Samantha912/NLP_A2_WTH huggingface dataset:
Kavalactones are a class of lactone compounds found in kava roots and Alpinia zerumbet (shell ginger). Kavalactones are under research for potential to have various psychotropic effects, including anxiolytic and sedative/hypnotic activities.

Enzyme inhibition
Kava extract has been shown in vitro to potentially inhibit a wide range of hepatic enzymes, suggesting a possible potential for interactions with many pharmaceuticals and herbal medications. In human volunteers in vivo inhibition is currently limited to CYP1A2, and CYP2E1 through use of probe drugs to measure inhibition.

Research 
Several preliminary studies are assessing potential effects of kava, including its anxiolytic actions and hepatotoxicity, but the role specifically of kavalactones among many other kava compounds for these effects remains under study.

The major kavalactones (except for desmethoxyyangonin) have been shown to potentiate the activity of GABAA receptors, which may underlie the anxiolytic and sedative properties of kava. Further, inhibition of the reuptake of norepinephrine and dopamine, binding to the CB1 receptor, inhibition of voltage-gated sodium and calcium channels, and monoamine oxidase B reversible inhibition are additional pharmacological actions that have been reported for kavalactones.

Kavalactone type compounds may help protect against high glucose induced cell damage.

Toxicity
Several kavalactones (e.g. methysticin and yangonin) affect a group of enzymes involved in metabolism, called CYP1A1. Hepatotoxicity occurred in a small portion of previously healthy kava users, particularly from extracts, as opposed to whole root powders.

Compounds 

At least 18 different kavalactones have been identified to date, with methysticin being the first identified.
Multiple analogues, such as ethysticin, have also been isolated.
Some consist of a substituted α-pyrone as the lactone while others are partially saturated.

The average elimination half-life of kavalactones typically present in kava root is 9 hr.

Biosynthesis
The kavalactone biosynthetic pathway in Piper methysticum was described in 2019.

See also
 Pipermethystine

References

External links
 
The great kava boom: how Fiji's beloved psychoactive brew is going global The Guardian, 2020

Monoamine oxidase inhibitors
 
GABAA receptor positive allosteric modulators
Anxiolytics
Analgesics
Sedatives
Anticonvulsants
Nootropics
Thaumatomonas is a genus within Imbricatea of the phylum Cercozoa.

It includes the species 
 Thaumatomonas coloniensis Wylezich et al. 2007
 Thaumatomonas constricta Scoble & Cavalier-Smith 2014
 Thaumatomonas hindoni (Nicholls 2012) Scoble & Cavalier-Smith 2014
 Thaumatomonas lauterborni de Saedeleer 1931
 Thaumatomonas oxoniensis Bass & Cavalier-Smith 2011
 Thaumatomonas seravini Mylnikov & Karpov 1993
 Thaumatomonas solis Scoble & Cavalier-Smith 2014
 Thaumatomonas vancouveri Cavalier-Smith & Chao 2011
 Thaumatomonas zhukovi Mylnikov 2003

References

Imbricatea
Cercozoa genera
Major-General Sir Wilsone Black  (10 February 1837 – 5 July 1909) was a British military officer and colonial administrator.

Military career
Black was commissioned into the 42nd Regiment of Foot in 1854. He served in the Crimea War from 1855 and was present at the Siege of Sebastopol. He was appointed a Brigade Major in Nova Scotia in 1867.

He transferred to the 6th Regiment of Foot in 1873 and to the 24th Regiment of Foot in 1875. He served in the 9th Xhosa War in 1877. He also served in the Anglo-Zulu War and was mentioned in despatches in 1879. He recovered the Queen's Colour of the 1st Bn of the 24th Regiment which had been lost in the Buffalo River after the Battle of Isandlwana.

He went on to be Commanding Officer of the South Wales Borderers in 1880, Assistant Adjutant and Quartermaster General in Nova Scotia in 1882, Assistant Adjutant General in Gibraltar in 1887, Commander of the Troops in Jamaica in 1891 and Commander in Belfast in 1893.

