Domain: Healthcare — Pharmacy
Target concept: Regulatory effect of sustained-release coating on drug release

Video generation prompt: Two identical transparent containers are placed side by side, each filled with continuously flowing distilled water (at the same flow rate). A sustained-release coated tablet is placed in the left container, and a conventional tablet is placed in the right container. The release behavior is observed.

Evaluation guide:
(i) Target concept: Differential dissolution kinetics governed by polymer-based diffusion barrier integrity.
Minimum mechanism: Coating must be impermeable to water penetration on relevant timescale; conventional tablet matrix must be hydrophilic and erodible; flowing water prevents saturation, sustaining sink conditions for dissolution.
(ii)Storyline: [Frame 0–1] Two empty transparent containers enter view, side-by-side, water inlets activated → [Frame 2–3] Water flow stabilizes, menisci form → [Frame 4] Tablets placed simultaneously: coated tablet in left, conventional in right → [Frame 5–6] Coated tablet shows no surface change; conventional tablet begins localized surface roughening → [Frame 7–8] Cloudiness emerges and intensifies only around conventional tablet, confined to immediate periphery → [Frame 9–10] Left water remains crystal clear; right water turbidity persists and deepens; both tablets retain original position and macro-shape. Perspective: fixed frontal orthographic view, centered on container midlines, sufficient resolution to resolve tablet surface texture and water clarity differences.

Manual:
Experimental Procedure
1. Place two identical transparent containers side-by-side.
2. Fill both with continuously flowing distilled water at identical flow rates.
3. Place one sustained-release coated tablet in left container; one conventional tablet in right container.
Observation of Experimental Phenomena
Left container: tablet remains intact; surrounding water stays optically clear.
Right container: tablet surface disrupts; surrounding water becomes cloudy/turbid.
Summary of Experimental Principles
Sustained-release coating acts as a diffusion barrier, delaying drug dissolution and preventing rapid release; conventional tablet lacks this barrier, enabling immediate contact with water and rapid surface erosion/dissolution.

Prompt Grounding rubric:
level_1: No two side-by-side transparent containers are shown; no tablet appears in either container; no continuously flowing distilled water is visible; the scene does not match a two-container tablet comparison at all.
level_2: Two containers appear, but they are not placed next to each other or are not transparent; a tablet is present but misplaced (e.g., both tablets in one container, or a tablet floating with no visible placement); the water flow is missing or not clearly continuous in one or both containers.
level_3: Two identical transparent containers sit next to each other, each with distilled water flowing continuously; one solid tablet sits in the left container and one in the right; both are intact oral tablets (not capsules or loose powder), matching the prompt's description.
level_4: Everything above holds, and: the two tablets are visually distinguishable by their coating. The left (sustained-release) tablet shows a uniform matte or semi-opaque coating layer, while the right (conventional) tablet shows a bare, uncoated surface; the left/right assignment matches the prompt (sustained-release on the left, conventional on the right).
level_5: Everything above holds, and: both containers stay in the same arrangement and orientation for the entire clip; each tablet stays where it was placed at the bottom of its container, without drifting, rotating, or floating up; the coating difference established at level 4 stays visible from placement onward; the tubing, inlets, and container walls remain unobstructed and in frame throughout, with one steady camera framing and no cut, pan, or zoom.

Scientific and Causal Correctness rubric:
level_1: The left (sustained-release) and right (conventional) tablets show no behavioral difference: either both stay intact with clear water around them, or both erode and cloud the water similarly, so tablet type has no visible effect on release behavior.
level_2: Only one container shows a state change, but the pattern is wrong for the mechanism: e.g., the left (sustained-release) tablet is the one that erodes, sheds particles, or clouds its water; or cloudiness appears in the water before either tablet is placed; or the cloudy container is the wrong one relative to the prompt.
level_3: The left (sustained-release) tablet stays visibly intact with no surface change and clear water around it; the right (conventional) tablet shows localized surface disruption (pitting, fuzziness, or fine particles) and produces visible cloudiness in its surrounding water, with that cloudiness staying near the right tablet and not appearing near the left one.
level_4: Everything above holds, and: the cloudiness around the right tablet keeps building over time rather than staying static or fading; the water around the left tablet stays optically clear throughout, with no late-appearing haze, particles, or color shift, and no reversal where the left side turns cloudy instead.
level_5: Everything above holds, and: the cloudiness around the right (conventional) tablet clearly originates at the tablet's own surface rather than from the water inlet, and stays localized within about 1.5 times the tablet's height rather than spreading to fill the container, with a visibly clearer zone of water beyond it; the left (sustained-release) tablet shows no optical disturbance at all near its surface (no haze, no particle trail, no local water distortion), confirming it is not dissolving or swelling.

Spatiotemporal Consistency rubric:
level_1: One or both containers teleport, rotate, or change size mid-clip; a tablet appears or disappears abruptly instead of being placed by hand or dropped in; the water flow starts, stops, or reverses direction with no visible cause; the camera itself pans, zooms, or cuts partway through; the lighting flickers or a shadow jumps abruptly with no visible cause.
level_2: A container or tablet shows an unphysical structural break (e.g., a container cracks or a tablet fractures with no visible cause); the water flow snaps from smooth to turbulent (or vice versa) without a gradual transition; a tablet's position jumps by more than about a quarter of the container's width without any visible drifting motion leading up to it.
level_3: Both containers stay rigid, stationary, and in the same orientation throughout; the water flows smoothly and continuously in both containers; each tablet stays fixed at its placement position without drifting sideways, floating upward, or rotating; the overall scene lighting stays steady across the clip rather than changing abruptly.
level_4: Everything above holds, and: the water level in both containers stays at the same height throughout; the inlet/outlet tubing sits at the same relative spot on each container; the two containers appear at the same depth in frame, with neither one appearing to shift closer to or farther from the camera than the other.
level_5: Everything above holds, and: the water flow's laminar streaking looks natural and continuous rather than repeating or looping; neither tablet's surface flickers, strobes, or shimmers oddly; the clip shows no visible frame freeze, skip, or stutter, and the containers, tablets, and background stay visually locked together with no perceptible drift between them.