Samantha912/NLP_A2_WTH huggingface dataset:
Squaraine dyes are a class of organic dyes showing intense fluorescence, typically in the red and near infrared region (absorption maxima are found between 630 and 670 nm and their emission maxima are between 650–700 nm). They are characterized by their unique aromatic four membered ring system derived from squaric acid. Most squaraines are encumbered by nucleophilic attack of the central four membered ring, which is highly electron deficient. This encumbrance can be attenuated by the formation of a rotaxane around the dye to protect it from nucleophiles. They are currently used as sensors for ions and have recently, with the advent of protected squaraine derivatives, been exploited in biomedical imaging.

Synthesis
Synthesis of squaraine dyes was reported at least in 1966. They are derived from squaric acid which undergoes an electrophilic aromatic substitution reaction with an aniline or another electron rich derivative to form a highly conjugated product with extensive charge distribution. 
For instance, squaraine dyes are also formed via reaction of squaric acid or its derivatives with so-called "methylene bases" like 2-methyl-indolenines, 2-methyl-benzthiazoles or 2-methyl-benzo-selenazoles. Indolenine-based squaraines combine good photostability including high quantum yields when bound to proteins and reactive versions of these dyes are commonly used as fluorescent probes and labels for biomedical applications.

Squarylium dye III

Squarylium dyes have poor solubility in most solvents, except for dichloromethane and a few others. Their absorption peaks at ~630 nm and luminescence at ~650 nm. The luminescence is photochemically stable  and its quantum yield is ~0.65.

Squarylium dye molecules can be encapsulated into carbon nanotubes enhancing the optical properties of carbon nanotubes. Efficient energy transfer occurs between the encapsulated dye and nanotube — light is absorbed by the dye and without significant loss is transferred to the nanotubes. Encapsulation increases chemical and thermal stability of squarylium molecules; it also allows their isolation and individual characterization. For example, encapsulation of dye molecules inside carbon nanotubes completely quenches strong dye luminescence, thus allowing measurement and analysis of their Raman spectra.

See also
Squaric acid

References 

Fluorescent dyes
Cyclobutenes
Sphereland: A Fantasy About Curved Spaces and an Expanding Universe is a 1965 translation of , a 1957 novel by Dionys Burger, and is a sequel to Flatland, a novel by "A Square" (a pen name of Edwin Abbott Abbott). The novel expands upon the social and mathematical foundations on which Flatland is based. It is markedly different from the first novel in that it has a more prosaic ending and treatment of society.

Plot summary
The Circles (who are appointed as priests/leaders of Flatland due to their many sides, or an appearance thereof) do not take A Square's revelation about a third dimension to be accurate, and A Square is ostracized by his community. Then after some time, society becomes more open to the ideas of Spaceland and, overall, to change and advancement. However, when a prominent surveyor finds a Triangle with more than 180 degrees, he is fired from his job and generally considered a crackpot, since such a construction is not possible in Euclidean geometry. He eventually makes friends with the grandson of A Square, A Hexagon, because he is a mathematician and scientist. Together, they come upon a theory to explain the unusual measurements: they actually live on a very large sphere, and the Triangles have more than 180 degrees due to being inscribed on a non-planar surface.

With help from the sphere from the first novel, they are able to prove this theory. However, the established scientific community is not able to comprehend the idea proposed by the two, and thus they do not attempt to enlighten Flatland. Furthermore, as the residents of Flatland advance, they begin to travel in space; they see distant worlds like their own, and the surveyor tries to find the distance between their world and these distant worlds, using trigonometry and radar. From his calculations, he and the hexagon determine that the universe is expanding; again they try to reveal this theory to the outside world, but again it is not accepted. Therefore, like his grandfather in the previous novel, the hexagon writes a book that is not to be opened until the theory of the expanding universe is discovered and accepted by others. Then they live an inferior existence without any more contact with the sphere.

Adaptations and parodies
In 2012 the creators of Flatland: The Movie released an educational sequel film, Flatland 2: Sphereland based in part on Burger's Sphereland that dealt with the topics of curved spaces, symmetry and congruence, an expanding universe, and the multiverse.  Actors Kristen Bell, Danny Pudi, Michael York, Tony Hale, Danica McKellar, and Kate Mulgrew provide voices for the 36-minute animated movie.

