Samantha912/NLP_A2_WTH huggingface dataset:
Ornithine aminotransferase (OAT) is an enzyme which is encoded in human by the OAT gene located on chromosome 10.

The OAT involved in the ultimate formation of the non-essential amino acid proline from the amino acid ornithine. Ornithine aminotransferase forms the initial intermediate in this process. It catalyzes the reverse reaction as well, and is therefore essential in creating ornithine from the starting substrate proline.

Structure 
The OAT gene encodes for a protein that is approximately 46 kDa in size. The OAT protein is expressed primarily in the liver and the kidney but also in the brain and the retina. The OAT protein is localized to the mitochondrion within the cells where it is expressed.

The structure of the OAT protein has been resolved using X-ray crystallography and shows similarity to other subgroup 2 aminotransferases such as dialkyglucine decarboxylatse. The OAT protein functions as a dimer and each monomer consists of a large domain, which contributes most to subunit interface, and a C-terminal small domain, and an N-terminal region containing a helix, loop, and three-stranded beta-meander. In the central large domain is a seven-stranded beta-sheet covered by eight helices. The co-factor of the OAT protein (pyridoxal-5'-phosphate) binds to OAT through a Schiff base at the lysine 292 position situated between two of the seven-stranded beta-sheet. Three amino acids (R 180, E 235, and R413) are thought to be involved in substrate binding at the active site.

Function  
Ornithine aminotransferase catalyzes the transfer of the delta-amino group from L-ornithine

 L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid

The reaction requires pyridoxal 5'-phosphate as a co-factor and forms part of the subpathway that synthesizes L-glutamate 5-semialdehyde from L-ornithine.

Clinical significance
Mutations in the OAT gene can lead to malfunctioning proteins, including both point mutations that abolish catalytic activities, large frame-shift mutations, as well as mutated proteins that are not properly targeted to the mitochondrion where its normal functionality occurs. In the latter, abnormality of mitochondrial import causes ectopic accumulation of the OAT protein in the cytosol followed by rapid degradation by proteolysis. Deficiency of OAT activities causes ornithine aminotransferase deficiency, also known as  gyrate atrophy of choroid and retina.

The mechanism of gyrate atrophy of choroid and retina is thought to involve the toxicity of glyoxylate.

See also
 Glutamate-5-semialdehyde

References

External links
 
 

EC 2.6.1
Mitochondrial proteins
Me was Ray Stevens' twentieth studio album and his third and final for Mercury Records, released in 1983. In 1982, Stevens returned briefly to Mercury to record this album (his first for that label in 20 years) before moving to MCA Records in 1984. The front of the album cover shows Stevens portraying a painter painting a self-portrait; while the back shows the finished portrait on a table along with a second self-portrait that is sketched by pencil, a cup filled with paint brushes, the paint tray, tubes of paint, a small glass filled with water and a rose, and a lamp. Two singles were lifted from the album: "Love Will Beat Your Brains Out" (which did not chart) and "My Dad."

Track listing

Personnel 
 Produced by Jerry Kennedy and Ray Stevens
 Arranged by Ray Stevens
 Engineer – Stuart Keathley
 Recorded and Mixed at Ray Stevens Studio (Nashville, Tennessee).
 Mastered by Randy Kling at Disc Mastering, Inc. (Nashville, Tennessee).
 Photography – Slick Lawson
 Paintings and Sketches – Susan Scott

Musicians
 Ray Stevens – vocals, other synthesizers 
 Rodger Morris – acoustic piano, Rhodes piano, Gleemon synthesizer 
 Mark Casstevens – acoustic guitars 
 John Clausi – electric guitars 
 Steve Gibson – electric guitars 
 Weldon Myrick – dobro, steel guitar
 Jack Williams – bass
 Jerry Carrigan – drums  (1, 3-10)
 James Stroud – drums (2)
 Terry McMillan – percussion, harmonica, Jew's harp
 Nashville String Machine – strings 
 Suzi Ragsdale – backing vocals (1), female vocal (7)
 The Cherry Sisters (Sheri Huffman, Lisa Silver and Diane Tidwell) – backing vocals 
 Alan Moore – backing vocals 
 Hurshel Wiginton – backing vocals

Chart performance

Singles

References

1983 albums
Ray Stevens albums
Mercury Records albums
Victor Henry Naismith (1 May 1936 – 26 October 2021) was an Australian rules footballer who played with Richmond in the Victorian Football League (VFL). 

A talented sportsman at tennis, squash, golf and throwing events, Naismith was in contention to compete in the javelin at the 1956 Melbourne Olympics, but injured his shoulder at work. He did however represent the VFL/VFA team in the Australian football exhibition match at the Games.

