanercept in viral reactivation may be linked to the pharmacologic difference of each medication.","label":0,"label_text":"Not-Related"}
+{"text":"Reserpine was administered specifically for hypertension in 91.3 percent of patients; 35.5 per cent of patients received the drug by intramuscular (IM) injection.","label":0,"label_text":"Not-Related"}
+{"text":"This organism has rapidly spread through many countries.","label":0,"label_text":"Not-Related"}
+{"text":"Hypoglycaemic coma recurred.","label":0,"label_text":"Not-Related"}
+{"text":"Remission was confirmed objectively with pure-tone audiometry.","label":0,"label_text":"Not-Related"}
+{"text":"There was complete radiological and clinical resolution of the abscess on prolonged treatment with amphotericin alone.","label":0,"label_text":"Not-Related"}
+{"text":"Further investigation excluded malignancy.","label":0,"label_text":"Not-Related"}
+{"text":"Previously noted abnormal signal intensities have nearly disappreared on follow-up MRI obtained on the 22nd day after the first seizure.","label":0,"label_text":"Not-Related"}
+{"text":"Nocardiosis in a patient with primary anti-phospholipid syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Four cases of fat embolism are described in infants receiving prolonged intravenous infusion of fat (Intralipid 20%).","label":1,"label_text":"Related"}
+{"text":"Thymic hyperplasia can occur after cytotoxic therapy for various malignancies.","label":0,"label_text":"Not-Related"}
+{"text":"We describe 2 patients with prior amputation who experienced phantom limb pain (PLP) after receiving paclitaxel therapy.","label":1,"label_text":"Related"}
+{"text":"Fungal infections are rare but represent serious complications following organ transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"The literature is devoid of reports indicating that a reduction in the dosage or discontinuation of antidepressants of any chemical class produces symptoms of major depression within 2-4 d.","label":0,"label_text":"Not-Related"}
+{"text":"Four months after treatment was initiated, there was no evidence of recurrent fungal keratitis or endophthalmitis.","label":0,"label_text":"Not-Related"}
+{"text":"The median duration of subsequent remission was only 13 weeks, but six out of eight children receiving a second course of the drug combination achieved a further remission.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: We describe the ophthalmic features and clinical course of two cases of acute syphilitic posterior placoid chorioretinitis (ASPPC) that developed after intravitreal triamcinolone acetonide (IVTA) injection.","label":1,"label_text":"Related"}
+{"text":"However, one patient exhibited severe hypersensitivity reactions including cardiac arrest and apnea, and another four patients developed eruptions, hypotension, and tachycardia soon after administration of CBDCA.","label":1,"label_text":"Related"}
+{"text":"She was placed on adjuvant Adriamycin (doxorubicin) chemotherapy, but 6 months later died of Adriamycin toxicity.","label":1,"label_text":"Related"}
+{"text":"RESULTS: The loss of subcutaneous tissue in the injection areas was demonstrated and measured by high-frequency ultrasound.","label":0,"label_text":"Not-Related"}
+{"text":"Transcutaneous computed tomography guided core needle biopsy established the diagnosis of pelvic actinomycosis obviating immediate surgical intervention.","label":0,"label_text":"Not-Related"}
+{"text":"Case no. 1 showed features of photoallergy such as 1-month incubation period, decreased MED to UVA, strong positive photopatch test result, cross reaction to chlorpromazine, and angry back phenomenon found in allergic contact dermatitis.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of antibiotic-associated pseudomembranous colitis with metronidazole.","label":0,"label_text":"Not-Related"}
+{"text":"On the 4th day, the pattern of VWFMs was completely normalized and appeared to persist until the 10th day.","label":0,"label_text":"Not-Related"}
+{"text":"We present a case with important pharmacogenetic and pharmacokinetic aspects of antiretroviral therapy in a patient with high efavirenz concentrations, severe CNS side-effects and low lopinavir concentrations.","label":0,"label_text":"Not-Related"}
+{"text":"Reciprocal chromosomal translocations involving the MLL gene at chromosome region 11q23 are recurring cytogenetic abnormalities in both de novo and therapy-related acute myeloid leukemia (AML) and in acute lymphoblastic leukemia.","label":0,"label_text":"Not-Related"}
+{"text":"Amphotericin B (AmB) is effective, but its use is limited by toxicity: renal impairment, anaemia, fever, malaise, and hypokalaemia are common.","label":1,"label_text":"Related"}
+{"text":"Hand-made articulating spacers for infected total knee arthroplasty: a technical note.","label":0,"label_text":"Not-Related"}
+{"text":"Opioid drugs should not be administered for several hours before a diagnostic hepatobiliary scan.","label":0,"label_text":"Not-Related"}
+{"text":"Adenomyosis is an important cause of menorrhagia.","label":0,"label_text":"Not-Related"}
+{"text":"To our knowledge, this is the first reported case in Thailand.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a case of disseminated muscular cysticercosis followed by myositis (fever, diffuse myalgia, weakness of the lower limbs, and inflammatory reaction around dying cysticerci) induced by praziquantel therapy, an event not described previously.","label":1,"label_text":"Related"}
+{"text":"One such case that was managed conservatively with success is reported.","label":0,"label_text":"Not-Related"}
+{"text":"Total resection revealed that the lesions were composed entirely of fatty tissue.","label":0,"label_text":"Not-Related"}
+{"text":"Both of these findings are due to the unique effects of rifampicin on steroid metabolism.","label":0,"label_text":"Not-Related"}
+{"text":"Both recovered after withdrawal of the drug.","label":0,"label_text":"Not-Related"}
+{"text":"Four years after 2-CdA treatment, the patient has psoriasis on only 1% of his body surface area.","label":0,"label_text":"Not-Related"}
+{"text":"Prolonged severe cholestasis induced by oxacillin derivatives.","label":1,"label_text":"Related"}
+{"text":"Seizure with hyponatremia in a child prescribed desmopressin for nocturnal enuresis.","label":1,"label_text":"Related"}
+{"text":"Usefulness of antiplatelet drugs in the management of heparin-associated thrombocytopenia and thrombosis.","label":1,"label_text":"Related"}
+{"text":"Two months later, at a follow-up visit, her serum cesium level was 1800 microg\/dl, and her QTc interval was 494 msec.","label":0,"label_text":"Not-Related"}
+{"text":"The physiological complexities of deep-diving research are reviewed, as well as the neuropsychiatric symptoms of the high pressure nervous syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"He had been taking trimethoprim-sulfamethoxazole for approximately eight days when he revisited his family physician, complaining of headaches, dizziness, difficulty with speech, weakness, and itching on the trunk of his body and legs, where a maculopapular rash was noted.","label":1,"label_text":"Related"}
+{"text":"Rare infusion reactions that resulted in the cessation of therapy have been described after cetuximab administration.","label":0,"label_text":"Not-Related"}
+{"text":"The hematomas resolved in the other patient, who delivered at term.","label":0,"label_text":"Not-Related"}
+{"text":"Histologic examination of the neoplasm was consistent with a high-grade pancreatic exocrine adenocarcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"Guidelines for handling common scenarios in PD patients will be illustrated by 10 case histories.","label":0,"label_text":"Not-Related"}
+{"text":"Here, we describe a case of Vogt-Koyanagi-Harada disease occurring 4 months after the start of interferon alpha treatment, probably induced by the immunomodulatory effects of interferon.","label":1,"label_text":"Related"}
+{"text":"The only recent change in their treatment was the introduction or increased dosage of zonisamide.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Most of the new fillers used for soft tissue augmentation in aesthetic dermatology are considered well tolerated, but very little data are available on their long-term tolerability, especially in patients receiving immunomodulatory therapy.","label":0,"label_text":"Not-Related"}
+{"text":"In all cases the presentation was atypical, and in two cases the course was protracted, leading to some visual loss from corneal scarring and opacification.","label":0,"label_text":"Not-Related"}
+{"text":"Every year they receive dilated fundoscopic eye examination.","label":0,"label_text":"Not-Related"}
+{"text":"We present two children with acute lymphocytic leukemia who developed leukoencephalopathy following administration of a combination of intravenous ara = C and methotrexate during the consolidation phase of chemotherapy.","label":1,"label_text":"Related"}
+{"text":"Phase I and pharmacokinetic study of a novel mitomycin C analog KW-2149.","label":0,"label_text":"Not-Related"}
+{"text":"The drug was discontinued and papular lesions gradually disappeared.","label":0,"label_text":"Not-Related"}
+{"text":"Oral chemical burns caused by self-medication in a child: case report.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: In selected patients, a continuous infusion of haloperidol may be a useful alternative for control of agitation and delirium.","label":0,"label_text":"Not-Related"}
+{"text":"In case no. 2, the pathogenic mechanism seemed to be persistent light reaction preceded by systemic photoallergy, as he had taken mequitazine for 6 months, and there were strong positive photopatch test results with immediate erythema reaction, cross-reaction to promethazine, decreased MED to both UVA and UVB, and persistence of the photosensitivity over a 3-year follow-up period after discontinuation of the mequitazine.","label":1,"label_text":"Related"}
+{"text":"Glaucoma from topical corticosteroids to the eyelids.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: A retrospective report of the first case of gemcitabine-related HUS, in a patient with metastatic pancreatic adenocarcinoma, treated with a variety of standard therapies in addition to rituximab is presented.","label":1,"label_text":"Related"}
+{"text":"We describe a 37-year-old woman who was receiving temozolomide for treatment of metastatic melanoma.","label":0,"label_text":"Not-Related"}
+{"text":"These data indicate that lithium may limit the therapeutic efficacy of reserpine in tardive dyskinesia.","label":0,"label_text":"Not-Related"}
+{"text":"PURPOSE: To report a case of angiographically documented cystoid macula edema occurring after switching a pseudophakic patient from latanoprost to bimatoprost.","label":1,"label_text":"Related"}
+{"text":"We introduce a case of a sixty years old woman with several previous episodes of rhinitis, conjunctivitis and perspiration immediately after the administration of salmon calcitonin with nasal spray or intramuscular administration (Calsynar).","label":1,"label_text":"Related"}
+{"text":"In the last decades there have been reports describing a transient form of constrictive pericarditis, which resolves without surgical therapy.","label":0,"label_text":"Not-Related"}
+{"text":"The diagnosis thrombocytopenia caused by common drugs can be difficult, requiring persistent, explicit questions.","label":0,"label_text":"Not-Related"}
+{"text":"A 22-year-old black man developed fever, chills, fatigue, night sweats, tender lymphadenopathy, and a generalized, pruritic, macular eruption 3 weeks after starting minocycline therapy for acne.","label":1,"label_text":"Related"}
+{"text":"OBJECTIVE: We describe the prolonged clinical benefit of murine chimeric antitumor necrosis factor (TNF)-alpha monoclonal antibody, infliximab, on pediatric patients with Crohn's disease and ileal pouch anal anastomosis (IPAA).","label":0,"label_text":"Not-Related"}
+{"text":"The present report suggests that clarithromycin coadministration induces increased plasma carbamazepine concentrations, which may result in carbamazepine toxicity.","label":1,"label_text":"Related"}
+{"text":"Rechallenge with chlorothiazide while on a sodium- and potassium-controlled balanced diet resulted in a decrease in serum sodium concentration (136 to 124 mEq\/L) and plasma osmolality (283 to 261 mOsm\/kg) within 18 hours.","label":0,"label_text":"Not-Related"}
+{"text":"The association of the use of certain androgenic steroids with hepatic neoplasms histologically resembling hepatocarcinomas, but characterized by lack of metastases and apparent reversibility, suggests the desirability of a new nomenclature for these hepatocellular lesions.","label":0,"label_text":"Not-Related"}
+{"text":"Periodic gynecologic assessment should be part of the follow-up of all women on long-term tamoxifen therapy.","label":0,"label_text":"Not-Related"}
+{"text":"We reviewed the records of 3 patients with lymphoproliferative disorders who experienced acute coronary syndromes associated with their initial infusion of rituximab.","label":1,"label_text":"Related"}
+{"text":"She underwent a thymectomy at 40 years of age to treat myasthenia gravis.","label":0,"label_text":"Not-Related"}
+{"text":"Traumatic late flap dehiscence and Enterobacter keratitis following LASIK.","label":1,"label_text":"Related"}
+{"text":"CASE: We report a 17-year old JRA patient with primary ovarian diffuse large B-cell non-Hodgkin's lymphoma (NHL).","label":0,"label_text":"Not-Related"}
+{"text":"Three possibilities existed to account for this outbreak: the positive cultures represented isolated events; there was one isolated event and a common source; or, all events were due to a common source.","label":0,"label_text":"Not-Related"}
+{"text":"Painful erosion of psoriatic plaques is a less common sign of methotrexate toxicity that may precede evidence of bone marrow suppression.","label":1,"label_text":"Related"}
+{"text":"Reported herein are two NMS patients with schizophrenia who were found to possess a CYP2D6 gene deletion allele (CYP2D6*5).","label":0,"label_text":"Not-Related"}
+{"text":"Cutaneous sarcoidosis during interferon alfa and ribavirin treatment of hepatitis C virus infection: two cases.","label":1,"label_text":"Related"}
+{"text":"Intrahepatic cholestasis and cutaneous bullae associated with glibenclamide therapy.","label":1,"label_text":"Related"}
+{"text":"Myoclonus seen in the abdominal wall was segmental and considered to be of spinal origin.","label":0,"label_text":"Not-Related"}
+{"text":"We describe the case of a 56-year-old man who had high aminotransferase levels and anti-hepatitis C virus (HCV) antibodies.","label":0,"label_text":"Not-Related"}
+{"text":"Umbilical artery catheterization is often performed in critically ill neonates.","label":0,"label_text":"Not-Related"}
+{"text":"Several such HBV reactivations were reported after combined rituximab and multiagent chemotherapy for B-cell lymphomas.","label":1,"label_text":"Related"}
+{"text":"The finding of decreased lymphocyte Mg and potassium contents proved the existence of cellular Mg depletion associated with normal serum Mg levels in five patients and with hypomagnesemia in the other two.","label":0,"label_text":"Not-Related"}
+{"text":"The use of 5-fluorouracil given in the usual manner appears to have been a failure.","label":0,"label_text":"Not-Related"}
+{"text":"We hypothesize that caffeine toxicity injured the muscle cells, which were fragile due to the potassium depletion induced by the coexisting hyponatremia, to result in unusually severe rhabdomyolysis.","label":1,"label_text":"Related"}
+{"text":"Nitrates occur in high concentrations in some food and water.","label":0,"label_text":"Not-Related"}
+{"text":"A case of Sweet's syndrome following septic pulmonary emboli after high-dose chemotherapy for advanced testicular cancer.","label":0,"label_text":"Not-Related"}
+{"text":"Therapy to relieve the compression was disappointing.","label":0,"label_text":"Not-Related"}
+{"text":"Patient 1 also received a nine-month course of combined therapy with melphalan, procarbazine, and prednisone.","label":0,"label_text":"Not-Related"}
+{"text":"The uveitis is almost always interior, begins unilaterally and progresses to involve both eyes.","label":0,"label_text":"Not-Related"}
+{"text":"These neurological symptoms should be added to a growing list of important complications of DIHS\/DRESS because of the high mortality rate associated with them.","label":0,"label_text":"Not-Related"}
+{"text":"One week after beginning of HAART, tacrolimus was discontinued during 18 days due Ritonavir interaction.","label":0,"label_text":"Not-Related"}
+{"text":"Apparent cyclophosphamide (cytoxan) embryopathy: a distinct phenotype?","label":1,"label_text":"Related"}
+{"text":"The organism was unusual in its resistance to chloramphenicol and ampicillin; however, it was sensitive to a sulfonamide and trimethoprim.","label":0,"label_text":"Not-Related"}
+{"text":"Test results from a skin biopsy specimen were consistent with a drug reaction.","label":0,"label_text":"Not-Related"}
+{"text":"The occurrence of acute hepatitis is best known for ketoconazole.","label":1,"label_text":"Related"}
+{"text":"A diagnosis of tuberculous uveitis was established; the patient was treated with rifampin, isoniazid pyrazinamide, and ethambutol and etanercept was stopped.","label":0,"label_text":"Not-Related"}
+{"text":"It is stressed that ethambutol may act as a trigger factor to the toxic effects of Rifampicin.","label":0,"label_text":"Not-Related"}
+{"text":"The clinical features are described on the basis of four cases.","label":0,"label_text":"Not-Related"}
+{"text":"Biopsies from skin of normal appearance from 18 patients treated with carbamazepine and diphenylhydantoin were investigated by a direct immunofluorescence technique.","label":0,"label_text":"Not-Related"}
+{"text":"During the follow-up period of two months, there was transiently decreased MED to UVB, which became normalized after 1 month treatment with cyclophosphamide.","label":0,"label_text":"Not-Related"}
+{"text":"In 2 of the 3 cases the patients were also taking lithium carbonate and beta-blockers, both of which could have contributed to the incontinence.","label":1,"label_text":"Related"}
+{"text":"Case 2, a 29-year-old woman, developed bilateral optic neuritis combined with numbness of the lower extremities as well as bowel and bladder dysfunction after a 22-month use of recombinant interferon alpha-2b for chronic myelogenous leukemia.","label":1,"label_text":"Related"}
+{"text":"There is a disagreement regarding imaging studies.","label":0,"label_text":"Not-Related"}
+{"text":"Two days later the patient developed visual hallucinations, ataxia, confusion and memory loss along with focal myoclonus, nausea and vomiting.","label":0,"label_text":"Not-Related"}
+{"text":"The severity of cutaneous and hematologic toxicity experienced by our patient has rarely been reported.","label":0,"label_text":"Not-Related"}
+{"text":"It is suggested that the long-term use of androgenic-anabolic steroids is the fourth cause of HAS, the majority of cases still being of unknown aetiology.","label":0,"label_text":"Not-Related"}
+{"text":"Intravenous sodium bicarbonate and furosemide, and intrarectal calcium polystyrenesulfonate were administered to correct the acidosis and promote potassium secretion.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To describe two cases of rhabdomyolysis in patients taking lovastatin that were precipitated by the use of the newer macrolide antibiotics clarithromycin and azithromycin.","label":1,"label_text":"Related"}
+{"text":"In this report, we will describe the first case of obsessive-compulsive behaviour following oral corticosteroid treatment in a 75-year old adult male patient with pulmonary disease, but without previous psychiatric symptoms or organic brain disorder.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of a young woman with SLE and thrombocytopenia, who developed severe perspiration, headache, and seizure after receiving cyclosporine.","label":1,"label_text":"Related"}
+{"text":"Timely diagnosis and management is crucial to maintain good structural and visual outcomes.","label":0,"label_text":"Not-Related"}
+{"text":"We therefore assume that the risk of severe neurological complications is underestimated.","label":0,"label_text":"Not-Related"}
+{"text":"The patients, a 4-year-old with microcephaly and severe retardation, a 1-year-old with cerebral dysgenesis, and a 5-year-old with spastic quadriplegia and mild retardation, all had seizures unresponsive to multiple anticonvulsant combinations.","label":0,"label_text":"Not-Related"}
+{"text":"Blood lead level was > 200 microg\/dl.","label":0,"label_text":"Not-Related"}
+{"text":"In December 1998, he applied to our clinic for a follow-up examination.","label":0,"label_text":"Not-Related"}
+{"text":"METHOD: Case analysis of a poly-drug overdose (venlafaxine, topiramate, divalproex sodium, risperidone, and carbamazepine) presenting with mixed SS\/NMS features and whose clinical management suggests a practical algorithm for treatment of undifferentiated SS\/NMS in critical care settings.","label":1,"label_text":"Related"}
+{"text":"Interstitial granulomatous dermatitis is most commonly associated with rheumatoid arthritis (RA) but may be induced by medications as well.","label":0,"label_text":"Not-Related"}
+{"text":"Physical examination showed slate gray discoloration of her skin, most pronounced on the face and neck.","label":0,"label_text":"Not-Related"}
+{"text":"We present a case of ethylenediamine-induced delayed hypersensitivity reaction in a 46-year-old woman who received parenteral aminophylline for an acute asthma exacerbation.","label":1,"label_text":"Related"}
+{"text":"Multicentric hepatocellular carcinoma following phosphate diethylstilbestrol therapy for prostatic cancer.","label":1,"label_text":"Related"}
+{"text":"This study reports the results of a retrospective review of the case records of 28 seriously ill patients who received intravenous cimetidine (generally 300 mg q8h) for the treatment of gastric discomfort and\/or hemorrhage or for prophylaxis against stress-induced ulcers.","label":0,"label_text":"Not-Related"}
+{"text":"Investigation confirmed the diagnosis of rhabdomyolysis, and discontinuation of colchicine resulted in resolution of clinical and biochemical features of rhabdomylysis.","label":1,"label_text":"Related"}
+{"text":"Thyroid function should be assessed before and during alpha interferon therapy in patients with chronic hepatitis C.","label":0,"label_text":"Not-Related"}
+{"text":"We present a patient who developed life-threatening Met-Hgb from the local anesthesia required during percutaneous endoscopic gastrostomy tube placement.","label":0,"label_text":"Not-Related"}
+{"text":"Progression of chronic myeloid leukemia to blast crisis during treatment with imatinib mesylate.","label":1,"label_text":"Related"}
+{"text":"We present two cases of nitrofurantoin-induced pulmonary toxicity in which the initial HRCT showed a widespread reticular pattern and associated distortion of the lung parenchyma, thought to represent established fibrosis.","label":1,"label_text":"Related"}
+{"text":"Persistent ashen-gray maculae and freckles induced by long-term PUVA treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Baclofen withdrawal syndrome resulting from underdosing of oral baclofen should be considered as a potential source of prolonged fever in the intensive care unit.","label":1,"label_text":"Related"}
+{"text":"A case of tuberculous peritonitis complicating continuous ambulatory peritoneal dialysis (CAPD) in a 37-year-old man who presented with fever, abdominal pain, and a malfunctioning Tenckhoff catheter is reported.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of a lung cancer patient with bronquiloalveolar carcinoma (BAC) presenting with BOOP after chemotherapy with docetaxel and gemcitabine producing severe respiratory insufficiency, and simulating a progression of the tumor.","label":1,"label_text":"Related"}
+{"text":"As the number of cases of refractive surgery in Australia increases, optometrists will encounter this condition more frequently.","label":0,"label_text":"Not-Related"}
+{"text":"Diagnosed with diabetic ketoacidosis, he was given insulin and saline with discontinuation of all antipsychotics.","label":0,"label_text":"Not-Related"}
+{"text":"We encountered four patients who developed Acanthamoeba keratitis while wearing contact lenses that had been stored in homemade saline.","label":0,"label_text":"Not-Related"}
+{"text":"A 44-year-old woman with a previous diagnosis of multiple sclerosis presented with panuveitis and retinal perivasculitis.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a case of significant and potentially toxic absorption of oral vancomycin in a peripheral blood stem cell transplant patient with grade IV graft-versus-host disease (GVHD) of the GI tract.","label":0,"label_text":"Not-Related"}
+{"text":"PURPOSE: To report a case of herpes zoster ophthalmicus reactivation following laser in situ keratomileusis (LASIK) for myopia.","label":0,"label_text":"Not-Related"}
+{"text":"A bone marrow aspirate and biopsy confirmed the diagnosis of AA and suggested the existence of an immunological reaction at the level of marrow.","label":0,"label_text":"Not-Related"}
+{"text":"Rifampin can be associated with severe adverse effects such as hepatitis, acute renal failure, hemolytic anemia, and thrombocytopenia.","label":1,"label_text":"Related"}
+{"text":"We describe a case of significant elevation of serum transaminases in a patient treated with 6-TG for a flare of Crohn's disease.","label":1,"label_text":"Related"}
+{"text":"Methylphenidate (Ritalin)-associated cataract and glaucoma.","label":1,"label_text":"Related"}
+{"text":"This paper reports on a 6.9-year-old autistic male who developed repeated episodes of acute dystonic reactions associated with pimozide administration at the doses of 0.096 mg\/kg\/day and 0.032 mg\/kg\/day and 32 hours following pimozide withdrawal, as well as during subsequent thioridazine administration.","label":1,"label_text":"Related"}
+{"text":"Dyskinesias induced by subthalamotomy in Parkinson's disease are unresponsive to amantadine.","label":0,"label_text":"Not-Related"}
+{"text":"A unique case of transient, profound paralysis after epidural steroid injection is reported here.","label":0,"label_text":"Not-Related"}
+{"text":"The proband had no detectable DPD activity.","label":0,"label_text":"Not-Related"}
+{"text":"The amounts of total brompheniramine, dextromethorphan, and pseudoephedrine remaining in the baby bottle were 1.4 mg, 9.4 mg, and 40 mg, respectively.","label":0,"label_text":"Not-Related"}
+{"text":"We present a case report of a patient with alveolar hydatid disease, whose treatment with mebendazole was brief due to side effects of alopecia and granulocytopenia; and review the features of this disease which, with increasing international migration, may be encountered more frequently in Australia.","label":1,"label_text":"Related"}
+{"text":"PURPOSE: To report spectral domain optical coherence tomography (OCT) and angiographic findings in exudative retinal detachment complicating central serous chorioretinopathy.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: A 68-year-old man developed intense conjunctival hyperemia and cystoid macula edema after switching from latanoprost to bimatoprost 9 months after cataract surgery in an eye at low-risk for this cystoid macular edema.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND: The number of leishmaniasis cases associated with immunosuppression has increased regularly over the past 20 years.","label":0,"label_text":"Not-Related"}
+{"text":"Temozolomide is a relatively new chemotherapeutic agent frequently associated with selective CD4+ T-lymphocytopenia.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: ECT was an effective local treatment in the majority of nodules treated.","label":0,"label_text":"Not-Related"}
+{"text":"Exposure to mercury vapour produced in operating rooms is the main concern for dentists.","label":0,"label_text":"Not-Related"}
+{"text":"Detection and treatment of Strongyloides hyperinfection syndrome following lung transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"A 7-year-old boy with T cell acute lymphoblastic leukemia developed disseminated hyalohyphomycosis due to Fusarium solani.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was left untreated and died 5 months after this diagnosis was made, of a second malignancy.","label":0,"label_text":"Not-Related"}
+{"text":"Generalized argyria after habitual use of AgNO3.","label":1,"label_text":"Related"}
+{"text":"A 27-year-old Caucasian woman with end-stage Crohn's disease was hospitalized with an upper extremity thrombosis.","label":0,"label_text":"Not-Related"}
+{"text":"She recovered spontaneously within several days, making transplantation unnecessary.","label":0,"label_text":"Not-Related"}
+{"text":"The renal insufficiency of three patients and the timing of the seizures implicate accumulation of ofloxacin as a contributing factor.","label":1,"label_text":"Related"}
+{"text":"We report here the case of an immunocompetent 3(1\/2)-year-old girl who developed encephalitis and herpes zoster opthalmicus 20 months after her immunization with varicella-zoster virus vaccine.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a patient in whom this was the primary manifestation of drug hypersensitivity.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVES: A delayed stroke-like leukoencephalopathy has been observed in patients receiving methotrexate (MTX) for childhood leukemia.","label":1,"label_text":"Related"}
+{"text":"PURPOSE: Interface inflammation is a common complication of laser in situ keratomileusis (LASIK).","label":0,"label_text":"Not-Related"}
+{"text":"Pathogenesis of methotrexate-induced papular eruption in psoriasis may involve immune mechanisms other than those of methotrexate-induced cutaneous vasculitis in collagen vascular disease.","label":1,"label_text":"Related"}
+{"text":"Posthypoglycemic hyperglycemia (rebound hyperglycemia) after overdosing of insulin was diagnosed in 6 cats with diabetes mellitus.","label":1,"label_text":"Related"}
+{"text":"This symptom gradually abated within a week and when the dosage of milnacipran was increased to 100 mg day(-1) at 2 months, no further piloerection occurred.","label":0,"label_text":"Not-Related"}
+{"text":"Acute pancreatitis associated with high-concentration lipid emulsion during total parenteral nutrition therapy for Crohn's disease.","label":0,"label_text":"Not-Related"}
+{"text":"Immune reconstitution inflammatory syndrome (IRIS) is a recently described entity in which severely immunodepressed HIV patients, after being started on HAART, develop inflammatory reactions to several pathogens.","label":0,"label_text":"Not-Related"}
+{"text":"Gemcitabine-related radiation recall preferentially involves internal tissue and organs.","label":1,"label_text":"Related"}
+{"text":"The present report illustrates a rare case of refractory akathisia after interferon-alpha treatment and also that levodopa treatment would be theoretically and practically useful in reducing the neurotoxicity associated with interferon-alpha.","label":1,"label_text":"Related"}
+{"text":"Although the source and timing of HBV exposure remain unclear, the potential for severe hepatitis B infection following bone marrow transplant warrants caution.","label":0,"label_text":"Not-Related"}
+{"text":"Trimethoprim-sulfamethoxazole-induced aseptic meningitis.","label":1,"label_text":"Related"}
+{"text":"A child in whom a phenobarbital hypersensitivity drug reaction developed which consisted of fever, a pruritic desquamating erythrodermic rash, alopecia, icterus, protein-losing enteropathy, myositis, and nephritis, is described.","label":1,"label_text":"Related"}
+{"text":"METHODS: Double-blind, placebo-controlled titrated oral challenges with pancreatic enzymes resulted in definite vomiting within 1 to 1.5 hours after challenges with Viokase and Pancrease MT 16, but not with placebo.","label":1,"label_text":"Related"}
+{"text":"We believe serum triglyceride levels should be monitored in patients who have other cardiac risk factors and are receiving clozapine.","label":0,"label_text":"Not-Related"}
+{"text":"Myelodysplasia syndrome (MDS) presenting as spontaneous gingival hemorrhage is described.","label":0,"label_text":"Not-Related"}
+{"text":"The mechanisms of methotrexate toxicity remain unclear, and no effective treatment exists to prevent its occurrence.","label":0,"label_text":"Not-Related"}
+{"text":"His fever resolved, but he developed symptoms consistent with those of chloroquine toxicity.","label":1,"label_text":"Related"}
+{"text":"Relapse in the external auditory canal of acute promyelocytic leukemia after treatment with all-trans retinoic acid.","label":1,"label_text":"Related"}
+{"text":"For therapeutic drug monitoring (TDM), blood samples were collected on day 1.","label":0,"label_text":"Not-Related"}
+{"text":"Hence, abrupt discontinuation of antimuscarinics or anticholinergics with high antimuscarinic properties in patients receiving long-term acetylcholinesterase inhibition therapy may be associated with a reduction of seizure threshold.","label":0,"label_text":"Not-Related"}
+{"text":"Monoclonal gammopathy and subsequent multiple myeloma in a patient on chronic diphenylhydantoin therapy.","label":1,"label_text":"Related"}
+{"text":"A 69-year-old woman developed Cushing's syndrome after long-term use of Sinatren, an Indonesian over the-counter drug, which was pharmacologically analysed three times before the correct content was discovered.","label":0,"label_text":"Not-Related"}
+{"text":"We present the first case of GVO-complicated pyogenic portosplenic vein thrombosis which led to persistent Klebsiella pneumoniae septicemia.","label":0,"label_text":"Not-Related"}
+{"text":"METHOD: We describe three case-reports concerning haematological adverse effects of quetiapine.","label":1,"label_text":"Related"}
+{"text":"TB should always be considered as a possible diagnosis when treating febrile immunocompromised patients.","label":0,"label_text":"Not-Related"}
+{"text":"Although it is generally well tolerated, liver toxicity has been recognised as a complication of long-term use.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: The most rational approach to treating NMS entails a hierarchy of interventions determined by the severity and progression of symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"Oral and topical forms of psoralen-containing drugs are routinely used in medicine.","label":0,"label_text":"Not-Related"}
+{"text":"The first case concerns a 70-year-old man who developed severe aplastic anemia 7 weeks after treatment with 500 mg of ticlopidine daily.","label":1,"label_text":"Related"}
+{"text":"He is in remission of AML and tuberculosis.","label":0,"label_text":"Not-Related"}
+{"text":"The majority of the induced lesions is in the distal ileum, sigmoid colon, or rectum.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients were found to have a positive ANA at low titers, 1 of whom had histopathologic evidence of stratum malgiphian necrosis with perivascular lymphocytic infiltration on skin biopsy.","label":0,"label_text":"Not-Related"}
+{"text":"We report an unusual case of massive fluoxetine ingestion resulting in neurological and cardiovascular toxicity resulting in death.","label":1,"label_text":"Related"}
+{"text":"Adenocarcinoma of the pancreas developed in a young man who was a 10-year survivor of acute myeloblastic leukemia (AML).","label":0,"label_text":"Not-Related"}
+{"text":"Treatment was stopped after 2 weeks.","label":0,"label_text":"Not-Related"}
+{"text":"The epivodes of NMS occured under treatment with clozapine, risperidone, and amisulpride.","label":1,"label_text":"Related"}
+{"text":"Cutaneous necrosis after injection of polyethylene glycol-modified interferon alfa.","label":1,"label_text":"Related"}
+{"text":"Infliximab and its serious adverse effects are discussed, and other cases of osteomyelitis with infliximab use are also reviewed.","label":1,"label_text":"Related"}
+{"text":"Laboratory tests revealed cyclosporine nephrotoxicity, cytomegalovirus infection, and prediabetes.","label":0,"label_text":"Not-Related"}
+{"text":"Cases include typical and unusual presentations of the syndrome, and commonly encountered problems and pitfalls of therapy.","label":0,"label_text":"Not-Related"}
+{"text":"He was treated and monitored over the subsequent several months.","label":0,"label_text":"Not-Related"}
+{"text":"In three patients, involuntary movements emerged during the course of treatment and in the others only after discontinuation of the drug.","label":0,"label_text":"Not-Related"}
+{"text":"This is the first report of a catatonic syndrome occurring in a patient receiving disulfiram treatment.","label":1,"label_text":"Related"}
+{"text":"Serotonin reuptake inhibitors, epilepsy and myoclonus.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Topiramate may be associated with ciliochoroidal effusion with forward displacement of the lens-iris diaphragm and anterior chamber shallowing, resulting in acute myopia and angle-closure glaucoma.","label":1,"label_text":"Related"}
+{"text":"KS is a rare complication in glomerular diseases that may (or may not) be related to immunosuppression.","label":0,"label_text":"Not-Related"}
+{"text":"We hypothesize that caffeine toxicity injured the muscle cells, which were fragile due to the potassium depletion induced by the coexisting hyponatremia, to result in unusually severe rhabdomyolysis.","label":1,"label_text":"Related"}
+{"text":"METHODS: Seven young children with RMS were treated from January 1990 through September 1991 with multiagent chemotherapy, organ preserving surgery, and HDR.","label":0,"label_text":"Not-Related"}
+{"text":"Discontinuation of procainamide led to complete recovery.","label":0,"label_text":"Not-Related"}
+{"text":"We present an AIDS patient with severe and prolonged lactic acidosis on stavudine and lamivudine.","label":1,"label_text":"Related"}
+{"text":"Report of a case and review of the literature.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: References for this review were identified by searches of PubMed from 1980 until January 2008 with the terms \"Parkinson disease,\" \"impulse control,\" \"pathologic gambling,\"\"hypersexuality,\" \"levodopa,\" and \"dopamine agonists.\" Articles were also identified through searches of the authors' own files.","label":0,"label_text":"Not-Related"}
+{"text":"Linearity was observed up to 2.0 mg\/L.","label":0,"label_text":"Not-Related"}
+{"text":"However, the increasing dose intensity has not significantly improved the event-free survival.","label":0,"label_text":"Not-Related"}
+{"text":"A patient with rheumatoid arthritis developed an acute intrahepatic cholestasis after 100 mg of sodium aurothiomalate.","label":1,"label_text":"Related"}
+{"text":"Atypical antipsychotic induced mild hypothermia.","label":0,"label_text":"Not-Related"}
+{"text":"The inferior alveolar nerve (IAN) contains mainly sensory fibers.","label":0,"label_text":"Not-Related"}
+{"text":"Two months before admission, MVI was discontinued in the TPN because of the shortage of its supply.","label":0,"label_text":"Not-Related"}
+{"text":"Nine patients were granulocytopenic; the three additional patients with normal granulocyte counts were immunosuppressed.","label":0,"label_text":"Not-Related"}
+{"text":"In 7 CVC-related infections (35%) the catheter was removed.","label":0,"label_text":"Not-Related"}
+{"text":"Potential causes of methamphetamine-related keratitis can be divided into four categories resulting from (a) direct pharmacologic and physical effects of methamphetamine; (b) the toxic effects of diluting or \"cutting\" agents such as lidocaine and quinine; (c) effects related to the route of drug administration (intravenous, inhalation, smoking); and (d) manufacture-related effects of exposure to unintentional caustic contaminants in the final product.","label":1,"label_text":"Related"}
+{"text":"A decreased Arden ratio on EOG (<1.50) was found with an accompanying decreased amplitude of the scotopic b-wave on full-field electroretinography in both eyes.","label":0,"label_text":"Not-Related"}
+{"text":"Transient postoperative pericardial constriction in a child.","label":0,"label_text":"Not-Related"}
+{"text":"After having received gemcitabine on day 1 of the second course, the patient developed dry cough, subfebrile temperatures and dyspnea within 48 h.","label":1,"label_text":"Related"}
+{"text":"Infusion of fresh frozen plasma together with aspirin and dipyridamole resulted in recovery of microangiopathic hemolytic anemia and thrombocytopenia.","label":0,"label_text":"Not-Related"}
+{"text":"Suxamethonium apnoea terminated with commercial serumcholinesterase.","label":1,"label_text":"Related"}
+{"text":"Osteonecrosis is a serious side effect of antiemetic treatment with dexamethasone and this serious complication should be incorporated in the current guidelines.","label":1,"label_text":"Related"}
+{"text":"Nitrendipine is an experimental calcium channel blocking agent that also appears to cause the side effect of drug-induced gingival hyperplasia.","label":1,"label_text":"Related"}
+{"text":"Nevirapine is a non-nucleoside reverse transcriptase inhibitor used in the treatment of human immunodeficiency virus (HIV)-infected patients and in post-exposure prophylaxis.","label":0,"label_text":"Not-Related"}
+{"text":"A number of drugs have been reported to cause neuromuscular blockade and\/or to increase weakness in myasthenia gravis.","label":0,"label_text":"Not-Related"}
+{"text":"Progressive hypoxemia mandated endotracheal intubation 1 week after rituximab administration and led to death 4 weeks after admission.","label":1,"label_text":"Related"}
+{"text":"Renal insufficiency, however, persisted.","label":0,"label_text":"Not-Related"}
+{"text":"Disseminated tuberculosis following second unrelated cord blood transplantation for acute myelogenous leukemia.","label":0,"label_text":"Not-Related"}
+{"text":"In view of the potentially fatal hypersensitivity reaction, we suggest that any patient on multidrug therapy for leprosy needs an urgent referral to a dermatologist if the patient develops a skin rash during the first two months of treatment.","label":0,"label_text":"Not-Related"}
+{"text":"We present clinical data, neuropsychological findings, and results of brain computed tomography or magnetic resonance imaging, electroneuromyography, evoked potentials, single photon emission computed tomography, and positron-emission tomography.","label":0,"label_text":"Not-Related"}
+{"text":"This abdomen CT scan was thought as abnormality pictures of neutropenic enterocolitis.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Hydroxyurea is a cytostatic agent used to treat myeloproliferative disorders and long-term treatment is associated with mucocutaneous adverse events and nail hyperpigmentation.","label":1,"label_text":"Related"}
+{"text":"One was alive with no evidence of disease at 14 month follow-up, while 2 had residual disease after bone marrow transplantation and died of complications at 4 and 5 months after transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"Erythema multiforme bullosum due to rifampicin.","label":1,"label_text":"Related"}
+{"text":"A corneal and external disease specialist performed a complete ophthalmologic exam and obtained medical histories of the patients.","label":0,"label_text":"Not-Related"}
+{"text":"Drug induced suicidal ideation.","label":0,"label_text":"Not-Related"}
+{"text":"Tap (draft) beer and monoamine oxidase inhibitor dietary restrictions.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Topiramate may be associated with ciliochoroidal effusion with forward displacement of the lens-iris diaphragm and anterior chamber shallowing, resulting in acute myopia and angle-closure glaucoma.","label":1,"label_text":"Related"}
+{"text":"Cisapride for the treatment of nausea produced by selective serotonin reuptake inhibitors.","label":0,"label_text":"Not-Related"}
+{"text":"Sodium nitroprusside was stopped and amrinone 100 mg bolus followed by 10 micrograms.kg-1.min-1 was given in addition to adding PEEP to the ventilation.","label":0,"label_text":"Not-Related"}
+{"text":"However, the effect of chemotherapy on cord tolerance is unclear.","label":0,"label_text":"Not-Related"}
+{"text":"Clinically important side effects are infrequent, but diarrhea, usually transient, occurred in about 13 percent, with frank steatorrhea in 2 to 6 percent of cases.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of DCL that developed in the context of the immune reconstitution inflammatory syndrome (IRIS) in a man with AIDS following initiation of antiretroviral therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Vitamin B12 (cyanocobalamin) is an integral component of two biochemical reactions in man: the conversion of L-methylmalonyl coenzyme A into succinyl coenzyme A and the formation of methionine by methylation of homocysteine.","label":0,"label_text":"Not-Related"}
+{"text":"During the first post-treatment days, diffuse lamellar keratitis (DLK) (stage III) developed.","label":0,"label_text":"Not-Related"}
+{"text":"Methanol poisoning in Tunisia: report of 16 cases.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a patient with acute leukemia who developed Horner's syndrome and a severe demyelinating peripheral neuropathy leading to death after receiving high-dose cytosine arabinoside.","label":1,"label_text":"Related"}
+{"text":"This is the first case of TMP-SMX-induced hypersensitivity syndrome associated with the reactivation of a latent viral infection.","label":1,"label_text":"Related"}
+{"text":"Exposure of the fetus to indomethacin by administration of the drug to the mother may cause many side effects, including premature closure of the ductus arteriosus.","label":1,"label_text":"Related"}
+{"text":"Myoglobinuria is a recognised complication of Duchenne muscular dystrophy (DMD), but has only once been reported in ambulant boys on corticosteroid therapy [Dubowitz V, Kinali M, Main M, Mercuri E, Muntoni F.","label":0,"label_text":"Not-Related"}
+{"text":"He had a 1-year history of mechanical aortic valve replacement and coronary stent placement because of myocardial infarction and he was taking warfarin and clopidogrel.","label":0,"label_text":"Not-Related"}
+{"text":"Necropsy findings indicated that the pancreatic adenocarcinoma had metastasized to surrounding tissues and vessels, which was not unexpected given the high grade assigned to the neoplasm during histologic analysis.","label":0,"label_text":"Not-Related"}
+{"text":"Visual acuity improved from finger counting or less to 20\/40 or better in all cases.","label":0,"label_text":"Not-Related"}
+{"text":"High-dose methylprednisolone in a pregnant woman with Crohn's disease and adrenal suppression in her newborn.","label":1,"label_text":"Related"}
+{"text":"It is presumed that her hyperchloremic metabolic acidosis was secondary to cholestyramine because of the similarity to pediatric reports; the rapid and lasting response to intravenous sodium bicarbonate; the absence of another etiology; normal serum potassium, chloride and bicarbonate despite continued spironolactone therapy after recovery.","label":1,"label_text":"Related"}
+{"text":"A 31-year-old man intermittently received 2.5 x 10(8) units of alpha-IFN and 1 x 10(8) units of beta-IFN for treatment of chronic viral hepatitis type B.","label":0,"label_text":"Not-Related"}