See also

 Fourth dimension
 Flatterland, another sequel to Flatland

References

1965 novels
1965 science fiction novels
Dutch novels adapted into films
Fictional dimensions
Novels about mathematics
Sequel novels
Loring International Airport is the operational name of the airfield at the former Loring Air Force Base in Limestone, Maine, United States. It is currently (as of August 2022) operated by the Loring Commerce Centre. The airfield itself sits on 1,600 acres of land and is kept in good condition.

The Loring Air Force Base Arch Hangar is a hangar constructed by the United States Air Force as part of Loring Air Force Base. It was constructed at the same time as the base's double cantilever hangar. The arch hangar was the largest monolithic arch structure in the United States at the time of its completion.

See also
 List of airports in Maine

References

External links

Airports in Aroostook County, Maine
Limestone, Maine
Loring Air Force Base
Anambah is a locality in the City of Maitland region of New South Wales. It had a population of 30 as of the .

It is scheduled for suburban development in future as a continuation of the Maitland growth corridor.

Notable People 

 Henry Luke White born there in 1860.

Heritage listings
Anambah has a number of heritage-listed sites, including:
 Anambah Road: Anambah House

References

Localities in New South Wales
City of Maitland
NBC 22 may refer to one of the following television stations in the United States:

Current
WLWK-CD in Sturgeon Bay, Wisconsin
Translator of WGBA-TV in Green Bay, Wisconsin
WWLP in Springfield, Massachusetts

Former
KFSA-TV (now KFSM-TV on channel 5) in Fort Smith, Arkansas (1953 to 1958)
WJCL in Savannah, Georgia (1982 to 1985)
WKEF in Dayton, Ohio (1980 to 2004)
J. Michael Ruane (December 10, 1927, in Salem, Massachusetts – June 25, 2006, in Danvers, Massachusetts) was an American politician who represented the 7th Essex district in the Massachusetts House of Representatives from 1975 to 2005.

Early career
The son of a grocery store manager, Ruane attended St. Mary's Boys High School in Lynn, Massachusetts. After graduation he spent three years as a member of the United States Navy. After his military service, Ruane returned to Salem, where he worked for the city as a clerk in the motor division and as a coach, basketball referee and baseball umpire for the Recreation Department. He served as a councilor-at-large on the Salem City Council from 1970 to 1975.

House of Representatives
Ruane was elected to the Massachusetts House of Representatives in 1974. As a result of redistricting, he faced, and defeated, 8th Essex District Representative Bruce McLaughlin in the Democratic primary. After defeating Salem City Councilman Steve Lovely in the 1980 Democratic Primary, Ruane would not face another challenger for 22 years.

From 1996 until his retirement in 2005, he was the vice chairman House Ways and Means Committee.

Death
Ruane died on June 25, 2006, at the Kaplan Family Hospice House in Danvers, Massachusetts. He was survived by his wife Helena and two of their children. A daughter, Christine, and a son, Patrick, predeceased him.

References

1927 births
2006 deaths
20th-century American politicians
Democratic Party members of the Massachusetts House of Representatives
Politicians from Salem, Massachusetts
Danny Joe is a former Canadian politician. He represented the electoral district of Tatchun from 1987 to 1992, and Mayo-Tatchun from 1992 to 1996, in the Yukon Legislative Assembly.

A member of the Yukon New Democratic Party, Joe was formerly a Chief of the Selkirk First Nation. He first won the riding in a by-election in 1987, following the resignation of Roger Coles, and was reelected in the 1989 election. He was subsequently re-elected in the redistricted Mayo-Tatchun in the 1992 election. He did not run again in 1996 and was replaced by Eric Fairclough who also won the riding for the NDP.

References

1929 births
20th-century Canadian politicians
20th-century First Nations people
First Nations politicians
Indigenous leaders in Yukon
Living people
Tutchone people
Yukon New Democratic Party MLAs
Glutathione peroxidase 2 is an enzyme that in humans is encoded by the GPX2 gene.

This gene is a member of the glutathione peroxidase family encoding a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract.

The antioxidant enzyme glutathione peroxidase 2 (Gpx2) is one out of eight known glutathione peroxidases (Gpx1-8) in humans. Mammalian Gpx1, GPx2 (this protein), Gpx3, and Gpx4 have been shown to be selenium-containing enzymes, whereas Gpx6 is a selenoprotein in humans with cysteine-containing homologues in rodents. In selenoproteins, the 21st amino acid selenocysteine is inserted in the nascent polypeptide chain during the process of translational recoding of the UGA stop codon.

References

Further reading

EC 1.11.1
Selenoproteins
Gisela Cerezo (born 5 April 1956) is a Venezuelan former swimmer. She competed in two events at the 1972 Summer Olympics.

