Samantha912/NLP_A2_WTH huggingface dataset:
A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate.  The acceptor substrate can be another sugar such as the transfer of a fucose to a core GlcNAc (N-acetylglucosamine) sugar as in the case of N-linked glycosylation, or to a protein, as in the case of O-linked glycosylation produced by O-fucosyltransferase.  There are various fucosyltransferases in mammals, the vast majority of which, are located in the Golgi apparatus.  The O-fucosyltransferases have recently been shown to localize to the endoplasmic reticulum (ER).

Some of the proteins in this group are responsible for the molecular basis of the blood group antigens, surface markers on the outside of the red blood cell membrane. Most of these markers are proteins, but some are carbohydrates attached to lipids or proteins [Reid M.E., Lomas-Francis C. The Blood Group Antigen FactsBook Academic Press, London / San Diego, (1997)]. Galactoside 3(4)-L-fucosyltransferase () belongs to the Lewis blood group system and is associated with Le(a/b) antigen.

Classification
Glycosyltransferase family 10 CAZY GT_10 comprises enzymes with two known activities; galactoside 3(4)-L-fucosyltransferase () and galactoside 3-fucosyltransferase (). The galactoside 3-fucosyltransferases display similarities with the alpha-2 and alpha-6-fucosyltranferases. The biosynthesis of the carbohydrate antigen sialyl Lewis X (sLe(x)) is dependent on the activity of an galactoside 3-fucosyltransferase. This enzyme catalyses the transfer of fucose from GDP-beta-fucose to the 3-OH of N-acetylglucosamine present in lactosamine acceptors.

Role in preventing UTIs
Robust fucosyltransferase activity discourages bacterial adherence in the urethra of women. This is also mediated by the presence of few bacterial adhesion sites in the bladder and urethra. Women with these receptors who do not have mucosal secretion of the fucosyltransferase enzyme to help block bacterial adherence are more likely to have colonization of E. coli and other coliforms from the rectum and less likely to have lactobacilli in the periurethral area, resulting in frequent episodes of cystitis.

Human proteins containing this domain 
FUT1; FUT2; FUT3; FUT4; FUT5; FUT6; FUT7; FUT8; FUT9; FUT10; FUT11;

See also
 fucosylation

References

External links
 

Transferases
EC 2.4.1
Mount Kidd is a  double-summit massif centrally located in Kananaskis Country in the Canadian Rockies of Alberta, Canada. Mount Kidd is situated within Spray Valley Provincial Park, and its nearest higher neighbor is Mount Sparrowhawk,  to the northwest. Mount Kidd is a landmark that can be seen from Highway 40 in the Kananaskis Village area, and from the Kananaskis Country Golf Course which lies at the eastern base of the mountain.

History
In 1907, Dr. Donaldson Bogart Dowling, an engineer with the Geological Survey of Canada, named the mountain for John Alfred (Fred) Kidd, who was a resident of nearby Morley, Alberta. From 1902 to 1907, Kidd ran the Morley general store and outfitted expeditions and geological survey crews such as Dowling's with supplies. The first ascent of the mountain was made in 1947 by R. C. Hind and J. F. Tarrant. The mountain's name was officially adopted in 1953 by the Geographical Names Board of Canada. In June 1986, Mount Kidd was the scene of the first of three related airplane crashes known as the Rescue 807 Crashes. In August 2010, James Hoshizaki stepped onto a snow cornice to pose for a photo when it gave way, resulting in an avalanche that swept him down about 200 metres to his death.

Geology
Mount Kidd is composed of sedimentary rock laid down during the Precambrian to Jurassic periods. Formed in shallow seas, this sedimentary rock was pushed east and over the top of younger rock during the Laramide orogeny. The Lewis Overthrust extends over 450 km (280 mi) from Mount Kidd south to Steamboat Mountain, located west of Great Falls, Montana. Mount Kidd marks the northern end of the Lewis Thrust Fault.

Climate
Based on the Köppen climate classification, Mount Kidd is located in a subarctic climate zone with cold snowy winters and mild summers. Temperatures can drop below −20 °C (−4 °F) with wind chill factors  below −30 °C (−22 °F). Weather conditions during winter make Mount Kidd one of the better places in the Rockies for ice climbing. Precipitation runoff from the mountain drains into the Kananaskis River which is a tributary of the Bow River, and thence the Saskatchewan River.

