Samantha912/NLP_A2_WTH huggingface dataset:
Ring chromosome 14 syndrome is a very rare human chromosome abnormality. It occurs when one or both of the telomeres that mark the ends of chromosome 14 are lost allowing the now uncapped ends to fuse together forming a ring chromosome. It causes a number of serious health issues.

Symptoms and signs
The most common symptoms are intellectual disability and recurrent seizures developing in infancy or early childhood. Typically the seizures are resistant to treatment with anti-epileptic drugs. Other symptoms may include:
 Microcephaly
 Lymphedema
 Facial abnormalities
 Immune deficiencies
 Abnormalities of retina
 Slow growth
 Short stature

Cause

The syndrome is caused by the loss of genetic material near the end of the long arm (q) of chromosome 14 . The break that causes the telomere(s) to be lost occurs near the end of the chromosome, and is called a constitutional ring. These rings arise spontaneously ( it is rarely inherited).

The genetic abnormality occurs randomly in sperm or egg cells or it may occur in early embryonic growth, if it occurs during embryonic growth the ring chromosome may be present in only some of a person's cells.

Diagnosis
Diagnosis is achieved by examining the structure of the chromosomes through karyotyping; while once born, one can do the following to ascertain a diagnosis of the condition:
 MRI
 EEG

Management

In terms of the management of ring chromosome 14 syndrome, anticonvulsive medication for seizures, as well as, proper therapy to help prevent respiratory infections in the affected individual are management measures that can be taken.

Epidemiology
Ring chromosome 14 syndrome is extremely rare, the true rate of occurrence is unknown (as it is less than 1 per 1,000,000), but there are at least 50 documented cases in the literature.

See also
 Ring chromosome 18 syndrome
 Ring chromosome 20 syndrome

References

Further reading

External links 

Congenital disorders
Rare diseases
Syndromes
Genetic disorders with no OMIM
Ring chromosomes
Austin Johnson (born June 16, 1989) is a former American football fullback. He played college football at Tennessee and attended Hickory High School in Hickory, North Carolina.

Early years
Johnson played football and baseball at Hickory High School in Hickory, North Carolina. He was an all-state selection for football in 2006 and 2007. He recorded 692 rushing yards and 18 rushing touchdowns on 108 attempts his senior year. Johnson also recorded 35 receptions and 470 receiving yards. He finished his high school career with 580 tackles.

College career
Johnson played for the Tennessee Volunteers from 2008 to 2011. He was an Academic All-SEC selection in 2008, 2009, and 2010.

Professional career

Baltimore Ravens
Johnson was signed by the Baltimore Ravens of the NFL on April 29, 2012 after going undrafted in the 2012 NFL Draft.

New Orleans Saints
Johnson signed with the NFL's New Orleans Saints on January 7, 2013. He was released by the Saints on August 31, 2013. He was signed to the Saints' practice squad on September 4, 2013. He made his NFL debut on September 7, 2014 against the Atlanta Falcons. Johnson suffered a knee injury in the Saints' Week 8 game against the Green Bay Packers; on November 4, 2014, the Saints placed him on the injured reserve list, ending his season. He was released by the Saints on November 3, 2015 and signed to the team's practice squad on November 5, 2015. He was promoted to the active roster on December 9, 2015. He was resigned on February 10, 2016. On September 3, 2016, he was waived by the Saints. Johnson was then signed to the Saints' practice squad the next day. He was released by the team on September 13, 2016.

Tampa Bay Buccaneers
On December 14, 2016, Johnson was signed to the Tampa Bay Buccaneers' practice squad. He was promoted to the active roster on December 28, 2016. He was waived on September 2, 2017, and was signed to the Buccaneers' practice squad the next day. He was released on October 10, 2017. He was re-signed to the practice squad on December 20, 2017. He signed a reserve/future contract with the Buccaneers on January 3, 2018.

On September 1, 2018, Johnson was waived by the Buccaneers.

References

External links
New Orleans Saints bio

Living people
1989 births
American football fullbacks
American football linebackers
Tennessee Volunteers football players
Baltimore Ravens players
New Orleans Saints players
Tampa Bay Buccaneers players
Players of American football from North Carolina
People from Hickory, North Carolina
Liga Deportiva Universitaria de Quito's 2022 season was the club's 92nd year of existence, the 69th year in professional football, and the 61st in the top level of professional football in Ecuador.