References

1956 births
Living people
Venezuelan female swimmers
Olympic swimmers for Venezuela
Swimmers at the 1972 Summer Olympics
Place of birth missing (living people)
Central American and Caribbean Games gold medalists for Venezuela
Central American and Caribbean Games medalists in swimming
Competitors at the 1974 Central American and Caribbean Games
20th-century Venezuelan women
Lorena Corona Valdés (born 16 December 1972) is a Mexican politician from the Ecologist Green Party of Mexico. She serves as a federal deputy to the LXIII Legislature of the Mexican Congress representing Durango and the first electoral region.

Life
Corona received her law degree from the Instituto Tecnológico Autónomo de México (ITAM) in 1997 and worked primarily as a communications lawyer. Between 2001 and 2006, she was the legal director of Televisa Radio (Sistema Radiópolis, S.A. de C.V.); during this time, she obtained graduate degrees in intellectual property law and in operating broadcasting companies, and she was also named by Vicente Fox to serve on the Federal Telecommunications Commission. After she left Televisa Radio, she worked at Ecija Abogados from 2006 to 2007 and at Legal Media Advisers from 2007 to 2008.

From 2009 to 2012, Corona spent her first term in the Chamber of Deputies for the LXI Legislature, where she sat on the Public Education and Educational Services Commission as well as those dealing with Government and National Defense. She returned to the chamber in 2015, again as a proportional representation deputy; she sits on the Economy, Constitutional Points, and Culture and Film Commissions.

References

1972 births
Living people
Politicians from Durango
Women members of the Chamber of Deputies (Mexico)
Members of the Chamber of Deputies (Mexico) for Durango
Ecologist Green Party of Mexico politicians
21st-century Mexican politicians
21st-century Mexican women politicians
Instituto Tecnológico Autónomo de México alumni
Mexican women lawyers
Deputies of the LXIII Legislature of Mexico
Gérard Watkins (born 4 July 1965) is an English-French actor, playwright, director, and songwriter.

He graduated from Lycée de St Germain en Laye in 1983.

As a stage actor, he has performed in over forty productions in Paris with such directors as Véronique Bellegarde, Julie Beres, Jean-Claude Buchard, Elizabeth Chailloux, Michel Didym, André Engel, Frederic Fisbach, Marc François, Daniel Jeanneteau, Philipe Lanton, Jean-Louis Martinelli, Lars Noren, Claude Régy, Yann Ritsema, Bernard Sobel,  Viviane Theophilides, and Jean-Pierre Vincent.

Among his critically acclaimed performances are Ian in Sarah Kane's Blasted, Edmond in King Lear, and Rosalind in As You Like It. In the cinema, he is perhaps best known for his role in the 2008 film Taken as Patrice Saint Clair, the sex trafficking kingpin who runs the operation that kidnapped the protagonist's 17-year-old daughter, but he has also performed with directors such as Julie Lopes-Curval, Jérome Salle, Yann Samuel, Julian Schnabel, Hugo Santiago, and Peter Watkins. Since 1994, he has directed his own theatre company, the Perdita Ensemble, where he has staged all of his plays, The Secret Capital, Follow Me, The Tower, In the Faraway Forest, Icone, Identity, Lost (Replay), and I Don't Remember Very Well.

He is fluent in both English and French.

He was awarded the Grand Prix de littérature dramatique in 2010 for his play Identité.

Filmography

References

External links

English male film actors
1965 births
Living people
Male actors from London
20th-century English male actors
21st-century English male actors
H.N. Jacobsens Bókahandil is the oldest bookshop in the Faroe Islands. It is also one of the oldest shops still in business in the Faroes today.

The bookshop was established on St. Olafs day on 29 July 1865 by bookbinder Hans Nicolai Jacobsen. He was the father of Jakob Jakobsen (1864-1918), who is one of the most important Faroese philologists.

H. N. Jacobsen was one of the initiators of a public meeting in Tórshavn in 1888, aiming at public support for “the protection and preservation of the Faroese language and traditions”, as the notice announcing the meeting said. This is considered as the official start of the Faroese National Movement.

The original book shop was in the old main street "Gongin", but 1918 it was moved to the Market Square "Vaglið", at the start of Niels Finsens gøta, where it still stands today.

With its characteristic Faroese grass roof and big maple trees in the foreground, it is a landmark in Tórshavn.  
In addition, a section of H.N. Jacobsens Bókahandil operates an antiquarian bookshop.

