Samantha912/NLP_A2_WTH huggingface dataset:
Sharon Catherine Brown (born January 11, 1962), also known as Sharon Catherine Blanks, is an American actress of stage, film, and television.

Early life 
She was born in New York City and is the daughter of actor Johnny Brown, who portrayed Nathan Bookman on the 1970s sitcom Good Times. Her mother, June Brown, was a studio manager. Sharon graduated from Hollywood High School where she played Mame Dennis in the musical Mame and Ruth Sherwood in Wonderful Town. She has a brother, John Brown Jr.

Career 
Brown has worked frequently as a stage actress, including roles as Effie in both Broadway and touring productions of the musical Dreamgirls; as Violet in the musical Maggie Flynn; and as the narrator in versions of Joseph and the Amazing Technicolor Dreamcoat. She has also toured with productions of The Wiz, Rent and Jekyll & Hyde. Brown was nominated for a Helen Hayes Award in 1987 for Outstanding Lead Actress in a Non-Resident Production for her role in the touring version of Dreamgirls.

Film credits include A Chorus Line (1985), For Keeps (1988), Sister Act 2 (1993), What's Love Got to Do with It (1993), Blues Brothers 2000 (1998) and Introducing Dorothy Dandridge (1999). On television, Brown played the character Daisy on the CBS soap opera Love of Life in 1971, and she originated the role of Chantel on the NBC soap Generations from 1989 to 1990. She portrayed a young Louise in a 1981 flashback episode of The Jeffersons titled "And the Doorknobs Shined Like Diamonds". Other episodic television credits include Good Times, A Different World and The Fresh Prince of Bel-Air.

Personal life 
She married Billy Blanks Jr., the son of Tae Bo fitness personality Billy Blanks. They taught at fitness studios in Sherman Oaks, California, and developed a series of fitness videos.  In 2014, Blanks pitched the program to Shark Tank and accepted a deal.  They have an adopted son named Elijah. They are divorced.

Filmography

Film

Television

References

External links 

1962 births
Living people
Actresses from New York City
American soap opera actresses
American stage actresses
American film actresses
American television actresses
American exercise instructors
21st-century American actresses
Seismic wide-angle reflection and refraction is a technique used in geophysical investigations of Earth's crust and upper mantle. It allows the development of a detailed model of seismic velocities beneath Earth's surface well beyond the reach of exploration boreholes. The velocities can then be used, often in combination with the interpretation of standard  seismic reflection data and gravity data, to interpret the geology of the subsurface.

Theory
In comparison to the typical seismic reflection survey, which is restricted to relatively small incidence angles due to the limited offsets between source and receiver, wide-angle reflection and refraction (WARR) data are acquired with long offsets, allowing the recording of both refracted and wide-angle reflection arrivals.

Acquisition
The acquisition setup depends on the type of seismic source being used and the target of the investigation.

Source
The source of the seismic waves may be either "passive", e.g. naturally occurring sources, such as earthquakes, or anthropogenic sources, such as quarry blasts, or "active", sometimes referred to as "controlled source", e.g. explosive charges set off in shallow boreholes or seismic vibrators onshore or air guns offshore. Exceptionally, the sound waves from nuclear explosions have been used to look at the structure of the upper mantle down to the base of the transition zone at 660 km depth.

Receiver
The sound waves are normally recorded using 3-component seismometers, with ocean-bottom seismometers (OBS) used offshore. The three components allow the recording of S-waves as well as the P-waves that single component instruments can record. The offset range used depends on the depth of the target. For the top few kilometres of the crust, such as when investigating beneath a thick layer of basalt, a range of 10–20 km may be appropriate, while for the lower crust and mantle, offsets greater than 100 km are normally necessary.

Modelling
The processing approach used in standard seismic reflection profiling is not appropriate for wide-angle data. The main modelling approach used for WARR profiles is to match predicted travel times, based on the geology, with those observed in the data. An initial model of variations in seismic velocity is set up, based on whatever knowledge is available from other sources. A ray tracing algorithm is used to calculate the travel times and the model is adjusted iteratively to reduce the misfit between observed and modelled times. Most modelling uses P-waves, but S-waves are also modelled in some cases.

