Samantha912/NLP_A2_WTH huggingface dataset:
v-Src is a gene found in Rous sarcoma virus (RSV) that encodes a tyrosine kinase that causes a type of cancer in chickens.

The src gene is oncogenic as it triggers uncontrolled growth in abnormal host cells. It was the first retroviral oncogene to be discovered. The src gene was taken up by RSV and incorporated into its genome conferring it with the advantage of being able to stimulate uncontrolled mitosis of host cells, providing abundant cells for fresh infection.

The src gene is not essential for RSV proliferation but it greatly increases virulence when present.

Discovery 

Francis Peyton Rous first proposed that viruses can cause cancer. He proved it in 1911 and was later awarded the Nobel prize in 1966. Chickens grow a tumor called a fibrosarcoma. Rous collected and ground up these sarcomas, and then centrifuged them to remove the solid material. Next, the remaining liquid mixture was injected into chicks. The chicks developed sarcomas. The causative agent in the liquid was a virus, this is now called the Rous sarcoma virus (RSV).

Function 

Further research done later on by others showed that RSV was a type of retrovirus. It was found that the v-Src gene in RSV is required for the formation of cancer.

A function for Src tyrosine kinases in normal cell growth was first demonstrated with the binding of family member p56lck to the cytoplasmic tail of the CD4 and CD8 co-receptors on T-cells. Src tyrosine kinases also transmit integrin-dependent signals central to cell movement and proliferation. Hallmarks of v-Src induced transformation are rounding of the cell and the formation of actin rich podosomes on the basal surface of the cell. These structures are correlated with increased invasiveness, a process thought to be essential for metastasis.

v-Src lacks the C-terminal inhibitory phosphorylation site (tyrosine-527), and is therefore constitutively active as opposed to normal Src (c-Src) which is only activated under certain circumstances where it is required (e.g. growth factor signaling). v-Src is therefore an instructive example of an oncogene whereas c-Src is a proto-oncogene.

The first sequence of v-Src was published in 1980 and the characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus and its normal cellular homologue was published in 1981.

See also 
 c-Src

References 

Oncogenes
Kristian Marthinsen Kulset (born 1 October 1995) is a Norwegian former cyclist, who competed as a professional from 2016 to 2022 for .

His brothers Sindre, Magnus and Johannes are also professional cyclists.

References

External links

1995 births
Living people
Norwegian male cyclists
Cyclists from Oslo
Henry Wandal Yager (bef May 12, 1802 – January 9, 1860) was a farmer, businessman and political figure in Upper Canada.

He was born in Claverack, Columbia County, New York, in 1802, the son of Wandal Yager and Eva Dings. The family moved to Upper Canada and settled in Thurlow Township, Hastings County, Ontario about 1800. He was not a United Empire Loyalist. He married Elizabeth White, daughter of Reuben White who was also elected to the Legislative Assembly of Upper Canada.

From the land records, it appears that he was an active speculator frequently buying and selling land in the area and is often referred to as a merchant in the deeds though no record of his business has been found. In 1834, Yager was elected to the 12th Legislative Assembly of Upper Canada session for Hastings. He was a reformer. Thirteen letters were saved by the family from his political years and are now held by the Archives of Canada and called the Henry W Yager Fonds.

In 1847, he left Canada and took his family to Wisconsin, where he bought a farm in Dane County, Wisconsin about 4 miles from Madison, near the home of his daughter Lorinda. He died in Dane County in 1860.

References 
 Becoming Prominent: Leadership in Upper Canada, 1791-1841, J.K. Johnson, McGill-Queen's Univ Press, (1989)
 The Rebels of Hastings, Betsy Dewar Boyce, University of Toronto Press, (1992)

External links 
“Henry W Yager of Thurlow Tp, Hastings County”
“Henry W Yager Fonds”

1860 deaths
Members of the Legislative Assembly of Upper Canada
1802 births
Margaret Darling Woodbridge (January 6, 1902 – February 23, 1995), also known by her married name Margaret Presley, was an American competition swimmer, Olympic champion, and world record-holder.

