Domain: Healthcare — Medicine
Target concept: Stability Testing of Drugs (High-Temperature Method)

Video generation prompt: A 1 g amount of sodium penicillin powder was placed in a porcelain dish and dried in a 50°C constant temperature drying oven for 2 hours. After removal, the powder's color and solubility were observed.

Evaluation guide:
(i) Target concept: Thermal degradation of sodium penicillin under controlled dry heat, manifesting as solubility loss without visible color change.
Minimum mechanism: Sodium penicillin must remain chemically intact enough to retain white appearance but undergo sufficient β-lactam ring cleavage to reduce aqueous solubility, requiring dry heat (not humid or oxidative conditions) and absence of catalytic impurities.
(ii)Storyline: [Phase 1: Setup] White powder is placed into porcelain dish (fixed viewpoint, frontal angle, dish centered). [Phase 2: Intervention] Dish is inserted into oven; oven door closes fully (no cut-away; continuity preserved). [Phase 3: Implied Duration] Oven remains static: no time-lapse, no clock, but no action occurs inside oven (no steam, glow, or motion). [Phase 4: Observation] Dish is removed; same powder is shown; water is added; stillness follows; undissolved particles remain visible. [Visibility constraints] All phases use consistent lighting, fixed camera height/angle, and no occlusion of dish/powder surface during critical observations.

Manual:
Experimental Procedure
1. Place 1 g sodium penicillin powder into a porcelain dish.
2. Insert dish into a 50°C constant temperature drying oven.
3. Dry for 2 hours (implied duration).
4. Remove dish and observe powder color and solubility in water.
Observation of Experimental Phenomena
- Powder remains white before and after drying.
- After water addition, undissolved white particles persist, indicating reduced solubility.
Summary of Experimental Principles
Sodium penicillin degrades upon heating, causing loss of solubility while retaining white color — demonstrating thermal instability per Stability Testing (High-Temperature Method).

Prompt Grounding rubric:
level_1: No porcelain dish appears, no white powder representing the sodium penicillin is shown, no drying oven is present, and no placement or post-drying observation step occurs.
level_2: The porcelain dish is shown but is empty or holds the wrong material (a liquid, a tablet, or a colored powder); the oven shown doesn't read as a lab drying oven (e.g., it looks like a microwave or has no door); or the powder is placed into a different container such as a beaker or vial.
level_3: A porcelain dish holding a white, powdery substance is shown; the powder is placed into the dish by hand; a benchtop drying oven with a door and chamber is present and the dish is put inside it; a later shot shows someone looking at the dish again after drying, but there is no clear visual difference shown between the powder's state before and after the oven.
level_4: All conditions for score 3 are met, and the amount of white powder in the dish looks consistent with roughly 1 gram (a small heap, not a spoonful or a thin dusting); the powder goes into the dish before the dish goes into the oven; the dish is shown either inside the oven chamber or the oven door closed around it during drying; the same dish with powder reappears for the post-drying look.
level_5: All conditions for score 4 are met, and the sequence reads as one continuous story with no confusing cuts: powder into dish, dish into oven, door closed, oven left undisturbed, dish taken back out and held still for the observer, with the same dish and the same powder recognizable at every step.

Scientific and Causal Correctness rubric:
level_1: The powder turns blue, green, or black; it dissolves on its own without any water being added; it melts or clumps irreversibly while still in the oven; or a color change happens before or during the oven step rather than only being checked afterward.
level_2: The powder stays white but already looks degraded (yellowed, browned, or caked) before it's even placed in the oven; water is never added for the solubility check, or the wrong liquid is used instead of water; the powder vanishes partway through drying.
level_3: The powder is white going into the oven and still white coming out; water is added to test solubility, but what happens next is unclear (no settling, no visible undissolved bits, no contrast between clear liquid and residue), so it's not obvious whether the solubility check actually shows anything.
level_4: All conditions for score 3 are met, and after water is added to the dried powder, undissolved white particles are clearly visible sitting in the liquid rather than fully dissolving, while the powder itself never bubbled, charred, or browned during drying, showing the causal chain of dried-but-still-white powder that has become harder to dissolve.
level_5: All conditions for score 4 are met, and the powder looks like loose, fine white crystals before drying and keeps that same fine white texture afterward; once water is added, the undissolved particles stay visibly suspended or settled for at least a couple of seconds rather than dissolving away; nothing in the shot suggests yellowing, browning, or clumping that would point to a different kind of degradation.

Spatiotemporal Consistency rubric:
level_1: The porcelain dish jumps to a different spot on the desk between shots; the penicillin powder disappears and reappears without being moved; the oven door swings open or shut in a single frame with no hinge motion; the room lighting jumps abruptly between shots (e.g., switching from daylight to warm tungsten light with no cause); the same dish looks like a different color or shape from one cut to the next.
level_2: The dish stays in one place but its surface flips between matte and glossy with no change in the room's light; the powder's texture flickers between fine crystals and a clumped mass between frames; the oven's interior light switches on or off with no visible cause; the hand placing the powder freezes for a beat and then jumps ahead.
level_3: The dish, the powder, and the oven keep their true shape, size, and position across the placement, insertion, and removal steps; the hand always approaches the dish from the same side; the room lighting stays close enough in color and angle from the first shot to the last that the dish and powder don't appear to shift illumination source; no part of the scene stretches or warps.
level_4: All conditions for score 3 are met, and the dish stays in the same orientation across every phase (placement, oven insertion, removal, water test); the oven door's opening and closing motion looks like a real hinge rather than sliding or vanishing; the person's hand and the dish stay proportionate to each other with no sudden change in relative size.
level_5: All conditions for score 4 are met, and the edge of the dish and the boundary of the powder line up smoothly from one frame to the next with no visible shake; any shadow cast by the hand or dish points the same way relative to the dish across every shot; the pace of the hand's motion during placement and during the water-addition observation looks the same speed rather than one part looking sped up or slowed down.