Club

Personnel
President: Guillermo Romero
President of the Executive Commission: Esteban Paz
Sporting manager: Santiago Jácome

Coaching staff
Manager: Luis Zubeldía
Assistant manager: Maximiliano Cuberas, Carlos Gruezo
Physical trainer: Lucas Vivas
Goalkeeper trainer: Luis Preti

Kits
Supplier: Puma
Sponsor(s): Banco Pichincha, Mazda, Universidad Indoamérica, Discover, Pilsener, Ecuabet, Salud SA

Squad information

Note: Caps and goals are of the national league and are current as of the beginning of the season.

Winter transfers

Summer transfers

Competitions

Pre-season friendlies

LigaPro

The 2022 season was Liga's 61st season in the Serie A and their 21st consecutive.

First stage

Results summary

Results by round

Second stage

Results summary

Results by round

CONMEBOL Sudamericana

L.D.U. Quito qualified to the 2022 CONMEBOL Sudamericana—their 13rd participation in the continental tournament—as 6th place in the 2021 LigaPro. They entered the competition in the First Stage.

CONMEBOL Sudamericana squad

First stage

Group stage

Copa Ecuador

L.D.U. Quito entered the competition in the Round of 32.

Round of 32

Round of 16

Player statistics

Note: Players in italics left the club mid-season.

Team statistics

References

External links
  

2022
2022 in Ecuadorian football
A waypoint is an intermediate point or place on a route or line of travel, a stopping point or point at which course is changed.

Waypoint may also refer to:
Waypoint, a defunct online property of Vice Media
Waypoint Centre for Mental Health Care, a mental health hospital in Canada
Waypoint Media, a confederation of holding companies
is a 2012 Japanese horror film directed by Kazuyoshi Hayashi.

Cast
Ami Yokota as Tomoko Takayanagi
Nako Mizusawa as Miu Kuroe

References

External links
Official website  

2012 horror films
Japanese horror films
2012 films
2010s Japanese films
John Fairbairn may refer to:
 Jock Fairbairn ( 1890s), Scottish football goalkeeper with Heart of Midlothian
 John Fairbairn (writer), English political journalist, author and translator
 John Fairbairn (Horticulturist), Curator of Chelsea Physic Garden 1784–1814
 John Fairbairn (educator) (1794–1854), newspaper proprietor, educator, financier and politician
 John Fairbairn, prisoner on St. Michael of Scarborough
 John Fairbairn (skeleton racer) (born 1983), Canadian skeleton racer
 John Fairbairn (naval officer) (1912–1984), South African naval officer who annexed the Prince Edward islands for South Africa
 Kaʻimi Fairbairn, full name John Christian Kaʻiminoeauloamekaʻikeokekumupaʻa Fairbairn (born 1994), American football player
Gymnoscyphus ascitus is a small species of clingfish found in the Caribbean Sea (documented off of Cuba (Jardines del Rey archipelago), Cozumel and St. Vincent) at depths of . This species is the only known member of the genus Gymnoscyphus.

References

Gobiesocidae
Fish of the Lesser Antilles
Fauna of Cozumel
Fish of Cuba
Fauna of Saint Vincent and the Grenadines
Monotypic ray-finned fish genera
Fish described in 1970
Sylvia Coleridge (10 December 1909 – 31 May 1986) was a British stage, film, radio and television actress.  Her credits included  Tess (1979), The Avengers, Dixon of Dock Green, The Onedin Line, Survivors, Blake's 7, The Tomorrow People, Z-Cars, Doctor Who,  Shoestring, Angels, Rumpole of the Bailey, and Bleak House in 1985.

Life
Coleridge was born on 10 December 1909 in Darjeeling, British India, now India. She died on 31 May 1986, in London. She was married to Albert George Fiddes-Watt, and they had daughter Kate, born 1943, who is also an actress as Kate Coleridge.

Career
After her stage debut in 1931, her theatre work included appearances at The Old Vic, the Malvern Festival and with the Royal Shakespeare Company. 

Her television acting credits include: Out of the Unknown, The Avengers, Paul Temple, The Lotus Eaters, Ace of Wands, The Tomorrow People, Z-Cars, Public Eye, Sutherland's Law, Dixon of Dock Green, The Onedin Line, Survivors,  Armchair Thriller (in the serial Quiet as a Nun), Blake's 7 (in the episode Gambit as the Croupier), Shoestring, The Flipside of Dominick Hide, Angels, Funny Man, Rumpole of the Bailey, Artemis 81, Bleak House,  and the sitcom Maggie and Her. 