References

Geophysics
Plain Jane Automobile (often referred to PJA) is an American indie rock band based in Orlando, Florida, United States. They have existed as a band for the past seven or eight years, but reinvented themselves in 2005 with key new members, and have not changed the line-up since. The band's current line-up consists of James "Duke" Crider (vocals), Luis Mejia (guitar), Paul McCorkell (bass), and James Dickens (drums).

Summary 
Plain Jane Automobile began as a collaboration between Duke Crider and Luis Mejia. The pair's ability to write songs and drive their live shows led to their meeting Paul McCorkell and James Dickens.

In 2008, Plain Jane Automobile released The Collector. They also toured extensively throughout the United States with fellow indie rock band Ours, with guitar, vocal and keyboard tour support by Matt Vetter winning many new fans. In 2009, they planned another tour, as well as working on songs for a new album.

With the chemistry of the line-up solidified, everything fell into place. In 2005, the indie pop quartet won the 2005 DiscMakers Independent Showcase, hand-picked as the best of a series of bands by major A&R reps at Billboard magazine and TAXI (A&R).

In 2010 the band was working on the follow-up to The Collector. In March 2011, a series of promo videos for the new album, Your Tomorrow, were posted on Plain Jane Automobile's Facebook page. The first video was a 50 second clip of an unknown track on the new album, as well as the release date for the next album. The second video included a one-minute clip of Please Leave Quietly, a song from the new album. A third video was posted recently that was similar in nature to the first two videos. Your Tomorrow is slated for release on May 9, 2011.

Discography

Albums 
The Collector (2008, Rymo Records)
Your Tomorrow (2011)

EPs 
Plain Jane Automobile (2006, Eighth Dimension)

References

External links
Official Website
Local Spotlight: Plain Jane Automobile
Las Vegas Weekly: Events Calendar

Indie rock musical groups from Florida
Musical groups from Orlando, Florida
Frasera, the green gentians, is a genus in the gentian family, native to North America and named for John Fraser, a Scottish botanist and colleague of Thomas Walter.

Taxonomy
Historically, Frasera has sometimes been considered part of Swertia, but molecular analysis of a number of Frasera species has shown them to form a monophyletic clade separate from the rest of Swertia.

Species
 Frasera ackermaniae
 Frasera albicaulis
 Frasera albomarginata
 Frasera caroliniensis
 Frasera coloradensis
 Frasera fastigiata
 Frasera gypsicola
 Frasera montana
 Frasera neglecta
 Frasera puberulenta
 Frasera pahutensis
 Frasera paniculata
 Frasera parryi
 Frasera speciosa
 Frasera tubulosa
 Frasera umpquaensis

References

 
Flora of Northern America
Gentianaceae genera
Anne Cooke,  (née Syme; born 14 November 1945) is a British biologist and academic, specialising in immunology and autoimmune diseases. From 2000 to 2013, she was Professor of Immunobiology at the University of Cambridge. She was a fellow of King's College, Cambridge, between 1992 and 2013.

Early life
Cooke was born on 14 November 1945 in South Shields, England, to William and Margaret Syme. She studied biochemistry at the University of Glasgow and graduated with a Bachelor of Science (BSc) degree in 1967. She then undertook postgraduate research in biochemistry and immunology at the University of Sussex. She completed her Doctor of Philosophy (DPhil) degree in 1970. Her doctoral thesis was titled Characterisation of immunoglobulin synthesised by lymphoid tissue in vitro.

Academic career
Cooke began her academic career as a postdoctoral fellow. From 1970 to 1972, she held a SRC postdoctoral fellowship in the Department of Biochemistry at the University of Sussex. From 1972 to 1973, she was a postdoctoral fellow at the University of Illinois and worked at the Medical Center, Chicago, USA. From 1973 to 1978, she held an Arthritis Research UK postdoctoral research fellowship in the Immunology Department of Middlesex Hospital. Then from 1978 to 1981, while remaining at Middlesex Hospital, she was a Wellcome Trust senior research fellow.

In 1981, Cooke moved from research into teaching and research. From 1981 to 1988, she was a Wellcome Trust senior lecturer within the immunology division of the UCL Medical School and also at the Middlesex Hospital Medical School.  During this time she collaborated with Joyce Baird, diabetologist at Edinburgh's Western General Hospital.  From 1988 to 1990, she was Reader in Experimental Immunology at University College London.

