Domain: Healthcare — Pharmacy
Target concept: Release differences of enteric coating under different pH environments

Video generation prompt: Two identical transparent beakers are placed side by side. The left beaker is filled with an acidic solution (pH=1.2), and the right beaker is filled with a neutral solution (pH=7.4). Identical enteric-coated tablets are placed into both beakers, and the setup is left undisturbed for observation.

Evaluation guide:
(i) Target concept: pH-dependent solubility of enteric coating polymers.
Minimum mechanism: Coating must remain physically intact in acidic medium due to protonated, hydrophobic polymer chains; in neutral medium, deprotonation increases hydrophilicity and water penetration, enabling erosion, observable as surface degradation without bulk disintegration.
(ii)Storyline: Frame 0–1: Static wide shot showing two identical transparent beakers side-by-side, both empty. Frame 1–2: Acidic solution poured into left beaker; neutral solution poured into right beaker (liquids appear clear and colorless). Frame 2–3: Two identical enteric-coated tablets placed simultaneously, one into each beaker, fully submerged. Frame 3–10: Continuous still observation: left tablet remains optically unchanged; right tablet develops progressive, localized surface disruption (pitting/cloudiness) confined to immediate periphery: no detachment, no dissolution in left, no stability in right. Viewpoint is fixed frontal, full-beaker framing, no cuts or zooms.

Manual:
Experimental Procedure
1. Place two identical transparent beakers side-by-side.
2. Fill left beaker with acidic solution (pH=1.2); fill right beaker with neutral solution (pH=7.4).
3. Simultaneously place one identical enteric-coated tablet into each beaker.
4. Observe undisturbed for 10 seconds.
Observation of Experimental Phenomena
In left beaker (pH=1.2): tablet coating remains fully intact, no erosion, no cloudiness, no particle release.
In right beaker (pH=7.4): tablet coating shows visible surface erosion, pitting, or localized cloudiness around tablet; no such change in left beaker.
Summary of Experimental Principles
Enteric coatings are polymers insoluble in gastric acid (pH 1–3) but soluble in intestinal neutral-to-alkaline environments (pH ≥ 5.5); thus, they resist dissolution in pH=1.2 but degrade in pH=7.4.

Prompt Grounding rubric:
level_1: The scene never shows two identical transparent beakers standing side by side with an enteric-coated tablet placed in each; or the left beaker is never shown holding the acidic (pH 1.2) solution and the right beaker the neutral (pH 7.4) solution; or the two tablets are not placed into their separate beakers via one simultaneous action or two clearly sequential drops.
level_2: Two transparent beakers side by side are shown, but at least one setup element is wrong or missing: the two liquids are not clearly poured as two separate fillings (e.g., only one beaker is filled, or liquid is added to just one beaker), the two tablets are not visibly identical enteric-coated tablets, or a tablet is dropped in a way (from far above, at a steep angle, off-frame) that leaves it unclear which beaker it landed in.
level_3: Two identically shaped transparent beakers stand side by side, each holding a clear, colorless liquid; one identical enteric-coated tablet is fully submerged in each beaker; both tablets are placed via one continuous action or two visibly sequential single drops, one per beaker; no tablet is swapped for a different dosage form (e.g., capsule, loose powder) and no beaker is swapped for an opaque or colored vessel.
level_4: Everything in the 3-point description holds, and additionally: both liquids stay clear and colorless right after the tablets are added (no artificial coloring is used to visually flag 'acidic' vs. 'neutral'), each tablet's coating looks smooth and unbroken at the moment it settles in the liquid, and the camera holds one fixed, front-on framing that keeps both full beakers in view without cropping either one.
level_5: Everything in the 4-point description holds, and additionally: the two beakers match each other in height, width, and liquid fill level to the eye; the two tablets rest in the same orientation (e.g., both flat side down); there is no visible compositing artifact: no duplicated tablet, no mismatched reflection between the two beakers, no shadow falling a different way than a single overhead/side light source would produce; and the beakers stay centered and evenly spaced in the frame for the whole shot.

Scientific and Causal Correctness rubric:
level_1: No dissolution difference is shown between the two tablets at all (both look unchanged, or both develop identical surface change); or the pattern is reversed for enteric coating: the pH 1.2 (acidic) tablet's coating visibly erodes while the pH 7.4 (neutral) tablet stays fully intact; or the coating erodes identically and simultaneously in both beakers regardless of pH.
level_2: A coating change appears on at least one tablet, but it does not match how an enteric coating behaves, e.g., surface pitting or cloudiness appears in the acidic (pH 1.2) beaker before or instead of the neutral (pH 7.4) beaker, the acidic-side tablet is the one that visibly erodes, or the neutral-side tablet degrades within the first second with no gradual build-up.
level_3: By the end of the 10-second observation, the acidic (pH 1.2) tablet's coating still looks smooth and intact with no pitting, cloudiness, or shed particles, while the neutral (pH 7.4) tablet shows visible coating erosion, surface pitting, or a halo of cloudiness confined to its own beaker; the acidic-side tablet shows none of this at any point.
level_4: Everything in the 3-point description holds, and additionally: the acidic-beaker tablet shows no erosion or cloudiness in any frame across the 10 seconds, the neutral-beaker tablet's degradation builds up gradually (intact coating first, then visible pitting or cloudiness) rather than vanishing or breaking apart all at once, and no stray particles, bubbles, or lighting artifacts in either beaker could be mistaken for coating fragments.
level_5: Everything in the 4-point description holds, and additionally: the neutral-beaker degradation stays localized to the tablet's own surface, with no coating fragments breaking off and drifting through the liquid; the acidic-beaker tablet and the liquid around it look the same in clarity and appearance from the first frame to the last; and nothing in the scene (no stirring, shaking, added drop, or flash of light) suggests an outside trigger sped up or staged the neutral-side erosion.

Spatiotemporal Consistency rubric:
level_1: A beaker's position, size, or contents changes abruptly between one frame and the next with no visible cause, e.g., a beaker jumps to a different spot on the table, a tablet appears already sitting inside a beaker with no drop or pour ever shown, a liquid's height changes in a sudden jump rather than settling as the tablet enters, or the overall scene lighting suddenly brightens, dims, or shifts color partway through the shot.
level_2: Several smaller continuity breaks occur, e.g., one beaker or tablet briefly disappears and reappears in a later frame, a liquid surface ripples or bobs on its own with no tablet motion or disturbance to explain it, part of a beaker or tablet is blocked from view in some frames and clearly visible again later for no physical reason, or the shadow cast beneath a beaker points a different way in different frames even though neither the camera nor the light source moves.
level_3: Both beakers, both liquids, and both tablets stay visibly present in the same relative positions on screen for the full 10 seconds; neither beaker nor tablet disappears, duplicates, or changes shape; the overall lighting and the direction of any cast shadows stay the same throughout; any settling motion a tablet makes after entering the liquid looks like ordinary sinking rather than floating or jumping.
level_4: Everything in the 3-point description holds, and additionally: once a tablet comes to rest, it stays at the same spot on its beaker's bottom with no unexplained drifting or resurfacing; each liquid surface stays flat and level, without waves or meniscus distortion that would be inconsistent with an undisturbed, still container; and neither beaker nor tablet visibly stretches, jitters, or changes proportion from one frame to the next.
level_5: Everything in the 4-point description holds, and additionally: the outlines of both beakers, both tablets, and both liquid surfaces stay continuously aligned frame to frame with no visible misregistration or drift; the video shows no flicker, strobing, or stuttering at any point; and the front-to-back layering of the two beakers relative to each other and the background stays consistent, with no visible popping or swap in which one appears in front of the other.