Samantha912/NLP_A2_WTH huggingface dataset:
Jerini AG was a pharmaceutical company based in Berlin, Germany, which focused on the discovery and development of novel peptide-based drugs. Using a proprietary technology platform, Peptides-to-Drugs (P2D), Jerini pursued disease indications for which limited, inadequate, or no treatment options exist. As a result, Jerini established a drug pipeline composed of its own programs as well as others in collaboration with partners. Jerini's commercialization strategy was to market new drugs in niche indications independently and in larger indications with partners. Jerini was acquired by Shire plc in 2008.

Jerini started operations in 1994. Jerini's subsidiaries Jerini US Inc. and JPT Peptide Technologies GmbH, provider of peptides and peptide microarrays, were acquired by Theracode GmbH, Mainz in 2009. Jerini was financed with venture capital provided by TVM and HealthCap. It went public on the Prime Standard of the Frankfurt Stock Exchange (JI4), and had raised a total of over 130 million Euro in public and private financing to date.

Firazyr (icatibant)
Jerini's lead compound Firazyr (icatibant), is an inhibitor of the action of the hormone bradykinin on its B2 receptor. This compound was in-licensed from Aventis in 2001. It has been approved for hereditary angioedema in all member states of the European Union in July 2008. The drug was granted FDA approval on August 25, 2011.

Peptides-to-Drugs (P2D) platform 
Based on its P2D platform, Jerini established several in-house development programs, to address indications within the ophthalmology, oncology, and inflammatory therapeutic areas. The most advanced of these programs targeted age-related macular degeneration (AMD), the leading cause of vision loss and blindness in people over the age of 55 in developed countries. Jerini's compound (JSM 6427) has shown significant efficacy in combating disease progression in preclinical models.

Jerini's proprietary Peptides-to-Drugs (P2D) technology was used to identify peptide drug lead structures and systematically transform them into peptidomimetic (injectable) and small-molecule (oral) drugs, depending on the indication. This enabled Jerini to develop novel drug candidates for diseases that were difficult to access using traditional drug discovery methods. The ability to produce both peptidomimetics and small molecule drugs as drug candidates has enabled the simultaneous development of drugs for acute and chronic treatments against the same target molecule (target).

References

External links
 Official website
 JPT Peptide Technologies
 European HAE information portal

Pharmaceutical companies disestablished in 2008
Manufacturing companies based in Berlin
Pharmaceutical companies of Germany
Pharmaceutical companies established in 1994
Medical and health organisations based in Berlin
2008 mergers and acquisitions
The rufous-backed antvireo (Dysithamnus xanthopterus) is a species of bird in the family Thamnophilidae. It is endemic to Brazil.

Its natural habitat is subtropical or tropical moist montane forests.

References

External links
Xeno-canto: audio recordings of the rufous-backed antvireo

Dysithamnus
Birds of the Atlantic Forest
Endemic birds of Brazil
Birds described in 1856
Taxonomy articles created by Polbot
Stojkovačka planina (Serbian Cyrillic: Стојковачка планина) is a mountain in southwestern Serbia, above the town of Ivanjica. Its highest peak has an elevation of 1,360 meters above sea level.

References

Mountains of Serbia
The 2019 Portland State Vikings football team represented Portland State University during the 2019 NCAA Division I FCS football season. They were led by fifth-year head coach Bruce Barnum and played their home games at Hillsboro Stadium. They were a member of the Big Sky Conference. They finished the season 5–7, 3–5 in Big Sky play to finish in a three-way tie for sixth place.

Previous season
The Vikings finished the 2018 season 4–7, 3–5 in Big Sky play to finish in a tie for ninth place.

Preseason

Big Sky preseason poll
The Big Sky released their preseason media and coaches' polls on July 15, 2019. The Vikings were picked to finish in tenth place in both polls.

Preseason All–Big Sky team
The Vikings had two players selected to the preseason all-Big Sky team.

Offense

Charlie Taumopeau – TE

Defense

Kenton Bartlett – DT

Schedule

Source:

Game summaries

At Arkansas

Simon Fraser

At Boise State

Eastern Oregon

At Idaho State

Southern Utah

Idaho

At Northern Colorado

At Northern Arizona

Montana

UC Davis

At Eastern Washington–The Dam Cup

References

Portland State
Portland State Vikings football seasons
Portland State Vikings football
Portland State Vikings football
Sports in Hillsboro, Oregon
Chevez Ezaneh (born August 12, 1992) is a young Dene actor who has played characters who are Native Americans, including the young Charles Eastman in the HBO TV film Bury My Heart at Wounded Knee. Ezaneh won a Young Artist Award in 2008 for the "Best Performance in a TV Movie.