In 1990, Cooke moved to the University of Cambridge. From 1990 to 1996, she was a lecturer in the Department of Pathology. In 1992, she was elected a fellow of King's College, Cambridge. From 1996 to 2000, she was reader in immunology. In 1999, she was a visiting professor at the University of Washington, Seattle. On 1 October 2000, she was granted a personal chair and appointed professor of immunobiology. In 2013, she retired from full-time academia; she was appointed professor emeritus and made an emeritus fellow of King's College.

Personal life
In 1969, the then Anne Syme married Jonathan Cooke. Together, they have two sons.

Honours
In 2007, Cooke was elected a Fellow of the Academy of Medical Sciences (FMedSci). On 18 November 2010, she was awarded an honorary doctorate by the University of Copenhagen. In 2011, she was elected a Fellow of the Royal Society of Biology (FRSB).

Selected works

References

1945 births
Living people
British women biologists
Women medical researchers
Fellows of King's College, Cambridge
Fellows of the Academy of Medical Sciences (United Kingdom)
Fellows of the Royal Society of Biology
People from South Shields
Alumni of the University of Glasgow
Alumni of the University of Sussex
Academics of the University of Sussex
University of Illinois faculty
Academics of University College London
British pathologists
The cuneiform sign mu, is a common-use sign of the Amarna letters, the Epic of Gilgamesh, and other cuneiform texts (for example Hittite texts). It is also used as MU.

Linguistically, it has the alphabetical usage in texts for m, or u, or syllabically for mu. The u is replaceable in word formation by any of the 4 vowels: a, e, i, or u.

One reason for the high usage of mu in the Amarna letters is for the word: "peace", or "be safe", Akkadian language šalāmu, for "to be sound, whole, safe". It is used especially between the Great King letters.

Epic of Gilgamesh usage
The mu sign usage in the Epic of Gilgamesh is as follows: mu-(266 times); MU-(87).

References

Moran, William L. 1987, 1992. The Amarna Letters. Johns Hopkins University Press, 1987, 1992. 393 pages.(softcover, )
 Parpola, 1971. The Standard Babylonian Epic of Gilgamesh, Parpola, Simo, Neo-Assyrian Text Corpus Project, c 1997, Tablet I thru Tablet XII, Index of Names, Sign List, and Glossary-(pp. 119–145), 165 pages.

Cuneiform signs
De Horst is a hamlet in the Netherlands and it is part of the Noordenveld municipality in Drenthe.

De Horst is not a statistical unit, and has been placed under the postal code for Peize. It contains about 20 houses. It has no place signs, and is indicated by the street signs. It was first mentioned in 1479 as "ter Horst gehieten inden karspele van Peyse" (the settled height in the community of Peize)

References 

Populated places in Drenthe
Noordenveld
Archibald Campbell Carlyle (1831–1897) was an English archaeologist active in India.

The Archaeological Survey of India was revived as a distinct department of the government and Sir Alexander Cunningham was appointed as Director General, taking office in February 1871. Cunningham was given two assistants: J. D. Beglar and Carlleyle. They were later joined by H. B. W. Garrik. Carlleyle handled the Agra region for the Report of 1871–72, while Beglar was responsible for Delhi.

In 1867–68, Carlleyle discovered paintings on the walls and ceilings of rock shelters in Sohagighat, in the Mirzapur district. He was the first to claim a Stone Age antiquity for these. He also made many other important contributions to archaeology in India. He is credited with finding of 20 copper and 4 silver punch-marked coins at Bahraich, near the ancient city of Benaras (modern Varanasi).

References

External links
 

1831 births
English archaeologists
19th-century Indian archaeologists
1897 deaths
A list of films produced in Spain in 1983 (see 1983 in film).

1983

External links
 Spanish films of 1983 at the Internet Movie Database

1983
Spanish
Films
Manuel Nicolás Carizza (born 23 August 1984 in Rosario) is an Argentine rugby union footballer who usually plays as a lock. He currently plays for French Top 14 side . He started his career with Argentine club Jockey Club de Rosario until he joined French side  in 2005. He spent seven years at Biarritz before joining  for the 2012–13 season. In 2014, he signed for South African Super Rugby side the  and also played for their affiliated domestic provincial side , but returned to Racing Métro (since rebranded as ) for the 2015–16 season.

