What is the best way to get from one place to another?
The term "best" is relative to your individual preferences and circumstances. 

In general, how to get from one place to another depends on several key factors, such as the distance between these two places, available methods of transportations, and the amount of money that you are willing to spend. Additional factors to consider are whether you have a preferred method of transportation and how much time you are willing to spend on this trip. Cheaper transportation options may take a longer time. 

The methods of transportation include airplanes, trains, ships or ferries, busses, and cars, but not all locations have all these transportation methods available.

Usually, if the two places are relatively close to each other, a bus or a train may be a good option. If public transportation between these two places is not well established, then a personal car may be a reasonable alternative.

In some circumstances, when the distance between the two place is very short, less than three miles or so, walking may be your best option. This, of course, depends on your ability and willingness to walk that distance.

If the two places are relatively far, usually more than a couple hundred miles, an airplane may be a good option to consider.