Coleridge made a guest appearance in the Doctor Who serial The Seeds of Doom (1976). Tom Baker mentioned on the "Special Edition" DVD commentary for The Robots of Death that he had been so taken with Coleridge's eccentric performance in the serial that he had later suggested her as the new Doctor Who companion to producer Graham Williams.

Filmography

References

External links

Performances listed in the Theatre Archive University of Bristol

1909 births
1986 deaths
20th-century British actresses
20th-century English people
20th-century English women
Actresses from London
British film actresses
British radio actresses
British stage actresses
British television actresses
Sylvia
People from Darjeeling
Ludwig Marxer (27 April 1897 – 20 February 1962) was an advocate and political figure from Liechtenstein who served as the Deputy Prime Minister of Liechtenstein from 1928 to 1933.

Early life 
Marxer was born on 27 April 1897 in Eschen as one of eight children. His father by the same name was mayor of Eschen until 1898, when he and his family moved to Vaduz. Marxer attended high school in Feldkirch and then studied law and political science at the University of Innsbruck from 1922 to 1924.

Career 
He founded his own law firm Marxer & Partner Rechtsanwälte in 1925, as of May 2023 this is the oldest and largest law firm in Liechtenstein.

Marxer entered politics as a member of the Progressive Citizens' Party and remained so from 1928 to 1945. He had a friendship with Josef Hoop and was appointed to serve Deputy Prime Minister of Liechtenstein on 4 August 1928, the same day Hoop himself became Prime Minister of Liechtenstein. He resigned this position in 1933 due to his desire to focus on his law practice and was succeeded by Anton Frommelt. He remained a government advisor to Hoop for the rest of his premiership and officially resigned all government positions upon Hoop's resignation in 1945. A number of his clients and business partners were Jewish, which made him a target of attacks by the German National Movement in Liechtenstein (VBDL). On 16 June 1940 his house was the subject of a bombing attack.

From 1937 he served in the Princely judicial council then in the Staatsgerichtshof from 1960.

Marxer died of a stroke on 20 February 1962 at the age of 64 years old. His son Peter Marxer took over his firm Marxer & Partner Rechtsanwälte upon his death.

Family 
Marxer married Maria nee Öhri (29 May 1907 – 17 March 1962) in 1932 and they had three children, including Peter Marxer who took over his law firm and was also a politician in the Progressive Citizens' Party.

References 

Heads of government of Liechtenstein
Progressive Citizens' Party politicians
University of Innsbruck alumni
1897 births
1962 deaths
Alan Mannix (born 9 May 1947) is a former Australian rules footballer who played with Footscray in the Victorian Football League (VFL).

Career

Footscray
Mannix, a wingman and half forward, was 17 years old when he debuted for Footscray in the 1965 VFL season, after coming to the club from Crib Point. Although he never played a VFL final, he was a member of the Footscray team that won the night premiership in 1967. He celebrated his 100th league game in 1971, against Fitzroy, but was injured in the third quarter and required an operation for a lacerated kidney.

VFA
Following his eighth and final VFL season in 1972, Mannix left to play in the Victorian Football Association (VFA). Mannix went to Coburg with a clearance, paying the $500 transfer fee out of his own pocket.

Mannix played 110 games for Coburg, making him one of a small group of players to play more than 100 games for a VFL club and a VFA club. He won a 2nd Division premiership in 1974, finished third in voting for the 1975 J. J. Liston Trophy, won the club's best and fairest award twice, in 1973 and 1976, then was rewarded with the captaincy in 1977.

He also won a best and fairest for Werribee, in 1979. The following year he captain-coached Werribee for the season.

Coburg named Mannix on a wing in the club's  Team of the Century.

References

External links

1947 births
Australian rules footballers from Victoria (state)
Western Bulldogs players
Coburg Football Club players
Werribee Football Club players
Werribee Football Club coaches
Living people
Vlahovo may refer to the following places:

 Vlahovo, Bulgaria, village in Smolyan Province, Bulgaria
 Vlahovo (Svrljig), village in the municipality of Svrljig, Serbia
 Vlahovo (Žitorađa), village in the municipality of Žitorađa, Serbia
A list of films produced in Brunei from the earliest film to present. Films are listed by year of release.

