Samantha912/NLP_A2_WTH huggingface dataset:
Lipase inhibitors are substances used to reduce the activity of lipases found in the intestine. Lipases are secreted by the pancreas when fat is present. The primary role of lipase inhibitors is to decrease the gastrointestinal absorption of fats. Fats then tend to be excreted in feces rather than being absorbed to be used as a source of caloric energy, and this can result in weight loss in individuals. These inhibitors could be used for the treatment of obesity, which can subsequently lead to Type 2 diabetes and cardiovascular diseases if not managed. An example of a lipase inhibitor is orlistat.

Mechanism

Lipase inhibitors may affect the amount of fat absorbed, yet they do not block the absorption of a particular type of fat. Likewise, lipase inhibitors are not absorbed into the bloodstream. Lipase inhibitors bind to lipase enzymes in the intestine, thus preventing the hydrolysis of dietary triglycerides into monoglycerides and fatty acids. This then reduces the absorption of dietary fat. Lipase inhibitors covalently bond to the active serine site on lipases. This covalent bond is strong, meaning the lipase inhibitor tends to remain attached to the lipase.  Studies have shown that lipase inhibitors work optimally when 40% of an individual's daily caloric intake is obtained from fat. Orlistat tends to block absorption of 30% of total fat intake from a meal, as orlistat passes out of the digestive tract more rapidly than fat does.

Sources

Lipase inhibitors can be found naturally in plants and can also be produced as pharmaceutical drugs.  Some lipase inhibitors have been identified in Panax ginseng. Some active compounds with chalcone scaffold found in Glycyrrhiza glabra, Cassia mimosoides, Glycyrrhiza uralensis, Boesenbergia rotunda, apples and Morus alba also had strong effect against lipase. Caffeine, theobromine and theophylline were also supposed as lipase inhibitors although they are still controversial.

Side effects

Lipase inhibitors can cause side effects, including oily spotting, fecal incontinence, flatus with discharge  and abdominal cramping. Additionally, a raise in blood pressure, dry mouth, constipation, headache, and insomnia have been reported.  Malabsorption of fat soluble vitamins may develop as a result of the impaired absorption of fat, which is required for the transportation of these vitamins across the intestine to reach the blood. Since lipase inhibitors are not absorbed in the intestine, and consequently not circulating in the blood, information about alternative side effects such as the modulation of the gastrointestinal tract is unobtainable. Generally, side effects can be controlled by reducing the consumption of dietary fats. Overall, orlistat has been considered to be safer than other anti-obesity drugs.

Cautions and Considerations 
Because Lipase inhibitors interferes with the absorption of fat, it can also prevent the absorption of fat-soluble vitamins. It is recommended that multi-vitamins are taken along with Lipase inhibitors, so vitamin-deficiency doesn't occur.

See also
 Discovery and development of gastrointestinal lipase inhibitors

References

 
Obesity
The Lost Childhood is the title of several books.  It may refer to -

 The Lost Childhood and Other Essays, a collection by Graham Greene, published 1951
 The Lost Childhood (Nir book), by Yehuda Nir, published 2002
Samuel (L) Bruce Richards was the first Dean of Trinidad.
He worked at Saint Philip, Barbados before coming to Trinidad where he set up a school for the children of church goers.

References

1955 births
Deans of Trinidad
Living people
Frihedsfonden was founded on May 31, 1945. It was a charity for the families of fallen members of the Danish resistance movement until its dissolution in 1996.

References

External links

World War II non-governmental organizations
Non-profit organizations based in Denmark
Sarothroceras is a monotypic moth genus of the family Erebidae erected by Paul Mabille in 1889. Its only species, Sarothroceras banaka, was first described by Carl Plötz in 1880. It is found in Benin, Cameroon, the Democratic Republic of the Congo, Ivory Coast, Equatorial Guinea, Gabon, Ghana, Nigeria, Nigeria, Tanzania and Uganda.

References

Calpinae
Monotypic moth genera
Josip Bonacin (born 10 February 1984) is a Croatian former footballer who played in the Croatian Second Football League, Croatian First Football League, Liga I, Kazakhstan Premier League, Canadian Soccer League, Premier League of Bosnia and Herzegovina, and First County Football League.

