This is why i so love this website ! I saw this film in the 1980's on British television. Over the years it is one i have wished i knew more about as it has stayed with me as one of the single most extraordinary things i have ever seen in my life. With barely a few key words to remember it by, i traced the film here, and much information, including the fact it's about to become an off-Broadway musical !
Interestingly, unlike the previous comment maker, i do not remember finding this film sad, or exploitative. On the contrary, the extraordinary relationship between the mother and daughter stuck in the mind as a testimony of great strength, honour and dignity. Ironic you may think, considering the squalor of their lives. Maybe it's because i live in Britain, where fading grandeur has an established language in the lives of old money, where squalor is often tolerated as evidence of good breeding; I saw it as a rare and unique portrayal of enormous spirit, deep and profound humour, whose utterly fragile and delicately balanced fabric gave it poise and respect. In a way i was sorry to see it being discussed as a 'cult'. Over the years, as it faded in my mind, it shone the brightest, above all others as a one off brilliant & outstanding televisual experience. It was such a deeply private expose, it seems odd to think of it becoming so public as to be a New York musical. But perhaps somewhere, the daughter will be amused by such an outcome. It is she who will have the last laugh maybe..(They made a musical out of her before you Jackie O' )

Nightmare Weekend is proof positive that some people are so desperate to be 'in the movies' they are prepared to do almost anything.
I'm not referring to the countless women who seem quite happy to appear completely starkers in this dreadful piece of trash (after all, the naked female form is a beautiful thing and nothing to be ashamed of). No...I'm talking about those who are more than willing to co-star with a badly made hand-puppet called George. Now that is embarrassing!!!
A bio-electronic being created by brilliant scientist Edward Brake (Wellington Meffert), George (who looks like a demented felt clown with green wool for hair) is the artificially intelligent interface for an advanced computer system that operates a revolutionary device (a silver sphere about the size of a golf ball) that, when ingested, can reverse character disorders.
Edward's personality altering experiments have been successful on lab animals, but the cautious scientist is reluctant to carry out tests on human subjects, fearing that there may still be side effects. His evil assistant Julie (Debbie Laster), however, has no such qualms, and proceeds to use three beautiful young women as guinea pigs. Inevitably, they all turn into hideous killer mutants.
With bargain basement special effects, a cast totally devoid of talent, and a plot that is almost impossible to follow (I took notes as I watched the film, and even then I am not entirely convinced that my synopsis is accurate), Nightmare Weekend is a complete and utter disaster that not even several soft-core sex scenes and a touch of gore can rescue.
This film also features one of the most irritating characters I have ever seen in a horror movie: Tony (Bruce Morton), a Walkman wearing idiot who bops away to crap 80s music in a manner that makes me look like Justin Timberlake in comparison.