Climbing
Mount Kidd has two summits, a north and south peak, each with scramble routes. The more massive north peak is the true summit at , whereas the lesser south peak rises to . Additionally, Mount Kidd has a class 5.7 rock climbing route on its northeast buttress, as well a 5.8 route called The Fold on the south peak. In 1985, Rudi Kranabitter and Ferdl Taxbock made the first ascent of this now-classic route.

Ice Climbing Routes with grades on Mount Kidd:

 A Bridge Too Far – WI4+
 Kidd Falls – WI4
 Tasting Fear – WI5−
 Wedge Smear – WI3
 Sinatra Falls – WI2

Gallery

See also

Scrambles in the Canadian Rockies
List of mountains of Canada
Geography of Alberta

References

External links

 Mount Kidd weather web site: Mountain Forecast
 Drone video at Mount Kidd: YouTube
 Mt. Kidd reflection photo: Flickr

Alberta's Rockies
Two-thousanders of Alberta
Canadian Rockies
The Château du Bec-Crespin is a historic castle in Saint-Martin-du-Bec, Seine-Maritime, Upper Normandy, France, 20 km north of Le Havre.  It is now a luxury hotel.

History
An earlier castle stood here in the tenth century.

The castle was inherited by Pierre de Brézé from his brother-in-law, Antoine Crespin, in 1454. It was later inherited by Louis de Brézé. In 1579, it was acquired by Nicolas Romé de Fresquiennes.

During the Reign of Terror, the castle was used as a prison for Roman Catholic priests. The castle was restored in 1844–48.

The castle was rented to Henri Carton de Wiart from 1916 onwards, when he was the Belgian Minister of Justice. Guests included Maurice Barrès, Louis Barthou and René Bazin.

The castle is now a luxury hotel.

Architectural significance
It has been listed as an official historical monument since December 22, 1952.

References

External links

Official website

Châteaux in Seine-Maritime
Monuments historiques of Seine-Maritime
Hotels in France
The Sunday Post is a weekly newspaper published in Dundee, Scotland, by DC Thomson, and characterised by a mix of news, human interest stories and short features. The paper was founded in 1914 and has a wide circulation across Scotland, Northern Ireland, and parts of Northern England.

The current editor is Richard Prest.

Sales of the Sunday Post in Scotland were once so high that it was recorded in The Guinness Book of Records as the newspaper with the highest per capita readership penetration of anywhere in the world; in 1969, its total estimated readership of 2,931,000 represented more than 80 per cent of the entire population of Scotland aged 16 and over. The Sunday Post has seen a decline in circulation in common with other print titles; in 1999 circulation was around 700,000, dropping to just under 143,000 in December 2016, with a year-on-year fall of 13.5% recorded for 2016.

2007 saw DC Thomson launch an advertising drive for The Sunday Post, primarily used on buses, in which the exclamation "Strip Sensation!" is seen by a picture of the folded paper displaying its masthead; next to this is the tagline punning on the exclamation: "A thoroughly decent read".

The newspaper backed a "No" vote in the referendum on Scottish independence.

In 2014 a weekly magazine supplement was reintroduced. Called IN10, it features entertainment, food, homes, gardens, travel and books as well as The Sunday Post'''s man in Hollywood, Ross King.

Regular features
Regular columns include:My Week by Francis Gay (a generic character), featuring sentimental stories and a weekly short poemThe Honest Truth – question and answer celebrity interview featureRaw Deal – consumer problemsThe Doc Replies – medical adviceCan You Do Me a Favour? – readers asking if fellow readers can help them in their quest to find an item (discontinued)The Queries Man – readers send in questions on a range of topics, which an unnamed person answersYour Money - Personal finance feature.On The Box - TV review column.

Former long-running columns includedThe HON Man – (a generic character), an unidentifiable peripatetic man (represented by a cartoon in all his photographs, and reputedly a team of reporters), who travelled Britain, meeting people and exploring local tourist attractions (HON being short for "Holiday on Nothing").

