Lopes is a surname of Portuguese origin. It was originally a Patronymic, meaning Son of Lopo, itself being derived from Latin lupus, meaning wolf. Its Spanish equivalent is López, its Italian equivalent is Lupo, its French equivalent is Loup, and its Romanian equivalent is Lupu or Lupescu. Notable people with the surname include:

Álvaro Lopes Cançado (1912–1984), Brazilian
Adelino Lopes (born 1976), Guinea-Bissaun
Adriane Lopes (born 1976), Brazilian politician
Alexandre Paes Lopes (born 1974), Brazilian footballer
Almir Lopes de Luna (born 1982), Brazilian
Américo Lopes (born 1933), Portuguese footballer
Amílcar Lopes Cabral (1924–1973), Capeverdian and Guinea-Bissau Statesman.
Ana Paula Lopes (born 1979), Brazilian singer
Aniceto Guterres Lopes (born 1967), East Timorese
António Bastos Lopes (born 1953), Portuguese
António Lopes Ribeiro (1908–1995), Portuguese
Antônio Lopes (born 1941), Brazilian
Astolpho Junio Lopes (born 1983), Brazilian
Baltasar Lopes da Silva (1907–1989), Capeverdian
Brian Lopes (born 1971), United States
Carlos Eduardo Lopes (born 1980), Brazilian footballer
Carlos Lopes (born 1947), Portuguese long-distance athlete
Carlos Michel Lopes Vargas (born 1982), Brazilian
Cecilio Lopes (born 1979), Dutch
Christian Lopes (born 1992), American
Cristóvão Lopes (c.1516–1594), Portuguese painter
Daniel Lopes (born 1976), German singer
Danny Lopes (born 1982), United States
Davey Lopes (born 1945), United States baseball player and manager
Demetrius Klee Lopes (born 1970), Brazilian-American cerebrovascular neurosurgeon
Dirceu Lopes (born 1946), Brazilian
Ephraim Lópes Pereira d'Aguilar, 2nd Baron d'Aguilar (1709–1832), British
Ernando Rodrigues Lopes (born 1988), Brazilian
Everton Lopes (born 1988), Brazilian
Felipe Aliste Lopes (born 1987), Brazilian
Fernando Lopes (1935–2012), Portuguese filmmaker
Fernando Lopes-Graça (1906–1994), Portuguese
Fernão Lopes (c.1380–1459), Portuguese royal chronicler
Fernão Lopes (died 1545), Portuguese sailor and first inhabitant of the island of Saint Helena
Francisco Craveiro Lopes (1894–1960), Portuguese politician and military
Fábio Deivison Lopes Maciel (born 1980), Brazilian
Fábio Lopes Alcântara (born 1977), Brazilian
Fátima Lopes (born 1965), Portuguese
Giulio Lopes (born 1959), Brazilian actor
Gregório Lopes (c.1490–1550), Portuguese painter
Henrique Lopes de Mendonça (1856–1931), Portuguese
Henry Lopes, 1st Baron Roborough (1859–1938), British Member of Parliament
Joao Abel Pecas Lopes, Portuguese engineer
John Reginald Lopes Yarde-Buller, 3rd Baron Churston (1873–1930), British
João Simões Lopes Neto (1865–1916), Brazilian
Júlio Lópes (born 1967), Brazilian swimmer
Laura Lopes (born 1978), daughter of Camilla, Duchess of Cornwall and Andrew Parker Bowles, OBE
Leandro Lopes (born 1984), Brazilian
Leila Lopes (born 1986), Angolan Miss Universe 2011 winner.
Lisa Lopes (1971–2002), United States
Lopes Gonçalves, Portuguese explorer
Luciano Lopes de Souza (born 1974), Brazilian
Luís Carlos Melo Lopes (1954–2016), Brazilian footballer
Manuel Lopes (barber) (before 1850–after 1870), United States barber and first Black resident of Seattle
Manuel Lopes (1907–2005), Capeverdian writer
Marcelo Gonçalves Costa Lopes (born 1966), Brazilian footballer
Marcelo Lopes de Faria (born 1976), Brazilian
Maria do Couto Maia-Lopes (1890-2005) Portuguese supercentenarian
Martinho da Costa Lopes (1918–1991), East Timorese religious and political leader
Massey Lopes, 2nd Baron Roborough (1903–1992),  British peer and officer of the British Army
Mateus Lopes (born 1972), Capeverdian
Matheus Henrique do Carmo Lopes (born 1985), Brazilian
Mécia Lopes de Haro (died 1270), Portuguese
Nei Lopes (born 1942), Brazilian musician
Neylor Lopes Gonçalves (born 1987), Brazilian
Olga Lopes-Seale (1918–2011), Barbadian
Oscar Lino Lopes Fernandes Braga (1931–2020), Angolan
Osvaldo Lopes (born 1980), French
Patrick Fabíonn Lopes (born 1980), Brazilian footballer
Paulo José Lopes de Figueiredo (born 1972),  Angolan
Pedro Santana Lopes (born 1956), Portuguese
Rinaldo Lopes Costa (born 1968), Brazilian
Roberto Lopes (born 1966), Brazilian
Roberto Lopes Nascimento (born 1983), Brazilian
Rosaly Lopes (born 1957), Brazilian earth-scientist
Santinho Lopes Monteiro (born 1979), Dutch
Sir Manasseh Masseh Lopes, 1st Baronet (1755–1831), British Member of Parliament
Sir Massey Lopes, 3rd Baronet (born "Massey Franco" 1818–1908), British Member of Parliament
Sir Ralph Lopes, 2nd Baronet (born "Ralph Franco" 1788–1854), British Member of Parliament
Steven J. Lopes (born 1975), Portuguese American Roman Catholic Bishop of the Personal Ordinariate of the Chair of Saint Peter
Sufrim Lopes (born 1981), Guinea-Bissaun
Tiago André Coelho Lopes (born 1989), Portuguese
Tim Lopes (1950–2002), Brazilian
Elvira Tânia Lopes Martins (born 1957), Brazilian
Valmiro Lopes Rocha (born 1981), Spanish
Wagner Lopes (born 1969); Japanese footballer
Welington Nogueira Lopes (born 1979), Brazilian footballer
Wesley Lopes Beltrame (born 1987), Brazilian
Wesley Lopes da Silva (born 1980), Brazilian

Galician-language surnames
Portuguese-language surnames
Patronymic surnames