Appearances

External links

Living people
1992 births
21st-century First Nations people
Canadian male film actors
Canadian male television actors
Dene people
First Nations male actors
Dyschirius aida is a species of ground beetle in the subfamily Scaritinae. It was described by Schatzmayr in 1936.

References

aida
Beetles described in 1936
Jonathan Wright (born 1969) is a British historian and author.

His books include The Jesuits: Missions, Myths and Histories (HarperCollins, 2004), published in the United States as God's Soldiers (Doubleday, 2004), and The Ambassadors: From Ancient Greece to the Nation State (HarperCollins, 2006), and Heretics: The Creation of Christianity from the Gnostics to the Modern Church (Houghton Mifflin Harcourt, 2011) (on heresy).

Wright was educated at the Universities of St Andrews and Oxford where he was awarded a doctorate in 1999. Wright reviews for numerous British and American newspapers, magazines and academic journals.

References

1969 births
Living people
British historians
British writers
Semiahmoo Bay ( ) is the southeastern section of Boundary Bay on the Pacific coast of North America. The bay is named for the  Semiahmoo First Nation, who originally occupied the area. The Semiahmoo Peninsula borders the bay and was home to cannery operations. It is now home to the Semiahmoo Golf Resort.

From the north to south, the following communities and places are located on its shore:
 North of the  border, in British Columbia:
 the Crescent Beach and Ocean Park neighbourhoods of the city of Surrey
 the city of White Rock
 the Semiahmoo Indian Reserve of the Semiahmoo First Nation
 Peace Arch Provincial Park
 South of the border, in Washington State:
 Peace Arch State Park
 Blaine

Blaine's Drayton Harbor opens into Semiahmoo Bay; the harbor is separated from the main body of the bay by Semiahmoo Spit. The Semiahmoo Resort is located south of the spit.

The Washington State Department of Ecology classified the marine waters within Semiahmoo Bay, outside of Drayton Harbor, as extraordinary quality waters for (1) salmonid and other fish migration, rearing, and spawning; (2) clam, oyster, and mussel rearing and spawning; and (3) crustaceans and other shellfish (crabs, shrimp, crayfish, and scallops) rearing and spawning.

The Campbell River flows into Semiahmoo Bay on the Canadian side; California Creek and Dakota Creek flow into Drayton Harbor on the US side.

External links 

Birds on the Bay, by  Friends of Semiahmoo Bay Society

Bays of British Columbia
Bays of Washington (state)
Landforms of Lower Mainland
Surrey, British Columbia
Bodies of water of Whatcom County, Washington
White Rock, British Columbia
Washington placenames of Native American origin
Iain Baxter (4 December 1948 – 29 July 2015) was a Scottish curler.

He was a  and a two-time Scottish men's champion (1971, 1978).

He was also 1978 Scottish Mixed Curling champion and two-time Scottish senior men's champion (2002, 2003).

Teams

Men's

Mixed

Personal life
His brother Colin is also a curler and Iain's teammate. Their parents, father Bobby and mother Mabel, were curlers too.

References

External links
 

1948 births
2015 deaths
Scottish male curlers
Scottish curling champions
Curlers from Edinburgh
Terry Wey (born 15 September 1985) is a classical countertenor, specialising in historically informed performance. As a boy soprano, he was a soloist of the Wiener Sängerknaben.

Born in Bern in a Swiss-American family of musicians, Wey began his vocal training as a member of the Wiener Sängerknaben and also studied the piano. From 2003, he appeared internationally in concert- and opera. His love of Renaissance music made him join the vocal ensemble Cinquecento.