She represented the United States at the 1920 Summer Olympics in Antwerp, Belgium.  She won the gold medal as member of the winning U.S. team in the women's 4×100-meter freestyle relay.  Woodbridge and her American relay teammates Frances Schroth, Irene Guest and Ethelda Bleibtrey set a new world record of 5:11.6 in the event final.  Individually, Woodbridge received a silver medal for her second-place performance in the women's 300-meter freestyle, finishing behind American teammate Ethelda Bleibtrey, in a time of 4:42.8.

Woodbridge was inducted into the International Swimming Hall of Fame as an "Honor Pioneer Swimmer" in 1989.

See also
 List of members of the International Swimming Hall of Fame
 List of Olympic medalists in swimming (women)
 World record progression 4 × 100 metres freestyle relay

References

External links
 
 

1902 births
1995 deaths
American female freestyle swimmers
World record setters in swimming
Medalists at the 1920 Summer Olympics
Olympic gold medalists for the United States in swimming
Olympic silver medalists for the United States in swimming
Swimmers from Detroit
Swimmers at the 1920 Summer Olympics
20th-century American women
Carl Decaluwé (born 18 September 1960) is a Belgian politician who has been the Governor of West Flanders since 2012. He is a member of Christen-Democratisch en Vlaams.

Early life 
Decaluwé was born in Kortrijk. He graduated from Ghent University.

Political career 
In 2012, he succeeded Paul Breyne as Governor of West Flanders Province.

In June 2020, Decaluwé announced the use of thermographic cameras to combat human trafficking and people smuggling along the North Sea coast.

References

External links 
 Official website

1960 births
Living people
Christian Democratic and Flemish politicians
People from West Flanders
Governors of West Flanders
People from Kortrijk
Ghent University alumni
Stadionul Republicii (, Stadium of the Republic) was a multi-use stadium in Bucharest, Romania.

It was used mostly for football matches. The stadium was able to hold 28,026 spectators at its height and originally opened in 1926. It hosted 42 matches for the Romania national football team, 1 match for the Olympic National Team, 22 Romanian Football Cup finals and 15 European Cup matches.

The stadium was originally built in 1926 as the Stadionul Oficiul Național de Educație Fizică, or simply Stadionul ONEF, and inaugurated on 9 May 1926 with a rugby match against the French army. It was destroyed by fire and rebuilt under the name Stadionul Republicii in 1948.

It is located on Spirii Hill, the current location of the Palace of the Parliament. Since everything on the hill was cleared, including a former social high class and historic neighborhood, the stadium was demolished, but even to this day the ruins of the stands can be seen from above.

There were projects to move the National Football Stadium that would host a UEFA Europa League final between 2010 and 2013 to the same location, but those failed when the city's town hall decided to demolish the Stadionul Național and build a new one dedicated only to football and concerts.

External links
Stadium information and photos

Defunct football venues in Romania
Demolished buildings and structures in Bucharest
FC Steaua București
Tony Koonwaiyou (born 10 June 1983 in Samoa) is a rugby union footballer who plays at wing, centre and fullback for the Southland Stags in the Air New Zealand Cup. He attended Mt Roskill Grammar and Kings College in Auckland, New Zealand.

Rugby career
After a great season in the 2003 NPC for Auckland he was drafted by the Crusaders for the 2004 Super 12. His debut was against the New South Wales Waratahs and went on to play 7 games that season. In 2004 the Koonwaiyou was contracted to play for the Blues but a severe injury halted his rugby future. In 2008 Koonwaiyou signed with Southland but another injury sidelined him for the whole 2008 Air New Zealand Cup. Koonwaiyou finally made his debut off the bench on 1 August 2009 in the Stags 16-6 win over Waikato.

References
 Southland Profile

1983 births
New Zealand rugby union players
New Zealand people of Chinese descent
New Zealand sportspeople of Samoan descent
Otago rugby union players
Rugby union wings
Living people
John Cuthbertson may refer to:
 John Cuthbertson (instrument maker) (1743–1821), English instrument maker living in the Netherlands from 1768 to 1796
 John Cuthbertson (politician) (1834–1882), politician from New Zealand
 John Cuthbertson (footballer, fl. 1939–56), Scottish footballer
 John Cuthbertson (footballer, born 1932), Scottish footballer for Mansfield Town
 John Cuthbertson (cricketer) (born 1942), English cricketer
 John Cuthbertson (Covenanter), Covenanter minister
 John Cuthbertson, see The Last Confession of Alexander Pearce
Alvikia is a monotypic genus of green algae in the class Chlorophyceae. Its taxonomy is uncertain. 
It only contains the known species of Alvikia littoralis.