Comics
There is a Fun Section featuring comic strips such as:Oor WullieThe BroonsWee HarryWor NickyComic strips that no longer appear include:Nosey Parker Our Muddling MeddlerNero and Zero The Rollicking RomansSilias Snatcher The Truant CatcherWishbone WuzzyAusten and his AutoBarnacle BillFunny CornerPeter Pumpkin The Country BumpkinNatty NedWee Jock SparraThe Broons' BairnEditors
2001: David Pollington
2010: Donald Martin
2015: Richard Prest

See alsoThe People's Friend''
List of newspapers in Scotland
List of DC Thomson Publications
Ron Scott

References

External links
 

Newspapers published in Scotland
Mass media in Dundee
Newspapers established in 1914
Scottish brands
1914 establishments in Scotland
Wetterhorn Peak (, literally "weather horn") is a fourteen thousand-foot mountain peak in the U.S. state of Colorado. It is located in the Uncompahgre Wilderness of the northern San Juan Mountains, in northwestern Hinsdale County and southeastern Ouray County, approximately  east of the town of Ouray and  west of Uncompahgre Peak.

Wetterhorn Peak and neighboring Matterhorn Peak () are named after the Wetterhorn and the Matterhorn, two famous peaks in the Swiss Alps. Both Colorado peaks are pointed rock spires (hence resembling their namesake peaks), whose shapes contrast with the broad bulk of the higher Uncompahgre Peak.

The first recorded ascent of Colorado's Wetterhorn was made in 1906 by George Barnard, C. Smedley, W. P. Smedley, and D. Utter, but a previous ascent by miners working in the area in the 19th century is likely.

The standard route to the summit of Wetterhorn Peak ascends the southeast ridge, which is accessed via the Matterhorn Creek drainage on the south side of the mountain. The trailhead is on the Henson Creek Road, accessible from Lake City. The route involves  of ascent from the trailhead and some exposed scrambling (Class 3/4) on the ridge itself. The nearby east face is considered a high-quality advanced snow climb or extreme ski descent.

See also

List of mountain peaks of Colorado
List of Colorado fourteeners

References

External links

 
Wetterhorn Peak on Distantpeak.com

Mountains of Hinsdale County, Colorado
Mountains of Ouray County, Colorado
Fourteeners of Colorado
North American 4000 m summits
San Juan Mountains (Colorado)
Uncompahgre National Forest
Mountains of Colorado
Marden is a surname. Notable people with the surname include:

 Adrienne Marden (1909–1978), American actress
 Albert Marden (born 1934), American mathematician
 Brice Marden (born 1938), American artist
 John Louis Marden (1919–1999), British businessman and philanthropist
 Dr John Marden (1855–1924), Australian headmaster, pioneer of women's education, and Presbyterian elder
 Luis Marden (1913–2003), American photographer and explorer for the National Geographic
 Orison Swett Marden (1848–1924), American writer
 Robert A. Marden (born 1927), American politician and attorney
 Thomas Marden (1866–1951), British major general
Qalatak () may refer to:
 Qalatak, Chaharmahal and Bakhtiari
 Qalatak, Fars
 Qalatak, Kohgiluyeh and Boyer-Ahmad
Adrian Stokes (4 March 1519 – 3 November 1585) was an English courtier and politician.

Stokes was probably a younger son of a gentry family from Prestwold, Leicestershire. He became Master of the Horse to Frances Grey, Duchess of Suffolk, and married her on 1 March 1555, just over a year after the execution of her first husband, Henry Grey, 1st Duke of Suffolk. They had three children, all of whom died in infancy. Following the accession of Elizabeth I, rumours circulated that the queen would like to marry her master of the horse Robert Dudley, later earl of Leicester in emulation of the former French queen and Stokes.

The Duchess of Suffolk died in 1559, leaving Stokes a life interest in most of her land. The manors he held included Beaumanor, Leicestershire and he was elected to the English House of Commons as knight of the shire (MP) for Leicestershire in 1559. In 1564 Stokes was classified by his bishop as a committed Protestant, and he served on local commissions to enforce attendance at church and to discover recusants.

Stokes was elected for Leicestershire again in 1571. In October 1571 his step-daughter Lady Mary Grey asked to be allowed to live with her step-father at Beaumanor. The following year Stokes married Anne Carew, daughter of Sir Nicholas Carew and widow of Sir Nicholas Throckmorton, an eminent diplomat and politician. By her first marriage Anne was the mother of ten sons and three daughters. Once Stokes was safely remarried, Lady Mary was allowed to live at Beaumanor. Stokes succeeded Throckmorton as keeper of Brigstock park, Northamptonshire.