He became Commander of British Troops in China and Hong Kong in 1895 and was Acting Administrator in Hong Kong for a short period between February and November 1898.

He retired in 1899.

Family
In 1869 he married Florence Maud Ross; they had one daughter.

Memory 
Wilsone Black's life is commemorated on a memorial tablet in Brecon Cathedral.

Black Hill in Hong Kong was named after him.

References

1837 births
1909 deaths
Commanders of Hong Kong
British Army major generals
Military personnel from Glasgow
South Wales Borderers officers
Knights Commander of the Order of the Bath
42nd Regiment of Foot officers
British Army personnel of the Crimean War
British military personnel of the 9th Cape Frontier War
British Army personnel of the Anglo-Zulu War
Royal Warwickshire Fusiliers officers
Jo Bannister (born 31 July 1951 in Rochdale, Lancashire) is a British crime fiction novelist.

Life and work
She began her career as a journalist and rose to become editor of the County Down Spectator  before resigning to devote all her time to her writing. She has had over 30 novels published both in English and translated into several other languages. 
Most of these belong to five series, while nine are standalone novels. Her books are well reviewed, with the New York Times, for example, referring to her "solid series of British police procedurals", and praising the Castlemere novels for their "superb character work" in the context of a "deeply satisfying series".

Clio Rees and Harry Marsh novels
 Striving with Gods ( An Uncertain Death) (1984)
 Gilgamesh (1989)
 The Going Down of the Sun (1989)
 The Fifth Cataract (2005)

Mickey Flynn novels
 Shards (a.k.a. Critical Angle) (1990)
 Death and Other Lovers (1991)

Castlemere novels
 A Bleeding of Innocents (1993)
 Charisma (a.k.a. Sins of the Heart) (1994)
 A Taste for Burning (a.k.a. Burning Desires) (1995)
 No Birds Sing (1996)
 Broken Lines (1998)
 The Hireling's Tale (1999)
 Changelings (2000)

Rosie Holland novels
 The Primrose Convention (1997)
 The Primrose Switchback (2000)

Brodie Farrell novels
 Echoes of Lies (2001)
 True Witness (2002)
 Reflections (2003)
 The Depths of Solitude (2004)
 Breaking Faith (2005)
 Requiem for a Dealer (2006)
 Flawed (2007)
 Closer Still (2008)
 Liars All (2009)

Hazel Best & Gabriel Ash novels
 Deadly Virtues (2013)
 Perfect Sins (2014)
 Desperate Measures (2015)
 Other Countries (2017)
 Kindred Spirits (2018)

Standalone novels
 The Matrix (1981)
 The Winter Plain (1982)
 A Cactus Garden (1983)
 Mosaic (1986)
 The Mason Codex (a.k.a. Unlawful Entry) (1988)
 The Lazarus Hotel (1996)
 Tinderbox (2006)
 From Fire and Flood (2007)
 Fathers and Sins (2008)
 Death in High Places (2011)

References

1951 births
Living people
British crime writers
British journalists
Writers from Rochdale
Women mystery writers
Orthoceratium is a genus of flies in the family Dolichopodidae. Only two species are included in the genus, Orthoceratium lacustre and Orthoceratium sabulosum. They are known from the West Palaearctic and Tanzania.

In 2018, researchers Marc Pollet and Andreas Stark found that the species O. sabulosum in northwestern Europe had been misidentified as O. lacustre for over 250 years. This was explained by them as a result of previous authors copying identification keys with misleading information, the omission by those authors to study the type specimens of O. sabulosum, and the loss of those of O. lacustre.

Species
The following two species are included in the genus:
 Orthoceratium lacustre (Scopoli, 1763)
 Orthoceratium sabulosum (Becker, 1907)

References

Hydrophorinae
Dolichopodidae genera
Taxa named by Franz von Paula Schrank
Diptera of Europe
Diptera of Africa
Diptera of Asia
Vance W. Amory International Airport  serves the island of Nevis in the Federation of Saint Kitts and Nevis. The airport has a single runway, which is approximately 1,220 meters (4,000 feet) long. The airport is located just west of the village Newcastle, Nevis, in Saint James Windward Parish.