Notes

External links 		
		
		
		
		
		
		
1936 births
2021 deaths
Australian rules footballers from Victoria (state)		
Richmond Football Club players
Oakleigh Football Club players
"Paper Planes" is the debut single by season six runner-up of The Voice Australia, Hoseah Partsch. It is co-written by Dennis Dowlut (ex-Disco Montego) and Maxwell Bidstrup, which was released digitally immediately after the final on 2 July 2017. The song debuted and peaked at number 35 on the ARIA Singles Chart with 5,147 sales.

Speaking about the single, Partsch said: "I fell in love with it straightaway... It feels like something that I would have written myself. It talks about my life and things that I'm going through today. I've been blessed, and I feel like I'm flying. I'm extremely excited about everything that’s coming up. I can't wait."

A lyric music video was released on YouTube on 7 December 2017.

On the 8 February 2018, Partsch performed the song live on BBC Radio 2 breakfast show.

Versions 
 Original – 3:44 
 MOZA remix – 3:18 
 Hounded remix – 3:14 
 Haides remix – 4:21 
 Cuurely remix – 3:43

Charts

Release history

References 
 

2017 songs
2017 debut singles
Universal Records singles
There were six badminton events at the 2018 South American Games. The events were held from 26 May to 31 May at the Evo Morales Coliseum in Cochabamba, Bolivia.

Medal table
The table below gives an overview of the medal standings of badminton events at the 2018 South American Games.

Medalists
The table below gives an overview of the medal winners of badminton events at the 2018 South American Games.

Results

Men
Final four

Top half

Bottom Half

Men's doubles

Women

Women's doubles

Mixed doubles

References

External links
 Tournament results at www.cochabamba2018.bo

Badminton
South American Games
2018
A Parish Centre of Worship is a church or other building licensed as such by the diocesan bishop in the Church of England, usually where there is no parish church. For most purposes it is deemed to be a parish church but it is dedicated, not consecrated, and parishioners have a right to be married in any neighbouring parish.

References

Types of church buildings
Brown's Ferry Park is a  park in the Clackamas County portion of the city of Tualatin in the U.S. state of Oregon. The park is located along the Tualatin River.

It is named for  Zenas J. Brown who operated the first ferry in the Tualatin area, and who claimed land at this location in 1850 through the Donation Land Act.

The park includes walking paths, picnic tables, kayak and canoe rentals and a canoe ramp and dock, a wildlife viewing blind, a river overlook platform, and an old barn with interpretative signage.

References

External links

Canoeing at Brown's Ferry Park

Tualatin, Oregon
Municipal parks in Oregon
Parks in Clackamas County, Oregon
Sphaerocardamum is a genus of flowering plants belonging to the family Brassicaceae.

Its native range is Northeastern Mexico.

Species:

Sphaerocardamum compressum 
Sphaerocardamum divaricatum 
Sphaerocardamum macrum 
Sphaerocardamum nesliiforme 
Sphaerocardamum stellatum

References

Brassicaceae
Brassicaceae genera
Cormac Ó Domhnalláin, Ollamh Síol Muireadaigh, died 1436.

The Annals of Connacht state:

1436:Cormac O Domnallain, ollav of the Sil Murray in Poetry, died.

Sources

The Encyclopaedia of Ireland 2003; .
 Mac Dermot of Moylurg: The Story of a Connacht Family Dermot Mac Dermot, 1996.
A New History of Ireland VIII: A Chronology of Irish History to 1976 - A Companion to Irish History Part I edited by T.W. Moody, F.X. Martin and F.J. Byrne, 1982. 
The Celebrated Antiquary Nollaig O Muralie, Maynooth, 1996.
Irish Leaders and Learning Through the Ages Fr. Paul Walsh, 2004. (ed. Nollaig O Muralie).

External links
List of Published Texts at CELT — University College Cork's Corpus of Electronic Texts

1436 deaths
14th-century Irish historians
People from County Galway
People from County Roscommon
15th-century Irish poets
Irish-language writers
Year of birth unknown
Irish male poets
"Each Small Candle" is a song by Roger Waters. The song was premiered as part of In the Flesh tour and subsequently released on the live album In the Flesh – Live in 2000. No studio version of the song has been released.

During the In the Flesh tour "Each Small Candle" was included in the encore of all the concerts of the 2000, and some of the concerts of the 2002 tour (alternating with "Flickering Flame", another new song).