He made his international debut for Argentina in December 2004 in a match against South Africa, which the Springboks won by 39 points to 7. He next played for the Pumas in April 2005, where he was called up to the starting line-up against Japan. He then played in the November Tests against the Springboks, Scotland and Italy.

He was capped in June 2006 in one of the Tests against Wales during the hosting of a two match series, which Argentina eventually won. He was capped against Chile and Uruguay in July, in the starting line-up for both games.

He signed for South African Super Rugby side the  for the 2014 Super Rugby season.

Honours
 Racing 92
Top 14: 2015–16

References

External links
 Manuel Carizza on ercrugby.com
 Manuel Carizza on lequipe.fr

1984 births
Sportspeople from Rosario, Santa Fe
Argentine rugby union players
Living people
Rugby union locks
Biarritz Olympique players
Racing 92 players
Stormers players
Argentina international rugby union players
Expatriate rugby union players in South Africa
Expatriate rugby union players in France
Argentine expatriate sportspeople in France
Argentine expatriate rugby union players
Courtney D. Fitzhugh is an American hematologist-oncologist and scientist. She is a clinical researcher and head of the laboratory of early sickle cell mortality prevention at the National Heart, Lung, and Blood Institute.

Life 
Fitzhugh was born in Los Angeles, California. completed a B.S. magna cum laude from the University of California, Los Angeles in 1996. She earned a M.D. from the University of California, San Francisco in 2001. During medical school, Fitzhugh participated in the National Institutes of Health (NIH) Clinical Research Training Program, where she studied with  at the National Heart, Lung, and Blood Institute (NHLBI). After completing her M.D., Fitzhugh completed a joint residency in internal medicine and pediatrics at Duke University Medical Center, and in 2005 she did a combined adult hematology and pediatric hematology-oncology fellowship at the NIH and Johns Hopkins Hospital.

Fitzhugh returned to the NHLBI in 2007 and was appointed as assistant clinical investigator in 2012 and clinical tenure track investigator in 2016. She is a Lasker clinical research scholar and heads the NHLBI laboratory of early sickle mortality prevention. Her laboratory researches sickle cell disease and hematopoietic stem cell transplantation.

Fitzhugh is a member of the American Society of Hematology.

References 

Living people
Date of birth missing (living people)
Scientists from Los Angeles
University of California, Los Angeles alumni
University of California, San Francisco alumni
American hematologists
American oncologists
21st-century African-American physicians
21st-century American women scientists
Physician-scientists
African-American women physicians
National Institutes of Health people
Women hematologists
Women oncologists
21st-century American women physicians
21st-century American physicians
21st-century African-American women
Year of birth missing (living people)
Come Fill the Cup is a 1951 film starring James Cagney and Gig Young, directed by Gordon Douglas. Young's performance was nominated for an Academy Award for Best Supporting Actor.

Cagney plays an alcoholic newspaperman. He has a memorable line, "Don't you see? I am home," in response to the query, "Why don't you go home?"  at two points in the film, once near the beginning when he is drinking; once at the end when he is at work.

Plot

Lew Marsh is a good newspaper reporter with a bad habit; he drinks too much and is fired. He also loses the woman he loves, colleague Paula Arnold, after passing out drunk one day in the street.

An ex-alcoholic, Charley Dolan, takes pity on Lew, offering him a room at his apartment and finding him a job with a construction crew. Lew is tempted to have a drink when he learns that Paula has married another man, Boyd Copeland, the nephew of Lew's former boss at the newspaper, John Ives.

Ives gives the newly sober Lew a second chance at the paper. Many months pass, during which time Lew not only remains sober but is helpful to others with the same weakness. This comes to the attention of Ives, who is worried about Boyd's increased drinking.

Lew learns that Boyd has been unfaithful to Paula, taking up with a singer named Maria who is loved by a jealous gangster named Garr. To help, Lew invites Boyd to come live with Charley and him. He also helps the lonely Paula return to work for the newspaper, secretly hoping that she will fall in love with him again.

Garr and a henchman rig a car in a bid to murder Boyd, but end up killing Charley by mistake. A depressed Boyd feels responsible and tries to commit suicide. Boyd gets in touch with Maria, but they are being followed by Garr and another thug. At gunpoint, Boyd and Lew are ordered to drink by Garr, who intends to make their murders look accidental, but they get the upper hand on Garr and it is the mobster who is killed.