Club career
Josip began his career playing for his home town, NK Solin in the Croatian Second Football League appearing 41 time and scored once for the team. Bonacin has previously played in the Croatian Prva HNL for NK Međimurje and HNK Šibenik. In 2009, he went abroad to Romania to play with FC Unirea Alba Iulia in the Liga I. After one season in Romania he went to Asia to play with FC Zhetysu in the Kazakhstan Premier League.

After being released by FC Zhetysu he left Kazakhstan to attend a trial with the Malaysian Super League champions, Kelantan FA. Josip appeared with Kelantan FA in a friendly match against Indonesian outfit, Pelita Jaya which ended in a 1–1 draw. In 2011, he returned home to play with NK Dugopolje in the 2.HNL. In 2012, he went overseas to Canada to sign with Toronto Croatia in the Canadian Soccer League. He made his debut on 30 September 2012 against Windsor Stars. During his short tenure with Toronto he won the regular season title, and the CSL Championship against Montreal Impact Academy.

He returned to the Balkans in 2013 to play with NK GOŠK Gabela in the Premier League of Bosnia and Herzegovina. In 2015, he returned to Croatia to play with NK Zagora Unešić, and Kastel Gomlica.

References

External links

1984 births
Living people
Men's association football defenders
Croatian men's footballers
NK Solin players
NK Međimurje players
HNK Šibenik players
CSM Unirea Alba Iulia players
FC Zhetysu players
NK Dugopolje players
Toronto Croatia players
NK GOŠK Gabela players
NK Zagora Unešić players
Liga I players
Expatriate men's footballers in Romania
First Football League (Croatia) players
Croatian Football League players
Kazakhstan Premier League players
Canadian Soccer League (1998–present) players
Premier League of Bosnia and Herzegovina players
Croatian expatriate men's footballers
Croatian expatriate sportspeople in Romania
Expatriate men's footballers in Kazakhstan
Croatian expatriate sportspeople in Kazakhstan
Expatriate men's soccer players in Canada
Croatian expatriate sportspeople in Canada
Expatriate men's footballers in Bosnia and Herzegovina
Croatian expatriate sportspeople in Bosnia and Herzegovina
KCVH-LD, virtual and VHF digital channel 6, is a low-power religious television station licensed to Houston, Texas, United States. The station is owned by Daij Media. KCVH-LD's transmitter is located near Missouri City, Texas, in unincorporated northeastern Fort Bend County.

History

It was formerly the flagship station for LAT TV, a Spanish-language network owned by Latin America Broadcasting. KCVH-LP was a charter station for the network, which launched in May 2006. In May 2008, LAT TV ceased broadcasting, and KCVH suspended operations on June 23, 2008.

In July 2009, the station was sold to Daij Media LLC. The station briefly returned to the air in February 2010 in analog as "Aleluya TV". An application to switch to digital broadcasting was granted by the FCC on February 25, 2010, the digital signal went on the air December 15, 2010, and religious programming began airing January 31, 2011.

References 

CVH-LD
Television channels and stations established in 1988
1988 establishments in Texas
CVH
Pacing and Clinical Electrophysiology  (PACE) is a peer-reviewed medical journal that publishes papers in cardiac pacing, clinical and basic cardiac electrophysiology, cardioversion-defibrillation, the electrical stimulation of other organs, cardiac assist, and, in general, the management of cardiac arrhythmias.

Abstracting and indexing 
The journal is abstracted and indexed in Current Contents, EMBASE, MEDLINE, Science Citation Index, and Scopus.

External links 
 

Cardiology journals
Monthly journals
English-language journals
Academic journals established in 1978
Wiley-Blackwell academic journals
Hele is a village in Devon, England, lying about  SSW of Bradninch and  NNE of Exeter, on the River Culm.

The village is home to a paper mill once belonging to the company Wiggins Teape, now part of the multinational company Purico Group. The Devon Valley Mill produces sausage casing paper and teabag paper under the "Crompton Paper" brand name.

The mill site was originally that of a grist mill which was converted to a paper mill in 1762. It was here that John Dewdney produced the first glazed writing paper in England in the 1840s. He was also famously called upon to supply the paper for the catalogues of the Great Exhibition in 1851.

The nearby railway station, now closed, used to serve Hele and Bradninch.