1968-2017

References

Brunei
Valentín Larralde (born 15 November 2000) is an Argentine professional footballer who plays as a midfielder for San Martín de Tucumán of Primera Nacional.

Career
Larralde spent his embryonic years with a local team in El Pato, which preceded a two-year stint with Independiente and subsequently Gimnasia y Esgrima. In 2018, Larralde joined Defensa y Justicia. 2020 saw the central midfielder move into Hernán Crespo's first-team. He was initially an unused substitute for Copa Libertadores group stage wins over Delfín and Olimpia, before making his senior debut in the away match with Delfín on 1 October 2020; coming on for the final ten minutes of a three-goal defeat. Larralde signed his first professional contract a week later.

In June 2021, Larralde was loaned out to Arsenal Sarandí for the rest of 2021. After returning from the spell, he was loaned out again, this time to San Martín de Tucumán until the end of 2022.

Career statistics
.

Notes

References

External links

2000 births
Living people
People from Berazategui Partido
Argentine people of Basque descent
Argentine men's footballers
Argentine expatriate men's footballers
Men's association football midfielders
Argentine Primera División players
Defensa y Justicia footballers
Arsenal de Sarandí footballers
San Martín de Tucumán footballers
O'Higgins F.C. footballers
Chilean Primera División players
Expatriate men's footballers in Chile
Footballers from Buenos Aires Province
Otter Creek is a small unincorporated community in Pierce County, Georgia, United States, separating the cities of Patterson and Blackshear. The community includes a volunteer fire department, community center, and a popular restaurant also named "Otter Creek."

Unincorporated communities in Pierce County, Georgia
Unincorporated communities in Georgia (U.S. state)
Gavril A. Yushvaev (Russian: Гаврил Юшваев; born July 23, 1957) is Russian born Israeli businessman and investor known for the foundation of Wimm Bill Dann and investing in Polyus Gold. 

According to Forbes, Yushvaev's net worth as of 2023 is $1.9 billion.

Biography
Gavril Yushvaev was born in Makhachkala, Dagestan. He is certified by the Israeli Community of Porto as a descendant of Sephardic Jews.

In 1980, Yushvaev was convicted of robbery and spent nine years in a Soviet prison camp, according to Wimm-Bill-Dann's prospectus for its 2002 IPO. After his release in 1989, Yushavev partnered with David Yakobashvili. In 1993, they invested in the Lianozovo Dairy Plant, which later became Wimm Bill Dann. In 2020, he applied for Portuguese citizenship but, as of 2023, the process is still pending.

Business ventures 
Yushvaev became wealthy in the 1990s as the co-founder of Trinity which owned various businesses in Moscow. Yushvaev then invested in Wimm-Bill-Dann, a dairy and juice company. The company was founded in 1995 and had its initial public offering in 2002. Yushvaev was the company's largest shareholder until 2010, when he sold his 19.6% stake in the company to PepsiCo for $1.1 billion.

In 2013, Yushvaev, along with another Russian businessman, purchased a 38% stake in Polyus Gold from Mikhail Prokhorov for $3.6 billion. He sold his stake in Polyus Gold in 2015 and made a $100 million investment in Lyft in 2015 along with joining a consortium that invested $150 million in Humacyte in 2015, a US based biotechnology company. He has also invested in Delivery Hero in 2013, a German delivery service company, and Domo in 2018, a software company.

Yushvaev and Vladislav Doronin also invested $300 million in a large real estate project in Moscow in 2016. The developments included an 85 story office block, shopping center and parking space for nearly 4000 cars in Moscow city.

Yushvaev has a holding company in Cyprus.

Personal life
Yushvaev is married and has eight children.

References

Russian oligarchs
1957 births
Living people
Russian billionaires
Russian food industry businesspeople
People from Makhachkala
Russian businesspeople in Israel
Twinkling, also called scintillation, is a generic term for variations in apparent brightness, colour, or position of a distant luminous object viewed through a medium. If the object lies outside the Earth's atmosphere, as in the case of stars and planets, the phenomenon is termed astronomical scintillation; for objects within the atmosphere, the phenomenon is termed terrestrial scintillation. As one of the three principal factors governing astronomical seeing (the others being light pollution and cloud cover), atmospheric scintillation is defined as variations in illuminance only.