The genus and species were circumscribed by Shin Watanabe and Louise A. Lewis in Phycologia vol.56 (3) on pages 329-353 in 2017.

The genus name of Alvikia is in honour of Gunnar Ålvik (fl. 1934-1951), who was a Norwegian botanist (Algology) and Professor of plant physiology.
He conducted research in 1936 at the University of Göttingen and later at the University of Oslo. In 1951 he received help from the Rockefeller Foundation for the building of a laboratory and greenhouse space for his department of Plant-physiology.

References

Chlorophyceae genera
Monotypic algae genera
Taxa described in 2017
Chlorophyceae
Cochecton Center Methodist Episcopal Church, also known as Cochecton Center Community Center, is a historic Methodist Episcopal church on Skipperene Road in Cochecton Center, Sullivan County, New York.  It was built in 1892 and is a small, rectangular, wood-frame building with clapboard siding on an ashlar foundation and a steep gable roof.  It features a three-stage, corner entrance tower surmounted by a tall spire.  Also on the property is a former stable, dated to 1912, that was converted for use as a church hall in 1925.

It was added to the National Register of Historic Places in 2000.

References

Methodist churches in New York (state)
Churches on the National Register of Historic Places in New York (state)
Churches completed in 1892
19th-century Episcopal church buildings
Churches in Sullivan County, New York
National Register of Historic Places in Sullivan County, New York
1892 establishments in New York (state)
is an interchange passenger railway station in the city of Nagareyama, Chiba, Japan, operated jointly by the private railway operator Tōbu Railway (as an infill station) and the third-sector railway operating company Metropolitan Intercity Railway Company.

Lines
The station is served by the following two lines.
Tobu Urban Park Line
Tsukuba Express

It is located  from the terminus of the Tobu Urban Park Line at Ōmiya Station, and  from the terminus of the Tsukuba Express at Akihabara Station.

Station layout
Nagareyama-ōtakanomori Station has two opposed side platforms at ground level for the Tobu Urban Park Line, connected by a footbridge to the elevated station building above. The Tsukuba Express has two elevated island platforms built at a right angle to the Tōbu Line platforms, built above the station building. A walkway form the station connects it to the Forest of Nagareyama shopping mall.

Platforms

Tobu

Metropolitan Intercity Railway

History
The station opened on 24 August 2005, coinciding with the opening of the Tsukuba Express line.

From 17 March 2012, station numbering was introduced on all Tōbu lines, with Nagareyama-ōtakanomori Station becoming "TD-22".

Passenger statistics
In fiscal 2018, the Tobu Railway portion of the station was used by an average of 58,635 passengers daily. The Tsukuba Express portion of the station was used by an average of 38,194 passengers (departing passengers only) during the same period.

Surrounding area
Edogawa University
Nagareyama-ōtakanomori Shopping Center
Nagareyama-ōtakanomori Post Office

See also
 List of railway stations in Japan

References

External links

 Tobu Railway Nagareyama-ōtakanomori Station 
 TX Nagareyama-ōtakanomori Station 

Stations of Tsukuba Express
Stations of Tobu Railway
Railway stations in Chiba Prefecture
Railway stations in Japan opened in 2005
Nagareyama
A shithole is a profane term for a dirty or dysfunctional place.  Shithole may also refer to:

Shithole, a song by Les Turds on the compilation album Play at Your Own Risk, Volume 2
Shit Hole, a song on the 2005 film score album Saw II
The Shithole, a spoken word piece on the 2006 album Boned!
Shithole, a 2016 song by Canadian band Weaves

See also
 "Shithole countries", a comment made by Donald Trump in 2018
 Shit
 Shit (disambiguation)
Biyangdo () is an island in South Korea. It is located in the Jeju Province, in the southern part of the country, 500 km south of the capital, Seoul.

References

Islands of Jeju Province
Celaenephes is a genus of beetles in the family Carabidae, containing the following species:

 Celaenephes linearis (Walker, 1858)
 Celaenephes parallelus Schmidt-Gobel, 1846

References

Lebiinae
Gerard Whelan (born 1957), is an Irish writer.