External links
 H. N. Jacobsens Bókahandil

Bookstores of the Faroe Islands
Buildings and structures in the Faroe Islands
Organizations established in 1865
Élie Fallu (born March 2, 1932) is a politician in the Canadian province of Quebec, who was a two-term member of the National Assembly of Quebec, representing the district of Terrebonne in 1976-1981 and the district of Groulx in 1981–1985. He is a member of the Parti Québécois.

He was born in 1932 in the Gaspésie area to a farming household, attended University of Ottawa, Université de Montréal, Université Laval, University of Sorbonne and holds a PhD in History.

He was a card-carrying member of the Progressive Conservative Party of Canada in 1957 and 1958.

He ran for a seat in the Parliament of Quebec in 1976, against Liberal incumbent Denis Hardy and won with 51% of the vote.  He was re-elected in a two-way race in 1981 with 57% of the vote, but was narrowly defeated in 1985, with 47% of the vote, against Liberal candidate Madeleine Bleau.

Fallu served as a cabinet member in the administrations of Premiers René Lévesque and Pierre-Marc Johnson.

He also was mayor of Sainte-Thérèse, Quebec from 1987 until 2005.

References

External links 
 

Living people
1932 births
Parti Québécois MNAs
University of Paris alumni
Université de Montréal alumni
People from Gaspésie–Îles-de-la-Madeleine
Canadian expatriates in France
João Miguel Afonso Fernandes (born 2 July 1983) is a Portuguese football player who plays for Montalegre.

Club career
He made his professional debut in the Segunda Liga for Chaves on 26 September 2004 in a game against Leixões.

References

1983 births
People from Chaves, Portugal
Living people
Portuguese men's footballers
G.D. Chaves players
Liga Portugal 2 players
C.D. Feirense players
Gondomar S.C. players
Juventude de Pedras Salgadas players
SC Mirandela players
C.D.C. Montalegre players
Men's association football midfielders
Footballers from Vila Real District
The Jefferson County Library Cooperative (JCLC) is a 501(c)(3) tax-exempt educational consortium of public libraries in Jefferson County, Alabama. The JCLC administrative office is located at the Birmingham Public Central Library. The member libraries within the cooperative are autonomous, with each one maintaining its own board, director and budget.

History
Jefferson County has had a countywide public library service since 1924, however, no-fee service for Jefferson County citizens began in 1978. In 1985, it was reorganized as Birmingham Area Library Services under the framework issued by the Alabama Public Library Service. In 1997, it was renamed the Jefferson County Library Cooperative and continues to operate as a not-for-profit educational organization.

Member libraries
 Adamsville Library
 Avondale Regional Branch Library
 Bessemer Library
 Birmingham Botanical Gardens Library
 Central Library
 East Ensley Branch Library
 East Lake Branch Library
 Eastwood Branch Library
 Emmet O'Neal Library
 Ensley Branch Library
 Five Points West Regional Library
 Fultondale Library
 Gardendale-Martha Moore Library
 Graysville Public Library
 Homewood Library
 Hoover Public Library
 Hueytown Public Library
 Inglenook Branch Library
 Irondale Public Library
 Leeds-Jane Culbreth Public Library
 Midfield Public Library
 North Avondale Branch Library
 North Birmingham Regional Branch Library
 Pleasant Grove Public Library
 Powderly Branch Library
 Pratt City Branch Library
 Slossfield Branch Library
 Smithfield Branch Library
 Southside Branch Library
 Springville Road Regional Branch Library
 Tarrant Public Library
 Titusville Branch Library
 Trussville Public Library
 Vestavia Hills Public Library
 Walter J. Hanna Library
 Warrior-Evelyn Thornton Public Library
 West End Branch Library
 Woodlawn Branch Library
 Wylam Branch Library

References

External links
Jefferson County Library Cooperative
Jefferson County Library Cooperative Catalog
Map of the Jefferson County Library Cooperative's Libraries

Education in Jefferson County, Alabama
Library consortia in Alabama
Neurotensin receptors are transmembrane receptors that bind the  neurotransmitter neurotensin. Two of the receptors encoded by the  and  genes contain seven transmembrane helices and are G protein coupled. Numerous crystal structures have been reported for the neurotensin receptor 1 (NTS1). The third receptor has a single transmembrane domain and is encoded by the  gene.