References

External links

Description in GENUKI - UK and Ireland genealogy 
Devon Valley Mill website

Villages in Devon
Bradninch
"Ready Teddy" is a song written by John Marascalco and Robert Blackwell, and first made popular by Little Richard in 1956. Little Richard sang and played piano on the recording, backed by a band consisting of Lee Allen (tenor saxophone), Alvin "Red" Tyler (baritone sax), Edgar Blanchard (guitar), Frank Fields (bass), and Earl Palmer (drums).

It has since been covered by Buddy Holly, The Tornados, Elvis Presley, Tony Sheridan and others, making it something of a rock and roll standard. The composition, an uptempo rock and roll song, received its largest ever recognition on the evening of September 9, 1956, as Presley sang it in front of some 60 million television viewers during his first appearance on The Ed Sullivan Show on CBS, a broadcast which received a Trendex percentage share of 82.6, the largest ever obtained in the history of U.S. television. It was later used in Federico Fellini's La Dolce Vita (1960) as a version by Italian rocker Adriano Celentano.

References

1956 songs
1956 singles
Little Richard songs
Buddy Holly songs
Elvis Presley songs
Songs written by Robert Blackwell
Songs written by John Marascalco
Song recordings produced by Robert Blackwell
Specialty Records singles
Sharon Hordes was ordained as Reconstructionist Judaism's first cantor in 2002. She earned a Bachelor of Music from the Indiana University Jacobs School of Music. Hordes now serves Keneseth Israel as their cantor.

Hordes was a presenter at the Jewish Reconstructionist Federation convention in 2004.

References

Year of birth missing (living people)
Living people
Hazzans
Women hazzans
American Jews
Jacobs School of Music alumni
The LeapPad Explorer was the first release in a new line of LeapPad products after the discontinuation of the original LeapPad line by LeapFrog Enterprises, Inc. LeapPad Explorer was released on August 15, 2011.

New versions of the LeapPad Explorers were released in July 2012. The update was branded the LeapPad2 and has a higher resolution camera, longer battery life, 4 GB of storage and a LF 2000 processor.

LeapPad Explorer specs
 Built-in 1.2 megapixel camera/video recorder
 5" touch screen (480x272)
 2 GB of storage

LeapPad2 specs
 Built-in 2.0 megapixel camera/video recorder
 4 GB of storage
 LF 2000 processor (550 MHz)

Awards
In 2012, the LeapPad Explorer was awarded 3 titles: "Toy of the Year (overall)", "Educational Toy of the Year" and "Preschool Toy of the Year" at the 12th Annual Toy of the Year Awards, which is held at the American International Toy Fair in New York City.

See also
 LeapFrog Epic, an Android-based tablet computer developed and marketed by LeapFrog

References

List of games licensed
Adventure Sketchers
Barbie
Blaze and the Monster Machines
Brave
Ben 10: Ultimate Alien
Bubble Guppies
Cars 2
Clifford the Big Red Dog
Crayola Art Adventure
Digging for Dinosaurs
Disney/Pixar Up
Disney Princess
Disney The Princess and the Frog
Doc McStuffins
Doodle Jump
Dora the Explorer: Dora’s Worldwide Rescue
Finding Dory
Frozen
The Good Dinosaur
Get Puzzled!
Globe: Earth Adventure
Hot Wheels
 Hello Kitty: Sweet Little Shops
I Spy
Jake and the Never Land Pirates
Jewel Train
Kidz Bop
LeapSchool Math
LeapSchool Reading
Letter Factory
Letter Factory Adventures: The Rainforest
The Little Mermaid
The Magic School Bus (Oceans, Dinosaurs, & Dino Shuffle)
Mini–Game Greatest Hits
Minnie Mouse Bowtique
Monsters University
Moshi Monsters
Mr. Pencil Saves Doodleburg
My Little Pony: Friendship is Magic
NFL Rush Zone
Ni Hao, Kai-Lan: Super Happy Day!
Octonauts
 Olivia
PAW Patrol
Pet Pals 2: Best of Friends
The Penguins Of Madagascar: Operation Plushy Rescue
Phineas and Ferb
Pixar Pals
Planes
Pocoyo
Scooby-Doo (Pirate Ghost of the Barbary Coast)
Sesame Street
SpongeBob SquarePants (Fists of Foam & The Clam Prix)
Star Wars (Jedi Reading & The Clone Wars)
Tangled
Team Umizoomi
Teenage Mutant Ninja Turtles
Tinkerbell & Lost Treasure
Toy Story 3
Transformers: Rescue Bots (Race to the Rescue)
Turbo
Wallykazam!
 Wolverine and The X-Men