In simple terms, twinkling of stars is caused by the passing of light through different layers of a turbulent atmosphere. Most scintillation effects are caused by anomalous atmospheric refraction caused by small-scale fluctuations in air density usually related to temperature gradients. Scintillation effects are always much more pronounced near the horizon than near the zenith (directly overhead), since light rays near the horizon must penetrate a denser layer of and have longer paths through the atmosphere before reaching the observer. Atmospheric twinkling is measured quantitatively using a scintillometer. The effects of twinkling are reduced by using a larger receiver aperture; this effect is known as aperture averaging.

While light from stars and other astronomical objects is likely to twinkle, twinkling usually does not cause images of planets to flicker appreciably.
Stars twinkle because they are so far from Earth that they appear as point sources of light easily disturbed by Earth's atmospheric turbulence, which acts like lenses and prisms diverting the light's path. Large astronomical objects closer to Earth, like the Moon and other planets, encompass many points in space and can be resolved as objects with observable diameters. With multiple observed points of light traversing the atmosphere, their light's deviations average out and the viewer perceives less variation in light coming from them.

See also

 Adaptive optics
 Interplanetary scintillation
 Observational astronomy
 Twinkle, Twinkle, Little Star

References 

Observational astronomy
Atmospheric optical phenomena
Articles containing video clips
Two of Us is a 1987 gay-themed BBC television film written by Leslie Stewart and directed by Roger Tonge. It was produced for the BBC Schools Scene series, and intended for young adults.  It confronted the Thatcherite government's attempt to ban gay sex education in schools via the controversial (and since repealed) section 28 legislation. Given this backdrop, the BBC opted not to show it during the day and it was screened late at night, even though it was originally created for a school audience. It wasn't until February 1990 that the play was shown during the day.

Plot 
The film centres on the life of Phil, a fun loving student in his final year at British secondary school. He is currently going steady with girlfriend Sharon, whose best friend Vera (an early role for Kathy Burke) just happens to have the hots for his best mate Matthew. However, Matthew is gay, and dropped out of school the previous year as a means of escaping the abuse of the classroom, only for the discovery of his collection of soft-core gay porn to cause him problems at home as well. Matthew is an ardent swimmer – an opportunity for the film to immediately use and confront an obvious stereotype.

Phil is torn between the realisation that whilst he loves Sharon, he equally has feelings for Matthew.  He tries to have it both ways, introducing the one to the other – prompting Vera to describe him as a "little worm" when Sharon runs off in distress.  Tired of the complications of life at home, Phil and Matthew decide to elope to the coastal resort of Seaford on the Sussex coast.  Sharon follows him, determined to regain her "fella".

The film has two endings.  In the original 1987 release, Phil returns to Matthew at the beach, and they run together into the ocean.  The film was re-released in 1988 with an ending where Phil appears to leave with Sharon, but Matthew decides that life must go on and that he is his own person.

Cast

References

External links 
 
 
 

1987 television films
1987 films
1987 LGBT-related films
British LGBT-related television films
BBC Television shows
1980s English-language films
1980s British films
The 2017 Split local elections were held on 21 May and 4 June 2017 for the Mayor of Split and members of the Split city council. Ivo Baldasar, the 71st mayor who served from 2013 to 2017 ran for re-election to a second four-year term, ultimately finishing in 9th place with 0.80% of the vote in the first round. As no candidate won an absolute majority of the vote in the first round, a second round of elections was held on 4 June 2017 between the two highest-ranked candidates in terms of popular vote: Željko Kerum of the Croatian Civic Party, who was previously the 70th Mayor of Split from 2009 to 2013, and Andro Krstulović Opara of the Croatian Democratic Union. Krstulović Opara narrowly won the run-off taking 46.2% of the votes against 44.3% for Kerum. Turnout was 45.5% in the first round and 38.1% in the second round.

This was the third direct election for the mayor of Split (simultaneously held with elections for all other county prefects and mayors in Croatia) since the popular vote method was introduced in 2009, as previously those officials had been elected by their county or city assemblies and councils.

Mayoral election

Council election

See also
2017 Croatian local elections
List of mayors in Croatia
List of mayors of Split

References 

Split 2017
Split 2017
Split, Croatia
Split local
Split local
History of Split, Croatia