Domain: Healthcare — Pharmacy
Target concept: Difference in Hydration Stability between Film Coating and Sugar Coating

Video generation prompt: Two identical transparent beakers containing still distilled water are placed side by side. A film-coated tablet is placed in the left beaker, and a sugar-coated tablet is placed in the right beaker. The appearance and disintegration process are observed.

Evaluation guide:
(i) Target concept: Differential hydration-driven disintegration kinetics between polymeric film coatings and crystalline sugar coatings in aqueous medium.
Minimum mechanism: Sugar coating must be hygroscopic and mechanically weak upon water contact, allowing water to penetrate quickly and granules to shed from the tablet surface; film coating must form a cohesive, mechanically tough polymer layer that hydrates and swells only slowly, so it keeps its structural integrity over the observation window even though it is not necessarily water-repellent.
(ii)Storyline: Frame 0–1s: Two identical beakers filled with still distilled water, side-by-side, both empty; film tablet held above left beaker, sugar tablet above right beaker. Frame 1–2s: Both tablets placed simultaneously into respective beakers and sink to base. Frame 2–10s: Sugar tablet exhibits progressive surface disruption (granules detaching, local turbidity expanding upward); film tablet remains geometrically and optically unchanged: no boundary softening, no clouding, no particle generation. Perspective: Fixed frontal/overhead view capturing full height of both beakers and full lateral span; no occlusion; lighting enables unambiguous discrimination of surface texture and dispersion phenomena.

Manual:
Experimental Procedure
1. Place two identical transparent beakers side-by-side on a flat surface.
2. Fill both beakers with still distilled water to identical levels.
3. Simultaneously place one film-coated tablet in the left beaker and one sugar-coated tablet in the right beaker.
Observation of Experimental Phenomena
- Sugar-coated tablet undergoes visible surface disintegration (granule shedding, cloudiness, particle dispersion) while film-coated tablet remains fully intact (no erosion, no clouding, no shape change).
- Disintegration begins earlier and progresses continuously in the sugar-coated tablet; film-coated tablet shows zero state change throughout.
Summary of Experimental Principles
Film coating (e.g., ethylcellulose) forms a cohesive, slowly hydrating polymer film that resists rapid water ingress and delays disintegration, keeping the tablet intact over the observation period; sugar coating (e.g., sucrose-based) is highly hygroscopic and water-soluble, rapidly absorbing water and undergoing immediate surface breakdown, granule shedding, and disintegration.

Prompt Grounding rubric:
level_1: Two transparent beakers are not both visible, or the liquid in them is not still distilled water (e.g., beakers empty, liquid colored, or liquid absent); no tablet is visible in either beaker, or the tablets present are not one film-coated and one sugar-coated (e.g., both uncoated, both enteric-coated, or both gelatin capsules); the beaker holding the film-coated tablet and the beaker holding the sugar-coated tablet are arranged front-to-back, diagonally, or stacked rather than left-right, so neither beaker can be identified as strictly the left one or the right one; the camera does not hold a single fixed frontal or overhead angle showing both beakers at once.
level_2: Two transparent beakers are visible and roughly left-right of each other, holding liquid, but the liquid is visibly cloudy, tinted, or full of bubbles rather than clear still water; a tablet sits in at least one beaker but its coating cannot be told apart as film versus sugar from surface texture or color; the film-coated tablet and the sugar-coated tablet are placed into their beakers at visibly different moments (e.g., a hand places one tablet in one frame and the other tablet only several frames later).
level_3: Two transparent beakers, each filled with still, clear distilled water, sit with the film-coated tablet's beaker on the left and the sugar-coated tablet's beaker on the right; both tablets are fully submerged and resting motionless on the beaker bottom at the start of the video; no hands, labels, droppers, or other extraneous objects are in frame; a single fixed frontal or overhead camera angle keeps both beakers fully visible for the entire video.
level_4: Everything required for a 3-point video is present, AND the film-coated tablet and sugar-coated tablet are clearly distinguishable at a glance: the film-coated tablet shows a smooth, glossy, uniformly thin coating, while the sugar-coated tablet shows a matte, granular, visibly thicker and slightly irregular coating; the tablets are not swapped between beakers (film-coated tablet stays in the left beaker, sugar-coated tablet stays in the right beaker); glare, reflection, or camera angle never blocks either tablet or beaker base from view.
level_5: Everything required for a 4-point video is present, AND at the moment both tablets are first submerged they still look fully intact and visually indistinguishable from freshly coated tablets, with no premature cracking, softening, or clouding before disintegration would be expected to start; no motion blur obscures either tablet's surface texture at any point; no lighting flare or glare hides either tablet's coating characteristics; both beakers keep the same water level and meniscus shape throughout; the camera never reframes, zooms, or shifts perspective between the two beakers.