The airport was previously known as Bambooshay Airport, then Newcastle Airport. It was renamed in 2002 after the Premier of Nevis, Vance Amory, following the completion of a new, more modern terminal, a new control tower, and an extension to the runway. The airport is available to many aircraft, it being an international airport.

Airlines and destinations

Cargo

References

Airports in Saint Kitts and Nevis
Buildings and structures in Nevis
Derreen Ada Lucy Good (born 1904-) was an Irish badminton player.

Biography
Derreen Good was the daughter of badminton players Dr T. D. Good and Ada Good. Two of her siblings also played badminton at national and international level, Barbara and Norman. Good played her first international badminton match in 1928.

Achievements

References

1904 births
Date of death unknown
Irish female badminton players
Filipacchi is a surname. Notable people with the surname include:

Amanda Filipacchi (born 1967), American writer
Daniel Filipacchi (born 1928), the Chairman Emeritus of Hachette Filipacchi Médias

See also
Hachette Filipacchi Médias (HFM), the largest magazine publisher in the world
Hachette Filipacchi Media U.S. (HFM U.S.), subsidiary of Hachette Filipacchi Médias, based in New York City

Italian-language surnames
Patronymic surnames
Surnames from given names
Yeddanapudi is a mandal in the Bapatla district in the Coastal Andhra region of Andhra Pradesh, India. Its headquarters are in Yeddanapudi.

Demographics

As of 2011 census, the mandal had a population of 28,373 in 8,138 households. The total population constitutes 
13,417 males and 14,956 females — a sex ratio of 1115 females per 1000 males. 2,453 children are in the age group of 0–6 years, of which 1,280 are boys and 1,173 are girls — a sex ratio of 916 per 1000. The average literacy rate stands at 65.30% with 16,927 literates. Scheduled Castes and Scheduled Tribes make up 9,280 (32.71%) and 617 (2.17%) of the population respectively.

At the time of the 2011 census, 95.35% of the population spoke Telugu and 4.62% Urdu as their first language.

References

Mandals in Bapatla district
Jimmy Arthur Raye III (born November 24, 1968) is an American football former professional wide receiver and current team executive in the National Football League (NFL).

Early years
Raye is the son of Jimmy Raye II, who was the offensive coordinator for seven different NFL teams, most recently the San Francisco 49ers. He attended Irvine High School in Irvine, California during his high school years.

College career
A wide receiver for the Aztecs of San Diego State University (SDSU) from 1986 to 1990, Raye earned a bachelor's degree in public administration. He left SDSU tied for eighth on the school's all-time receiving list with 111 catches.

National Football League career
Raye's National Football League career began when he signed a free agent contract with the Los Angeles Rams in 1991. He ended up playing in the final two games of the season.

He was the offensive quality control coach for the Kansas City Chiefs in 1995. He joined the San Diego Chargers as a scout from 1996–1999, and served as the team's director of college scouting from 2000–2007. He was the Chargers' director of player personnel from 2008–2012.

In 2012, Chicago Bears general manager Jerry Angelo was fired, and Raye was one of four candidates for the job.

In 2013, Raye was hired as VP of Football Operations for the Indianapolis Colts, and held the post from 2013–2016.

In 2017, he was hired as VP of player personnel/assistant general manager for the Houston Texans.

In 2018, Raye was hired as Senior Personnel Executive for the Detroit Lions. On March 5, 2021, Raye parted ways with the Lions.

On June 16, 2022, Raye was hired by the Cleveland Browns as a senior executive advisor to the general manager.

References

External links
 Databasefootball.com playerpage RAYEJIM02
 Colts press release

1968 births
Living people
American football wide receivers
Los Angeles Rams players
San Diego State Aztecs football players
Players of American football from Fayetteville, North Carolina
Players of American football from Irvine, California
African-American players of American football
San Diego Chargers scouts
Houston Texans executives
Detroit Lions executives
Indianapolis Colts executives
San Diego Chargers executives
Kansas City Chiefs coaches
21st-century African-American people
20th-century African-American sportspeople
Yeoh Li Tian (born 1999) is a Malaysian chess player. He was awarded the title International Master by FIDE in 2017.