+{"text":"This case of linezolid-associated acute interstitial nephritis within the context of a drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a patient treated with linezolid raises concerns about the presumed renal safety of this drug.","label":1,"label_text":"Related"}
+{"text":"HBsAg seroconversion was achieved after an additional 12 months.","label":0,"label_text":"Not-Related"}
+{"text":"Five days after the 3rd booster dose, in November 1996, the dermatosis relapsed on the forearms, trunk, and legs.","label":0,"label_text":"Not-Related"}
+{"text":"Serum glutathione levels were assessed in a patient with genetically proven Unverricht-Lundborg disease (ULD) before and during treatment with the antioxidant N-acetylcysteine (NAC).","label":0,"label_text":"Not-Related"}
+{"text":"The reaction subsided after treatment with diphenhydramine and dexamethasone.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of IDDM which occurred during interferon therapy for chronic hepatitis.","label":1,"label_text":"Related"}
+{"text":"Clonal cytogenetic evolution was evident in 2 of the 3 patients and included an extra Philadelphia chromosome in both.","label":0,"label_text":"Not-Related"}
+{"text":"We report a patient with linear IgA bullous dermatosis and gluten-sensitive enteropathy.","label":0,"label_text":"Not-Related"}
+{"text":"These patients were treated with cholinesterase inhibitors within a post-marketing surveillance study.","label":0,"label_text":"Not-Related"}
+{"text":"Peritonsillar bupivacaine infiltration, a relatively safe method of pain control, is in some centers frequently used by otolaryngologists for pain relief.","label":0,"label_text":"Not-Related"}
+{"text":"Iatrogenic Mycobacterium infection after an epidural injection.","label":0,"label_text":"Not-Related"}
+{"text":"A 74-year old white man was undergoing treatment with palliative chemotherapy for Stage IV Prostate Adenocarcinoma with multiple osteoblastic metastases.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of codeine intoxication in the neonate, in which the drug was prescribed for cough control during an emergency department visit.","label":1,"label_text":"Related"}
+{"text":"Before transfer from the emergency room, she was found to have an elevated serum urea nitrogen and creatinine of 55 and 5.8 mg\/dL (19.6 mmol\/L and 512.7 micromol\/L, respectively).","label":0,"label_text":"Not-Related"}
+{"text":"We present a unique case of GTBM in a patient with myeloma following treatment with Melphalan.","label":1,"label_text":"Related"}
+{"text":"Cutaneous lesions were pleomorphic but the typical picture of ecthyma gangrenosum was common in this group of patients.","label":0,"label_text":"Not-Related"}
+{"text":"The 3-week sulphasalazine syndrome strikes again.","label":1,"label_text":"Related"}
+{"text":"A 52-year-old woman developed symmetric sensorimotor polyneuropathy and cerebellar syndrome after 24 months of amiodarone treatment.","label":1,"label_text":"Related"}
+{"text":"Herein is reported an unusual case of coexistent warfarin-induced skin necrosis and heparin-induced thrombocytopenia following mitral valve replacement for thromboembolic phenomena associated with marantic endocarditis and bronchial adenocarcinoma.","label":1,"label_text":"Related"}
+{"text":"Tularemia--an unusual cause of a solitary pulmonary nodule in the post-transplant setting.","label":0,"label_text":"Not-Related"}
+{"text":"Data suggest that tamoxifen is involved in the pathogenesis.","label":0,"label_text":"Not-Related"}
+{"text":"We report a 76-year-old man who developed an acute blistering eruption following high-dose penicillin treatment for pneumococcal septicaemia.","label":1,"label_text":"Related"}
+{"text":"We report five cases of restless legs syndrome (RLS) and periodic limb movements during sleep (PLMS) that were probably associated with olanzapine.","label":1,"label_text":"Related"}
+{"text":"Agranulocytosis during clozapine therapy.","label":1,"label_text":"Related"}
+{"text":"Our results suggest that HCQ slow oral desensitization is safe, effective, and easy to perform.","label":0,"label_text":"Not-Related"}
+{"text":"Immunological mechanisms are suggested in the pathogenesis of psoriasis and ulcerative colitis.","label":0,"label_text":"Not-Related"}
+{"text":"Edema disappeared two to three days after stopping therapy but reappeared in all five patients after being reexposed to the drugs.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To report a case of Jarisch-Herxheimer reaction (JHR) in a patient with presumed neurosyphilis and HIV.","label":0,"label_text":"Not-Related"}
+{"text":"One month after changing to fosinopril therapy, the patient reported complete resolution of the cough.","label":0,"label_text":"Not-Related"}
+{"text":"This entity may considered in the differential diagnosis of acute onset of colicky abdominal pain in the patient given narcotics.","label":0,"label_text":"Not-Related"}
+{"text":"Caution should be taken when designing estrogen-related experiments involving Brown Norway rats and other potentially sensitive strains.","label":0,"label_text":"Not-Related"}
+{"text":"Biomicroscopy revealed amiodarone corneal deposits.","label":1,"label_text":"Related"}
+{"text":"A 26-year-old Japanese man, who had been receiving medical attention for ulcerative colitis for one year, presented with diffuse erythema and pustules on his face and trunk, malaise, and fever up to 39 degrees C one day after the administration of salazosulfapyridine.","label":1,"label_text":"Related"}
+{"text":"While this could be a chance association, it does raise the question if her neurologic manifestations could be secondary to scleromyxedema.","label":0,"label_text":"Not-Related"}
+{"text":"Sensitization remained demonstrable 2 months after cessation of the former drug.","label":0,"label_text":"Not-Related"}
+{"text":"Conservative lithium administration is recommended for acute manic psychosis and reference is made to the beneficial effects of urea and aminophylline on renal lithium elimination in the active treatment of lithium poisoning.","label":0,"label_text":"Not-Related"}
+{"text":"The remission of nephrotic syndrome after treatment of Strongyloides infection strongly suggests the possibility of Strongyloides-associated glomerulonephritis.","label":0,"label_text":"Not-Related"}
+{"text":"Here, we report a 73-year-old male hydrocephalic patient who had undergone uneventful V-P shunt surgery 9 years ago.","label":0,"label_text":"Not-Related"}
+{"text":"Seizures and extrapyramidal symptoms in a patient with Tourette's syndrome, Asperger's syndrome, and multiple sclerosis treated with interferon beta-1a and clomipramine.","label":1,"label_text":"Related"}
+{"text":"Risperidone is a frequently used member of a new class of atypical antipsychotics-the serotonin-dopamine antagonists (SDAs)-due to its comparatively high efficacy and low D2\/5HT2 binding ratio, which results in a low incidence of extrapyramidal side effects including tardive dyskinesia (TD).","label":1,"label_text":"Related"}
+{"text":"Sunburn may sometimes be a major injury in psoralen users because high doses or inappropriate use of the drug may render the skin extremely sensitive.","label":1,"label_text":"Related"}
+{"text":"There has been mild improvement of her symptoms, but most of the symptoms did not resolve.","label":0,"label_text":"Not-Related"}
+{"text":"The patient underwent bilateral vertebral stenting due to severe stenosis in both intracranial segments of the vertebral arteries.","label":0,"label_text":"Not-Related"}
+{"text":"As compared with an expected number of 0.04 cases of acute myeloblastic leukemia based on patient-years, the observed seven cases correspond to a 175-times increased risk.","label":0,"label_text":"Not-Related"}
+{"text":"A complete clinical remission of the lymphadenopathy was obtained after infusions of rituximab (an anti-CD20 monoclonal antibody), acyclovir, and high-titer anticytomegalovirus immunoglobulin.","label":0,"label_text":"Not-Related"}
+{"text":"Routine microbiological tests were negative.","label":0,"label_text":"Not-Related"}
+{"text":"Three URTI and one associated upper and LRTI were diagnosed in three BMT recipients out of six patients admitted to the BMT unit, during eight-wk period (March and April 2008).","label":0,"label_text":"Not-Related"}
+{"text":"High-dose tamoxifen was recently reported as a novel treatment for patients with malignant gliomas who have failed standard therapies.","label":0,"label_text":"Not-Related"}
+{"text":"Disease behaviour in two patients was classified as penetrating because of concomitant ischiorectal abscesses, while one patient developed a metastatic colon carcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"Coexistent psoriasis and lupus erythematosus treated with alefacept.","label":0,"label_text":"Not-Related"}
+{"text":"The computer-based algebraic method is illustrated for a problem previously analyzed by Monte Carlo simulation.","label":0,"label_text":"Not-Related"}
+{"text":"The patient subsequently developed severe ischemic necrosis of the skin and soft tissue surrounding the catheter site.","label":0,"label_text":"Not-Related"}
+{"text":"PURPOSE: To report a case of angiographically documented cystoid macula edema occurring after switching a pseudophakic patient from latanoprost to bimatoprost.","label":1,"label_text":"Related"}
+{"text":"She had previously taken simvastatin which is metabolized by CYP3A4, without any sign and symptoms of rhabdomyolysis.","label":0,"label_text":"Not-Related"}
+{"text":"The therapeutic significance of increased Hb F levels in homozygous beta thalassemia and sickle cell anemia is exemplified.","label":0,"label_text":"Not-Related"}
+{"text":"A spectrum of diseases.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a patient who experienced chronic nausea and an episode of confusion while treated with a small, stable dose of oral morphine in the setting of mild renal insufficiency.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: Clinical pharmacists and other healthcare professionals should remain cognizant of possible product quality differences within or bioequivalency differences between levothyroxine products.","label":0,"label_text":"Not-Related"}
+{"text":"The results suggest that the development of severe hypocalcemia can be explained on the basis of hypoparathyroidism in relation to hyperphosphatemia, hypomagnesemia, and acute renal failure.","label":0,"label_text":"Not-Related"}
+{"text":"Doxycycline-induced photo-onycholysis.","label":1,"label_text":"Related"}
+{"text":"At such a time, the poor respiratory function makes some diagnostic procedures harmful.","label":0,"label_text":"Not-Related"}
+{"text":"This regimen could prove useful for other patients who develop hypersensitivity reactions to carboplatin and allow therapy to continue.","label":1,"label_text":"Related"}
+{"text":"Diffuse pulmonary uptake of indium-111-labeled leukocytes in drug-induced pneumonitis.","label":0,"label_text":"Not-Related"}
+{"text":"Fatal lung fibrosis caused by paclitaxel toxicity has not been reported In this report, we describe the case of a 62-year-old woman who received six cycles of paclitaxel and carboplatin as combination chemotherapy for advanced ovarian cancer.","label":1,"label_text":"Related"}
+{"text":"Electromyelography confirmed peripheral nerve injuries.","label":0,"label_text":"Not-Related"}
+{"text":"In one case, the patient was successfully treated by orthotopic cardiac transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"Mycobacterium marinum infection complicating Crohn's disease, treated with infliximab.","label":1,"label_text":"Related"}
+{"text":"Typhlitis is usually seen in the setting of severe chemotherapy-induced neutropenia for acute leukaemia.","label":0,"label_text":"Not-Related"}
+{"text":"Immune reconstitution syndrome following initiation of antiretroviral therapy in a patient with HIV infection and multidrug-resistant tuberculosis.","label":0,"label_text":"Not-Related"}
+{"text":"Intravenous were started and a below knee amputation date of admission under spinal anaesthesia.","label":0,"label_text":"Not-Related"}
+{"text":"Local aprotinin injections are used in the treatment of chronic tendinopathy.","label":0,"label_text":"Not-Related"}
+{"text":"The day after clozapine was stopped, while he was still receiving clomipramine 150 mg\/d, he began behaving oddly, started sweating profusely, shivering, and became tremulous, agitated, and confused.","label":1,"label_text":"Related"}
+{"text":"Long-term studies will be needed to demonstrate reversal of endocrine, hepatic and cardiac dysfunction secondary to iron deposition in these patients.","label":0,"label_text":"Not-Related"}
+{"text":"The chemotherapeutics, including vincristine, actinomycin D, and epirubicin in case 1 and vincristine and actinomycin D in case 2, were given before the hepatotoxicity developed.","label":1,"label_text":"Related"}
+{"text":"The encouraging result obtained warrants the use of this combined treatment modality in other patients.","label":0,"label_text":"Not-Related"}
+{"text":"To the best of our knowledge, this is the first report on the treatment of Stenotrophomonas maltophilia bacteremia after living donor liver transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"We present a case of liver failure in a haemophilic patient coinfected with transfusion acquired human immunodeficiency (HIV) and hepatitis C (HCV) viruses.","label":0,"label_text":"Not-Related"}
+{"text":"The major contraindication to the use of intravenous verapamil is recent administration of intravenous beta-blocking agents (i.e., within the past two hours).","label":0,"label_text":"Not-Related"}
+{"text":"In one 12-month period he had 88 separate admissions to an emergency department with severe hypoglycaemic coma requiring intravenous glucose administration.","label":0,"label_text":"Not-Related"}
+{"text":"Progressive interstitial fibrosis with roentgenographic honeycombing developed in the case of a psoriatic patient who had been on a regimen of methotrexate for 18 years.","label":1,"label_text":"Related"}
+{"text":"\"I couldn't believe how tired I was without realizing it until after I finished a course of iron therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Phototesting with ultraviolet B (UV-B) and ultraviolet A (UV-A) radiation revealed decreased minimal erythemal doses for one or both wave bands in all patients tested.","label":0,"label_text":"Not-Related"}
+{"text":"There is a putative role of liothyronine administration in precipitating or activating hyperthyroidism.","label":1,"label_text":"Related"}
+{"text":"We recommended periodic examination of the serum proteins in patients receiving diphenylhydantoin in order to detect development of monoclonal gammopathy.","label":1,"label_text":"Related"}
+{"text":"SUMMARY: A 65-year-old Caucasian man was admitted to the hospital on January 26, 2006, for worsening congestive heart failure (CHF).","label":0,"label_text":"Not-Related"}
+{"text":"We present a case of sotalol-induced bradycardia reversed by glucagon.","label":1,"label_text":"Related"}
+{"text":"Hepatocellular carcinoma in a young woman with prolonged exposure to oral contraceptives.","label":0,"label_text":"Not-Related"}
+{"text":"Rapamycin\/sirolimus (SR), trade named Rapammune (Wyeth-Ayerst, Sydney, Australia), is a potent immunosuppressive drug associated with myelosuppression, hypertension, hyperlipidemia, and infection.","label":1,"label_text":"Related"}
+{"text":"Early surgical intervention, as well as appropriate antimicrobial therapy, is usually necessary.","label":0,"label_text":"Not-Related"}
+{"text":"The nonnucleoside analog nevirapine is an inducer of cytochrome P450 3A4 liver metabolism and has interactions with protease inhibitors and oral contraceptives.","label":0,"label_text":"Not-Related"}
+{"text":"Minor residual neurological signs remained.","label":0,"label_text":"Not-Related"}
+{"text":"To limit this problem, the clinician should decrease the amount of air injected in the epidural space or substitute nitrous oxide for air when injecting steroid agents epidurally.","label":0,"label_text":"Not-Related"}
+{"text":"The aetiology is currently unknown, and treatment difficult, with a poor response to antihistamines.","label":0,"label_text":"Not-Related"}
+{"text":"At postmortem examination, the characteristic microvascular lesions of the hemolytic-uremic syndrome were found in the kidneys.","label":0,"label_text":"Not-Related"}
+{"text":"A large number of eosinophils in AIA polyps were found before steroid treatment and at recurrence, and they were predominantly composed of activated eosinophils (EG2-positive).","label":0,"label_text":"Not-Related"}
+{"text":"Mycotic aneurysm of the descending thoracic aorta in a 2-kg neonate.","label":0,"label_text":"Not-Related"}
+{"text":"Because there were no other obvious causes of renal failure in either patient, we propose that skeletal muscle ischemia developed during vasopressin infusion, followed by release of myoglobin and renal damage.","label":1,"label_text":"Related"}
+{"text":"Acanthamoeba keratitis associated with contact lenses: six consecutive cases of successful management.","label":0,"label_text":"Not-Related"}
+{"text":"A week prior, the patient was started on folic acid 1 mg orally daily and given an injection of vitamin B12 1000 microg intramuscularly that was continued every 3 cycles thereafter.","label":0,"label_text":"Not-Related"}
+{"text":"Cystoid macular edema in a low-risk patient after switching from latanoprost to bimatoprost.","label":1,"label_text":"Related"}
+{"text":"The third patient, treated with 0.5 cc of thrombin, had an uneventful postoperative course.","label":0,"label_text":"Not-Related"}
+{"text":"Benign intracranial hypertension occurred in four young women taking tetracycline for acne; two were also taking vitamin A.","label":0,"label_text":"Not-Related"}
+{"text":"I have described a patient with a prosthetic heart valve in whom the purple toes syndrome developed.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a case of advanced ovarian carcinoma who developed difficulty walking because of marked pain in the lower extremities and loss of proprioception 25 days after treatment with weekly taxol (80 mg\/m(2)x3).","label":1,"label_text":"Related"}
+{"text":"Glucose-6-phosphate dehydrogenase deficiency was present in the former case and was thought to contribute to the lung injury.","label":0,"label_text":"Not-Related"}
+{"text":"Multiple complications of propylthiouracil treatment: granulocytopenia, eosinophilia, skin reaction and hepatitis with lymphocyte sensitization.","label":1,"label_text":"Related"}
+{"text":"We conclude that treatment with ramipril can be employed effectively and safely in GSD Ia patients with nephrotic-range proteinuria.","label":0,"label_text":"Not-Related"}
+{"text":"Within 2 weeks after starting azithromycin, the patient's forced expiratory volume in 1 second increased significantly and a repeat spiral CT chest scan 5 months later, showed a major improvement of the bronchiectasis.","label":0,"label_text":"Not-Related"}
+{"text":"Urokinase treatment of neonatal aortoiliac thrombosis caused by umbilical artery catheterization: a case report.","label":0,"label_text":"Not-Related"}
+{"text":"Successful treatment of ventricular assist device associated ventricular thrombus with systemic tenecteplase.","label":0,"label_text":"Not-Related"}
+{"text":"He responded favorably to hemodialysis.","label":0,"label_text":"Not-Related"}
+{"text":"The patient developed pulmonary hypertension without a prior diagnosed cardiac and\/or pulmonary disease.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Itraconazole-induced liver injury presents with a cholestatic pattern of injury with damage to the interlobular bile ducts, possibly leading to ductopenia.","label":1,"label_text":"Related"}
+{"text":"Acute renal failure with severe tubulointerstitial changes in a patient with minimal change nephrotic syndrome treated with enalapril.","label":1,"label_text":"Related"}
+{"text":"This case illustrates the importance of dermatological manifestations of systemic disease as an accessible source for diagnosis and guidance in appropriate therapy.","label":0,"label_text":"Not-Related"}
+{"text":"In the two cases, a combination of iloprost, a stable prostacyclin analogue (1 to 2 ng\/kg\/mn) with aspirin and dipyridamole was shown to inhibit ex vivo the heparin-induced platelet aggregation.","label":0,"label_text":"Not-Related"}
+{"text":"The median serum lead was 2.5 micro mol\/L (range 1.38-4.83).","label":0,"label_text":"Not-Related"}
+{"text":"After seven months' continuous treatment for suspected tuberculosis with rifampicin and ethambutol a nine-year-old boy developed polyarthritis, rash and hepatitis in association with anti-native DNA antibodies and positive antinuclear factor.","label":1,"label_text":"Related"}
+{"text":"The patients evidenced improvement with olanzapine that equated to 16- to 31-point decreases in rating scale scores during 1-year follow-up without any hematologic abnormalities.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment with isotretinoin appeared to shorten her recovery period.","label":0,"label_text":"Not-Related"}
+{"text":"However, the magnitude of such false positivity has not been previously reported.","label":0,"label_text":"Not-Related"}
+{"text":"A renal biopsy specimen on hospital day 9 showed tubular damage with minimal glomerular changes consistent with a diagnosis of nonsteroidal agent-induced nephropathy.","label":0,"label_text":"Not-Related"}
+{"text":"Both agents are excreted by the kidneys, raising the possibility that acyclovir at high serum concentrations may interfere with the renal excretion of lithium.","label":0,"label_text":"Not-Related"}
+{"text":"These observations confirm that ecthyma gangrenosum may be a primary cutaneous disorder not systematically associated with bacteremia.","label":0,"label_text":"Not-Related"}
+{"text":"Local anesthetic switching for intrathecal tachyphylaxis in cancer patients with pain.","label":0,"label_text":"Not-Related"}
+{"text":"(2) In 8 out of 13 cases without recombinant human EPO treatment before PTX, a 10% increase in RBC was observed after PTX.","label":0,"label_text":"Not-Related"}
+{"text":"A lasting change in trazodone response after non-convulsive electroshock therapy for medication-resistant senile depression.","label":0,"label_text":"Not-Related"}
+{"text":"Mammary gigantism is a rare complication of D-penicillamine treatment.","label":1,"label_text":"Related"}
+{"text":"Adrenal suppression in a fetus due to administration of methylprednisolone has hitherto been rarely published.","label":1,"label_text":"Related"}
+{"text":"Three of the six had the OGC develop as a tardive side-effect, and in one patient the episodes persisted for some months after the cessation of the offending neuroleptic drug.","label":0,"label_text":"Not-Related"}
+{"text":"Post-transfusion purpura: response to steroids and association with red blood cell and lymphocytotoxic antibodies.","label":0,"label_text":"Not-Related"}
+{"text":"This case illustrates that posttransplant primary cutaneous CD30+ anaplastic large cell lymphomas may assume an aggressive clinical course but can still be controlled by systemic chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"A woman 38-year-old, suffering for about ten years from multiple sclerosis and treated with repeated therapy cycles of intrathecal Depo-Medrol, developed a spastic paraparesis at the lower limbs.","label":1,"label_text":"Related"}
+{"text":"Erections reported with other dopamine agonists and levodopa are probably mediated by the same mechanism.","label":0,"label_text":"Not-Related"}
+{"text":"Within 24 hours of fluid restriction and cessation of desmopressin, her symptoms and hyponatremia resolved.","label":1,"label_text":"Related"}
+{"text":"He continued inhaled tobramycin 300 mg twice daily, his home doses of pancreatic replacement enzymes and vitamins, albuterol 2.5 mg by high flow nebulizer (HFN) 4 times daily, and dornase alpha 2.5 by HFN daily.","label":0,"label_text":"Not-Related"}
+{"text":"Jude total therapy studies XIII.","label":0,"label_text":"Not-Related"}
+{"text":"The relationship between this paraneoplastic endocrine syndrome and the clinical course of the tumor is examined in this review of patients with the ectopic ACTH syndrome and small cell carcinoma seen at The Johns Hopkins Oncology Center between 1973 and 1979.","label":0,"label_text":"Not-Related"}
+{"text":"Here, we describe levofloxacin-induced delirium with psychotic features in a relatively young, otherwise healthy female.","label":1,"label_text":"Related"}
+{"text":"We report a patient with pulmonary adenocarcinoma complicated by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) following systemic chemotherapy with cisplatin (CDDP) and vindesine (VDS).","label":1,"label_text":"Related"}
+{"text":"With an increasing trend towards re-treating patients with known IIRs, clinicians should be aware of this potentially serious and previously unreported complication.","label":0,"label_text":"Not-Related"}
+{"text":"Both patients subsequently developed markedly elevated EBV-DNA titers in association with monoclonal, light chain-restricted B cell populations in the blood.","label":0,"label_text":"Not-Related"}
+{"text":"Routine serum chemistry and full blood cell count (apart from neutrophil count) were normal.","label":0,"label_text":"Not-Related"}
+{"text":"A 16-month-old male presented to the Emergency Department cyanotic and short of breath after ingestion of a hair-care-equipment cleaning solution.","label":0,"label_text":"Not-Related"}
+{"text":"Interferon-beta (IFN-beta) is a type I interferon used in the management of multiple sclerosis.","label":0,"label_text":"Not-Related"}
+{"text":"The current report describes a man who was prescribed zonisamide for epilepsy and subsequently developed widespread skin rash, acute kidney injury, high-grade fever, eosinophilia, liver dysfunction, lymphadenopathy and an increase in antihuman herpesvirus-6 immunoglobulin G titer.","label":1,"label_text":"Related"}
+{"text":"The reaction to sodium sulfite in the next patch testing was negative.","label":0,"label_text":"Not-Related"}
+{"text":"Histological examination of the resected specimen demonstrated the strong affinity for Congo red and yellow-green birefringence that are characteristic of cerebral amyloid angiopathy.","label":0,"label_text":"Not-Related"}
+{"text":"Acute hemorrhagic gastritis associated with acetazolamide intoxication in a patient with chronic renal failure.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: Owing to the potential for increased toxicity, the combination of raltitrexed and mitomycin-C cannot be recommended as first-line treatment in patients with advanced colorectal cancer.","label":0,"label_text":"Not-Related"}
+{"text":"Such cells were present in far greater numbers than are usually seen in untreated patients with HS or patients with HS undergoing successful bone marrow transplantation without GM-CSF.","label":0,"label_text":"Not-Related"}
+{"text":"The course of a seasonal bipolar disorder influenced by caffeine.","label":0,"label_text":"Not-Related"}
+{"text":"They fear that beta-blockers will block adrenergic symptoms, and patients will not know when they are hypoglycemic.","label":0,"label_text":"Not-Related"}
+{"text":"Gonioscopy revealed the presence of a scleral abscess, which responded to subconjunctival injection of vancomycin and an intense and prolonged course of topical antibiotics.","label":0,"label_text":"Not-Related"}
+{"text":"After therapy for diabetic coma with insulin (containing the preservative cresol) and electrolyte solutions was started, the patient complained of increasing myalgia, developed a high fever and respiratory and metabolic acidosis and lost consciousness.","label":1,"label_text":"Related"}
+{"text":"A case of severe visual loss following a single dose of vincristine is described.","label":1,"label_text":"Related"}
+{"text":"Delayed immune reconstitution after SCT, such as cord blood and T-cell depleted SCT with the use of alemtuzumab, has been associated with an increased frequency of CMV disease as well as CMV reactivation.","label":0,"label_text":"Not-Related"}
+{"text":"Antidepressants and myoclonus: case report.","label":0,"label_text":"Not-Related"}
+{"text":"This case presentation is of a patient who had the clinical appearance of epiglottitis, but actually had an oro-pharyngeal dystonic reaction to prochlorperazine.","label":1,"label_text":"Related"}
+{"text":"This trial was designed to evaluate intraarticular delivery of a tumor necrosis factor alpha (TNF-alpha) antagonist, through an adeno-associated virus (AAV) type 2 delivery system, for inflammatory arthritis.","label":0,"label_text":"Not-Related"}
+{"text":"Therapy consisted of 3 cycles of induction cisplatin\/5-fluorouracil chemotherapy followed by radiotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Recent studies have shown that under experimental conditions ferrous sulfate may reduce the gastrointestinal absorption of orally administered levothyroxine sodium in patients with primary hypothyroidism.","label":1,"label_text":"Related"}
+{"text":"However, clinical manifestations and treatment options have rarely been described in the pediatric literature.","label":0,"label_text":"Not-Related"}
+{"text":"Post marketing studies of Interferon-beta (IFN beta) therapy in multiple sclerosis (MS) have demonstrated surprisingly high rates of hepatotoxicity.","label":1,"label_text":"Related"}
+{"text":"These data confirm the therapeutic value of arsenic trioxide in relapsed\/resistant APL.","label":0,"label_text":"Not-Related"}
+{"text":"These subjective sensory phenomena were not associated with sensory loss or autonomic or motor signs.","label":0,"label_text":"Not-Related"}
+{"text":"Spinal myoclonus resembling belly dance.","label":0,"label_text":"Not-Related"}
+{"text":"CASE: A patient was admitted to hospital with preterm contractions and cervical insufficiency at 28 weeks of gestation.","label":0,"label_text":"Not-Related"}
+{"text":"Immune-mediated hemolytic anemia is a well-recognized complication of hematopoietic stem cell transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"We report a 4-year-old girl who presented with acute bilateral blindness, a focal seizure and hypertension 10 days after commencing oxybutynin to treat enuresis.","label":1,"label_text":"Related"}
+{"text":"The case is presented of a 35-year-old woman with major thrombotic obstruction of a 29-mm St.","label":0,"label_text":"Not-Related"}
+{"text":"One month after that, sperm motility was vastly improved (65%) and they conceived a child 5 months after that.","label":0,"label_text":"Not-Related"}
+{"text":"Death from chemotherapy in gestational trophoblastic disease.","label":0,"label_text":"Not-Related"}
+{"text":"Although gabapentin withdrawal has been previously reported and usually consists of anxiety, diaphoresis, and palpitations, this is the first reported patient with generalized seizures and status epilepticus secondary to gabapentin withdrawal.","label":1,"label_text":"Related"}
+{"text":"This is a retrospective analysis of the complete autopsy records and clinical histories of 500 adults who underwent organ transplantation at the University of Pittsburgh Medical Center during the interval of March, 1981 through July, 1997.","label":0,"label_text":"Not-Related"}
+{"text":"Hypersensitivity reactions due to chloramphenicol are rarely reported in the literature.","label":1,"label_text":"Related"}
+{"text":"This article considers treating patients in the first 2 years of rheumatoid arthritis with low dose of oral corticosteroids.","label":0,"label_text":"Not-Related"}
+{"text":"To the best of the authors' knowledge, this is the first reported case of Propecia-associated cataract.","label":1,"label_text":"Related"}
+{"text":"To our knowledge, no cases of glaucoma have been reported so far.","label":0,"label_text":"Not-Related"}
+{"text":"This is the first description of BRONJ involving the skull base.","label":0,"label_text":"Not-Related"}
+{"text":"The elderly are also particularly prone to develop toxic side effects from standard antidepressive agents.","label":0,"label_text":"Not-Related"}
+{"text":"A 31-year-old female was found to have FIGO Stage IIB squamous cell carcinoma of the cervix.","label":0,"label_text":"Not-Related"}
+{"text":"Although a surgical approach has been emphasized in patients with peripheral vein suppurative thrombophlebitis, anticoagulation therapy may be a useful alternative in the treatment of patients with central vein infection.","label":0,"label_text":"Not-Related"}
+{"text":"On admission, he presented with clinical features of chronic GVHD including transient exacerbation of cholestatic liver injury.","label":0,"label_text":"Not-Related"}
+{"text":"CASES: Two postmenopausal women treated with tamoxifen and progestational agents for breast carcinoma developed uterine enlargement and intermittent spotting.","label":1,"label_text":"Related"}
+{"text":"Hypertension develops in most patients after transplantation when immunosuppression is based on cyclosporine and prednisone.","label":1,"label_text":"Related"}
+{"text":"Well tolerated, midodrine appears to be a suitable and effective agent as it raises blood pressure significantly via its effect on peripheral alpha-adrenergic receptors.","label":0,"label_text":"Not-Related"}
+{"text":"Preoperative prophylaxis for C1 esterase-inhibitor deficiency in patients undergoing oral surgery: a report of three cases.","label":0,"label_text":"Not-Related"}
+{"text":"We report 5 patients (3 patients with chronic hepatitis C treated with pegylated interferon alfa-2b in association with oral ribavirin and two patients with chronic myelocytic leukemia) who developed local cutaneous reactions at sites of injection after the administration of weekly subcutaneous injections of pegylated interferon alfa-2b at different doses.","label":1,"label_text":"Related"}
+{"text":"Six of the patients were no longer receiving vigabatrin.","label":0,"label_text":"Not-Related"}
+{"text":"Pulmonary eosinophilia or granulomas, classically seen in previously reported cases of methotrexate pneumonitis, were not observed.","label":1,"label_text":"Related"}
+{"text":"Setting.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: We examined trends in Accutane use by reproductive-aged women.","label":0,"label_text":"Not-Related"}
+{"text":"Tolerance to cannabis was not reported.","label":0,"label_text":"Not-Related"}
+{"text":"On the 7th day, these values reached a maximum, i.e. 95 and 160% of the control, respectively.","label":0,"label_text":"Not-Related"}
+{"text":"Discontinuation of methicillin therapy and appropriate antibiotic treatment of endocarditis led to clinical improvement, emphasizing the need to promptly discontinue potential nephrotoxic agents when abnormalities in renal function appear.","label":0,"label_text":"Not-Related"}
+{"text":"Data are presented to show that atopic cataracts and steroid cataracts can be similar in appearance and cannot be distinguished from one another in many cases.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Symptomatic epiphora of the affected eyes was reduced after 2 weeks.","label":0,"label_text":"Not-Related"}
+{"text":"A dapsone hypersensitivity syndrome, consisting of fever, headache, nausea, vomiting, lymphadenopathy, hepatitis, hemolysis, leukopenia, and mononucleosis, has been described in patients treated with the drug for leprosy.","label":1,"label_text":"Related"}
+{"text":"We have found no reports describing a technique for making custom hand-made articulating spacers.","label":0,"label_text":"Not-Related"}
+{"text":"A  number of similarities, including the fact that both medications are 250-mg white tablets, with similar generic and brand names which are generically repackaged medications juxtaposed on the pharmacist's shelf, predispose to the inadvertent substitution of one medication for the other.","label":0,"label_text":"Not-Related"}
+{"text":"They were studied clinically and with a representative range of in vitro and in vivo tests of immune function.","label":0,"label_text":"Not-Related"}
+{"text":"This case report describes a very rare complication of S. aureus sepsis in a 62-year-old haemodialysis patient, namely a suprarenal aneurysm of the abdominal aorta.","label":0,"label_text":"Not-Related"}
+{"text":"Rapamycin\/sirolimus (SR), trade named Rapammune (Wyeth-Ayerst, Sydney, Australia), is a potent immunosuppressive drug associated with myelosuppression, hypertension, hyperlipidemia, and infection.","label":1,"label_text":"Related"}
+{"text":"Her immunoglobulins in serum were checked on PHT and after 15 years treatment with carbamazepine.","label":0,"label_text":"Not-Related"}
+{"text":"We report a child with yolk sac tumor who developed localized pigmentation after the first course of chemotherapy regimen that included cisplatin, etoposide and bleomycin.","label":1,"label_text":"Related"}
+{"text":"After stereotactic aspiration of the abscess, successful treatment was achieved by triple therapy with trimethoprim sulfamethoxazole (TMP\/SMX), ceftriaxone and amikacin.","label":0,"label_text":"Not-Related"}
+{"text":"A 26-year-old HIV-seropositive Caucasian man with cryptococcal meningitis developed permanent bilateral blindness shortly after starting highly active antiretroviral treatment.","label":0,"label_text":"Not-Related"}
+{"text":"A syndrome of increased affect in response to risperidone among patients with schizophrenia.","label":1,"label_text":"Related"}
+{"text":"An enucleation specimen was examined by light microscopy.","label":0,"label_text":"Not-Related"}
+{"text":"A 52-year-old woman suffered from chronic active hepatitis type C and was treated with a total of 456 x 10(6) units of IFN-alpha for 23 weeks.","label":0,"label_text":"Not-Related"}
+{"text":"In patients with swallowing dysfunction and pneumonia, a history of mineral oil use should be obtained and a diagnosis of ELP should be considered in the differential diagnoses if mineral oil use has occurred.","label":1,"label_text":"Related"}
+{"text":"The traditional treatment for melanoma recurrences on an extremity has been surgical excision or less often amputation.","label":0,"label_text":"Not-Related"}
+{"text":"Extremely high exposures in an obese patient receiving high-dose cyclophosphamide, thiotepa and carboplatin.","label":0,"label_text":"Not-Related"}
+{"text":"A self-expanding metallic stent (Wallstent) was used to relieve obstruction of the common bile duct in a young male with a desmoplastic small cell tumor of the abdomen.","label":0,"label_text":"Not-Related"}
+{"text":"The need for professional support for the carers of such patients should be recognized.","label":0,"label_text":"Not-Related"}
+{"text":"A 58-year-old man with rheumatoid arthritis developed lichen planus during treatment with gold.","label":1,"label_text":"Related"}
+{"text":"We report a case of a young woman with SLE and thrombocytopenia, who developed severe perspiration, headache, and seizure after receiving cyclosporine.","label":1,"label_text":"Related"}
+{"text":"Systemic cyclosporin (10 mg\/kg\/day) resulted in resolution of the corneal ulceration within two weeks of beginning treatment, and the patient has remained in remission after 15 months of therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Several reports have emphasized the need for a loading dose in order to achieve therapeutic blood levels rapidly.","label":0,"label_text":"Not-Related"}
+{"text":"Two cases of mequitazine-induced photosensitivity reactions.","label":1,"label_text":"Related"}
+{"text":"Ischemic cholangitis caused by transcatheter hepatic arterial chemoembolization 10 months after resection of the extrahepatic bile duct.","label":0,"label_text":"Not-Related"}
+{"text":"Discontinuing the drug quickly resulted in disappearance of the dyspnea.","label":0,"label_text":"Not-Related"}
+{"text":"Shortly after a meal, symptoms are associated with hyperglycemia (early dumping), followed by late dumping symptoms associated with reactive hypoglycemia.","label":0,"label_text":"Not-Related"}
+{"text":"Cephalosporins are most likely associated with Vitamin K deficiency.","label":1,"label_text":"Related"}
+{"text":"Arterial occlusive events during chemotherapy for germ cell cancer.","label":0,"label_text":"Not-Related"}
+{"text":"This report suggests that anemia can occur due to MMF, in particular when it is given with prednisone, a side effect well documented in the transplantation literature when the triple combination of MMF, cyclosporine and prednisone is used.","label":1,"label_text":"Related"}
+{"text":"A fifty-five-year-old male patient underwent total laryngectomy, bilateral modified radical neck dissection, and primary voice restoration for squamous cell carcinoma of the supraglottic larynx.","label":0,"label_text":"Not-Related"}
+{"text":"These cases and others quoted indicate that dependence on pressurized aerosol bronchodilators can and does occur in young people.","label":0,"label_text":"Not-Related"}
+{"text":"SETTING: A neuro-ophthalmology referral center.","label":0,"label_text":"Not-Related"}
+{"text":"The daily infusion of IgG had to be suspended after three days in the second patient with encephalitis and nephritis, because the renal function rapidly deteriorated; subsequently, six plasma exchanges led to an almost complete recovery.","label":0,"label_text":"Not-Related"}
+{"text":"Remarkable findings on initial examination were facial grimacing, flexure posturing of both upper extremities, and 7-mm, reactive pupils.","label":0,"label_text":"Not-Related"}
+{"text":"Four patients were neutropenic (less than 500\/microliters).","label":0,"label_text":"Not-Related"}
+{"text":"CASE REPORT: A 32-year-old man with lymphoblastic lymphoma received treatment with daunorubicin, vincristine, and prednisone.","label":0,"label_text":"Not-Related"}
+{"text":"RATIONALE: Taking psychotropic medications is frequently problematic from both consumers' and caregivers' perspective.","label":0,"label_text":"Not-Related"}
+{"text":"Therefore, ocular examination at baseline and every 6 months is indicated for patients receiving a regimen of amiodarone and\/or digoxin therapy.","label":0,"label_text":"Not-Related"}
+{"text":"She was started on amlodipine 2.5 mg orally once daily, a nitroglycerin patch (0.4 mg\/h), and warfarin 5 mg orally once daily.","label":0,"label_text":"Not-Related"}
+{"text":"In the mean-time the drug is available in Canada and England but not in the U.S.","label":0,"label_text":"Not-Related"}
+{"text":"A 10-year-old girl with Lennox-Gastaut syndrome who received intravenous lorazepam for atypical absence status seizures is reported.","label":1,"label_text":"Related"}
+{"text":"INTERVENTIONS: Treatment with clonazepam.","label":0,"label_text":"Not-Related"}
+{"text":"He failed to improve when therapy was continued with low-molecular-weight (LMW) heparin (Fragmin, Kabi Pfrimmer, Erlangen, FRG).","label":0,"label_text":"Not-Related"}
+{"text":"All patients had previous mucocutaneous reactions to chrysotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Clinical and laboratory manifestations resolved after cessation of methysergide therapy.","label":0,"label_text":"Not-Related"}
+{"text":"The history of desmopressin use was not obtained at that time.","label":0,"label_text":"Not-Related"}
+{"text":"The clinical course of this patient did not support a cause-and-effect relationship between obidoxime and the abnormal liver function.","label":0,"label_text":"Not-Related"}
+{"text":"A 16-year-old boy developed fever, generalized rigidity, leukocytosis, and increased serum transaminase and creatine kinase levels while receiving treatment with olanzapine and lithium.","label":1,"label_text":"Related"}
+{"text":"Ventriculo-peritoneal shunting led to complete reversal of hydrocephalus with progressive disappearance of the acute encephalopathy.","label":0,"label_text":"Not-Related"}
+{"text":"Toxic encephalopathy related to antihistamine-barbiturate antiemetic medication.","label":0,"label_text":"Not-Related"}
+{"text":"Bromide intoxication secondary to pyridostigmine bromide therapy.","label":1,"label_text":"Related"}
+{"text":"One year later, a progressive increase in policlonal gamma-globulin and a decrease in the CD4+ lymphocyte count to below 500\/muL were detected in concomitance with ultrasonographic evidence of a progressive increase in the longitudinal diameters of the liver and spleen and signs of liver inhomogeneity.","label":0,"label_text":"Not-Related"}
+{"text":"The patient showed no initial evidence of being a latent HBV carrier.","label":0,"label_text":"Not-Related"}
+{"text":"Physical examination revealed diaphoresis, low-grade fever, hypertension, tachycardia, bilateral cogwheel rigidity, hyperreflexia, tremor, and myoclonus, symptoms and signs that are consistent with severe SS.","label":0,"label_text":"Not-Related"}
+{"text":"A 54-year-old man received combination chemotherapy with nedaplatin and irinotecan as salvage chemotherapy for refractory non-seminomatous testicular cancer.","label":0,"label_text":"Not-Related"}
+{"text":"Three cases of acute renal toxicity in patients receiving long-term therapy with mitomycin C and 5-fluorouracil are reported.","label":1,"label_text":"Related"}
+{"text":"Six years after treatment he had a progressive increase in the platelet count and was diagnosed as essential thrombocythemia.","label":0,"label_text":"Not-Related"}
+{"text":"A 23-year-old woman with systemic lupus erythematosus had a severe hypersensitivity reaction to the drug ibuprofen.","label":1,"label_text":"Related"}
+{"text":"Intraoperative Healon5 injection into blebs for small conjunctival breaks created during trabeculectomy.","label":0,"label_text":"Not-Related"}
+{"text":"Intra-operatively, he suffered inadvertent injury to an intercostal arterial branch during isolation of the aorta below the graft.","label":0,"label_text":"Not-Related"}
+{"text":"There was no evidence of worsening of the myotonic symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"Here, we report on six cases of NE in patients with acute leukemias.","label":0,"label_text":"Not-Related"}
+{"text":"Life-threatening hypokalaemia and quadriparesis in a patient with ureterosigmoidostomy.","label":0,"label_text":"Not-Related"}
+{"text":"Since their introduction in 2006, the tyrosine kinase inhibitors (TKI) Sunitinib and Sorafenib have become the standard of care for many patients with renal cancer.","label":0,"label_text":"Not-Related"}
+{"text":"We report a series of 16 cases of methanol poisoning admitted to our Intensive Care Unit between December 2003 and April 2004.","label":0,"label_text":"Not-Related"}
+{"text":"He had been abusing ergotamine compounds for several years on at least 15 days per month.","label":0,"label_text":"Not-Related"}
+{"text":"Protamine-induced fatal anaphylaxis.","label":1,"label_text":"Related"}
+{"text":"Fulminant hepatic failure developed in a 24-year-old black woman who had been treated with propylthiouracil and propranolol for hyperthyroidism.","label":1,"label_text":"Related"}
+{"text":"Tricyclic antidepressant (TCA) morbitity is primarily due to cardiac arrhythmias and hypotension, which become more refractory to treatment as acidosis progresses (Ann Emerg Med. 1985;14:1-9; Clin Toxicol. 2007;45:203-233; Flomenbaum N, Goldfrank L, Hoffman R, et al. Goldfrank's toxicologic emergencies. 8th ed. McGraw-Hill Companies, Inc, 2006).","label":0,"label_text":"Not-Related"}
+{"text":"He began taking propafenone only 6 days prior to admission because of uncontrolled atrial fibrillation and symptoms of fatigue.","label":0,"label_text":"Not-Related"}
