Text: There are inherent differences between the use of a NOEC or LOEC derived from hypothesis testing to estimate a safe concentration, and the use of a LC, IC, EC, or other point estimates derived from curve fitting, interpolation, etc.
Entailment: LOECs calculated through testing the hypothesis are different from ICs found through interpolation.
Contradiction: LOECs found via hypothesis testing are almost identical to ICs calculated via interopolation.