Most of the lyrics were inspired by a news story from the Kosovo war of a Serbian soldier who saw a wounded Albanian woman, left his ranks and helped her.

References

 Each Small Candle on RogerWaters.com - included reference to the "South American man who had been tortured".
 Who is Who - claim about the real story behind Each Small Candle

2000 songs
Roger Waters songs
Songs written by Roger Waters
Song recordings produced by Roger Waters
Rock ballads
Antti Veikko Ilmari Siltavuori (29 October 1926 – 9 March 2012), better known as Jammu Siltavuori or Jammu-setä ("Uncle Jammu"), was a Finnish murderer and sexual offender.

Early life
Veikko Siltavuori was born in Vaasa, Finland. Information about his early life is very limited. According to some sources his childhood was very hard and complicated, because of his alcoholic father who beat Veikko very much. He was bullied in school and he was called a weasel because of his dirty clothing.

Crimes
Siltavuori became well known in Finland when he murdered two eight-year-old girls, Päivi-Maria Hopiavuori and Tanja Johanna Pirinen in 1989. He burned the bodies shortly after. He had picked up both girls into his car from Myllypuro, a neighbourhood in Helsinki, on 3 March 1989. Prior to this, he had been convicted of raping a five-year-old girl, sexual harassment, and attempted murder. He had previously been sentenced to life imprisonment in the 1960s, but was later paroled. He had also built a jail complete with cells, barred windows and small toilets in Paltamo, Kainuu.

Media publicity
The murders led to widespread media publicity, during which hundreds of letters to the editor were written about Siltavuori. An interview with Siltavuori was published in the April 1991 issue of Rikosposti, in which he said that he was the most hated person in Finland. There were demands for the death penalty or castration for him.

Antti Siltavuori, an industrial designer from Kirkkonummi, was the target of a telephone terror because of his name, and an old man was beaten in a restaurant in Helsinki because he resembled Jammu in appearance. The protesters' signs read, among other things: "A sex offender does not get better in prison. Experts in favor of involuntary treatment."

Sentences
For the two murders in 1989, Veikko Siltavuori was sentenced to 15 years in prison with the possibility of parole after 10 years, because a mental health examination legally found him to be partially insane. If that had not been the case, Siltavuori would have been again sentenced to life imprisonment.

After 10 years elapsed, his first and second parole hearings in a Prison Court were unsuccessful. After he served one more year in jail, the Prison Court released him on strictly supervised parole on 31 January 2000, on his third parole hearing. However, he was immediately involuntary committed to the Niuvanniemi mental hospital in Kuopio for criminal-psychiatric reasons. The involuntary commitment was reaffirmed in 2007 by the administrative court of Kuopio, on the basis that if he was released, he would be a serious security risk.

Death
While imprisoned, Siltavuori was attacked by another inmate, which caused Siltavuori to spend his final years in a wheelchair. He died in March 2012 at the age of 85 in Kuopio.

References

Literature
 Markkula, Hannes: Kuusi suomalaista murhaa. 1996.

1926 births
2012 deaths
20th-century Finnish criminals
Finnish male criminals
People from Vaasa
Finnish murderers of children
Finnish people convicted of murder
People convicted of murder by Finland
People convicted of child sexual abuse
Violence against women in Finland
Osleivis José Basabe Chourio (born September 13, 2000) is a Venezuelan professional baseball infielder for the Tampa Bay Rays of Major League Baseball (MLB). He made his MLB debut in 2023.

Career

Texas Rangers
On December 23, 2017, Basabe signed with the Texas Rangers as an international free agent. He made his professional debut in 2018 with the Dominican Summer League Rangers, hitting .344/.414/.474 with 1 home run, 34 RBI, and 12 stolen bases. He split the 2019 season between the rookie–level Arizona League Rangers and Low–A Spokane Indians, hitting a combined .323.352/.398 with 32 RBI. Basabe did not play in a game in 2020 due to the cancellation of the minor league season because of the COVID-19 pandemic.

Tampa Bay Rays
On December 10, 2020, the Rangers traded Basabe, Heriberto Hernandez, and Alexander Ovalles to the Tampa Bay Rays in exchange for Nathaniel Lowe, Jake Guenther, and Carl Chester. He split his first season in the Rays organization between the Charleston RiverDogs and Bowling Green Hot Rods, hitting .282/.347/.388/.734 with 3 home runs, 36 RBI, and 18 stolen bases. Basabe split the 2022 campaign between Bowling Green and the Montgomery Biscuits, hitting a combined .324/.385/.462/.847 with 4 home runs, 47 RBI, and 21 stolen bases.