+{"text":"This is a case of pseudoephedrine-induced intracerebral hemorrhage in a patient with an underlying vascular malformation.","label":1,"label_text":"Related"}
+{"text":"Systemic complications associated with retinal cryoablation for retinopathy of prematurity.","label":0,"label_text":"Not-Related"}
+{"text":"Magnetic resonance imaging of the spinal cord disclosed signal-intensity abnormalities from C4 to C3.","label":0,"label_text":"Not-Related"}
+{"text":"Typically, it occurs in a patient with preexisting structural heart disease (20 of 24 [83%]) and often with some form of recent dental infection or manipulation (18 of 24 [75%]).","label":0,"label_text":"Not-Related"}
+{"text":"Two months after the operation in the right eye the patient presented with active infection in the left eye.","label":0,"label_text":"Not-Related"}
+{"text":"Consistent with the data in healthy volunteers, a major interaction between esomeprazole and atazanavir-ritonavir was observed in this patient-marked reductions in atazanavir trough plasma concentration and in the area under the concentration-time curve from 0-24 hours-whereas an interaction between esomeprazole and fosamprenavir-ritonavir was not apparent in this patient.","label":0,"label_text":"Not-Related"}
+{"text":"The patient presented with lethargy, abdominal pain, and vomiting.","label":0,"label_text":"Not-Related"}
+{"text":"A major advantage of genotyping compared with phenotyping is that the former may be performed in blood samples from patients irrespective of treatment.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: Although intravenous corticosteroid treatment for uveitis associated with multiple sclerosis can be very helpful, the patient should be monitored closely for systemic side effects.","label":0,"label_text":"Not-Related"}
+{"text":"Hepatic adenomas are rare tumors; they have been associated with the use of anabolic steroids.","label":0,"label_text":"Not-Related"}
+{"text":"Remissions following treatment of individual lesions varied from one month to at least three years.","label":0,"label_text":"Not-Related"}
+{"text":"In this case, interferon alpha induced polymyositis and cardiomyopathy is diagnosed in a 33-yr-old male patient with history of chronic hepatitis B.","label":1,"label_text":"Related"}
+{"text":"Her treatment was complicated by hypocalcemia and thrombocytopenia.","label":0,"label_text":"Not-Related"}
+{"text":"Recognized side effects include fatigue and constipation.","label":0,"label_text":"Not-Related"}
+{"text":"Additionally, we showed conclusively that under certain circumstances (that is, corneal scarring) tandem scanning confocal microscopy can resolve the double-walled structure of the Acanthamoeba ectocyst surrounding the endocyst.","label":0,"label_text":"Not-Related"}
+{"text":"NE occurred 7-10 days after the completion of chemotherapy, during the neutropenic phase.","label":0,"label_text":"Not-Related"}
+{"text":"We experienced a male patient with psoriasis and hypertension whose conditions were treated with tacalcitol ointment and thiazide, respectively, resulting in hypercalciuria and hypercalcemia.","label":1,"label_text":"Related"}
+{"text":"These patients all suffered unnecessary morbidity or investigations.","label":0,"label_text":"Not-Related"}
+{"text":"This disease is caused by inherited defects of the insulin receptor and is lethal early in life.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Clinicians should be aware of a risk of serotonin syndrome with serious extrapyramidal reactions in patients receiving sertraline or venlafaxine when metoclopramide is coadministered even in a single, conventional dose.","label":1,"label_text":"Related"}
+{"text":"She underwent emergent surgical valve replacement.","label":0,"label_text":"Not-Related"}
+{"text":"Late development of diabetes mellitus after interferon-alfa and ribavirin therapy for chronic hepatitis C: a case report.","label":1,"label_text":"Related"}
+{"text":"One man who had acute urinary retention before treatment was subsequently able to void extremely well.","label":0,"label_text":"Not-Related"}
+{"text":"In contrast to other reports regarding disseminated M. genavense infection, the patient is still alive and well.","label":0,"label_text":"Not-Related"}
+{"text":"The clinical presentation mimicked a viral exanthema.","label":0,"label_text":"Not-Related"}
+{"text":"However, this class of drugs has been associated with tic exacerbations, thus limiting their utility in this patients subgroup.","label":0,"label_text":"Not-Related"}
+{"text":"All eyes had conjunctival congestion and mild to severe corneal edema with Descemet's folds.","label":0,"label_text":"Not-Related"}
+{"text":"Flare of Kaposi's sarcoma (KS) is well described in immunosuppressed patients treated with corticosteroids and rituximab, but has not yet been reported during treatment with imatinib.","label":1,"label_text":"Related"}
+{"text":"Ciclosporin was administered, allowing corticosteroid therapy to be discontinued.","label":0,"label_text":"Not-Related"}
+{"text":"The recovery of the pneumococcal meningitis was complicated by severe neurological impairment.","label":0,"label_text":"Not-Related"}
+{"text":"A skin biopsy specimen revealed microscopic, sterile, neutrophilic abscesses.","label":0,"label_text":"Not-Related"}
+{"text":"Upon a chlorpromazine minimal effective dose reduction, target behaviors increased and dosage was returned to prior levels with the conclusion that chlorpromazine was controlling the target behaviors.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of pancytopenia in a 23-year-old man with Crohn's disease who was treated with 5-aminosalicylic acid (Pentasa; Nisshin, Tokyo, Japan) 3.0 g\/day.","label":1,"label_text":"Related"}
+{"text":"Phantom limb pain as a manifestation of paclitaxel neurotoxicity.","label":1,"label_text":"Related"}
+{"text":"Shakuyaku-kanzo-to (SKT) is a traditional herbal medicine that is widely used for muscular cramp and abdominal pain.","label":0,"label_text":"Not-Related"}
+{"text":"The present case is the first report of hypercalcemia induced by vitamin D3 ointment and thiazide simultaneously.","label":1,"label_text":"Related"}
+{"text":"A 47 year-old woman who had a 4-year history of intramuscular pentazocine injections in the lower extremities, developed gradual stiffness and weakness of the lower extremities.","label":1,"label_text":"Related"}
+{"text":"A 37-year-old woman with relapsing invasive vertebral aspergillosis received intravenous VRC and developed angio-oedema 10 days after starting therapy.","label":1,"label_text":"Related"}
+{"text":"We strongly suspect that this lethal anuria was mainly due to ifosfamide, occurring in a patient having received previous cisplatin chemotherapy and with poor kidney perfusion due to transient hypotension.","label":1,"label_text":"Related"}
+{"text":"A 64 year old woman with previous history of coronary stenting five days before was admitted in our institution for intracranial bleeding while receiving aspirin and clopidogrel.","label":1,"label_text":"Related"}
+{"text":"When using local anaesthetic epidural infusions, it is important to exclude other causes of motor block before attributing it to the local anaesthetic.","label":0,"label_text":"Not-Related"}
+{"text":"A patient with Wegener's granulomatosis rapidly developed a circumferential subglottic stenosis while on a cyclophosphamide regimen that had caused resolution of systemic symptoms and pulmonary infiltrates.","label":1,"label_text":"Related"}
+{"text":"High-dose cytosine arabinoside may benefit patients with refractory acute leukemia.","label":0,"label_text":"Not-Related"}
+{"text":"A 22-year-old drug-abuser injected flunitrazepam tablets dissolved in tap water into her left femoral artery and presented with clinical signs of acute ischaemia of the left leg.","label":1,"label_text":"Related"}
+{"text":"Two cases of pneumococcal sepsis, meningitis and unilateral endophthalmitis after total splenectomy are described.","label":0,"label_text":"Not-Related"}
+{"text":"We present a rare case of retinoid-induced sclerotic changes of lumbar spine and femur demonstrated by dual energy x-ray absorptiometrie (DEXA).","label":0,"label_text":"Not-Related"}
+{"text":"Patient 1 presented bilateral ballism 1 week after intravenous heroin injection.","label":1,"label_text":"Related"}
+{"text":"PURPOSE: The case of a patient who developed aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension simultaneously during treatment with trimethoprim-sulfamethoxazole is described.","label":1,"label_text":"Related"}
+{"text":"A patient with chest pain was found to have obstructive hypertrophic cardiomyopathy.","label":0,"label_text":"Not-Related"}
+{"text":"We present a case of thrombosis of the right internal jugular vein presenting as a neck lump to the ENT department.","label":0,"label_text":"Not-Related"}
+{"text":"Neither the prior history of psychiatric illness nor brain damage predisposed to such response on treatment, and in most patients, it was not a part of hypomania or a more diffuse psychiatric disturbance.","label":0,"label_text":"Not-Related"}
+{"text":"A 66-year-old Japanese woman with severe scleroderma developed anemia and thrombocytopenia due to D-penicillamine (D-Pen) treatment, although the leukopenia was not markedly severe.","label":1,"label_text":"Related"}
+{"text":"This case reminds physicians to correlate the ancillary study results with the patient's clinical presentation and stability.","label":0,"label_text":"Not-Related"}
+{"text":"The calculated index (posterior tibial\/arm pressure) increased from a mean of 0.22 to 0.74 during the eight-month period following discontinuance of methysergide therapy with no recurrence of migraine headaches.","label":0,"label_text":"Not-Related"}
+{"text":"Fulminant Pneumocystis carinii pneumonia in 4 patients with dermatomyositis.","label":0,"label_text":"Not-Related"}
+{"text":"However, the evidence is limited and studies have not assessed the outcome of a direct substitution in these cyclosporine-dependent patients.","label":0,"label_text":"Not-Related"}
+{"text":"Parenteral-verapamil-induced sustained hypotension.","label":1,"label_text":"Related"}
+{"text":"A case of recurrent Candida parapsilosis prosthetic valve endocarditis: cure by medical treatment alone.","label":0,"label_text":"Not-Related"}
+{"text":"Nifedipine may induce, or aggravate, pre-existing, gastro-oesophageal reflux.","label":1,"label_text":"Related"}
+{"text":"We report a patient with pulmonary adenocarcinoma complicated by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) following systemic chemotherapy with cisplatin (CDDP) and vindesine (VDS).","label":1,"label_text":"Related"}
+{"text":"Two patients with ovarian cancer who had received multiple courses of cisplatin without complications experienced hypersensitivity reactions to cisplatin: one, involving intrahepatic artery infusion, manifested general erythema, dyspnea, and hypotension; the other, involving intravenous infusion, manifested abdominal pain, general erythema, and fever.","label":1,"label_text":"Related"}
+{"text":"The cause of the death was Myelodysplastic syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of high-dose intrathecal morphine overdose.","label":0,"label_text":"Not-Related"}
+{"text":"Implicated triggering factors are numerous and include toxins, medications, and infectious agents.","label":0,"label_text":"Not-Related"}
+{"text":"Diagnosis is made by clinical suspicion and exclusion of other causes of respiratory compromise.","label":0,"label_text":"Not-Related"}
+{"text":"She had undergone oral sex steroid therapy for long-term oligomenorrhea.","label":0,"label_text":"Not-Related"}
+{"text":"This report presents a 35-year-old woman in whom an intrathecal pump system was inserted for cancer pain management with intrathecal morphine.","label":0,"label_text":"Not-Related"}
+{"text":"After discontinuance of infliximab infusions and treatment of symptoms with intermittent courses of prednisone, the patient's arthritis progressively improved, with accompanying decrements in autoantibody titers.","label":0,"label_text":"Not-Related"}
+{"text":"At presentation, all patients were presumed to have classic DLK and were treated initially with aggressive topical steroids.","label":0,"label_text":"Not-Related"}
+{"text":"Mantle cell, diffuse large B-cell lymphoma and chronic lymphocytic leukaemia were diagnosed 1-5 years after PEG-rHuMGDF exposure among three volunteers.","label":0,"label_text":"Not-Related"}
+{"text":"Drug-induced ocular pemphigoid has been reported to occur after long-term use of topical glaucoma medications.","label":0,"label_text":"Not-Related"}
+{"text":"After therapy for diabetic coma with insulin (containing the preservative cresol) and electrolyte solutions was started, the patient complained of increasing myalgia, developed a high fever and respiratory and metabolic acidosis and lost consciousness.","label":1,"label_text":"Related"}
+{"text":"Fifteen such patients were treated with clozapine and rerated blind to baseline symptomatology and functional level from 2 to 9 months after beginning treatment (mean = 4.2 +\/- 2.1).","label":0,"label_text":"Not-Related"}
+{"text":"The incidence of oral-verapamil-induced hypotension in the presence of concomitant beta-adrenergic blockade by the oral route is quite rare.","label":1,"label_text":"Related"}
+{"text":"The only residual neuroblastoma tissue visible on MIBG scintigraphy on day 150 of treatment was a metastasis in the left tibia which was irradiated with 24 Gy.","label":0,"label_text":"Not-Related"}
+{"text":"The next day similar symptoms developed with rechallenge of the same brand of sustained-release verapamil in a 120-mg formulation, and verapamil was discontinued.","label":0,"label_text":"Not-Related"}
+{"text":"During the past decade, NTX has been shown to be safe and effective in the treatment of pruritus associated with severe jaundice caused by severe and sometimes life-threatening cirrhosis and other liver diseases.","label":0,"label_text":"Not-Related"}
+{"text":"Adding low-dose antidepressants to interferon alpha treatment for chronic hepatitis C improved psychiatric tolerability in a patient with schizoaffective psychosis.","label":0,"label_text":"Not-Related"}
+{"text":"We report a patient who developed heparin associated thrombocytopenia during continuous arteriovenous haemofiltration and discuss its implications and alternative anticoagulant treatment.","label":1,"label_text":"Related"}
+{"text":"Hereditary angio-oedema is rare and potentially life-threatening, being characterised by recurrent episodes of perioral or laryngeal oedema.","label":0,"label_text":"Not-Related"}
+{"text":"Subsequently, she developed bilateral persistent corneal epithelial defects, epithelial edema, and bullae that failed to heal with bandage contact lens and topical lubricants.","label":0,"label_text":"Not-Related"}
+{"text":"A case report and review of the literature.","label":0,"label_text":"Not-Related"}
+{"text":"Acute leukaemia during tamoxifen therapy.","label":1,"label_text":"Related"}
+{"text":"Human immunodeficiency virus-1 viral load and antibodies were also negative.","label":0,"label_text":"Not-Related"}
+{"text":"The most common therapeutic intervention was supportive care alone (48% of patients).","label":0,"label_text":"Not-Related"}
+{"text":"Surgeons and physicians should therefore be aware of the potential for RTA to occur with FK506 after any organ transplantation.","label":1,"label_text":"Related"}
+{"text":"He was treated as a case of sympathetically mediated chest pain, pain modulators, analgesics and Stellate ganglion block.","label":0,"label_text":"Not-Related"}
+{"text":"MATERIALS AND METHODS: We describe a patient who sustained a parotid duct injury after Mohs micrographic surgery for treatment of squamous cell carcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"It would therefore seem prudent to monitor red and white blood cell counts in patients taking MMF.","label":0,"label_text":"Not-Related"}
+{"text":"Negligible reactivity was observed with microsomes from human B-lymphoblastoid cell lines expressing CYP1A1, 1A2, 2A6, 2D6, 2E1, 3A4 or epoxide hydrolase.","label":0,"label_text":"Not-Related"}
+{"text":"The case of a 37-year-old obese man, who rapidly developed features of this syndrome after an antecedent pharyngitis and cellulitis, is presented.","label":0,"label_text":"Not-Related"}
+{"text":"He began treatment with dopamine agonists bromocriptine mesylate (in 1984) and pergolide mesylate (in 1989).","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: The cases described constitute a drug-induced lupus-like syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"We describe 2 male patients, a 49-year-old with psoriatic arthritis and impaired renal function and a 43-year-old renal transplant recipient, who both sustained a marked decline in glomerular filtration rate in conjunction with a selective inhibitor of cyclooxygenase-2 (COX-2), rofecoxib.","label":1,"label_text":"Related"}
+{"text":"Biophysiological effects of Ukrain therapy in a patient with breast cancer (case report).","label":0,"label_text":"Not-Related"}
+{"text":"This case and the brief review of the literature which follows emphasize the danger of prednisone administration in patients who have asthma and a history of drug intolerance.","label":0,"label_text":"Not-Related"}
+{"text":"On CT, they were manifested as a peritoneal mass or thickening with variable shapes, including oval, round, bizarre, linear and even a molded shape due to where they were lodged, such as the pelvis and paracolic gutter.","label":0,"label_text":"Not-Related"}
+{"text":"Angioedema is more common in females and in the third decade of life.","label":0,"label_text":"Not-Related"}
+{"text":"RD is not a rare condition, but is often misdiagnosed and is potentially lethal.","label":0,"label_text":"Not-Related"}
+{"text":"Few published human data are available concerning the acute toxicity of the new antiepileptic drug oxcarbazepine of which the metabolite 10- monohydroxy derivate (MHD) is the pharmacologically effective compound.","label":0,"label_text":"Not-Related"}
+{"text":"One patient died shortly after this, whereas the second patient died of the complications of prolonged shock.","label":0,"label_text":"Not-Related"}
+{"text":"The patient had diabetic nephropathy with accompanying nephrotic syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Neurological improvement and rehabilitation potential following toxic myelopathy due to intrathecal injection of doxorubicin.","label":1,"label_text":"Related"}
+{"text":"There is potential for this side effect, and additional caution in the use of this drug should be followed.","label":0,"label_text":"Not-Related"}
+{"text":"The authors suggest that serum sodium levels be carried out before commencement of carbamazepine and caution be used in prescribing carbamazepine to patients with low or borderline low sodium values.","label":0,"label_text":"Not-Related"}
+{"text":"Itch and skin rash from chocolate during fluoxetine and sertraline treatment: case report.","label":1,"label_text":"Related"}
+{"text":"Proctoscopic examination after 10 days of therapy showed marked improvement with no evidence of pseudomembranous exudate.","label":0,"label_text":"Not-Related"}
+{"text":"The potential development of SJS\/TEN, a severe life-threatening illness, emphasizes the need for judicious use of TMP-Sx and close monitoring and follow-up for patients who were given TMP-Sx for SSTIs.","label":1,"label_text":"Related"}
+{"text":"In the double-blind trial, 1 patient (12.5%) receiving rhEPO responded, as compared with no responses in the placebo group.","label":0,"label_text":"Not-Related"}
+{"text":"Clinical, laboratory, serologic, and histologic data of all three cases were analyzed.","label":0,"label_text":"Not-Related"}
+{"text":"Cardiac transplantation under new legislation for organ transplantation in Japan: report of two cases.","label":0,"label_text":"Not-Related"}
+{"text":"Vogt-Koyanagi-Harada disease occurring during interferon alpha therapy for chronic hepatitis C.","label":1,"label_text":"Related"}
+{"text":"Serum antidiuretic hormone (ADH) remained elevated at 0.59 pg\/ml in spite of a significant reduction in serum osmolality to 254 mosm\/kg.","label":0,"label_text":"Not-Related"}
+{"text":"One year after undergoing allogenic peripheral blood stem cell transplantation (PBSCT), this patient presented with proteinuria.","label":0,"label_text":"Not-Related"}
+{"text":"Gemcitabine-induced pulmonary toxicity is usually a dramatic condition.","label":1,"label_text":"Related"}
+{"text":"Reported here is an unusual case of radiation enteritis which caused a severe sequelae of stricture in the transverse colon as a long-term effect of therapeutic irradiation for uterine cancer, and required a surgical resection.","label":0,"label_text":"Not-Related"}
+{"text":"Body temperature was reduced to 26 degrees C and rhabdomyolysis due to hypothermia was observed.","label":0,"label_text":"Not-Related"}
+{"text":"Flecainide is a rare cause of hypersensitivity pneumonitis, and few cases have been reported.","label":1,"label_text":"Related"}
+{"text":"The histology of these lesions is characterized by intravascular thrombi.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case in which transient sinus arrest was observed under general anesthesia.","label":0,"label_text":"Not-Related"}
+{"text":"Ballistic movements due to ischemic infarcts after intravenous heroin overdose: report of two cases.","label":1,"label_text":"Related"}
+{"text":"Neurotoxicity of valacyclovir in peritoneal dialysis: a pharmacokinetic study.","label":1,"label_text":"Related"}
+{"text":"He was treated with intravenous antibiotics for 6 weeks with continuation of his immunosuppression.","label":0,"label_text":"Not-Related"}
+{"text":"It may vary in both presenting characteristics and severity.","label":0,"label_text":"Not-Related"}
+{"text":"We report here the case of a 36-year-old man with pre-B cell acute lymphoblastic leukemia.","label":0,"label_text":"Not-Related"}
+{"text":"Five of these six patients had renal failure.","label":0,"label_text":"Not-Related"}
+{"text":"Recent data in animal studies have indicated that olanzapine and clozapine rapidly impair whole-body insulin sensitivity in a dose-dependent manner.","label":0,"label_text":"Not-Related"}
+{"text":"Use of heliox for intraoperative bronchospasm: a case report.","label":0,"label_text":"Not-Related"}
+{"text":"Lenalidomide is an important contemporary treatment option for patients with multiple myeloma (MM).","label":0,"label_text":"Not-Related"}
+{"text":"The uneventful recovery seen in these patients shows the advances made in transplant medicine, including the progress and improvement of immunosuppressive therapy, surgical techniques, myocardial protection, and detection and treatment of infection.","label":0,"label_text":"Not-Related"}
+{"text":"Persistent ileus was treated with repeated doses of neostigmine, and gastrointestinal motility returned with prompt defecation.","label":0,"label_text":"Not-Related"}
+{"text":"The authors intend to carry out a case-control study on patients treated with tamoxifen for breast carcinoma to reveal the possible presence of endometrial carcinoma.","label":1,"label_text":"Related"}
+{"text":"METHODS: A 68-year-old man developed intense conjunctival hyperemia and cystoid macula edema after switching from latanoprost to bimatoprost 9 months after cataract surgery in an eye at low-risk for this cystoid macular edema.","label":1,"label_text":"Related"}
+{"text":"RESULTS-A gross mass of hyperplasia tissue found primarily in the left side of her mouth had disappeared and serum IgA which was subnormal at the first visit had normalized.","label":0,"label_text":"Not-Related"}
+{"text":"Diagnosis of pseudotumor cerebri was based on satisfaction of four criteria proposed by Ahlskog and O'Neill.","label":0,"label_text":"Not-Related"}
+{"text":"Immunohistochemical analysis of tongue biopsies confirmed the suspicion of melanin deposits in these areas of hyperpigmentation.","label":0,"label_text":"Not-Related"}
+{"text":"Possible mechanisms for this observation and clinical guidelines to identify patients at risk are suggested.","label":0,"label_text":"Not-Related"}
+{"text":"The diffuse use of cholinesterase inhibitors in the treatment of dementia may cause an increasing number of Pisa syndrome cases.","label":0,"label_text":"Not-Related"}
+{"text":"During his evaluation for right upper quadrant pain an abnormal liver scan demonstrated what proved to be a hypervascular hepatic lesion.","label":0,"label_text":"Not-Related"}
+{"text":"The uncomplicated long-term use of adequately-dosed AZA and stable non-toxic metabolite levels could not acknowledge TPMT deficiency as a primary cause of the leukopenia.","label":1,"label_text":"Related"}
+{"text":"Cholesterol crystal embolization-associated renal failure after therapy with recombinant tissue-type plasminogen activator.","label":1,"label_text":"Related"}
+{"text":"METHODS: A patient with C6D tetraplegia who sustained intoxication because of drug interaction is presented.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: PRES is a rare syndrome that must be suspected in every patient presenting neurologic symptoms in the course of immunosuppression.","label":0,"label_text":"Not-Related"}
+{"text":"The following case demonstrates marked improvement in treatment-resistant RSD pain with intramuscular ketorolac.","label":0,"label_text":"Not-Related"}
+{"text":"Virilizing adrenal tumor in a child suppressed with dexamethasone for three years.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Drug toxicological screening is commonly used as a diagnostic tool in patients with suspected toxic ingestion.","label":0,"label_text":"Not-Related"}
+{"text":"S-1 could be used as palliative treatment in patients with recurrent\/metastatic head and neck cancer.","label":0,"label_text":"Not-Related"}
+{"text":"Two years later, 24 hours following an increase in the dose of disopyramide from 300 to 600 mg\/day, AVT with syncope occurred; isoproterenol abolished the arrhythmia instantly.","label":1,"label_text":"Related"}
+{"text":"No adverse effects attributable to therapy were identified.","label":0,"label_text":"Not-Related"}
+{"text":"It is a dibenzothiazepine derivative and shows similarities with clozapine in that it is characterized by high 5-HT(2)-relative-to-DA(2) receptor affinity.","label":0,"label_text":"Not-Related"}
+{"text":"Though hypotension, dry mouth, and constipation are well-documented possible adverse effects, the possibility of clonidine-induced bradycardia is less well recognized and is rare.","label":1,"label_text":"Related"}
+{"text":"Documentation of adverse events for safe and commonly used drugs is important.","label":0,"label_text":"Not-Related"}
+{"text":"After 4 weeks, the necrotic tissue sloughed off, the early signs of healing appeared making surgical debridement possible.","label":0,"label_text":"Not-Related"}
+{"text":"We report here on two middle-aged women, apparently healthy, who suffered from a fatal intracerebral hemorrhage following a dental treatment.","label":0,"label_text":"Not-Related"}
+{"text":"No recurrence of clinical signs occurred during the follow-up period (1 and 4 years, respectively).","label":0,"label_text":"Not-Related"}
+{"text":"A diagnosis of neuroleptic malignant syndrome was made and the patient continued to receive aggressive supportive care.","label":0,"label_text":"Not-Related"}
+{"text":"Growth hormone insufficiency in a girl with the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.","label":0,"label_text":"Not-Related"}
+{"text":"In the present study, arsenic trioxide was given intravenously for 42 days to a 56-year-old female patient suffering from chemotherapy\/ATRA-resistant APL, with 43% APL blasts in the bone marrow and elevated D-dimers.","label":0,"label_text":"Not-Related"}
+{"text":"Once ACAD has been established, treatments such as coronary angioplasty, coronary stenting, and coronary bypass are performed.","label":0,"label_text":"Not-Related"}
+{"text":"The authors discuss the potential synergistic effects of these drugs and recommend treatment with propranolol.","label":0,"label_text":"Not-Related"}
+{"text":"Free SDCs were obtained using an ultrafiltration and fluorescence polarization immunoassay system in three patients over periods of up to 204 hours after Fab administration.","label":0,"label_text":"Not-Related"}
+{"text":"Thrombosis of prosthetic cardiac valves is a rare but potentially lethal complication.","label":0,"label_text":"Not-Related"}
+{"text":"Re-do surgery remains indicated for all other cases of prosthetic malfunction.","label":0,"label_text":"Not-Related"}
+{"text":"Controversy concerning the nephrotoxicity of lithium is discussed, and recommendations for the evaluation of renal failure during lithium therapy are provided.","label":1,"label_text":"Related"}
+{"text":"Leprechaunism is an autosomal recessive disease characterized by elfin-like faces, loss of glucose homeostasis, and severe insulin resistance.","label":0,"label_text":"Not-Related"}
+{"text":"Cosmetic permanent fillers for soft tissue augmentation: a new contraindication for interferon therapies.","label":0,"label_text":"Not-Related"}
+{"text":"No neurological deficit was detected despite prolonged hypoxemia.","label":0,"label_text":"Not-Related"}
+{"text":"On the other hand, CLL could precede, but could also be diagnosed at the same, or delayed time as AML, suggesting the presence of other leukemogenic factors.","label":0,"label_text":"Not-Related"}
+{"text":"A case of anaphylactoid reaction due solely to the use of Gelofusine in a patient with non-haemorrhagic hypovolaemia is presented, with a discussion on the management and the use of allergy identification jewellery.","label":1,"label_text":"Related"}
+{"text":"The expected number of AML\/MDS developing in a general population of the same size was 1.2 as calculated from the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) Program data (observed-to-expected ratio = 2.49; 95% confidence interval = 0.9-7.3; p = 0.12).","label":0,"label_text":"Not-Related"}
+{"text":"To the best of our knowledge, this is the first case report of pelvic dyskinesia with good evolution and control of dyskinesias after treatment with tetrabenazine.","label":0,"label_text":"Not-Related"}
+{"text":"He was treated by the administration of vancomycin, fluconazole, and pazufloxacin mesilate.","label":0,"label_text":"Not-Related"}
+{"text":"Linezolid-associated acute interstitial nephritis and drug rash with eosinophilia and systemic symptoms (DRESS) syndrome.","label":1,"label_text":"Related"}
+{"text":"A case is described of a life threatening vasculitis of the small bowel leading to massive gastrointestinal haemorrhage which was apparently due to cytomegalovirus inclusion disease.","label":0,"label_text":"Not-Related"}
+{"text":"We also discuss (in the format of questions and answers) the pathophysiological mechanisms underlying the association of serum uric acid with cardiovascular disease, and we review the relevant literature to justify an evidence-based decision to choose an antihypetensive agent (losartan) or a lipid-lowering drug (fenofibrate) with an additional hypouricaemic effect.","label":0,"label_text":"Not-Related"}
+{"text":"He has remained clinically stable for over 5 years.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of HCL in a 66-year-old male treated with 2-deoxycoformycin.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was a 24-years-old male referred to the OPD Clinic at Zare Psychiatry Hospital in 2007 with symptoms of delusion of control, delusion of persecution, delusion of somatic and auditory hallucination, for the last year.","label":0,"label_text":"Not-Related"}
+{"text":"A diagnosis of severe lithium toxicity was made and the patient was admitted to the telemetry unit.","label":0,"label_text":"Not-Related"}
+{"text":"The treatment with leflunomide was suspended; the conditions of the patient gradually improved and he became completely asymptomatic 1 week later.","label":0,"label_text":"Not-Related"}
+{"text":"There is no case of acute bilateral parotitis reported previously with i.v. enalaprilat.","label":0,"label_text":"Not-Related"}
+{"text":"The clinical picture and radiological abnormalities disappeared spontaneously on discontinuation of the drug.","label":0,"label_text":"Not-Related"}
+{"text":"The onset of this endocrine syndrome appeared to coincide with a more aggressive phase of the course of small cell carcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"Laparoscopic splenectomy was performed before therapy in four patients with platelet counts of <70,000\/mm(3), and during therapy in five patients with severe thrombocytopenia.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Sympathomimetic-related intracerebral hemorrhage is well-documented.","label":0,"label_text":"Not-Related"}
+{"text":"CASE REPORT: Forty years oriented old male, opium addict, was admitted to the ICU, with headache, nausea and abdominal pain, and weakness in his lower and upper extremities without definitive diagnosis.","label":0,"label_text":"Not-Related"}
+{"text":"However, one patient exhibited severe hypersensitivity reactions including cardiac arrest and apnea, and another four patients developed eruptions, hypotension, and tachycardia soon after administration of CBDCA.","label":1,"label_text":"Related"}
+{"text":"A 74-year-old hypercholestrerolaemic woman taking cerivastatin (0.15 mg\/day) for 22 days complained of general muscle weakness and muscle pain.","label":1,"label_text":"Related"}
+{"text":"We confirmed FH deficiency in a 30-month-old boy with recurrent HUS of 2 years duration, and attempted an auxiliary partial orthotopic liver transplantation (APOLT) to overcome the sustained intractable dependency on plasma therapy.","label":0,"label_text":"Not-Related"}
+{"text":"The diagnosis was made by isolation of the organism only after surgical drainage was established and appropriate tissues were cultured.","label":0,"label_text":"Not-Related"}
+{"text":"Clinical trials have shown that atypical drugs such as sertindole do not induce EPS, are effective against negative as well as positive symptoms and do not affect cognition.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: The administration of tissue plasminogen activator was responsible for the large extent of hemorrhage and should be considered in the differential diagnosis of hemorrhagic choroidal detachment.","label":1,"label_text":"Related"}
+{"text":"HIV1 and HIV2 serology was negative.","label":0,"label_text":"Not-Related"}
+{"text":"We report a rare case of colonic mucosal necrosis following Kalimate (calcium polystryrene sulfonate), an analogue of Kayexalate without sorbitol in a 34-yr-old man.","label":1,"label_text":"Related"}
+{"text":"The scavenging properties of N-AC may palliate and possibly prevent free radical-mediated liver damage.","label":0,"label_text":"Not-Related"}
+{"text":"A young male presented with acute cervico-facial swelling and loss of consciousness, following ingestion of barracuda flesh.","label":0,"label_text":"Not-Related"}
+{"text":"No respiratory symptoms appeared in the ten patients who were given less than 950 mg\/m2.","label":0,"label_text":"Not-Related"}
+{"text":"Various probe drugs may be used for phenotyping CYP2D6 (debrisoquine, dextromethorphan and sparteine) and CYP2C19 (mephenytoin and omeprazole).","label":0,"label_text":"Not-Related"}
+{"text":"The pharmaceutical company producing Halfan has reported 8 cardiac arrests, leading to 6 deaths, when a higher dose than recommended was used, there was recent or concomitant treatment with mefloquine, there was pre-existing prolongation of the QT interval or the patient had a thiamine deficiency.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: Early recognition of this serious pharmacogenetic syndrome may allow for the modification of future chemotherapy, thus avoiding further life-threatening toxicities.","label":0,"label_text":"Not-Related"}
+{"text":"His illness was also characterized by a palpable spleen tip, marked lower extremity and scrotal edema, and generalized lymphadenopathy.","label":0,"label_text":"Not-Related"}
+{"text":"This case of embolism into bone due to GEE is a rare complication which indisputably establishes a link between the spontaneously septic cavity of the bowel and bone tissue by way of blood via the interstices of the fabric.","label":0,"label_text":"Not-Related"}
+{"text":"The anti-epileptic agent trimethadione was given orally to 30 outpatients at a dose of 0.9-1.5 g daily.","label":0,"label_text":"Not-Related"}
+{"text":"Following diagnostic laparotomy she received intra-arterial 'lipiodolized' chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"This procedure appears to be a simple, safe, and effective method for closure of a small conjunctival break.","label":0,"label_text":"Not-Related"}
+{"text":"In addition to the chemotherapy, other factors known to be capable of producing RML, such as sepsis, other medications, and dehydration were found.","label":0,"label_text":"Not-Related"}
+{"text":"A 32-year-old primigravida was admitted because of premature labor at 31 weeks of gestation.","label":0,"label_text":"Not-Related"}
+{"text":"Pirmenol hydrochloride-induced QT prolongation and T wave inversion on electrocardiogram during treatment for symptomatic atrial fibrillation.","label":1,"label_text":"Related"}
+{"text":"He became hyperkalemic on rechallenge with timolol and normokalemic following its withdrawal.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND: Gemcitabine has mild renal toxicity, but cases of gemcitabine-associated hemolytic-uremic syndrome (HUS) have been reported.","label":1,"label_text":"Related"}
+{"text":"We describe a unique case of disseminated cryptococcosis presenting as colitis that mimicked an exacerbation of Crohn's disease in a TNF-alpha inhibitor recipient.","label":0,"label_text":"Not-Related"}
+{"text":"Two of them could not be considered primary: in one the pain was related to an underlying, pointed and benign lesion disclosed only by magnetic resonance imaging (case 1); the second one had persistent NH days after trans-sphenoidal surgery for a pituitary adenoma, similar to a postcraniotomy headache (case 2).","label":0,"label_text":"Not-Related"}
+{"text":"It is common practice in critical care areas for registered nurses to administer antiarrhythmics without a doctor's prescription in life-threatening situations.","label":0,"label_text":"Not-Related"}
+{"text":"Although the patient recovered from her renal failure (creatinine clearance 43 ml\/min), the nephrotic syndrome persisted (13 g protein\/day).","label":0,"label_text":"Not-Related"}
+{"text":"Delayed pseudocyst of the pancreas can be a complication of intramuscular L-asparaginase.","label":1,"label_text":"Related"}
+{"text":"An early gestational insult, rather than a mutation, may be one cause of this heterogenous disorder.","label":0,"label_text":"Not-Related"}
+{"text":"The cost of the demanding lifestyle of military aircrew members and the fear of hypoglycemic episodes can result in periods of sub-optimal glucose control.","label":0,"label_text":"Not-Related"}
+{"text":"S-1 was safely administered in outpatients and showed some efficacy in the treatment of recurrent\/metastatic head and neck cancer in patients who had received previous chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Doxycycline-induced hypoglycemia in a nondiabetic young man.","label":1,"label_text":"Related"}
+{"text":"Several courses of oral voriconazole were required for resolution of the infection.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: A 37-year-old African- American man with G6PD deficiency developed hemolytic anemia, hepatitis, orthostatic hypotension, and aseptic meningitis simultaneously after using trimethoprim-sulfamethoxazole.","label":1,"label_text":"Related"}
+{"text":"These symptoms worsened over 24 hours despite discontinuation of therapy, then gradually decreased in severity but persisted until his death two months later.","label":0,"label_text":"Not-Related"}
+{"text":"The authors emphasize that this patient did not have any predisposing factors to fungal infections.","label":0,"label_text":"Not-Related"}
+{"text":"She continued to receive regular insulin 4 times per day over the following 3 years with only occasional hives.","label":1,"label_text":"Related"}
+{"text":"The most well-described presentation is diffuse lamellar keratitis (DLK), which typically develops early after LASIK and responds quickly to topical steroids.","label":0,"label_text":"Not-Related"}
+{"text":"The mechanism by which ciprofloxacin causes these adverse effects is not fully understood.","label":0,"label_text":"Not-Related"}
+{"text":"Investigation of the cause of death in a gene-therapy trial.","label":0,"label_text":"Not-Related"}
+{"text":"Pustular psoriasis elicited by streptococcal antigen and localized to the sweat pore.","label":0,"label_text":"Not-Related"}
+{"text":"In North America, the adult tapeworm of Taenia (Multiceps) serialis is found in canids.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: Two case reports.","label":0,"label_text":"Not-Related"}
+{"text":"Overall, there were no relevant changes in clinical ratings including adverse effects.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To report 2 cases of serotonin syndrome with serious extrapyramidal movement disorders occurring when metoclopramide was coadministered with sertraline or venlafaxine.","label":1,"label_text":"Related"}
+{"text":"The influence of diuretic therapy in combination with lithium is felt to enhance the risk of intoxication.","label":0,"label_text":"Not-Related"}
+{"text":"Warfarin resistance and enteral feedings.","label":0,"label_text":"Not-Related"}
+{"text":"The presence of olanzapine was confirmed by gas chromatography-mass spectrometry by use of electron impact ionization.","label":0,"label_text":"Not-Related"}
+{"text":"Three relevant cases are reported and a review of the published literature is made.","label":0,"label_text":"Not-Related"}
+{"text":"Teicoplanin-induced agranulocytosis that followed vancomycin-induced agranulocytosis suggests a possible cross-reactivity between the 2 drugs.","label":1,"label_text":"Related"}
+{"text":"A 58-year-old woman with rheumatoid arthritis (RA) developed fever, skin eruptions, leukocytopenia, and thrombocytopenia, 3 weeks after treatment with sulfasalazine.","label":1,"label_text":"Related"}
+{"text":"Our data is consistent with the notion that elevated blood levels of PTH in patients with chronic renal failure participate in the genesis of anemia of renal failure.","label":0,"label_text":"Not-Related"}
+{"text":"Clinical notes on the possible anticholinergic reversal of depressive syndromes.","label":0,"label_text":"Not-Related"}
+{"text":"The technique of immunocytochemistry was used to identify myoglobin in kidney, confirming a diagnosis of neuroleptic malignant syndrome following an otherwise obscure autopsy in a decomposed body.","label":0,"label_text":"Not-Related"}
+{"text":"The first signs of joint manifestations started one year after HIV seroconversion and resolved when antiviral treatment with AZT was started.","label":0,"label_text":"Not-Related"}
+{"text":"Methemoglobinemia after axillary block with bupivacaine and additional injection of lidocaine in the operative field.","label":1,"label_text":"Related"}
+{"text":"Before starting Zoledronic acid therapy, the patient's serum calcium level was 6.9 mg\/dl.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of a woman who developed photo-onycholysis on multiple nails after uptake of olanzapine.","label":1,"label_text":"Related"}
+{"text":"Previous studies showed that clevudine has potent and sustained antiviral activity without causing viral resistance.","label":0,"label_text":"Not-Related"}
+{"text":"Serum liver tests showed a mean total bilirubin of 1.4 +\/- .7 mg\/dL (range, .5-2.5) and INR was 1.2 +\/- .14 (range, 1.0-1.4).","label":0,"label_text":"Not-Related"}
+{"text":"Treatment of APL in pregnancy is controversial as the use of ATRA has been questioned due to the teratogenic effect of retinoids.","label":1,"label_text":"Related"}
+{"text":"Profound hypoxemia during treatment of low cardiac output after cardiopulmonary bypass.","label":0,"label_text":"Not-Related"}
+{"text":"The case was unusual in the rapidity and magnitude of hepatic enzyme elevation.","label":0,"label_text":"Not-Related"}
+{"text":"This article presents a patient with hypoparathyroidism who was treated with calcium carbonate and calcitriol resulting in two admissions to the hospital for milk-alkali syndrome.","label":1,"label_text":"Related"}
+{"text":"A bone marrow biopsy did not show signs of hematologic disease, but revealed a small granuloma rife with acid-fast bacilli, which were later confirmed to be Mycobacterium genavense by gene sequencing.","label":0,"label_text":"Not-Related"}
+{"text":"Lithium toxicity in a neonate.","label":0,"label_text":"Not-Related"}
+{"text":"According to the Naranjo adverse drug reaction probability scale, cesium was the probable cause of the patient's arrhythmia.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was given combined antibiotics and the abscess drained surgically.","label":0,"label_text":"Not-Related"}
+{"text":"Combined clozapine and electroconvulsive therapy for the treatment of drug-induced psychosis in Parkinson's disease.","label":0,"label_text":"Not-Related"}
+{"text":"A case report.","label":0,"label_text":"Not-Related"}
+{"text":"The presence of a myopathy could render this patient susceptible to the respiratory effects of opioids.","label":0,"label_text":"Not-Related"}
+{"text":"Transient left homonymous hemianopsia and encephalopathy following treatment of testicular carcinoma with cisplatinum, vinblastine, and bleomycin.","label":1,"label_text":"Related"}
+{"text":"With improved treatment and outcome of lupus, an increasing number of elderly patients who are susceptible to osteoporotic fractures are expected.","label":0,"label_text":"Not-Related"}
+{"text":"Our case report is focused on a woman receiving hemodialysis (HD) with diabetes mellitus for 20 years and severe secondary hyperparathyroidism, who presented painful subcutaneous nodules, skin necrosis and ulcerations.","label":0,"label_text":"Not-Related"}
+{"text":"In this report we describe a patient with hyperthyroidism whose symptoms initially were thought to be adverse effects of the inhaled bronchodilator medications.","label":0,"label_text":"Not-Related"}
+{"text":"Severe hepatotoxicity from phenobarbital occurred in an infant boy who had a complicated illness with chronic bilateral subdural hematomas and sepsis.","label":1,"label_text":"Related"}
+{"text":"The overall rate of avascular necrosis in Crohn's disease was less than 0.5% but for men with Crohn's disease was about 1%.","label":0,"label_text":"Not-Related"}
+{"text":"Clofazimine enteropathy caused by crystal deposition can be life-threatening.","label":1,"label_text":"Related"}
+{"text":"However, double-blind, placebo-controlled studies are necessary to confirm these preliminary results.","label":0,"label_text":"Not-Related"}
+{"text":"However, this report suggests that a further endoscopic intervention may be necessary in case the dissolved bezoars cause small-bowel obstruction during this form of therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Pentazocine-induced fibrous myopathy and localized neuropathy.","label":1,"label_text":"Related"}
+{"text":"A 9-year-old girl with AIDS was brought to the emergency department because of tetany.","label":0,"label_text":"Not-Related"}