Ligands

Agonists 

Peptide
 Beta-lactotensin (NTS2)
 JMV-449
 Neurotensin
 Neuromedin N (NTS1 selective)
 PD-149,163 (NTS1 selective, reduced amide bond 8-13 fragment of neurotensin)

Non-peptide
 NTS1 full agonist SRI-9829 
 Partial agonists derived from SR-48692

Antagonists 

 Levocabastine (NTS2 selective, also H1 histamine antagonist)
 SR-48692 (NTS1 selective)
 SR-142948 (unselective, CAS# 184162-64-9)

Biophysical Investigation 
Unusually for GPCRs, NTS1 can be expressed in an active form in the bacteria E. coli.  It can be purified and analysed in vitro and has been analysed by a number of biophysical techniques such as surface plasmon resonance, FRET and cryo-electron microscopy.
Furthermore, high-resolution crystal structures of NTS1 have been determined in complex with the peptide full agonist NT8-13, the non-peptide full agonist SRI-9829, the partial agonist RTI-3a, and the antagonists / inverse agonists SR-48692 and SR-142948, as well as in the ligand-free apo state

References

External links 

 

G protein-coupled receptors
Keralotsavam is the national Youth Festival of Kerala. It is coordinated by Kerala State Youth Welfare Board. The event Organised by Government of Kerala mostly starts by November and ends generally around December. The last Keralotsavam was Keralotsavam 2021 started on November 25, 2021 and Ended on January 1, 2022. Due to Covid 19, Board decided to conduct only Arts Competition for 2021 and that too online. The Online system for conducting by uploading videos and evaluating them online, First time in India for such an event, was developed by Klivolks Private Limited in a limited period of time with utmost precision.

Nature of Event 
Keralotsavam consist of two main categories of competitions which are basically arts and sports. It includes performing arts, creative arts and Sports competitions including cricket and football. The event starts with LSGD level and occurs till National level as part of National youth festival.

References

Festivals in Kollam district
Sir James Harwood Harrison, 1st Baronet (6 June 1907 – 11 September 1980) was a British Conservative Party politician. He was the Member of Parliament (MP) for the constituency of Eye in Suffolk from 1951 to 1979, having first contested it in 1950.

Harrison was the eldest son of the Rev'd E W Harrison and E E Tribe of Bugbrooke, Northamptonshire where his family had owned land since the eighteenth century. The family home, Bugbrooke Hall, is now owned by the Jesus Army. He was educated at Northampton Grammar School and Trinity College, Oxford and worked as a company director for a feeding-stuffs manufacturer. He served as an Ipswich Borough Councillor from 1935 to 1946 and served during World War II with The Suffolk Regiment, commanding the 4th Battalion. He was taken prisoner in Singapore and spent time on the Burma Railway.

Harrison won Eye at the 1951 general election, defeating Edgar Granville. He was Harold Macmillan's Parliamentary Private Secretary when Macmillan was Housing Secretary. He served as a Government Whip as a Lord of the Treasury from 8 April 1956 to 16 January 1959, and Comptroller of the Household between 1959 and 1961. He subsequently chaired backbench Conservative committees. He was created a Baronet on 6 July 1961.

On his retirement as MP for Eye at the 1979 general election, the seat was contested by another Conservative, John Gummer, elected with a majority of 27%. The seat was abolished at 1983 general election and was divided up into the three new seats: Suffolk Coastal, Central Suffolk and Waveney, all of which returned Conservative candidates. Gummer was elected Member of Parliament for Suffolk Coastal, Michael Lord for Central Suffolk and James Prior for Waveney.

He married Peggy Stenhouse, daughter of Lt Col V D Stenhouse in 1932 and had two children, Sir Michael James Harwood Harrison, 2nd Baronet, and Joanna Kathleen Sanders.

He is buried in the churchyard of St Michael and All Angels', Bugbrooke, Northamptonshire.

References

External links 
 

Conservative Party (UK) MPs for English constituencies
1907 births
1980 deaths
Alumni of Trinity College, Oxford
Baronets in the Baronetage of the United Kingdom
British Army personnel of World War II
Burma Railway prisoners
Councillors in Suffolk
Ministers in the Eden government, 1955–1957
Ministers in the Macmillan and Douglas-Home governments, 1957–1964
People from Bugbrooke
Suffolk Regiment officers
UK MPs 1951–1955
UK MPs 1955–1959
UK MPs 1959–1964
UK MPs 1964–1966
UK MPs 1966–1970
UK MPs 1970–1974
UK MPs 1974
UK MPs 1974–1979
World War II prisoners of war held by Japan
Military personnel from Northamptonshire
[[Category:British World War II prisoners of war][