On November 15, 2022, the Rays added Basabe to their 40-man roster to protect him from the Rule 5 draft. Basabe was optioned to the Triple-A Durham Bulls to begin the 2023 season. On August 13, Basabe was promoted to the major league for the first time. Basabe hit his first career home run, a grand slam against the Colorado Rockies, on August 22, 2023.

Personal life
Basabe's cousin, Luis Matos, is currently an outfielder for the San Francisco Giants. Another cousin, Luis Alexander Basabe, previously played in Major League Baseball (MLB) for the Giants. Another cousin, Luis Alejandro Basabe, is also a professional baseball player.

References

External links

2000 births
Living people
Sportspeople from Miranda (state)
Venezuelan expatriate baseball players in the United States
Major League Baseball players from Venezuela
Major League Baseball infielders
Tampa Bay Rays players
Águilas del Zulia players
Dominican Summer League Rangers players
Arizona League Rangers players
Spokane Indians players
Charleston RiverDogs players
Bowling Green Hot Rods players
Montgomery Biscuits players
Durham Bulls players
A megaplex is a movie theater complex with many screens.

Megaplex may also refer to:
 Megaplex (album), an album by We Are Scientists
 Megaplex (convention), a furry convention held annually in Orlando, Florida
 Megaplex (General Jean Victor Allard Building), a building in Saint-Jean-sur-Richelieu, Quebec
 Megaplex Theatres, a chain of movie theaters in Sandy, Utah
 Virgin Megaplex, a movie theater chain in the United Kingdom
 A Win32 clone of Supaplex, itself a clone of Boulder Dash

See also
 Boston Sports Megaplex, a failed proposal for a sports complex in Boston
Scott Bryan is an American chef. He has served as the executive chef of Veritas and Apiary in New York City. Veritas received three stars from The New York Times when Bryan was a chef there. In his 2000 memoir Kitchen Confidential, Anthony Bourdain referred to Bryan as "a cult figure among cooks".

Early life
Bryan was born in Brookline, Massachusetts. He attended Brookline High School. After graduation, he enrolled in Johnson & Wales University's College of Culinary Arts. He dropped out of school to work for Robert Kinkead at Harvest in Cambridge, Massachusetts. After moving to France, he returned to the US and worked at 21 Federal in Nantucket, Massachusetts for a time. He then worked as sous chef under Éric Ripert at Le Bernardin. His first position as executive chef was at Luma in 1994, then a vegetarian restaurant. Bryan reworked the menu to include meat and turned the struggling restaurant around. He then moved to Indigo which he started with business partner Gino Diaferia. After serving as executive chef at Indigo for four years, he and Diaferia opened Veritas in 1999. While at Veritas, Bryan received a three star rating from The New York Times. He finally left Veritas in 2007 to work at 10 Downing Street, but due to delays left the project and became executive chef at Apiary instead. He left Apiary in 2014 and served as executive chef at The Milling Room until January 2018.

Awards and honors
1996 America's Best New Chef from Food & Wine

References

Year of birth missing (living people)
Living people
Brookline High School alumni
Johnson & Wales University alumni
American male chefs
Chefs from Massachusetts
People from Brookline, Massachusetts
is a Japanese television jidaigeki or period drama that was broadcast in 1986. It is the 26th in the Hissatsu series. Inspired by Video game Super Mario Bros.

Cast 
 Kunihiko Mitamura as Hide
 Yoko Akino as Keima no Ogin
 Shōfukutei Tsurube II as Ayamaro
 Teruhiko Saigō as Toukichi
 Mikio Osawa as Sabu
 Masako Sugawara as Wakamurasaki
 Gorō Mutsumi as Kagurazaka Soemon
 Jūkei Fujioka as Mukojima Jinjurō

References

1986 Japanese television series debuts
1980s drama television series
Jidaigeki television series
Thomas Crowley Weston  (born 1958) is a New Zealand lawyer and former Chief Justice of the Cook Islands. He is also known as a poet.

Biography
Weston was born in 1958 in Christchurch. He attended the University of Canterbury, from where he graduated with LL.B. (Hons).

Weston has a long history as a commercial litigator.  He was appointed Queen's Counsel in 1999, and later that year was appointed to the Rules Committee, the body responsible for setting court rules. He was reappointed in 2002 for a further term of three years.

From 2006, was a part-time judge of the Cook Islands High Court and Court of Appeal.  Between 2010 and 2016, he was  Chief Justice of the Cook Islands, replacing his legal partner David Williams.

Weston has published several books of poems. Small Humours of Daylight deals mostly with travel by sea between islands, and was reviewed by Graham Brazier for The New Zealand Herald.