Selected recordings 

 Tommaso Albinoni: Il Nascimento dell’Aurora (2007)
 Stefano Landi: Il Sant’Alessio (2008)
 Johann Sebastian Bach: Mass in B minor (2008)
 George Frederic Handel: Israel in Egypt (2008)
 Claudio Monteverdi: Il Ritorno d'Ulisse in Patria (2010)
 Bach: Es ist ein trotzig und verzagt Ding, BWV 176 (2014)

References

External links 

 
 
 Terry Wey autobiography, boychoirs.org 2002

Countertenors
1985 births
Living people
American people of Swiss descent
Musicians from Bern
Audrey Young (October 30, 1922 – June 1, 2012) was an American film actress and a big-band singer who was most active in the 1940s. She was the wife of director Billy Wilder.

Early years 
Young was born in Los Angeles, California, Her father, Stratton Young, built sets for films.

Career 
Young was a contract actor with Paramount Pictures in the 1940s, appearing in approximately 20 films from 1944 to 1949. Her film debut came in Lady in the Dark (1944). She had sung with Tommy Dorsey's orchestra before becoming an actress, and she sang (either solo or as part of a group) in several films, including Blue Skies. Most of her roles were small and uncredited, with only a few exceptions like Danger Street and The Wistful Widow of Wagon Gap. Her final film appearance was in Love in the Afternoon (1957) in an uncredited role as the opera date of Gary Cooper's character.

On November 1, 1944, Young appeared on a Paramount Studios television variety program that was broadcast on station W6XYZ (later KTLA) in Los Angeles. She sang "What a Difference a Day Makes" and "Getting Sentimental Over You". In a review in the trade publication Billboard, Cy Wagner wrote that Young "had a nice voice and was very telegenic." She also sang in vaudeville.

Young worked as a costume consultant on two films, The Apartment and Some Like It Hot, both directed by her husband.

Personal life 
On June 30, 1949, Young married director Billy Wilder in Linden, Nevada. They first met when she appeared in a small role as a Cloak Room Attendant in The Lost Weekend and were married until his death in 2002. They had no children, but she was stepmother to Wilder's child from an earlier marriage. After Wilder's death, Young donated $5 million to the Hammer Museum at UCLA to create the Billy Wilder Theater.

References

External links 

 

1922 births
2012 deaths
20th-century American actresses
American film actresses
Actresses from Los Angeles
20th-century American women singers
20th-century American singers
21st-century American women
Sam Gallagher may refer to:
 Sam Gallagher (Australian rules footballer), Australian rules footballer.
 Sam Gallagher (footballer, born 1995), English footballer.
 Sam Gallagher (soccer, born 1991), Australian footballer.

See also
 Sam Gallacher (born 1904), Scottish footballer.
The 39th Los Angeles Film Critics Association Awards, given by the Los Angeles Film Critics Association (LAFCA), honored the best in film for 2013.

Winners

Best Picture (TIE):
Gravity
Her
Best Director:
Alfonso Cuarón – Gravity
Runner-up: Spike Jonze – Her
Best Actor:
Bruce Dern – Nebraska
Runner-up: Chiwetel Ejiofor – 12 Years a Slave
Best Actress (TIE):
Cate Blanchett – Blue Jasmine
Adèle Exarchopoulos – Blue Is the Warmest Colour
Best Supporting Actor (TIE):
James Franco – Spring Breakers
Jared Leto – Dallas Buyers Club
Best Supporting Actress:
Lupita Nyong'o – 12 Years a Slave
Runner-up: June Squibb – Nebraska
Best Screenplay:
Richard Linklater, Ethan Hawke, and Julie Delpy – Before Midnight
Runner-up: Spike Jonze – Her
Best Cinematography:
Emmanuel Lubezki – Gravity
Runner-up: Bruno Delbonnel – Inside Llewyn Davis
Best Editing:
Alfonso Cuarón and Mark Sanger – Gravity
Runner-up: Shane Carruth and David Lowery – Upstream Color
Best Production Design:
K. K. Barrett – Her
Runner-up: Jess Gonchor – Inside Llewyn Davis
Best Music Score:
T Bone Burnett – Inside Llewyn Davis
Runner-up: Arcade Fire and Owen Pallett – Her
Best Foreign Language Film:
Blue Is the Warmest Colour • France
Runner-up: The Great Beauty • Italy
Best Documentary/Non-Fiction Film:
Stories We Tell
Runner-up: The Act of Killing
Best Animation:
Ernest & Celestine
Runner-up: The Wind Rises
New Generation Award:
Megan Ellison
Career Achievement Award:
Richard Lester
The Douglas Edwards Experimental/Independent Film/Video Award:
Charlotte Pryce – Cabinets of Wonder: Films and a Performance by Charlotte Pryce

References

External links
 39th Annual Los Angeles Film Critics Association Awards

2013
2013 film awards
2013 in American cinema
2013 in Los Angeles
December 2013 events in the United States
Vytautas Kernagis (born 20 August 1976 in Vilnius) is a Lithuanian politician, a Member of the Seimas for Pašilaičiai constituency. Also he is a former organizer of Lithuanian public initiatives, Member of the Council of the Association of Related Rights AGATA, Head of the Vytautas Kernagis Foundation.