+{"text":"Peripheral neuropathy was not fully reversed in all patients.","label":0,"label_text":"Not-Related"}
+{"text":"We herein described an additional patient with BCR-ABL (ela2) positive acute lymphoblastic leukemia who developed tumor lysis syndrome after 10-day treatment with imatinib.","label":1,"label_text":"Related"}
+{"text":"A previous review described data on 15 patients who experienced acute hemoglobinemia or hemoglobinuria following anti-D IGIV administration for ITP or secondary thrombocytopenia.","label":1,"label_text":"Related"}
+{"text":"A few cases of severe skin reactions such as toxic epidermal necrolysis have been reported.","label":0,"label_text":"Not-Related"}
+{"text":"Sorafenib induced tumor lysis syndrome in an advanced hepatocellular carcinoma patient.","label":1,"label_text":"Related"}
+{"text":"In two patients, aprotinin infusion was added to heparin to treat bleeding, occurring after few days of bypass and responsible for respiratory and hemodynamic deterioration.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Metastatic renal cell carcinoma (MRCC) has been characteristically unresponsive to chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"It is well known that exposure to manganese, solvents, or carbon monoxide in an occupational setting may lead to central nervous system damage and parkinsonism.","label":0,"label_text":"Not-Related"}
+{"text":"Two case histories are presented illustrating the difficulties of treating candida septicaemia.","label":0,"label_text":"Not-Related"}
+{"text":"Post-dural puncture headache, intracranial air and obstetric anesthesia.","label":0,"label_text":"Not-Related"}
+{"text":"I report a patient who developed the syndrome during treatment for schizophrenia with the antipsychotic agent molindone hydrochloride.","label":0,"label_text":"Not-Related"}
+{"text":"Acute severe intoxication with carbamazepine is associated with seizures, coma and respiratory depression.","label":1,"label_text":"Related"}
+{"text":"Furthermore, the authors provide diagnostic and treatment options that are available for mitochondrial disorders, which are of interest to child psychiatrists due to the central nervous system manifestations of these disorders.","label":0,"label_text":"Not-Related"}
+{"text":"Reversible cholestasis with bile duct injury following azathioprine therapy.","label":1,"label_text":"Related"}
+{"text":"Two months later, Pneumocystis carinii pneumonia developed.","label":0,"label_text":"Not-Related"}
+{"text":"Evaluation revealed elevated serum LTG levels and no other etiology for encephalopathy.","label":1,"label_text":"Related"}
+{"text":"We describe 2 patients with cutaneous lupus erythematosus who developed severe dapsone reaction after low dose therapy, with a fatal outcome in one.","label":1,"label_text":"Related"}
+{"text":"Three cases of pseudocyst of the pancreas in two women and one man have previously been reported with the use of intravenous L-asparaginase.","label":1,"label_text":"Related"}
+{"text":"We report 3 children with epilepsy who developed facial motor tics after initiation of CBZ for complex partial seizures.","label":1,"label_text":"Related"}
+{"text":"Tests for antimyeloperoxidase ANCA were repeatedly negative before the drug was started, strongly implicating the drug as the cause of the episode.","label":0,"label_text":"Not-Related"}
+{"text":"It is important for oncologists to recognize this complication and prevent its development if bulky metastatic disease and several pre-existing risk factors, such as multiple and bulky liver metastases, elevated lactate dehydrogenase, and hyperuricemia, are present.","label":0,"label_text":"Not-Related"}
+{"text":"This medicine is available without prescription and contains the potent oxidant ethyl nitrite.","label":0,"label_text":"Not-Related"}
+{"text":"Systemic lupus erythematosus (SLE) was suspected as a possible etiologic or modifying cofactor in TEN in this case.","label":0,"label_text":"Not-Related"}
+{"text":"This observation questions the suitability of aspirin as prophylaxis for vascular disease in patients with meningiomas.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment possibilities of this multisystem disease up to now remain disappointing.","label":0,"label_text":"Not-Related"}
+{"text":"Moreover, antibody therapy does not take effect immediately, as is understandable in view of the mechanism of action.","label":0,"label_text":"Not-Related"}
+{"text":"The prognosis of t-MDS is generally poor.","label":0,"label_text":"Not-Related"}
+{"text":"Several responses and 2 complete remissions occurred.","label":0,"label_text":"Not-Related"}
+{"text":"A review of the literature regarding the pathogenicity of this organism and, in particular, its occurrence as a cause of pneumonia is presented.","label":0,"label_text":"Not-Related"}
+{"text":"We report an unusual case of simultaneous transitional cell carcinoma of the renal pelvis and distal ureter without transitional cell carcinoma of the bladder occurring after chronic cyclophosphamide therapy for nonHodgkin's lymphoma.","label":1,"label_text":"Related"}
+{"text":"Immune thrombocytopenic purpura (ITP) was diagnosed, and she was treated with 40 mg of methylprednisolone per day for 19 days.","label":0,"label_text":"Not-Related"}
+{"text":"Although neurotoxicity is a frequent complication of methotrexate therapy, fatal acute neurotoxicity is extremely uncommon, especially in adults.","label":1,"label_text":"Related"}
+{"text":"Management of toxic epidermal necrolysis in a 15-year-old girl.","label":0,"label_text":"Not-Related"}
+{"text":"The sorrow of mistakes has been expressed as the too-lateness of human understanding as it lies along the continuum of time, and as a wish that it might have been different, both then and now\" (p.149).","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION Inhibition of mTORC1, pathologically activated by loss of the TSC1\/TSC2 tumor suppressor complex, is a rational mechanistic target for therapy in PEComas.","label":0,"label_text":"Not-Related"}
+{"text":"This case report describes an adolescent with severe lupus erythematosus who received cyclophosphamide (CY) paired with taste (cod liver oil) and smell (rose perfume) as conditioned stimuli.","label":1,"label_text":"Related"}
+{"text":"Severe transplacental lithium toxicity in a neonate is described.","label":0,"label_text":"Not-Related"}
+{"text":"Analyzing the cardiac time intervals during pregnancy can improve perinatal outcome.","label":0,"label_text":"Not-Related"}
+{"text":"METHOD: Case analysis of a poly-drug overdose (venlafaxine, topiramate, divalproex sodium, risperidone, and carbamazepine) presenting with mixed SS\/NMS features and whose clinical management suggests a practical algorithm for treatment of undifferentiated SS\/NMS in critical care settings.","label":1,"label_text":"Related"}
+{"text":"Nonspecific but significant abnormalities have been described in the infants of women treated with disulfiram in the first trimester of their pregnancies.","label":1,"label_text":"Related"}
+{"text":"Anticoagulant theraphy was started.","label":0,"label_text":"Not-Related"}
+{"text":"Because of a hypersensitivity reaction, initial therapy with penicillin G and gentamicin was stopped and substituted with cefazolin.","label":1,"label_text":"Related"}
+{"text":"Research has shown that atypical antipsychotic also reduce the craving and consumption for stimulants and alcohol.","label":0,"label_text":"Not-Related"}
+{"text":"She was receiving phenytoin sodium 300 mg\/day; carbamazepine 200 mg four times daily had been discontinued four days before admission because of leukopenia.","label":1,"label_text":"Related"}
+{"text":"Two months after the transplant she developed an interstitial pneumonia: bronchoalveolar lavage yielded cytomegalic cells with intranuclear bodies, and cytomegalovirus DNA was detected by in situ hybridization techniques.","label":0,"label_text":"Not-Related"}
+{"text":"He received 174 gm of intravenous calcium for total of 12 days.","label":0,"label_text":"Not-Related"}
+{"text":"Steroids were given promptly on the day following onset of pneumonitis, and the patient (72 years old) recovered almost completely within one and a half months.","label":0,"label_text":"Not-Related"}
+{"text":"However, it also highlights the importance of determining a patient's tuberculosis status, initiating prophylactic anti-tuberculosis therapy prior to starting treatment with etanercept, and setting up an adequate treatment regime if the patient develops active tuberculosis during therapy with etanercept.","label":0,"label_text":"Not-Related"}
+{"text":"In one patient this resulted in an ischemic and necrotic digital ulcus, necessitating surgical amputation.","label":0,"label_text":"Not-Related"}
+{"text":"Administration of lamotrigine, especially in combination with valproic acid, may lead to the development of TEN.","label":1,"label_text":"Related"}
+{"text":"Immunofluorescent studies showed deposits of immunoglobulins and C3 in a granular pattern in the glomerular basement membranes.","label":0,"label_text":"Not-Related"}
+{"text":"Pelvic arterial pseudoaneurysm-a rare complication of Cesarean section: diagnosis and novel treatment.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of generalized cutaneous sclerosis associated with muscle and oesophageal involvement in a patient exposed to herbicides containing bromocil, diuron and aminotriazole.","label":1,"label_text":"Related"}
+{"text":"During SIRT, (90)Y-microspheres are infused into the hepatic artery.","label":0,"label_text":"Not-Related"}
+{"text":"Phenytoin levels were measured and found to be grossly elevated at 170 mmol\/L.","label":0,"label_text":"Not-Related"}
+{"text":"Thus, clinical recognition of sleep disordered breathing should be taken into account when rheumatoid arthritis patients are to be treated with infliximab.","label":1,"label_text":"Related"}
+{"text":"When SASP was changed to 5-aminosalicylic acid (5-ASA), his skin eruptions were resolved, however, he developed weakness and atrophy in his right arm as well as progressive worsening of the dysesthesia in his legs and gait disturbance.","label":1,"label_text":"Related"}
+{"text":"A case is presented in which the catatonic-like behavior and extrapyramidal sequelae of the neuroleptic malignant syndrome responded to combined treatment with anticholinergics and levodopa\/carbidopa.","label":0,"label_text":"Not-Related"}
+{"text":"He had a low-level PVB19 load for a 5-mo follow-up period without recurrence of PRCA, and finally the virus was cleared.","label":0,"label_text":"Not-Related"}
+{"text":"Both patients were treated with low-molecular-weight heparin in addition to pre-existing ACE inhibition.","label":0,"label_text":"Not-Related"}
+{"text":"Interferon and other immunostimulatory medications can lead to an exacerbation of this preexisting low-grade chronic inflammation that is quite similar to interferon-triggered sarcoidosis.","label":0,"label_text":"Not-Related"}
+{"text":"A case of acute cardiomyopathy and pericarditis associated with methylphenidate.","label":1,"label_text":"Related"}
+{"text":"Very rarely, P. avidum causes systemic infections after invasive procedures, most notably in immunocompromised patients.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Merkel cell carcinoma is a rare and aggressive neuroendocrine skin cancer with a very low incidence in the general population.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Primary ovarian lymphoma is an extremely rare disease and limited count reports about it have been reported in the literature.","label":0,"label_text":"Not-Related"}
+{"text":"Two cases of ovarian torsion after gamete intra-Fallopian transfer are described and the roles of ovarian manipulation during the procedure, ovarian hyperstimulation and pregnancy as predisposing factors are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"Dural sinus thrombosis in children with acute lymphoblastic leukemia.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: In the past 9 years, drugs for erectile dysfunction (ED) have been increasingly prescribed for men with erectile difficulty.","label":0,"label_text":"Not-Related"}
+{"text":"An increased incidence of different malignancies associated to chronic lymphocytic leukemia (CLL) has been reported.","label":0,"label_text":"Not-Related"}
+{"text":"A 34-year-old lady developed a constellation of dermatitis, fever, lymphadenopathy and hepatitis, beginning on the 17th day of a course of oral sulphasalazine for sero-negative rheumatoid arthritis.","label":1,"label_text":"Related"}
+{"text":"Cryptococcal meningitis in a child with systemic lupus erythematosus.","label":0,"label_text":"Not-Related"}
+{"text":"We suggest that nicotinic acid was the cause of his liver disease, that this case is of particular note because of the rather short period of therapy before the onset of liver injury and the severity of the hepatic failure, and that the probable increased use of nicotinic acid for serum cholesterol control makes it especially important for physicians and their patients to be alert to the signs of hepatotoxicity.","label":1,"label_text":"Related"}
+{"text":"This case study reports the effects of a treprostinil accidental overdose in a patient with pulmonary hypertension.","label":0,"label_text":"Not-Related"}
+{"text":"Managing cardiovascular collapse in severe flecainide overdose without recourse to extracorporeal therapy.","label":1,"label_text":"Related"}
+{"text":"Of twenty other patients in our practice who received gemcitabine for refractory lymphoma without developing pericardial effusion, none had received prior direct radiation to the heart.","label":0,"label_text":"Not-Related"}
+{"text":"Carbamazepine toxicity induced by clarithromycin coadministration in psychiatric patients.","label":1,"label_text":"Related"}
+{"text":"Indolent aspergillus arthritis complicating fludarabine-based non-myeloablative stem cell transplantation.","label":1,"label_text":"Related"}
+{"text":"OBJECTIVE: To evaluate the efficacy of cyproheptadine in the management of acute intrathecal baclofen (ITB) withdrawal.","label":0,"label_text":"Not-Related"}
+{"text":"None of the patients had worsening of the respiratory status.","label":0,"label_text":"Not-Related"}
+{"text":"This patient rapidly progressed from mild neurotoxicity to fatal encephalopathy after one dose of intrathecal methotrexate during his third cycle of chemotherapy.","label":1,"label_text":"Related"}
+{"text":"We highlight the importance of having a high index of suspicion for hepatic side effects of diclofenac and emphasize the need for increased awareness of this rare but potentially serious problem.","label":0,"label_text":"Not-Related"}
+{"text":"Various toxicities have been observed during the treatment of advanced renal cell carcinoma with interferon-alpha (IFN-alpha) and\/or interleukin-2 (IL-2).","label":0,"label_text":"Not-Related"}
+{"text":"The pathogenesis of the liver changes and their possible relationship to splenomegaly and busulphan toxicity are considered.","label":0,"label_text":"Not-Related"}
+{"text":"Adrenal suppression and failure to thrive after steroid injections for periocular hemangioma.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: Two patients with exudative age-related macular degeneration were treated sequentially with an intravitreal injection of bevacizumab and developed signs of severe but painless infectious endophthalmitis 2 days later.","label":1,"label_text":"Related"}
+{"text":"Tardive dyskinesia in 2 patients treated with ziprasidone.","label":1,"label_text":"Related"}
+{"text":"CASES: \"A\" was an 8-year-old boy with attention deficit and chronic tic disorder who developed obsessive-compulsive symptoms within 2 weeks of starting risperidone.","label":1,"label_text":"Related"}
+{"text":"Foreign bodies and bezoars are commonly encountered in children.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of unintentional overdose of oral pilocarpine tablets that resulted in bradycardia, mild hypotension, and muscarinic symptoms in a patient with Sjogren's syndrome.","label":1,"label_text":"Related"}
+{"text":"Refractory hypoglycemia from ciprofloxacin and glyburide interaction.","label":1,"label_text":"Related"}
+{"text":"Brain hemorrhage is a feared complication of early anticoagulation therapy in patients with cardioembolic brain infarction.","label":0,"label_text":"Not-Related"}
+{"text":"We describe two patients with Boerhaave's syndrome who presented with chest pain mimicking cardiac pain and received heparin therapy.","label":0,"label_text":"Not-Related"}
+{"text":"We report a girl with the Rett syndrome who had acute encephalopathy probably induced by calcium hopantenate (HOPA).","label":1,"label_text":"Related"}
+{"text":"A simple dropper that would withdraw only one drop and deliver the same would resolve this problem.","label":0,"label_text":"Not-Related"}
+{"text":"We report an unusual case of necrotizing scleritis with inflammation that occurred after strabismus surgery.","label":0,"label_text":"Not-Related"}
+{"text":"After tapering of oral prednisolone, cyclophosphamide was started, which resulted in a gradual improvement of proteinuria.","label":0,"label_text":"Not-Related"}
+{"text":"One had a mildly abnormal electro-oculogram.","label":0,"label_text":"Not-Related"}
+{"text":"She had been receiving monthly transfusions of IVIG, but this time had received daily infusions for 5 days rather than 1 day.","label":0,"label_text":"Not-Related"}
+{"text":"The authors' results suggest that L-dopa may cause daytime somnolence in some patients with Parkinson's disease.","label":1,"label_text":"Related"}
+{"text":"Surgical decompression was initially considered and then deferred in favor of observation.","label":0,"label_text":"Not-Related"}
+{"text":"In earlier studies, it was used on a daily schedule with resulting severe gastrointestinal toxicity and myelosuppression.","label":0,"label_text":"Not-Related"}
+{"text":"Finally, the most promising PD drugs that are currently in development will be reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Because of its structural similarity to the other vinca alkaloids, vinorelbine is believed to be responsible for SIADH in our patient.","label":1,"label_text":"Related"}
+{"text":"She presented with fever and mild hepatic enzyme elevations before salicylate therapy was instituted.","label":0,"label_text":"Not-Related"}
+{"text":"Dyspnea, hypoxemia, and pleuritic chest pain occurred within 24 hours of rituximab administration, and there was no other apparent explanation.","label":1,"label_text":"Related"}
+{"text":"Within the mandibular canal, the IAN runs forward in company of the inferior alveolar artery, and together they are called the inferior alveolar neurovascular bundle.","label":0,"label_text":"Not-Related"}
+{"text":"Fatal radiation myelopathy after high-dose busulfan and melphalan chemotherapy and radiotherapy for Ewing's sarcoma: a review of the literature and implications for practice.","label":1,"label_text":"Related"}
+{"text":"The last injection was immediately followed by an atrio-ventricular tachycardia with massive decrease in blood pressure.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Interferon (IFN)-associated retinopathy is typically characterized by retinal hemorrhages and cotton wool spots at the posterior fundus, but visual function is usually maintained.","label":1,"label_text":"Related"}
+{"text":"A diagnosis of infliximab-induced lupus was made and the drug treatment was withdrawn.","label":1,"label_text":"Related"}
+{"text":"Despite premedication with diphenhydramine and dexamethasone, she experienced generalized pruritus and urticaria, as well as headache and chest pain\/tightness, after her next infusion.","label":0,"label_text":"Not-Related"}
+{"text":"Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in hypertension due to primary aldosteronism: a case for exclusion.","label":0,"label_text":"Not-Related"}
+{"text":"Five months after the catheter implantation melena occurred.","label":0,"label_text":"Not-Related"}
+{"text":"There was no evidence of renal hypoperfusion or interstitial nephritis.","label":0,"label_text":"Not-Related"}
+{"text":"Therefore, bone marrow follow-up is critical for monitoring of response.","label":0,"label_text":"Not-Related"}
+{"text":"She developed edema, swelling, erythema, and vesicles on her eyelids.","label":0,"label_text":"Not-Related"}
+{"text":"His brother (age 6) and father (age 31) were also found to have elevated blood pressure.","label":0,"label_text":"Not-Related"}
+{"text":"This drug is rapidly absorbed from the gastrointestinal tract, most of which is excreted from the kidney.","label":0,"label_text":"Not-Related"}
+{"text":"Rapid onset of muscle weakness (rhabdomyolysis) associated with the combined use of simvastatin and colchicine.","label":1,"label_text":"Related"}
+{"text":"A potentially fatal ulcerating enterocolitis has been reported in 4 patients.","label":0,"label_text":"Not-Related"}
+{"text":"Lamellar inflammation was exacerbated by topical steroids.","label":0,"label_text":"Not-Related"}
+{"text":"Thrombocytosis induced by enoxaparin has been reported as a rare adverse effect of this medication in adults.","label":1,"label_text":"Related"}
+{"text":"Five patients were infected with a nontyphosal Salmonella species, Salmonella oslo.","label":0,"label_text":"Not-Related"}
+{"text":"We report herein two cases of young adult patients who were both diagnosed with Ph+ ALL 19 years after successful treatment for ES with combined modality therapy.","label":0,"label_text":"Not-Related"}
+{"text":"No other diagnostic criteria for neuroleptic malignant syndrome (NMS) were present.","label":0,"label_text":"Not-Related"}
+{"text":"Renal tubular acidosis secondary to FK506 in living donor liver transplantation: a case report.","label":1,"label_text":"Related"}
+{"text":"CASE SUMMARY: A 65-year-old patient chronically treated with the selective serotonin reuptake inhibitor (SSRI) citalopram developed confusion, agitation, tachycardia, tremors, myoclonic jerks and unsteady gait, consistent with serotonin syndrome, following initiation of fentanyl, and all symptoms and signs resolved following discontinuation of fentanyl.","label":1,"label_text":"Related"}
+{"text":"Paradoxical seizures in phenytoin toxicity.","label":1,"label_text":"Related"}
+{"text":"Wilms' tumor with transient dermolysis of the newborn: recurrence of skin lesions during chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"The patient completed a 10-month follow-up, maintaining a complete resolution of the treated skin lesions; however, the development of a painful hand ulcer, possibly associated with the hydroxyurea, and new skin cancers were observed at the last follow-up visit.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND: The treatment of colorectal cancer with administration of a 2-h infusion of calcium folinate followed by a 24-h infusion of 5-fluorouracil (5-FU) is a standard therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Upper gastrointestinal haemorrhage is a serious complication of aspirin and clopidogrel (dual) anti-platelet therapy with a high morbidity and mortality.","label":1,"label_text":"Related"}
+{"text":"The use of epidermal growth factor receptor (EGFR) inhibitors for the treatment of solid tumours is now increasing.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case histories of identical twin brothers who developed concordant acute lymphoblastic leukemia at the age of 4 years and who later developed leukoencephalopathy and hydrocephalus related to central nervous system prophylaxis by, in the first case intrathecally administered methotrexate and, in the second by intrathecally administered methotrexate and cranial irradiation.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND: Although multiple sclerosis (MS) is a common disease of the central nervous system, the association of intraparenchymal tumour has been rarely reported and the potential relationship between intracranial meningioma and MS has not been seriously analysed.","label":0,"label_text":"Not-Related"}
+{"text":"This approach might represent a promising new strategy for treatment of proteinuria after kidney transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"It has also been associated on occasion with malignancy.","label":0,"label_text":"Not-Related"}
+{"text":"Standard induction chemotherapy [cytosine arabinoside (ARA-C) and daunorubicin (DNR) for AML, vincristine (VCR), DNR and prednisone (PDN) for ALL, all-trans retinoic acid (ATRA) and DNR for APML] with the antracycline dose of at least 30 mg\/sqm were used.","label":0,"label_text":"Not-Related"}
+{"text":"A previously healthy 25-year old male with mild tonic-clonic epilepsy was found unconscious with serum VPA levels >10,000 micromol\/l.","label":0,"label_text":"Not-Related"}
+{"text":"A 14-year-old girl, dwarfed by systemic disease and long-term corticosteroid therapy, was able to discontinue prednisone and grew 6.3 cm in 11 months following 18 plasma exchanges with FFP.","label":0,"label_text":"Not-Related"}
+{"text":"Until additional data are available, if intravenous acyclovir is administered concurrently with lithium, we recommend closely monitoring patients for signs of lithium toxicity and measuring serum lithium levels every second or third day.","label":1,"label_text":"Related"}
+{"text":"Acute valproate ingestion induces symptomatic methemoglobinemia.","label":1,"label_text":"Related"}
+{"text":"Spinal artery syndrome masked by postoperative epidural analgesia.","label":0,"label_text":"Not-Related"}
+{"text":"Atypical neuroleptic malignant syndrome associated with olanzapine.","label":1,"label_text":"Related"}
+{"text":"Diffuse interstitial pneumonia and pulmonary hypertension: a novel manifestation of chronic granulomatous disease.","label":0,"label_text":"Not-Related"}
+{"text":"Initial hepatic function tests were strictly normal.","label":0,"label_text":"Not-Related"}
+{"text":"beta-Lactam therapy was initiated with vancomycin, cefepime, and metronidazole and, upon identification of methicillin-sensitive Staphylococcus aureus bacteremia 4 days later, therapy was narrowed to cefazolin 1 g every 12 hours.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: We report a case of a 33-year-old female patient who developed RPE atrophy after a single standard PDT for treatment of a juxtafoveal, predominantly classic choroidal neovascularization (CNV).","label":0,"label_text":"Not-Related"}
+{"text":"Adenosine may be of therapeutic and diagnostic value in the emergency management of arrhythmias.","label":0,"label_text":"Not-Related"}
+{"text":"The treatment of choice is liposomal amphotericin B, which failed in our patient.","label":0,"label_text":"Not-Related"}
+{"text":"Fludarabine induced lung toxicity must be considered in all patients who develop unexplained lung disease while receiving fludarabine.","label":1,"label_text":"Related"}
+{"text":"The corneal ulcer progressed despite aggressive antifungal treatment, requiring amputation of the corneal flap and daily debridement.","label":0,"label_text":"Not-Related"}
+{"text":"Therefore, thorough investigation with an ultrasound-guided aspiration followed by an early drainage of the collection is warranted and mandatory.","label":0,"label_text":"Not-Related"}
+{"text":"Patients had tended to become more neurotic (p = 0.08) and less extravert (p = 0.07).","label":0,"label_text":"Not-Related"}
+{"text":"However, in our experience, these patients are sometimes placed on angiotensin-converting enzyme (ACE) inhibitors in accordance with guidelines applying to the general hypertensive population.","label":0,"label_text":"Not-Related"}
+{"text":"Cutaneous vasculitis secondary to ramipril.","label":1,"label_text":"Related"}
+{"text":"Hypomagnesemia, hypokalemia, and hypocalcemia had developed.","label":0,"label_text":"Not-Related"}
+{"text":"Laser light was applied at a power of 400 mW\/cm fiber for a total energy of 180 J\/cm.(2) RESULTS: Fourteen treatments were performed on 6 patients with tumors of Bismuth types IV (n = 2), III (n = 3), or II (n = 1).","label":0,"label_text":"Not-Related"}
+{"text":"ARDS is rarely associated with rituximab infusion for lympho-proliferative disorders, but it should be considered by those administering rituximab, especially when a patient develops severe pulmonary symptoms soon after infusion.","label":1,"label_text":"Related"}
+{"text":"These lesions even worsened for some weeks after interruption of cabergoline, which may possibly be related to the prolonged action of this drug.","label":0,"label_text":"Not-Related"}
+{"text":"There is yet no explanation for the occurrence of hallucinations or psychosis.","label":0,"label_text":"Not-Related"}
+{"text":"The possibility of phenytoin hypersensitivity reactions should be considered when patients receiving phenytoin have unusual symptoms, particularly fever, rash, and lymphadenopathy.","label":1,"label_text":"Related"}
+{"text":"Transvenous liver biopsy revealed hepatic angiosarcoma, a rare liver tumor classically associated with environmental toxins.","label":0,"label_text":"Not-Related"}
+{"text":"Transient left homonymous hemianopsia and encephalopathy following treatment of testicular carcinoma with cisplatinum, vinblastine, and bleomycin.","label":1,"label_text":"Related"}
+{"text":"Ticlopidine-induced aplastic anemia: two new case reports, review, and meta-analysis of 55 additional cases.","label":1,"label_text":"Related"}
+{"text":"Membranous nephropathy in rheumatoid arthritis.","label":0,"label_text":"Not-Related"}
+{"text":"The patient continued to have fever and autonomic instability without evidence of infection which entirely resolved within 24 hours of reinstitution of full preadmission dosing of oral baclofen.","label":1,"label_text":"Related"}
+{"text":"Due to the more pronounced side effects of BCG compared to intravesical chemotherapy, reluctance still exists about BCG use.","label":0,"label_text":"Not-Related"}
+{"text":"Key Words: renal failure, proteinuria, angiotensin-converting enzyme inhibitor, ACEI, angiotensin II receptor blocker, ARB.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Coagulase-negative staphylococci were identified and isolated from the vitreous specimen of both patients.","label":0,"label_text":"Not-Related"}
+{"text":"Resolution occurred mostly within 24 to 48 hours after injection.","label":0,"label_text":"Not-Related"}
+{"text":"The intent of the discussion is to alert physicians that the appearance of epiglottis can occur from causes other than infection and that a surgical airway should not be the first thought when such a case arises.","label":0,"label_text":"Not-Related"}
+{"text":"Required doses of Danaparoid were consistently twofold that previously reported for adults.","label":0,"label_text":"Not-Related"}
+{"text":"One large and obstructive thrombus with a long and mobile component, and other smaller and mobile thrombi were detected.","label":0,"label_text":"Not-Related"}
+{"text":"We describe 4 patients with Graves disease who had abnormal increases of serum creatine kinase (CK) concentrations during treatment with antithyroid medications.","label":0,"label_text":"Not-Related"}
+{"text":"By the third day, the patient was having one bowel movement daily.","label":0,"label_text":"Not-Related"}
+{"text":"In early endophthalmitis, Staphylococcus epidermidis was isolated on vitreous culture in 4 (67%) of 6 cases, whereas in late endophthalmitis, this organism was isolated in only 1 (4%) of 27 cases.","label":0,"label_text":"Not-Related"}
+{"text":"The dog made a gradual recovery, with complete return of locomotor function and muscle mass within 2 months.","label":0,"label_text":"Not-Related"}
+{"text":"The major affected sites had been treated 10 years before with Artecoll, a permanent filler containing polymethylmethacrylate.","label":0,"label_text":"Not-Related"}
+{"text":"Marked improvement was noted after the discontinuation of minocycline and the use of systemic corticosteroids.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of posttransplant pulmonary capillaritis in an 8-month-old infant, and demonstrate evidence of C4d deposition and B-lymphocytes in the allograft, donor anti-HLA antibodies in the serum and a clinical and immunohistochemical response to anti-CD20 monoclonal antibody (rituximab) therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Delayed severe multivessel spasm and aborted sudden death after Taxus stent implantation.","label":0,"label_text":"Not-Related"}
+{"text":"Corticosteroids are widely known to have a variety of adverse mental effects.","label":0,"label_text":"Not-Related"}
+{"text":"She also volunteered she had never had a menstrual period and physical examination identified several features of Turner's syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVES: Multidrug resistant tuberculosis (MDR-TB) is an increasing problem in many parts of the world and in Norway the increase has been substantial since 1998.","label":0,"label_text":"Not-Related"}
+{"text":"Linezolid-induced dyserythropoiesis: chloramphenicol toxicity revisited.","label":1,"label_text":"Related"}
+{"text":"We report the first case of a human immunodeficiency virus type 1 (HIV-1)-infected individual receiving combination antiretroviral therapy, which included ritonavir, who developed Cushing syndrome with profound complications after epidural triamcinolone injections.","label":1,"label_text":"Related"}
+{"text":"INTERVENTION: Cessation of treatment with 5-ASA compounds.","label":0,"label_text":"Not-Related"}
+{"text":"Both patients experienced the onset of psychiatric symptoms as young adults, showed a prompt response to antipsychotic drug therapy, and were subsequently left on maintenance treatment for indefinite periods.","label":0,"label_text":"Not-Related"}
+{"text":"Cutaneous reactions to propylthiouracil and methimazole occur in 3%-5% of adults.","label":1,"label_text":"Related"}
+{"text":"DISCUSSION: CIPS is hypothesized to result from calcineurin-induced vascular changes that disturb bone perfusion and permeability, leading to intraosseous vasoconstriction and bone marrow edema.","label":0,"label_text":"Not-Related"}
+{"text":"Many of the therapeutic agents that are used in the ICU may precipitate delirium.","label":0,"label_text":"Not-Related"}
+{"text":"Anticonvulsant hypersensitivity syndrome: is there a role for immunomodulation?","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: The risk of drug-induced rhabdomyolysis due to the potential interaction between lovastatin and azithromycin or clarithromycin should be considered before the concomitant use of these agents.","label":1,"label_text":"Related"}
+{"text":"SUMMARY: Patients with NSTE ACS for whom a conservative treatment strategy is selected should receive enoxaparin, fondaparinux, or unfractionated heparin (UFH) as anticoagulant therapy.","label":0,"label_text":"Not-Related"}
+{"text":"She was transferred to an inpatient psychiatric hospital, where she was taken off risperidone.","label":0,"label_text":"Not-Related"}
+{"text":"To our knowledge, no prior cases of penicillamine-induced TTP in RA have been reported.","label":1,"label_text":"Related"}
+{"text":"A patient with generalized MG was effectively managed with MM but developed CNS lymphoma after 3 years of treatment.","label":1,"label_text":"Related"}
+{"text":"Nevertheless, although rare and usually free of clinically significant sequelae, if contamination is by some virulent organisms such as Staphylococcus aureus, gram-negative bacilli, or fungi, severe complications may occur.","label":0,"label_text":"Not-Related"}
+{"text":"After three weeks of treatment an itching rash appeared.","label":0,"label_text":"Not-Related"}
+{"text":"Most of these patients benefited from therapy and survived longer (median 5 years) than historical control of untreated patients.","label":0,"label_text":"Not-Related"}
+{"text":"A total of 64 patients from 10 series have received the drug from one to 25 months, usually in doses of 50-150 micrograms every eight hours by subcutaneous injection.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was found to have no motile sperm with a normal sperm count, while taking a dose of 400 mg\/day of carbamazepine.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: Rapid infusion of albumin might be a rescue option in cases of severe TRALI with extensive pulmonary capillary leak during the acute phase.","label":0,"label_text":"Not-Related"}
+{"text":"Rhabdomyolysis has been recognized as a complication of tocolytic therapy with ritodrine hydrochloride.","label":1,"label_text":"Related"}
+{"text":"The cough continued for the duration of therapy with quinapril.","label":1,"label_text":"Related"}
+{"text":"All evidence suggests this was an idiosyncratic response to either hepatitis A or yellow fever vaccination.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of long-term systemic administration of prostaglandin E2 (PGE2) to a newborn infant with ductus-dependent congenital heart disease.","label":0,"label_text":"Not-Related"}
+{"text":"The time delay by which symptoms of pancreatitis presented following administration of loop diuretics suggests an immunologic pathway.","label":0,"label_text":"Not-Related"}
+{"text":"Unfortunately, while there are numerous observational reports in the literature, there is not a lot of information concerning the safety and efficacy of particular treatments or the nontreatment of bipolar disorder during pregnancy.","label":0,"label_text":"Not-Related"}
+{"text":"To best of our knowledge, this entity has never been reported as a problem.","label":0,"label_text":"Not-Related"}
+{"text":"We should always consider it as a possible late complication and treat it appropriately.","label":0,"label_text":"Not-Related"}
+{"text":"Reversible coma in children after improper baclofen pump insertion.","label":0,"label_text":"Not-Related"}
+{"text":"Furthermore, pleiotropic effects of ACE inhibitors are unlikely to provide significant benefits in the absence of blood pressure reduction.","label":0,"label_text":"Not-Related"}
+{"text":"Over the ensuing 3 years, recurrent bouts of optic neuritis OU, with dyschromatopsia, and acuity and field loss (arcuate, central, and paracentral scotomas) were controlled with increasing doses of corticosteroids.","label":0,"label_text":"Not-Related"}
+{"text":"Acute delirium resulting from levofloxacin therapy is an exceedingly rare complication that has been thought to occur more commonly in elderly patients.","label":1,"label_text":"Related"}
+{"text":"MATERIALS AND METHODS: Two dialysis patients with recently rejected renal allografts who were hospitalized because of fever of unknown origin are reported.","label":0,"label_text":"Not-Related"}
+{"text":"Topical steroids remain the mainstay of therapy, but topical tacrolimus has recently been used to treat OLP resistant to topical corticosteroids.","label":0,"label_text":"Not-Related"}
+{"text":"We report here on a heretofore undescribed respiratory syncytial virus (RSV) infection in a patient with a long-standing history of refractory CLL that was treated with fludarabine phosphate.","label":1,"label_text":"Related"}
+{"text":"It is concluded that at least some sensory symptoms originate within the nervous system as a manifestation of the disease process and are not secondary effects of the motor disorder.","label":0,"label_text":"Not-Related"}
+{"text":"Our cases constitute the most severe cases of benzarone hepatotoxicity reported so far, and comprise the first cases of (sub)fulminant hepatitis and cirrhosis related to benzarone.","label":1,"label_text":"Related"}
+{"text":"He did not suffer from any allergy but drinking red wine caused vasomotor rhinitis.","label":0,"label_text":"Not-Related"}
+{"text":"A renal route of potassium loss was suspected, but could not be confirmed as potassium excretion did not increase although sodium excretion was augmented [basal sodium output: 56.7 mmol\/24 h; phosphate treatment: 153 mmol\/24 h (p < 0.05)].","label":0,"label_text":"Not-Related"}
+{"text":"Three cases of acute renal toxicity in patients receiving long-term therapy with mitomycin C and 5-fluorouracil are reported.","label":1,"label_text":"Related"}
+{"text":"Looking at calcimimetics impact on hypercalcemia of immobilization: hypotheses and a case study.","label":0,"label_text":"Not-Related"}
+{"text":"Therapeutic strategy of nephrotic syndrome in patients over eighty.","label":0,"label_text":"Not-Related"}
+{"text":"Two children with rheumatic fever developed anicteric hepatitis while on high-dose aspirin therapy.","label":1,"label_text":"Related"}
+{"text":"A 65-year-old female patient presented with jaundice followed 2 days later by severe dyspnea and tachypnea which worsened when patient was lying flat, 1 week after the fourth dose of adalimumab.","label":1,"label_text":"Related"}
+{"text":"We undertook a retrospective analysis of prevalence of QTC prolongation among all patients with computerized ECGs over a 6-month period at one institution and compared it to the prevalence in hospitalized patients with HIV disease.","label":0,"label_text":"Not-Related"}
+{"text":"A 27-year-old man who had a history of bronchial asthma, eosinophilic enteritis, and eosinophilic pneumonia presented with fever, skin eruptions, cervical lymphadenopathy, hepatosplenomegaly, atypical lymphocytosis, and eosinophilia two weeks after receiving trimethoprim (TMP)-sulfamethoxazole (SMX) treatment.","label":1,"label_text":"Related"}
+{"text":"Toxoplasma gondii infection reactivation predominantly occurs among patients after allogeneic haematopoietic stem cell transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"We suggest that oversecretions of GH and IGF-I were strong promoting factors for liver tumorigenesis in this patient.","label":0,"label_text":"Not-Related"}
+{"text":"Gabapentin withdrawal presenting as status epilepticus.","label":1,"label_text":"Related"}
+{"text":"A 61 year-old patient with a history of anxiety disorder presented with stridor after an uneventful laparotomy with a general anesthetic.","label":0,"label_text":"Not-Related"}
+{"text":"Leukaemia cutis in a patient treated for breast cancer.","label":0,"label_text":"Not-Related"}
+{"text":"Prominent eye movements during NREM sleep and REM sleep behavior disorder associated with fluoxetine treatment of depression and obsessive-compulsive disorder.","label":1,"label_text":"Related"}
+{"text":"Further research is needed to delineate the frequency of this troubling side effect and how best to treat it.","label":0,"label_text":"Not-Related"}
+{"text":"Awareness of this may obviate the need for extensive medical evaluations.","label":0,"label_text":"Not-Related"}
+{"text":"Our patient died two and a half months after the diagnosis was made due to sepsis caused by Staphylococcus aureus isolated in hemoculture.","label":0,"label_text":"Not-Related"}
+{"text":"We report four cases of encephalopathy coincident with elevated aluminum levels as well as one patient who developed seizures while receiving continuous bladder irrigations with alum.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND: It has been proposed that the innate immune system plays a central role in driving the autoimmune T-cell cascade leading to psoriasis; however, there is no direct evidence for this.","label":0,"label_text":"Not-Related"}
+{"text":"The authors describe a case of combined lithium and haloperidol toxicity characterized by hyperpyrexia, severe rigidity, mutism, and development of irreversible tardive dyskinesia.","label":1,"label_text":"Related"}
+{"text":"Chemotherapy in massively obese patients may be complicated by difficulty in calculating body surface area.","label":0,"label_text":"Not-Related"}
+{"text":"A 36-year-old man being treated with cisplatinum, vinblastine, and bleomycin for testicular carcinoma developed a dense left homonymous hemianopsia, encephalopathy, and a partial nondominant parietal lobe syndrome.","label":1,"label_text":"Related"}
+{"text":"Life-threatening acute hyponatraemia induced by low dose cyclophosphamide and indomethacin.","label":1,"label_text":"Related"}
+{"text":"Eleven of those patients also experienced clinically compromising anemia, transfusion with packed red blood cells, renal insufficiency, dialysis, or death.","label":0,"label_text":"Not-Related"}
+{"text":"The development of a rifampin-impregnated silicone catheter yielded excellent results in infection prevention and treatment in vitro as well as in an animal model.","label":0,"label_text":"Not-Related"}
+{"text":"The impressive and significant success rate for complete resolution of verrucous lesions without subsequent scarring has shown this approach to be an effective treatment for plantar warts.","label":0,"label_text":"Not-Related"}
+{"text":"Brief report: clonazepam behavioral side effects with an individual with mental retardation.","label":0,"label_text":"Not-Related"}
+{"text":"Despite appropriate anticoagulation therapy with warfarin, echocardiography and fluoroscopy showed stuck leaflets of the prosthetic valve due to thrombosis.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was reintubated and five hours later was successfully extubated without further sequelae.","label":0,"label_text":"Not-Related"}
+{"text":"The article concludes with practical recommendations for clinical practice until futher evidence regarding this association is available.","label":0,"label_text":"Not-Related"}
+{"text":"The possible underlying electrophysiological mechanisms of this phenomenon are discussed in this paper.","label":0,"label_text":"Not-Related"}
+{"text":"In this report, we present a rare case of gastro-duodenal ulcer following selective internal radiation therapy (SIRT).","label":0,"label_text":"Not-Related"}
+{"text":"Streptococcus agalactiae sepsis after transfusion of a plateletpheresis concentrate: benefit of donor evaluation.","label":0,"label_text":"Not-Related"}
+{"text":"SETTING: France.","label":0,"label_text":"Not-Related"}
+{"text":"In many patients, pericardial inflammation continues and pericardial fibrosis and calcification develop, leading to a chronic and rigid constrictive pericarditis.","label":0,"label_text":"Not-Related"}
+{"text":"The benign, self-limited nature of the color change mandates that prostaglandin E1 not be discontinued for this reason.","label":0,"label_text":"Not-Related"}
+{"text":"Avascular necrosis (osteonecrosis) occurs in Crohn's disease, but the rate of this particular complication is not known.","label":0,"label_text":"Not-Related"}
+{"text":"Psoriasis-like skin reaction in a patient with rheumatoid arthritis after sulphasalazine therapy.","label":1,"label_text":"Related"}
+{"text":"Despite infusion of hypertonic saline, his serum Na was not restored to normal.","label":0,"label_text":"Not-Related"}
+{"text":"Strongyloides hyperinfection in a patient with sarcoidosis.","label":0,"label_text":"Not-Related"}
+{"text":"Invasive aspergillosis of the spine is a rare and typically occurred in terminal patients.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was reluctant to resume chemotherapy for his Hodgkin's disease because of his previous presumed skin infections.","label":0,"label_text":"Not-Related"}
+{"text":"To our knowledge, four cases of interstitial pneumonitis associated with fludarabine have been reported in medical literature.","label":1,"label_text":"Related"}
+{"text":"However, 3 months later he developed increased intraocular pressure and a recurrence of the cystoid macular edema.","label":0,"label_text":"Not-Related"}
+{"text":"Because a catheter-related infection was suspected, the Port-A-Cath was removed after a 10-day course of piperacillin-tazobactam.","label":0,"label_text":"Not-Related"}