Although his second marriage brought him control of the considerable Throckmorton estates, he also became responsible for the court expenses and dowries of his Throckmorton stepdaughters. The keepership of Brigstock also involved him in legal disputes over poaching and other encroachments. In Warwickshire he became notorious for the damage caused to the church at Astley, where he pulled down the spire rather than repair it and stripped the roof of its valuable lead. He died in 1585 and was buried in the chapel at Beaumanor.

References

1519 births
1586 deaths
Court of Henry VIII
English courtiers
English MPs 1559
English MPs 1571
English Protestants
Members of the Parliament of England for Leicestershire
Mali Bero (Mali the Great or Eldest) or Zarmakoy Sombo is a mythical legendary leader of the Zarma people of western Niger who led them in their migration from an unknown region in Mali eastward to western Niger several centuries ago. The story of Mali Bero has appeared in various forms in the Zarma society from poems, songs and oral narratives by griots. No one, however, has published a linear version of the story of Mali Bero that is more than a few hundred lines long. Mali Bero, however, is believed to be the son of Zabarkane, another Zarma legendary figure

Oral Tradition
For the Zarmas, the most important message is their migration eastward led by Mali Bero via "Barma Daba", a flying millet silo bottom (a flat and round surface made of wooden straw that serves as foundation for a temporary silo). The incident that prompted the migration, which was the fight between the Zarma, Tuareg and Fulani children reflects an history of an on-and-off conflict that marks relations with these three groups until today.

Migration
According to oral tradition, Mali Bero decided one day to leave his village following a fight between one of his villagers and a child from neighboring village of the Fulani and Tuareg during a swim in the pond of "Mallé". The children of these villages had the habit of taking the clothes of the children from the village of Mali Béro to wipe their bodies after taking their baths in the pond. The children from the village of Mali Béro decided one day not to accept this and planned a revenge if the act is repeated. When the act was repeated, one child from the other village was killed by another child from the village of Mali Bero. Upon hearing the news that one of his offspring has killed a child from the neighboring village, Mali Béro gathered his village and offered them to leave urgently to prevent the situation from degenerating in the event the other village decide to  take revenge. He ordered them to urgently collect millet stalks for making the “Barma Daba”. Quickly, they made the "Barma Daba" in which they entered to embark on a flight in search for a new territory. After series of stops, they finally landed in Sargane, a village in present-day Niger . Mali Béro remained in Sargane until he died. He is buried in this same village which is found in the Ouallam Department. The tomb where Mali was buried remains an attraction for tourists, students and researchers.

References

History of Niger
Zarma people
16th-century Muslims
Year of birth uncertain
Werner Stauffacher was supposedly the name of the representative of the canton of Schwyz, one of the three founding cantons at the legendary Rütlischwur of 1291, as told by Aegidius Tschudi.

Many members of the Stauffacher family held the office of Landammann of Schwyz during the 13th and 14th century, most notably among them a certain Werner Stauffacher, leader of the Confederate troops at the Battle of Morgarten. According to legend, his wife was Gertrud Stauffacher.

In Zürich, a tram stop (Stauffacher), a street, a bridge and a quai are named for Stauffacher. In December 2003, the city renamed a square from "Stauffacherplatz" to Ernst-Nobs-Platz, as it was confused with the tram stop. In other Swiss towns, there are "Stauffacherstrasse" (Arbon, Bätterkinden, Berne, Emmenbrücke, Schaffhausen, St. Gallen), "Via Stauffacher" (Lugano), "Im Stauffacher" (Bennau) or a "Stauffacherweg" (Lucerne, Solothurn, Zuchwil).

13th-century Swiss people
William Tell
Winamac Fish and Wildlife Area is a protected area dedicated to providing hunting and fishing opportunities while maintaining  of oak forest and upland fields. It is located on U.S. Route 35, north of Winamac, Indiana.

In the 1930s, The U.S. Department of the Interior purchased  of marginal farm land along the Tippecanoe River. The land was developed as a recreation demonstration area. In 1943, the property given to the State of Indiana as Tippecanoe River State Park. In 1959, the  moved to the Division of Fish and Game.

Facilities
Wildlife Viewing
Ice Fishing
Hunting
Trapping
Shooting Range
Archery Range
Dog Training Area

References

Parks in Indiana
Protected areas of Pulaksi County, Indiana
1943 establishments in Indiana
Protected areas established in 1943
The Yilin Press () is a publishing house established in 1988, as a division of Phoenix Publishing & Media, Inc. (), and focused on academic publishing. Its office in Nanjing, capital of Jiangsu province, China.  Its current director is Gu Aibin () and the editor-in-chief is Liu Feng ().