Chess career
Yeoh won the Malaysian Chess Championship in 2015 and 2016. In 2017 he won the FIDE Zone 3.3 Championship on tiebreak from Nguyễn Ngọc Trường Sơn. Thanks to this victory, Yeoh received an automatical award of the title International Master. He also achieved a norm for the title Grandmaster, the first ever by a Malaysian, and became the first Malaysian ever to qualify to play in the FIDE World Cup. In this latter event, held in Batumi later in the same year, Yeoh was eliminated by former world champion Viswanathan Anand in the first round.

In the 2019 Philippines Southeast Asian Games, Yeoh delivered Malaysia's first ever Rapid Chess gold in the Sea Games.

Personal life 
Yeoh is a former student of SMJK Katholik. He is currently studying mathematics at Imperial College London.

References

External links 
 
 Yeoh Li Tian chess games at 365Chess.com
 

1999 births
Living people
Chess International Masters
Malaysian chess players
SEA Games gold medalists for Malaysia
Competitors at the 2019 SEA Games
Place of birth missing (living people)
21st-century Malaysian people
Taavi Tamminen (10 March 1889 – 19 January 1967) was a Greco-Roman wrestler from Finland. He won a silver Olympic medal in 1920, losing in the final to his clubmate Emil Väre, a world title in 1921, and a national title in 1922. After retiring from competitions he worked as a wrestling referee and masseur, attending the 1936 Summer Olympics with the Finnish team.

References

External links
 

1889 births
1967 deaths
People from Uurainen
Olympic wrestlers for Finland
Wrestlers at the 1920 Summer Olympics
Finnish male sport wrestlers
Olympic silver medalists for Finland
Olympic medalists in wrestling
Medalists at the 1920 Summer Olympics
World Wrestling Championships medalists
Sportspeople from Central Finland
19th-century Finnish people
20th-century Finnish people
Laura Williams is an American politician who has served in the Kansas House of Representatives from the 30th district since January 9, 2023. She ran for the seat in 2020, but lost to democratic opponent Brandon Woodard. She owns Wilde Creative Company, a digital marketing agency.

References 

Living people
Republican Party members of the Kansas House of Representatives
21st-century American politicians
21st-century American women politicians
Women state legislators in Kansas
Politicians from Houston
University of Kansas alumni
M. Gail Hamner (born 1963) is an American scholar, author, and a professor at Syracuse University. Hamner is a Professor of Religion, while also an affiliate in the Faculty of Women and Gender Studies and Film and Screen Studies. She is the author of American Pragmatism: A Religious Genealogy.

Education 
Hamner attended Duke University where in 1985 she received her Undergraduate Bachelor of Science in Biology. She then went on to complete her Masters of Philosophical Theology at Boston University School of Theology in 1989 and her Ph.D in Religion in 1997 at Duke University.

Career 
Hamner worked as a Lecturer for the Department of Religion at Duke University from 1997–1998 before becoming an Assistant Professor for the Department of Religion at Syracuse University until 2005. Hamner became an Associate Professor of Religion in 2005 before becoming a full Professor at Syracuse University in 2013. In 2008, she became affiliated with the faculty of Women and Gender Studies at Syracuse University. As of 2015, she is affiliated with the faculty of Film and Screen Studies.

Since 2014 Hamner has been the Co-Chair of the American Academy of Religion (AAR) in the field of "Religion and Media Workshop" She is a member of The International Merleau-Ponty Circle, which focuses on the theory of philosophy.

Books and publications 
Hamner published her first book, American Pragmatism: A Religious Genealogy, in 2003 arguing about the uniqueness of pragmatism in America in relation to theology. The book garnered reviews in academic journals including The Journal of Religion, Transactions of the Charles S. Peirce Society, Journal of the American Academy of Religion, and Choice.