+{"text":"Clinicians should be aware of the possibility that vinorelbine may cause SIADH and possibly hypokalemia.","label":1,"label_text":"Related"}
+{"text":"The authors describe a case of neuroleptic malignant syndrome that occurred in a patient on amitriptyline and lithium carbonate.","label":1,"label_text":"Related"}
+{"text":"The arterial ketone body ratio (AKBR), which is the ratio of acetoacetate to beta-hydroxybutyrate in arterial blood and which reflects the redox state in liver mitochondria, improved dramatically following treatment.","label":0,"label_text":"Not-Related"}
+{"text":"This simple method was more efficient than intravenous therapy in ameliorating the hypophosphatemia secondary to aggressive hemodiafiltration treatment.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was hospitalized and chelated with EDTA four times over the next 5 years; each time he felt better at the end of his treatment, but he returned to largely the same working conditions.","label":0,"label_text":"Not-Related"}
+{"text":"The final visual acuity was no light perception in the left eye and 3\/6 in the right eye.","label":0,"label_text":"Not-Related"}
+{"text":"All eyes had subfoveal CNV secondary to AMD.","label":0,"label_text":"Not-Related"}
+{"text":"This drug has not been studied prospectively in large numbers of pregnant women and lacks the Food and Drug Administration's approval for gestational use unless benefits clearly outweigh potential fetal harm.","label":0,"label_text":"Not-Related"}
+{"text":"The dog was treated with a combination of systemic antifungals and weaning off immunosuppressants and made a complete recovery.","label":0,"label_text":"Not-Related"}
+{"text":"The patient expired from cachexia three months later.","label":0,"label_text":"Not-Related"}
+{"text":"The mechanical infusion is the easiest method to standardize and monitor.","label":0,"label_text":"Not-Related"}
+{"text":"Infection by human immunodeficiency virus (HIV) may affect joints in different ways.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of RTA secondary to FK506 administration in liver transplantation.","label":1,"label_text":"Related"}
+{"text":"Had a biopsy and cultures not been done, the diagnosis of aspergillosis would have been missed and the patient might have been treated with chemotherapy, with a potentially lethal outcome.","label":0,"label_text":"Not-Related"}
+{"text":"In nine cases of botulism B infection due to food poisoning acute onset of accommodation paresis, mydriasis, and dry-eye symptoms were the prominent clinical findings.","label":0,"label_text":"Not-Related"}
+{"text":"Extensive microbiological investigation remained negative and video-assisted thoracoscopic lung biopsy demonstrated diffuse alveolar damage.","label":0,"label_text":"Not-Related"}
+{"text":"Premortem serum and postmortem tissue aluminum levels were markedly elevated.","label":0,"label_text":"Not-Related"}
+{"text":"Candida chorioamnionitis after serial therapeutic amniocenteses: a possible association.","label":0,"label_text":"Not-Related"}
+{"text":"Nocardiosis after corticosteroid therapy for malignant thymoma.","label":0,"label_text":"Not-Related"}
+{"text":"Phenylpropanolamine-induced psychosis.","label":1,"label_text":"Related"}
+{"text":"Angioedema and maculopapular eruptions associated with carbamazepine administration.","label":1,"label_text":"Related"}
+{"text":"Transient bullous dermolysis of the newborn does not represent an obstacle to administering appropriate chemotherapy when simple precautions are taken.","label":0,"label_text":"Not-Related"}
+{"text":"The clinical features of these nine patients combined with 15 previously reported cases were analyzed to determine factors associated with hemorrhagic worsening.","label":0,"label_text":"Not-Related"}
+{"text":"Children with acute lymphoblastic leukemia (ALL), treated with L-asparaginase are at risk for cerebral thrombosis or hemorrhage because of coagulation protein deficiencies.","label":1,"label_text":"Related"}
+{"text":"RESULTS: The in vitro hemodialysis model showed that ifosfamide was cleared with an extraction ratio of 86.7+\/-0.5% and remained constant even at low concentrations of drug.","label":0,"label_text":"Not-Related"}
+{"text":"As combination of chemotherapy and Gemtuzumab may become a common induction regimen for CD33+ AML patients, there is no report assessing the safety and toxicity of a re-treatment at relapse with such combination in a same patient.","label":0,"label_text":"Not-Related"}
+{"text":"Cystoid macular edema in a low-risk patient after switching from latanoprost to bimatoprost.","label":1,"label_text":"Related"}
+{"text":"We postulate that cyclosporin, possibly together with ganciclovir, can produce transient brain stem or neuromuscular dysfunction with eye movement abnormality in occasional patients.","label":1,"label_text":"Related"}
+{"text":"At the time of her first consultation at our clinic, the ultrasound examination showed a complete involution of her venous thrombosis.","label":0,"label_text":"Not-Related"}
+{"text":"The renin-angiotensin-aldosterone system appears to play an important initiating role in the pathogenesis of hypertension in patients with autosomal-dominant polycystic kidney disease (ADPKD).","label":0,"label_text":"Not-Related"}
+{"text":"If used at high dosage, it may cause a secondary form of adult hemolytic-uremic syndrome (HUS).","label":0,"label_text":"Not-Related"}
+{"text":"She has persistent proteinuria and is currently undergoing a trial of high-dose steroid therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Pilocarpine toxicity and the treatment of xerostomia.","label":1,"label_text":"Related"}
+{"text":"Domestic dogs and cats may be another reservoir.","label":0,"label_text":"Not-Related"}
+{"text":"These concerns may be reinforced by advice in the UK product information sheet to perform LFTs before and during treatment, by high infection rates with hepatitis C virus (HCV) among injecting heroin addicts and by the frequency of abnormal LFTs in alcohol abusers.","label":0,"label_text":"Not-Related"}
+{"text":"A trial of thrombolytic therapy with tissue plasminogen activator infusions was started at 0.1 mg\/kg\/hr for 6 hrs daily.","label":0,"label_text":"Not-Related"}
+{"text":"Hiccupping is a characteristic noise caused by a sudden closure of the glottis after repeated, involuntary, spasmodic contraction of the respiratory muscles.","label":0,"label_text":"Not-Related"}
+{"text":"One child showed massive cell destruction which caused hyperuricemic nephropathy.","label":0,"label_text":"Not-Related"}
+{"text":"Candida albicans shunt infection.","label":0,"label_text":"Not-Related"}
+{"text":"Here we report four cases.","label":0,"label_text":"Not-Related"}
+{"text":"We reviewed the slides of 28 brain biopsies diagnostic of PML.","label":0,"label_text":"Not-Related"}
+{"text":"Overdose of magnesium sulfate in combination with renal insufficiency, hypocalcemia, or compromise of intestinal integrity may predispose horses to magnesium toxicosis.","label":1,"label_text":"Related"}
+{"text":"Drug-induced fever due to diltiazem.","label":1,"label_text":"Related"}
+{"text":"RESULTS: A patient developed a bilaterally symmetric bull's-eye maculopathy 45 years after taking quinacrine for 18 months as prophylaxis against malaria.","label":1,"label_text":"Related"}
+{"text":"We discuss this case and issues arising from it related to the use of CD34+ selected stem cells for transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"This regimen led to a significant and long-lasting reduction of proteinuria.","label":0,"label_text":"Not-Related"}
+{"text":"A reduction of up to 33 percent in pituitary tumor size has been reported in more than half of the 27 cases studied from four groups.","label":0,"label_text":"Not-Related"}
+{"text":"His diarrhea, consisting of 10 to 12 loose stools a day, had continued for approximately two weeks and was accompanied with abdominal cramping, fever, anorexia, and weight loss.","label":0,"label_text":"Not-Related"}
+{"text":"The image illustrates the rash seen with this drug reaction.","label":0,"label_text":"Not-Related"}
+{"text":"Valproic acid induced coma is presented in an adult patient without a history of metabolic disease.","label":1,"label_text":"Related"}
+{"text":"The neurological manifestations developed within one week after the last dose of Ara-C and persisted for over 8 weeks.","label":0,"label_text":"Not-Related"}
+{"text":"The day after clozapine was stopped, while he was still receiving clomipramine 150 mg\/d, he began behaving oddly, started sweating profusely, shivering, and became tremulous, agitated, and confused.","label":1,"label_text":"Related"}
+{"text":"Therapy-related leukemia and myelodysplastic syndrome in chronic lymphocytic leukemia.","label":0,"label_text":"Not-Related"}
+{"text":"L-asparaginase-induced severe necrotizing pancreatitis successfully treated with percutaneous drainage.","label":1,"label_text":"Related"}
+{"text":"A 46-year-old woman was brought to the Emergency Department after being found confused and nonverbal while wandering in a field.","label":0,"label_text":"Not-Related"}
+{"text":"After 4 years in complete remission, he developed a CD20-negative T-cell-rich B-cell lymphoma (TCRBCL) presenting as multiple lung lesions.","label":0,"label_text":"Not-Related"}
+{"text":"PURPOSE: A case of carbamazepine-induced hyperammonemia is presented.","label":1,"label_text":"Related"}
+{"text":"Four of the eight patients had no detectable plasma cryofibrinogen after treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Two weeks following rechallenge with alendronate sodium resulted in recurrence of his scleritis.","label":1,"label_text":"Related"}
+{"text":"Phenothiazine treatment and respiratory distress syndrome in a child.","label":0,"label_text":"Not-Related"}
+{"text":"In the other patient, a 78-year-old woman, Neisseria mucosa knee arthritis occurred after a single sodium hyaluronate injection.","label":1,"label_text":"Related"}
+{"text":"Drug provocation test is a controlled drug treatment which aims at making diagnosis of hypersensitivity reaction to drugs.","label":0,"label_text":"Not-Related"}
+{"text":"Acute vision loss after intravitreal injection of bevacizumab (avastin) associated with ocular ischemic syndrome.","label":1,"label_text":"Related"}
+{"text":"Discontinuation of the drug resulted in total resolution of the clinical and radiologic abnormalities.","label":0,"label_text":"Not-Related"}
+{"text":"A 55-year-old woman presented an episode of acute urticaria and labial angioedema 60 minutes after ingesting 500 mg of cloxacillin for a skin abscess.","label":1,"label_text":"Related"}
+{"text":"The pathogenesis of augmentation is unclear.","label":0,"label_text":"Not-Related"}
+{"text":"There were no perioperative or long-term complications of the single-pass technique.","label":0,"label_text":"Not-Related"}
+{"text":"Pancreatitis is a very rare adverse effect associated with the use of amiodarone, and only four cases of amiodarone-induced pancreatitis have been reported in literature.","label":1,"label_text":"Related"}
+{"text":"Eleven days after initiation of therapy with amiodarone, the patient experienced syncope and was noted to have recurrent episodes of polymorphous ventricular tachycardia.","label":1,"label_text":"Related"}
+{"text":"Cholestatic hepatitis after administration of furan derivatives.","label":0,"label_text":"Not-Related"}
+{"text":"Physical examination revealed a healthy appearance of the palms; however, 5 min after immersion of the hands in warm water, the central part of the left palm became swollen and tiny white papules with dilated puncta appeared.","label":0,"label_text":"Not-Related"}
+{"text":"Endometrial squamous metaplasia.","label":0,"label_text":"Not-Related"}
+{"text":"We review the medical literature about mucormycosis peritonitis which, albeit rare, carries very high mortality.","label":0,"label_text":"Not-Related"}
+{"text":"Corticosteroid therapy was continued, but azathioprine was stopped after diagnosis.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment is mainly discontinuation of the drug, however, corticosteroid therapy is recommended for severe reactions.","label":0,"label_text":"Not-Related"}
+{"text":"Four weeks earlier she had developed hepatopathy during a regimen of carbamazepine, lynestrenol and sodium valproate.","label":1,"label_text":"Related"}
+{"text":"Clinical resolution was achieved with granulocyte colony-stimulating factor and amphotericin B administration.","label":0,"label_text":"Not-Related"}
+{"text":"Agitation includes combativeness, hyperactivity, disinhibition, wandering, and restlessness.","label":0,"label_text":"Not-Related"}
+{"text":"In that case, as well as the one reported here, hepatitis symptoms occurred after completion of long-term treatment in patients who were asymptomatic both before and during therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Probable enoxaparin-induced hepatotoxicity.","label":1,"label_text":"Related"}
+{"text":"From these data, acute generalized dystonia with brainstem and thalamic lesions may occur in WD patients after an initial d-penicillamine therapy.","label":1,"label_text":"Related"}
+{"text":"She initially presented with pelvic and lower back pain, and imaging showed a pelvic deep venous thrombosis (DVT) and an interrupted IVC.","label":0,"label_text":"Not-Related"}
+{"text":"There was a dramatic increase in cardiac output 20 minutes after LS infusion, and weaning from cardiopulmonary bypass circulation was achieved.","label":0,"label_text":"Not-Related"}
+{"text":"The process is classified as a nonvasculitic pustular bacterid, and as a prototype for antigen localization of lesions to the occluded epidermal sweat duct unit.","label":0,"label_text":"Not-Related"}
+{"text":"Based upon the observed fall of the filtration fraction, the rise in the relative clearance of 99Tc-dimercaptosuccinic acid and the increase in proteinuria, we suggest that in this case the tubules and\/or interstitium are the main targets for cyclosporine A nephrotoxicity.","label":1,"label_text":"Related"}
+{"text":"The discontinuation of HAART led to the complete resolution of signs and symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"Both PAN and methotrexate have been independently demonstrated to cause sensorineural hearing loss.","label":1,"label_text":"Related"}
+{"text":"Torsades de pointes were preceded and associated with marked QT prolongation and bradycardia.","label":0,"label_text":"Not-Related"}
+{"text":"CASE SUMMARY: A 65-year-old patient chronically treated with the selective serotonin reuptake inhibitor (SSRI) citalopram developed confusion, agitation, tachycardia, tremors, myoclonic jerks and unsteady gait, consistent with serotonin syndrome, following initiation of fentanyl, and all symptoms and signs resolved following discontinuation of fentanyl.","label":1,"label_text":"Related"}
+{"text":"METHODS: A 68-year-old man developed intense conjunctival hyperemia and cystoid macula edema after switching from latanoprost to bimatoprost 9 months after cataract surgery in an eye at low-risk for this cystoid macular edema.","label":1,"label_text":"Related"}
+{"text":"Acanthamoeba keratitis.","label":0,"label_text":"Not-Related"}
+{"text":"For this goal, a moist environment may be the optimal choice for topical therapy.","label":0,"label_text":"Not-Related"}
+{"text":"The cutaneous lesion consisted of an erythematous and scaly plaque on the leg measuring 2 x 2 cm.","label":0,"label_text":"Not-Related"}
+{"text":"The possibility that a higher incidence of adverse events occurs in a vulnerable population has not been systematically addressed, and seems called for.","label":0,"label_text":"Not-Related"}
+{"text":"Our experience with the two cases reported here has led us to propose guidelines for the treatment of initial PTE in a pediatric hematology unit.","label":0,"label_text":"Not-Related"}
+{"text":"QTc interval was measured before and after intervention.","label":0,"label_text":"Not-Related"}
+{"text":"A causal relationship of phrenal neuropathy with adalimumab is herein discussed.","label":0,"label_text":"Not-Related"}
+{"text":"Overnight sleep studies and multiple sleep latency testing were carried out under double-blind administration of either L-dopa or placebo.","label":0,"label_text":"Not-Related"}
+{"text":"The case history of a 42 year old male on CAPD who was receiving sodium nitroprusside (SNP) for hypertensive encephalopathy is described.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of an 87-year-old white woman with myasthenia gravis who presented with nausea, shortness of breath, azotemia, and hyperkalemia shortly after completing a course of intravenous immunoglobulin (IVIG).","label":1,"label_text":"Related"}
+{"text":"According to the Naranjo probability scale, the relationship of gemcitabine treatment with cutaneous eruption in our patient is possible.","label":1,"label_text":"Related"}
+{"text":"CASE SUMMARY: A 71-year-old woman visited a psychiatrist in September 2007 for her depressed mood.","label":0,"label_text":"Not-Related"}
+{"text":"DPD deficiency follows an autosomal recessive pattern of inheritance, and its prevalence is estimated to be 3%.","label":0,"label_text":"Not-Related"}
+{"text":"Besides, failure to thrive, increased bone fragility resulting in frequent fractures and recurrent bone infections are the other characteristic features.","label":0,"label_text":"Not-Related"}
+{"text":"This severe illness was likely caused by minocycline, and we speculate that minocycline may have acted as a superantigen, causing lymphocyte over-activation and massive cytokine release.","label":1,"label_text":"Related"}
+{"text":"Neurologic degeneration associated with nitrous oxide anesthesia in patients with vitamin B12 deficiency.","label":1,"label_text":"Related"}
+{"text":"RESULTS: The patient had fungal endophthalmitis, with O. sulphureo-ochraceum present in the lens capsule.","label":0,"label_text":"Not-Related"}
+{"text":"Acanthamoeba keratitis related to cosmetic contact lenses.","label":0,"label_text":"Not-Related"}
+{"text":"We discuss the possible role of using immunomodulating agents for the treatment of this syndrome and suggest that alternative regimens should be given special consideration especially in those critical clinical situations where supportive measures appear to be unsuccessful.","label":0,"label_text":"Not-Related"}
+{"text":"This unique syndrome should be identified as a direct causal effect of paclitaxel.","label":0,"label_text":"Not-Related"}
+{"text":"Drug eruption caused by azathioprine: value of using the drug-induced lymphocytes stimulation test for diagnosis.","label":1,"label_text":"Related"}
+{"text":"Seizure with single-pulse transcranial magnetic stimulation in a 35-year-old otherwise-healthy patient with bipolar disorder.","label":0,"label_text":"Not-Related"}
+{"text":"We describe the case of a 20-year-old Caucasian male affected by enteropathic (Crohn's disease) spondyloarthropathy HLA B27 negative, successfully treated with infliximab.","label":0,"label_text":"Not-Related"}
+{"text":"Propranolol: an unrecognized cause of central nervous system dysfunction in patients undergoing cardiopulmonary bypass.","label":1,"label_text":"Related"}
+{"text":"The clinical aspect closely resembled classical transient global amnesia but the episode after clioquinol lasted longer (24 hours to three days) and a more or less extensive retrograde amnesia persisted permanently.","label":1,"label_text":"Related"}
+{"text":"This is the second report of acute lung injury and diffuse alveolar damage caused by mefloquine.","label":1,"label_text":"Related"}
+{"text":"RESULTS: Of a total of 231 patients, 13 (5.6%) developed an infection of the central venous line, with fever that was very high in some cases.","label":0,"label_text":"Not-Related"}
+{"text":"Adverse reaction in a patient with aspirin-induced asthma treated with zafirlukast.","label":1,"label_text":"Related"}
+{"text":"Mycophenolate mofetil used previously in transplantation, has recently been shown to be useful in autoimmune blistering disorders.","label":0,"label_text":"Not-Related"}
+{"text":"One should therefore be aware of possible extrapyramidal side effects with olanzapine that are reduced compared to classical neuroleptic drugs but not completely eliminated.","label":1,"label_text":"Related"}
+{"text":"At this time, the TSH response to TRH was normal and the patient was considered fully recovered.","label":0,"label_text":"Not-Related"}
+{"text":"Cis-retinoic acid (RA) may further increase the risk of developing BMTN.","label":1,"label_text":"Related"}
+{"text":"Temporary amelioration was achieved following plasmapheresis; however, this and other measures were unsuccessful in controlling the thyrotoxicosis, which deteriorated to thyroid storm.","label":0,"label_text":"Not-Related"}
+{"text":"A second renal biopsy showed improvement of acute tubular necrosis and endocapillary proliferation and transformation of crescents into a fibrous form.","label":0,"label_text":"Not-Related"}
+{"text":"The refractive state of lesion eye was -5.5D\/-1.25D x 180 degrees, and visual acuity was hand motion at 30 cm.","label":0,"label_text":"Not-Related"}
+{"text":"Generalized lichen nitidus with involvement of the palms following interferon alpha treatment.","label":1,"label_text":"Related"}
+{"text":"He had an immediate hypersensitivity reaction during the initiation of the MTX infusion with diffuse urticaria, facial swelling, cough, and chest tightness.","label":1,"label_text":"Related"}
+{"text":"Dilated cardiomyopathy associated with chronic overuse of an adrenaline inhaler.","label":1,"label_text":"Related"}
+{"text":"Massive CBZ OD may produce a reversible encephalopathy that includes cortical hyperexcitability, a profound burst-suppression EEG pattern, and cranial nerve areflexia.","label":1,"label_text":"Related"}
+{"text":"Post-allogeneic haematopoietic stem cell transplantation membranous nephropathy: clinical presentation, outcome and pathogenic aspects.","label":0,"label_text":"Not-Related"}
+{"text":"Myelodysplastic syndrome in a patient with adult T-cell leukaemia.","label":0,"label_text":"Not-Related"}
+{"text":"Recent studies have reported that patients with GD are at an increased risk of developing malignancies.","label":0,"label_text":"Not-Related"}
+{"text":"Autoimmune hepatitis associated with the use of black cohosh: a case study.","label":0,"label_text":"Not-Related"}
+{"text":"A disulfiram-like reaction was noticed each time.","label":0,"label_text":"Not-Related"}
+{"text":"Eight patients over 21 months underwent a combined intravenous-intra-arterial approach.","label":0,"label_text":"Not-Related"}
+{"text":"Two months later, he was referred to Dhahran Health Center, and admitted with fever, abdominal pain, dysuria, and severe fatigue.","label":0,"label_text":"Not-Related"}
+{"text":"PURPOSE: We evaluated the in vitro hemodialysis ratio and subsequent toxicity and pharmacokinetics of ifosfamide in an anephric patient with Wilms' tumor.","label":1,"label_text":"Related"}
+{"text":"Standard therapy directed at volume overload quickly cleared the pulmonary congestion, and the pregnancy progressed uneventfully to term.","label":0,"label_text":"Not-Related"}
+{"text":"A 63-year-old man with diabetes mellitus for 15 years was admitted to our hospital in 1990 because of end-stage renal failure.","label":0,"label_text":"Not-Related"}
+{"text":"A child in whom a phenobarbital hypersensitivity drug reaction developed which consisted of fever, a pruritic desquamating erythrodermic rash, alopecia, icterus, protein-losing enteropathy, myositis, and nephritis, is described.","label":1,"label_text":"Related"}
+{"text":"The psoralen derivatives used in the study were 8-methoxypsoralen (8MOP), 3-carbethoxypsoralen (3CPs), 4,6,4'-trimethylangelicin (TMA) and 7-methyl pyridopsoralen (MPP).","label":0,"label_text":"Not-Related"}
+{"text":"Hepatotoxicity from green tea: a review of the literature and two unpublished cases.","label":0,"label_text":"Not-Related"}
+{"text":"The observation of responses in 3 patients with T315I phenotype-refractory CML or Ph-positive ALL, at doses of MK-0457 associated with no significant extramedullary toxicity, is very encouraging.","label":0,"label_text":"Not-Related"}
+{"text":"We describe three patients with long-standing seropositive rheumatoid arthritis (RA) on chronic corticosteroid therapy who experienced very early (1-6 h) mortality after the use of intravenous thrombolytic therapy for the treatment of AMI.","label":0,"label_text":"Not-Related"}
+{"text":"Milk-alkali syndrome induced by 1,25(OH)2D in a patient with hypoparathyroidism.","label":1,"label_text":"Related"}
+{"text":"During clarithromycin coadministration, four out of the seven patients developed moderate-to-severe toxic symptoms of carbamazepine, such as drowsiness, dizziness, and ataxia, which resolved within 5 days after clarithromycin discontinuation.","label":1,"label_text":"Related"}
+{"text":"The authors report a case of urinary incontinence (UI) that occurred in a woman after administration of venlafaxine.","label":1,"label_text":"Related"}
+{"text":"Multiple mechanisms for ciprofloxacin-induced nephrotoxicity have been proposed.","label":1,"label_text":"Related"}
+{"text":"These agents are increasingly associated with infections, particularly mycobacterial infections.","label":0,"label_text":"Not-Related"}
+{"text":"PURPOSE: To report two cases in which topical brimonidine resulted in apparent central nervous system depression and unresponsiveness in an infant.","label":1,"label_text":"Related"}
+{"text":"Normalization of generalized retinal function and progression of maculopathy after cessation of therapy in a case of severe hydroxychloroquine retinopathy with 19 years follow-up.","label":1,"label_text":"Related"}
+{"text":"Bone marrow aplasia and severe skin rash after a single low dose of methotrexate.","label":1,"label_text":"Related"}
+{"text":"Autopsy revealed that the lung\/bodyweight ratio was 0.0096 (>0.015) and pulmonary hypoplasia was noted.","label":0,"label_text":"Not-Related"}
+{"text":"It can be caused by infection of the donor or by contamination of the organ during harvest, preservation and handling, or at transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"This report details the pulmonary pathologic findings in four patients with rheumatoid arthritis, who developed new onset of pulmonary signs and symptoms with alveolar infiltrates temporally related to the institution of etanercept therapy.","label":1,"label_text":"Related"}
+{"text":"Despite the severity of their illness, all patients but one survived.","label":0,"label_text":"Not-Related"}
+{"text":"The authors report a longitudinal case study of a woman with a history of bipolar affective disorder in which L-dopa shortened the manic-depressive cycle length when administered in a double-blind trial.","label":1,"label_text":"Related"}
+{"text":"The results of an Intergroup trial, coordinated by the Southwest Oncology Group (SWOG) demonstrated markedly superior progression free and overall survival for combined chemoradiotherapy compared to radiotherapy alone.","label":0,"label_text":"Not-Related"}
+{"text":"It is known to cause dyschromatopsia, visual disturbances, and visual-field defects.","label":0,"label_text":"Not-Related"}
+{"text":"Their parents were also found to be G6PD deficient.","label":0,"label_text":"Not-Related"}
+{"text":"This case shows the difficulties in the diagnosis of CD20-negative lymphomas when the number of tumor cells is low and when they are found in a predominant T-cell context.","label":0,"label_text":"Not-Related"}
+{"text":"Although they had complex medical problems, the high serum concentrations of ampicillin at the time of seizures without their recurrence after discontinuing the antibiotic suggest that the seizures were related to the ampicillin therapy.","label":1,"label_text":"Related"}
+{"text":"Multiple complications can occur as a consequence of insertion of a VAD.","label":0,"label_text":"Not-Related"}
+{"text":"The mean decrease in vivo following hemodialysis for ifosfamide, chloroacetaldehyde, and 4-hydroxyifosfamide were 86.9%, 77.2%, and 36.2%, respectively.","label":0,"label_text":"Not-Related"}
+{"text":"Probable interaction between tolterodine and warfarin.","label":0,"label_text":"Not-Related"}
+{"text":"When the patient was subsequently treated by parenteral administration of Org 10172 as anticoagulant over a period of several weeks the number of platelets rapidly increased and the patient almost completely recovered.","label":0,"label_text":"Not-Related"}
+{"text":"The EEG examination, in its third attempt, revealed bilateral multiple symmetric spikes on photic stimulation.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a 57-year-old man with acral erythrocyanosis progressing to acute digital ischemia and gangrene that developed after combined chemotherapy (bleomycin and methotrexate) used to treat a metastatic squamous cell carcinoma of the hypopharynx.","label":1,"label_text":"Related"}
+{"text":"The patient was treated medically with conventional amphotericin during the first episode.","label":0,"label_text":"Not-Related"}
+{"text":"Hypotensive shock and angio-oedema from angiotensin II receptor blocker: a class effect in spite of tripled tryptase values.","label":0,"label_text":"Not-Related"}
+{"text":"Aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension in a patient treated with trimethoprim-sulfamethoxazole.","label":1,"label_text":"Related"}
+{"text":"These reactions recurred immediately after the second dose.","label":0,"label_text":"Not-Related"}
+{"text":"Soon after its introduction in 1952, chlorpromazine was noted to induce symptoms resembling Parkinson's disease.","label":1,"label_text":"Related"}
+{"text":"Clinically, the data are suggestive of the need to assimilate HRT to the natural circadian cortisol rhythm and not restrict it to the active part of the day.","label":0,"label_text":"Not-Related"}
+{"text":"The advantages and disadvantages of uncontrolled case reports are reviewed using two cases of false-positive reactions to drugs as illustrative examples.","label":0,"label_text":"Not-Related"}
+{"text":"The diagnosis was suspected in the setting of a negative anion gap and only later confirmed by direct measurement of the serum bromide level.","label":0,"label_text":"Not-Related"}
+{"text":"No symptomatic hypoglycemia or sudden incapacitation occurred.","label":0,"label_text":"Not-Related"}
+{"text":"Cardiobacterium hominis endocarditis in a patient with a hypersensitivity reaction to penicillin.","label":0,"label_text":"Not-Related"}
+{"text":"Nocardia exalbida was isolated in Japan and characterized within the genus Nocardia.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment was for various tumors at advanced stages, and in some patients, other anticancer drugs previously had been administered.","label":0,"label_text":"Not-Related"}
+{"text":"The relevant literature is reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was treated with ethanol, then fomepizole intravenously (15, 10, then 5 mg\/kg), and hemodialysis.","label":0,"label_text":"Not-Related"}
+{"text":"Imatinib mesylate therapy in patients with gastrointestinal stromal tumors and impaired liver function.","label":0,"label_text":"Not-Related"}
+{"text":"We report here our results concerning this complication which may occur in any patient with Hodgkin's disease undergoing intensive therapy.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To report a case of rhabdomyolysis caused by Commiphora mukul, a natural lipid-lowering agent.","label":0,"label_text":"Not-Related"}
+{"text":"Acute psychotic reaction with visual hallucination, delusion, panic reaction and myoclonic movement of hands developed on day 3 of admission.","label":0,"label_text":"Not-Related"}
+{"text":"Previous associations with a drug or food allergy, allergic rhinitis, atopic dermatitis, and elevated IgE levels suggest an atopic predisposition in the pathogenesis of this disorder.","label":0,"label_text":"Not-Related"}
+{"text":"This case report highlights the powerful anti-natriuretic properties of GH.","label":0,"label_text":"Not-Related"}
+{"text":"INV(12) (p13q11) and dicentric chromosomes in a secondary leukaemia with basophilia.","label":0,"label_text":"Not-Related"}
+{"text":"Strongyloides hyperinfection syndrome has not been reported in lung transplant recipients.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: We retrospectively reviewed all cases of endoscopic sinus surgery performed by the senior authors at their respective institutions.","label":0,"label_text":"Not-Related"}
+{"text":"This therapy was ceased in four patients due to neutropenia (22%).","label":0,"label_text":"Not-Related"}
+{"text":"She has had no further episodes since substitution of aurothioglucose.","label":0,"label_text":"Not-Related"}
+{"text":"Donor hearts were transported from distant hospitals (Tokyo and Miyagi prefecture) and the transportation time was 1 h 33 min and 2h 4 min, respectively.","label":0,"label_text":"Not-Related"}
+{"text":"Histopathology was suggestive of a cutaneous drug eruption.","label":0,"label_text":"Not-Related"}
+{"text":"To our knowledge, no pediatric renal transplant recipient who had thyroid carcinoma or two different types of tumor has been reported in Japan.","label":0,"label_text":"Not-Related"}
+{"text":"The patient developed neurologic signs and symptoms including disorientation, oculomotor defects, ataxia and multifocal myoclonus during both attempts at HAI.","label":0,"label_text":"Not-Related"}
+{"text":"While ethambutol treatment is most commonly instituted for pulmonary tuberculosis, it is interesting to note that both of these patients had renal tuberculosis.","label":0,"label_text":"Not-Related"}
+{"text":"Hydrocortisone may decrease the incidence of mortality associated with cardiac arrhythmias in children receiving amphotericin B overdoses.","label":1,"label_text":"Related"}
+{"text":"We report one case of non-Hodgkin lymphoma in a patient, with a 30-year history of rheumatoid arthritis, taking low dose methotrexate weekly over a 10-month period.","label":1,"label_text":"Related"}
+{"text":"We describe the first case of disseminated salmonellosis in a patient treated with temozolomide.","label":1,"label_text":"Related"}
+{"text":"Pregancy complicated by acute myeloid leukaemia.","label":0,"label_text":"Not-Related"}
+{"text":"Unintended exposure to acyclovir early in pregnancy, which is not uncommon, may cause excessive maternal and physician anxiety.","label":1,"label_text":"Related"}
+{"text":"Acute bilateral phrenic neuropathy following treatment with adalimumab.","label":1,"label_text":"Related"}
+{"text":"However, complications due to renal tubular acidosis (RTA) have recently been reported.","label":0,"label_text":"Not-Related"}
+{"text":"No further deterioration in the systemic disease occurred.","label":0,"label_text":"Not-Related"}
+{"text":"While the introduction of carmustine wafers (Gliadel wafers) into the tumor resection cavity has been shown to be a beneficial therapy for malignant glioma, it is recognized that clinically significant cerebral edema is a potential adverse effect.","label":1,"label_text":"Related"}
+{"text":"The most important solvents in this respect are methanol, toluene, carbon disulfide, and n-hexane.","label":0,"label_text":"Not-Related"}
+{"text":"The eruption was characterized by generalized, pruritic, eczematous dermatitis.","label":0,"label_text":"Not-Related"}
+{"text":"Laboratory investigation showed; anemia (Hb 7.7 g\/dl), slightly elevated liver function tests, elevated total bilirubin, and ESR.","label":0,"label_text":"Not-Related"}
+{"text":"By now, there are no reports in literature of agranulocytosis caused by tumur necrosis factor-alpha blockers.","label":0,"label_text":"Not-Related"}
+{"text":"Radiologic findings were consistent with PI.","label":0,"label_text":"Not-Related"}
+{"text":"A wide variety of adverse central nervous system effects have been reported in association with propafenone; dizziness is the most common.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: The administration of prostaglandin E1 to neonates can cause gastric-outlet obstruction due to antral hyperplasia.","label":1,"label_text":"Related"}
+{"text":"Addition of in vivo alemtuzumab to the conditioning regimen enabled 2- or 3-locus-mismatched hematopoietic stem cell transplantation with an acceptable incidence of graft-versus-host-disease.","label":0,"label_text":"Not-Related"}
+{"text":"Bullous Pemphigoid (BP) is an autoimmune subepidermal blistering disease appearing predominantly in the elderly.","label":0,"label_text":"Not-Related"}
+{"text":"\"Broken heart syndrome\" after separation (from OxyContin).","label":0,"label_text":"Not-Related"}
+{"text":"Thrombolytic treatment may be affected by minor to relevant complications such as peripheral or central embolization but in our experience and according to the literature it seems much less hazardous than re-do surgery.","label":0,"label_text":"Not-Related"}
+{"text":"Amyloid deposits in the thyroid were found on fine-needle aspiration biopsy.","label":0,"label_text":"Not-Related"}
+{"text":"A report of 4 cases.","label":0,"label_text":"Not-Related"}
+{"text":"There have been few reports regarding the clinical association of DIHS with pathogens other than herpes viruses.","label":0,"label_text":"Not-Related"}
+{"text":"This is the first documented report of human infection caused by this micro-organism.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment with infliximab is known to produce an increase of autoantibodies (antinuclear antibodies, anti-double-stranded DNA), but not clinical disease.","label":1,"label_text":"Related"}
+{"text":"A 68-year-old man suddenly developed extensive bleeding due to severe thrombocytopenia.","label":0,"label_text":"Not-Related"}
+{"text":"Azithromycin has been shown to be beneficial in several diseases with chronic neutrophilic inflammation of the airways, such as cystic fibrosis and bronchiolitis obliterans syndrome (BOS) after lung transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To determine the frequency of weight loss in patients treated with leflunomide for rheumatoid arthritis at an arthritis referral center.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND: Cutaneous manifestations of cryofibrinogenemia include purpura, ecchymosis, and ulcerations.","label":0,"label_text":"Not-Related"}
+{"text":"CASE SUMMARY: An AIDS patient experienced an exacerbation of cytomegalovirus retinitis and was treated with foscarnet.","label":0,"label_text":"Not-Related"}
+{"text":"We present a case of CMV pneumonitis in a woman with stage IV breast cancer, with brain metastases, receiving both chemotherapy and systemic corticosteroids.","label":0,"label_text":"Not-Related"}
+{"text":"However, supplementation with corticosteroids can lead to recurrence, and care should be taken when corticosteroids are being considered.","label":0,"label_text":"Not-Related"}
+{"text":"Insulin-induced cardiac failure.","label":1,"label_text":"Related"}
+{"text":"The plasma concentration of pirmenol was at a subtherapeutic level and the lymphocyte stimulation test was positive in this patient.","label":0,"label_text":"Not-Related"}
+{"text":"Follow up, at six months, after stopping the course of treatment, patient was asymptomatic except for slight bilateral non-tender breast enlargement.","label":0,"label_text":"Not-Related"}
+{"text":"It was hypothesized that valproic acid may interfere with glucuronidation of lamotrigine, leading to increased serum lamotrigine levels, or perhaps alter the drug's metabolism, resulting in accumulation of a toxic intermediate metabolite.","label":1,"label_text":"Related"}
+{"text":"When SASP was changed to 5-aminosalicylic acid (5-ASA), his skin eruptions were resolved, however, he developed weakness and atrophy in his right arm as well as progressive worsening of the dysesthesia in his legs and gait disturbance.","label":1,"label_text":"Related"}
+{"text":"RESULTS: In both cases, magnetic resonance imaging demonstrated multiple small high-intensity areas in the cerebral white matter and spinal cord, while cerebrospinal fluid examination disclosed mononuclear cell increase and protein elevation including myelin basic protein, all of which simulated the features of multiple sclerosis.","label":0,"label_text":"Not-Related"}
+{"text":"In this case, immediate discontinuation of the chemotherapeutic agent apparently reversed the patient's symptoms and findings on MRI.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients who initially reacted to an oral solution formulation subsequently tolerated the corn oil-based soft gelatin capsule.","label":0,"label_text":"Not-Related"}
+{"text":"In the second case, five cardiac arrests due to ventricular tachycardia and fibrillation occurred during several hours after beginning a trial of bretylium maintenance therapy for complex ventricular ectopy.","label":1,"label_text":"Related"}
+{"text":"Late free-flap salvage with catheter-directed thrombolysis.","label":0,"label_text":"Not-Related"}
+{"text":"Neurologic examinations were normal in 2 and showed developmental delay of expressive language in the third.","label":0,"label_text":"Not-Related"}
+{"text":"Interferon-induced sarcoidosis is well documented.","label":0,"label_text":"Not-Related"}
+{"text":"The vasopressin was stopped, and the skin lesion progressed to bullae formation with extensive superficial erosion.","label":0,"label_text":"Not-Related"}
+{"text":"Quetiapine was assayed in biological specimens by basic extraction with n-butyl chloride and derivatized with 50 microL of MTBSTFA and separation by GC-NPD.","label":0,"label_text":"Not-Related"}
+{"text":"These four cases, with their varied presenting symptoms, clinical courses, and degree of pathology, emphasize the importance of considering toxic leukoencephalopathy as an etiology of acute neurologic deterioration following high-dose chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"After initial parenteral vancomycin and rifampin followed by oral prystinamycin-rifampin, the patient recovered without any sequelae.","label":0,"label_text":"Not-Related"}
+{"text":"In addition, an immediate erythematous macule was observed on the photopatch test site of mequitazine directly after UV exposure which was similar to the immediate erythema noted in chlorpromazine photoallergy.","label":1,"label_text":"Related"}
+{"text":"Cat-scratch disease, primarily caused by Bartonella henselae, typically presents with regional adenopathy, and the role of antibiotics in the treatment is debatable.","label":0,"label_text":"Not-Related"}
+{"text":"Nocardial brain abscess in a renal transplant recipient successfully treated with triple antimicrobials.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Topiramate may be associated with ciliochoroidal effusion with forward displacement of the lens-iris diaphragm and anterior chamber shallowing, resulting in acute myopia and angle-closure glaucoma.","label":1,"label_text":"Related"}
+{"text":"Continuous subcutaneous infusion was well tolerated and about 80 per cent as effective as intravenous therapy in chelating iron.","label":0,"label_text":"Not-Related"}
+{"text":"Unexpectedly high toxicity of MACOP-B in young patients with low grade lymphoma.","label":0,"label_text":"Not-Related"}
+{"text":"The relevant literature is reviewed and supports the claim that the lithium ion may be nephrotoxic.","label":0,"label_text":"Not-Related"}
+{"text":"The combinations of clinical manifestations among FMF patients are quite heterogeneous, but our American cohort did not establish any connections between individual mutations and specific clinical pictures--as is seen in other diseases like cystic fibrosis, in which distinct genotypes target certain organ systems.","label":0,"label_text":"Not-Related"}
+{"text":"We report two patients who developed intense livedo reticularis clearly related to the administration of interferon alpha 2b as an adjuvant therapy for melanoma.","label":1,"label_text":"Related"}
+{"text":"Despite these antithrombotic effects, the patient developed repeated venous thromboembolism during treatment with low-molecular-weight heparin.","label":1,"label_text":"Related"}
+{"text":"Salmonellosis in dogs with lymphosarcoma.","label":0,"label_text":"Not-Related"}
+{"text":"Physicians should remain alert to the potential hazards of chemotherapy to the central nervous system.","label":0,"label_text":"Not-Related"}
+{"text":"We report four cases of encephalopathy coincident with elevated aluminum levels as well as one patient who developed seizures while receiving continuous bladder irrigations with alum.","label":1,"label_text":"Related"}
+{"text":"On day 14, itraconazole solution at a dose of 5 mg\/kg was begun.","label":0,"label_text":"Not-Related"}
+{"text":"In both cases, the psychiatric disorder was safely resolved with electroconvulsive therapy (ECT) during anticoagulant therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Except for one episode of grade 4 leucopenia which required hospitalization and granulocyte colony-stimulating factor (GCSF) treatment, all adverse events resolved with dose reduction or dose omission.","label":0,"label_text":"Not-Related"}
+{"text":"The occurrence of neuromuscular blockade and the resulting potentiation of muscle relaxants during magnesium sulfate (MgSO4) administration is well known.","label":1,"label_text":"Related"}
+{"text":"Review of the literature and report of a case following irradiation and cytostatic therapy.","label":0,"label_text":"Not-Related"}
+{"text":"A 30-year-old woman died as a result of a large Candida parapsilosis septic thrombus located on the tip of a Groshong catheter.","label":0,"label_text":"Not-Related"}
+{"text":"Both patients underwent cerebrospinal fluid shunting mainly for their hydrocephalus.","label":0,"label_text":"Not-Related"}
+{"text":"Rosaceiform eruption induced by erlotinib.","label":1,"label_text":"Related"}
+{"text":"Two cases of polyarteritis nodosa and one case of pityriasis rosea-like drug eruption.","label":0,"label_text":"Not-Related"}
+{"text":"Several authors have speculated bacteraemic patient without having meningitis LP might actually cause meningitis.","label":0,"label_text":"Not-Related"}
+{"text":"Action of intracoronary nitroglycerin in refractory coronary artery spasm.","label":0,"label_text":"Not-Related"}
+{"text":"SD-OCT irregularities in the IS\/OS junction were also seen in areas not detected on HVF 10-2.","label":0,"label_text":"Not-Related"}
+{"text":"This report presents a case of colon perforation which occurred 4 months after treatment with intraperitoneal chromic phosphate for stage IB ovarian papillary serous cystadenocarcinoma.","label":1,"label_text":"Related"}
+{"text":"Subsequent management with topical steroids was complicated as the patient was a steroid responder and developed a markedly raised intraocular pressure that was managed with a topical anti-glaucoma agent.","label":0,"label_text":"Not-Related"}
+{"text":"Alternative methods for conversion of supraventricular tachycardia should be considered.","label":0,"label_text":"Not-Related"}
+{"text":"We caution against abrupt interruption of anticholinergics in patients with severe segmental cranial dystonia, even in those cases in which no benefit is apparent to observers.","label":0,"label_text":"Not-Related"}
+{"text":"In one patient, interferon induced hypothyroidism in the absence of pre-existing thyroid dysfunction and in the other it aggravated a pre-existing thyroid dysfunction.","label":0,"label_text":"Not-Related"}