Career overview 
Whelan was born in Enniscorthy, County Wexford, and has lived and worked in several European countries. After some time living in Dublin, he has returned to live in his native Wexford. He is the author of many books for children and is a multiple award-winner. He has also written the non-fiction book Spiked: Church, State Intrigue and the Rose Tattoo and edited the anthology, Big Pictures. He is married and has 1 son called Davy.

The Guns of Easter, A Winter of Spies and War Children are historical novels based on the Irish struggle for independence in the early 20th century, while Dream Invader and Out of Nowhere are fantasy novels.

Bibliography 
The Guns of Easter (O'Brien Press, 1996)
Dream Invader (O'Brien, 1997)
A Winter of Spies (O'Brien, 1998)
Big Pictures (editor) (LETS, 1998)
Out of Nowhere (O'Brien, 1999)
War Children (O'Brien, 2002)
Spiked: Church, State Intrigue and the Rose Tattoo (New Island, 2002)

Awards
The Guns of Easter won the Eilís Dillon Memorial Award for first-time writers and a Merit Award at the 1997 Bisto Book of the Year Awards
Dream Invader won Book of the Year at the 1998 Bisto Book of the Year Awards
War Children won a Merit Award at the 2003 Bisto Book of the Year Awards

References

External links
Gerard Whelan at the O'Brien Press 
 

Living people
Irish novelists
Irish children's writers
Writers from County Wexford
People from Enniscorthy
Irish male novelists
1957 births
This is the discography of electronic dance music producers and DJs Pegboard Nerds.

Albums and extended plays

As featured artists

Singles

Covers 
 The Grid – Swamp Thing (2015, Monstercat)
 Snap! – Rhythm Is A Dancer  (2020, Monstercat)

Remixes

Music videos

References 

Electronic music discographies
Coleophora marcella is a moth of the family Coleophoridae that is endemic to Uzbekistan.

References

External links

marcella
Moths described in 1972
Moths of Asia
Endemic fauna of Uzbekistan
This is a list of Calgary Transit bus terminals that serve destinations Calgary's city limits.

List of Bus Terminals

References

Calgary-related lists
Calgary
Calgary Transit
Bus stations, Calgary
Bus stations in Alberta
Greta Kiernan ( Spier, December 20, 1933 – January 3, 2023) was an American Democratic Party politician who served in the New Jersey General Assembly from the 39th Legislative District from 1978 to 1980.

Kiernan attended the Academy of the Holy Angels and Berkeley School of Business. She first worked as a lobbyist for the League of Women Voters. Prior to her elected Assembly term, she served as an aide to other Bergen County Democratic legislators Harold Martin, Matthew Feldman, and Albert Burstein. At the time a resident of Harrington Park, she ran for the General Assembly in 1977 where she and incumbent Democratic running mate Harold Martin defeated Republicans Demarest mayor Gerald Cardinale and John Inganamort among others. At the time of her election, she was the first Democratic woman elected to the legislature from Bergen County. While in the Assembly, she served on the Joint Appropriations Committee, the Legislative Oversight Committee, and the State Government Committee.

Kiernan served a single term in the General Assembly before she and Martin, were defeated by Cardinale and former Assemblyman John Markert in the 1979 elections. She later worked on the staff of State Senator Paul Contillo, U.S. Representative Rush Holt Jr., and Governors Jim McGreevey, Richard Codey, and Jon Corzine. In 1989, by now a resident of Hackensack, she ran for the General Assembly again (from the 38th District) but was defeated by Republican incumbents Patrick J. Roma and Pat Schuber. Kiernan moved to Plainsboro Township where she served on the township planning board and as a trustee of the township library.

Kiernan died on January 3, 2023, at the age of 89.

References

1933 births
2023 deaths
Democratic Party members of the New Jersey General Assembly
Politicians from New York City
People from Harrington Park, New Jersey
Politicians from Hackensack, New Jersey
People from Plainsboro Township, New Jersey
Women state legislators in New Jersey
20th-century American politicians
20th-century American women politicians
The 1986 Commonwealth Heads of Government Meeting was the ninth Meeting of the Heads of Government of the Commonwealth of Nations.  It was held in London, the United Kingdom, between 3 August 1986 and 5 August 1986, and was hosted by that country's Prime Minister, Margaret Thatcher. This was a special meeting held in between the biennial CHOGMs in order to consider the recommendations of the Commonwealth Eminent Persons Group regarding economic sanctions against South Africa due to its policies of apartheid. British prime minister Margaret Thatcher's refusal to support mandatory sanctions resulted in an acrimonious meeting and almost led to a split in the Commonwealth. 
 