Biography
Vytautas Kernagis father is musician and performer Vytautas Kernagis, and his mother is costume designer Dalia Kernagienė.
Since 1996 until 2000 studied at Vilnius Higher School of Electronics. In 2005, he defended his bachelor's thesis at the Faculty of Electronics and Informatics of Vilnius College.
Between 2008 and 2016 Kernagisfounded and managed the Vytautas Kernagis Charity and Support Foundation, the main goals of which are to preserve the memory of Vytautas Kernagis, carry out the dissemination of new creative ideas and organize help for patients with oncological diseases. Over the past 8 years, he has created over 70 educational and cultural projects, including performances, festivals, concert programs, children's stage mastery camps, non-formal education workshops, publishing, and more.
In November 2016 he became Member of the Seimas of the Republic of Lithuania for Fabijoniškės constituency.

References

1976 births
Living people
Members of the Seimas
Homeland Union politicians
21st-century Lithuanian politicians
Mount Turner, also known as Boundary Peak 162, is an 8,661+ foot (2,640+ meter) glaciated mountain summit located in the Fairweather Range of the Saint Elias Mountains, on the Canada–United States border between southeast Alaska and British Columbia. The peak is situated on the shared boundary of Glacier Bay National Park with Tatshenshini-Alsek Provincial Park,  west of Tarr Inlet, and  southwest of Mount Forde, which is the nearest peak. Turner is the highest point on the divide which separates Ferris Glacier from Margerie Glacier. The mountain's name was officially adopted by the Geographical Names Board of Canada on March 31, 1924. The mountain was named for George Turner (1850–1932), one of the US members of the 1903 Alaska Boundary Tribunal.

Climate

Based on the Köppen climate classification, Mount Turner has a subarctic climate with cold, snowy winters, and mild summers. Temperatures can drop below −20 °C with wind chill factors below −30 °C. This climate supports small hanging glaciers on its slopes as well as the larger Margerie Glacier to the south and Ferris Glacier to the north. Precipitation runoff and meltwater from its glaciers drains into Glacier Bay Basin.

See also

List of Boundary Peaks of the Alaska–British Columbia/Yukon border
Geography of Alaska
Geography of British Columbia

References

Mountains of Glacier Bay National Park and Preserve
Saint Elias Mountains
Landforms of Hoonah–Angoon Census Area, Alaska
Two-thousanders of British Columbia
Mountains of Alaska
North American 2000 m summits
Heylaertsia quadripuncta is a moth of the family Psychidae first described by George Hampson in 1897. It is found in Sri Lanka.

References

Moths of Asia
Moths described in 1892
Psychidae
Acta Oeconomica is a quarterly peer-reviewed academic journal published by Akadémiai Kiadó. It covers theoretical and general issues related to the East European and Hungarian transition processes, economic policy, econometric methods, and economic modelling.

The journal was established in 1966 by the Hungarian Academy of Sciences and is a hybrid open-access journal. The editor-in-chief is Péter Mihályi (Corvinus University of Budapest).

Abstracting and indexing
The journal is abstracted and indexed in:

According to the Journal Citation Reports, the journal has a 2021 impact factor of 0.939, ranking it 326 out of 379 journals in the category "Economics".

References

External links

Economics journals
English-language journals
Quarterly journals
Academic journals established in 1966
Akadémiai Kiadó academic journals
The Echo Protocol is a service in the Internet Protocol Suite defined in RFC 862. It was originally proposed for testing and measurement of round-trip times in IP networks.

A host may connect to a server that supports the Echo Protocol using the Transmission Control Protocol (TCP) or the User Datagram Protocol (UDP) on the well-known port number 7. The server sends back an identical copy of the data it received.