In 2012, Hamner published her second book, Imaging Religion in Film: The Politics of Nostalgia, where she examines the ethico-political dimensions of religion and film which was reviewed in the journal Anglican and Episcopal History. and is currently in the process of writing her third book, Public Affect: The Affective Dynamics of Religion in our Global 'public sphere' as felt through the Sci-Fi Feminine. Her most noted publication is Akira Kurosawa: "What is a Thing?"; Posing the Religious in Dress Uzala.

Controversy 
In 2016, Hamner faced backlash for not playing an Israeli film in front of her students and colleagues at a conference for "The Place of Religion in Film." Due to ongoing issues in the Middle East and BDS movements in Syracuse, Hamner emailed filmmaker Shimon Dotan about her reluctance to show his documentary, "The Settlers", due to certain groups boycotting Israel at Syracuse University. She issued a public apology through the Syracuse University following the controversy.

References 

1963 births
Living people
American religion academics
Duke University alumni
Boston University School of Theology alumni
Syracuse University faculty
20th-century American women writers
21st-century American women writers
20th-century American non-fiction writers
21st-century American non-fiction writers
American women non-fiction writers
American women academics
Rory is a unisex given name of Gaelic origin.

Rory may also refer to:

 Rory (band), an American band
 RORY, ICAO airport code for Yoron Airport, Yoronjima, Japan
 Rory, a blue lion who sang and played guitar in the ITV children's series Animal Kwackers
 RØRY, stage name for Roxanne Emery, London-based singer-songwriter

See also 
 Raury (born 1996), American musician
 Rori (disambiguation)
Frank George Griffith Carr (23 April 1903 – 9 July 1991) CB, CBE, MA, LLB, FSA, was director of the National Maritime Museum, Greenwich, England from 1947 to 1966 and was responsible for restoring and preserving a large number of ships, such as the Cutty Sark and the Gypsy Moth IV. After retirement he was involved in the creation of the Maritime Trust and the World Ship Trust which served the purpose of preserving old ships.

Life 
Frank Carr fell in love with sailing barges as a boy of 10. He acquired his first boat, a skiff-dinghy, in 1918. He used this vessel, the Maud, to explore the broads, fens and estuaries of East Anglia.

He was educated at The Perse School and Trinity Hall, Cambridge. While he was studying for his law degree at Cambridge, his first job was on a barge travelling between Ipswich and Antwerp in 1928. On graduation, he became assistant librarian at the House of Lords Library. He began research for his first book, Sailing Barges, published in 1931.

He continued sailing and his book A Yachtsman's log tells of the voyages made to the Baltic, Spain, and the British coastline in his Bristol Channel Pilot Cutter Cariad.

After serving in the RNVR during the Second World War, he was appointed director of the National Maritime Museum in 1946 where he supervised and oversaw its growth while also incorporating a number of other historic parts of Greenwich. He resigned from the museum in 1966 in controversial circumstances.

He served on the council of the Society for Nautical Research and was made its Honorary Vice-President.

He was a founder and chairman of the World Ship Trust (1978) and largely responsible for the survival of the Cutty Sark.

Carr was awarded the CBE (1954) and was made a CB (1967).

He died 9 July 1991, survived by his wife Ruth. A memorial service was held in the chapel of the Old Royal Naval College, Greenwich in October.

Publications 
Sailing Barges (1931, 5th edition 1989)
Vanishing craft (1934)
A Yachtsman's log (1935)
Yacht master’s guide and coastal companion (1940)
The Cutty Sark and the days of sail (c1962)
Maritime Greenwich (1974)
Gypsy Moth IV (c1981)

References 

1903 births
1991 deaths
Directors of the National Maritime Museum
Academics of the Royal Naval College, Greenwich
Alumni of Trinity Hall, Cambridge
People educated at The Perse School
British maritime historians
Companions of the Order of the Bath
The DG postcode area, also known as the Dumfries and Galloway postcode area, is a group of fifteen postcode districts in south-west Scotland, within fourteen post towns. These cover most of Dumfries and Galloway, including Dumfries, Annan, Canonbie, Castle Douglas, Dalbeattie, Gretna, Kirkcudbright, Langholm, Lockerbie, Moffat, Newton Stewart, Sanquhar, Stranraer and Thornhill. The DG16 district also extends across the border into Cumbria, England.