External links
 LeapPad Explorer

2011 introductions
ARM-based video game consoles
Children's educational video games
Educational toys
Electronic toys
Embedded Linux
Tablet computers
Linux-based video game consoles
HyperZ is the brand for a set of processing techniques developed by ATI Technologies and later Advanced Micro Devices and implemented in their Radeon-GPUs. HyperZ was announced in November 2000 and was still available in the TeraScale-based Radeon HD 2000 Series and in current Graphics Core Next-based graphics products.

On the Radeon R100-based cores, Radeon DDR through 7500, where HyperZ debuted, ATI claimed a 20% improvement in overall rendering efficiency. They stated that with HyperZ, Radeon could be said to offer 1.5 gigatexels per second fillrate performance instead of the card's apparent theoretical rate of 1.2 gigatexels. In testing it was shown that HyperZ did indeed offer a tangible performance improvement that allowed the less endowed Radeon to keep up with the less efficient GeForce 2 GTS.

Functionality
HyperZ consists of three mechanisms:

 Z compression The Z-buffer is stored in a lossless compressed format to minimize the Z-Buffer bandwidth as Z read or writes are taking place. The compression scheme ATI used on Radeon 8500 operated 20% more effectively than on the original Radeon and Radeon 7500.
 Fast Z clear Rather than writing zeros throughout the entire Z-buffer, and thus using the bandwidth of another Z-Buffer write, a Fast Z Clear technique is used that can tag entire blocks of the Z-Buffer as cleared, such that only each of these blocks need be tagged as cleared. On Radeon 8500, ATI claimed that this process could clear the Z-Buffer up to approximately 64 times faster than that of a card without fast Z clear.
 Hierarchical Z-buffer This feature allows for the pixel being rendered to be checked against the z-buffer before the pixel actually arrives in the rendering pipelines. This allows useless pixels to be thrown out early (early Z reject), before the Radeon has to render them.

Versions of HyperZ
With each new microarchitecture, ATI has revised and improved the technology.
 HyperZ – R100
 HyperZ II – R200 (8500-9250)
 HyperZ III – R300 in Radeon 9700
 HyperZ III+ – R350 used in Radeon 9800, Radeon 9800 XL, Radeon 9800 Pro and Radeon 9800 SE
 HyperZ HD – R420 used in Radeon X700 to Radeon X850 XT PE

See also
 Rasterization
 Z-buffering
 Irregular Z-buffer
 Depth map

References

External links
  Anandtech's Preview of Radeon 256
 AMD press release about HyperZ

AMD technologies
ATI Technologies
Graphics cards
Michael Richard Brennan (born May 18, 1972) is a college basketball head coach who most recently served as head coach of American University and former professional European basketball player who played for teams in Germany, Belgium and Portugal. He previously served as an assistant coach for Columbia University, Georgetown University, Princeton University and American University. Brennan also holds an Irish passport.

Playing career 
Brennan won two Ivy League titles with the Princeton Tigers men's basketball. He played for the Tigers between 1990 and 1994, averaging 5.0 points, 2.4 rebounds and 1.7 assists per game. Professionally, he spent time in the German Basketball Bundesliga (at Bayer Leverkusen in 1996–97 and Braunschweig in 1997–98), Belgium (at Pepinster in 1998–99) and Portugal.

Assistant coaching career
Brennan was a volunteer assistant coach at Columbia University for one year then served as an assistant coach for Princeton University from 2000 to 2007. After being the assistant coach of Princeton, he became the assistant coach of AU from 2007 to 2009. The next four years he served as an assistant coach for Georgetown University. His overall record as an assistant coach was 252–163.