+{"text":"In this paper, the authors report 3 cases of children under three years of age, with a presumed diagnosis of PNET\/MB, who were preoperatively treated with chemotherapy consisting of high doses of carboplatin alone.","label":0,"label_text":"Not-Related"}
+{"text":"Frequent blood glucose monitoring is recommended in children on prolonged therapy with glucocorticoids.","label":0,"label_text":"Not-Related"}
+{"text":"Diagnosis was confirmed by 16S ribosomal RNA gene sequencing of bacterial colonies growing from the extracted device.","label":0,"label_text":"Not-Related"}
+{"text":"Intravenous bisphosphonates have come into increasing use to protect cancer patients from adverse boney events.","label":0,"label_text":"Not-Related"}
+{"text":"Abdominal pain deteriorated early in the course of the therapy along with the enlargement of the tumors.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Findings of HLA typing revealed positive reaction for B 51, Cw 3, DR 8, DR 11, DQ 3.","label":0,"label_text":"Not-Related"}
+{"text":"On MRI, the low and high signal areas near the end-plate of L5\/S1 were detected by T1- and T2-weighted imaging, respectively, and an abscess was noted around the cage.","label":0,"label_text":"Not-Related"}
+{"text":"Polymyositis after propylthiouracil treatment for hyperthyroidism.","label":1,"label_text":"Related"}
+{"text":"Non-nucleoside retroviral transcriptase inhibitors are known to cause hepatotoxicity.","label":0,"label_text":"Not-Related"}
+{"text":"Glucocorticoids may have many side effects, and therefore their use should always be carefully considered.","label":0,"label_text":"Not-Related"}
+{"text":"Thus, an increase in lactate concentration of the magnitude observed during alkali therapy need not indicate a worsening of the metabolic picture in lactic acidosis.","label":0,"label_text":"Not-Related"}
+{"text":"During prolonged treatment with zanamivir, a mutant virus was isolated from an immunocompromised child infected with influenza B virus.","label":0,"label_text":"Not-Related"}
+{"text":"He presented with hypokalemia and hyperchloremic non-anion-gap metabolic acidosis with a high urinary pH.","label":0,"label_text":"Not-Related"}
+{"text":"Sarcoidosis is a chronic granulomatous multisystemic disorder of unknown aetiology.","label":0,"label_text":"Not-Related"}
+{"text":"Three patients with human immunodeficiency virus (HIV) infection presented with QT, prolongation (> 440 ms) and torsades de pointes.","label":0,"label_text":"Not-Related"}
+{"text":"A 53-year-old female was admitted to hospital one hour after taking an overdose of 60 g of paracetamol and 960 mg of codeine.","label":0,"label_text":"Not-Related"}
+{"text":"Three patients with niacin-induced visual symptoms had cystoid maculopathy without leakage on fluorescein angiography, and a fourth patient with no fundus abnormality experienced cessation of visual symptoms upon discontinuation of niacin.","label":1,"label_text":"Related"}
+{"text":"The most common cutaneous adverse event is an acneiform eruption, which occurs in more than 50% of cases.","label":0,"label_text":"Not-Related"}
+{"text":"Hemoglobin electrophoresis and methemoglobin reductase determinations were normal for age.","label":0,"label_text":"Not-Related"}
+{"text":"Eight patients reported a 'high'; six denied a 'high'.","label":0,"label_text":"Not-Related"}
+{"text":"It occurs more frequently in women with underlying systemic autoimmune disease and after multiple ocular procedures.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Three patients with histories of impotence experienced a return of sexual potency after treatment with fluoxetine.","label":0,"label_text":"Not-Related"}
+{"text":"Attenuation of drug-induced anxiety dreams and pavor nocturnus by benzodiazepines.","label":0,"label_text":"Not-Related"}
+{"text":"Insulin resistance declined with adrenal suppression and infection control, and wound healing improved dramatically.","label":0,"label_text":"Not-Related"}
+{"text":"To date, stent fractures reported have been related to aggressive post dilation.","label":0,"label_text":"Not-Related"}
+{"text":"This case extends the spectrum of fludarabine pulmonary toxicity to include pulmonary nodules.","label":1,"label_text":"Related"}
+{"text":"At the time of death, leukocytes were 0.3 x 10(3)\/mm(3), platelets 10 x 10(3)\/mm(3), and hemoglobin 6.8 mg\/dL.","label":0,"label_text":"Not-Related"}
+{"text":"Palmar-plantar erythrodysaesthesia (PPE) is an uncommon cutaneous complication of cytotoxic chemotherapy which generally presents as a painful erythema involving the palms and soles.","label":0,"label_text":"Not-Related"}
+{"text":"IVIg may reverse and stabilize the inflammatory process.","label":0,"label_text":"Not-Related"}
+{"text":"Five cases are presented that demonstrate the effectiveness of diazepam and its close relative clorazepate in controlling this problem.","label":0,"label_text":"Not-Related"}
+{"text":"Patients in whom CSC develops while using corticosteroid inhalers or nasal sprays should be alerted to the possible relationship between CSC and these agents.","label":0,"label_text":"Not-Related"}
+{"text":"Upon discontinuation of MTX, her ascites resolved, and her arthritis became more active.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: Laser in situ keratomileusis can be complicated by Acanthamoeba infection.","label":0,"label_text":"Not-Related"}
+{"text":"In case #1, the concentrations of quetiapine found were 7.20 mg\/L (19 micromol\/L) in blood and 0.93 mg\/L (2.4 micromol\/L) in vitreous fluid.","label":0,"label_text":"Not-Related"}
+{"text":"In vitro inhibition of hematopoiesis in a patient with systemic sclerosis treated with D-penicillamine.","label":1,"label_text":"Related"}
+{"text":"OBJECTIVE: To report the case of a young woman with Graves' disease in whom ototoxicity developed because of propylthiouracil (PTU)-induced antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis.","label":1,"label_text":"Related"}
+{"text":"Six consecutive patients with HIV infection and NCPH were the subject of this series.","label":0,"label_text":"Not-Related"}
+{"text":"A 21-year-old woman suffering from bipolar affective disorder developed systemic lupus erythematosus (SLE) with characteristic laboratory findings, 18 months after starting carbamazepine maintenance treatment.","label":1,"label_text":"Related"}
+{"text":"She was initially managed with palliative nephrectomy, which was followed by rapid postoperative deterioration.","label":0,"label_text":"Not-Related"}
+{"text":"Posterior leukoencephalopathy following cisplatin, bleomycin and vinblastine therapy for germ cell tumor of the ovary.","label":1,"label_text":"Related"}
+{"text":"RESULTS: Only when the antidepressant was removed, twice, was treatment an atypical antipsychotic and lithium effective.","label":0,"label_text":"Not-Related"}
+{"text":"Patients experienced a mean reduction of 92% (a mean drop in frequency of 21.7 to 1.7 episodes per week).","label":0,"label_text":"Not-Related"}
+{"text":"Linear IgA disease (LAD) is characterized by circulating and tissue-bound IgA antibodies against heterogeneous antigens in the cutaneous basement membrane zone.","label":0,"label_text":"Not-Related"}
+{"text":"In the present paper, we describe two patients with active UC who developed a severe systemic CMV infection during a treatment with an oral microemulsion form of cyclosporine.","label":1,"label_text":"Related"}
+{"text":"Autologous bone marrow transplantation in relapsed HIV-related non-Hodgkin's lymphoma.","label":0,"label_text":"Not-Related"}
+{"text":"The plasma concentrations of the active metabolite M6G were more than 10 times those normally seen and the half-lives of M6G and morphine were prolonged.","label":0,"label_text":"Not-Related"}
+{"text":"Although major hazards of treatment of hypophosphatemic osteomalacia with phosphate and calcitriol are secondary hyperparathyroidism and vitamin D intoxication, potassium loss also should be kept in mind.","label":1,"label_text":"Related"}
+{"text":"She improved with administration of diazepam, but needed repetition of this treatment over the next 16 hours.","label":0,"label_text":"Not-Related"}
+{"text":"Its immunomodulatory properties, however, may allow its future use in the treatment of psoriasis.","label":0,"label_text":"Not-Related"}
+{"text":"In one case, the readministration of riluzole was followed by the relapse of hepatitis.","label":1,"label_text":"Related"}
+{"text":"A mild decrease in the temperature (33.4-34.7 degrees C) along with delusions and feeling slightly chilly was part of the initial presentation.","label":0,"label_text":"Not-Related"}
+{"text":"He was referred to the psychiatry service where he was treated with olanzapine.","label":0,"label_text":"Not-Related"}
+{"text":"SMS 201-995 was also effective in suppressing thyroid-stimulating hormone (TSH) and thyroid hormone secretion in a patient with mild thyrotoxicosis due to non-tumoural inappropriate TSH hypersecretion.","label":0,"label_text":"Not-Related"}
+{"text":"The typical fluoxetine-induced symptoms of restlessness, constant pacing, purposeless movements of the feet and legs, and marked anxiety were indistinguishable from those of neuroleptic-induced akathisia.","label":1,"label_text":"Related"}
+{"text":"This may be related to individual variations in cerebrospinal fluid dynamics and drug metabolism.","label":0,"label_text":"Not-Related"}
+{"text":"This unusual pattern of low-grade endometrial carcinoma adds to the spectrum of uterine neoplasia associated with tamoxifen therapy.","label":1,"label_text":"Related"}
+{"text":"Generalized argyria, the systemic dissemination and tissue deposition of silver-containing particles, is characterized by slate gray discoloration of skin, most pronounced in sun exposed areas.","label":0,"label_text":"Not-Related"}
+{"text":"An increase of intoxications in persons using alkaloid-containing ornamental plants (mainly angel's trumpet) for their hallucinogenic effects and easy and cheap availability is registered.","label":0,"label_text":"Not-Related"}
+{"text":"Differentiation and treatment can be complex, especially when features of both syndromes are present and the patient has taken both serotonergic and neuroleptic agents.","label":0,"label_text":"Not-Related"}
+{"text":"Human coenurosis in North America: case reports and review.","label":0,"label_text":"Not-Related"}
+{"text":"As Paget (1988) says, \"The sorrow of mistakes is sometimes very diffuse and sometimes very pointed.","label":0,"label_text":"Not-Related"}
+{"text":"Intravitreal injection of triamcinolone acetonide is useful in the treatment of macular edema; however, accumulation of triamcinolone acetonide particles on the posterior lens capsule may decrease visual acuity and requires surgical treatment.","label":0,"label_text":"Not-Related"}
+{"text":"A dapsone hypersensitivity syndrome, consisting of fever, headache, nausea, vomiting, lymphadenopathy, hepatitis, hemolysis, leukopenia, and mononucleosis, has been described in patients treated with the drug for leprosy.","label":1,"label_text":"Related"}
+{"text":"In both cases, high fever, skin rash, liver dysfunction and atypical lymphocytosis developed 3 weeks after initiating treatment with SASP.","label":1,"label_text":"Related"}
+{"text":"Physicians in the United States, especially those who practice primary care, hematology\/oncology, and infectious diseases, must be aware of the availability and use of metamizole in specific patient populations and its potential for harmful side effects.","label":0,"label_text":"Not-Related"}
+{"text":"An infant girl with choanal atresia, athelia, minor anomalies, and mild to moderate mental retardation was born to a woman treated for hyperthyroidism throughout pregnancy with methimazole and propranolol.","label":1,"label_text":"Related"}
+{"text":"After exclusion of common reasons of this condition, liver biopsy was performed.","label":0,"label_text":"Not-Related"}
+{"text":"Nocardiosis revealed by thyroid abscess in a liver--kidney transplant recipient.","label":0,"label_text":"Not-Related"}
+{"text":"Subfoveal choroidal neovascularization in a patient with hemicentral vein occlusion.","label":0,"label_text":"Not-Related"}
+{"text":"Her IFN beta-1a was discontinued and intravenous immunoglobulin therapy was started for her scleromyxedema.","label":0,"label_text":"Not-Related"}
+{"text":"We observed a 7.0% prevalence of QT, prolongation among all patients screened.","label":0,"label_text":"Not-Related"}
+{"text":"Both serum hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (HBsAb) were negative on admission.","label":0,"label_text":"Not-Related"}
+{"text":"They were both treated for stage IV neuroblastoma with chemotherapy, bone marrow transplant (BMT) conditioning that included total body irradiation and RA therapy after BMT, although the patient in case 1 had established renal insufficiency prior to the commencement of RA.","label":0,"label_text":"Not-Related"}
+{"text":"Initially, she responded well to corticosteroids, but relapsed when medication was discontinued.","label":0,"label_text":"Not-Related"}
+{"text":"Patient A reported right leg weakness (foot drop) during week 4 of CAP-XRT (1600 mg\/m2).","label":1,"label_text":"Related"}
+{"text":"Antibiotic treatment did not stop the progress of the disease.","label":0,"label_text":"Not-Related"}
+{"text":"The most frequent pathological finding is myocardial haemorrhage, with no evidence of coronary artery atheroma or thrombosis.","label":0,"label_text":"Not-Related"}
+{"text":"Biological data mainly revealed hepatic failure and lactic acidosis.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: Three infants were treated with clobetasol propionate (Temovate) cream for vision-threatening eyelid hemangiomas.","label":0,"label_text":"Not-Related"}
+{"text":"Lichen nitidus is an uncommon dermatosis of unknown etiology.","label":0,"label_text":"Not-Related"}
+{"text":"Transrectal ultrasound-guided needle biopsy of the prostate is a widely accepted technique to obtain prostatic tissue for histological examination.","label":0,"label_text":"Not-Related"}
+{"text":"We present a severe case of TPP in a 22-year-old Latino male with rapidly progressive ascending paralysis and hypokalemia severe enough to lead to cardiac arrest.","label":0,"label_text":"Not-Related"}
+{"text":"Histological changes after the use of mycophenolate mofetil in autoimmune hepatitis.","label":0,"label_text":"Not-Related"}
+{"text":"She subsequently underwent successful cardiac transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"Physician awareness of the occurrence of a variety of muscle disorders including polymyositis in thyroid disease is emphasised.","label":0,"label_text":"Not-Related"}
+{"text":"However, there was clinical and electrophysiologic recovery after initiation of intravenous immunoglobulin (IVIg) therapy.","label":0,"label_text":"Not-Related"}
+{"text":"We present a patient with typical aquagenic pruritus who responded well to PUVA, and who has remained well controlled on infrequent maintenance.","label":0,"label_text":"Not-Related"}
+{"text":"Acute endophthalmitis following intravitreal bevacizumab (Avastin) injection.","label":1,"label_text":"Related"}
+{"text":"To know the histochemical effects of steroid treatment on eosinophil accumulation in nasal polyps of AIA and the histochemical feature of a recurring polyp and to detect distributional differences between storage and secreted forms of eosinophil cationic proteins, we carried out immunocytochemical labelling with antibodies against EGI (recognizing resting and activated eosinophils) and EG2 (recognizing only activated eosinophils), and determined eosinophil infiltration in nasal polyps that were obtained before and after steroid treatment, and at recurrence of polyps.","label":0,"label_text":"Not-Related"}
+{"text":"Five patients were treated with isoprinosine and the antiepileptic drug valproic acid.","label":0,"label_text":"Not-Related"}
+{"text":"Maintaining a high index of suspicion with early recognition and aggressive therapy may decrease the morbidity and mortality of this devastating and life-threatening infection in the compromised host.","label":0,"label_text":"Not-Related"}
+{"text":"These effects are mainly due to the thrombolysis of macroscopic blood clots and the amelioration of microcirculatory reperfusion.","label":0,"label_text":"Not-Related"}
+{"text":"After a second dose of metoclopramide, these symptoms recurred and were associated with confusion, agitation, fever, diaphoresis, tachypnea, tachycardia, and hypertension.","label":1,"label_text":"Related"}
+{"text":"Patients did not show any local recurrence after 1 year.","label":0,"label_text":"Not-Related"}
+{"text":"Clinicians should be aware of the possibility that vinorelbine may cause SIADH and possibly hypokalemia.","label":1,"label_text":"Related"}
+{"text":"Kluyvera species are opportunistic, gram-negative bacilli in the family Enterobacteriaceae.","label":0,"label_text":"Not-Related"}
+{"text":"Reports of colonic perforation as a result of the administration of calcium polystyrene sulfonate and sorbitol are rare.","label":1,"label_text":"Related"}
+{"text":"RESULTS: Histopathology revealed a subcorneal blister with prominent neutrophilic infiltration.","label":0,"label_text":"Not-Related"}
+{"text":"Anticoagulation was maintained and the prognosis remained good.","label":0,"label_text":"Not-Related"}
+{"text":"All 3 patients received rituximab according to a standardized institutional rate schedule, and all received pre-medication with acetaminophen and diphenhydramine.","label":0,"label_text":"Not-Related"}
+{"text":"Portal vein thrombosis during antineoplastic chemotherapy in children: report of five cases and review of the literature.","label":0,"label_text":"Not-Related"}
+{"text":"PURPOSE: To report the clinical course, management, and outcome of infectious interface keratitis caused by mycobacterium species after laser in situ keratomileusis (LASIK).","label":0,"label_text":"Not-Related"}
+{"text":"AIM: Report of a case of a woman patient who developed celiac disease after pegylated interferon alpha-2a and ribavirin use for chronic hepatitis C.","label":1,"label_text":"Related"}
+{"text":"The oral mucosa, tongue, sclera, and conjunctiva also had a slightly blue-gray discoloration.","label":0,"label_text":"Not-Related"}
+{"text":"Pharmacokinetics of daptomycin in a critically ill adolescent with vancomycin-resistant enterococcal endocarditis.","label":0,"label_text":"Not-Related"}
+{"text":"Upper tract urothelial malignancy after cyclophosphamide therapy: a case report and literature review.","label":1,"label_text":"Related"}
+{"text":"It should be considered for use before benzoin because once allergy to benzoin exists, cross-reactions to Mastisol usually occur.","label":0,"label_text":"Not-Related"}
+{"text":"During the treatment of hematological malignancies this could be a cause of great concern.","label":0,"label_text":"Not-Related"}
+{"text":"An awareness of this potential complication is important when treating children with aspirin at doses previously considered to be non-toxic.","label":0,"label_text":"Not-Related"}
+{"text":"Gold and sulfur could not be demonstrated in glomerular epimembranous deposits.","label":0,"label_text":"Not-Related"}
+{"text":"Vincristine levels were also assayed and showed a dramatic decline in postexchange levels in the 2 patients who survived and an almost unchanged value in the patient who succumbed.","label":0,"label_text":"Not-Related"}
+{"text":"Initial presentation was adnexial mass and chronic pelvic pain.","label":0,"label_text":"Not-Related"}
+{"text":"Clinicians need to be aware of this rare but potentially fatal side effect in patients of all ages, and especially in adolescents receiving both drugs.","label":0,"label_text":"Not-Related"}
+{"text":"Clinical observations were examined retrospectively for three cases with adverse reactions and cited to support a dynamic theory that associated drug reactivity to personality factors.","label":0,"label_text":"Not-Related"}
+{"text":"Discontinuation of levamisole and 5-FU for a five-week period resulted in the INR falling to a subtherapeutic level.","label":0,"label_text":"Not-Related"}
+{"text":"A drug-drug interaction may result in decreased methadone blood levels when administered with nevirapine.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: Ten patients with long standing primary CBCL (3 with follicular CBCL, 5 with cutaneous, large B-cell lymphoma, 1 with diffuse large cell lymphoma, and 1 with extranodal large cell lymphoma) were treated by intravenous application of a chimeric antibody against the CD20 transmembrane antigen that is present on malignant and normal B-cells.","label":0,"label_text":"Not-Related"}
+{"text":"A case of barbiturate-induced submassive hepatic necrosis is presented and the literature is reviewed.","label":1,"label_text":"Related"}
+{"text":"A 48-year-old woman with multiple myeloma, developed progressive neurological disturbances one year after the bone marrow remission.","label":0,"label_text":"Not-Related"}
+{"text":"A 12 year old patient with atrial flutter is presented, in whom intravenous adenosine was followed by acceleration of the heart rate to a potentially dangerous arrhythmia.","label":1,"label_text":"Related"}
+{"text":"Treatment for 1 year or longer decreased tumor secretion of gastrin and diminished basal acid secretion, an effect that persisted for 48 hours after withdrawal of SMS.","label":0,"label_text":"Not-Related"}
+{"text":"When side effects recurred the dosage was reduced further by 50%.","label":0,"label_text":"Not-Related"}
+{"text":"Myoclonus is a movement disorder of various etiologies.","label":0,"label_text":"Not-Related"}
+{"text":"This entity is probably related to a combination of high doses of corticosteroids, vecuronium administration and metabolic abnormalities associated with respiratory failure.","label":1,"label_text":"Related"}
+{"text":"Neither mosaic perfusion nor air-trapping was seen in HRCT on inspiration and expiration.","label":0,"label_text":"Not-Related"}
+{"text":"In this healthy population, the relative risk of developing endometrial carcinoma in the tamoxifen arm was 2.54, although when stratified by age, in women over 50, the risk grew to 4.01.","label":1,"label_text":"Related"}
+{"text":"No organisms could be grown by culture of corneal scrapings for bacteria and fungi, and the condition failed to respond to topical therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Endocrine physicians should be alert to this in patients with fixed DI and an abnormal thirst threshold.","label":0,"label_text":"Not-Related"}
+{"text":"Recurrent aortic valve prosthesis dehiscence secondary to aortoarteritis: three case reports and literature review.","label":0,"label_text":"Not-Related"}
+{"text":"It is concluded that 'cerebral atrophy' on CT scans may represent an accumulative effect of ACTH and that ACTH should be given with the utmost discretion, and in as low a dose as possible.","label":1,"label_text":"Related"}
+{"text":"Conversely, diffuse interstitial pulmonary fibrosis should be considered in the differential diagnosis of patients receiving methotrexate who develop bilateral pulmonary infiltrates seen on chest roentgenograms.","label":1,"label_text":"Related"}
+{"text":"We report a case in which in-stent restenosis of an overhanging stent had been treated with an also overhanging sirolimus-coated Cypher stent (Cordis Corporation, Roden, The Netherlands).","label":0,"label_text":"Not-Related"}
+{"text":"Two years after HSCT, the patient developed nephrotic syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: As a result of recent tyramine analyses and 2 well-documented case reports, all tap (draft) beers should now be absolutely restricted on MAOI diets because they represent a very significant risk at modest levels of consumption.","label":0,"label_text":"Not-Related"}
+{"text":"Hepatitis C (HCV) treatment using interferon-alpha (IFN-alpha) and ribavirin is recommended in HIV\/HCV co-infected patients to prevent liver cirrhosis and liver-related death.","label":0,"label_text":"Not-Related"}
+{"text":"Prior to surgery, levodopa induced dyskinesia had improved (< or = 50%) under treatment with amantadine (400 mg\/day, po) in all three patients.","label":1,"label_text":"Related"}
+{"text":"Continuous high-dose intracoronary nitroglycerin infusion in refractory coronary vasospasm.","label":0,"label_text":"Not-Related"}
+{"text":"Acute coronary syndrome induced by capecitabine therapy.","label":1,"label_text":"Related"}
+{"text":"She was treated with intramuscular injections of methotrexate 20 mg\/wk.","label":0,"label_text":"Not-Related"}
+{"text":"In an effort to destroy verrucous growth, the authors have attempted to alter the genetic structure of these obstinate, benign warty lesions by using the antibiotic, bleomycin sulfate.","label":0,"label_text":"Not-Related"}
+{"text":"Posterior leukoencephalopathy following intrathecal chemotherapy with MRA-documented vasospasm.","label":0,"label_text":"Not-Related"}
+{"text":"All 4 patients who were recruited completed the procedure successfully without significant difficulty.","label":0,"label_text":"Not-Related"}
+{"text":"Potential causes of methamphetamine-related keratitis can be divided into four categories resulting from (a) direct pharmacologic and physical effects of methamphetamine; (b) the toxic effects of diluting or \"cutting\" agents such as lidocaine and quinine; (c) effects related to the route of drug administration (intravenous, inhalation, smoking); and (d) manufacture-related effects of exposure to unintentional caustic contaminants in the final product.","label":1,"label_text":"Related"}
+{"text":"Oxaliplatin is a new platinum derivative that has significant activity in patients with metastatic colorectal carcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"At the bedside, nurses play a pivotal role in early recognition and treatment, the key to survival.","label":0,"label_text":"Not-Related"}
+{"text":"In addition, she required additive reductions of 33-42% in her weekly warfarin dose with each chemotherapy cycle to maintain a therapeutic INR (goal range 2.0-3.0).","label":0,"label_text":"Not-Related"}
+{"text":"The findings are based on liver histology and the exclusion of other causes of liver damage.","label":0,"label_text":"Not-Related"}
+{"text":"Benzocaine, an ester-type local anesthetic, was believed responsible for apparent methemoglobinemia in a cat.","label":1,"label_text":"Related"}
+{"text":"CASE SUMMARY: An elderly patient with chronic atrial fibrillation and prosthetic valve replacements had been taking warfarin 22.5 mg\/wk.","label":0,"label_text":"Not-Related"}
+{"text":"Liver function tests (LFT) returned to normal within five days of hospitalization but she continued to develop daily fevers.","label":0,"label_text":"Not-Related"}
+{"text":"Flumazenil reversal of benzodiazepine-induced sedation for a patient with severe pre-ECT anxiety.","label":1,"label_text":"Related"}
+{"text":"We describe a case of disseminated muscular cysticercosis followed by myositis (fever, diffuse myalgia, weakness of the lower limbs, and inflammatory reaction around dying cysticerci) induced by praziquantel therapy, an event not described previously.","label":1,"label_text":"Related"}
+{"text":"METHODS: The patient was a 20-year-old woman.","label":0,"label_text":"Not-Related"}
+{"text":"In addition to its antiviral action, ribavirin also enhances the Th1 response.","label":0,"label_text":"Not-Related"}
+{"text":"SIADH appeared to be transient and asymptomatic in our patients.","label":0,"label_text":"Not-Related"}
+{"text":"The results clearly demonstrate that CPH82 was associated with suppression of the endogeneous production of ACTH and cortisol with a concomitant paradoxical picture of clinical hypercortisolism.","label":1,"label_text":"Related"}
+{"text":"She was admitted to the hospital for persistent vomiting.","label":0,"label_text":"Not-Related"}
+{"text":"Acute transverse myelitis is an acute inflammatory process of the spinal cord and it is a rare clinical syndrome in childhood.","label":0,"label_text":"Not-Related"}
+{"text":"In addition, this case underscores the importance of communication between physician and patient and the resulting toxicity related to miscommunication.","label":0,"label_text":"Not-Related"}
+{"text":"The fluorine contained in niflumic acid induced a marked densification of trabecular bone in all 3 cases.","label":1,"label_text":"Related"}
+{"text":"The autopsy findings and a detailed medical history supported the conclusion that clozapine-induced hypersensitivity myocarditis was the most likely cause of death.","label":1,"label_text":"Related"}
+{"text":"Clinical evidence of vena cava thrombosis and associated spontaneous intraventricular hemorrhage developed on Day 24 and 36, respectively, and these findings were confirmed on imaging studies.","label":0,"label_text":"Not-Related"}
+{"text":"This entity should be added to the group of conditions, both infectious and noninfectious, that cause diffuse pulmonary uptake on labeled leukocyte images.","label":0,"label_text":"Not-Related"}
+{"text":"A case report is presented of a bulimic patient with manic symptoms who was successfully treated with lithium.","label":0,"label_text":"Not-Related"}
+{"text":"METHOD: We describe two patients who presented with diabetic ketoacidosis after treatment with quetiapine and risperidone, respectively.","label":1,"label_text":"Related"}
+{"text":"Pain partially responsive to opioids can lead to rapid escalating dosages due to tolerance development.","label":0,"label_text":"Not-Related"}
+{"text":"With the diagnosis of therapy-related acute myeloid leukemia (AML) secured, he began induction chemotherapy with idarubicin and cytarabine.","label":0,"label_text":"Not-Related"}
+{"text":"Following removal of a large right adrenal carcinoma, serum and urinary hormone levels returned to normal.","label":0,"label_text":"Not-Related"}
+{"text":"Despite extensive surveillance, an infectious cause for the heart failure was not found while he was alive.","label":0,"label_text":"Not-Related"}
+{"text":"Two of the patients (1 and 3) are from a multicentre trial of adjuvant chemotherapy for gastric carcinoma.","label":0,"label_text":"Not-Related"}
+{"text":"Nevertheless, it is increasingly recognized as a complication of therapy in solid tumors.","label":0,"label_text":"Not-Related"}
+{"text":"Sirolimus (rapamycin) and everolimus are immunosuppressive agents that inhibit cardiac allograft vasculopathy.","label":0,"label_text":"Not-Related"}
+{"text":"A chest X ray showed infiltrates in right upper lobe with bilateral pleural effusion.","label":0,"label_text":"Not-Related"}
+{"text":"Three demented patients who manifested an aggressive syndrome and motor disturbances including agitation, pacing, and restlessness received a therapeutic trial of the antiandrogen agents medroxyprogesterone acetate and luprolide acetate.","label":0,"label_text":"Not-Related"}
+{"text":"Previously reported cases are reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"Gold nephropathy due to auranofin obscured by tolmetin pseudoproteinuria.","label":1,"label_text":"Related"}
+{"text":"The aim of this phase I study was to determine the toxicity profile and the optimal dosage of KW-2149.","label":0,"label_text":"Not-Related"}
+{"text":"Esophageal spasm is an infrequent complication of beta-adrenergic over-dose.","label":0,"label_text":"Not-Related"}
+{"text":"This case presents a patient with neuropathic pain in a lower extremity, which appeared subsequent to the removal of a C1 meningioma and which was successfully treated by lower thoracic spinal cord stimulation.","label":0,"label_text":"Not-Related"}
+{"text":"This case is reminiscent of pneumonitis to other beta-blockers, which are reviewed here.","label":0,"label_text":"Not-Related"}
+{"text":"Fever in dialysis patients with recently rejected renal allografts.","label":0,"label_text":"Not-Related"}
+{"text":"Vital signs were within normal limits.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: We found a slightly reduced visual acuity, a slowly increasing amount of yellow-white deposits on the posterior surface of the cornea and on the anterior part of the lens, a normal fundus appearance, and normal visual fields.","label":0,"label_text":"Not-Related"}
+{"text":"Acute lung injury associated with 5-fluorouracil and oxaliplatinum combined chemotherapy.","label":1,"label_text":"Related"}
+{"text":"Disseminated salmonellosis in a patient treated with temozolomide.","label":1,"label_text":"Related"}
+{"text":"Hyperglycemia induced by the first product improved after the substitution, suggesting that the Erwinia enzyme may be less diabetogenic than the E. coli enzyme.","label":0,"label_text":"Not-Related"}
+{"text":"Aspiration of bone marrow with use of clot sections is a minimally invasive, sensitive, and rapid means of detecting granulomatous infection in such febrile immunosuppressed hosts.","label":0,"label_text":"Not-Related"}
+{"text":"Thirteen patients highly allergic to mechlorethamine hydrochloride showed no cross-sensitivity to nitrosourea compounds.","label":0,"label_text":"Not-Related"}
+{"text":"Therefore, we diagnosed her eruption as contact dermatitis due to sodium bisulfite.","label":1,"label_text":"Related"}
+{"text":"Since carbamazepine was discontinued and had been prescribed for bipolar disorder, his olanzapine dosage was increased, and trazodone was added at bedtime for insomnia.","label":0,"label_text":"Not-Related"}
+{"text":"The break was successfully closed with an intraoperative injection of Healon5 into the bleb.","label":0,"label_text":"Not-Related"}
+{"text":"Our patient developed both nephrogenic diabetes insipidus and renal tubular acidosis with a temporal pattern that demonstrated a link between foscarnet therapy and these abnormalities.","label":1,"label_text":"Related"}
+{"text":"A successful clinical outcome was achieved upon recognition of the fungal pathogen.","label":0,"label_text":"Not-Related"}
+{"text":"The disk diffusion method showed that this Norcardia sp. was sensitive to many antibiotics.","label":0,"label_text":"Not-Related"}
+{"text":"After one fall, the patient became delirious.","label":0,"label_text":"Not-Related"}
+{"text":"The infection was successfully treated with flap amputation and daily debridement in addition to antifungal therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Asthma is a chronic inflammatory condition of the airway, characterised by the presence of airflow obstruction which is variable over short periods of time, or is reversible with treatment.","label":0,"label_text":"Not-Related"}
+{"text":"The incidence of cerebellar toxicity approaches 30 percent, with irreversible ataxia reported in up to 16.7 percent.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a 20-year-old woman who presented with polyarthralgia and sensory neuropathy, including mental nerve neuropathy.","label":0,"label_text":"Not-Related"}
+{"text":"Possible long-term teratogenic effect of isotretinoin in pregnancy.","label":0,"label_text":"Not-Related"}
+{"text":"Aripiprazole combined with low-dose clozapine as maintenance therapy resulted in a positive clinical outcome despite a clozapine serum level that is generally considered subtherapeutic.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Clinicians should be aware that removing a serotonin-2a (S-HT2a) antagonist 1mm a treatment regimen including an agent that increases serotonin in the synaptic cleft may worsen clozapine withdrawal or potentially result in serious adverse drug reactions, such as serotonin syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Sixteen hours after the first administration of IFN, IFN was suspended by the symptoms of congestive heart failure (CHF).","label":1,"label_text":"Related"}
+{"text":"We encountered two girls with acute promyelocytic leukemia (APL) after living donor partial orthotopic liver transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"Therefore, preventive measures should be taken against colonization by Candida of the palatal mucosa and the dentures.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Prolonged exposure to itraconazole, administered either continuously or intermittently, may precipitate severe and irreversible hepatotoxic events.","label":1,"label_text":"Related"}
+{"text":"Pyomyositis was completely resolved following the surgical drainage and the antistaphylococcal antibiotic treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Acute pancreatitis after long-term 5-aminosalicylic acid therapy.","label":1,"label_text":"Related"}
+{"text":"No objective data have been presented examining this issue.","label":0,"label_text":"Not-Related"}
+{"text":"When the patient presented to our service he was taking NVP, zidovudine, and lamivudine.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVES: To describe the clinicopathologic features of 3 patients with CML who rapidly progressed from chronic phase to blast crisis while taking imatinib and to perform a review of the literature.","label":1,"label_text":"Related"}
+{"text":"The leukemia developed from 21 to 58 months (median 50 months) after the institution of chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"The advent of small-incision surgery has likely reduced the incidence of this complication to low levels.","label":0,"label_text":"Not-Related"}
+{"text":"After excluding other causes of long QT syndrome, the HCQ was suspected as the cause of her ventricular tachycardia.","label":1,"label_text":"Related"}
+{"text":"Although adverse effects are usually mild, the author reports here a case of leucocytopenia and thrombocytopenia with quetiapine treatment that required its discontinuation.","label":1,"label_text":"Related"}
+{"text":"Laboratory studies showed elevated creatine kinase, aspartate aminotransferase, alanine aminotransferase, and lactate dehydrogenase levels, as well as azotemia, hyperphosphatemia, hypocalcemia, and leukocytosis.","label":0,"label_text":"Not-Related"}
+{"text":"Abnormal behaviour consisted of elevated mood, euphoria, and increased energy in both patients, and pressure of speech and decreased need for sleep in one of them.","label":0,"label_text":"Not-Related"}
+{"text":"Observation of renal biopsy specimens by light microscopy revealed minor glomerular abnormalities.","label":0,"label_text":"Not-Related"}
+{"text":"High-dose methylprednisolone was administered for treatment of the pneumonitis.","label":0,"label_text":"Not-Related"}
+{"text":"Normal pregnancy after curative multiagent chemotherapy for choriocarcinoma with brain metastases.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: Exploratory surgery was performed to remove the mass, and histologic and microbiologic studies were conducted.","label":0,"label_text":"Not-Related"}
+{"text":"The possibility of phenytoin hypersensitivity reactions should be considered when patients receiving phenytoin have unusual symptoms, particularly fever, rash, and lymphadenopathy.","label":1,"label_text":"Related"}
+{"text":"Percutaneous transluminal coronary angioplasty (PTCA) was complicated by acute coronary artery occlusion associated with ST elevation and severe chest pain in three patients.","label":0,"label_text":"Not-Related"}
+{"text":"Further studies need to be carried out to clarify the pharmacologic differences between dual and selective 5-HT and norepinephrine reuptake inhibitors on lower urinary tract function.","label":0,"label_text":"Not-Related"}
+{"text":"Her initial clinical presentation suggested postoperative infection, but the inflammation continued to progress despite antimicrobial therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Antibodies for HIT by enzyme-linked immunosorbent assay were positive.","label":0,"label_text":"Not-Related"}
+{"text":"She was treated with 50 mg of intravenous thiamine.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: A case-note audit of all Christchurch Hospital patients with RA prescribed leflunomide between 2002 and 2006 was performed.","label":0,"label_text":"Not-Related"}
+{"text":"Our protocol might not be as efficacious in patients who are more profoundly immunocompromised, eg, bone marrow allograft recipients.","label":0,"label_text":"Not-Related"}
+{"text":"She had no history suggestive of gastroesophageal reflux, peptic ulcer, or pork allergy, and no vomiting on days when enzymes were not given.","label":0,"label_text":"Not-Related"}
+{"text":"A 39-year-old woman underwent placement of a totally implantable venous access device for chemotherapy to treat a recurrent liposarcoma of the left thigh.","label":0,"label_text":"Not-Related"}
+{"text":"She had received about seventy five units of blood at the start of 2 grams of desferrioxamine with every subsequent blood transfusion.","label":0,"label_text":"Not-Related"}
+{"text":"There was also complete regression of lymphadenomegaly.","label":0,"label_text":"Not-Related"}
+{"text":"Because patients may be unlikely to self-report alternative remedies, health care providers should specifically ask their patients about any alternative treatments they may be taking and should be knowledgeable about their toxicities.","label":0,"label_text":"Not-Related"}
+{"text":"Although the exact cause of her hemorrhagic stroke is uncertain, the hypertensive response that may have led to the hemorrhagic stroke occurred following administration of commonly used doses of vasopressor agents.","label":0,"label_text":"Not-Related"}
+{"text":"Post-transplant lymphoproliferative disorder (PTLD) in the central nervous system (CNS) has a poor prognosis.","label":0,"label_text":"Not-Related"}
+{"text":"In all three patients a decrease in anti-DNA antibody levels and an increase in total complement hemolytic activity were detected after therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Many thoracic specialists and eye care physicians consider these effects rare and readily reversible.","label":0,"label_text":"Not-Related"}
+{"text":"After 2 weeks, the thrombus had disappeared.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of hepatolithiasis (intrahepatic stone) complicated by gram-negative sepsis in a 37 year old male with acromegaly being treated with octreotide.","label":1,"label_text":"Related"}
+{"text":"Anaphylactoid shock, disseminated intravascular coagulation, and anuric renal failure requiring dialysis occurred in a patient receiving zomepirac sodium for toothache.","label":1,"label_text":"Related"}
+{"text":"Clofibrate has been considered to be a relatively safe antidiuretic in the treatment of diabetes insipidus.","label":0,"label_text":"Not-Related"}
+{"text":"Fatal long-term immunosuppressive therapy with uncontrolled repeat prescription.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Hydroxychloroquine (HCQ) is used for treatment of lupus erythematosus.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: A 76-year-old woman with primary open-angle glaucoma and no history of ocular surgery developed a choroidal detachment 12 hours after initiation of therapy with dorzolamide eye drops.","label":1,"label_text":"Related"}
+{"text":"Indirect assessment of endogenous TRH reserve capacity was consistent with impairment of endogenous TRH activity.","label":0,"label_text":"Not-Related"}
+{"text":"Eosinophilic cystitis after bladder instillation with dimethyl sulfoxide.","label":1,"label_text":"Related"}
+{"text":"At first, these symptoms were thought to be related to the drug's antipsychotic effect.","label":0,"label_text":"Not-Related"}
+{"text":"Stool specimen was streaked with blood.","label":0,"label_text":"Not-Related"}
+{"text":"Prolonged perioperative antibiotic prophylaxis is mandatory.","label":0,"label_text":"Not-Related"}
+{"text":"Hydroxyurea is a drug widely used to control myeloproliferative disorders, due in part to its relative lack of severe side effects.","label":0,"label_text":"Not-Related"}
+{"text":"We postulate that ITB withdrawal may be a form of serotonergic syndrome that occurs from loss of gamma-aminobutyric acid B receptor-mediated presynaptic inhibition of serotonin.","label":0,"label_text":"Not-Related"}
+{"text":"Parathyroid hormone and calcitonin levels were measured along with phosphate clearance and the tubular reabsorption of phosphate.","label":0,"label_text":"Not-Related"}
+{"text":"Mammary gigantism and D-penicillamine.","label":0,"label_text":"Not-Related"}
+{"text":"Treatment consisted of supportive therapy and intravenous administration of methylene blue.","label":0,"label_text":"Not-Related"}
+{"text":"We observed intracranial hemorrhagic infarcts with focal seizures and hemiparesis associated with clotting abnormalities, including severe hypofibrinogenemia, probably the result of L-asparaginase administered during induction therapy of acute lymphocytic leukemia.","label":0,"label_text":"Not-Related"}
+{"text":"No relapse of endocarditis was observed after 12 months of follow-up.","label":0,"label_text":"Not-Related"}
+{"text":"Her liver displayed reduced volume and there was a mild accumulation of ascitic fluid in the retroperitoneal cavity.","label":0,"label_text":"Not-Related"}
+{"text":"Naloxone may be an important adjunct to therapy.","label":0,"label_text":"Not-Related"}
+{"text":"A patient experienced an organic affective psychosis on three separate occasions after taking recommended doses of non-prescription cold\/sinus preparations.","label":0,"label_text":"Not-Related"}
+{"text":"Scleroderma-like reaction induced by uracil-tegafur (UFT), a second-generation anticancer agent.","label":1,"label_text":"Related"}
+{"text":"This case is similar to four other cases described in the literature and to the neuroleptic malignant syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"We report an unusual case of development of upper eyelid depigmentation in a child 4 months following corticosteroid injection of a periocular capillary hemangioma.","label":0,"label_text":"Not-Related"}
+{"text":"Aortic transgraft hemorrhage after systemic thrombolytic therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Results are discussed in light of the existing literature.","label":0,"label_text":"Not-Related"}
+{"text":"Few reports have described dermatologic adverse effects such as rash and pruritus, and, to our knowledge, none have discussed the seriousness or extensiveness of the rash.","label":0,"label_text":"Not-Related"}
+{"text":"Of 877 patients with Crohn's disease, 484 (55. 1%) received corticosteroids during the course of the disease, 196 (22.4%) received at least one course of parenteral nutrition, and 125 (14.3%) received both corticosteroids and parenteral nutrition.","label":0,"label_text":"Not-Related"}
+{"text":"In addition, the mother drew large volumes of blood from the patient under the pretense of following a physician's orders.","label":0,"label_text":"Not-Related"}
+{"text":"Three days later, the patient returned to the emergency department with fever, vomiting, decreased energy and appetitie, and suprapubic abdominal pain, and he was hospitalized.","label":0,"label_text":"Not-Related"}
+{"text":"The results clearly demonstrate that CPH82 was associated with suppression of the endogeneous production of ACTH and cortisol with a concomitant paradoxical picture of clinical hypercortisolism.","label":1,"label_text":"Related"}
+{"text":"The potential for a variety of local and systemic side effects from the use of potent topical corticosteroids has long been recognized.","label":0,"label_text":"Not-Related"}
+{"text":"We have described three patients with hepatitis C for whom IFN-alpha and ribavirin were prescribed and who developed two successive phases of silent thyroiditis followed by hyperthryroidism relapse due to Graves' disease.","label":1,"label_text":"Related"}