Inetd implementation
On UNIX-like operating systems an echo server is built into the inetd family of daemons. The echo service is usually not enabled by default. It may be enabled by adding the following lines to the file  and telling inetd to reload its configuration:
 echo   stream  tcp     nowait  root    internal
 echo   dgram   udp     wait    root    internal

On various routers, this TCP or UDP port 7 for the Echo Protocol for relaying ICMP datagrams (or port 9 for the Discard Protocol) is also configured by default as a proxy to relay Wake-on-LAN (WOL) magic packets from the Internet to hosts on the local network in order to wake them up remotely (these hosts must also have their network adapter configured to accept WOL datagrams and the router must have this proxy setting enabled, and possibly also a configuration of forwarding rules in its embedded firewall to open these ports on the Internet side).

See also
 Discard Protocol
 Daytime Protocol
 QOTD
 Character Generator Protocol
 Time Protocol
 ICMP Echo Request

References

External links
RFC 347 Echo Process
RFC 862 Echo Protocol

Application layer protocols
Robin Briggs,  (born 26 May 1942) is an English historian who has spent his entire academic career at All Souls College, Oxford.

Early life and education
Born in Braintree to Donald Frederick and Kathleen Ann Briggs, he went up to Balliol College, Oxford, in 1961 and graduated with a first-class modern history Bachelor of Arts degree in 1964.

Academic career
He was appointed a fellow of All Souls College, Oxford, that year, after passing its examination; he was then appointed a junior research fellow there in 1971 and then senior research fellow seven years later. Briggs remained in that post until retiring and being appointed an emeritus fellow at All Souls in 2009. From 1976 to 2009, he also lectured for the University of Oxford, and was junior proctor in the 1972–73 year.

His research interests include the history of witchcraft in Europe and other aspects of early modern European history (especially politics, society and religion, and the history of early modern France and the French Catholic Church).

Honours 
Briggs was elected a Fellow of the Royal Historical Society in 1969, a Fellow of the Royal Society of Literature in 2002 and a Fellow of the British Academy in 2009 (the latter being the United Kingdom's national academy for the humanities and social sciences).

Selected publications 
 The Witches of Lorraine (Oxford University Press, 2007).
 Witches and Neighbours: The Social and Cultural Context of European Witchcraft (Harper Collins, 1996).
 "The Académie Royale des Sciences and the pursuit of utility", Past and Present, vol. 131 (1991), pp. 38–88.
 Communities of Belief: Social and Cultural Tensions in Early Modern France (Oxford University Press, 1989).
 Early Modern France, 1560–1715 (Oxford University Press, 1977).

References 

Living people
1942 births
People from Braintree, Essex
English historians
Alumni of Balliol College, Oxford
Fellows of All Souls College, Oxford
Fellows of the Royal Historical Society
Fellows of the Royal Society of Literature
Fellows of the British Academy
In mathematics, a compact semigroup is a semigroup in which the sets of solutions to equations can be described by finite sets of equations.  The term "compact" here does not refer to any topology on the semigroup.

Let S be a semigroup and X a finite set of letters.  A system of equations is a subset E of the Cartesian product X∗ × X∗ of the free monoid (finite strings) over X with itself.  The system E is satisfiable in S if there is a map f from X to S, which extends to a semigroup morphism f from X+ to S, such that for all (u,v) in E we have f(u) = f(v) in S.  Such an f is a solution, or satisfying assignment, for the system E.

Two systems of equations are equivalent if they have the same set of satisfying assignments.  A system of equations if independent if it is not equivalent to a proper subset of itself.  A semigroup is compact if every independent system of equations is finite.

Examples
 A free monoid on a finite alphabet is compact.
 A free monoid on a countable alphabet is compact.
 A finitely generated free group is compact.
 A trace monoid on a finite set of generators is compact.
 The bicyclic monoid is not compact.

Properties
 The class of compact semigroups is closed under taking subsemigroups and finite direct products.
 The class of compact semigroups is not closed under taking morphic images or infinite direct products.

Varieties
The class of compact semigroups does not form an equational variety.  However, a variety of monoids has the property that all its members are compact if and only if all finitely generated members satisfy the maximal condition on congruences (any family of congruences, ordered by inclusion, has a maximal element).

References

 

Semigroup theory
Formal languages
Combinatorics on words