Head coaching career
Brennan was named the head coach of AU in April 2013.  In his first season with the Eagles, Brennan led them to a second place regular-season finish in the Patriot League, a Championship in the Patriot League Tournament, and a bid to the 2014 NCAA Tournament after being picked to finish just ninth in the Patriot League in the preseason poll. He was named 2014 Patriot League Coach of the Year based on this turnaround. On March 9, 2023, Brennan was fired following a March 5 double overtime loss in Patriot League semifinals.

Head coaching record

References

1972 births
Living people
American Eagles men's basketball coaches
American expatriate basketball people in Belgium
American expatriate basketball people in Germany
American expatriate basketball people in Portugal
American men's basketball coaches
American men's basketball players
Basketball Löwen Braunschweig players
Bayer Giants Leverkusen players
College men's basketball head coaches in the United States
Columbia Lions men's basketball coaches
Georgetown Hoyas men's basketball coaches
Guards (basketball)
Princeton Tigers men's basketball coaches
Princeton Tigers men's basketball players
RBC Pepinster players
Havidić Selo is a village in Croatia. It is formally a settlement (naselje) of Zagreb, the capital of Croatia.

Demographics
According to the 2021 census, its population was 63. According to the 2011 census, it had 53 inhabitants.

References

Populated places in the City of Zagreb
Frank Hunter and Elizabeth Ryan defeated the defending champions Leslie Godfree and Kitty Godfree in the final, 8–6, 6–0 to win the mixed doubles tennis title at the 1927 Wimbledon Championships.

Seeds

  Leslie Godfree /  Kitty Godfree (final)
  Jean Borotra /  Marguerite Bordes (second round)
  Frank Hunter /  Elizabeth Ryan (champions)
  Bill Tilden /  Molla Mallory (second round)

Draw

Finals

Top half

Section 1

Section 2

Bottom half

Section 3

The nationality of Mrs DM Evans is unknown.

Section 4

References

External links

X=Mixed Doubles
Wimbledon Championship by year – Mixed doubles
Notable people named James Bulger include:

 Whitey Bulger (1929–2018), organized crime boss and FBI informant
 James Bulger (1990–1993), English murder victim
The Estadio Victoria de Girón is a multi-use stadium in Matanzas, Cuba.  It is currently used mostly for baseball games and is the home stadium of Matanzas Cocodrilos.  The stadium holds 22,000 and was built in 1977.

References

Baseball venues in Cuba
Buildings and structures in Matanzas
Sports venues completed in 1977
20th-century architecture in Cuba
The following is a list of sovereign states and territories where Tamil is an official language or language of government.

Tamil is the 20th most spoken language in the world. Tamil language speakers make approximately 1.06% of the world population. Tamil language is native to Tamil Nadu (India) and Sri Lanka where most of the native Tamil speaking population is highly concentrated. Tamil was one of the prominent languages of trade in the region during the pre-colonial era. Tamil mercantile guilds like Ainnurruvar were active in Southeast Asia, and there are Tamil inscriptions and coins found in parts of Asia and Africa such as in China, Cambodia, Egypt and Indonesia.

During the 18th century, the British and French colonial rulers brought Tamils to many parts of Asia and Africa where many countries have sizeable number of Tamil speakers with significant cultural impact. There are more than 2,000,000 speakers of Tamil language in Malaysia itself. Tamil is recognized as a classical language by the Government of India and it is the first recognized classical language in India and it is also one of the 22 official languages in India.

Sovereign states

Dependent entities

Recognized as minority language

Partially recognized and unrecognized territories

Former dependent entities where Tamil was an official language

International institutions where Tamil is used

See also
 Tamil population per nation
 Tamil population by cities
 States of India by Tamil speakers
 Tamil Loanwords in other languages
 Tamil language
 Tamil people
 List of languages by first written accounts
 Tamil keyboard

Notes

References
The University of Kragujevac Faculty of Agronomy at Čačak (), located in Čačak, Serbia, is one of the educational institutions of the University of Kragujevac.

The school's programs cover agronomy, food technology, fruit picking, viticulture, zootechnics and other aspects of the agronomy studies.
The school offers undergraduate studies, Master degree studies, and doctoral studies.

History
The faculty began its operations on 9 October 1978. In 2018, it celebrated its 40-year anniversary.

Notable alumni
 Snežana Bogosavljević Bošković, Serbian politician

References

External links
 

University of Kragujevac
Agronomy schools
Business schools in Serbia
Čačak