+{"text":"This case report presents the clinical and radiographic course of temporomandibular joint (TMJ) involvement in a patient with severe TMJ symptoms from psoriatic arthritis (PsA) resistant to both systemic infliximab and intra-articular glucocorticoid and who therefore received multiple intra-articular infliximab injections for 36 weeks.","label":0,"label_text":"Not-Related"}
+{"text":"We describe a retrospective case series of three patients, two with bipolar depression and one with unipolar depression.","label":0,"label_text":"Not-Related"}
+{"text":"Renal biopsy three weeks after the onset of renal failure revealed evidence of focal renal cortical necrosis.","label":0,"label_text":"Not-Related"}
+{"text":"Although it is considered safe in this context, several reports of short lasting proarrythmic effects have been described.","label":0,"label_text":"Not-Related"}
+{"text":"Useful interventional thrombolytic and anticoagulant therapy for thrombosis due to embolization (TAE) in Budd-Chiari syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"In this report, we describe a patient receiving lenalidomide in whom dyspnea, fever, hypoxia, and diffuse pulmonary infiltrates developed.","label":1,"label_text":"Related"}
+{"text":"Syringotropic hypersensitivity reaction associated with infliximab and leflunomide combination therapy in a child with psoriatic arthritis.","label":1,"label_text":"Related"}
+{"text":"The catheter in the pulmonary trunk was successfully removed through a percutaneous femoral vein approach using a pigtail catheter and goose neck snare.","label":0,"label_text":"Not-Related"}
+{"text":"Therapeutic control was reestablished in both patients after therapy with the original levothyroxine product was reinstated.","label":0,"label_text":"Not-Related"}
+{"text":"The patient responded promptly to appropriate antibiotics.","label":0,"label_text":"Not-Related"}
+{"text":"One 13-year-old boy with life-threatening systemic disease experienced a partial remission of disease and tolerated a decrease in prednisone dose from 15 to 4 mg daily following 14 exchanges with FFP.","label":0,"label_text":"Not-Related"}
+{"text":"Urinalysis revealed eosinophils, and a subsequent renal biopsy confirmed a diagnosis of AIN.","label":0,"label_text":"Not-Related"}
+{"text":"A case report.","label":0,"label_text":"Not-Related"}
+{"text":"A fatal pancytopenia occurred in a patient with an history of depression with hypomanic rebounds, admitted for a manic episode and treated with levomepromazine, diazepam and lithium carbonate.","label":1,"label_text":"Related"}
+{"text":"Two workers from the same factory presented to the same emergency department within six weeks of one another with moderate (Case 1) and severe (Case 2) methemoglobinemia.","label":0,"label_text":"Not-Related"}
+{"text":"Fulminant hepatitis with severe lactate acidosis in HIV-infected patients on didanosine therapy.","label":1,"label_text":"Related"}
+{"text":"METHOD: To address the gap in knowledge, we present 2 case reports of patients with early NMS-like symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"Recovery was characterized by the gradual clearing of the pulmonary infiltrates and a gradual lessening of the severe restrictive ventilatory defects over many weeks.","label":0,"label_text":"Not-Related"}
+{"text":"So he underwent surgical treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Medical myths occur for many different reasons.","label":0,"label_text":"Not-Related"}
+{"text":"Unintentional overdose of analgesia secondary to acute dental pain.","label":0,"label_text":"Not-Related"}
+{"text":"We report two cases of severe, acute myopathy with selective degeneration of myosin filaments in asthmatics who developed respiratory failure with hypercapnia and acidosis requiring endotracheal intubation, administration of vecuronium and prolonged ventilatory support.","label":0,"label_text":"Not-Related"}
+{"text":"Choroidal detachment was diagnosed clinically and confirmed by echography.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: Progressive outer retinal necrosis is not limited to the acquired immunodeficiency syndrome but may occur in patients immunocompromised because of other conditions.","label":0,"label_text":"Not-Related"}
+{"text":"Levetiracetam may be used for maintenance antiepileptic therapy after diazepam administration.","label":0,"label_text":"Not-Related"}
+{"text":"Granulomatous reactions to permanent cosmetic tattoos successfully treated with topical steroids and allopurinol.","label":0,"label_text":"Not-Related"}
+{"text":"Oral corticotherapy combined with low-dose interferon-alpha2a halted disease progression.","label":0,"label_text":"Not-Related"}
+{"text":"The events occurred approximately 10 days after the start of each chemotherapy course.","label":0,"label_text":"Not-Related"}
+{"text":"There have been anecdotal reports of septal perforation in patients with rhinitis on intranasal corticosteroids but hitherto not in patients with ABPA.","label":0,"label_text":"Not-Related"}
+{"text":"We report a patient with chronic renal failure and ischemic heart disease who developed clinically significant methemoglobinemia after an axillary block with bupivacaine and additional injection of lidocaine in the operative field.","label":1,"label_text":"Related"}
+{"text":"Hypersensitivity reactions to cisplatin following multiple uncomplicated courses: a report on two cases.","label":1,"label_text":"Related"}
+{"text":"A new complication of cyclophosphamide, methotrexate, and 5-fluorouracil therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Controversy concerning the nephrotoxicity of lithium is discussed, and recommendations for the evaluation of renal failure during lithium therapy are provided.","label":1,"label_text":"Related"}
+{"text":"Echocardiography demonstrated a complete systolic obliteration of the left ventricular cavity.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: The central and peripheral fields were examined with the Humphrey Visual Field Analyzer.","label":0,"label_text":"Not-Related"}
+{"text":"Enzymes derived from two different bacterial sources (Escherichia coli and Erwinia carotovora) are in common use.","label":0,"label_text":"Not-Related"}
+{"text":"Transient, nonpigmenting fixed drug eruption caused by radiopaque contrast media.","label":0,"label_text":"Not-Related"}
+{"text":"A 3-year-old, 10.9-kg girl was admitted to the pediatric intensive care unit with the diagnosis of dilated cardiomyopathy and acute decompensated heart failure.","label":0,"label_text":"Not-Related"}
+{"text":"We report the successful treatment of Staphylococcus aureus endocarditis in a renal transplant recipient with preservation of his renal allograft.","label":0,"label_text":"Not-Related"}
+{"text":"Infective endocarditis was diagnosed by Duke's Criteria (Durack et al.","label":0,"label_text":"Not-Related"}
+{"text":"Biopsy of mediastinal lymphadenopathy revealed noncaseating granuloma.","label":0,"label_text":"Not-Related"}
+{"text":"Co-trimoxazole was also being administered for prophylaxis against Pneumocystis carinii infection.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: This is, to our knowledge, the first report of severe myelopathy following accidental intrathecal administration of doxorubicin.","label":1,"label_text":"Related"}
+{"text":"The possible development of a drug-induced vasculitis or lupus-like syndrome should be added to the list of rare toxic effects of vancomycin.","label":1,"label_text":"Related"}
+{"text":"This unusual cause of mental nerve neuropathy has not been previously described.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Four patients had high intraocular pressure after intravitreal ranibizumab 0.5 mg.","label":0,"label_text":"Not-Related"}
+{"text":"The etiologies of the osteonecrosis in our study included corticosteroid therapy, sickle cell disease and one case of idiopathic osteonecrosis.","label":0,"label_text":"Not-Related"}
+{"text":"The agranulocytosis was rapidly resolved by granulocyte colony-stimulating factor (G-CSF) therapy and by the discontinuation of vancomycin.","label":0,"label_text":"Not-Related"}
+{"text":"To optimize blood pressure control, the antihypertensive medication of a 76-year-old hypertensive female patient was changed from the angiotensin II receptor antagonist irbesartan to aliskiren.","label":0,"label_text":"Not-Related"}
+{"text":"When the seizures were controlled with midazolam, the hypotension subsided and norepinephrine was decreased.","label":0,"label_text":"Not-Related"}
+{"text":"Histologically, these defects appear as osteoid-like niches in the developing dentin which alter the overlying enamel.","label":0,"label_text":"Not-Related"}
+{"text":"Tardive oculogyric crisis (OGC) is a dystonic syndrome that starts after long-term use of dopamine receptor antagonists.","label":0,"label_text":"Not-Related"}
+{"text":"Clostridia are anaerobic Gram-positive bacilli that can be isolated from the soil and the intestinal tract of humans.","label":0,"label_text":"Not-Related"}
+{"text":"Clinicians have been aware of lithium toxicity for many years and traditionally have administered thiazide diuretics for lithium-induced polyuria and nephrogenic diabetes insipidus.","label":1,"label_text":"Related"}
+{"text":"One patient with systemic lupus erythematosus developed erythema multiforme after taking griseofulvin.","label":1,"label_text":"Related"}
+{"text":"Brugada syndrome (BS) is associated with sudden cardiac death in patients with a structurally normal heart.","label":0,"label_text":"Not-Related"}
+{"text":"Most patients improve after discontinuation of the drug.","label":0,"label_text":"Not-Related"}
+{"text":"Imazalil has been used to treat Alternaria infections of plant materials.","label":0,"label_text":"Not-Related"}
+{"text":"Analysis of the PCR products revealed sequences sharing close homology with the coxsackie B-like group of enteroviruses.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was then treated with sertraline without experiencing any incontinence episodes.","label":0,"label_text":"Not-Related"}
+{"text":"Central nervous system effects secondary to ciprofloxacin treatment are uncommon and usually consist only of minor dizziness or mild headache, although rare occurrences of seizures and hallucinations have been reported.","label":1,"label_text":"Related"}
+{"text":"Chronic hiccups is a rare occurrence but can be debilitating for the patient.","label":0,"label_text":"Not-Related"}
+{"text":"This patient developed severe lipoatrophy with the use of a premixed insulin containing the analogue insulin aspart.","label":0,"label_text":"Not-Related"}
+{"text":"Unfortunately, neuroleptic sensitivity in these patients limits effective pharmacological management of these symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"An Enterobacter species was cultured from an intraoperative swab.","label":0,"label_text":"Not-Related"}
+{"text":"Most interestingly, the evolution of NS paralleled the evolution of cGVHD in all patients.","label":0,"label_text":"Not-Related"}
+{"text":"Although the transthoracic echocardiography did not reveal an intra-atrial thrombus, cardioembolism due to disintegration of a pre-existing thrombus was thought to be the underlying mechanism because the patient had atrial fibrillation.","label":0,"label_text":"Not-Related"}
+{"text":"Hypothyroid goiter is a rare but well recognized complication following long term administration of iodine containing expectorants and disinfectants in children.","label":0,"label_text":"Not-Related"}
+{"text":"Neisseria sicca peritonitis in a patient maintained on chronic peritoneal dialysis.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: We report a patient who developed neutropenia on clozapine, but behind the cell count decrease showed to be a diurnal variation of the white blood cells (WBC).","label":1,"label_text":"Related"}
+{"text":"New data on lithium and haloperidol incompatibility.","label":0,"label_text":"Not-Related"}
+{"text":"A 32 year-old woman developed generalised lichenoid eruptions on her body followed by diffuse loss of scalp hair of the anagen effluvium type.","label":0,"label_text":"Not-Related"}
+{"text":"Further prospective studies should examine the patterns and prevalence of cannabis use among chronic pain populations.","label":0,"label_text":"Not-Related"}
+{"text":"Pulmonary histopathology demonstrated a mononuclear interstitial infiltrate without evidence of malignant, infectious, granulomatous, or vascular causes.","label":0,"label_text":"Not-Related"}
+{"text":"One patient reacted to glycine in the same way.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Orbital cellulitis after strabismus surgery is uncommon, may cause blindness and may lead to death.","label":0,"label_text":"Not-Related"}
+{"text":"Rituximab, a chimeric mouse\/human monoclonal antibody that binds to the CD20 antigen, is part of current treatment of many B-cell malignancies and several autoimmune diseases.","label":0,"label_text":"Not-Related"}
+{"text":"To our knowledge, this is the first case of ivermectin-induced severe liver disease published in the literature.","label":1,"label_text":"Related"}
+{"text":"A 42 year old man, treated for testicular carcinoma with combination chemotherapy that included bleomycin, developed life threatening interstitial pneumonitis.","label":1,"label_text":"Related"}
+{"text":"Scant data are available regarding the effect of hemodialysis on the elimination of argatroban.","label":0,"label_text":"Not-Related"}
+{"text":"The rash seen in this patient, who was treated with cephalexin, may be similar to the rash seen with ampicillin treatment of patients with infectious mononucleosis.","label":1,"label_text":"Related"}
+{"text":"Early dialysis in a neonate with intrauterine lisinopril exposure.","label":0,"label_text":"Not-Related"}
+{"text":"Several reports also demonstrated the efficacy of rituximab for the treatment of autoimmune cytopenia, especially for cold agglutinin disease.","label":0,"label_text":"Not-Related"}
+{"text":"It appears that a low dose of mannitol acts as a renal vasodilator while high-dose mannitol is renal vasoconstrictor.","label":0,"label_text":"Not-Related"}
+{"text":"Muscle biopsy showed nonspecific myopathic changes on light microscopy.","label":0,"label_text":"Not-Related"}
+{"text":"Acute abdomen due to endometriosis in a premenopausal woman taking tamoxifen.","label":1,"label_text":"Related"}
+{"text":"Unusual hypersensitivity to warfarin in a critically ill patient.","label":1,"label_text":"Related"}
+{"text":"Methanol poisoning continues to be a public health problem in Tunisia in spite of the different legislative measures.","label":0,"label_text":"Not-Related"}
+{"text":"Ischaemia following selfadministered intra-arterial injection of methylphenidate and diamorphine.","label":1,"label_text":"Related"}
+{"text":"Abemayor).","label":0,"label_text":"Not-Related"}
+{"text":"Eleven patients developed infection requiring hospitalization while taking leflunomide including: lower respiratory tract infections (3), cellulitis (2), disseminated herpes zoster (2), probable TB liver (1), abdominal sepsis (1), mycotic aneurysm (1) and gastroenteritis (1).","label":1,"label_text":"Related"}
+{"text":"Changes in the parameters of oxygen metabolism in a clinical course recovering from potassium cyanide.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of a patient who co-ingested a tricyclic antidepressant (2500 mg of doxepin) and a neuroleptic drug (3500 mg of prothipendyl).","label":0,"label_text":"Not-Related"}
+{"text":"Renal insufficiency was present in four patients.","label":0,"label_text":"Not-Related"}
+{"text":"In patients with swallowing dysfunction and pneumonia, a history of mineral oil use should be obtained and a diagnosis of ELP should be considered in the differential diagnoses if mineral oil use has occurred.","label":1,"label_text":"Related"}
+{"text":"Long term prognosis in these patients is better as photosensitivity gradually declines with increasing age.","label":0,"label_text":"Not-Related"}
+{"text":"One patient with ineffective erythropoiesis did not have significantly increased hepatic iron stores but responded to the administration of desferrioxamine.","label":0,"label_text":"Not-Related"}
+{"text":"A 64-year-old male with recurrent metastatic squamous cell carcinoma was successfully treated with intensive combination chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"This case draws attention to the association of long-term ergot dopamine agonist therapy with pleuropulmonary fibrosis, which can develop as late as 11 years after the initiation of therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Patients with brown recluse spider bites commonly suffer from pain, muscular aching, and a variety of local dysesthesias during the acute and resolution phases of toxin-induced injury.","label":0,"label_text":"Not-Related"}
+{"text":"The clinical activity of sirolimus in PEComa additionally strengthens the pathobiologic similarities linking PEComas to other neoplasms related to the tuberous sclerosis complex.","label":0,"label_text":"Not-Related"}
+{"text":"After 5 days of treatment with IL-2, the patient developed a hemorrhagic lesion that progressed to toxic epidermal necrolysis, as well as grade 4 pancytopenia.","label":1,"label_text":"Related"}
+{"text":"STUDY DESIGN: Case reports are presented of three premature infants (mean gestational age 27 weeks) cared for in the intensive care nursery in whom clinically significant septal hypertrophy and left ventricular outflow tract obstruction developed during dexamethasone treatment for bronchopulmonary dysplasia.","label":1,"label_text":"Related"}
+{"text":"He was treated by TACE.","label":0,"label_text":"Not-Related"}
+{"text":"The number of prior transfusions, the hepatic iron content and the serum ferritin levels appear to be useful in predicting which patients will respond to iron chelation therapy, especially if there is little bone marrow erythropoietic activity.","label":0,"label_text":"Not-Related"}
+{"text":"Skin biopsies confirmed scrofuloderma and the patient was successfully treated for tuberculosis with resolution of the brain masses.","label":0,"label_text":"Not-Related"}
+{"text":"Although he survived the acute stages following injury, his pulmonary function subsequently deteriorated with a damaged trachea and bronchi, repeated attacks of pneumonia, atelectasis, pneumothorax and lung fibrosis, leading to death with hypercapnia (PaCO2 more than 100 mmHg) after 205 days in hospital.","label":0,"label_text":"Not-Related"}
+{"text":"Pulmonary GVHD and pulmonary aspergillosis were also observed.","label":0,"label_text":"Not-Related"}
+{"text":"Ovarian endometrioid adenocarcinoma arising from an endometriotic cyst in a postmenopausal woman under tamoxifen therapy for breast cancer: a case report.","label":1,"label_text":"Related"}
+{"text":"Stanozolol causes rapid pain relief and healing of cutaneous ulcers caused by cryofibrinogenemia.","label":0,"label_text":"Not-Related"}
+{"text":"Clinical and biochemical recovery followed discontinuation of drug therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Atypical ventricular tachycardia (torsade de pointes) induced by amiodarone: arrhythmia previously induced by quinidine and disopyramide.","label":1,"label_text":"Related"}
+{"text":"Twenty-six months later, the patient is disease-free but continues to require pancreatic enzyme supplements.","label":0,"label_text":"Not-Related"}
+{"text":"Oxcarbazepine-associated angioedema manifested by swelling of the face, eyes, lips, or tongue or difficulty swallowing or breathing (or both) is a rare but potentially life-threatening reaction for which early recognition and management are vital.","label":1,"label_text":"Related"}
+{"text":"We also review the literature on similar cases and on the safety of ECT with muscle relaxation in this condition.","label":0,"label_text":"Not-Related"}
+{"text":"There were small changes in the shape of the P waves and P-R intervals.","label":0,"label_text":"Not-Related"}
+{"text":"Triiodothyronine-induced thyrotoxicosis in ophthalmic Graves disease.","label":1,"label_text":"Related"}
+{"text":"Although an increased incidence of Mycobacterium tuberculosis infection is found in patients after subtotal gastrectomy, to my knowledge, the potential for gastrectomy to alter the course and outcome of typical mycobacterial disease has not been noted.","label":0,"label_text":"Not-Related"}
+{"text":"However, reticulocytes were markedly increased in number on the 13th day of hospitalization.","label":0,"label_text":"Not-Related"}
+{"text":"We propose that hypersexuality on antiparkinsonian drugs is consequent to inhibition of prolactin secretion.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of a patient with the acquired immunodeficiency syndrome treated with rifampicin who had a 'normal' screening test for adrenal insufficiency, yet had clinical evidence of adrenal failure.","label":1,"label_text":"Related"}
+{"text":"She received induction therapy according to the AML92 protocol of the Japan Adult Leukemia Study Group (JALSG) with all-trans retinoic acid (ATRA) plus chemotherapeutic agents.","label":0,"label_text":"Not-Related"}
+{"text":"The currently available clinical and neuropharmacologic data suggest that carbamazepine may be an antagonist of dopamine and that this property is responsible for the production of dystonia.","label":1,"label_text":"Related"}
+{"text":"A thyroid scan performed at that time revealed a gland of normal size and texture.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: We describe atypical motor and cognitive features in a case of familial Alzheimer disease (FAD) due to presenilin-1 (PS-1) mutation.","label":0,"label_text":"Not-Related"}
+{"text":"Fluorinated topical steroids have been implicated as the cause or precipitating factor in previous case reports mainly involving an adult population.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: Patients successfully treated with maintenance doses of im gold (< 20 mg\/mo and not more than 10 mg\/dose) were identified by chart review.","label":0,"label_text":"Not-Related"}
+{"text":"Hypothyroid and hyperthyroid disease are both associated with a variety of muscle abnormalities, from myalgias to myopathy.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND AND OBJECTIVES: Sternal fracture pain is severe and is difficult to alleviate due to the forces acting on the chest wall during respiration.","label":0,"label_text":"Not-Related"}
+{"text":"Careful assessment of all VADs is important to identify complications such as fibrin sheath formation, which can potentially lead to extravasation.","label":0,"label_text":"Not-Related"}
+{"text":"Other potentially related factors included electrolyte abnormalities and prior neurological insult.","label":0,"label_text":"Not-Related"}
+{"text":"A patient is described with polycythemia vera who was taking anticoagulants and developed a spontaneous retropharyngeal hemorrhage after a violent sneezing episode.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of a patient who developed reactivation Histoplasmosis after receiving anti-TNF-alpha.","label":0,"label_text":"Not-Related"}
+{"text":"Hemolytic uremic syndrome in a patient on cis-platinum, vinblastine and bleomycin.","label":1,"label_text":"Related"}
+{"text":"Autopsy evidence of herpesvirus infection was found in visceral organs of four leukemic patients who had received large doses of cytarabine (cytosine arabinoside; Ara-C) shortly before their death.","label":1,"label_text":"Related"}
+{"text":"The presentation PTLD is diverse, including many patients with symptoms of the head and neck, which may make diagnosis difficult.","label":0,"label_text":"Not-Related"}
+{"text":"Quadriplegia due to lead-contaminated opium--case report.","label":0,"label_text":"Not-Related"}
+{"text":"Of the 3 methods of treatment used, the pars plana anterior vitrectomy approach seemed the most effective and the medical approach with 4% cocaine seemed to be the least predictable.","label":0,"label_text":"Not-Related"}
+{"text":"Ultrastructural study of a renal biopsy in each case showed extensive glomerular epithelial cell foot process fusion.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: Concentrated epinephrine has the potential for complications when used during endoscopic sinus surgery.","label":0,"label_text":"Not-Related"}
+{"text":"We reported a child with refractory partial seizures successfully managed by clinical desensitization to phenytoin.","label":0,"label_text":"Not-Related"}
+{"text":"CMV antigenemia became negative within 2 weeks and never developed again.","label":0,"label_text":"Not-Related"}
+{"text":"The diagnosis may be made more difficult due to lack of typical allergic symptoms, presence of other drugs, or confounding factors and equivocal noninvasive laboratory studies.","label":0,"label_text":"Not-Related"}
+{"text":"Listeria brain abscess, Pneumocystis pneumonia and Kaposi's sarcoma after temozolomide.","label":1,"label_text":"Related"}
+{"text":"CASE REPORT: A 27-year-old male presented a corticosteroid-resistant nephrotic syndrome secondary to collapsing FGS corticosteroid.","label":0,"label_text":"Not-Related"}
+{"text":"A 56-year-old male parkinsonian patient developed a unique behavioral change following the oral administration of cinepazide, a cerebral vasodilator.","label":1,"label_text":"Related"}
+{"text":"The replies indicate that, at least from the patient's viewpoint, this syndrome occurs frequently.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To report 2 cases of serotonin syndrome with serious extrapyramidal movement disorders occurring when metoclopramide was coadministered with sertraline or venlafaxine.","label":1,"label_text":"Related"}
+{"text":"The literature on thiabendazole-induced cholestasis and its association with sicca complex is reviewed.","label":1,"label_text":"Related"}
+{"text":"Review of all reported cases of the use of ATRA in pregnancy revealed no serious adverse outcomes or congenital anomalies although only very few cases had exposure in the first trimester.","label":0,"label_text":"Not-Related"}
+{"text":"Known side-effects of salbutamol are described.","label":0,"label_text":"Not-Related"}
+{"text":"Laboratory evaluation revealed a very low serum cortisol level with a concomitantly low-normal level of adrenocorticotropic hormone (corticotropin).","label":0,"label_text":"Not-Related"}
+{"text":"This case demonstrates that although percutaneous retrogasserian phenol injection is a relatively safe and noninvasive method of treatment for trigeminal neuralgia, severe complications may occur.","label":0,"label_text":"Not-Related"}
+{"text":"Severe systemic cytomegalovirus infections in patients with steroid-refractory ulcerative colitis treated by an oral microemulsion form of cyclosporine: report of two cases.","label":0,"label_text":"Not-Related"}
+{"text":"Two children with leukemia developed PTE, the first during the relapse for acute lymphoblastic leukemia and the second at the onset of acute promyelocytic leukemia.","label":0,"label_text":"Not-Related"}
+{"text":"Post radiation sarcoma (malignant fibrous histiocytoma) of the cervical spine following ependymoma (a case report).","label":0,"label_text":"Not-Related"}
+{"text":"After one course of Campath-1H his hematologic parameters normalized, suggesting that the compound may be an effective therapy for complex immunohematologic disorders complicating hematopoietic stem cell transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"Doxorubicin, bleomycin, dacarbazine, and prophylactic pegfilgrastim (a granulocyte colony-stimulating factor), were administered.","label":0,"label_text":"Not-Related"}
+{"text":"Nocardia brain abscess is a rare condition, seen most commonly among immunocompromised patients.","label":0,"label_text":"Not-Related"}
+{"text":"Hemolytic uremic syndrome in a patient on cis-platinum, vinblastine and bleomycin.","label":1,"label_text":"Related"}
+{"text":"On the 6th day of chemotherapy, she was in a drowsy state following generalized tonic clonic seizure lasting 20 minutes.","label":0,"label_text":"Not-Related"}
+{"text":"While fluoroscopy is a reliable method for identifying boney structures, ultrasound may identify the vertebral vessels, thyroid gland and vessels, longus coli muscles, nerve roots and the esophagus.","label":0,"label_text":"Not-Related"}
+{"text":"A spinal-cord injury can alter every aspect of a victim's life.","label":0,"label_text":"Not-Related"}
+{"text":"L-asparaginase-provoked seizures as singular expression of central nervous toxicity.","label":1,"label_text":"Related"}
+{"text":"Reversal reactions are caused immunologically by enhanced cell-mediated (Th-1) immunity to Mycobacterium leprae, resulting in inflammation of infected tissues, such as skin and nerves.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients received 6 mg sumatriptan subcutaneously on days 4 and 6, and one patient 3 x 100 mg sumatriptan orally on day 1 after an acute headache episode.","label":0,"label_text":"Not-Related"}
+{"text":"His obstruction resolved, and he remains well at 11 months.","label":0,"label_text":"Not-Related"}
+{"text":"Tamoxifen has been used as a chemotherapeutic agent with no serious side effects noted.","label":0,"label_text":"Not-Related"}
+{"text":"We report the case of a 60-year-old woman who developed erythema and erosions in the axilla and groin while on PLD for breast cancer.","label":1,"label_text":"Related"}
+{"text":"At his last visit, 12 months later, his vision had improved and his serum creatinine was lower, at 2.2 mg\/dL.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Over the past decade, the treatment of Parkinson disease (PD) has undergone tremendous changes.","label":0,"label_text":"Not-Related"}
+{"text":"This article describes the case of a 25-year-old man found dead at home who had been prescribed olanzapine for schizophrenia.","label":1,"label_text":"Related"}
+{"text":"In conclusion, we were confronted with an unusual case of pheochromocytoma associated with renal artery stenosis and the appearance of watery diarrhea some days after surgical treatment.","label":0,"label_text":"Not-Related"}
+{"text":"High doses of atropine (up to 50 mg per 24 hours), adrenaline and dopamine were necessary.","label":0,"label_text":"Not-Related"}
+{"text":"The pulses consisted of four repeated doses of 500 mg of hydrocortisone given intravenously over 20 to 30 minutes at six-hour intervals or of single intravenous injections of 30 mg\/kg of methylprednisolone.","label":0,"label_text":"Not-Related"}
+{"text":"Retinal dysfunction and anterior segment deposits in a patient treated with rifabutin.","label":1,"label_text":"Related"}
+{"text":"In patient 4, it occurred several hours after the first ranibizumab injection.","label":0,"label_text":"Not-Related"}
+{"text":"Close examination revealed a cauda equina tumor at the level of L2 and L3.","label":0,"label_text":"Not-Related"}
+{"text":"After treatment, the arterial blood pH rose to 7.53, and vasopressor agents were no longer needed to support blood pressure.","label":0,"label_text":"Not-Related"}
+{"text":"Judging from the patient's course under treatment specific for M. malmoense, the gastrointestinal symptoms were rather manifestations of a chronic relapsing mycobacterial infection.","label":0,"label_text":"Not-Related"}
+{"text":"Patients receiving amifostine who develop only fever should be evaluated for an adverse drug reaction, as well as for sepsis and fevers of neutropenia, and it may be necessary to discontinue the drug.","label":1,"label_text":"Related"}
+{"text":"Falling backward in two elderly patients taking bupropion.","label":1,"label_text":"Related"}
+{"text":"We describe six patients who developed tardive dyskinesia after treatment with sulpiride for depression or gastrointestinal symptoms.","label":1,"label_text":"Related"}
+{"text":"DIAGNOSIS: Severe temozolomide-induced immunosuppression, exacerbated by corticosteroids, with profound T-cell lymphocytopenia and simultaneous opportunistic infections with Pneumocystis jiroveci pneumonia, brain abscess with Listeria monocytogenes, and cutaneous Kaposi's sarcoma.","label":1,"label_text":"Related"}
+{"text":"Vancomycin (14 mg\/mL) was also given twice daily in 2 patients.","label":0,"label_text":"Not-Related"}
+{"text":"The assay had a limit of detection of 0.05 mg\/L and an upper limit of linearity of 2 mg\/L.","label":0,"label_text":"Not-Related"}
+{"text":"We reported a demonstration case of a 47 year-old female patient with hypersensitivity to anti tuberculosis drugs (isoniazid, rifampicin, pyrazinamid and ethambutol).","label":0,"label_text":"Not-Related"}
+{"text":"Optimizing antithrombotic therapy in patients with non-ST-segment elevation acute coronary syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Against the advice of her oncologist, she abandoned traditional therapy and started an alternative regimen that included cesium chloride supplements.","label":0,"label_text":"Not-Related"}
+{"text":"Both the skin lesions and the enteropathy respond to gluten restriction.","label":0,"label_text":"Not-Related"}
+{"text":"Cefuroxime-induced acute renal failure.","label":1,"label_text":"Related"}
+{"text":"The authors describe a patient who had a secondary liver infarct during anticoagulant treatment for cerebral infarction.","label":0,"label_text":"Not-Related"}
+{"text":"However, there may be a publication bias in some case reports and studies towards reporting successful rather than unsuccessful CPRs.","label":0,"label_text":"Not-Related"}
+{"text":"Loperamide poisoning in the dog.","label":1,"label_text":"Related"}
+{"text":"The neonatal lamotrigine elimination half-life was approximately twice that seen in adults.","label":0,"label_text":"Not-Related"}
+{"text":"These case reports highlight the potential for anti-CTLA-4-based therapy in previously treated patients with advanced melanoma.","label":0,"label_text":"Not-Related"}
+{"text":"A complete remission was achieved in 96% of children in relapse and in five out of six children resistant to induction.","label":0,"label_text":"Not-Related"}
+{"text":"BACKGROUND: Metformin has been shown to reduce complications and mortality from Type 2 diabetes mellitus, and is increasingly used to treat this condition.","label":0,"label_text":"Not-Related"}
+{"text":"UI resolved after discontinuation of the drug and did not reappear after switching to sertraline therapy.","label":0,"label_text":"Not-Related"}
+{"text":"All 3 patients experienced fairly typical chest pain syndromes and experienced elevations of cardiac enzymes consistent with myocardial ischemia.","label":0,"label_text":"Not-Related"}
+{"text":"Three male patients aged 78-83 years are presented, in whom severe hepatotoxic reactions emerged after CPA administration.","label":1,"label_text":"Related"}
+{"text":"The prognostic significance of this pattern in drug overdose is therefore not definitive by itself.","label":0,"label_text":"Not-Related"}
+{"text":"METHOD: Case analysis of a poly-drug overdose (venlafaxine, topiramate, divalproex sodium, risperidone, and carbamazepine) presenting with mixed SS\/NMS features and whose clinical management suggests a practical algorithm for treatment of undifferentiated SS\/NMS in critical care settings.","label":1,"label_text":"Related"}
+{"text":"This reports presents two cases of hypercontractile heart failure during beta-agonist treatment in very low birthweight (VLBW) infants.","label":0,"label_text":"Not-Related"}
+{"text":"Then, they quickly decreased to 35 and 75% on the 10th day, and 6 months later, they became 16 and <3% of the control, respectively.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: In some abstainers who take cyanamide for several years, thin septum-like liver fibrosis progresses along with the emergence of ground-glass hepatocytes.","label":1,"label_text":"Related"}
+{"text":"A patient is described with the characteristic features of phenytoin hypersensitivity syndrome (PHS) including fever, erythroderma, tibial and facial oedema, pinhead-sized facial pustules and abnormal liver function tests.","label":1,"label_text":"Related"}
+{"text":"Oral effects of steroid therapy in a patient with systemic lupus erythematosus: report of case.","label":0,"label_text":"Not-Related"}
+{"text":"This neurocutaneous syndrome consists of angiomatosis of the skin and mucosa as well as the leptomeninges.","label":0,"label_text":"Not-Related"}
+{"text":"Acute GVHD developed at the end of therapy and the patient's leukemia went into remission.","label":0,"label_text":"Not-Related"}
+{"text":"The risk for recurrence in a subsequent pregnancy may be high and should be taken into account in the counseling of parents and in considering drug treatment.","label":0,"label_text":"Not-Related"}
+{"text":"This represents a significant improvement over normal body clearance (4.7 ml\/min\/kg) in pediatric patients.","label":0,"label_text":"Not-Related"}
+{"text":"In three of these patients the infection was clinically unsuspected; in the fourth, cutaneous herpes zoster developed after administration of 300 mg of cytarabine daily for the preceding five days.","label":1,"label_text":"Related"}
+{"text":"A case is presented which illustrates a probably fatal interaction between minoxidil and a coagulation disorder.","label":1,"label_text":"Related"}
+{"text":"The first patient displayed symptoms resembling those of organic brain syndrome which was not associated with a high serum lithium level.","label":0,"label_text":"Not-Related"}
+{"text":"An infection had spread up the right leg, after she had been swimming on holiday in the Canary Islands.","label":0,"label_text":"Not-Related"}
+{"text":"Large infarct size and initiation of anticoagulation after early (less than 12 hours) computed tomography were associated with hemorrhagic transformation and clinical worsening in patients who received anticoagulation therapy.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: The intravitreal ganciclovir implant provides safe and effective therapy against CMV retinitis, and should be considered in patients acquiring the infection after stem cell transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"She received several vasoactive infusions during her admission, including nesiritide.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: Recent data suggest that eosinophils may directly damage the gastrointestinal tract wall in eosinophilic gastroenteritis.","label":0,"label_text":"Not-Related"}
+{"text":"Cephalosporin-induced leukopenia following rechallenge with cefoxitin.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: the allergological studies confirmed sensitisation to captopril and tolerance to lisinopril, and enalapril.","label":0,"label_text":"Not-Related"}
+{"text":"Regression of thyrotoxic ophthalmopathy following lithium withdrawal.","label":1,"label_text":"Related"}
+{"text":"A biopsy of the deltoid muscle showed vacuolar degeneration of striated muscle fibers with no inflammatory findings.","label":0,"label_text":"Not-Related"}
+{"text":"Dose deflation of psychotropics was feasible in 35 subjects (74.5%).","label":0,"label_text":"Not-Related"}
+{"text":"The pulmonary toxicity of gold salts is an uncommon cause of life-threatening respiratory failure.","label":1,"label_text":"Related"}
+{"text":"Buphthalmos following systemic steroid treatment.","label":0,"label_text":"Not-Related"}
+{"text":"In none of the patients were any definite clinical, laboratory or morphological signs of an approaching leukaemic transformation of the polycythaemic disorder present.","label":0,"label_text":"Not-Related"}
+{"text":"In two patients with mycosis fungoides, a squamous cell carcinoma developed during therapy with psoralens plus long-wave ultraviolet radiation (PUVA).","label":1,"label_text":"Related"}
+{"text":"Drug provocation test is still a gold standard to establish the diagnosis of hypersensitivity to certain drugs or agents.","label":0,"label_text":"Not-Related"}
+{"text":"A possible tumor necrosis factor-alpha-mediated dedifferentiation of adipocytes.","label":0,"label_text":"Not-Related"}
+{"text":"These cases highlight the importance of considering PTLD in the differential diagnosis of lymphadenopathy and fever post ASCT.","label":0,"label_text":"Not-Related"}
+{"text":"He was started on oral lansoprazole 60 mg twice daily and, on hospital day 2, his platelet count decreased to 102 x 10(3)\/mm(3); on hospital day 3, the platelet count was 36 x 10(3)\/mm(3).","label":1,"label_text":"Related"}
+{"text":"OBJECTIVE: To describe a case of exacerbated mania potentially related to an interaction between lopinavir\/ritonavir and valproic acid (VPA) and propose a mechanism of action for this interaction.","label":1,"label_text":"Related"}
+{"text":"In addition, three of the four patients had unusual corneal changes.","label":0,"label_text":"Not-Related"}
+{"text":"Dopamine agonists (DA) have been associated with pathological gambling (PG) and other compulsive behaviors in Parkinson's disease (PD).","label":0,"label_text":"Not-Related"}
+{"text":"This study examines if gadolinium can be removed by frequent exchanges by peritoneal dialysis (PD).","label":0,"label_text":"Not-Related"}
+{"text":"The occurrence of BMTN in two children treated with RA in our unit is unlikely to be coincidental.","label":1,"label_text":"Related"}
+{"text":"Caused by the increasing spreading of angel's trumpet shrubberies in Europe and North America, intoxications with large numbers of fatalities have to be expected in the future.","label":0,"label_text":"Not-Related"}
+{"text":"Acute renal failure (ARF) is an uncommon complication in children with nephrotic syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Acute spontaneous TLS is rare, and it has been described in leukemia and lymphoma and in some patients with solid tumors prior to institution of therapy.","label":0,"label_text":"Not-Related"}
+{"text":"In three cases, there was a close temporal correlation between the use of a corticosteroid nasal spray and the development of CSC.","label":0,"label_text":"Not-Related"}
+{"text":"Acute coronary events following cisplatin-based chemotherapy.","label":1,"label_text":"Related"}
+{"text":"CONCLUSION: Linezolid seems highly active in combination treatment of MDR-TB.","label":0,"label_text":"Not-Related"}
+{"text":"It is well-recognized that flucloxacillin may occasionally result in fatal hepatic injury.","label":1,"label_text":"Related"}
+{"text":"Pigmentary disorders are recognized adverse effects of the semi-synthetic tetracycline derivative antibiotic, minocycline.","label":1,"label_text":"Related"}
+{"text":"In the immunocompetent host, antiviral therapy can successfully treat herpesvirus respiratory infection, with reversal of clinical, virologic, and pathologic findings.","label":0,"label_text":"Not-Related"}
+{"text":"The number of lymphocytes in his peripheral blood, and titres of serum total IgG and IgM and anti-desmoglein1 antibody transiently decreased just before reactivation of HHV-6, cytomegalovirus and Epstein-Barr virus.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS AND RESULTS: This report describes a Merkel cell carcinoma which developed in a liver transplant recipient.","label":0,"label_text":"Not-Related"}
+{"text":"This case illustrates an unusual adverse effect of clonidine.","label":0,"label_text":"Not-Related"}
+{"text":"Little experience exists with this drug in the pediatric population, however.","label":0,"label_text":"Not-Related"}
+{"text":"A dapsone hypersensitivity syndrome, consisting of fever, headache, nausea, vomiting, lymphadenopathy, hepatitis, hemolysis, leukopenia, and mononucleosis, has been described in patients treated with the drug for leprosy.","label":1,"label_text":"Related"}
+{"text":"An unrelated allogeneic stem cell transplantation was performed.","label":0,"label_text":"Not-Related"}
+{"text":"Other pertinent laboratory data, including liver and renal function tests results, serology for virus infection, and serum levels of vitamin B12 and folic acids, were normal.","label":0,"label_text":"Not-Related"}
+{"text":"These case reports provide evidence that 5-aminosalicylic acid may induce acute pancreatitis after long term treatment.","label":1,"label_text":"Related"}
+{"text":"We present a case of acute epinephrine toxicity resulting in acute myocardial ischemia in a young boy with combined variable immunodeficiency syndrome who developed severe allergic reaction to intravenous immunoglobulin, and was subsequently given epinephrine by mistake intravenously rather than subcutaneously.","label":1,"label_text":"Related"}
+{"text":"Alone or in combination with corticosteroids, cyclosporine is an effective drug of choice for the resistant patients.","label":0,"label_text":"Not-Related"}
+{"text":"We started the subject screening from over 400 patients with Parkinson's disease using strict selection criteria to identify the patients with nocturia who would allow accurate and efficient evaluation of the pergolide effects.","label":0,"label_text":"Not-Related"}
+{"text":"Fatal gemcitabine-induced pulmonary toxicity in metastatic   gallbladder adenocarcinoma.","label":1,"label_text":"Related"}
+{"text":"This case demonstrated the importance of obtaining complete drug histories from patients.","label":0,"label_text":"Not-Related"}
+{"text":"Color Doppler was used to demonstrate a high flow pattern that, unlike in the adult goiter, was associated with hypothyroidism in the neonate.","label":0,"label_text":"Not-Related"}
+{"text":"Recurrent bacteremia developed necessitating Hickman line removal for eventual resolution of the infection.","label":0,"label_text":"Not-Related"}
+{"text":"Due to chloroquine resistance, several African countries have changed their first-line malaria treatment to sulfadoxine-pyrimethamine (SP).","label":0,"label_text":"Not-Related"}
+{"text":"Infection and inflammation in patients on dialysis: an underlying contributor to anemia and epoetin alfa hyporesponse.","label":0,"label_text":"Not-Related"}
+{"text":"Cessation of topiramate caused return of episodes, and the response has persisted for 2 years.","label":0,"label_text":"Not-Related"}
+{"text":"METHOD: A 59-year-old, right-handed man of Caribbean-Hispanic descent underwent brain imaging studies, laboratory tests for AD, and serial neurologic and neuropsychologic evaluations.","label":0,"label_text":"Not-Related"}
+{"text":"Toxic epidermal necrolysis (TEN), or Lyell's syndrome, is a fulminant bullous dermatitis.","label":0,"label_text":"Not-Related"}
+{"text":"A second renal biopsy was performed, which confirmed the diagnosis of acute interstitial nephritis.","label":0,"label_text":"Not-Related"}
+{"text":"A 27-year-old man who had a history of bronchial asthma, eosinophilic enteritis, and eosinophilic pneumonia presented with fever, skin eruptions, cervical lymphadenopathy, hepatosplenomegaly, atypical lymphocytosis, and eosinophilia two weeks after receiving trimethoprim (TMP)-sulfamethoxazole (SMX) treatment.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: These results suggest that clozapine may cause TD; however, the prevalence is low and the severity is relatively mild, with no or mild self-reported discomfort.","label":1,"label_text":"Related"}
+{"text":"Prior neurologic illness or CNS insult of any kind is known to increase the vulnerability to neurotoxicity of lithium.","label":1,"label_text":"Related"}
+{"text":"The most common complication of warfarin use is adverse bleeding.","label":1,"label_text":"Related"}
+{"text":"Ultrasound examination confirmed the diagnosis and subsequent resolution of the thrombus.","label":0,"label_text":"Not-Related"}