References

External links
  

Book publishing companies of China
Publishing companies established in 1988
Mass media in Nanjing
Bracey is a census-designated place (CDP) in Mecklenburg County, Virginia, United States. It is located next to South Hill, La Crosse, and Brodnax also in Mecklenburg County.  The CDP had an estimated population of 1,554 in 2010.

History
Bracey is located along a former railroad mainline. The Richmond, Petersburg and Carolina Railroad, passing through Bracey from Petersburg, Virginia to Ridgeway Junction (today Norlina, North Carolina), was completed in 1900, at which point it was merged into the Seaboard Air Line (SAL). The railroad constructed a depot for Bracey, which was still standing as of 2021. By 1914, the population of Bracey was estimate by the railroad to be somewhere around 200. The line (dubbed the "S-line" after later mergers) continued to operate until the 1980s, and today Bracey is along the abandoned portion of the CSX Norlina Subdivision.

Geography and climate
Bracey is located at  (36.599589, −78.143051). It lies 341 feet (104 m) above sea level.

Bracey lies in the Piedmont area of Virginia and has a humid sub-tropical climate generalized by hot, humid summers and cool to chilly winters. The average annual rainfall is 42.7 inches with winter-time snowfall averaging 3.5 inches.

Demographics
As of the census estimates of 2007, the population of the ZCTA (ZIP Code Tabulation Area) for 23919 was 1,981 people, an increase of 6.02% from the 2000 census.
As of July 1, 2020 total population listed is 2539 (100%). Population in Households 2538 (100%). Population in Families 2038(80.3%). Population in Group 1(0.0%). Quarters 1.
Population Density 88

Lake Gaston 
Bracey is the closest access point to Lake Gaston from Interstate-85. Bracey is home to over 20 businesses and thrives off of visitors to the Lake. It is home to Americamps camping grounds and Poplar point Marina as well as multiple real estate agencies and two private golf clubs. The lake is popular for its fishing and water sports and is broken into four major quadrants. Bracey is the main town in the North West Quadrant.

Economy
Local industry breakdown by occupation is 44.13% sales and professional, 19.47% construction and maintenance, 15.36% production and transportation, 9.92% foodservice and associated services, 9.67% management and financial services, and 1.45% agriculture.

References

External links
 Bracey, Virginia online
 Bracey, VA Info

Census-designated places in Mecklenburg County, Virginia
Census-designated places in Virginia
Kurdistan Women's League (, ) is a women's organization in Iraqi Kurdistan, tied to the Kurdistan Communist Party. Nahla Hussain al-Shaly, the leader of the organisation, was murdered in 2008.

References 

Communist Party of Kurdistan – Iraq
Women's organizations based in Iraq
Women's wings of communist parties
Women in Kurdistan
Pata is a village on the island of Upolu in Samoa. It is in the political district of A'ana.

The population is 487.

References

Populated places in A'ana
António Filipe Dias Melo Peixoto (born December 5, 1981) also known as Filipe Melo is a Portuguese businessman and politician of the Chega party and a member of the Assembly of the Republic for the Braga electoral district.

Biography
Melo was born in 1981. He holds a degree in international relations and worked as a banker at Banco Espírito Santo before becoming a business manager in 2016.

He was elected as a municipal councilor in Braga. For the 2022 Portuguese legislative election, he was elected to the Assembly of the Republic for the Braga constituency. He currently sits on the committees for the economy, housing and urban planning.

Melo encountered some controversy for a 2020 Facebook post in which he criticized a party colleague of Chega Cibelli Pinheiro de Almeida, the then chairwoman of the Braga branch of the party following the possible postponement of the district elections and referenced the fact Almeida was born in Brazil. Melo wrote  It will not be a Brazilian who will rule the fate of a nationalist party… If a Brazilian doesn't care about the future of the Party and our leader, let's show what race we are made of. Almeida responded by accusing Melo of xenophobia and responded by stating What is the real reason for being persecuted? Is it because I am Christian, Brazilian, white or female?

References

1981 births
Portuguese politicians
21st-century Portuguese politicians
Chega politicians
Members of the Assembly of the Republic (Portugal)
Living people