Boyd is able to persuade Paula to give their marriage another try. Lew is pleased for them, satisfied to be sober and working again.

Cast
 James Cagney as Lew Marsh
 Gig Young as Boyd Copeland
 Phyllis Thaxter as Paula Arnold
 Raymond Massey as John Ives
 James Gleason as Charley Dolan
 Sheldon Leonard as Lennie Garr

Reception
The film earned an estimated $1.9 million in US theatrical rentals in 1951.

Awards and nominations

References

External links

Review of film at Variety

1951 films
1951 drama films
American drama films
American black-and-white films
Films about journalists
Films about alcoholism
Warner Bros. films
Films directed by Gordon Douglas
Films scored by Ray Heindorf
1950s English-language films
1950s American films
Epsilon Scuti, Latinized from ε Scuti, is a probable astrometric binary
 star system in the constellation Scutum. It is faintly visible to the naked eye with an apparent visual magnitude of +4.88. Based upon an annual parallax shift of 5.71 mas as seen from Earth,> it is located approximately 570 light years from the Sun. It is moving closer to the Sun with a radial velocity of −9.8 km/s. 
Epsilon Scuti was a latter designation of 3 Aquilae.

The visible component is a yellow-hued bright giant with a G-type bright giant It is radiating 403 times the Sun's luminosity from its photosphere at an effective temperature of 4,500 K. Epsilon Scuti has at least three faint visual companions, two 14th magnitude stars, B and D, separated from the primary by 13.6 and 15.4 arcseconds respectively, and the 13th magnitude C, which is 38 arcseconds away.

References

G-type bright giants
Astrometric binaries
Scuti, Epsilon
Scutum (constellation)
BD-08 4686
173009
091845
7032
TIC objects
Fosdenopterin (or cyclic pyranopterin monophosphate, cPMP), sold under the brand name Nulibry, is a medication used to reduce the risk of death due to a rare genetic disease known as molybdenum cofactor deficiency type A.

The most common side effects include complications related to the intravenous line, fever, respiratory infections, vomiting, gastroenteritis, and diarrhea.

Fosdenopterin was approved for medical use in the United States in February 2021,  It is the first medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of molybdenum cofactor deficiency type A. and in the European Union in September 2022. The US Food and Drug Administration considers it to be a first-in-class medication.

Medical uses 
Fosdenopterin is indicated to reduce the risk of mortality in people with molybdenum cofactor deficiency  (MoCD) type A.

Mechanism of action
People with molybdenum cofactor deficiency type A cannot produce cyclic pyranopterin monophosphate (cPMP) in their body. Fosdenopterin is an intravenous medication that replaces the missing cPMP. cPMP is a precursor to molybdopterin, which is required for the enzyme activity of sulfite oxidase, xanthine dehydrogenase/oxidase and aldehyde oxidase.

History 
Fosdenopterin was developed at the German universities TU Braunschweig and the University of Cologne.

The effectiveness of fosdenopterin for the treatment of MoCD-A was demonstrated in thirteen treated participants compared to eighteen matched, untreated participants. The participants treated with fosdenopterin had a survival rate of 84% at three years, compared to 55% for the untreated participants.

The U.S. Food and Drug Administration (FDA) granted the application for fosdenopterin priority review, breakthrough therapy, and orphan drug designations along with a rare pediatric disease priority review voucher. The FDA granted the approval of Nulibry to Origin Biosciences, Inc., in February 2021.

Society and culture

Legal status 
On 21 July 2022, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion, recommending the granting of a marketing authorization under exceptional circumstances for the medicinal product Nulibry, intended for the treatment of patients with molybdenum cofactor deficiency (MoCD) Type A. The applicant for this medicinal product is Comharsa Life Sciences Ltd. Fosdenopterin was approved for medical use in the European Union in September 2022.

References

External links 
 

Breakthrough therapy
Orphan drugs
Organophosphates
The chairman of the People's Khural of Kalmykia is the presiding officer of that legislature.

Chairmen of the Supreme Soviet

Chairman of the Temporary Parliament

Chairmen (Speakers) of the People's Khural of Kalmykia

Sources

Lists of legislative speakers in Russia
Chairmen