Coverage
The approximate coverage of the postcode districts:

|-
! DG1
| DUMFRIES
| Ae, Locharbriggs, Carrutherstown
| Dumfries and Galloway
|-
! DG2
| DUMFRIES
| New Abbey
| Dumfries and Galloway
|-
! DG3
| THORNHILL
| Moniaive
| Dumfries and Galloway
|-
! DG4
| SANQUHAR
| Sanquhar, Kirkconnel, Kelloholm, Mennock
| Dumfries and Galloway
|-
! DG5
| DALBEATTIE
| Dalbeattie
| Dumfries and Galloway
|-
! DG6
| KIRKCUDBRIGHT
| Kirkcudbright, Twynholm, Borgue, Dundrennan
| Dumfries and Galloway
|-
! DG7
| CASTLE DOUGLAS
| Castle Douglas, Gatehouse of Fleet, New Galloway
| Dumfries and Galloway
|-
! DG8
| NEWTON STEWART
| Newton Stewart, Wigtown, Port William, Glenluce, New Luce
| Dumfries and Galloway, South Ayrshire
|-
! DG9
| STRANRAER
| Stranraer, Castle Kennedy, Portpatrick, Sandhead
| Dumfries and Galloway
|-
! DG10
| MOFFAT
| Moffat, Beattock, Newton Wamphray
| Dumfries and Galloway
|-
! DG11
| LOCKERBIE
| Lockerbie, Johnstonebridge, Boreland, Ecclefechan, Kirtlebridge, Kirkpatrick-Fleming
| Dumfries and Galloway
|-
! DG12
| ANNAN
| Annan, Cummertrees, Brydekirk, Eastriggs
| Dumfries and Galloway
|-
! DG13
| LANGHOLM
| Langholm, Bentpath, Eskdalemuir, Arkleton
| Dumfries and Galloway
|-
! DG14
| CANONBIE
| Canonbie
| Dumfries and Galloway
|-
! DG16
| GRETNA
| Gretna, Gretna Green
| Dumfries and Galloway, Carlisle
|}

Map

See also
List of postcode areas in the United Kingdom
Postcode Address File

References

External links
Royal Mail's Postcode Address File
A quick introduction to Royal Mail's Postcode Address File (PAF)

Postcode areas covering Scotland
Gabriela Torres Olivares (born 1982) is a Mexican novelist and short story writer.

Biography 
Gabriela Torres Olivares has published four books of short stories and one novel. Her fictional work deals with the body and has been described as pertaining to the modern Mexican Gothic. Aside from the books she has published, her work has been included in numerous anthologies and literary journals. Her writing has been translated into Italian, French and English, and has been published in numerous literary publications in Mexico and internationally.

From 2004 to 2005, Torres Olivares was a fellow at the Centro de Escritores de Nuevo León, and from 2015 to 2016, she was the recipient of a grant from the Programa Jóvenes Creadores from the Mexican National Endowment for Culture and the Arts / FONCA. In 2017, her novel Piscinas Verticales won the Premio Binacional de Novela Joven Frontera de Palabras|Border of words from the Secretaría de Cultura and the Tijuana Cultural Center (CECUT).

Books 

 2004 – Están Muertos, Harikiri Plaquettes (short stories)
 2007 – Incompletario, Ediciones Intempestivas  (short stories)
 2010 – Enfermario, Fondo Editorial Tierra Adentro (short stories)
 2017 – Enfermario, Les Figues Press, (short stories) Spanish/English bilingual edition, translation by Jennifer Donovan.

References 

Mexican women short story writers
Mexican LGBT novelists
Mexican short story writers
21st-century Mexican writers
Writers from Monterrey
21st-century Mexican women writers
1982 births
Living people