+{"text":"Many of such strokes are asymptomatic, but some are devastating.","label":0,"label_text":"Not-Related"}
+{"text":"The direct antiglobulin test (DAT) was negative at diagnosis but was found to be positive with anti-IgG after the first fludarabine treatment.","label":0,"label_text":"Not-Related"}
+{"text":"Other corticosteroids of group A, B, C and D were completely negative.","label":0,"label_text":"Not-Related"}
+{"text":"Severe serotonin syndrome induced by mirtazapine monotherapy.","label":1,"label_text":"Related"}
+{"text":"Moreover, young women given vitamin A and tetracycline in combination for acne may be at special risk and should be kept under surveillance.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Acute severe hepatitis though rare is occasionally observed with EGFR inhibitors gefitinib or erlotinib.","label":1,"label_text":"Related"}
+{"text":"Here we present the case of a woman who received high doses of methylprednisolone (1 g iv daily) for active Graves' ophthalmopathy, and developed severe hypertension followed by myocardial infarction on the fifth day of treatment.","label":1,"label_text":"Related"}
+{"text":"Due to refractory elevations of ICP, high-dose pentobarbital infusion was initiated, and ICP gradually normalised.","label":0,"label_text":"Not-Related"}
+{"text":"The target antigen, cause of the positive direct antiglobulin test (DAT) and mechanism of hemolysis have been the subject of controversy.","label":0,"label_text":"Not-Related"}
+{"text":"Although, we cannot exclude the coincidence between the two diseases we discussed suspicious relationship between the interferon treatment and the tumour progression.","label":0,"label_text":"Not-Related"}
+{"text":"Data on efficacy of late administration of oximes, particularly obidoxime, is limited.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: The new quinolone derivatives (levofloxacin, sparfloxacin, grepafloxacin, trovafloxacin, gatifloxacin and moxifloxacin), also called gyrase inhibitors, are known for their potential to cause central nervous system-related adverse effects, including headache, dizziness and insomnia.","label":1,"label_text":"Related"}
+{"text":"The patient was heterozygous for the factor V Leiden mutation.","label":0,"label_text":"Not-Related"}
+{"text":"We hypothesize that decreased renal elimination of MTX induced by the COX-2 inhibitor resulted in enhanced hematopoietic toxicity and immunosuppression causing the EBV-associated lymphoproliferative disease.","label":1,"label_text":"Related"}
+{"text":"We report the case of a 54-year old man with decompensated alcoholic liver cirrhosis and HIV infection who underwent liver transplantation (LT).","label":0,"label_text":"Not-Related"}
+{"text":"This report documents the occurrence of severe glomerular pathology associated with continuous, daily antituberculous therapy.","label":0,"label_text":"Not-Related"}
+{"text":"Clinicians should monitor patients receiving this drug for signs of LABD.","label":0,"label_text":"Not-Related"}
+{"text":"Therefore, calcium-channel blockers should be used carefully in peculiar cases of HOCM.","label":0,"label_text":"Not-Related"}
+{"text":"The only positive finding was enlargement of the abdomen without tenderness.","label":0,"label_text":"Not-Related"}
+{"text":"These antiplatelet agents were continued during the perioperative period.","label":0,"label_text":"Not-Related"}
+{"text":"Only 1 death occurred, and most patients (57.5%) had complete resolution of their symptoms within 24 hours of presentation.","label":0,"label_text":"Not-Related"}
+{"text":"Intravitreal antivascular endothelial growth factor (VEGF) drugs are presently being used to treat DME.","label":0,"label_text":"Not-Related"}
+{"text":"This effect was noted to persist throughout the 15-month observation period with no breakthrough dyskinesia.","label":0,"label_text":"Not-Related"}
+{"text":"In the literature, PNH cases also showed neutropenia (0 and 0.54 x 10(9)\/l) at aplastic crises.","label":0,"label_text":"Not-Related"}
+{"text":"The diagnosis of ELP was made.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: We report the case of a 20-year-old male patient with septo-optic dysplasia, fixed cranial diabetes insipidus (DI) and an abnormal thirst threshold.","label":0,"label_text":"Not-Related"}
+{"text":"Immunoprecipitation and Western blot analysis were then used to demonstrate that the aberrant DPD mRNA is translated into a nonfunctional DPD protein that is ubiquitinated.","label":0,"label_text":"Not-Related"}
+{"text":"However, the chlorpromazine equivalent dose of antipsychotics and the number of total psychotropics were significantly reduced from 957 to 722 mg\/day (p<0.0001) and from 4.0 to 3.2 (p<0.0001), respectively.","label":0,"label_text":"Not-Related"}
+{"text":"This article describes two cases of aplastic anemia, at least one of which was almost certainly induced by the use of methazolamide, and one case of agranulocytosis related to the use of methazolamide.","label":1,"label_text":"Related"}
+{"text":"She was diagnosed with Epstein-Barr virus-associated polymorphic lymphoproliferative disorder (LPD) due to immunodeficiency caused by MTX administration.","label":1,"label_text":"Related"}
+{"text":"The patient remained constantly HIV negative during 14 months of follow-up.","label":0,"label_text":"Not-Related"}
+{"text":"The infection ultimately cleared in all eyes with topical therapy using chlorhexidine, propamidine, and antibiotic ointment with neomycin.","label":0,"label_text":"Not-Related"}
+{"text":"We report a 43-year-old woman who developed sore throat, swelling of the lips and oral cavity and dysphagia, 2 weeks after the use of budesonide spray (Budefat) for treatment of bronchial asthma.","label":1,"label_text":"Related"}
+{"text":"A case report of a three kilogram, four month infant who received excessive doses of chloramphenicol for the treatment of bacterial meningitis is presented.","label":0,"label_text":"Not-Related"}
+{"text":"Inflammation may be a component of TiACG.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: Despite extremely delayed presentation, aggressive CDT was successful in both breast, and head and neck reconstructions with excellent long-term flap results.","label":0,"label_text":"Not-Related"}
+{"text":"This case report describes an adolescent with severe lupus erythematosus who received cyclophosphamide (CY) paired with taste (cod liver oil) and smell (rose perfume) as conditioned stimuli.","label":1,"label_text":"Related"}
+{"text":"Case report.","label":0,"label_text":"Not-Related"}
+{"text":"Effect of o,p'-DDD on serum and urinary androgens.","label":0,"label_text":"Not-Related"}
+{"text":"The QT interval must be measured on the ECG in patients with unexplained seizures; \"supraventricular tachycardia with aberration\" is uncommon in children.","label":0,"label_text":"Not-Related"}
+{"text":"Thrombolytic treatment is advocated for critical patients unless emergency institution of cardio pulmonary bypass is required and\/or indicated.","label":0,"label_text":"Not-Related"}
+{"text":"Hypokalemia after normal doses of neubulized albuterol (salbutamol).","label":1,"label_text":"Related"}
+{"text":"2-CdA typically causes a long-lasting state of immunodeficiency and the profound influence of this drug on the immune system has raised questions concerning the emergence of secondary neoplasms after its use.","label":1,"label_text":"Related"}
+{"text":"Urethral syndrome: response to alpha-adrenergic blocking agents.","label":0,"label_text":"Not-Related"}
+{"text":"He was started on digoxin, 0.25 mg daily, because of echocardiographically demonstrated left ventricular dilatation and functional impairment; he died of ventricular fibrillation 15 days later.","label":1,"label_text":"Related"}
+{"text":"MK-0457 (VX-680) is a small-molecule aurora kinase (AK) inhibitor with preclinical antileukemia activity.","label":0,"label_text":"Not-Related"}
+{"text":"Three patients who received more than 1100 mg\/m2 developed pulmonary symptoms with the same clinical and radiologic pattern as in the two cases with pathologic documents, and two of them died from acute respiratory failure.","label":0,"label_text":"Not-Related"}
+{"text":"The possible mechanisms by which iodine-containing drugs induce thyroid disfunction are reviewed, suggesting this case was caused by an alteration in the sensitivity of the intrinsic autoregulation of the thyroid gland to iodine.","label":0,"label_text":"Not-Related"}
+{"text":"Disseminated intravascular coagulation associated with acute hemoglobinemia or hemoglobinuria following Rh(0)(D) immune globulin intravenous administration for immune thrombocytopenic purpura.","label":1,"label_text":"Related"}
+{"text":"Dexamethasone levels were measured in the serum by radioimmunoassay and shown to be lowered by o,p'-DDD therapy.","label":0,"label_text":"Not-Related"}
+{"text":"We report a case of Ritalin-associated cataract and glaucoma.","label":1,"label_text":"Related"}
+{"text":"Appropriate methods for sterilizing endoscopes are reviewed, including sterilization with 2.5 per cent glutaraldehyde solution and ethylene oxide gas.","label":0,"label_text":"Not-Related"}
+{"text":"The gold standard for diagnosis is renal biopsy, but it is only rarely performed during the acute phase of the reaction and is not without risk.","label":0,"label_text":"Not-Related"}
+{"text":"Her plasma cesium level was 2400 microg\/dl (normal < 1 microg\/dl), and her family was told to stop her alternative treatment regimen.","label":0,"label_text":"Not-Related"}
+{"text":"The presence of thrombi in this early-stage lesion suggests that thrombosis plays a role in the initial pathogenesis of this condition.","label":0,"label_text":"Not-Related"}
+{"text":"In order to induce further resorption of the haematoma.","label":0,"label_text":"Not-Related"}
+{"text":"A patient with post-traumatic epilepsy who had remained fit-free for many years until she was given the 5-HT reuptake inhibitor fluvoxamine is reported.","label":0,"label_text":"Not-Related"}
+{"text":"An 88-year-old woman developed necrotizing scleritis after eye muscle surgery.","label":0,"label_text":"Not-Related"}
+{"text":"Because she could not tolerate ketoconazole and was hypersensitive to griseofulvin, she received itraconazole with complete recovery within 30 days.","label":0,"label_text":"Not-Related"}
+{"text":"The literature pertaining to sex hormones and their role in affecting periodontal disease is reviewed.","label":0,"label_text":"Not-Related"}
+{"text":"An electroencephalogram was consistent with the diagnosis of nonconvulsive status epilepticus.","label":0,"label_text":"Not-Related"}
+{"text":"The ACAD is defined as a diffuse process affecting the entire length of epicardial vessels.","label":0,"label_text":"Not-Related"}
+{"text":"To date, reports about the macroscopic appearance of ventriculitis have been rare, consisting only of a few autopsy cases.","label":0,"label_text":"Not-Related"}
+{"text":"It is widely used in rheumatologic diseases, and has a very high efficacy\/toxicity ratio.","label":0,"label_text":"Not-Related"}
+{"text":"Extensive osseous tophi, resorbed rapidly during therapy with this xanthine oxidase inhibitor and not replaced by new bone matrix, were responsible for the deformity.","label":0,"label_text":"Not-Related"}
+{"text":"We recommend that the immune status of these patients to varicella-zoster virus be assessed by a serum titer.","label":0,"label_text":"Not-Related"}
+{"text":"The authors report a further case of methimazole-associated liver damage and present a brief review of eleven previous cases found in the literature.","label":1,"label_text":"Related"}
+{"text":"The drug was discontinued, his symptoms resolved, and his liver function tests returned to normal.","label":0,"label_text":"Not-Related"}
+{"text":"Overall, responses occurred in 4 of 17 patients (24%) receiving rhEPO at a dose of 1,200 to 1,600 U\/kg intravenously (IV) twice weekly.","label":0,"label_text":"Not-Related"}
+{"text":"Each had angiographically documented bilateral high-grade stenosis or occlusion of the internal carotid arteries.","label":0,"label_text":"Not-Related"}
+{"text":"PURPOSE: Choroidal detachment is a known complication of topical hypotensive agents when used to treat eyes sensitized by prior surgery.","label":0,"label_text":"Not-Related"}
+{"text":"Immunoperfusion with staphylococcal protein A is the most effective treatment available and this new technique appears promising.","label":0,"label_text":"Not-Related"}
+{"text":"We report two new cases of sarcoidosis in two patients with hepatitis C virus infection treated with interferon alfa and ribavirin.","label":1,"label_text":"Related"}
+{"text":"Reye syndrome (RS) is believed to occur infrequently among children receiving long-term aspirin therapy.","label":1,"label_text":"Related"}
+{"text":"During the past 2 years since new legislation for organ transplantation from brain-dead donors came into effect in Japan, 3 cardiac transplants have been carried out, 2 of which were performed at the National Cardiovascular Center (NCVC).","label":0,"label_text":"Not-Related"}
+{"text":"The decedent was also prescribed tramadol, gabapentin, cetirizine, modafinil, carisoprodol, and Xyrem.","label":0,"label_text":"Not-Related"}
+{"text":"The tumor was not adherent to the dura, and its appearance was that of a typical neurilemmoma.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: With increasing clinical use of terlipressin and an increasing incidence of obesity and non-alcoholic fatty liver disease-related cirrhosis, the incidence of these serious complications is likely to rise.","label":0,"label_text":"Not-Related"}
+{"text":"Parkinson disease: an update.","label":0,"label_text":"Not-Related"}
+{"text":"A third patient developed a severe pityrias rosea-like eruption.","label":0,"label_text":"Not-Related"}
+{"text":"Hypercontractile heart failure caused by catecholamine therapy in premature neonates.","label":0,"label_text":"Not-Related"}
+{"text":"This observation supports the notion of a possible pro-epileptogenic effect of opioid substances in association with metabolic and other toxic factors.","label":0,"label_text":"Not-Related"}
+{"text":"One minute after intrathecal injection of 3.5 mL of solution, the patient developed myoclonus of his lower extremities.","label":0,"label_text":"Not-Related"}
+{"text":"This article does not question the efficacy of the V.A.C. technique in the treatment of difficult wounds, but focuses on raising the index of suspicion of toxic shock syndrome in patients with wounds managed with the V.A.C. who develop early signs or symptoms that may be consistent with the diagnosis.","label":0,"label_text":"Not-Related"}
+{"text":"PATIENTS: One patient with mucositis secondary to chemotherapy.","label":0,"label_text":"Not-Related"}
+{"text":"Therefore we had suggested that introducing tacrolimus could be a therapeutic option.","label":0,"label_text":"Not-Related"}
+{"text":"Histopathology revealed differentiated adult Wilms' tumour with renal angiosarcoma, whereas the pathology of the para-aortic lymph node and bone metastasis revealed angiosarcoma only.","label":0,"label_text":"Not-Related"}
+{"text":"We describe the case of a woman so treated with this protocol who subsequently developed severe life threatening laryngeal necrosis.","label":0,"label_text":"Not-Related"}
+{"text":"Discontinuation of the therapeutic agent led to the amelioration of the clinical profile in all the patients whereas a patient died 40 d after hospital admission due to sepsis, despite acute liver disease improvement.","label":0,"label_text":"Not-Related"}
+{"text":"This occurred consecutively after the administration of chemotherapy, during the ensuing period of myelosuppression.","label":0,"label_text":"Not-Related"}
+{"text":"Histological examination of the kidneys showed tubular dysgenesis with poor differentiation of the proximal tubules.","label":0,"label_text":"Not-Related"}
+{"text":"Some hiccups are associated with certain diseases or occur postsurgically, and life-restricting intractable hiccups should be treated.","label":0,"label_text":"Not-Related"}
+{"text":"We report a patient with pulmonary adenocarcinoma complicated by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) following systemic chemotherapy with cisplatin (CDDP) and vindesine (VDS).","label":1,"label_text":"Related"}
+{"text":"Six weeks after PDT, a concentric area of RPE atrophy was clearly visible on fluorescein angiogram.","label":0,"label_text":"Not-Related"}
+{"text":"She was treated by right axillo-femoral bypass, removal of the aortic prosthesis and direct aortic suture.","label":0,"label_text":"Not-Related"}
+{"text":"Chest roentgenogram showed infiltration in the left lung field, and laboratory data revealed eosinophilia.","label":0,"label_text":"Not-Related"}
+{"text":"Report of two cases and concise review of the literature.","label":0,"label_text":"Not-Related"}
+{"text":"Within 4 weeks of the start of the antiandrogen therapy, verbal and physical aggressivity had ceased; activity disturbances such as agitation, pacing, and restlessness were markedly reduced.","label":0,"label_text":"Not-Related"}
+{"text":"Methotrexate (MTX) is a commonly used second line agent for RA, and there have been several recent reports of Epstein-Barr virus (EBV)-associated polyclonal B cell lymphoproliferative disorder in MTX-treated RA patients.","label":1,"label_text":"Related"}
+{"text":"However, it was rarely reported in ECT sessions for psychiatric patients who needed concurrent antibiotic treatments.","label":0,"label_text":"Not-Related"}
+{"text":"Four dogs developed cutaneous lesions following the administration of various antibiotics.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: The combination of these drugs, even small doses, caused toxicity.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: In conclusion, because of increased lymphoid malignancy risk, ovarian masses in JRA patients should be carefully evaluated.","label":0,"label_text":"Not-Related"}
+{"text":"Agranulocytosis induced by vancomycin in an ESRD patient on CAPD.","label":1,"label_text":"Related"}
+{"text":"With initiation of treatment, her pulmonary symptoms and radiographic and spirometric evidence of BO resolved.","label":0,"label_text":"Not-Related"}
+{"text":"A 36-year-old man with AIDS and relapsing, nonproductive cough.","label":0,"label_text":"Not-Related"}
+{"text":"Only mild pericellular fibrosis was present in the liver biopsy specimen obtained shortly after abstinence, but after 5 years the second liver biopsy showed that thin septum-like fibrosis that formed portal-to-portal and portal-to-central linkage had developed and ground-glass hepatocytes had emerged extensively.","label":0,"label_text":"Not-Related"}
+{"text":"We report an unusual case of catheter fracture as a consequence of pinchoff syndrome, and discuss the potential methods to avoid this complication and its evolution.","label":0,"label_text":"Not-Related"}
+{"text":"In summary, we report herein the first case of SIADH believed to be an adverse effect of mizoribin, which may therefore needed to be added to the list of drugs which can induce SIADH.","label":1,"label_text":"Related"}
+{"text":"Physicians should be aware of the risk of severe AIHA in CLL patients with a history of AIHA or positivation of the DAT during previous fludarabine administration, or in case of secondary fixation of complement to the red cell membrane occurring during fludarabine treatment.","label":1,"label_text":"Related"}
+{"text":"Subsequent joint aspiration revealed monosodium urate monohydrate crystals.","label":0,"label_text":"Not-Related"}
+{"text":"The membranes resolved and visual acuity improved with topical corticosteroid treatment alone but recurred in all patients on cessation of treatment.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Two weeks after treatment of the injury with botulinum toxin, the patient reported complete resolution of his symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"By means of the in vitro heparin-induced platelet activation (HIPA) assay it was shown that standard heparin and the LMW heparins Fragmin and Fraxiparin (Sanofi Labaz, Munich, FRG), as well as the enoxaparine Clexane (Nattermann, Cologne, FRG), all induced platelet activation with the patient's serum.","label":1,"label_text":"Related"}
+{"text":"On day 28 of the treatment, his serum calcium levels had reached 3.55 mmol\/l, and his urinary calcium excretion had also increased from 0.008 g\/day to 0.475 g\/day.","label":0,"label_text":"Not-Related"}
+{"text":"Though hypotension, dry mouth, and constipation are well-documented possible adverse effects, the possibility of clonidine-induced bradycardia is less well recognized and is rare.","label":1,"label_text":"Related"}
+{"text":"PURPOSE: The aim of the study is to describe a case of suspected endotoxin-induced uveitis associated with septic endogenous endophthalmitis followed by antibiotic-induced endotoxemia.","label":0,"label_text":"Not-Related"}
+{"text":"Patient had primary polydipsia and secondarily developed hyponatremia.","label":0,"label_text":"Not-Related"}
+{"text":"One expert would order a CT scan to rule out facial fractures (Dr.","label":0,"label_text":"Not-Related"}
+{"text":"Cyclosporine was discontinued, and plasmapheresis was started.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSION: The new quinolone derivatives (levofloxacin, sparfloxacin, grepafloxacin, trovafloxacin, gatifloxacin and moxifloxacin), also called gyrase inhibitors, are known for their potential to cause central nervous system-related adverse effects, including headache, dizziness and insomnia.","label":1,"label_text":"Related"}
+{"text":"Small bowel haemorrhage due to cytomegalovirus vasculitis.","label":0,"label_text":"Not-Related"}
+{"text":"Her initial EEG showed a pattern of spindle coma with some responsivity of the background.","label":0,"label_text":"Not-Related"}
+{"text":"Three of these patients had convulsions attributed to imipenem\/cilastatin; 3.6% of the patients had seizure, or 2% of imipenem\/cilastatin administrations was followed by a seizure attack.","label":1,"label_text":"Related"}
+{"text":"Statins are associated with a small, dose-related risk of myopathy, myositis, and rhabdomyolysis.","label":0,"label_text":"Not-Related"}
+{"text":"We report on three cases wherein treatment of dexmedetomidine-induced bradycardia with i.v. glycopyrrolate (5.0 microg\/kg) not only resulting in resolution of bradycardia but also resulting in an exaggerated increase of arterial blood pressure.","label":1,"label_text":"Related"}
+{"text":"Veno-occlusive disease (VOD) of the liver is mainly described after chemo-irradiation conditioning regimens during haematopoietic stem cell transplantation (SCT) and has been sporadically reported after kidney and liver transplantation.","label":0,"label_text":"Not-Related"}
+{"text":"Neonatal venous cerebral hemorrhage.","label":0,"label_text":"Not-Related"}
+{"text":"Two patients with HLH developed etoposide-related secondary acute myeloid leukemia (sAML) following therapy for HLH.","label":1,"label_text":"Related"}
+{"text":"In association with this tocolysis, urinary calculus of magnesium ammonium phosphate occurred at 34 weeks gestation.","label":1,"label_text":"Related"}
+{"text":"This reaction was considered to fit with coronary vasospasm.","label":0,"label_text":"Not-Related"}
+{"text":"It also shows severe relapse after withdrawal of fenclofenac.","label":0,"label_text":"Not-Related"}
+{"text":"During and after IFN therapy we should consider the possibility of occurrence of IDDM as well as other autoimmune diseases and observe the clinical course carefully.","label":1,"label_text":"Related"}
+{"text":"With the alarming increase in incidence of tuberculosis in the United States over the past several years a review of anti-tuberculosis medications and their potential side effects is warranted.","label":0,"label_text":"Not-Related"}
+{"text":"In addition, lipid abnormalities (mainly hypertriglyceridaemia) are also found more frequently in hypertensive patients than in normotensives.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To report a patient with a large gastrointestinal stromal tumor (GIST) who received multiple blood transfusions intraoperatively and developed a transfusion-related acute lung injury (TRALI).","label":0,"label_text":"Not-Related"}
+{"text":"The clinical and electrophysiological features of the case are discussed.","label":0,"label_text":"Not-Related"}
+{"text":"CONCLUSIONS: Exposure to vanadium can cause a metal fume fever-like syndrome associated with neutrophilic alveolitis.","label":0,"label_text":"Not-Related"}
+{"text":"Moxalactam is more likely to be associated with platelet dysfunction.","label":1,"label_text":"Related"}
+{"text":"During the first treatment, dysarthria and ataxia were seen after completion of the patient's eighth and final dose of HDARAC.","label":1,"label_text":"Related"}
+{"text":"Successful liver transplantation and treatment of recurrent hepatitis C using pegylated alpha-interferon in a patient with Churg-Strauss disease.","label":0,"label_text":"Not-Related"}
+{"text":"No published reports of priapism with antidepressants were located, but 11 cases have been reported to the manufacturers.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: Two patients with exudative age-related macular degeneration were treated sequentially with an intravitreal injection of bevacizumab and developed signs of severe but painless infectious endophthalmitis 2 days later.","label":1,"label_text":"Related"}
+{"text":"We conclude that tuberculosis is an important diagnostic consideration for CAPD patients with peritonitis that is refractory to broad-spectrum antibiotics.","label":0,"label_text":"Not-Related"}
+{"text":"CASE PRESENTATION: A 33-month-old girl was diagnosed with CF at 6 months of age.","label":0,"label_text":"Not-Related"}
+{"text":"We report the specifics of 12 cases of severe hypertension after the intraoperative use of topical phenylephrine, submucosal epinephrine, or both.","label":1,"label_text":"Related"}
+{"text":"Diagnosis of HUS was confirmed histologically in 13 patients and based on clinical findings in the other 15.","label":0,"label_text":"Not-Related"}
+{"text":"Phenytoin, verapamil, and acetazolamide were ineffective, but tocainide yielded good results.","label":0,"label_text":"Not-Related"}
+{"text":"Well-known signs of methotrexate toxicity include bone marrow suppression and oral and gastrointestinal ulceration.","label":1,"label_text":"Related"}
+{"text":"Hyperphosphatemia is an infrequent complication of the tumor lysis following induction therapy for lymphoproliferative disorders that can result in acute renal failure.","label":0,"label_text":"Not-Related"}
+{"text":"That review suggested that patients receiving anti-D IGIV be monitored for those and other potential complications of hemoglobinemia, particularly disseminated intravascular coagulation (DIC).","label":1,"label_text":"Related"}
+{"text":"This case presentation is of a patient who had the clinical appearance of epiglottitis, but actually had an oro-pharyngeal dystonic reaction to prochlorperazine.","label":1,"label_text":"Related"}
+{"text":"Since its introduction to the market, there have been various dermatologic side effects reported in the literature, the most well known being hand-foot skin reaction.","label":0,"label_text":"Not-Related"}
+{"text":"Confocal microscopy findings of Acanthamoeba keratitis.","label":0,"label_text":"Not-Related"}
+{"text":"Transient high rates of infusion of Intralipid appears to be a factor in the aetiology of the condition.","label":0,"label_text":"Not-Related"}
+{"text":"Following CaEDTA therapy, continued recovery of conduction velocities, amplitude of compound muscle action potential, and diminution of conduction block at elbow were observed within a few months.","label":0,"label_text":"Not-Related"}
+{"text":"He had an immediate hypersensitivity reaction during the initiation of the MTX infusion with diffuse urticaria, facial swelling, cough, and chest tightness.","label":1,"label_text":"Related"}
+{"text":"The patient's serum ammonia level returned to normal by hospital day 4, and he was discharged to his group home.","label":0,"label_text":"Not-Related"}
+{"text":"Attempts at symptom control are not always effective because of lack of clarity about the underlying aetiology.","label":0,"label_text":"Not-Related"}
+{"text":"METHOD: We describe two patients who presented with diabetic ketoacidosis after treatment with quetiapine and risperidone, respectively.","label":1,"label_text":"Related"}
+{"text":"The mild immunosuppression that occurs with methotrexate therapy probably places patients with rheumatoid arthritis at added risk of developing lymphoproliferative diseases, but coincidence cannot be excluded.","label":1,"label_text":"Related"}
+{"text":"A fecal fat 72-hour study revealed a coefficient of absorption of 50%.","label":0,"label_text":"Not-Related"}
+{"text":"An episode of leukoencephalopathy is reported in a 13-year-old girl who, after standard radiotherapy for a posterior fossa medulloblastoma, received 8 treatments with a protocol containing a 4-hour infusion of 500 mg\/m2 methotrexate and 12 mg intrathecal methotrexate.","label":1,"label_text":"Related"}
+{"text":"We report of a case of severe disseminated U. urealyticum infection in a 35-y-old kidney transplanted patient with CVID.","label":0,"label_text":"Not-Related"}
+{"text":"Concentric retinal pigment epithelium atrophy after a single photodynamic therapy.","label":0,"label_text":"Not-Related"}
+{"text":"She was found to have high protamine-specific, as well as insulin-specific, IgE levels, and because of her poor response to regular insulin desensitization, she was desensitized to both regular and NPH insulin.","label":0,"label_text":"Not-Related"}
+{"text":"There is no effective monitoring to prevent this side effect.","label":0,"label_text":"Not-Related"}
+{"text":"MRI revealed white matter abnormalities that were not present on the pretreatment scan.","label":0,"label_text":"Not-Related"}
+{"text":"We obtained the following results.","label":0,"label_text":"Not-Related"}
+{"text":"Lymphocytes obtained from a hyperthyroid patient treated with propylthiouracil without complications failed to show evidence of sensitization.","label":0,"label_text":"Not-Related"}
+{"text":"The second is a case of superficial invasion of Candida in a stitch ulcer.","label":0,"label_text":"Not-Related"}
+{"text":"After previously tolerating ECT well, introduction of moxifloxacin for a respiratory tract infection was associated with prolonged seizure duration despite complete resolution of her respiratory complaint.","label":0,"label_text":"Not-Related"}
+{"text":"Although her drowsiness improved, she complained of piloerection throughout her body.","label":0,"label_text":"Not-Related"}
+{"text":"It gives the radiological and CT scan findings and the important role played by them in the diagnosis of this syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Solid organ transplant recipients can experience serious disease and death from infection due to the parasitic roundworm Strongyloides stercoralis.","label":0,"label_text":"Not-Related"}
+{"text":"Where over-usage occurs a state of diminished airways response seems to result: it is also possible that the convulsions which occurred in one case may be related to such abuse.","label":0,"label_text":"Not-Related"}
+{"text":"No fever, elevated WBC count or significant electrolyte imbalance was found.","label":0,"label_text":"Not-Related"}
+{"text":"Thus, we believe that the combination of sodium thiosulfate with cinacalcet and paracalcitol is effective for the treatment of calciphylaxis with secondary hyperparathyroidism.","label":0,"label_text":"Not-Related"}
+{"text":"A case is reported of theophylline intoxication due to a dramatic decrease in theophylline clearance following concomitant administration of viloxazine.","label":1,"label_text":"Related"}
+{"text":"Given the wide use of gemcitabine following chemoradiation for pancreatic cancer, providers should be aware of this potential complication.","label":0,"label_text":"Not-Related"}
+{"text":"One patient underwent coronary angiography which disclosed no pathology, but following which, while on a calcium channel blocking agent regimen, he had an uneventful course of chemotherapy with cisplatin.","label":0,"label_text":"Not-Related"}
+{"text":"The relation of TNF-alpha antagonist therapy to demyelinating disease\/multiple sclerosis is explored.","label":0,"label_text":"Not-Related"}
+{"text":"A hypertensive women was treated throughout pregnancy with propranolol 40 mg daily without complication.","label":0,"label_text":"Not-Related"}
+{"text":"METHODS: An 8-year-old boy with osteomyelitis was referred due to visual disturbance.","label":0,"label_text":"Not-Related"}
+{"text":"The patient was successfully treated with prednisone 1 mg\/kg\/day for 2 weeks.","label":0,"label_text":"Not-Related"}
+{"text":"Our patient had headache, mild fever, nausea, vomiting, rash, and eosinophilia after 3 weeks of disulfiram therapy.","label":1,"label_text":"Related"}
+{"text":"Eight of the patients required chelation therapy.","label":0,"label_text":"Not-Related"}
+{"text":"In this report we described a case of juvenile idiopathic arthritis patient who developed thymic enlargement (true thymic hyperplasia), mediastinal lymphadenopathy and pleurisy associated with systemic symptoms under Etanercept treatment.","label":1,"label_text":"Related"}
+{"text":"We describe the first published case of intoxication with both drugs.","label":0,"label_text":"Not-Related"}
+{"text":"Management consisted of supportive care including antibiotics and antifungal therapy, transfusion of red blood cells and fresh frozen plasma.","label":0,"label_text":"Not-Related"}
+{"text":"In the case of atypical neuroleptics such as olanzapine a low but still considerable D2 dopamine receptor occupancy may be compensated by the 5-HT2 antagonism.","label":0,"label_text":"Not-Related"}
+{"text":"As nonallergic increases in tryptase have been observed, e.g. during angio-oedema from angiotensin-converting enzyme inhibitors, and bradykinin itself can degranulate mast cells acutely, we interpret the reaction as a class effect.","label":0,"label_text":"Not-Related"}
+{"text":"OBJECTIVE: To report 2 cases of nonconvulsive status epilepticus (NCSE) following infusion of ifosfamide.","label":1,"label_text":"Related"}
+{"text":"We present a case of significant over-anticoagulation temporally associated with a bout of protracted diarrhea in a patient on warfarin therapy.","label":1,"label_text":"Related"}
+{"text":"Cerebral blood flow and blood pressure monitoring, together with intensive antihypertensive therapy, are necessary to reduce the risk of hyperperfusion syndrome after vertebral stenting.","label":0,"label_text":"Not-Related"}
+{"text":"Our study also suggests that switching from bromocriptine to pergolide improves nocturia, thereby improving sleep status of patients with Parkinson's disease.","label":0,"label_text":"Not-Related"}
+{"text":"Oral pilocarpine tablets, as well as another muscarinic agent (cevimeline), have recently been approved for the treatment of dry mouth (xerostomia).","label":0,"label_text":"Not-Related"}
+{"text":"The current article highlights the hepatotoxic potency of a widely administered therapeutic agent and illustrates the importance of clinical surveillance especially in patients with previous hepatic diseases.","label":0,"label_text":"Not-Related"}
+{"text":"The co-occurrence of bingeing, irritability and anterograde amnesia is suggestive of a drug-induced Kleine-Levin Syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"Although not previously known, it was at this stage discovered that the patient had received treatment with anti-leprosy drugs nearly three years before presentation in this country.","label":0,"label_text":"Not-Related"}
+{"text":"All three cases showed extensive fibrin deposition in the kidneys and lungs, the appearances of the renal lesions being similar to those seen in the haemolytic-uraemic syndrome.","label":0,"label_text":"Not-Related"}
+{"text":"This case illustrates a successful treatment of BO with selective tumor necrosis factor-alpha blockade.","label":0,"label_text":"Not-Related"}
+{"text":"Kalimate was administered orally and as an enema suspended in 20% dextrose water to treat hyperkalemia.","label":0,"label_text":"Not-Related"}
+{"text":"The visual loss in this patient seems to result from phenol neurotoxicity rather than mechanical compression of the intraorbital optic nerve.","label":1,"label_text":"Related"}
+{"text":"Zolpidem tissue concentrations in a multiple drug related death involving Ambien.","label":1,"label_text":"Related"}
+{"text":"Dementia affects up to 70% of nursing-home patients, and more than 90% of them exhibit aggressive or agitated behavior or severe depression.","label":0,"label_text":"Not-Related"}
+{"text":"We report the first case of acute renal failure with hyperkalemia associated with the recently marketed direct renin inhibitor aliskiren.","label":1,"label_text":"Related"}
+{"text":"Prompt hemostasis was achieved in half of the patients with their coagulation profile being restored within 4 hours after the administration of the first dose of rFVIIa.","label":0,"label_text":"Not-Related"}
+{"text":"These results indicate that CFSE dilution assay will be useful for the diagnosis and monitoring of drug hypersensitivity.","label":0,"label_text":"Not-Related"}
+{"text":"She was administered metoclopramide because of nausea and, within 2 hours, developed agitation, dysarthria, diaphoresis, and a movement disorder.","label":1,"label_text":"Related"}
+{"text":"Clearly, patience is important during hepatitis C therapy in order to avoid unnecessary examinations and to promote successful outcomes.","label":0,"label_text":"Not-Related"}
+{"text":"Localized panniculitis and subsequent lipoatrophy with subcutaneous glatiramer acetate (Copaxone) injection for the treatment of multiple sclerosis.","label":1,"label_text":"Related"}
+{"text":"Two cases of childhood-onset schizophrenia associated with clozapine-induced akathisia responsive to beta-blocker treatment are described.","label":1,"label_text":"Related"}
+{"text":"Despite treatment in the intensive care unit, the woman died on the sixth day after admission.","label":0,"label_text":"Not-Related"}
+{"text":"Though the voluntary recall was in effect, the family already had a bottle of the medication at home.","label":0,"label_text":"Not-Related"}
+{"text":"Despite withdrawal of antiretroviral therapy a proximal myopathy developed.","label":0,"label_text":"Not-Related"}
+{"text":"Inflammation may be exacerbated by pre-existing dermatologic conditions.","label":0,"label_text":"Not-Related"}
+{"text":"PURPOSE: Standard therapy of mycotic aneurysms in the descending aorta consists of thoracotomy and in situ graft placement or extraanatomic bypass.","label":0,"label_text":"Not-Related"}
+{"text":"PURPOSE: The aim of this article was to review the most important data in the literature about SSEH and to propose clopidogrel (Plavix) therapy as a risk factor.","label":0,"label_text":"Not-Related"}
+{"text":"Effective treatment includes daily oral hygiene and periodic professional prophylaxis.","label":0,"label_text":"Not-Related"}
+{"text":"One patient who received clindamycin had liver biopsy findings of marked cholestasis, portal inflammation, bile duct injury and bile duct paucity (ductopenia).","label":1,"label_text":"Related"}
+{"text":"There have been few reports on the imaging diagnosis and treatment of infection of interbody cages used in posterior lumbar interbody fusion.","label":0,"label_text":"Not-Related"}
+{"text":"After infliximab treatment, additional sleep studies revealed an increase in the number of apneic events and SaO2 dips suggesting that TNFalpha plays an important role in the pathophysiology of sleep apnea.","label":1,"label_text":"Related"}
+{"text":"Treprostinil is labeled for treatment of pulmonary hypertension with New York Heart Association (NYHA) Class II, III and IV symptoms.","label":0,"label_text":"Not-Related"}
+{"text":"Neuroleptic drug induced downregulation of nigral dopaminergic neurons may help to explain the persistent parkinsonism found in many patients after withdrawal of medication.","label":0,"label_text":"Not-Related"}
+{"text":"The atypical antipsychotics have advanced the treatment of schizophrenia and have proved to be effective agents in treating other disorders with or without psychotic features.","label":0,"label_text":"Not-Related"}
+{"text":"Visceral leishmaniasis and macrophagic activation syndrome in a patient with rheumatoid arthritis under treatment with adalimumab.","label":1,"label_text":"Related"}
+{"text":"Neurologic symptoms were usually absent, but 49% of the patients developed adult respiratory distress syndrome (ARDS).","label":0,"label_text":"Not-Related"}
+{"text":"Thus, further therapy must not be withheld.","label":0,"label_text":"Not-Related"}
+{"text":"RTA is one type of nephrotoxicity induced by FK506, and it is reversible in mild cases when appropriately treated.","label":1,"label_text":"Related"}
+{"text":"Allergic contact and photocontact dermatitis due to psoralens in patients with psoriasis treated with topical PUVA.","label":0,"label_text":"Not-Related"}
+{"text":"Review of antithyroid drug use during pregnancy and report of a case of aplasia cutis.","label":0,"label_text":"Not-Related"}
+{"text":"We report a patient with pulmonary adenocarcinoma complicated by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) following systemic chemotherapy with cisplatin (CDDP) and vindesine (VDS).","label":1,"label_text":"Related"}
+{"text":"His impaired memory was found to be due to the atenolol he was on and he made a complete recovery on withdrawing the beta-blocker.","label":1,"label_text":"Related"}
+{"text":"We present a patient who developed skin lesions typical of disseminated superficial porokeratosis (DSP) while on immunosuppressive therapy for pemphigus foliaceus.","label":0,"label_text":"Not-Related"}
+{"text":"Severe autologous GVHD after hematopoietic progenitor cell transplantation for multiple myeloma.","label":0,"label_text":"Not-Related"}
+{"text":"Eleven patients developed infection requiring hospitalization while taking leflunomide including: lower respiratory tract infections (3), cellulitis (2), disseminated herpes zoster (2), probable TB liver (1), abdominal sepsis (1), mycotic aneurysm (1) and gastroenteritis (1).","label":1,"label_text":"Related"}
+{"text":"Amantadine was therefore discontinued.","label":0,"label_text":"Not-Related"}
+{"text":"The case is presented of a 39-year-old Type 1 diabetic patient of 22 years duration with recurrent hypoglycaemic comas.","label":0,"label_text":"Not-Related"}
+{"text":"Miconazole as a treatment for Candida septicaemia.","label":0,"label_text":"Not-Related"}
+{"text":"A 14-year-old female developed systemic lupus erythematosus (SLE)-like symptoms, rash, fever, leukopenia and positive anti-nuclear antibody (ANA) two weeks after administration of carbamazepine (CBZ; Tegretol) used against benign Rolandic epilepsy.","label":1,"label_text":"Related"}
+{"text":"Two patients treated with 5-fluorouracil (5-FU) for disseminated adenocarcinoma of the colon developed cerebellar dysfunction typical of 5-FU neurotoxicity.","label":1,"label_text":"Related"}
+{"text":"Diarrhea-associated over-anticoagulation in a patient taking warfarin: therapeutic role of cholestyramine.","label":1,"label_text":"Related"}
+{"text":"In more than 6,000 patient applications of rapid atrial pacing, there has been only one failure to convert the tachycardia.","label":0,"label_text":"Not-Related"}
+{"text":"Moderate lymphocytic infiltration of the substantia propria of the conjunctiva of both upper and lower lid specimens was present, as was scarring and keratinization of the epithelium.","label":0,"label_text":"Not-Related"}
+{"text":"This article presents a rare case of acute toxic hepatitis in thirty-one-year old primigravida.","label":0,"label_text":"Not-Related"}
+{"text":"Catatonia associated with disulfiram therapy.","label":1,"label_text":"Related"}
+{"text":"A 27-year-old man who had a history of bronchial asthma, eosinophilic enteritis, and eosinophilic pneumonia presented with fever, skin eruptions, cervical lymphadenopathy, hepatosplenomegaly, atypical lymphocytosis, and eosinophilia two weeks after receiving trimethoprim (TMP)-sulfamethoxazole (SMX) treatment.","label":1,"label_text":"Related"}
+{"text":"CONCLUSIONS: Intravitreal injection of triamcinolone acetonide may be an additional tool in the treatment of therapy-resistant cystoid macular edema after penetrating keratoplasty.","label":0,"label_text":"Not-Related"}
+{"text":"The operation was accomplished with cardiopulmonary bypass.","label":0,"label_text":"Not-Related"}
+{"text":"Idiosyncratic pulmonary reactions to nitrofurantoin are not unusual, often presenting as eosinophilic pneumonia.","label":1,"label_text":"Related"}
+{"text":"Four days after intravenous Zoledronic acid, the patient presented to emergency room with complaints of carpopedal spasm and bronchospasm.","label":1,"label_text":"Related"}
+{"text":"BACKGROUND: Gemcitabine has mild renal toxicity, but cases of gemcitabine-associated hemolytic-uremic syndrome (HUS) have been reported.","label":1,"label_text":"Related"}
+{"text":"We report three cases of post-transplant lymphoproliferative disorder (PTLD) in the context of autologous stem cell transplantation (ASCT) for multiple myeloma (MM) and non-Hodgkin's lymphoma.","label":0,"label_text":"Not-Related"}
+{"text":"A fifty-six year old black man with stage D carcinoma of the prostate was treated weekly with 5-fluorouracil 750 mg\/m2 for twenty-four consecutive doses.","label":0,"label_text":"Not-Related"}
+{"text":"Acute myeloid leukaemia with t(8;16)(p11;p13) in a child after intrauterine X-ray exposure.","label":0,"label_text":"Not-Related"}
+{"text":"Moreover, meningiomas in the lumbosacral region are very rare.","label":0,"label_text":"Not-Related"}
+{"text":"Case 1, a 62-year-old woman, developed bilateral optic neuritis with decreased sensation of vibration and increased deep tendon reflex in the lower extremities after a seven-month use of recombinant interferon alpha-2a for chronic active hepatitis C.","label":1,"label_text":"Related"}
+{"text":"A 40-year-old man with advanced HIV infection and Mycobacterium avium complex infection experienced rapid cognitive decline after commencement of ethambutol, and symptoms fully resolved with cessation.","label":1,"label_text":"Related"}
+{"text":"Individual pharmacokinetics were assessed using Bayesian analysis.","label":0,"label_text":"Not-Related"}
+{"text":"Although the current metabolism of the 2 drugs in combination is poorly understood, the potential for serious interactions seems to exist in the rapidly growing population of persons with asthma, for whom they may be prescribed.","label":0,"label_text":"Not-Related"}
+{"text":"After admission, he was found to have retrograde shunt infection from peritonitis caused by cholecystitis.","label":0,"label_text":"Not-Related"}
+{"text":"All patients improved and 6 are in complete remission.","label":0,"label_text":"Not-Related"}
+{"text":"RESULTS: Similar to previous findings of drug-induced vortex keratopathy, atovaquone vortex keratopathy is presumably caused by its lipophilic properties.","label":1,"label_text":"Related"}
+{"text":"Anticonvulsant hypersensitivity syndrome associated with Bellamine S, a therapy for menopausal symptoms.","label":1,"label_text":"Related"}