Scientific and Causal Correctness rubric:
level_1: No visible difference appears in how the two tablets respond to the water: both the film-coated and sugar-coated tablets break apart fully within the first 3 seconds, or neither shows any visible change for the whole video, or the film-coated tablet disintegrates before the sugar-coated tablet does; alternatively, either tablet fully dissolves into clear water leaving no visible fragments, granules, or cloudiness (dissolution rather than the expected disintegration).
level_2: Visible surface change appears in only one beaker with no corresponding change ever appearing in the other; or granule shedding/cloudiness begins around the sugar-coated tablet but stops or freezes before spreading further; or both tablets end up showing identical cloudiness or fragmentation, erasing the expected contrast; or either tablet's surface swells or cracks but no granules ever detach or disperse into the water afterward.
level_3: The sugar-coated tablet visibly disintegrates (surface erosion, granules shedding into the water, a spreading cloudy halo, or particles dispersing) while the film-coated tablet stays fully intact (no erosion, no shedding, no cloudiness, no change in shape); the sugar-coated tablet begins changing state clearly before the film-coated tablet shows any alteration at all.
level_4: Everything described for score 3 is present, AND the sugar-coated tablet's disintegration keeps building through the video (the cloudy zone keeps expanding, more granules keep detaching, or the halo of dispersed particles keeps growing) while the film-coated tablet shows zero change of any kind (no color shift, no change in opacity, no softening of its outline, no bubbles clinging to its surface); the sugar-coated tablet's disintegration never reverses or re-forms into a solid mass.
level_5: Everything described for score 4 is present, AND the film-coated tablet keeps a sharp, well-defined outline and even surface shine for the entire video; the sugar-coated tablet's breakdown stays confined to its outer layers, never splitting open or exposing a solid core; no granules or cloudiness from the sugar-coated tablet's beaker cross over into the film-coated tablet's beaker; neither tablet shows behavior inconsistent with its density, such as unexpected floating, bubbling, or abnormally fast sinking.

Spatiotemporal Consistency rubric:
level_1: The video cuts to a new camera angle or shot partway through the recording; the water level or a tablet's state resets to how it looked earlier after already having progressed (e.g., the sugar-coated tablet's granule halo shrinks back down or disappears and then reappears); the room lighting switches abruptly from one setup to another (e.g., soft ambient light suddenly replaced by a harsh spotlight) partway through; either beaker's apparent size or shape changes noticeably between frames (e.g., the right beaker suddenly looks taller or narrower with no camera movement to explain it).
level_2: The gap between the left and right beakers visibly narrows or widens between frames even though the camera itself does not move; the film-coated tablet appears to rotate or tip over inside its beaker with no current or disturbance to explain it; the water's meniscus in either beaker flips between flat and curved from one frame to the next with no cause; the shadow cast by either beaker swings to point in a different direction partway through the video; the overhead lighting brightens or dims enough that the sugar-coated tablet's granular texture becomes hard to tell apart from the film-coated tablet's smooth texture.
level_3: The left and right beakers stay in the same spot and orientation for the whole video; the film-coated tablet and the sugar-coated tablet (or its remaining solid portion) each stay resting inside their own beaker without drifting toward the glass wall or out of frame; the water in both beakers stays visually flat and undisturbed except for motion directly caused by the sugar-coated tablet's own disintegration; the room lighting neither strobes, dims, nor brightens across the recording, and each beaker casts one shadow that keeps a constant direction and darkness the whole time; neither beaker is cut off by the frame edge.
level_4: Everything present in the 3-point description holds, AND the gap between the two beakers stays constant throughout, with no camera tilt that makes one beaker look bigger or closer than the other; the film-coated tablet stays near the center of the left beaker's base and the sugar-coated tablet (or its dispersing granules) stays near the center of the right beaker's base; neither beaker visibly shakes or slides even slightly between frames.
level_5: Everything present in the 4-point description holds, AND the recording shows no dropped frames, repeated frames, or stutter in motion, and no cut in time; the water in both beakers stays visibly still apart from motion the sugar-coated tablet's disintegration itself causes; both beakers and whatever remains of each tablet keep a constant apparent size and sharpness throughout, with no zooming, refocusing, or depth-of-field change altering how clearly either tablet can be seen.