Bibliography

Poetry collections
Too Lost to Land (multiple authors) 
The Red Orchestra
The Ambiguous Companion
Naming the Mind Like Trees
Small Humours of Daylight
Only One Question

Books on law
Taking Control: A Seminar on Loss Prevention and Risk Management (co-author)
Competition Law Update (co-author)
Competition Law: Must Knows (co-author)

References

External links
 Tom Weston QC at Bankside Chambers.

Living people
1958 births
Chief justices of the Cook Islands
New Zealand judges on the courts of the Cook Islands
New Zealand King's Counsel
New Zealand poets
New Zealand male poets
People from Christchurch
University of Canterbury alumni
Tom
Legitimate peripheral participation (LPP) describes how newcomers become experienced members and eventually old timers of a community of practice or collaborative project . LPP identifies learning as a contextual social phenomenon, achieved through participation in a community practice. According to LPP, newcomers become members of a community initially by participating in simple and low-risk tasks that are nonetheless productive and necessary and further the goals of the community. Through peripheral activities, novices become acquainted with the tasks, vocabulary, and organizing principles of the community's practitioners.

Gradually, as newcomers become old timers and gain a recognized level of mastery, their participation takes forms that are more and more central to the functioning of the community. LPP suggests that membership in a community of practice is mediated by the possible forms of participation to which newcomers have access, both physically and socially. In the case of a mentor-mentee relationship between older timers and newcomers, the old timer has both the power to confer legitimacy to the newcomer, and to control the newcomer's level of access to different community practices and experiences. If newcomers can directly observe the practices of experts, they understand the broader context into which their own efforts fit. Conversely LPP suggests that newcomers who are separated from the experts have limited access to their tools and community and therefore have limited growth. As participation increases, situations arise that allow the participant to assess how well they are contributing through their efforts, thus legitimate peripheral participation provides a means for self-evaluation .

LPP is not reserved for descriptions of membership in formal organizations or professions whose practices are highly defined. For example, O'Donovan and Kirk  suggest that young people's participation in sport can be compared to a Community of Practice related to physical education.

In his later work  on communities of practice, Wenger abandoned the concept of legitimate peripheral participation and introduced the idea of a duality instead; however, the term is still widely used in relation to situated learning.

See also
 Community of practice
 Cultural-historical activity theory (CHAT)
 Knowledge sharing
 Online participation

References

Further reading
 Bryant, Susan, Andrea Forte and Amy Bruckman, Becoming Wikipedian: Transformation of participation in a collaborative online encyclopedia, Proceedings of GROUP International Conference on Supporting Group Work, 2005. pp 1.-10 

Educational psychology
Sociology of education
Maurice Bernachon (born in Saint-André-le-Gaz, July 1919; died in Lyon in the night from 17 to 18 September 1999) was a master chocolatier and founder of the Bernachon family business.

Biography 
The son of a signalman, Bernachon started an apprenticeship as pâtissier in Pont-de-Beauvoisin at 12 years of age. In 1975 he created the Président, a cake creation to celebrate the admission to the French League of Honor of Paul Bocuse by then-president of France Valéry Giscard d'Estainga cake that made him famous.

He was one of the few French chocolatiers who would entirely manufacture their own chocolate from raw cocoa, imported variously from Venezuela, Colombia, Brazil and Equatorial Guinea.

He retired in 1997, leaving the management of his chocolate business to his son Jean-Jacques (1944-2010), husband to Françoise, the daughter of Paul Bocuse.

The business is currently run by Philippe and Stéphanie Bernachon, the children of Françoise and Jean-Jacques.

Bibliography 
Bernachon, Maurice & Bernachon, Jean-Jacques (1985) La passion du chocolat. Flammarion. 117 pages. Google books identifier e9z2AAAACAAJ. Accessed on 10 August 2014.
Deligeorges, Stéphane (2009) Le chocolat selon Bernachon. Glénat. 246 pages. Google books identifier tniQgAACAAJ. . Accessed on 10 August 2014.

References 

Chocolatiers
Florence A. Reuter (born 20 December 1969) is a Belgian Reformist politician who is currently the Mayor of Waterloo.

Political career 
The 6 March 2015, she was sworn in and became mayor of Waterloo, following the resignation of Serge Kubla and his indictment for corruption.

References 

1969 births
Living people
Reformist Movement politicians
21st-century Belgian politicians
21st-century Belgian women politicians
Vrije Universiteit Brussel alumni
21st-century Belgian journalists
Mayors of places in Belgium
Women mayors of places in Belgium