1986
Diplomatic conferences in the United Kingdom
20th-century diplomatic conferences
1986 conferences
1986 in international relations
1986 in the United Kingdom
United Kingdom and the Commonwealth of Nations
August 1986 events in the United Kingdom
1986 in London
Events in London
1980s in the City of Westminster
The Sea Lady is a 2006 novel written by the English author Margaret Drabble.

References

 
 
 

2006 British novels
Novels by Margaret Drabble
Penguin Books books
Parnassius behrii, the Sierra Nevada parnassian, is a species of butterfly in the family Papilionidae. It is native to the Sierra Nevada of California, US, where it is found in habitats such as rock slides, alpine tundra, and stream edges. Adults use members of the family Asteraceae as nectar plants, and both adults and larvae use Sedum species as nectar and host plants. P. behrii has one flight from mid-July to early September.

The wingspan measures . The dorsal forewing has two black spots and one to three yellow-orange spots along the costa. The hindwing has two yellow-orange spots. The abdomen has pale yellow hairs.

Males fly close to the ground when searching for females. The eggs are laid singly on many surfaces. The caterpillars feed on the leaves of the host plant and will sometimes consume the flowers and seeds. P. behrii hibernates as an egg.

Description
A rather large form, in which the male usually has somewhat longer wings, the submarginal band is marked anteriorly by sharp black luniform spots, which become obsolete posteriorly, the anterior ones of the costal spots usually centred with red, the glossy border is confined to the anterior half, narrowed and so restricted by the white marginal spots that it only remains as a row of blackish wedge-shaped spots; ocelli of the hindwing small. The red yellow colouring of the ocelli and the development of small submarginal spots on the hindwing are given as special characteristics, but these features are not constant. The females as a rule have the costal spots on the forewing strongly filled in with red, a strongly marked submarginal band, the disc more or less dusted with black, on the hindwing the submarginal lunules are confluent as a sort of band and there are grey spots at the margin itself. The aspect on the whole like sayii female or a lighter hermodur [sayii var.] -female. California (Sierra Nevada), Utah.

Etymology
The species name honours Hans Hermann Behr.

References

External links
Funet
Butterflies of America images including holotype
P. behrii images  at  Consortium for the Barcode of Life

behrii
Butterflies described in 1870
Abdul Kahar Mim (born 6 November 1968) is an Indonesian former professional tennis player.

Kahar Mim, born and raised in Samarinda on the island of Borneo, was a Southeast Asian Games gold medalist for Indonesia in 1987. His only Davis Cup appearance was in a 1989 World Group tie against reigning champions West Germany in Karlsruhe, where he lost singles rubbers to Boris Becker and Carl-Uwe Steeb.

See also
List of Indonesia Davis Cup team representatives

References

External links
 
 
 

1968 births
Living people
Indonesian male tennis players
SEA Games medalists in tennis
SEA Games gold medalists for Indonesia
SEA Games bronze medalists for Indonesia
Competitors at the 1987 SEA Games
People from Samarinda
Sportspeople from East Kalimantan
František Hadaš (born 22 March 1941) is a Czech archer. He competed in the men's individual event at the 1980 Summer Olympics.

References

1941 births
Living people
Czech male archers
Olympic archers for Czechoslovakia
Archers at the 1980 Summer Olympics
Sportspeople from Zlín
Joshua B. Plotkin is an evolutionary biologist and applied mathematician. He is the Walter H. and Leonore C. Annenberg Professor of Natural Sciences at the University of Pennsylvania. Plotkin's research includes the study of the evolution of adaptation in populations, virus ecology, genetic drift, protein translation, and social norms.

He serves on the editorial boards for Science Magazine and Cell Reports.

External links
 Plotkin Research Group website

References

Living people
Mathematical ecologists
21st-century American biologists
American ecologists
University of Pennsylvania faculty
Walter H. Annenberg Professor
Mathematicians at the University of Pennsylvania
University of Pennsylvania Department of Biology faculty
Princeton University alumni
Harvard University alumni
Year of birth missing (living people)