Miguel Ângelo Laporta Nicolelis, M.D., Ph.D. (, born March 7, 1961), is a Brazilian scientist, physician and Duke School of Medicine Professor in Neuroscience at Duke University, best known for his pioneering work surrounding brain-computer interface (also known as "brain-machine interface") technology.

Biography

Nicolelis holds a medical degree from the University of São Paulo (1984), a doctorate in Sciences (General Physiology) from the University of São Paulo (1989) and a PhD in Physiology and Biophysics from Hahnemann University (now Drexel University College of Medicine). He is a full professor in the Department of Neurobiology and Co-Director of the Neuroengineering Center at Duke University (USA). Founder of the Alberto Santos Dumont Association for Research Support (AASDAP) and the Santos Dumont Institute (ISD), he proposed the use of science as an agent of social and economic transformation. Nicolelis is a Researcher at the International Institute of Neurosciences Edmond and Lily Safra (IIN-ELS) and Coordinator of the Andar de Novo Project, developed at AASDAP in São Paulo.

He and his colleagues at Duke University implanted electrode arrays into a monkey's brain that were able to detect the monkey's motor intent and thus able to control reaching and grasping movements performed by a robotic arm. This was possible by decoding signals of hundreds of neurons recorded in volitional areas of the cerebral cortex while the monkey played with a hand-held joystick to move a shape in a video game. These signals were sent to the robot arm, which then mimicked the monkey's movements and thus controlled the game. After a while the monkey realised that thinking about moving the shape was enough and it no longer needed to move the joystick. So it let go of the joystick and controlled the game purely through thought. A system in which brain signals directly control an artificial actuator is commonly referred to as brain-computer interface ("BCI").

On January 15, 2008, Dr. Nicolelis lab saw a monkey implanted with a new BCI successfully control a  robot walking on a treadmill in Kyoto, Japan.  The monkey could see the robot, named CB, on a screen in front of him, and was rewarded for walking in sync with the robot (which was under the control of the monkey).  After an hour the monkey's treadmill was turned off, but he was able to continue to direct the robot to walk normally for another few minutes, indicating that a part of the brain not sufficient to induce a motor response in the monkey had become dedicated to controlling the robot, as if it were an extension of itself.

Nicolelis is a co-founder and scientific director of the Edmond and Lily Safra International Institute for Neuroscience of Natal, a brain research facility in Brazil.

On August 3, 2010, Nicolelis was awarded an NIH Director's Pioneer Award to continue his research on brain-machine interface technology. On January 5, 2011, Dr. Nicolelis was appointed by Pope Benedict XVI as an ordinary member of the Pontifical Academy of Sciences.

Nicolelis is a fan of Sociedade Esportiva Palmeiras, a Brazilian football club; a football ball with Palmeiras crest can be seen at his website. He is currently working on a project that allowed paraplegic Juliano Pinto, a 29-year-old with complete paralysis of the lower trunk to deliver the kickoff at the opening game of the 2014 FIFA World Cup, in Brazil.

Brain to brain
In 2013, a report of research by Nicolelis and others was published which showed brain to brain communication between two rats using brain–computer interfaces. This result may demonstrate the feasibility of a biological computer consisting of a network of animal, or human, brains.  Currently, researchers are divided on their views of this research. Critics state that there are flaws in the scientific methods used and that there is lack of controls. They claim that some of the scientific claims are rendered "far-fetched at best." One researcher stated the work was similar to a "poor Hollywood science fiction script." Proponents have praised this research for drawing attention to Brain to Brain Interfaces as a way of studying neural systems: “The study helps to promote the role of BMIs not only in prosthetic applications, but also as scientific tools. It's a contribution to that.”  Ron Frostig, a neuroscientist at the University of California, Irvine, has described this brain to brain work as "an amazing paper” and a “beautiful proof of principle” that information can be transferred from one brain to another in real time.

The True Creator of Everything

In August 10, 2020, the neuroscientist Nicolelis published his book entitled “The True Creator of Everything: How the Human Brain Shaped the Universe as We Know It.” It’s the third book of a trilogy that starts with the book “Muito Além do Nosso eu (portuguese version)” in 2011, and continues with “Made In Macaíba” published in 2016.
In this book, Nicolelis explores the thesis that the human brain would be the center of the universe and tries to explain the history, the culture and the human civilization based on recently discovered principles regarding human brain function: “The True Creator of Everything is a story about the creations of the human brain and the center position it should occupy in the cosmology of the universe.”
According to the author, the human mind works in a relative way, meaning that every movement is relative and the mind creates its own model of reality, which is constantly renewed with the information it obtains from the world. Such theory is called by Nicolelis as the “Theory of The Relativistic Brain.”
Building on his work with mathematician Ronald Cicurel, which they described in their 2015 monograph, he argues for a more center position for the human brain in other areas of scientific knowledge, beyond just neuroscience. Nicolelis takes inspiration from Ernst Gombrich's “The Story of Art”.

Further reading

Selected Publications on Brain-Machine Interfaces 
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References

External links 
  Nicolelis Lab
 CV and awards
 
 
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  International Institute for Neuroscience of Natal (IINN)
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 "Minds and Machines – A conversation with Miguel Nicolelis", Ideas Roadshow, 2013

1961 births
Living people
Brazilian neuroscientists
Brazilian people of Italian descent
Brain–computer interfacing
University of São Paulo alumni
Duke University faculty
Brazilian people of Greek descent
Members of the French Academy of Sciences
Brazilian expatriate academics in the United States
American people of Brazilian descent
Drexel University alumni
Recipients of the Grand Cross of the Order of Ipiranga